LOCUS       DAXIDM010000001        48101 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000001 DAXIDM010000000
VERSION     DAXIDM010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 48101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48101
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.001"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(78..1964)
                     /gene="uvrC"
                     /locus_tag="ACFOAE_000001"
     CDS             complement(78..1964)
                     /gene="uvrC"
                     /locus_tag="ACFOAE_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFC6883584.1"
                     /translation="MPSEAVFQIIDMNTENRSPEQFDIPLFLKNLPKLPGVYRFFDEG
                     GKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTITRSEAEALILENNLI
                     KALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFGPYPNSNAVRDSIQ
                     VLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDSVRQAATFLNGK
                     TDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPNNPNDIDLLA
                     LAVSDGIVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAEAFVAQHYLGKSKPDI
                     IISNFPMPDALKEALESEHGKQMQFVTKTIGERKVWLKMAEQNAQMAIAQRRLQQSSQ
                     QHRIDELAKILGMDSDGLNRLECFDISHTQGEATIASCVVYDEQNIQPSQYRRYNITT
                     AKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDVVLIDGGKGQIGVAVSVWEELGL
                     HIPLVGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHRFAITGHRK
                     KRDKARVTSSLSEIPGIGSKRRQALLTRFGGLRGVIAASREDLEQVEGISKALAETIY
                     NHLH"
     gene            complement(2019..4181)
                     /locus_tag="ACFOAE_000002"
     CDS             complement(2019..4181)
                     /locus_tag="ACFOAE_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFC6883585.1"
                     /translation="MQQKIRFQIEGMTCQACASRIEKVLNKKDFVESAGVNFASEEAQ
                     VVFDDSKTSVADIAKIIEKTGYGAKEKTEDTLPQPEAEHHIGWRLWLLFTINVPFLIG
                     MAGMMIGRHDWMIPPLWQFALASVVQLWLAIPFYKSAWASIKGGLANMDVLVTIGTVS
                     IYLYSVYMLFFSPHAAYGMAHVYFEVGVMVIGFVSLGKFLEHRTKKSSLNSLGLLLKL
                     TPTQVNVQRNGEWKQLPIDQVQIGDLIRANHGERIAADGIIESGSGWADESHLTGESN
                     PEEKKAGGKVLAGALMTEGSVVYRDTQLGSQTQLGDMMNALSEAQGSKAPIARVADKA
                     AAAFVPTVVGIALLTFIATWLIKGDWTLALMHAVAVLVIACPCALGLATPAAIMVGMG
                     KAVKHGIWFKDAAAMEEAAHVDAVVLDKTGTLTEGSPQVAAVYCVPDSGFDEDALYRI
                     AAAVEQNAAHPLARAIVSAAQARGLEIPSAQNAQTVVGAGITAEVEGVGLVKAGKAEF
                     AELALPKFSDGVWDIASIVAVSVDNKPIGAFALADALKADTAEAIGRLKKHNIDVYIM
                     SGDNQGTVEYVAKQLGIAHAFGNMSPRDKAAEVQKLKAAGKTVAMVGDGINDAPALAA
                     ANVSFAMKGGADVAEHTASATLMQHSVNQLADALSVSRATLRNIKQNLFFAFFYNILG
                     IPLAALGFLNPVIAGAAMAASSVSVLSNALRLKRVKID"
     gene            4320..5270
                     /gene="trxB"
                     /locus_tag="ACFOAE_000003"
     CDS             4320..5270
                     /gene="trxB"
                     /locus_tag="ACFOAE_000003"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFC6883586.1"
                     /translation="MSQHRKLIILGSGPAGYTAAVYAARANLNPVIITGIAQGGQLMT
                     TTEVDNWPADADGVQGPELMARFLAHAERFGTEIIFDQINAVDLQKRPFTLKGDMGEY
                     TCDALIVATGASAKYLGLPSEEAFAGKGVSACATCDGFFYKNQDVAVVGGGNTAVEEA
                     LYLANIAKTVTLIHRRSEFRAEKIMIDKLMKRVEEGKIILKLESNLQEVLGDDRGVNG
                     ALLKNNDGSEQQIAVSGIFIAIGHKPNTDIFKGQLEMDEAGYLKTKGGTADNVGATNI
                     EGVWAAGDVKDHTYRQAITSAASGCQAALDAERWLGSQNI"
     gene            5426..5794
                     /gene="rpsF"
                     /locus_tag="ACFOAE_000004"
     CDS             5426..5794
                     /gene="rpsF"
                     /locus_tag="ACFOAE_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFC6883587.1"
                     /translation="MRHYEIVFIVHPDQSEQVPAMVERYKTMIAEANGKIHRLEDWGR
                     RQLAYPINKIHKAHYVLMNIETTPEVVEELETAFRFNDAVLRHLTIKTKHAVTEASPM
                     LGGEKAKNLLSGASEEAVAQ"
     gene            5795..6097
                     /gene="priB"
                     /locus_tag="ACFOAE_000005"
     CDS             5795..6097
                     /gene="priB"
                     /locus_tag="ACFOAE_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030894 - replisome [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HFC6883588.1"
                     /translation="MGFNNLVSLAVLIEKVFPIRYTPAGIPVLDIILKHESWQEENGQ
                     QCLVQLEIPARILGRQAEEWQYRQGVYVHVEGFLAQKSRRSLMPMLRIQNIQEYKG"
     gene            6104..6334
                     /gene="rpsR"
                     /locus_tag="ACFOAE_000006"
     CDS             6104..6334
                     /gene="rpsR"
                     /locus_tag="ACFOAE_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009120066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFC6883589.1"
                     /translation="MARQSFKRRKFCRFTAEKIQEVDYKQVDLLKDFISENGKIIPAR
                     ITGTKAFYQRQLAVAVKRARFLALLPYTDQHK"
     gene            6351..6803
                     /gene="rplI"
                     /locus_tag="ACFOAE_000007"
     CDS             6351..6803
                     /gene="rplI"
                     /locus_tag="ACFOAE_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFC6883590.1"
                     /translation="MQIILLEKIGGLGNLGDIVTVKNGYARNFLIPAGKAKRATEANM
                     KEFEARRAELEAKQAEILADARVRQEKLDGQTITVAQKAGVDGRLFGSVTNADIAAAI
                     VAAGIEAVKANVRLPNGPLKAVGEYEVEVALHTDAVAKITVAVVAATE"
     gene            6817..6924
                     /locus_tag="ACFOAE_000008"
     CDS             6817..6924
                     /locus_tag="ACFOAE_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HFC6883591.1"
                     /translation="MPSETLPIVGMWFQTVFVLFSVYSAKIGMVVFIVD"
     gene            7526..7753
                     /locus_tag="ACFOAE_000009"
     CDS             7526..7753
                     /locus_tag="ACFOAE_000009"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883592.1"
                     /translation="MGGSRIAWNQHGSRISWNRHGRRCADAFGREGGAIGSLEKGNGI
                     CGQKKLRVKVGRTVRLSVLLSEQEAGQLCPD"
     gene            complement(7781..8587)
                     /locus_tag="ACFOAE_000010"
     CDS             complement(7781..8587)
                     /locus_tag="ACFOAE_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC6883593.1"
                     /translation="MWHWDIILILLAVGSAAGFIAGLFGVGGGTLIVPVVLWVLDLQG
                     LAQHPYAQHLAVGTSFAVMVFTAFSSMLGQHKKQAVDWKTVFTMMPGMVFGVFAGALS
                     AKYIPAFGLQIFFILFLTAVAFKTLHTGPQTASRPLPGLPGLTAVSTLFGAMSSWVGI
                     GGGSLSVPFLIHCGFPAHKAIGTSSGLAWPIALSGAISYLLNGLNIAGLPEGSLGFLY
                     LPAVAVLSAATIAFAPLGVKTAHKLSSAKLKKSFGIMLLLIAGKMLYNLL"
     gene            complement(8588..9334)
                     /gene="pssA"
                     /locus_tag="ACFOAE_000011"
     CDS             complement(8588..9334)
                     /gene="pssA"
                     /locus_tag="ACFOAE_000011"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003882 - CDP-diacylglycerol-serine
                     O-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HFC6883594.1"
                     /translation="METPTNTPQRSLRQNSIYLLPNSFTIAALFSAFYAITQSMHGRY
                     ETAAIAVFISMLLDGMDGRVARLTNSQSAFGEQLDSLADMVSFGVAPALIAYKWQLWQ
                     FGKIGYSVAFIYCACAALRLALFNTLIGKVDKRWFIGVPSPTAAALIVGLIWVNHSVE
                     KFPAVHWWALGITLFAGLSMIVQIPFWSFKEINIRRQVPFVGMLLAVLLLLLVTWEPS
                     LVLFLFFLGYSLSGYIMAARRFWKKYRKAD"
     gene            9917..10398
                     /locus_tag="ACFOAE_000012"
                     /pseudo
     CDS             9917..10398
                     /locus_tag="ACFOAE_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245995.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4189 domain-containing protein"
     gene            complement(10450..11661)
                     /locus_tag="ACFOAE_000013"
     CDS             complement(10450..11661)
                     /locus_tag="ACFOAE_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease family protein"
                     /protein_id="HFC6883595.1"
                     /translation="MNQLKLAVSGAQILFVAFGAMVLVPLLTGLNPALALLGAGLGTL
                     LFQITTKRKVPIFLGSSFAFIAPIIYSVGEWGLPSTMFGLFAAGFMYFVFAALIRWRG
                     LAAVHKLLPPVVIGPVIMVIGLSVAVAASSMAMGQADGKQVIDYTDSLILSGFTFAVT
                     AIVSVFGSRMMKLIPILIGVASGYVLALLMGLVDTASIAHAPWFAVPHFETPQINWQA
                     ALFMLPVAVAPAIEHIGGIMAIGNVTGKDYTKDPGLDKTLAGDGLGVCVAGLIGGPPV
                     TTYGEVTGAVMITKNSNPVIMTWAAVFAVCMAFFGKFNAFLASIPMPVMGGIMLLLFG
                     TIASLGVKTLIDAKVDLMLPKNLVIVSSVLTTGIGGMTLKLGSFSFAGVGLCAVLAIV
                     LNSLLPDPKES"
     gene            11884..14322
                     /locus_tag="ACFOAE_000014"
     CDS             11884..14322
                     /locus_tag="ACFOAE_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFC6883596.1"
                     /translation="MTEKSHKKTAKGRAGSPSPTSARNKKADNGARGNKVSERLKAVK
                     ELQKTETKKARPEHVVNLIGDALWLMGLAATLYLAISLISFDMGDPSWSHSSPVVEDV
                     ANWGGLFGAYVADVGYYLFGWSFWWWIAAACVMLYKNFRLHAKQTENEAYNHKIAAAA
                     LFVLTVFSPVLEYFVLGGKYADSLPVGAGGMVGIRVGAVFAWLLGKSGSLLIILVVLL
                     LSLSLLVQISWLEFLNGAGRAVQNRLSALSGKVMALGKRRPNSKTDGVDTQNTRRMVK
                     EAKNITAKPVALPEGSSSNRKSVAVSVAPSPKIQVSLFEDDEPRQAGEYHKPTLNLLR
                     IPDSEPVSINPAELERTAELIESKLAEFGIGVQVVSATSGPVITRYEIEPAQGVKGSQ
                     IVALSKDLARSMSLQSVRIVETIAGKNTMGIELPNDKRQDVMLSEILSSPVFAGAKSK
                     LTVALGKDIAGTPVVGDLAKMPHLLVAGMTGSGKSVGVNGMIMSMLFKATPDEVRFIM
                     IDPKMLELSIYDGIPHLLCPVVTDMREAGQALNWCVAEMEKRYRLLSHAGVRNLEGFN
                     QKVEAAKAAGKPLLNPFSLNPDNPEPLEKLPMIVVVIDELADLMMTERKAVEQQIARL
                     AQKARAAGIHMIVATQRPSVDVVTGLIKANIPTRMAFTVQSKIDSRTILDQMGADELL
                     KYGDSLFLQPGSAEPTRLQGAFVSDDEVHQVVNYVKSQAPADYIEGLLSGEAALETAN
                     IVNPNADSDELFDQAVAYVLESKKTSISSLQRQLRIGYNRAANLMEALENAGVVSPTD
                     LNGSRKILAHKDHL"
     gene            14531..15841
                     /gene="tig"
                     /locus_tag="ACFOAE_000015"
     CDS             14531..15841
                     /gene="tig"
                     /locus_tag="ACFOAE_000015"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003742150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFC6883597.1"
                     /translation="MSVTVETLENLERKVVLSLPWSEINAETDKKLKQTQRRAKIDGF
                     RPGKAPLKMIAQMYGASAQNDVINELVQRRFHDVAVAQELKVAGFPRFEGVEEQDDKE
                     SFKVAAIFEVFPEVVIGDLSAQEVEKVTASVGDAEVDQTVEILRKQRTRFNHVEREAR
                     NGDRVIIDFEGKIDGEPFAGGASKNYAFVLGASQMLPEFEAGVVGMKAGESKDVTVNF
                     PEEYHGKDVAGKTAVFTITLNNVSEATLPEVDADFAKALGIADGDVAKMREEVKKNVS
                     REVERRVNEQTKESVMNALLKAVELKVPVALVNEEAARLANEMKQNFVNQGMADAANL
                     DLPLDMFKEQAERRVSLGLILAKLVDENKLEPTEEQIKAVVANFAESYEDPQEVIDWY
                     YAEPSRLQVPTSLAIESNVVDFVLGKAKVNEKALSFDEVMGAQA"
     gene            15937..16551
                     /gene="clpP"
                     /locus_tag="ACFOAE_000016"
     CDS             15937..16551
                     /gene="clpP"
                     /locus_tag="ACFOAE_000016"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFC6883598.1"
                     /translation="MSFDNYLVPTVIEQSGRGERAFDIYSRLLKERIVFLVGPVTDES
                     ANLVVAQLLFLESENPDKDIFFYINSPGGSVTAGMSIYDTMNFIKPDVSTLCLGQAAS
                     MGAFLLSAGEKGKRFALPNSRIMIHQPLISGGLGGQASDIEIHARELLKIKEKLNRLM
                     AKHCGRDLADLERDTDRDNFMSAEEAKEYGLIDQILENRASLQF"
     gene            complement(16608..17873)
                     /gene="ispG"
                     /locus_tag="ACFOAE_000017"
                     /gene_synonym="gcpE"
     CDS             complement(16608..17873)
                     /gene="ispG"
                     /locus_tag="ACFOAE_000017"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HFC6883599.1"
                     /translation="MNTLQRRKTHQVRIDHITVGSEAPVVIQSMTNTDTADAKATALQ
                     IKELSDAGSEMVRITVNSPEAASKVAEIRRRLDDMGYATPLIGDFHFNGERLLAEFPE
                     CGKALSKYRINPGNVGKGVKGDEKFAFMIRTAAENDKAVRIGVNWGSLDQSLAKRMMD
                     ANLASSAPKPPEEVTKEALIVSALESAEKAVLLGLPEDKIILSCKVSAVQDLIQVYRE
                     LGSRCAYPLHLGLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGSPRTQEV
                     VVGQEILQTMGLRSFTPMVTACPGCGRTTSTVFQELAQDVQNYLRQKMSIWRTLYPGV
                     ESLNVAVMGCVVNGPGESKLADIGISLPGTGETPVAPVYVDGERKITLKGDNIATEFL
                     AIVEEYVKTNYGENGSKRNQNKIIPIQSL"
     gene            complement(17889..18650)
                     /gene="pilW"
                     /locus_tag="ACFOAE_000018"
     CDS             complement(17889..18650)
                     /gene="pilW"
                     /locus_tag="ACFOAE_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis/stability protein PilW"
                     /protein_id="HFC6883600.1"
                     /translation="MPFKPSKRISLLLVLALGACSTSYRPSRAEKANQVSNIKTQLAM
                     EYMRGQDYRQATASIEDALKSDPKNELAWLVRAEIYQYLKVNDKAQESFRQALSIKPD
                     SAEINNNYGWFLCGRLNRPAESMAYFDKALADPTYPTPYIANLNKGICSAKQGQFGLA
                     EAYLKRSLAAQPQFPPAFKELARTKMLAGQLGDADYYFKKYQSRVEVLQADDLLLGWK
                     IAKALGNAQAAYEYEAQLQANFPYSEELQTVLIGQ"
     gene            complement(18653..19747)
                     /gene="rlmN"
                     /locus_tag="ACFOAE_000019"
     CDS             complement(18653..19747)
                     /gene="rlmN"
                     /locus_tag="ACFOAE_000019"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFC6883601.1"
                     /translation="MKTNLLNYDLQGLTRHFADMGEKPFRAKQVMRWMHQSGAQNFNE
                     MTDLAKSLRHKLNEQAGIEIPKLMMSQKSSDGTRKWLLDVGTGNGVETVFIPESDRGT
                     LCISSQVGCALECTFCSTGRQGFNRNLTAAEIIGQLWWANKAMGVTPKNERVISNVVM
                     MGMGEPMANFDNVVTALSIMLDDHGYGLSRRRVTVSTSGMVPQMDRLRDVMPVALAVS
                     LHASNDEVRNQIVPLNKKYPLKELMAACQRYLVKAPRDFITFEYVMLDGINDKAQHAR
                     ELIELVKDVPCKFNLIPFNPFPNSGYERSSNENIRVFRDILQQAGFVVTVRKTRGDDI
                     DAACGQLAGQVQDKTRRQQKWQQILIGQQG"
     gene            complement(19890..20315)
                     /gene="ndk"
                     /locus_tag="ACFOAE_000020"
     CDS             complement(19890..20315)
                     /gene="ndk"
                     /locus_tag="ACFOAE_000020"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFC6883602.1"
                     /translation="MAIERTISIIKPDAVGKNVIGKIYSRFEENGLKIVAAKMKQLTL
                     KEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPAEAAEGT
                     IRADFATSVSINAVHGSDSVENAALEIAYFFSQTEICPR"
     gene            complement(20374..21525)
                     /gene="zapE"
                     /locus_tag="ACFOAE_000021"
     CDS             complement(20374..21525)
                     /gene="zapE"
                     /locus_tag="ACFOAE_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HFC6883603.1"
                     /translation="MSNRDQLFKAPPFENHSPLTWYQAASQLPNFIRDDAQAAAIEHL
                     DRLWTELMMFKRKRNRFLGRSLRSPQVPKGLYFYGGVGRGKSFLMDAFFGCLPYRRKR
                     RVHFHAFMAEIHQRLKTLKSESNPLKSVAAEIAKETRVLCFDEFHVSDIADAMILGRL
                     LENLLNEGVVLVATSNYAPSELYPQGQNRSSFLPTIAIIESSLTVLNVDGGEDYRLRT
                     LRPAEIFFTPANEENEAKLAKLFKEMTGITDLNPGISTIHGREIPHKAESGRAIWFDF
                     RALCFGPRSQSDYLYLAEHYEMVFISGLEQLSPQEKAEARRLTWLIDVLYDFRVKLCA
                     TGAVDVNHIYTEGDFAEEFTRTASRMVEMQSEVYLEQPHLTLSPKASGG"
     gene            complement(21916..22743)
                     /gene="fghA"
                     /locus_tag="ACFOAE_000022"
     CDS             complement(21916..22743)
                     /gene="fghA"
                     /locus_tag="ACFOAE_000022"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011961786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018738 - S-formylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0046294 - formaldehyde catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HFC6883604.1"
                     /translation="MKLIEQHQIFGGSQQVWAHHAQTLQCEMKFAVYLPNNPENRPLG
                     VIYWLSGLTCTEQNFITKSGFQRYAAEHQVIVVASDTSPRGEQVPNDDAYDLGQGAGF
                     YLNATEQPWAANYQMYDYILNELPRLIEKHFPTNGKRSIMGHSMGGHGALVLALRNQE
                     RYQSVSAFSPILSPSLVPWGEKAFTAYLGKDREKWQQYDANSLIQQGYKVQGMRIDQG
                     LEDEFLPTQLRTEDFIETCRAANQPVDVRFHKGYDHSYYFIASFIGEHIAYHAAFLK"
     gene            complement(22752..23861)
                     /locus_tag="ACFOAE_000023"
     CDS             complement(22752..23861)
                     /locus_tag="ACFOAE_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0051903 - S-(hydroxymethyl)glutathione
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="HFC6883605.1"
                     /translation="MKSRAAVAFAPNQPLQIVEIDVEMPRKGEVLIRNTHTGVCHTDA
                     FTLSGSDPEGVFPVVLGHEGAGVVVAVGEGVSSVKPGDHVIPLYTAECGECEFCCSGK
                     TNLCVSVRDTQGKGLMPDGTTRFSYQGQPIYHYMGCSTFSEYSVVAEVSLAKINPEAN
                     HEQVCLLGCGVTTGIGAVHNTAKVQEGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPSKFELAKQFGATDCLNPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRQALES
                     AHRGWGQSIIIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSELPKMVEDSMKGD
                     IELEPFVTHTMTLDQINKAFDLMHEGKSIRAVIHY"
     gene            24009..24416
                     /locus_tag="ACFOAE_000024"
     CDS             24009..24416
                     /locus_tag="ACFOAE_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFC6883606.1"
                     /translation="MAYTTAKAAEKIGISAHTLRFYDKEGLLPNIGRDEYGNRCFTDN
                     DLQWLGLLQCLKNTGMSLKDIKRFAECTVIGDDTIEERLSLFENQIENVKCQIAELKR
                     YLDLLEYKLAFYQKAKALGSVKAVNLPQIPETA"
     gene            complement(24767..25081)
                     /locus_tag="ACFOAE_000025"
     CDS             complement(24767..25081)
                     /locus_tag="ACFOAE_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HFC6883607.1"
                     /translation="MTKSELMVRLAEVFAAKNGTHLLAKDVEYSVKVLVDTMTRSLAR
                     GQRIEIRGFGSFDLNHRPARIGRNPKTGERVEVPEKHVPHFKPGKELRERVDLALKEN
                     AN"
     gene            complement(25092..26777)
                     /gene="rpsA"
                     /locus_tag="ACFOAE_000026"
     CDS             complement(25092..26777)
                     /gene="rpsA"
                     /locus_tag="ACFOAE_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFC6883608.1"
                     /translation="MSMENFAQLLEESFTLQEMNPGEVITAEVVAIDQNFVTVNAGLK
                     SESLIDVAEFKNAQGEIEVKVGDFVTVTIESVENGFGETKLSREKAKRAADWIALEEA
                     MENGDILSGVINGKVKGGLTVMINSIRAFLPGSLVDVRPVKDTSHFEGKEIEFKVIKL
                     DKKRNNVVVSRRAVLEATLGEERKALLENLQEGFVIKGIVKNITDYGAFVDLGGIDGL
                     LHITDLAWRRVKHPSEVLEVGQEVEAKVLKFDQDKQRVSLGMKQLGEDPWSGLTRRYP
                     QGTRLFGKVSNLTDYGAFVEIEQGIEGLVHVSEMDWTNKNVHPSKVVQLGDEVEVMIL
                     EIDEGRRRISLGMKQCQANPWEEFAANHNKGDKISGAVKSITDFGVFVGLPGGIDGLV
                     HLSDLSWTESGEEAVRKYKKGEEVEAVVLAIDMEKERISLGIKQLEGDPFGNFISVND
                     KGSLVKGSVKSVDAKGAVIALSDEVEGYLPASEFAADRVEDLTTKLKEGDEVEAVIVT
                     VDRKNRSIKLSVKAKDAKESREALNSVNAAANANAGTTSLGDLLKAKLSGEQE"
     gene            complement(26932..27588)
                     /gene="cmk"
                     /locus_tag="ACFOAE_000027"
     CDS             complement(26932..27588)
                     /gene="cmk"
                     /locus_tag="ACFOAE_000027"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFC6883609.1"
                     /translation="MNRQKVIAIDGPGASGKGTVAARVAAALGYDYLDTGALYRLTAL
                     YAQKQGVGWHDEENVSELAKKLPAVFSDSRILLGGEDVSDGIRTEAIGMGASAVAQLP
                     KVRASLLQRQRDFLTEKGLVADGRDTGSVVFPQAELKIFLTAESKIRAERRAKQIGIP
                     CEGLAFERILSDIEARDEADRNRKVAPLKQQPDALLLDTSRLTIEETVKKVLDWYRKV
                     "
     gene            complement(27684..27818)
                     /locus_tag="ACFOAE_000028"
     CDS             complement(27684..27818)
                     /locus_tag="ACFOAE_000028"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883610.1"
                     /translation="MPSESHTDFRRHYIDARHNTRNAGIRIGLPASVGYFRAGGVPSA
                     "
     gene            complement(27832..29148)
                     /locus_tag="ACFOAE_000029"
                     /pseudo
     CDS             complement(27832..29148)
                     /locus_tag="ACFOAE_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519747.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            29471..29577
                     /locus_tag="ACFOAE_000030"
                     /pseudo
     CDS             29471..29577
                     /locus_tag="ACFOAE_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(29779..30471)
                     /locus_tag="ACFOAE_000031"
     CDS             complement(29779..30471)
                     /locus_tag="ACFOAE_000031"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFC6883611.1"
                     /translation="MKLIKYLQYQGIGSRKQCQWLIAGGYVFINGTCMDDTDADIDSS
                     SVETLDIDGEAVTVVPEPYFYIMLNKPEDYETSHKPKHYRSVFSLFPDNMRNIDMQAV
                     GRLDADTTGVLLITNDGKLNHNLTSPSRKIPKLYEVTLKHPTGETLCETLKNGVLLHD
                     ENETVCAADAVLENPTTLLLTITEGKYHQVKRMIAAAGNRVQHLHRRRFAHLETENLK
                     PGEWKFIECPKF"
     gene            complement(30539..32515)
                     /locus_tag="ACFOAE_000032"
     CDS             complement(30539..32515)
                     /locus_tag="ACFOAE_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFC6883612.1"
                     /translation="MSKLKTIALTASGLSVCPGFLYAQNTSSHQIGLAIMRLNSSILD
                     LPPTKQYFQSGSLWSELRQGFRMGEVNPELVRRHESKFIASHSYFNRVINRSRPYMYH
                     IANEVKKRNMPAEAALLPFIESAFVTKAKSHVGASGLWQFMPATGRHYGLEKTPVYDG
                     RHDVYAATDAALNYLQYLYGLFGDWPLAFAAYNWGEGNVGRAINRARAQGLEPTYENL
                     RMPNETRNYVPKLLAVRNIIATPQSFGMNISDIDNKPYFQAVEPDRPLDNEAIARLAG
                     ITQSELLALNPAFNVPAFIPKSKRKLLLPVASVQTFQSNYLNAAPDSLFSWEVYTPAA
                     KTSLSDISTATGMSIADIKRLNNLNGNLVNAGRSILVAKNGKTLQTASESVVSIDIDN
                     TPDTYRSNMPAGTVNVGIARIRPAAAQTADITVAPLPQKTVRTEPDPLVRIAEPALAT
                     AAAQPQTEKQTAMPSETQTATLAQIIPQNDMQAADELMQLVARNNLRRQAEETISAVI
                     GTPDTVAEHKISASPQHTAAADGKRRIRLETRIAKAADGEAEISPLHASIHRVVEGDT
                     LFNIAKRYNVSVADLIVANNIKGNTIQKGQVLRLEQAAPAQTRIEKVSYTARKGDTFK
                     SIAARFNIHIDDIRRLNPNLNTINPGQRVKLIGS"
     gene            32694..33359
                     /locus_tag="ACFOAE_000033"
     CDS             32694..33359
                     /locus_tag="ACFOAE_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFC6883613.1"
                     /translation="MDSWFEDTAMGRYVAKLEQDFFGRYLDSYRFSGMCAVQVGGPWL
                     SLSEDVVCVPRDMSMSAENMALADVSADMLLFPHTLEGGVPSQILSEAHRILKPSGRL
                     MLTGFNPYSLWGFSRWFDGERLPEKRFCLPLPELKRRLADVGFDIEFGKFMVYLPPVS
                     SLGQIRFWRFMEKAGDRWWPQCAAVYGLVLVKRAAGVTPLPAWDGYLGGKALAAGAAR
                     VAD"
     gene            33411..34238
                     /gene="mutM"
                     /locus_tag="ACFOAE_000034"
     CDS             33411..34238
                     /gene="mutM"
                     /locus_tag="ACFOAE_000034"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFC6883614.1"
                     /translation="MPELPEVETTLRGIAPHIEGKTVEAVVLRQLKLRWQINPDLGEI
                     LSGRQVLSCGRRAKYLIVRFQTGILLIHLGMSGSLRIFTPSDGRIGRPDRHDHVDIVF
                     SDGTVMRYRDPRKFGAILWYEGIEEHHPLLEKLGPEPLSEAFCADYLYERLKAQKRAV
                     KLALMDNAVVVGVGNIYANESLFRAGISPHRPANRLKKKECALLVETVKAVLRRAIET
                     GGSTLRDFVDSDGKSGYFQQEYTVYGRHNQPCPRCGGLVVKETLGQRGTFYCPNCQK"
     gene            34326..35093
                     /locus_tag="ACFOAE_000035"
     CDS             34326..35093
                     /locus_tag="ACFOAE_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HFC6883615.1"
                     /translation="MSSNKASFFTRLRRLCRLTVWLFKTGKNLRGIDGGCPESRNRAV
                     IELGRGALAALDIGLEVGRPAPEHPNGVLVAANHVSWLDIFAMSAVYPSSFIAKQEIK
                     SWPVLGKMGQNAGTVFINRNSRRDIEPINRAVCETLQRGQNVSFFPEARTSSGLGILP
                     FKAALFQSAIDAGAKVLAVALRYYDETGKRTARPSYADVGLPTCLWRIVSMKKLTIKV
                     DFVCVADAAESEDRYALKDKIEESIRAVVADDADIAV"
     gene            complement(35404..35715)
                     /locus_tag="ACFOAE_000036"
     CDS             complement(35404..35715)
                     /locus_tag="ACFOAE_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein"
                     /protein_id="HFC6883616.1"
                     /translation="MLAILLSAILGLVSTTAAAGTSEPAHRHTKHIRKANKQMLHPEC
                     RKYLERRAAWYRSQGNVQELRENKKARKAFRSLPYKEQKTQCQAAYEAFDDFDGSRFR
                     R"
     gene            36244..38523
                     /gene="nrdA"
                     /locus_tag="ACFOAE_000037"
     CDS             36244..38523
                     /gene="nrdA"
                     /locus_tag="ACFOAE_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1a ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFC6883617.1"
                     /translation="MNTPTDLKVTKRDGRLEAIDLDKIHRVVTWAADGLENVSVSQVE
                     LKSHIQFYNGIRTDDIHETIIKAAADLISEDTPDYQYLAARLAIFHLRKIAYGEYEPP
                     HLYDHVKKLTDAGKYDRHILEDYSREEFDELNAYIDHERDMSFSYAAVKQLEGKYLVQ
                     NRVTRQIYETPQFLYVLVAMCLFSKYPKETRLDYVKRFYDAVSTFKVSLPTPIMSGVR
                     TPTRQFSSCVLIECDDSLDSINATTSAIVKYVSQRAGIGINAGRIRGLDSEIRGGEAR
                     HTGCIPFFKMFQAAVKSCSQGGVRGGAATLFYPLWHIEAESLLVLKNNRGVEDNRIRQ
                     LDYGVQINRLLYTRLIKGGNITLFSPNEVPGLYEAFFADQDEFERLYTKYEQDPDIRK
                     RIIPAADLFSTLMQERAGTGRIYIQNVDHCNTHSPFDPRVAPVHQSNLCMEIALPTKP
                     LDNINDPNGEIALCTLSAFNLGALNSLDELEGLADLTVRALDALLDYQGYPVEAARTS
                     TMGRRSLGIGVINYAYYLAKNGVRYSDGSALGLTHRTFEAIQYYLLKASANLAKEYGA
                     CTLFNQTVYSQGKLPIDTYKKDLDAVCNEPLHYDWESLRADIVKYGLRNSTLTALMPS
                     ETSSQIANATNGIEPPRGLVTVKASKDGILKQVVPEFETLKNAYETLWQLPGNEGYLK
                     LVGVMQKFVDQAISANTAYDPGKFEGGKVSMKQMLKDLLTAYKYGVKTLYYHNTRDGA
                     DDTQTDIQDDGCAGGACKI"
     gene            38581..39594
                     /gene="dcm"
                     /locus_tag="ACFOAE_000038"
     CDS             38581..39594
                     /gene="dcm"
                     /locus_tag="ACFOAE_000038"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFC6883618.1"
                     /translation="MKNKIQNQLDNIVTLNNEKFTFIDLFAGIGGFRIAMENVGGRCV
                     FSSEWDDKARQTYQVNFNDIPYGDITLKETKAAIPSKFDVLTAGFPCQPFSIAGVSKK
                     KSLGRETGFLDKAQGTLFFDVAEIIGKHRPKIFLLENVKNLVSHDKGNTFKVIKGTLE
                     ELDYQIFYQVMNAKYYVPQNRERIFIVGFDRQYFNKEINFNFPSPPESQPKLKQILED
                     DVDNSFTLSDNLWLYLQNYAKKHKAKGNGFGFGLVDLDGISRTLSARYYKDGSEILIP
                     QKGKNPRKLTPRECSRLMGFPKDFVIDAVSKTAAYKQFGNSIAVPLVQAIAKQIINEL
                     KNE"
     gene            39587..40774
                     /locus_tag="ACFOAE_000039"
     CDS             39587..40774
                     /locus_tag="ACFOAE_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HFC6883619.1"
                     /translation="MNDLAAQTIQVVNKSDDLVASAIQTANKSIAVYCRYIRPNDVGT
                     TGSHQSGFYIQKHFSDDLFDVVCQKGTNKTISIKINWQDGSVTNSNFKYYGQGTRNEA
                     RITGFGKNFEFLSDKYSGSLLVLCRACYKDLLFHAFVLSSDEDIEIFIAETNILPGSL
                     YLPKKQEVEDNLTKLFSLFPNFPKTEEMAVLARENIALNKTNVSNVLKQWVSKEYELF
                     SIFEKREFEIIKSKITDLDSFINFAHSFTNRRKARAGKSLELHLSRIFDEFSLKFETQ
                     AKTEGKKKPDFLFPGSEEYHAMDESGNFIFQTEKLTMLGSKTTCKDRWRQVLNEADRI
                     PHKHLFTLQEGISDTQIQEMSDENLTLVVPKESVKTFGTFGKTHVLTLENFIKYIKSQ
                     QVS"
     gene            40835..41968
                     /gene="nrdB"
                     /locus_tag="ACFOAE_000040"
     CDS             40835..41968
                     /gene="nrdB"
                     /locus_tag="ACFOAE_000040"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ia ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFC6883620.1"
                     /translation="MSYSTFPKTKNDALNEPMFFGQPVNVARYDQQKYEVFEKLIEKQ
                     LSFFWRPEEIDVSRDRIDYANLPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSI
                     PELETWIETWSFSETIHSRSYTHIIRNIVNDPSVVFDDIVENEYITARAEDIACYYDD
                     LIEYTQYYNLLGEGVHNVGGKPITVSLRGLKKKLYLCLMCVNVLEAIRFYVSFACSFA
                     FAERELMEGNAKIIKLIARDEALHLTGTQHMLNLMRSGVDDSEMAEIAAELQDECFQL
                     FKKAAEQEKEWAAYLFKDGSMIGLNKEILSQYVEYITNLRMQAVGLPAGFEGANQNPI
                     PWINAWLSSDNVQVAPQEVEISSYLIGQIDSEVNTDDLGDFEL"
     gene            42166..42456
                     /gene="yfaE"
                     /locus_tag="ACFOAE_000041"
     CDS             42166..42456
                     /gene="yfaE"
                     /locus_tag="ACFOAE_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I ribonucleotide reductase maintenance
                     protein YfaE"
                     /protein_id="HFC6883621.1"
                     /translation="MARIGTNKGFFELLEGETLLEGLERTGHMVEYQCRSGYCGSCRV
                     KILEGSVTYREPPLAFLGRDEILPCCCYVEGDVRLDCGLSGEDEGLSDSLLK"
     gene            complement(42497..42775)
                     /gene="ftsB"
                     /locus_tag="ACFOAE_000042"
     CDS             complement(42497..42775)
                     /gene="ftsB"
                     /locus_tag="ACFOAE_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HFC6883622.1"
                     /translation="MKWVTVVLSFALVCCQYSLWFGKGSIGRNSSLREQIAVQEEKNQ
                     TLALRNHSLAAEVYDLENGQEAISEIARVELGYIQDGETFYRLIRHNR"
     gene            complement(42790..44076)
                     /gene="eno"
                     /locus_tag="ACFOAE_000043"
     CDS             complement(42790..44076)
                     /gene="eno"
                     /locus_tag="ACFOAE_000043"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFC6883623.1"
                     /translation="MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTG
                     QKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTEN
                     KGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSL
                     NIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEA
                     LQLMVEATEAAGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLEGLV
                     NEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKILAEGIEKGVANAL
                     LVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSL
                     SRSDRMAKYNQLLRIEEELAEAADYPSKAAFYQLGK"
     gene            complement(44123..44563)
                     /locus_tag="ACFOAE_000044"
     CDS             complement(44123..44563)
                     /locus_tag="ACFOAE_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4149 domain-containing protein"
                     /protein_id="HFC6883624.1"
                     /translation="MMQTFRKISRYAATLWLGMQIMAGYIVAPVLFKMLPKMQAGEIA
                     GVLFDILSWSGLAVWGAVLAAAFAALTRRQTALLLFLLSALAANRFLITPVIEALKYG
                     HENWLLSFVGGSFGMWHGISSIVFMATALLSAVLSWRLSGKDAV"
     gene            complement(44578..45420)
                     /gene="kdsA"
                     /locus_tag="ACFOAE_000045"
     CDS             complement(44578..45420)
                     /gene="kdsA"
                     /locus_tag="ACFOAE_000045"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008676 - 3-deoxy-8-phosphooctulonate
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HFC6883625.1"
                     /translation="MDIKINDITIGNNSPFVLFGGINVLESLDSTLQTCAHYVEVTRK
                     LGIPYIFKASFDKANRSSIHSYRGVGLEEGLKIFEKVKAEFGIPVITDVHEPHQCQPV
                     AEVCDVIQLPAFLARQTDLVVAMAKTGNVVNIKKPQFLSPSQMKNIVEKFHEAGNGKL
                     ILCERGSSFGYDNLVVDMLGFCVMKQTCGNLPVIFDVTHSLQTRDAGSAASGGRRAQA
                     LDLALAGMATRLAGLFLESHPDPKLAKCDGPSALPLHLLEDFLIRIKALDDLIKSQPI
                     LTIE"
     gene            complement(45442..45825)
                     /gene="panD"
                     /locus_tag="ACFOAE_000046"
     CDS             complement(45442..45825)
                     /gene="panD"
                     /locus_tag="ACFOAE_000046"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HFC6883626.1"
                     /translation="MFRTMLGGKIHRATVTEADLNYVGSITVDQDLLDAAGIYPNEKV
                     AIVNNNNGERFETYTISGKRGSGVICLNGAAARLVQKGDIVIIMSYVQLSEPEIAAHE
                     PKVVLVDGNNKIRDIISYEPPHTVL"
     gene            complement(45974..>48101)
                     /gene="mfd"
                     /locus_tag="ACFOAE_000047"
     CDS             complement(45974..>48101)
                     /gene="mfd"
                     /locus_tag="ACFOAE_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFC6883627.1"
                     /translation="AIAVITESDLYQYVARSRKYHRKKHAAVSDGLLRDLAEINIGDP
                     VVHEEHGIGRYMGLVTMDLGGETNEMMLLEYAGEAQLYVPVSQLHLISRYSGQAHENI
                     ALHKLGSGAWNKAKRKAAEKARDTAAELLNLYAQRAAQSGHKFEINELDYQAFADGFG
                     YEETEDQAAAIAAVIKDLTQAKPMDRLVCGDVGFGKTEVALRAAFVAVMGGKQVAVLA
                     PTTLLVEQHAQNFADRFADFPVKVAGLSRFNNSKATKAALEGMADGTVDIIIGTHKLV
                     QDDIKFKNLGLVIIDEEHRFGVRQKEQLKRLRANVDILTMTATPIPRTLSMALEGLRD
                     FSLITTAPSRRLAVKTFVKPFSEGSVREAVLRELKRGGQVFFLHNEVDTIENMRERLE
                     TLLPEARIGVAHGQLRERELEQVMRDFLQQRFNVLLCSTIIETGIDIPNANTIIINRA
                     DKFGLAQLHQLRGRVGRSHHQAYAYLLTPEYITKDAEKRLDAIAAADELGAGFTLAMQ
                     DLEIRGAGEILGEGQSGEMIQVGFTLYTEMLKQAVRDLKKGRQPDLDAPLGITTEIKL
                     HSPALLPESYCPDIHERLVLYKRLAVCETVQQINAIHEELVDRFGLPEQPVKTLIESH
                     HLRLAAKELGIDAIDATGESVTVTFGKNHNVDPTEIILLIQNDKKYRLAGADKLRFTA
                     EMENIEVRINTVKNVLKTLQNRCLPK"
BASE COUNT        11570 a        11335 c        12957 g        12239 t
ORIGIN      
        1 aatttaatcc actatatatc ggtataccga cctactgtat catatttttt acagacggtt
       61 tttgctttgg cggcatacta atgcagatga ttgtaaatgg tttccgccaa tgccttgctg
      121 atgccttcca cttgttccaa atcctcgcgg ctggcggcaa tcacgccgcg caggccgccg
      181 aagcgggtga gcagggcttg gcggcgtttg ctgccgatac cggggatttc gctgagtgag
      241 gaagtaacgc gtgctttgtc gcgttttttg cgatggcctg taatcgcaaa gcggtgcgat
      301 tcatcgcgta cggtttgcaa taaatgcaag gccgggctgt tgggtggcag gcggaagact
      361 tcgccggtaa aaggcagtat aagttcttcc ataccggctt tgcgctcagg gcctttggcg
      421 ataccgacca aaggaatgtg cagcccgagt tcttcccata ctgatacggc tacgccgatt
      481 tgccctttgc cgccgtctat caacacgaca tccggccatt tgacggtctc gccgttggct
      541 tcggcttcct gcattttgcc gtaacggcgc gtcaacactt cgcgcatggc ggcgtagtcg
      601 tcgccgggtt tggcggtcgt gatgttgtag cggcggtatt gcgagggctg gatgttttgc
      661 tcatcgtaca cgacgcagga ggcgatggtg gcttcgcctt gggtgtggct gatgtcgaaa
      721 cattcgaggc ggttgaggcc gtctgaatcc ataccgagga ttttggcgag ttcgtcgatg
      781 cggtgttgct ggctgctttg ttgcaggcgg cgttgtgcaa tcgccatttg tgcgttttgc
      841 tccgccattt tcaaccaaac tttgcgttcg cctatggtct tggtgacaaa ttgcatttgt
      901 ttgccgtgtt cgctctctag ggcttctttc aatgcgtcgg gcatggggaa gttgctgatg
      961 atgatgtcag gtttgctttt gcccagatag tgttgggcga cgaaggcttc ggcatagtct
     1021 tgcccgtttg gctcgggatc gtttttggtg tcggggaaga aacttttgtc tccgacgtgc
     1081 cgcccaccgc gtatgctgac ccagtgtacg cagacgatgc cgtctgaaac cgccagcgcg
     1141 agcaaatcga tatcgttggg gttgttcggg tttttgctgt cgatgaactg gttgctctgc
     1201 atgatgccaa gtgcttgaat ttgatcgcgg taacgtgcgg cttcttcaaa ttgcagattc
     1261 gcggcggcag tttgcatttt gtgttgcagg gtgcgggtca gttcgtcggt tttgccgttg
     1321 agaaaagtgg cggcttgacg cacgctgtcg cggtagtctt cttcgctgat gtgtccgacg
     1381 cagggcgcgg tgcagcgttt gatttggtac agcaggcaag ggcggtcacg atgctcgaat
     1441 acgctgtctt cgcaggtgcg cagcatgaag actttttgca ggacttggat gctgtcgcgc
     1501 acggcgttgc tgttgggata ggggccgaag tattggttcg gctttttcag tgtgccacgg
     1561 taatacgcca tctgcggata ttgatgtccg ctgagcatga ggtagggata gcttttgtcg
     1621 tcgcggaaaa ggatattgta tttcggcgac aaggctttga tgaggttgtt ttcgagaatc
     1681 agggcttcgg cttcggaacg cgtgatggtg gtttcgatat gatgaacctg ttttaccatc
     1741 aatgcgatgc gcggcgaatg gtcgtttttt tggaaatagc cggacacgcg ccgcttgagg
     1801 ttgaccgctt tgccgacgta taagactttg ccgccttcgt caaaaaaacg gtacacgccc
     1861 ggcagcttgg gcaggttttt gaggaagagc gggatgtcga attgttccgg agaacggttt
     1921 tctgtattca tatcaattat ttgaaaaacg gcttcagacg gcatatcggc agcggcagcc
     1981 ttatccgttc ggaaaagctg tcgggtggtt atatgcggtc aatcgatttt tacccgtttc
     2041 aggcgcaagg cgttgctcaa cacggaaacc gagcttgccg ccattgccgc gcctgcgatg
     2101 acagggttta aaaaaccgag cgcggcaagc ggaatgccca aaatattgta gaagaaggcg
     2161 aaaaacaggt tttgcttgat gtttctcaac gtcgcccgcg ataccgatag ggcatcggcg
     2221 agttggttga ccgaatgttg catcagcgtg gcggatgcgg tgtgttcggc aacgtccgcg
     2281 ccgcctttca tggcgaagct aacgttggcg gcggcgagcg caggtgcgtc gttgatgccg
     2341 tctccgacca tcgccacggt tttgccggcg gctttgagtt tctgcacttc ggcggctttg
     2401 tcgcgcggac tcatattacc gaaggcgtgt gcgatgccca gttgtttggc gacgtattcg
     2461 accgtgcctt ggttgtcgcc gctcataata tagacatcga tattgtgttt tttcagacgg
     2521 cctatggctt cggcggtatc ggctttcaac gcgtcggcaa gtgcgaatgc gccgatgggt
     2581 ttgttatcga ctgagaccgc aacaatgctt gcaatatccc aaacgccgtc tgaaaacttc
     2641 ggcaaggcca gttcggcaaa ttcggctttg cctgctttca ccaaacccac gccttccact
     2701 tcggcggtaa tgcctgcgcc gacaacggtt tgggcgtttt gtgcggaagg aatctccaaa
     2761 ccgcgcgctt gggcggcgga gacgatggca cgggcgagcg gatgggcggc gttttgttcg
     2821 acggcggcgg cgatgcggta caaagcgtct tcgtcaaagc cgctgtcggg aacgcaataa
     2881 acggcggcaa cctgcgggct gccttcggtc agcgtgccgg ttttgtccaa cacgacggca
     2941 tcgacgtggg cggcttcctc cattgctgcc gcgtctttaa accaaatacc gtgtttaacc
     3001 gctttgccca taccgaccat aatcgcggca ggggttgcca gacccagcgc gcacgggcag
     3061 gcaatcacca aaacggcaac ggcgtgcatc aatgcgagcg tccaatcgcc cttaatcagc
     3121 caagtagcga taaaagtcaa aagcgcgatg cccacgacag tcggcacgaa cgccgccgcc
     3181 gccttgtccg ccacacgcgc aatcggtgct ttactgcctt gtgcttcaga gagcgcgttc
     3241 atcatgtcgc cgagctgggt ttggctgccg agctgcgtgt cgcggtacac cacactgcct
     3301 tcggtcatta acgcgcccgc caacactttg ccgcccgcct ttttttcttc aggattggat
     3361 tcgccggtaa gatggctctc gtccgcccaa ccgctgccgc tttcaatgat gccgtctgcg
     3421 gcaatgcgtt cgccgtggtt ggcgcggata aggtcgccga tttgcacttg gtcgatggga
     3481 agctgtttcc attcgccgtt gcgttgcacg ttgacttggg ttggtgtaag tttgagcagc
     3541 aagcccaagc tgttgaggct ggattttttg gtacggtgtt ccaaaaattt acccagtgac
     3601 acaaaaccga tcaccatcac gcccacttca aaatacacat gcgccatacc gtacgccgcg
     3661 tgcgggctga aaaacagcat atagacggaa tacaggtaaa tcgagaccgt gccgatggta
     3721 accagcacgt ccatattcgc cagtccgccc ttaatgctcg cccacgcgct tttgtaaaac
     3781 gggattgcca gccaaagctg caccacgctt gccaatgcga actgccacaa cggcggaatc
     3841 atccaatcgt gtctgccgat catcatcccc gccatgccga taaggaacgg gacgttgatg
     3901 gtgaacagca gccacagccg ccagccgata tggtgttctg cttcgggttg cggcaatgta
     3961 tcttccgttt tttccttcgc gccgtaaccg gttttctcaa tgattttggc aatgtcggct
     4021 actgaggttt tgctgtcgtc aaacactacc tgcgcctctt cgctggcgaa gtttaccccc
     4081 gccgattcga caaaatcttt tttgttcaac actttttcaa tgcgcgaagc gcaggcctgg
     4141 caggtcatgc cttcgatttg gaaacggatt ttttgttgca taagcgtgat tcctgctttg
     4201 atattcagac ggcagttaag gctgcgggat gccgtctgag cgccggtatg gtcgaaattt
     4261 ctcaaacgcg ccgataattc gagtagaatc cgaaaacttg acacagcaaa ggaaaaacaa
     4321 tgtcccaaca ccgcaaactg attattttgg gttccggccc cgccggatac accgccgccg
     4381 tctatgccgc gcgcgccaat ttaaaccccg tcattattac aggtatcgcg caaggcgggc
     4441 aactgatgac caccaccgaa gtggacaact ggcctgccga tgccgacggc gtgcaagggc
     4501 cggaattgat ggcgcggttt ctcgcccacg ccgaacgttt cggaacggaa atcatttttg
     4561 accaaatcaa cgccgtcgat ctgcaaaaac gcccgtttac gctcaaaggc gatatgggcg
     4621 agtacacttg cgatgccctg attgtcgcaa caggcgcgtc cgccaaatac ctcggtttgc
     4681 cgagtgagga agcgtttgca ggaaaaggcg tttccgcttg tgccacctgc gacggtttct
     4741 tctataaaaa ccaagatgtt gccgtagttg gcggcggcaa tacggcagtt gaagaggcac
     4801 tctaccttgc caatatcgcc aaaaccgtta ccctgatcca ccgccgcagc gagttccgtg
     4861 ccgaaaaaat catgatcgac aaactgatga aacgcgtgga agagggcaaa atcatcctca
     4921 agctggaaag caacctgcaa gaagtactgg gcgacgatcg gggcgtaaac ggcgcattat
     4981 taaaaaacaa cgacggttct gagcaacaaa ttgccgtcag cggcattttt atcgccatcg
     5041 ggcacaagcc gaataccgat attttcaaag gtcagttgga aatggacgaa gccggctacc
     5101 tgaaaaccaa aggcggcacg gcggacaatg tcggtgcaac caatatcgaa ggcgtatggg
     5161 cggcgggcga cgtaaaagac catacctacc gtcaggcaat taccagcgcg gcttccggct
     5221 gtcaggcggc tttggacgcg gaacgctggc tgggcagcca aaacatttga atgccgtctg
     5281 aaaccgaaat tttcggcgga atgcaaattt ttcgcaccaa atccttgatt ccgtcggcaa
     5341 accccaatat aatgcctgct ctttgaacct tgccttctgc tttcgcatgg cagaaggctg
     5401 tttttaccat ccataaggag ataacatgcg tcattacgag atcgtgttta tcgttcatcc
     5461 tgatcaaagc gagcaagtgc ctgctatggt tgaacgttac aaaaccatga ttgccgaagc
     5521 aaacggtaag attcaccgtt tggaagattg gggtcgccgc caactggctt acccgattaa
     5581 caaaatccat aaagcccatt acgttttgat gaacatcgaa accactcccg aagtggttga
     5641 agagctggaa accgcattcc gcttcaatga tgccgtattg cgccatctaa ccatcaaaac
     5701 caaacacgcc gttaccgaag catcccctat gttgggtggt gaaaaggcta agaacctgtt
     5761 gagcggcgcg tctgaagaag cggtcgccca ataattggga ttcaataatc ttgtttcgct
     5821 tgccgtgtta attgaaaagg ttttccctat tcgatatacg cctgccggaa tccctgtttt
     5881 agatattatt ttaaagcacg aatcgtggca ggaggaaaac gggcagcaat gccttgtcca
     5941 attggaaatt ccggcacgga ttttaggcag gcaggcggaa gagtggcagt atcggcaagg
     6001 tgtatatgtt cacgtcgaag gttttttagc tcaaaaaagc agacgttccc ttatgccgat
     6061 gctcaggata caaaatattc aagaatataa aggttaaacg acaatggctc gtcaatcatt
     6121 caaacgtaga aaattctgcc gtttcacggc tgaaaaaatc caagaagtcg attacaaaca
     6181 agttgatttg ctgaaagact ttatctctga aaacggtaaa atcattcctg cacgcatcac
     6241 aggaacgaag gcattctacc aacgccaatt ggctgttgcc gtaaaacgcg cacgcttcct
     6301 ggctctgctg ccttacaccg accaacacaa ataattttgg agattgaatc atgcaaatta
     6361 ttctgttaga aaaaatcggc ggtctgggca acttgggcga catcgtaacc gttaaaaacg
     6421 gctacgcccg caactttcta attcccgcag gtaaggcaaa acgtgcgacc gaagcgaata
     6481 tgaaagagtt tgaagcacgc cgtgccgaat tggaagccaa acaggctgaa attttggcag
     6541 atgcccgagt ccgtcaggaa aaattggacg gtcaaaccat taccgttgca caaaaagccg
     6601 gtgtggacgg tcgcctgttc ggttccgtca ccaatgctga tattgcggct gcaatcgttg
     6661 ctgccggcat cgaagccgtg aaagcaaatg tacgtctgcc gaacggtcct ctgaaagccg
     6721 ttggcgagta cgaagtggaa gtggctttgc acactgatgc cgttgctaaa attaccgttg
     6781 ccgtcgttgc cgcaaccgag taattgaaat tatcagatgc cgtctgaaac cctgccgatt
     6841 gtcggaatgt ggtttcagac ggtatttgtt ttgttttccg tatattctgc aaaaatcggg
     6901 atggttgttt ttatagtgga ttaaatttaa accagtacag cgttgcctcg ccttgccgtg
     6961 ctatctgtat tgtctgcggc ttcgtcgcct tgtcctgatt tttgttaatc cactatattt
     7021 gcctgtggtc tttgcaggaa tagtttgtta acgaaatttg atgcataaaa tgcgccaaaa
     7081 aatattggct gtgttttaat atagtgttga taagcgtacc tggcttcaat atactcaata
     7141 ggataggtct cttcctaacc gaaaaaataa ttgtcttttc ccttgcaaat aattgaaatc
     7201 aacagattac taaaacacag ccaaaatatt caattgacaa aaacttttct gattttgaga
     7261 aatctgtgaa aatcagggga ttatttattt tgaaaatggt atcgggcata aaatttggct
     7321 gtgtttcaat atggtgctga taacatactt tgtttcaaaa tgttcaatag gataacttcc
     7381 tgattgaccg aaaaataatg gccttttccc ttgcaagcag ttgaaatcaa cagattgtca
     7441 aaatacatcc taaaaattta ataacttata tatatgattg caaaggttgc ggcttgtatg
     7501 ccggtcatta tggcggaaat accgtttggg aggcagccgc atcgcgtgga atcagcacgg
     7561 cagccgcatc tcgtggaatc ggcacggcag gcgatgcgcc gatgccttcg ggcgtgaagg
     7621 cggggcaatc ggcagtttgg aaaaaggcaa tggaatctgt gggcagaaga agttaagggt
     7681 aaaagtcggg cgcacggtca ggttgtctgt ccttttgtcg gaacaggagg cagggcagct
     7741 ttgtcctgat taattgcttg tgcaaacggt aagaaggttt ttaaagcagg ttgtacagca
     7801 tttttccggc aatcaaaagc aacataatgc cgaaggattt tttgagtttg gcagaagaaa
     7861 gtttgtgggc ggttttgaca ccgagcgggg caaaggcaat agttgccgcg ctgaggacgg
     7921 cgacggcggg caggtaaagg aagcccagtg acccttcggg caatcctgca atattcaggc
     7981 cgttgagcag atacgatatt gcgccggaga gtgcaatcgg ccaggcaagg ccggatgatg
     8041 tgccgatggc tttatgggcg gggaagccgc agtggattaa gaaggggacg gaaagtgaac
     8101 cgccgcctat gccgacccag ctcgacattg cgccgaacag tgtggaaacc gcagtcagtc
     8161 cgggcagtcc gggcagcggg cgggatgccg tctgagggcc ggtatgcagt gttttgaatg
     8221 cgacggcggt taaaaacagg atgaagaaaa tttgaagccc gaacgctggg atatattttg
     8281 cggagagtgc gccagcgaat acgccgaata ccatacccgg catcatcgta aatacggttt
     8341 tccagtcgac cgcctgtttt ttgtgctgcc ccagcatact ggaaaaggcg gtgaagacca
     8401 tgacggcgaa ggatgtgccg acggcgaggt gttgcgcgta aggatgttgt gccaaaccct
     8461 gcaaatcaag tacccataaa acgacaggga caatcagcgt gccgccgcct acgccgaaca
     8521 gaccggcaat aaaacctgcc gcactgccta cggcaagcag gattaagata atgtcccaat
     8581 gccacattta atccgccttt ctgtattttt tccagaatcg gcgtgccgcc ataatgtagc
     8641 cggacaggct gtatccgaga aagaacagga agaggacgag cgacggttcc caagtgacca
     8701 gaagcagcaa taagacggca agcagcattc cgacaaaggg gacttgtctg cggatgttga
     8761 tttctttaaa actccaaaaa gggatttgga caatcatcga caggccggca aacagtgtga
     8821 tgcccaatgc ccaccagtgg acggcgggga atttttcgac gctgtggttg acccaaatca
     8881 gcccgacaat cagcgcggcg gcagtcggac tgggcacgcc gataaaccag cgtttgtcca
     8941 ccttgccgat gagcgtgttg aacagggcga ggcgcagggc ggcgcaggcg cagtagatga
     9001 aggcgacgga ataaccgatt ttgccgaact gccaaagctg ccatttgtag gcaataagcg
     9061 cgggggcaac gccgaagctg accatatcgg caaggctgtc gagctgttcc ccgaacgcgc
     9121 tttggctgtt ggtcagccgc gccacgcgcc cgtccatacc gtccagcaac atagagatga
     9181 ataccgcgat ggcggcggtt tcataacgtc cgtgcatgga ttgggtgatt gcgtaaaatg
     9241 cggaaaacag cgcggcgatg gtaaaggagt tgggcagcag gtagatactg ttttgacgca
     9301 gggagcgttg cggggtgttg gtcggggttt ccatagctga agtgtctcac ggacgtggag
     9361 aatcgatagg ggattataac ccaaaccatt atcgaacaat acgcccttta ggatgaagcc
     9421 ctcggaggcg gtttgttttt ctgatggcgg atgctttgcg gggcggtttg actctgcctg
     9481 ccactgggtg tgttgtttcg gatttttgcc ggatggatat tgttgccggg catttctggg
     9541 cttgccggaa ggtatcgggg ggagggcatc ggaatatgcg gcgcaccgtt caaaccgggg
     9601 cggcgtttcc ctattttcag ggggttgcag gtttcaacaa attgaaagat attttttgca
     9661 tttccgaccg tatgctgatt ttgaagcggg ataaattata ggacaaggtt tttcgcccgc
     9721 cgcaaaggtt ggccgcaatg ccgtctgaaa acaacggctt gccgctaagg cggcggtatg
     9781 cggatttgcg ctgccgaaat cggtttgcca tacccggcgg tgcaatctgc ggggagggat
     9841 aagccgataa ggcgggactt atcctgtttt ttgtttataa tgcaacagaa tttggacgaa
     9901 ccgtcgggaa tttatcatga tgaaaaagat actggccgta tcggcactat gcctgatgac
     9961 tgcggcggca cgggctgccg atacttacgg ctatctcgcc gtttggcaga atccgcagaa
    10021 tgcggacgat gttttgcagg ttaaaactac aaaagaagat tcgacgaaaa gcgaagcgtt
    10081 tgccgagttg gaagcctttt gcaaaggtca ggacacgctt gcgggcattg ccgaagacga
    10141 gccgaccgga tgccggtcgg tcgtgtcgct gaacaatacc tgtgtcgcgc tggcataccc
    10201 gaaagccttg ggcgcgatgc gcgttgaaaa cgccgttgtg attacttctc cgcgttttac
    10261 gagcgttcat caggtcgcac tcaaccagtg catcaaaaat acggcgcaca gggacaatgc
    10321 ggcttggaaa cagtgtattg cacgtcttct tcttattacg gcggaactgt gcgctctttg
    10381 attcaaaatc tcaaataaaa cggaaaatgc cgtctgaaag atgttcagac ggcatttcca
    10441 tatcgacggt caggattctt tcggatcggg cagcaggctg ttcaacacaa tggcaagtac
    10501 ggcgcacaag cccacgccgg caaagctgaa gctgcccaat ttgagcgtca tgccgccgat
    10561 gcccgtggtc agtaccgagc tgacgatgac caggtttttc ggcagcatca aatcgacttt
    10621 ggcatcaatc agcgttttca cgcccaaaga agcaatcgtg ccgaacagca gcagcataat
    10681 gccacccatc acgggcatcg gaatggaagc caaaaacgca ttgaatttgc cgaaaaacgc
    10741 catgcagacg gcaaaaaccg ccgcccaagt catgatgaca gggttactgt ttttggtaat
    10801 catcaccgca cccgttactt cgccgtaggt cgtaaccggc gggccgccga tcagaccggc
    10861 aacgcacacg cccaaaccgt cgcccgcaag ggttttgtcc aagcccgggt ctttcgtata
    10921 gtctttcccc gtcacattgc cgattgccat gatgccgccg atgtgttcga tggcgggggc
    10981 gacggcaacg ggcagcataa acagtgcagc ctgccagttg atctgaggcg tttcaaaatg
    11041 gggaacggcg aaccagggcg cgtgtgcaat gcttgccgtg tccaccagtc ccatcagcag
    11101 tgccaaaaca taacccgaag cgacaccgat caagatggga atcagcttca tcatcctgct
    11161 gccgaaaacc gatacgatgg cggtaacggc aaaggtaaag ccggaaagaa tcagcgaatc
    11221 ggtatagtcg atgacctgtt tgccgtccgc ctgacccatt gccatgctgc ttgccgccac
    11281 ggcaacagac agaccgatga ccatgatgac ggggccgatg acgaccggag gcagcagttt
    11341 gtgtaccgct gccagtccgc gccaacggat cagcgcggca aacacaaaat acataaagcc
    11401 ggcggcaaac agtccgaaca tggtggaagg cagcccccat tcgccgacgg agtagataat
    11461 cggtgcgata aaggcaaacg aagaaccaag aaaaatcggc actttgcgtt tggttgtgat
    11521 ttggaacagc agcgttccca agcctgcgcc caaaagcgca agagccggat tcagaccggt
    11581 cagcagggga accagcacca ttgcgccgaa tgccacaaat aaaatctgcg cgccggaaac
    11641 ggcaagtttc agttggttca taccatcttc tttcaatcgg ttcaaacggc acggattata
    11701 ctggtttgcc gagagtctgc gtaaaaatac atatggcggg caacagatat gccgtctgaa
    11761 aggcaatgtc tgtctgttgc aggatgaaag caggagaaat ggagtataat ccgacacttt
    11821 ccatattcaa tccgcaagcc gtccggcttc cttatttcag acggcatttt ccggtaatac
    11881 ggcatgacag aaaaatccca taaaaaaaca gcaaaaggca gggcgggaag cccgtcccca
    11941 acgtccgcac gcaacaagaa agccgacaac ggcgcacggg gcaataaagt ttccgagcgg
    12001 ctcaaggcgg tcaaagagtt gcagaaaacc gaaaccaaaa aggcgcgtcc cgaacatgtc
    12061 gtcaacctta tcggcgacgc actgtggctg atgggtttgg cggcaacctt gtatttggcg
    12121 atttccctga tcagtttcga tatgggcgat ccgtcttggt cgcacagttc gccggttgtg
    12181 gaagatgtcg ccaattgggg cggactgttc ggcgcgtatg ttgccgatgt cggctattat
    12241 cttttcggct ggtcgttctg gtggtggata gcggctgcct gcgtcatgct gtataaaaat
    12301 tttcgtctgc acgcaaaaca gacggaaaat gaggcataca accacaaaat cgctgccgcc
    12361 gcgctgtttg tcctgacggt cttcagcccc gtcttggagt attttgtgct gggcggaaaa
    12421 tatgccgact ccctgcctgt cggagcaggc ggtatggtcg gcatacgcgt cggcgcagtg
    12481 tttgcgtggc tgctggggaa atcgggcagc ctgctgatta tcttggttgt tctgctgttg
    12541 tcgttgtccc tgctggtgca gatttcatgg ctggaatttt tgaacggtgc gggcagggcg
    12601 gttcaaaacc gcctgagtgc cttatccggc aaggtcatgg ctttaggaaa acgccggccg
    12661 aatagcaaaa cagacggtgt cgatacccaa aatacacggc gcatggtaaa agaagccaag
    12721 aatattacgg ccaaacccgt tgccttgccc gaaggcagca gcagcaaccg caaatccgtc
    12781 gcggtttccg tcgcgccgtc gcccaaaatt caggtttctc tgtttgaaga tgacgaacct
    12841 cggcaggcgg gcgaatacca caagcctaca ttgaacctat tgcggattcc tgacagcgaa
    12901 cccgtcagca tcaatcccgc cgaattggag cgcactgccg aactgatcga atccaaactg
    12961 gcagaattcg gcatcggcgt acaagtcgta tccgccacat ccggccccgt catcacgcgc
    13021 tacgaaatcg aacccgcgca aggtgttaaa ggcagccaaa ttgttgcctt gtcgaaagat
    13081 ttggcacgct ctatgtcgct gcaatccgtg cgtatcgtcg aaaccatcgc aggtaaaaac
    13141 acgatgggca tcgagttgcc caacgataaa cgccaagacg tgatgttgag cgaaatcttg
    13201 tcctcgcccg tgtttgccgg agccaaatcc aagctgaccg tcgcgctggg caaagacatt
    13261 gccggtaccc ccgttgtcgg cgacttggcg aaaatgccgc accttttggt cgccggtatg
    13321 actggttcgg gcaagtccgt cggcgtgaac ggcatgatta tgtctatgct tttcaaagct
    13381 acgcccgacg aagtccgctt cattatgata gacccgaaaa tgctcgagtt gagcatttac
    13441 gacggcattc cgcacctgct ctgtcccgtc gtgaccgata tgcgcgaagc agggcaggcg
    13501 ttgaactggt gcgtcgccga aatggaaaaa cgctaccgcc tgctttccca cgccggtgta
    13561 cgcaatctgg aaggcttcaa ccaaaaagtc gaagccgcaa aagcggcagg caagccgctg
    13621 ctcaatccgt tcagtctgaa ccccgacaac cccgagcctt tggaaaaact gccgatgatt
    13681 gtggtcgtta tcgacgaact tgccgacctg atgatgaccg aacgcaaagc cgtcgagcag
    13741 caaatcgccc gtctcgccca aaaagcgcgc gccgccggta tccatatgat tgtcgccacc
    13801 caacgtccca gtgtcgatgt cgttactggc ctgattaaag ccaacatccc gacgcgtatg
    13861 gcgtttaccg tgcaaagcaa aatcgacagc cgtaccatcc tcgaccaaat gggcgcggac
    13921 gaactgctca aatatggcga ttcgctgttc ctccagcccg gcagtgccga accgacccgc
    13981 ctgcaaggcg cgtttgtttc agacgacgaa gtacatcaag tcgtcaacta cgtcaaatcg
    14041 caagccccag ccgactatat tgaaggtctg ctcagcggcg aggccgcgct ggaaactgcc
    14101 aatatcgtta atccgaatgc agacagcgac gaattgttcg atcaggcagt cgcctatgtt
    14161 ttggaaagca aaaaaacctc catttcgtct ttgcagcggc agttgcgtat cggctataac
    14221 cgcgcggcaa acctgatgga ggcactggaa aatgcgggtg tcgtttctcc caccgacctc
    14281 aacggcagcc gtaaaatttt ggcgcacaag gaccatttgt agcccgtatt gcaaaatgcc
    14341 gtctgaacgg cggaattggc gtttcagacg gcatattatg tttcaggcgg aacattgtga
    14401 tatacttgcc agctaaaatc tcccctttgc ggcaatgcgg ttcaaatatc cgtaccgttg
    14461 cgctgtttgc ttccccatgc agggaagaag gtttaccatt ttatcaacac aacaaattta
    14521 agggcttatg atgagcgtaa ctgttgaaac tttagaaaat ctggaacgca aagtagtgtt
    14581 gtccctgcct tggtccgaaa tcaacgcaga aaccgataaa aaactgaaac aaacccagcg
    14641 ccgtgcaaaa atcgacggtt tccgcccggg taaagcacct ttaaaaatga ttgcccaaat
    14701 gtacggtgcg agcgcgcaaa acgacgtgat caacgagctg gtgcaacgcc gcttccacga
    14761 tgttgccgtt gcccaagagt tgaaagtggc aggcttcccc cgttttgaag gcgttgaaga
    14821 acaagacgat aaagaatctt tcaaagttgc cgccattttt gaagtgttcc ccgaagtcgt
    14881 tatcggcgat ttgtctgcac aagaagttga aaaagtaacc gcttccgtcg gtgatgccga
    14941 agtggaccaa accgtagaaa tcctgcgcaa acaacgcacc cgcttcaacc atgtcgaacg
    15001 cgaagcccga aacggcgacc gcgtcatcat tgactttgaa ggcaaaatcg acggcgaacc
    15061 ttttgccggc ggcgcatcca aaaactacgc cttcgtattg ggcgcaagtc aaatgctgcc
    15121 tgaatttgaa gccggcgtag tcggcatgaa ggctggcgaa agtaaagacg ttaccgtcaa
    15181 cttccctgaa gaataccacg gcaaagacgt tgccggtaaa actgccgtgt tcaccattac
    15241 gctgaacaac gtttccgaag cgactctgcc tgaagtcgat gcagattttg caaaagcctt
    15301 gggtattgcg gatggcgatg ttgccaaaat gcgtgaagaa gtgaagaaaa acgtaagccg
    15361 cgaagtggaa cgccgcgtga acgaacaaac caaagaatcc gtaatgaacg cgctgctcaa
    15421 agccgtagag ttgaaagttc cggttgcttt ggtcaatgaa gaagccgccc gtttggcaaa
    15481 cgagatgaaa caaaacttcg tcaaccaagg catggccgat gccgcgaact tggatttgcc
    15541 tttggatatg ttcaaagaac aagccgaacg ccgcgtgtct ttgggtctga ttttggccaa
    15601 actggttgat gaaaacaaac tggaaccgac tgaggagcaa atcaaagccg ttgtcgccaa
    15661 cttcgcagaa agctacgaag atcctcaaga agtaatcgac tggtactacg cagagccttc
    15721 ccgcctgcaa gtcccgactt ctttggcgat agaaagcaac gtcgttgatt tcgttttggg
    15781 taaagccaaa gtaaacgaaa aagctttgtc ttttgacgaa gtgatgggcg cgcaagcctg
    15841 attatcctga aaatgccgtc ttagggcagt ttttgaaagc accgaagccg cttttaaagc
    15901 ccgctttggt gcttttacat catgaaagga gacgaaatgt cttttgataa ctatcttgtc
    15961 cctaccgtta tcgagcagag cggtcgcggt gagcgtgcat tcgatatcta ttcccggctt
    16021 ttgaaagagc gcatcgtatt cttggtcggc ccggtaaccg acgagtccgc caatctggtg
    16081 gttgcccaac tgttgttttt ggaaagtgag aatccggata aggatatttt cttctatatt
    16141 aactcgccgg gcggttcggt aacggccggt atgtcgattt acgacaccat gaatttcatc
    16201 aagcccgatg tatcgacttt gtgcttgggg caggcagcaa gtatgggcgc gttcttattg
    16261 tcagcaggcg aaaaaggcaa acgtttcgcc ctgcccaaca gccggattat gattcaccag
    16321 cctttaatca gcggcggctt gggcggtcag gcatccgata ttgaaattca cgcacgcgaa
    16381 ctgttgaaaa tcaaagaaaa actcaaccgc ctgatggcga aacattgcgg ccgcgatttg
    16441 gcagatttgg agcgcgacac cgaccgtgat aatttcatgt ccgccgaaga ggctaaagaa
    16501 tatggtctga ttgatcaaat cttggagaac cgtgcttctt tacagtttta ataagaaatc
    16561 tgagagaaac aaatgccgtc tgaaaacagt tcaggacggc atttgtctta tagggactgt
    16621 atagggatga ttttgttctg gttgcgtttg gagccgtttt caccatagtt ggttttgaca
    16681 tattcctcta caatagctag gaattcagtt gcaatattat cacctttcag tgttattttg
    16741 cgctccccgt ccacataaac cggcgcgacg ggtgtttctc ccgtaccggg caggctgatg
    16801 ccgatgtcgg ccaatttgct ttctccgggc ccattgacaa cgcagcccat tacggcaacg
    16861 ttcagggatt caaccccagg ataaagggta cgccatatag acattttttg gcgcaggtaa
    16921 ttttgaacat cttgtgccag ctcttgaaat acggtactgg tggtacgccc gcagccgggg
    16981 caggcggtaa ccatcggcgt aaacgaacgc aatcccatag tctgtaaaat ctcttgcccg
    17041 acgacgacct cctgagtacg cgggctgcca ggttccggag tcagtgaaat gcggatggtg
    17101 tcgccgattc cttcttgaag caagacggat aatgccgccg ttgatgcgac aatgcctttg
    17161 ctgcccatac cggcttcggt caaacccaaa tgcagcggat aggcgcaacg gctgcccagt
    17221 tcgcggtaaa cctgaatcaa atcctgaacc gcgctgactt tgcacgacag gatgattttg
    17281 tcttcgggca gtcccaatag aacggctttt tcggcagatt ccaaagcgga gacaatcagt
    17341 gcttccttcg tcacttcttc gggcggtttc ggcgcggaag aagcgaggtt ggcatccatc
    17401 atacgtttgg cgaggctttg atccaaagaa ccccagttta cgccgatgcg gacggcttta
    17461 tcgttttcag cagcagtccg aatcataaag gcaaattttt catcgccttt tacgcctttg
    17521 ccgacattgc cgggattgat gcggtatttg gacaatgctt tgccgcattc gggaaattcc
    17581 gccaacaggc gttcgccgtt gaagtggaaa tcgccgataa gtggtgtggc atagcccata
    17641 tcgtccaagc ggcggcggat ttcggcaact ttggacgcgg cttcggggct gttgacggta
    17701 atacgcacca tttcggatcc ggcatcgctc aattccttaa tctgcaatgc ggtggctttt
    17761 gcatcggcag tgtcggtgtt ggtcatagat tggataacga cgggtgcttc tgaaccgacg
    17821 gtaatatgat cgatgcggac ttgatgcgtc ttgcggcgtt ggagtgtgtt catatggttt
    17881 gaatctgttt attgaccgat gaggacggtt tgcaattctt ccgagtaggg gaaattcgcc
    17941 tgcaattgtg cttcatattc gtatgccgcc tgtgcgttgc cgagggcttt ggcaattttc
    18001 cagcctagca gcaaatcatc ggcctgaagg acttctaccc tgctttggta ttttttaaag
    18061 tagtaatcgg catcgcccaa ctgcccggcc agcattttgg tgcgcgccag ttctttaaat
    18121 gcgggtggga actgcggctg ggcggcgagg gaacgtttca aataggcttc cgccaatccg
    18181 aattgcccct gttttgcgct gcatatgcct ttattcaggt tggcaatata aggggtcggg
    18241 taggtggggt cggccagggc tttgtcgaaa tatgccatag attcggcagg gcggttgagc
    18301 ctgccgcaca ggaaccagcc gtagttgttg ttgatttcgg cactgtcggg tttgatggag
    18361 agggcttgcc ggaaactttc ctgcgccttg tcgttaactt tcaggtattg atagatttcg
    18421 gcacggacca gccaggcaag ctcgttttta gggtccgatt tcagggcgtc ttcaatactt
    18481 gccgtcgcct gacggtagtc ctgaccgcgc atatattcca ttgccaactg ggttttgata
    18541 ttggaaacct gattggcttt ttctgcccgc gaggggcggt aggaagtgct gcacgcgccc
    18601 aaggcaagga caagtaataa agagattcgt ttggatggct taaaaggcat aattacccct
    18661 gttgtccgat taaaatctgc tgccattttt gttggcggcg cgttttatcc tgaacctgcc
    18721 ccgccaactg tccgcaggcg gcatcgatgt cgtcgccgcg cgtttttcgt acggtaacga
    18781 caaatcctgc ctgctgcaaa atatcgcgga acacacggat gttctcattg ctggagcgtt
    18841 cgtatccaga gtttggaaag ggattgaacg gaatcagatt gaacttgcag ggaacatctt
    18901 tgaccagttc gatcagttcg cgcgcatgtt gcgccttatc gtttattccg tccaacatga
    18961 cgtattcgaa agtgatgaaa tccctgggtg ctttgactag atagcgttgg catgcagcca
    19021 tcaattcttt caagggatat tttttgttca acggtacgat ttggttgcgg acttcgtcat
    19081 tggaagcgtg gagggaaacc gccaaagcca ccggcatgac atcgcgcaac ctgtccattt
    19141 ggggaaccat acccgaagtg gaaacggtta cgcggcggcg gctcaaaccg tagccgtggt
    19201 cgtccagcat gatgcttaag gcggtaacga cattgtcgaa gttcgccatc ggctcgccca
    19261 tacccatcat cactacattg gaaattacgc gttcgttttt cggtgtaaca cccatcgctt
    19321 tgtttgccca ccacaattgc ccgatgattt cggcagcagt caaattgcgg ttgaagccct
    19381 gccggccggt cgaacaaaat gtacattcca aagcgcagcc gacttgtgag gaaatgcaga
    19441 gcgtgccgcg atccgattcg gggatgaaga cggtttccac cccgttgccc gtaccgacat
    19501 ccaaaagcca ttttcgagtg ccgtctgaag atttttgaga catcatcagc ttgggaattt
    19561 cgatgcctgc ctgttcgttc agtttatggc gcaacgattt tgccaaatcg gtcatttcgt
    19621 taaaattttg cgcgccggat tggtgcatcc aacgcataac ctgtttggca cggaagggtt
    19681 tttcgcccat atcggcaaaa tgtcgggtca gcccttgaag gtcgtagttg agcagattgg
    19741 ttttcatgtg tttgtgtttt tcttaaatta aggcttcaaa taaaaaattg cagggcaggc
    19801 aagtttgatt tgaagccttt tgcgacagag ttttcagacg gcatggatat atttatgccg
    19861 tctgaagagg agttgggcgg tgtattgtat caacgggggc agatttcggt ttggctgaaa
    19921 aagtaggcaa tttccaaagc ggcattttcc acgctgtcgg aaccgtgtac ggcattaatg
    19981 ctgaccgaag tggcaaagtc cgcgcgtatc gtgccttcgg cggcttcggc gggattggtt
    20041 gcccccatca gttcgcggtt tttcagaacg gcgttttcgc cttccagtac ttgaatcata
    20101 accggaccgc cggtcataaa ttcaaccaat ccggcgtaga aggggcggtc tttatgaacc
    20161 gcataaaatt cttgcgcctc tttgagagta agctgcttca ttttggcggc aacgattttc
    20221 agaccgttct cctcaaagcg gctgtatatt ttgccgataa catttttgcc gacggcatcg
    20281 ggtttgatga tggagatggt gcgttcaatc gccatgctat atccttattt ttacttaaga
    20341 agaatcaaat cggtattcta tcaaaaaaat aacttatccg cctgaagcct tgggagatag
    20401 ggtcaggtgc ggctgttcca aataaacttc ggactgcatt tcgaccatcc ggctggcggt
    20461 gcgggtaaat tcttcggcaa aatcgccttc cgtatagata tggttgacat ctaccgcgcc
    20521 ggtggcacac agtttgaccc ggaaatcgta gagtacgtca atcagccaag tcagccgccg
    20581 cgcctccgcc ttttcttgcg gtgagagttg ttccaaacct gaaataaaaa ccatttcata
    20641 atgttcggcc aaatacagat agtcggactg tgagcggggg ccgaagcaca gtgcgcggaa
    20701 atcaaaccat atggcacggc cggactcggc tttgtgggga atctcccgac catggatggt
    20761 gctgatgccg gggttcaaat cggtaatgcc tgtcatttct ttgaacagtt ttgccagttt
    20821 tgcctcattt tcttcattgg caggcgtaaa gaaaatctcg gcggggcgga gggtacgcag
    20881 tcggtagtct tcaccgccgt caacgtttaa gacggtcagg ctggactcga tgatcgcgat
    20941 tgtgggaaga aaactgctcc ggttttgacc ttgcgggtag agttcggaag gcgcgtagtt
    21001 tgaagtcgcc accaaaacaa cgccctcgtt aagcaggttt tccagcagac ggcctaaaat
    21061 cattgcatcc gcaatatcgc tgacatgaaa ttcgtcaaaa cacaatacgc gggtttcttt
    21121 ggcaatctcg gcggcaacgg atttcaacgg gttgctttcg cttttcaggg ttttcagcct
    21181 ctggtggatt tctgccataa aggcatgaaa gtggacgcgg cgtttgcggc ggtaagggag
    21241 gcagccgaaa aaagcgtcca tcagaaagct tttgccgcgt ccgaccccgc catagaaata
    21301 aagccctttg gggacttgcg gggaacgcaa actcctgcct aaaaaacggt ttcttttgcg
    21361 tttgaacatc atcaattcgg tccaaagccg atcgaggtgt tcgatggcgg ctgcctgcgc
    21421 gtcgtcgcgg atgaagttgg gcagttgtga ggcagcctga taccaggtca gcgggctgtg
    21481 gttttcaaac ggcggggctt taaaaagttg gtctctatta ctcatattta accttgttat
    21541 acttcttgcg gcggagaaag aaaatgctta ccgtcggtat tataaatgat ttccttcaaa
    21601 cttggcattt tccgtggaaa agaataatga cgcgcacaag ggggtataag caaaggcggc
    21661 gtttcaatat ggtgcagata tgagctcaaa tgccttttat agtagattaa atttaaacca
    21721 gtacagcgtt gcctcgcctt gccgtactat ctgtactgtc tgcggcttcg tcgccttgtc
    21781 ctgatttttg ttaatccact ataatccgta gagtcggctc cttccggctc agacggcata
    21841 cgtttatgcc ggcacttctt accgccctcg tgccggctat cccaaaactg ctttgaacac
    21901 tgaacgctct ttggtttact tcaaaaacgc ggcgtgataa gcaatatgct cgccaataaa
    21961 actggcgatg aagtaatagc tgtgatcgta gcctttatgg aaacgcacat cgaccggctg
    22021 gtttgccgca cggcaggttt cgataaaatc ttcggtacgc aattgtgtcg gcaaaaactc
    22081 atcttccaag ccttgatcga tgcgcatacc ttgcacttta tagccttgtt gaatgagtga
    22141 gttcgcatca tattgctgcc atttttcacg gtctttccct aaataagcag taaaggcttt
    22201 ttctccccac ggcacgaggc ttggcgataa aataggcgaa aaggcagaaa cactttgata
    22261 acgttcctga ttccgcagcg ccaataccaa tgcgccgtgt ccgcccattg aatgccccat
    22321 aatggaacgt ttgccgttgg taggaaagtg tttctcaatc agacggggca gctcgttcaa
    22381 aatgtaatca tacatttgat aattcgccgc ccaaggctgt tcggtcgcat tcaaataaaa
    22441 gcctgcaccc tgtcctaaat cgtaagcatc atcgttcggc acttgctctc cgcgagggct
    22501 ggtatcggag gccaccacaa ttacttgatg ttctgccgca taacgctgaa agcctgattt
    22561 ggtaatgaaa ttttgttccg tacacgtcaa gccggaaagc caataaatca caccaagcgg
    22621 tcgattttct ggattatttg gcaaatagac ggcaaatttc atttcgcatt gcagcgtttg
    22681 ggcatgatgc gcccaaactt gttgcgaacc gccaaaaatt tgatgttgtt caatcagttt
    22741 catcgcatac cttagtagtg aataacggcg cggatcgatt taccttcgtg cattaagtca
    22801 aaggctttat tgatttgatc gagtgtcatt gtgtgggtta caaacggttc taactcaatg
    22861 tcgcctttca ttgaatcttc caccattttc ggcagttcag agcgaccttt cacaccgcca
    22921 aatgctgaac ctttccaaac acgacctgtt accaactgga acggacgcgt tgaaatttct
    22981 tgtcctgcac ctgctacgcc gatgataatg gattgacccc aaccacgatg tgcactttct
    23041 aatgcttgac gcattacgtt tacattgccg atacattcaa aggtatggtc aatgccccat
    23101 ttattaatgt ctaacaacac atctttaatt ggtttatcgt aatcgttcgg gttcaaacaa
    23161 tccgttgcac cgaactgttt tgccaactca aattttgatg gattggtatc aatggcgata
    23221 atgcggccgg ctttggcttg acgcgcacct tgcaccaccg ccaaaccaat cgcgcctaag
    23281 ccaaacacgg caacagagtc gccttcttgc acttttgccg tattatgtac cgcaccaata
    23341 cctgtggtaa cgccgcagcc gagcaaacat acttgttcat ggttggcttc agggttgatt
    23401 ttcgccagtg aaacttcggc aacaacggag tattcactga aagtcgaaca gcccatatag
    23461 tgataaatcg gctgaccttg ataagaaaaa cgcgtcgtgc cgtccggcat taagccttta
    23521 ccttgtgtat cacgcactga gacgcacaag ttggttttac ctgaacaaca aaactcacat
    23581 tcgccacatt cggcggtgta aagcggaatc acgtgatcac ccggttttac gcttgacaca
    23641 ccttcgccca cagcaacgac cacacccgca ccttcgtgtc caagcaccac agggaatacg
    23701 ccttcaggat cgcttcctga taatgtaaac gcatcagtat ggcacacgcc agtgtgggta
    23761 ttgcggatta acacctcgcc tttacgcggc atttctacgt cgatttccac aatttgtaag
    23821 ggttggttag gggcgaatgc caccgccgca cgagatttga tggttgaatc ggtttgtttc
    23881 atttccattg tctttcctct taattcattg acaaagttgc cttacctgag caacatagca
    23941 acagtttaca ctttagagtt aactctaaag caagtgtttt ttactgtttt tgtttagaag
    24001 gagggaaaat ggcttatacc actgccaaag ccgccgaaaa aataggcatc tccgcccaca
    24061 ccctacgttt ttacgacaaa gaaggcttgt tgcctaatat cggacgtgat gaatacggta
    24121 accgctgttt taccgataac gatttgcaat ggttgggctt attgcaatgc ttgaaaaata
    24181 cgggaatgag cttaaaagac atcaaacgct ttgcggaatg taccgtcatt ggcgacgata
    24241 ccattgaaga acgcctttcc ttgtttgaaa atcaaataga aaatgtgaag tgtcaaattg
    24301 ccgaattaaa acgctattta gatttgcttg aatacaaatt ggcgttttac caaaaagcga
    24361 aagcattagg ctcggtaaaa gctgtaaatt tgccgcaaat tcctgaaacg gcttagtttt
    24421 agtgcaataa gcaggatttt tgtcctgttc gtaatagaaa tcaaaaattt gttgtttaaa
    24481 aagcggattg taagcaatga tatagtggat taacaaaaat caggacaagg cgacgaagcc
    24541 gcagacagta cagatagtac ggaaccgatt cacttggtgc ttcagcacct tagagaattg
    24601 ttctctttga gctaaggcga ggcaacgccg tactggtttt tgttaatcca ctataaaaaa
    24661 atccacgctc taatccgttg cttgcttggc tcaaggtatt gaagcaacgg atgaagttaa
    24721 accacagaaa aaacgccgcg taacagcggc gttttgatgc taaggtttaa ttggcatttt
    24781 cttttaaagc caagtcgacc cgctcgcgca attctttacc gggcttgaag tggggtacat
    24841 gtttttcagg tacttccaca cgctcgccgg ttttgggatt gcgaccgatg cgggcaggac
    24901 gatggttcaa atcgaagctg ccgaaaccgc ggatttcgat gcgttgacct cgggcaagcg
    24961 atctagtcat ggtgtcaacc aagactttta cgctgtactc tacgtctttt gccagaagat
    25021 gcgtgccgtt tttggcggca aacacttctg ccaaacgaac cattaactca gactttgtca
    25081 tgtctgcaac cttattcttg ttcgccggag agtttggctt tcagcaggtc gcccaagctg
    25141 gtggtgccgg cattcgcatt ggcggcggca ttgacggagt tcagtgcttc gcggctttct
    25201 ttggcatctt tggctttaac ggaaagtttg atgctgcggt ttttgcggtc aacggtaacg
    25261 atgacggctt caacttcgtc gccttctttc agtttggtgg tcaaatcttc aacgcggtcg
    25321 gctgcaaatt cggaagcagg caggtagcct tctacttcgt cagacagggc gataacagca
    25381 cctttggcgt caacagattt cacggaacct ttaaccaaag aacctttgtc gttcacgctg
    25441 atgaagttgc cgaacggatc gccttccagt tgtttgatac ccaaggagat gcgttctttt
    25501 tccatgtcga ttgccaatac gacggcttcg acttcttcgc cttttttgta tttgcgtacg
    25561 gcttcttcgc cggattcggt ccaggacagg tcggacaggt gaaccaaacc gtcgatgccg
    25621 ccgggcaggc cgacgaatac gccgaaatcg gtaatggatt taaccgcgcc ggagattttg
    25681 tcgcctttgt tgtggttggc ggcaaattct tcccaaggat tggcttggca ttgtttcata
    25741 cccaaagaga tacggcggcg accttcgtcg atttccaaaa tcatgacttc gacttcgtcg
    25801 cccagttgta cgactttgct cgggtgtacg tttttgttgg tccagtccat ttcggagacg
    25861 tgtaccaaac cttcgatgcc ttgttcgatt tcgacgaatg cgccgtagtc ggtcaggttg
    25921 gatactttgc cgaacaggcg ggtgccttga ggataacggc gggtcagacc gctccaagga
    25981 tcttcgccca gttgtttcat acccagagaa acgcgttgtt tgtcttggtc gaatttcagg
    26041 actttagctt ctacttcttg accgacttcc agaacttcgc tcgggtgttt cacacggcgc
    26101 catgccaagt cggtgatgtg cagcagaccg tcgatgccgc ccaagtcaac gaatgcaccg
    26161 taatcggtaa tgtttttaac gatgcctttg atgacgaagc cttcttgcag gttttccagc
    26221 agggctttgc gttcttcacc caaggtagct tccagaacgg cgcggcggga aaccacgacg
    26281 ttgttgcgtt ttttgtccag tttgatgact ttgaattcga tttctttgcc ttcaaagtgg
    26341 gaagtgtctt taacgggacg tacgtcgacc aaagaacccg gcaggaatgc gcggatgctg
    26401 ttgatcataa cagtcaggcc gcctttgact ttgccattga taacgccgga caggatgtcg
    26461 ccgttttcca tggcttcttc cagggcaatc caatcggctg cgcgtttggc tttttcgcgg
    26521 gacagtttgg tttcgccgaa gccgttttcg acggattcga tggtaacggt aacgaagtcg
    26581 ccgactttga cttcaatttc gccttgagcg tttttgaatt cagctacatc gatcagggat
    26641 tctgatttca gacctgcgtt tacggtaacg aagttttggt cgattgccac tacttcagcg
    26701 gtaatcacct cacccgggtt catttcttgc agggtaaagc tttcttccaa cagctgagca
    26761 aaattttcca tagacatata taactctttt cggtacaccg ccaaggggtg cggggtgggt
    26821 tggtgggtgt ctgccgtcct tggcagggca gacgggtaca taaggtttca gacggcatat
    26881 ggggaaattc atgctgtctg aaacgcaatg cgggcgatta tacctgaaaa tttaaacttt
    26941 acgataccaa tcaagcactt tttttacagt ttcttctata gtcaggcggc tcgtatccaa
    27001 aagcagggca tcgggttgtt gtttcagggg ggcaaccttg cggtttcggt ctgcctcgtc
    27061 tctggcttcg atgtcggaca ggatgcgctc gaatgccaaa ccttcgcagg ggatgccgat
    27121 ttgtttggcg cggcgttcgg cacggatttt ggattctgcc gtcaggaaga ttttaagttc
    27181 ggcttggggg aagacgaccg atccggtgtc ccgtccgtcg gcgaccagtc ctttttcggt
    27241 cagaaaatcg cgttggcgtt gcagcaggga ggcgcggact ttaggcaact gtgcgactgc
    27301 ggatgcgccc atgccgatgg cttctgtccg gatgccgtct gaaacgtctt cgccgccgag
    27361 caggatgcgg ctgtctgaaa atacggcggg cagttttttt gccagttcgg aaacgttttc
    27421 ttcatcgtgc catcccacgc cttgtttttg tgcatatagg gcggtcaggc ggtagagtgc
    27481 gccggtatcg agataatcgt atcccaatgc ggcggcaacg cgggcggcaa ccgtgccttt
    27541 gcccgatgcg cccgggccgt cgatggcgat gactttttgt ctgttcataa gggggattcc
    27601 tgatggtttg gggtatgggt tttgccgtct gaaggatgtg tttcccgttg gggcggattc
    27661 tacctgtttt aaaggacgat tgtctaagca gacggaacgc cgcctgcccg gaaatatccg
    27721 acagaagccg gcaagccgat tcggattccg gcgttgcggg tattgtggcg ggcatcaatg
    27781 taatgccgtc tgaagtcagt atggctttca gacggcatta atcggtgtga atcagaaaag
    27841 gttgctgacg aaaatcagca gaatcaccaa cggcacaaga tatttcacat aagcaaacca
    27901 aatattgacc gtcgtatggt tgcctttata aagcaattct tccttcgctt catctttcat
    27961 cacgaagccg acaaacaagg ccgaaccaag cgcggtcagc ataaacaaga tgttgccgct
    28021 gatgtagtcg aaggcatcga aaatattttt gccgaacacg gaaacgtctt tccacggacc
    28081 atagctcaga atagacggga tgttgccgaa aatgaagatg gcagccaata caatcgtaat
    28141 cgcggcggtg cggcggattt tggttttttc ctgaatggtc gtaatcaata cttcataaat
    28201 cgtcagcgaa gtcgtcaacg cggcaatcag gagcagcgag aagaaaatca cggcgaacac
    28261 agatcccgcc cacatatgtg agaacacaat cggcaagctt tggaacacca aagtcgggcc
    28321 ggaatcgggg gcaacgccga agctgaagag cgacgggaaa atcataaagc ccgcaagtat
    28381 ggcgatgatg gtattggtaa ttgccgtgat aactgccgtc tgaaccagat tttcgttttt
    28441 atccaaatag ctggacaagg taatcatcac gccgaaaccc aggctcaggg caaaaaatac
    28501 ctgccccaaa acgaagacga acagttcggc ggtaatcttg ctgaaatcag gtttcagata
    28561 gaaagcaacc ccttccattg cgcccggaag ggtaacgttg cggacgacca tcgcaattag
    28621 gaacaaaaac agcagcggca tcagctattt tgccgctttt tcaatgccgc cgataacgcc
    28681 tttgaccaaa atccattggt tcacggcgac aaaaagcagc gtataaaacg caatttccca
    28741 agggctgttt tcgatgtgtt cggtaaagaa gctttttgta accataccgt cgacggggct
    28801 ggaaatgtcc agattgccgc cgataatgtt gacgatatag ctgattaccc agccgccgag
    28861 caccatataa taagccataa tgccgaacgc gccgagcagt cccgcccagc cgaccagctt
    28921 ccaaatttta gcgacgggtt tgccgttcat cgagccgccg aacgcatcca gcgcgttcac
    28981 gcctttgcgc cgtccgatga cgttttccac caaaatcatc ggtataccga taacgagcat
    29041 ggcgatacag aataaaaaca catacgcgcc gccgccgttt tcaccgacca aatacgggaa
    29101 acgccacgtc gcgccgaagc cgacagtcgc gccggcaacg gtcaggatat aggttaatcg
    29161 gctggatcag gtttgacgat tggtatttga aggggaagac atattgaaac cgtgtccgat
    29221 tgagataaag cggaaattct acacgcgttt tttaacagga actgactgat tgcttttcaa
    29281 ctgtctagtg attttccatg taaaaggcat atatttcagt gagtatttct gatgagtata
    29341 acccgatgag gaagaatcgg agtttataaa tagattaatt tgttattctt ctacatcggt
    29401 gtatggaaat gaaattttgt taattatatt aatgatagca tttaaataat gatgaaagag
    29461 agggaatttg aaatatagtg gattaacaaa aatcaggaca aggcgacgaa gccgcagaca
    29521 gtacaaatag tacggcaagg cgaggcaacg ctgtactggt ttaaatttaa tccactataa
    29581 aaaaaccatc tatacaaggg gagaagtata gatggcaaaa cacattacgg ggaaaacgtc
    29641 ttactcataa gcctgcttga acaggcgtta ctcagacaaa tggattatat cgtaaattga
    29701 ttttttgcgt taaattgggt taaaccatat atttaatgag tatgtggatg aatataaatg
    29761 gaattcttgg atgttatttc agaattttgg acattcgata aatttccatt ccccgggttt
    29821 gaggttttct gtttccagat gtgcgaatcg ccggcgatga aggtgttgca cgcggttgcc
    29881 ggcggcggcg atcatgcgtt tgacttggtg gtattttcct tcggtaatgg tcagcagcag
    29941 ggtggtcggg ttttccaaaa cggcatcggc ggcacaaacg gtttcgtttt cgtcgtggag
    30001 cagcacgccg tttttcaagg tttcgcagag cgtttctcct gtggggtgtt tgagcgttac
    30061 ttcgtatagc ttgggaattt ttctgctcgg cgaagtcagg ttgtggttca gtttgccgtc
    30121 gttggtaatc agcaatacgc cggtcgtatc cgcatccagc ctgccgaccg cctgcatatc
    30181 gatgttccgc atattgtcgg ggaacaggct gaatacgctg cggtagtgct tgggtttgtg
    30241 cgaagtttcg taatcttcag gcttgttgag catgatgtag aaatagggtt cgggaacgac
    30301 ggttactgct tccccgtcaa tatccaacgt ttcgacggat gaggaatcga tgtctgcatc
    30361 ggtgtcgtcc atgcaggttc cgttgatgaa aacataaccg ccggcaatca gccattggca
    30421 ctgcttgcgg cttcctatgc cttgatattg caggtatttg atgagtttca tgatggtatg
    30481 ggaaatgtgg gatgaaaaag acgggactga gaaagtcctg tcatgtgccg tatccgaatc
    30541 agcttccaat cagtttgacc ctctgtcccg gattgatggt gttcaggttg ggattcagcc
    30601 ggcggatgtc gtcgatatgg atattgaagc gcgcggcgat acttttgaag gtgtcgcctt
    30661 tgcgcgcggt gtaggatact ttttcaatac gggtttgggc gggggctgcc tgctccaggc
    30721 ggagtacctg tcctttttgg atggtgttgc ctttgatgtt gttggcgaca atcaggtcgg
    30781 ctacgctgac attgtagcgt ttggcaatgt tgaacagggt gtcgccttct acaacgcggt
    30841 ggatgctggc atggagcggg gagatttcgg cttcgccgtc ggcagctttg gctatacgtg
    30901 tttccaaacg tatccggcgt ttgccgtcgg cggcagcggt atgttgcgga gatgcggaaa
    30961 ttttgtgttc ggcaactgtg tcaggcgtgc cgatgacggc ggagatggtt tcttcagcct
    31021 gtcggcgcag gttgtttcgg gcaacaagct gcatgagttc gtctgccgcc tgcatgtcgt
    31081 tttgggggat gatctgcgcg agtgttgcgg tttgggtttc agacggcatg gcggtctgtt
    31141 tttcggtttg aggttgcgct gcggctgtcg caagggcagg ttcggcaata cggacaaggg
    31201 gatcgggttc cgtacggacg gttttctgcg gcaaaggtgc gacggtaatg tccgctgtct
    31261 gtgcggcggc gggtcggatt cgggcaatgc cgacgttcac cgtgcctgcc ggcatattgg
    31321 aacggtaggt gtcgggcgta ttgtcgatgt cgatggaaac gacggattcc gatgccgtct
    31381 gaagggtttt gccgttcttg gcgacaagga tgctgcgtcc tgcgttgaca aggttgccgt
    31441 tcaggttgtt gaggcgtttg atgtcggcaa tgctcatgcc ggttgccgtc gagatgtcgg
    31501 acaggctggt tttggcggca ggcgtataga cttcccatga aaacaggctg tcgggtgcgg
    31561 cgttgaggta gttgctttgg aaggtttgta cggacgcgac aggaagcagc agtttgcgtt
    31621 tgcttttggg gataaacgcg gggacgttga atgcggggtt tagggcgagc agctcgcttt
    31681 gcgtgatgcc ggcaagccgg gcgatggctt cgttgtcgag cggacgatcc ggttcgactg
    31741 cctgaaaata gggtttgttg tctatgtcgc tgatattcat gccgaaagat tggggagtgg
    31801 caataatgtt gcgcacggcg agcagcttgg ggacatagtt gcgcgtttcg ttgggcatac
    31861 gcaggttttc gtaggtcggt tcgagccctt gggcgcgggc gcggttgatg gcgcgtccga
    31921 cgttgccttc accccagttg taggcggcaa aggcaagcgg ccagtcgccg aacagtccat
    31981 agaggtattg cagatagttg agtgcggcat cggtggcggc gtaaacgtcg tgcctgccgt
    32041 cgtaaaccgg tgttttttcc aggccgtaat gcctgccggt agcgggcata aactgccata
    32101 atcctgatgc gccgacgtgt gatttggctt tggtgacgaa cgcgctttcg atgaagggaa
    32161 gcagggcggc ttcggcgggc atattgcgtt ttttgacttc gttggcgata tggtacatat
    32221 agggtctact ccggttgatg accctgttga aatagctgtg gcttgcgatg aatttgcttt
    32281 cgtggcggcg taccagttcg ggattgactt cgcccatccg gaagccttgg cgcagctcgc
    32341 tccacaggct gccggattgg aaatattgtt ttgtcggggg caggtcgagt attgaagagt
    32401 ttaagcgcat aatcgccaaa ccgatttggt gtgatgaggt gttttgggcg tataggaaac
    32461 ccggacaaac ggacagacct gatgcggtca gagcgatggt tttgagtttg gacatgattt
    32521 atattcggcg gaataaacat attttatcgt ccgatggtac tgtttgactg aaaaagcgtc
    32581 aagttttaca ggaactttat gcggattcgg aaatgggcgg ccgatgtgtt ttttgacaga
    32641 aatcctgttt ggaatagaat atcggcaggc aatctgtttg aaacggacgc aatatggatt
    32701 catggtttga agatacggcg atggggcggt atgttgcaaa attggaacag gatttcttcg
    32761 ggcggtatct ggattcatac cgtttttcgg gaatgtgtgc ggttcaggtg ggcggtccgt
    32821 ggctgagcct gtctgaagat gttgtctgtg tgccgcgaga tatgtcgatg tcggcggaaa
    32881 atatggcttt ggcggatgtt tctgcggata tgctgctttt tccgcatacg cttgaaggcg
    32941 gtgttccttc gcaaatcctg tccgaggcgc accggatatt gaaaccgtcc ggacgtttga
    33001 tgctgacggg tttcaatccg tattcgctct ggggattcag ccgttggttt gacggcgaac
    33061 gcctgccgga aaaacgcttc tgtctgccgc tgcccgagtt gaaaagacgg cttgcggatg
    33121 tcggtttcga tattgaattt gggaaattta tggtgtatct gccgccggtt tcgtcgctcg
    33181 ggcaaatacg cttttggcgg tttatggaaa aggcgggcga ccgttggtgg ccgcagtgtg
    33241 ccgcagtgta cggtttggtt ttggtcaaaa gggcggcggg cgtaacgccc ctgcccgcgt
    33301 gggacgggta tttgggcggc aaagcccttg cggcgggtgc ggcaagggtt gcggattagg
    33361 gacagccgtc tttcagacgg catctgtcag aagaaatgtc gggaggggtt atgcctgaat
    33421 tgccggaagt ggaaacgacg ttgcgcggca tcgcgccgca tattgaaggg aaaacggtgg
    33481 aagccgtggt attgcgccaa ttgaagctgc gctggcagat taatcccgat ttgggggaga
    33541 ttttgtccgg ccggcaggtt ttgtcctgcg gcaggcgtgc caaatatctg attgtccgtt
    33601 tccaaacggg gattttgctg attcacttgg ggatgtcggg cagcttgcgg atttttacgc
    33661 cgtcggacgg acgtatcggc aggccggaca gacacgatca cgtcgatatt gtgttttcag
    33721 acggcacggt catgcgttac cgcgatccgc gaaagttcgg cgcgatactt tggtatgagg
    33781 gaattgaaga gcatcatccg ctgctggaaa aactggggcc ggaacctctg tcggaagcat
    33841 tttgtgcgga ttatctgtac gaaaggctga aggcgcagaa acgggcggtc aaacttgccc
    33901 tgatggacaa tgcggtcgtg gtcggtgtgg gcaatattta tgccaatgag agcctgttca
    33961 gagcgggcat ttcgccccac cgtcctgcca accgtctgaa aaagaaagag tgcgcgcttt
    34021 tggttgaaac cgtcaaagcg gtgttgcggc gcgccattga aacgggcggc agtaccttga
    34081 gggattttgt ggacagcgac ggcaaaagcg gctacttcca acaggaatat acggtgtacg
    34141 ggcggcacaa tcagccgtgc ccccggtgcg gcggtttggt tgtgaaagaa actttggggc
    34201 agcgcggcac gttttactgc ccgaattgtc agaaataggg cggaaaacgg tttcagacgg
    34261 cattttatcg gtatgccgtc cgaacgtttc aacaacaaac accgattatc gggaaagaat
    34321 tgttcatgtc ttcaaataaa gcttcatttt ttacacgtct gcgccgcttg tgccgcttga
    34381 cggtctggct attcaaaacc ggcaaaaacc tgcgcggtat tgacggcggc tgccccgagt
    34441 cgcgcaatcg ggcggtaatc gagttgggca ggggggctct ggcggctttg gatatcggat
    34501 tggaggtggg caggcccgca cccgaacatc cgaacggtgt cttggttgcc gccaaccacg
    34561 tgtcctggct ggatattttc gcgatgagcg cggtttatcc gagcagcttt atcgccaagc
    34621 aggaaatcaa aagctggccg gtattgggca agatggggca gaacgcggga acggtgttca
    34681 tcaaccgcaa ttcgcggcgc gacatcgaac cgattaaccg cgccgtctgc gaaaccttgc
    34741 aacgcggtca aaacgtcagt tttttccccg aagcacggac ttcttcgggc ttggggattc
    34801 tgccgttcaa agccgcgctg ttccaatccg ccatcgatgc gggggcaaag gttttggcgg
    34861 tcgcgctgcg ttattatgac gaaacgggaa aaaggacggc tcgtccctca tatgccgatg
    34921 tcggtttgcc gacctgtctg tggcgcattg tgtctatgaa aaaattaacg ataaaagtcg
    34981 atttcgtttg cgtggcggat gcggcggaaa gcgaagaccg ttatgcttta aaagataaaa
    35041 tcgaagaaag catccgtgcc gttgtcgccg acgatgcgga tatcgctgtc tgaaaccggt
    35101 tgtcggaatg tggcagtatg attcgctttt gtggatgtat agtggattaa caaaaaccag
    35161 tacagcgttg cctcgcctta gctcaaagag aacgattctc taaggtgctg aagcaccaag
    35221 tgaatcggtt tcgtactatc tgtactgtct gcggcttcgt cgccttgtcc tgatttttgt
    35281 taatccacta tattaaggct gcggcaacgg gaggacctca aacgaaatgg cgtaaggata
    35341 gtttgttgta ttcataaaat atgccgtctg aacctgtgtt cagacggcat attttatatg
    35401 ggattaacgg cggaacctgc tgccgtcgaa atcatcgaaa gcctcataag ccgcctggca
    35461 ttgggttttc tgttccttat aaggcaggga gcggaatgct ttgcgcgcct ttttgttttc
    35521 gcgcaattcc tgcacgttgc cttgcgatcg gtaccacgcg gcacggcgtt ccaaatattt
    35581 cctgcattcg gggtgcagca tctgcttgtt tgccttgcgg atatgtttgg tatggcggtg
    35641 ggcgggttct gacgtaccgg cagcggcagt tgtcgatacc agtcccaata ttgcagacaa
    35701 cagtatggca agcatctttt tgacagatat gacgatcctt tcagtttgtc attccttcca
    35761 gtataggatg gaaggatgga acgggcaaat tgtcggcagt ttcagactca ttcagccgac
    35821 aaaacttgcc gtttgatatg cggattcaaa taacacatta atctcaataa taaatttcaa
    35881 tcggtaagaa aatggaattt gtcggcggcg gcgcggcaaa atcatacttt gcaaaattta
    35941 acaatttgca ggggcagaaa acaggaagct ttcctttttc gtcggaaaat ccttatttca
    36001 ccgccttgta gccggagccg gtcaaaaggc aaaaaattta cccgtttttt atcggtaaag
    36061 aattatcaga taaaacaaat attataggaa aaatacgaca ggcgggtttt atcgcgcatt
    36121 gcctgaaact gaaaaataca accgttgtca agactggaga aaatgccaaa aatccactat
    36181 attgtctgcc ttaatttatt tgaaaagact gtgtcttgaa tatcaagagt ggaagaggaa
    36241 gcgatgaata caccgactga tttgaaagta accaaacgag acggaagatt agaagccatt
    36301 gatttggata agattcaccg tgtcgtcact tgggcggcgg acggattgga aaatgtttcc
    36361 gtgtcgcagg tcgagttgaa atcgcacatc cagttctaca acggcatccg caccgacgac
    36421 atccacgaaa ccatcatcaa agccgctgcc gatttaattt cggaagatac cccggactac
    36481 caataccttg ccgcgcgttt ggcgattttc catcttcgta aaatagccta cggcgagtac
    36541 gagccgccgc acctttacga ccacgttaaa aaacttaccg atgccggaaa atacgacagg
    36601 catatccttg aggattacag ccgcgaagaa tttgacgaac tgaacgccta tatcgaccac
    36661 gaacgcgata tgtccttttc ctatgccgct gtcaaacagc tcgaaggcaa atatctggta
    36721 cagaaccgcg ttacccgcca gatttatgaa acaccgcagt tcttatatgt tctggtggcg
    36781 atgtgtcttt tcagcaaata tcccaaagaa acacgcctcg attacgtcaa acggttttac
    36841 gatgccgttt ccacatttaa agtatcgctg ccgaccccga ttatgagcgg cgtgcgtacg
    36901 cctacgcgcc agttctcaag ctgtgtgctg attgaatgcg acgatagttt ggattccatc
    36961 aatgccacta ctagcgcgat tgtgaaatac gtttcccagc gtgcgggcat cggcatcaat
    37021 gccggacgta tccgcggttt ggacagcgaa atccggggcg gcgaagcgcg gcataccggc
    37081 tgcattccgt ttttcaaaat gtttcaggcg gcggtcaaat cctgttcgca aggcggcgtg
    37141 cgcggcggag cggcaacttt gttctacccc ttgtggcata tcgaagccga aagcctgctg
    37201 gtgttgaaaa acaaccgcgg tgtggaagac aaccgtatcc gtcagcttga ttacggcgtg
    37261 caaatcaacc gcctgctgta cacccgcctg attaagggcg gcaacattac gctgttttcg
    37321 cccaacgagg ttccgggatt gtacgaagcg ttttttgccg accaagacga atttgagcgg
    37381 ctctatacga aatacgagca agaccctgat atccgcaagc gcatcattcc ggctgccgac
    37441 ctgttttcca cgctgatgca ggagcgtgcc ggaaccgggc gcatctacat tcaaaacgtc
    37501 gatcactgca atacgcacag cccgttcgat ccgcgcgtcg cgcctgttca tcagtccaac
    37561 ttgtgtatgg aaatcgcgct gccgaccaaa cctttggaca atatcaacga cccgaacggc
    37621 gaaatcgccc tgtgtaccct gtctgccttc aacttggggg cattaaacag cttggacgaa
    37681 ttggaagggc ttgccgattt gaccgtgcgc gcgctcgatg cacttttaga ttatcaggga
    37741 tatccggtag aagccgcgcg tacctccact atgggccgcc gttcgctcgg tatcggcgtg
    37801 atcaactatg cgtattattt ggcgaaaaac ggtgtccgct acagcgacgg ctccgcgctc
    37861 ggtctgaccc accgtacctt tgaagccata cagtattacc tgctcaaagc atcggcaaac
    37921 cttgccaaag aatacggtgc gtgcacgctc tttaaccaaa ccgtttattc gcaaggcaaa
    37981 ctgcccatcg acacctacaa aaaagacttg gacgctgtgt gtaacgagcc tttgcactac
    38041 gattgggaaa gcctgcgtgc cgacatcgtc aaatacggcc tgcgtaactc tactctaacc
    38101 gcactcatgc cgtctgaaac cagttcgcaa atcgccaacg ccaccaacgg tatcgagccg
    38161 ccgcgcggat tggtaacggt caaagcatcg aaagacggca ttttgaaaca agtcgtgccg
    38221 gagtttgaaa ccctgaaaaa tgcctatgaa accctgtggc agcttcccgg caacgaaggc
    38281 tatctgaaac ttgttggcgt gatgcaaaaa ttcgtcgatc aggcgatttc cgccaacacc
    38341 gcctacgacc cgggcaaatt cgaaggcggc aaagtttcta tgaaacaaat gctcaaagac
    38401 ctgctgaccg cctacaaata cggcgtcaaa accctgtact accataacac ccgcgacggc
    38461 gcggacgata cgcagaccga tattcaggat gacggctgcg cgggcggggc ttgtaagatt
    38521 tgatgaaagg gggagttttc agatggcctt tagattaata aatcatctga aatataaaat
    38581 atgaaaaata aaatacaaaa tcaattagat aatatagtta ccttaaataa tgagaaattt
    38641 acttttattg atttatttgc gggaataggt ggttttcgca ttgcaatgga gaatgttggt
    38701 gggcgatgtg tattttctag tgaatgggat gataaagccc gtcaaaccta ccaagtaaat
    38761 tttaatgata ttccttatgg agatattaca ttaaaggaaa ccaaagcagc tattccaagt
    38821 aagtttgatg tattaacagc aggattcccg tgtcagccat tctctatagc tggtgtttca
    38881 aagaaaaaaa gcctaggacg agaaacaggc ttcttagata aggcgcaggg aactctattt
    38941 tttgatgttg ctgaaattat tggaaaacat cgacctaaaa tttttctttt agagaatgtg
    39001 aaaaaccttg tttcgcatga caaaggaaat acatttaaag taattaaagg gactttagaa
    39061 gagcttgact atcagatatt ttatcaagtt atgaatgcaa aatattatgt tcctcaaaat
    39121 agggagcgta tttttattgt aggttttgat agacaatatt ttaataagga aataaatttc
    39181 aattttcctt ccccaccaga atcacaacca aaattaaagc aaattttgga agatgatgta
    39241 gataattctt ttactctttc tgataactta tggctttacc ttcaaaatta cgctaaaaaa
    39301 cataaggcaa agggtaatgg atttggtttt ggattagttg atttagatgg aatatcacga
    39361 actctatctg cacgatatta caaagatggt tccgaaatac tcatccctca gaaaggaaaa
    39421 aatcctagga agctgacacc tagggagtgc tcgcgtttaa tgggatttcc taaagatttt
    39481 gttattgatg cagtatccaa gacagctgca tacaagcagt ttggcaattc aattgctgta
    39541 ccgttggttc aagctattgc taaacaaatt ataaatgagt taaaaaatga atgacttggc
    39601 agctcagaca atacaagtag taaataaatc cgatgactta gtagcttcag caatacagac
    39661 agcaaataaa tcaattgcag tatactgtcg ttatattcgt cccaatgatg ttggtactac
    39721 tggtagtcac caatcaggat tttatattca aaaacatttt tcagacgacc tctttgatgt
    39781 agtttgccaa aagggaacaa ataaaactat ttcaatcaaa attaattggc aagatggaag
    39841 cgtcactaat agcaatttta aatattacgg ccaaggcacg agaaatgagg cgagaattac
    39901 gggttttggc aagaattttg aatttttaag tgataaatat agtggttcct tattggtatt
    39961 gtgcagagct tgttataaag atttattatt ccatgctttt gttttatctt cagatgaaga
    40021 tattgaaata tttatcgcag aaactaacat tttaccagga agtttatatt tacctaaaaa
    40081 acaagaagta gaggataacc taacaaaatt attttcacta tttcctaact tccccaaaac
    40141 tgaagaaatg gcagttttgg caagggaaaa tattgcatta aataaaacta acgttagtaa
    40201 tgtgttaaaa caatgggttt caaaggaata tgaattattt tccatttttg aaaaacgtga
    40261 atttgaaatt attaaatcaa aaattactga tttggatagc ttcattaatt ttgcacattc
    40321 ttttacaaat cgcagaaaag caagagcagg aaaatcttta gagttacatt tatcaagaat
    40381 atttgacgaa ttttccttaa aatttgagac gcaagcgaag acagaaggga aaaagaaacc
    40441 agatttttta tttcctggaa gtgaagagta ccatgcgatg gatgaatcag ggaatttcat
    40501 atttcaaact gaaaagctga caatgctagg ttcaaagact acttgtaagg atcgctggcg
    40561 ccaagtttta aatgaagcag atcgaattcc tcataagcat ttatttactc tacaagaagg
    40621 tatatctgat actcaaattc aggaaatgag tgatgagaat ttaaccttag ttgtccctaa
    40681 agaatccgta aaaacatttg gaacttttgg gaaaacccat gttttaactt tagaaaattt
    40741 tattaaatat ataaagtctc agcaggttag ttaaaactta cagatcattt ttaattaata
    40801 tagagaatag attatgtcct gcgaacactt aactatgtca tacagcacct ttcccaaaac
    40861 caaaaacgac gcgctgaatg agccgatgtt tttcggtcag ccggttaatg tcgcccgtta
    40921 tgaccagcag aaatacgagg tatttgaaaa actgattgaa aaacaattgt cgtttttttg
    40981 gcggccggaa gaaatcgacg tgtcgcgcga ccgtatcgac tacgccaacc tgccagaaca
    41041 cgaaaaacat attttcatca gcaatctgaa ataccaaaca ctgctcgatt ccatccaagg
    41101 gcgcagtccg aatgttgcct tgctgccttt ggtttcgatt cccgagttgg aaacgtggat
    41161 tgaaacgtgg agcttcagcg aaaccataca ctcgcgcagc tatacccaca tcatccgcaa
    41221 tattgtgaat gatccgtcgg tcgtgtttga tgatattgtc gaaaacgaat acattaccgc
    41281 ccgcgccgaa gacattgcct gctattacga cgacttaatc gaatacaccc agtattacaa
    41341 tctgttgggc gaaggggtgc acaatgtcgg cggaaaaccc attactgtgt ctttgcgcgg
    41401 gttgaagaaa aaactctatc tctgcctgat gtgcgtcaac gtgttggaag ccatccgttt
    41461 ctacgtttca ttcgcctgct cgtttgcttt tgccgagcgc gagttgatgg aaggcaacgc
    41521 caaaatcatc aaactgattg cccgcgacga agccctgcac ctgaccggca cgcagcatat
    41581 gcttaatctg atgcgttcgg gtgtcgatga ttctgaaatg gcagaaattg ccgctgagtt
    41641 gcaggacgaa tgtttccaac tcttcaaaaa agcggcggaa caggaaaaag aatgggcggc
    41701 atatttgttt aaagacggtt cgatgattgg tttgaacaaa gaaatcttat cccagtacgt
    41761 cgaatatatt accaatctgc gtatgcaggc ggtggggttg ccggccggat ttgaaggcgc
    41821 aaatcaaaac ccgattccgt ggattaatgc gtggctgtcg tccgataacg tacaggtcgc
    41881 gccgcaggaa gtggaaatat cctcttattt gatcggtcag atcgattctg aagtgaatac
    41941 ggatgatttg ggcgattttg agttgtaaac gttttttgaa aaaatgccgt ctgaagccgg
    42001 atgtttcaga cggcatttgt atgttgtatg atgggaaaaa cagcgggtag gatcggttat
    42061 tgttcctttt atagtggatt atagtggatt aacaaaaatc cggacaaggc gaggcaacgc
    42121 cgtactggtt taaatttaat ccactatatt tttgattggt cggaaatggc gcgcattggt
    42181 acgaataagg gtttttttga gctcttggag ggcgagaccc tgttggaagg cttggaacgg
    42241 acggggcata tggtggaata tcagtgccga agcggatatt gcggatcgtg ccgagtgaag
    42301 attttggagg gaagcgttac ttatcgggag ccgcctttgg cttttttggg gcgggacgag
    42361 atactgccgt gctgctgtta cgtcgagggg gatgtcaggc tggattgcgg tttgtcgggg
    42421 gaggatgagg ggctgtctga cagtttgttg aaataaaagc cgtccgaaca ttggttcgga
    42481 cggctttttg acggtattac cggttatgcc tgatgagtcg gtaaaaggtt tcaccgtctt
    42541 ggatataacc cagttctacc cgggcgattt ccgaaatggc ttcttgaccg ttttccaaat
    42601 catagacttc ggcggcaagg gaatgattgc gtagggcgag tgtctggttt ttttcttctt
    42661 gaacggcaat ctgttctctc agactgctgt tgcgtccgat gctgcctttg ccgaaccaga
    42721 ggctgtattg gcaacagaca agtgcgaagg ataaaacgac agttacccac ttcatacctt
    42781 aaccttttct tatttgccca gttggtagaa tgcggctttg ctggggtagt cggcggcttc
    42841 cgccaattct tcctcgatac gcagcagttg gttgtatttc gccatgcggt cggaacggct
    42901 caaagaaccg gttttgatct gcatacagtt ggtggcgact gccaagtcgg caatggtgct
    42961 gtcttcggtt tcgccggagc ggtggctcat tacgctggcg tagcggttgc gtttggctaa
    43021 gtcgacggct ttcagggttt cactcaaagt accgatttgg ttgactttga ccaatagtgc
    43081 gtttgccacg cctttttcaa tgccttcggc aaggattttc gggttggtaa cgaagaggtc
    43141 gtcgccaacg agttggactt tgccgcccag tttttcggtc agcagtttcc agccttccca
    43201 gtcgttttca tccatcccgt cttcgatgga gatgatgggg aactcgttga ccaggccttc
    43261 cagatattcg gcaaattccg cgttggtgta ggagcggcct tcggcttcca agtggtattt
    43321 gccgtctttg tagaactcgc tggacgcgca gtccaatgcg aataatacgt cttcgcccgc
    43381 tttgtagccg gcggcttcgg tcgcctcgac catcagttgc agggcttctt tgtggctgtt
    43441 caggttgggg gcgaaaccgc cttcgtcgcc gactgtggtc gggaagcctt tgctgtcgca
    43501 cagttttttc aaggcgtgga aaatttccgc accgcagcgc aacgcttcgc ggaaagattt
    43561 tgcgccgacg ggcataatca taaactcttg gatgttcagg ctgttgttgg cgtgttcgcc
    43621 gccgttgatg acgttcatca tcggtacggg cagggacatc gggcctgcgc cgcccaagta
    43681 gcggtaaagc ggcaggcctg agtcttcggc agcggcgcgt gcaaccgcca tagaaaccgc
    43741 caaagtcgca ttcgcaccca aattgccttt gttttcagta ccgtccaatt cgatcatgat
    43801 ttggtcgata taagattgct cgttggcatc gataccaatg agggcttggg cgatttggtt
    43861 gttgacgtgt tcgaccgcct tcaatacgcc cttgcccgaa taacgggatt tgtcgccgtc
    43921 gcgaagttcc aaagcctctt tttgaccggt ggacgcgccg ctcggtacgg ctgcgcgtcc
    43981 cattacgccg gattcgagca atacatcaca ctcgactgtg gggttgccgc gtgagtccaa
    44041 aatttcgcgg gcgaaaatat caacgattgc gctcatgaat gttctccaag tgaagtgaag
    44101 ggaggtaaaa aatgggaggg cttcagacgg catctttgcc ggaaagccgc caacttaaaa
    44161 ctgctgaaag tagggcggtt gccataaaaa caatactgga aatgccgtgc cacattccga
    44221 aggatccgcc tacaaacgac aacagccaat tttcatgtcc gtatttcagt gcctcgataa
    44281 cgggtgtaat caagaatcgg ttggcggcaa gggcggacaa taaaaaaagc agcagggcgg
    44341 tttgccgccg ggttagggcg gcaaaggcgg cagccagtac cgcgccccaa acggcaagcc
    44401 cgctccaaga gaggatgtcg aacaatacgc cggcaatttc gcccgcctgc attttgggca
    44461 gcattttgaa cagcaccggc gcgacgatat aacccgccat aatctgcata ccgagccaca
    44521 aggttgcggc ataccggctg atttttcgga aagtctgcat cataaggcga aaccgtgtta
    44581 ctcgattgtt aaaatcggtt gtgatttgat taaatcgtcc aatgctttga tgcggattaa
    44641 aaaatcttct aaaaggtgca gcggcagcgc gctggggccg tcgcattttg ccagtttcgg
    44701 atcggggtgc gattcgagga acagaccggc aaggcgggtt gccatgcctg caagtgccaa
    44761 atccaaagcc tgtgcgcgac gaccgccgga tgcggcagaa ccagcatcgc gggtttgcag
    44821 ggaatgggta acgtcgaaaa taaccggcag gttgccgcag gtttgtttca tcacgcagaa
    44881 accgagcata tcgacaacga ggttgtcgta gccgaagctg ctgccgcgtt cgcataaaat
    44941 cagtttcccg ttgccggctt cgtggaattt ttccacaatg tttttcattt gagaggggct
    45001 gaggaactga ggttttttga tgttgacgac gttgccagtt tttgccatgg caaccactaa
    45061 atcggtctgc cgcgcaagaa aggcgggaag ctggatgaca tcgcacactt cggcgacggg
    45121 ttggcactga tggggttcgt gtacgtcggt aatgacgggg atgccgaact ctgctttgac
    45181 tttttcaaaa atctttaagc cttcttccaa gcctacgccg cgataagaat ggatggagga
    45241 acggtttgcc ttgtcgaaag aggctttaaa gatataggga attccgagtt tgcgggttac
    45301 ttcgacgtaa tgcgcgcagg tttggagggt ggaatccaag ctttccaaaa cgttgatgcc
    45361 gccgaatagg acgaagggcg agttgttgcc gatggtgatg tcgttgattt taatatccat
    45421 aatcgatgtc cgtttgcgga attacagcac ggtgtgcggc ggctcgtagg agatgatgtc
    45481 gcggattttg ttgttcccgt ccactaagac gactttgggt tcatgcgcgg cgatttcggg
    45541 ttcggagagt tggacgtaag acatgatgat gacgatatcg cctttctgca ccagccttgc
    45601 cgcagcaccg ttcagacaaa tcacgccgct gccgcgttta cctgaaatgg tataggtttc
    45661 aaaacgttcg ccgttgttgt tgttgacgat ggcgactttt tcgttggggt agatgcctgc
    45721 cgcgtctaac agatcttgat cgacggtaat gctgccgacg tagttcaaat cggcttcggt
    45781 tacggtggcg cggtggattt ttccgccaag catagtacgg aacatgtatt tccttttggt
    45841 ttgtgtgcgg tctgacgggc gcgatgccgt ctggaaatct gaatgccgta ttatagtgga
    45901 gtttccttca aattcataat ggcggctttc ggacaaggaa aacggtgttt cagacggcat
    45961 tgcggtgtcg gctttatttg ggcaggcatc tgttttgcaa ggtttttaaa acgtttttta
    46021 cggtgttgat tctgacctcg atattttcca tctctgcggt aaaccgcagc ttatcggcgc
    46081 cggcaaggcg gtattttttg tcgttctgaa tcagcaggat gatttcggtt ggatcgacat
    46141 tgtggttttt gccgaaggtt accgttaccg attcgccggt cgcatcgatg gcatcaatac
    46201 ccaattcttt tgccgcaagc cgtaagtggt ggctttcgat gagggttttg acgggttgtt
    46261 cgggcaggcc gaagcggtcg acgagttctt cgtgtatggc gttgatttgc tgcacggttt
    46321 cgcagacggc gaggcgtttg tagaggacga gacgctcgtg gatgtcgggg cagtagcttt
    46381 cgggcagtag ggcggggctg tgcagtttga tttcggtggt aatgcccaat ggcgcgtcga
    46441 ggtcgggctg gcggcctttt ttgaggtcgc gcacggcttg tttgagcatt tcggtgtaga
    46501 gcgtgaagcc gacctgtatc atttcgccgg actgcccttc gccgaggatt tcgcctgcgc
    46561 cgcggatttc caaatcctgc atggcgaggg tgaaacctgc gccgagttcg tctgctgccg
    46621 cgatggcgtc gaggcgtttt tctgcgtctt tggtgatgta ttcgggcgtg agcaggtagg
    46681 cgtaggcttg gtgatggctg cggccgacgc gcccgcgaag ttggtgcagt tgcgccagcc
    46741 cgaatttgtc ggcgcggttg atgatgatgg tgttggcgtt ggggatgtcg atgccggttt
    46801 cgatgatggt ggaacagagc aacacgttga atcgttgctg taaaaagtcg cgcatgactt
    46861 gttccaactc gcgctcgcgc agttgtccgt gcgctacgcc gatgcgggct tcgggcagca
    46921 gggtttccag ccgctcgcgc atattttcaa tcgtatctac ttcattgtgc aggaaaaata
    46981 cttgcccgcc gcgtttgagt tcgcgcaaca cggcttcgcg cacgctgcct tcgctgaagg
    47041 gtttgacaaa ggttttgacg gcgaggcggc ggctcggtgc agtggtaatc agcgagaagt
    47101 cgcgcagacc ttccaacgcc atacttaaag tacgcggaat cggcgtggcg gtcatggtga
    47161 ggatatcgac attggcgcgc aggcgtttga gctgctcttt ctgtcgcacg ccgaagcggt
    47221 gttcttcgtc gataatcact aaacctaagt ttttgaattt tatgtcgtcc tgcaccaatt
    47281 tgtgcgtgcc gataatgata tcgaccgtgc cgtccgccat gccttcgagc gcggctttgg
    47341 tggctttgct gttgttgaaa cgcgaaaggc cggcgacttt cacgggaaaa tcggcgaaac
    47401 ggtcggcaaa gttttgcgcg tgctgctcga ccagaagcgt ggttggggcg agtacggcga
    47461 cctgtttgcc acccatcacc gccacaaacg cggcgcgcag ggcgacttcg gttttgccga
    47521 aaccgacatc gccgcacaca aggcggtcca tcggcttcgc ctgcgtcaag tctttaatca
    47581 cggcggcaat ggcggctgcc tggtcttcgg tttcctcgta gccgaagccg tcggcaaacg
    47641 cctgataatc caactcgttg atttcaaact tgtgtcccga ttgggcggcg cgttgggcat
    47701 agagattgag caactcggcg gcggtatcgc gcgctttttc ggcagccttg cgttttgcct
    47761 tgttccacgc gccgctgccg agcttgtgca gggcaatgtt ttcatgcgcc tgaccggagt
    47821 agcggctgat taaatgcagt tgcgaaacag ggacataaag ctgcgcttcg cctgcgtatt
    47881 cgagcaacat catttcgttg gtttcgccgc ccaagtccat cgttaccaag cccatatacc
    47941 gcccgatgcc gtgttcttcg tgcacgacgg gatcgccgat gttgatttcg gcaaggtcgc
    48001 gcaacaggcc atctgaaacg gcggcgtgtt tcttgcgatg atatttgcgc gagcgggcaa
    48061 catattgata caaatcggat tcggtaatga cagcgatggc t
//
LOCUS       DAXIDM010000002        47272 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000002 DAXIDM010000000
VERSION     DAXIDM010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 47272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47272
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.002"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(65..1312)
                     /gene="fabF"
                     /locus_tag="ACFOAE_000048"
     CDS             complement(65..1312)
                     /gene="fabF"
                     /locus_tag="ACFOAE_000048"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFC6883628.1"
                     /translation="MSQRRVVITGLGQVSPVGNTVAEAWDTLLAGKSGIGAITRFDAS
                     DINSRVAGEVRGFDIGQYISAKEARRMDVFIHYGIAAALQAIADSGLDDVENLDKDRI
                     GVNIGSGIGGLPSIEVTGKAVIEGGARKINPFFIPGSLINLISGHVTILKGYRGPSYG
                     MVSACTTGAHAIGNSARLIKYGDADIMVAGGAEGAISTLGVGGFAAMKALSTRNDDPA
                     TASRPWDKGRDGFVIGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNE
                     EGPALAVTRALKDAGINPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSST
                     KSMTGHLLGAAGGVEAVYSILAIHDGKIPPTINIFEQDVEAGCDLDYCANEARDAEID
                     VAISNSFGFGGTNGTLVFKRFKG"
     gene            complement(1468..1704)
                     /gene="acpP"
                     /locus_tag="ACFOAE_000049"
     CDS             complement(1468..1704)
                     /gene="acpP"
                     /locus_tag="ACFOAE_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFC6883629.1"
                     /translation="MSNIEQQVKKIVAEQLGVNEADVKNESSFQDDLGADSLDTVELV
                     MALEEAFGCEIPDEDAEKITTVQLAIDYINAHNG"
     gene            1936..2943
                     /locus_tag="ACFOAE_000050"
     CDS             1936..2943
                     /locus_tag="ACFOAE_000050"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006222 - UMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HFC6883630.1"
                     /translation="MYPLARRILFALDAEKAHHFTLDALYTVYKLGLIPVTGNRTKPV
                     KLMGMDLPNPVGLAAGLDKNGEYIDALGALGFGFIEIGTVTPKPQPGNPQPRLFRVPE
                     HQGIINRMGFNNHGIDTMIRNIEKSKFSGVLGINIGKNAVTPIENAADDYLICLEKAY
                     AHASYITVNISSPNTKNLRALQGGDELSALLEALKNKQAQLASVYGKYVPLAVKIAPD
                     LDEAQIEDIAHVVKSVEMDGIIATNTTIDKSSLGSHPLAGEQGGLSGLPVHEKSNRVL
                     KLLADHIDGKLPIIGVGGIMEGGDSADKIRLGATAVQVYSGLIYKGPALVKECLKALA
                     R"
     gene            2959..3138
                     /locus_tag="ACFOAE_000051"
     CDS             2959..3138
                     /locus_tag="ACFOAE_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883631.1"
                     /translation="MPSKRTFCRSDGIFISFFRLPPLENPLRAALFETKQTPAANRTI
                     LIRSQSKSGGKLLNI"
     gene            3276..3599
                     /locus_tag="ACFOAE_000052"
     CDS             3276..3599
                     /locus_tag="ACFOAE_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883632.1"
                     /translation="MFKDELNEFIRLISDPESELDEWYLSDFKDEHIWEMQSYEAFSC
                     LREAVPYLFAYPRYGYELLEIISALKETSDTTELFYEPGIVPLLIDLYKEDSYLVNMV
                     KRIFK"
     gene            3686..3967
                     /locus_tag="ACFOAE_000053"
     CDS             3686..3967
                     /locus_tag="ACFOAE_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883633.1"
                     /translation="MENGQRNNRFSLEKRIFYLEHSGRYLMICALSDYSQNKHTVVMA
                     NFIYPDEKTDWRNLDDLFNELVLEELQASFMDWHPTVEEAISRHLEDFS"
     gene            4020..4493
                     /locus_tag="ACFOAE_000054"
     CDS             4020..4493
                     /locus_tag="ACFOAE_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2247 family protein"
                     /protein_id="HFC6883634.1"
                     /translation="MNLDLTAQKVRLSWKDILWGYGNKYLGWADVAAYARKMTLSDHD
                     ERVFKLSLINKSNILELKPVLEDLASEMRDYSPKNWLYVLLSDVFHRKEEFEDPLGEV
                     EKIYADFDYPEEIESFVRYMPPKDGYIPSAHTYEENIARLYSHWEHYLNNGGGQG"
     gene            4507..4812
                     /locus_tag="ACFOAE_000055"
     CDS             4507..4812
                     /locus_tag="ACFOAE_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883635.1"
                     /translation="MPSEALSGLQTAFCFPTVYKLSLFLDRNNDLIYLKRLEDMIMGF
                     WNGVAKAVGEGMIEAGNEHKALKMEYAEKSSEELHEIVKSDGFLKIPHGRKVRLMLF"
     gene            5030..7720
                     /gene="glnE"
                     /locus_tag="ACFOAE_000056"
     CDS             5030..7720
                     /gene="glnE"
                     /locus_tag="ACFOAE_000056"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008882 - [glutamate-ammonia-ligase]
                     adenylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HFC6883636.1"
                     /translation="MSDNRLDTARRHSLFLARQLDNGKLKPEIFLPMLDKVWTEADFQ
                     AFADWDKIRAEENEEELARQLRGLRRYVVSQIIVRDINRISDLNEVTRTITLFADFAV
                     NTALDFAYAYYRDMYGTPIGRYTKSPQHLSVVAMGKAGGYELNVSSDIDLIFIYPESG
                     DTDGRRERGNQEFFTKVGQKLIALLNDITADGQVFRVDMRLRPDGDSGALVLSETALE
                     QYLITQGREWERYAWCKGRVVTPYPNGIKSLVRPFVFRKYLDYGAYEAMRKLHRQICS
                     EVSKKGMADNIKLGAGGIREVEFIAQIFQMIRGGQMRALQLKGTQETLKKLAETGIMP
                     SENVETLLAAYRFLRDVEHRLQYWDDQQTQTLPASPEQQQLLAESMGFDSYAAFSDDL
                     NAHRTKVNQLFNEILSEPEEQTQSNGEWQWVWQEKPDEEGRQCRLKEHGFDAETIATR
                     LDQIRHGHKYRHLSAHAQPRFDAVVPLFVQAAAAQSNPTDTLMRLFDFLENISRRSAY
                     LAFLNEHPQTLAQLAEIMSQSSWVAAYLNKYPILLDELISAQLLDTAFDWQALAATLS
                     DGIEACGGDTEAQMDTLRRFQHAQVFRLAVQDLAGLWTVESLSDQLSALADTILAAAL
                     LCAWADMPKKHRDTPQFAVVGYGKLGGKELGYASDLDLVYLYDDPHPDAGDVYSRLAR
                     RLTNWLSAATGAGSLYETDLRLRPNGDAGFLAHSIAAFEKYQRENAWTWEHQSLTRAR
                     FICGTPEIQTAFDRIRTEILTAERDQTALSGEIIEMREKMFPTHPPADSNVKYARGGV
                     VDVEFIVQYLILAHARKYPQLLDNYGNIALLNIAADCGLIDKTLAGQSRTAYRFYRRQ
                     QHNTKLRDAAKTEVTGELLAHYGNVRKLWREVFGEEAATA"
     gene            complement(8020..8712)
                     /locus_tag="ACFOAE_000057"
     CDS             complement(8020..8712)
                     /locus_tag="ACFOAE_000057"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HFC6883637.1"
                     /translation="MKRFTYTLSDGLCIEIELKRSAKKNLILRPVNMQTVSINVPPFF
                     QDHALANWLAANETILRNTLAKTPVHPVSHPNLPEWIWYRGIKTKLDTHSQSHIRITS
                     SEILLPRKETAAQIDHLRRLLNERAREYLLPRLEKHAAETGLTPTATDLSNAKTFWGV
                     CRPHTGIRLNWRLIGTPEYVADYVCIHELCHLRHPDHSPRFWHLVNTLTPHTDNAKSW
                     LKAHGRELFVLG"
     gene            complement(8820..10013)
                     /locus_tag="ACFOAE_000058"
     CDS             complement(8820..10013)
                     /locus_tag="ACFOAE_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFC6883638.1"
                     /translation="MSDQKNRRNALIGAAFLMATSAIGPGFLTQTATFTQALAASFGF
                     VILLSILLDIGAQLNIWRIVAVSEKQAQDIANQVLPGAGYFLAVLIVMGGLAFNIGNV
                     GGAGLGLNLLTGLSPETGAVISGVIAIGVFLFKEAGKVMDKFAQVMGFVMIALTVYVA
                     WQANPPLADAAVHTFMPEKLDAMAIVTLVGGTVGGYITFAGAHRLLDAGIKGKSALPE
                     VSQSSVRAILIASIMRIVLFLAVLGVVSQGVQLNPDNPASTPFEYAAGYIGLLIFGVV
                     IWAASITSVIGAAYTSVSFFSGLSPSIERNKNKWIIAFIAVSTAVFSTIGKPAQVLVF
                     VGALNGLILPISLGLILIAAYKTKIVGDYKHPLWLTVSGVIVVGLMAVLSAITISKYI
                     GGLFG"
     gene            complement(10142..10879)
                     /gene="pxpA"
                     /locus_tag="ACFOAE_000059"
     CDS             complement(10142..10879)
                     /gene="pxpA"
                     /locus_tag="ACFOAE_000059"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HFC6883639.1"
                     /translation="MKQVDLNADLAEGCGSDEALLQLITSANIACAQHAGSIADIRAA
                     LAYAQQNGVRIGAHPGYPDRENFGRTEMNLSEADLRACLNYQLGALQALCRDQGLEMA
                     YVKPHGAMYNQAAKNRALADTVARIVADFDPKLKLMALSGSLLLEAGKAAGLGVISEV
                     FADRRYMPDGTLVPRSRPDAQVDSDEEAIAQVLQMVRDGRVKAVNGSLVAVQADSICL
                     HGDGPHAVVFAEKIRQELLAAGIKVSA"
     gene            complement(10866..11795)
                     /locus_tag="ACFOAE_000060"
     CDS             complement(10866..11795)
                     /locus_tag="ACFOAE_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HFC6883640.1"
                     /translation="MIHVSAVQAPAHIQDTGRYGHRRYGIGHAGAMDTVALAAGNILL
                     GNDEGTAAIEIALGGIMLVFERDTPFCLTGAVYQAELDGEPVYSYWRYTARKGQTLKM
                     VRAVQGMYGYVCVAGGFDVPEVMGSRSTDLKAGFGGHQGRMLQKGDYLPIGKGAQELS
                     KVGIAPIPFTDTVHLVPSSEYAAFSEKGRLNLERETWTLQSDSNRMGYRFDGQPLTLS
                     QPLEMLSHAVQAGTVQVPPGGKPIILLADAQTTGGYPKIATVAAADLGRLAQVRFGSK
                     VKFKIIGLKEATALRRKNQVYLNQIRRITHEAG"
     gene            complement(11792..12439)
                     /gene="pxpB"
                     /locus_tag="ACFOAE_000061"
     CDS             complement(11792..12439)
                     /gene="pxpB"
                     /locus_tag="ACFOAE_000061"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing)
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HFC6883641.1"
                     /translation="MRIEITPISESALVCRLNAPSELGKQQKLWAFAAALGQHDRIEE
                     VVVGMNNLTVFTRFDTDLATLADELQYVWEHTAVTDHQGKLVEIPVCYGGEYGPDLAE
                     VAAFHQTVISEIVRRHTAQTYTVFMMGFQPGFPYLGGLPEALHTPRRAVPRTSVPAGS
                     VGIGGSQTGVYPFASPGGWQIIGRTELPLFRADLNPPTLLAAGDQVRFVAERIEP"
     gene            12623..14830
                     /gene="uvrD"
                     /locus_tag="ACFOAE_000062"
     CDS             12623..14830
                     /gene="uvrD"
                     /locus_tag="ACFOAE_000062"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HFC6883642.1"
                     /translation="MFPDQSAPNLLQGLNPEQLSAVTWPPQSALVLAGAGSGKTRVLT
                     TRIAWLLQTGQASVHSIMAVTFTNKAAKEMQTRLGAMIPVNVRAMWLGTFHGLCHRFL
                     RLHHRDAGLPSSFQILDSGDQLSLIKRLLKSLNIAEEIIAPRSLQGFINAQKESGLRA
                     SVLSAPDPHTSRMIECYAEYDKICQREGVVDFAELMLRSYEMLQSNEILRQHYQNRFN
                     HILVDEFQDTNKLQYAWLKLMAGGNAAVFAVGDDDQSIYRFRGANVGNMTALMEEFHI
                     DAPVKLEQNYRSVGNILAAANAVIENNDERLGKNLRTDAEAGDKIRYYSAFTDLEEAR
                     FIVDETKALEREGWDLDEIAVLYRSNAQSRVIEQSLFRSGIPYKIYGGLRFYERQEIK
                     HALAYLRLAVNPDDDNALLRVINFPPRGIGARTVENLQTASNEQGITLWQAACNAGAK
                     AAKIAAFVRLIEALRNQVGQLPLSEIIVGILKDSGLTEHYRTQKGDNQDRLDNLDELV
                     NAAIEFKPEDSNFETLPENISDDPAFPILAFLSNAALESGENQAGAGEKAVQLMTVHA
                     AKGLEFNAVFLTGMEEGRFPSEMSLAERGGLEEERRLMYVAITRARKRLYITMAQQRM
                     LHGQTQFGIVSRFVEEIPPEVLHYLSVKKPAYDSYGNTRQTATFKDKIIDDYKQPQTY
                     AGFRIGQNVRHAKFGTGVIIDAADKGESARLTINFGKQGVKELDTKFAKLEAM"
     gene            15187..15726
                     /locus_tag="ACFOAE_000063"
     CDS             15187..15726
                     /locus_tag="ACFOAE_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC6883643.1"
                     /translation="MSQVFKDFDLSSVWESDSWADENYKEAPFTPEILAAVESELGYK
                     LPQSFIELMAVQNGGIFVKNCFPTTQRNSWAKDHVQICEVSGIGFEKEGSLCGETGQK
                     LWMEEWEYPPIGVYFANDPSGGHAMFALDYRECGKDGEPKVVFVEQESDFEIVELAPD
                     FETFIRSLRHEDEFIDEEI"
     gene            complement(15916..16131)
                     /locus_tag="ACFOAE_000064"
     CDS             complement(15916..16131)
                     /locus_tag="ACFOAE_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883644.1"
                     /translation="MNIINYTGDDIIISLTREELQLLRSLVIEIYAGVCIDAEEFEIV
                     SGIRNSKLVQELEQQLIEAYDLMDTKG"
     gene            complement(16255..16614)
                     /locus_tag="ACFOAE_000065"
     CDS             complement(16255..16614)
                     /locus_tag="ACFOAE_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 8 family protein"
                     /protein_id="HFC6883645.1"
                     /translation="MIKLDLKSINLYDIDFEKFTPEIPDNFHRWIDLDIGIEGEQGSS
                     IFSLCICSPKWISHHCNKEGFFWSNALILEQFDHKIIKSEIDKILEYCSKETWDLTLS
                     NLLRFFSWEFEDYNPNT"
     gene            16667..17044
                     /locus_tag="ACFOAE_000066"
     CDS             16667..17044
                     /locus_tag="ACFOAE_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060537127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6883646.1"
                     /translation="MRKSRLSRYKQNKLIELFVAGVTARTATEPDSIVYTDCYRSYDV
                     LDVSEFSHFRINHSTHFAERQNHINGIENFWNRAKRHLRKFNGIPKAHFELYLKECEW
                     RFNNSEIKVQISILKQLVKSSLS"
     gene            17243..17863
                     /locus_tag="ACFOAE_000067"
     CDS             17243..17863
                     /locus_tag="ACFOAE_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused MFS/spermidine synthase"
                     /protein_id="HFC6883647.1"
                     /translation="MNSTASKTLKGLSLVFFASGFCALIYQVSWQRLLFSHIGIDLSS
                     ITVIISVFMVGLGVGAYFGGRIADRFPSSIIPLFCIAEVSIGLFGLVSRGLISGLGHL
                     LVEADLPIIAAANFLLLLLPTFMMGATLPLLTCFFNRKIHNVGESIGTLYFFNTLGAA
                     LGSLAAAEFFYVFFTLSQTIALTACFNLLIAASVWLRYRKDGYSEH"
     gene            17886..19337
                     /locus_tag="ACFOAE_000068"
     CDS             17886..19337
                     /locus_tag="ACFOAE_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine synthase"
                     /protein_id="HFC6883648.1"
                     /translation="MLSFLSGLLSLGIEVLWVRMFSFAAQSVPQAFSFTLACFLTGIA
                     VGAYFGKRICRSRFVDIPFIGQCFLWAGIADFLILGAAWLLTGFSGFVHHAGIFITLS
                     AVVRGLIFPLVHHVGTDGNKSGRQVSNVYFANVAGSALGPVLIGFVILDFLSTQQIYL
                     LICLISAAVPLFCTLFQKSLRLNAVSVAVSLMFGILMFLLPDSVFQNIADRPDRLIEN
                     KHGIVAVYHRDGDKVVYGANVYDGAYNTDVFNSVNGIERAYLLPSLKSGIRRIFVVGL
                     STGSWARVLSAIPEMQSMIVAEINPAYRSLIADEPQIAPLLQDKRVEIVLDDGRKWLR
                     RHPDEKFDLILMNTTWYWRAYSTNLLSAEFLKQVQSHLNPDGIVMFNTTHSPHAFATA
                     VHSIPYAYRYGHMVVGSATPVVFPNKELLKQRLSRLIWPESGRHVFDSSTVDAAAQKV
                     VSRMLIQMTEPSAGAEVITDDNMIVEYKYGRGI"
     gene            19799..20155
                     /locus_tag="ACFOAE_000069"
     CDS             19799..20155
                     /locus_tag="ACFOAE_000069"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit A"
                     /protein_id="HFC6883649.1"
                     /translation="MLSAYFPVFVFILVGLAASVLFILLGTILGPKRHYAEKDAPYEC
                     GFEAFENARMKFDVRYYLVAILFILFDLEVAFMLPWAVVFKDLGAYGFWSMLVFIVVL
                     TVGFVYEWKKGALEWE"
     gene            20146..20628
                     /locus_tag="ACFOAE_000070"
     CDS             20146..20628
                     /locus_tag="ACFOAE_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045271 - respiratory chain complex I
                     [Evidence IEA];
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_function: GO:0048038 - quinone binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B family
                     protein"
                     /protein_id="HFC6883650.1"
                     /translation="MGIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMH
                     AGMARYDLDRFGIIFRPSPRQADLMIVAGTLTNKMAPALRRVYDQLAEPRWVLSMGSC
                     ANGGGYYHYSYSVVRGADRVVPVDVYVPGCPPTAEALIYGLIQLQQKIKRTSTIARDE
                     "
     gene            20641..21234
                     /locus_tag="ACFOAE_000071"
     CDS             20641..21234
                     /locus_tag="ACFOAE_000071"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="HFC6883651.1"
                     /translation="MASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYVSVMTT
                     LRDHEELHFELLVDLCGVDYSTYKNEVWQGKRFAVVSQLLSVKNNQRIRVRVWVSDDD
                     FPVVESVVDIYNSADWYEREAFDMYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGY
                     VEMRYDEEQKRVIYQPVTIEPREITPRIVREENYGGQ"
     gene            21224..22480
                     /gene="nuoD"
                     /locus_tag="ACFOAE_000072"
     CDS             21224..22480
                     /gene="nuoD"
                     /locus_tag="ACFOAE_000072"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase (quinone) subunit D"
                     /protein_id="HFC6883652.1"
                     /translation="MANKLRNYTINFGPQHPAAHGVLRMILELEGETIVRADPHIGLL
                     HRGTEKLAETKTYLQALPYMDRLDYVSMMVNEQAYCLAVEKLAGIDVPIRAQYIRVMF
                     AEVTRILNHLMGIGSHAFDIGAMTAILYAFRDREELMDLYEAVSGARMHAAYFRPGGV
                     YRDLPDFMPKYESSKFRNAKVLKQLNESREGTMLDFIDAFCERFPKNIDTLETLLTDN
                     RIWKQRTVGIGVVSPERAMQKGFTGVMLRGSGVEWDVRKTQPYEVYDKMDFDIPVGVN
                     GDCYDRYLCRMEEMRQSVRIIKQCSEWLRVNPGPVITTNHKFAPPKRTEMKTGMEDLI
                     HHFKLFTEGMHVPEGETYTAVEHPKGEFGVYIISDGANKPYRLKIRAPGFAHLQGMDE
                     MAKGHMLADVVAIIGTQDIVFGEVDR"
     gene            22480..22953
                     /gene="nuoE"
                     /locus_tag="ACFOAE_000073"
     CDS             22480..22953
                     /gene="nuoE"
                     /locus_tag="ACFOAE_000073"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HFC6883653.1"
                     /translation="MLSAESLKQIDTELAKYPADQRRSAIMGALRIAQTEKGWLAPET
                     IAFVADYIGITPAQAYEVATFYNMYDLEPVGKYKLTVCTNLPCALRGGMATGEYLKQK
                     LGIGYGETTPDGKFTLVEGECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE"
     gene            23343..24644
                     /gene="nuoF"
                     /locus_tag="ACFOAE_000074"
     CDS             23343..24644
                     /gene="nuoF"
                     /locus_tag="ACFOAE_000074"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HFC6883654.1"
                     /translation="MAIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENIS
                     QTDVIDEVKTSGLRGRGGAGFPTGLKWSFMPRSFPGEKYVVCNTDEGEPGTFKDRDII
                     MFNPHALIEGMIIAGYAMGAKAGYNYIHGEIFEGYQRFEAALEQARAAGFLGKNILGS
                     DFEFELFAHHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTET
                     FSSVSFIIRDGGQAFADKGIPNAGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGG
                     MRGGKKLKAVIPGGSSAPVLPADIMMQTNMDYDSISKAGSMLGSGAIIVMDEDVCMVK
                     ALERLSYFYYDESCGQCTPCREGTGWLYRIVHRIVEGKGKMEDLDLLDSVGNQMAGRT
                     ICALADAAVFPVRSFTKHFRDEFVYYIEHGGPMKEHKWGGW"
     gene            24644..25081
                     /locus_tag="ACFOAE_000075"
     CDS             24644..25081
                     /locus_tag="ACFOAE_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883655.1"
                     /translation="MVEAKIFILYGAANKGKSTTLNTLFNQICWKFSKFLVFFERHGN
                     GLDFVAVFDHEGQRIGFYSSGDNEYEVRRNLYKLYSHNCDFIFGTSRTRGGSCDAVGC
                     YAELLHGDVNIINWCEKFEPTDEDNERAVKELFKSFKNIINEL"
     gene            25369..27630
                     /gene="nuoG"
                     /locus_tag="ACFOAE_000076"
     CDS             25369..27630
                     /gene="nuoG"
                     /locus_tag="ACFOAE_000076"
                     /EC_number="7.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003776117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006120 - mitochondrial electron transport,
                     NADH to ubiquinone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HFC6883656.1"
                     /translation="MLQIEIDGKQVSVEQGATVIEAAHKLGTYIPHFCYHKKLSIAAN
                     CRMCLVNVEKAPKPLPACATPVTDGMIVRTHSAKAREAQEGVMEFLLINHPLDCPTCD
                     QGGECQLQDLAVGYGKTTSRYTEEKRSVVGKDMGPLVSAEEMSRCIHCTRCVRFTEEI
                     AGLQEIAMVNRGEHSEIMPFIGKTVETELSGNVIDLCPVGALTSKPFRFNARTWELNR
                     RKSVSAHDALGSNLIVQTKDHTVRRVLPLENEAINECWLSDRDRFAYEGLYHESRLKN
                     PKIKQGGEWMDVDWKTALEYVRSAIECIAKDGKQNQVGVWANPMNTVEELYLAKKLAD
                     GLGVKNFATRLRQQDKRLSDGLKGAQWLGQSIESLADNDAVLVVGANLRKEQPLLTAR
                     LRRAAKDRMALSVLAGSKEELLMPLLSQEAAHPDEWAGRLKNLSANAEHAVTASLKNA
                     EKAAVILGAEVQNHPDYAAIYAAAQELAAATGAVLGILPQAANSVGADVLGVNSGESV
                     AEMANAPKQAVLLLNVEPEIDTADGAKAVAALKQAKSVMAFTPFVSETLLDVCDVLLP
                     IAPFTETSGSFINMEGRLQSFHGVVQGFGDSRPMWKVLRVLGNLFDLQGFEYHDTAAI
                     LKDALDVESLPSKLDNRNTWTGEGVQTTSDRLVRVGGVGIYHTDSIVRRSAPLQETGH
                     AAVPAARVNPNTLARLGLQNGQTAVAKQNGASVSVAVKADAGLPENVVHLPLHTENAA
                     LGALMDTIELAGA"
     gene            27633..28709
                     /gene="nuoH"
                     /locus_tag="ACFOAE_000077"
     CDS             27633..28709
                     /gene="nuoH"
                     /locus_tag="ACFOAE_000077"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HFC6883657.1"
                     /translation="MQEWFQNLFAATLGLGDLGITVGLVVSVIVKIVIILIPLILTVA
                     YLTYFERKVIGFMQLRVGPNVTGPWGLIQPFADVFKLLFKEVTRPKLSNKALFYIGPI
                     MSLAPSFAAWAVIPFNEEWVLTNINIGLLYILMITSLSVYGVIIAGWASNSKYSFLGA
                     MRASAQSISYEIAMSAALVCVVMVSGSMNFSDIVAAQAKGIAGGSVFSWNWLPLFPIF
                     IVYLISAVAETNRAPFDVAEGESEIVAGHHVEYSGFAFALFFLAEYIFMILIAALTSL
                     MFLGGWLSPFPQSWGFIGTPSAFWMFVKMAAVLYWYLWIRATFPRYRYDQIMRLGWKV
                     LIPIGFAYIVILGVWMISPLNLWK"
     gene            28790..29269
                     /gene="nuoI"
                     /locus_tag="ACFOAE_000078"
     CDS             28790..29269
                     /gene="nuoI"
                     /locus_tag="ACFOAE_000078"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HFC6883658.1"
                     /translation="MANLVKTFLLGELVKGMGVTLKNFFARKDTIYFPEEKTPQSVRF
                     RGLHAQRRYPNGEERCIACKLCEAVCPAMAINIESEEREDGTRRTKRYDIDLTKCIFC
                     GFCEEACPTDAIVETHIFEYHGEKKGDLHMTKPILLAIGDKYEAEIAKRKAADAPYR"
     gene            29281..29952
                     /locus_tag="ACFOAE_000079"
     CDS             29281..29952
                     /locus_tag="ACFOAE_000079"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HFC6883659.1"
                     /translation="MTFSAILFYILAAIVLYGALRTVTAKNPVHAALHLVLTFCVSAM
                     LWMLMQAEFLGVTLVVVYVGAVMVLFLFVVMMLNIDIEEMRAGFWRHAPVAGVVGTLL
                     AVALILILVNPKTDLAAFGLMKDIPADYNNIRDLGSRIYTDYLLPFELAAVLLLLGMV
                     AAIALVHRKTVNPKRMDPADQVKVRADQGRMRLVKMEAVKPQTESAEESEVSDDLKPK
                     EEGKA"
     gene            29949..30254
                     /gene="nuoK"
                     /locus_tag="ACFOAE_000080"
     CDS             29949..30254
                     /gene="nuoK"
                     /locus_tag="ACFOAE_000080"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HFC6883660.1"
                     /translation="MITLTHYLVLGALLFGISAMGIFMNRKNVLVLLMSIELMLLAVN
                     FNFIAFSQHLGDTAGQIFVFFVLTVAAAESAIGLAIMVLVYRNRQTINVADLDELKG"
     gene            30288..30863
                     /gene="fic"
                     /locus_tag="ACFOAE_000081"
     CDS             30288..30863
                     /gene="fic"
                     /locus_tag="ACFOAE_000081"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009175035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFC6883661.1"
                     /translation="MPSENPIGKTMKSIDEQSLHNARRLFESGDIDRIEVGTTAGLQQ
                     IHRYLFGGLYDFAGQIREDNISKGGFRFANAMYLKEALVKIEQMPERTFEEIIAKYVE
                     MNIAHPFLEGNGRSTRIWLDLVLKKNLKKVVNWQNVSKTLYLQAMERSPVNDLELRFL
                     LKDNLTDDVDNREIIFKGIEQSYYYEGYEKG"
     gene            30987..31328
                     /locus_tag="ACFOAE_000082"
     CDS             30987..31328
                     /locus_tag="ACFOAE_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883662.1"
                     /translation="MMDKNQLEQEFHKAMLNIYQEALNLPQPYKATRFLQIVNEFGGK
                     EAADKLLSTGEKKTQTGFTELILSGGGVHALKYSMEYLVLQKPWCDLFTEEQLAVARK
                     RLERVGFVSPK"
     gene            31377..33401
                     /gene="nuoL"
                     /locus_tag="ACFOAE_000083"
     CDS             31377..33401
                     /gene="nuoL"
                     /locus_tag="ACFOAE_000083"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HFC6883663.1"
                     /translation="MNDMTLYLIIALVPLAGSLIAGLFGNKIGRAGAHTVTILGVAVS
                     AVLSAYVLWGFIDGSRAKFDENVYTWLTMGGLDFSVGFLVDTMTAMMMVVVTGVSLMV
                     HIYTIGYMHDEKIGYQRFFSYISLFTFSMLMLIMSNNFIQLFFGWEAVGLVSYLLIGF
                     YFKRPSATFANLKAFLINRVGDFGFLLGIGLVLAYFGGSLRYQDVFAYLPNVQNATIQ
                     LFPGVEWSLITVTCLILFVGAMGKSAQFPLHVWLPDSMEGPTPISALIHAATMVTAGL
                     FMVSRMSPIYEMSSTALSVIMVIGAITALFMGFLGVIQNDIKRVVAYSTLSQLGYMTV
                     ALGASAYSVAMFHVMTHAFFKALLFLAAGSAIIGMHHDQDMRHMGNLKKYMPITWLTM
                     LIGNLSLIGTPFFSGFYSKDSIIEAAKYSTLPGSGFAYFAVLASVFVTAFYAFRQYFM
                     VFHGEEKWRSLPEHHDDHHGEEHHSLGKNDNPHESPLVVTLPLILLAIPSVIIGYLAI
                     EPMLYGDFFKDVIFVNTDAHPTMHIMKEEFHGALAMVSHSLHSPVLYLAIAGVLSAWL
                     LYVKLPHLPAKIAQTFRPVYVLFENKYYLDALYFNVFAKGTRALGTFFWKVGDTAIID
                     NGIVNGSAKLVGAIAAQVRKAQTGFIYTYAAAMVFGVLVLLGMTFWGLFR"
     gene            33585..34748
                     /locus_tag="ACFOAE_000084"
     CDS             33585..34748
                     /locus_tag="ACFOAE_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HFC6883664.1"
                     /translation="MTQLFLHSDTPNEKELISIYEKAVSEAVELYIFSAYLTHWDVKN
                     KLNSKLQEFKFIFGQDFGLSKKEAIRKVLKWLPSHLKFTLMVAQGIQGFHPKAVFWKN
                     DKNEYYALIGSSNLTHAAFNSNYEANILTKISEQDFIKVKSWADEIAMKSIPVSEDWL
                     EEYQEAEINYKKSTVSQSLMDKLFMEMPNYNQELIAARRKQMRNHQTVCNQLKSLIKQ
                     CAAGKIDNDEFYVEFNKLWSWKSENKGEGVGNRFQDQTWKRTGKSSDFRKLCIAIQSV
                     FDAPLAERDNVVAKQIDWLKECGVSTRGSVFSEMLCQEYPDRYPVLNAPIKKFLEKNK
                     FKSAKGASEGSRYIDLSMKLRALLAMQSEIKNLAELDVLVQAEYRDSTDIDWE"
     gene            34858..36354
                     /locus_tag="ACFOAE_000085"
     CDS             34858..36354
                     /locus_tag="ACFOAE_000085"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HFC6883665.1"
                     /translation="MFSNYLLSLAIWIPIAAGVLVLSTGKDSRAPLARVLAFMGALAG
                     FLVTLPLFTGFDRLSGGYQFTEFHEWIPLLKINYALGVDGISVLFIILNAFITLLVVL
                     AGWEVIQKRPAQYMAAFLMMSGLINGAFAAQDAILFYVFFEGMLIPLYLIIGVWGGPR
                     RVYASVKLFLYTLMGSLLMLVAMVYLYYQTGSFSIVDFQNIKQIPLGVQQLLFAAFFL
                     SFAVKVPMFPVHTWLPDAHVEAPTGGSMVLAAITLKLGAYGFLRFILPIMPDAARYFA
                     PVIIVLSLIAVIYIGMVALVQTDMKKLVAYSSISHMGFVTLGMFLFVDGQLDDWALKG
                     AVIQMISHGFVSAAMFMCIGVMYDRLHTRNIADYGGVVNVMPKFAAFMMLFGMANAGL
                     PATSGFVGEFMVIMGAVKVNFWVGALAAMTLIYGASYTLWMYKRVIYGAIHNPHVAEM
                     KDINCREFAILAILAVVVLGMGLYPQAFIEVVHQAANDLIAHVAQSKI"
     gene            36364..37809
                     /gene="nuoN"
                     /locus_tag="ACFOAE_000086"
     CDS             36364..37809
                     /gene="nuoN"
                     /locus_tag="ACFOAE_000086"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA];
                     GO_process: GO:0042773 - ATP synthesis coupled electron
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HFC6883666.1"
                     /translation="MNWSDLNLMPAMPEVALLSLLVLLLLADLWVSDDKRRWTHYGAL
                     ATVAVTAVVQLAVWEQGSTSSFNGMYIADGMSRLAKMVLYALTFALFVYAKPYNQVRG
                     IFKGEFYTLSLFALLGMSVMVSAGHFLTAYIGLELLSLALYALIALRRDSGFAAEAAL
                     KYFVLGALASGLLLYGISMVYGATGSLEFAGVLASSFNEEANEWLLKLGLVFIVVAVA
                     FKLGAVPFHMWVPDVYHGAPTSVTALVGTAPKIAAVVFAFRILVTGLGTVHHDWSLMF
                     ALLAAASLLVGNLAAIMQTNIKRMLAYSTVSHMGFILLAFMAGAVGFAAGLYYAITYA
                     LMAAAGFGVLMVLSDGDDECENISDLAGLNQHRVWLAFLMLLVMFSMAGIPPLMGFYA
                     KFGVIMALLKQGYVWLSVFAVVMSLIGAFYYLRVVKVMYFDESGRARPTVGGNNAAKF
                     LLSVNALLLVLWGIMPQTVIDWCAKALENTL"
     gene            37921..38220
                     /locus_tag="ACFOAE_000087"
     CDS             37921..38220
                     /locus_tag="ACFOAE_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2818 family protein"
                     /protein_id="HFC6883667.1"
                     /translation="MTASMYILLLLALIFANAPFLTTRLFGIVPLKRKHFGHHLIELA
                     AGFALTAVLAYILESRAGAVHDQGWEFYATVVCLYLIFAFPCFVWRYFWHTRNRE"
     gene            complement(38329..39225)
                     /locus_tag="ACFOAE_000088"
     CDS             complement(38329..39225)
                     /locus_tag="ACFOAE_000088"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFC6883668.1"
                     /translation="MNPTNDLKAWQQRAQAQTELLLERFLPSENEIPHTLHEAMRYAV
                     LDGGKRLRPMLVLAASELGEAVHEAVEQAMAAIEMIHAYSLVHDDMPAMDNDSLRRGK
                     PTCHIKYGEATALLVGDALQTQAFDVLSRPTELPAARQLAMLSVLAKAGGSAGMAGGQ
                     AIDLANVGKQMVQADLEQMHSLKTGALIRAAVLLGAMSCPNLSEDSLAVLDDYAAKLG
                     LAFQVIDDVLDCEADTATLGKTAGKDADNDKPTYVKLMGLEAARSYAHKLVAEAVALL
                     EPFGDKALRLRQLAEFAVARKY"
     gene            complement(39209..39517)
                     /locus_tag="ACFOAE_000089"
     CDS             complement(39209..39517)
                     /locus_tag="ACFOAE_000089"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFC6883669.1"
                     /translation="MPSEILLFQTASGFQKCYNSVFTETPETMKKNAPKSFEEALSRL
                     ESLTQSMQGEMPLEDALAAYQEGNELVRYCQTKLAQVEQKLQVLDADGPKELNLESDE
                     "
     gene            complement(39545..40468)
                     /gene="rsgA"
                     /locus_tag="ACFOAE_000090"
     CDS             complement(39545..40468)
                     /gene="rsgA"
                     /locus_tag="ACFOAE_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFC6883670.1"
                     /translation="MPSEHPFSDGISTPNPKETMNDTAQITASYGRRYIVRTPDGTTY
                     EASTRKKRVDFACGDRVRISPVNAEQVVIEDFLPRQSLLYRQDAWKTKLIAANVTQLL
                     IVTAAVPSPSVRLLQRALLAAEAAGIRAVIVLNKADLPETALWREKLKFYETLGYPVI
                     ETRALENAGSLRPALQGHSNILLGQSGMGKSTLTNALLGSQTARTGDISAALDSGKHT
                     TTHARLYDLNGETQLIDSPGLQEFGLHHLQAADLPRYFPDFRHLVGQCRFHNCTHRAE
                     PGCAFKAAAQTGKIRTERLTFLQRITDDLLK"
     gene            complement(40473..42329)
                     /locus_tag="ACFOAE_000091"
     CDS             complement(40473..42329)
                     /locus_tag="ACFOAE_000091"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC6883671.1"
                     /translation="MLNKIFSWFESRIDPYPEAAPKTPEKGLWRFVWSSMTGVRKWIA
                     ALAALTAGIGIMEALVFQFMGKIVEWLGKYAPTELFAEKGWELAAMAAMMVFSVAWAF
                     AASNVRLQTLQGVFPMRLRWNFHRLMLNQSLGFYQDEFAGRVSAKVMQTALALRDAVM
                     TVADMVVYVSVYFITSGVILASLDSWLLLPFIGWIVGFASVMRLLIPKLGQTAAWQAD
                     ARSLMTGRITDAYSNIATVKLFSHGAREAAYAKQSMEEFMVTVRAQMRLATLLHSCSF
                     IVNTSLTLSTAALGIWLWHNGQVGVGAVATATAMALRVNGLSQYIMWESARLFENIGT
                     VGDGMATLSKPHTILDKPNALPLKVSQGEIKFEHVDFSYEAGKPLLNGFNLTIRPGEK
                     VGLIGRSGAGKSTIVNLLLRFYEPQSGTVLIDGQDISGVTQESLRAQIGLVTQDTSLL
                     HRSVRDNIIYGRPDATDAEMVSAAERAEAAGFIPDLSDAKGRRGYDAHVGERGVKLSG
                     GQRQRIAIARVMLKDAPILLLDEATSALDSEVEAAIQESLDKMMDGKTVIAIAHRLST
                     IAAMDRLVVLDKGRIIEEGTHAELLEKRGLYAKLWAHQSGGFLNEHVEWQHD"
     gene            complement(42355..42492)
                     /locus_tag="ACFOAE_000092"
     CDS             complement(42355..42492)
                     /locus_tag="ACFOAE_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883672.1"
                     /translation="MPSEGGAAFALTKPCVSAPRCLPDGFSRKMALLSFLSDGIVFDA
                     V"
     gene            complement(42492..43076)
                     /gene="ruvA"
                     /locus_tag="ACFOAE_000093"
     CDS             complement(42492..43076)
                     /gene="ruvA"
                     /locus_tag="ACFOAE_000093"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFC6883673.1"
                     /translation="MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGES
                     VQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVGGIGAKTALGILSAMTADELARAV
                     AEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHTVTDGLFAAAPAADETEDIVSTLLA
                     LGYSEREAKAAVKGVPEGTDVGEGVRLALKNLLK"
     gene            complement(43158..43484)
                     /locus_tag="ACFOAE_000094"
     CDS             complement(43158..43484)
                     /locus_tag="ACFOAE_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFC6883674.1"
                     /translation="MNIKHLLLTAAATALMGISAPALAHHDGHGDDDHGHAAHQHSKQ
                     DKIISRAQAEKAALARVGGKITDIDLEHDNGRPHYDVEIVKNGQEYKVVVDARTGRVI
                     SSRRDD"
     gene            complement(43546..44265)
                     /locus_tag="ACFOAE_000095"
     CDS             complement(43546..44265)
                     /locus_tag="ACFOAE_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="HFC6883675.1"
                     /translation="MTLTRKTLFLLTAAFGTHSLQTASADAVVKAEKLHASANRSYKV
                     AGKRYTPKNQVAEFTQTGNASWYGGRFHGRKTSGGERYDMNAFTAAHKTLPIPSYVRV
                     TNTKNGKSVIVRVNDRGPFHGNRIIDVSKAAAQKLGFVSQGTAHVKIEQIVPGQSALV
                     AENKDIFIDLKSFGTEHEAQAYLNQAAQNLASSASNPNLSVEKRHYEYVVKMGPFSSQ
                     ERAAEAEAQARGMVRAVLTAG"
     gene            complement(44262..44384)
                     /locus_tag="ACFOAE_000096"
     CDS             complement(44262..44384)
                     /locus_tag="ACFOAE_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFC6883676.1"
                     /translation="MPSENLSGHIPNRRPHCTAVRNVSGGHDAHSSSTQERNTF"
     gene            complement(44395..44859)
                     /gene="trmL"
                     /locus_tag="ACFOAE_000097"
     CDS             complement(44395..44859)
                     /gene="trmL"
                     /locus_tag="ACFOAE_000097"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFC6883677.1"
                     /translation="MFTIVLYQPEIPPNTGNIIRLCANTGADLHLVKPLGFPLDSAKM
                     KRAGLDYHEFASLTVHENFDDCLKALAGRRIFALTTKGTARPDETAFQKGDVLLFGPE
                     TRGLPADILDSLPAAQKIRLPMQPGSRSMNLSNTVAVILFEAWRQHGYAGGV"
     gene            complement(44924..45649)
                     /locus_tag="ACFOAE_000098"
     CDS             complement(44924..45649)
                     /locus_tag="ACFOAE_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFC6883678.1"
                     /translation="MDFLSRWRRIADAPTIRRCVLCHGSSGVSDGICAGCAADLAAYR
                     TDAANSCPLCFRHIQGGAVCGGCQKKPPAFDRMWASLHYEPPVSNMIHALKHLADLSM
                     VQPLADLMMQNPPDRLADECFDFVLPVPLSRERLLQRGFNQSESIVGLLAQRYGWQIL
                     PRHTVFRHHRPPQSTLKGGERRRNIKNAFEIRTPIPENCNILLIDDVFTTGATLDELA
                     KTLKKSGANRICCWTLARTPMKK"
     gene            45648..46391
                     /gene="bioH"
                     /locus_tag="ACFOAE_000099"
     CDS             45648..46391
                     /gene="bioH"
                     /locus_tag="ACFOAE_000099"
                     /EC_number="3.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HFC6883679.1"
                     /translation="MPDAVKKVYLIHGWGANRHMFDDLMPRLPATWPVSAVDLPGHGD
                     APFAQPFDIEAAADAVAAQIDTPADILGWSLGGLVALYLAARHPDKVRSLCLTASFAR
                     LTAAEDYPEGLAAPALGKMVGAFRSDYAKHIKQFLQLQLLHTPDADGIIGRILPDLAR
                     CGTPSALQEALDAAERADARHLLDKIDVPVLLVFGGKDAITPPRMGEYLHRHLKGSRL
                     VVMEKAAHAPFLSHAEAFAALYRDFVEGV"
     gene            46393..47181
                     /locus_tag="ACFOAE_000100"
     CDS             46393..47181
                     /locus_tag="ACFOAE_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFC6883680.1"
                     /translation="MNPQDKCWQVHRHLAEYADQRLTLVRNAPKYILLAGADADISRS
                     LLAKRYPQAVFEEYDSRADFLAAAAAARKGGFWQRFTGKGVVQHCQSPIAPLPEACAD
                     MLWSNLGLLAAEQILPVLHNWACALKTDGLLFFTCFGRDTFTELKCRLKENGIESRSV
                     MFPDMHDLGDMLAENGFYDPVTDTAKLVLDYKKAETFWADMDTLGIWRAMAWNDENAA
                     RSCVGTIFEREGGLSITLETVYGHAVKKLMLPQGENVVQFFPKR"
BASE COUNT        10964 a        12042 c        12657 g        11609 t
ORIGIN      
        1 ctataaaaat gccgtctgaa acggtttcag acggcatttc gatgtcggcg gcggctttgc
       61 ggaatcagcc tttgaagcgt ttgaagacca gcgtgccgtt ggtgccgccg aagccgaagg
      121 agttggaaat ggcaacgtcg atttccgcgt cgcgcgcttc gttggcgcag tagtccaaat
      181 cgcagccggc ttcaacgtct tgttcaaaaa tgttgatggt cggcgggatt ttgccgtcgt
      241 gtatcgccaa aatgctgtac acggcctcca cgccgcccgc cgcgccgagc aggtggccgg
      301 tcatggattt ggtcgagctg acgacggttt tgtaggcgtg ttcgccgaac gcgcgtttga
      361 gggctttggt ttcgttggca tcgcccaagg gggtggacgt gccgtgcgcg ttgacgtaat
      421 ccacgtcttc gggattgatg ccggcatctt tcagcgcgcg ggtaacggca agggcggggc
      481 cttcttcgtt cggcgcggtg atatggtaag catcggaact catgccgaag ccgacgattt
      541 cggcgtagat tttcgcgccg cgttttttgg cgtgttccaa ttcttccaac accaatatgc
      601 ccgcgccttc gccgataacg aagccgtcgc ggcctttgtc ccacggacgg gaagcggtgg
      661 cggggtcgtc gttgcgggtg gagagggctt tcatcgcggc aaaaccgccc acgcccaaag
      721 tgctgattgc gccttccgcg ccgccggcaa ccattatgtc cgcgtcgccg tatttgatca
      781 gtcgggcgga attgccgatg gcgtgcgcgc cggtggtaca ggcggaaacc atcccgtagc
      841 tcgggccgcg gtagcctttg aggatggtaa cgtgtccgga aatcaggttg atcagcgaac
      901 cggggataaa gaaagggttg attttgcgcg cgccgccttc gattacggct ttgccggtga
      961 cctcgatgct gggcagtccg ccgatgccgg aaccgatgtt cacgccgatg cggtctttgt
     1021 cgaggttttc cacatcgtcc aagcccgaat cggcgattgc ctgcaatgcg gcggcaatgc
     1081 cgtagtggat gaatacgtcc atccggcgcg cttctttcgc gctgatgtat tgtccgatgt
     1141 cgaaaccgcg cacttcgccg gcgacacggc tgttgatgtc ggatgcgtca aagcgggtaa
     1201 tcgcgccgat gccgcttttg ccggcgagca gggtgtccca agcctctgcg acagtgttgc
     1261 cgacagggga aacctgacct aagcctgtaa tgactactct tctctgactc atgataacct
     1321 cgctgttggt tgtcggaatg ggggcatatg cggctgtcgt gcagatgccg tctgtaattt
     1381 gcggcagggg ttcaaacagt ttgccatata agggaaaagc ctctattgcg cggtgcagca
     1441 gaggctgttg tgtcgggcga cgaccggtta gccgttgtgg gcattgatgt agtcgatagc
     1501 cagttggacg gtggtgattt tttcggcatc ttcgtcgggg atttcgcagc cgaatgcttc
     1561 ttccaaagcc ataaccagct ccacggtgtc caaagaatcc gcgcccaagt cgtcttggaa
     1621 agaagattcg tttttcacgt cggcttcgtt tacgcccagt tgttcagcaa caattttttt
     1681 aacttgttgt tcgatgtttg acatatcagt cgttccttta tgccttgcgg caggttgttt
     1741 aagggaaata aatcggtggt attgtaccga cttttaatag agttttctat ctaatgacta
     1801 ttatatcaat atttgccgat ttgtacattt ttgggtgcgg cgggttttgt cgttcaagtt
     1861 tgacctgtgt gccgtatgtt tggcgggatt tcggttaaaa tggcggcatt tccatctgaa
     1921 gcagaaagcc ctgtcatgta tccacttgcc cgccgcatcc tgtttgcact cgatgccgaa
     1981 aaagcccacc acttcacgct cgacgcgctc tacacggttt ataaattggg tctgattccc
     2041 gtaaccggca accgtaccaa acctgtaaaa ttgatgggta tggatttgcc caaccctgtc
     2101 ggacttgccg ctggactcga caaaaacggc gaatacatcg acgcattggg cgcgctcggc
     2161 tttggtttca tcgaaatcgg cacggtaacg cccaaaccgc agcccggcaa cccgcagccg
     2221 cgcctctttc gcgttcccga acaccaaggc atcatcaacc gcatgggttt caacaaccac
     2281 ggtatcgaca ccatgatacg caacatcgaa aaaagtaaat tcagtggcgt attgggcatc
     2341 aacatcggta aaaacgcggt tacacccatc gaaaacgctg ccgatgatta tttaatctgc
     2401 cttgaaaaag cctacgcaca cgcaagttac attaccgtca acatttcctc gcccaacacc
     2461 aaaaacctcc gcgcgctgca aggtggcgac gagttgagcg cattgcttga ggctttgaaa
     2521 aacaaacagg cacagcttgc ctctgtatac gggaaatacg ttccgctcgc cgtcaaaatc
     2581 gcccccgatt tggatgaagc acaaatcgaa gacatcgccc acgttgtcaa atccgtcgaa
     2641 atggacggca tcatcgctac caataccacc atcgacaaat caagtctcgg cagccatccg
     2701 ctcgcaggcg agcagggcgg tttgagcggg ctgcccgttc atgaaaaaag taatcgggtg
     2761 ttgaagctgt tggcagacca catcgacggc aagctgccga ttatcggcgt aggcggcatt
     2821 atggaaggcg gggactcggc agataaaatc cgcttgggcg cgaccgccgt ccaagtgtac
     2881 agcggattga tatacaaagg tccggcattg gtcaaagaat gtttgaaggc tttggcgcga
     2941 tgacgcgtcc cgcccaaaat gccgtctaaa cgcacgtttt gccgttcaga cggcattttc
     3001 atttcctttt tccgcctgcc gccccttgaa aatcccttac gcgccgccct gtttgaaaca
     3061 aagcaaacgc ccgccgcgaa ccggacaatc ttgatacgca gccaaagcaa gtccggcggt
     3121 aagttgttaa atatataagc aattgataca aaaaataatt ttatactgtg gcggacggct
     3181 tgggaaaacg caaaatatga acggcgttga aattcatgat gtggaaaata aggatacggc
     3241 ggataatcaa aagattttat atttaaggat ttgatatgtt taaggacgaa ctaaatgaat
     3301 ttatccgatt gatatccgat ccggaaagtg aattggatga atggtatttg agtgatttta
     3361 aagatgaaca tatatgggaa atgcaaagtt acgaagcatt ttcatgtttg cgggaagcag
     3421 tcccctattt gtttgcttat ccccgatacg ggtatgaact gttggagata atttccgcgt
     3481 taaaagaaac atctgatacg acagaattat tttatgagcc gggtatcgtg cctttgctga
     3541 ttgatttata taaagaagat agttatctgg taaatatggt caaacggata ttcaaatgat
     3601 gaaaggggcg cgggcgtttg cttggcggaa ggcaggtaac tcaatttgaa ggacgcggaa
     3661 gccgatacgt taaaaaggat gaaaaatgga aaacgggcaa cggaataacc ggttttcttt
     3721 ggaaaaacga attttttatc tggagcattc ggggcggtat ctgatgattt gcgccttatc
     3781 ggattattcc caaaacaaac atactgtcgt tatggcaaat ttcatctatc cggatgaaaa
     3841 aacggattgg cggaatttgg atgatttatt caatgagttg gttttagagg aattgcaggc
     3901 ttcatttatg gattggcatc cgactgttga agaggcaatc agccgtcatt tggaagactt
     3961 ttcgtaacag gcgtcaatcg gaaggggcgg aatgacgggg caggcaatcg gagtaaaaaa
     4021 tgaaccttga tttaaccgcg caaaaagtcc gtctttcttg gaaggatatt ctgtgggggt
     4081 atgggaataa atacttgggt tgggctgatg tggcagctta tgcccgaaaa atgacgcttt
     4141 cagatcatga tgaacgtgtg ttcaaactat ctttaatcaa caaatccaat attcttgaat
     4201 taaagcctgt tctggaagat ttggcttcgg aaatgaggga ttattcccct aaaaattggc
     4261 tgtacgtcct cttaagcgat gtattccata gaaaagaaga atttgaggat cctttggggg
     4321 aagttgaaaa aatttatgca gattttgatt atccggaaga aatagaatca tttgtcaggt
     4381 atatgccgcc caaagacggt tatattcctt ctgcccacac ctatgaagaa aatattgccc
     4441 ggttatattc tcactgggaa cactatttga acaacggcgg agggcagggt taaaaccggc
     4501 aatccgatgc cgtctgaagc attatccggc cttcagacgg cattttgttt tccgacagtt
     4561 tataaactgt cgttgtttct tgacagaaac aacgacctta tttatttgaa acgattggag
     4621 gacatgatta tgggtttttg gaatggtgtg gcaaaagcag tgggagaggg aatgattgaa
     4681 gccggcaatg agcataaggc gttgaaaatg gaatatgcgg agaaatcaag tgaggagctg
     4741 catgaaatcg tcaagagtga tggtttttta aaaattccac acgggagaaa agtgcggctt
     4801 atgctgtttt aaaagagcgt ggcgaggtgt gaacaggaaa cggcggcatt tgccgctgtt
     4861 ttttattggt aggagtccgt ctggatgtcg gggcaaggtt tcagacggca tcgaaggttg
     4921 ctatgatata gtggcttgac tttaaaccgg tacggcatcc cctcgccctg tcctgatttg
     4981 aagtgaatcc gccatcatct tcctgccatt ttttcaaacg gaatccgaaa tgtccgacaa
     5041 ccgcctcgac accgcccgcc gccattccct cttcctcgcc cgccagctcg acaacggcaa
     5101 actcaagccc gaaattttcc tgcctatgct ggacaaggtt tggaccgaag cggatttcca
     5161 agcctttgcc gactgggaca aaatccgtgc ggaagaaaac gaggaagaat tggcgcggca
     5221 gttgcgcggg ttgcgccgtt atgtggtgtc gcagattatc gtgcgcgata tcaaccgtat
     5281 cagcgatttg aacgaagtaa cccgcacgat tacgctgttt gccgattttg ccgtcaatac
     5341 cgcgctggat tttgcctacg cctattatcg ggacatgtac ggcacgccga tcgggcgtta
     5401 taccaaatcg ccgcagcatt tgagcgtggt ggcgatgggc aaggcgggcg gctatgagtt
     5461 gaacgtgtct tccgacatcg atttgatttt catctatccc gaatctggcg acaccgacgg
     5521 caggcgcgaa cggggcaatc aggagttttt caccaaagtc gggcagaaac tgattgcgct
     5581 gctgaacgac atcaccgccg acgggcaggt gttccgcgtc gatatgcggc tgcggccgga
     5641 cggtgattcg ggcgcgttgg tgttgagcga aaccgcgctg gagcaatacc tgattacgca
     5701 ggggcgcgaa tgggaacgct acgcgtggtg caaaggccgt gtggttacgc cgtatccgaa
     5761 cggaatcaaa tcgctggtgc gccccttcgt gttccgcaaa tatctggatt acggcgcgta
     5821 tgaggcgatg cgtaagctgc accgccaaat ctgcagcgaa gtcagcaaaa aagggatggc
     5881 ggacaacatc aaactcggcg cgggcggcat ccgcgaagtc gaatttatcg cccagatttt
     5941 ccagatgata cgcggcggcc aaatgcgtgc gctgcaactg aaaggcacgc aggaaacgct
     6001 gaagaaactt gccgaaaccg ggatcatgcc gtctgaaaac gtcgaaaccc tgcttgccgc
     6061 ctaccgattc ctgcgcgatg tcgaacaccg cctgcaatac tgggatgacc agcaaaccca
     6121 aaccctgccg gcttcgcccg aacagcagca actgcttgcc gaaagtatgg gtttcgacag
     6181 ctacgccgct ttttcagacg acctcaatgc ccaccgcacc aaagtcaatc agttgttcaa
     6241 cgaaattttg agcgaaccgg aagagcaaac gcaaagcaac ggcgaatggc agtgggtttg
     6301 gcaggaaaaa cccgacgaag aagggcggca atgccgtctg aaagaacacg ggttcgatgc
     6361 cgaaaccatc gccacgcggc tcgaccaaat ccgccacggc cataaatacc gccatctttc
     6421 cgcacacgcc cagccgcgtt tcgatgcggt tgtgccgctg ttcgtacagg cggcggcagc
     6481 gcaaagcaac ccgaccgata cgctgatgcg gctgtttgac ttcctcgaaa acatcagccg
     6541 ccgctccgcc tatctcgctt tcctcaacga acatccgcaa accttggcgc aactggcaga
     6601 gattatgagc caaagctcgt gggtggcggc gtatctgaac aaatatccga ttttgttgga
     6661 cgaactcatc agcgcgcagc ttttggatac cgcgtttgat tggcaggcac tcgccgctac
     6721 cctttcagac ggcatcgaag cctgcggcgg cgataccgaa gcgcaaatgg acaccctgcg
     6781 ccgctttcag cacgcccaag tcttccgcct cgccgtccaa gacctcgccg gactgtggac
     6841 ggtagaatcc ctctccgacc aactttccgc cctcgccgac accatcctcg ccgccgccct
     6901 gctgtgcgcg tgggcggaca tgcccaaaaa acaccgcgac accccgcaat tcgccgtcgt
     6961 cggctacggc aaactcggcg gcaaagaact cggctacgcc tccgacctcg acctcgtcta
     7021 tctctacgac gatccccacc ccgacgcagg cgacgtgtac agccgcctcg cccgtcgcct
     7081 gaccaactgg ctttccgccg ccaccggcgc aggcagcctc tacgaaaccg acctgcgcct
     7141 gcgccctaat ggcgacgccg gtttcctcgc ccacagcatc gccgcctttg aaaaatacca
     7201 gcgcgaaaac gcctggacgt gggaacacca atcccttacc cgcgcccgct tcatctgcgg
     7261 cacgcccgaa attcagacgg ccttcgaccg catccgcacc gaaatcctca ccgccgaacg
     7321 cgaccaaacc gccttgtcag gcgaaatcat cgaaatgcgc gaaaaaatgt tccccaccca
     7381 tccgcctgcc gacagcaacg tcaaatacgc acgcggcggc gtagtagacg tcgaatttat
     7441 cgtccaatat ctgatacttg cccacgcccg aaaatatccg caactcctcg acaactacgg
     7501 caacatcgcc ctcttgaaca tcgccgccga ctgcggtttg attgataaaa cgcttgccgg
     7561 acaaagccgc accgcctacc gcttctaccg ccggcagcag cacaacacca aactgcgcga
     7621 cgcggcaaaa accgaagtaa ccggcgaact gttggcacat tacggcaatg tcaggaaatt
     7681 gtggcgggaa gtgttcggcg aagaagcggc aaccgcctga acaaaaaatg ccgtctgaag
     7741 cctgacaatc tgggtttcag acggtatttt cgtaccgtgc cgttttaagg ttgcggcaga
     7801 gctaaagcga tttatcggga atggctgaaa cccaaaaacc ggattcctct ttcagttaca
     7861 gcagcttgat ccctttccct tatccaacgg gggaaggcta ggatagggtg gcttgcaaat
     7921 atacagaaca agggacaaga gccaccctct ctccaaccct ctccctccgt acgggagggg
     7981 gtggattctc gcgggcgaag cccacgctac ggttagcctt caccccagca caaacaattc
     8041 ccgcccgtgc gccttcagcc aacttttagc attgtcggta tgcggcgtca gcgtgttcac
     8101 caaatgccaa aagcgcggac tgtggtcggg gtggcggagg tggcagagtt cgtggatgca
     8161 gacatagtcg gcgacgtatt cgggcgtgcc gatcagccgc cagttgaggc ggatgccggt
     8221 gtgcgggcgg catacgcccc aaaaggtttt ggcgttgctc aggtctgtgg cggtgggcgt
     8281 cagtcctgtt tcggctgcgt gtttttcaag gcggggcagc aggtattcgc gggcgcgttc
     8341 gttcaacagg cggcgcaggt ggtcgatttg tgcggcggtt tcttttcggg gaagcaggat
     8401 ttcagacgac gtgatacgga tatggctttg gctgtgggta tccagcttgg tctttattcc
     8461 ccgataccaa atccactcgg gtaagtttgg gtgggaaaca ggatgcacgg gcgttttggc
     8521 aagcgtgttc cgcaaaatcg tttcgtttgc cgccagccag tttgctaacg cgtggtcttg
     8581 aaaaaagggt gggacgttga tgctgaccgt ctgcatattg acggggcgca gaatcagatt
     8641 tttcttggca ctgcgtttga gttcgatttc gatgcacaaa ccgtcggaaa gagtataggt
     8701 gaagcgtttc atagttgtga atgggtttca gaccggatac atcgtctgaa acaggaattt
     8761 tccatatcag gcggcaaact tcggataata tacaaaatca aacatctgcg ctacaaggtt
     8821 cagccgaaca agccgccgat atatttgctg atggtgatgg cgctgagtac tgccatcaaa
     8881 ccgaccacaa tcacgccgga aacggtgagc cacagcgggt gtttgtagtc gccgacaatt
     8941 ttggttttgt aggcggcaat cagaatcaga ccgagggaaa tcggtaaaat caggccgttt
     9001 aatgcgccta cgaacaccag cacctgcgcc ggtttgccga tggtggaaaa tacggcggtg
     9061 gacacggcga taaaggcaat aatccatttg tttttattgc gttcgataga cgggctgaga
     9121 ccggagaaga acgacaccga agtataagcc gcaccaatca ccgaagtaat cgaagccgcc
     9181 caaatcacca cgccgaaaat cagcaggccg atgtatcccg ccgcatattc aaacggtgtg
     9241 gaagcagggt tgtcgggatt gagctgtacg ccttggctga ccacgcccaa aaccgccaaa
     9301 aacaatacaa tccgcataat cgaggcaatc aggatcgccc gcaccgagct ttggctcact
     9361 tccggcaacg ccgatttgcc tttgatgcct gcgtccagca gacggtgcgc accggcgaag
     9421 gtgatgtagc cgccgaccgt gccgcccacc agtgtaacaa tcgccattgc atcgagtttt
     9481 tccggcataa aggtatgcac ggcggcatct gccagcggcg gattcgcctg ccatgccaca
     9541 taaaccgtca gcgcaatcat tacgaaaccc atcacttggg cgaatttgtc catcactttg
     9601 cctgcttctt taaacagaaa cacaccgatg gcaatcacgc cgctgatcac ggcaccggtt
     9661 tccggtgaca gtccggtcag caggttcaga cccaagcctg cgccgccgac gttgccaata
     9721 ttgaacgcca aaccgcccat cacaatcagc acagccaaga aatagcctgc gccgggcaag
     9781 acctgattgg caatatcctg cgcctgtttt tcggaaacgg cgacaatccg ccaaatattg
     9841 agctgcgccc cgatgtcgag cagaatcgag agcagaatca caaagccgaa acttgccgcc
     9901 agtgcttggg tgaaggtggc ggtttgggtc agaaagcccg ggccgatggc ggaagtcgcc
     9961 atcaggaatg cagcgccgat taaggcattt ctgcggtttt tttgatcaga cataatcgct
    10021 tatcctctat aaaattggtt gttgctgtgt ttgggcgaaa cctgcggttt tagctacgca
    10081 gaaactcgct ttgctcgttt tggcgaaacc tgcggttttc agacggccta tgaactgttt
    10141 ttcaagcaga aactttgatg cctgccgcca gtagttcctg ccggattttt tcggcaaaca
    10201 ccacggcgtg cggcccgtct ccgtgcagac agatgctgtc ggcttgcacg gcaaccaggc
    10261 tgccgttcac tgctttgacc cgcccgtccc gcaccatctg caatacttgg gcgatggctt
    10321 cttcgtcgct gtccacctgc gcatcggggc ggctgcgggg aaccagcgta ccgtcgggca
    10381 tatagcggcg gtcggcgaat acttcggaaa tcacacccaa gcctgcggct tttccggctt
    10441 ccaagagcag gctgccggaa agtgccatca atttcaattt cgggtcgaaa tccgccacaa
    10501 ttcgggcaac ggtatccgcc agcgcacggt ttttcgccgc ttggttgtac attgcgccgt
    10561 gcggtttgac ataagccatt tccaaaccct gatcacggca caaggcctgc aatgcgccca
    10621 actggtaatt cagacacgcc cgcaaatcgg cttcggacag attcatttcg gtacggccga
    10681 agttttcccg atcgggatag ccggggtgtg ctccgatgcg cacgccgttt tgttgggcat
    10741 acgccaatgc cgcccgaata tcggcaatgc tgccggcgtg ttgggcgcag gcgatgttgg
    10801 ccgaagtaat cagctgcaac aaggcttcgt cgctgccgca gccttcggcg agatcggcgt
    10861 ttaaatcaac ctgcttcatg ggtgattctc cgtatttggt tcagatagac ttggtttttg
    10921 cgccgcaggg cggtggcttc tttcaagccg attattttga atttgacttt gctgccgaag
    10981 cgcacctgtg ccagcctgcc caaatcggcg gcggcaacgg tagcgatttt cggataaccg
    11041 ccggtggttt gcgcatcggc cagcaggata atcggtttgc cgccgggcgg cacctgcacg
    11101 gttcctgcct gaacagcgtg ggacagcatt tccaaaggtt gcgacagggt cagcggctgt
    11161 ccgtcgaagc ggtagcccat gcggttgcta tcgctttgca gcgtccacgt ttcccgttcc
    11221 agattcagac gccctttttc actgaaagcg gcatattccg acgaaggaac aaggtggacg
    11281 gtatcggtaa acggtatcgg ggcaatgccg actttggaca attcctgcgc acctttgccg
    11341 atggggagat aatcgccttt ttgcagcatt ctgccctgat ggccgccgaa accggctttc
    11401 aggtcggtgc ttctcgaacc catcacttcc ggcacatcaa atccgcccgc cacgcacaca
    11461 tagccgtaca tgccctgcac ggcacgcacc attttcaagg tctgcccttt gcgggcggta
    11521 taacgccaat acgaatagac cggttcgccg tccaattccg cctgatacac ggcaccggtg
    11581 agacaaaacg gcgtatcccg ttcaaacacc agcattatcc cgcccaaagc gatttcgatt
    11641 gcggccgtgc cttcgtcgtt gcccaataaa atattacccg ccgccaaagc aaccgtgtcc
    11701 atcgcaccgg catgaccgat gccgtaacgc cggtgtccgt agcgtccggt atcctgaata
    11761 tgcgccggtg cctgcactgc cgaaacgtga atcatggctc aatcctttct gcaacaaagc
    11821 ggacttggtc acccgccgcc agcagggtcg gcggattcaa atcggctcgg aacaagggta
    11881 attcggttct gccgataatc tgccagccgc cgggcgaagc gaacggatac acaccggtct
    11941 gactgccgcc gataccgacc gaaccggcag gaacggacgt tctcggcacg gcacggcggg
    12001 gcgtgtgcaa tgcttcgggc aagccgccca gataagggaa accaggctgg aagcccatca
    12061 taaatacggt ataagtttgc gccgtatggc ggcggacgat ttcggaaata accgtctgat
    12121 ggaaagcagc gacttccgcc aaatccgggc cgtattcgcc gccgtagcag acgggaattt
    12181 ccaccagttt gccctgatgg tctgtaacgg cggtgtgttc ccacacatat tgcaattcat
    12241 cggcaagcgt cgccaaatcg gtatcgaaac gggtgaacac ggtcagattg ttcatgccga
    12301 ccaccacttc ctcaatcctg tcgtgctgcc cgagcgcagc ggcaaacgcc cacaactttt
    12361 gctgtttgcc cagttcggaa ggtgcattca gtcggcagac caaagcggat tcgctgattg
    12421 gtgtgatctc tattctcatt tgttgttcat tttggttatg ttttaatgaa tctatatgca
    12481 ggggcggcgg tttgtcaata tcttctgtgc tgcatcatca aaccgtcgat tggaaaagtg
    12541 ctgccctgcc gctgcacttt ttcagacgac cttaaaccgt ttctattaaa atagcgcatt
    12601 ccacttttca gacggcatct ctatgtttcc cgaccaatcc gcccccaacc tgctgcaagg
    12661 cttgaaccct gaacaacttt ccgccgtaac ctggccgccg caatccgccc ttgtgctggc
    12721 aggcgcgggc agcggcaaaa cgcgcgtgct gaccacgcgt atcgcatggc tgttgcaaac
    12781 cggtcaggca agcgtgcata gcattatggc ggtaacgttt accaataaag ccgccaaaga
    12841 aatgcagacc cgtttgggcg caatgattcc cgtcaacgtc cgcgccatgt ggctcggcac
    12901 gtttcacggt ctctgccacc gctttttgcg cctgcaccac cgcgacgcag gcctgccgtc
    12961 ttcctttcaa attctcgaca gcggcgacca gctttccctc atcaaacgcc tgctcaaaag
    13021 cctcaacatc gccgaagaaa tcatcgcacc gcgttcgctg caaggcttta tcaacgcgca
    13081 aaaagaatcc ggtttgcgcg cttccgtgtt gagcgcgccc gacccgcaca caagccgcat
    13141 gatcgaatgc tacgccgaat acgacaaaat ctgccaacgc gaaggcgtgg tcgattttgc
    13201 cgaactcatg ctccgcagct acgaaatgct gcaaagcaac gaaatcctgc gccagcatta
    13261 ccaaaaccgc ttcaaccaca ttctcgtcga cgagttccaa gacaccaaca aactgcaata
    13321 cgcctggctc aaactcatgg cgggcggaaa cgcagcggta tttgccgtcg gcgacgacga
    13381 ccaaagcatt taccgtttcc gtggcgcaaa cgttggcaat atgaccgcgc tgatggaaga
    13441 attccacatc gacgcgcccg tcaaactcga acaaaactac cgctccgtcg gcaacatcct
    13501 tgccgccgcc aacgctgtta tcgaaaacaa cgacgaacgc ctcggcaaaa acctgcgcac
    13561 cgacgccgaa gcaggcgaca aaattcgcta ctactccgcc tttaccgacc tcgaagaagc
    13621 ccggttcatc gtggacgaaa ccaaagccct cgaacgcgaa ggctgggatt tggacgaaat
    13681 cgccgtcctc taccgcagca acgcccaatc gcgcgtcatc gaacaaagcc tgttccgcag
    13741 cggcatcccc tacaaaatct acggcggctt gcgcttttac gaacgccaag aaatcaaaca
    13801 cgcgctcgcc tacctacgcc tcgccgtcaa tcccgacgac gacaacgccc tcttgcgtgt
    13861 catcaacttc ccaccgcgcg gcatcggcgc acgcaccgtc gagaaccttc agacggcctc
    13921 aaacgaacaa ggcatcaccc tctggcaagc cgcctgcaac gccggcgcga aagccgccaa
    13981 aatcgccgcc ttcgtccgcc tgattgaagc actgcgcaac caagtcggac aactgcccct
    14041 gtccgaaatc atcgtcggca tcctcaaaga cagcggcctg accgaacact accgaaccca
    14101 aaaaggcgac aaccaagacc gcctcgacaa ccttgacgaa ctcgtcaacg ccgccatcga
    14161 gttcaaaccc gaagacagca actttgaaac cctgcccgaa aacatttcag acgaccccgc
    14221 cttccccatc ctcgccttcc tcagcaacgc cgccctcgaa tccggcgaaa accaagcagg
    14281 cgcaggtgaa aaagccgtcc aactcatgac cgtccacgcc gccaaaggct tggaattcaa
    14341 cgccgtcttc ctcaccggca tggaagaagg ccgcttcccc agcgaaatga gccttgccga
    14401 acgcggcggc ctcgaagaag aacgccgcct catgtacgtc gccatcaccc gcgcccgcaa
    14461 acgcctctac atcaccatgg cacagcaacg catgctgcac ggacaaaccc aattcggcat
    14521 cgtctcccgc ttcgtcgaag aaatcccacc cgaagtattg cactacctgt ccgtcaaaaa
    14581 gcctgcctac gacagttacg gcaacacgcg tcaaactgcc acgttcaaag acaaaatcat
    14641 cgacgactac aaacagccgc aaacctacgc aggcttccgt atcggacaaa acgtccgcca
    14701 cgccaaattc ggcaccggcg tgattatcga tgccgcagat aaaggcgaat ccgcccgact
    14761 gaccatcaac ttcggcaaac agggcgtgaa agagttggat accaagtttg cgaaattgga
    14821 agcgatgtaa atttgaaatg caggctggat actcgtatcc gacaaaaata tttgacgcgt
    14881 ctatcgtttc cgaaaaaccg ctgttggaaa atgtcggatt cgagaatccg acctatggca
    14941 aaaaactgta gcaaggacaa ggcaaaaggc cgtctgaatc cggtaacaac aaattttgcc
    15001 gaaacctccg ccgtcattcc cgcgcaggcg ggaatccaga cctttcggca cgggaactta
    15061 tcggataaaa ggtttcttta gattccacgt tctagattcc cgcctgcgcg ggaatgacgg
    15121 acggtaaaag ccgggtatag atacctaacc cttgtttata gctgaaaatc aataaggaag
    15181 aacattatgt cccaagtttt taaagatttt gatttgtcct ccgtatggga atccgacagt
    15241 tgggcagatg aaaactacaa agaagccccg tttacccctg aaattttggc tgccgtagaa
    15301 agtgaactgg gctataaatt gccgcaaagt tttattgaat tgatggcggt acaaaacggc
    15361 ggaatatttg tcaaaaactg ttttccgacc acacagagaa attcgtgggc gaaagatcat
    15421 gtgcaaattt gcgaggtatc gggcatcggc tttgaaaaag aagggagttt gtgcggcgaa
    15481 acagggcaaa aactttggat ggaagaatgg gaatatccgc ccatcggcgt gtattttgcc
    15541 aacgacccgt caggcggtca tgccatgttt gccttggact atcgggagtg tggaaaagac
    15601 ggcgagccga aagtggtgtt tgtcgagcaa gaatcggatt ttgaaatcgt cgaacttgcc
    15661 cccgattttg aaacctttat ccgcagcttg cggcatgaag atgagtttat tgacgaggaa
    15721 atataaaacg gcggttgaaa aaccggaatc atcaagggaa aacgggcgaa ataacggata
    15781 atcgcttgaa tccgtaagga aaacggtttg gtggaacgcg ccatccaaga cctttgcaaa
    15841 gaaaaactgt ctccgacagc attgacatta ttaacagaac ttatcaagtt tggagctatc
    15901 tcaaatataa ttcggttatc cttttgtatc cattaaatca tatgcttcaa ttaattgttg
    15961 ttctagctct tgtaccaatt ttgaattgcg aattcctgac acaatctcaa attcttctgc
    16021 atctatgcaa acacctgcat aaatttcaat aacaagggaa cgcaataatt gaagctcttc
    16081 tcttgttaaa gaaataataa tgtcatcacc tgtgtaattg attatattca taataatttt
    16141 atttttgttt gtcaaagtaa gttttgccta aggttggtct aaatgcagtt ccaccatctt
    16201 ttgaatttgg gtctctgatt acaattgctc cagacttatc atcccaaatt gctcttatgt
    16261 gtttggattg taatcttcga attcccaaga aaaaaatcgt aataagtttg aaagtgtcaa
    16321 atcccaagtt tcttttgagc aatattctaa tattttatca atttcacttt taataatctt
    16381 atgatcaaac tgttctaata ttaatgcatt agaccaaaaa aaaccttctt tattacaatg
    16441 atgggaaatc catttaggag aacaaatgca aagtgaaaaa atagatgagc cttgttctcc
    16501 ttcgattccg atatccaaat ctatccatct atggaaatta tctggaattt cgggggtaaa
    16561 tttttcaaaa tcaatatcat ataaatttat gctttttaaa tccaatttaa tcattagggc
    16621 tgtcctagat aaatagggaa attcaaatta agttagaatt atccctatga gaaaaagtcg
    16681 tctaagccgg tataaacaaa ataaactcat tgagctattt gtcgcaggtg taactgcaag
    16741 aacagcaaca gagcctgaca gcattgttta tacggattgt tatcgtagct atgatgtatt
    16801 agatgtgagc gaatttagcc atttccgtat caatcacagc acacattttg ctgaacgaca
    16861 aaaccatatc aatggaattg agaatttttg gaaccgggca aaacgtcatt tacgcaagtt
    16921 taacggcatt cccaaagcgc attttgagct gtatttaaag gagtgcgaat ggcgttttaa
    16981 caacagtgag ataaaagttc aaatttccat tttaaaacaa ttagtaaaat cgagtttatc
    17041 ttagttgtcc aggacagccc cattattttt ataacaccgt gaagccgcac agcagtttga
    17101 acagtgatac gccgtttgcg ggcttacgag tttattttcc cggcctgcag tttgagcaat
    17161 acggtgattt cctacggtta atacaaatgt ttacacattg atacatttca tttatagttc
    17221 cgcctatttg aaaatagaaa atatgaattc gaccgcaagt aaaaccctga aaggattgtc
    17281 gctggtgttt ttcgcctctg gattctgcgc cctgatttac caggtcagct ggcagaggct
    17341 tctattcagt cacataggta tcgatttgag ttcgattact gtcattattt ctgtatttat
    17401 ggtcggcttg ggtgtaggtg cgtatttcgg tggacgcatt gctgaccgtt ttccttcaag
    17461 tatcatcccc ctgttttgca tcgctgaagt atccatcggt ctgttcggtt tggtaagcag
    17521 gggtctgatt tccggcttgg ggcatctttt agttgaggct gatttgccca tcatcgctgc
    17581 tgccaatttc ctcttattgc tgcttcctac ctttatgatg ggcgcgacct tgcccttgct
    17641 gacctgtttt tttaaccgga aaatacataa tgttggcgag tctatcggta ccttatattt
    17701 tttcaacact ttgggtgcgg cactcggatc gcttgccgcc gccgaatttt tctacgtctt
    17761 ttttaccctc tcccaaacca ttgcgctgac agcctgcttt aaccttctga ttgctgcttc
    17821 agtatggctg cgttacagaa aggatggata tagtgaacac taaaccgaat actagtttga
    17881 tttatatgct ttctttcctt agcggcttat tgagcttggg tatagaagtc ttgtgggtga
    17941 ggatgttttc gttcgcagca cagtccgtgc ctcaggcatt ttcatttacc cttgcctgtt
    18001 ttctgaccgg tatcgccgtc ggcgcgtatt ttggcaaacg gatttgccgc agccgctttg
    18061 ttgatattcc ctttatcggg cagtgcttct tgtgggcggg tattgccgac tttttgattt
    18121 tgggtgctgc gtggttgttg acgggttttt ccggcttcgt ccaccacgcc ggtatcttca
    18181 ttaccctgtc tgccgtcgtc agagggttga ttttcccgct cgtacaccat gtgggtacgg
    18241 atggcaacaa atccggacga caggtttcca atgtttattt cgccaacgtt gccggcagtg
    18301 cattgggtcc ggtccttatc ggctttgtga tacttgattt cttgtccacc caacagattt
    18361 acctgctcat ctgtttgatt tctgctgctg tccctttgtt ttgtacactg ttccaaaaaa
    18421 gtctccgact gaatgcagtg tcggtagcag tttccctaat gttcggcatc ctcatgttcc
    18481 tactgccgga ttctgtcttt caaaatattg ctgaccgtcc ggataggctg attgaaaaca
    18541 aacacggcat tgttgcggtt taccatagag atggtgataa ggttgtttat ggggcgaatg
    18601 tatacgacgg cgcatacaat accgatgtat tcaatagtgt caacggcatc gaacgtgcct
    18661 atctgctacc ctccctgaag tctggcatac gccgcatttt cgtcgttgga ttgagtacag
    18721 gttcgtgggc gcgcgtcttg tctgccattc cggaaatgca gtcgatgatc gttgcggaaa
    18781 tcaatccggc ataccgtagc cttatcgcgg acgagccgca aatcgccccg cttttgcagg
    18841 acaaacgtgt tgaaattgta ttggatgacg gtaggaaatg gctgcgtcgc catcctgatg
    18901 aaaaattcga cctgattttg atgaatacga cttggtactg gcgtgcctat tccaccaacc
    18961 tgttgagtgc ggaattttta aaacaggtgc aaagccacct taacccggat ggtattgtaa
    19021 tgtttaatac cacgcacagc ccgcatgctt ttgctaccgc cgtacacagt attccctatg
    19081 cataccgcta tgggcatatg gtagtcggct cggcaacccc ggtagttttc cctaataaag
    19141 aactgctcaa gcaacgtctc tcccggttga tttggccgga aagcggcagg cacgtatttg
    19201 acagcagcac cgtggatgct gcagcacaaa aggttgtctc tcgtatgctg attcagatga
    19261 cggaaccttc ggctggggcg gaagttatta ccgacgataa tatgattgta gaatacaaat
    19321 acggcagagg gatttaaccg tcttaaaggg tttcaggcaa cgcaggtttt aggtaacgtc
    19381 ctgctagttc aaaaaaaccg catcacagca gtcgggacaa aatggtttaa acattttgtc
    19441 ccgaattctt attcctatat atagtggatt aacaaaaatc aggacaaggc gacgaagccg
    19501 cagacagtac aaatagtacg gaaccgattc acttggtgct tcagcacctt agagaatcgt
    19561 tctctttgag ctaaggcgag gcaacgccgt actggttttt gttaatccac tataccacga
    19621 attacggtgt aaaaatttat atgaccttat aaaatcaaat aagaatcgtt atcataacat
    19681 gattgtattt attgggtttt tttgggcgtt ttgccgatat ttacctttta atggtttttg
    19741 aaattcgcta aaatacgaaa ttattgtaga aattttgtta acggatttgg gtgtaaccat
    19801 gttgtccgct tactttcccg tctttgtctt tatcctcgtc ggcctcgcgg ccagcgtgct
    19861 gtttatcctg ctcggcacga ttttaggccc gaaacgccac tacgccgaaa aagacgcgcc
    19921 ttacgaatgc ggttttgaag cctttgaaaa cgccaggatg aagttcgacg tgcgctatta
    19981 cctcgtcgcc atcctcttta tcttgtttga tttggaggtc gcgttcatgt tgccgtgggc
    20041 agtcgtgttc aaagatttgg gcgcgtacgg cttctggtct atgctggtgt ttatcgtcgt
    20101 tctgacggta ggctttgttt acgaatggaa aaaaggtgcg ctggaatggg aatagaaggc
    20161 gttttgaaaa aaggtttcat caccaccagc gcggatacgg tgttgaacta tatgcgtacc
    20221 ggttcgttgt ggccggttac tttcggcttg gcctgctgcg ccgtggaaat gatgcacgcg
    20281 ggtatggcgc gttatgacct tgaccgtttc ggcatcattt tccgtccgtc cccacgtcag
    20341 gccgacctga tgattgtggc gggtacgctg accaacaaaa tggcacccgc cctgcgccgc
    20401 gtgtatgacc agctcgccga gccgcgctgg gtattgtcta tgggctcgtg tgccaacggc
    20461 ggcggctatt atcactattc ttattccgtt gtgcgcggtg ccgaccgcgt cgtgccggta
    20521 gacgtttatg tgccgggttg tccgccgact gcggaagccc tgatttacgg cctgattcag
    20581 ctccaacaaa aaatcaagcg cacttccacc atcgcgcgtg acgagtaagg agaggacgat
    20641 atggcaagca ttcaaaactt atacgagacc gttgtcggcg tgcttggcga tcaggcaagc
    20701 aaagtcattt ctgctttggg cgagattacc gttgagtgtc tgcccgaaca ctatgtttca
    20761 gtgatgacta cgttgcgcga ccatgaagag ttgcatttcg agcttctagt tgacttgtgc
    20821 ggcgtcgatt acagcactta caaaaacgaa gtatggcagg gcaaacgctt tgccgtcgtc
    20881 agtcagttgc tttccgttaa aaacaatcaa cgcatccgcg tgcgcgtctg ggtttcagac
    20941 gacgacttcc ccgtagtcga atctgtagtc gatatttaca acagcgcgga ttggtacgaa
    21001 cgcgaagcct tcgatatgta cggcatcatg ttcaacaacc atccggactt gcgccgcatc
    21061 ctgaccgatt acggtttcgt cggacatccg ttccgcaaag acttcccgat ttccggctat
    21121 gtggaaatgc gttacgacga agagcaaaaa cgcgtgattt accaacctgt taccattgag
    21181 ccgcgcgaga tcacgccgcg tatcgtccgt gaggagaact acggtggcca ataaattaag
    21241 aaactacacc atcaacttcg gcccgcaaca ccctgcggcg cacggcgtat tgcgtatgat
    21301 tttggagttg gaaggcgaaa ccatcgtccg tgccgacccg catatcggtc tcctgcatcg
    21361 cggcaccgaa aaactggcgg aaaccaaaac ctatctgcaa gccctgcctt atatggacag
    21421 gctggactac gtttccatga tggtcaacga gcaggcatac tgcttggcgg tagaaaaact
    21481 cgccggaatt gatgtaccta tccgcgccca atacatccgc gtgatgttcg ccgaagtaac
    21541 gcgcatcctc aatcacttga tgggcatcgg ttcgcacgca ttcgacattg gtgcgatgac
    21601 cgccatcctc tacgccttcc gcgaccgcga agagctgatg gacttgtacg aagccgtgtc
    21661 cggcgcgcgt atgcacgcag cctacttccg tcccggcggt gtttaccgcg acctgcccga
    21721 cttcatgccc aaatacgaga gcagcaaatt ccgcaatgcc aaagtattga agcagctcaa
    21781 cgaatcccgc gaaggcacga tgctcgactt tatcgatgcc ttctgcgaac gtttcccgaa
    21841 aaacatcgac acactcgaaa ccctcctgac cgacaaccgt atttggaaac agcgtaccgt
    21901 cggcatcggc gtcgtctccc ccgaacgtgc catgcaaaaa ggctttaccg gcgtgatgtt
    21961 gcgcggttcg ggcgtggaat gggacgtgcg taagacacag ccttacgaag tgtacgacaa
    22021 aatggatttc gacatccctg tcggcgtgaa cggcgactgc tacgaccgct acctctgccg
    22081 tatggaagaa atgcgccaat ccgtacgcat catcaaacaa tgctccgagt ggttgcgtgt
    22141 caatccgggt ccggtcatta ccacaaacca caaattcgct ccgcccaaac gtaccgaaat
    22201 gaaaacaggt atggaagacc tgattcacca tttcaaacta tttaccgagg gtatgcacgt
    22261 tcccgagggc gagacctaca ctgctgtcga acacccgaaa ggcgagttcg gcgtttacat
    22321 catttcagac ggcgcaaaca aaccctaccg cctgaaaatc cgcgcacccg gcttcgccca
    22381 cctgcaaggt atggacgaaa tggcaaaagg ccacatgctc gccgacgtcg ttgccatcat
    22441 cggtacgcag gacatcgtat tcggggaggt tgaccgataa tgttatccgc agagtcctta
    22501 aaacaaatcg acacagaact ggcgaaatat cccgccgacc aacgccgttc cgccatcatg
    22561 ggtgcgttgc gtatcgccca aaccgaaaaa ggctggctcg cccccgaaac catcgctttt
    22621 gttgccgact atatcggcat cacgcctgca caagcctacg aagtcgctac cttctacaat
    22681 atgtacgatc ttgagcctgt cggcaaatac aaactgaccg tttgtaccaa cctgccctgc
    22741 gccctgcgcg gcggtatggc taccggcgaa tacctcaaac aaaaactcgg tatcggctac
    22801 ggcgaaacta cccctgacgg caagtttacc cttgtcgaag gcgaatgcat gggcgcatgc
    22861 ggtgatgccc ccgttatgct ggtcaacaac cacagcatgt gcagctttat gaccgaagaa
    22921 gcgattgaga agaaactggc ggagttggag taggtcgtct gaaacgacga tttaaacgta
    22981 ggtcggatac ttgtatccga cagagtgggt aaaaaggcaa aatgtcggat ttaagaatcc
    23041 gccctactga aataccgaaa tgccgtcatt cccgcgcagg cgggaatcca ccggtaagat
    23101 tcggtttctg aatttaataa gacattgctt accattgagg atggattctc gcctgcgcgg
    23161 gaatgacgac agacaagcaa gtggtcgaga tccaacaaaa acgattaaag gtcgtctgaa
    23221 aatatcgatt tgataaacta gattttattt cagacgacgt tacaagccgg tacacaaaga
    23281 catcttaagg tcgtctgaaa cagcggccgc aaccgatacg aaaacaaaca ggcacaccaa
    23341 aaatggctat ttaccaatca ggcgtgattt ttgaccaagt ggataccgcc aatcccgatt
    23401 gctggacatt ggacgaatac gtcaaacgtg gcggttatac cgccctgcgt aaaatcctgt
    23461 ccgaaaacat ctcgcaaacc gatgtgattg acgaagtcaa aacctccggc ttgcgcggtc
    23521 gtggcggtgc gggcttcccg accggtttga aatggagctt tatgccccgt tctttccccg
    23581 gcgaaaagta cgtcgtttgc aacaccgacg aaggcgagcc gggtacattt aaagaccgcg
    23641 acattattat gttcaacccc catgccctga ttgaaggcat gattatcgcc ggttacgcga
    23701 tgggcgcgaa agccggttac aactatatcc acggcgaaat ttttgaaggc taccaacgct
    23761 ttgaggccgc tttggagcag gcgcgtgccg caggcttttt gggtaaaaat attttgggtt
    23821 cggattttga attcgaactc ttcgcccacc acggctacgg tgcatacatc tgcggcgaag
    23881 aaaccgcatt gcttgaatcg ctggaaggca aaaaaggcca gccgcgcttt aaaccgccat
    23941 tccctgcttc gttcggcctg tacggcaaac cgactaccat caacaatacc gaaactttct
    24001 cctccgtttc attcattatc cgtgacggcg gacaggcatt tgccgataaa ggtattccga
    24061 atgcaggcgg taccaaatta ttctgtattt ccggccatgt cgagcgtccg ggcaactatg
    24121 aagtgccatt gggcacaccg tttgccgaag tcttgaaaat ggcaggcggt atgcgcggcg
    24181 gtaaaaaact caaggccgtt attcccggcg gttcgtccgc gcccgtattg cctgccgaca
    24241 tcatgatgca gaccaatatg gactatgact ccatttccaa agcaggctcg atgctcggtt
    24301 ccggcgcgat tatcgtgatg gacgaagacg tgtgcatggt caaagccctc gaacgcttaa
    24361 gctactttta ctacgacgaa tcctgcggcc aatgcacccc gtgccgcgaa ggtacaggct
    24421 ggctctaccg catcgtccac cgcatcgtag aaggcaaagg taaaatggaa gatttggatt
    24481 tgctggattc cgtcggcaac caaatggcag gccgcaccat ctgcgccctt gccgatgccg
    24541 ctgttttccc tgttcgcagc tttaccaagc atttccgtga tgagtttgtg tattacatcg
    24601 aacacggcgg gccgatgaaa gagcataagt ggggagggtg gtaatggtgg aagctaaaat
    24661 ttttattcta tacggtgcag ccaacaaagg taagagtacg acactcaata cgctttttaa
    24721 tcagatttgt tggaaatttt ctaaatttct agtctttttt gaaagacatg gaaatggctt
    24781 agattttgtt gcagtatttg atcatgaagg tcagagaatt ggtttttatt catctggtga
    24841 taatgaatac gaggttagga gaaatttata caaactttat tcgcataatt gtgattttat
    24901 ttttggcacg tcaaggacac ggggtggtag ttgcgatgca gtaggatgtt atgcagagtt
    24961 attgcatggc gatgtaaata taattaattg gtgtgaaaag tttgagccta cagatgaaga
    25021 caatgagcgt gctgttaaag agttatttaa gtcatttaaa aatataataa atgagttata
    25081 gttttagttg gttttatatt ggttaaaagc aaaatgctaa aaatttaact ttgccgtcat
    25141 tcccgcgtag gcgggaatcc atagtggaat ttacagaacc cgatatttga aaagcagttg
    25201 ccgaaattca aaaaatggat tcccgcctac gcgggaatga cggcaaggtg gcagtaaacg
    25261 ttttaaacag tattgattgt caatgaaact caaaaggccg tctgaaaccc atttttcaga
    25321 cgacctccat aagattattt atcaaatacc cgtaactagg aacgaaccat gttacaaatc
    25381 gaaatcgacg gcaaacaagt atctgtggag cagggcgcga cggtaattga agccgcgcac
    25441 aagctcggta cttatattcc gcatttctgt taccacaaaa aactttccat cgccgccaac
    25501 tgccgtatgt gtctggtgaa cgtagaaaaa gccccaaaac ccctgcctgc ctgtgccacg
    25561 ccggttacag acggcatgat tgtgcgtacg cattcggcaa aagcccgaga ggcgcaggaa
    25621 ggcgtgatgg agttcctgct catcaaccat ccgcttgatt gtccgacctg cgaccaaggc
    25681 ggcgaatgcc agttgcagga tttggcggtg ggctacggca aaaccaccag ccgctacacc
    25741 gaagaaaaac gttccgtcgt cggcaaagac atggggcctt tggtttccgc cgaggaaatg
    25801 agccgctgta tccactgcac ccgctgcgtt cgtttcactg aagaaatcgc cggtttgcaa
    25861 gaaattgcga tggtgaatcg cggcgaacac tccgaaatca tgccctttat cggcaaaacg
    25921 gtggaaaccg agctgtcggg caacgtcatc gatttgtgtc ctgtcggcgc attgaccagc
    25981 aaaccgttcc gcttcaacgc gcgtacttgg gaattgaacc gccgcaaatc tgtttccgcc
    26041 cacgatgctt tgggcagcaa cctgattgta caaaccaaag accatactgt ccgccgcgtg
    26101 ttgccgttgg aaaacgaagc gattaacgaa tgctggctgt ccgaccgcga ccgttttgcc
    26161 tacgaaggcc tgtatcacga aagccgtctg aaaaacccga aaatcaaaca gggcggcgag
    26221 tggatggacg tggattggaa aaccgcgttg gaatatgtcc gcagcgcgat tgaatgtatc
    26281 gccaaagacg gcaagcaaaa ccaagtcggc gtttgggcca atccgatgaa tacggttgaa
    26341 gagctgtatc tggccaaaaa actcgccgac ggtttgggtg ttaaaaactt tgccacccgt
    26401 ttgcgccaac aagacaaacg tctttcagac ggccttaaag gtgcacaatg gttgggacaa
    26461 agcattgaat ctttggctga caacgatgcc gtattggtag tcggtgcgaa cttgcgcaaa
    26521 gaacagccgc tcctgaccgc ccgcctgcgc cgcgccgcca aagaccgtat ggccttgagc
    26581 gtattggccg gcagcaagga agagttgttg atgccgcttc tctctcaaga agccgcacat
    26641 cccgacgagt gggcaggccg tctgaaaaac ctgtctgcca atgcggaaca cgccgttacc
    26701 gccagcctga aaaatgctga aaaagcagcg gtgattttgg gcgcggaagt gcaaaaccat
    26761 cctgattacg ccgccattta tgctgccgcg caagagctgg cagccgcgac cggcgcagtg
    26821 ctgggtattt tgccgcaagc cgccaacagc gttggtgcgg atgtcttggg cgtgaactcg
    26881 ggcgagagcg ttgccgaaat ggcaaacgcg ccgaaacagg cggtcttgct actcaacgtc
    26941 gaaccggaaa tcgatacggc ggacggtgcg aaagccgtgg ccgcgttgaa acaggcgaaa
    27001 agcgtgatgg cgtttacacc gtttgtcagc gaaacgctgc tggatgtgtg cgacgtgttg
    27061 ttgccgattg cgccgtttac cgaaacctcg ggcagcttca tcaatatgga aggccgtctg
    27121 caatccttcc acggcgtggt acaaggcttc ggcgattcgc gtccgatgtg gaaagtattg
    27181 cgcgtattgg gcaacctgtt tgacctgcaa ggttttgaat accacgatac cgctgcgatt
    27241 ctgaaagatg cgctggatgt agaaagcctg ccgtccaaac tggacaaccg caacacatgg
    27301 acaggggagg gcgttcagac gacctcagac cgcctcgtcc gtgtcggcgg cgtcggtatt
    27361 tatcacactg attctatcgt gcgccgttcc gcaccgttgc aagaaaccgg ccatgccgcc
    27421 gtgcccgccg cgcgtgtcaa tccgaacact ttggcacgct tgggcctgca aaacggacaa
    27481 actgctgtcg ccaaacaaaa cggcgcaagc gtatcggttg ccgtcaaagc cgatgccggt
    27541 ttgcctgaaa acgtggtgca tctgccgctg cataccgaaa atgccgcgct gggtgcgttg
    27601 atggacacta ttgaactggc gggagcttga ttatgcagga atggttccaa aacctctttg
    27661 ccgcaacgct cggtctgggc gatttgggta ttaccgtagg tttggtggta tccgtcatcg
    27721 tcaaaatcgt gattatcctg attccgctga ttctgaccgt tgcctacctg acgtatttcg
    27781 aacgtaaagt catcggcttt atgcagcttc gtgtcggccc gaacgtaacc ggcccgtggg
    27841 gtctgattca gccgtttgcc gacgtgttca aactcttgtt taaagaggta acccgtccga
    27901 agctgtcaaa caaagccctg ttctacatcg gcccgattat gtcgctcgcc ccgtctttcg
    27961 cggcgtgggc agtgattccg ttcaacgaag aatgggtgct gaccaacatc aatatcggcc
    28021 ttttgtacat cctgatgatt acctcgctgt cggtttacgg cgtaatcatc gcgggctggg
    28081 cttccaactc caaatattcg ttcttgggtg caatgcgtgc ttccgcacaa agcatttcct
    28141 acgagattgc catgagtgcc gcgctggtgt gtgtcgtgat ggtgtcgggc agcatgaact
    28201 tctccgacat cgttgccgcg caggcaaaag gtatcgcggg cggttccgta ttctcgtgga
    28261 actggctgcc gctgttccca atcttcatcg tctatctgat ttccgccgtt gccgaaacca
    28321 accgcgcacc gtttgacgtg gcagagggcg agtccgaaat cgttgccgga caccacgttg
    28381 aatattccgg cttcgcattc gcgctgttct tccttgccga atacattttc atgattctga
    28441 ttgccgcgct gacatcgctg atgtttctcg gcggctggtt gtctccgttc ccgcaaagct
    28501 ggggctttat cggtacgcct tccgcattct ggatgtttgt gaaaatggcg gcagtgttgt
    28561 actggtacct gtggatccgt gcaaccttcc cgcgctaccg ttacgaccaa atcatgcgtt
    28621 tgggctggaa agtgctgatt ccgatcggct tcgcctacat cgtgattttg ggcgtgtgga
    28681 tgatttcacc gctgaatttg tggaaataag tttcagacgg catcttgagg ccgtctgaac
    28741 aaagcgattt tgaataccta acgaaatccc tgttttgagg gaacataata tggctaactt
    28801 agtaaaaacc tttctgctcg gcgagttggt aaaaggcatg ggcgtaacgc tcaaaaactt
    28861 ttttgcccgc aaagacacaa tttatttccc cgaagagaaa acgccgcaat ccgtgcgttt
    28921 ccgtggcctg cacgcgcagc ggcggtatcc gaacggcgaa gagcgctgta tcgcgtgtaa
    28981 attgtgcgag gcagtttgtc cggcaatggc gattaacatt gaatcggaag aacgcgaaga
    29041 cggcacccgc cgcaccaagc gttacgatat cgacctgacc aagtgcatct tctgcggttt
    29101 ctgcgaagag gcctgcccga ccgatgcgat tgtggaaacg catatttttg aataccacgg
    29161 cgagaaaaaa ggcgacttgc acatgaccaa gccgatcctc ttggcaatcg gcgacaaata
    29221 cgaagctgaa atcgccaaac gcaaagccgc tgatgcgccg tatcgttaag gagcagacga
    29281 atgacttttt ccgcgattct gttctatatc cttgccgcca tcgtcctata cggcgcgctg
    29341 cgtaccgtta cagcgaaaaa ccctgtccac gccgctttgc atctggtgtt gaccttctgc
    29401 gtgagcgcga tgctttggat gctgatgcag gctgagtttt tgggcgtgac gctggtggtg
    29461 gtttacgtcg gcgccgtgat ggtgttgttc ctgttcgtcg tgatgatgtt gaacatcgac
    29521 attgaagaaa tgcgtgccgg tttctggcgg cacgcgcctg ttgccggtgt ggtcggcaca
    29581 ttgttggcag ttgccctgat tctgattctg gtcaatccga aaaccgacct tgccgcattt
    29641 gggctgatga aagacattcc cgccgattac aacaatatcc gcgatttggg cagccgtatt
    29701 tataccgatt atctgctgcc gtttgaattg gcggcggtat tgctgctgtt gggtatggtg
    29761 gccgcgattg cgctggttca ccgtaaaacg gttaatccga aacgtatgga tcctgccgac
    29821 caagttaaag tacgcgccga ccaaggccgt atgcgcttgg tgaaaatgga agccgtgaaa
    29881 ccgcaaaccg aatctgccga agaaagcgaa gtttcagacg acctcaagcc gaaagaggag
    29941 ggcaaagcat gattaccttg acgcattatc tggtattggg tgcgctcctg ttcggtatca
    30001 gcgcgatggg tatcttcatg aaccgcaaaa acgtgctggt attgttgatg tccattgagc
    30061 tgatgctttt ggcggtgaac ttcaacttta tcgccttttc gcaacatttg ggcgatactg
    30121 ccggacaaat tttcgtattt ttcgtactga ccgttgctgc tgccgaatct gccatcggtt
    30181 tggcaattat ggtgctggtg taccgcaacc gacaaacgat taacgttgcc gatttggacg
    30241 agttgaaagg gtaaaggtag gttgggtcga gacctgacaa gacaccgatg ccgtctgaaa
    30301 acccgatagg aaaaacgatg aaatccatag acgaacaaag cctgcataat gcccgccgcc
    30361 tgtttgaaag cggcgacatc gaccgtatcg aagtcggtac caccgcgggc ctgcaacaga
    30421 ttcaccgtta cctgttcggc ggcttatatg attttgcggg tcaaatcagg gaagacaaca
    30481 tttccaaagg cggttttcgt tttgccaacg ccatgtattt aaaagaggct ttggttaaaa
    30541 tcgagcagat gcccgagcgg acttttgaag aaatcatcgc caaatatgtt gaaatgaaca
    30601 ttgcccatcc gtttttggag ggtaatggca gaagtacccg catctggctg gatttggtgc
    30661 tgaaaaaaaa cctgaaaaaa gtcgtgaact ggcaaaatgt aagtaaaacc ctgtatttgc
    30721 aggcaatgga acgcagcccc gtcaacgatt tagaactgcg ctttctgtta aaggacaacc
    30781 tgactgacga tgtggacaac cgtgaaatca tctttaaagg tatcgagcag tcgtattatt
    30841 acgaagggta tgaaaaaggc tgagggtcgt ctgaaaagcg atttcagact gtttcagacg
    30901 acctgattcg gtaggtgatc agacgggagc ggatgagaaa agaaattctg ggtaagaata
    30961 atccggtctg aaatattgga agaagaatga tggataaaaa tcagttagaa caagaatttc
    31021 ataaagccat gttaaatatt tatcaggagg ctttgaattt gccgcaacct tacaaggcga
    31081 cacgattttt acaaattgta aatgaatttg gtggtaaaga ggcggcggat aaattattaa
    31141 gtacggggga aaagaagact cagaccggtt ttacagagct gattttgagt ggtggcggag
    31201 tccacgcctt gaaatacagt atggaatatc tggtgttaca aaagccgtgg tgtgatttat
    31261 ttactgaaga gcaattagct gtggcacgca aacgattgga gcgtgttgga tttgtttctc
    31321 cgaagtaatt ttgtacgaaa caaacataga tttttaaatc aatcggattc aatcaaatga
    31381 acgacatgac tttatatctc atcattgccc ttgtgccttt ggcaggctcg ctgatcgcgg
    31441 gtttgttcgg caacaaaatc ggacgtgccg gtgcgcatac ggttacgata ctcggcgtgg
    31501 cggtgtccgc cgtgctgtcg gcttatgtgt tgtggggctt tattgacggc agccgcgcca
    31561 agtttgacga aaacgtctat acctggctga caatgggcgg cttggatttc tccgtcggct
    31621 ttttggtcga tacgatgacg gcgatgatga tggtcgtggt caccggcgta tcgctgatgg
    31681 tacatatcta taccatcggt tatatgcacg atgaaaaaat cggctaccaa cgcttcttca
    31741 gctatatttc tttgtttact ttcagcatgt tgatgctgat tatgagcaac aacttcatcc
    31801 agctcttctt cggttgggaa gcggtgggct tggtatcgta tctcttgatc ggtttctatt
    31861 tcaaacgccc gagcgcaaca tttgccaacc tgaaagcctt tttgatcaac cgtgtcggtg
    31921 acttcggctt tttgctcggt atcggcttgg tgcttgccta tttcggcggc agcctgcgct
    31981 atcaagatgt attcgcttat ctgcccaacg tccaaaatgc caccatccag cttttccccg
    32041 gtgtggaatg gtctttgatt accgtaacct gcctgatcct gtttgtgggc gcgatgggta
    32101 aatcggcaca attcccactg cacgtttggc tgcctgattc gatggaaggc ccgaccccga
    32161 tttctgcatt gattcacgcc gcaaccatgg ttaccgccgg tctgttcatg gtatcgcgta
    32221 tgtcgccgat ttatgagatg agtagcactg cgctgtctgt catcatggtg attggtgcga
    32281 ttaccgccct gtttatgggt ttcttgggcg tgattcaaaa cgacatcaaa cgtgtggttg
    32341 cgtattccac cctgtcgcaa ttgggctata tgaccgtggc tttgggcgcg tccgcctatt
    32401 ccgtggcgat gttccatgtg atgacccacg ctttcttcaa agccttgttg ttcttggcgg
    32461 caggcagcgc gattatcggt atgcaccatg accaagacat gcgccacatg ggcaatctga
    32521 aaaaatacat gccgattact tggctgacca tgctgatcgg taacttgtcg ctgatcggta
    32581 cgccgttctt ctccggcttc tattccaaag attcgattat cgaagcggcg aaatacagca
    32641 ccctgccggg cagcggcttt gcctattttg ccgtcctcgc cagcgttttt gttactgcgt
    32701 tctacgcatt ccgccaatac tttatggtgt tccacggcga agagaaatgg cgcagcttgc
    32761 ctgaacatca tgacgatcat catggcgaag aacatcacag cttgggcaaa aacgacaatc
    32821 cgcacgaaag cccgttggtt gttaccctgc ctttgatttt gcttgccatt ccgtccgtca
    32881 tcatcggcta ccttgccatc gagcctatgc tttacggcga tttcttcaaa gatgtgattt
    32941 tcgtcaatac cgacgcgcat ccgaccatgc acatcatgaa ggaagagttc cacggcgcat
    33001 tggcaatggt gtcgcacagc ctgcattcgc ccgtactcta ccttgctatc gcaggcgtgt
    33061 tgagcgcatg gcttttgtac gtcaaactgc cgcacctgcc agcgaaaatt gcacagacgt
    33121 tccgtccggt ttacgttttg tttgaaaaca aatactacct cgacgccctg tatttcaacg
    33181 tcttcgctaa aggcacgcgc gcactgggta ccttcttctg gaaagtcggc gataccgcca
    33241 ttatcgataa cggcatcgtc aacggctctg ccaaactggt cggcgcgatt gccgcgcaag
    33301 tgcgtaaagc ccaaaccggc tttatctaca cctacgccgc cgctatggta ttcggcgtat
    33361 tggtactgct cggcatgacc ttctggggat tgttcagata aaggcggagt ttcagacgac
    33421 ctgttcatag ttttgtagag gtcgtctgaa aagtttgaga agtgggcatt aagtcaaagg
    33481 gtggaacaaa atggtaccca acaggcgtga aatagccaac atgcaaatta tctgtttcct
    33541 aaatttttta ggcaatctca acaaatatag aggagtcaaa agggatgaca cagttatttt
    33601 tacattcaga tacaccaaat gagaaggaac tgatttcaat atatgagaaa gctgtttcag
    33661 aggcagtaga gctgtatatt ttctctgcgt atctcactca ttgggatgta aaaaataagc
    33721 tcaatagcaa attgcaagag tttaaattta tttttggaca agatttcgga ttgtctaaaa
    33781 aagaggctat tcggaaagtg ttgaaatggc ttccgtccca tttgaaattc acactgatgg
    33841 tagctcaagg cattcagggt tttcatccta aagctgtatt ttggaagaat gataagaatg
    33901 aatattatgc tttaatcggt tcttcaaatt tgactcatgc tgcgtttaat agcaattatg
    33961 aagcaaatat tttgactaaa atttccgagc aggattttat aaaagtcaaa tcttgggctg
    34021 atgaaattgc gatgaaatct atcccagtat cggaagattg gcttgaggag tatcaggaag
    34081 ctgaaattaa ttataagaaa tcaactgtta gccaatcatt gatggataag ttatttatgg
    34141 aaatgccaaa ttataatcaa gaactgattg cagcacggag aaaacagatg agaaaccatc
    34201 aaactgtgtg taatcaatta aaaagtctta ttaagcaatg tgctgcagga aagatagaca
    34261 atgatgagtt ttatgtggaa tttaataaat tatggtcttg gaaaagcgaa aataaaggag
    34321 aaggggtagg taatcgattt caagatcaaa cgtggaaaag gaccggaaag tcttcagatt
    34381 ttagaaaatt atgcattgct atccaatcag tttttgatgc accacttgct gagagagata
    34441 atgttgttgc caagcaaatt gattggctaa aagaatgtgg agtttccact cgtggttcag
    34501 ttttttctga aatgctttgt caagaatatc cagatagata tccagtgtta aacgctccta
    34561 ttaaaaaatt tttagaaaaa aataaattta agtctgcaaa aggagcaagt gaaggctcta
    34621 gatatattga tttaagtatg aagttaagag ctttactagc aatgcagtca gaaataaaaa
    34681 atttggctga attagatgtt ttagtgcagg cagaatatcg cgatagtaca gatattgatt
    34741 gggagtgagt aaagagggga gagagtattc atcccttttt cagacgacct cctgaaacgt
    34801 cgtctgacaa actaacccgc actacgatat ttttatttta accacaggtt aaccactatg
    34861 ttttccaact acctactcag cttggcaata tggataccca tcgccgcagg tgtgctggtt
    34921 ttgtcgaccg gtaaggacag ccgtgcgccg ctggcgcgtg tgcttgcctt tatgggtgcg
    34981 cttgccggtt tcttggtaac gctgcccctg tttaccggtt tcgaccgttt gagcggcggc
    35041 tatcaattta ccgagttcca cgagtggatt ccgctgctga aaatcaacta tgcattgggc
    35101 gtggacggta tttcggtgct ctttatcatc ttgaatgcgt ttattacgct gctggtggta
    35161 ttggccggtt gggaagtcat tcagaaacgt ccggcgcagt atatggccgc tttcctgatg
    35221 atgtcgggtt tgattaacgg cgcgtttgcc gctcaggatg cgattctgtt ttatgtgttc
    35281 tttgagggta tgctgattcc gttgtacctg attatcgggg tatggggtgg cccgcgccgt
    35341 gtctatgcgt cggtcaagct gttcctctat acgctgatgg gttcgctcct gatgctggtt
    35401 gctatggttt acctgtacta tcaaacaggc agcttctcta ttgtcgattt ccaaaacatt
    35461 aaacagattc cgttgggcgt acagcagctt ttgtttgcgg cgttcttcct gtcgtttgcc
    35521 gtaaaagtgc cgatgttccc cgtacacact tggctgccgg atgcccacgt tgaagcgccg
    35581 accggcggtt cgatggtgtt ggcggcgatt acgctgaaac tgggtgcgta tggtttcttg
    35641 cgctttatcc tgccgattat gccggatgcg gcacgctatt ttgcccccgt gatcatcgta
    35701 ttgagtctga ttgccgtgat ttatatcggt atggtggctt tggtgcaaac cgatatgaaa
    35761 aaactggtgg cgtattcgtc catcagccat atgggttttg taacgcttgg gatgtttttg
    35821 tttgttgacg ggcagttgga cgactgggca ttgaaaggcg cggtcattca gatgatttcc
    35881 cacggtttcg tgtcggcggc gatgtttatg tgcatcggtg tgatgtacga ccgcctgcac
    35941 acccgcaata ttgccgatta tggcggcgtg gtcaatgtga tgcctaagtt tgcggcgttt
    36001 atgatgttgt tcggtatggc gaacgccggt ctgcctgcga cttccggctt tgtgggcgag
    36061 tttatggtga ttatgggtgc ggtcaaagtg aatttctggg tcggcgcgct ggcggctatg
    36121 accttgattt acggtgcgtc ttataccctg tggatgtaca agcgcgtgat ttacggcgcg
    36181 atccacaatc cgcacgttgc cgaaatgaaa gacatcaact gccgcgaatt tgcgattctg
    36241 gcgattttgg cggttgtggt attgggtatg ggtctgtatc cgcaagcgtt tatcgaagtg
    36301 gtgcatcagg cggcaaacga tttgattgcc catgtggcac aaagcaagat ttgaggtgtg
    36361 taaatgaact ggtctgattt gaatttaatg cccgccatgc ccgaagtcgc gctgctgtcg
    36421 ctgctggtgt tattgttgct ggcagacttg tgggtcagtg atgacaaacg ccgttggacg
    36481 cattacggcg cgttggcaac ggtggcggtt acggctgtgg tgcagcttgc cgtttgggaa
    36541 cagggcagca cgtcttcgtt caacggcatg tatattgcag acggtatgtc gcgtttggca
    36601 aaaatggttt tatatgcctt gacctttgcc ctgtttgttt atgccaagcc ctacaaccaa
    36661 gtgcgcggta ttttcaaagg cgagttttac accctgtcgc tgtttgccct cttgggcatg
    36721 agcgtgatgg tgagcgcggg gcatttttta actgcctata tcggtttgga actcttgtcg
    36781 cttgcccttt acgccctgat tgccctgcgc cgcgattccg gctttgccgc cgaagccgcc
    36841 ttgaaatatt ttgttttggg cgcgctggca tccggcctgc tgctctacgg tatttctatg
    36901 gtttacggcg caaccggttc gctggaattt gccggcgtgc tcgcctcttc cttcaatgaa
    36961 gaagccaatg aatggctgtt gaaactgggt ttggtgttta ttgtcgtcgc cgttgcgttc
    37021 aaactcggcg cggtgccgtt ccatatgtgg gtgcccgacg tgtatcacgg cgcgcccact
    37081 tctgttaccg ccttggtcgg cactgccccg aaaatcgccg ccgtcgtttt cgctttccgc
    37141 atcctcgtta ccgggctggg aaccgtgcat catgactggt ctctgatgtt tgccctgctt
    37201 gccgccgcct cgctgctggt cggcaacctt gccgccatca tgcagaccaa tatcaaacgt
    37261 atgctcgcct attccaccgt atcgcatatg ggtttcatcc tgttggcgtt tatggcgggc
    37321 gcggtcggct ttgcggcggg cctctattac gccattacct acgcgctgat ggcggcggca
    37381 gggttcggcg tgttgatggt gttgtcggac ggggacgacg agtgcgaaaa catcagcgat
    37441 ttggcagggt tgaaccaaca ccgcgtatgg cttgcctttt tgatgctgct ggttatgttc
    37501 tctatggcgg gcattccgcc gctgatgggc ttttacgcca aattcggcgt gattatggca
    37561 ctcttaaaac aaggctatgt ttggttgtcc gtatttgccg tcgtgatgtc gctgattggc
    37621 gcgttctact acctgcgcgt ggtcaaagtc atgtattttg acgaatccgg ccgcgcccgt
    37681 cccaccgtcg gcggcaacaa tgccgcaaaa ttccttttga gcgtcaacgc gctgctgttg
    37741 gtgctgtggg gcattatgcc gcaaaccgtt atcgactggt gcgccaaggc gttggaaaac
    37801 acgctgtaag ccgccgcaac ggcagccgtg tcagaggctg ccgtttttgt taagatatgc
    37861 cgttccgcaa cgcagttcag acggcatcgc cgccgacaat gcccaaacag aaagcccgcc
    37921 atgaccgcat ccatgtacat ccttttgctg cttgccttga tttttgccaa cgcccccttc
    37981 ctcacgacca ggctgttcgg catcgtaccg ctcaagcgca aacatttcgg gcaccacttg
    38041 atcgagctgg cggcaggttt cgcgctgacc gccgttcttg cctacatcct cgaatcccgt
    38101 gcgggagcgg tacacgatca gggttgggag ttttacgcca ccgtagtctg cctgtacctg
    38161 atttttgcgt ttccctgttt cgtgtggcgg tatttttggc acacgcgcaa cagggaatag
    38221 gcaggcatag gaatgccgtc tgaaaccctt tcagacggca tttgtttcat tcaagtgcag
    38281 gccggcatcg ctgtgccggc acgtttcagc cggcgatata cgccggtttt aatatttgcg
    38341 ggcgactgca aattctgcca actgccgcag gcgcagggct ttgtcgccga agggttcgag
    38401 cagcgcgacc gcttcggcaa ccagtttgtg tgcgtatgag cgcgccgctt ccaagcccat
    38461 cagtttcaca taagtcggct tgtcgttgtc tgcgtctttg cccgccgtct tgcccaaagt
    38521 cgccgtgtcc gcttcacaat ccaacacatc gtcaatgact tggaacgcca gccccagttt
    38581 tgccgcataa tcgtccaata ccgccagact gtcttcagac agattcgggc aggacatcgc
    38641 ccccaataaa accgccgcac ggattagcgc acccgttttc aggctgtgca tctgttccaa
    38701 atcggcttga accatttgtt tgccgacatt cgccaaatcg attgcctgac cgcccgccat
    38761 gcccgcgctg ccgcccgctt tcgccaacac cgacaacatt gccaactggc gtgctgcggg
    38821 cagttctgtc ggacggctta acacgtcgaa ggcttgggtt tgcaaagcgt cgccgaccag
    38881 tagcgcggtg gcttcgccat atttgatgtg gcaggtcggt ttgccccgac gcaggctgtc
    38941 gttgtccatt gccggcatat cgtcgtgaac caacgaatag gcatggatca tttcgattgc
    39001 cgccattgcc tgttctactg cttcatgcac ggcttcgcct aattccgaag ctgccagaac
    39061 cagcatcggc cgcagacgtt tgcccccatc caaaaccgca taacgcatgg cttcgtgcag
    39121 tgtgtgcggt atttcgtttt cagacggcaa aaagcgttcc agcagcagct ctgtttgcgc
    39181 ctgcgccctc tgttgccacg ctttcaaatc attcgtcgga ttcaaggttc aactccttcg
    39241 gcccgtccgc gtccaaaacc tgtaatttct gttcgacttg cgccagcttg gtttggcagt
    39301 acctgaccag ctcgttgcct tcctgatagg cggcaagcgc gtcttccaag ggcatttcac
    39361 cctgcataga ctgcgtcagc gattcgaggc gcgacaaggc ttcttcaaac gatttcgggg
    39421 cgtttttctt catagtttcg ggagtttctg taaaaacgga attgtagcat ttctgaaaac
    39481 cggatgccgt ctgaaacagc aggatttcag atggcatggt ttttgccctg caaacggcaa
    39541 gaggttattt gagcagatcg tcggtaatgc gttgcaggaa ggtcagccgt tcggtgcgga
    39601 ttttaccggt ttgcgcggcg gctttgaagg cgcagccggg ttcggcgcgg tgggtgcagt
    39661 tgtggaagcg gcattgcccg acaaggtggc ggaaatcggg gaaatagcgc ggcaaatcgg
    39721 cggcttggag gtggtgtaaa ccaaattctt gcaaacccgg ggagtcgatg agttgggttt
    39781 cgccgttcaa atcataaagc cgggcgtggg tggtggtgtg ttttcccgag tcgagtgcgg
    39841 cggaaatgtc gccggtgcgg gcggtttggc tgcccaaaag ggcgttggtc agggtggatt
    39901 tgcccatacc gctctgcccg agcaggatgt tgctgtgccc ttgcagggcg gggcgcaggc
    39961 tgccggcgtt ttccagtgcg cgggtttcga tgacgggata acccagcgtt tcgtagaatt
    40021 tgagtttttc gcgccaaagg gcggtttcgg gcaggtcggc tttgttcagg acgatgacgg
    40081 cgcggatgcc ggcggcttcg gcggcaagca gggcgcgttg cagcagccgc acgctcggac
    40141 tcgggacggc ggcggttacg atgaggagtt gggtaacgtt ggcggcaatg agtttggttt
    40201 tccacgcgtc ttggcggtag agcaggcttt ggcgcggtaa aaaatcttca atcacaactt
    40261 gttcggcgtt gacggggctg atgcggacgc ggtcgccgca ggcgaaatcg acgcgttttt
    40321 tgcgggtgct ggcttcgtag gttgtgccgt cgggcgtgcg gacaatgtag cggcggccgt
    40381 agctggcggt aatttgggcg gtgtcgttca tggtttcttt ggggttgggt gtggaaatgc
    40441 cgtctgaaaa cgggtgttcg gacggcatcg gttcagtcgt gctgccactc gacgtgttcg
    40501 ttgaggaagc cgccgctctg gtgcgcccag agtttggcgt aaagcccgcg tttttcgagg
    40561 agttcggcgt gtgtgccttc ttcgatgatg cggcctttgt cgaggacgac gagcctgtcc
    40621 attgcggcga tggtggagag gcggtgggcg atggcgatga cggttttgcc gtccatcatt
    40681 ttgtcgaggc tttcttggat ggcggcttcg acttcggaat cgagcgcgct ggtggcttcg
    40741 tccaaaagaa gaatcggtgc gtctttgagc atcacgcggg cgatggcgat gcgctggcgt
    40801 tgaccgccgg agagtttcac gccgcgttcg ccgacgtgtg cgtcgtagcc gcgccgccct
    40861 ttggcatcgg aaaggtcggg gatgaagccg gcggcttcgg cgcgttcggc ggcagaaacc
    40921 atttcggcat cggtcgcgtc ggggcggccg taaataatgt tgtcgcgcac ggaacggtgc
    40981 agcagcgagg tatcttgcgt gaccaaaccg atttgggcgc gtaaagattc ttgggtgacg
    41041 ccgcttatgt cctgcccatc aatcaaaacc gtgccgcttt gcggttcgta gaagcgcaaa
    41101 agcaggttga cgatggtgga tttgcccgcg ccgctgcgtc cgatcaagcc gactttttcg
    41161 cccgggcgga tggtgaggtt gaagccgttg agcagcggtt tgcccgcttc gtaggagaaa
    41221 tcgacgtgtt cgaacttgat ttcgccttgc gacactttca gcggcagggc gttcggcttg
    41281 tcgaggatgg tgtgcggttt ggacagggtt gccatgccgt cgccgacggt gccgatgttt
    41341 tcaaacagcc gcgcggattc ccacataatg tattgcgaca aaccgttgac gcgcaacgcc
    41401 atggcggtgg ctgtagcaac cgcgcccacg ccgacctgcc cgttgtgcca gagccagatg
    41461 cccagtgcgg cggtggagag ggtcagggag gtgttgacga tgaagctgca cgaatgcagc
    41521 agcgtcgcca gccgcatttg ggcgcgcacc gtaaccataa attcttccat cgactgcttg
    41581 gcataggcgg cttcacgcgc gccgtgggag aagagtttga cggtggcgat attggaatag
    41641 gcatcggtaa tgcggccggt catcagcgag cgggcatccg cctgccatgc ggcggtttgc
    41701 cccaatttgg gaatcagcag gcgcatcacc gaagcgaaac cgacaatcca gccgataaag
    41761 ggcagcagca gccatgagtc gagcgaggcg agaatcacgc cggaggtaat gaaatacacc
    41821 gacacataaa cgaccatatc ggcaaccgtc atcaccgcgt cgcgcaacgc cagcgcggtc
    41881 tgcatgactt tggcggacac gcgtccggca aattcgtcct gataaaaacc gaggctttgg
    41941 ttcagcatca ggcggtggaa gttccagcgc aggcgcatgg ggaacacgcc ctgaagggtt
    42001 tgcaggcgca cgttggacgc ggcaaacgcc cacgcaaccg aaaacaccat catcgccgcc
    42061 attgccgcca gttcccaacc tttttcggca aacagttcgg tgggcgcgta tttgccgagc
    42121 cactccacga ttttgcccat aaattgaaaa accaaggctt ccataatgcc gatgccggcg
    42181 gtcagcgcag ccagggcggc tatccatttc cgcacgccgg tcatgctgct ccagacaaac
    42241 cgccacaagc ctttttctgg cgttttcggg gcggcttcgg gataagggtc gattcgggac
    42301 tcgaaccagg aaaatatttt gttcaacatt gttttcgatt tcggtaaaac agtttcagac
    42361 ggcatcaaac acaatgccgt ctgaaaggaa ggacaataac gccattttac gggaaaagcc
    42421 gtcgggaaga cagcgcgggg cggaaacgca gggtttcgtc agggcaaacg ccgcgccgcc
    42481 ttcagacggc attatttcag caggtttttc aaagcaaggc gcacgccttc gcccacgtcc
    42541 gtcccctccg gaacgccttt gaccgccgct tttgcttcgc gttcgctgta acccagcgca
    42601 agcagcgtgc tgacgatgtc ttccgtttcg tcggcggcgg gtgcggcggc aaacagcccg
    42661 tccgttaccg tatgcgcgac cagcttgccg cgcagttcca agaccatacg ttcggcggtt
    42721 tttttgccga ttcccggcgc ggaagacagg cgtttcacgt cttcttcggc aaccgcccgc
    42781 gccagctcgt ctgccgtcat cgccgacaaa atgcccaaag ccgttttcgc gccgatgccg
    42841 ccgaccttaa tcagttggcg gaaggtcttg cgttcttccg cagtggcaaa accaaataaa
    42901 agatgtgcgt cttcccgaat gataagctgg gtaaacagtt gtacgctttc acccacgggc
    42961 ggcaggttgt agaaagtctg catcgatacg tcggcctcat agccgacacc gttgacatcg
    43021 atgacgattt gcggagggtt tttttcaacc agtttgccgg tcagtctgct gatcatgtgt
    43081 gccgaatcct gaagtgtcgg gtgcaaaatg ccgtctgaaa ccggttcggg cttcagacgg
    43141 cacggattgt atcaaattca gtcgtcgcgg cgggaggaaa tcacgcggcc ggtacgggca
    43201 tcgacaacga ctttgtattc ctgtccgttt ttgacgattt cgacatcata gtgcggacgg
    43261 ccgttgtcgt gttcgagatc gatgtcggtg attttgccgc cgacacgcgc caacgctgct
    43321 ttttcggctt gggcgcggct gatgattttg tcttgtttgc tgtgttggtg tgcggcgtgt
    43381 ccgtggtcgt catcgccgtg tccgtcgtgg tgggcgagtg cgggggcgga aatgcccatc
    43441 agtgcggttg cggcggcggt caagagaagg tgtttgatgt tcatattttg cctttgtaaa
    43501 tcgtgggttg gaaaatgtgg atattaataa ggtatcaaat aaccgtcagc cggcagtcaa
    43561 taccgcccga accataccgc gcgcctgagc ttcggcttcg gcggcgcgtt cctgcgagga
    43621 aaacggcccc attttgacga catattcgta atggcgtttt tcaaccgata ggttcgggtt
    43681 tgatgccgat gaagccaggt tttgggcggc ttggttcaga taggcttgtg cttcgtgttc
    43741 cgtaccgaaa gatttcaagt cgatgaagat gtctttgttt tcggcaacca gtgcggattg
    43801 gcccgggacg atttgttcga ttttgacgtg cgccgtccct tggctgacaa agcccaattt
    43861 ttgcgcggcg gctttggata cgtcgatgat gcggttgccg tggaagggac cgcggtcgtt
    43921 gacgcggacg atgacgcttt tgccgttttt ggtattggtt acgcgcacat agctggggat
    43981 gggcagggtt ttgtgggcgg cggtaaaggc gttcatatcg tatcgttctc cgccggaagt
    44041 tttgcgcccg tgaaacctac cgccgtacca cgaggcgttg ccggtttgcg tgaattcggc
    44101 gacttggttt ttcggcgtgt agcgttttcc ggcgactttg tagctgcggt tggcggaggc
    44161 gtgcagtttt tctgccttga ccactgcgtc ggcggatgcc gtctgaaggg agtgtgtgcc
    44221 gaatgcggcg gtgagaagga aaagggtttt tcgggttaaa gtcaaaacgt gttccgttct
    44281 tgagttgaag acgaatgggc atcatgcccg ccggatacgt tccgaaccgc cgtacagtgc
    44341 ggacggcggt tcggaatgtg tccggatagg ttttcagacg gcatgaactt gcgttcaaac
    44401 gccgcctgcg taaccgtgtt gccgccacgc ttcaaagaga atcacggcaa cggtattgga
    44461 aaggttcata ctccgactgc cgggctgcat gggcaggcgg attttttgcg cggcgggcag
    44521 gctgtcgagg atgtcggcag gcagtccgcg cgtttccggc ccgaacagta aaacgtcgcc
    44581 tttttgaaac gcggtttcat cggggcgcgc cgtgcctttg gtggtcaggg cgaaaatgcg
    44641 cctgcctgcg agtgccttga ggcagtcgtc gaagttttcg tgcaccgtca ggctggcgaa
    44701 ctcgtggtag tcgagcccgg cgcgtttcat tttggcggaa tccaatggga agccgagcgg
    44761 tttgacaagg tgcaaatccg cgccggtatt ggcgcacagg cggatgatgt tgcccgtgtt
    44821 cggcgggatt tccggctggt ataaaacgat ggtaaacata aatatcaatc acttataggc
    44881 gcgtaacctt gccacaaggc ggatggggtg tcaaaaaatt tagttatttt ttcattggcg
    44941 tgcgtgccag cgtccagcag cagattcggt ttgcgcccga ttttttcagc gtctttgcca
    45001 attcgtccag cgtcgcgccg gtggtaaaga catcgtcgat taacagaata ttacagtttt
    45061 ccggtatcgg tgtgcggatt tcaaaggcgt ttttgatgtt tcgccgccgt tcgccgcctt
    45121 tgagcgtgct ttgcggcggg cggtggtgtc ggaaaacggt gtgtcggggc agtatctgcc
    45181 agccgtagcg ttgtgccaac aacccgacga tgctttcact ttggttgaac ccgcgttgca
    45241 gcagccgctc cctgcttagc ggaacgggca ggacgaaatc gaagcattcg tctgcaagcc
    45301 ggtcgggcgg attctgcatc atcaggtctg ccagcggctg caccatgctc aaatcagcca
    45361 agtgcttcag cgcgtgtatc atattgctga cgggcggttc gtaatgcagc gaagcccaca
    45421 tccggtcgaa tgcgggcggt tttttctgac agccgccgca caccgcgccg ccttggatgt
    45481 gtctgaaaca cagggggcag ctgtttgccg cgtcggtgcg gtatgccgcc aaatccgccg
    45541 cgcagccggc gcagatgccg tctgaaacgc cggacgaacc gtggcataat acgcaacgcc
    45601 tgatagtggg cgcgtctgcg atgcgccgcc aacgagagag aaaatccatg cctgatgccg
    45661 tcaaaaaagt ttacctgata cacggttggg gggcgaaccg ccacatgttc gacgatttga
    45721 tgccgcgcct gcctgcaacg tggccggtgt ccgccgtcga tttgcccgga cacggcgacg
    45781 cgcccttcgc gcaacccttc gatattgagg cagccgccga cgctgttgcc gcacaaatcg
    45841 atacgcccgc cgacattctc ggctggtcgc tcggcggatt ggtcgcgctg tatctggcgg
    45901 cgcgccatcc cgacaaagtc cgttcgctct gcctgacggc gagtttcgca cggctgacgg
    45961 ctgccgaaga ttatcccgaa gggcttgccg cgcctgcact gggcaaaatg gtcggcgcgt
    46021 tccgttcgga ttatgccaaa catatcaaac agtttctaca actccagctt ctgcacacgc
    46081 ctgatgcgga cggaatcata ggcagaatcc tgcccgattt ggcacggtgc ggcacgccct
    46141 ccgccctgca ggaggctttg gacgcggcgg aaagggcgga tgcgcggcat ttgttggaca
    46201 agatagatgt tccggtactg ctggtgttcg gcggcaaaga cgcgattacg ccgccgcgta
    46261 tgggcgagta tctgcaccgg catttgaaag gcagcaggct ggttgtgatg gaaaaggcgg
    46321 cacacgcgcc gtttttgagc catgcggaag cgtttgccgc gctgtaccgc gactttgttg
    46381 aaggggtttg acatgaatcc gcaggacaaa tgctggcagg ttcaccgcca tctcgccgaa
    46441 tatgccgacc aacgcctgac actcgtccgc aacgcgccca agtatatcct gcttgccggt
    46501 gcggatgcgg acatcagccg cagcctgctg gcgaaacgct atccgcaggc ggtatttgaa
    46561 gaatacgatt cccgtgcgga ctttttggcg gctgccgctg ccgcccgcaa aggcggtttt
    46621 tggcaaaggt ttacgggtaa gggcgtggtg caacactgcc aatccccgat cgcgccgctg
    46681 cccgaagcgt gtgctgatat gttgtggtcg aatctcggac tgttggcggc ggaacaaatc
    46741 cttcctgtgc tgcacaactg ggcgtgcgcc ttgaagacgg acgggctgct gttttttacc
    46801 tgcttcgggc gcgacacttt taccgaactg aaatgccgtc tgaaagaaaa cggcattgaa
    46861 agccgcagcg tgatgtttcc cgatatgcac gacttgggcg atatgcttgc tgaaaacggc
    46921 ttttacgacc ccgttaccga tacggcgaag ctggtgttgg attacaaaaa ggcggaaacg
    46981 ttttgggcgg atatggacac gctgggcatc tggcgggcga tggcgtggaa cgatgaaaat
    47041 gccgcgcgtt cgtgtgtcgg gacaatattt gaacgggaag gcggtttgag tattacgctg
    47101 gaaacagtgt acggacacgc cgttaaaaaa ctgatgctgc cgcaagggga gaacgtggtg
    47161 cagttttttc cgaagagatg atgtgcagat gccgtctgaa gccgtttcca ggtttcagac
    47221 ggcatttgtc tgtgaaaacc gacagaaata aaggaaatac cgatgtatag tg
//
LOCUS       DAXIDM010000003        41862 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000003 DAXIDM010000000
VERSION     DAXIDM010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 41862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41862
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.003"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(697..1776)
                     /gene="apbC"
                     /locus_tag="ACFOAE_000101"
     CDS             complement(697..1776)
                     /gene="apbC"
                     /locus_tag="ACFOAE_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HFC6883681.1"
                     /translation="MNIQNIRTLLDTVAVPNTARTLGGEKAVRSVEQHSDGIHIALHF
                     GFPVAHIASETADRIQEILMPLTGDTHIHLSMNTEIGTHKVQPGVTTIKGVKNIIAVA
                     SGKGGVGKSTTTANLAAAMARMGARVGVLDADLYGPSQPTMLGVDDRKPDQKNQKLIP
                     VESSNGIQVMSIGFLVDTDQAVVWRGPMVSQALQQLMFQSEWDEVDYLFIDLPPGTGD
                     IQLTLSQRIPVTGSVIVTTPQDIALIDARKAVDMFRKVNIPILGVLENMSVHICTNCG
                     HSEALFGTDGGKDLAARLNLPLLGQLPLSLPVREAMDGGTPAQLFDEHPAIAKIYTDA
                     AFQIALSIADKGKDFSSRFPKIVVE"
     gene            1987..2062
                     /locus_tag="ACFOAE_000102"
     tRNA            1987..2062
                     /locus_tag="ACFOAE_000102"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2020..2022,aa:Lys,seq:ttt)
     gene            2141..2650
                     /locus_tag="ACFOAE_000103"
     CDS             2141..2650
                     /locus_tag="ACFOAE_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HFC6883682.1"
                     /translation="MKKKLLSGIKFAVQTALVFLLVSLFLDWVRKPEEPAGAAGRPLT
                     LLSGQRLTLGQFSRDRTVLVYFWGSWCGVCRYQSPIIDDLAADGVPVVGVAVRSGSSA
                     EVAAYMAKRGLGFPTVNDEDGGLARSWRIVATPAVVLVKNGKMVHYTTGISSYWGLRA
                     RIFQADVFG"
     gene            2993..3433
                     /gene="nadR"
                     /locus_tag="ACFOAE_000104"
     CDS             2993..3433
                     /gene="nadR"
                     /locus_tag="ACFOAE_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family adhesin repressor NadR"
                     /protein_id="HFC6883683.1"
                     /translation="MPTQSKHASINISLIQAREALMTQFRPILNQANITDQQWRIIRL
                     LAENGTLDFQDLANQACILRPSLTGILTRLEKAGLVVRLKPSNDQRRVFLKLTAEGEK
                     LYEEIGEEVDERYDAIEEVLGREKMLLLKDLLAELAKIEDALNS"
     gene            3548..4048
                     /gene="hpaC"
                     /locus_tag="ACFOAE_000105"
     CDS             3548..4048
                     /gene="hpaC"
                     /locus_tag="ACFOAE_000105"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0042537 - benzene-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     reductase component"
                     /protein_id="HFC6883684.1"
                     /translation="MADLQKTFQTSFRDAMASCAAGVHVITTDGAAGRYGITMTAVTP
                     VTDEPPTVMLCINRSARIIPILSENGSLCINTLADEHQDVAEHFAGLTGLSPEERFAY
                     HIWHRGKTGQLEIEGALAHLHGHIVGKHEIGTHFVFYVRLDEIKNCGCKRPALLYFRR
                     QFRFLD"
     gene            4064..4759
                     /gene="murU"
                     /locus_tag="ACFOAE_000106"
     CDS             4064..4759
                     /gene="murU"
                     /locus_tag="ACFOAE_000106"
                     /EC_number="2.7.7.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramate alpha-1-phosphate
                     uridylyltransferase MurU"
                     /protein_id="HFC6883685.1"
                     /translation="MKAMILAAGRGERMRPLTDTTPKPLLDVAGKPLIGWHLCRLKQA
                     GFTEIVINHAWLGRQIEDALGDGSAYGVNIAYSPEPAGGLETAGGIAQALPLLGDAPF
                     LVVNGDVLTDIDFTAAFQAASSLPEHISAHLWLVENPPHNPDGDFSLLPDGSVRPEVN
                     GGNGLTFSGVGIYRPEMFDGIEAGSVAKLAPVLRGEMRQNRVSGQKHTGLWLDVGTVC
                     RLKEAQALAGAWK"
     gene            complement(4990..5421)
                     /locus_tag="ACFOAE_000107"
     CDS             complement(4990..5421)
                     /locus_tag="ACFOAE_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HFC6883686.1"
                     /translation="MGSNAWLFWALASAGFASLTAIFAKMGLQGIDSDFATFIRTLVI
                     LAALVLFLTYTGKWQGVNGFTGKNWTFLILSGLATGASWLAYFKALQLGNASQVAPID
                     KFSLVLVALMAVVFLDERPNTQEWIGLGLVTAGVLVLALKR"
     gene            5596..7272
                     /locus_tag="ACFOAE_000108"
     CDS             5596..7272
                     /locus_tag="ACFOAE_000108"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFC6883687.1"
                     /translation="MSFKTDAEIAQSSTMRPIGEIAAKLGLNADNIEPYGHYKAKINP
                     AEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDSVIALREPSLGPV
                     FGVKGGAAGGGYAQVLPMEDINLHFTGDFHAIGAANNLLAAMLDNHIYQGNELDIDPK
                     RVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDISDLKE
                     RLGNILVAYAKDGSPVYAKDLKAHGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANI
                     AHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLAGLKPDAAVVVATVRA
                     LKYNGGVERANLGEENLDALEKGLPNLLKHISNLKNVFGLPVVVAINRFVSDSDAELA
                     MIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKI
                     RVIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEGF
                     RITVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDEHGVIHGLF"
     gene            7386..8477
                     /gene="ychF"
                     /locus_tag="ACFOAE_000109"
     CDS             7386..8477
                     /gene="ychF"
                     /locus_tag="ACFOAE_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002642527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFC6883688.1"
                     /translation="MSLKCGIVGLPNVGKSTLFNALTQSGIEAANYPFCTIEPNVGIV
                     EVPDPRMAELAKIVNPQKMQPAIVEFVDIAGLVAGASKGEGLGNQFLANIRETDAIVN
                     VVRCFDDDNIVHVAGKVDPIADIETIGTELALADLASVEKAIVREEKRARSGDKDAQK
                     LVDLCKKLLPHLDEGKPVRSFGLDAEELAMLKPLFLLTAKPAMYVGNVSEDGFENNPH
                     LDRLKELAAKENAPVVAVCAAMESEIAELEEDEKAEFLAEMGLEEPGLNRLIRAGYDL
                     LGLQTYFTAGVKEVRAWTIHKGDTAPQAAGVIHTDFERGFIRAQVISYEDFIALGGEA
                     KAKEAGKMRVEGKEYVVQDGDVMHFLFNV"
     gene            8525..9994
                     /locus_tag="ACFOAE_000110"
     CDS             8525..9994
                     /locus_tag="ACFOAE_000110"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883689.1"
                     /translation="MTGKNYLKRMDFGNEAADDVDDEELKSYFVMQEGFENFLKENKR
                     LQVIKAKKGMGKSALIKWIGLEVSEKYQNALVIKIRGSELSRENFKLTKKLTEPNDYI
                     SDWIIRLCAVVNRELAKKINFAYRDDEISLVESTEVQGFKERNLISCLLERFKNILGK
                     FQPEPTTNINHPEILKRIESLDYSKIWILIDDLDATFQNTNKEKVNLGSFFSACRYMI
                     QDLKGVNFRITLRSDVWPVIRRHDEAMDKIEQYISEIEWTEEDFKQILCRRIQKEFPD
                     DSINLTDDELLKKIFKPTVFWNEKQVPTYQVLYILAYNRPRWGVQLCKLAQADALRKS
                     MLHIEKLNIDARWGEYGLKRIADLVVEHKHQCIQIEDLINYFRGLERRFSQPDLLELL
                     RKKVLGSMTIQIDGQTIQKSKPEAIADFLFRIGFIVARAEEEHYGYHHYSYSELPDLF
                     SGKNSDGFSLMWEIHPCYREALNIKKLNAEQRNQKNLSH"
     gene            10017..11315
                     /gene="tyrS"
                     /locus_tag="ACFOAE_000111"
     CDS             10017..11315
                     /gene="tyrS"
                     /locus_tag="ACFOAE_000111"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFC6883690.1"
                     /translation="MTSVIQDLKARGLIAQTTDIEALDALLNEQKIALYCGFDPTADS
                     LHIGHLLPVLALRRFQQAGHTPIALVGGATGMIGDPSFKAAERSLNSAETVAGWVESI
                     RNQLTPFLSFEGGNAAIMANNADWFGSMNCLDFLRDIGKHFSVNAMLNKESVKQRIDR
                     DGAGISFTEFAYSLLQGYDFAELNKRHGAVLEIGGSDQWGNITAGIDLTRRLNQKQVF
                     GLTLPLVTKSDGTKFGKTEGGAVWLNAKKTSPYQFYQFWLKVADADVYKFLKYFTFLS
                     IEEIDAIEAKDKASGTKPEAQRILAEEMTRLIHGEAALQAAQRISESLFAEDQSSLTE
                     SDFEQLALDGLPAFEVSDGINVVEALVKTGLASSNKEARGFVNSKAVLLNGKPAEANN
                     PNHAAERPDDACLLNGEHKRFGKYTILRRGKRNHALLVWK"
     gene            11842..12762
                     /gene="ribF"
                     /locus_tag="ACFOAE_000112"
     CDS             11842..12762
                     /gene="ribF"
                     /locus_tag="ACFOAE_000112"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HFC6883691.1"
                     /translation="MRIRLGRHNAPDFPHGAAVTIGNFDGVHLGHKHILQKLRLEADT
                     RGLPVVTVVFEPQPKEFFALRTGRMPPCRISPLRTKLELLEGTGCVDAVWVLRFDQNF
                     SEISAQAFIDRLLRQTLNTRYLLVGDDFRFGAGREGCFELLAQQPDMQTERTPSVIVE
                     DIRTSSTAVRQALSDGNLAYAKKLLGHDYVLSGRVVHGRKLGRTLNAPTANIRLPGHR
                     YALGGVFVVEADGAFGTRRGVASFGFNPTVDSGCSQKLEVHLFDFQGDLYGQRLNVRF
                     LHKLRDEEKFDGMEELKRQIEADMEAAKCW"
     gene            12903..15692
                     /gene="ileS"
                     /locus_tag="ACFOAE_000113"
     CDS             12903..15692
                     /gene="ileS"
                     /locus_tag="ACFOAE_000113"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFC6883692.1"
                     /translation="MTDYSKTVNLLESPFPMRGNLAKREPAWLKSWYEQKRYQKLREI
                     AKGRPKFILHDGPPYANGDIHIGHAVNKILKDIIIRSKTQAGFDAPYVPGWDCHGLPI
                     EVMVEKLHGKDMPKARFRELCREYAAEQVARQKKDFIRLGVLGDWDKPYLTMDFKTEA
                     DTVRMLGEIYKSGYLYRGAKPVQFCLDCGSSLAEAEVEYKDKVSPAIDVAYPFKDTAA
                     LAAAFGLAGIEGKAFAVIWTTTPWTLPASQAVSAGADVVYQLIDTPKGKLVLAKDLAE
                     DALKRYGFSDGIAILAETTGDKLENLHMNHPFLERDIPMLNGDHVTTDAGTGLVHTAP
                     AHGLEDYTVCNKYGIELYNPVNAEGKYISETPRVAGMRVWEANPIILQWLEETGNLLA
                     SSKIEHSYAHCWRHKTPLIYRATGQWFVGMDKAGADGKTLRDKAIKAVDDTEFFPSWG
                     RARLEAMIEGRPDWVVSRQRYWGTPMTFFVHKETGELHPNSAELLEKVALKIEEKGIE
                     AWFSLDKSELLSAEDCENYDKLSDTMDVWFDSGSTHYSVVKQREELEWPADLYLEGSD
                     QHRGWFQSSMLTGCASSMGRAPYKQLLTHGFVVDQNGRKMSKSIRNVVAPQEVYNEFG
                     ADILRLWAASTDYSGELSISKEILKRVTESYRRIRNTLSFLFANLSDFNPIEDAVQQA
                     DMVEIDRYALVLARQLQERLAGDYYPRYTFHFAVKDIVSFCSEDLGAFYLDILKDRLY
                     TTKADSRARRSAQTALYHITRSLVLLIAPILCFTGEEAWDIIGGGEEDSVLFHTWHEF
                     PTINEKAEAELVKKWTAIREAREAVTAAIELLRADKTVGSSLQAEAEITAPEEMAGYL
                     NALGEELRFALLVSKAEVKVGDELAVTAKASDGEKCERCWHYTHDVGAVAGYETVCKR
                     CAENVGGEGETRHYA"
     gene            16387..16914
                     /gene="lspA"
                     /locus_tag="ACFOAE_000114"
     CDS             16387..16914
                     /gene="lspA"
                     /locus_tag="ACFOAE_000114"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFC6883693.1"
                     /translation="MVLFYRLLKNMSSSVSSKTRYWVLALAAIVLDQWSKWAVLSSFQ
                     YRERVNVIPSFFDLTLVYNPGAAFSFLADQGGWQKYFFLVLAVAVSAYLVRAILRDEF
                     ATLGKTGAAMIIGGALGNVIDRLIHGHVVDFLLFYWQNWFYPAFNIADSFICVGAVLA
                     VLDNIVHRKTQEEKY"
     gene            16943..17911
                     /gene="ispH"
                     /locus_tag="ACFOAE_000115"
                     /gene_synonym="lytB"
     CDS             16943..17911
                     /gene="ispH"
                     /locus_tag="ACFOAE_000115"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA];
                     GO_process: GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HFC6883694.1"
                     /translation="MNEKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVH
                     NKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLV
                     TKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPD
                     KLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIV
                     IVVGSPNSSNSNRLREVAASRGIDAYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLV
                     REVLATIRGWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR"
     gene            complement(17998..18657)
                     /locus_tag="ACFOAE_000116"
     CDS             complement(17998..18657)
                     /locus_tag="ACFOAE_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC6883695.1"
                     /translation="MTPPKLIIFDWDGTLADTTQPIIDTMRRSFAECGFPPPEAERVR
                     SLIGYSLPEIIRTLLEMPSETAIADITRTYSAHYLNPNNRNMTLFPDALPCLDKLKAQ
                     GYWLAVATGKGRAGLDNAISQTATGGYWLATACAGEYPSKPSPEMVFGICGELGLDPK
                     EALVVGDTAHDLHMAANAGAAAVGVTTGAHSREQLRTAPHLAVLDGLSELPGFLARHY
                     A"
     gene            18817..20973
                     /locus_tag="ACFOAE_000117"
     CDS             18817..20973
                     /locus_tag="ACFOAE_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HFC6883696.1"
                     /translation="MSVFRINMTAATVLAALSSSVFAAQTADLETVHIKGQRSYNAIA
                     TEKNGDYSSFAVTVGTKIPASLREIPQSVSIITNQQVKDRNVDTFDQLARKTPGLRVL
                     SNDDGRSSVYARGYEYSEYNIDGLPAQMQSINGTLPNLFAFDRVEVMRGPSGLFDSSG
                     EMGGIVNLVRKRPTKAFQGHMAAGFGTHKQYKAEADVSGSLNSDGSVRGRVMAQTVGA
                     SPRPAEKNNRHETFYAAADWDINPDTVLGAGYLYQQRHLAPYNGLPADANNKLPSLPQ
                     HVFVGADWNKFKMHSHDVFADLKHYFGNGGYGKVGMRYSDRDADSNYAFAGSKLGMKT
                     PAGRPGCNTADDKACAVGLGTEIKQKALAFDASYSRPFRLGNTANEFVIGADYNRFRS
                     TNEQGRTTLYARGGLALNEFRSIPQVDLIANARKGVRGYSHTVATENLDEFGIYGKST
                     FHPADGLSLIGGGRLGHYKIESGEGDELHKASKTKFTGYAGAVYDLNDNNSLYASFSQ
                     LYTPQTSLGTDGKLLKPRQGNQFEVGYKGSYMDDRLNARVSFYRMKDKNAAAPLNPNN
                     KKTRYAALGKRVMEGVETEISGAVTPKWQIHAGYSYLHSQIKTASNSRDDGIFLLMPK
                     HSANLWTTYQVTPELTIGGGVNAMSGITSSAGMHAGGYATFDAMAAYRFTPKLKLQIN
                     ADNIFNRHYYARVGGANTFNIPGSERSLTANLRYSF"
     gene            21043..21975
                     /locus_tag="ACFOAE_000118"
     CDS             21043..21975
                     /locus_tag="ACFOAE_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFC6883697.1"
                     /translation="MLSQLEYGIAKENRPNRQADRFAGSVLPLAASLTHKPNIMKPIP
                     TDTFQPAILPQAFETEIKSTCTGRIYRIQTATLGEMPSEGYPVLFVLDGEAFFPALFN
                     IMQSLMPNPVTRSNAPCLIVGIGYTTGSVRDLAQRAADYTPPLGDNATADERQQFGQA
                     DRFSAFIDSELTAFLESRYTLNRNETAVFGHSFGALFGLYSLLSHRRFRRHWLVSPSI
                     WWHNRRILDFMPSENRLNGIDVCLNIGALERGSGCKRREKRDMAGLSERMAAELDRHG
                     AAVFFREYPNADHGNVSFYSLTDCVEYLRKAWQR"
     gene            complement(22112..22366)
                     /locus_tag="ACFOAE_000119"
                     /pseudo
     CDS             complement(22112..22366)
                     /locus_tag="ACFOAE_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742773.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22409..25843)
                     /gene="dnaE"
                     /locus_tag="ACFOAE_000120"
     CDS             complement(22409..25843)
                     /gene="dnaE"
                     /locus_tag="ACFOAE_000120"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFC6883698.1"
                     /translation="MTEPTYIPLRLHTEFSITDGMVRIKKLIAKAQEYGLPALGISDL
                     MNEFGLVKFYKACRGAGIKPIGAADVWIGNPNAPDKPFRAMLIIRNDAGYLRLSELLT
                     EAYVGKDRNVHHAELNPEWLENGDNSGLICLSGAHYGEVGMNLLNGNEDAARAAALKY
                     AAWFPDAFYLELQRLPERPEWEACVSGSVKLAEELGLPVVATHPTQFMSRDDFNAHEA
                     RVCIAGGWVLTDKKRPRDFTPSQFFIPPETMAERFADLPEALENTVEIAKRCNLHITL
                     GKNFLPLFPTPDGLSLDDYLIKLSNEGLQERMVQLYPDEAERAEKMPEYQERLDFELN
                     IIIQMKFPGYFLIVQDFINWAKTHGCPVGPGRGSGAGSLVAYSLKITDLDPLKYALLF
                     ERFLNPERVSMPDFDVDFCQSNRGRVIEYVREKYGAEAVSQIVTFGTMSSKAVIRDVG
                     RVLELPFTLCDKLSKLIPLEANKPLGLDDAMKAEPQIQELIEAEEADELITLAKKLED
                     LTRGLGMHAGGVLIAPGKISDYSPVYQADESASPVSMYDKGDVEDVGLVKFDFLGLRN
                     LTIIEMAQDNIKNTTGDIIDVGKIPLDDQAAYQIFRDANTTAVFQFESTGMKKMLKTA
                     HTTKFEELIAFVSLYRPGPMDNIPDFVARMKGQEFQYIHPLLEGILAPTYGIMVYQEQ
                     VMQAAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKQGISREKSDEIFNY
                     MEKFAGYGFNKSHAAAYALISYQTAWLKAHYPAEFMAATMSSELDNTDQLKHFYDDCR
                     ANGIEFLPPDINESDYRFTPYPDMKIRYALGAIKGTGEAAVESITSARQSGGKFTGLL
                     DFCERVGKEHMNRRTLEALIRGGAFDSIEPNRAMLLANIDLAMNNADQKAANANQGGL
                     FDMMEDAIEPVRLIDAPMWSESEKLAEEKTVIGFYLSGHPFGPYAQEVRQIAPQKLSK
                     LKPQDSVRLAGFVTAVRTMMGKRGKIAFVSLEDLSGQIEIMVSGQTLENCADCLKADQ
                     VLIIESKVSRDDYGGGDGLRIMANQVMTLQTARERYARSLSLALAPHHDIGGLVRLLS
                     SHQLPDTPRIPLQLSYANEKASGRLQVPPKWTVTPSSALFGELETLLGSRSVRVNW"
     gene            26207..26608
                     /locus_tag="ACFOAE_000121"
     CDS             26207..26608
                     /locus_tag="ACFOAE_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFC6883699.1"
                     /translation="MQSAVGQDFFDRIAAYGVSDGIFTEQAVRIHRWFCGNFGYGGGR
                     CYNNGLFLQGDIMEAIVYLEDNEYIALCDLLKLVGLAESGGQAKAFIAEGLVLRNGET
                     ETRKTAKIRGGEVIEFDGARLEIADGYDPEA"
     gene            26586..26789
                     /locus_tag="ACFOAE_000122"
     CDS             26586..26789
                     /locus_tag="ACFOAE_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase-like domain-containing protein"
                     /protein_id="HFC6883700.1"
                     /translation="MDMTLKHKAEALLGEPLLDEPVRPESWECCGSDCGEACIQTIYW
                     ADKARYDAQRRKLKEAGWSDDAV"
     gene            27235..28071
                     /locus_tag="ACFOAE_000123"
     CDS             27235..28071
                     /locus_tag="ACFOAE_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFC6883701.1"
                     /translation="MIDLHCHSTVSDGMLSPAEVVRLAHQNGCTLLALTDHDHTGGIA
                     EARAEADRLDLRLINGVEISVTWRGRTIHVVGLDFDERDENLQNLLAQVRQGRLKRLE
                     AIAAKLEKKGIGGAYDGALALAANKEMVSRTHVAEFLIRVGHVKNKQQAFTKYLGDGK
                     SCAVRHEWATLEDCVSAVNGAGGLAVIAHPMRYDLSATAKRNLFEEFKNLGGAGIEVH
                     SGNCCKNDRLNYALLAERFGMLASAGSDFHRLNDFSGGILGACPELPENCRPVWAHFS
                     RY"
     gene            complement(28123..29415)
                     /locus_tag="ACFOAE_000124"
     CDS             complement(28123..29415)
                     /locus_tag="ACFOAE_000124"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HFC6883702.1"
                     /translation="MQFSAFGEKFTQHSGILQLMDDLGDALKSDKPVNMLGGGNPARI
                     AEVNAVFADVFSKLAAEHAVENIGNYSNPQGDAALIDALTAFLNREYGWNLTADNIAL
                     TNGSQNAFFYLFNLFGGKFNLSDGTSAEKAILLPLAPEYIGYADVHVEGQHFVSVKPK
                     IENVEHEGEAGFFKYRVDFDALENLPELKAGKIGAICCSRPTNPTGNVLTDSEMARLD
                     ALAQEHGIPLIIDNAYGMPFPNIIYSDVTLNWHENIILCFSLSKVGLPGVRTGIIVAA
                     PEVVKAVSSLNAIVNLAPTRFGAAIAAPLLESGEMKRLADQVIRPFYRNQAQTAVSLL
                     KRELGAYPMKIHKPEGAIFLWLWFENLPVSSQTLYEMLKAEGTLIIPGEHFFVGIDTR
                     DYPHAGECIRMSIAQDAQTLEKGIAAIGKTVRKLYDNV"
     gene            complement(29471..31381)
                     /gene="pglD"
                     /locus_tag="ACFOAE_000125"
     CDS             complement(29471..31381)
                     /gene="pglD"
                     /locus_tag="ACFOAE_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent dehydratase PglD"
                     /protein_id="HFC6883703.1"
                     /translation="MTLETLLALPRNIKKICFLIHDFLMIFIAFWFTQSLKADYSNEW
                     FDPTNWQSFLLTAPLTIGLFVRMGLYRAVTRFISFRILSTALAGSLASAVLFFLNTLI
                     FEERLRLALPIVYFLLLFVSVTGSRMVLRGLLSEHPKKQMIPVIIYGAGQAGRQLLEA
                     VKQMREYSAAAFVDDDPKLWHTVIYDLAVYQPDAIAFLIERYGVEKILLAIPGATQEQ
                     RRRIINKLEAYPCEVLTIPGMKDLMDGKISIGTLKKISVSDLLGRDSVAPDNRLMSAD
                     IEGKTVMVTGAGGSIGSELCRQIIRRRPEKLLLFELSEFALYAVEKELRETCIQKRLD
                     TEILPFLGSVQNRTLLEHVMTAFSVATVYHAAAYKHVPMVEFNTVEGIRNNIFGTLEC
                     ALAATTSGVETFVLISTDKAVRPTNTMGASKRMAELCLQALAAEPGQKTRFSMVRFGN
                     VLGSSGSVVPLFEKQIAEGGPLTLTHPEITRYFMTIPEAAQLVIQAGAMGTGGDVFVL
                     DMGESVKIIDLARQMITLSGLKPNTPEQPDGDIEILITGLRPGEKLYEELLIGDNVRK
                     TGHPRIMTANETMLPWHELSALLDRIRAACDRYDQQAIRTLLINAPTGFAPSDGICDL
                     LWVRETHRKNAV"
     gene            complement(31429..32604)
                     /locus_tag="ACFOAE_000126"
     CDS             complement(31429..32604)
                     /locus_tag="ACFOAE_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HFC6883704.1"
                     /translation="MLNTSLSPWPCFTQEEADAVSKVLLSNKVNYWTGSECREFEKEF
                     AAFSGTRYAVALSNGTLALDVALKAIGIGVGDDVIVTSRTFLASASCIVNAGANPVFA
                     DVDLNSQNISAETVKAVLTPNTKAVIVVHLAGMPAEMDGIMALAKEHNLWVIEDCAQA
                     HGAKYKGKSVGSIGHVGAWSFCQDKIMTTGGEGGMVTTNDKTLWEKMWSYKDHGKSYD
                     AVYHREHAPGFRWLHESFGTNWRMMEMQAAIGRIQLKRLPEWTACRQAHAAKLAESLG
                     KFKSIRLVEVADYIGHAQYKFYAFVKPEHLKDGWTRDRIVNELNARKVPCYQGSCSEV
                     YLEKSFDNTPWRPKERLKNAVELGDTSLMFLVHPTLTDGEIAFCKEHIEAVLTEATR"
     gene            32645..32809
                     /locus_tag="ACFOAE_000127"
     CDS             32645..32809
                     /locus_tag="ACFOAE_000127"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883705.1"
                     /translation="MPSEGGVFRRIGRTPQVLSKSVCTGVYSGLNLNQYGVASPCRTI
                     CTVCGFVALS"
     gene            complement(32832..33026)
                     /locus_tag="ACFOAE_000128"
     CDS             complement(32832..33026)
                     /locus_tag="ACFOAE_000128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883706.1"
                     /translation="MTKYYSWGVNGFPPYVFDTIWKRWKLNGRGGGYRVRHPGRHDRR
                     GQSGKAATAQKPQDRDGISD"
     gene            complement(33074..33760)
                     /locus_tag="ACFOAE_000129"
     CDS             complement(33074..33760)
                     /locus_tag="ACFOAE_000129"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC6883707.1"
                     /translation="MKTINPETTVIVFDLDDTLYSEYEYKLSGIRSVIDTVAALYPDW
                     NSDNLWRNIDPDGKDWLDKLCRHCGFNESEKQVLLWQYRLHRPTLTPYAPPDFLSELT
                     APFAARALITDGRSLTQRLKLEALGLSSLFDDILISEACSSEKPDGKRFRHLQDKYAD
                     KAGCFIYIGDNISKDFIAPNTLGWITIGLLPSGQNIHRHQPESFNTEYHPDFWVNSLQ
                     DLVPIIDSNT"
     gene            complement(33747..34748)
                     /locus_tag="ACFOAE_000130"
     CDS             complement(33747..34748)
                     /locus_tag="ACFOAE_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HFC6883708.1"
                     /translation="MPYFTGNQTNEKNNILILSAGRRVELVQDFQTEAARFSDGISVF
                     ATDLNPRMSSACHVSDGSFEVPPISTDSYIDSIFNLAVRENIGLIIPTIDTELQKLAD
                     ERERFEAASVHIVVSDSDFIAQCRDKRKTATLFARYGIRSPEIYDRKKLVFPCFAKPY
                     DGSRAIGAKRIDTPADLTPEVLADTKLMFCQFIDIENKFSEFTVDMYYDRQCRLKCAI
                     PRKRLEVRSGEISKGVTCKNSLYQTLLEKMAVLQGARGCITAQFFYNEETGEFYGVEI
                     NPRFGGGFPLTYAAGGNYPSRLMREYLGDEEIPFSDDWENNLIMLRYDAKVLVHEND"
     gene            complement(34797..35324)
                     /locus_tag="ACFOAE_000131"
                     /pseudo
     CDS             complement(34797..35324)
                     /locus_tag="ACFOAE_000131"
                     /inference="COORDINATES: protein motif:HMM:NF014453.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
     gene            complement(35317..36483)
                     /gene="pglH"
                     /locus_tag="ACFOAE_000132"
     CDS             complement(35317..36483)
                     /gene="pglH"
                     /locus_tag="ACFOAE_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminyl-a1,3-N,
                     N'-diacetylbacillosaminyl-a1-diphospho-di-trans,
                     octa-cis-undecaprenol synthase PglH"
                     /protein_id="HFC6883709.1"
                     /translation="MNITIVAPYCSLPSEPYFNRFWYLAERLSQSHDVLLITSRFRHY
                     DKSFRRHEDAAATSNGRLRVKLLDEPGYRKNVSLARVASHRVFVRNLARWLHSPQAAE
                     QDIVYSAYPLMATNLLLGKHKARLGYKLIVDVQDVWPESFSSVVPFLKKVPHKLLPFA
                     SRANRAYRCADALVAVSQTYLDRAKEANPNVPGEAVYIGTDFAAIAPPPRFRSKTTRL
                     FYLGTLSYSYDVETVCKGVRKLLDDGENVELHIMGGGPDLEKLKQYENRAIKFYGYLP
                     YSEMMSIAKGCDIAVNAIHSHAMQSVTNKLSDYMALQKPILNSQTNAEVLSLLNLLPH
                     ENYRSGDVDSFVQAAKDILKRKNDPVQSDEIVRRFRRDISYRKIVNLIERLANE"
     gene            complement(36503..37576)
                     /locus_tag="ACFOAE_000133"
     CDS             complement(36503..37576)
                     /locus_tag="ACFOAE_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC6883710.1"
                     /translation="MKIILTTSMSGLGGTETATVRLGRLLKRRGHDIILASSDGPFVG
                     EAQASGIRWQPVDFYRGGLFGYLKGMIAYARMLRREQPDIIDCQMARVVPACAIAAKI
                     VSPKTKIIYHSHGLDAATYPKIAKLFDKLGVYIIGNCKHEREKLIRHGFPADRIVYAY
                     NALPPPPEFPFWKTVKGCVMLGTLSRLDTVRAVHLMLDIFKKMVDRDMPVRLNVAGIG
                     EEMDNLKAQAERLGIDGKVTFLGGIRDLTAYFKDVDILVNTPHCIGDHGAGVGNNILE
                     AGLYDTPVVTYDMAGISEMVVNGETGYCIPFGDEEAFIAAVDTLVRQPELREAMGKRL
                     HAHVAALCSDDEIYRTTMAAYTM"
     gene            complement(37573..38994)
                     /locus_tag="ACFOAE_000134"
     CDS             complement(37573..38994)
                     /locus_tag="ACFOAE_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HFC6883711.1"
                     /translation="MDTKEILGYAAGSIGSAVLAVIILPLLSWYFPADDIGRIVLMQT
                     AAGLTVSVLCLGLDQAYVREYYAAADKDTLFKTLFLPPLLSAAAIAALLLSRPSLPSE
                     ILFSLDDAAAGIGLVLFELSFLPIRFLLLVLRMEGRALAFSSAQLVSKLAILLLLPLT
                     VGLLHFPANTAVLTAVYALANLAAAAFLLFQNRCRLKAVRRAPFSSAVLHRGLRYGIP
                     IALSSIAYWGLASADRLFLKKYAGLEQLGVYSMGISFGGAALLFQSIFSTVWTPYIFR
                     AIEENAPPARLSATAESAAALLASALCLTGIFSPLASLLLPENYAAVRFIVVSCMLPP
                     LFCTLAEISGIGLNVVRKTRPIALATLGALAANLLLLGLAVPSGGARGAAVACAASFW
                     LFFVFKTESSCRLWQPLKRLPLYTHTLLCLTSSAAYTCFGTPANYPLFAGVWAVYLAG
                     CILRHRKDLHKLFHYLKKQGFPL"
     gene            complement(39189..40298)
                     /gene="ribD"
                     /locus_tag="ACFOAE_000135"
     CDS             complement(39189..40298)
                     /gene="ribD"
                     /locus_tag="ACFOAE_000135"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HFC6883712.1"
                     /translation="MFSDTDISMMETALRLAALGRFSTSPNPRVGCVIAHGSQIVGQG
                     FHVKAGEPHAEVHALRQAGEMAQGATAFVTLEPCSHYGRTPPCAEALLRSGVTRVVAA
                     MRDPNPLVAGKGLALLEAAGIKTECGLLEHQARELNRGFLSRIERRRPFVRLKCAVSL
                     DGKTALSDGSSFWITGEDARADVQVLRAESCAVLTGIGTVLADNPRLNVRAFPTLRQP
                     ARIVLDSRLRLPLDSHLLTDGQSPTYIATLERDEDKLRPYRKHAHVRILMPSETAGGK
                     IDLNHLMRLLADEGFGEIMVEAGSELTSAFLAENLADEIVLYRSPKILGSGKDLFSLL
                     ENRAALSAPPLWTPVSSEILGHDIKTVFRKNGNAF"
     gene            complement(40331..40795)
                     /locus_tag="ACFOAE_000136"
     CDS             complement(40331..40795)
                     /locus_tag="ACFOAE_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFC6883713.1"
                     /translation="MKCPFCAHPDTRVADSRLMEERNAVRRRRHCPSCGKRFGTLETA
                     ELKMPAVIGPDKKRSPFNAQRLRNDLTAAARKSALTPEQIDETVRLTKHRLYTSGQRD
                     IPSAALADMVLKELLEHNTEAAVRFAALHKRFDNPADFASWLAQAVKTDRKA"
     gene            complement(40824..41666)
                     /locus_tag="ACFOAE_000137"
     CDS             complement(40824..41666)
                     /locus_tag="ACFOAE_000137"
                     /EC_number="2.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HFC6883714.1"
                     /translation="MCQLLGMNCNTPTDIMFSFEGFRRRGGITDHHADGFGIGFFEGK
                     GVRLFHDDKPSANSPVADLVRAYQIKSENVVAHIRKASQGQTSLANTHPFMREMWGGY
                     WLFAHNGHLINFFPEQGEFFHPVGTTDSERAFCHILNRLRTRFAARPDDDTLFDAIAG
                     LTHEIRKFGLFNFMLSDGIALFAHASTLLHYIVRQAPFGKARLLDDDVMVDFAEVTTP
                     SDRVAVIATLPLTRDESWSQLAVDELVMFREGNIVRHDRPENPVYMSAEEGLEIARAA
                     GVSV"
BASE COUNT         9483 a        10713 c        12065 g         9601 t
ORIGIN      
        1 ctcaaccgcc ccaatacaag cctttcggct tgttgccctc tctctagctc tctcccacag
       61 ggagagagga cggggaggct gttggggttg aggtttgctg caaggaaaac aggttgtgca
      121 ggctgctttt tatttttcag acgacctgaa acaacagctg caaatctaag ttgcctttca
      181 aatcgcctgc aaccgaaaaa tctgccgaaa cccactccct cccccgtggg ggagggccgg
      241 ggaggcggca ttttccaagt tgcggcaacc tttcccaaca actcaaccgc cccaatacaa
      301 gcctttcggc ttgttgccct ctctccagcc ctctcccacg gggagagagg acggggaggc
      361 tgttggggtt aagggttttg taaactaatc aggttgtgca ggctgctttt tgcttttcag
      421 acgacctgca tcaacggttg taaatccaat ctgtttttca aaccgcctgc aaccgcaaaa
      481 cctgccgcaa tccgctccct cccctgtggg ggagggccgg ggagagggca ttctccaagt
      541 tgcggcaatc tttcccaaca gcttaaccgc cccaatacaa gccttgcggc ttgttgccct
      601 ctctccagcc ctctcccacg gggagagagg actatgaagc ccgccggcag gcgcggggct
      661 tgggacggca ttgctgttgc ggtttcggac gcggctttat tcgacgacga ttttggggaa
      721 gcggctgctg aagtctttgc ctttgtcggc aatgctcagg gcgatttgga atgcggcatc
      781 ggtgtagatt ttggcgatgg cggggtgttc gtcgaacagt tgcgccggtg tgccgccgtc
      841 catggcttcg cgcacgggca ggcttagggg aagctgtccg agcaggggga ggttgaggcg
      901 tgcggctaaa tctttgccgc cgtccgtgcc gaacagtgct tcgctgtgtc cgcagttggt
      961 gcagatgtgg acggacatat tttccaatac gcccaaaatg ggaatgttga ctttgcggaa
     1021 catatccacg gctttgcgcg cgtctatcag ggcgatgtcc tgcggcgtgg ttacgatgac
     1081 ggaaccggtt acggggatgc gctgggacag cgtgagctgg atgtcgcccg tacccggggg
     1141 caggtcgatg aaaagatagt ccacttcgtc ccactcgctt tgaaacatca gttgctgcaa
     1201 ggcttggctg accatcggcc cgcgccagac gacggcttgg tcggtatcga cgagaaagcc
     1261 gatagacatg acctgtatgc cgtttgaaga ttcgacagga atcagttttt ggtttttctg
     1321 gtcgggtttg cggtcgtcca cacccaacat ggtcggttgg ctcgggccgt aaaggtcggc
     1381 atcgagtacg ccgacgcgcg cgcccatccg cgccatcgcg gcggcaaggt tggcagtggt
     1441 ggttgatttg cccacgccgc cttttcccga tgcgacggca atgatgtttt tcacaccttt
     1501 gatagtggta acgccgggct ggactttgtg tgtgccgatt tccgtgttca tggacagatg
     1561 gatgtgtgtg tcgcctgtca gcggcatcag gatttcctgt atgcggtcgg ctgtttctga
     1621 ggcaatgtgc gcgacaggga aaccgaaatg cagggcgata tggatgccgt ctgaatgctg
     1681 ttcgaccgaa cggacggcct tttcgccgcc gagcgtgcgt gccgtattcg gaacggcgac
     1741 ggtgtcgagg agggtgcgga tgttttgtat gttcataatg tgtgtttctg tgtgcagttt
     1801 gggaaacggg cggaaagtgt acattgattt cgggcggttt gcctttcctt gtgcgaactt
     1861 ttacacggta tgcggcggat tgtgaaaatc cgttgtcaaa atatcccgtg caaacagtgg
     1921 tctgcaatta agcctgtaaa atttgcttga cgaggcagga tggtgctgta taatgcacgg
     1981 cttatcgggt cgttagctca gccggtagag cagcggactt ttaatccgtt ggtcgagcgt
     2041 tcgaatcgct cacgacccac caaataaccg gaagccaagt tttgagactt ggctttttgt
     2101 ttgcctgccg gttgcgcggg cgtaccgttt gagggggcgt atgaaaaaga aactgctttc
     2161 gggcatcaaa tttgccgttc agacggcatt ggtgttttta ttggtgtcgc tgtttttgga
     2221 ttgggtacgc aagcccgaag agccggccgg cgcggcaggg cggcctttga ccctgctgtc
     2281 ggggcagcgg ctgactttgg gacagtttag ccgggatagg acggtgctgg tgtatttttg
     2341 gggaagctgg tgcggcgtgt gccgttatca gtcgccgata atcgatgatt tggcggcgga
     2401 cggcgttccg gtcgtcggcg tggcggtacg ttccggcagt tcggcggaag tggcggcgta
     2461 tatggcaaaa cgcggcttgg gctttccgac tgtcaacgat gaggacgggg gtttggcaag
     2521 gtcttggcgg attgtcgcaa cgcctgccgt cgttttggtc aaaaatggga aaatggttca
     2581 ctatacgacg ggaatcagca gttattgggg cttgcgcgca cgaatttttc aggcggatgt
     2641 tttcggttaa cttttgtttt tgttaaactt tacgctatgt agagagtcaa acggcatatg
     2701 ccttgcgcgg cggatgcggc ggcttttgtt ttttctggaa gaaagttctt tcgacagtaa
     2761 atgtaatact ttgttgagat tgtagggaaa atagactaag atataactat taaaatattt
     2821 ttagatagga ttatcggaat taaagtcttt tatacccagt cgtccgatgc ggtttatagc
     2881 gtattgttgc tatatgttcg ttttgttata taacggttgc atcaaaattt acgcccacag
     2941 gctttcccga cggtttgaaa gtttgatttt cgataacttg gagacttgaa caatgcctac
     3001 ccaatcaaaa catgcgtcta tcaatatcag tctgatacag gcaagggaag ccctgatgac
     3061 ccaattcagg cctattctga atcaggcgaa tattaccgat cagcaatggc ggattatccg
     3121 tcttttggcg gaaaacggca cgctggactt tcaagatttg gcgaatcagg cgtgtattct
     3181 gcgccccagc ctgaccggta tcctgacccg ccttgaaaaa gcgggtttgg ttgtccgcct
     3241 gaaaccttcc aacgaccaac gacgtgtttt tctgaagctg actgccgagg gcgagaagct
     3301 gtatgaggaa atcggcgaag aagtggacga gcgttacgac gctatcgagg aagtgctggg
     3361 ccgcgagaaa atgctgctgc ttaaagacct gttggcagaa cttgccaaaa tcgaggatgc
     3421 gttgaactcg taatacgccg taacgcgcgg aaacgtccga ccgacggctt tttgaatcaa
     3481 aactgctgca catgggggat gccttgtgtg cagcattctt atatagggga cagtttaaag
     3541 gggaaaaatg gcggatttgc agaaaacttt tcaaacttcg ttccgtgatg cgatggcatc
     3601 ttgtgcggca ggcgttcatg tcatcacgac agacggtgcg gcagggcgtt acggcattac
     3661 aatgacggcg gttacaccgg ttacggacga gccgccgacc gtgatgctgt gcatcaaccg
     3721 gagtgcgcga atcattccga tcctgtcgga aaacggcagc ctctgcatca atacgctggc
     3781 ggacgaacat caggatgttg ccgaacattt tgccgggctg accgggctgt cgcccgaaga
     3841 gcggtttgcc taccacatct ggcatcgcgg caaaacggga caacttgaaa tagagggcgc
     3901 gttggcgcac ctgcacgggc atattgtcgg caaacatgaa atcggcacgc attttgtgtt
     3961 ttacgtcagg ctcgacgaaa tcaaaaactg cgggtgcaaa cgccccgcgc tgctgtattt
     4021 cagacggcag tttagatttt tagactgata ttcggacaga tatatgaaag cgatgatact
     4081 ggcggcagga cgcggcgagc gtatgcgccc tttgaccgat accactccga agccgctgct
     4141 cgatgtggcg ggtaagcctc taatcggttg gcacctatgc cgtctgaagc aggcggggtt
     4201 taccgaaatc gtcatcaacc acgcttggct gggccggcag atagaagatg ctttgggcga
     4261 cggctcggct tatggcgtga acatcgccta ttcgcccgaa cccgcaggcg gtttggaaac
     4321 ggcaggcggc atcgcgcagg cattgccgct gttgggcgat gccccgtttt tggtcgtcaa
     4381 tggcgacgtg ctgaccgaca tcgattttac cgccgcgttt caggcggcat cgtccctgcc
     4441 ggaacatatt tccgcccatc tgtggctggt ggaaaatccg ccgcacaacc ccgacggcga
     4501 tttttccctg ctgcccgacg gcagcgtgcg gccggaagta aatggcggca acggattgac
     4561 attcagcggc gtgggtattt accgtcctga aatgtttgac ggaatcgaag cgggcagtgt
     4621 ggcgaaactc gcgcccgtat tgcgtggcga aatgcggcaa aaccgcgtga gcggtcagaa
     4681 gcatacgggc ttgtggctgg atgtcggcac ggtatgccgt ctgaaagagg ctcaagccct
     4741 tgcaggggct tggaagtgaa ataaaacggt ggcttgccga gccggctgcc gaacggttcc
     4801 gaccggatgt ccagcatatt ttcgtggagg cgtgaaaata gggcgttcgg ggctttccgt
     4861 ccaacaaatg ccatctgaag cgcggcggtt tgccgtcggc gcggtgtcgg attttattgg
     4921 gtaactttgt tcagaccgcc gcccgtcaga ttgtcaaaac ccggtttcag gcggtatggc
     4981 ggattcggtt taacgtttca acgccagcac caacacgccc gccgttacca gccccaagcc
     5041 tatccattcc tgcgtgttcg ggcgttcgtc caagaaaacc accgccatca gcgcgaccaa
     5101 gaccaggctg aatttgtcga tgggggcgac ttgcgaggcg ttgcccagtt gcagggcttt
     5161 gaagtaggcg agccaggatg cgccggtcgc caaacccgac agaattaaga atgtccagtt
     5221 ttttcctgta aatccgttca cgccctgcca tttgccggtg taggtcaaaa acagtaccaa
     5281 agcggcgagg atcaccaagg tgcggataaa ggtggcgaaa tccgaatcga tgccctgcaa
     5341 acccattttg gcgaaaatgg cggtcagcga ggcgaagcct gccgatgcca atgcccaaaa
     5401 cagccatgcg ttgctgccca tgttttctcc ttggattgtg aacaatatga acggtatttt
     5461 tgttgcagcg tcaaaaattt cactgcgggt ttggtgcgga taacgttata atatgcctga
     5521 tattattttc aatccacctg tttgtcgcct gatgctttca gacggtatgt ccctcctcat
     5581 ttctaaagga aaatcatgag cttcaaaacc gatgccgaaa tcgcccagtc ttccaccatg
     5641 cgcccgattg gcgaaattgc cgccaagctg ggcctgaacg ccgacaacat tgagccttac
     5701 ggtcactaca aagccaaaat caatcctgcc gaagcattca agctgccgca aaaacaaggc
     5761 cgtctgattt tggttactgc cattaatccg actcctgcgg gtgagggtaa aaccacagta
     5821 accatcggtt tggcggatgc gttgcgccat atcggcaaag actcggttat cgccctacgc
     5881 gaaccttctt tggggccggt gttcggtgtt aaaggcggtg cggcaggcgg cggctatgcc
     5941 caagttttgc cgatggaaga catcaacctg cacttcaccg gagattttca cgccatcggt
     6001 gcggcaaata atctgcttgc cgcgatgctc gacaaccata tctatcaggg caacgagttg
     6061 gacatcgacc ccaaacgcgt gctgtggcgg cgcgtggtcg atatgaacga ccgccagttg
     6121 cgcaacatca tcgatggcat gggtaaaccc gttgacggtg tgatgcgccc cgacggtttt
     6181 gatatcaccg ttgcctccga agtgatggcg gtattctgtc ttgccaaaga catcagcgat
     6241 ttgaaagagc gtttgggcaa catccttgtc gcctacgcca aagacggcag ccccgtttat
     6301 gccaaagatt tgaaggcaca cggcgcgatg gcggcattgc ttaaagatgc gattaagccc
     6361 aacttggtgc aaaccatcga aggcacgccc gccttcgtac acggcggccc gttcgccaac
     6421 atcgcccacg gctgcaactc cgtaaccgca acccgtctgg cgaaacacct tgccgattac
     6481 gccgtaaccg aagcaggctt cggcgcggac ttgggcgcgg aaaaattctg cgacatcaaa
     6541 tgccgccttg ccggtttgaa acctgatgcg gctgttgtcg tggcgactgt ccgcgcgttg
     6601 aaatataacg gcggcgtgga acgcgccaac ctcggcgaag aaaatttaga cgctttggaa
     6661 aaaggtttgc ccaacctgct gaaacacatt tccaacctga aaaacgtatt cggtctgccc
     6721 gtcgtcgtcg ccatcaaccg cttcgtgtcc gactccgatg ccgagttggc gatgattgaa
     6781 aaagcctgtg ccgaacacgg cgttgaagtt tccctgaccg aagtgtgggg caaaggcggc
     6841 gcgggcggcg cggatttggc gcgcaaagtc gtcaacgcca ttgaaagtca aaccaataac
     6901 ttcggtttcg cctacgatgt cgagttgggc atcaaagaca aaatccgtgt gattgcccaa
     6961 aaagtgtacg gcgcggaaga tgttgatttc agcgcggaag cgtctgccga aatcgcttca
     7021 ctggaaaaac tgggcttgga caaaatgccg atctgcatgg cgaaaaccca atactctttg
     7081 agtgacaacg ccaaactgtt gggctgcccc gaaggcttcc gcattaccgt gcgcggtatc
     7141 actgtttccg caggcgcagg tttcatcgtc gccctgtgcg gcaacatgat gaaaatgccc
     7201 ggcctgccca aagttccggc tgccgagaaa atcgatgtgg acgaacacgg cgtgattcac
     7261 ggcttgttct gagcggtttt tgaaaccgga tgccgtctga agccgtttca gacggcattt
     7321 tttcggaacg cgagcggcgg tatgctataa tccgccgtta aatttctcta ttttcaggaa
     7381 aaaacatgag tttgaaatgc ggcatcgtcg gtttgcccaa cgtcggcaaa tccaccctct
     7441 ttaacgcgct gacccaatcg ggtatcgaag cggcaaacta tcctttctgc accatcgaac
     7501 ccaacgtcgg catcgttgaa gtccccgatc cgcgtatggc tgaattggca aaaatcgtca
     7561 atccacaaaa aatgcagcct gccatcgtcg aatttgtcga catcgccggt ttggttgcag
     7621 gtgcaagcaa aggcgaaggc ttgggcaacc agttcctcgc caacatccgc gaaaccgatg
     7681 cgattgtgaa tgtcgtgcgc tgctttgacg acgacaacat cgttcacgtt gcaggcaaag
     7741 tcgatccgat tgccgacatc gaaaccatcg gtacggagtt ggcgcttgcc gacttggcca
     7801 gcgtcgaaaa agccatcgtc cgcgaagaaa aacgcgcacg ctcaggcgac aaagacgcac
     7861 aaaaactggt cgatctgtgc aaaaaactgc tgcctcatct ggacgaaggc aagcctgtac
     7921 gctccttcgg tttggacgca gaagaactcg ccatgctcaa gccgctgttc ctgctgactg
     7981 ccaaaccggc catgtatgtc ggcaacgttt ccgaagacgg ttttgaaaac aacccgcacc
     8041 tcgaccgcct gaaagaattg gctgcaaaag aaaacgcgcc ggttgtggct gtatgcgccg
     8101 caatggaaag cgaaatcgcc gaattggaag aggacgaaaa agccgaattc ctcgccgaaa
     8161 tgggcttgga agaaccgggc ctgaaccgcc tgatccgcgc cggctacgac ctcttgggct
     8221 tgcaaaccta ctttaccgcc ggcgtaaaag aagtccgcgc ctggaccatc cacaaaggcg
     8281 acaccgcacc acaagccgcc ggcgtgattc acaccgactt tgaacgcggc ttcatccgcg
     8341 cccaagttat ctcctacgaa gatttcatcg ctttaggcgg cgaagccaaa gccaaagaag
     8401 ccggcaaaat gcgcgtagaa ggcaaggaat atgtcgtgca agacggcgat gtgatgcact
     8461 tcttgtttaa cgtgtaaatt gtatacgata attattttaa cagtaactaa agtgaggttt
     8521 gaccatgact ggaaaaaatt atctaaaaag aatggatttt ggtaatgaag ctgctgatga
     8581 tgttgatgat gaagaattaa aatcatattt tgtaatgcag gaaggattcg aaaatttttt
     8641 aaaagaaaat aaaagattac aggtaattaa agccaaaaaa ggcatgggta agtctgcatt
     8701 aatcaaatgg attggtcttg aggtttctga aaaatatcag aatgctttag taatcaaaat
     8761 acgaggtagt gaactgtctc gtgaaaattt caaacttaca aaaaaactaa ctgaaccaaa
     8821 tgattatatt agcgactgga ttattagatt atgtgcagtt gtaaaccgtg aattagcaaa
     8881 gaaaataaat ttcgcatata gagatgatga aatttcttta gttgaatcta ctgaagtgca
     8941 aggttttaag gaaagaaatc ttatatcttg tcttttggaa agatttaaaa atattcttgg
     9001 taaatttcag ccagaaccaa ccactaatat taatcatcct gaaattttaa agagaataga
     9061 gtctcttgat tattcaaaaa tttggatatt aattgatgat ttagatgcaa cttttcaaaa
     9121 tactaataaa gaaaaagtga atttaggcag ttttttttca gcatgtcgtt atatgattca
     9181 ggatttaaag ggtgtgaact tcagaataac cctgcgtagt gatgtctggc ctgtaatcag
     9241 aagacacgac gaagccatgg ataaaattga acaatacata tcagaaattg aatggacaga
     9301 agaggatttt aaacaaattt tatgccgacg aattcaaaaa gaatttcctg atgattcaat
     9361 taacttaacc gatgatgaat tattaaaaaa aatttttaag cctactgttt tttggaatga
     9421 aaaacaggtt cctacttatc aggttctata tattttggca tataatcgcc caagatgggg
     9481 agttcagctc tgtaaacttg cacaagctga tgctctaaga aaaagtatgc ttcatatcga
     9541 aaaattgaat attgatgcac gttggggaga gtatggttta aaacgaattg cagatttagt
     9601 agtcgaacat aagcatcaat gtatccagat tgaagattta attaattatt ttcgaggatt
     9661 agaaagaaga ttctctcaac cagatttact tgaacttctt agaaaaaaag ttctagggtc
     9721 tatgactatt caaatagacg gacaaacaat tcaaaaaagt aaaccggaag ctatcgcaga
     9781 ttttttattt cgtatcggtt tcattgtagc tcgggcagaa gaagaacact atggatacca
     9841 tcactattcc tattcagaat taccagatct attttctggt aaaaatagtg atggattcag
     9901 cttaatgtgg gaaatccatc cctgttatcg agaagcacta aatattaaaa aattaaatgc
     9961 tgagcaaaga aatcaaaaaa atctatccca ttaatttaag agctatttaa ccacttatga
    10021 cctccgttat ccaagatttg aaagcacgcg gccttatcgc gcaaaccacc gacatcgaag
    10081 ccttagacgc tttgttgaac gaacaaaaaa tcgcccttta ctgcggtttc gatccgaccg
    10141 ccgacagcct gcacatcgga cacctgctgc ccgtattggc attgcgccgt ttccaacagg
    10201 cggggcatac gccgattgct ttggtgggcg gcgcgaccgg tatgatcggc gaccccagct
    10261 tcaaagccgc cgaacgcagc ttgaattccg ccgaaactgt tgccggctgg gtggaaagta
    10321 tccgcaacca attaacccct ttcttgagct ttgaaggcgg aaatgccgcc attatggcga
    10381 acaatgccga ctggttcggc agcatgaact gccttgactt cctgcgcgac atcggcaagc
    10441 atttctccgt caacgccatg ctgaacaaag aatccgtcaa acagcgcatc gaccgcgacg
    10501 gcgcaggcat ttccttcacc gagttcgcct actccctgct gcaaggctac gactttgccg
    10561 agttgaacaa acgccacggc gcggttttgg aaatcggcgg ctccgaccaa tggggcaaca
    10621 tcaccgccgg tatcgacctg acccgccgcc tgaatcaaaa acaagtgttc ggcctgaccc
    10681 tgcctttggt taccaaatca gacggcacca aattcggcaa aaccgaaggc ggcgcggtgt
    10741 ggctgaacgc aaaaaaaacc tcgccgtacc agttctacca attctggctg aaagtcgccg
    10801 atgccgatgt gtataaattc ctgaaatact ttaccttcct gtccatcgaa gaaatcgatg
    10861 ccatcgaagc caaagacaag gcaagcggca ccaagcccga agcgcaacgc atcctcgccg
    10921 aagaaatgac ccgcctgatt cacggcgaag ccgccctgca agccgcgcag cgcatttccg
    10981 aaagcctgtt tgccgaagac caaagcagcc tgaccgaaag cgacttcgag cagctcgccc
    11041 tcgacggcct gcctgcattt gaagtttcag acggcatcaa tgtcgtcgaa gccttggtaa
    11101 aaaccggttt ggcatcctcc aataaagaag cgcgcggctt tgtgaacagc aaagcggttt
    11161 tgctcaacgg caaacctgcc gaagccaaca accccaacca cgccgccgaa cgccccgacg
    11221 atgcctgcct gctgaacggc gaacacaaac gtttcggcaa atacactatc cttcggcgcg
    11281 gcaaacgcaa ccacgcgctt ttggtttgga aataatccga ttgccgcaga aatgccgtca
    11341 ttcccgcgca ggcgggaatc cggacctgtc cgcacggaaa cttatcgggc aaaacggttt
    11401 cttagattcc acgttctaga ttcccgcctg agcgggaatg acgagtttca agattacggt
    11461 gttgtcggaa cgcaactgaa ccgtcattcc cacgaaagtg ggaatctaga atctcggggt
    11521 ttgagcaact gtttttatcc gataagtttc tgtgcggaca ggtccggatt cccgcctgcg
    11581 cgggaatgac ggcggagggt tgcttgtctc ggtttacctg gttaaaaaag aacgattttc
    11641 actgatgttg catcaggttt ggggcgatgt ttcaacacat agcaccgcgc ctgctgcgcg
    11701 ctttatgcgt ttggcgcgtt cggctgcggg aaatttgcct acttttcccg cgtcgggcgg
    11761 gcgtaacggg cggcacactg tctataaacc gcaataccgt ttacaatgac cgcctgtttc
    11821 accacatacc cgaacataac aatgagaatc aggctggggc ggcacaacgc gcccgacttt
    11881 ccgcacgggg ccgccgtaac cataggcaat tttgacggcg tacacctcgg acacaaacac
    11941 atcctccaaa aactccgcct cgaagccgat acgcgcggat tacccgtcgt gaccgtcgtt
    12001 ttcgaacccc aacccaaaga atttttcgca ctccgcaccg gcaggatgcc accgtgtcgg
    12061 atcagccccc tgcgcaccaa gctcgaatta ttggaaggca caggctgtgt cgatgccgtc
    12121 tgggttttgc gtttcgatca aaatttttcc gaaatatccg cacaagcatt tatcgaccgc
    12181 ctgctgcgtc aaaccttgaa tacgcgttat ttgctcgtcg gcgacgattt ccgtttcggt
    12241 gcggggcggg aaggctgttt tgaacttttg gcacaacagc ccgatatgca gaccgagcgc
    12301 acgccttccg tcatcgtcga agacatccgc accagcagta ccgccgtgcg acaagccctt
    12361 tcagacggca accttgccta tgcgaaaaaa cttttgggac acgactacgt cttgagcggc
    12421 agggtggtgc acggcagaaa actcggacgc accttaaacg ccccgactgc caacatccgc
    12481 ctgcccggcc accgttatgc actcggcggc gtgtttgtcg tcgaagcgga cggcgcattc
    12541 ggcacgcggc gcggcgtggc gagcttcggt ttcaatccca ccgttgatag cggctgttct
    12601 caaaagcttg aagtccacct gttcgacttt caaggcgacc tgtacggaca acggctgaac
    12661 gtccgcttcc tgcacaaact gcgcgatgag gaaaagtttg acggtatgga agaactgaaa
    12721 aggcagattg aagccgatat ggaagccgca aagtgttggt agaaaaacct tatacaaacc
    12781 atccgattgg gctacaatca accttttaac ttttcagacg gcataggggt ttcccgttgt
    12841 gaaatactgt ttgaggcgca atgccgtctg aaccgaaata ttgtaacaat agagattaaa
    12901 aaatgaccga ttacagcaaa accgtcaacc tgctcgaaag cccgttccca atgcgcggca
    12961 atcttgccaa gcgcgagcct gcatggctga aaagctggta cgagcaaaaa cgctaccaaa
    13021 aactgcgcga aatcgccaaa ggccgtccga aattcatcct gcacgacggc ccgccgtatg
    13081 ccaacggtga catccacatc ggtcatgccg tcaataaaat tctcaaagac atcattatcc
    13141 gcagcaaaac ccaagccggt ttcgacgcgc cttatgtgcc gggttgggac tgccacggcc
    13201 tgcccatcga agtgatggta gaaaaactgc acggcaaaga tatgcccaaa gcacgtttcc
    13261 gcgaattgtg ccgcgaatat gccgccgaac aagttgcccg ccagaaaaaa gactttatcc
    13321 gcttgggcgt gttgggcgac tgggacaagc cctacctgac gatggatttc aaaaccgaag
    13381 cagataccgt gcgtatgctc ggcgaaatct acaaatccgg ctatctctac cggggcgcga
    13441 aaccggttca attctgcttg gactgcggtt cttcgctggc ggaagcggaa gtggaataca
    13501 aagacaaagt atcgcctgcg attgacgttg cctatccgtt taaagacacc gccgcgcttg
    13561 ccgccgcatt cggtttggca ggtatcgaag gcaaagcgtt tgccgttatt tggacaacca
    13621 cgccttggac gctgccggcg agccaagccg tgtctgccgg tgcggacgtg gtgtatcaat
    13681 taatcgatac gcccaaaggc aaattggtgc tggcgaaaga tttggcggaa gacgcgctca
    13741 aacgttacgg tttttcagac ggcattgcta ttcttgccga aactaccggc gacaagctgg
    13801 aaaacctgca catgaatcat ccgttcctcg aacgcgatat tcccatgctc aacggcgacc
    13861 atgtgaccac cgatgccggt accggcttgg tgcatactgc gcctgcgcat ggtctggaag
    13921 actacactgt ctgcaataaa tacggcatcg agctttacaa ccctgtcaac gccgaaggca
    13981 aatacattag cgaaacgcca cgcgttgccg gtatgcgcgt ttgggaagcc aatcccatta
    14041 tcctgcaatg gctggaagaa accggcaacc ttttggcaag cagcaaaatc gaacacagct
    14101 atgcccactg ctggcgccac aaaacgccgc tgatttaccg cgcgacaggt caatggtttg
    14161 tcggtatgga caaagccggt gccgacggta aaaccttgcg cgacaaagcc atcaaagccg
    14221 tggacgacac cgaattcttc ccatcatggg gtcgcgctcg actcgaagcc atgatcgaag
    14281 gccgtcctga ctgggtggtt tcacgccaac gttactgggg cacgccgatg actttctttg
    14341 ttcacaaaga aacgggcgag ctgcatccga actctgccga gcttttggaa aaagttgccc
    14401 tgaaaatcga agaaaaaggc atcgaagcgt ggttctccct cgataagagc gaactcttga
    14461 gcgcggaaga ttgcgaaaat tacgataaac tttccgacac aatggacgta tggttcgact
    14521 caggctcgac ccattattcc gttgtgaaac aacgcgaaga attggaatgg ccggctgact
    14581 tgtacctcga aggcagcgac caacaccgcg gctggttcca atcctctatg ctgaccggtt
    14641 gcgcctcatc catgggacgc gcaccgtata aacagctgct gactcacggt ttcgtggttg
    14701 accaaaacgg tcgcaaaatg tcgaaatcta tccgcaacgt cgtcgcgccg caggaagtgt
    14761 ataacgagtt cggagcggac attttgcgcc tgtgggcggc atccaccgat tacagcggcg
    14821 aattgtcgat ttccaaagaa atcctcaagc gcgtaaccga aagctaccgc cgtatccgca
    14881 acaccttgag cttcctgttt gccaacctca gcgacttcaa tcctattgaa gatgccgtgc
    14941 aacaggcaga catggtggaa atcgaccgct acgccttggt attggctcgt cagctgcaag
    15001 agcgtctggc aggcgattac tatccgcgtt ataccttcca cttcgccgta aaagatattg
    15061 tttctttctg ctcggaagac ttgggcgcgt tctacctcga tatcctgaaa gaccgcctct
    15121 ataccaccaa agccgacagc cgcgcccgcc gcagcgcgca aaccgccctg tatcacatca
    15181 cacgcagcct ggttctcttg attgcaccga ttttgtgctt caccggcgaa gaagcgtggg
    15241 acatcatcgg cggcggcgaa gaagacagcg tcctcttcca cacttggcac gagttcccga
    15301 ccatcaacga aaaagccgaa gccgaactgg tgaaaaaatg gacggcaatc cgcgaagccc
    15361 gcgaagccgt taccgccgcc atcgagcttt tgcgcgccga caaaaccgtc ggttcgtcct
    15421 tgcaagccga agccgaaatc actgcgccgg aagaaatggc cggctacctg aacgctttgg
    15481 gagaagagtt gcgttttgcc ttgctggtgt ctaaagcaga agtgaaagta ggtgatgaac
    15541 ttgctgtaac cgctaaagcc agcgatggtg aaaaatgcga acgctgctgg cactacaccc
    15601 acgatgtggg cgcagttgca ggctatgaaa ccgtctgcaa acgctgtgca gagaatgtcg
    15661 gcggagaagg cgaaacgcgc cattacgcct gataaagttt gagcaaatgc cgtctgaaac
    15721 cgccgaacag catttcagac ggcatttttt gtgccgcgat ttgtctttat aacggcggag
    15781 gggtttcaag attgcggtgt tgtcggaatg caactgaacc gtcattccca cgaaagtggg
    15841 aatctagaat ctcgaggttt cagtcatttc cgatagattc ccgccgcgtc ggaggtctgg
    15901 attcccgcct gcgcgggaat gacggatttc gagattgcgg tgttgttgga acgcaactga
    15961 accgtcattc ccacgaaagt gggaatctag aatctcgagg tttcagtcat ttccgataga
    16021 ttcccgcctg cgcgggaatg acggatttca agattacggt gttgtcggaa tgcaactgaa
    16081 ccgtcattcc cacggaagtg ggaatctata gtggattaaa tttaaatcag gacaaggcaa
    16141 cgaagccgca gacagtacaa atagtacggc aaggcgaggc aatgccgtac tggtttgaat
    16201 ttaatccact atagaacgcg gggtttgggc aactgttttt atccgataag tttctgtgcg
    16261 gacaggtctg gattcccgcc tacgcgggaa tgacgggttt cgagattacg gtgttgtcgg
    16321 gaatgacggg ttttaagatt acggcatttg ccgtttcggg tacaggaaag ggggttttcg
    16381 ggtaaaatgg tactctttta ccggctgttg aaaaatatgt cttcatctgt ttcaagtaaa
    16441 acgcgctatt gggtattggc acttgccgcc atcgtgctgg accagtggtc gaagtgggcg
    16501 gtgctgtcgt cgtttcagta tcgggaacgc gtcaatgtca ttccttcctt tttcgatctg
    16561 acgctggtgt acaacccggg tgcggcgttc agcttccttg ccgatcaggg cggctggcaa
    16621 aaatactttt ttttggtgct ggcggtggcg gtgagcgcgt atttggtacg cgccatcttg
    16681 cgcgatgagt ttgcaaccct cggcaaaacg ggtgcggcaa tgattatcgg cggtgcgtta
    16741 ggcaatgtca tcgaccgcct gatacacggt catgtcgtcg atttcttatt gttttattgg
    16801 caaaattggt tttatcccgc ctttaatatt gccgacagct ttatctgcgt cggtgcggtg
    16861 ttggcggtgt tggacaacat cgtccaccgt aaaacccaag aagaaaaata ttgatgccgt
    16921 ctgaaaacga aataccgggc ttatgaacga gaaaaccatc atccttgcca atccgcgcgg
    16981 cttctgcgcc ggtgtggatc gggcaatcag tattgtcgaa cgtgctttgg aagagttcgg
    17041 cgcgccgatt tatgtgcgcc acgaagtcgt tcacaacaaa ttcgtcgtgg acaacctgcg
    17101 tgaaaaaggt gcggtgttta ttgaagactt ggcggaagtg ccgccgggcg cgacactggt
    17161 ttattcggca cacggcgtat cgaaggcggt gcggcaagaa gcggcggagc gcggtttccg
    17221 cgtgtttgat gcgacttgcc cgctggtgac gaaagtgcat aaggaagtcg cccgactgga
    17281 tgcccaagac tgtgaaatca tcatgatcgg gcataagggg cacgtcgagg ttgaaggaac
    17341 gatggggcag cttgcgccgg gcaaaatgct tttggtcgaa acggtcggag atgtggcaaa
    17401 actcgaagtc agaaaccccg acaaactcgc ctatgtcagc caaaccacgc tctcggtcga
    17461 tgaaaccaaa gacatcatcg ccgcgctgaa cgcgcgtttc cccaatatcc gcaatccgca
    17521 caaggaagac atctgctatg cgacgaccaa ccggcaaacc gccgtcaaag agctggcgga
    17581 acagtgcgac atcgtgattg tggtcggttc gcccaattcg tccaacagca accgcttgcg
    17641 cgaagtggcg gcatcgcgcg gaatcgatgc gtatatggtg gataatgcag gctacctgca
    17701 acgcgcatgg tttgagggca aaaacaaagt cggcgtaacg gcaggcgcgt ccgcgcccga
    17761 agtgttggtg cgggaagtac tggcaaccat acgcggatgg gggcacgaaa ccgtacgcga
    17821 aggcgagggt gcggaagaaa gcattgtgtt cgtcctgccc aaagagctgc gccgcgaggg
    17881 cgaaaccaaa cccgatttgt gcaaacgttg agcaagcgtt gaatgtttgg gcaacacaaa
    17941 tgccgtctga acaggcttca gacggcattt ttgccgcgtg ccggatgcgg aaaccaatca
    18001 ggcgtaatgt cgtgcaagaa aaccgggcag ttcggacaaa ccgtccaata cggcgagatg
    18061 cggtgcggtg cggagctgtt cgcgcgaatg tgcgccggtg gtcacgccga ctgccgccgc
    18121 ccccgcgttt gccgccatat gcaggtcgtg cgccgtatcg ccgacgacca atgcttcttt
    18181 cggatcgagt cccagttcgc cgcagattcc gaataccatt tcgggcgagg gtttggaggg
    18241 atattccccc gcgcaggcgg tggcgagcca atagccgccg gtggcggttt ggctgatggc
    18301 gttgtccaag cccgcccgcc ctttgcccgt ggcgacggca agccagtatc cttgtgcttt
    18361 gagcttgtcc agacagggca gggcatcggg aaagagcgtc atattgcggt tgttgggatt
    18421 gaggtaatgt gcggaataag tgcgtgtgat gtcggcaatg gcggtttcag acggcatttc
    18481 gagcagggtg cggatgattt cgggcaggct gtagccgatc aggctgcgga cgcgctccgc
    18541 ttcgggcggc ggaaaaccgc attcggcgaa gctgcggcgc atggtgtcga tgatgggttg
    18601 ggtcgtgtcg gcaagcgtgc cgtcccagtc gaagatgatg agtttgggcg gggtcatagc
    18661 aggttggttg cagtaaaaaa gcagatttta tgcggaaaac gcagacgtgt cgcattttcg
    18721 acaaaatttg tcggctgcgc gatatgtttt tccgaacaag ctgcgttgtg ctttattaaa
    18781 atagaaccat tatcatttat gtgaatggga cagtttatgt cagttttccg catcaatatg
    18841 accgccgcca cggttttggc agcactttcg tcttcggttt ttgccgcaca aacggcggat
    18901 ttggaaaccg tccacatcaa agggcagcgt tcgtacaacg cgattgccac cgagaaaaac
    18961 ggcgattaca gctcgtttgc cgtcaccgtc ggcacaaaaa tccccgcttc tttgcgcgaa
    19021 attccgcaat ctgtcagcat catcaccaat caacaggtca aagaccgcaa tgttgatacg
    19081 tttgaccagt tggcacgcaa aacgcccggc ctgcgcgtgt tgagcaacga cgacggacgc
    19141 tcttcggttt acgcgcgcgg ttacgaatac agcgaataca acatcgacgg cctgcccgcg
    19201 cagatgcaga gtatcaacgg cacgctgccc aatctgtttg ccttcgaccg cgtggaagtg
    19261 atgcgcgggc cgagcggact gttcgacagc agcggcgaga tgggcggcat cgtaaatctg
    19321 gtgcgcaaac gcccgaccaa agcgttccaa ggacatatgg cggcagggtt cggtacgcac
    19381 aaacaatata aagccgaggc ggacgtatcg ggcagcctca attcagacgg cagcgtgcgc
    19441 ggccgcgtga tggcgcagac cgtcggcgcg tctccccgtc ccgccgagaa aaacaaccgg
    19501 cacgaaacct tctacgcggc ggcggattgg gacatcaacc ccgatacggt tttgggcgcg
    19561 ggctatcttt accagcaacg ccacctcgcg ccgtacaacg gcttgccagc cgatgccaat
    19621 aacaaattac cgtccctgcc gcaacacgta tttgtcggcg cggattggaa caaatttaaa
    19681 atgcacagcc acgacgtgtt cgccgatttg aaacattact tcggcaacgg cggctacggc
    19741 aaagtcggta tgcgctattc cgaccgcgat gccgactcca actatgcctt tgccggcagc
    19801 aagctgggca tgaaaacccc ggcaggccgc ccgggctgca atacggctga cgacaaagcc
    19861 tgcgcggtgg gtttgggtac agaaatcaaa caaaaagccc tcgcgtttga cgccagctac
    19921 agcaggcctt tccgcttggg caatacggcc aacgaatttg tcatcggcgc cgattacaac
    19981 cgcttccgca gcaccaacga acaaggccgt actactttat atgcacgcgg cggcctggct
    20041 ttaaacgagt tccgcagcat accgcaggtt gatttgattg ccaacgcgcg caaaggcgtg
    20101 cgcggttaca gccataccgt cgctaccgaa aacctcgacg aattcggcat ttacggcaaa
    20161 tccaccttcc atcctgccga cgggctgtcg ctcatcggcg gcggacgttt gggacactac
    20221 aaaatcgagt cgggcgaagg cgacgagttg cacaaagcca gcaaaaccaa gttcaccggc
    20281 tacgcaggcg cagtttacga cttgaacgac aacaacagcc tctacgccag cttctcccaa
    20341 ctctacacgc cgcaaaccag cctcggcacc gacggcaagc tgctcaaacc gcgccaaggc
    20401 aaccagtttg aagtcggtta caaaggcagc tacatggacg accgcctcaa tgcccgagtt
    20461 tcgttctacc gcatgaaaga caaaaacgcc gccgcaccgt tgaacccgaa caacaaaaaa
    20521 acccgttacg ccgcattggg caaacgcgtg atggaaggcg ttgagaccga aatcagcggc
    20581 gcggttacac cgaaatggca aatccatgca ggttacagct atctgcacag ccaaatcaaa
    20641 accgcctcca attcacgcga cgacggcatc ttcctattga tgcccaaaca cagcgcaaac
    20701 ctgtggacga cttaccaagt tacgcccgag ctgaccatcg gcggcggcgt gaacgcgatg
    20761 agcggcatta cttcatctgc agggatgcat gcaggcggtt atgccacgtt cgatgcgatg
    20821 gcggcatacc gcttcacgcc caagctgaag ctgcaaatca acgccgacaa catcttcaac
    20881 cgccattact acgcccgcgt cggcggcgcg aacaccttta acattcccgg ttcggagcgc
    20941 agcctgacgg caaacctgcg ttacagtttt taaagaccaa tatgccgtct gaaacggcag
    21001 ccgcagcatc atcaaaccac aacaagctgc gctgcatacc ctatgctctc acaactggag
    21061 tatggcattg cgaaggaaaa cagaccgaac cggcaggcag accgctttgc cggttcggtt
    21121 ttaccgcttg ccgccagtct gacccacaag ccgaacatca tgaaacccat accgaccgac
    21181 acattccaac ctgccatact gccccaagcc tttgaaaccg aaatcaaatc cacctgcacg
    21241 gggcgaatct atcggattca gacggcgaca ctcggcgaaa tgccgtctga aggctatccc
    21301 gtcctcttcg ttttggacgg cgaagccttt ttccccgcac ttttcaacat catgcagtcg
    21361 ctgatgccca accccgttac ccgaagcaac gccccctgcc tgattgtcgg tatcggctac
    21421 acgacaggca gtgtgcgcga tttggcacaa cgtgccgccg actacacgcc gccgcttgga
    21481 gacaacgcca cagcagacga acggcagcag ttcggacagg cagaccgctt ctccgccttt
    21541 atcgacagcg agctgaccgc ctttttagaa agccgctaca ccctcaaccg caatgaaacc
    21601 gccgtattcg gacactcgtt cggcgcactg ttcggactgt attccctgct ttcccaccgc
    21661 cgtttcagac ggcattggct cgtatcccca tcgatttggt ggcacaacag gcggatactc
    21721 gattttatgc cgtctgaaaa ccggctaaac ggcatcgatg tctgcctcaa catcggcgcg
    21781 ctcgaacggg gtagcggttg caaacgcagg gaaaaacgcg atatggcagg actgtccgaa
    21841 cgcatggcgg cagagttgga caggcacggg gccgccgtct ttttccggga atatccgaat
    21901 gccgaccacg gcaatgtctc gttctactcg ctgaccgatt gcgtcgaata tttgaggaag
    21961 gcttggcaga ggtaggggga attaaatata tgactgcttt gttttgcatc ggaaaataac
    22021 aagagctacc taagggttat tgctcccttt ctcattttat tttgatataa aaatccctgc
    22081 ttcaggccgt ctgaaacagg gataggttaa tttaacggac gggtgggcgt tttttcaggc
    22141 ggcacggtct gatttctttg cccggtttgt cgatttggta tttttggagt gaaagggcgg
    22201 ttttgatacc gatactttgg aaaatgccgt ttttcccttt ggtgctgtct gtgtcatgca
    22261 cacggatatc aatcgtcccg gttgctctat ttagactggc gaaataacca aaaaatacgt
    22321 ttttcttggc agttactttt attcaatcat tcgaataaag tacgaatgaa accggttttt
    22381 gggcttcaga cggcatttct atttttggtt accagttgac gcgcaccgac cggctgccga
    22441 gcaatgtttc cagttcgccg aacaatgcgg agctcggtgt aaccgtccat ttcggcggca
    22501 cttgaagcct gcccgacgct ttttcgttgg catacgacag ttgcagcggg atgcgcggcg
    22561 tgtcgggcag ttggtgggag gagagcagcc gtaccagtcc gccgatgtcg tgatgcgggg
    22621 cgagggcgag actgaggctg cgggcgtagc gttcgcgcgc cgtttgcagg gtcatgactt
    22681 ggtttgccat gatgcgcagt ccgtcgccgc cgccgtagtc gtcgcggctg actttggatt
    22741 cgataatcag cacttggtcg gctttgaggc agtcggcgca gttttccagc gtctggccgc
    22801 tgaccatgat ttcaatctgc ccgctcaaat cttcgaggct gacgaaggcg attttgccgc
    22861 gtttgcccat catggtgcgt acggcggtaa caaacccggc gaggcgcacg ctgtcttgcg
    22921 gtttgagttt cgacagtttc tgcggggcga tttggcggac ttcttgggca tacgggccga
    22981 acgggtggcc ggacaggtaa aagccgatga cggttttttc ttcggcgagt ttttccgatt
    23041 cgctccacat cggcgcgtca atgagccgca ccggttcgat ggcgtcttcc atcatgtcga
    23101 aaagtccgcc ctgattggcg ttggcggctt tttggtcggc gttgttcatg gcgaggtcga
    23161 tgttcgccaa gagcatggcg cggttgggtt cgatgctgtc gaacgcgcca ccgcgtatca
    23221 gggcttcaag ggtgcggcgg ttcatgtgtt ctttgccgac gcgctcgcag aagtccaaga
    23281 ggccggtaaa cttgccgccg ctttgccgcg cggaggtgat ggattcgacg gcggcttcgc
    23341 ccgtaccttt aatcgcgccg agcgcgtagc ggattttcat gtccggatac ggcgtgaagc
    23401 ggtagtcgga ttcattgatg tcaggcggca gaaactcgat gccgttggcg cggcagtcgt
    23461 cgtagaaatg cttgagctgg tcggtgttgt ctaattcaga cgacatggtt gccgccataa
    23521 attcggcggg gtagtgggct ttgagccatg cggtttggta ggaaatcagg gcgtaggcgg
    23581 cggcgtggga tttgttgaaa ccgtagccgg cgaatttttc catgtagttg aagatttcgt
    23641 cggatttttc gcgcgaaatg ccttgttttg ccgcgccttc ggcgaagatt tcgcggtgtt
    23701 tcaccatttc ttcgggtttt ttcttaccca tcgcgcgacg cagcaggtcc gcgccgccga
    23761 gcgagtagcc gccgataatc tgagccgcct gcatcacttg ttcctgatac accataatgc
    23821 cgtaagtcgg cgcgaggatg ccttcgagca gcggatggat gtattggaat tcctgtccct
    23881 tcatgcgcgc gacgaagtcg gggatgttgt ccatcgggcc ggggcggtag agcgatacga
    23941 aggcgatgag ttcttcaaac ttggtcgtat gcgccgtttt cagcattttt ttcatgccgg
    24001 tcgactcaaa ctggaacacg gcggtggtgt tcgcatctcg gaagatttgg taggcggcct
    24061 ggtcgtcgag cggaattttg ccgacatcga taatgtcgcc ggtggtgttt ttgatgttgt
    24121 cctgcgccat ttcgataatg gtcaggttgc gtaggcccaa aaagtcgaat ttcaccaaac
    24181 ccacgtcttc cacgtcgccc ttgtcgtaca tggatacggg cgaggcggat tcgtccgcct
    24241 gatacacggg gctgtaatcg gaaatcttgc caggcgcaat caacacgccg cccgcgtgca
    24301 tacccaaacc gcgcgtcagg tcttccagct ttttcgccag cgtaatcagt tcgtccgctt
    24361 cttccgcttc gattaattcc tgaatctgcg gctccgcctt catcgcgtcg tccaaaccca
    24421 gaggtttgtt ggcttccagc ggaatcagct tggacagttt gtcgcacagg gtaaacggca
    24481 gctccaacac gcgccccacg tcgcggatga ctgctttgga cgacatcgtg ccgaaggtaa
    24541 caatttggct gaccgcctcc gcgccgtatt tctcgcgcac atattcaatc acgcggccgc
    24601 ggttgctttg gcaaaagtcc acgtcaaagt caggcatgga aacgcgttcg gggtttaaga
    24661 aacgttcgaa cagcagcgcg tatttgagcg gatcgaggtc ggtaatcttc agcgaatacg
    24721 ccaccagcga acccgcgccc gaaccgcgtc ccggcccgac cgggcagccg tgtgttttcg
    24781 cccagttgat aaagtcttgt acgataagga aatagccggg gaatttcatc tggatgatga
    24841 tgttcagctc aaaatccaaa cgttcctgat attccggcat tttttccgca cgttccgcct
    24901 cgtcgggata aagctgaacc atgcgttcct gcaagccctc attggagagt ttgatgagat
    24961 agtcatcgag tgataaaccg tcgggcgtgg ggaaaagggg caggaagttt ttgcccaatg
    25021 tgatgtgcag attgcagcgt ttggcaattt ccaccgtgtt ttcgagggct tcgggtaaat
    25081 cggcgaaacg ttcggccatc gtttccggcg gaatgaaaaa ctggctcggt gtgaaatcgc
    25141 gcggacgttt cttgtccgtc aatacccagc cgcctgcgat acacacccgc gcctcgtgcg
    25201 cgttgaaatc gtcgcggctc ataaactgcg tcggatgcgt cgccaccacc ggcaaaccca
    25261 gttcctccgc cagcttcacg ctgccggaaa cgcaagcctc ccattcgggg cgttcgggca
    25321 ggcgttgcag ctctaaataa aacgcatcgg gaaaccatgc cgcatatttc aacgccgccg
    25381 cgcgcgccgc gtcttcattg ccgttcaaca gattcatgcc cacttcgccg taatgcgcgc
    25441 cgctcaaaca aatcaagccg ctgttgtcgc cgttttccag ccattcgggg ttgagttccg
    25501 cgtgatggac attgcggtct ttgccgacat aggcctctgt caaaagctcg ctcaaacgca
    25561 gatagcccgc atcgttgcgg ataatcagca tagcgcggaa cggcttgtcg ggcgcattcg
    25621 gattgcctat ccacacgtcc gccgcgccga tgggcttaat ccctgcgccg cggcaggctt
    25681 tatagaattt caccaaaccg aattcgttca tcaaatcgct gatgcccaaa gcaggcaaac
    25741 cgtattcctg cgctttggca atcagttttt taatccgcac cataccgtcg gtaattgaga
    25801 actcggtatg caggcgcagg gggatgtagg tcggctcggt catggcaaaa tcggcgtgaa
    25861 caataaaagg cgtattgtag cagggttgtc tttagatggc ggtgtaggtc atgccgtttc
    25921 agattcagac ggcatgacct gcaaatgttt ttgagctttt acgacggcaa aaaaatgcct
    25981 cctaccgtgt ggtggaggct tcccaaggag tattgataga tataaaggac tatcaaacta
    26041 gttataagga actatatacc ttattcggac ggatggcaag cagttaaatt aattttacgt
    26101 tcaaacaggt ttttgatttc gttttgatgc cgattgccgg tgtatcgggc agttcgcgtt
    26161 tgaggatgtg catcagcgtc aatgcggatt cgtcggggaa caggatttgc agtctgccgt
    26221 tggacaggat ttctttgatc ggattgcggc atatggggtt tcagacggca tttttacgga
    26281 acaggcagtg cggatacatc gctggttttg cggtaatttt gggtacggcg gcggcaggtg
    26341 ctacaataac ggtctctttc tgcaagggga catcatggaa gccatcgtct atctcgaaga
    26401 caacgaatac atcgccttgt gcgacctctt gaaattggtc ggacttgccg aaagcggcgg
    26461 acaggcgaaa gcgtttatcg ccgaagggct ggtgttgcgc aacggcgaaa ccgaaacccg
    26521 taaaaccgcc aaaatacgcg gcggcgaagt catcgagttt gacggtgcgc gcttggaaat
    26581 cgccgatgga tatgaccctg aagcataaag ccgaagccct tttgggcgag ccgcttttag
    26641 acgaacccgt ccgacccgag tcgtgggaat gctgcggcag cgactgcggc gaggcgtgta
    26701 ttcagacgat ttattgggcg gataaggccc gctacgacgc gcaacggcgg aaattgaaag
    26761 aagcgggttg gtcggacgat gccgtctgaa aacggttcgg cttgatatag tgaattaaca
    26821 aaaatcagga caaggcggcg agccgcagac agtacaaata gtacggaacc gattcacttg
    26881 gtgcttcagc accttagaga atcgttctct ttgagccaag gcgagccaac gctgtaccgg
    26941 tttaaattta attcactata aaaccacgtt ttcagacagt cttttatagt agattaaaat
    27001 tgaaaacggt catatcgcca ttccctcgaa agcaggaatc cggaagtttg aaatagcggt
    27061 taaccttaaa catttccaat aaatcaaagt ctggattccc gcctgcgcgg gaatgacggt
    27121 atagggactt ttcctttgca tttgccatac acctgttttt taaaatgacc gccgccgcca
    27181 caccgcccga caatattgcc ccccgacctt cattcaccac acatataaca ccccatgata
    27241 gacctgcact gccattccac cgtttccgac ggtatgcttt cccccgccga agtcgtccgc
    27301 ctcgcgcatc aaaacggctg cacgctgctg gcgttgaccg accacgacca caccggcggc
    27361 atcgccgaag cgcgtgccga agccgacagg ctcgatttgc gcctgattaa cggcgtggaa
    27421 atctccgtca cttggcgcgg acgcaccata cacgttgtcg gtttggattt cgacgaacgg
    27481 gacgaaaacc tgcaaaacct gttggcgcaa gtgcggcaag gccgtctgaa acgcctcgaa
    27541 gccatcgccg ccaagcttga aaagaaaggc atcggcggcg catacgacgg cgcgctcgcg
    27601 ctggcggcaa acaaagaaat ggtcagccgc acacacgtcg ccgagttcct cattcgggtg
    27661 ggacacgtca aaaacaagca gcaggcgttc accaaatact tgggcgacgg caaatcctgc
    27721 gccgtccgcc acgaatgggc gacgctggaa gactgcgtct ccgccgtcaa cggcgcgggc
    27781 gggttggcgg tcatcgccca tccgatgcgc tacgatttgt ccgccaccgc caagcgcaat
    27841 ctgtttgaag aatttaaaaa cctcggcggc gcaggcatcg aagtccacag cggcaactgc
    27901 tgcaaaaacg accgcctcaa ctacgcgctt ttggcagaac gcttcggtat gctcgccagc
    27961 gcgggcagcg acttccaccg tttaaacgac tttagcggcg gcattctcgg cgcgtgtccc
    28021 gaactgccgg aaaactgcag gccggtgtgg gcgcattttt cccgatattg aatgcagata
    28081 aaaatgccgt ctgaaaacct ttcagacggc attttttgcg gtttaaacgt tgtcgtacag
    28141 ttttcggacg gttttgccga tggcggcgat gcctttttcc agcgtttgag cgtcctgcgc
    28201 gatgctcatg cggatgcact cgcccgcgtg cgggtaatcc cgcgtgtcga tgccgacgaa
    28261 gaaatgctcg cccggaataa tcagcgtacc ttcggctttg agcatttcgt acagggtttg
    28321 cgaagaaacg ggcaggtttt caaaccagag ccacaggaaa atcgcgcctt cgggtttgtg
    28381 gattttcatc gggtacgcgc ccagctcgcg cttgagcagc gagacggcgg tttgcgcctg
    28441 attgcggtaa aacggccgga tgacttggtc ggcaagccgt ttcatctcgc cgctttccag
    28501 cagcggggcg gcgatggccg cgccgaagcg cgtgggggca aggttcacaa tcgcgttcag
    28561 gctgctgacg gctttgacga cttcgggcgc ggcgacgatg atgccggtgc gaacgcccgg
    28621 caggccgact ttggaaaggc tgaagcagag gatgatgttt tcgtgccaat tcagcgttac
    28681 gtcgctgtaa atgatgttgg ggaacggcat tccgtaggcg ttgtcgataa tcagcggaat
    28741 cccgtgttct tgcgccaaag cgtccagccg cgccatttcg ctgtcggtca gcacgttgcc
    28801 ggtcgggttg gtcgggcgcg aacagcaaat cgcgccgatt ttgcccgctt tgagttcggg
    28861 caggttttcc agtgcgtcaa agtccacgcg gtatttgaag aagcctgctt cgccttcgtg
    28921 ttcgacgttt tcgattttgg gcttgacgga aacgaagtgc tgcccttcga catgcacgtc
    28981 ggcatagccg atgtattcgg gcgcgagcgg caacaaaatg gctttttctg cggatgtgcc
    29041 gtctgaaagg ttgaatttgc cgccgaagag gttgaataaa tagaaaaacg cgttttgcga
    29101 accgttggtc agcgcgatat tgtcggcggt caggttccag ccgtattcgc ggttgaggaa
    29161 ggcggtcagc gcgtcaatca gcgcggcatc tccttgagga ttggagtagt tgccgatgtt
    29221 ttcgacggca tgttctgctg ccagtttgga aaatacgtcg gcgaacacgg cattgacttc
    29281 ggcgattcgc gccggattgc cgccgccgag catattgacg ggcttgtcgc ttttgagcgc
    29341 gtcgccgagg tcgtccatca gttggaggat gccgctgtgt tgcgtgaatt tttcgccgaa
    29401 tgctgagaac tgcatgtcaa actccgtgtg tgtaaggtag gttggtttgt acgttatgcc
    29461 gtctgaaggt tcagacggca ttttttctgt gtgtttctcg tacccaaagc aggtcgcaga
    29521 tgccgtcgct cggggcaaag ccggtcgggg cgttgatgag cagggtgcgg attgcctgct
    29581 ggtcgtaacg gtcgcaggcc gcacggatgc ggtcgagcag ggcggagagc tcgtgccacg
    29641 gcagcatggt ctcgttggcg gtcatgatgc gcggatggcc ggttttgcgg acgttgtcgc
    29701 cgatgagcag ctcttcgtag agtttttctc cgggacgcag tccggtaatg aggatttcga
    29761 tgtcgccgtc gggttgttcg ggtgtgttgg gtttgaggcc gcttagggta atcatttggc
    29821 gggcaaggtc gatgattttg acggattcac ccatgtcgag gacgaatacg tcgccgcccg
    29881 tacccatcgc gcctgcctgt atgacgagtt gggcggcttc gggtatggtc atgaaataac
    29941 gtgtgatttc ggggtgggtc agggtaagcg ggccgccttc tgcaatctgt ttttcaaaca
    30001 gcgggacaac ggagccggac gaacctaaaa cattgccgaa acgtaccatg ctgaagcggg
    30061 ttttttgtcc gggttcggcg gcgagtgcct gaaggcagag ttccgccatg cgtttgctgg
    30121 cacccatggt gttggtgggg cggacggctt tgtcggtgga gatgaggacg aaagtttcca
    30181 cgcccgatgt cgtggcggca agcgcgcact cgagtgtgcc gaagatgttg ttgcgtatgc
    30241 cttcgacggt gttgaactcg accattggga cgtgtttgta ggcggcggcg tgatagacgg
    30301 tcgcaacgga aaaggcggtc atgacgtgtt cgagcagcgt gcggttttgc accgaaccga
    30361 gaaagggcag gatttcggtg tcgaggcgtt tttggatgca ggtttcgcgc aattcttttt
    30421 cgacggcgta cagggcgaat tcggataact cgaacagcag cagcttttcg gggcggcggc
    30481 ggataatctg gcggcagagt tccgaaccga tggagccgcc cgcgccggtt accatgacgg
    30541 ttttgccttc gatgtcggca ctcatcaggc ggttgtcggg cgcgacggaa tcacgcccga
    30601 gcaggtcgga cacagagatt tttttgagcg tgccgatgct gattttcccg tccatcaggt
    30661 ctttcattcc gggaatggtc aacacttcgc acggataggc ttccagtttg ttgatgattc
    30721 ggcggcgttg ttcctgggtc gcgccgggga tggcgagtag gattttttcc acgccgtagc
    30781 gttcgatgag gaaggcgatg gcatcgggct ggtaaacggc aaggtcgtag atgacggtgt
    30841 gccacagttt ggggtcgtcg tccacaaagg cggcggcgga atattcgcgc atttgtttga
    30901 cggcctcgag aagctgtctg cccgcctgcc ccgcgccgta aatgatgacg gggatcatct
    30961 gttttttggg gtgttcggac aacagtccgc gcaaaaccat acgcgagccg gtcacggaaa
    31021 caaacagcag taagaaatag acaatcggca gggcgaggcg cagcctttct tcaaaaatca
    31081 atgtgttgag gaagaacaat acggcggagg cgaggctgcc tgccagcgcg gtggagagga
    31141 tgcggaagct gatgaagcgt gtaacggcac ggtagagccc cattctgacg aacaggccga
    31201 tggtcaacgg cgcggtcaat aggaaagact gccagttggt agggtcgaac cattcgttcg
    31261 agtagtcggc cttcaggctt tgggtaaacc aaaaggcaat gaaaatcatc agaaaatcgt
    31321 gtatgaggaa acagattttc ttgatgttgc gcggtagggc aagcagggtt tccagagtca
    31381 tatcgtgggg cggtatgtgc tttcaggcgg catatgccgt ctgaagggtt atcgtgtggc
    31441 ttcggtcaat acggcttcga tgtgttcttt gcagaacgcg atttcgccgt cggtcagcgt
    31501 cggatgtact aagaacatca ggctggtgtc gcccaactcg acagcatttt tcagccgctc
    31561 tttcggacgc caaggcgtgt tgtcgaagga tttctccaaa tacacttcgg agcagctacc
    31621 ttgatagcag gggactttgc gcgcgttcag ttcgttgacg atgcggtcgc gcgtccagcc
    31681 gtctttgagg tgttcgggtt tgacgaaggc gtagaactta tattgcgcgt gtccgatgta
    31741 gtcggcgact tcaaccaagc ggatactttt gaatttgcct aggctttccg ccagcttggc
    31801 ggcgtgcgct tgacggcagg cagtccattc gggcaggcgt ttgagctgaa tgcgcccgat
    31861 tgccgcctgc atttccatca tacgccagtt tgtgccgaag ctttcgtgca gccagcggaa
    31921 accgggcgcg tgttcgcggt ggtacacggc atcgtagctt ttgccgtggt ctttgtacga
    31981 ccacattttt tcccacaggg ttttgtcgtt ggtcgtaacc ataccgcctt cgccgccggt
    32041 ggtcatgatt ttgtcttggc agaacgacca cgcgccgacg tgtccgatag agccgacgga
    32101 tttgcctttg tattttgcgc cgtgcgcttg ggcgcagtct tcgattaccc aaagattatg
    32161 ttcttttgcc aaagccataa tgccgtccat ttcggcgggc ataccggcga ggtggacgac
    32221 gatgacggct ttggtattcg gggtcagcac agctttgacg gtttccgcgc tgatgttttg
    32281 gctgttcaaa tccacgtcgg caaacacggg atttgcgccc gcgttcacaa tgcaggaagc
    32341 ggaagccaag aaagtgcgcg aagtaacaat cacatcgtcg cctacgccta tgccgattgc
    32401 tttgagcgcg acatcgagtg ccagcgtgcc gttggaaagg gcgacggcgt atcgcgtgcc
    32461 agaaaaggcg gcaaattctt tttcaaattc gcggcattcg ctgcccgtcc agtaattgac
    32521 tttgttggac agcaggactt tggaaacggc atcggcttct tcttgggtga agcagggcca
    32581 cggggagagg gaggtgttca gcatgatggt ttgtccttcg ggttcggacg gcatttccga
    32641 ccctatgccg tctgaagggg gtgtgttccg aagaatcggg cgcacgccgc aggtgttgtc
    32701 aaaatcggtc tgtacggggg tgtatagtgg attaaattta aaccagtacg gcgttgcctc
    32761 gccttgccgt actatttgta ctgtctgcgg cttcgtcgcc ttgtcctgat ttaaatttaa
    32821 tccactatat tttaatcgct tatgccgtcc cggtcttggg gtttttgcgc ggtagcggct
    32881 ttgccggatt gcccgcgacg gtcatgccgt ccgggatgtc gcacacgata accgcccccg
    32941 cgcccattca acttccatcg tttccaaatg gtgtcgaaaa cgtagggcgg aaagccgttt
    33001 acgccccatg aataatattt tgtcatgaaa tagtcctttt aatattgtga gtgcatgttt
    33061 gattatgtaa tggttaagta tttgaatcaa ttataggaac taaatcttga agggagttaa
    33121 cccaaaagtc gggatgatat tctgtgttaa aactttcagg ctggtggcgg tggatgttct
    33181 gtccggaggg aagcaatcct atggttatcc agcccaaagt gttcggcgcg ataaagtctt
    33241 tggaaatgtt gtcgccgata tagatgaagc agcctgcctt gtcggcatat ttgtcttgaa
    33301 gatggcggaa gcgtttgccg tcgggctttt ccgaagagca ggcttcagag atgaggatgt
    33361 cgtcaaacag ggaagacaga cccaaggctt ccagcttcag gcgttgggtc aggcttctgc
    33421 cgtcggtaat cagcgcgcgt gcggcgaagg gcgcggtcag ttcggacagg aaatccggcg
    33481 gagcatacgg agtcagcgtc gggcggtgca gccggtattg ccacaaaaga acctgttttt
    33541 ccgattcatt aaaaccacag tggcggcaca atttgtccag ccaatctttg ccgtcggggt
    33601 cgatgttgcg ccataggttg tctgaattcc aatcgggata cagtgcggca acggtatcga
    33661 tgaccgaacg gataccggag agcttgtatt cgtattccga atacagggta tcgtccaagt
    33721 cgaagacgat gacggtggtt tcaggattaa tcgttttcat gaaccaagac cttggcatcg
    33781 tagcgcaaca taatgaggtt gttttcccag tcgtctgaaa acgggatttc ttcgtcgccg
    33841 aggtattcgc gcatcaaccg gctcggataa ttgccgcctg cggcatacgt cagcgggaag
    33901 ccaccgccga agcgggggtt gatttccacg ccgtagaatt cgccggtttc ttcgttgtag
    33961 aagaactgcg ccgtgataca gccgcgcgcg ccctgcaata ccgccatttt ttccagcagc
    34021 gtttggtaga ggctgttttt gcaggtaacg cctttgctga tttcgccgga gcgcacttcc
    34081 aagcgttttc gcgggatggc gcatttcaga cggcattgac ggtcgtaata catatcgacg
    34141 gtaaactcgg aaaatttatt ttcgatgtcg ataaactgac agaacattaa tttggtgtct
    34201 gccaagactt ccggtgtcag gtcggcaggt gtgtcaatcc gttttgcacc gatggcgcgg
    34261 ctgccgtcat aaggcttggc gaagcaaggg aaaaccaact tcttgcggtc gtaaatttcg
    34321 ggtgagcgta tgccgtagcg ggcaaacaag gtggcggttt tccgtttgtc gcggcattgt
    34381 gcgatgaagt ccgaatcgga aacgacgatg tggacacttg ccgcttcaaa gcgttcgcgc
    34441 tcgtctgcca gcttttgcag ttcggtgtct atggttggga tgattaaacc gatattttcg
    34501 cgtaccgcca gattgaaaat gctgtcgata tatgaatcgg tactaatcgg cggcacttca
    34561 aatgaaccgt ccgaaacatg gcaggcagaa gacatgcggg ggttgaggtc agtggcaaaa
    34621 acgctgatgc cgtctgaaaa acgtgcggct tcggtttgga agtcctgcac caattcgaca
    34681 cggcgacctg ccgacagaat cagtatatta tttttttcat tagtttgatt tccagtgaaa
    34741 taaggcatag tggcttcccc ttccgccgaa atcccttctt tgataaagac ttttctgact
    34801 gtcaaaaaca ggattttcat atccagccaa aaactgtaat ggtcgatata ccaaacatcg
    34861 caggcgaatt tttcgtccca cgaaagcgcg ttgcgcccgt tgacctgcgc ccagccggta
    34921 atgccgggtt tcatttcgtg gcggcggttt tggaagttgt cgtacagcgg cagatattgc
    34981 atcagcagcg ggcgcgggcc gaccaggctc atgtcgcctt ttaagacatt ccataattca
    35041 ggcagttcgt ccaaactagc ggcacgcagt tttttgccga agggtgtgag ccgctcgctg
    35101 tcgggcagcg gaatgccgtc tgaatcaagc gcgtcgcgca tggaacggaa tttgaccatt
    35161 ttaaaaggtt ttccgtcctt tccggggcgt tcttgaatga agaagacggg cgaacccaga
    35221 ttcttgcgga tgaggtacgc caaaatcagg aaaacgggtg agaggacaat cagccccgat
    35281 gcggatgcga tgatgtcgaa caggcgtttg acggctttac tcatttgcca atctttcaat
    35341 caggttgacg attttccgat aggaaatgtc gcgcctgaag cggcggacga tttcatcgga
    35401 ctgaacgggg tcgtttttgc gtttcaaaat atctttggcg gcttgaacga agctgtccac
    35461 gtcgccggaa cggtagtttt cgtgcggcag caggttcaag aggctaagga cttcggcatt
    35521 ggtctggctg ttcagaatcg gtttttgcaa agccatatag tcggagagtt tgttggtaac
    35581 cgactgcatg gcgtggctat ggatggcgtt gacggcaatg tcgcagcctt tggcaatcga
    35641 catcatttca gaatagggta aataaccgta aaacttgatg gcgcgatttt catattgttt
    35701 gagtttctcc aaatcgggtc ctccgcccat aatgtgcaat tcgacgtttt cgccgtcgtc
    35761 taaaagtttc cgaacacctt tgcacacggt ttccacgtcg tagctgtaac tgagcgttcc
    35821 caagtagaaa aggcgggtgg ttttggagcg gaatcgcggg gggggggcga tggcggcaaa
    35881 atccgtaccg atatagacgg cttcgccggg tacgttcgga ttggcttctt tggcgcggtc
    35941 gagataagtc tgcgatacgg caaccagcgc gtcggcgcag cggtaggcac ggttggcgcg
    36001 tgaagcaaag ggcagcagct tgtgcggtac ttttttcaaa aatggtacga ccgaggagaa
    36061 agactccggc catacgtcct gcacgtcgac aatcagtttg tagcccaaac gcgctttgtg
    36121 tttgcccaac agcaggttgg tcgccatcag cggataggca gaatagacga tgtcctgttc
    36181 cgccgcctgc gggctgtgca gccagcgtgc caaattgcgg acgaatacgc ggtggctggc
    36241 gacgcgggcg agggagacgt tttttcggta gccaggttcg tccagcagct tgacgcgcag
    36301 cctgccgttt gaagtggcgg cagcatcttc atgccgtctg aaggatttgt cgtagtggcg
    36361 gaaacggctg gtaatcagca acacgtcgtg cgattgcgac aatcgttctg ccagatacca
    36421 aaagcggttg aaatacggtt cggacggcag cgagcagtag ggggcgacta tggtgatgtt
    36481 catcggcggc tttcagacgg cattacatgg tatacgccgc catggtggtg cggtagattt
    36541 cgtcgtcgga acagagtgcg gcgacgtgtg cgtgcagcct tttgcccatt gcttcgcgca
    36601 actccggttg tctgacgagc gtgtctacgg cggcgataaa ggcttcttcg tcgccgaagg
    36661 ggatgcagta acccgtttcc ccgttgacga ccatttcgga aatgcccgcc atatcgtagg
    36721 taacgacggg cgtgtcgtaa agtccggctt ctaagatgtt gttgcctaca cctgcgccgt
    36781 ggtcgccgat gcagtggggc gtgttcacca aaatatccac gtctttgaag taggcggtca
    36841 aatcgcgtat gccgccgagg aaggtaactt tgccgtctat gcccagacgt tccgcctgcg
    36901 ctttcaaatt gtccatttct tcgcctatgc ccgccacgtt caggcgtacg ggcatatcgc
    36961 ggtcgaccat ttttttgaaa atgtccagca tcagatgcac ggcgcggacg gtgtccaggc
    37021 gcgacagcgt gccgagcatg acgcagcctt tgacggtttt ccagaaagga aattccgggg
    37081 ggggggggag tgcgttgtag gcgtagacaa tccggtcggc ggggaaaccg tggcggatga
    37141 gtttttcgcg ttcgtgtttg cagttaccga tgatgtacac gcccagcttg tcgaagagct
    37201 tggcgatttt ggggtaggtt gccgcgtcca aaccgtgcga gtggtagatg attttggttt
    37261 tcggcgaaac gattttggcg gcaatggcgc aggcgggtac gacgcgcgcc atttggcagt
    37321 cgatgatgtc gggttgttcg cgccgcagca ttcgggcgta ggcaatcata cctttgaggt
    37381 agccgaaaag gccgccgcga tagaaatcga cgggttgcca acggatgccc gatgcttgcg
    37441 cctctccgac aaaaggcccg tccgaagaag caaggatgat gtcgtgcccg cgccgtttga
    37501 gcagccgccc gaggcggacg gtggcggttt ccgtgccgcc caagcccgac atagaagtgg
    37561 tcaggatgat tttcataatg gaaacccttg ttttttcaaa taatgaaaca gtttgtgcaa
    37621 atctttccgg tggcgcagga tgcagcctgc cagatatacc gcccatacgc cggcaaacag
    37681 ggggtagttt gccggtgtgc cgaagcaggt gtaggccgcc gaggaggtca ggcagagcaa
    37741 tgtgtgcgta taaagcggca ggcgtttgag cggctgccac aggcgacagg agctttctgt
    37801 cttgaaaaca aaaaacaacc agaatgaggc ggcacaggca accgccgcgc cgcgcgcgcc
    37861 gccggacggc acggcaagcc ccagcagcag caggtttgcc gccagcgcgc ccaaggtggc
    37921 gagcgcgatc gggcgcgttt tgcggacgac gttcaaaccg atgccgctga tttccgccag
    37981 cgtgcaaaac agcggcggca gcatacacga tacgacgata aaccggacgg cggcgtagtt
    38041 ttccggcagc aggagggagg caaggggcga gaaaatgccg gtcaggcaga gggcggaggc
    38101 aagcagggcg gcggcggatt ctgccgttgc cgagagacgg gcgggcgggg cgttttcttc
    38161 gattgcgcgg aaaatatacg gtgtccagac cgttgaaaag atgctttgga acaataatgc
    38221 cgccccgccg aacgaaatac ccatcgaata aacgccgagc tgttctaggc cggcatattt
    38281 tttcaggaac aaacggtcgg cggatgccag cccccaatag gcgatgctgc ttagtgcgat
    38341 cggtatgccg tagcgcaggc cgcgatgcag gacggcggat gaaaacggtg cgcgccggac
    38401 ggccttcaga cggcatcggt tttgaaacag caaaaaggcg gcggcggcaa ggtttgccag
    38461 cgcgtaaacg gcggtcagga cggcggtgtt cgccggaaag tgcagcagcc cgaccgtcag
    38521 cggcagcagc agcaggatgg cgagcttgga cacgagttgc gcggacgaaa aggcaagggc
    38581 gcgtccttcc atacgcaaaa ccagtaagag aaagcggatg ggcaggaagc tcagttcaaa
    38641 cagcaccagc ccgatgccgg cggcggcatc gtcgagcgaa aacaggattt cagacggcag
    38701 ggatgggcgg gaaagcagca gggcggctat cgcggcggca gacagcagcg gcggcaggaa
    38761 cagggttttg aacaaagtgt ctttgtcggc ggcggcatag tattcgcgga cgtatgcctg
    38821 atccagcccg aggcacaata ccgacaccgt cagtcccgcc gccgtctgca tcagcacgat
    38881 gcgcccgatg tcgtcggcgg ggaaatacca cgacagcagc ggcaggatga tgacggctaa
    38941 aaccgcgctg ccgatcgagc ctgccgcgta gccgaggatt tcttttgtgt ccatttttga
    39001 tgtccgggcg gcggcgggat gctgcctgtg tcgtctgaag cctttcttga tcggaatttg
    39061 acggctttca gaccgtcgcg gctgccggcg gggtgcggca gtccgggtcg cgcttttccg
    39121 ggcgggcggc ggtctgaacg gggccgtttt ttatcggcgt tattatatag tgaaacggcg
    39181 caaacccttt aaaaggcgtt gccgtttttt cggaacacgg ttttgatgtc gtgtccgagg
    39241 atttcgcttg aaacgggtgt ccacaagggc ggtgcggaaa gggcggcgcg gttttcgagc
    39301 agggaaaaca ggtctttgcc gctgccgagg attttgggcg aacggtacag gacgatttcg
    39361 tctgccagat tttctgccaa aaatgcggat gtgagttcgg agcctgcttc gaccatgatt
    39421 tctccgaaac cttcgtcggc aaggaggcgc atcagatggt tcaggtcgat tttgccgcct
    39481 gccgtttcag acggcatcag gatgcggacg tgggcgtgtt tgcgataggg gcggagtttg
    39541 tcttcatcgc gttccaaggt ggcgatgtag gttggagatt gtccgtcggt cagaaggtgg
    39601 ctgtccaagg gcaggcgcag gcggctgtct aacacgatgc gtgcgggttg gcgcaaagtt
    39661 ggaaaagcgc ggacgttgag ccggggattg tccgccaaca ccgtgccgat gccggtcagc
    39721 accgcgcagc tttcggcacg caaaacctgt acgtcggcac gcgcgtcttc gccggtaatc
    39781 caaaagctgc tgccgtctga aagggcggtt ttgccgtcca gcgaaacggc gcatttgagg
    39841 cggacgaagg ggcggcggcg ttcgatgcgc gacaggaagc ctcggttgag ttcccttgcc
    39901 tgatgttcga gtaaaccgca ttccgtcttg atgcctgctg cttcgagcag ggcaagccct
    39961 ttgcctgcaa ccagcgggtt ggggtcgcgc atggcggcga cgacgcgtgt tacaccggaa
    40021 cggagcagag cttcggcgca gggcggtgtg cgtccgtaat ggctgcacgg ttcgagggta
    40081 acaaaggcgg tcgcgccttg tgccatttcg cccgcctgac gcagggcgtg gacttcggcg
    40141 tgcggttcgc ccgctttgac gtggaagcct tgcccgacaa tttggctgcc gtgtgcgata
    40201 acgcagccga cgcgcggatt gggcgaagtg gaaaaacgtc ccaaagcggc aagtcggagg
    40261 gcggtttcca tcatggatat atctgtgtcc gaaaacatag ggataccgta tcagtatggg
    40321 ttggggagaa tcaggctttg cggtctgttt tgacggcttg cgccagccac gaggcaaagt
    40381 ctgccggatt gtcgaagcgt ttgtgcaggg cggcgaaacg gacggcggct tccgtgttgt
    40441 gctcaagcag ctcttttagc accatgtcgg caagtgcggc agaggggatg tcgcgctgac
    40501 ccgaagtgta gagcctgtgt ttcgtcaggc ggacggtttc gtcgatctgt tcgggtgtca
    40561 gggcggattt tcgggcggcg gcggtcaggt cgttgcggag gcgttgtgca ttaaagggcg
    40621 aacgtttttt gtccggaccg atgacggcgg gcattttgag ttcggcggtt tcgagcgtgc
    40681 cgaagcgttt gccgcagctg gggcagtggc ggcggcggcg cacggcgttg cgttcttcca
    40741 tcaggcgcga atcggcgacg cgggtgtcgg ggtgggcgca aaacgggcat ttcatagcgt
    40801 ttcttcctga tgccgtctga acgtcaaacc gatacgccgg cggcgcgggc gatttccaga
    40861 ccttcttcgg cactcatata gacggggttt tcgggacggt cgtgtcggac gatgttgcct
    40921 tcgcggaaca tgaccagttc gtccacggca agttgggacc atgattcgtc gcgggtcagt
    40981 ggcagggtgg cgataacggc gacgcggtcg gagggcgtgg ttacttcggc aaaatcgacc
    41041 atcacgtcgt cgtcgagcag gcgcgccttg ccgaacgggg cttggcggac gatgtagtgc
    41101 agcagtgtgc tggcgtgggc aaacagggca atgccgtctg aaagcataaa gttaaacagc
    41161 ccgaacttgc ggatttcgtg cgtcagcccc gcaatcgcgt caaacagcgt gtcgtcgtcg
    41221 ggacgggcgg caaagcgggt gcgcaggcgg ttgaggatgt ggcagaacgc gcgttcggaa
    41281 tcggttgtgc cgacggggtg gaaaaattcg ccctgttcgg ggaaaaaatt aatcaaatgt
    41341 ccgttgtggg caaacagcca gtagccgccc cacatttcgc gcataaaggg atgggtgttc
    41401 gccagcgagg tttgtccttg tgatgctttg cggatatggg cgacgacgtt ttccgattta
    41461 atctggtagg cgcgcacgag gtcggcgacg ggcgaattgg cactgggttt gtcgtcatgg
    41521 aacaggcgca cgcctttgcc ttcgaaaaag ccgatgccga aaccgtcggc atggtggtcg
    41581 gtaatgccgc ccctgcggcg gaagccttca aaggaaaaca taatatcggt cggcgtattg
    41641 cagttcatgc ccagcagttg acacatggtt tgtcccaatg attcagatgg tcgcaagtat
    41701 tcggattata ccccgaactg aaaatgccgt ctgaaatacg gcttgttccc cattattccc
    41761 tcgaaaacag aaaacaaaga cggaaactta agattccgtc attcccgcgc aggcgggaat
    41821 ccgacttgtc cggttttggt tgtttttcgt tccgtaactt tt
//
LOCUS       DAXIDM010000004        40783 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000004 DAXIDM010000000
VERSION     DAXIDM010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 40783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40783
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.004"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(44..631)
                     /locus_tag="ACFOAE_000138"
     CDS             complement(44..631)
                     /locus_tag="ACFOAE_000138"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC6883715.1"
                     /translation="MVWKTLGEVFDLKNGYTPSKSNKEYWENGSIPWFRMEDIRENGR
                     ILDNSLQHISKSAVKGGKLFPANSIIMATSATIGEHALITVPFLANQRFTSLSLKPEF
                     ADKLSIYFLYYYCFNLSEWCKKNTTTSSFASVDMNGFKRFPIPIPPLPEQEKIVAILD
                     KFDTLTHSISEGLPHEIALRRKQYEYYREQLLAFR"
     gene            complement(657..1253)
                     /locus_tag="ACFOAE_000139"
     CDS             complement(657..1253)
                     /locus_tag="ACFOAE_000139"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFC6883716.1"
                     /translation="MDMQSKAKKLIEMIQTAPVEWKPLGGENGIAIIKTGQAVSKQKI
                     SNNIGSYPVINSGKEPLGYIDEWNTENDPIGITTRGAGVGSITWQEGRYFRGNLNYAV
                     TIKNRTELDVRFLYHILLEFEQEIHALCTFTGIPALNASNLKKLLIPIPPLETQQKIV
                     KILDKFTELEAELALRKRQYRYYRDFLLDFDNQIGGDS"
     gene            complement(1419..2429)
                     /gene="rhuM"
                     /locus_tag="ACFOAE_000140"
     CDS             complement(1419..2429)
                     /gene="rhuM"
                     /locus_tag="ACFOAE_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RhuM family protein"
                     /protein_id="HFC6883717.1"
                     /translation="MSIILYTANDGTAQFALQEFGGQLWLTQADMAELYQTTKQNISK
                     HIKTILAEQELEEKATVNFQLTVQNENGRKVNRKIAHYSLPMIIAVGYRVRSARGIQF
                     RQWATERLDEYLTKGFAIDDERLKGTGGGNYWKELLNRIRDIRSSEKALYRQVLDLYA
                     TSQDYNPKSSESQTFFAAVQNKLHYAASRQTAAELIYSRADSSKDFMGLTTFQGAIPT
                     LNEAKIAKNYLTEDELFRLNRLVSAFFDLAEIKAQEQSPMYMRDWIAELDKFSGLYGQ
                     GTLQGAGSISRKQAEQKAEREYRAYEARILSPVEQAYLESVKALEKTAVQQIKQKKDR
                     TK"
     gene            complement(2426..3970)
                     /locus_tag="ACFOAE_000141"
     CDS             complement(2426..3970)
                     /locus_tag="ACFOAE_000141"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFC6883718.1"
                     /translation="MMTEMQQRAQLHRQIWKIADEVRGAVDGWDFKQYVLGTLFYRFI
                     SENFTDYMQAGDSSIDYAAMPDSIITPEIKDDAVKVKGYFIYPGQLFCNIAAEAHQNE
                     ELNTKLKEIFTAIESSASGYPSEQDIKGLFDDFDTTSSRLGSTVADKNKRLAAVLKGV
                     AELDFGSFEDYHIDLFGDAYEYLISNYAANAGKSGGEFFTPQSVSKLIARLAVHGQEK
                     VNKIYDPACGSGSLLLQAKKQFDEHIIEEGFFGQEINHTTYNLARMNMFLHNVNYNKF
                     HIELGDTLTNPKLKDSKPFDAVVSNPPYSINWIGSGDPTLINDDRFAPAGVLAPKSKA
                     DFAFILHALNYLSGRGRAAIVSFPGIFYRGGAEQKIRQYLVEGNYVETVIALAPNLFY
                     GTGIAVNILVLSKHKDNTDIQFIDAGGFFKKETNNNVLTEEHIAEIVKLFADKADVPH
                     IAQNAAQQTVKDNGYNLAVSSYVEPEDTREIIDIKQLNAEISETVAKIERLRREIDEV
                     IAEIEA"
     gene            complement(4043..5047)
                     /gene="rfaD"
                     /locus_tag="ACFOAE_000142"
     CDS             complement(4043..5047)
                     /gene="rfaD"
                     /locus_tag="ACFOAE_000142"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008712 - ADP-glyceromanno-heptose
                     6-epimerase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HFC6883719.1"
                     /translation="MTIIVTGAAGFIGSNIVKALNQRGITDIVAVDNLSKGEKFKNLA
                     ECEIAHYLDKHEFIRQVREHILPYQNIEAVFHQGACSDTMNHDGLYMMENNYQYTLDL
                     LDWCQDERIPFLYASSAAVYGKGEIFREERELEKPLNVYGYSKFLFDQVLRRRMKERL
                     TAQVVGFRYFNVYGQHEQHKGRMASVAFHHFHQYREHGYVNLFGSNDGYGNGEQTRDF
                     VSVEDVAKVNLYFFDHPELSGIYNLGTGRSQQFNELAAATVNACRAAEGKPEMSLKEL
                     VEEEFIRYIPFPDALKGKYQSFTQADITKLREAGYTEEFFDVKAGVERYVKWMLENLA
                     "
     gene            complement(5088..6206)
                     /locus_tag="ACFOAE_000143"
     CDS             complement(5088..6206)
                     /locus_tag="ACFOAE_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFC6883720.1"
                     /translation="MPDFQRITIENIEYFIVDSIQNLRAEDSFIHRNNKLSVFGGNGE
                     ARKYVGSYIDDSGRKLSTFFEYENWGITETKNGRRVEYPLIQKNCFFNKKNLQRYLVD
                     AKVEYHKQEQKYHHDISRFYDDYVLSINNLPTENIFFSIHDVSDHLENSKGYRRGYIR
                     SEDDIWSIWRKIVLPKISYLSILKLLPVKDIEDSEPLFYFRIFLDYQFRSIVHPQLLS
                     REKLEIPASEFNQFVEQEIIKQKSRKGQQKYRKDVINHMPQCPFTLITDEILLRASHI
                     KPYMVCITEKNEKEALDYLNGLALTPTYDWLFDQGYITFLDDGRLICGTRLSRYTWEK
                     LNINPNAKNKMRIYPEGREKYLEYHRKFVFQDNIDDFL"
     gene            complement(6208..7443)
                     /locus_tag="ACFOAE_000144"
     CDS             complement(6208..7443)
                     /locus_tag="ACFOAE_000144"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC6883721.1"
                     /translation="MTISTMAQTHDTRLQKTLLFPSQQGWKSKTFLKPDSHIRLATVF
                     SGIGAVEQAFHRLNLNHTIVFAGDIDPYVKKSYLGNYKLNEDFWHNDITQFDARKFRN
                     QVDILVGGSPCQAFSMVGKRAGLEDTRGTLFYEFARVVDEVQPKIFIYENVKGLLNHD
                     NGKTWKVVKSVFYSLGYDLYFQIMNSKDYGIPQHRERIFVVGFHTPPINGFQFPEKIE
                     LEHTMQDFLEDYTDSKYFLREKGVKFVTSSKNRQKRYTQINGEIALCQKANQQFNWHG
                     DFIFQAARESEFDDFIFDVNNVEEKYYLSEKIKNYVLAGGTKNFKTSTETDLPVARPL
                     LQTMHKMHRAGVDNYVTHNRGRIRKLTPRECLRLMGFRDDFKILVSDTQMYRQAGNSI
                     VVDVLIAILKQMDITLYGE"
     gene            complement(7480..8451)
                     /gene="hldA"
                     /locus_tag="ACFOAE_000145"
     CDS             complement(7480..8451)
                     /gene="hldA"
                     /locus_tag="ACFOAE_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose synthase"
                     /protein_id="HFC6883722.1"
                     /translation="MSAKFQQETLKSRFAQAKVLVVGDVMLDRYWFGDVSRISPEAPV
                     PVAKIGRIDQRAGGAANVARNIASLGGRAGLLSVTGNDEAADALDALMVQDGVASYLM
                     RDKQIATTVKLRVVARNQQLIRLDFEEHPNCEVLEQIKQKYREILPEYDAIIFSDYGK
                     GGLSHISDMIDWAKHAGKTVLIDPKGDDYEKYVGATLITPNRAELKEVVGSWKNESEL
                     TEKAQNLRRHLDLTAVLLTRSEEGMTLFSEGEPIYQPTRAQEVYDVSGAGDTVIAGMG
                     LGLAAGCTMPEAMYLANTAAGVVVAKLGTAVCSFAELIKALSGQSTM"
     gene            complement(8506..9246)
                     /gene="pyrF"
                     /locus_tag="ACFOAE_000146"
     CDS             complement(8506..9246)
                     /gene="pyrF"
                     /locus_tag="ACFOAE_000146"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFC6883723.1"
                     /translation="MNPLISDFQTPQQRTPVIVALDFSNEKDTLGFVRNLDPTLCQIK
                     IGKELFTATGRNLAESLINQGFKLFLDLKYHDIPHTVAQACKVAADMGVWMVDMHASG
                     GRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNTAPEEQVIRLAKLAQSS
                     GLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAASTYL
                     VMGRPVTQAADPVAVLREVNRVANLEAN"
     gene            complement(9772..10419)
                     /gene="adk"
                     /locus_tag="ACFOAE_000147"
     CDS             complement(9772..10419)
                     /gene="adk"
                     /locus_tag="ACFOAE_000147"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004017 - adenylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFC6883724.1"
                     /translation="MKALFLGAPGAGKGTQAQFITAAFGIPQISTGDMLRAAIKAGTP
                     LGLEAKKIIDEGGLVRDDIIIGMVKERIAQDDCKNGFLFDGFPRTLAQAEAMVEAGVD
                     LDAVVEIDVPDSVIVDRMSGRRVHLASGRTYHVTYNPPKVEGKDDVTGEDLIQRDDDK
                     EETVKKRLAVYHEQTEVLVDFYSKLEGEHAPKYIKVDGTQPVEAVKAEVLGALGK"
     gene            10634..11473
                     /gene="htpX"
                     /locus_tag="ACFOAE_000148"
     CDS             10634..11473
                     /gene="htpX"
                     /locus_tag="ACFOAE_000148"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HFC6883725.1"
                     /translation="MKRIFLFLATNIAVLVVINIVLAVLGINSRGGTGSLLAYSAVVG
                     FTGSIISLLMSKFIAKQSVGAEVIDTPRTEEEAWLLNTVEAQARQWNLKTPEVAIYHS
                     PEPNAFATGASRNSSLIAVSTGLLDHMTRDEVEAVLAHEMAHVGNGDMVTLTLIQGVV
                     NTFVVFLSRIIANLIARNNDGSQSQGTYFLVSMVFQILFGFLASLIVMWFSRQREYRA
                     DAGAAKLVGAPKMISALQRLKGNPVDLPEEMNAMGIAGDTRDSLLSTHPSLDNRIARL
                     KSL"
     gene            complement(11774..12439)
                     /locus_tag="ACFOAE_000149"
     CDS             complement(11774..12439)
                     /locus_tag="ACFOAE_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883726.1"
                     /translation="MENIEEYALLSPEALLERLDTVLSIRIGGKGWESSMTANFAQTL
                     VEIQDSLYRVVSTVQYGDDNLKRLTADKRKQYELNFKISEGSTRVESDFKETLVRFGR
                     DMLQDMPPKIRSATLVALTTLLVGGALGYGYLEYLKQVASEGYQTERLYNAVDRLAES
                     QERITSAILKGARGADFVQIGRRSYSREDISEANRRAERVPYGAELVSDGNFTAVLSD
                     IGD"
     gene            complement(12447..12839)
                     /locus_tag="ACFOAE_000150"
     CDS             complement(12447..12839)
                     /locus_tag="ACFOAE_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6883727.1"
                     /translation="MGKRMTFDTAKSRFQEKFPHLELLEFSGIYKPSSVRCPTHGVVQ
                     LLYYDTAIKSKYGCPECGKLKMKENTPPQNQKPVSILDTATGETLTFPSVQAAAKALN
                     IPYGSIRTKLDGRSNPDNLVCNRYKVLL"
     gene            complement(13047..13439)
                     /locus_tag="ACFOAE_000151"
     CDS             complement(13047..13439)
                     /locus_tag="ACFOAE_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6883728.1"
                     /translation="MAKSFNQAASELTDIFPNISLTGFDGVNYPVTVNCPMHGNVRYS
                     TFNALIKSKYGCPECAKMSKTQTPPNVGKPLLILDTTTNETLTFPSVTAAGAALGVHF
                     QQINHRLKGRTSPDNLISNRYKVLGYDR"
     gene            complement(13556..13966)
                     /locus_tag="ACFOAE_000152"
     CDS             complement(13556..13966)
                     /locus_tag="ACFOAE_000152"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6883729.1"
                     /translation="MALTFTQAVSKLTSKFPHLNLVEFNGVRYPTVIVCPIHGRVTCS
                     TFKSMLDSKSGCPKCASYGVNSHKIPEDTIDKLSKNTVLEDTVTGETLTFPSRASAAR
                     SLGINPAAITDRIKGRVHTETLLAGRYKVHICTK"
     gene            complement(13980..14363)
                     /locus_tag="ACFOAE_000153"
     CDS             complement(13980..14363)
                     /locus_tag="ACFOAE_000153"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6883730.1"
                     /translation="MPKSLSLQDVQLRFSSKFPDKTVLKFTKNYEPVTIQCPLHGSVV
                     YGNLQAAMKSSTGCPECTRNPEKPSPNAVAIRLEDTETGEIYEFASTLAASKFIGCSN
                     STLAVRLSGRTPFDRLIRYRYRLVK"
     gene            complement(14828..16126)
                     /locus_tag="ACFOAE_000154"
     CDS             complement(14828..16126)
                     /locus_tag="ACFOAE_000154"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFC6883731.1"
                     /translation="MAKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTL
                     VVGGKKTILRLIPSGILHESLDCFIGSGVVVSPEALLGEIDELNAAGVKNVEGRLKIA
                     PTCPLILPYHIALDQAREASRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEKLR
                     EKLDAILAYYNVQLQHLHNAEPVKAEDVMAVIEKVALRIAPMITDVSRVLNEKNKNGE
                     KLLFEGAQGALLDIDYGTYPFVTSSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVG
                     SGPFPTELFDEVGAGLAERGHEFGSVTGRARRCGWFDAAALKRSIQINGISGMCITKL
                     DVMDGVETINICVGYELPDGGKTDILPCGSDAVETCKPIYETMEGWKESTFGIKNYEE
                     LPDNAKAYLKRIEEVCGAPVAIVSTGPDREETIVLHHPFA"
     gene            complement(16230..17381)
                     /locus_tag="ACFOAE_000155"
     CDS             complement(16230..17381)
                     /locus_tag="ACFOAE_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HFC6883732.1"
                     /translation="MQTWQLPEHIADVLPTNARQLESAREQLLALFRVHGYELVQPPL
                     MEYAHSLLTHIDAGLSLKTILVTDRLSGRQLGIRADITPQVARIDAHLLSANQGINRL
                     CYAGPVLHAQPDGLLNMREPLQAGAEMYGFADIRGDIELIDLMLKSMKIADMGKVLLS
                     LGHIGIFRALSDAAHLDAGQSATLLALMQDKDTGAVEAQVKAWKLDGMWAKAFSLLPR
                     LYGGREVLSDARGRLPDLSAVGGALDELQAVCDAFPDCEIHIDLSELRVDNYHTGLLY
                     AAYAADFHDAVARGGRYDGLGGYFGRARPATGFSFDLRSFIGRLPAIERQPAVLVDAE
                     DAEAAREAVEALREQGQCVVVDYGIGHNVSEELAGRLKKTDGVWQVVKR"
     gene            17716..19095
                     /gene="norM"
                     /locus_tag="ACFOAE_000156"
     CDS             17716..19095
                     /gene="norM"
                     /locus_tag="ACFOAE_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter NorM"
                     /protein_id="HFC6883733.1"
                     /translation="MLLDLNRFSFSVFLKEVRLLTALALPMLLAQVAQVGIGFVDTVM
                     AGGAGKEDLAAVALGSSAFATVYITFMGIMAALNPMIAQLYGAGKTDEVGETGRQGIW
                     FGLFLGVFGMVLMWAAITPFRNWLTLSDYVEGTMAQYMLFTSLAMPAAMVHRALHAYA
                     SSLNRPRLIMLVSFAAFVLNVPLNYIFVYGKFGMPALGGAGCGLATMAVFWFSSLALW
                     IYIAKEKFFRPFGLTAKFGKPDWAVFKQIWKIGAPIGLSYFLEASAFSFIVFLIAPFG
                     EDYVAAQQVGISLSGILYMIPQSVGSAGTVRIGFSLGRREFSRARYISGVSLVLGWML
                     AVITVLSLVLFRSPLVSMYNNDPAVLSIAATVLLFAGLFQPADFTQCIASYALRGYKV
                     TKVPMFIHAAAFWGCGLLPGYLLAYRFDMGIYGFWTALIASLTIAAVALVWCLELCSR
                     EMVRSHKVV"
     gene            19139..20179
                     /gene="murB"
                     /locus_tag="ACFOAE_000157"
     CDS             19139..20179
                     /gene="murB"
                     /locus_tag="ACFOAE_000157"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFC6883734.1"
                     /translation="MQPIRYRTDLTPYNTFGLRAQARAFIALEHADELCDIVRLPEFD
                     RDTVLWLGGGSNILLMQDYAGLVVHMENKGIREIARSDGIVRIEAQAGEIWHDFVLHA
                     VALGLNGLENLSLIPGTVGASPVQNIGAYGVEAKDVIHSVRCFDLDTETFVELANADC
                     RFAYRESLFKQEGKGRYVIVSVVFALKTHFVPNLGYGDLAAAVAELSAGRVPTAKDVS
                     DAVCAIRNSKLPNPNVLGNVGSFFKNPVVSAEKAATLLQRHPDMPRYPQPDGSVKLAA
                     GWLIDQCRLKGFQIGGAAVHDRQALVLVNKNNASANDVRQLAQHIKFTVFARFQVELH
                     AEPNWLPASFSL"
     gene            20191..20841
                     /locus_tag="ACFOAE_000158"
     CDS             20191..20841
                     /locus_tag="ACFOAE_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFC6883735.1"
                     /translation="MPVTRPAKINTYTRIIDASLALFNEEGERNISTNHIAAHLGISP
                     GNLYYHFRNKDEIIVQLFKRYSEALLEYLNEAVLPSDVEDSINYMAGIYDVMWEYRFL
                     FSDVNTLLARSAELLGEHNTFTQAKVSPLLVNLLTQLNGLNIIQADQTAMNDLAVNMW
                     MITKYWFDFDSSLRGRTKLTEDSKARGIRRTLSLLRPYLLPEHREKYDRKIGNGNP"
     gene            20896..21672
                     /locus_tag="ACFOAE_000159"
     CDS             20896..21672
                     /locus_tag="ACFOAE_000159"
                     /EC_number="1.1.1.290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC6883736.1"
                     /translation="MRAVPPPHISITGLGYLGLPLAQKFYQHGSRVAAIKRSLTSDDI
                     NLPIHLDTFDLGSTDAFQTALWRHHADKPVWFFLLPPSSLTHYADTVKQWAELARACN
                     VQHLIFTSSTSVYGDTARECDEIALPDPQTESARQILAAEQHLLDSGISNIDILRLGG
                     LYCAERHPVSRLVQKQNIPGGNRPINIVHRNIAVESLFQTAFNPGGRRLKNIIEPRHP
                     TRREFYTEEAAKLGLPAPDFAPDDSVGKIIRTVCDNGLSL"
     gene            21723..22289
                     /locus_tag="ACFOAE_000160"
     CDS             21723..22289
                     /locus_tag="ACFOAE_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0032934 - sterol binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HFC6883737.1"
                     /translation="MSALLPIINRLILQSPDSRSELAAFAGKTLTLNIAGLKLAGRIT
                     EDGLLSAGNGFADTEITFRNSAVQKILQGGEPGAGDIGLEGDLILGIAVLSLLGSLRS
                     RASDELARIFGTQADIGSRAADIGHGIKQIGRNIAEQIGRFSREPESANIGNEALADC
                     LDEISRLRDGVERLNERLDRLERDIWID"
     gene            22309..23199
                     /locus_tag="ACFOAE_000161"
     CDS             22309..23199
                     /locus_tag="ACFOAE_000161"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HFC6883738.1"
                     /translation="MNSPFHNIGIVTRPNTPDIQDTAHTLITFLKQHGFTVYLDEVGI
                     KEGCIYTQDTVGCHIVNKTELGQYCDLVAVLGGDGTFLSVAREIALRAVPIIGINQGH
                     LGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIREGKTAERAIALNDAVLSRGG
                     AGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPIMQAGLHAFTLVPICP
                     QSMTNRPIAIPDTSEIEILVTQGGDARVHFDGQTHIDVQNLDRITIRRYRNPLRILHP
                     TDYQYFKTLRQKLHWGEQLV"
     gene            23224..23982
                     /locus_tag="ACFOAE_000162"
     CDS             23224..23982
                     /locus_tag="ACFOAE_000162"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFC6883739.1"
                     /translation="MNPKTPPDHTEDAVRLSKRMAQLGLCSRREADGYIEQGWVTVNG
                     KTAVLGQKVSPADRIELNKKAHEQQAARITILLNKPVGYVSAQAEKGYKSAAELITPE
                     NHWEGDTGRIRFDPKHKIGLAPAGRLDIDSVGLLVLTQDGRIAKQLIGENSGSEKEYL
                     VRVRGKLDEKGLALLNHGLSLDGEKLRPAQVEWQNEDQLRFVLKQGKKRQIRRMCELV
                     GLRVVGLKRIRMGKVKLGRLPPGKWRYLAPGESF"
     gene            complement(24037..24702)
                     /locus_tag="ACFOAE_000163"
     CDS             complement(24037..24702)
                     /locus_tag="ACFOAE_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFC6883740.1"
                     /translation="MTVLDREQVLSAFKNRKSCRHYDAARKISAEDFQFILELGRLSP
                     SSVGSEPWQFVVVQNPEIRQAIKPFSWGMADALDTASHLVVFLAKKNARFDSPFMLES
                     LKRRGVTEPDAMAKSLARYQAFQADDIKILDDSRALFDWCCRQTYIALGNMMTGAAMA
                     GIDSCPVEGFNYADMERVLSGQFGLFDAAEWGVSVAATFGYRVQEIATKARRPLEETV
                     IWA"
     gene            complement(24816..25589)
                     /gene="folE2"
                     /locus_tag="ACFOAE_000164"
     CDS             complement(24816..25589)
                     /gene="folE2"
                     /locus_tag="ACFOAE_000164"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003933 - GTP cyclohydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase FolE2"
                     /protein_id="HFC6883741.1"
                     /translation="MNTIADVQSSRDLRNLPINQVGIKDLRFPITLQTAEGIQSTIAR
                     LTMTVYLPAEQKGTHMSRFVALMEQHAEALDFAQLRKLTTEMVALLDSRAGKISVSFP
                     FFRKKTAPVSGIRSLLDYDVCLTGEIKDGAYGHSMKVMIPVTSLCPCSKEISQYGAHN
                     QRSHVTVSLTADAEVGIEEVIDYVEAQASCQLYGLLKRPDEKYVTEKAYENPKFVEDM
                     VRDVATSLIADKRIKSFVVESENFESIHNHSAYAYIAYP"
     gene            25781..26938
                     /locus_tag="ACFOAE_000165"
     CDS             25781..26938
                     /locus_tag="ACFOAE_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aspartate aminotransferase family
                     protein"
                     /protein_id="HFC6883742.1"
                     /translation="MKFATKAIHSSYDCDEHNRALMPPIYQNSMFALHEIGENVPYRY
                     SRLSNPTRQILEDTVADLEHGAAGFAFSSGMAGIDAVWRTFLRPGDTIVAVADIYGGA
                     YDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHKVKLVWLETPSNPLLRLVDIKVLAA
                     KAKAAGALVGIDNTFATPYLQQPLDMGCDFVFHSATKYLCGHSDVLMGIVVAKTKELA
                     QPLHDMMVHTGAVAGPLDCWLVLRGIKTLALRMNAHCQNALEIARRLEAHPAIEKVFH
                     PGLPSHEHYELAKTQMPKGIGGVVTVYLKNDTREAANSVIKNMKLVKMASSLGGVESL
                     VNHCYSQSHSGVPHDVKMEMGIKVGLLRFSIGIEDADDIWNDISAALDTTL"
     gene            complement(27001..28002)
                     /gene="hemB"
                     /locus_tag="ACFOAE_000166"
     CDS             complement(27001..28002)
                     /gene="hemB"
                     /locus_tag="ACFOAE_000166"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HFC6883743.1"
                     /translation="MQFPYRNVPASRMRRMRRDDFSRRLMREHTLTADDLIYPVFVLE
                     GSAREEDVPSMPGVKRQSLDRLLFTAEEAVKLGIPMLALFPVVTANKTERAQEAYNPE
                     GLVPSTVRALRERFPELGIMTDVALDPYTVHGQDGLTDENGYVMNDETVEVLVKQALC
                     HAEAGAQVVAPSDMMDGRIGAIREALEDAGHIHTRIMAYSAKYASAFYGPFRDAVGSS
                     GNLGKADKKTYQMDPANTDEALHEVALDIQEGADMVMVKPGLPYLDVVRRVKDEFGVP
                     TYAYQVSGEYAMLQAAVANGWLDGDKVVLESLLAFKRAGADGILTYYAIEAAKMLKR"
     gene            complement(28185..28469)
                     /gene="yhbY"
                     /locus_tag="ACFOAE_000167"
     CDS             complement(28185..28469)
                     /gene="yhbY"
                     /locus_tag="ACFOAE_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFC6883744.1"
                     /translation="MTDTKLNTKEILELKARAHHLHPVVMVGQQGLTDAVIKETDAAL
                     TAHELIKVRVFGDDRAERIEICTALCEAVDAQPVQHIGKLLVLWRKNIEG"
     gene            28579..29199
                     /locus_tag="ACFOAE_000168"
     CDS             28579..29199
                     /locus_tag="ACFOAE_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RlmE family RNA methyltransferase"
                     /protein_id="HFC6883745.1"
                     /translation="MAVRSKSSKAWLHEHVNDHYVHMAQKDGYRARAAYKLLEINEKD
                     KLIKPGTVLADLGSAPGSWSQVAAKLTGTSGAVFALDILPMEAIGGVSFIQGDFREND
                     VLAQFETLLDNRPLDLVICDMAPNMSGNAVSDQARSFYLCELALDFASQHLKTGGSFL
                     VKVFQGAGYQEYMAAMREIFGTVQTRKPEASRNRSSEIYLLGKNKR"
     gene            29263..31230
                     /gene="ftsH"
                     /locus_tag="ACFOAE_000169"
     CDS             29263..31230
                     /gene="ftsH"
                     /locus_tag="ACFOAE_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFC6883746.1"
                     /translation="MGNTFKSILVWVALGIGLMAAFNALDGKKEDNGQIEYSQFIQQV
                     NNGEVSGVNIEGSVVSGYLIKGERTDKSTFFTNAPLDDNLIKTLLDKNVRVKVTPEEK
                     PSALAALFYSLLPVLLLIGAWFYFMRMQTGGGGKGGAFSFGKSRARLLDKDANKVTFA
                     DVAGCDEAKEEVQEIVDYLKAPNRYQSLGGRVPRGILLAGSPGTGKTLLAKAIAGEAG
                     VPFFSISGSDFVEMFVGVGASRVRDMFEQAKKNAPCIIFIDEIDAVGRQRGAGLGGGN
                     DEREQTLNQLLVEMDGFESNQTVIVIAATNRPDVLDPALQRPGRFDRQVVVPLPDIRG
                     REQILNVHSKKVPLDKSVDLLSLARGTPGFSGADLANLVNEAALFAGRRNKVKVDQSD
                     FEDAKDKIYMGPERRSMVMHEDEKRATAYHESGHAIVAESLPFTDPVHKVTIMPRGRA
                     LGLTWQLPERDRISMYKDQMLSQLSILFGGRIAEDIFVGRISTGASNDFERATQMARE
                     MVTRYGMSDKMGVMVYAENEGEVFLGRSVTRSQNISEKTQQDIDAEIRRILDEQYQIA
                     YKILDENRDKMETMCKALMEWETIDRDQVLEIMAGKQPSPPKDYSHNLRENADAAEDN
                     APHAPTREETEAPAPADTASTESEQQPENKA"
     gene            31452..31883
                     /locus_tag="ACFOAE_000170"
     CDS             31452..31883
                     /locus_tag="ACFOAE_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RatA family
                     toxin"
                     /protein_id="HFC6883747.1"
                     /translation="MKKVEKNILVLHGADKMFELVDKVEDYPHFLPWYSKTEVIGRSG
                     NELKARLFMDYMHVRQSFATHNRNIPGREIRMELLEGPFKTLRGTWKFIDLGDDMCKI
                     EFNLEYDFSNAVLSALISPVFNHLSTTLVEAFVKEADRRYA"
     gene            31876..32154
                     /locus_tag="ACFOAE_000171"
     CDS             31876..32154
                     /locus_tag="ACFOAE_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HFC6883748.1"
                     /translation="MLEIEIVYGLPDRQVLKTMQLAEGTTVRAAALQSGLDGIFEDLN
                     LHSAPLGIFGKAVKDDTPLRDGDRIEVYRPLLIDPKEARRKRVQNQEE"
     gene            32201..32779
                     /gene="pth"
                     /locus_tag="ACFOAE_000172"
     CDS             32201..32779
                     /gene="pth"
                     /locus_tag="ACFOAE_000172"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFC6883749.1"
                     /translation="MSNKIKMVVGLGNPGKEYEQTRHNAGFWFLDELAWKWKASFKEE
                     KKFFGEVARATLPDGDVWLLKPTTFMNRSGQAVAALAQFYKIKPEEILVVHDELDIPC
                     GRIKFKLGGGNGGHNGLKDIQARLGTADYYRLRLGIGHPGDRNLVVGYVLNKPSTEHR
                     RQIDDAVAKSLQAIPDILAGKWEEATRFLHSK"
     gene            32839..33045
                     /locus_tag="ACFOAE_000173"
     CDS             32839..33045
                     /locus_tag="ACFOAE_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dioxygenase"
                     /protein_id="HFC6883750.1"
                     /translation="MSELNRLIQTESVAVIEETLNFLLYECSIDDAPSAEEIAVWRDM
                     LAARGGKFLRLSKLCQTWLEEEQA"
     gene            33042..33404
                     /locus_tag="ACFOAE_000174"
     CDS             33042..33404
                     /locus_tag="ACFOAE_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFC6883751.1"
                     /translation="MNLPRNRFILLSALWFAGSIYSLLFKAAETAPPPFPHFDKVAHL
                     ALFFAQIWLLTKAFRTDNRPIPYRSLMVFALCFALFSECAQAWFTATRTGSLGDVLAD
                     LTGAALALFTARAACRPD"
     gene            33635..35050
                     /locus_tag="ACFOAE_000175"
     CDS             33635..35050
                     /locus_tag="ACFOAE_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HFC6883752.1"
                     /translation="MNLHAKDKTQHPENVELLSAQKPITDFKGLLTTIISAVVCFGIY
                     HILPYSPDANKGIALLIFVAALWFTEAVHITVTALMVPILAVVLGFPDMDIKKAMADF
                     SNPIIYIFFGGFALATALHMQRLDRKIAVSLLRLSRGNMKVAVLMLFLVTAFLSMWIS
                     NTATAAMMLPLAMGMLSHLDQEKEHKTYVFLLLGIAYCASIGGLGTLVGSPPNLIAAK
                     ALNLDFVGWMKLGLPMMLLILPLMLLSLYVILKPNLNERVEIKAESIPWTLHRVIALL
                     IFLATAAAWIFSSKIKTAFGISNPDTVIALSAAVAVVVFGVAQWKEVARNTDWGVLML
                     FGGGISLSTLLKTSGASEALGQQVAATFSGAPAFLVILIVAAFIIFLTEFTSNTASAA
                     LLVPIFSGIAMQMGLPEQVLVFVIGIGASCAFMLPVATPPNAIVFGTGLIKQREMMNV
                     GILLNILCVVLVALWAYAVLM"
     gene            35169..35678
                     /locus_tag="ACFOAE_000176"
     CDS             35169..35678
                     /locus_tag="ACFOAE_000176"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC6883753.1"
                     /translation="MIILHTNKGDIKIELDFDKAPVTAKNFEQYVKDGFYDGVIFHRV
                     IKGFMIQGGGMDENMNEKETRDPIQNEASNGLPNDKYTIAMARTSDPHSASAQFFINT
                     ADNAFLNFRSKELYGKTVVQDWGYAVFGKVVDGFDVVDAIEGVSTKRHGYHDDVPSEP
                     VVIIKAEAV"
     gene            35845..37227
                     /locus_tag="ACFOAE_000177"
     CDS             35845..37227
                     /locus_tag="ACFOAE_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFC6883754.1"
                     /translation="MASIARDIFKAYDIRGIVGKTLTDEAAYLIGKAIAAKAAEKGIT
                     RIALGRDGRLSGPELMEHIRRGFTDSGINVLNVGMVATPMLYFAAVNECGGSGVMITG
                     SHNPPDYNGFKMMLGGDTLAGEAIQELLSIIEKDGFAAAGKQGSVTEKDISGEYLKHI
                     TGHIKLKRPMKIAIDAGNGVGGAFAGKLYKGLGNEVTELFCEVDGNFPNHHPDPSKPK
                     NLQDLIVELKNGEAEIGLAFDGDADRLGVVTKDGNIIYPDRQLMLFAQDVLSRNPKAK
                     VIFDVKSTRLLAPWIKEHGGEPVMEKTGHSFIKSAMKKTGAPVAGEMSGHIFFKERWF
                     GFDDGLYAGARLLEILSASDNPSEVLNNLPQSISTPELNIALPEGSNGHQVIDELAAK
                     AEFEGATEIITIDGLRVEFPDGFGLMRASNTTPILVLRFEADTQEAIERIQNQFKAVI
                     ESNPNLIWPL"
     gene            complement(37247..38002)
                     /locus_tag="ACFOAE_000178"
     CDS             complement(37247..38002)
                     /locus_tag="ACFOAE_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFC6883755.1"
                     /translation="MIKIRNIHKTFGESTILRGINLDVGKGQVVVILGPSGSGKTTFL
                     RCLNALEMPEDGQIEFDNERPLKIDFSKKPSKHDILALRRKSGMVFQQYNLFPHKTAL
                     ENVMEGPVAVQGKPAAQAREEALKLLEKVGLGDKVDLYPYQLSGGQQQRVGIARALAI
                     QPELMLFDEPTSALDPELVQDVLNAMKELAREGWTMVVVTHEIKFALEVATTVVVMDG
                     GVIVEQGSPKELFDHPKHERTRRFLSQIQSTKI"
     gene            complement(38012..38728)
                     /locus_tag="ACFOAE_000179"
     CDS             complement(38012..38728)
                     /locus_tag="ACFOAE_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFC6883756.1"
                     /translation="MFNNFLASLPFMTETRADMIVSAFLPMVKAGFAVSLPLAAASFV
                     IGMVIAVAVALVRIMPAGGIARKILLKLVEFYISVIRGTPLLVQLVIVFYGLPSVGIY
                     IDPIPAAIIGFSLNVGAYASETIRAAILSVPKGQWEAGFSIGMTYMQTFRRIVAPQAF
                     RVAVPPLSNEFIGLFKNTSLAAVVTVTELFRVAQETANRTYDFLPVYIEAALVYWCFC
                     KVLFLIQARLEKRFDRYVAK"
     gene            complement(38718..39545)
                     /locus_tag="ACFOAE_000180"
     CDS             complement(38718..39545)
                     /locus_tag="ACFOAE_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6883757.1"
                     /translation="MMLKKFVLGGIAALVLAACGGSEGGSGASSAPAQSAVSGSLIER
                     INNKGTVTVGTEGTYAPFTYHDKDGKLTGYDVEVTRAVAEKLGVKVEFKETQWDSMMA
                     GLKAGRFDVVANQVGLTSPERQATFDKSDPYSWSGAVLVARNDSNIKSIDDIKGVKTA
                     QSLTSNYGEKAKAAGADLVAVDGLAQSLTLIEQKRADATLNDELAVLDYLKKNPNAGV
                     KIVWSAPADEKVGSGLIVNKGNDEAVAKFSTAINELKADGTLKKLGEQFFGKDISVQ"
     gene            39830..40738
                     /locus_tag="ACFOAE_000181"
     CDS             39830..40738
                     /locus_tag="ACFOAE_000181"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
                     /protein_id="HFC6883758.1"
                     /translation="MNTPQSAIIPDHAQAGIFIEADFAANRLNDIKAACRASLDALTA
                     LKARFPDDILGLTIAFGSKAWATFGHTDEGSEIKPFSEMGNGLAPSTQHDMSIHIQSF
                     RQNAAYALAQSVLGAFGDSICVASEEHGLRLYQDRGLDGFVDGTENPQGDENVREVAI
                     IPEGKPDAGGSYVLLQKYLHDLKKWDAVPVAEQEASVGRGKETDDEFGRDVRLPDSHL
                     GRVNLKENGVGLKIVRRSLPFGKISGEHGLMFTAYCRTLHNIEAQLLSMFGDTDGKTD
                     LLLRHLSAAVSGGYYYAPSVERLQNL"
BASE COUNT         9801 a        11025 c        10006 g         9951 t
ORIGIN      
        1 gttgttgcag attgccgttt ttttcggtgg gctgaagccc accctaccga aaggcaagca
       61 gctgttcgcg gtaatattcg tattgtttgc ggcgcagggc gatttcgtgc ggcaggcctt
      121 cgctgatgga gtgggtcagg gtatcgaatt tgtcgaggat ggcgacgatt ttttcttgtt
      181 cggggagtgg agggatgggg attgggaagc gtttaaaacc attcatatcc acagaagcaa
      241 aactcgatgt tgtcgtattc tttttgcacc attcactaag attaaaacaa tagtaataaa
      301 gaaaataaat gctgagttta tcggcaaatt caggctttaa agataaactg gtaaatcttt
      361 ggttggctaa gaatggaacg gttattagtg catgctcacc tatggttgca gatgtagcca
      421 tgataataga attggctgga aatagcttac cgccctttac tgcgcttttt gatatatgct
      481 gtaatgaatt atctaaaata cgaccatttt ccctaatatc ttccattcta aaccaaggga
      541 ttgagccatt ttcccaatat tctttatttg atttggaagg ggtatagcca ttcttcaagt
      601 caaacacctc ccccaacgtc ttccaaacca catctttcag acggcattga tagccatcag
      661 ctatcccccc cgatttgatt gtcaaaatct aaaagaaagt cgcggtaata ccggtattgg
      721 cgtttgcgca gggctaattc agcttcaagc tcggtgaatt tgtcaagtat ttttacaatt
      781 ttttgttggg tttccagggg tgggataggg attaataatt ttttcaagtt actggcattt
      841 agagcaggaa tacctgtaaa tgtacataag gcatgaatct cttgttcaaa ttcaagtaat
      901 atatgataga gaaaacgaac atccaattct gttctattct taatagtaac tgcataattt
      961 aagttgccac gaaaatatct tccttcttgc cacgttattg agccgactcc cgctcctctt
     1021 gttgtgatgc cgatagggtc attttcagtg ttccattcat caatatagcc aagcggctct
     1081 ttgccactgt taataactgg ataactacca atattatttg agattttctg cttacttaca
     1141 gcttgtcctg tttttatgat agctatccca ttttctccac ccaacggctt ccactccacc
     1201 ggtgccgtct gaatcatctc aatcaatttt ttcgctttgc tttgcatatc catggttgtt
     1261 ttccgtttct ttcccgctgt ggcgggatgt ggggcggttg tggggtgctt cggctcactc
     1321 tgtccgtttg ccgttatttc tgcgggctga agtccgtcct gctttcaggc tgcctgcaat
     1381 ggtgtgcagg ctgctttttc aggtagcctg aatggtagtt attttgtgcg gtcttttttc
     1441 tgtttgatct gttgcacggc tgttttttcc aacgctttaa cgctttccag ataggcttgc
     1501 tccaccggcg acaggatgcg cgcttcatag gcgcggtatt cgcgttcggc tttctgctct
     1561 gcctgtttgc ggctgatgct gcctgcaccc tgtaatgtgc cttgtccgta cagcccggaa
     1621 aatttgtcca attcggctat ccagtcgcgc atatacatgg ggctttgctc ctgcgctttg
     1681 atttccgcca ggtcgaagaa ggcggaaacc agacggttca ggcggaacag ttcgtcttcg
     1741 gtcagatagt ttttggcgat tttggcttca ttcagcgtgg ggattgcgcc ttgaaaggtg
     1801 gtcagcccca taaagtcttt gctgctgtcg gcacggctgt atatcagctc agctgcggtt
     1861 tgccggctgg cggcatagtg cagtttgttt tgaacggcgg caaaaaaggt ttggctttcg
     1921 ctgcttttgg ggttgtagtc ttggctggtg gcatataaat caagcacttg ccggtatagg
     1981 gctttttcgc tgctgcggat gtcgcgaatg cggttgagca gttctttcca atagttgccg
     2041 ccgcctgtgc ctttcaggcg ttcgtcgtct atggcaaagc ctttggtcag atattcgtcc
     2101 agccgttcgg ttgcccattg gcggaattgg atgccccgcg cggaacggac gcggtagccg
     2161 acggcaataa tcatgggcag ggaataatgg gcgattttgc ggtttacctt gcgcccgttt
     2221 tcattttgaa ctgtcaactg gaagttgaca gttgccttct cttccaattc ttgctctgca
     2281 agaatggttt taatgtgttt gctgatattt tgtttggtgg tttggtacag ttctgccatg
     2341 tccgcctgcg tcagccaaag ctgtccgcca aattcctgca aggcaaattg ggcagtgccg
     2401 tcgttggcgg tgtataggat gatgctcatg cttcaatctc tgcaatcact tcgtcaattt
     2461 cacgccgcag ccgttcgatt ttggcaacgg tttcgctgat ttcggcgtta agctgtttga
     2521 tgtcgataat ttcgcgggtg tcttcgggtt caacatagct gctgacggcg aggttgtagc
     2581 cgttgtcttt gacggtttgc tgggcggcgt tttgggcgat atgcggcaca tcggctttat
     2641 cggcgaagag tttgacgatt tcggcaatgt gttcttcggt taagacgttg ttgttggttt
     2701 cttttttaaa gaagccgcct gcgtcgatga attggatgtc ggtattgtct ttgtgtttgg
     2761 acaaaaccag tatattgacg gcgatgccgg tgccgtaaaa gagattgggc gcaagggcga
     2821 tgacggtttc cacgtagttg ccctccacca gatattggcg gattttctgc tctgcgccgc
     2881 cgcgatagaa aatgccgggg aatgagacga tggcggcgcg gcctctgccg gaaaggtagt
     2941 tcagtgcgtg cagaatgaag gcaaaatcgg ctttggattt cggggcgagt acgcctgcag
     3001 gggcaaagcg gtcgtcgttg attaaggtgg ggtcgccgct gcctatccag ttgatggaat
     3061 agggcggatt ggaaacgacg gcatcaaagg gtttgctgtc tttgagtttg ggattggtca
     3121 gtgtgtcgcc caattcgatg tggaatttgt tgtaattgac gttgtgcaga aacatattca
     3181 tgcgggcgag gttgtaggtg gtgtggttga tttcctgccc gaagaagcct tcttcgatga
     3241 tgtgctcgtc aaactgtttt ttcgcctgca agagcaggct gcccgagccg caagctgggt
     3301 cgtagatttt gtttactttc tcctgcccgt gcaccgccag ccgcgcaatc agcttggata
     3361 cgctttgcgg ggtgaaaaat tcgccgccgg atttgcctgc gttggcagcg tagttggaaa
     3421 tcaggtattc gtaggcatcg ccgaaaaggt cgatgtggta gtcttcaaaa ctgccgaaat
     3481 cgagttccgc cacgcctttt aggacggcgg caaggcgttt gttcttgtcg gcaacggtgc
     3541 tgccgagccg gctgctggtg gtgtcgaagt cgtcaaacag gcctttaatg tcttgttcgg
     3601 acggatagcc ggaggcggag ctttcaatcg cggtaaaaat ttctttcagc ttggtgttga
     3661 gctcttcgtt ttgatgggct tcggcggcaa tattgcaaaa aagctggccg gggtagatga
     3721 aatagccttt gactttgacg gcatcgtctt tgatttcggg cgtgatgatg ctgtccggca
     3781 tagcggcgta atcaatactg ctgtcgcctg cctgcatata gtcggtaaag ttttcgctga
     3841 taaagcggta gaaaagtgtg ccgagaacgt attgtttaaa gtcccagccg tccaccgcgc
     3901 cgcgtacttc gtcggcaatt ttccaaattt ggcggtgcag ttgggcgcgt tgttgcattt
     3961 cggtcatcat cgaaatccat ataaaagtta aacaaatcga aatcgcctga tattttcaga
     4021 cgatttttta cgggcattca aattaagcca aattttccag catccatttg acgtagcgct
     4081 cgacgcctgc tttgacatcg aaaaattctt ccgtataacc tgcctcgcgc aatttggtga
     4141 tgtcggcttg ggtgaagctt tggtatttgc ctttgagcgc gtcgggaaat gggatgtagc
     4201 ggataaattc ttcttctacc aactctttta aactcatttc aggtttgcct tcggcggcgc
     4261 ggcaggcgtt gacggtggca gcggcgagtt cgttaaactg ttggctgcga cctgttccta
     4321 ggttgtagat gccggaaagt tcgggatggt cgaagaagta gaggttgact ttggcgacgt
     4381 cttcgacgct gacgaagtcg cgggtttgtt cgccgttgcc gtagccatcg ttgctgccga
     4441 acaggttgac gtaaccgtgt tcgcggtatt ggtggaaatg gtggaaggcg acggatgcca
     4501 tgcgaccttt gtgttgttcg tgttgtccgt aaacattgaa gtagcggaag ccgacgactt
     4561 gggcggtcag cctttctttc atgcggcggc gcaatacttg gtcaaacagg aatttggaat
     4621 agccgtacac attaagcggt ttttccagtt cgcgctcttc gcggaagatt tcgcctttgc
     4681 cgtaaaccgc cgcactggag gcataaagga agggaatgcg ttcgtcctga caccagtcca
     4741 acaaatccag cgtgtactgg tagttgtttt ccatcatata caaaccgtcg tgattcatgg
     4801 tgtcggaaca cgcgccttga tggaaaacgg cttcgatgtt ttgataaggt aaaatgtgtt
     4861 ccctcacttg gcggatgaat tcatgtttgt cgagataatg ggcgatttcg cactcggcaa
     4921 ggtttttgaa tttttcgcct ttgctcaaat tatcgacggc aacaatgtca gtaataccgc
     4981 gttgattaag tgctttgacg atgttgctgc cgataaagcc ggccgcgcct gttacgatga
     5041 tggtcatatt cggtttcctt tgttttgagt aaaattaata aacttagtta caagaaatca
     5101 tcgatattgt cctgaaacac aaatttgcga tgatattcca aatatttttc tcttccttcg
     5161 ggatatattc tcatcttatt ttttgcattt ggattgatat taagtttttc ccatgtgtaa
     5221 cggcttagtc gagtaccgca aatcaaacga ccatcatcca agaaagtaat ataaccttga
     5281 tcgaacaacc aatcataagt cggcgttaaa gctaacccat ttaaataatc taatgcctct
     5341 ttctcatttt tctcagtaat acaaaccata taaggtttaa tatgactagc ccttaacaaa
     5401 atctcatctg taattaatgt aaatggacat tgcggcatat gatttataac atccttgcga
     5461 tatttctgct gcccttttct acttttctgt ttaatgattt cttgctctac gaattgatta
     5521 aattctgaag ccggtatttc taatttttct cttgataaga gttgcgggtg cacgatagag
     5581 cgaaattgat aatccaaaaa tattcggaaa taaaataatg gttctgaatc ttctatatct
     5641 ttgacaggca atagtttaag aattgataaa taactaattt tgggcaatac aatcttacgc
     5701 caaattgacc atatatcatc ctccgaacgg atataacccc tacggtaacc tttagaattt
     5761 tccaaatggt ctgatacatc atggattgaa aagaaaatat tttctgtagg cagattatta
     5821 atacttaaaa cgtaatcatc ataaaacctt gaaatatcat gatgatattt ctgttcttgt
     5881 ttgtgatatt caacttttgc atcaaccaaa taacgctgta aatttttctt attaaaaaaa
     5941 caatttttct gaatgagagg atattctacc ctccttccat tttttgtctc agtaatcccc
     6001 caattttcat actcaaaaaa tgtacttagt tttcgaccac tatcatcaat ataactacct
     6061 acatatttgc gtgcttcccc attaccacca aaaacagata acttgttatt cctgtgaata
     6121 aaactatctt ccgcacgtaa attttgaata ctatcgacaa taaaatactc tatgttttca
     6181 atagtaattc tttgaaaatc cggcatttta ctctccataa agcgtaatat ccatttgttt
     6241 taatatagcg attaatacat caacaacaat actgtttccc gcttggcgat acatttgagt
     6301 atcactaact aaaattttaa aatcatctct aaaacccatt agccgcaaac attccctagg
     6361 tgttaattta cgaatacgtc cacgattatg agtaacataa ttatcaaccc cggcacgatg
     6421 cattttatgc atagtttgca ataatgggcg agctacaggc aaatcagttt ccgtactggt
     6481 tttaaaattt tttgttcctc ctgccaaaac ataatttttg attttttcag aaagataata
     6541 tttttcctca acgttattta catcaaaaat aaagtcatca aattcagatt cgcgggctgc
     6601 ctgaaaaata aaatcaccat gccaattaaa ttgttgattt gctttttggc ataaggcaat
     6661 ttctccatta atctgtgtat aacgtttttg tctattttta gaactggtaa caaatttcac
     6721 acccttttca cgtaaaaaat atttgctatc agtatagtcc tccaaaaaat cttgcatagt
     6781 atgttctaat tcaatctttt caggaaactg aaaaccattt ataggagggg tatgaaagcc
     6841 aacaacaaaa atacgctcac gatgttgagg aatcccataa tccttactat tcattatttg
     6901 gaaatataag tcataaccaa gtgaataaaa aacacttttt acaactttcc aagtttttcc
     6961 attatcatga ttgagcaagc cctttacatt ttcataaata aatatctttg gttggacttc
     7021 atccacaacg cgagcaaatt catagaataa tgttcctcgt gtatcttcta atcctgcacg
     7081 tttgccaacc atggaaaatg cttggcaagg actgcctcca actaaaatat caacttgatt
     7141 tctaaacttt ctcgcatcaa attgagtaat gtcgttatgc caaaaatctt catttaattt
     7201 atagtttcca agataacttt ttttaacgta tggatcaata tctcctgcaa aaacaatggt
     7261 atggtttaaa tttaatcggt ggaatgcctg ttcaaccgca ccaatcccgc tgaatacggt
     7321 tgctaatcta atatgtgaat caggtttaag aaaagtttta gatttccaac cttgttgact
     7381 gggaaagagc aaagtttttt gtaatcgagt atcgtgtgtc tgtgccattg tcgaaatagt
     7441 catacttata tcgttctgtt tatcttatca atatgaaaac tacattgttg attgccctga
     7501 caatgccttg atcaattcgg caaacgagca aaccgccgta ccgagtttcg ccacgacaac
     7561 cccggccgca gtattggcaa ggtacatggc ttcgggcatg gtgcagcctg ccgccaaacc
     7621 caagcccatt ccggcaatga cggtgtcgcc cgcaccggat acgtcgtaaa cttcttgggc
     7681 gcgggtgggc tggtaaatcg gttcgccttc gctgaacaag gtcatgcctt cttcgcttcg
     7741 ggtcagtaaa acggcggtca ggtcgaggtg gcggcgcagg ttttgcgctt tttcggtcag
     7801 ctcgctttcg tttttccaac tgccgaccac ttctttcaat tcggcgcggt taggcgtaat
     7861 cagagttgca ccgacatatt tttcgtaatc gtcgcctttg gggtcgatta agacggtttt
     7921 gccggcgtgt ttcgcccaat cgatcatatc ggagatatgc gacaggccgc ctttgccgta
     7981 gtctgaaaaa atgattgcgt cgtattcggg caagatttcg cggtatttct gcttgatttg
     8041 ttccaacact tcgcagttgg gatgttcttc aaaatcaaga cggataagct gctggttgcg
     8101 ggcgacgacg cgcagtttga cggtggtggc gatttgtttg tcgcgcatca gataggaggc
     8161 gacgccgtcc tgcaccatca gcgcatcgag cgcgtcggcg gcttcgtcgt tgccggttac
     8221 ggacaacagc cctgccctgc cgcccaacga agcgatgttg cgcgcgacat ttgccgctcc
     8281 gcccgcgcgt tggtcgattc gtccgatttt cgccaccggc acgggggctt cgggcgaaat
     8341 acgggacaca tcgccgaacc aatagcggtc gagcatcacg tcgccgacaa ccaggacttt
     8401 ggcttgcgcg aaacgggatt tgagggtttc ttgttggaac ttggcggaca tattgcctcc
     8461 gttgtatttt ttcagacggc ctcagcctgt aaggccgtct gaaaatcagt ttgcttcaag
     8521 gtttgccacg cggttcactt cgcgcaatac ggctaccgga tcggcagctt gggttacagg
     8581 acgacccatt accaaataag tcgaagcggc agccaaggct tcggccggtg tcatgatgcg
     8641 gcgctggtca tcattattgc cggcaacgtc caagcggatg ccgggcgtga ccaagacaaa
     8701 atcttgtccc aactcgcggc gcagcggtgc ggcttcttgg gcggaacaga ccacgccgtc
     8761 caagcccgaa ctttgcgcca gtttcgccaa gcggatgact tgttcttcag gggcggtgtt
     8821 caaaccgatt tccgccaaat cgctttgttc catgctggtc aacacggtta cgccgattaa
     8881 gagcggcttc gtgccgtatc cggcaacggc ttctgctgcg gcttccatca tacggcggcc
     8941 gcccgatgcg tgcatatcga ccatccaaac gcccatatcg gcagcgactt tgcaggcttg
     9001 cgcgacggtg tggggaatat cgtggtattt caaatcgagg aaaagtttga aaccttgatt
     9061 gattaagctt tctgccaaat tgcgtcccgt cgcggtaaac agctctttgc cgattttgat
     9121 ttgacacaat gtcgggtcaa ggttgcggac gaatccgagc gtgtcttttt cgttggaaaa
     9181 atcaagggcg acgataacgg gggtgcgttg ttgcggagtt tggaagtcgg agattaaagg
     9241 attcatggtg ttttcgtttc gggttttcag acgaccttta tcgtcttttt cgcagtatag
     9301 tggattaact ttaaaccggt acggcgttgt ctcgccttag ttcaaagaga acgcttctct
     9361 aaggtgctga agcacaaagt gaatcggttc cgtactgttt gtactgcctg cggcttcgtc
     9421 gccttgtcct gatttttgtt aatccactat aagaacgtaa attcaaaccg taggtcgggc
     9481 attgatgtcc gacctacgcg gactcaagcc tccgacaaac tgtttcggat aaatttgaac
     9541 cggtacatca gccgtcattc ccgcgtaggc gggaatccat tgataaaact cagttcatca
     9601 gatttaaaca gcgattgccc aaattcagaa atggattccc gcctgcgcgg gaatgacgcc
     9661 aaatgattat ttttcggttg caacacgctg tttatcaaaa acaggtcgtc tgaaaacctg
     9721 attttctgtt ttcagagtgc gaagcctgcc cgtgggtacg accttttcga tttatttgcc
     9781 caatgcgccc aatacttcgg ctttcacggc ttctaccggc tgagtgccgt caactttgat
     9841 gtatttaggc gcgtgttcgc cttccagttt gctgtaaaaa tcgaccaaaa cttcggtttg
     9901 ctcgtggtaa acggcaaggc gttttttcac ggtttcttct ttgtcgtcgt cgcgctgaat
     9961 caaatcttcg ccggttacgt cgtctttgcc ttcaactttg ggcgggttgt aggtaacgtg
    10021 gtaagtacgg ccggaagcca aatgcacgcg gcggccgctc atgcggtcga caatcacgct
    10081 gtcaggcaca tcgatttcaa cgactgcatc caaatccacg cctgcttcaa ccatcgcttc
    10141 ggcttgtgcc aatgtgcgcg ggaaaccgtc aaacaggaaa ccgtttttgc agtcgtcttg
    10201 cgcgatgcgt tctttgacca tgccgataat gatgtcgtcg cgcaccaagc cgccttcatc
    10261 aatgattttt ttcgcttcca aacccaaggg cgtgcctgcc ttaatcgcgg cgcggagcat
    10321 gtcgccggta gagatttgcg gaatgccgaa cgcggcggtg atgaattgcg cctgagtgcc
    10381 tttgcccgcg cccggcgcgc ctaaaaataa tgctttcatg aagtgatcct ttgaaatgtg
    10441 tttattggaa tcaaacagat ggtttacgat tctacacggc ttggcacaat agttcaaaaa
    10501 ccaactgcac aaactgccat ttgcaagcaa atgttttgca tacctttgcc gagtctgata
    10561 ttcacaagcc ggcaactttt tgggacaatc cccaaaattt caaaacatca caccctacca
    10621 aaaaggaaca tccgtgaaac gaatttttct gtttttggct accaatatcg ctgttttggt
    10681 cgtaatcaac attgttttgg cggttttggg catcaacagc cggggcggca cgggcagcct
    10741 gttggcgtat tccgccgtcg tcggcttcac tggttcgatt atttcgctgc tgatgtccaa
    10801 attcatcgcc aaacaatcgg tcggcgcgga agttatcgac acgccgcgca ccgaagaaga
    10861 agcctggctt ttgaacactg tcgaagccca agcgcggcaa tggaacctga aaacgcccga
    10921 agtcgccatc taccactccc ccgaacccaa tgcctttgcc acgggcgcat cgagaaacag
    10981 ctccctgatc gccgtcagca ccggtttgct cgaccatatg acgcgcgacg aagtggaagc
    11041 cgtattggcg cacgaaatgg cacacgtcgg caacggcgat atggttacgc tgacgctgat
    11101 tcaaggcgtg gtcaatacct tcgtcgtgtt cctgtcgcgc attattgcca acctgattgc
    11161 ccgaaacaac gacggcagcc agtcgcaggg aacttatttc ctagtcagca tggtattcca
    11221 aatcctgttc ggcttccttg ccagcttaat tgtcatgtgg ttcagccgac aacgcgaata
    11281 ccgcgccgac gcgggcgcgg caaaactggt cggcgcgccg aaaatgattt ccgccctgca
    11341 aaggcttaaa ggcaacccgg tcgatttgcc cgaagaaatg aacgcaatgg gcatcgccgg
    11401 agatacgcgc gactccctgc tcagcaccca cccttcgctg gacaaccgaa tcgcccgcct
    11461 caaatcgctt taaaccgatt tgaaacggca aaaaccgtac gcgcaagcag tacggttttt
    11521 tgtatatgct gtctgaaaac atcaggtttc cataccgaca ccaaccgtat ccatttccgc
    11581 accggatacg ccgcattgat ataccctgat aaaccgtatc cggacagaaa atatagtgga
    11641 ttaacaaaaa ccagtacggc gttgcctcgc cttagctcaa agaaaacgat tctctaaggt
    11701 gctgaagcac caagtgaatc ggttccgtac tatttatact gtctgcggct tcgtcgcctt
    11761 gtcctgattt ttgttaatcc cctatatcag ataaaacagc ggtaaaattg ccgtctgaaa
    11821 ccaactctgc gccatacggg acacgctctg cacgtctatt tgcctccgat atatcctccc
    11881 tactgtagga acgtctgccg atttgcacga aatcggcacc tctagcaccc ttcaggatgg
    11941 cggacgttat ccgttcttgg gattctgcaa gacggtcgac ggcattatac agacgctcgg
    12001 tctgataccc ttccgaagca acctgcttca ggtattccaa ataaccgtaa cccaacgccc
    12061 ctccgacaag cagggtcgtc aacgctacca gcgttgccga acggatttta gggggcatat
    12121 cttgaagcat atctctaccg aaccgaacca aagtctcttt aaagtcggac tctacacgcg
    12181 tagaaccctc ggaaatcttg aagttcaact catactgctt ccgtttgtcc gctgtcaacc
    12241 gcttgaggtt gtcatccccg tattggacgg ttgacacaac cctgtacaga ctgtcctgta
    12301 tttcgaccag cgtctgtgca aagttggcgg tcatactgga ttcccaaccc ttgccgccga
    12361 ttctgatact caaaacggta tccaggcgtt ccagcagggc ttcgggagac agcagtgcgt
    12421 attcttcaat attttccata ggttgattat agcagaacct tatacctgtt acagacaagg
    12481 ttgtcgggat ttgaacgtcc gtcgagcttg gttcgtatag agccgtaggg gatgtttagg
    12541 gctttggcgg cagcttgtac gctggggaac gtgagtgttt cgcctgtggc ggtgtcgagg
    12601 atggagacag gtttttggtt ttggggaggc gtattttcct tcattttaag tttcccgcac
    12661 tccggacacc catactttga ctttatagct gtgtcgtaat acaaaagttg gacaaccccg
    12721 tgcgtaggac atctaacact ggaaggttta taaatgccac tgaactccaa caattctaaa
    12781 tgtggaaatt tctcttgaaa gcgtgatttg gcggtatcga aagtcattcg cttacccata
    12841 atttgtctcc ataggttatg tgcaaatgga ttacacaacc aaaatataga aattttcaaa
    12901 ttttttgaga cctacctgga atcctgcgca agcacaatgt aaagaaaaat ggtatacgtc
    12961 tttactaaat ctttacataa attaactcta atcgggattt gaacgtccgt cgagcttggt
    13021 tcgtaggatt tagggtgttg tgaaccttac ctatcgtacc caagcacttt gtacctgttt
    13081 gaaataaggt tgtcgggcga cgttcgaccc ttgagcctgt gattgatttg ttggaaatgt
    13141 acacctaaag cagcacctgc ggcagtaacg cttgggaacg tgagtgtttc gttggtcgtt
    13201 gtgtcgagga tgaggagggg cttccctaca tttggaggtg tttgggtttt tgacatctta
    13261 gcacactcag gacacccgta ctttgacttt ataagggcat taaatgtcga ataacgaacg
    13321 ttcccgtgca taggacaatt aacggttact gggtaattca caccgtcaaa gccggttaga
    13381 gagatattag ggaatatatc agtaagttca gaagctgctt ggttgaaaga tttggccatt
    13441 tgagactcca aaattgattg tcaaatggat ttaatagcaa atttataaaa atgtcaaatt
    13501 tttcgagaag cacctgatag tggcgagggg tatacactgt taaaaagtgt atacgtcatt
    13561 tagtgcagat gtgaacctta tacctccctg caagtaaagt ctctgtgtga acccgacctt
    13621 ttatacggtc agtgatagct gctgggttta tacccaatga ccttgcagca gatgctcttg
    13681 aggggaatgt aagtgtttcg ccagttacag tatcctccaa tactgtattt ttagataatt
    13741 tatctattgt atcttctgga attttgtggg aattgacacc ataagatgca cattttggac
    13801 acccactttt agagtccaac atacttttga atgtagagca agtaaccctc ccgtgtatag
    13861 gacagacgat taccgtcggg taacgaacgc cattgaactc cacaagattc aaatgtggaa
    13921 atttagaggt tagcttagaa actgcttgag taaatgtaag tgccatagtg gttgtgaact
    13981 tactttacca acctataacg atacctaatc aatcggtcaa acggagtgcg tccgcttaaa
    14041 cgtacagcta aagtgctgtt ggagcaaccg ataaatttac tggcagccag tgtacttgca
    14101 aactcgtaga tttcccctgt ctctgtgtcc tccaacctaa tggcaacggc gtttggagag
    14161 ggcttttcgg gatttcgagt acattcagga catcctgttg aggatttcat ggcagcttgt
    14221 agattcccgt aaacaaccga cccatgcaaa gggcattgga ttgttaccgg ttcgtagttt
    14281 ttagtgaact tcaaaaccgt cttatcagga aatttactgg aaaaccttaa ctgaacatct
    14341 tgtagcgaga gtgattttgg cattatagac ctttctaaaa tgaaagcatt atacaaccaa
    14401 aatatagaaa ttttcaaatt ttctctgaac gcactggtat ccgatggagc taaatgtaaa
    14461 gaaaagggta tatgtcctta ctaaatcttt acacatttta actgtatagt gtttgacaag
    14521 caacaggcat aggcgcataa tgcacccgta gttagataga tagtaaggag ataaccaatg
    14581 acttagcacc tgcccccctc tctctcgcgc accccgcccc tcgcttgcgg ctaatgggct
    14641 ttgcgcgaaa tatacacttt catctcctgc atggcttaac cgcctatgca atagtacaca
    14701 catcaacaaa tcaggctggc acgtcttggc attggctgac gtaccattgt agcccgaaat
    14761 gttgataccc tactatttat gaccaacggc ggattagggc ttcagacggc aattttactg
    14821 caaaacctta tgcgaacgga tgatgcagca caatcgtttc ttctcggtcg gggccggtgg
    14881 agacgatggc gaccggcgcg ccgcagactt cttcaatccg tttcaaatat gctttggcat
    14941 tatcgggcag ttcctcataa tttttgatgc cgaaagtcga ttctttccaa ccctccattg
    15001 tttcgtaaat cggtttgcag gtttccaccg catccgaacc gcaaggcagg atatcggttt
    15061 tgccgccgtc gggcaattcg tagccgacgc agatattgat ggtttcaacg ccgtccatta
    15121 catcgagttt ggtaatgcac ataccggaaa tgccgttgat ttggatggag cgtttcaggg
    15181 cggcggcatc aaaccagccg cagcggcgtg cgcggccggt taccgagccg aattcgtgtc
    15241 cgcgttccgc caaacctgcg cctacttcgt cgaacaattc ggtcgggaac gggcctgaac
    15301 cgacgcgcgt ggtataggct ttgacgatgc ccaaaacata atccagcatt tgagggccta
    15361 cgcccgcgcc tgcggaagcg gctcccgcca gacagttgga cgaggtaacg aagggataag
    15421 tgccgtagtc gatgtccaac aacgcacctt gcgcgccttc aaacagcagt ttttcgccgt
    15481 ttttgttttt ctcgttcaac acgcgggaca cgtcggtaat catcggcgca atgcgcagcg
    15541 cgactttttc gataaccgcc atcacgtctt ccgctttaac cggctcggca ttgtgcagat
    15601 gttgcagttg gacattgtaa taggcaagga tggcatccag tttttcacgc agtttttcag
    15661 gatgcagcaa atcggcggcg cgaatggcgc ggcgtgccac tttgtcttcg taggcagggc
    15721 cgatgccgcg gccggtcgtg ccgattttgc ctttgccgcg cgatgcttcg cgggcttggt
    15781 cgagcgcgat gtggtaaggc aggatcagcg ggcaggtcgg cgcgattttc agacggcctt
    15841 cgacgttttt cacgcctgca gcgtttaact cgtcgatttc gcccaacagg gcttcggggg
    15901 agacgacaac gcccgaaccg atgaagcagt ccagactttc atgcaggatg ccgctcggaa
    15961 tcaggcgcaa aatggttttt ttgccgccga cgaccaaagt atgacccgca ttgtggccgc
    16021 cttggaagcg caccacgccg ccggcttctt ccgccagcca gtcaacgatt ttacctttac
    16081 cctcgtcgcc ccactgtgcg ccgattacta caacattttt agccatagcc atataaccta
    16141 tcgatattaa aaattattgc ggaaatcccc aaaccggtgc ggctttgcgc cccaccacga
    16201 tttgcctttc atccgccatg aacgggtatt tagcgtttca cgacctgcca aacgccgtcc
    16261 gtctttttca gacggcctgc aagctcttcc gaaacattgt gtccgatacc gtagtcaacc
    16321 acgacacact gcccttgttc acgcaaggct tcgaccgctt cgcgcgccgc ttcggcatct
    16381 tccgcatcga ccaacacggc gggctgccgt tcgatggcgg gcaaacgccc gataaagctg
    16441 cgcaagtcga aactgaatcc cgttgccggg cgcgccctgc cgaaatatcc gcccaatccg
    16501 tcataacgcc cgccgcgcgc gaccgcgtcg tggaaatcgg cggcataggc ggcatacagc
    16561 aagcccgtgt ggtaattgtc gacacgcagc tcggacaagt cgatatggat ttcacaatcg
    16621 gggaatgcgt cgcacaccgc ctgcaattcg tctaacgcgc cgccgaccgc cgacaaatcc
    16681 ggcaaccgtc cgcgcgcgtc ggacaacact tcacgcccgc cgtacaggcg cggcagcagc
    16741 gagaatgctt ttgcccacat gccgtccagc ttccaagcct tgacctgcgc ttcgaccgcc
    16801 ccggtatctt tatcctgcat caaggcaagc agcgttgcgg actgccccgc atccaaatgc
    16861 gccgcatcgg acaaggcgcg aaatatgccg atatgcccca gcgaaagcag cactttgccc
    16921 atatcggcaa ttttcatgct tttcagcatc aggtctatca gctcgatgtc gccacggatg
    16981 tcggcaaaac cgtacatttc cgcccctgcc tgcaagggtt cgcgcatatt cagcagaccg
    17041 tcgggctgcg cgtgcaacac cggaccggca taacacaacc ggttaatccc ttggttggcg
    17101 gataaaagat gggcatcgat acgcgccacc tgcggcgtga tgtcggcgcg tatgcccaac
    17161 tgcctgccgc tgagcctgtc cgttaccaaa atggttttca gggaaagccc cgcatcgata
    17221 tgcgtcagca gggaatgtgc gtactccatc agcggaggct gtaccagttc ataaccgtgt
    17281 acgcggaaca gtgccaacaa ctgctccctc gcgctttcaa gctgccgcgc gttcgtgggc
    17341 agtacgtcgg cgatatgttc cggaagctgc catgtctgca tgagaatctg ccttctattt
    17401 tatcctgtaa acacaaaaga ctgcccgatc cgcaatcaga cggcatcttt gccgcaacgc
    17461 atcacgccgc tgtcaaaacg gcggtgcttc cttccgattc agaatccgaa cagcccctgt
    17521 ccgacggctc aatgccgtca agtcgttaaa accaaacttt accataaaat acacacaatc
    17581 tgaatatact tttataccct gtatccgccg tctgacggca cggcattttt ttactatata
    17641 atgtgcacca ttatttctca tcacttcctg ctgccgtttt ctgcttcaga cggcattttt
    17701 gttgattgaa cacttatgct gctcgacctc aaccgctttt ccttttccgt cttcctgaaa
    17761 gaagtccgcc tgctgaccgc tcttgccctg cccatgctgt tggcgcaggt cgcgcaggtg
    17821 ggcatcggtt ttgtcgatac cgtgatggcg ggtggtgcgg gcaaggaaga cttggcggcg
    17881 gtggctttgg gcagcagcgc gtttgccacg gtttatatta cctttatggg cattatggcg
    17941 gcgctgaacc cgatgattgc ccagctttac ggcgcgggta aaaccgacga agtgggcgaa
    18001 acgggacggc aggggatttg gttcgggctg tttttgggcg tgttcggcat ggtcttgatg
    18061 tgggcggcga ttacgccgtt ccgcaactgg ctgaccttga gcgattatgt ggaaggcaca
    18121 atggcgcagt atatgctgtt caccagcttg gcgatgccgg cggcaatggt acaccgcgcg
    18181 ctgcacgcct acgcttccag cctgaaccgc ccgcgcctga ttatgttggt cagcttcgcg
    18241 gcgtttgtgt tgaacgtgcc gctgaactat attttcgttt acggcaaatt cggtatgccc
    18301 gctttgggcg gcgcgggctg cgggttggcg acgatggcgg tgttttggtt cagctcgctg
    18361 gcattgtgga tttatatcgc taaggaaaaa ttcttccgcc cgttcggact gacggcaaaa
    18421 ttcggcaaac cggattgggc ggtgttcaaa cagatttgga aaatcggtgc acccatcggg
    18481 ctgtcttatt ttttggaagc cagcgcgttt tcgtttatcg tgtttttgat tgcgcccttc
    18541 ggcgaggatt atgtggcggc gcagcaggtc ggcatcagtt tgtcggggat tctctatatg
    18601 attccgcaaa gcgtcggctc ggcggggacg gtgcgcatcg gcttttcgct tgggcggcgc
    18661 gaattttcgc gggcgcgtta tatttcgggc gtgtcactgg tgttaggatg gatgctcgcc
    18721 gtgattaccg tgctttcctt ggtattattc cgttcgccgc tggtaagtat gtacaacaat
    18781 gatccggcgg ttttaagcat cgccgccacc gtcttactgt tcgccggctt gttccaaccg
    18841 gcagacttca cccaatgtat cgcctcctac gccttgcgcg gctacaaagt tacaaaggtg
    18901 ccgatgttca tccacgccgc cgccttttgg ggctgcggcc tgctgccggg ctacctgctc
    18961 gcctaccgtt tcgatatggg catttacggc ttctggacgg cattgattgc ctcgctcacc
    19021 atcgccgccg tcgccttggt gtggtgcttg gaattgtgca gtagggagat ggtcagatcg
    19081 cataaggtcg tctgaaaacg cagtacactt caattcaaat acagttaaag ttcaaaccat
    19141 gcaacccatc cgataccgaa ccgacctcac cccctacaac actttcggcc tgcgcgccca
    19201 agcccgagcc tttatcgcgc tcgaacatgc cgacgagttg tgcgacatcg tccgactgcc
    19261 cgagttcgac cgcgatactg ttttatggct gggcggcggc agcaacatcc ttttgatgca
    19321 ggattacgcc ggactggtcg tacacatgga aaacaaaggc atacgcgaga ttgcgcgttc
    19381 agacggcatt gttcgcatcg aagcgcaggc gggcgaaatc tggcacgatt ttgtcctgca
    19441 cgccgtcgcg ctgggtttga acggtttgga aaacctgagc ctgattccgg gtacggtcgg
    19501 cgcgtcgccc gtgcagaaca tcggcgcata cggcgtagag gcgaaagatg tgattcacag
    19561 cgtgcgctgc tttgatttgg atacggagac ctttgtcgag cttgccaatg ccgactgccg
    19621 cttcgcctac cgcgaaagcc tgttcaagca ggaaggtaaa gggcgttatg tgattgtttc
    19681 ggtcgtattt gcattaaaaa cgcattttgt gccgaacttg ggttacggcg atttggcggc
    19741 cgccgttgcc gaactgagcg cgggcagggt gccgacggcg aaagatgttt ccgatgcagt
    19801 gtgtgcaatc cgcaacagta aacttcctaa tcctaacgtg cttggcaatg tcggcagttt
    19861 ctttaaaaac cccgtcgtca gcgcagaaaa agccgccacc ttgttgcagc ggcatcctga
    19921 tatgccgcgc tatccgcagc ccgacggttc ggtcaaactc gccgccggct ggctgatcga
    19981 ccaatgtcgt ctgaaaggct ttcaaatcgg cggcgcggcg gtacatgaca ggcaggcttt
    20041 ggtcttagtg aacaaaaaca atgcctcggc aaacgatgtc cggcagttgg cgcaacacat
    20101 caaatttaca gtatttgctc ggtttcaggt agaattgcac gccgaaccca attggctgcc
    20161 tgcttcgttc agcctgtaaa tccaaggagt atgcccgtga cccgccccgc caaaatcaat
    20221 acttacacac gcatcatcga cgccagcctt gcgcttttca acgaggaagg cgagcgcaac
    20281 atcagcacca accatattgc cgcccacttg ggcatcagtc cgggcaacct ctattaccac
    20341 ttccgcaaca aagacgaaat catcgtccaa ctgttcaaac gttacagcga agccctgctg
    20401 gaatacctca acgaagccgt gttgccgtct gatgtggaag actccatcaa ttatatggcg
    20461 ggcatttacg acgtgatgtg ggaataccgc ttcctattca gcgacgtgaa caccctgctt
    20521 gcacgcagtg ccgaactatt gggcgaacac aataccttca cccaagccaa agtctccccg
    20581 ctcttggtca acctgctgac ccagctcaac ggtctgaaca tcatccaagc cgaccaaacc
    20641 gccatgaacg acctcgccgt caatatgtgg atgatcacga aatactggtt cgacttcgac
    20701 agctccctgc gcggccgcac caagctgacc gaagactcca aagcacgcgg catccgccgc
    20761 accttaagcc tccttcgtcc ttatcttttg cccgaacacc gcgagaaata cgaccggaaa
    20821 atcggcaacg gcaacccgta aacccacagc gtccgaatca gccttcagac ggcacttacc
    20881 cgacggtatc agcgaatgcg cgcagtcccc ccgccccata tctccatcac aggcctaggt
    20941 tacctcggcc tgccgctggc acaaaagttt taccaacacg gcagccgcgt cgccgccata
    21001 aaacgcagcc tgacttcgga cgacatcaac ctgcccatac atctcgacac cttcgacctc
    21061 ggcagcaccg atgcctttca gacggcattg tggcggcacc acgccgacaa acccgtctgg
    21121 ttcttcctgc taccgccctc ctcgctgacg cattacgccg acaccgtcaa acaatgggca
    21181 gaacttgccc gggcgtgcaa cgtgcaacac ctgattttca caagcagtac cagcgtttac
    21241 ggcgatacag cgcgcgaatg cgacgaaatc gccctacccg atccgcaaac cgagtccgcc
    21301 cgccaaatcc tcgccgccga acaacacctg ctcgacagcg gcatctccaa catcgacatc
    21361 ctgcggctgg gcgggcttta ttgcgccgaa cgccatcccg tcagccgcct tgttcaaaag
    21421 caaaacatcc cgggcggcaa ccgccccatc aacatcgtcc accgtaatat cgccgtcgaa
    21481 agcctgtttc agacggcatt taaccccggc ggcaggcggc tgaaaaacat tatcgaaccg
    21541 cgccacccga cacgacgcga attctatacg gaagaagccg ccaaactcgg cctgcccgcg
    21601 ccggatttcg cacccgacga cagcgtgggc aaaatcatcc gtaccgtttg cgataacggc
    21661 ttaagcctgt aaaataagcg tcaacagcaa caaacaggca ttctccgccc cgatcagaaa
    21721 atatgtccgc cctcctcccc atcatcaacc gcctgattct gcaaagcccg gacagccgct
    21781 cggaacttgc cgcctttgca ggcaaaacac tgaccctgaa cattgccggg ctgaaactgg
    21841 cgggacgcat cacggaagac ggtttgctct cggcgggaaa cggctttgca gacaccgaaa
    21901 ttaccttccg caacagcgcg gtacagaaaa tcctccaagg cggcgaaccc ggggcgggcg
    21961 acatcgggct cgaaggcgac ctcatcctcg gcatcgcggt actgtccctg ctcggcagcc
    22021 tgcgttcccg cgcatcggac gaattggcac ggattttcgg cacgcaggca gacatcggca
    22081 gccgtgccgc cgacatcgga cacggcatca aacaaatcgg caggaacatc gccgaacaaa
    22141 tcggcagatt ttcccgcgaa cccgagtccg caaacatcgg caacgaagcc cttgccgact
    22201 gcctcgacga aataagcaga ctgcgcgacg gcgtggaacg cctcaacgaa cgcctcgacc
    22261 ggctcgaacg cgacatttgg atagactaac cttcagacgg catccgacat gaacagccct
    22321 tttcacaaca tcggcatcgt aacccgcccc aacacgcccg acatccaaga caccgcacac
    22381 acgctgatta cctttttgaa gcagcacggc tttaccgtct atctcgacga agtcggcata
    22441 aaggaaggct gcatctatac ccaagacacc gtcggctgcc atatcgtcaa caagaccgaa
    22501 ctggggcaat actgcgacct ggtcgccgtt ttaggcggag acggcacctt tctctccgtc
    22561 gcccgcgaaa tcgccctgcg cgccgttccg attatcggca tcaaccaagg gcatttgggc
    22621 ttcctgaccc aaattccccg cgaatatatg acggacaagc tattgcccgt tttagaaggg
    22681 aaataccttg ccgaagagcg catcctgatt gaggccgcac tcatccgcga aggcaaaacc
    22741 gccgaacgcg ccatcgccct caacgatgcc gtcctctccc gtggcggcgc cggacagatg
    22801 attgagtttg aagtcttcgt caatcgggaa ttcgtctata cccagcgttc ggacgggctg
    22861 attgtctcca cccccaccgg atcgaccgcc tattcgcttg ccgccggcgg ccccatcatg
    22921 caggcaggat tgcacgcctt cacgctcgtc cccatctgcc cgcaatccat gaccaaccgc
    22981 cccatcgcca ttccagacac gtccgaaatc gaaatcctcg ttacccaagg cggcgacgcg
    23041 cgcgtccatt tcgacggtca aacccatatc gacgtgcaaa acctcgaccg catcaccatc
    23101 cgccgctacc gaaacccctt acgcatccta catccgaccg actaccaata tttcaaaacc
    23161 ctgcgccaaa aactgcactg gggcgaacaa ttggtctgaa ccgaccctta ccggaaaaca
    23221 cctatgaatc caaaaactcc ccccgaccat acagaagatg ccgtgcgcct gtccaaacgc
    23281 atggcgcaac tggggctttg ttcgcgccgc gaagccgacg gctatatcga acagggttgg
    23341 gtaacggtca acggcaaaac cgccgtactc ggtcagaaag tttcgccggc agaccgtatc
    23401 gaactaaaca agaaagccca cgaacagcag gcggcacgca ttaccatcct gctgaacaaa
    23461 cccgtcggct atgtcagcgc acaagcggaa aaaggctata aatccgccgc cgaactgatt
    23521 acccctgaaa atcactggga aggcgatacc ggccgcatcc gtttcgatcc gaaacacaaa
    23581 atcggcctcg cccccgccgg caggctggac atcgactcgg tcggattgct ggtattgact
    23641 caggacggcc gtatcgccaa gcagcttatc ggcgaaaaca gcggcagtga aaaagaatat
    23701 ttggtgcgcg tgcgcggaaa attggacgaa aaaggacttg ccttactgaa tcacggattg
    23761 agtttggacg gtgagaaact gcgtcccgcc caagtagaat ggcaaaacga agaccaactg
    23821 cgcttcgtgt tgaaacaggg caaaaagcgg caaatccgcc gtatgtgcga actggtcgga
    23881 ctgcgcgtcg tcgggctgaa acgcatccgc atgggcaagg tcaaactcgg caggctgccg
    23941 cccggcaaat ggcgttatct tgctcccggc gaatcgtttt aaataagcat taaaaaatgc
    24001 cgtctgaacg tccttacgtt ttcagacggc attgccttat gcccaaataa cggtttcttc
    24061 caagggcctg cgcgccttcg tggcgatttc ctgaacgcgg taaccgaatg tcgcggcgac
    24121 ggacacgccc cattctgccg catcgaacaa accgaactgc ccggacaata cgcgttccat
    24181 atcggcatag ttgaaacctt ccaccgggca ggaatcgata cctgccatcg ccgcacccgt
    24241 catcatgttg cccaacgcga tataggtctg gcggcaacac cagtcaaaca aggcgcgcga
    24301 atcgtccaaa atcttgatgt cgtcggcttg aaacgcctga tacctcgcca aagattttgc
    24361 catggcatcc ggttcggtaa cgccgcgccg tttgaggctt tccaacataa acgggctgtc
    24421 gaagcgggca tttttctttg ccaaaaacac caccaaatga ctggcggtat ccaaagcatc
    24481 cgccataccc caagaaaacg gcttgattgc ctgtcggatt tcggggtttt gaaccacaac
    24541 aaactgccaa ggctccgaac cgaccgaact gggcgacaaa cgcccgagtt ctaaaataaa
    24601 ctgaaaatcc tcggcactga ttttacgtgc cgcatcgtaa tgccggcatg atttgcggtt
    24661 tttaaatgcg gatagaacct gctctctgtc taataccgtc atagtgcatc ctttcattac
    24721 ttgtattgca aattgatttc aaaccgatac ggcggcagat tcgccaataa cgcccaaacg
    24781 cctttcagac ggcatttggt tcatcgcaaa cacgcctacg ggtaggcgat ataggcataa
    24841 gccgaatggt tgtggataga ctcgaaattc tcgctctcga cgacgaaact cttgatgcgt
    24901 ttgtcggcga tcagcgaagt agcgacatcg cgcaccatat cttccacgaa tttcgggttt
    24961 tcgtaggctt tttcggtaac gtatttttca tcggggcgtt tgagcaggcc gtagagttgg
    25021 cagcttgcct gtgcctccac ataatcgatg acttcctcaa taccgacttc ggcatcggca
    25081 gtcaggctga cggtaacgtg cgaacgctgg ttgtgcgcgc catattggga aatttctttg
    25141 gaacacgggc aaagcgaggt tacgggaatc atgaccttca tactgtggcc gtatgccccg
    25201 tctttgattt cgcccgtgag acagacatca taatccagta aggaccgaat accggaaacc
    25261 ggcgcggttt tcttgcggaa aaacggaaaa gaaacgctga ttttgccggc gcgggaatct
    25321 aaaagcgcga ccatttcggt agtcagcttg cgcaattgtg caaaatccaa ggcttcggca
    25381 tgttgctcca tcaatgcgac aaaacgcgac atatgcgtcc ccttctgctc agcaggcagg
    25441 taaaccgtca tggtcagacg ggcaatggtg gactggatgc cttctgcagt ttgcagggta
    25501 atcggaaagc gcaggtcttt gataccgacc tgattgatcg gcagattgcg caaatctcgg
    25561 ctggattgca cgtctgcaat agtgttcatg agttgttttt ccttaatatt catgtaattg
    25621 ttgagatgtg tgcatggtat ggcgtttccg ccggggaata taccgtcaat ctgcaaatgc
    25681 gagattatat cactcgcttt tagcagctgc attgattgtt tctatttttc agatagtgat
    25741 aaaatcttcg attattcaca tctacatagg cagagaccaa atgaaattcg ccacgaaagc
    25801 cattcattcc agctacgatt gcgacgaaca caaccgcgcg ctgatgccgc cgatttatca
    25861 aaacagtatg tttgcgttgc acgagattgg cgaaaatgtg ccttaccgtt attcgcgcct
    25921 gagcaacccg acccgtcaga ttttagaaga caccgttgcc gatttggaac acggtgcggc
    25981 aggttttgcg ttttccagcg gtatggcggg aattgatgcc gtatggcgca ctttcctgcg
    26041 cccgggcgat accattgtcg ccgtcgccga tatttacggc ggcgcttatg atttattggt
    26101 cgatgtttat caaaaatggg gggtgaacgt tgtttttgcc gatttaggca atccggataa
    26161 tttggacgaa ctgcttaaag cgcacaaggt caaactggtt tggctggaaa cgccgtccaa
    26221 tccactttta cgcttggtag acatcaaagt ccttgccgca aaagccaaag cagccggtgc
    26281 gctggtcggt atcgacaaca cttttgccac gccgtatctg caacagccgt tggatatggg
    26341 ttgcgatttt gtattccatt ccgctaccaa atatttgtgc ggccattccg acgtgttgat
    26401 gggcatcgtc gttgccaaaa ccaaagaact ggcgcagcct ttgcacgata tgatggtgca
    26461 taccggcgcg gttgccggcc cgctggactg ctggctggtg ttgcgcggca tcaaaacact
    26521 ggctctgcgc atgaacgccc attgccaaaa cgcactcgaa atcgcgcgcc gtttggaagc
    26581 ccatcctgcc attgaaaaag tgttccatcc cggcctgccg tctcacgaac attacgaact
    26641 ggcgaaaaca caaatgccca aaggcatcgg cggcgtggtt acggtttatc tcaaaaacga
    26701 cacgcgtgaa gcggcaaaca gcgtgattaa aaacatgaaa ctggtcaaaa tggcttccag
    26761 cctcggcggt gtggaaagtt tggtcaacca ttgctattcc cagtcccaca gcggcgtacc
    26821 gcatgatgtg aaaatggaaa tgggcatcaa agtcggtctg ctgcgtttct ccatcggcat
    26881 cgaagacgcg gacgatattt ggaacgatat ttccgccgca ctcgatacaa ctttgtaaac
    26941 cgtaaaaatg ccgtctgaaa ccatggtttc agacggcatt tcaattaacc cagccgaaaa
    27001 tcaacgcttc agcatctttg ccgcctcaat ggcgtaatag gtcaaaatcc cgtccgcgcc
    27061 cgcacgtttg aatgccagca ggctttccaa gaccacctta tcgccgtcca gccagccgtt
    27121 ggcaaccgcc gcctgcagca tcgcatattc gcccgaaacc tgataggcat aagtcggtac
    27181 gccgaactcg tccttcacgc ggcggacaac gtccaaatac ggcaaaccgg gcttgaccat
    27241 taccatatcc gcaccttcct gaatgtccaa cgccacttcg tgcaacgcct catcggtatt
    27301 tgccggatcc atctggtagg ttttcttgtc cgccttgccc aaattgcccg aactgcccac
    27361 cgcatcgcgg aacggtccgt aaaacgccga agcatatttg gcggaatacg ccataatccg
    27421 cgtgtggata tgcccggcat cctccaaagc ctcacggatg gcaccgatac gcccgtccat
    27481 catatcggaa ggggcaacga cctgcgcgcc cgcttcagcg tggcacaaag cctgcttgac
    27541 caaaacctct acggtttcat cgttcatcac ataaccgttt tcgtccgtca gcccgtcctg
    27601 accgtgaacc gtataaggat cgagcgcgac atccgtcata atgcccagtt cgggaaacct
    27661 ctcgcgcaag gcgcggacag ttgacggcac gagtccttcg ggattgtacg cctcctgcgc
    27721 acgctcggtt ttgtttgccg taaccacggg aaagagtgcc aacatcggaa taccgagctt
    27781 caccgcctct tccgccgtaa acagcagcct gtccaaactc tgacgcttca cgcccggcat
    27841 agaaggcaca tcctcctcgc gcgccgaccc ctccaatacg aacaccggat aaatcaaatc
    27901 atcggcggtc agcgtgtgtt cgcgcatcag gcggcgtgaa aaatcgtccc tgcgcatacg
    27961 gcgcatacgc gaagccggaa cattgcggta aggaaactgc ataagccctc caatcatcct
    28021 gtcaacaatt caaaccatac ggaagccgcc gcaacttgca gacagcatcg ggcggcaatc
    28081 aaaatccgtt ttcaccggaa agggtttcgg cccgccgaaa tgccgcgccg aaggacggcg
    28141 tcccgcccat taaagaacaa tagcaaaaca acagcttcag gctgtcagcc ttcgatattc
    28201 ttacgccaca ataccaaaag tttcccgata tgctgaacag gttgcgcgtc aaccgcctca
    28261 cataaggcag tgcagatttc gatacgttcg gcacggtcgt cgccgaatac gcgcacttta
    28321 atcagctcat gcgccgtcaa tgccgcatcg gtttccttga tgaccgcgtc cgtcagaccc
    28381 tgctgaccga ccatcacaac aggatggaga tggtgcgcgc gcgctttcag ttccaaaatt
    28441 tctttggtgt tcaatttggt atccgtcatt ttcctactgc ttgaataaaa agaataatgc
    28501 ggcattgtac gcgatttggc acgacatcgg caaaattaac gtacaatacg cggtttccat
    28561 tccgacccgc gaaccactat ggctgtacgt tccaaatcct caaaagcgtg gctgcacgaa
    28621 cacgtcaacg accactacgt ccatatggcg caaaaagacg gctaccgcgc ccgtgccgca
    28681 tacaaacttt tggaaatcaa cgaaaaagac aaattaatca aacccggcac ggtacttgcc
    28741 gacttgggca gcgcaccggg aagctggtcg caggttgccg ccaagctgac gggtacttcc
    28801 ggagcagttt tcgccttgga catcctaccc atggaagcca tagggggcgt ctccttcatt
    28861 cagggcgact tccgcgagaa cgacgtactg gcacaattcg aaaccttgtt ggacaaccgc
    28921 ccgctcgacc ttgtaatttg cgatatggcg cccaatatgt cgggaaacgc cgtaagcgat
    28981 caggcacgca gcttttatct gtgcgaactg gctttagact tcgcctcgca acacctgaaa
    29041 accggcggca gctttttggt caaagtcttt cagggtgcag gctatcagga atacatggca
    29101 gccatgcgcg aaattttcgg cacggtgcag acgcgcaaac ccgaagcctc gcgcaatcgc
    29161 tccagtgaga tttatttatt gggcaaaaat aaacgctgac aatacagacg gcgtgcttta
    29221 caatcatttc cgttttacac ctcaattatg gagccttgct aagtggggaa cacctttaaa
    29281 tcaatccttg tctgggtcgc cttgggtatc ggcctgatgg ctgcgttcaa cgctttagac
    29341 ggtaaaaaag aagacaacgg gcaaatcgaa tattctcagt tcatccaaca ggtcaacaac
    29401 ggcgaagtat ccggcgtcaa catcgaagga tccgtcgtca gcggctacct gattaagggc
    29461 gagcgcaccg acaaaagcac cttcttcacc aacgcgcctt tggacgacaa cctgattaaa
    29521 acactgctcg acaaaaacgt ccgtgtaaaa gtaacgccgg aagaaaaacc gagcgcgctg
    29581 gctgccctgt tttacagcct gctgcccgtc ctgctgctga ttggcgcgtg gttctacttt
    29641 atgcgtatgc agacgggcgg cggcggaaaa ggcggcgcat tctcattcgg caaaagccgc
    29701 gcccgcctac tggacaaaga tgccaacaaa gttacctttg ccgatgtcgc cggctgcgac
    29761 gaagccaaag aagaagtgca ggaaatcgtc gattacctca aagcgccgaa ccgctatcaa
    29821 agcctgggcg ggcgcgtgcc gcgcggcatc ctgctggcgg gcagcccggg tacgggtaag
    29881 acgcttttgg cgaaagcgat tgcaggcgaa gccggcgtgc cgttcttcag catttcaggt
    29941 tccgactttg tcgaaatgtt cgtcggtgtc ggtgcaagcc gcgtccgcga tatgttcgag
    30001 caggcgaaga aaaacgcccc ctgcatcatc tttatcgacg agattgacgc agtcggccgc
    30061 caacgcggcg caggtttggg cggcggcaat gatgagcgcg agcaaacatt aaaccaattg
    30121 ttggttgaaa tggacggttt tgagagcaat cagactgtaa ttgtgattgc ggcaaccaac
    30181 cgccccgacg tactcgatcc tgcgctgcaa cgccccggcc gtttcgaccg ccaagtggtt
    30241 gtccccctgc cggacatccg ggggcgcgaa cagattttga acgtccattc taaaaaagtg
    30301 cctttggaca aatctgtgga tttattgtcc ctcgcgcgcg gcacgccggg tttttccggc
    30361 gcggatttgg cgaacttggt caacgaagcc gccctgtttg ccggccgccg caataaagtc
    30421 aaagtcgatc agagcgattt tgaagacgcc aaagacaaaa tctatatggg tccggaacgc
    30481 cgcagtatgg tgatgcacga agacgaaaaa cgtgcgacgg cgtatcacga atccggacac
    30541 gcgattgttg ccgaaagcct gccctttacc gaccccgtcc acaaagtaac cattatgccg
    30601 cgcggacgtg cgctgggtct gacttggcag cttccggagc gcgaccgcat cagtatgtat
    30661 aaagatcaga tgttgagcca gctctccatc ctgttcggcg gacggattgc cgaagacatc
    30721 ttcgtcggac gcatctccac cggcgcatca aacgactttg aacgcgcaac ccaaatggcg
    30781 cgcgaaatgg taacgcgcta cggcatgagc gacaaaatgg gcgtgatggt ttatgcggaa
    30841 aacgaaggcg aagtcttctt aggacgcagc gtaacccgtt cgcaaaacat ttccgagaaa
    30901 acccagcagg acatcgatgc ggaaatccgc cggattttgg acgagcagta tcagattgcc
    30961 tacaaaatcc tcgatgaaaa ccgcgacaag atggaaacga tgtgcaaagc cctgatggaa
    31021 tgggaaacca tcgaccgcga tcaggtactg gaaatcatgg cgggcaaaca acccagcccg
    31081 cccaaagatt acagccacaa cctgcgcgag aatgcggacg cggcggaaga taacgcgccg
    31141 cacgctccga ctcgggaaga aaccgaagca cctgccccgg cagacaccgc ttcgacagag
    31201 tccgagcagc agcctgaaaa caaggcttaa cttcccgaac aaacggcagc ccgcaagctg
    31261 ccgttttccc atcccgtttt cagacggcat tttccactca atgccgtctg aaacgccaaa
    31321 gccgtatcgg tttttacgaa tctgcgatat ggcggtttaa attgaaatca gaacggggca
    31381 aggctgtacc ggtttaaaat taaaccgcta taataccgcc cttcgaatac acgcccgcat
    31441 tggtgatgcc cgtgaaaaaa gttgaaaaaa acatcttggt gctgcacggc gcggacaaaa
    31501 tgttcgagct ggtcgacaag gttgaggatt acccgcactt tctgccgtgg tacagcaaga
    31561 ccgaagtcat cgggcgtagc ggcaacgaac tgaaggcgcg gctgtttatg gattatatgc
    31621 acgttcgcca atcgtttgcc acgcacaacc gcaacattcc gggcagggaa atccgtatgg
    31681 aactgctcga gggtccgttc aaaaccttac gtggaacgtg gaaatttatc gatttgggcg
    31741 acgatatgtg caaaatcgaa ttcaatttgg aatacgattt ttccaatgcc gttttgtccg
    31801 ccttaatttc ccccgtcttc aaccaccttt ccaccacgct ggtcgaagcg ttcgtcaaag
    31861 aggcagaccg ccgttatgct tgaaattgag attgtgtacg ggctgcccga ccgacaggtt
    31921 ttgaaaacca tgcagcttgc cgagggaaca accgtccgcg ccgccgcact gcaaagcggt
    31981 ttggacggca tatttgaaga tttaaacctg cattccgcgc ctttgggcat tttcggcaaa
    32041 gccgtcaaag acgacacgcc gctgcgcgac ggcgaccgca tcgaagtgta ccgcccgctg
    32101 ttgatcgacc ccaaagaagc gcgccgcaaa cgcgttcaaa atcaagaaga ataaccatgc
    32161 cgtctgaacc ccgtccggac ggcatctgat ggaaaacgac atgtcaaaca aaatcaaaat
    32221 ggttgtcggc ttgggcaacc cgggcaaaga atacgaacag acccgccata atgcaggctt
    32281 ttggttcctc gacgaactgg cttggaagtg gaaggcttcg tttaaagaag aaaaaaaatt
    32341 cttcggcgaa gtcgcccgtg ctaccctgcc cgacggcgat gtctggctgc tcaagccgac
    32401 cacgttcatg aaccgttccg gacaggcagt tgccgccctt gcgcagtttt ataaaatcaa
    32461 acccgaagaa atcctcgtcg tccacgacga actcgacatt ccctgcggac ggatcaaatt
    32521 caaactcggc ggcggcaacg gtggacacaa cggcttgaaa gacattcagg cacggctcgg
    32581 cacggccgac tattaccgtc tgcgcctcgg tatcggccat ccgggcgacc gcaacctcgt
    32641 cgtcggctat gtcctgaaca aacccagtac ggaacaccgc cgacagattg acgatgccgt
    32701 cgccaaatcc ctgcaagcca tacccgacat ccttgccggc aaatgggaag aagcaacacg
    32761 tttcctgcac agcaaatgac ccaatgccgt ctgaagccct ttcagacggc attcccgcca
    32821 tcagcgagaa cccgcactat gtccgaactc aaccggctca tccaaaccga atccgttgcc
    32881 gtcattgaag aaactttaaa ttttctgctc tacgaatgca gcatagacga tgccccctcc
    32941 gccgaagaaa ttgccgtttg gcgcgatatg ctggccgcac gcggcggaaa attcctgcgc
    33001 ctatccaaac tatgccagac atggcttgaa gaggaacaag catgaatctg ccacgcaacc
    33061 gctttatcct gctctcggca ttgtggtttg caggcagcat ttactcactg cttttcaaag
    33121 ctgccgaaac cgcgccaccg ccttttccgc attttgacaa agtggcgcac ctcgccctgt
    33181 ttttcgcaca aatctggctt ctgaccaaag cattcagaac cgacaaccgc cccatcccct
    33241 atcgcagcct gatggtcttt gccctctgtt tcgccctctt cagcgaatgc gcgcaggcat
    33301 ggtttaccgc aacgagaacc ggcagtttgg gcgatgtcct tgccgacctg acgggcgcag
    33361 cccttgccct ctttaccgcg cgagctgcct gccgccctga ctaaatcggt ttattttccc
    33421 caaacaggat gcacctcttc ccgatatatc ctatttttcc ccttacatat caatcccatc
    33481 tcataaacaa aaccgacaaa tcgtttacaa tatatttaca ctacatcaga ttacaaatat
    33541 actcgaacca gttgcagaag cggcgattcc acaaaccgtt tcggattgca cgacacaaaa
    33601 gaaaaaccga ttttgttgcc ttaaaggagt attcatgaac ctgcatgcaa aggacaaaac
    33661 ccagcatccc gaaaacgtcg agctgctcag tgcgcagaag ccgattaccg actttaaggg
    33721 cctgctgacc accattattt ccgccgtcgt ctgtttcggc atttaccaca tcctgcctta
    33781 cagccccgat gccaataaag gtatcgcgct gctgattttc gttgccgcac tttggtttac
    33841 cgaggccgtc cacattaccg taaccgcact gatggtgccg attctcgccg tcgtactcgg
    33901 tttccccgac atggacatca aaaaggcgat ggctgatttt tccaacccga ttatctacat
    33961 ttttttcggc ggcttcgcgc ttgccaccgc cctgcatatg cagcggctgg accgtaaaat
    34021 cgccgtcagc ctgttgcgcc tgtcgcgcgg caatatgaaa gtggcggttt tgatgttgtt
    34081 cctcgttacc gcctttctgt ccatgtggat cagcaacacc gccaccgccg cgatgatgct
    34141 gcctctagca atgggtatgc tgagccacct cgaccaggaa aaagaacaca aaacctacgt
    34201 cttcctcctg ctcggcatcg cctattgcgc cagcatcggc ggcttgggca cgctcgtcgg
    34261 ctcgccgccc aacctgattg ccgccaaagc cctaaatctg gacttcgtcg gctggatgaa
    34321 gctcggcctg ccgatgatgc tgttgattct gcccttgatg ctgctctccc tgtacgtcat
    34381 cctcaaacct aatttgaacg aacgcgtgga aatcaaagcc gaatccatcc cttggacgct
    34441 gcaccgcgtg atcgcgctgt tgattttcct tgccacagcc gccgcgtgga tattcagctc
    34501 caaaatcaaa accgccttcg gcatttccaa tcccgacacc gttatcgccc tgagtgccgc
    34561 cgtcgccgtc gtcgtcttcg gcgtggcgca atggaaggaa gtcgcccgca ataccgactg
    34621 gggcgtgttg atgctcttcg gcggcggcat cagcctgagc acgctgttga aaacatccgg
    34681 cgcgtccgaa gccttgggac agcaggttgc cgccaccttt tccggcgcgc ccgcattttt
    34741 ggtgatactc atcgtcgccg ccttcattat ttttctgacc gagttcacca gcaacaccgc
    34801 ctccgccgca ttgcttgtac cgattttctc cggcatcgct atgcagatgg ggctgcccga
    34861 acaagtcttg gtattcgtca tcggcatcgg cgcatcttgt gccttcatgc tgccggttgc
    34921 cacaccgcct aacgcgattg tgttcggcac gggcttaatc aagcaacgcg aaatgatgaa
    34981 tgtcggcata ctgctgaaca tcctctgcgt agtattggtt gctctgtggg cttatgctgt
    35041 actgatgtaa accatcgacc taaacaacaa gaccgtctga aagaatattt ttcagacgac
    35101 cttgaagttt gtcgttcaga cacaatttgt cgaatcattc aaaaccagat tctaacgaaa
    35161 ggaaacccat gattatcctg cacaccaaca aaggcgacat caaaatcgaa ctcgatttcg
    35221 acaaagcccc tgttaccgcc aaaaacttcg agcaatacgt caaagacggc ttctacgacg
    35281 gcgtaatctt ccaccgcgtc atcaaaggct tcatgattca aggcggcggc atggatgaaa
    35341 acatgaacga aaaagaaacc cgcgatccga ttcaaaacga agcgtccaac ggcctgccca
    35401 acgataaata caccatcgcc atggcacgca cttccgaccc ccattccgcc agcgcgcaat
    35461 tcttcatcaa cactgccgac aacgctttcc tgaacttccg ttctaaagag ctgtacggca
    35521 aaaccgtcgt ccaagactgg ggctatgccg tattcggtaa agtcgttgac ggttttgacg
    35581 ttgtcgatgc catcgaaggc gtttctacca aacgtcatgg ttaccacgac gacgtaccga
    35641 gcgaacctgt cgtcatcatt aaagccgaag cggtataaac cgacaatccg aaagcagcct
    35701 gcacaaaggc tgcttttatt tcagacggca tgttatttga tgtaaccgtg ctatgccgtc
    35761 tgaaaaccgg acgcaagcct tcagacggca taccgctatg ttaaaatatg cccgtttttc
    35821 ctaaacggac acaaaggaaa ccttatggca agcatcgccc gcgacatctt caaagcctac
    35881 gacatccggg gtattgtcgg caaaaccctg accgacgaag ccgcctacct tatcggcaaa
    35941 gccatcgccg ccaaagccgc cgaaaaaggc attacccgca tcgcgctcgg acgcgacgga
    36001 cgcttgagcg gtcccgaact gatggaacac atccggcgcg gctttaccga cagcggcatc
    36061 aatgtcctca atgtcggtat ggttgccact cctatgctct acttcgccgc cgtcaacgaa
    36121 tgcggcggca gcggcgtgat gattaccggc agccacaatc cgcccgatta caacggcttt
    36181 aaaatgatgc tcggcggcga cacgcttgcc ggcgaagcca tccaagaact tttgtccatc
    36241 attgaaaaag acggttttgc tgccgccggc aaacaaggca gcgtcaccga aaaagacatc
    36301 tccggcgaat acctcaaaca cattaccgga cacatcaaac tcaaacgccc catgaaaatc
    36361 gccatcgacg caggcaacgg cgtaggcggc gcattcgcag gcaaactcta caaaggcttg
    36421 ggcaatgaag ttaccgaact tttctgcgaa gtggacggca acttccctaa tcaccacccc
    36481 gacccttcca aaccgaaaaa cctgcaagac ctcatcgtcg agctcaaaaa cggcgaggcc
    36541 gaaatcggct tagcatttga cggcgatgcc gaccgcttgg gcgtggttac caaagacggc
    36601 aacatcatct atccggaccg ccaactgatg cttttcgcgc aagacgtgtt gagccgcaat
    36661 cctaaagcca aagtgatttt cgacgtcaaa tccacccgtc tgcttgcgcc ttggattaaa
    36721 gaacacggcg gcgaacctgt gatggaaaaa accggccaca gctttatcaa atccgccatg
    36781 aaaaaaaccg gcgcgccggt tgccggcgaa atgagcggac acatcttctt caaagaacgc
    36841 tggttcggct tcgacgacgg tctgtacgcc ggcgcacgcc tcttggaaat cctgtctgcc
    36901 tccgataatc cgtccgaagt gttaaacaac ctgccgcaaa gcatttccac gcccgaactc
    36961 aacatcgccc tgcccgaagg cagcaacggc catcaggtta tcgacgaact cgccgccaaa
    37021 gccgaatttg aaggcgcaac cgaaatcatc accatcgacg gtctgcgcgt tgaatttccc
    37081 gacggcttcg gtctgatgcg tgcttccaat accacgccga ttctggtgtt gcgttttgag
    37141 gcggatacgc aagaagccat cgagcggatt caaaaccaat tcaaagccgt catcgaaagc
    37201 aatccgaatc taatctggcc tctgtaaaca caggaaaaat gcttaatcaa atcttggtag
    37261 attggatttg gcttaaaaat ctccgcgtcc gttcgtgttt ggggtggtcg aacaactctt
    37321 tcgggctgcc ctgctctacg ataacgccgc cgtccatcac gacaacggtc gtggcaactt
    37381 ccagcgcgaa cttgatttcg tgggtaacga cgaccatcgt ccaaccttcc cgcgccaatt
    37441 ccttcatggc gttcaacacg tcttgcacca attcagggtc gagtgcggaa gtgggttcgt
    37501 caaacaacat cagctcgggc tgaatcgcca atgcgcgggc aatgccgacg cgctgctgct
    37561 gaccgccgga aagctggtag ggatacaaat ccactttgtc gcccaagccg actttttcca
    37621 gcagtttcag agcctcttcg cgcgcttggg cggcaggctt gccctgtacg gcaaccggtc
    37681 cttccattac gttttccaag gcggttttgt gcggaaagag gttgtattgt tgaaacacca
    37741 tgcctgattt gcggcgcagt gccaaaatat cgtgtttgct tggtttttta gaaaaatcga
    37801 ttttcagcgg tcgctcgttg tcgaactcga tttgtccgtc ttcgggcatt tccaacgcgt
    37861 ttaggcatcg cagaaacgtc gttttgcctg agccggaagg cccgaggata acgaccacct
    37921 gccctttgcc cacatccaaa ttgatgccgc gcaaaatagt gctttcgccg aaggtcttat
    37981 ggatattgcg gattttaatc ataacaactc cttatttggc gacataacgg tcgaaacgtt
    38041 tttccaaacg tgcctgaatc aggaacagaa ccttgcaaaa acaccagtaa accaaagcgg
    38101 cttcgatata gacgggcaaa aagtcataag tgcggtttgc cgtttcctgc gcgacgcgga
    38161 ataattccgt taccgtcacg actgccgcga gcgaggtgtt tttaaacaaa ccgataaact
    38221 cgttgctcaa aggcggcacg gcaacgcgaa atgcctgcgg cgcgacgatg cggcggaacg
    38281 tctgcatata ggtcataccg atggagaaac ctgcttccca ttggccttta ggtacggaca
    38341 aaattgccgc gcgtatggtt tcggaagcgt atgcaccgac attgagcgag aagccgataa
    38401 tggcggcggg aatcggatcg atatagatac cgacggacgg cagcccgtaa aacacaatca
    38461 caagctgcac caacagcggc gtaccgcgaa tgacggaaat ataaaattcc accaatttca
    38521 gcaggatttt ccgcgcaatg ccgccggcgg gcataatccg caccaaagcc acggctacgg
    38581 caataaccat accgataacg aaagaagctg ccgccaaagg cagagacacc gcgaagccgg
    38641 ctttgaccat aggcaaaaac gcgctgacaa tcatatcggc gcgtgtttcc gtcataaacg
    38701 gcagcgaagc aaggaaatta ttgaacactg atgtcttttc cgaagaattg ttcgcccagt
    38761 tttttcagcg taccgtcggc tttcagctcg ttgattgccg tactgaattt cgccacggct
    38821 tcgtcattgc ccttgttgac aatcaggccg gaaccgactt tttcatcggc aggtgcggac
    38881 caaacgattt tcacgcccgc attcgggttt ttcttcagat agtccaaaac cgccaattcg
    38941 tcgttcaggg ttgcatcggc acgtttttgt tcaatcaggg tcagcgattg cgccaaaccg
    39001 tccactgcca ccaaatctgc gcctgcagct ttggcttttt cgccgtagtt gctggtcagg
    39061 gattgtgcgg ttttcacgcc tttgatgtcg tcgatagatt tgatgttgct gtcgttacgg
    39121 gcaaccaata cggcaccgct ccagctgtaa ggatcggatt tgtcgaatgt cgcttggcgt
    39181 tcggggctgg tcagaccgac ttggtttgcc accacgtcga aacgccccgc cttcaaaccc
    39241 gccatcatcg aatcccattg cgtttcttta aactcgactt tcacgcccag tttttccgcc
    39301 acggcgcggg ttacttccac atcgtaaccg gtcagtttgc cgtccttgtc gtggtaggta
    39361 aacggtgcgt aagtgccttc cgtgccgacg gtaaccgtgc ctttattgtt gatgcgctcg
    39421 attaaagaac cggaaactgc cgattgtgca ggcgcggaag atgctccgct gccgccttcc
    39481 gaaccgccgc aggccgccaa aaccaatgcg gcaataccgc cgagtacgaa ttttttcaac
    39541 atcatcctct cctgtaaaaa gtgtgcaagt gcggcattct aagtgaaatt gcggcaaaca
    39601 caaagaatcc tttttttata tggttattcc aaatcggaat ggaaaagata tgccgaagcc
    39661 gccggaagcg gaaataaagg gggcgggaaa ggcggtgggc ggcacgaaac cgaaaagcgg
    39721 catcaggtat gcaaacggcg gattcacgca cgccgttccg gcaaaaatcc gcctgccgat
    39781 tcggtgctat aatccatccg aaacagatga caccaaaaag gaacatctca tgaacacgcc
    39841 ccaatccgcc atcattcccg accacgccca agccggcatc tttatcgaag ccgacttcgc
    39901 cgccaaccgc ctcaacgata ttaaagccgc ctgccgcgct tcgctcgacg cgttaactgc
    39961 cttgaaagcc cgctttccgg acgatatttt gggtctgacc atcgccttcg gcagcaaagc
    40021 ctgggcaaca ttcggacata cggacgaagg cagtgaaatc aaacccttct ccgaaatggg
    40081 caacgggctt gcgccgtcca cgcagcacga tatgtccatc cacatccaat ccttccgcca
    40141 aaacgccgcc tacgcgcttg cccaatccgt tttgggcgcg ttcggcgaca gcatatgcgt
    40201 cgcgtccgaa gaacacggtt tgcgcctgta tcaggatcgc gggctggacg gtttcgtcga
    40261 cggcacggaa aacccgcagg gcgatgaaaa tgtccgcgaa gtcgccatca tccccgaagg
    40321 aaaacccgat gcgggcggca gctatgtcct gctgcaaaaa tacctgcacg atttgaaaaa
    40381 atgggatgcc gtccccgtcg ccgaacagga ggcctcggtc ggacgcggca aggaaaccga
    40441 cgacgaattc ggccgcgatg tccgcctgcc cgattcgcac ctcggccgcg tcaacctgaa
    40501 agaaaacgga gtcggcctga aaatcgtccg ccgcagcctg cccttcggca aaatcagcgg
    40561 cgaacacggt ttgatgttta ccgcatactg ccgcacgctg cacaatatcg aagcgcaatt
    40621 attgagtatg ttcggcgata cggacggcaa aaccgacctg ctgctccgac acctctccgc
    40681 cgccgtttcg ggcggatact actacgcgcc gtctgtcgaa cgcctgcaaa acctctaagc
    40741 cggacgatgc cgtctgaaac catttttcag acggcatttt ccc
//
LOCUS       DAXIDM010000005        40170 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000005 DAXIDM010000000
VERSION     DAXIDM010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 40170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40170
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.005"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(195..285)
                     /locus_tag="ACFOAE_000182"
     tRNA            complement(195..285)
                     /locus_tag="ACFOAE_000182"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(249..251),aa:Ser,seq:gga)
     gene            complement(321..407)
                     /locus_tag="ACFOAE_000183"
     tRNA            complement(321..407)
                     /locus_tag="ACFOAE_000183"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(371..373),aa:Leu,seq:cag)
     gene            complement(443..529)
                     /locus_tag="ACFOAE_000184"
     tRNA            complement(443..529)
                     /locus_tag="ACFOAE_000184"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(493..495),aa:Leu,seq:cag)
     gene            618..2993
                     /gene="rnr"
                     /locus_tag="ACFOAE_000185"
     CDS             618..2993
                     /gene="rnr"
                     /locus_tag="ACFOAE_000185"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFC6883759.1"
                     /translation="MNKNIKSLNLREKDPFLSREKQRYEHPLPSREWIIELLERKGVP
                     SKIESLARELSITEDEYVFFERRLKAMARDGQVLINRRGAVCAADKLDLVKCRVEAHK
                     DGFGFAVPLTPAKDGDFVLYERQMRGIMHGDIVTVRPAGMDRRGRREGTVLDIVERAQ
                     SKVVGRFYMDRGVAILEPEDKRLNQSIVLEPDGVARFKPESGQVIVGEIEVYPEQNRP
                     AVAKIIEVLGDYADSGMEIEIAVRKHHLPHQFSEACAKAVKKIPDHVRKSDLKGRVDL
                     RDLPLVTIDGETARDFDDAVFAEKIGRNYRLVVAIADVSHYVRPDDAIDTDAQERSTS
                     VYFPRRVIPMLPENLSNGICSLNPNVERLCMVCDMVITYAGNIKEYRFYPAVMRSHAR
                     LTYNQVWKWLSGGIGHPFKAQIDTLYKLFKILQKKRFERGAVEFDSIETQMLFDDNGK
                     IEKIVPVVRNDAHKLIEECMLAANVCAADFLLKNKHTALFRNHLGPTPEKLAALREQF
                     GLLGLQLGGGDNPSPKDYAALAGQFKGRPDAELLQVMMLRSMQQAVYEPHCDGHFGLA
                     YEAYAHFTSPIRRYPDLTVHRAIKAVLNQQTYTPKKSWQALGVHTSFCERRADDASRD
                     VENWLKTYYMRDKVGEIFEGKISGVANFGIFVTLDDIHIDGLVHISDLGEDYFNFRPE
                     IMAIEGERSGIRFNMGDRVAIKVARADLDDGKIDFVLIAEGSGRGRKVKSSASAKPAG
                     TAGKGKPKTAAGKKTARGGKVRGRGASAAAESGKKAKKPVPIKVKKRKGKS"
     gene            complement(2988..3185)
                     /locus_tag="ACFOAE_000186"
     CDS             complement(2988..3185)
                     /locus_tag="ACFOAE_000186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883760.1"
                     /translation="MPSERRLRPVCRIPLAFKTAVEINAIFQYGRFDWPEMMRRPPYQ
                     KIGRRLRESMPLPPQAAPSAL"
     gene            complement(3332..4795)
                     /gene="guaB"
                     /locus_tag="ACFOAE_000187"
     CDS             complement(3332..4795)
                     /gene="guaB"
                     /locus_tag="ACFOAE_000187"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003767939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFC6883761.1"
                     /translation="MRIVEKAYTFDDVLLVPAHSTVLPRDVKLQTKLTREITLNLPLL
                     SAAMDTVTEARLAISMAQEGGIGIIHKNMPPEMQARAVSKVKRHESGVVKDPVTVAPT
                     TLIREVLEMRAQRKRKMSGLPVVENGKVVGIVTNRDLRFENRVDLPVSAIMTPRERLV
                     TVPEGTSIDEARELMHTHKVERVLVLNEKDELKGLITVKDILKTTEFPNANKDSEGRL
                     RVGAAVGTGGDTEERVKALVEAGVDVIVVDTAHGHSQGVIDRVKWVKETYPHIQVIGG
                     NIATAKAALDLVAAGADAVKVGIGPGSICTTRIVAGVGVPQLTAIHNVAEALKGTGVP
                     LIADGGIRFSGDIAKALAAGAYSVMLGGMFAGTEEAPGEIELYQGRSYKSYRGMGSLG
                     AMSQGSADRYFQDKTDSADKYVPEGIEGRVPYKGPIVNIIHQLTGGLRSSMGYLGCAN
                     IAEMHEKAEFVEITSAGMSESHVHDVQITKEAPNYHR"
     gene            complement(4942..7500)
                     /gene="glnD"
                     /locus_tag="ACFOAE_000188"
     CDS             complement(4942..7500)
                     /gene="glnD"
                     /locus_tag="ACFOAE_000188"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0018177 - protein uridylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="HFC6883762.1"
                     /translation="MPANLSSALETFKQQRDAAEAHYLKANRVSVFFREYTAAVETLL
                     AALWAEYFQNSALCLMAVGGFGRGELYPCSDVDLAVVSPAPLSDGIQEQIARFVQTLW
                     DCKLMPSVKSGSVDELCESVRNDITGDTAFLEARFLFGNRQTADELAKKMNAQRNVPA
                     FVEAKLVEMEHRHAKSQGSGAVLEPNIKSCPGGLRDIHTLLWIAKAQGLATNLPDLLK
                     QRILTRAEAGMLSHGYRRLAHIRIHLHLNANRAEDRLLFDLQPQVAESMGYEGLNLRR
                     QSEELMRVFYRAIKTVKQLGGILTPMLQSRVSSTPLRVTLRIDDDYIQVNNQIAARHT
                     DIFFRRPEHIFKIVEIMQQRNDITALEPQTLRAWWGATRKINRSFYQNSENRHRFAGF
                     FRNGNGLTQTLRFLNLYGVLGRYLPAWEKIVGLLQHDLFHIYPVDDHILTVVRNVRRL
                     ALDMHSHELPYASALMQSFEKQDILYLAAFFHDIAKGRGGDHAIQGIADARQFAADHF
                     LTEEESDLLAWLVENHLLMSTVAQKEDIQDPSVLDAFCKRVQTHERLSALYFLTISDI
                     RGTNPKLWNAWRASLLESLFHAAGRYLTGNGGNPHTLFGRRRQEAADLLTRAAVPEKQ
                     QKKLWNALGSAYFARHQSREILWHAANLVHDFETPIVRSRILPKSDSFQVMVFMPNGP
                     RLFARLCRIFSRHGFDILAARAFITEHDYILDTFIVQIPSQHAPEDYPDIQSALEAEL
                     NNFIHGHTVAEISSHSRRISRRSRYMPIAPSITITPEEDYPDWYSVEITAVNRPFLLA
                     DMAEVFFAHNVSLRYAKISTLDERAEDSFTVFSPDLKNPKIQSSLKQALLEQLA"
     gene            complement(7549..7869)
                     /locus_tag="ACFOAE_000189"
     CDS             complement(7549..7869)
                     /locus_tag="ACFOAE_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC6883763.1"
                     /translation="MMGNKLTLPAELPDEQDLRAVLAYNMRLFRVNKGWSQEELARQC
                     GLDRTYVSAVERKRWNIALSNIEKMAAALGVAAYQLLLPPQERLKLMTNSADTRQMPS
                     ESGI"
     gene            complement(8194..8667)
                     /gene="bfr"
                     /locus_tag="ACFOAE_000190"
     CDS             complement(8194..8667)
                     /gene="bfr"
                     /locus_tag="ACFOAE_000190"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HFC6883764.1"
                     /translation="MKGDRLVIRELNKNLGLLLVTINQYFLHARILKNWGFEELGEHF
                     FKQSIVEMKAADDLIERILFLEGLPNLQELGKLLIGESTEEIIACDLEKEKEKHEALI
                     AAISVAEAQQDYVSRDLLEKQKDTNEEHIDWLETQQELIGKIGLPNYLQTAAQED"
     gene            complement(8695..9159)
                     /gene="bfr"
                     /locus_tag="ACFOAE_000191"
     CDS             complement(8695..9159)
                     /gene="bfr"
                     /locus_tag="ACFOAE_000191"
                     /EC_number="1.16.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004322 - ferroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA];
                     GO_process: GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HFC6883765.1"
                     /translation="MQGNQAVVDYMNELLSGELAARDQYFIHSRLYSEWGYTKLFERL
                     NHEMEEETTHAEDFIRRILMLGGTPKMARAELNIGTDVVSCLKADLQTEYEVRDALKK
                     GIKLCEEAQDYVTRDLMVAQLKDTEEDHAHWLEQQLRLIELIGEGNYYQSQL"
     gene            complement(9622..10605)
                     /gene="lipA"
                     /locus_tag="ACFOAE_000192"
     CDS             complement(9622..10605)
                     /gene="lipA"
                     /locus_tag="ACFOAE_000192"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016992 - lipoate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HFC6883766.1"
                     /translation="MSEIKTDDPKRGIKLRGADKTARIPIKVVPLQEKLKKPEWIRAK
                     LPSRKFFEIKDILREQKMHTVCEEASCPNIGECFSKGTATFMIMGDICTRRCPFCDVG
                     HGRPNMLDPDEPRNLAESVKAMNLRYVVITSVDRDDLRDGGAQHFADCIKAIRETSPN
                     TKIEILVPDFRGRLDIALKILAETPPDVMNHNLETHPSLYKKARPGANYQHSLDLLKR
                     YKEMMPHIPTKSGIMVGLGETDEDVREIMRDMRAHNIEMITIGQYLQPSDGHLPVLRY
                     VTPEQFKIFEKEAYELGFSNAAIGAMVRSSYHADEQAAEALRESHGGCGHH"
     gene            complement(10598..11221)
                     /gene="lipB"
                     /locus_tag="ACFOAE_000193"
     CDS             complement(10598..11221)
                     /gene="lipB"
                     /locus_tag="ACFOAE_000193"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033819 - lipoyl(octanoyl) transferase
                     activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HFC6883767.1"
                     /translation="MKIIHKGLVEYLPTFEAMKTFNAGRNADTEDELWVVEHPPVFTQ
                     GLAGKPEHLLIRDDIPVVQIDRGGQITYHGPGQLVVYTMIDFKRRKTSVRNIVSALEN
                     SIIATLAEYGIEAAADPKRPGVYVGERKIASLGLRIKNGSVYHGLALNVNMDLSPFTH
                     INPCGYAGMEMTQIADFVQPCPTPDEVAAKLTAHLETQFTPKADNNE"
     gene            complement(11223..11498)
                     /locus_tag="ACFOAE_000194"
     CDS             complement(11223..11498)
                     /locus_tag="ACFOAE_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HFC6883768.1"
                     /translation="MTEQKNKTSLIEFPCTFPLKVMGAVHPEFEQAVLDTVRLHAPDT
                     QAHHITTRPSSKGNYTGATVQVKVENQEQLDNIYRALTSHELVKVVL"
     gene            11683..12753
                     /locus_tag="ACFOAE_000195"
     CDS             11683..12753
                     /locus_tag="ACFOAE_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFC6883769.1"
                     /translation="MYRRKGRGIKPWMGAGAAFAALVWLVFALGDTLTPFAVAAVLAY
                     VLDPLVEWLQKKGLNRASASMSVMVFSLILLFALLLIIVPMLVGQFNNLASRLPQLIG
                     FMQNTLLPWLKNTIGGYVEIDQASIIAWLQAHTGELSNALKAWFPVLMRQGGNIVSSI
                     GNLLLLPLLLYYFLLDWQRWSCGIAKLVPRRFAGAYTRITGNLNEVLGEFLRGQLLVM
                     LIMGLVYGLGLVLVGLDSGFAIGMVAGILVFVPYLGAFTGLLLATVAALLQFGSWNGI
                     LSVWAVFAVGQFLESFFITPKIVGDRIGLSPFWVIFSLMAFGQLMGFVGMLAGLPLAA
                     VTLVLLREGVQKYFAGSFYRGR"
     gene            complement(12859..13806)
                     /locus_tag="ACFOAE_000196"
     CDS             complement(12859..13806)
                     /locus_tag="ACFOAE_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stomatin-like protein"
                     /protein_id="HFC6883770.1"
                     /translation="MEFFIILLAAVAVFGFKSFVVIPQQEVHVVERLGRFHRALTAGL
                     NILIPFIDRVAYRHSLKEIPLDVPSQVCITRDNTQLTVDGIIYFQVTDPKLASYGSSN
                     YIMAITQLAQTTLRSVIGRMELDKTFEERDEINSTVVAALDEAAGAWGVKVLRYEIKD
                     LVPPQEILRSMQAQITAEREKRARIAESEGRKIEQINLASGQREAEIQQSEGEAQAAV
                     NASNAEKIARINRAKGEAESLRLVAEANAEAIRQIAAALQTQGGADAVNLKIAEQYVA
                     AFNNLAKESNTLIMPANVADIGSLISAGMKIIDSSKTAK"
     gene            complement(13821..14228)
                     /locus_tag="ACFOAE_000197"
     CDS             complement(13821..14228)
                     /locus_tag="ACFOAE_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFC6883771.1"
                     /translation="MTVWFVAAVAVLIIELLTGTVYLLVVSAALAGSGIAYGLTGSTP
                     AAVLTAALLSALGIWFVHAKTAVRKVETDSYQDLDAGQYVEILRHTGGNRYEVFYRGT
                     HWQAQNTGQEELEPGTRALIVRKEGNLLIIAKP"
     gene            14309..14968
                     /gene="ung"
                     /locus_tag="ACFOAE_000198"
     CDS             14309..14968
                     /gene="ung"
                     /locus_tag="ACFOAE_000198"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFC6883772.1"
                     /translation="MDTWHDALGGEKQQPYFQEILNAVRQERLSGQIIYPPAADVFNA
                     FRLTAFDRVKAVILGQDPYHGAGQAHGLAFSVRQGIRIPPSLLNIYKELETDIEGFSI
                     PAHGCLTAWAEQGVLLLNTVLTVRAGQAHSHALLGWERFTDTVIRQLATHRKHLVFML
                     WGGYAQQKRKLIDSQNHLILTAPHPSPLSAYRGFFGCRHFSQANSYLSRHGIDPINWK
                     L"
     gene            15116..16232
                     /locus_tag="ACFOAE_000199"
                     /pseudo
     CDS             15116..16232
                     /locus_tag="ACFOAE_000199"
                     /inference="COORDINATES: protein motif:HMM:NF014442.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            16220..16534
                     /locus_tag="ACFOAE_000200"
     CDS             16220..16534
                     /locus_tag="ACFOAE_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HFC6883773.1"
                     /translation="MVHLSEIAAQDYNLNLPRYIDSGEVEDLQNLAAYLYGGIPAHDM
                     DALEAYWQVLGRMKNELFAEHDGRFTTIQRNRLQIFPTLNSLKSCGIGVEFRANLVQP
                     QI"
     gene            16576..17520
                     /locus_tag="ACFOAE_000201"
     CDS             16576..17520
                     /locus_tag="ACFOAE_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFC6883774.1"
                     /translation="MAHPDYAAFKAGHLAKFAAWHTQNDLAAIQPGRLIRKWSESLLD
                     AFKPGSLIEEYDFYQILTDYWAETLQDDVYLIAQDGWKAVKNLAEITKESDEDANLTV
                     VFEETETGKKGKAKTKRISKKYRSEVIAPELVARRYFSDGIAKLEEKQSELERLSQEL
                     ENHIEEHGGEEGALNDVLDAKGKLSAKLLKTALEESGIEEGERAVLQTTQTLMTQEKA
                     AKDAVKTQIEALNLAVFKQFGRLSEAEIKQLAVQDKWLADLQSRIENRLENSIQQLIS
                     RLNTLEDRYRSPMAELAREVEKWQSKVNAHLENMGFGG"
     gene            17671..17796
                     /locus_tag="ACFOAE_000202"
     CDS             17671..17796
                     /locus_tag="ACFOAE_000202"
                     /inference="COORDINATES: protein motif:HMM:NF013980.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883775.1"
                     /translation="MLERHRNARFMAHMDNFLPNWQSIKQQLNALELFAQIYNLT"
     gene            complement(18086..18601)
                     /locus_tag="ACFOAE_000203"
     CDS             complement(18086..18601)
                     /locus_tag="ACFOAE_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883776.1"
                     /translation="MKSKLPLILINFSLISSPLGANAAKIYTCTINGETVYTTKPSKS
                     CLSTDLPPIGNYSSERYIPPQTSEPTPSPSNGGQAVKYKAPVKTVSKPAKSNTPPPQQ
                     APSNNSRRSILETELSNERKALVEAQKMLSQARLAKGGNINHQEINALQSNVLDRQQN
                     IQALQRELGRM"
     gene            complement(19067..20989)
                     /locus_tag="ACFOAE_000204"
     CDS             complement(19067..20989)
                     /locus_tag="ACFOAE_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFC6883777.1"
                     /translation="MIEIKNLTLQRGLKVLLDKANATVNPGHRVGLIGKNGTGKSSLF
                     ALIKGKITQDGGDVSIPKNWRLASVSQETPDLDISALDYVLQGDAELQAFQTALRQAE
                     AQNDGMKQAEYHAKLEEIDAYTAPARAAKLLNGLGFSQEEHSRPVKSFSGGWRMRLNL
                     AQALICRADLLLLDEPTNHLDLETVLWLENHLASLPCTQIIISHDRDFLNAATTQTIE
                     LSQQKFTQYGGNYDFYQNERAQRLAQQQAAYVKQQAQIKHLQSFIDRFKAKATKAVQA
                     QSRMKALAKLERVAPAHLDSEFSFEFYHPDHLPNPLLKLEHADLGYEGKTVLHDITLS
                     LESGARYGLLGVNGSGKSTFIKALAGKIDLLSGSIVRSEKLNIGYFAQHQLDTIRADQ
                     NPVWHIQQLSPEVREQEIRNFLGGFNFVGDMALQKTEPFSGGEKARLALAMIIWQKPN
                     LLLLDEPTNHLDLDMRHALTLALQSFQGALIAVSHDRSLLEATTDSFLLIDKGRLKNF
                     DGDLNDYRQWRLAQENAAAAPAASAQSQSRKDTKRIEAQIRQEKARRGKPIQQKIDRA
                     EKEMAQLSEIQTACEAFLAQEDAYLEANKEKLQNTLSLLTKVKTQLAQIEEVWLACQE
                     ELERIETEIEKQFAER"
     gene            complement(21066..21437)
                     /locus_tag="ACFOAE_000205"
     CDS             complement(21066..21437)
                     /locus_tag="ACFOAE_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mth938-like domain-containing protein"
                     /protein_id="HFC6883778.1"
                     /translation="MLFEENPIDGHFTEYGHRSGEIRLAGQSFHKPVLVHKDSVCLSQ
                     CRTLSDLTPENLLSDIKPVDYPEILIIGTGAAQEFIHPKIMADFSRIGIGVECMNTDS
                     AFRTLVFLHSEGRRAWAWLQP"
     gene            21634..22941
                     /locus_tag="ACFOAE_000206"
     CDS             21634..22941
                     /locus_tag="ACFOAE_000206"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HFC6883779.1"
                     /translation="MKPVNIGLLGLGTVGGGTAAVLRDNAAEISRRLGREIRISAVCD
                     LSEEKARQTCPSAAFVKDPFELVAREDVDVVVELFGGTGIAKDAVLKAIENGKHIVTA
                     NKKLLAEYGNEIFPLAEKQNVIVQFEAAVAGGIPIIKALREGLAANRIKSIAGIINGT
                     SNFILSEMREKGSAFADVLKEAQALGYAEADPTFDIEGNDAGHKITIMSALAFGTPMN
                     FSACYLEGISKLDSRDIKYAEELGYRIKLLGITRKTGKGIELRVHPTLIPESRLLANV
                     NGVMNAVRVNADMVGETLYYGAGAGALPTASAVVADIIDIARLVEADTAHRVPHLAFQ
                     PAQVQAQTILPMDEITSSYYLRVQAKDEPGTLGQIAALLAQENVSIEALIQKGVIDQT
                     TAEIVILTHSTVEKHIKSAIAAIEALDCVEKPITMIRMESLHD"
     gene            22934..23368
                     /locus_tag="ACFOAE_000207"
     CDS             22934..23368
                     /locus_tag="ACFOAE_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883780.1"
                     /translation="MTEPKHEMPTEEQVAARKKAKAKIRTIRIWAWVILALLALTALL
                     SQCAMSKPQAKQKIVESCVKNIPFAEKWQNDLRARGLDSNNTRLAVDYCKCMWEQPLD
                     RLSEKQIRSFGKLGAQEQLDLLGGANAFEARDKQCVADLKSE"
     gene            complement(23427..23696)
                     /locus_tag="ACFOAE_000208"
     CDS             complement(23427..23696)
                     /locus_tag="ACFOAE_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007342959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFC6883781.1"
                     /translation="MNKSELIEAIAQEADISKAAAQKALDATTNAVTTALKQGDTVTL
                     VGFGTFYVGERAERQGRNPKTGEPLTIAAAKTPKFRAGKALKDAL"
     gene            complement(23878..26328)
                     /gene="lon"
                     /locus_tag="ACFOAE_000209"
     CDS             complement(23878..26328)
                     /gene="lon"
                     /locus_tag="ACFOAE_000209"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HFC6883782.1"
                     /translation="MTQKEKHFEEYAALATLPLRDVVVYPHMVLPLFVGRPKSIAALE
                     NAITREEPVFLLAQTDAALEEPVAADLYQTGTVAQVLQVLKLPDGTVKVLVEGLYRGR
                     VLTIEDTGGLFVSHIETVVEEDTGGNTDLEAVRRTLLAQFEQYAKLNKKIPAEIIGSI
                     NGIAENSRLTDTVAAHLQLKLAQRQQILEIPEIGKRMEFLLAQLESELDIMQAEKRIR
                     GRVKRQMEKSQREYYLNEQIKAIHKELGEEDENGELDALEAGIKKAGMSKEAEEKCLS
                     ELKKLKMMPPMSAESTVVRNYIDTLLELPWKKKSRVSKDIAKAGLVLDTDHYGLEKVK
                     ERILEYLAVQKRMDKLKGPILCLVGPPGVGKTSLGESIAKATGRKYVRMALGGVRDES
                     EIRGHRRTYIGSMPGKILQNMAKAGVKNPLFLLDEIDKLGSDFRGDPASALLEVLDPE
                     QNNKFADHYAEVDYDLSDVMFIATSNSLNIPTPLLDRMEIIRLSGYTEDEKINIAMQY
                     LVPKQMKRNGVKEGELAIEESAVRDIIRYYTREAGVRSLDREIAKICRKVVMQITLDE
                     DSKTKKTGKAKPRAVKVNEKNLHDYLGVRRFDYGVAESENRIGQVTGLAWTEVGGELL
                     TVEAAALPGKGVIQCTGQLGDVMKESVSAAWSVVRSRAESVGLAPDFYEKKDIHVHVP
                     EGATPKDGPSAGIAMTLAMVSAFTKIPVRADVAMTGEITLRGEVLPIGGLKEKLLAAL
                     RGGIKHVLIPKDNLKDLEEIPENVKTGLTIHPVKWIDEVLALGLESQPEPWAEPSGAE
                     AAAESASKPKPRSRATKH"
     gene            26428..26604
                     /locus_tag="ACFOAE_000210"
     CDS             26428..26604
                     /locus_tag="ACFOAE_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide synthase"
                     /protein_id="HFC6883783.1"
                     /translation="MPSETFRLQTAWAWKDKAGTKNCSVLPLLAVPSVWFAVLPPYFQ
                     NMTQVFHVFFYFSR"
     gene            26579..27682
                     /locus_tag="ACFOAE_000211"
     CDS             26579..27682
                     /locus_tag="ACFOAE_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HFC6883784.1"
                     /translation="MSSFIFPDNGFEWRNESLQKPPKGWHYVRESGANGILKAAYQNI
                     ATVWQGDFHNAKQVLSAMKKKVRKPAAVRSDADIAALFHAHRMKQAQQSRILNMLAVE
                     IRPGFVLDNKRAPDIRAALLDVYGEADGKPFFLPLNLLLGFMGAHEWHKKGVAVPQLG
                     GSIHVPFGVFSPLRGEYLDLLAHAPSTGFQTAFDIGTGSGVLAAILAKQGIPSVIGTD
                     TNPKAVACARANIARLGFEKQVEIRETDLFPEGFADLIVCNPPWLPAKPTSAVESALY
                     DPESAMLAAFLRDAPKHLNPDGEIRLIISDLAEHLGLRPADFLEKAFIRAGLRVADMM
                     KTKPKHKKAANPSDPLAFARTRETTFLYRLKKA"
     gene            complement(27710..29455)
                     /gene="recD"
                     /locus_tag="ACFOAE_000212"
     CDS             complement(27710..29455)
                     /gene="recD"
                     /locus_tag="ACFOAE_000212"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HFC6883785.1"
                     /translation="MERQTDEFAQAAARAAIWFLARYAGSSDEVLANCTERLFQALQN
                     GHSFIRLSGGEADALSALAPVVGTSAAPLILEGRRLFLGRMWQLEYDLAAEIKRLAAA
                     DTSAPDAAGARQNLAKWFQGTGSEGQRDAAALALLQSFMVITGGPGTGKTTTVAKLLA
                     LICGEDENLPNIALAAPTGKAAAHMARALHRAINGFDAPEAVRRHLLKLEGQTVHRLL
                     KLRPPKMQAAFNPVYPLPFDVLVIDEASMLDTVLMLQLLKAVKTGARVILLGDENQLP
                     SVGIGDVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPLLAQNTAHLSFSHRFGD
                     NSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGN
                     IEAAYAGISDIVVLAAWRQDAEDFNEAYCSHVRRKMNIPEHQAYFAGEPIMIRQNDYA
                     LELFNGDIGLIMEDVGRQGSLAAYFADADGFKKVAVSCLPDFEPAFAMTVHKSQGSEY
                     REVWLLPPSAAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGEETFRQAAATVKTR
                     QTALGSMLERVFSQE"
     gene            complement(29523..30218)
                     /gene="lolD"
                     /locus_tag="ACFOAE_000213"
     CDS             complement(29523..30218)
                     /gene="lolD"
                     /locus_tag="ACFOAE_000213"
                     /EC_number="7.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HFC6883786.1"
                     /translation="MSELILKCEGVGKRYRDGGLDVLVLHGLDLEIRAGESTGIIGSS
                     GSGKSTLLHILGGLDMPSEGRVLLMGEDLRTLNQRRLGDLRNRHLGFVYQFHHLLPEF
                     SALENVMMPLLIGKKSREEAAEAAMAMLEKVGLKHRSTHRAGELSGGERQRAAIARAL
                     VTQPKCLLADEPTGNLDRANARNVLDMMLELKTELGTGLVVVTHDDELAGRFGRVMVM
                     KDGSLHPKQGANA"
     gene            complement(30211..31458)
                     /locus_tag="ACFOAE_000214"
     CDS             complement(30211..31458)
                     /locus_tag="ACFOAE_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit"
                     /protein_id="HFC6883787.1"
                     /translation="MFSLEAWIGLRYLRAKKRNGFMSFITMVSIAGIALGVTALIVVL
                     SVMNGFQKEIRGQLLNVAPHAEIGYIDNTDTDWRNLLRFTENRKGILAAAPYVSNQAL
                     LANAGEIRGVQMRGILPSEERKVVEYGDKMPAGKFEDLIPGEFDIILGVGLAEALGAE
                     VGNKVTVITPEGNVTPAGVVPRLKQFTVVGLVKTGVYEVDNSLAMTHIQDARVLYRLD
                     KEVAGLRLKLADPQNAPALTAKLIPEAQRDTVWVRDWTFSNRSYFEAVELEKRMMFII
                     LTLIIAVAAFNLVSSLVMAVTEKQADIAILRTLGLSPGGVMKIFMVQGAFSGFFGTLA
                     GVVCGVLLGWNVGRVVAFFENLLGVHLINSQVYFIDYLPSDVDMGDVALIACISLGLS
                     FVATLYPSRRASKTQPAEALRYE"
     gene            31663..31941
                     /locus_tag="ACFOAE_000215"
     CDS             31663..31941
                     /locus_tag="ACFOAE_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883788.1"
                     /translation="MNIRTAFALCAIALSAAAAAYAKEIKIDANNTPYSEADAQKLAA
                     TAVGMGVKEPISLNGGSGSITVSGSSATQCVFKVGNGGALQIKGLNCK"
     gene            complement(31997..32614)
                     /gene="recR"
                     /locus_tag="ACFOAE_000216"
     CDS             complement(31997..32614)
                     /gene="recR"
                     /locus_tag="ACFOAE_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFC6883789.1"
                     /translation="MSHKKQDAFQGLIDALKVLPNVGPKSAQRIAYHLLQHKRKEAEK
                     LVDALQTALKQVYHCAMCNTFCEGGLCDICADETRDGRRLMVVHMPADVSNMEAANCH
                     DGLYFVLMGQINTALGMDVSAIALDRLAQRLGGGEVEEIIIATAFTAEGNATAYVLSE
                     FFKNLPYKVSRLSQGIPLGGELEYVDAGTLAQAVYERRLIKEGGA"
     gene            complement(32681..34219)
                     /locus_tag="ACFOAE_000217"
     CDS             complement(32681..34219)
                     /locus_tag="ACFOAE_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SurA N-terminal domain-containing protein"
                     /protein_id="HFC6883790.1"
                     /translation="MFHSIEKYRTPAQVLLGLIALTFVGFGVSTVSHPGADYIVQVGD
                     EKISDHSINNAIQNEQADGGGPSRDAVFQSLLQRAYLKQGAKLMGISVSSEQIKQIIV
                     DDPNFHDANGKFDHALLNRYLSQRHMSEDQFVEEIRDQFALQNLVNLVQNGVLVGDAQ
                     AEQLIRLTQVNRTIRSHTFNPDEFIAQVKVSEADLQKFYNANKKDYLLPKAVKLEYVA
                     LNLKDFADKQTVSETEVKNAFEERVARLPANEAKPSFEQEKAAVENELKMKKAVTDFN
                     KAKEKLGDDAFNHPSSLAEAAKNSGLKVETQETWLSRQDAQMSGMPENLINAVFSDDV
                     LKKKHNSEVLTINSETAWVVRAKEVREEKTLPFAEAKDAVRQAYIRAEAAKLAENKAK
                     DVLTQLNGGKAVDVKWSEVSVLGAQQARQSMPPEAYAELLKAKPANGKPAYVRLIGLP
                     APVIVEVQAVTPPDDIAAQLPLAKQALAQQQSANTFDLLIRYFNGKIKQTKGAQSVDN
                     GDGQ"
     gene            complement(34279..34653)
                     /locus_tag="ACFOAE_000218"
     CDS             complement(34279..34653)
                     /locus_tag="ACFOAE_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HFC6883791.1"
                     /translation="MIILHGIPNCDTVKKAKNRLAGYGLEFEFRDFKKQVPSEAEICS
                     WLEQVPLATLLNKRGTSWRKLDAETQQKALFSTAEAVKLMSEMPSLIKRPVLECGGKV
                     YAGFSEETYDGIFNRQAPCRQG"
     gene            34803..36431
                     /locus_tag="ACFOAE_000219"
     CDS             34803..36431
                     /locus_tag="ACFOAE_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HFC6883792.1"
                     /translation="MISTNGITMQFGAKPLFENVSVKFGEGNRYGLIGANGSGKSTFM
                     KILGGDLEQTAGEVAIENGVRLGKLRQDQFAYEDMRVLDVVMMGHTEMWAAMTERDAI
                     YANPEATEDDYMKAAELEAKFAEYDGYTAEARAAELLSGVGISEDLHNATMAEVAPGF
                     KLRVLLAQALFSKPDVLLLDEPTNNLDINTIRWLEGVLNQYDSTMIIISHDRHFLNEV
                     CTHMADLDYNTITIYPGNYDDYMLASAQSRERALKDNAKAKEKLQELQEFVARFSANK
                     SKARQATSRLKQADKIKSEMVEVKPSTRQNPYIRFEADEKAKLHRQAVEVEKLAKRFE
                     TQLFKNLNFILEAGQRLAIIGPNGAGKSTLLKLLAGAYNPEYSDGLLPDEGSIKWAEK
                     ASVGYYPQDHENDFDVDMDLSEWMRQWGQDGDDEQVIRGTLGRLLFGSNDVVKKVKVL
                     SGGEKGRMLYGKLLLLKPNVLVMDEPTNHMDMESIESLNMALEKYNGTLIFVSHDRQF
                     VSSLATQIIELDGKGGYEHYLGDYESYLEKKGVA"
     gene            36503..37756
                     /locus_tag="ACFOAE_000220"
     CDS             36503..37756
                     /locus_tag="ACFOAE_000220"
                     /EC_number="2.7.7.72"
                     /EC_number="3.1.3.-"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004810 - CCA tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional CCA addition/repair protein"
                     /protein_id="HFC6883793.1"
                     /translation="MQTYLVGGAVRDYLLGLPVKDRDWVVVGADAQTMLAQGFQPVGK
                     DFPVFLHPETHEEYALARTERKTAKGYVGFSFHADKDVTLEQDLMRRDLTINAMAQDA
                     DGKIIDPFGGQRDLAAGILRHVSPAFAEDPVRILRTARFAARYRFEIAEETIKLMRQM
                     VENGEADALVAERVWQELAKGLMEKNPRKMIEVLRECGALKVLLPEVNALFGVPQRAD
                     YHPEIDSGIHTLMTLQRAADMGLSLPERYAALLHDLGKAKTPSDILPRHHGHDLAGVE
                     PMREVNQRLRAPKHCAELAELVCRWHIIFHQVGQLKSQTILNVLKKTDAFRRPERFQT
                     ALNVCIADTQGRLNREHTPYPQRAHWLALLEAANQADSGKIAAECRAQGKAHLIAEQI
                     DRARLAQIAPLQKAFRAAQDKTEKH"
     gene            37979..38287
                     /locus_tag="ACFOAE_000221"
     CDS             37979..38287
                     /locus_tag="ACFOAE_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883794.1"
                     /translation="MTLKTDLLPKINNEDYQRLILKHSAEFSGGEIRLLNEILEKFNF
                     DVVQAQALAQAVMQQIRFDPNAYHIDSDDEDTTGICPHCINPPMPPLRDYLVWRETRG
                     "
     gene            38369..39400
                     /gene="ruvB"
                     /locus_tag="ACFOAE_000222"
     CDS             38369..39400
                     /gene="ruvB"
                     /locus_tag="ACFOAE_000222"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFC6883795.1"
                     /translation="MLQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQD
                     KAKEQLAIFIQAAKKRGEALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLER
                     AGDLAALLTNLDPHDVLFIDEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKID
                     LPPFTLIGATTRAGMLTNPLRDRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMSEEGA
                     EEIAKRSRGTPRIANRLLRRVRDFADVKNNGTIDGGIADAALSMLDVDAQGLDVMDRK
                     FLEAVLHKFGGGPVGLDNVAAAIGESTDTIEDVIEPYLIQQGFLQRTPRGRMATERAY
                     LHFGLPVEK"
     gene            complement(39423..40151)
                     /gene="rpe"
                     /locus_tag="ACFOAE_000223"
     CDS             complement(39423..40151)
                     /gene="rpe"
                     /locus_tag="ACFOAE_000223"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFC6883796.1"
                     /translation="MTTYRIAPSILSADFARLGEEVESVIAAGADLIHFDVMDNHYVP
                     NLTFGPMVCAALKPYASVPIDVHLMVEPVDDLIQSFAKAGASIITFHPEASRHIDRSL
                     SLIRDMGCQAGLVLNPATPVYLLENVLDRLDMVLLMSVNPGFGGQSFIPHTLEKIRRV
                     RAMLDRYEAQSGRHIAIEVDGGIKTDNIAAVARAGADTFVAGSAIFGKPDYKAVIDAM
                     RAELEKSGRLNLAPMIEIEMPSEN"
BASE COUNT         9104 a        10492 c        10795 g         9779 t
ORIGIN      
        1 tgagctaagg cgaggcaacg ccgtactggt ttttgttaat ccactataaa atataccgca
       61 aaacatacca caaaaaacgg taacggatag ttgtaagcgg ttgatgacga ttatagacaa
      121 taacgggttt tcccaatgaa attattgttt gaataataaa aaatcccaaa ccgtaaaagt
      181 ttgggatttg tatttggcag agaggaaggg attcgaaccc tcgatacgct attcacgtat
      241 acacgctttc caggcgtgcg acttaaacca ctcatccacc tctctaatgg cggaaattat
      301 cccaatcgga ataatttatt tggtgcccgg gagaagactc gaacttccac acccgtgagg
      361 ataccagcac ctgaagctgg cgcgtctacc aattccgcca cccgggcaat ctaaatattg
      421 aaataaagca aagcatttga tttggtgccc gggagaagac tcgaacttcc acacccgtga
      481 ggatactagc acctgaagct agcgcgtcta ccaattccgc cacccgggct ttgctttatt
      541 tgctgttttg cggtacagtg tcctgccgca aagaagtcgc tattatatag ttcataaaga
      601 gaatgtcaac agtccaaatg aataaaaata ttaaatcttt aaatttacgg gaaaaagacc
      661 cgtttttaag tcgtgaaaaa cagcgttatg aacatccttt gcccagtcgg gaatggataa
      721 tcgaattgtt ggagcgcaaa ggtgtgcctt caaaaatcga atcgcttgcg cgcgagctgt
      781 cgattacgga agacgagtat gtctttttcg aacgccgtct gaaggcgatg gcgcgggacg
      841 gtcaggtttt aatcaaccgc cggggcgcgg tttgcgcggc ggacaaattg gatttggtca
      901 aatgccgtgt cgaggcgcac aaagacggtt tcggttttgc cgtgccgctc acgcccgcca
      961 aagacggtga ttttgttttg tatgaacgcc agatgcgcgg cattatgcac ggcgatattg
     1021 tcactgttcg tcctgccggc atggaccgta ggggccgccg cgaagggaca gttctggata
     1081 ttgtcgaacg cgcgcaaagc aaagtggtcg gccgtttcta tatggatagg ggcgtggcga
     1141 ttttggagcc ggaagacaag cgtctgaacc aaagcatcgt attggaaccg gacggcgtgg
     1201 cgcgtttcaa acctgaatcc ggtcaggtca tcgtcggcga aattgaggtt tatcctgagc
     1261 aaaaccggcc ggcagtggca aaaatcatcg aagttttggg cgattatgcc gacagcggca
     1321 tggagattga aattgccgtg cgcaagcatc atttgccgca ccaattcagt gaagcgtgtg
     1381 ccaaagccgt gaaaaaaatt cccgaccatg tacgcaaaag cgatttgaaa ggccgcgtcg
     1441 atttgcgcga cctgcctttg gtaacgattg acggcgaaac ggctcgagat tttgacgatg
     1501 cggtgtttgc cgaaaaaatc ggacgcaatt accgtctggt cgtggcgatt gccgatgtca
     1561 gccattatgt ccgccccgat gacgctatcg acacggacgc tcaggaacgc agcaccagtg
     1621 tttacttccc gcgccgcgtg attcccatgt tgccggaaaa cctgtccaac ggcatctgct
     1681 cgctcaatcc taatgtcgag cgtttgtgta tggtgtgcga tatggttatc acttacgcgg
     1741 gcaatattaa agaataccgc ttctaccccg ccgtgatgcg ctctcatgcc cgcctgacct
     1801 acaaccaagt ttggaaatgg ctttcaggcg gcatcgggca tccgttcaaa gcccaaatcg
     1861 acacgcttta caaactcttc aaaatccttc agaaaaagcg tttcgaacgc ggggcggtgg
     1921 agtttgacag catcgaaacc caaatgcttt tcgacgacaa cggtaaaatt gaaaaaatcg
     1981 tccccgttgt ccgcaacgat gcccacaagc tgattgaaga atgtatgttg gcggcaaacg
     2041 tttgcgcagc ggattttctg ttgaaaaaca agcataccgc attgttccgc aaccatttgg
     2101 ggcccacgcc cgaaaaactc gccgccttgc gcgagcagtt cggtctgttg gggcttcaac
     2161 ttggcggcgg cgacaacccg tcgccgaaag actatgccgc gcttgccgga cagttcaaag
     2221 gcaggccgga tgccgaattg ctgcaagtca tgatgttgcg ctccatgcaa caggcggttt
     2281 acgaaccgca ttgcgacgga cactttggtc ttgcctacga agcatacgcc cacttcacct
     2341 cgcccatccg ccgctatccc gacctgaccg tacaccgcgc catcaaagcc gtgttgaatc
     2401 agcaaaccta cacgccaaaa aaaagctggc aggctttggg cgtgcatacc tcgttctgtg
     2461 agcgccgtgc cgacgacgcc agccgcgacg tggaaaactg gctgaaaacc tactatatgc
     2521 gtgacaaagt cggcgaaata tttgaaggca aaatttccgg ggtggcaaat tttggaatat
     2581 ttgtcacttt ggacgatatc catatcgacg gtctggtgca tatcagcgat ttgggcgaag
     2641 actatttcaa cttccgcccc gaaatcatgg caatcgaagg tgaacgcagt ggcatccgtt
     2701 tcaatatggg cgacagggtt gccattaaag tggcccgtgc cgatttggat gatggaaaaa
     2761 tcgattttgt cctgattgcc gaggggagcg gcagagggcg gaaagttaaa tcatccgcgt
     2821 ctgccaaacc ggcagggacg gcggggaaag ggaagccgaa aaccgccgcc gggaaaaaaa
     2881 cagcccgagg cggcaaagta aggggaaggg gcgcgtctgc cgccgcagaa tcggggaaaa
     2941 aggcaaagaa accggttccg attaaggtaa aaaaacggaa aggcaaatca taatgctgac
     3001 ggggcggctt ggggagggag gggcatactt tcccgaagcc gccgcccgat tttttgatat
     3061 ggcggccggc gcatcatttc aggccaatcg aaacgcccgt attgaaagat tgcgtttatt
     3121 tccaccgccg ttttaaaggc cagcggtatt cggcagacgg ggcgcaaacg gcgttcagac
     3181 ggcattttca ttctttcggc gtgtccgtcc gaatggcttt gcccgtccgc gcaatcagcc
     3241 cgtgcggctt gccttgaacg gacaaaaaat gccgtctgaa acccgaaaat caggtttcag
     3301 acggcatttt gccttgaaaa ggctgttcaa atcagcggtg gtagttcggt gcttctttag
     3361 tgatttgaac gtcgtgaacg tgcgattcgc tcatacctgc ggaagtgatt tccacaaatt
     3421 cggctttttc gtgcatttcg gcaatattgg cgcaacccaa gtaacccata ctggaacgca
     3481 gaccgccggt cagctggtgg atgatgttca caatcgggcc tttgtaagga acgcggcctt
     3541 cgatgccttc ggggacgtat ttgtctgcgc tgtcggtttt gtcttggaag tagcggtcgg
     3601 cagaaccttg gctcatcgcg cccaaggaac ccataccgcg ataggatttg tacgagcggc
     3661 cttggtagag ttcgatttcg cccggcgctt cttccgtgcc tgcaaacata ccgccgagca
     3721 tgacgctgta cgcgcctgcg gcgagggctt tggcgatgtc gccggagaag cggatgccgc
     3781 cgtcggcaat cagcggaacg cccgtgcctt tgagggcttc ggcaacgttg tgaatggcgg
     3841 tcagttgcgg cacgccgaca cctgccacga tacgggtggt gcaaatcgat cccggaccga
     3901 taccgacttt gacggcatcc gcgccggcgg cgaccaaatc caatgcggct ttggcagtgg
     3961 cgatgttgcc gccgatgact tggatgtgtg gataggtttc tttcacccat ttcacgcggt
     4021 caatcacgcc ttggctgtgc ccgtgggcag tatcgacgac aatcacgtcc acgccggctt
     4081 cgaccaaggc tttgacgcgc tcttcggtat cgccgccggt gccgactgcc gcaccgacgc
     4141 gcagacggcc ctcggagtct ttgttggcgt tgggaaactc ggtggttttt aaaatatctt
     4201 taacggtaat cagacctttg agttcgtctt tttcgttcag aaccaaaacg cgctcgactt
     4261 tgtgcgtgtg catcagttcg cgcgcttcgt ctatgcttgt gccttcgggg acggtaacca
     4321 gacgttcgcg cggggtcata atggcggaaa cgggcaaatc gacgcggttt tcaaaacgca
     4381 ggtcgcggtt ggttacgatg ccgacgactt tgccgttttc aacgacgggc aggccggaca
     4441 ttttgcgttt gcgctgcgca cgcatttcca agacttcgcg gatgagcgtc gtcggtgcaa
     4501 cggttacggg gtctttgacc acgccgcttt cgtggcgttt cactttggaa acggcgcgcg
     4561 cctgcatttc gggcggcatg tttttatgga tgatgccgat gccgccttcc tgtgccatcg
     4621 aaatggcgag gcgcgcctcg gtaacagtgt ccatcgcagc ggaaagcagg gggaggttga
     4681 gtgtgatttc gcgggtgagc ttggtttgaa gtttaacgtc tcgcggcagc acggtcgaat
     4741 gtgcgggaac caacaaaaca tcgtcgaaag tataggcttt ttctacgata cgcataatgc
     4801 tcggtctttc agtttgtgca agatgcacgg cattatagca cgttaccggc ggcttgacag
     4861 tttatattgt ttgcaatatc ccccgccttc aggcggcata cggcgcggcg gcggaatgcc
     4921 gtctgaaaac cggcagggtg cttatgccaa ctgttccagc aaagcctgtt tcaatgagga
     4981 ctggattttt gggtttttca ggtcggggct aaaaacggta aaactgtctt cggcgcgttc
     5041 atccagtgtg gagattttgg catagcgcag gctgacgttg tgggcgaaaa agacttccgc
     5101 catatcggcg agcaggaagg ggcggttgac ggcggtgatt tcgacggagt accaatcggg
     5161 gtagtcttct tcgggggtaa tggtgatgct tggcgcgatc ggcatatagc ggctgcggcg
     5221 gctgatgcgg cggctatggc tggagatttc ggcaacggtg tgtccgtgga taaagttgtt
     5281 gagttcggct tcgagcgcgc tttggatgtc ggggtagtct tcgggagcgt gctgcgaggg
     5341 gatttgcacg atgaaggtgt cgaggatgta gtcgtgttcg gtgataaagg cgcgggcggc
     5401 gaggatatcg aagccgtggc ggctgaaaat gcggcagagg cgggcgaaca ggcgcgggcc
     5461 gttgggcata aaaaccatga cttgaaagct gtcgcttttg ggcaggatgc ggctgcggac
     5521 gatgggggtt tcaaagtcgt ggactaggtt ggcggcgtgc cacaggattt cgcgggactg
     5581 gtggcgggcg aagtaggcgg aaccgagcgc gttccatagt tttttctgct gtttttcggg
     5641 gacggcggcg cgggtgagta agtcggcggc ttcctgccgg cggcggccga agagggtgtg
     5701 cgggttgccg ccgttgcctg taaggtagcg tccggcggca tggaagaggc tttccagcag
     5761 gctggcgcgc catgcgttcc acagcttggg attggtgccg cgtatgtcgg aaatggtcag
     5821 aaagtagagc gcgctgaggc gttcgtgggt ttggacgcgt ttgcagaagg catcgagtac
     5881 gctggggtct tggatgtctt ctttttgggc gacggtggac ataagaagat ggttttcaac
     5941 cagccaggcg agcaggtcgc tttcttcttc ggtcaggaag tggtcggcgg caaattggcg
     6001 cgcgtctgcg atgccttgta tggcatggtc gccgccgcgt cctttggcga tgtcatggaa
     6061 aaaggcggca aggtagagga tgtcttgttt ttcaaaggac tgcatcagtg cagaggcgta
     6121 gggcagctcg tggctgtgca tatccaaggc aaggcggcgg acgttgcgga cgacggtgag
     6181 gatgtggtcg tccacgggat agatgtggaa caggtcgtgc tggagcaggc cgacgatttt
     6241 ttcccacgcg ggcaggtagc gtcccaatac gccgtagagg ttgaggaagc gcagggtttg
     6301 ggtcagtccg ttgccgttgc ggaaaaagcc ggcgaagcgg tggcgatttt cagaattttg
     6361 gtagaagctg cggttgattt tgcgcgtcgc gccccaccat gcgcgcaggg tttgcggttc
     6421 gagcgcggta atatcgttgc gctgctgcat gatttcgacg attttgaaaa tgtgttcggg
     6481 ccgtctgaaa aaaatatcgg tgtgccgcgc ggcgatttgg ttgttgactt ggatgtagtc
     6541 gtcgtcaatc cgcagggtaa cgcgcaacgg ggtggaggaa acgcggcttt gcagcatagg
     6601 cgtgaggatg ccgcccagtt gtttgacggt tttaatcgcg cggtaaaaca cgcgcatcag
     6661 ttcttcgctt tggcggcgga ggttcaagcc ttcataaccc atgctttcgg cgacttgcgg
     6721 ctgcaaatcg aacagcaggc ggtcttcggc gcgattggcg tttaaatgca gatggatgcg
     6781 gatgtgggcg aggcggcggt agccgtgcga aagcataccg gcttcggcac gcgtcaaaat
     6841 ccgctgtttg agcaggtcgg gcaggttggt cgccaagcct tgtgctttcg ctatccaaag
     6901 cagggtgtgg atgtcgcgca gaccgcccgg acagcttttg atgtttggtt ccaataccgc
     6961 ccctgagcct tgcgatttgg cgtggcggtg ttccatctcc accagttttg cctcgacaaa
     7021 cgccggcaca ttgcgctgcg cgttcatttt tttcgccagt tcgtccgccg tttggcggtt
     7081 gccaaacaaa aacctagcct ctaaaaacgc tgtgtccccc gtaatatcat tgcgcacgct
     7141 ttcacatagt tcatcaacgc tgccgctttt tacagacggc atcagtttgc agtcccacag
     7201 ggtttggaca aaccgggcaa tctgttcctg aatgccgtct gaaagcgggg caggggagac
     7261 aaccgccaaa tccacgtccg aacagggata cagttcgccg cgcccgaagc cgcctaccgc
     7321 catcaggcat aacgcgctgt tttgaaaata ctctgcccac aatgccgcca gtaaggtttc
     7381 gactgccgcc gtgtattctc tgaaaaatac cgacacgcgg ttggctttca aataatgcgc
     7441 ttcggcggca tcgcgctgct gtttgaaggt ttccagtgct gaagacaggt ttgcaggcat
     7501 ttttattctt tcgattggcg ggaaaaaggg aggcggatgg ttcggcggtc aaataccgct
     7561 ttcagacggc atttgtcggg tatcggcgga attggtcatc agcttcaacc gttcctgcgg
     7621 cggcagcagc aactgatacg ccgccacgcc caaagccgcc gccatttttt cgatattcga
     7681 cagggcgatg ttccagcgtt tgcgctcgac tgccgacaca taagtcctgt ccaaaccgca
     7741 ttgccgcgcc aattcttctt gcgaccaacc cttgttcacg cggaaaagcc gcatattgta
     7801 tgccaatacc gcccgcaaat cctgttcgtc aggcagttcg gcaggcagag tcaatttgtt
     7861 gcccatcatt tgcttccaaa taaatggtta aagttaagca tttgctgtta cggattttac
     7921 ttcacataaa agccaaaaaa aaggggtggc ggcagccaca cccaaacaca cacacatcaa
     7981 gaggaaagag gtaacatcaa gacagattgg gaaacagcaa acaagcaatc tagatttcat
     8041 atcggtatta tcaaacaaaa accgttatcg agtattgatt caaatcaatt gagatttgat
     8101 tcgcaaaccg gtaaagaaaa acggcatacc cgtttatacg gatatgccgt ctgatgatgc
     8161 aggggactgc tgtatttggc agtggtttgt gttttagtcc tcttgcgccg ctgtttgcag
     8221 gtagttcggc aaaccaattt tgccgattag ttcctgctgg gtttcgagcc agtcgatgtg
     8281 ttcttcgttg gtgtcttttt gtttttccaa caaatcacgg ctgacataat cctgttgcgc
     8341 ttctgccacg gaaattgccg caatcaatgc ctcatgtttt tctttctctt tttccaaatc
     8401 gcaggcgatg atttcttcgg tggactcgcc aatcagaagc ttgcccagtt cttgcaggtt
     8461 cggcagacct tcgaggaaca gaatgcgctc gatcaaatcg tcggcagctt tcatttcaac
     8521 gatggactgt ttgaagaaat gttcgcccag ttcttcaaag ccccagtttt tcaaaatacg
     8581 ggcgtgaagg aaatattggt tgatggttac cagcagcaag cctaagtttt tgtttagctc
     8641 gcggataacc agacggtcgc ctttcatacg gactcctttt attccgaata cggattacag
     8701 ttggctttgg tagtagttgc cttcgccaat taactcgatc aggcgaagct gctgttccag
     8761 ccagtgggcg tggtcttctt cggtatcttt cagttgggca accatcaggt cgcgcgtaac
     8821 atagtcttga gcctcttcgc acagtttgat gccttttttc aacgcatcac gtacttcata
     8881 ttcggtttgc aggtcggctt tgaggcagga aaccacgtcc gtgccgatat tcagttcggc
     8941 gcgtgccatt ttcggcgtgc cgcccagcat caggatgcgg cggatgaagt cttcggcgtg
     9001 tgtggtttct tcttccatct cgtgattgag acgttcaaaa agtttggtgt agccccattc
     9061 ggagtagagg cgggagtgga taaagtattg gtcgcgtgcc gccagctcgc cagacagcaa
     9121 ttcgttcata taatcaacaa cagcttgatt gccttgcata atatctctct ttctgtaact
     9181 tggttttcgg tatgtctgaa cagcatctgt gtcgctattc gggatgcgtg cattgtatgc
     9241 aaaagctgtc ggcatgacaa attttctatt taaaatacaa acaattatca aaagaaatag
     9301 ggcgtattcc ccgatgcctt ccaaatcagt atgctgtttc ttatcggttt ttttgctgct
     9361 aaaactaaga atccatctca tccataaaga acatttacac ttattaacca tagcgaaaag
     9421 caaatactgt acggtttttt atcaaaattt ataatgaatc gttctcatta accgacagat
     9481 tcttttgaga ttatcggatt ttgggaataa attatgccgt ctgaggggct ttcagacggc
     9541 atagataatt aaagctgatt aaacaacgcg gcagacagca gcgtaggaaa ttatttttta
     9601 cttcggaacg gtattttggg tttaatgatg cccgcaaccg ccgtggcttt ccctcaaggc
     9661 ttccgccgcc tgttcgtcgg cgtggtagct ggaacgcacc atcgcgccga tggcggcatt
     9721 gctgaagccc agttcgtatg cttctttttc aaagattttg aactgctcgg gcgtaacgta
     9781 gcgcaagacg ggcaggtggc cgtctgaagg ttggaggtat tgtccgatgg taatcatctc
     9841 gatattgtgc gcccgcatat cgcgcataat ttcgcgcacg tcttcgtctg tttcgcccaa
     9901 gccgaccata atgccggatt ttgtgggaat atgcggcatc atttctttat aacgttttaa
     9961 taagtctaaa gaatgttgat aattggcgcc ggggcgggct tttttgtaca ggctgggatg
    10021 ggtttctagg ttgtggttca tcacgtcggg cggggtttcg gcaaggattt tgagcgcgat
    10081 gtccaagcgg cctcggaagt cggggacgag gatttcgatt ttggtattcg ggctggtttc
    10141 gcggatggct ttgatgcagt cggcgaaatg ctgtgcgccg ccgtcgcgca ggtcgtctcg
    10201 gtcgacggag gtgatgacga cgtaacgcag gttcatggct ttgacggatt cggcgaggtt
    10261 tctcggttcg tcggggtcga gcatattggg ccgaccgtgt cccacgtcgc agaacgggca
    10321 gcggcgggtg cagatgtcgc ccataatcat gaaggtcgcc gtgcctttgc tgaagcattc
    10381 gccgatgttg gggcaggagg cttcctcgca aacggtgtgc attttttgtt cgcgcaaaat
    10441 gtctttgatt tcaaagaatt tgcgcgatgg aagtttggcg cgtatccatt cgggcttttt
    10501 taatttttcc tgaaggggga cgactttgat ggggatgcgg gcggttttgt ccgcgcctct
    10561 gagtttgatg ccgcgtttgg ggtcgtcggt tttgatttca ctcattgttg tctgctttcg
    10621 gtgtgaattg tgtttcaagg tgtgcggtaa gtttggcggc gacttcgtcc ggcgtggggc
    10681 agggttggac aaaatccgcg atttgcgtca tttccatacc ggcgtagccg caggggttga
    10741 tgtgggtaaa cgggcttaaa tccatattga cgttgagcgc aagcccgtga tagacggagc
    10801 cgtttttgat acgcagcccc agtgaggcga ttttgcgttc tccgacataa acgccggggc
    10861 gtttggggtc tgccgccgct tcgatgccgt attctgccaa tgtggcgatg atgctgtttt
    10921 caagcgcgga cacgatgttt ctaacactgg ttttgcgccg tttgaaatca atcatcgtat
    10981 aaacgaccaa ttgcccgggc ccgtgatagg taatctgccc gccccggtcg atttggacga
    11041 cgggaatgtc gtcgcgaatc agcaggtgtt cgggttttcc cgccagtcct tgtgtgaaca
    11101 cgggcgggtg ttcgacgacc cacagttcgt cttcggtgtc ggcattccgt ccggcattaa
    11161 aggttttcat cgcttcaaaa gtcggcagat attcgaccaa acctttgtgt atgattttca
    11221 tctcaaagta ccactttgac cagttcgtgc gaagtcagcg cacggtagat gttgtccaat
    11281 tgttcttggt tttcaacctt tacctgtacg gtggcaccgg tatagttgcc tttgctgctc
    11341 ggacgcgtgg tgatgtggtg cgcctgcgtg tcgggggcgt ggaggcggac ggtgtctaaa
    11401 accgcctgct cgaactcggg atgcaccgcg cccattactt tcaatgggaa ggtgcaggga
    11461 aattcgatga gggatgtttt gtttttttgt tcggtcatga tgtgctgcct tgtcgtgtac
    11521 ggtatgccgt ctgaaggcgg gtttgccttt cagacggcat cggatgtgcg ttattttagc
    11581 ctaaaccgcg ataacaggct atcgggaagg cggaggcttt tttgacggcg cggcggttct
    11641 gctatactgg cgcacaatat tatttttaga agggtggttt ttatgtatcg gaggaaaggg
    11701 cggggcatca agccgtggat gggtgccggt gcggcgtttg ccgccttggt ctggctggtt
    11761 ttcgcgctcg gcgatacttt gactccgttt gcggttgcgg cggtgctggc gtatgtattg
    11821 gaccctttgg tcgaatggtt gcagaaaaag ggtttgaacc gtgcatccgc ttcgatgtct
    11881 gtgatggtgt tttccttgat tttgttgttt gcattattgt tgattattgt ccctatgctg
    11941 gtcgggcagt tcaacaattt ggcatcgcgc ctgccccaat taatcggttt tatgcagaac
    12001 acgctgctgc cgtggttgaa aaatacaatc ggcggatatg tggaaatcga tcaggcatct
    12061 attattgcgt ggcttcaggc gcatacgggc gagttgagca acgcgcttaa ggcgtggttt
    12121 cccgttttga tgaggcaggg cggcaatatt gtcagcagta tcggcaacct gctgctgctt
    12181 cccctgctgc tttactattt cctgttggat tggcagcggt ggtcgtgcgg cattgccaaa
    12241 ctggttccga ggcgttttgc cggtgcttat acgcgcatta caggcaattt gaacgaggta
    12301 ttgggcgaat ttttgcgcgg gcagcttctg gtgatgctga ttatgggttt ggtttacggc
    12361 ttggggttgg tgctggtcgg gctggattcg gggtttgcaa tcggtatggt tgcaggcatt
    12421 ttggtttttg ttccctattt gggtgcgttt acgggattgc tgctggcaac cgtcgccgcc
    12481 ttgctccagt tcggctcgtg gaacggcatc ctatcggttt gggcggtttt tgccgtagga
    12541 cagtttctcg aaagtttttt cattacgccg aaaatcgtgg gagaccgtat cgggctgtcg
    12601 ccgttttggg ttatcttttc gctgatggcg ttcgggcagc tgatgggctt tgtcggaatg
    12661 ttggcaggat tgcctttggc cgccgtaacc ttggtcttgc ttcgcgaggg cgtgcagaaa
    12721 tattttgccg gcagttttta ccggggcagg taggcggttc cgaaacatat ttgaagcgga
    12781 atacaaccct gcccgagttt aaataaaaat gccgtctgaa ccccgaaaac agagcttcag
    12841 acggcatttc atcacggctt atttggcggt tttgctgctg tcgataattt tcataccggc
    12901 agaaatcagg ctgccgatgt cggcaacatt ggcgggcata atcagcgtat tgctttcttt
    12961 ggcaagattg ttgaacgcgg cgacgtattg ttccgcaatc ttcaggttga ccgcatccgc
    13021 accgccttgg gtttgaaggg cggcggcaat ttgacggatg gcttcggcat tggcttcggc
    13081 aacaaggcgc aaggattccg cttcaccttt ggcgcggttg atgcgggcga ttttctcggc
    13141 atttgacgca ttgaccgcag cctgagcctc gccttcggat tgttggattt cggcttcgcg
    13201 ctgaccgctg gcaaggttga tttgttcgat tttacggcct tcggattcgg cgatacgggc
    13261 gcgtttttcg cgttcggcgg taatttgcgc ctgcattgag cgaaggattt cttgaggcgg
    13321 caccaagtct ttaatctcat aacgcaaaac cttcacaccc caagccccgg ccgcctcgtc
    13381 caaagccgca acaacagtac tgttgatttc gtcgcgttct tcaaacgttt tgtccaactc
    13441 catacgcccg ataacggaac gcagcgtcgt ttgggcaagc tgggtaattg ccatgatgta
    13501 gttgctcgaa ccgtatgagg cgagtttggg gtcggttact tggaaataga tgatgccgtc
    13561 aacagtcagc tgcgtattgt cgcgcgtgat gcagacctgg ctgggtacgt ctaaagggat
    13621 ttctttcagc gaatggcggt aggcaacgcg gtcgataaag ggaatcaaaa tattcaaacc
    13681 ggccgtcagg gcgcgatgga aacgcccgag cctttcgaca acgtggactt cctgttgtgg
    13741 gatgacaaca aaggatttga aaccgaaaac ggcaacggct gccaacaaga taatgaaaaa
    13801 ttccataatt cctccgagtg ttaaggtttt gcgatgataa gaaggttgcc ttccttgcgg
    13861 acgattaggg cgcgcgttcc tggttcaagc tcttcttgcc ccgtattttg cgcctgccag
    13921 tgcgtaccgc gataaaaaac ttcgtaacgg ttgccgcctg tgtgtcggag gatttcgaca
    13981 tattgtccgg catccaaatc ctgatatgaa tccgtttcaa cttttctaac ggcggttttg
    14041 gcgtgtacga accaaatacc cagcgcggaa agcagagcgg cggtcaagac ggcggcaggc
    14101 gtgctgccgg tcagcccgta agcaatgccc gaacccgcca aagccgcgct gacaaccaaa
    14161 agataaaccg ttcccgtcaa taattcgatg attaagacgg caacagcggc aacaaaccat
    14221 acagtcatac atttccccac aaagcgcgtc gtttgacaaa ataacgcaat atcagcagta
    14281 tagccgaatt tgaaaggata gggcagatat ggacacttgg cacgatgcac tcggcggcga
    14341 aaaacagcag ccgtattttc aggaaatttt aaatgcagtc aggcaggaac gtttgtcggg
    14401 acaaatcatc tatccgccgg cggcggatgt gttcaacgca ttccgcctga cagcgttcga
    14461 ccgggtcaaa gccgtcattc tcggacaaga tccgtatcac ggggcagggc aggcgcacgg
    14521 tttggcattt tccgtccggc agggtatccg cataccgccg tctttactca atatctacaa
    14581 agaattggaa accgacatcg aaggcttttc catacccgcg cacggctgcc tgacagcgtg
    14641 ggcggagcag ggcgtattac ttctgaacac ggttttgacg gtgcgtgcag gacaggcgca
    14701 ttcgcacgcc cttttaggct gggaacgctt taccgatacc gtcatcaggc agcttgcgac
    14761 acaccgcaag catcttgtct ttatgctgtg gggtgggtat gcacaacaaa aaaggaaact
    14821 gatagacagt caaaaccatt tgatattgac cgcaccgcat ccgtctcctc tgtcggcata
    14881 tcgcggtttt ttcggctgcc gccatttttc acaggcaaac agctatttga gccggcacgg
    14941 tatcgatccg ataaactgga agctgtgaat gccgatatag ccgttgccgc cggcgtgtta
    15001 aaatcgcgtt tgatttgtaa tttccattta ttaggcaaaa ccttatggca atcaaaaaaa
    15061 aatcagcttt atgcatcact ttgggcgggc tgcgacgagt tgcgcggcgg tatggatgcg
    15121 agcctttata aagaactatg tgcttacgct attgttttta aaatatgttt ctgataagca
    15181 taagtacggc ggcggcatga ttgagctgca cgccgatacg acttttgacg acatcgtcaa
    15241 actcaaaaac accgccgaca tcggcgaccg cctgaataag atcatcgccc aaattgccga
    15301 agccaacgac ttaaaaggcg tgatcgacgt tgccgacttc aacgacgaag acaaactggg
    15361 taaaggtaag gagatgatcg accgtttgag caggcttgtc ggcatttttg aaaagctcaa
    15421 cctttcttcc aaccaagccg aagacgacga tttgttaggt gatgcctacg aatacctgat
    15481 gcgccatttt gcgaccgagt caggcaaatc caaagggcag ttttacacgc ctgccgaagt
    15541 ctcgcgcatt atggcgaaga ttatcggaat cagcgcagat tgcccgtcca gcaccagcgt
    15601 ttatgacccg acctgcggct cgggttcgct gttgctcaaa gccgccgccc aagccggcag
    15661 ccaaatcagc ctttacggtc aggaaaaaga tgtggcaacc gcgtcccttg cccgtatgaa
    15721 tatgattttg cacaacaacg aaaccgccga aatcaacacc gggaacactt tgtccgattc
    15781 gtctttccgt gatgaaaacg acgggcttaa gaccttcgat tttgccgttg ccaattcgcc
    15841 ttatcccgcc cgaaaaaaac ggcgattacg cctttttgct gcatctgctc aaaagcctga
    15901 aaccaagcgg caaaggtgcg attattcttc cgcacggtgt gctgtttcgc ggcaatgccg
    15961 aagcgcgtat tcgcacggaa ttgcttaacc ttgaccttat taaaggcatt atcgggctgc
    16021 ctgccaacct gttttacggc acgggcattc ctgcctgcat catcgtcatc gacaaagaac
    16081 acgcccaaac cgcccaattt gccgaagagg gaacaaacca agttatcagt ggcggcatta
    16141 aagacggcaa caaaaaccgt ctgcgtgagc aagacattca caaaatcatc gacactttca
    16201 caaacctcgt tacagccgta tggtgcattt aagcgaaatc gcagcacaag attacaacct
    16261 taatctgcct cgctatatcg acagcggaga agttgaagac ctgcaaaatc tcgccgccta
    16321 tctttatggc ggcatacctg cgcacgatat ggacgcattg gaagcctatt ggcaagtttt
    16381 aggccgtatg aaaaacgagt tgtttgccga acacgatggc cgctttacca ctatacaacg
    16441 gaatcgattg caaatctttc ccactctcaa cagcttaaaa tcctgcggga ttggtgtgga
    16501 atttagggct aatctagtac agccccaaat ttaatccact ataaaatcga aagcagccaa
    16561 atcaaagccc atatattggc gcaccccgat tacgccgcct tcaaagccgg acacctggca
    16621 aagtttgccg cgtggcacac tcaaaacgac cttgccgcca tccaaccggg caggcttatc
    16681 cggaaatgga gcgaaagcct gctggacgcg ttcaaacccg gcagcctgat tgaagaatac
    16741 gatttctacc aaatcctgac ggactactgg gcggaaaccc tgcaagacga tgtttatctc
    16801 atcgcccaag atggctggaa ggcggttaaa aacctggccg aaatcaccaa agaaagcgat
    16861 gaagacgcga acctgaccgt cgtctttgag gaaaccgaaa ccggcaaaaa aggcaaagcc
    16921 aaaaccaagc gcatcagcaa aaaataccgc agcgaagtca tcgcccccga gctggttgcc
    16981 cgccgctact tttcagacgg catcgccaag ctggaagaaa aacaaagcga gctggaacgc
    17041 ctaagccaag aattggaaaa ccacatagaa gaacacggcg gcgaagaggg tgcgctgaac
    17101 gacgtattgg atgcaaaagg caaactttcc gccaaacttc tgaaaaccgc attggaagaa
    17161 agcggcatag aagaaggcga acgggctgtt ttacaaacca cccaaacact gatgacgcag
    17221 gaaaaagccg cgaaagacgc agtcaaaacc caaatcgaag ccctgaacct tgccgtattc
    17281 aaacaattcg gccgactttc cgaagccgaa atcaagcagc ttgccgttca agacaaatgg
    17341 cttgccgatt tacaaagccg aatcgaaaat cgcttggaaa acagtattca gcagcttatc
    17401 agccgcttga acacgctgga agaccgctac cgcagcccga tggccgagct tgcccgagaa
    17461 gtggaaaagt ggcaaagcaa agtcaatgcc caccttgaaa atatgggttt tggaggctga
    17521 aatggcggca cagacaggct ataaggcgag cgggttttga gacctttgca aaattcccca
    17581 aaatccccta aattcccacc aagacattta ggggatcgcg gttcgggtgt ccgcaccgct
    17641 taatacgtcg tcgtccacga actgacccat ttgctcgaac gccatcgcaa cgcccgtttt
    17701 atggcgcata tggacaactt tctcccaaac tggcaaagca tcaaacaaca gcttaatgcc
    17761 ttggagttat ttgcacaaat atataattta acataatata tattatgcga actatcggaa
    17821 acagttgtac gtgtccctgt ggtctttcca agtaggaaaa ttaaagtatg gacaatgcgg
    17881 ctgaatgtat agcccggagc atccgcgtat ccgaaggtac tgaacgatat gccctgcatc
    17941 cctttcgacg cttccatcca gccggtattg ggaaatacgt tgaccttcaa tacgatatac
    18001 aggcagccga cacacaggat atgccgctgc tttttcatca tttcttctgt caaatccttg
    18061 gaacagttga tttgaaaaca cggctttaca tacgtcccaa ttctctttgc agtgcttgga
    18121 tattttgctg cctgtccaat acattgcttt gcaatgcgtt gatttcttga tggttgatgt
    18181 tgccgccttt tgccagacgt gcttgtgata acattttttg ggcttcaacc aatgctttgc
    18241 gttcgttgct caattctgtt tcgagaatgg agcgtctgct gttgtttgag ggtgcttgtt
    18301 gcggcggggg cgtattggat tttgccggct tggatactgt tttgaccggg gctttatatt
    18361 tgacagcctg tccgccgttt gacggtgatg gtgtcggttc ggatgtttgg ggcgggatat
    18421 agcgttcgct gctgtagttg ccgattgggg gcaaatcggt tgagaggcag cttttggacg
    18481 gcttggtggt gtaaacggtt tctccgttga ttgtgcaggt gtagattttg gccgcattcg
    18541 cacccaatgg gcttgaaatc agggaaaagt tgattaggat taaggggagt tttgatttca
    18601 taatgtgctt gatgctcgga taattatttg attttttggt attttttgta atgctttctt
    18661 ggcgttttac gggcttttct tttcggttgg ttgcttttga ttttctttcg gggctttggc
    18721 agcctgcttg ttctttttcc cggcaggttt tttgtttttc tttttacttt ctatgtgtat
    18781 tttggcttct taactgagtt ttttaatttt caggcggtat ccgcctccct gatggctgct
    18841 gattttaggt aaatccgcat cggcgcacga tcctgctggg gctgatgtat atacgctttt
    18901 gccatttgag ttgcaatggt atacggaggc ttgcgccgcc gcgccggaaa gggacaggag
    18961 acccaaggcg gcaaaaagtc tgatgtttat accggtaaaa ggcggtgata acgcccgaat
    19021 tataccgtta ttggcaggca aagataagca ccctgtccgc gcttctttat cgctcggcaa
    19081 actgtttctc gatttcagtt tcaatccgtt ccaattcttc ttgacaagcc agccaaacct
    19141 cttcgatttg ggcaagttgt gttttgactt ttgtcagcag ggataaggta ttttgcaatt
    19201 tttctttgtt tgcttcaagg taagcgtctt cttgtgctaa aaatgcttca catgccgtct
    19261 gaatttcgga aagctgcgcc atttcttttt cggcacggtc tattttctgc tgtatcggct
    19321 tgccgcgtcg ggctttttcc tgacggattt gcgcttcgat gcgcttggtg tctttgcggc
    19381 tttggctttg tgcggatgct gcgggtgcgg cggcggcgtt ttcctgtgcc aaacgccatt
    19441 ggcggtaatc gttcaaatcg ccgtcgaagt tcttcagacg gcctttgtcg atcaggagga
    19501 agctgtcggt agtcgcttca agcaggctgc ggtcgtgcga tacggcgatt aatgcgcctt
    19561 ggaaactttg caacgcgagc gttaaggcgt ggcgcatatc caagtccaaa tggttggtcg
    19621 gttcgtcaag cagcaacagg ttcggctttt gccagataat catggcaagg gcaaggcggg
    19681 ctttttctcc gccggaaaaa ggttcggttt tctgtaacgc catatcgcca acaaaattga
    19741 agccgccgag gaaatttcgg atttcttgtt cgcgtacttc gggagaaagc tgctgaatat
    19801 gccaaacagg gttttggtcg gcgcggatgg tatcgagttg gtgttgggca aaatagccga
    19861 tattgagttt ttcggaacgg acgatgctgc cggagagcaa atcgattttg cccgccaagg
    19921 ctttgataaa tgtagattta ccgctgccgt tgacacccaa tagcccgtag cgtgcgccgc
    19981 tttccagcga cagggtaatg tcatgcagaa cggttttgcc ttcgtaaccc aaatcagcgt
    20041 gttctagctt taacaaagga ttgggcagat gatcgggatg gtaaaactca aaggaaaact
    20101 cgctgtccag atgcgcgggc gcaacgcgtt ctagctttgc caaagccttc atgcggcttt
    20161 gcgcttgaac ggctttggtg gctttggctt tgaagcggtc gataaaggat tgcaaatgtt
    20221 tgatttgcgc ctgctgtttg acataggcag cttgttgttg cgcgagacgc tgcgcgcgtt
    20281 cgttttggta aaaatcgtaa ttgccgccgt attgcgtgaa tttttgctgc gataattcaa
    20341 tggtttgggt agttgccgcg ttgagaaaat cgcggtcgtg ggaaatgatg atttgcgtgc
    20401 agggtaaaga agcaagatgg ttttccagcc acaagacggt ttccaaatcc aagtggttgg
    20461 tcggttcgtc caaaagcagc aaatcggcgc ggcaaatcag ggcttgggcg agattgaggc
    20521 gcatacgcca gccgccggaa aaggatttga cggggcggct gtgttcttct tgtgaaaaac
    20581 ccagcccgtt caacaatttt gccgcgcggg ccggcgcggt ataagcgtcg atttcttcca
    20641 atttggcatg atattccgcc tgcttcatgc cgtcattttg cgcttccgcc tgcctcaatg
    20701 ccgtctgaaa agcctgcaac tcggcatcgc cctgcaaaac gtaatccaaa gcggaaatat
    20761 ccaaatcggg cgtttcttgg gaaacggaag cgagccgcca gtttttcgga atcgagacat
    20821 cgccgccgtc ctgagtgatt ttacccttga ttaaggcaaa caggctcgat ttgcccgttc
    20881 cgtttttgcc gatcaaaccg acgcgatgac cgggattgac ggtagcgttg gctttgtcga
    20941 gcaggacttt caaaccgcgt tgcagggtga ggtttttgat ttcaatcata acggaaacat
    21001 cgtcgggcgg aaaaagcccg tattttacct gaaagtcagt gccgatgccg tctgaaatgg
    21061 gaaatttacg gctgaagcca agcccaagcc ctgcgccctt ccgagtgcag gaaaaccaat
    21121 gtcctgaatg ccgaatcggt attcatacat tccacgccga ttccgattcg agaaaaatcc
    21181 gccatgattt tgggatggat aaactcctga gccgcgcccg tcccgataat caatatttcc
    21241 ggatagtcaa caggtttgat gtcggacaac aggttttccg gagtcagatc ggacaaggtt
    21301 cggcattgcg acaggcagac cgaatcctta tgtacaagca cgggtttatg gaaactttga
    21361 cccgccaatc ggatttcacc cgaccggtgg ccatactctg taaaatgtcc gtctatcgga
    21421 ttttcttcaa acaacatttt tttaccccgt cgccgcatca tctacaccga aaggggtgca
    21481 aaatcaggcg aattcatgta ggattggcag atttcatctg acccgcctgc cgatttcaga
    21541 ctgcatttga ttcaaagtgc ggcacaatta tatcggcagc ggatattttc gtctttcaat
    21601 atttacattt cagtcggctt acaaggagac acaatgaagc cagtaaacat cggtctttta
    21661 ggtttaggta cggtcggcgg cggtacggct gccgtgttac gggacaatgc ggcggaaatt
    21721 tcccgtcgct tggggcgcga aatccgtatt tctgccgtgt gcgatttgag tgaagaaaaa
    21781 gcccgacaaa cctgcccgtc cgcagccttt gtcaaagatc cgttcgaact ggtcgcacgt
    21841 gaagacgtcg atgtcgtcgt cgaattgttc ggcggtaccg gcattgccaa agatgcggtg
    21901 ttgaaagcca ttgaaaacgg caaacacatc gttaccgcca acaaaaaact gctcgccgaa
    21961 tacggcaacg aaatcttccc gctggcggaa aaacaaaacg tcatcgtcca atttgaagcg
    22021 gcagtagcgg gcggtatccc aatcatcaaa gccctgcgcg aaggtttggc ggcaaacagg
    22081 attaaatcca tcgccggcat tattaacggc accagcaact tcatcctctc cgaaatgcgc
    22141 gaaaaaggca gcgcgtttgc cgatgtactg aaagaagcgc aggcattggg ttatgccgaa
    22201 gccgatccga ccttcgacat cgaaggcaac gatgcgggcc ataaaatcac catcatgagc
    22261 gcactggcat tcggcacgcc gatgaacttt tccgcctgct acctcgaagg catcagcaaa
    22321 ctcgacagcc gcgacatcaa atacgccgaa gaacttggct atcgcatcaa actgttgggc
    22381 attacccgca aaaccggcaa aggcatcgag ctgcgcgtcc accctaccct gattcccgaa
    22441 agccgcctct tggcaaacgt caacggcgtg atgaacgccg tgcgcgtcaa cgccgatatg
    22501 gttggcgaaa ccttatatta cggcgcgggc gcgggcgcat tgccgaccgc ttccgccgtg
    22561 gttgccgata tcatcgacat cgcccgcctg gttgaagccg ataccgccca ccgcgtaccg
    22621 catctggcgt tccaacccgc gcaagtccaa gcgcaaacca tcctgcctat ggacgaaatt
    22681 accagcagct actacctgcg cgtccaagcc aaagacgaac cgggcacgct ggggcaaatc
    22741 gccgcgctgt tggcacaaga aaacgtgtcc atcgaagcac tgattcaaaa aggcgtgatt
    22801 gatcagacca ctgccgaaat cgtgattctg acccacagca cggtcgaaaa acacatcaag
    22861 tcggcaatcg cagccatcga agcactggat tgcgtggaaa aaccgattac catgatccgc
    22921 atggaaagcc tgcatgactg agccgaaaca cgaaatgccg acggaagagc aggttgccgc
    22981 gcgcaaaaaa gcaaaagcca aaatccgcac catccgcatt tgggcgtggg tcattttggc
    23041 gttgctcgct ttaaccgccc tgctctccca atgcgcgatg tccaaaccgc aggcaaaaca
    23101 gaaaattgtc gagtcttgcg tgaagaatat tccgtttgcc gaaaaatggc aaaacgattt
    23161 gcgggcccgc ggtttagatt caaacaatac ccgcctcgcc gtcgactact gcaaatgtat
    23221 gtgggagcag cctttggaca gattgagcga gaaacagatt agatccttcg gcaaactcgg
    23281 cgcacaagaa cagcttgacc tgctcggcgg cgcaaatgcc tttgaagcac gtgacaagca
    23341 gtgtgttgcc gatttgaaat cagaataatg tggaccgata aaaaagccga ttctttaaag
    23401 aatcggcttt tttcataaaa aacggcttac agtgcgtctt tcaatgcttt acctgcacgg
    23461 aatttaggcg ttttggcggc ggcaatggtc agaggctcgc cggttttggg gttgcggcct
    23521 tggcgttccg cacgttcgcc cacgtagaaa gtaccgaaac cgaccaaagt aacggtgtcg
    23581 ccttgtttca gggcggtggt tactgcattg gtagtggcat ccaaagcttt ttgtgcggcg
    23641 gctttggaaa tgtcggcttc ttgagcaatc gcttcgatca attcagactt gttcacaatc
    23701 agtcccttcc tgtcttaaaa aatgatgaaa tgcccgaata ctcggggttt gtactgcttg
    23761 agcaactttc gctttatagc aattctgaaa ttgccgtgtc aagcaaaaaa tacggaatca
    23821 ccctatttga caggctttca ggacgaaacc gcatttttac aacacatttc ctgcgtttca
    23881 atgtttggtt gccctgctgc ggggttttgg ttttgaagcg gattccgccg ccgcttccgc
    23941 accagaaggt tctgcccaag gctcaggctg gctttccaaa cccagagcca atacctcgtc
    24001 tatccatttg accggatgga tggtcaggcc ggttttcacg ttttcaggga tttcttccaa
    24061 gtctttgagg ttgtcttttg gaattaaaac gtgtttgatg ccgccgcgaa gcgcagccaa
    24121 cagtttttcc ttcagaccgc caatcggcag gacttcgccg cgcagggtaa tttcgcccgt
    24181 catggcaaca tcggcgcgca ccgggatttt ggtgaatgca gacaccatcg ccaaagtcat
    24241 ggcaatgccc gcactcggac cgtctttcgg cgtcgcacct tcgggaacat ggacatggat
    24301 gtcttttttc tcgtaaaaat caggagccaa gcccactgat tccgcgcggg agcggacaac
    24361 cgaccacgct gcggacacgg attccttcat cacatcgccc aactggccgg tgcactgaat
    24421 cacgccctta cccggcaatg ctgcggcttc gacggtcagc aattcgccgc cgacttccgt
    24481 ccacgccaaa ccggttactt gtccgatacg gttttcgctt tcggcaacgc cgtaatcgaa
    24541 gcggcgcaca cccaaatagt cgtgcagatt tttctcattt actttaaccg ccctgggctt
    24601 ggcttttccg gtttttttgg tttttgagtc ttcgtccaag gtaatctgca tcaccacctt
    24661 gcggcagatt ttggcaatct cgcggtcgag cgaacgcacg cccgcctcgc gggtgtagta
    24721 acggataata tcgcgcaccg cgctttcttc gattgccaat tccccttctt ttacgccgtt
    24781 gcgcttcatt tgcttcggca cgaggtactg catcgcgata ttgatttttt cgtcttcggt
    24841 atagccggac agacggatga tttccatacg gtcgagcagc ggtgtcggga tattcaggct
    24901 gtttgaagtc gcaataaaca tcacatcgct caaatcgtaa tccacttcgg cataatgatc
    24961 ggcgaacttg ttgttttgct cgggatcaag cacttcgagc aacgcgctgg cgggatcgcc
    25021 ccggaagtcg ctacccaatt tgtcgatttc gtcgagcagg aacaatgggt tttttacgcc
    25081 ggcttttgcc atattctgca aaatcttacc gggcatggag ccgatatagg tgcggcggtg
    25141 tccccggatt tcgctttcgt cgcgcacgcc gcccaaagcc atgcggacat atttccgccc
    25201 cgttgctttg gcgatggatt cgcccaaaga ggttttgccc acgcctggag ggccgaccag
    25261 gcacagaatc gggcctttga gtttgtccat acgtttttgg acggcgaggt attccaaaat
    25321 ccgttctttg actttttcca ggccgtagtg gtcggtatcc agcaccaatc cggctttggc
    25381 gatgtctttg ctgacgcggg attttttctt ccacggcagt tcgagcaggg tgtcgatgta
    25441 gttgcgtacg acggtggatt cggcagacat cggcggcatc attttgagtt ttttcagttc
    25501 ggacaggcat ttttcttccg cttctttgct catccccgcc tttttgatgc ctgcttccaa
    25561 ggcatccagt tcgccgtttt cgtcttcttc gcccaattct ttgtgtatcg ctttaatctg
    25621 ttcgttcaga taatattcgc gctgggattt ttccatttgg cgtttgacgc gtccgcgtat
    25681 gcgtttttcg gcctgcataa tgtcgagttc ggattccagc tgtgccagca ggaattccat
    25741 ccgtttgccg atttcgggaa tttccaaaat ctgttggcgt tgcgccagtt tcaactgcaa
    25801 atgcgctgcg accgtatcgg ttagccggct gttttcggca atgccgttaa tgctgccgat
    25861 aatttcggcg gggatttttt tattgagttt ggcgtattgt tcaaactgcg ccaacagggt
    25921 gcggcgcacg gcttcgaggt cggtattgcc gcccgtgtct tcttccacga ccgtctctat
    25981 atgggaaacg aacagaccgc ccgtgtcttc aatggtcaga acacgtccgc gatacagccc
    26041 ttcgaccaat acttttaccg tgccgtcggg tagtttcaac acttgcagga cttgtgcgac
    26101 cgtaccggtc tgatacaggt cggcggcaac cggttcttct agcgccgcat cggtttgcgc
    26161 caacaggaaa accggctcct cgcgggtaat ggcgttttcc agtgcggcga tggatttcgg
    26221 cctgccgaca aacagcggca gaaccatatg cgggtaaacg acgacatccc gcaaaggaag
    26281 ggttgccaag gcggcatatt cctcaaaatg cttttctttt tgtgtcatag gtactctctt
    26341 gtgtctgaca gattgccgat tttcgcgtac attggggttg aaggtattat ttcaagcata
    26401 tgtggtttat ttatggagtt tgatgcgatg ccgtctgaaa cattccggct tcagacggca
    26461 tgggcttgga aagacaaggc gggaacaaaa aactgttctg tgttgccgct ccttgctgta
    26521 ccatccgtat ggtttgcggt tctgccgccc tattttcaaa acatgacgca ggtattccat
    26581 gtcttctttt atttttcccg ataacgggtt cgaatggcgc aacgaaagtc tgcaaaagcc
    26641 gcccaaaggt tggcattatg tccgcgaaag tggtgcaaac ggcattttga aggctgccta
    26701 tcaaaatatt gcaactgtct ggcagggcga tttccacaat gccaaacagg tgctttccgc
    26761 aatgaagaag aaggtccgca aacctgccgc cgtccgttcc gatgcggata ttgccgccct
    26821 tttccacgcc caccgtatga agcaggcgca gcagagccgt attctgaata tgcttgccgt
    26881 tgaaatccgc cccggttttg tgttggacaa caaacgcgcg cccgatatac gcgccgccct
    26941 gctcgacgtg tacggagagg cggacggcaa accgtttttc ctgccgctca atctgctgct
    27001 ggggtttatg ggtgcgcacg agtggcataa gaaaggggtt gccgttccgc agctgggcgg
    27061 cagcatacac gttcctttcg gcgtattctc gccgttgcgc ggcgaatacc tcgacctgct
    27121 cgcccatgcg ccgtcaacgg gttttcagac ggcattcgat atcgggacgg gctcgggcgt
    27181 gcttgccgcc attttggcga aacagggcat tccttccgtc atcggcacgg ataccaatcc
    27241 gaaagccgtc gcctgcgccc gtgccaatat tgcccgtttg ggctttgaaa aacaggttga
    27301 gatacgggaa accgatctgt ttcccgaagg gtttgccgat ctgattgtct gcaatccgcc
    27361 ctggcttccc gccaagccga cttccgccgt cgaatccgcg ttatacgacc ccgaatctgc
    27421 gatgctggct gcgtttttgc gggatgcgcc gaaacatctg aatcccgacg gagaaatccg
    27481 cctgattatt tccgaccttg cagagcattt ggggctgcgc cctgccgatt ttttggaaaa
    27541 ggcatttatc cgggcgggtt tgcgtgttgc cgatatgatg aaaaccaagc cgaagcacaa
    27601 aaaagccgcg aatccgagcg atccgcttgc ttttgcgcga acccgggaaa ccactttcct
    27661 ataccgtttg aaaaaggcat aaggggcggc ggcgcggcat tcgggcggat tattcttgtg
    27721 aaaatacccg ctcgagcata ctgcccaatg ccgtctgacg cgttttgaca gtggcggcag
    27781 cttgccggaa ggtttcttct ccgccgaaga atacgaactt ctccctcgcg cgggtaatgg
    27841 cggtatataa cagctcctta ctcaatccgg acaatgcatc gtccccttcg tccgaaggtg
    27901 cggcggaagg cggcagcagc cagacttccc gatattccga accttggctt ttgtggacgg
    27961 tcatggcgaa tgcgggttcg aaatcgggca ggcagcttac cgctaccttt ttaaatccgt
    28021 ccgcatcggc aaaataggcg gcaaggctgc cctgccgtcc gacatcttcc ataatcaatc
    28081 cgatgtcgcc gttgaacagt tcaagcgcgt agtcgttctg tctgatcata atcggttctc
    28141 cggcgaaata ggcctgatgt tccggtatgt tcattttgcg gcgtacatgg ctgcaatagg
    28201 cttcgttgaa gtcttccgca tcctgccgcc aagctgccag gaccacgata tccgagatgc
    28261 ctgcgtatgc ggcttcgata ttgccgtctt ttaccgcctg ccaataggct ttgtgcgccc
    28321 ggtacaacct ttcgactcga gcgttcggac tgcattccga atgttccagt tcgtccggaa
    28381 accggtcaaa caatgcccac gccccctcat cgcccgatac ggcggcacgg gcaaggcagc
    28441 cgatgccgct gttgtcgccg aagcggtggc tgaacgacag atgggcggtg ttttgcgcca
    28501 acaagggcgg atttgcactg acgctgaaac cgtgttccgg aaggaagccg gccagccttt
    28561 ggtgcgtttc tccgtccaaa acggtttttt gcgacaggac ggacagcacg tccccgattc
    28621 cgacggacgg gagctggttt tcatcgccca gcagaatcac gcgcgcgccg gttttgaccg
    28681 cttttaaaag ttgcaacatc aataccgtat ccagcataga ggcttcatcg ataaccaata
    28741 cgtcaaacgg cagcgggtaa acagggttga acgccgcctg cattttgggc gggcgcagct
    28801 tcagcagtcg gtggacggtt tgcccttcca gtttgagcaa atggcggcgg acggcctccg
    28861 gcgcgtcaaa accgttgatt gcacggtgca gcgcgcgcgc catatgtgcc gccgctttgc
    28921 ccgtcggtgc ggcaagcgcg atgttgggaa gattttcgtc ttcaccgcaa atcagcgcca
    28981 gcagtttggc aaccgttgtc gttttgcccg ttcccggccc gccggtaatc accataaaag
    29041 actgcaacag tgccaaggcg gcggcatcgc gctgcccttc gctgcccgtg ccttgaaacc
    29101 attttgcgag gttttgcctc gcgcctgccg cgtcgggggc ggacgtgtcg gctgccgcca
    29161 agcgttttat ctcggcagcc aaatcgtatt ccaactgcca catcctgccc aaaaacagcc
    29221 ttctgccttc caaaatcaaa ggcgcggcgg atgttccgac cacgggtgcg agtgccgaca
    29281 gcgcgtcagc ctcgccaccg ctcaaacgga taaacgaatg accgttttgc aatgcctgaa
    29341 acaggcgttc ggtgcagttt gcaagcactt cgtcgctgga acccgcatag cgtgccaaaa
    29401 accagattgc cgcccttgcc gccgcttggg caaattcatc tgtctgccgt tccatcgtat
    29461 tccttgtcga aatgccgtct gaaggcgtgg ggcttcagac ggcgcggtgt tgtttcggct
    29521 gtttaggcgt ttgcgccctg tttggggtgc aggctgccgt ctttcatgac catcacgcgc
    29581 ccgaagcggc cggcgagttc gtcgtcgtgc gttacgacca caagccccgt tcccaattct
    29641 gttttcagtt ccagcatcat atccaaaaca ttcctggcgt tcgcacgatc gagattgccg
    29701 gtcggttcgt cggcaagcag gcatttgggt tgcgtaacca aggcgcgtgc aatggcggca
    29761 cgctgccgct caccgcctga aagttcgccc gcgcggtgcg tcgaacggtg tttcagtccg
    29821 accttttcca gcatcgccat tgccgcctcc gcagcctctt cacggctttt tttgccgatc
    29881 agaagcggca tcatcacatt ttccagtgcc gaaaattcag gcagaagatg gtggaactgg
    29941 tacacgaaac cgagatggcg gttacgtaaa tcgcccaaac gccgctggtt taaggtacgc
    30001 aaatcctcgc ccatcagcag caccctgcct tcagacggca tatccagccc gcctagaata
    30061 tgcagcagcg tcgattttcc gctgcccgaa gaaccgatga tgccggtgct ttcccccgcg
    30121 cggatttcca aatccaagcc gtgcagcacc agaacgtcca aaccgccgtc ccgatagcgt
    30181 ttgcccacgc cttcgcattt caaaatcaac tcactcataa cgcaaagcct ccgccggttg
    30241 ggtttttgac gcgcgccggc tcgggtagag cgtcgccacg aaagacagcc ccaaggaaat
    30301 gcaggcaatc agggcaacgt cgcccatatc gacatcgctg ggcaggtagt cgataaaata
    30361 aacctgcgaa ttgatgaggt ggacaccgag caggttttca aaaaacgcca cgaccctgcc
    30421 gacgttccaa cccaaaagca cgccgcagac cacacccgcc aacgtgccga aaaagcctga
    30481 aaacgcgccc tgcaccataa aaatcttcat cacgccgcca ggggaaagac ccaaagtccg
    30541 taaaatcgca atgtccgcct gcttttccgt aaccgccatc accaaggaag agacaaggtt
    30601 gaacgccgcc acggcgataa tcagcgtcag gatgatgaac atcatccgtt tttccaactc
    30661 gaccgcctca aaatagctgc ggttgctgaa cgtccaatcg cgtacccaaa ccgtatccct
    30721 ttgcgcctcc ggaatcagct ttgccgtcaa ggcgggggcg ttttgcgggt cggcgagttt
    30781 cagccgcagc cccgcaactt ccttatccaa gcggtacagt acgcgcgcgt cttggatatg
    30841 cgtcatcgcc aatgagttgt ccacttcgta aacacccgtt ttaaccagac cgaccacggt
    30901 aaactgtttc aacctcggta cgactccggc gggcgtaaca ttgccctccg gcgtgatgac
    30961 ggtaacttta ttgccgactt ccgcccccaa agcctccgcc aagccgacac cgaggataat
    31021 gtcaaactcg cccggaatca ggtcttcaaa tttgcctgcc ggcattttgt cgccgtattc
    31081 caccactttg cgctcttcag acggcaaaat gccgcgcatc tgcacgcccc tgatttcgcc
    31141 cgcattggcc agcaatgcct gattggaaac atagggcgcg gcagccaaaa tacctttgcg
    31201 gttttcggta aaccgaagca ggttgcgcca atccgtatcc gtattgtcga tatagccgat
    31261 ttcggcgtgc ggcgcgacat tcaggagctg cccgcgtatt tctttctgaa agccgttcat
    31321 aaccgacaag acgacaatca gcgcggttac gcccaaggcg attccggcaa tcgaaaccat
    31381 cgtgataaac gacataaagc cgttgcgctt tttcgccctg agatacctca agcctatcca
    31441 agcctctaga gaaaacataa cgctacctta aaaatgtctg caaacgtgcc gccccggacg
    31501 gcggtttggg ggcggcggca aaagtttatt gtaccgtaaa acccaggcag cgtccgaacg
    31561 cccgagtgcg ggggacgggg cggcagagcg ggcggaaaac ttgcacaacg cgtcaaactg
    31621 ccctatcctt tccttcagaa aaaccgtttc ttgaggaaaa caatgaatat ccgaactgct
    31681 tttgctttgt gcgccatcgc cttatccgcc gctgcggctg cctacgccaa agaaatcaaa
    31741 atcgatgcca acaacacgcc ttattccgaa gccgacgcgc aaaagctggc ggcaacggca
    31801 gtcggtatgg gtgttaagga acctatcagc ctgaacggcg gcagcggcag cattaccgtg
    31861 tccggcagca gcgcgacgca gtgcgtgttc aaagtcggca acggaggcgc gttgcagatt
    31921 aaagggctaa actgcaagta aaccgcccgg aaaaatgccg tctgaaggct tcagacggca
    31981 ttttgcattg gcggcgttat gccccgcctt ctttaatcag gcggcgttcg tacaccgcct
    32041 gcgccagcgt tcccgcatcg acatattcca attcgccgcc caaggggatg ccctgcgaca
    32101 gcctgctgac tttgtaaggc aggtttttaa aaaactcgga caggacatac gccgtcgcat
    32161 tgccttctgc ggtaaaagcg gttgcaataa tgatttcttc gacttccccg ccgcccagcc
    32221 gttgcgccag cctgtccaat gcgatggcgg atacgtccat tcccagtgcc gtattgattt
    32281 gccccatcag gacgaaatac agcccgtcgt ggcagtttgc cgcttccata ttcgacacgt
    32341 cggcaggcat atgcaccacc atcagccgcc gcccgtcgcg tgtttcatcg gcacaaatat
    32401 cgcacaatcc gccttcgcaa aacgtgttgc acatcgcgca atggtaaacc tgcttcaatg
    32461 ccgtctgcaa ggcatccacc agtttttcag cctctttgcg cttgtgttgg agcaaatgat
    32521 acgctatccg ctgtgccgat ttcggcccga cgttgggtaa aaccttcagc gcgtcgatca
    32581 atccttggaa ggcatcttgt tttttgtggc tcatcatatt ccgccgtatg ggaaaacggc
    32641 cggaatattc cgaccgttat tttgtcaaca aaagtgtcaa ttactgaccg tcgccgttgt
    32701 cgaccgattg cgctcctttg gtctgtttga ttttgccgtt gaaataacgt atcaacaagt
    32761 cgaaagtatt ggcagactgc tgttgcgcca aagcctgttt tgcaagcgga agctgtgcgg
    32821 cgatatcatc cggcggggtt acagcctgta cttcgacaat cacgggtgcc ggcagaccga
    32881 tcagcctgac gtaggcgggt ttgccgtttg ccggttttgc tttcagcagt tccgcataag
    32941 cctcgggcgg catggactgc cttgcctgct gtgcgcccaa aacggacact tccgaccatt
    33001 tcacgtcaac agccttgccg ccgttcagtt gggtaagcac gtcttttgcc ttgttttcgg
    33061 caagtttggc ggcttcggca cggatataag cctgacgtac cgcgtctttg gcttcggcaa
    33121 acggcagggt tttctcttcg cggacttctt tggcgcggac gacccacgcg gtttcgctgt
    33181 tgatggtcag cacttcggaa ttgtgttttt tcttcaatac gtcgtcgctg aatacggcat
    33241 tgatcaggtt ttcgggcata ccggacattt gcgcatcctg cctgctcagc caagtttctt
    33301 gggtttcgac tttcaaaccg ctgtttttgg cggcttcggc aagcgaggaa ggatggttga
    33361 acgcgtcatc gcccagcttt tcttttgcct tattgaagtc ggtaaccgcc tttttcattt
    33421 tcaattcgtt ttcgacggcg gctttttcct gctcgaaaga aggtttggct tcatttgccg
    33481 gcaaacgcgc cacgcgctct tcaaacgcat ttttcacttc tgtttcgctg acggtctgtt
    33541 tgtctgcaaa gtctttcaga ttcaaggcga catattccaa tttgaccgct ttgggaagca
    33601 ggtagtcttt tttgttcgca ttataaaatt tctgcaaatc ggcttcagac actttgactt
    33661 gggcgatgaa ctcgtcgggg ttgaaagtgt gcgaacggat ggtgcggttg acctgcgtca
    33721 gcctgatcag ctgttccgcc tgcgcgtcgc cgaccaatac gccgttttgg acgaggttta
    33781 ccaaattctg caaggcaaac tgatcgcgga tttcttcgac aaactggtct tcagacatat
    33841 ggcgttgcga caggtagcgg tttaaaagcg cgtggtcgaa tttgccgttt gcgtcgtgga
    33901 aattgggatc atccacgata atctgcttga tttgttcgga agaaaccgaa atgcccatca
    33961 gcttcgcgcc ctgtttcagg taggcgcgtt gcagcaggga ttggaacacc gcgtcgcgcg
    34021 aagggccgcc gccgtccgcc tgttcgttct gtatggcgtt gttgatggag tggtcgctga
    34081 ttttttcgtc gcccacttgg acgatgtagt cggcacccgg atgggatacc gtgctgaccc
    34141 cgaagccgac gaaggttaat gcaatcaggc ccaaaaggac ttgggcgggc gttctgtatt
    34201 tttcgatgga atggaacata ttttaaatcg ggatatagaa tgggaacggg aaattcaagt
    34261 cgggtattgt aacggttttt atccctgtct gcacggggct tgccggttga agatgccgtc
    34321 gtaggtttct tcgctgaagc cggcgtaaac cttgccgccg cactccaata cgggacgctt
    34381 gatcaggctc ggcatttcgg acatcagttt gacggcctcc gctgtcgaga acagggcttt
    34441 ttgctgtgtt tcggcatcga gtttgcgcca gcttgtcccg cgtttgttga gcagggttgc
    34501 caaaggcact tgttccagcc acgagcagat ttccgcttcg gaaggcacct gttttttaaa
    34561 atcccgaaat tcaaactcca agccgtatcc ggcaagccgg tttttggctt ttttgaccgt
    34621 atcgcaattt gggatgccgt gaaggattat catttggaaa ccttttgtct gaaataataa
    34681 aacggatatt ttactataag tgtctgaaaa tttgcccgtc tgtttcagac ggcggggcgg
    34741 ttatgttaca atccgaaaat tcgaaaaatt taatctcttg ttcaataaag gctttaccaa
    34801 tcatgatttc taccaacggc atcaccatgc agttcggcgc gaagccgctg tttgaaaacg
    34861 tatccgtcaa attcggcgaa ggcaaccgat acggtttgat cggcgcgaac ggctcaggca
    34921 aatctacttt catgaaaatc ctcggcggcg atttggaaca gacggccggc gaagtggcga
    34981 ttgaaaacgg cgtgcgtttg ggtaaattgc gccaagacca gtttgcctac gaagatatgc
    35041 gcgtgctgga cgtggtaatg atgggtcaca ccgaaatgtg ggcggcgatg accgaacgtg
    35101 atgcgattta cgccaatccc gaagccaccg aagacgacta catgaaagcc gcagaactgg
    35161 aagccaagtt cgccgaatac gacggctaca ccgccgaagc gcgtgccgcc gagttgttga
    35221 gcggcgtggg catttccgaa gatttgcaca atgcaaccat ggcagaagtt gccccgggct
    35281 tcaaactgcg cgtattgctg gcgcaggcgc tgttctccaa gccggatgta ttgctcttgg
    35341 acgaaccgac caataacttg gacattaata ccatccgctg gttggaaggc gtgttgaacc
    35401 aatacgactc cacgatgatt atcatcagcc acgaccgcca ctttttgaac gaagtctgca
    35461 ctcacatggc ggatttggac tacaacacca tcaccatcta tccgggcaac tacgacgact
    35521 acatgctcgc ctccgcccaa tcgcgcgaac gcgccctgaa agacaatgcc aaagccaaag
    35581 agaaactgca agagctgcaa gagttcgtcg cccgcttctc tgccaacaaa tccaaagccc
    35641 gtcaggcaac cagccgtctg aaacaggccg acaaaatcaa atcggagatg gtcgaagtca
    35701 aaccttccac ccgtcaaaac ccgtatatcc gttttgaagc cgatgaaaaa gccaagctgc
    35761 accgtcaggc tgtggaagtt gaaaaactgg cgaaacgctt tgaaacccag ttgtttaaaa
    35821 acctgaactt catccttgaa gcgggacaac gcctcgccat catcggcccg aacggcgcgg
    35881 gcaaatccac cctgctgaaa ctcttggccg gcgcgtacaa ccccgaatat tcagacggtc
    35941 tgctgccgga cgaaggcagc atcaaatggg cggaaaaagc cagcgtcggc tactatccgc
    36001 aagatcacga aaacgacttc gatgtcgata tggatttgag cgaatggatg cgccaatggg
    36061 ggcaggacgg cgacgacgaa caagtcatcc gcggcacttt ggggcgtttg ctcttcggca
    36121 gtaacgatgt cgtgaaaaaa gtgaaggttc tctccggtgg tgaaaaaggc cgtatgcttt
    36181 acggcaaact gttgctgttg aaacccaatg tcttagtcat ggatgaaccg accaaccaca
    36241 tggacatgga aagcatcgaa tccttgaaca tggcgctgga aaaatacaac ggcacgctga
    36301 ttttcgtctc ccacgaccgt cagttcgttt cttccctggc tacccaaatc attgaattgg
    36361 acggcaaagg cggatatgaa cactacttgg gcgattacga aagctatctc gagaaaaaag
    36421 gcgtagcata accgccggtt ggaacaatgc cgtctgaagc ggcttcagac ggcattgttg
    36481 ataactttaa aataggaagc atatgcagac ttatctcgtc ggcggtgccg tccgcgatta
    36541 tcttttgggc ttgcccgtca aagaccgcga ttgggtggtc gtcggcgcag acgcacaaac
    36601 catgctggcg caaggcttcc agccagtcgg caaagacttt cccgtgtttc tccatcccga
    36661 aacacacgaa gaatacgccc tcgcccgcac cgagcgcaaa accgccaaag gttacgtcgg
    36721 tttcagtttc cacgccgaca aagacgttac gctggagcag gatttgatgc gccgcgacct
    36781 gaccatcaac gcgatggcgc aagatgcgga cggcaagatt atcgaccctt tcggcggaca
    36841 acgggatttg gcggcaggca ttttgcgcca cgtttccccg gccttcgccg aagaccccgt
    36901 ccgcatcctg cgtactgccc gctttgccgc gcgttacagg tttgaaatcg ccgaagaaac
    36961 cataaagctg atgcggcaga tggtggaaaa cggcgaagcg gacgcattgg ttgccgaacg
    37021 cgtctggcag gagttggcga aaggtttgat ggaaaaaaat ccgcgcaaaa tgattgaagt
    37081 gttgcgcgaa tgcggcgcgc tcaaagtctt gctgcccgaa gtcaatgccc tcttcggcgt
    37141 gccgcaacgc gccgactacc atcccgaaat cgacagcggc atccataccc tgatgacgct
    37201 gcaacgcgcc gccgatatgg gcttgagcct gcccgaacgc tatgccgccc tgctgcacga
    37261 cttgggcaaa gccaaaacac cgtccgacat cctgccgcgc caccacggac acgacctcgc
    37321 cggtgtcgaa cccatgcgcg aagtcaatca gcggctgcgc gcgccgaaac attgcgccga
    37381 gcttgccgaa ttggtttgcc gttggcacat tattttccac caagtcggac agcttaaaag
    37441 ccaaaccatt ctgaacgttt tgaaaaaaac cgacgctttc agacgacccg aacgctttca
    37501 gacggcattg aacgtctgca ttgccgacac gcaaggccgt ctgaaccgcg aacacacgcc
    37561 ctacccgcaa cgcgcgcact ggctcgcctt actcgaagcc gccaatcagg cggattcggg
    37621 caaaatcgcc gccgaatgcc gcgcgcaggg aaaagcgcac cttatcgccg aacaaatcga
    37681 ccgggcgcgg ctggcacaaa tcgccccatt gcaaaaagcg tttcgagcgg cgcaagacaa
    37741 aacagaaaaa cattaaaacg tccaatgcag ccacttttat agtggattaa caaaaatcag
    37801 gacaaggcga cgaagccgca gacagtacag atagtacggc aaggcgaggc aacgctgtac
    37861 tggtttttgt taatccacta taaagttttg aggacgatac ccaatccaag ctttgcaaca
    37921 gccgccgcca tatccgctat aattcacgct tcagccattc cgcccccgac ataaaatcat
    37981 gaccctgaaa accgatttat tgcctaaaat caacaacgaa gattatcaac gcctcatcct
    38041 caaacacagt gcggaattta gcggtggcga aatccgcctg ttgaacgaaa tcctcgaaaa
    38101 attcaatttc gacgttgttc aggcgcaggc attggcgcaa gccgtcatgc agcaaatccg
    38161 cttcgacccc aacgcctacc acatcgacag cgacgacgaa gacaccaccg gcatctgccc
    38221 ccactgcatc aacccgccta tgccgcccct gcgcgactat ctcgtttggc gcgaaacgcg
    38281 cggataaaac gcttttgacc gttatctttt caatgccgtc tgaaacgccg ccgaccgttc
    38341 ggacggcata cccgataaag ggaacactat gctgcaaacc gacaacctga ccgccgcgca
    38401 accgcaacgc atcgttgccg cccaaaccgc ctccgcacag gaagaactgc tcgaacgcgc
    38461 cctccgcccc aaaacgctgg acgactacat cgggcaagac aaagccaaag aacagcttgc
    38521 cattttcatc caagccgcca aaaaacgcgg cgaagcactc gaccacgttt tgctcttcgg
    38581 cccgcccgga ctgggcaaaa ccacactggc gcacatcatc gccaaagaat tgggcgtaaa
    38641 tttgcgccaa accagcggcc ccgtcctcga acgcgcaggc gacctcgccg cccttttgac
    38701 caaccttgat ccgcacgatg tattgttcat cgacgaaatc caccgcctca gccctgttgt
    38761 cgaagaaatc ctctatcccg cgctcgaaga ctaccggctc gacattatga taggcgaagg
    38821 acccgccgcc cgttccgtca aaatcgacct gccgcccttc acgctcatcg gcgcgaccac
    38881 ccgcgccggt atgctgacca atccgttgcg cgaccgcttc ggcatcgtct cccgccttga
    38941 gttttacgaa aaccgagacc ttaccaccat cgtcagccgt tcggcacaac tgttgcagct
    39001 cgatatgtcc gaagaaggcg cggaagaaat cgccaaacgc agccgcggta cgccgcgcat
    39061 cgccaaccgc ctgttgcgac gcgtgcgcga tttcgccgac gtgaaaaaca acggcacaat
    39121 cgacggcggc atcgccgatg ccgctttaag tatgctggac gtggacgcgc aggggctgga
    39181 cgtgatggac aggaaatttc tcgaagccgt tttgcacaaa ttcggcggcg gcccggtcgg
    39241 tttggacaat gttgccgccg ccatcggcga atctacagac accatcgaag acgttatcga
    39301 accctacctt atccaacaag gcttcctgca acgcaccccg cgcggcagga tggcgaccga
    39361 acgcgcctac ctgcatttcg ggctgcccgt cgaaaaataa cgcaatgccg tctgaaacag
    39421 agctaatttt cagacggcat ttctatttca atcattggcg caaggttcag cctgccgctt
    39481 ttttccagtt ccgccctcat cgcatcaatc accgccttat agtctggttt gccgaaaatc
    39541 gcagaaccgg caacaaaggt atccgcacca gctcgggcaa cggcggcaat attgtcggtt
    39601 ttgatgccgc cgtccacttc gatggcgatg tgccgcccgc tttgtgcttc gtaccgatcc
    39661 agcatcgccc gcacccggcg gattttttca agggtgtgcg ggatgaagct ttgtccgccg
    39721 aatccggggt tgaccgacat cagcaaaacc atatccagcc tgtccaatac gttttccaac
    39781 agatatacgg gcgttgccgg attcaacacc agccccgcct gacagcccat atcacgaatc
    39841 aggctcaagc tgcggtcgat atggcggctc gcctcgggat ggaacgtgat gattgatgct
    39901 cctgctttgg caaacgactg aatcaggtcg tcaacgggtt cgaccatcag atgcacatcg
    39961 atcggcacgc ttgcataagg cttcaacgct gcgcaaacca tagggccgaa ggtcaggttc
    40021 ggcacataat ggttgtccat cacgtcaaaa tggatcagat ctgcacctgc cgcaatgacg
    40081 ctttccacct cttcgccaag ccgtgcaaaa tctgccgata aaatgctggg tgcgatacgg
    40141 taagtagtca tgtttttttc cttcaatatc
//
LOCUS       DAXIDM010000006        39872 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000006 DAXIDM010000000
VERSION     DAXIDM010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 39872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39872
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.006"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            294..938
                     /gene="rplC"
                     /locus_tag="ACFOAE_000224"
     CDS             294..938
                     /gene="rplC"
                     /locus_tag="ACFOAE_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFC6883797.1"
                     /translation="MTLGLVGRKVGMTRVFDEQGVSVPVTVLDMSANRVTQVKSKDTD
                     GYTAVQVTFGQKKANRVNKAEAGHFAKAGVEAGRGLIEFALTEEKLAELKAGDEITVS
                     MFEVGQLVDVTGTSKGKGFSGTIKRHNFGAQRTSHGNSRSHRVPGSIGMAQDPGRVFP
                     GKRMAGQYGNTKATVQKLEVVRVDAERQLLLVKGAVPGAVNSDVVVRPSVKVGA"
     gene            938..1558
                     /gene="rplD"
                     /locus_tag="ACFOAE_000225"
     CDS             938..1558
                     /gene="rplD"
                     /locus_tag="ACFOAE_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFC6883798.1"
                     /translation="MELKVIDAKGQVSGSLSVSDALFAREYNEALVHQLVNAYLANAR
                     SGNRAQKTRAEVKHSTKKPWRQKGTGRARSGMTSSPLWRKGGRAFPNKPDENFTQKVN
                     RKMYRAGMATILSQLTRDERLFAIEALTAETPKTKVFAEQVKNLGLEQVLFVTKQLDE
                     NVYLASRNLPNVLVLEAQQVDPYSLLRYKKVIITKDAVAQLEEQWV"
     gene            1555..1869
                     /gene="rplW"
                     /locus_tag="ACFOAE_000226"
     CDS             1555..1869
                     /gene="rplW"
                     /locus_tag="ACFOAE_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFC6883799.1"
                     /translation="MNQQRLTQVILAPIVSEKSNVLAEKRNQMTFKVLANATKPEIKA
                     AVELLFGVQVASVTTVTTKGKTKRFGRTLGRRSDVKKAYVSLAAGQELDLEAAAAAAD
                     KE"
     gene            1875..2708
                     /gene="rplB"
                     /locus_tag="ACFOAE_000227"
     CDS             1875..2708
                     /gene="rplB"
                     /locus_tag="ACFOAE_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFC6883800.1"
                     /translation="MAIVKMKPTSAGRRGMVRVVTEGLHKGAPYAPLLEKKNSTAGRN
                     SNGHITTRHKGGGHKHHYRVVDFKRNKDGIPAKVERIEYDPNRTAFIALLCYADGERR
                     YIIAPRGIQVGAVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGA
                     SAVLLAKEGAYAQVRLRSGEVRKINVNCRATIGEVGNEEQSLKKIGKAGANRWRGIRP
                     TVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNK
                     G"
     gene            2715..2993
                     /gene="rpsS"
                     /locus_tag="ACFOAE_000228"
     CDS             2715..2993
                     /gene="rpsS"
                     /locus_tag="ACFOAE_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFC6883801.1"
                     /translation="MARSLKKGPYVDLHLLKKVDAARASNDKRPIKTWSRRSTILPDF
                     IGLTIAVHNGRTHVPVFISDNMVGHKLGEFSLTRTFKGHLADKKAKKK"
     gene            3002..3331
                     /gene="rplV"
                     /locus_tag="ACFOAE_000229"
     CDS             3002..3331
                     /gene="rplV"
                     /locus_tag="ACFOAE_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003795898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFC6883802.1"
                     /translation="MRVNAQHKNARISAQKARLVADLIRGKDVAQALNILAFSPKKGA
                     ELIKKVLESAIANAEHNNGADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCH
                     INVTVGN"
     gene            3341..4033
                     /gene="rpsC"
                     /locus_tag="ACFOAE_000230"
     CDS             3341..4033
                     /gene="rpsC"
                     /locus_tag="ACFOAE_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFC6883803.1"
                     /translation="MGQKINPTGFRLAVTKDWASKWFAKSTDFSTVLKQDIDVRNYLR
                     QKLANASVGRVVIERPAKSARITIHSARPGVVIGKKGEDIEVLKRDLQVLMGVPVHVN
                     IEEIRRPELDAQIIADGIAQQLEKRVQFRRAMKRAMQNAMRSGAKGIKIMTSGRLNGA
                     DIARSEWYREGRVPLHTLRANVDYATSEAHTTYGVLGLKVWVYTEGNIKSSKPEHESK
                     QRKAGRRNAAAN"
     gene            4017..4433
                     /gene="rplP"
                     /locus_tag="ACFOAE_000231"
     CDS             4017..4433
                     /gene="rplP"
                     /locus_tag="ACFOAE_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFC6883804.1"
                     /translation="MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTA
                     RQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKV
                     LYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ"
     gene            4433..4624
                     /gene="rpmC"
                     /locus_tag="ACFOAE_000232"
     CDS             4433..4624
                     /gene="rpmC"
                     /locus_tag="ACFOAE_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009175233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFC6883805.1"
                     /translation="MKANELKDKSVEQLNADLLDLLKAQFGLRMQNATGQLGKPSELK
                     RVRRDIARIKTVLTEKGAK"
     gene            4624..4887
                     /gene="rpsQ"
                     /locus_tag="ACFOAE_000233"
     CDS             4624..4887
                     /gene="rpsQ"
                     /locus_tag="ACFOAE_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFC6883806.1"
                     /translation="MSETKNVRTLQGKVVSDKMDKTVTVLVERKVKHPLYGKIIRLST
                     KIHAHDENNQYGIGDVVVISESRPLSKTKSWVVSELVEKARSI"
     gene            5109..5477
                     /gene="rplN"
                     /locus_tag="ACFOAE_000234"
     CDS             5109..5477
                     /gene="rplN"
                     /locus_tag="ACFOAE_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012728338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFC6883807.1"
                     /translation="MIQMQTILDVADNSGARRVMCIKVLGGSKRRYASVGDIIKVAVK
                     DAAPRGRVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLNNKLEPLGTRIFGPV
                     TRELRTERFMKIVSLAPEVL"
     gene            5489..5812
                     /gene="rplX"
                     /locus_tag="ACFOAE_000235"
     CDS             5489..5812
                     /gene="rplX"
                     /locus_tag="ACFOAE_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFC6883808.1"
                     /translation="MNKIIKGDRVVVIAGKDKGKQGQVVRVLGDKVVVEGVNVVKRHQ
                     KPNPMRGIEGGIITKEMPLDISNIAILNPETNKADRVGIKLIENEGKVKRVRFFKSNG
                     SIIGA"
     gene            5822..6361
                     /gene="rplE"
                     /locus_tag="ACFOAE_000236"
     CDS             5822..6361
                     /gene="rplE"
                     /locus_tag="ACFOAE_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFC6883809.1"
                     /translation="MARLREFYKETVVPELVKQFGYKSVMEVPRIEKITLNMGVGEAV
                     ADKKVMEHAVSDLEKIAGQKPVVTVARKSIAGFKIRDNYPVGCKVTLRRDQMFEFLDR
                     LITIALPRVRDFRGVSGKSFDGRGNYNMGVREQIIFPEIEYDKIDALRGLNITITTTA
                     KTDEEAKALLSLFKFPFKG"
     gene            6364..6669
                     /gene="rpsN"
                     /locus_tag="ACFOAE_000237"
     CDS             6364..6669
                     /gene="rpsN"
                     /locus_tag="ACFOAE_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFC6883810.1"
                     /translation="MAKKALINRDLKRQALAKKYAAKRAAIKAVINDSNATEEERFEA
                     RLRFQSIPRNAAPVRQRRRCALTGRPRGTFRKFGLGRIKIREIAMRGEIPGVVKASW"
     gene            6685..7077
                     /gene="rpsH"
                     /locus_tag="ACFOAE_000238"
     CDS             6685..7077
                     /gene="rpsH"
                     /locus_tag="ACFOAE_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFC6883811.1"
                     /translation="MSMHDPISDMLTRIRNAQRANKAAVAMPSSKLKCAIAKVLKEEG
                     YIEDFAVSSDVKSILEIQLKYYAGRPVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIA
                     IVSTSKGVMTDRKARSQGVGGELLCIVA"
     gene            7091..7624
                     /gene="rplF"
                     /locus_tag="ACFOAE_000239"
     CDS             7091..7624
                     /gene="rplF"
                     /locus_tag="ACFOAE_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFC6883812.1"
                     /translation="MSRVAKNPVTVPAGVEVKFGTEALVIKGKNGELSVPLHSDVAIE
                     FNDGKLTFVANNSSKQANAMSGTARALVSNMVKGVSEGFEKRLQLIGVGYRAQAQGKI
                     LNLSLGFSHPIVYEMPEGVSVQTPSQTEIVLTGSDKQVVGQVAAEIRAFRAPEPYKGK
                     GVRYVGEVVVMKEAKKK"
     gene            7638..7991
                     /gene="rplR"
                     /locus_tag="ACFOAE_000240"
     CDS             7638..7991
                     /gene="rplR"
                     /locus_tag="ACFOAE_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFC6883813.1"
                     /translation="MDKHTTRLRRARKTRARIADLKMVRLCVFRSNNHIYAQVISAEG
                     DKVLAQASTLEAEVRGSLKSGSNVEAAAIVGKRIAEKAKAAGVEKVAFDRSGFQYHGR
                     VKALAEAARENGLSF"
     gene            8010..8528
                     /gene="rpsE"
                     /locus_tag="ACFOAE_000241"
     CDS             8010..8528
                     /gene="rpsE"
                     /locus_tag="ACFOAE_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFC6883814.1"
                     /translation="MAKHEIEERGDGLIEKMVAVNRVTKVVKGGRIMAFSALTVVGDG
                     DGRIGMGKGKSKEVPVAVQKAMDQARRSMIKVPLKNGTIHHEVIGRHGATKVFMQPAK
                     EGSGVKAGGPMRLVFDAMGIHNISAKVHGSTNPYNIVRATLDGLSKLHTPADIAAKRG
                     LTVEDILGVNHG"
     gene            8521..8706
                     /gene="rpmD"
                     /locus_tag="ACFOAE_000242"
     CDS             8521..8706
                     /gene="rpmD"
                     /locus_tag="ACFOAE_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFC6883815.1"
                     /translation="MAEQKKIRVTLVKSLIGTIESHRACARGLGLRRREHTVEVLDTP
                     ENRGMINKISYLLKVES"
     gene            8708..9142
                     /gene="rplO"
                     /locus_tag="ACFOAE_000243"
     CDS             8708..9142
                     /gene="rplO"
                     /locus_tag="ACFOAE_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFC6883816.1"
                     /translation="MFLNTIQPAVGATHAGRRVGRGIGSGLGKTGGRGHKGQKSRSGG
                     FHKVGFEGGQMPLQRRLPKRGFKSLTASANAQLRLSELESIAVNEIDILVLKQAGLIA
                     STVSNVKVIASGEISKAVALKGIKVTKGARAAIEAVGGKIEM"
     gene            9154..10464
                     /gene="secY"
                     /locus_tag="ACFOAE_000244"
     CDS             9154..10464
                     /gene="secY"
                     /locus_tag="ACFOAE_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFC6883817.1"
                     /translation="MANQQTSSGSSKFGDLKKRLLFLFGALIVFRIGAHIPVPGVDAV
                     ALAKLYESAGNGILGILNMFSGGSLERFSIFAIGIMPYISASIIVQLASEILPSLKAL
                     KKEGEAGRKVITKYTRYGTVLLAILQSLGVASFVFQQGIVVTSSFEFHVSTVVSLVTG
                     TMFLMWLGEQITERGIGNGISLIITAGIASGIPSGIAKLVTLTNQGSMSMLTALFIVF
                     GALLLIYLVVYFESAQRKIPIHYAKRQFNGRAGSQNTHMPFKLNMAGVIPPIFASSII
                     LFPSTLLGWFGSADTNSVLHKIAGLLQHGQLLYMALFAATVIFFCYFYTALVFSPKEM
                     AENLKKSGAFVPGIRPGEQTSRYLEKVVLRLTLFGALYITTICLIPEFLTTVLNVPFY
                     LGGTSLLILVVVTMDFSTQINSYRLTQQYDKLMTRSEMKSFSRK"
     gene            10469..10687
                     /gene="infA"
                     /locus_tag="ACFOAE_000245"
     CDS             10469..10687
                     /gene="infA"
                     /locus_tag="ACFOAE_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFC6883818.1"
                     /translation="MAKEDTIQMQGEILETLPNATFKVKLENDHIVLGHISGKMRMHY
                     IRISPGDKVTVELTPYDLTRARIVFRAR"
     gene            10708..10821
                     /gene="rpmJ"
                     /locus_tag="ACFOAE_000246"
     CDS             10708..10821
                     /gene="rpmJ"
                     /locus_tag="ACFOAE_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006232360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFC6883819.1"
                     /translation="MRVQPSVKKICRNCKIIRRNRVVRVICTDLRHKQRQG"
     gene            10887..11249
                     /gene="rpsM"
                     /locus_tag="ACFOAE_000247"
     CDS             10887..11249
                     /gene="rpsM"
                     /locus_tag="ACFOAE_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFC6883820.1"
                     /translation="MARIAGVNIPNNAHIVIGLQAIYGIGATRAKLICEAANIAPDTK
                     AKDLDETQLDALRDQVAKYEVEGDLRREVTMSIKRLMDMGCYRGFRHRRGLPCRGQRT
                     RTNARTRKGPRKAIAGKK"
     gene            11269..11664
                     /gene="rpsK"
                     /locus_tag="ACFOAE_000248"
     CDS             11269..11664
                     /gene="rpsK"
                     /locus_tag="ACFOAE_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFC6883821.1"
                     /translation="MAKANTASRVRKKVRKTVSEGIVHVHASFNNTIITITDRQGNAL
                     SWATSGGAGFKGSRKSTPFAAQVAAEAAGKVAQEYGVKNLEVRIKGPGPGRESSVRAL
                     NALGFKITSITDVTPLPHNGCRPPKKRRI"
     gene            11684..12304
                     /gene="rpsD"
                     /locus_tag="ACFOAE_000249"
     CDS             11684..12304
                     /gene="rpsD"
                     /locus_tag="ACFOAE_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFC6883822.1"
                     /translation="MARYIGPKCKLARREGTDLFLKSARRSLDSKCKIDSAPGQHGAK
                     KPRLSDYGLQLREKQKIRRIYGVLERQFRRYFAEADRRKGSTGELLLQLLESRLDNVV
                     YRMGFGSTRAEARQLVSHKAIVVNGQVVNIPSFQVKAGDVVSVREKAKKQVRIQEALG
                     LATQIGLPGWVSVDADKLEGVFKNMPDRSELTGDINEQLVVEFYSK"
     gene            12330..13316
                     /gene="rpoA"
                     /locus_tag="ACFOAE_000250"
     CDS             12330..13316
                     /gene="rpoA"
                     /locus_tag="ACFOAE_000250"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFC6883823.1"
                     /translation="MQNSTTEFLKPRQIDVNTFSATRAKVSMQPFERGFGHTLGNALR
                     RILLSSMNGFAPTEVAIAGVLHEYSTVDGIQEDVVDILLNIKGIVFKLHGRSQVQLVL
                     KKSGSGVVSAGDIELPHDVEILNPGHVICHLADNGQIEMEIKVEQGRGYQSVSGRQVV
                     RDENRQIGAIQLDASFSPISRVSFEVEPARVEQRTDLDKLVLDIETDGSIDPEEAVRS
                     AARILIDQMSIFADLQGTPVEEVEEKAPPIDPVLLRPVDDLELTVRSANCLKAEDIYY
                     IGDLIQRTETELLKTPNLGRKSLNEIKEVLASKGLTLGSKLEAWPPVGLEKP"
     gene            13340..13708
                     /gene="rplQ"
                     /locus_tag="ACFOAE_000251"
     CDS             13340..13708
                     /gene="rplQ"
                     /locus_tag="ACFOAE_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFC6883824.1"
                     /translation="MRHRNGNRKLNRTSSHRAAMLRNMANSLLTHETIVTTLPKAKEL
                     RRVVEPLITLGKKPSLANRRLAFDRTRDRDVVVKLFGDLGPRFTARNGGYVRVLKYGF
                     RKGDNAPLALVELVDKPAAE"
     gene            13855..14568
                     /gene="minC"
                     /locus_tag="ACFOAE_000252"
     CDS             13855..14568
                     /gene="minC"
                     /locus_tag="ACFOAE_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004857 - enzyme inhibitor activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA];
                     GO_process: GO:1901891 - regulation of cell septum
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HFC6883825.1"
                     /translation="MMVYIMNAFDIKSTKMDVLSISLHTSDLFDLEDVLVKLGKKFQE
                     SGVVPFVLDVQEFDYPESLDLAALVSLFSRHGMQILGLKHSNERWAAAAMKYHLLFCL
                     SHSENVKELGQVEVQNTEDGQKARKTVLITSPVRTGQQVYAEDGDLIVTGAVSQGAEL
                     IADGNMHIYAPMRGRALAGAKGDTSARIFIHSMQAELVSVAGIYRNFEQDLPDHLHKQ
                     PVQILLQDNRLVISAIGSE"
     gene            14597..15412
                     /gene="minD"
                     /locus_tag="ACFOAE_000253"
     CDS             14597..15412
                     /gene="minD"
                     /locus_tag="ACFOAE_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0000918 - division septum site selection
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HFC6883826.1"
                     /translation="MAKIIVVTSGKGGVGKTTTSASIATGLALRGYKTAVIDFDVGLR
                     NLDLIMGCERRVVYDLINVIQGEATLNQALIKDKNCENLFILPASQTRDKDALTREGV
                     EKVMQELSGKKMGFEYIICDSPAGIEQGALMALYFADEAIVTTNPEVSSVRDSDRILG
                     ILQSKSHKAEQGGSVKEHLLITRYSPERVAKGEMLSVQDICDILHIPLLGVIPESQNV
                     LQASNSGEPVIHQDSVAASEAYKDVIARLLGENREMRFLEAEKKSFFKRLFGG"
     gene            15416..15679
                     /gene="minE"
                     /locus_tag="ACFOAE_000254"
     CDS             15416..15679
                     /gene="minE"
                     /locus_tag="ACFOAE_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HFC6883827.1"
                     /translation="MSLIEFLFGRKQKTATVARDRLQIIIAQERAQEGQAPDYLPTLR
                     KELMEVLSKYVNVSLDNIRISQEKQDGMDVLELNITLPEQKKV"
     gene            15683..16603
                     /gene="oxyR"
                     /locus_tag="ACFOAE_000255"
     CDS             15683..16603
                     /gene="oxyR"
                     /locus_tag="ACFOAE_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator OxyR"
                     /protein_id="HFC6883828.1"
                     /translation="MTLTELRYIVAVAQERHFGRAARRCFVSQPTLSIAIKKLEEELA
                     VSLFDRSSNDIITTEAGERIVAQARKVLEEAELIRHLANEEQNELEGAFKLGLIFTVA
                     PYLLPKLIVSLRRTAPKMPLMLEENYTHTLTESLKRGDVDAIIVAEPFQEPGIVTEPL
                     YDEPFFVIVPKGHSFEELDAVSPRMLGEEQVLLLTEGNCMRDQVLSSCSELAAKQRIQ
                     GLTNTLQGSSINTIRHMVASGLAISVLPATALTENDHMLFSIIPFEGTPPSRRVVLAY
                     RRNFVRPKALSAMKAAIMQSQLHGVSFIRD"
     gene            complement(16600..16833)
                     /locus_tag="ACFOAE_000256"
     CDS             complement(16600..16833)
                     /locus_tag="ACFOAE_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883829.1"
                     /translation="MAIVRQGEATPYWFLLIHYTWHCIGTDENIHSDAKVEYLQDGSF
                     RGDAILKIDDDGNILAYRVVGSGKWRFENNACA"
     gene            17177..17566
                     /locus_tag="ACFOAE_000257"
     CDS             17177..17566
                     /locus_tag="ACFOAE_000257"
                     /inference="COORDINATES: protein motif:HMM:NF017109.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6883830.1"
                     /translation="MRYTIKTFQTLADETFPSKNFKILSFNGVARPITIVCPTHGVQT
                     VSAGQAFIRSKHGCPACGLVLSTSVLASRGRSVSILDTATGETLSFPSVQAAAKALNT
                     SYGSIRTKLDGRSSPDNLVCNRYKVMP"
     gene            complement(17937..20774)
                     /locus_tag="ACFOAE_000258"
     CDS             complement(17937..20774)
                     /locus_tag="ACFOAE_000258"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFC6883831.1"
                     /translation="MLDKYSPAEIESKHYQNWEEQGYFQPDMDLTKPSFSIQLPPPNV
                     TGTLHMGHAFNQTIMDGLTRYYRMKGCNTAWIPGTDHAGIATQIVVERQLAAQNVSRH
                     DLGREKFLEKVWEWKEVSGGTITQQMRRVGCSADWTREYFTMDDVRAETVTEVFVRLY
                     EQGLIYRGKRLVNWDPVLGTAVSDLEVESVEEQGSMWHIRYPLADNPAEAVIVATTRP
                     ETLLGDVAVAVNPEDERYTHLIGKELILPLTGRTIPVIADEYVEKDFGTGCVKITPAH
                     DFNDYEVGKRHDTRLVNVFDLEAKVLANAEVFNFKGEAQPSFALPEKYAGLDRFAARK
                     QMVADLQEQGFLVEIKAHTLMTPKGDRTGSVIEPMLTSQWFVAMSATPNGGEPDSEFK
                     GLSLADKAKKAVDSGAVRFIPENWVNTYNQWMNNIQDWCISRQLWWGHQIPAWYDNEG
                     NVYVARNQEEAEKQAGKTGLTREEDVLDTWFSSALVPFSTLGWPSETDELKAFLPSNV
                     LVTGYEIIFFWVARMIMMTTHFTGKVPFKDVYIHGIVRDHEGKKMSKSEGNVIDPVDL
                     IDGIDLDKLLVKRTTGLRKPETAPKVEEATKKLFPEGIPSMGADALRFTMASYASLGR
                     SVNFDFKRAEGYRNFCNKIWNATNFVLMNTENQDCGYGATATEPRGYSFPDMWIVGRL
                     NQTIEQVTQAYETYRFDLAAETLYSFVWNDYCDWYLELAKVQLQTGCASRQRATRHTL
                     LRVLEAALRLLHPIIPFITEELWQTVAPMCDAKTADSIMLARFPEADGGEIVQTAFEQ
                     MTVLQDLIGAVRNLRGEMGIQPNVKAPLFVESADDLADYLKYLPMMTRLTEARQVAAL
                     PESEDAPVAVCNGARLMLKVEIDKAAETARLSKEAEKLQKALDKLNAKLSKPGYTEKA
                     PAHLVEKDKADLAELEDKMAKVQTQLSKLKD"
     gene            complement(20871..21680)
                     /gene="zupT"
                     /locus_tag="ACFOAE_000259"
     CDS             complement(20871..21680)
                     /gene="zupT"
                     /locus_tag="ACFOAE_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HFC6883832.1"
                     /translation="MPDFSMSNLAVAFSITLAAGLFTVLGSGLVMFSKTPNPRVLSFG
                     LAFAGGAMVYVSLTEIFSKSSEAFAEIYDKDHAFAAATMAFLAGMGGIALIDRLVPNP
                     HETLDAQDPSFQESKRRHIARVGMMAAFAITAHNFPEGLATFFATLENPAVGMPLALA
                     IAIHNIPEGISIAAPVYFATRSRKKTVWACLLSGLAEPLGAALGYLVLQPFLSPAVFG
                     SVFGVIAGVMVFLALDELLPAAKRYSDGHETVYGLTMGMAVIAVSLVLFHF"
     gene            complement(21861..23117)
                     /locus_tag="ACFOAE_000260"
     CDS             complement(21861..23117)
                     /locus_tag="ACFOAE_000260"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008718 - D-amino-acid dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0055130 - D-alanine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HFC6883833.1"
                     /translation="MKVLVLGAGVAGVSSAWYLAEAGHEVTVIDRAKGVAMETSFANA
                     GQLSYGYTTPWAAPGIPTKALKWLFKSHPPLLFRPDGSLYQIEWLWRMLQNCTAAHYQ
                     TNKERMVRISEYSREMFRRFEAQTGMNFEERKKGTLQIFRQTKEVEAAEQDIAVLERY
                     GVPYRRLKPEECAEFEPALARVTAKIAGGLHLPADATGDCHLFTENLYKLCQEKGVQF
                     HFNQTISRIDHNGLRIKAVETETGRFEADAVVCALGCFSRTVLAQLDLDLPIYPVKGY
                     SLTLPVTNSDGAPVSTVLDESYKVAITRFDNRIRVGGMAELSGYEIKLPEKRRETLAL
                     VVNDLFPEGGDLSQALFWSGLRPMTPDSTPLIGRTRFENLFLNTGHGTLGWTMSLGSA
                     KLTADIVSGKDTEIRSDDLSLSRYQA"
     gene            complement(23196..24587)
                     /locus_tag="ACFOAE_000261"
     CDS             complement(23196..24587)
                     /locus_tag="ACFOAE_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC6883834.1"
                     /translation="MQVFLDNPKAFFETVSGWVWGPLMLMLLVGTGILLTVLLKGLQF
                     TMLGYALKQAFMPPKKHKSGEGHEGDISHFAALMTALSATIGTGNIAGVATAVVTGGP
                     GAVFWMWMTAIFGMATKYGEGVLAVKYRVNNSKGEMSGGPMYYIEKGLGKNWKWMAVA
                     FALFGTFASFGIGSSVQSNSVAQAVQTSFGIEPAYTGITLTVLTAVVVLGGIKGIAKA
                     ASFIVPAMAVFYVLGGLSIIAINSDALMPAVKLIFSDAFSAQAVAGGAIGTVIRYGVA
                     RGVFSNEAGMGSAPIAAAAAKTDHPVRQALVSMTGTFLDTIVVCSITGIVLVMGLLGA
                     GGEFVKPEVSGAALTTVTFQKMLPGIGGWIVTIGLIFFAYSTILGWCYYGEKCAVYVF
                     GEKFAGLYRVGYVSSVMLGTVLSLDLVWLASDTFNGLMALPNLIALLLMAKVIVNETR
                     DFKQKITNGELPH"
     gene            complement(24944..25720)
                     /gene="lpxA"
                     /locus_tag="ACFOAE_000262"
     CDS             complement(24944..25720)
                     /gene="lpxA"
                     /locus_tag="ACFOAE_000262"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008780 -
                     acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine
                     O-acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HFC6883835.1"
                     /translation="MTLIHPTAVIDPKAELDSSVKVGAYTVIGPNVQIGANTEIGPHA
                     VINGHTSIGENNRIFQFASLGEIPQDKKYRDEPTKLIIGNGNTIREFTTFNLGTVTGI
                     GETRIGDDNWIMAYCHLAHDCVVGNHTIFANNASLAGHVTVGDYVVLGGYTLVFQFCR
                     IGDYAMTAFAAGVHKDVPPYFMASGYRAEPAGLNSEGMRRNGFTAEQISAVKNVYKTL
                     YHRGIPFEEAKADILRRAETQAELAVFRDFFAQSTRGIIR"
     gene            complement(25763..26443)
                     /locus_tag="ACFOAE_000263"
     CDS             complement(25763..26443)
                     /locus_tag="ACFOAE_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HFC6883836.1"
                     /translation="MERYKNAVGEDKAAELYLLNLSLSRELFHVVSIFEIVLRNKIDI
                     CLQQAFKDRNWLYNSIQPQTNPALKYQGCFLRNGTKESAELIKVALSKIQNNSGGKFD
                     HNQLVAGLGFGFWRYLFAGGKDAQFDATGKVLMKVFPKKPKSTPSVQYNQKWIFRELS
                     NINKFRNRLAHHEPICFKGAIKDTNYARNIHQSIFELLNYMDVDTASVFSHFSDQVIA
                     VCDEIDKL"
     gene            complement(26650..27099)
                     /gene="fabZ"
                     /locus_tag="ACFOAE_000264"
     CDS             complement(26650..27099)
                     /gene="fabZ"
                     /locus_tag="ACFOAE_000264"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFC6883837.1"
                     /translation="MDVQLPIEAKDIQKLIPHRYPFLQLDRITAFESMKTLTAIKNVT
                     INEPQFQGHFPDLPVMPGVLIIEAMAQACGTLAILSEGGRKENEFFFFAGIDEARFKR
                     QVIPGDQLVFEVELLTSRRGIGKFNAVAKVDGQVAVEAIIMCAKRVV"
     gene            complement(27135..28178)
                     /gene="lpxD"
                     /locus_tag="ACFOAE_000265"
     CDS             complement(27135..28178)
                     /gene="lpxD"
                     /locus_tag="ACFOAE_000265"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HFC6883838.1"
                     /translation="MIPATYTLSQITARLGGEWRGEDISVTTVRPLADAQAEHISFLA
                     NPKYKAEVHDSSAGAVIVSAKAADGFEGRNLIVADDPYLYFAKVARLFSPVVKAHGGI
                     HPTAVVEPGATVPASCEIGANAYIGANTVLGEGCRILANAVVQHDCKLGDEVVMHPNA
                     VVYYGCTLGRRVEIHSGAVIGADGFGLAFAGDSWFKIPQTGAVTLGDDVEIGSNTNID
                     RGAMSDTTVGNGTKIDNQVQIGHNCKIGSHTVIAAKTGISGSVTIGSYCIIGGGVGTV
                     GHIEIADKTTIGGGTSVTHSITESGKHLAGIFPMSTHKEWARNAVYIHRLSEMNKRLK
                     TLEQQLSDGKDTQ"
     gene            complement(28211..28711)
                     /locus_tag="ACFOAE_000266"
     CDS             complement(28211..28711)
                     /locus_tag="ACFOAE_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpH family outer membrane protein"
                     /protein_id="HFC6883839.1"
                     /translation="MTRLTRAFAAALIGLCCTAGAHADTFQKIGFINTERIYLESKQA
                     RKIQKTLDSEFSARQDELQKLQREGLDLERQLAEGKLRNAKKAQAEEKWRGLVAAFRK
                     KQAQFEEDYNLRRNEEFASLQQNANRVIVKIAKQEGYDVILQNVIYVNTQYDVTDSVI
                     KEMNAR"
     gene            complement(28777..31170)
                     /gene="bamA"
                     /locus_tag="ACFOAE_000267"
     CDS             complement(28777..31170)
                     /gene="bamA"
                     /locus_tag="ACFOAE_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA];
                     GO_process: GO:0071709 - membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HFC6883840.1"
                     /translation="MKLKQIASALMVLGISPLALADFTIQDIRVEGLQRTEPSTVFNY
                     LPVKVGDTYNDTHGSTIIKSLYATGFFDDVRVETADGQLLLTVIERPTIGSLNITGAK
                     MLQNDAIKKNLESFGLAQSQYFNQATLNQAVAGLKEEYLGRGKLNIQITPKVTKLARN
                     RVDIDITIDEGKSAKITDIEFEGNQVYSDRKLMRQMSLTEGGIWTWLTRSNQFNEQKF
                     AQDMEKVTDFYQNNGYFDFRILDTDIQTNEDKTKQTIKITVHEGGRFRWGKVSIEGDT
                     NEVPKAELEKLLTMKPGKWYERQQMTAVLGEIQNRMGSAGYAYSEISVQPLPNAETKT
                     VDFVLHIEPGRKIYVNEIHITGNNKTRDEVVRRELRQMESAPYDTSKLQRSKERVELL
                     GYFDNVQFDAVPLAGTPDKVDLNMSLTERSTGSLDLSAGWVQDTGLVMSAGVSQDNLF
                     GTGKSAALRASRSKTTLNGSLSFTDPYFTADGVSLGYDVYGKAFDPRKASTSIKQYKT
                     TTAGAGIRMSVPVTEYDRVNFGLVAEHLTVNTYNKAPKHYADFIKQYGKTDGTDGSFK
                     GWLYKGTVGWGRNKTDSALWPTRGYLTGVNAEIALPGSKLQYYSATHNQTWFFPLSKT
                     FTLMLGGEIGYANGYGKTKEIPFFENFYGGGLGSVRGYESGTLGPKVYDEYGEKISYG
                     GNKKANVSAELLFPMPGAKDARTVRLSLFADAGSVWDGKTYDDNSSSATGGRVQNIYG
                     AGNTHKSTFTNELRYSAGGAVTWLSPLGPMKFSYAYPLKKKPEDEIQRFQFQLGTTF"
     gene            complement(31227..32567)
                     /gene="rseP"
                     /locus_tag="ACFOAE_000268"
     CDS             complement(31227..32567)
                     /gene="rseP"
                     /locus_tag="ACFOAE_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFC6883841.1"
                     /translation="MHTLLAFIFAILILVSLHEFGHYIVARLCGVKVVRFSVGFGKPF
                     FTRKRGDTEWCLAPIPLGGYVKMVDTREGEVSEADLPYAFDKQHPAKRIAIVAAGPLT
                     NLALAVLLYGLSFSFGVTELRPYVGTVEPDTIAARAGFQSGDKIQSVNGTPVADWGSA
                     QTEIVLNLEAGKVAVGVQTASGAQTVRTIDAAGTPEAGKIAKNQGYIGLMPFKITTVA
                     GGVEKGSPAEKAGLKPGDRLTAADGKPITSWQEWANLTRQSPGRKIALTYERAGQTHT
                     ADIRPDTVEQPDHTLIGRVGLRPQPDRAWDAQIRRSYRPSVIRAFGMGWEKTVSHSWT
                     TLKFFGKLISGNASVSHISGPLTIADIAGQSAELGLQSYLEFLALVSISLGVLNLLPV
                     PVLDGGHLVFYTAEWIRGKPLGERVQNIGLRFGLALMMLMMAVAFFNDVTRLLG"
     gene            complement(32602..33837)
                     /gene="ispC"
                     /locus_tag="ACFOAE_000269"
     CDS             complement(32602..33837)
                     /gene="ispC"
                     /locus_tag="ACFOAE_000269"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0030604 - 1-deoxy-D-xylulose-5-phosphate
                     reductoisomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070402 - NADPH binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HFC6883842.1"
                     /translation="MPSENASDGIRYKVIPIMTPQVLTILGSTGSIGESTLDVVSRHP
                     EKFRVFALAGHKQVEKLAAQCQTFRPEYAVVADAEHAARLEALLKRDGTATQVLHGAQ
                     ALVDVASADEVSGVMCAIVGAVGLPSALAAAQKGKTIYLANKETLVVSGALFMETARA
                     NGAAVLPVDSEHNAVFQVLPRDYAGRLNEHGIASIILTASGGPFLTADLNTFDSITPD
                     QAVKHPNWRMGRKISVDSATMMNKGLELIEAHWLFNCPPDKLEVVIHPQSVIHSMVRY
                     RDGSVLAQLGNPDMRTPIAYCLGLPERIDSGVGDLDFDALSALTFQKPDFDRFPCLKL
                     AYEAMNAGGAAPCVLNAANEAAVAAFLDGQIKFTDIAKTVAHCLSQDFSDGIGDIGGL
                     LAQDARTRAQARAFIGTLR"
     gene            complement(33842..34639)
                     /locus_tag="ACFOAE_000270"
     CDS             complement(33842..34639)
                     /locus_tag="ACFOAE_000270"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFC6883843.1"
                     /translation="MLKQRVITAMWLLPLMLGMLFYAPQWLWAAFCGLIALIALWEYA
                     RMGGLCKIKTNHYLAATLVFGVVAYAGGWMLPNLVWYVVLAFWLAVMPLWLRFKWRLN
                     GGWQVYAVGWLLVMPFWFALVSLRPHPDDALPLLAVMGLVWVADICAYFSGKAFGKHK
                     IAPAISPGKSWEGAIGGAVCVAVYMTAVRSAGWLAFDTGWFDTVLIGLVLTVVSVCGD
                     LLESWLKRAAGIKDSSNLLPGHGGVFDRTDSLIAVISVYAAMMSVLN"
     gene            complement(34642..35388)
                     /locus_tag="ACFOAE_000271"
     CDS             complement(34642..35388)
                     /locus_tag="ACFOAE_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFC6883844.1"
                     /translation="MKSSTQAVLEHTAIPKHIAVIMDGNGRWAKKRFLPRIMGHKRGL
                     DALENMVKHCAKLGVQYLTVFAFSTENWRRPEDEVSFLMGLFLQALQKQVRRLHENNM
                     RLKILGSRERFSRQILKGIEEAEALTANNTGLTLSIAADYGGRWDILQAANKLIAEGV
                     SEITEDTLAKHLMLGNAPEPDLFIRTGGETRISNFLLWQMAYAELYFTDILWPDFDET
                     ALDAAVASFQKRERRFGRTSEQLPIEQQRN"
     gene            complement(35444..36001)
                     /gene="frr"
                     /locus_tag="ACFOAE_000272"
     CDS             complement(35444..36001)
                     /gene="frr"
                     /locus_tag="ACFOAE_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFC6883845.1"
                     /translation="MINDIQKTAEGKMQRSVEVLKENLAKVRTGRAHTGLLDQVEVEY
                     WGSMVPVSQVANVTLLDARTIGVKPFEGNMAAKVEKAIRDSNLGLNPAAVGDLIRVPM
                     PMLTEERRKDLIKVVRGEAEEGRVSIRNVRRDANDHIKKLLKDKEISEDEARRGEEAV
                     QKLTDKYITEADKLLTTKEEDLMAI"
     gene            complement(36181..37308)
                     /locus_tag="ACFOAE_000273"
     CDS             complement(36181..37308)
                     /locus_tag="ACFOAE_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFC6883846.1"
                     /translation="MNTSQRNRLSSRWLNSYERYRYRRLIHSVRLGGAVLFATALARL
                     FHLQHGEWIGMTVFVVLGMLQFQGAIYSKAVERMLGTVIGLGAGLGVLWLNQHYFHGN
                     LLFYLTVGTASALAGWAAVGKNGYVPMLAGLTMCMLIGDNGSEWFDSGLMRAMNVLIG
                     AAIAIAAAKLLPLKSTLMWRFMLADNLTDCSKMIAEISNGRRMTRERLEENMAKMRQI
                     NARMVKSRSHLAATSGESRISPAMMEAMQHAHRKIVNTTELLLTTAAKLQSPKLNGSE
                     IRLLDRHFTQLQTDLQQTVALINGRHARRIRIDTAINPELEALAEHLHYQWQGFLWLS
                     TNMRQEISALVILLQRTRRKWLNAHERQHLRQSLLETREHG"
     gene            complement(37382..37457)
                     /locus_tag="ACFOAE_000274"
     tRNA            complement(37382..37457)
                     /locus_tag="ACFOAE_000274"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37422..37424),aa:Thr,seq:cgt)
     gene            37562..38047
                     /locus_tag="ACFOAE_000275"
     CDS             37562..38047
                     /locus_tag="ACFOAE_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883847.1"
                     /translation="MYVNEKYPYAALFAGLVFLTLPFALSVHDALAFAFGRTGLLVSV
                     SDGGFGWRGGWDSTVWFVFGVFAFLNVVVSAGLTKLAYKKMMRRHSRYALFLSGVAAC
                     AAAAVAWIFELLLGSAALGGLRGEAVLEYAFAVWLVAMLTLPKRLTRAPVQLVVFHRK
                     K"
     gene            38143..38766
                     /gene="rsmG"
                     /locus_tag="ACFOAE_000276"
     CDS             38143..38766
                     /gene="rsmG"
                     /locus_tag="ACFOAE_000276"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFC6883848.1"
                     /translation="MERKERLQSGIAAMGLDISETAQDRLLAYVDLLKKWNKTYNLTA
                     LRDEEKMIVHHLLDSLTLLPYIEGAQTMLDVGSGGGQPGIPAAVCRPDVQITLLDANT
                     KKTAFLQQAVIELGLDNVRVVSGRVEAVSDVRADVITSRAFAELADFVSWTAHLLKDG
                     GYWAAMKGVYPQGEIDHLPQDVCVEKVQRLDVPGLDAERHIVILRKR"
     gene            38865..39638
                     /locus_tag="ACFOAE_000277"
     CDS             38865..39638
                     /locus_tag="ACFOAE_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFC6883849.1"
                     /translation="MSANILAIANQKGGVGKTTTTVNLAASLASRGKRVLVVDLDPQG
                     NATTGSGIDKAGLQSGVYQVLLGDADVKSATVRSKEGGYAVLGANRALAGAEIELVQE
                     IAREVRLKNALKAVAEDYDFILIDCPPSLTLLTLNGLVAAGGVIVPMLCEYYALEGIS
                     DLIATVRKIRQAVNPDLDITGIVRTMYDSRSRLVAEVSEQLRSHFGDLLFETAIPRNI
                     RLAEAPSHGMPVMAYDAQAKGTKAYLALADELMARVSGK"
BASE COUNT         9364 a         8984 c        10909 g        10615 t
ORIGIN      
        1 tttgacgaac tgagcatccc cgattacagt catcaaccat attccggttt gtcggagaaa
       61 gatgcatacg ctgtgatgac cggataccga ccctttaaaa gagtctgacc ctatgccgtc
      121 tgaaaattca aaacgcttca gacggcatat tgaagatatt tctgatattt ctgttgatat
      181 ttctttaact tgtcagatat aatgccgagc ttggtacatt tgtgccaagt ttaactttgt
      241 ctgaaagaca ggccaatcgt agcctgtccc tttactttaa aaggaaaata atcatgactt
      301 taggtctggt tggacgcaaa gttggtatga cccgcgtgtt cgacgaacag ggtgtttctg
      361 ttccggtaac cgttttggat atgtctgcca accgcgttac acaagtaaaa tccaaagata
      421 ctgacggcta tactgccgtt caagttacct ttggtcagaa aaaagccaat cgtgtcaaca
      481 aagccgaagc cgggcacttt gcaaaagcag gtgttgaagc cggtcgcggt ttgattgagt
      541 ttgctttgac tgaagaaaaa ctggctgaat tgaaagctgg tgacgaaatc accgtttcta
      601 tgtttgaagt cggtcaactg gtcgatgtaa ccggtacctc taaaggtaaa ggtttctccg
      661 gcacgattaa acgtcataac ttcggcgccc aacgtacttc ccacggtaac tcccgctctc
      721 accgcgttcc aggttctatc ggtatggcac aagacccggg tcgcgtgttc cccggtaagc
      781 gcatggccgg ccaatacggc aacaccaaag caactgttca aaaattggaa gttgtccgtg
      841 ttgatgcaga acgccaactg ctgttggtta agggtgctgt tccgggtgcg gtcaacagcg
      901 atgttgtagt tcgtcccagc gtgaaagtag gtgcgtaatg gaattgaaag taattgacgc
      961 taaaggacaa gtttcaggca gcctgtctgt ttctgatgct ttgttcgccc gcgaatacaa
     1021 tgaagcgttg gttcatcagc tggtaaatgc ctacttggca aacgcccgct ccggtaaccg
     1081 cgctcaaaaa acccgtgccg aagtaaaaca ctcaaccaaa aaaccatggc gtcaaaaagg
     1141 taccggccgt gcccgttccg gtatgacttc ttctccgctg tggcgtaaag gtggtcgcgc
     1201 gttcccgaac aaacccgacg aaaacttcac tcaaaaagta aaccgcaaaa tgtaccgtgc
     1261 cggtatggcg actattctgt cccaattgac tcgtgacgag cgtttgtttg cgattgaggc
     1321 gttgactgcc gaaactccta aaaccaaagt ttttgctgaa caagtgaaaa atctgggtct
     1381 agagcaagtg ttgtttgtaa ccaaacagct cgacgagaat gtttacttgg cttcacgcaa
     1441 cttgccaaac gtgttggttt tggaagctca acaagttgat ccttacagct tgctgcgtta
     1501 caaaaaagta atcatcacta aagatgcagt tgcacaatta gaggagcaat gggtatgaat
     1561 caacaacgtt tgactcaagt gattttggca cctatcgttt ctgaaaaaag caacgtattg
     1621 gctgaaaaac gcaaccaaat gacgtttaaa gttttggcaa atgcaaccaa acctgaaatc
     1681 aaagcggctg ttgagctgct gtttggtgtt caagttgctt ctgtaactac cgttacaact
     1741 aaaggcaaaa ctaagcgttt tggtcgtact ttgggccgcc gcagcgatgt taaaaaagct
     1801 tatgtaagct tggctgccgg tcaagagttg gatttggaag ccgctgctgc agctgcagat
     1861 aaggaataaa caaaatggca atcgttaaaa tgaagccgac ctctgcaggc cgtcgcggca
     1921 tggttcgcgt ggtaacagaa ggtttgcaca aaggtgcgcc ttatgcacct ttgctcgaaa
     1981 agaaaaattc tactgccggt cgtaacagta atggtcatat caccacccgt cacaaaggcg
     2041 gcggtcataa acaccattac cgtgttgtag actttaaacg taacaaagac ggcattcctg
     2101 ctaaggtaga gcgtatcgaa tacgatccta accgtactgc cttcatcgca ctgttgtgct
     2161 atgcagacgg cgagcgtcgt tacatcatcg ctcctcgcgg tattcaagtc ggtgccgtat
     2221 tggtttccgg tgctgaagct gccatcaaag taggcaacac cctgccgatc cgcaacattc
     2281 ccgttggtac gactatccac tgtatcgaaa tgaaacccgg taaaggtgct caaatcgcac
     2341 gttctgccgg tgcttctgcg gtattgctgg ctaaagaagg cgcgtacgct caagtccgtc
     2401 tgcgctctgg cgaagttcgt aaaatcaacg taaattgccg tgcgaccatc ggtgaagttg
     2461 gtaacgaaga gcaaagcctg aaaaaaatcg gtaaagccgg tgccaaccgt tggcgcggta
     2521 ttcgtccgac cgtacgcggt gttgtcatga atcctgtcga tcacccgcat ggtggtggtg
     2581 aaggccgtac gggcgaggcc cgcgaaccgg tcagcccatg gggtactcct gctaaaggct
     2641 accgcactcg taataacaaa cgcacggata acatgattgt tcgtcgccgt tactcaaata
     2701 aaggttaatt tagtatggct cgttcattga aaaaaggccc atatgtagac ctgcatttgc
     2761 tgaaaaaagt agatgctgct cgcgcaagca acgacaaacg cccgattaaa acctggtctc
     2821 gtcgttctac cattctgcct gattttatcg gtctgaccat tgctgtgcac aacggccgca
     2881 cccatgtgcc tgtgtttatc agcgacaata tggttggtca taaattaggc gaattctcat
     2941 tgacccgtac ctttaaaggc cacttggccg ataaaaaggc taaaaagaaa taaggtgaat
     3001 catgagagta aatgcacaac ataaaaatgc ccgtatctct gctcaaaagg ctcgtttggt
     3061 agctgatttg attcgtggta aagacgttgc ccaagctttg aatattttgg ctttcagtcc
     3121 taaaaaaggt gccgagctga ttaaaaaagt attggagtca gctattgcta atgccgagca
     3181 caataacggt gcggacattg atgaactgaa agtggtaact atctttgttg acaaaggccc
     3241 aagcttgaaa cgttttcaag ctcgcgccaa aggtcgcggt aaccgcatcg aaaaacaaac
     3301 ttgtcatatc aatgtgacag tgggtaacta aggaaaagct atgggacaaa agattaaccc
     3361 tacaggcttt cgcctggcgg taactaaaga ctgggcttca aaatggtttg ctaaaagcac
     3421 cgacttttct actgttttga agcaggatat cgatgttcgc aattatttgc gtcaaaaatt
     3481 ggccaatgct tcggttggtc gagtggttat tgaacgccct gcaaaatctg cacgcattac
     3541 cattcactcc gctcgtccgg gtgtggttat cggtaaaaaa ggtgaggata tcgaggtttt
     3601 gaaacgtgac ttgcaagtct tgatgggtgt acctgttcat gtaaatattg aagagattcg
     3661 ccgtcctgag ttggatgctc aaattattgc tgacggtatt gcccagcagt tggaaaagcg
     3721 cgttcaattc cgtcgtgcta tgaaacgagc aatgcaaaat gcaatgcgtt ctggtgctaa
     3781 aggcattaag attatgactt caggccgtct gaatggtgcg gatattgccc gtagcgaatg
     3841 gtatcgtgaa ggtcgcgtgc cactgcatac tttacgtgca aatgtagatt atgcaaccag
     3901 cgaagcgcac accacatatg gtgtattggg tctgaaagtt tgggtttata cggaaggcaa
     3961 tattaaatct tccaaacctg aacatgagag taaacaaaga aaggcaggta gacgtaatgc
     4021 tgcagccaac tagactgaaa taccgtaagc aacaaaaggg tcgcaatact ggcatcgcta
     4081 ctcgcggtaa taaggtaagt ttcggtgagt tcggcttgaa agccgtaggt cgtggtcgtt
     4141 tgactgcccg tcaaatcgaa gctgctcgtc gtgcaatgac ccgtcatatc aaacgtggtg
     4201 gtcgtatttg gattcgtgta ttccctgata aaccgattac tgaaaagcct attcaagttc
     4261 gtatgggtgg cggtaaaggt aacgtggaat attacattgc cgaaattaaa ccaggtaaag
     4321 tgttgtatga aatggatggc gttccagagg aactggctcg tgaagcattc gagttggctg
     4381 ctgccaaatt gcctattcct acaacctttg tagtaagaca ggtgggtcaa taatgaaagc
     4441 aaatgaattg aaagacaaat ccgttgagca gttgaatgca gatttgttgg acttgttgaa
     4501 agctcagttt ggcttacgta tgcaaaacgc taccggtcaa ttaggcaaac caagtgaatt
     4561 gaaacgtgta cgtcgcgata ttgctcgtat taaaaccgtt ttaactgaaa aaggtgctaa
     4621 gtaatgagcg aaactaaaaa tgttcgtact ttgcaaggca aagtagtaag cgacaaaatg
     4681 gataaaaccg taacagtatt ggttgagcgt aaagtaaaac atccgctgta tggtaagatt
     4741 attcggttat ctactaaaat ccatgcccat gatgaaaata atcaatatgg aattggtgat
     4801 gtggttgtta tatcggaatc ccgtccattg tcaaaaacta aatcttgggt tgtcagtgag
     4861 ctggttgaga aagcacgttc tatttaagaa ttaaagcaac gtgcttggaa tgggaaacga
     4921 agtattgcag caaatttaat ttgcgtgtaa acttcgtttc ctgtctttca gtttcttctg
     4981 gaagtttctt ccctttcggg gtccaagact ggtttacttg aaccgcaagg tttcatttaa
     5041 taagcagcgg ctttgctgta agttatctga aagtggtaaa ttaagttggt taatttaaag
     5101 gtaataacat gattcaaatg cagaccatct tagatgtggc tgataactct ggtgcgcgtc
     5161 gcgtaatgtg tatcaaggta ttgggcggat ctaagcgtcg ctacgcttct gttggcgata
     5221 ttattaaagt ggcagttaaa gatgcggctc cgcgtggccg tgtcaaaaaa ggcgatgtat
     5281 ataatgcggt agttgttcgt actgctaagg gtgtacgtcg tcctgatggt gcgttaatta
     5341 aattcgataa caatgccgcc gtgttactga ataataaact tgaacctttg ggtactcgta
     5401 tctttggtcc ggtaacccgt gaattgcgta ctgagcgatt tatgaaaatc gtttcattgg
     5461 cacctgaagt attataagga atggcacgat gaataaaatc attaaaggcg atagggttgt
     5521 agtaattgct ggtaaggata aaggtaagca gggtcaagta gttcgagtgt tgggtgataa
     5581 agttgttgtt gagggcgtta atgttgtaaa acgccatcaa aaacctaatc caatgcgtgg
     5641 cattgagggc ggtattatta ctaaagaaat gcctttggat atttctaata tcgcaatcct
     5701 gaatccggaa actaataaag cggaccgtgt tggtattaag ctgattgaaa atgaaggcaa
     5761 agttaaacgc gttcgtttct tcaaatcaaa tggctctatc attggggcat aaggagataa
     5821 catggctcgg ttgagagagt tttataaaga gacagttgtt cctgaattgg ttaaacaatt
     5881 tggttacaaa tcagtaatgg aagtcccgcg tattgaaaaa atcaccttga atatgggtgt
     5941 gggtgaggct gttgctgaca aaaaagttat ggaacatgct gtttccgatt tagagaaaat
     6001 tgccggtcaa aaaccggttg ttactgttgc ccgtaaatct atcgcaggtt ttaaaatccg
     6061 tgataactat ccggttggtt gcaaagtaac attgcgtcgt gatcaaatgt ttgaattctt
     6121 ggatcgtttg attactattg cattacctcg cgtacgtgac ttccgtggtg tgagcggtaa
     6181 atcatttgat ggccgtggca attacaatat gggtgttcgt gagcaaatta tttttccgga
     6241 aattgaatac gataaaattg atgctttgcg tggtttgaat attactatta ctactacagc
     6301 aaaaaccgat gaggaagcga aagctttatt gtcattgttt aaatttccgt tcaaaggata
     6361 atcatggcta agaaagcact tattaatcgt gatctgaaac gtcaagcttt ggctaaaaaa
     6421 tatgcggcta aacgcgcggc aattaaagcg gtaatcaatg attcgaatgc aactgaggaa
     6481 gagcgttttg aggctcgttt gaggtttcaa tccattcctc gtaatgcggc acctgtgcgt
     6541 caacgtcgtc gttgtgcttt gacaggtcgc cctcgtggta ctttccgtaa atttggtttg
     6601 ggtcgtatta aaatccgtga aatcgccatg cgtggcgaaa ttccgggtgt tgttaaagcc
     6661 agctggtaat aggagtaatt aagaatgagt atgcatgatc ctatttccga tatgttgact
     6721 cgtatccgca atgcgcaacg tgctaataaa gcagcagttg caatgccttc ttcaaaatta
     6781 aagtgtgcta ttgcaaaggt attgaaagaa gaaggatata ttgaggactt cgcagtttca
     6841 tctgacgtaa agtctatatt ggaaattcaa ttaaaatact atgcaggtcg tcctgtaatt
     6901 gaacaaatca agcgtgtatc tcgccccggt ttgcgtattt ataaagcgtc tagtgagatt
     6961 ccaagtgtta tgaatggctt gggtattgct attgttagta cttctaaagg tgtaatgact
     7021 gatcgtaaag cacgttctca aggtgttggt ggtgagttgt tatgcattgt agcctagtgg
     7081 aggaaaagaa atgtcacgtg tcgcaaaaaa cccagtgact gttcccgctg gtgtagaagt
     7141 aaaatttgga acagaggcat tagttattaa gggtaagaac ggtgaattgt ctgttccttt
     7201 gcattctgat gtagccattg aatttaatga tggcaaattg acttttgttg cgaataacag
     7261 cagtaaacaa gcaaatgcaa tgtctggtac tgctcgcgca ttagtcagca atatggttaa
     7321 aggtgtttca gaaggttttg agaaaagatt gcaattgata ggtgtgggtt atcgtgctca
     7381 agcacaaggt aaaatcttga atctgtcttt gggtttttct catccgatcg tatatgaaat
     7441 gcctgaaggt gtctccgttc aaactcctag ccaaacagag attgttttaa ccggctcgga
     7501 taaacaagtt gttggtcaag ttgctgctga gattcgtgcg ttccgtgctc ctgagcctta
     7561 taaaggtaaa ggtgttcgct atgtaggaga agtagtggta atgaaagaag ccaagaaaaa
     7621 ataattgagg ttcactaatg gataaacata caacccgact ccgtcgtgca cgcaaaaccc
     7681 gtgctcgtat tgcggacttg aaaatggtaa gattatgtgt gttccgaagc aataatcata
     7741 tttatgctca agtaattagt gctgaaggtg ataaagtatt ggctcaagcc tctacattgg
     7801 aagctgaggt gcgcggtagt ctgaaatctg gaagcaatgt tgaagcagct gcaatagttg
     7861 gtaaacgtat cgctgagaag gctaaagcag caggtgtaga aaaggttgct tttgatcgtt
     7921 caggtttcca atatcacggt cgtgtgaagg ctttggctga agctgctcgt gaaaatggtt
     7981 taagcttcta aatatttgga gactttcaga tggcaaaaca tgaaattgaa gaacgcggtg
     8041 acggtctgat tgaaaagatg gtcgcagtta accgtgtaac caaagtagtt aaaggtggtc
     8101 gcattatggc tttctctgcg ctaactgttg ttggtgatgg agatggtcgt attggtatgg
     8161 gtaaaggtaa gtcaaaagaa gtgcctgttg cagtccaaaa ggcgatggat caagcacgac
     8221 gctctatgat taaggtacca ttaaaaaatg gtacgattca tcatgaggtt attggtcgac
     8281 atggtgctac taaagtattt atgcagcctg ctaaagaggg tagtggcgta aaagccggtg
     8341 gacctatgcg tttggttttt gatgctatgg gcattcataa tatctccgcc aaagtgcacg
     8401 gatctactaa cccatataat atcgtacgtg caacattaga tggtttgtct aagttgcata
     8461 ctcctgctga tatcgcagcc aaacgtggct tgacagtgga agacattttg ggagttaacc
     8521 atggctgaac aaaaaaagat tagggttaca ttggttaaaa gcctgattgg tacaattgaa
     8581 tctcatcgtg catgtgcacg cggtttaggt ttgcgtcgtc gcgagcatac ggtagaggtt
     8641 ttagataccc ctgaaaaccg tggtatgatt aataaaatca gctacttgtt gaaagtggag
     8701 tcttgatatg tttttgaata caattcaacc tgctgttggt gctacgcatg ctggtcgtcg
     8761 tgttggacgc ggtattggta gtggtcttgg caaaacgggt ggtcgtggtc ataaaggtca
     8821 aaagagccgg tctggtgggt ttcataaggt gggtttcgag ggtggtcaaa tgcccttgca
     8881 acgacgcctc cctaaaagag gttttaaatc tttaacagca tcagctaatg cacagcttcg
     8941 tttaagtgaa ctggaatcaa ttgctgttaa tgagattgat attttggtct taaagcaagc
     9001 gggtctgatt gcatctacag tctctaatgt taaagttatt gcttctggtg aaatttctaa
     9061 ggcagttgct ttgaagggta ttaaagttac caaaggtgcg agagctgcta tcgaggctgt
     9121 tggtggtaag attgaaatgt aaggtttaat attgtggcta atcaacaaac gtcatcaggt
     9181 tcatccaaat ttggagatct taagaaacgt cttttgtttc tatttggagc attgattgtt
     9241 tttcgaattg gtgcccatat acccgtacct ggagttgatg ctgttgcttt agctaaatta
     9301 tacgaaagcg ctggaaacgg catcctggga atattgaata tgttttccgg tgggtcgtta
     9361 gagcgcttta gtatatttgc aataggaatt atgccatata tttcagcttc tattattgta
     9421 cagctcgctt ctgaaatttt gccatcattg aaggctttaa aaaaagaagg ggaggctggt
     9481 agaaaggtaa ttacgaaata tactaggtat ggtactgttt tgttagcaat tcttcaaagt
     9541 ctaggtgttg catctttcgt atttcagcaa ggaattgttg taacaagttc atttgagttt
     9601 catgtttcca cggtagtttc tttggtaacg ggaaccatgt ttcttatgtg gcttggggag
     9661 caaattactg aaaggggtat cgggaacggt atttctttaa tcattacggc aggtattgct
     9721 tcaggtattc cttcgggtat tgcaaagctg gttacactga cgaaccaagg ttctatgagc
     9781 atgcttacgg cgttgtttat tgtatttggt gccttattat taatttattt ggttgtatac
     9841 tttgaaagtg cacagaggaa gattcctatt cattatgcaa aacgccagtt taatggtagg
     9901 gcgggtagtc aaaatacgca tatgcctttc aagttgaata tggctggtgt tattccccca
     9961 atttttgctt ccagtattat tctatttcca tctactcttt taggttggtt tggttcggct
    10021 gatacaaata gtgttttgca caaaatagct ggattgttac aacacggtca attgctgtat
    10081 atggctttat ttgcagcgac agttattttc ttttgttatt tttatacggc tttggttttt
    10141 agccctaaag aaatggcaga gaatttaaaa aagagtggtg cttttgttcc tgggattaga
    10201 cctggtgagc agacctctag gtatttagaa aaagttgtat tacgtttgac attgtttgga
    10261 gctctttata ttacaactat ttgtttaatt ccagagttct taactacggt tttaaatgta
    10321 cctttttatt tgggtggcac gtctttgttg attctagttg ttgtaacgat ggattttagt
    10381 acacaaataa attcgtatag gcttactcaa cagtatgata agttaatgac tcgttcagaa
    10441 atgaaatcat tttctcggaa atagaattat ggcgaaagaa gatactatcc aaatgcaagg
    10501 tgaaattctt gaaactttac ctaatgcaac atttaaagta aaacttgaga atgaccatat
    10561 tgtattgggt catatttctg ggaagatgcg gatgcattac attcgtattt ctccgggaga
    10621 taaggtcaca gtagagctga caccttatga tctaactagg gctcgaatcg ttttcagagc
    10681 aagataaacc aataaaagga aaataaaatg cgtgtacaac catctgttaa gaaaatttgc
    10741 cgaaattgca agattattcg tcgaaatcgt gtagttcgtg taatttgtac tgatctccgt
    10801 cacaaacagc gtcaaggtta atggaatatt tcttttaatg tgattctgtg atatagtgac
    10861 acactttgcc ctaaaaagga aaaaatatgg ctcgtattgc aggggtaaat atccctaata
    10921 acgcacacat cgtaattggt cttcaggcta tttacggtat tggtgctact cgtgctaaat
    10981 tgatttgtga ggctgcaaat attgcgcctg atactaaagc aaaagatttg gacgagactc
    11041 aattagatgc tttgcgtgac caagttgcca agtatgaagt agaaggtgat ttgcgtcgtg
    11101 aggtaactat gagtatcaag cgattgatgg acatgggctg ctatcgtggc ttccgtcatc
    11161 gtcgcggctt accatgccgc ggtcaacgca ctcgtacaaa tgcgcgtacc cgcaaaggtc
    11221 cgcgtaaagc gattgctggt aagaaataaa ttttaaggaa ttttattaat ggctaaagca
    11281 aacacagctt cacgtgtacg taaaaaagta cgtaaaaccg tgagtgaggg tattgtgcac
    11341 gttcatgcat ctttcaacaa taccatcatt acaatcactg accgtcaagg caatgcgttg
    11401 tcttgggcta cctctggcgg cgctggtttt aaaggttctc gtaaaagtac accatttgca
    11461 gcacaagttg cagcagaagc agctggtaaa gttgcccaag agtatggcgt taaaaattta
    11521 gaggttcgta ttaaaggtcc aggtccaggt cgcgaatcct ctgtacgtgc tttgaatgct
    11581 cttggtttca agattaccag cattactgac gttaccccgt tgcctcataa cggttgccgt
    11641 ccgcctaaaa aacgtcgtat ttaatattgg agtgatttga aacatggcac gttatattgg
    11701 ccctaaatgt aagttggcac gtcgcgaagg tacggatttg tttttgaaga gtgcgcgccg
    11761 ctctttggat tctaaatgta aaattgattc cgctcctggt cagcatggtg caaaaaaacc
    11821 gcgtttgtca gactatggtt tgcagttgcg tgaaaaacaa aaaatccgcc gtatttatgg
    11881 cgtattagaa cgtcagttcc gtcgttattt cgcagaagct gatcgtcgta aaggttctac
    11941 cggcgagttg ctgttgcagt tgctggaatc tcgtttggat aatgtcgttt atcgtatggg
    12001 tttcggttct acccgagctg aagcaagaca gcttgtttct cataaggcga tagttgtgaa
    12061 tggacaagtt gtcaatattc cttctttcca agtgaaagct ggtgatgttg tctcagttcg
    12121 tgaaaaagcc aaaaaacagg tacgtattca agaagcattg ggtttggcaa ctcaaatcgg
    12181 cttgccgggt tgggtttctg tagatgcgga taaacttgag ggtgtgttca aaaacatgcc
    12241 ggatcgctcg gaattgaccg gtgatattaa tgaacagctg gtggtagagt tctactctaa
    12301 ataatgctag ctcagtgagg gacagttaaa tgcagaatag cacaaccgaa tttttgaaac
    12361 ctcgtcaaat tgatgtaaat actttttctg caactcgtgc aaaagtatct atgcagccat
    12421 ttgaacgtgg tttcggtcat accttaggta atgctttgcg ccgtatctta ctgtcatcca
    12481 tgaatggttt tgctcctact gaagtagcta ttgccggtgt attacacgaa tattctactg
    12541 ttgatggtat tcaggaagat gttgttgaca ttttgctgaa tattaaaggt attgtgttta
    12601 aactccatgg tcgtagccaa gttcaacttg tgttgaagaa atcaggttca ggtgtcgtat
    12661 ctgccggtga tattgagttg ccgcatgatg tagaaattct gaatcctggt catgtcattt
    12721 gtcatttggc tgataacggt caaattgaga tggaaattaa agtagagcaa ggtcgtggtt
    12781 atcaatctgt ttcaggtcgt caggtagttc gtgatgagaa ccgtcagatt ggtgcaatcc
    12841 agttggatgc gagcttttcg cccatcagcc gtgttagctt tgaggttgaa cctgcacgtg
    12901 tagagcagcg gacggatctt gataagttgg ttttggatat cgaaaccgac ggttctattg
    12961 atcctgagga agctgtacgc agtgcggcac gtattttgat tgatcagatg tctatttttg
    13021 ctgatttgca gggtacgcct gtggaggagg ttgaagaaaa agcacctcct atcgaccctg
    13081 ttcttttgcg tccggtggat gatctggaat tgacagtacg ttcagctaat tgtttgaaag
    13141 ctgaggatat ttattatatt ggcgatttga ttcaacgcac tgaaaccgag cttcttaaaa
    13201 cgccgaattt gggacgtaaa tctttgaatg agattaagga agtattggca tctaaaggtt
    13261 tgacactggg ttctaagttg gaagcatggc cacctgtagg cttggaaaag ccttaatgaa
    13321 gaattaaagg ataattgata tgcgtcatcg taatggcaat cgcaaattaa accgtaccag
    13381 cagtcatcgt gctgcaatgc tgcgtaatat ggcgaattca ttattgactc acgaaactat
    13441 tgtaacaact ctgcctaagg ccaaggaatt gcgccgtgta gtagagccgt tgattacatt
    13501 gggtaaaaag ccgtcattgg caaaccgccg tttggcattt gaccgtactc gcgaccgtga
    13561 tgttgtagta aaactgtttg gcgatttggg tcctcgtttt actgctcgta acggtggtta
    13621 tgttcgggtg ttgaaatacg gattccgtaa aggtgataat gcacctctgg cactggttga
    13681 attggttgac aaaccggctg ctgagtaatt ttagtcatat aacgccatct gccgaaaagc
    13741 aggtggcgtt atttttgcaa tatctgatag gtaatagggt attggctatc atgtttaaaa
    13801 tattaattga atagctaagg tttgcgcggt aaacttacat cattaaaaaa ttctatgatg
    13861 gtttatataa tgaatgcttt cgatataaag tcgacaaaga tggacgtatt gtctatatct
    13921 ttgcatacgt cagacttgtt tgatttggaa gatgtgctgg tcaaattggg caagaagttt
    13981 caagagtctg gtgttgttcc atttgtgctg gatgttcaag agtttgatta tcccgagtct
    14041 ttggatcttg ctgcattggt ttcgttgttt tcaaggcatg gtatgcaaat tttgggtctg
    14101 aagcattcta atgaacgttg ggctgctgcg gctatgaagt atcatttgct gttttgtctg
    14161 tctcattcgg aaaatgttaa agaactgggt caggttgagg tgcagaacac ggaggatggt
    14221 cagaaagcaa ggaaaacagt attgattaca tcccctgtcc gtaccggtca gcaggtttat
    14281 gccgaagatg gcgatttgat tgttacgggg gcggtcagcc agggggcgga attgattgca
    14341 gatggcaata tgcatattta tgcgccgatg agagggcgtg ctttggccgg tgccaaaggc
    14401 gatacttctg cccgcatatt tatccactcc atgcaggcag aactggtttc tgtggcgggt
    14461 atttaccgta attttgaaca ggatttgccg gaccatctgc acaagcagcc ggtacagata
    14521 ttgttgcagg ataaccgatt ggttatcagt gcaattggct cagaataatt gtttgatatt
    14581 ttaaaaagga aatattgtgg caaaaattat tgtagtaact tcaggtaagg gcggtgtcgg
    14641 taaaacgact accagtgcca gtattgcgac aggtttggca ttacgcggat ataaaactgc
    14701 ggtaattgat tttgatgtgg gtttgcgtaa cctcgacctc attatgggtt gcgagcgtcg
    14761 tgtcgtttat gacctgatca atgtcattca gggggaggcg acgctcaacc aagctttgat
    14821 taaagataaa aattgtgaaa acctgtttat tttgccggct tcccagactc gggataaaga
    14881 cgctttgaca cgcgagggcg tagaaaaagt gatgcaggag ctgtccggca agaaaatggg
    14941 ctttgagtat attatttgcg actctcctgc cggtattgag cagggtgcat tgatggcgtt
    15001 gtattttgct gatgaagcca ttgtaacgac caatcctgag gtttccagtg tgcgtgactc
    15061 cgacaggatt ttgggaattt tgcaaagcaa atcccataag gcagagcaag gcggttcggt
    15121 taaagaacat ctgttgatta cgcgttattc tcccgaacgt gtggcaaaag gcgaaatgct
    15181 gtctgtacag gatatttgcg atattctgca tatccctttg ctgggtgtga ttcctgaatc
    15241 ccaaaacgtc ttgcaggcat ccaattccgg agaaccggtc atccatcagg acagcgtggc
    15301 ggcttccgag gcatataagg acgttattgc ccgtcttttg ggcgagaacc gtgaaatgcg
    15361 tttcttggaa gctgagaaaa aaagcttctt caaacgtctg tttggaggat aaggtatgtc
    15421 attaatcgaa tttttattcg gcagaaagca gaaaacggca accgttgccc gcgaccgcct
    15481 tcaaatcatc attgcccaag agcgcgccca agaaggtcag gctccggatt acctgccgac
    15541 tttacgtaaa gagttgatgg aagtcctgtc caaatatgtg aatgtttcat tagacaatat
    15601 ccgtatttcc caggaaaaac aggatggtat ggatgtgctt gagttgaaca ttactttgcc
    15661 ggaacagaaa aaggtatagg acatgacctt aaccgaattg cggtacatcg tcgcagtcgc
    15721 ccaagaacgt catttcggca gggcggcgcg gcgttgtttt gtcagccagc ccactttgtc
    15781 tattgccatt aagaaattgg aagaagagct tgccgtctct ttgtttgacc ggagcagcaa
    15841 cgatattatt acgaccgagg cgggggaacg tatcgttgca caggcgcgta aggtgttgga
    15901 agaggcagag cttatcaggc atttggcaaa tgaagaacaa aacgagctgg agggtgcgtt
    15961 caaactcggg ctgattttta cggttgcgcc gtacctgctg ccgaaactga ttgtctcgtt
    16021 gcgccgtact gcaccgaaaa tgcctttgat gttggaagag aattacacgc atactttgac
    16081 cgagtcgctc aaacgcgggg acgttgatgc gattatcgtt gccgaaccgt ttcaagagcc
    16141 gggcattgtt accgaaccct tgtatgacga accgtttttc gtgattgtcc cgaaagggca
    16201 ttcatttgag gaactggatg ccgtttcgcc ccggatgctg ggtgaggagc aggttttgtt
    16261 gctgacggaa ggcaactgta tgcgggatca ggtactctca agctgttccg aattggcggc
    16321 gaaacaacgt atacaggggt tgaccaatac attgcagggc agctcgatca atacaatccg
    16381 ccatatggtc gccagcggtt tggcaatcag cgtgttaccg gcaaccgcgc tgaccgaaaa
    16441 cgatcatatg ctgttcagca ttattccgtt tgagggtacg ccgccaagcc ggcgggtcgt
    16501 attggcgtac cgccgcaatt ttgtccgtcc gaaggcgttg tcggcgatga aggcggcgat
    16561 tatgcagtcg cagcttcacg gggtaagttt tatccgcgac taggcgcagg cattgttttc
    16621 aaaacgccat ttccctgagc cgacaacacg gtatgccaag atattgccgt catcatcgat
    16681 tttgagtata gcatcgccac ggaaactgcc gtcctgaaga tattcgactt ttgcatcact
    16741 gtgaatgttt tcatcagtgc cgatgcaatg ccatgtatag tggattaaca aaaaccagta
    16801 cggcgttgcc tcgccttgcc gtactattgc caaggcgtac cagcctgatt tgttgatgtg
    16861 tgtactactg catgggttgt taagccctgc aagtgattta agtgtgaaga ttgagtaatg
    16921 cccactagtc gcaggcgcgg ggggcaggtg ctaagtcatt ggttatctcc ttactatcta
    16981 tctaactaca gggtgtatta tgcgcctcct tgttgttttg tgcaattggt tttctgataa
    17041 tttatgtaaa gatttggtaa agacgtatag cctttttctt tgcattgtgc ttgcgcaggg
    17101 tatcaggtag gtctcaaaaa atttgaaaat ttttatgttt tcgtataaaa tcttttgcac
    17161 ttatacggag tgagttatgc ggtacaccat taaaacattt caaacccttg ctgatgaaac
    17221 tttcccctct aagaacttca aaattctttc gttcaatggg gtggcacgac ctataaccat
    17281 tgtttgccct acacacgggg tgcagactgt ttctgcgggg caagcattta tccgttccaa
    17341 acacggctgt cctgcctgtg gtttagtttt atcaacctcc gttttggcct ctaggggtcg
    17401 gtcagtctcc atcctcgaca ccgccacagg cgaaacactc tcgttcccca gcgtacaagc
    17461 tgccgccaaa gccctaaaca cctcctacgg ctctatacga accaagctcg acggacgttc
    17521 gtcccccgac aaccttgtct gtaacaggta caaagtaatg ccgtaatctc gaaacttcgt
    17581 gctataataa actcctagct tttgcaggag tttgtttttt atggatttaa atgtcgaaat
    17641 caagaatttt ggcaaggttg cccatgctag ggtttccatt cgcccgctta ccgtcatcac
    17701 gggttgcaac tccacactcg cgttccccag cgttactgcc gcaggcactg ctttgggtgt
    17761 gcattttcag caaattaacc acaggctcaa gggtcgaacg tcctgtcagg aggtgttgat
    17821 ttctacaccg attatactgt ctgcggcttc gtcgccttgt cctgattttt gttaatccac
    17881 tataaaagag gccgtctgaa aaacattttt cagacggcct tgttgattca atcaaatcag
    17941 tctttcaact tcgacaactg agtttgcact tttgccattt tgtcttccaa ttccgccaaa
    18001 tcggctttgt ctttttccac caaatgcgcc ggggcttttt cggtgtagcc gggtttggag
    18061 agtttggcgt tgagtttgtc caaggctttt tgcagcttct cggcttcttt gctcaagcgg
    18121 gcggtttccg cggctttgtc gatttcgact ttcagcatca ggcgcgcgcc gttgcagacg
    18181 gcgacgggcg cgtcttcgct ttcgggcagg gcggcgactt gccgtgcttc ggtcaggcgg
    18241 gtcatcatcg gcaggtattt gaggtagtcc gccaagtcgt ccgcgctttc gacaaacagc
    18301 ggagctttga cattaggctg gatgcccatt tcgccgcgca ggttgcggac tgcgccgatc
    18361 aaatcctgca acacggtcat ttgctcgaat gccgtctgaa caatctcgcc gccgtcggct
    18421 tcggggaagc gggcgagcat gatgctgtcg gcggttttcg cgtcgcacat aggagcgacg
    18481 gtttgccaca attcttcggt gatgaacggg ataatcgggt gcagcaggcg cagggcggct
    18541 tcgagtacgc gcaataaggt atggcgtgtg gcgcgttggc ggctggcgca gccggtttga
    18601 agctgcactt tggcaagttc cagataccag tcgcaatagt cgttccacac gaagctgtac
    18661 agggtttctg ccgccaaatc aaagcggtag gtttcgtagg cttgcgttac ttgctcgatg
    18721 gtctgattca gacggcctac aatccacata tcggggaagg agtagccgcg cggttcggtg
    18781 gcggttgcgc cgtagccgca gtcttggttt tcagtgttca tcaagacgaa gttggtggcg
    18841 ttccagattt tgttgcagaa gttgcggtag ccttcggcgc gtttgaagtc gaagttcacg
    18901 ctgcgcccca agctggcgta gctcgccatg gtgaagcgca aagcgtccgc gcccatactg
    18961 gggatgcctt cggggaagag ttttttcgtg gcttcttcca ctttcggcgc ggtttcgggt
    19021 ttgcgcagac cggtcgtgcg ttttaccagt agcttgtcca agtcgatgcc gtcaatcaaa
    19081 tcgacggggt cgatgacgtt gccttcggat ttggacattt ttttgccttc atggtcgcgc
    19141 acgatgccgt ggatgtacac gtctttaaac ggtactttgc cggtgaagtg ggtggtcatc
    19201 ataatcatgc gcgccaccca gaagaagatg atttcgtagc cggtgaccaa gacgttggac
    19261 ggcagaaagg ctttgagttc gtcggtttca gacggccagc cgagcgtgga gaacggcacg
    19321 agtgcggagg agaaccatgt gtccaatacg tcttcttctc gggtcaagcc tgttttgccg
    19381 gcttgttttt cggcttcttc ctgattgcgg gcaacgtaca cattgccttc gttgtcgtac
    19441 catgcaggga tttgatgccc ccaccacagt tggcgcgaga tgcaccagtc ttggatgttg
    19501 ttcatccatt ggttgtaggt gttgacccag ttttcgggga taaagcgcac cgcgccgctg
    19561 tcgacggctt ttttggcttt gtcagcaagg cttaagcctt tgaattcgct gtcaggctcg
    19621 ccgccgtttg gcgtggcgga catggcgaca aaccattggc tggtcagcat cggctcaatc
    19681 acggaaccgg tacggtcgcc tttcggcgtc atcagcgtgt gcgctttgat ttcgaccaag
    19741 aaaccttgtt cctgcaaatc ggcaaccatt tgtttgcgcg cggcaaagcg gtccaagcct
    19801 gcgtattttt caggcagggc aaagcttggt tgcgcttcgc ctttgaagtt gaacacttcg
    19861 gcgtttgcca atactttggc ttccaagtcg aacacattaa ccaagcgcgt atcgtggcgt
    19921 ttgccgactt cgtagtcgtt gaagtcgtgc gcaggcgtga ttttcacgca gccggtgccg
    19981 aagtcttttt caacgtattc gtcggcaatc acgggaatgg tgcggccggt cagcggcagg
    20041 attaattctt tgccgattaa gtgggtataa cgttcgtctt cgggattgac ggcaacggca
    20101 acgtcgccca acagcgtttc gggacgggtg gtggcgacga tgacggcttc ggcaggattg
    20161 tccgccagcg gatagcggat gtgccacata gagccttgtt cttccacgct ttccacttcc
    20221 aaatcagaca ctgcggtacc caataccgga tcccagttca ccaagcgttt gccgcgataa
    20281 atcaagccct gttcatacag gcgtacgaac acttcggtta cggtttcggc gcgtacatcg
    20341 tccattgtga aatactcgcg cgtccagtcg gcagaacagc ccacacggcg catctgctgc
    20401 gtaatcgtgc cgccggaaac ttctttccat tcccacactt tttccaagaa tttttcacga
    20461 cccaagtcat gacgggacac gttttgcgcg gcaagctgac gctcgaccac gatttgcgtg
    20521 gcgatgcccg cgtggtcggt gccgggaatc caggcggtgt tgcagccttt catacggtag
    20581 tagcgggtca ggccgtccat aatggtttgg ttgaaggcat gacccatgtg cagcgtgccg
    20641 gttacattgg gcggcggcag ttggatggaa aaagacggtt tggtcaaatc catatcaggt
    20701 tggaaatagc cctgctcttc ccagttttga taatgtttgg attcgatttc ggcgggggag
    20761 tatttgtcta acatgatgga actttgtgaa attaaggtta tttttgatgt gcggattata
    20821 acgcaaaaag gccgtctgaa tcatttcaga cggcctttgg catacaggtt ttaaaaatgg
    20881 aacaatacca ggctgacggc aatcaccgcc atgcccattg tcaggccgta aacggtttca
    20941 tggccgtctg aatagcgttt ggcagccggc agcagctcgt ccaacgccaa aaacaccatc
    21001 acaccggcta tcacgccgaa taccgaacca aacacggcag gcgacaaaaa cggctgcaaa
    21061 accaaatagc ccaaagccgc ccccaacggc tcggccaagc cggatagcag acacgcccac
    21121 accgttttct tacggctgcg ggtggcaaaa taaaccggcg cggcgatgga aatgccctcc
    21181 ggaatattat ggatggcaat cgccaaggcc aaaggcatcc cgactgctgg attttccaat
    21241 gtggcaaaaa acgtcgccaa gccttcgggg aaattgtgcg cagtaatcgc aaacgccgcc
    21301 atcatgccga ctcgcgcgat atggcggcgt ttgctttctt gaaacgacgg gtcttgcgcg
    21361 tctaaagttt catgcgggtt cggcaccaga cggtcaatca gcgcaatgcc gcccatccct
    21421 gccaaaaatg ccatggtcgc cgccgcaaac gcgtggtctt tatcataaat ttcagcgaac
    21481 gcctcgctgg acttactgaa aatctccgtc agggaaacat acaccatcgc accgccggca
    21541 aatgccaaac caaacgacaa cacgcgcgga ttgggcgttt tggaaaacat caccaagccg
    21601 ctgcctaata cggtaaacaa accggcagcc aacgtaatgg aaaaggcaac ggccaaattg
    21661 gacatcgaaa aatcgggcat gggaaaacct gcgctaaaag ctgggacagg ttcagactaa
    21721 cactttttaa tgcgtatgat aatagttatt atttatttta ttgattggat acccgaattt
    21781 tgaaacaaaa ggccgtctga aaaatgattt tcagacggcc tttaaatttg aaatgtcgct
    21841 aaaccttatc gctttccagc ttaagcctga tagcgcgaca ggctcaaatc gtcgcttcgg
    21901 atttcggtgt ctttgccgct cacgatatcg gcggttaatt ttgccgaacc cagcgacatg
    21961 gtccagccca aagtgccgtg gcctgtattc aagaataagt tttcaaagcg ggtgcggccg
    22021 attaacggcg tgctgtcggg cgtcatcggt ctgaggccgc tccagaacaa tgcttggctc
    22081 aaatcgccgc cttccgggaa caaatcgttg acgaccaaag ccaaggtttc gcggcgtttt
    22141 tcgggcagtt tgatttcgta gcccgacaat tctgccatgc cgccgacgcg gattctgttg
    22201 tcaaagcgcg tgatggcgac tttgtagctt tcatccaaaa cggtggacac cggcgcgccg
    22261 tctgaattgg tgaccggcag ggtcaaggaa tagcctttga cgggataaat cggcagatcg
    22321 aggtctaact gcgccaacac agtcctactg aagcagccga gcgcacagac aacggcatct
    22381 gcttcaaacc gccctgtttc ggtttcaacg gctttgatgc gcagcccgtt atggtcgatg
    22441 cggctgatgg tttggttgaa atgaaactgt acgccctttt cctgacacaa tttgtatagg
    22501 ttttcagtga agaggtggca gtcgccggtc gcatctgcag gcaggtgcag gccgccggca
    22561 attttggcgg taacgcgtgc cagcgcaggc tcaaattctg cacattcttc gggtttcaga
    22621 cggcggtacg gcacgccgta gcgttccaaa acggcaatgt cttgttctgc cgcttcgact
    22681 tctttggttt ggcggaaaat ctgcaacgtc ccttttttgc gttcctcaaa attcatgccg
    22741 gtttgcgctt caaaacggcg gaacatttca cggctatatt cggaaatcct gaccatgcgc
    22801 tctttattgg tttgatagtg cgctgccgtg cagttttgca gcatccgcca cagccattcg
    22861 atttgataca ggctgccgtc ggggcgaaac agcaaaggcg gatggctttt aaacagccat
    22921 ttcagtgctt tggtcggaat accgggtgca gcccaaggcg tggtatagcc gtaagaaagc
    22981 tggcctgcat tggcaaaact ggtttccatc gccacaccct tggcgcggtc gatgaccgtt
    23041 acttcatgtc cggcctctgc cagataccac gcggaagaca cgccggcaac acccgcacct
    23101 aaaacaagca ctttcatgtt tctccctccg actttttcaa aacagactta atatgccgtg
    23161 ccgtctgaat attcggattc agacggcctc ggatattaat gcggcaattc gccatttgtg
    23221 attttttgtt tgaagtcgcg cgtttcattg acgatgactt tcgccatcaa taaaagtgca
    23281 atcaggttgg gcaatgccat caagccgttg aatgtgtccg aagccagcca caccaaatca
    23341 aggctcaaca cggtacctag cataacggaa gaaacataac cgacgcggta caaaccggca
    23401 aatttctcgc cgaaaacata caccgcgcat ttttcgccgt aatagcacca gcccaaaatg
    23461 gttgagtagg caaagaaaat caggccgatg gtgacaatcc agccgccgat gccgggcagc
    23521 attttttgga atgtgacggt tgtcagtgcc gcgccgctca cttcaggttt gacaaactcg
    23581 ccgcccgcgc cgagcagtcc cattaccaac acgatgccgg taatcgagca aacgacgatg
    23641 gtatccaaaa acgtaccggt catagaaacc aaggcctgac ggacgggatg gtcggttttc
    23701 gcggctgcgg cggcaatagg cgcagaaccc atacctgcct cattggagaa cacgccgcgc
    23761 gccacgccgt agcggatgac cgtaccgata gcaccgcccg ccactgcctg cgcgctgaac
    23821 gcatcggaga aaatcagctt gacggcaggc atcagtgcat cggaattaat cgcgataatg
    23881 gaaagaccgc ccaacacata aaacaccgcc atagcaggca cgatgaaaga agcggctttg
    23941 gcgatgcctt taataccacc taaaacgaca acggcagtca gaacggtcaa cgtaatgccg
    24001 gtataggcag gttcgatacc gaagctggtt tgcaccgcct gtgcaaccga gttggactgc
    24061 accgagctgc cgataccgaa ggaagcgaat gtgccgaaca gcgcaaatgc aacggccatc
    24121 catttccagt ttttgcccaa gcctttttcg atgtaataca tcgggccgcc ggacatttcg
    24181 cctttggaat tgttgacgcg gtatttcacc gccaacacgc cttcgccgta tttggtggcc
    24241 atgccgaaaa tggcggtcat ccacatccaa aataccgcgc ccgggccgcc ggttaccacc
    24301 gcagtcgcca cgccggcgat gttacccgtg ccgatggtgg cggacagcgc ggtcatcaac
    24361 gccgcaaaat gggaaatatc gccttcgtgg ccttcgccgc ttttatgctt ctttggcggc
    24421 ataaacgcct gtttcagcgc ataacccaac atcgtgaact gcaaaccttt taataaaaca
    24481 gtcagcaaaa tacccgtgcc gaccagcagc atcagcatca aaggtcccca aacccagccg
    24541 ctgacggttt caaaaaaggc tttgggattg tctaaaaaca cttgcatggc tttctccttt
    24601 gtctgtttta tttttaaaac accacttttg tagtgtccag taatttcagc acagaatatc
    24661 caataagaca atatgttctt ttgaaaaata cttttggttt tttcgccgaa aacaggccgg
    24721 ttcaagctgc ggaaattgtt tgtaattctt taaaagcagc ggcggaggtc acaatgaaat
    24781 gtccgaatgg ggatgtggcg ggcggcagaa atcatcaatg ctgccgactg ccatacttct
    24841 gaaatctaca aaatgatgca tcgatcaaac aatataccgc tttaaaaaaa ccgatgccgt
    24901 ctgaaacgct gtcggggttt cagacggcat caaaagggta cggtcagcgg atgatgccgc
    24961 gcgtcgattg tgcgaaaaag tctcggaata cggcaagctc ggcttgggtt tcggcgcggc
    25021 ggaggatgtc tgccttggct tcttcaaacg gaatgccgcg atggtagagg gttttgtaca
    25081 cgtttttgac ggcggaaatc tgctctgcgg taaaaccgtt gcggcgcatg ccttcgctgt
    25141 tgagccccgc cggttcggcg cggtagcccg atgccataaa gtagggcggc acgtctttgt
    25201 gtacgcctgc ggcaaacgcg gtcatggcgt agtcgccgat gcggcagaat tggaaaacca
    25261 gcgtgtagcc gcccaaaacg acgtagtcgc cgacggtaac gtgtccggca agcgaggcgt
    25321 tgttggcgaa gatggtgtgg ttgccgacca cgcagtcgtg cgcgaggtgg cagtacgcca
    25381 taatccagtt gtcgtcgccg atacgggttt cgccgatgcc ggttaccgtg cctaaattaa
    25441 aggtggtgaa ttcgcggatg gtgttgccgt tgccgataat cagcttggtc ggctcgtcgc
    25501 ggtatttttt gtcctgcgga atttcgccga ggctggcaaa ttggaaaatg cggttgtttt
    25561 cgccgatgct ggtgtggccg ttgatgacgg cgtgcgggcc gatttcggta ttcgcgccga
    25621 tttggacgtt ggggccgata acggtgtacg cgccgacttt gacgctggag tcgagttcgg
    25681 ctttggggtc gatgacggcg gtcgggtgga tgagggtcat gttttgaata ctccgctgct
    25741 tgttaagaca aataatagaa aattacagtt tgtcgatttc atcgcagacc gcaatcactt
    25801 gatcgctaaa atggctaaat actgaagcag tatctacatc catgtaatta agcagttcaa
    25861 aaatagattg gtgaatattt ctagcgtagt tggtatcttt tattgcacct ttaaaacaaa
    25921 tcggctcgtg atgtgccaaa cgattacgga atttgttaat attggaaagt tctcgaaaaa
    25981 tccatttttg gttatattgc acacttggtg tagatttggg cttttttgga aaaactttca
    26041 tcaatacttt ccctgtagca tcaaattggg catctttccc tcctgcaaac agataccgcc
    26101 aaaaaccgaa tcctagtcct gcaaccaatt ggttgtggtc aaactttccc ccgctattat
    26161 tttgtatttt agataatgca accttgatta attcagcaga ttctttcgtg ccatttctta
    26221 aaaagcaacc ttgatatttt aatgcgggat tcgtctgtgg ctgtatgctg ttatataacc
    26281 agtttctgtc tttaaacgcc tgctgaaggc aaatgtcaat tttgtttctt aaaacaatct
    26341 caaatattga aacaacatga aaaagttctc ttgataaaga taaattcaat aaatacaatt
    26401 cagctgcttt gtcttcccca acggcatttt tataccgttc cattctgaaa tcagaaaaaa
    26461 tactacagca ttccttataa tccacgctaa cacctgattc tttattttta aattgacgtt
    26521 tcaaactata tttgatacag ttaggtaaaa ctaatcccca ccgtgtccct gggtttgaat
    26581 aaacctaaac cggtgggttt tctttttatt aggtcgtctg aaactttcag acgacctttt
    26641 tccgaacgct caaaccacgc gtttggcaca catgatgatg gcttcgacgg cgacttgccc
    26701 gtccactttg gcaacggcgt tgaatttgcc gatgccgcgc cggctggtca gcagctcgac
    26761 ttcaaagacg agttggtcgc cggggatgac ttggcgtttg aaacgggctt cgtctatgcc
    26821 ggcgaagaag aagaattcgt tttctttgcg cccgccttcg ctgaggatgg cgagtgtgcc
    26881 gcaggcttgc gccatcgctt cgatgatgag tacgccgggc atcacgggca ggtcggggaa
    26941 atggccttgg aactggggtt cgtttatggt gacgtttttg atggcggtca gggttttcat
    27001 ggactcgaag gcggtgatgc ggtcgagctg gagaaacgga tagcggtggg ggatgagttt
    27061 ttggatgtct ttggcttcga tggggagttg tacgtccatg tctgtcgtat tccttgaata
    27121 aaatcggttt ggatttattg cgtgtctttg ccgtctgaaa gctgctgttc cagcgttttg
    27181 aggcgtttgt tcatttcgct taagcggtgg atgtaaacag cgttgcgcgc ccattcttta
    27241 tgggtggaca tcgggaagat gccggcgagg tgtttgccgc tttcggtaat gctgtgggtg
    27301 acggacgtgc cgccgccgat ggtggttttg tcggcgattt cgatgtgtcc gaccgtgccg
    27361 acaccgccgc cgatgatgca gtagctgcct atggttacgc tgcctgagat gccggttttg
    27421 gcggcgatga cggtgtgcga accgattttg cagttgtgtc cgatttggac ttggttgtcg
    27481 attttggtgc cgttgccgac ggtggtgtcg ctcatcgcgc cccggtcgat gttggtgttc
    27541 gagccgattt ccacgtcgtc gcccagcgtt accgcgccgg tttgcgggat tttaaaccac
    27601 gaatcgccgg cgaaggcgag tccgaaaccg tccgcgccga tgactgcgcc gctgtggatt
    27661 tcgacgcgtc tgcccagtgt acagccgtaa taaacgacgg cgttggggtg catgacgact
    27721 tcgtcgccca gtttgcaatc gtgttggacg acggcgtttg ccaagatgcg gcagccttcg
    27781 ccgagcacgg tgtttgcgcc gatgtaggcg ttcgcgccga tttcgcagct tgcgggaacg
    27841 gtcgcgcccg gttcgacgac ggcggtcgga tggatgccgc cgtgcgcttt gacgacgggt
    27901 gaaaacaggc gggcgacttt ggcgaaatag agataggggt cgtcggcgac aatcaggttg
    27961 cgcccttcaa atccgtctgc cgctttggcg gaaacgatga ccgcgcccgc gctgctgtcg
    28021 tggacttcgg ctttgtattt cggattggcg aggaagctga tgtgttccgc ctgcgcgtct
    28081 gcgagcgggc gcacggtggt aacggaaatg tcctcgccgc gccattcgcc gccgagccgc
    28141 gcggtgattt gggacagggt gtaggtggcc ggaatcatgg ttttcctgtt cggtatgccg
    28201 tctgaaaggg tcagcgggcg ttcatttctt taatgacgct gtcagtaacg tcgtattggg
    28261 tgttgacgta aatcacgttc tgcaaaatga catcgtaacc ttcctgtttg gcgattttga
    28321 cgatgacgcg gttggcgttt tgctggaggg aggcaaactc ttcgttgcgg cggaggttgt
    28381 agtcttcttc aaactgcgcc tgttttttgc ggaacgctgc gaccagcccg cgccattttt
    28441 cttcggcttg cgcctttttt gcgtttctga gtttgccttc ggcaagctgc ctttccaaat
    28501 ccagaccttc gcgttgcagt ttttgcaatt cgtcctgacg ggcggaaaat tcgctgtcca
    28561 gcgttttttg aatcttgcgc gcctgcttgg attcgaggta gatgcgctcg gtgttgataa
    28621 agccgatttt ttggaaggtg tcggcgtgcg cgcctgcggt gcagcacaaa ccgatcagag
    28681 ccgcggcaaa cgcgcgggtc aaacgggtca tggtaaaact ccttcgaatg ttgccgcgaa
    28741 atgccgtctg aagggcttca gacggcattt gcgggattag aacgtcgtgc cgagttggaa
    28801 ttggaagcgt tggatttcgt cttccggttt tttcttcagc gggtaggcgt agctgaattt
    28861 catcgggcct aaaggcgaga gccaggtaac cgcgccgccg gcggaatagc gcaattcgtt
    28921 ggtaaaggtg gatttatggg tattgccggc gccgtaaatg ttttgaaccc tgccgccggt
    28981 cgcggaactg ctgttgtcgt cgtaggtttt gccgtcccac acgctgcctg cgtcggcaaa
    29041 caggctcagg cggacggtgc gcgcgtcttt cgcgccgggc atcgggaaga gcagctcggc
    29101 ggagacgttg gcttttttgt tgccgccgta gctgattttt tcgccgtatt cgtcatagac
    29161 tttcggaccg agtgtgccgc tttcgtaacc tcgtaccgaa cccaggccgc cgccgtagaa
    29221 gttttcaaag aaggggattt ctttggtttt gccgtagccg ttggcatagc cgatttcgcc
    29281 gccaagcatc agtgtgaagg ttttgctcag ggggaagaac caggtttggt tgtgggtggc
    29341 ggagtagtat tgcagtttgc tgccgggcag ggcgatttcg gcgttcacgc ccgtcaggta
    29401 gccgcgcgtc ggccataacg cgctgtcggt tttgttgcgc ccccagccga cggtaccttt
    29461 gtacagccag cctttgaagc tgccgtctgt gccgtcggtt ttgccgtatt gtttgataaa
    29521 gtcggcatag tgtttgggcg ctttgttgta ggtgttgacg gtcaggtgtt ctgccaccaa
    29581 accgaaattc acgcggtcgt attcggtaac aggcacgctc atgcggatgc ctgcgcctgc
    29641 cgtggtggtt ttatattgtt tgatgctggt cgatgctttg cgcgggtcga aggcttttcc
    29701 gtaaacatcg tagcccaggc tgaccccgtc tgccgtgaag tacgggtcgg taaacgacag
    29761 cgagccgttg agcgtggttt tgcttcgtga ggcgcgcagg gcggccgact tgcccgtacc
    29821 gaacaggttg tcttgggaaa cgcctgcgga catgaccagg ccggtatcct gtacccaacc
    29881 cgcgctcaaa tccagggaac cggtggaacg ttcggtcagg ctcatgttca aatcgacttt
    29941 gtcgggcgtg ccggcaagcg ggacggcgtc aaactggaca ttgtcgaagt agcccaaaag
    30001 ctcgacgcgc tctttggagc gttgcagctt ggaggtgtcg taaggcgcgg attccatttg
    30061 gcgcaattcg cggcgcacga cttcgtcgcg ggttttgttg ttgccggtga tgtggatttc
    30121 gttgacgtag attttccggc ccggttcgat gtgcaggacg aaatcgacgg ttttggtttc
    30181 ggcgtttggc agcggctgta cgctgatttc gctgtatgcg tagcctgccg agcccatgcg
    30241 gttctgaatc tcacccaaaa cggcggtcat ctgctggcgt tcgtaccatt tgccgggctt
    30301 catggtcagc agtttttcca gttcggcttt ggggacttcg ttggtgtcgc cttcgatgga
    30361 gactttgccc caacggaaac gtccgccttc gtggacggtg attttgatgg tctgcttggt
    30421 tttgtcttcg ttggtttgga tgtcggtatc gaggatgcgg aaatcgaagt agccgttgtt
    30481 ctggtagaag tcggttactt tttccatgtc ttgggcaaat ttctgctcgt tgaattggtt
    30541 gcttcgtgtc agccatgtcc aaatgccgcc ttcggtcagc gacatctgcc gcatcagttt
    30601 gcggtcggaa tagacttggt tgccttcaaa ttcgatgtcg gtgattttgg cggatttgcc
    30661 ctcgtcaatc gtgatgtcga tgtcgacgcg gttgcgggcg agtttggtta ctttgggcgt
    30721 gatttggata ttgagtttgc cgcgcccgag gtattcttct ttcaggccgg cgactgcctg
    30781 attgagtgtc gcctgattaa agtattgcga ctgcgccagc ccgaacgatt cgaggttttt
    30841 cttaatggcg tcgttttgca gcatttttgc gccggtgatg ttgagcgagc cgatggtggg
    30901 gcgttcgata acggtcagca ggagctgccc gtccgcagtt tcgacgcgta cgtcgtcaaa
    30961 gaaaccggtg gcgtacaggc ttttgatgat ggtactgccg tgtgtgtcgt tgtaggtgtc
    31021 gccgactttg acgggcaggt agttgaatac ggtactcggc tcggtacgct gcaagccttc
    31081 gacgcggatg tcttggatgg tgaagtcggc aagtgccaaa ggcgatatgc ccaagaccat
    31141 cagtgcggaa gcaatctgtt tcagtttcat tgtcagttcc ttgtggtgcg gaatgcggtt
    31201 tcagacggca ttccgaaacg taaaatctaa ccgagcagcc gggtaacgtc gttgaagaag
    31261 gcgaccgcca tcatcagcat catcagggcg agcccgaagc gcaaaccgat gttttggacg
    31321 cgttcgccca aaggtttgcc gcgtatccat tcggcagtat aaaacacgag gtggccgccg
    31381 tccaaaacgg ggacgggcag caggttcagc acgccgaggc tgatgctgac cagtgccaaa
    31441 aattccaaat aactttgcaa gccgagttcg gcggactgtc cggcaatgtc ggcaatggtc
    31501 agcggcccgg aaatatggct gacggaggcg ttgccgctga ttagtttgcc gaaaaatttg
    31561 agggttgtcc acgagtggga aacggttttt tcccagccca tgccgaatgc gcggataaca
    31621 gacggacggt agctgcggcg gatttgcgcg tcccacgccc tgtccggctg cggacggagg
    31681 ccgacgcgcc cgatcagggt gtggtcgggc tgttcgacag tatcggggcg gatgtcggcg
    31741 gtatgggttt gtccggcgcg ttcgtaggtt aaggcaattt tcctgcccgg gctttggcgg
    31801 gtcaggtttg cccattcttg ccatgaggta atgggtttgc cgtcggcggc agtcagcctg
    31861 tcgcccggtt tcaggcctgc tttttcggcg gggctgcctt tttccacgcc accggcaacg
    31921 gttgtgattt taaagggcat cagtccgatg tagccttggt tttttgcgat tttaccggct
    31981 tccggcgtgc ctgcggcatc gatggtgcgg acggtttgcg cgcccgatgc cgtctgaacg
    32041 ccgacggcga ctttgccggc ttcgaggttg aggacgattt cggtttgcgc gctgccccaa
    32101 tctgcaacgg gtgtgccgtt gacggattgt attttgtcgc cgctttggaa gccggcgcgg
    32161 gcggcaatgg tgtcgggttc gactgtgccg acgtaggggc gcagttcggt tacgccgaag
    32221 gaaaagctca gtccgtacag caaaaccgcc agtgcgaggt tggtcagcgg gccggcggcg
    32281 acgatggcga tgcgtttggc ggggtgttgt ttgtcaaaag cgtagggtaa atcggcttct
    32341 gatacttcgc cttcgcgcgt gtcgaccatt ttgacgtaac cgcccaacgg aatcggggcg
    32401 aggcaccatt cggtgtcgcc gcgctttcgg gtgaaaaacg gtttgccgaa gccgacggaa
    32461 aagcgtacga ctttgacgcc gcacaatctg gcaacgatgt agtgtccgaa ctcgtgcagg
    32521 ctgaccaaaa tcaggatggc gaagataaaa gctagaaggg tgtgcaaatg gttttccttt
    32581 gataacggtg ttcagacggc atcagcgcag tgtgccgata aatgcccgcg cttgtgcgcg
    32641 tgtccgggca tcttgcgcca agagcccccc tatgtcgcct atgccgtctg aaaagtcttg
    32701 tgaaagacaa tgggcgacgg ttttggcaat gtcggtaaac ttaatctgtc cgtccaaaaa
    32761 ggcggcgacg gcggcttcgt tggcggcgtt caatacgcag ggcgcggctc cgcctgcgtt
    32821 catggcttca taggcgagct tcaggcaggg gaagcggtca aagtcgggct tttggaaggt
    32881 cagcgcggac aatgcgtcga aatccaggtc gccgacaccc gaatcgatgc gctcgggcaa
    32941 acccaaacaa taagcgatgg gcgttcgcat atcgggattg cccagttgcg ccagcacgga
    33001 gccgtcgcgg tagcgcacca tgctgtgtat cacggattgc ggatggatga cgacttcgag
    33061 tttgtcgggc ggacagttga acagccaatg cgcttcaatc agctccaaac ctttgttcat
    33121 catggtggcg gaatcgacgg agattttgcg tcccatacgc caattggggt gtttgaccgc
    33181 ttggtcgggc gtaatgctgt cgaacgtgtt taaatcggcg gtcagaaacg ggccgccgga
    33241 agcggtcagg ataatcgaag cgatgccgtg ttcgttcaga cggccggcgt aatcgcgcgg
    33301 caaaacttgg aaaacggcgt tgtgttcgct gtcgacgggc agcactgccg cgccgtttgc
    33361 acgggcggtt tccataaaca acgcgccgga aaccaccagc gtttctttgt ttgccagata
    33421 aatggttttg cctttttgcg ccgctgcgag cgcggaaggc agccccactg ccccgacgat
    33481 ggcgcacatg acaccgctga cttcgtcggc agacgcaacg tcaaccaatg cctgcgcgcc
    33541 gtgtaaaacc tgcgtcgccg tgccgtcgcg tttcaacagg gcttcaagcc gggcggcgtg
    33601 ttccgcatcg gcaacgacgg catattcggg gcggaacgtt tgacattgag ccgccaattt
    33661 ctcgacctgc ttatgccctg ccagcgcgaa tacgcggaat ttttcggggt ggcgggagac
    33721 aacgtccagc gtgctttcgc ctatgctgcc ggtactgcct aatatggtca ggacttgtgg
    33781 tgtcataatg gggataactt tataccggat gccgtctgaa gcgttttcag acggcataga
    33841 atcaatttaa aaccgacatc atcgccgcat agacgctgat aacggcaatc aggctgtcgg
    33901 tacggtcgaa cacgccgccg tgtccgggca gcaggttgct gctgtctttg atgcctgccg
    33961 cgcgcttgag ccagctttcc aaaaggtcgc cgcatacgct gacaacggtc aacaccaaac
    34021 cgattaacac ggtatcgaac cagcctgtat cgaatgccag ccagccggca cttcgtacgg
    34081 cggtcatgta cacggccacg caaaccgcgc cgccgattgc accttcccag cttttgccgg
    34141 ggctgattgc cggtgcgatt ttgtgtttgc cgaacgcctt gccgctgaaa tacgcgcaaa
    34201 tatcggcaac ccacaccaaa cccatcacgg cgagcagcgg cagggcatca tcgggatgcg
    34261 ggcgcaggga tacgagcgcg aaccaaaacg gcatgaccag aagccagccg acggcataaa
    34321 cctgccaacc gccgttgagc ctccatttga atctcaacca taaaggcata acggcgagcc
    34381 aaaatgccaa aacaacatac caaaccaaat taggcagcat ccagccgccc gcataggcaa
    34441 ccacgccgaa aaccaaggtt gcggcgaggt aatggttggt tttaattttg cacaaaccgc
    34501 ccatacgggc atattcccac aaggcaatca gggcaatcag tccgcaaaat gcagcccaca
    34561 accattgcgg cgcgtaaaac agcatgccca gcatcagcgg cagcagccac atggcggtta
    34621 ttacccgttg tttcagcata ttcagttcct ttgctgttcg ataggcagtt gctcggaggt
    34681 gcgtccgaac cgccgttcgc gtttttggaa cgaagcgacg gcggcatcta aggcggtttc
    34741 gtcgaaatca ggccacagga tgtcggtgaa atacagttct gcatacgcca tctgccagag
    34801 caggaaattg ctgatgcgcg tttctccgcc ggtgcggatg aacaaatccg gttccggtgc
    34861 attgcccagc atcaagtgtt tcgccagcgt gtcttccgta atctcggata cgccttcggc
    34921 aatcagtttg tttgccgcct gcaaaatatc ccatctgccg ccgtaatcgg cggcaatgct
    34981 cagggtcaga ccggtattgt ttgccgtcaa cgcctccgcc tcttcgatgc ccttcaggat
    35041 ttgacggctg aagcgttcgc ggctgcccag tattttcagg cgcatattgt tttcgtgcag
    35101 gcggcgtacc tgtttttgca aagcctgtaa aaacagcccc atcaggaacg aaacttcgtc
    35161 ttcggggcgg cgccagtttt cggttgaaaa ggcaaacacg gtcagatatt gcacacccag
    35221 tttggcgcaa tgcttcacca tattttccaa tgcgtccaaa ccgcgtttgt gtcccattat
    35281 gcgcgggagg aaacgttttt tcgcccaacg gccgttgccg tccataatca cggcgatatg
    35341 cttgggaatg gcggtgtgtt ccaaaacggc ctgcgtgctg cttttcatgt ctgcctttcg
    35401 cggttcggca ttcaaatgcc gtctgaacgc cgaaccgtgc aggttaaatt gccatcaaat
    35461 cttcttcttt ggtagtcagg agtttgtcgg cttcggtaat gtatttgtcg gtcagttttt
    35521 gaaccgcttc ttcgccgcga cgtgcctcgt cttcggaaat ttctttgtct ttgaggagtt
    35581 ttttgatgtg gtcgttggca tcgcggcgca cgttgcggat agagacgcgg ccttcttccg
    35641 cttcgccgcg tacgacttta atcaggtctt tgcggcgttc ctcggtcagc atgggcatcg
    35701 gcacgcggat caggtcgccg acagctgccg ggttcagtcc caagtttgaa tcgcggatgg
    35761 ctttctcgac tttggccgcc atattgccct caaacggttt cacgccgatg gtgcgcgcgt
    35821 ccagaagcgt tacgttggca acttggctga cggggaccat gctgccccag tattcgactt
    35881 ccacttggtc gagcaggccg gtatgcgcgc ggccggtacg cactttcgcc agattttctt
    35941 tcagtacttc gaccgaacgc tgcatcttgc cttcggctgt tttttgaata tcgttgatca
    36001 tattgttctt tcggtgggat aaggtgggcg ggagaccgtc tgaacgcgtt tcaagccgtt
    36061 cagacggcat aaagaccgtt aaccgcgaat agtaccgtta ttcgggcata acgacaaggt
    36121 aggcggattg gggatgccgt ctgaagcgac aggcgtttca gacggcatcg tgtccggccg
    36181 tcagccgtgt tcccgtgttt caagcaggct ttggcgcagg tgttggcgtt cgtgggcatt
    36241 cagccatttg cggcgggtgc gttgcagcag gatgacgagg gcagaaattt cctgacgcat
    36301 attggtgctg agccagagga agccctgcca ttggtagtgg aggtgttcgg cgagggcttc
    36361 cagttcgggg ttgatggcgg tgtcgatgcg gatgcggcgt gcgtgcctgc cgttgatgag
    36421 ggcgacggtt tgttgcaggt cggtttggag ttgggtgaag tggcggtcga gcagccggat
    36481 ttcgctgccg ttgagtttgg gagattgcag cttggcggca gtggtcagga gcagctcggt
    36541 ggtgttgaca attttacggt gggcgtgctg catggcttcc atcatggcgg ggctgatgcg
    36601 gctttcgccc gatgtggcgg cgaggtggct gcggcttttg accatgcgtg cgttgatttg
    36661 gcgcattttc gccatgttct cttcgaggcg ttcgcgggtc atgcgcctgc cgttgctgat
    36721 ttcggcaatc attttgctgc agtcggtcag gttgtcggca agcatgaaac gccacatcag
    36781 tgtggatttc agcggcagca gtttggcggc ggcgatggcg atggccgcgc cgatgaggac
    36841 gttcatcgcg cgcatcaggc cgctgtcgaa ccattcgctg ccgttgtcgc cgatgagcat
    36901 gcacatcgtc agccccgcca gcatagggac gtagccgttt ttgccgaccg ccgcccagcc
    36961 ggccagtgcg cttgccgtgc cgacggtgag gtagaagagg aggttgccgt ggaaataatg
    37021 ctggttcagc cataaaacgc ccaaacccgc gcccagcccg atgaccgtgc cgagcatacg
    37081 ttccaccgcc ttggagtaaa tcgccccttg aaactggagc atgccgagga cgacgaagac
    37141 ggtcatccct atccattcgc cgtgttggag gtggaacagc cgggcgagtg cggtggcgaa
    37201 caggacggct ccgccaagcc ggacggagtg gatgaggcgg cggtagcggt agcgttcgta
    37261 ggagttgagc cagcggctgg aaaggcggtt gcgttgcgag gtgttcatat cggttgccgt
    37321 ctgaagcgga aatgtgaaaa agcacaggct tcctgggata gggagggtct gtgcttggta
    37381 ttggtgccgg agaagggaat cgaacccccg accttcgcgt tacgaatgcg ctgctctacc
    37441 gactgagcta caccggcttt tttcgttatg atatatatga acggttgttt ctgcaacttt
    37501 tcgggctgct ggcaaagttt tgcacggtat aatgcggttt gcttcgtgag gagagtcggt
    37561 gatgtatgtg aacgagaaat atccctatgc ggctttgttt gcggggctgg tgtttttgac
    37621 gctgccgttc gcactgtcgg tgcatgatgc cttggcattt gcgttcggac ggacggggct
    37681 gctggtgtcg gtgtcggacg gcggattcgg ctggcgtggc ggttgggaca gcactgtttg
    37741 gtttgtgttc ggtgtgtttg cgtttttgaa tgtggttgtg tcggcgggtc tgacgaaact
    37801 ggcgtacaaa aagatgatgc ggcggcattc gcgttacgcg ctgtttctgt caggcgtggc
    37861 ggcttgcgcg gcggcggcgg tggcttggat tttcgaactg ttgttgggca gtgccgcctt
    37921 gggcgggctg cgcggggagg cggtgttgga atatgcgttt gccgtgtggc tggtggcgat
    37981 gctgacgctg cccaaacgct tgacgcgcgc gccagtgcag ctggtggtgt tccacaggaa
    38041 aaaataggac ggaacgggaa atgccgtctg aaacccgaca cgcggtttca gacggcatgt
    38101 ttttccgcta acattacgcc tgaatatgga taggaagcag atatggaacg taaagaacgc
    38161 ctacaatcgg gcattgctgc gatggggctg gatatttcgg aaacggcgca ggacaggctt
    38221 ttggcctatg tggatttgtt gaaaaagtgg aacaaaacct acaatctgac cgccctgcgc
    38281 gacgaggaaa aaatgattgt ccatcatctt ttggacagcc tgacgctgct gccctatatc
    38341 gaaggcgcac agacgatgct ggatgtcggt tcgggcggag gacagcccgg cattccggcg
    38401 gcggtgtgcc gtccggatgt gcagataacc cttttggatg cgaatacgaa gaaaacggct
    38461 tttttacagc aggcggttat cgagttggga ttggacaatg tgcgcgtggt atccggacgc
    38521 gtggaggcgg tttcggacgt gcgtgccgac gtgattacca gccgtgcgtt tgcagaactg
    38581 gcggattttg tgtcgtggac ggcgcatctg ttgaaagacg gcggctactg ggcggcgatg
    38641 aagggcgtgt atccgcaggg ggaaatcgac cacctgccgc aggatgtgtg cgtcgaaaaa
    38701 gtccaaaggc ttgacgtgcc gggcttggat gcggaacgcc atatcgtcat actccgcaag
    38761 cgttgagcgc acttcagacg gcatgaatac cttttttgtg cggataaagg taaaattccg
    38821 cactgttttt cttttttcaa catcagacgg gacacgggcg ggacatgagt gcgaacatcc
    38881 ttgccatcgc caatcagaag ggcggtgtgg gcaaaacgac gacgacggta aatttggcgg
    38941 cttcgctggc atcgcgcggc aaacgcgtgc tggtggttga tttggatccg cagggcaatg
    39001 cgacgacggg cagcggtatc gacaaggcgg gtttgcagtc cggcgtttat caggtcttat
    39061 tgggcgatgc ggacgtgaaa tcggcgacgg tacgcagcaa agagggcgga tacgctgtgt
    39121 tgggtgcgaa ccgcgcgctg gccggtgcgg aaatcgagct ggtgcaggaa atcgcccggg
    39181 aagtgcgttt gaaaaacgca ctcaaggcag tggcggaaga ttacgacttt atcctgatcg
    39241 actgtccgcc ttcgctgacg ctgttgacgc ttaacggctt ggtggcggcg ggcggcgtga
    39301 ttgtgccgat gttgtgcgaa tattacgcgc tggaagggat ttccgatttg attgcaaccg
    39361 tgcgcaaaat ccgtcaggcg gtcaatcccg atttggacat cacgggcatc gtgcgcacga
    39421 tgtacgacag ccgcagcagg ctggttgccg aagtcagcga acagttgcgc agccatttcg
    39481 gggatttgct ttttgaaacc gccatcccgc gcaatatccg tcttgcggaa gccccgagcc
    39541 acggtatgcc ggttatggct tacgacgcgc aggcaaaggg taccaaggcg tatcttgcct
    39601 tggcggacga gctgatggcg agggtgtcgg ggaaataggt caatccaaat cgggctgccc
    39661 gtgcctttat gctgtttggc cgagtgcgtt aatatggcgg attaaaataa aaatacttat
    39721 atcgtcattt atagtggatt aacaaaaacc agtacggcgt tgcctcgcct tagctcaaag
    39781 agaacgattc tctaaggtgc tgaagcacca agtgaatcgg ttccgtacta tctgtactgt
    39841 ctgcggcttc gtcgccttgt cctgattttt gt
//
LOCUS       DAXIDM010000007        34029 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000007 DAXIDM010000000
VERSION     DAXIDM010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 34029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34029
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.007"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(91..450)
                     /gene="rnpB"
                     /locus_tag="ACFOAE_000278"
     ncRNA           complement(91..450)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACFOAE_000278"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(529..1632)
                     /gene="prfB"
                     /locus_tag="ACFOAE_000279"
     CDS             complement(529..1632)
                     /gene="prfB"
                     /locus_tag="ACFOAE_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFC6883850.1"
                     /translation="MEAEVINQLNNTLNDLEKRSEDIRVYMDYQGKKDRLEEVVGLSE
                     DPELWNDPKRAQEIGKERKILEGIVLTLDNIASGIEDNRMLIEMTVEENDEEGFAAVQ
                     EDVAGLEKQMADLEFKRMFNQPADPNNCFIDITAGAGGTEAEDWAGMLFRMYSRYAER
                     KGFKIEILEEDDGEIAGINRATIRVEGEYAYGLLRTETGVHRLVRYSPFDSNNKRHTS
                     FASVFVYPEIDDSIEIEINPADLRIDTYRASGAGGQHINKTDSAVRITHEPTGIVVQC
                     QNDRSQHANKAAAMEMLKSKLYELEMRKRNEEKQALEEGKSDVGWGSQIRSYVLDSSR
                     IKDLRTGYEVGNTKAVLDGDLDGFIEASLKQGV"
     gene            complement(1735..2628)
                     /locus_tag="ACFOAE_000280"
     CDS             complement(1735..2628)
                     /locus_tag="ACFOAE_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFC6883851.1"
                     /translation="MVTFSKIRPLLAIAAAALLAACGTAGNNAARKPVQTAKPAAVVG
                     LALGGGASKGFAHVGIIKVLKENGIPVKVVTGTSAGSIVGSLFASGMSPDRLELEAEI
                     LGKTDLVDLTLSTSGFIKGEKLQNYINRKVGGRRIQQFPIKFAAVATDFETGKAVAFN
                     QGNAGQAVRASAAIPNVFQPVIIGRHTYVDGGLSQPVPVSAARRQGANFVIAVDISAR
                     PGKNISQGFFSYLDQTLNVMSVSALQNELGQADVVIKPQVLDLGAVGGFDQKKRAIRL
                     GEEAARAALPEIKRKLAAYRY"
     gene            2970..3419
                     /locus_tag="ACFOAE_000281"
     CDS             2970..3419
                     /locus_tag="ACFOAE_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HFC6883852.1"
                     /translation="MKIGTTWQTASAMLVLRLFAAYEFLESGLQKWNGENWFSEINDQ
                     FPFPFNLLPDALNWNLAMYAELLLPVLLLLGLATRLSALGLMVVTAVAWAAVHAGSGY
                     NVCDNGYKMALIYIVVLIPLLFQGAGGWSLDTLLKKRFCPQCRLKQD"
     gene            3493..3801
                     /locus_tag="ACFOAE_000282"
     CDS             3493..3801
                     /locus_tag="ACFOAE_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883853.1"
                     /translation="MNKNIAAALAGALSLSLAAGAVAANKPASNATGVHKSAHGSCGA
                     SKSAEGSCGAAGSKAGEGKCGEGKCGATVKKTHKHTKASKAKAKSAEGKCGEGKCGSK
                     "
     gene            3917..4759
                     /locus_tag="ACFOAE_000283"
     CDS             3917..4759
                     /locus_tag="ACFOAE_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF692 domain-containing protein"
                     /protein_id="HFC6883854.1"
                     /translation="MIQHAGLGYRRDLAEDFLSLSENSPICFIEAAPENWLKMGGWAR
                     KQFDRVAERLPLALHGLSMSLGGQAPLDTDLIDGIKEMMRRYDCTFFSDHLSYCHDGG
                     HLYDLLPLPFTEEMVHHTARRIREVQDRLGCRIAVENTSYYLHSPLAEMNEVEFLNAV
                     AREADCGIHLDVNNIYVNAVNHGLLSPEAFLENVDAERVCYIHIAGHDVETPELLIDT
                     HGAAVLPTVWDLLELAYAKLPTIPPTLLERDFNFPPFAELEAEVAKIADYQTRAGKEC
                     RRAA"
     gene            4749..5495
                     /locus_tag="ACFOAE_000284"
     CDS             4749..5495
                     /locus_tag="ACFOAE_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2063 domain-containing protein"
                     /protein_id="HFC6883855.1"
                     /translation="MQPETSAQYQHRFAQAIRGGEAADGLPQDRLNVYIRLIRNNIHS
                     FIDRCYTETRQYFDSEEWSRLKEGFVRDAHAQTPYFQEIPGEFLQYCQSLPLSDGILA
                     LMDFEYTQLLAEVAQIPDIPDIHYSNDSKYTPSPAAFIRQYRYDVTDDLHEAETALLI
                     WRNAEDDVMYQTLDSFDMMLLEIMGSSALSFDTLAQTLVEFMPEDDNWKNILLGKWSG
                     WTEQRIIIPSLSAISENMEGNSPGQNHLSA"
     gene            5517..6104
                     /locus_tag="ACFOAE_000285"
     CDS             5517..6104
                     /locus_tag="ACFOAE_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFC6883856.1"
                     /translation="MPLPDLTDAELIESRKLLLHFARLQLPDHPDLAEDLVQETLLSA
                     YSAGDNFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTTLDDELLDEAFESHFSQN
                     GHWTPEGQPQHWNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQ
                     MCGISTSNYHTIMHRARESLRQCLQIKWFNQENPK"
     gene            6110..6289
                     /locus_tag="ACFOAE_000286"
     CDS             6110..6289
                     /locus_tag="ACFOAE_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HFC6883857.1"
                     /translation="MKKCRDITLLLSKHQDRETTPGEKISIYTHLLFCPYCREYKRQL
                     QTIKRSLAKTTRTSK"
     gene            6521..6961
                     /locus_tag="ACFOAE_000287"
     CDS             6521..6961
                     /locus_tag="ACFOAE_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-adhesin E family protein"
                     /protein_id="HFC6883858.1"
                     /translation="MIKETLMRPIFLSFVLLPILITACSTPDKSARWENIGTISNGNI
                     HTYINKDSVRKNGNLMIFQDKKVVTNLKQERFANTPAYKTAIAEWEIHCNNKTYRLSS
                     LQLFDTKNTEISTQNYTASSLRPMSILSGTLTEKQYETVCGKKL"
     gene            complement(7218..7565)
                     /locus_tag="ACFOAE_000288"
                     /pseudo
     CDS             complement(7218..7565)
                     /locus_tag="ACFOAE_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467771.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7593..8195)
                     /locus_tag="ACFOAE_000289"
     CDS             complement(7593..8195)
                     /locus_tag="ACFOAE_000289"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFC6883859.1"
                     /translation="MTDVLQTVFYIMLFPRIIAASAQRKLSVYLKKGGLVAYPTESCY
                     GLGCLPTLAKALGKLAHLKKRPQHKGMIVIGNQFEQLQPLLQMPSENLQDMLRKEWPA
                     PKTFLLSAKSCVLPELRGKQRSKLAVRVPAHVGARRLCQALQTPLVSTSCNRAGKRAC
                     RTEREVRRQFGRDVWIVGGRIGRQKSPSQIIDGKTGKRLR"
     gene            complement(8229..9500)
                     /gene="purD"
                     /locus_tag="ACFOAE_000290"
     CDS             complement(8229..9500)
                     /gene="purD"
                     /locus_tag="ACFOAE_000290"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFC6883860.1"
                     /translation="MKLLVIGNGGREHALAWKLAQSPKVETVFVASGNAGTAIEPKLQ
                     NIDLTAHQDLIEFCRKENIVFTVVGPEAPLAAGVVDDFRAAGLKIFGPTQYAAQLESS
                     KDFAKAFMAKYNIPTAQYQTFENADAAHDYVNQKGAPIVIKADGLAAGKGVIVAMTLD
                     EAHAAIDDMLLDNKMGNAGARIVIEDFLQGEEASFIVMVDGNNVLPMATSQDHKRLLD
                     GDKGLNTGGMGAYSPAPVVTPVVYERAMNEIILPTVAGMKAEGHEFTGFLYAGLMIDQ
                     SGAPHTIEFNCRFGDPETQPIMSRLNSDLSDLVEAAIDGKLDSVTAEWSPQTAVGVVL
                     AAQNYPETPKKGDVISGLDAANQVGKVFHAGTTANEKGDVLTNGGRVLCVVGLGDNVA
                     QAKAKAYGALEKISFDGMQYRKDIADKAINR"
     gene            9658..9975
                     /locus_tag="ACFOAE_000291"
     CDS             9658..9975
                     /locus_tag="ACFOAE_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4298 domain-containing protein"
                     /protein_id="HFC6883861.1"
                     /translation="MQKRIDEIQSKYREWCHLLPQLEEDIRRWKHAVALIRDMDNFYT
                     HEYQACHRAIEDGAEVDLRTEGEYSIMSEDALWNALGEFHQLAWLYLRSSVDALDKYT
                     QED"
     gene            complement(10027..10638)
                     /locus_tag="ACFOAE_000292"
     CDS             complement(10027..10638)
                     /locus_tag="ACFOAE_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFC6883862.1"
                     /translation="MITTYKTITSSTQAEFKDKGSRFIAFAYPIRTLADVKKYLDPLK
                     EEHHKARHWCYAYRLGVDGMQFRANDDGEPSGSAGRPILGQIDSVGITDVLVVVVRYF
                     GGTLLGVPGLIHAYKEATAQALAVAEVVEKNIEKTVWLKCEYPFLNEAIRIAKQYQAD
                     VLERDLQLDCRLTVSLSLVNYEACVAAWKSTRQIEVNTEKPFE"
     gene            complement(10701..11636)
                     /locus_tag="ACFOAE_000293"
     CDS             complement(10701..11636)
                     /locus_tag="ACFOAE_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HFC6883863.1"
                     /translation="MSVLIIVEHDNKQLNPTTLHAVTAAAKLGKIDLLVAGSGASAVV
                     EFAKQVAGVEKVLVADAAHYAEGLAEELAPLVVKLAADYCYVAATATTFGKNLLPRVA
                     ALLDVPQISDLTEIVDNTTFVRPIYAGNAFETVQADSEKLVLTFRATVFDAVAAQGGN
                     AEVINVEATPAQNLSRFVNRQLSHSDRPELTQAKVIVSGGRALGSAEKFNEVLTPLAD
                     VLGAAIGASRAAVDAEYAPNDAQVGQTGKVVAPQLYFAIGISGAIQHVAGMQDSKVIV
                     AINKDADAPIFNVADYGLVGDLFEIVPQLTEVLKN"
     gene            complement(11647..12396)
                     /locus_tag="ACFOAE_000294"
     CDS             complement(11647..12396)
                     /locus_tag="ACFOAE_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EtfB protein"
                     /protein_id="HFC6883864.1"
                     /translation="MKALVAVKRVVDYNVKVRVKADGSDVDIGNVKMSMNPFDEIAVE
                     EAVRLKEAGKVSEIVAVSLGEKKCEETLRTALAMGADRAIHVETDTKLESLAVAKLLK
                     AVADKENPQIFFLGKQAIDDDANQVAQMLAALLNAAQGTFASKVHIEGGEVQIVREID
                     GGEETIALKLPAVISADLRLNEPRFVKLPNIMAAKKKPLEKLTPDDLVADISPRLKTV
                     KFAEPKARQVGVKVASVAELVEKLKNEAKVI"
     gene            complement(12623..13591)
                     /gene="waaC"
                     /locus_tag="ACFOAE_000295"
     CDS             complement(12623..13591)
                     /gene="waaC"
                     /locus_tag="ACFOAE_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008920 - lipopolysaccharide
                     heptosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase I"
                     /protein_id="HFC6883865.1"
                     /translation="MKILLVRLSSMGDLIHTLPAIEDLARQCPDVELHWLCEAGFADI
                     ARLHPFVKKIHVMKWRQWRKHLFQAETWREMGHLKQTLRQEAFNFVLDSQGLIKSACF
                     AKMAKSPIYGLDKNSAREGLAALAYAKTYAVPKGKNAVWRNRELFAQVFGYAMPETQV
                     FGLTVPEAGRLKNLAQPYYAALHATSRDSKLWPVENWRSLLQKLNEEQQCNIYLPWGN
                     EDEKTRAKQIADGLPFAIVCDKMNLLQAAYLLKHAVGIVGVDTGLLHLANALEKPVVG
                     IYTDTDPIKTGVQVSPIAKNLGNIGQIPTADLVYQALMDCVAADKG"
     gene            complement(13628..14263)
                     /locus_tag="ACFOAE_000296"
     CDS             complement(13628..14263)
                     /locus_tag="ACFOAE_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamidase"
                     /protein_id="HFC6883866.1"
                     /translation="MIVSIDVDAQKTFTPLCPKELPVNEGHLIVEELNAQAALADLRV
                     MTKDAHHMVAKWLVDNPVDMLKPTGLPDADLTWVAHAMVGTRGYELLDGLPSAKEYDY
                     CVWKGVDPELHPYGACFHDIEEKLSTGLIEWLRCQNTDMVIVGGLATDYCVKTTVLQL
                     LKGSNWQVIVNEAACRGIAPDTIETAWQEMRSAGAVILKNAEEIKKYINNQ"
     gene            14378..15058
                     /gene="tsaA"
                     /locus_tag="ACFOAE_000297"
     CDS             14378..15058
                     /gene="tsaA"
                     /locus_tag="ACFOAE_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HFC6883867.1"
                     /translation="MTYTIVPIATARSPYKQKFGIARQPGLVSAAEVCIELNPEFTAD
                     SVRGLEDFDYVWISFIFHGVLDEGWAQMVRPPRLGGKQKMGVFATRSPHRPNHLGLSL
                     LKLNRIETGKPVRLYCSGADLLDGTPIVDIKPYIPFVESKPDAASGFVSGKPVELEVV
                     WQENIGAENLSANTKNLISQSIAQDPRPAYQNIPERIYVMNIADYEIRFQIEENRATV
                     IDLSPTPL"
     gene            15127..15246
                     /locus_tag="ACFOAE_000298"
                     /pseudo
     CDS             15127..15246
                     /locus_tag="ACFOAE_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(15316..16320)
                     /gene="gap"
                     /locus_tag="ACFOAE_000299"
     CDS             complement(15316..16320)
                     /gene="gap"
                     /locus_tag="ACFOAE_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003766473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFC6883868.1"
                     /translation="MSIKVAINGFGRIGRLTLRQIEKAHGIEVVAVNDLTPAEMLLHL
                     FKYDSTQGRFQGTAELKDDAIVVNGKEIKVFANPNPEELPWGELGVDVVLECTGFFTN
                     KTKAEAHIRAGARKVVISAPGGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMA
                     AVLQKEFGVVEGLMTTIHAYTGDQNTLDAPHRKGDLRRARAAALNIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPVATGSLTELVSVLERPVTKEEINAAMKAAASESYGYNEDQ
                     IVSSDVVGIEYGSLFDATQTRVMTVGGKQLVKTVAWYDNEMSYTCQLVRTLEYFAGKI
                     "
     gene            16764..19358
                     /gene="mutS"
                     /locus_tag="ACFOAE_000300"
     CDS             16764..19358
                     /gene="mutS"
                     /locus_tag="ACFOAE_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFC6883869.1"
                     /translation="MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAA
                     KLLDITLTTRGQVDGEPVKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPV
                     ERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDK
                     LDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRG
                     FGLDGKEHAVAIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEIT
                     QTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRARQEAVAALESQYKPL
                     QCRLKSIADIERIAARIAVGNARPRDLAALRDSLFALSEIELSAECSSLLGTLKAVFP
                     ENLSTAEQLRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERE
                     RTGLSTLKVEFNRVHGFYIELSKTQAEQAHADYQRRQTLKNAERFITPELKAFEDKVL
                     TAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEF
                     ADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIV
                     LLAHTGCFVPADAATIGPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSL
                     VLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFATHYFELTYLPETHAAAVNMHL
                     SALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNELEDQAAANRP
                     QLDIFSTMPSEKGDEPNVDSFVDKAEEKHFEGILAAALEKLDPDRLTPREALSELYRL
                     KDLCKSVS"
     gene            complement(19482..19973)
                     /locus_tag="ACFOAE_000301"
     CDS             complement(19482..19973)
                     /locus_tag="ACFOAE_000301"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC6883870.1"
                     /translation="MNSLFVDNTVFITRLKAGHIGRLVQALFEEWHGFEPWSSVDKIR
                     AYYGRCLKDDELPLAFAAVDDSGTLLGSATVKRHDMESFPQYEYWLGDVFVLPEYRGK
                     GIGRRLVAHCIGAARSLGIKFLYLYTPDVQIFYESFGWAVVGRHFHNGEWVTVMRLDV
                     DKV"
     gene            complement(19977..20372)
                     /locus_tag="ACFOAE_000302"
     CDS             complement(19977..20372)
                     /locus_tag="ACFOAE_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883871.1"
                     /translation="MPSDVGMRLQTAFKRKLNMKKIFYFLMVVFSTSVWAGDAEDNLL
                     SIQSGYRALLQKQNKLDGKIIGMQSDLEDARRRLQAAQADIARLEAEIPAAMAQKARQ
                     AEELRQIGVRLDHAWNAVYGAGGTKASGN"
     gene            complement(20393..21787)
                     /gene="gltX"
                     /locus_tag="ACFOAE_000303"
     CDS             complement(20393..21787)
                     /gene="gltX"
                     /locus_tag="ACFOAE_000303"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFC6883872.1"
                     /translation="MTVKTRFAPSPTGYLHIGGVRTALFSWAFARHHKGEFLLRIEDT
                     DLARSTAESVNIILDGMKWVGLDYDNADNVVYQTRRFDRYKEVIAELLAKGDAYYCYC
                     SKEELEAMREKAEKEGTATYDRRWRPEAGKTLPEIPADVQPVVRFKTPLDGVTQWTDL
                     VKGEISIPNEALDDLIIARADGTPTYNFCVVVDDYDMGVTHVIRGDDHVNNTPKQINI
                     LKAIGATLPEYGHLPMILNEQGKKISKRSGDTVAITDFGAMGILPEAMLNYLARLGWA
                     HGDDEFFTMEQFIEWFDLKDVSPSPSRMDLKKLYWINGEHIKITPNGKLAELVKPRLA
                     LRDIHETEKPALEDVLAQVKDRAQDLNALADECLYFYKKQVPAEADVAKHWDDEAAAR
                     MLRFAERLEGLEDWNTEAIHDLFKPFCDEEGIKMGKLGMPLRLAVCGTAKTPSVDAVL
                     ALIGKEEVLKRIRA"
     gene            complement(21979..22635)
                     /locus_tag="ACFOAE_000304"
     CDS             complement(21979..22635)
                     /locus_tag="ACFOAE_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFC6883873.1"
                     /translation="MKKRLFCSRNGLRYYLLGGFCLSVFPLLMVFASSVWAVYRTGGQ
                     VLPPYVRADAALVLGAAAWDKHPSPVFRERINHAIALYQSRRVGKIVFTGGRTKKGYM
                     TEAEVGRRYALKQGVPARNILFENTSRNTYENLNNIRPVLRANGIASVVIVSDPYHLA
                     RAAEMAEDLGVRVYMSATPTTRFDAGNKKKIFMLQEGYALSLYRLEKWGWDFFNWLFH
                     "
     gene            complement(22632..22985)
                     /gene="arsC"
                     /locus_tag="ACFOAE_000305"
     CDS             complement(22632..22985)
                     /gene="arsC"
                     /locus_tag="ACFOAE_000305"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271974.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HFC6883874.1"
                     /translation="MSEIKIFHNPRCSKSRAALSLLEERGIAAEVVKYLDTPPDLSEL
                     KDIFNKLGLASARGMMRVKDDLYKELGLDNPDLDNDALLRAIADHPALLERPIVLANG
                     KAAVGRPLENIEAVL"
     gene            23109..23591
                     /locus_tag="ACFOAE_000306"
     CDS             23109..23591
                     /locus_tag="ACFOAE_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFC6883875.1"
                     /translation="MKYLNLAAITLAATFAAHTASADELAGWKDNTPQSLQSLKAPVR
                     IVNLWATWCGPCRKEMPAMSKWYKAQKKGSVDMVGIALDTSDNIGNFLKQTPVSYPIW
                     RYTGANSRNFMKTYGNTVGVLPFTVVEAPKCGYRQTITGEVNEKSLTEAVKLAHSKCR
                     "
     gene            23786..24436
                     /gene="ftsE"
                     /locus_tag="ACFOAE_000307"
     CDS             23786..24436
                     /gene="ftsE"
                     /locus_tag="ACFOAE_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFC6883876.1"
                     /translation="MIRFEQVSKTYPGGFEALKNVSFQINKGEMIFIAGHSGSGKSTV
                     LKLISGITKPSRGKILFNGQDLGTLSDNQIGFMRQHIGIVFQDHKILYDRNVLQNVIL
                     PLRIIGYPPRKAEERARIAIEKVGLKGRELDDPVTLSGGEQQRLCIARAVVHQPGLLI
                     ADEPSANLDRAYALDIMELFKTFHEAGTTVIVAAHDETLMADYGHRILRLSKGRLA"
     gene            24433..25350
                     /gene="ftsX"
                     /locus_tag="ACFOAE_000308"
     CDS             24433..25350
                     /gene="ftsX"
                     /locus_tag="ACFOAE_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFC6883877.1"
                     /translation="MSIIHYLSLHVESARTALKQLLRQPFGTLLTLIMLAVAMTLPLF
                     MYLGIQSGQSVLGKLNESPQITIYMETAAAQSDSDTVRSLLTRDKRLDNIRFISKEDG
                     LEELQSNLDQNLISMLDGNPLPDVFIVTPDLATTPAQMQAIYRDITKLPMVESANMDT
                     EWVQTLYQINEFIRKILWFLSLTLGMAFVLVAHNTIRLQILSRKEEIEITKLLGAPAS
                     FIRRPFLYQAMWQSILSAAVSLGLCGWLLSAVRPLVDAIFKPYGLNIGWRFFYPEEIV
                     LVFGFVIALGVFGAWLATTQHLLGFKAKK"
     gene            25441..25689
                     /locus_tag="ACFOAE_000309"
     CDS             25441..25689
                     /locus_tag="ACFOAE_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1990229 - iron-sulfur cluster assembly
                     complex [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HFC6883878.1"
                     /translation="MLTPEQVKAMIAGVAKCEHIEVEGDGHHFFAVIVSSEFEGKARL
                     ARHRLIKDGLKAQLESNELHALSISVAATPAEWAAKAQ"
     gene            complement(25755..26933)
                     /locus_tag="ACFOAE_000310"
     CDS             complement(25755..26933)
                     /locus_tag="ACFOAE_000310"
                     /EC_number="2.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFC6883879.1"
                     /translation="MAFLKLTEQNVQGKTVLIRADMNVPFKDGKISDDTRIRASLASI
                     KYCLDNGASVIVMTHLGRPTEGEFHSEDDVAPVAAHLGGLLGKDVKVLNDWRENKPAL
                     NAGDVVMLQNVRINKGEKKNDLELGKAYASLCDVFVNDAFGTAHRAQASTEAVAQAAP
                     VACAGVLMAGELDALGKALKQPARPMVAIVAGSKVSTKLTILESLADKVDQLIVGGGI
                     ANTFLLAEGKAIGKSLAEHDLVEESKKIMAKMAAKGGSVPLPTDVVVAKAFAADEEAV
                     VKDIADVAEDEMILDIGPKSAAALADLLKAAGTVVWNGPVGVFEFDQFAGGTKALAEA
                     IAQSKAFSIAGGGDTLAAIAKFGVTEQIGYISTGGGAFLEFLEGKELPAVAALEKRGE
                     "
     gene            complement(27014..28267)
                     /gene="murA"
                     /locus_tag="ACFOAE_000311"
     CDS             complement(27014..28267)
                     /gene="murA"
                     /locus_tag="ACFOAE_000311"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFC6883880.1"
                     /translation="MDKLKISANGPLNGEITVSGAKNAALPLMCAGLLTSGTLRLKNV
                     PMLADVKTTQKLLQGMGARVLTDNISEFEINGGTVNNTCAPYELVRTMRASILVLGPT
                     LARFGEAQVSLPGGCAIGSRPVDQHLKGLEAMGAEIVIEHGYVKAKGKLKGTRVAMDV
                     VTVGGTENLLMAATLAEGTTVLENCAIEPEVVDLAECLVKMGAKISGIGTSTMIVEGV
                     DELHGCEHSVVPDRIEAGTFLCAVAITGGRVVLRNAAPKTMEVVLDKLVEAGAVIEAG
                     DDWIAIDMRQRPKAVDIRTVVHPGFPTDMQAQFMALNAVAEGSCRVVETIFENRFMHV
                     PELNRMGANITTEGNTAFVQGVERLSGAVVKATDLRASASLVIAGLAARGETVVEQIY
                     HLDRGYENIEKKLGSVGAKIERVSG"
     gene            complement(28487..28562)
                     /locus_tag="ACFOAE_000312"
     tRNA            complement(28487..28562)
                     /locus_tag="ACFOAE_000312"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28527..28529),aa:Lys,seq:ttt)
     gene            complement(28631..29605)
                     /locus_tag="ACFOAE_000313"
     CDS             complement(28631..29605)
                     /locus_tag="ACFOAE_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HFC6883881.1"
                     /translation="MTEYPGIGSPLFYGVFFAAVLVMIALDMFSLKKNSSHKVGVKEA
                     LAWSGLWVAVSCLFAGWLYFKLAGNPGYGAAVAKEKVLEFFTGYILEKSLAVDNIFVF
                     LMIFGYFKVAPQFQHRVLLYGVLGALVLRTVMIFVGAALVQQFEWILYLFGAFLLYTG
                     IHMMKPEGDEEGDLANSRLLNAVKKVVPVGTEFHGEKFFTVENGKKIATPLFLVLVMI
                     ELSDVVFAVDSIPAVFAVTTDPFIVLTSNIFAILGLRAMYFLLADVAERFIFLKYGLA
                     FVLGFIGVKMLVMHWVHIPISVSLSVVFGALGASILTSLIYTKKQSDK"
     gene            complement(29638..30087)
                     /locus_tag="ACFOAE_000314"
     CDS             complement(29638..30087)
                     /locus_tag="ACFOAE_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family copper resistance protein"
                     /protein_id="HFC6883882.1"
                     /translation="MSIYAVAHIVHLYCAIAFVGGVFFEVLVLSVLHTGRVSCEARRE
                     VEKAMSYRAVRVMPFVVGLLFASGIVMAANRYLSILGEPFATSFGTMLTLKILLAFSV
                     LAHFAIAVVKMARSTLTVGWSKYIHTVVFTHMLLIVFLAKAMFYISW"
     gene            complement(30128..31399)
                     /gene="waaA"
                     /locus_tag="ACFOAE_000315"
     CDS             complement(30128..31399)
                     /gene="waaA"
                     /locus_tag="ACFOAE_000315"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HFC6883883.1"
                     /translation="MFQWLYDALWLLAPIWIRRYLDKRSGSAPAYRAHRDERFGKPYP
                     NPVTGAVWIHAVSVGETRAAQPLIRELRQRFPDAPLLMTQMTPTGRETAQVLFPDAQC
                     RYLPYDKKTWVRQFLREHRPMFGILMETEIWPNLMTECRKSGVPLFLANARLSEKSLN
                     GYLKVRRLIRPAAASLTGCLAQTEADAARLAKLGAASVQVCGNTKYDLMPSEQMKTLA
                     GQFEKRIGDRPVAVCGSTRVYRGEDEAEKLLAAWQQYRGDALLVVVPRHPEHFQTVFE
                     TAKRFGFKVQRRSDGLPVEPDTQVWIGDSMGELCAYYLCADVAFVGGSLVDSGCQNII
                     EPLSCGVPTIFGFSTYNFSEACRYALASGAAVQVESADAWRAAVEKALSSEGGGMQMQ
                     ARVDGFIAQHRGAGARIAEAVREAVCGHRGR"
     gene            complement(31462..32910)
                     /gene="gnd"
                     /locus_tag="ACFOAE_000316"
     CDS             complement(31462..32910)
                     /gene="gnd"
                     /locus_tag="ACFOAE_000316"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019269816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating NADP(+)-dependent
                     phosphogluconate dehydrogenase"
                     /protein_id="HFC6883884.1"
                     /translation="MKGDIGVIGLAVMGQNLILNMNDCGFKVVAYNRTIGKVDEFLNG
                     AAKGTDIVGAYSLQDLVDKLAKPRKIMMMVRAGSVVDDFIEQLLPLLEEGDIIIDGGN
                     ANYPDTTRRTHYLAEKGILFVGAGVSGGEEGARHGPSIMPGGDERAWEAVKPIFQAIA
                     AKTPQGEPCCDWVGRDGAGHFVKMVHNGIEYGDMQLICEAYQFMKDGLGLSYDEMHRV
                     FAEWNKTELDSYLIEITAAILGYKDEGGEPLVEKILDTAGQKGTGKWTGINALDLGIP
                     LTLISEAVFARCVSSFKEQRVQTGKLFARTVTPVEGGKQEWVEALRQALLASKIISYA
                     QGFMLIREAGESYGWDLDYGNTALLWREGCIIRSAFLSNIRDAYENNPDLVFLGADPY
                     FKNILENCLPAWRKVVAKAVECGIPMPCMASAITFLDGYTTERLPANLLQAQRDYFGA
                     HTYERTDKPRGEFFHTNWTGKGGDTASTTYDI"
     gene            complement(32990..33253)
                     /locus_tag="ACFOAE_000317"
     CDS             complement(32990..33253)
                     /locus_tag="ACFOAE_000317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883885.1"
                     /translation="MPSAQQANCPQKLFFMKNNPQVCTKGNPPYRHPFKTEIPMIFKI
                     KKSYPQKISPINIIIVFLFKFYILFISLQGNGTGKRKDIFSKN"
BASE COUNT         8599 a         9434 c         7749 g         8247 t
ORIGIN      
        1 tttttgttaa tccactataa aaacacaacc taaataaaaa tgccgtctga accatatttc
       61 aggtttcaga cggtatttgc gtgtcggatg cacaccggac aggcggtaag ccgggttctg
      121 tctcggacag tcattcctct aggcataccg ttgccagtat gctcaagcaa cctacccgaa
      181 cgctcggcgg gcagcgtcat tgcgttctgt ttggtcttgc tccgaatggg gtttggcctg
      241 ccgcatattg ttaccaaatg cgcggtgcgc ccttaccgca ccttttcacc cttgcctgtg
      301 ctgccaaagc agccatcggc ggttttgctt tctgttccac tttccgtcgc gttaccgcgc
      361 ccggccgtta accggcattc taccctgcgg agcccggact ttcctccccg tatgccttac
      421 gcgatacgcg gcgactgtct gcccatcccg tgtgcggcgc ggattataac acgaaacgca
      481 aaaataccgt ctgaaacggt acaggtttca gacggcatac ggttcaaact acacgccctg
      541 tttcaggctg gcttcgataa agccgtccaa atcgccatcc aatacggctt tggtgttgcc
      601 gacttcgtag cctgtacgca agtctttgat acgtgaggaa tccaaaacat acgaacggat
      661 ttggctgccc caacctacat cggatttacc ttcttccaac gcctgtttct cttcgttgcg
      721 tttgcgcatt tccaattcat acagtttgga tttcaacatt tccatcgcgg ccgctttgtt
      781 ggcgtgttgc gaacggtcgt tttgacattg caccacaatc cccgtcggct cgtgggtaat
      841 acgcacggcg gagtcggttt tattgatgtg ctgaccgccc gcgcccgatg cgcgataggt
      901 gtcgatacgc aaatcggcgg ggttgatttc gatttcaatg gaatcatcga tttcagggta
      961 aacgaacacg gaggcaaacg aagtatggcg tttgttgttc gagtcaaacg gtgaatagcg
     1021 caccaagcgg tgaacgccgg tttcggtacg cagcaaacca taggcatatt cgccttccac
     1081 tcggatagtc gcgcggttga tgcccgcgat ttcgccgtcg tcttcttcga ggatttcgat
     1141 tttgaagcct ttgcgctcgg cgtagcggct gtacatacgg aacagcatac ccgcccagtc
     1201 ttccgcttcc gtaccgcctg cgcctgcggt aatgtcgata aagcagttgt tcggatcggc
     1261 gggctggttg aacatccgtt tgaactccaa atccgccatc tgtttttcca gccccgccac
     1321 atcttcctgc acggcggcaa aaccttcttc gtcgttttct tcgacggtca tttcaatcag
     1381 catgcggttg tcttcgatgc ccgaagcgat gttgtcgagc gtcaacacga tgccttcgag
     1441 gattttgcgc tctttgccga tttcttgggc gcgtttcggg tcgttccaaa gttcggggtc
     1501 ttcggaaaga ccgacaactt cttccaatcg gtctttctta ccctgataat ccatataaac
     1561 tcggatgtct tcgctgcgct tttccaaatc attcagggta ttgttgagct ggttgattac
     1621 ttcggcttcc atgattcttt tgttctttca aaattttagg ggcgtattgt acgggattcg
     1681 ggtatttttt tctatggata aagccttctg gaaacacgtt cagacggcat agcgtcaata
     1741 acggtatgcc gccagtttgc gtttgatttc aggcaatgcg gcacgcgctg cctcctcgcc
     1801 caaccgaatg gcgcgttttt tctgatcgaa accgccgact gcacccaaat ccaaaacctg
     1861 cggtttgata accacatccg cctgccccaa ctcattttgc aacgcagaaa cgctcattac
     1921 gttcagcgtc tgatcgagat aagagaagaa accttggctg atgtttttgc ccggacgggc
     1981 ggaaatatcg acggcaatca cgaaattcgc cccctgccgc cgggcggcac tgacgggcac
     2041 gggctgcgac agaccgccgt caacatatgt atgcctgccg atgataacgg gttggaacac
     2101 attgggaatg gcggcggaag cgcgcacagc ctgcccggca ttcccttgat tgaaagcgac
     2161 ggccttgccg gtttcaaaat cagtagcaac agcggcaaat ttgatgggaa actgctgaat
     2221 ccgcctgccg ccgacttttc ggttgatgta attttgcagc ttttcgcctt tgataaaacc
     2281 actggtggac aaggttaaat cgactaaatc ggttttgcct aaaatttcgg cttccaattc
     2341 gaggcggtcg ggcgacatac ccgatgcaaa aaggctgccg acaatcgaac ctgccgatgt
     2401 accggtaacc accttcacag gaataccgtt ttctttcaaa accttaataa tacctacatg
     2461 ggcaaatcct ttagatgcgc cgccaccgag tgccaaaccg accactgcgg cgggtttggc
     2521 ggtttgcacc ggcttgcggg cggcattatt tcccgccgtg ccgcaggcgg caagcaacgc
     2581 ggcggcggcg attgccaaaa gcggtctgat ttttgaaaac gttaccatat tttccattcc
     2641 tttatatatc gcaccccgtc aaaaagaggg attgcttttc ttaacaaccc cctttgacag
     2701 ccaagcaaat gggggctttg ttaggtcatc atcaaaatta atatttcttt ttttccttta
     2761 cggaaattat atttgaaggc atactatcca aggtgggaat tatctcacaa caccgccgtt
     2821 atccaaatat cccgcctttt tcccttcctt tccatcaaaa tactttcttt ttatattcat
     2881 taacttgtta aatcattggc tgccgggtgt cagtttttcc gacaaaatcc gtctaatggg
     2941 gtatcaacag aaccaaaaca ggaacactta tgaaaatcgg aacaacttgg cagacggcat
     3001 ccgctatgct ggttttgcgt ctgtttgccg catatgaatt tttggaatcg ggtttgcaaa
     3061 aatggaacgg ggagaattgg ttttctgaaa tcaacgatca attcccattc ccgttcaact
     3121 tgctgccgga cgcgttaaac tggaatctcg ctatgtatgc ggagctttta ctgcccgtac
     3181 tgttgctttt gggtttggca acgcgtctgt cggcattagg gctgatggtc gttaccgccg
     3241 tcgcttgggc tgcggttcac gccggttcgg gttacaatgt ctgcgacaac ggttataaaa
     3301 tggctttaat ttatatcgtg gtattaatcc cgctgctttt ccagggtgcg ggcggatggt
     3361 cgctggatac gctgctgaaa aaacggtttt gcccccaatg ccgtctgaag caagattgat
     3421 tcagtcgtgg aatctgactt taaacattcc aaccttatct cgttaacttg atattctgaa
     3481 aaggaaatag aaatgaacaa aaacattgct gccgcactcg ccggtgcttt atccctgtct
     3541 ttggccgccg gtgcagttgc tgccaacaaa ccggcaagca acgcaacagg cgttcataaa
     3601 tccgcccatg gctcttgcgg cgcgtccaaa tctgccgaag gttcgtgcgg cgcggctggt
     3661 tctaaagcag gcgaaggcaa atgcggcgag ggcaaatgcg gtgcgaccgt aaaaaaaacc
     3721 cacaaacaca ccaaagcatc taaagccaag gccaaatctg ccgaaggcaa atgcggcgaa
     3781 ggcaaatgcg gttctaaata atcccacccc ttcaaaccaa gccgcgtttt tcagtaaaat
     3841 gcggcttttt taacggcaaa caaagatttt ttaacaagca catcattctt ttgtgccatc
     3901 cgaaccgggt aaaaatatga ttcaacacgc aggcttgggc taccgccgcg acttggcgga
     3961 agactttctc tcgctttccg aaaacagccc gatatgcttt atcgaagccg caccggaaaa
     4021 ctggctgaaa atgggcggct gggcacgcaa acagtttgac cgtgtggcgg aacggctgcc
     4081 gctggcgttg cacggattgt ctatgtcgct gggcgggcaa gcaccgctgg atactgattt
     4141 gatagacggc atcaaagaaa tgatgcgccg ttacgattgc acgtttttct ccgaccattt
     4201 gagctactgc cacgacggcg gtcatcttta cgatttgttg ccgctgccct ttaccgagga
     4261 aatggtgcat catacggcgc ggcgtatccg cgaagtgcaa gaccgtttgg gctgccgcat
     4321 cgccgtggaa aacacgtcct actatctgca ttccccgctt gccgagatga acgaggtcga
     4381 gttcctcaac gccgtcgcac gtgaggccga ttgcggcatt catctggatg tgaacaatat
     4441 ctacgtcaac gccgtcaatc acggtctgct gtcgccggag gcttttttgg aaaatgtgga
     4501 tgcagagcgc gtgtgctata tccatattgc cggacatgac gtggaaacgc cggaattgtt
     4561 gattgataca catggcgcgg cagttttgcc gactgtttgg gacttgctcg aacttgccta
     4621 tgccaagctg ccgacgattc cgcccaccct gttggaacgc gattttaatt tcccgccttt
     4681 tgccgaactc gaagccgaag tcgccaaaat cgccgattat caaacgcgtg ccggaaagga
     4741 atgccgccgt gcagcctgaa acctccgccc aataccagca ccgtttcgcc caagccatac
     4801 gcgggggcga agccgcagac ggtctgccgc aagaccgact gaacgtctat atccgcctga
     4861 tacgcaacaa tatccacagc tttatcgacc gctgctatac cgaaacgcgg caatactttg
     4921 acagcgaaga atggagccgt ctgaaagaag gtttcgtccg cgacgcgcac gcccaaacgc
     4981 cctattttca agaaatcccc ggcgagttcc tacaatattg ccaaagcctg ccgctttcag
     5041 acggcatttt ggcactgatg gattttgaat atacccaatt gctggcagaa gttgctcaaa
     5101 ttccggatat tcccgacatt cattattcaa atgacagcaa atacacacct tcccctgcgg
     5161 cctttatccg gcaatatcga tatgatgtta ccgatgattt gcatgaagcg gaaacagcct
     5221 tgttaatatg gcgaaacgcc gaagatgatg tgatgtacca aacattggac agcttcgata
     5281 tgatgctgct agaaataatg ggttcctccg cgctttcgtt tgacaccctc gcccaaaccc
     5341 ttgtcgaatt tatgcctgag gacgataatt ggaaaaatat tttgcttggg aaatggtcag
     5401 gctggactga acaaaggatt atcatcccct ccttgtccgc tatatccgaa aatatggaag
     5461 gcaattcccc gggccaaaac catctatccg cataaaatta ccttgttccc gatactatgc
     5521 cgctacccga cctgaccgat gccgaattaa tagagtcgcg taaactgctt ctgcattttg
     5581 cgcggcttca attgcccgac caccctgatt tggctgaaga tttagtgcag gaaacattgc
     5641 tgtccgcata cagcgcaggc gacaattttc aaggcagggc acttgtcaac agctggcttt
     5701 ttgccatatt gaaaaacaaa attattgacg cattacgtca aatcggaagg cagaggaaag
     5761 tctttaccac actggatgac gagctgctgg atgaagcatt tgaaagccat ttttcccaaa
     5821 acgggcattg gacgccggaa gggcagccgc aacattggaa cactccggaa aaatcattaa
     5881 acaacaacga attccaaaaa attctgcaaa gctgcctata caacttgcct gaaaacaccg
     5941 cacgggtatt taccctgaag gaaatactcg gtttttcatc cgacgaaata caacaaatgt
     6001 gcggtatcag cacgtccaac taccacacca ttatgcaccg cgcccgagaa tcattgcgcc
     6061 aatgcctgca aatcaaatgg ttcaaccaag aaaacccgaa gtaaacgtta tgaaaaaatg
     6121 ccgcgatatc accctgcttc tttccaaaca tcaggaccgg gaaaccaccc cgggcgagaa
     6181 gatttccata tacacacacc tgctgttctg tccgtattgc cgtgaatata aaagacaact
     6241 tcaaaccatc aaaagatcac tggcaaaaac aaccagaact tcaaaataaa tgccgtctga
     6301 aaaggcttca gacggcataa gctgacggaa acaaatcaaa ccgatttact gttatcggca
     6361 gttcatccat aatacacgct tcaaaagcag catattcctc catacggaat atataaatac
     6421 gcaaaacacg aaggctgcat caatttgctt tatttgcctt atttcacaga cggcgctacc
     6481 cctcccgccc aacccgttct ttctgaatga gcagatttca atgattaagg aaaccctaat
     6541 gcgcccaatc ttcctatctt tcgttttact ccctattttg ataaccgcct gcagcacacc
     6601 ggacaagtct gcccgatggg aaaatatcgg cacaatctca aacggcaata ttcatacata
     6661 tatcaataaa gacagcgtga gaaaaaacgg aaatctgatg attttccaag ataaaaaagt
     6721 tgttaccaat ctaaaacaag aacgttttgc caacaccccc gcatacaaga ctgccattgc
     6781 cgagtgggaa atccactgca acaacaaaac ataccgctta agttcgctac agttgtttga
     6841 tacaaaaaac acggaaattt ccacacaaaa ctacacagcc tcttccctcc gcccgatgag
     6901 catcctgtcc gggacattaa ccgaaaaaca atatgaaacc gtatgcggaa aaaaactctg
     6961 attgcaactt atacacaaac ctacccacaa accttgtcat aaaaatgccg tctgaaatac
     7021 tgaaatatca gcatttcaga cggcattttg ccattccctg aaaattatcc acaaagttat
     7081 ccacattatt tttaaaaccg gcttccatcc gaaatatagt ggattaacaa aaatcaggac
     7141 aaggcgacga agccgcagac agtacaaata gtacggcaag gcgaggcaac gccgtactgg
     7201 tttaaattta atccactata caaatacaga aactcaagaa aataaccttg tgtattgacc
     7261 atctcaagca attcagaaaa atcaagaaat tttctgaccg taaacaaacg tttccctaaa
     7321 aaaacgatgt cttcaaaaat atcgaacaaa taatcatctt cggcgttttc atttttatgg
     7381 gttaaaacaa cacgggaaaa atctgttttc agatgcttgc ccgcttgatt gttcggatta
     7441 ttgtccggaa cgacaaaacc gtcctcaaaa ttaaagcaga cgttgcgtcc ttctaccttt
     7501 atctctgtgc aataacaatc atgtagagaa atgctatccg aaaaattttt tctttgtgta
     7561 tgcaaaaaaa gttttcattc aagtacccat atctaacgca aacgtttacc tgttttcccg
     7621 tcaataatct gactcggcga tttctgcctg ccgattctcc caccaacaat ccacacatcg
     7681 cgtccgaatt gccttctgac ttccctctcc gtccgacacg cgcgtttgcc tgcgcggttg
     7741 cacgaagtcg agaccaaagg cgtttgcaaa gcctgacaca agcggcgcgc acctacatgg
     7801 gcgggaaccc tgaccgccaa cttgctgcgc tgtttcccgc gtaactcggg taagacacag
     7861 gatttggcgg ataataggaa cgttttaggg gcgggccatt cttttctaag catatcctga
     7921 agattttcag acggcatttg aagtaaaggc tgcaattgct caaattgatt cccgatgaca
     7981 atcataccct tgtgttgcgg tctttttttc aaatgcgcca acttaccgag tgctttggct
     8041 aatgtcggaa gacaccccaa gccataacaa gattcggtcg gataagcgac caaaccgcct
     8101 tttttcaaat aaacgcttaa cttacgttgc gctgatgctg cgataattct cggaaataac
     8161 ataatataaa ataccgtctg aagcacatca gtcatacttg gcttcagacg gcatcatcct
     8221 ctttctaatt aacggttaat cgctttatcg gcaatgtctt tacggtattg catcccgtcg
     8281 aaactgattt tttccaacgc gccatatgcc ttagctttcg cttgcgccac attatcgccc
     8341 aatcccacaa cacacaatac gcgtccgccg ttggtcaata cgtcaccttt ctcgtttgcc
     8401 gttgtacctg catggaaaac tttgcctact tggttggcag catccagacc ggaaataaca
     8461 tcgccttttt tgggcgtttc ggggtaattt tgcgccgcca gtaccacgcc cacggcagtt
     8521 tgcgggctcc attccgcggt tacgctatcg agtttgccgt ctattgccgc ttcaaccaaa
     8581 tccgataagt cgctgttcag tcggctcata atcggctggg tttcaggatc gccgaaacgg
     8641 cagttaaact caatcgtatg gggtgcaccg ctttgatcaa tcatcaaacc tgcgtacagg
     8701 aaaccggtga actcatgccc ctccgctttc atccctgcta cggtcggcaa aataatttca
     8761 ttcatcgcgc gttcgtacac aacaggcgtt accacaggcg cagggctgta cgcacccata
     8821 ccgcccgtat tcagaccttt gtcgccgtct aaaagacgct tgtggtcttg gctggttgcc
     8881 ataggcagta cattattgcc atcaaccatg acgataaaac tcgcttcttc gccttgcagg
     8941 aaatcttcaa tcacaatacg cgcgccggca ttgcccattt tgttgtccag cagcatatca
     9001 tcaatcgcag catgcgcttc atccaaagtc atcgccacaa tcacgccttt acctgccgcc
     9061 aaaccatcgg ctttgataac gataggcgca cctttctgat tgacgtaatc atgtgcggca
     9121 tcggcgtttt caaaggtttg atattgcgcg gtcggaatat tgtatttcgc cataaatgct
     9181 ttggcgaaat ctttggaact ttccaactgc gccgcatatt gtgtcggacc gaatattttt
     9241 agtcctgcag cacggaaatc atccacaaca cctgccgcca aaggcgcttc agggccgacg
     9301 acggtaaaaa caatattttc tttacgacag aattcaatca aatcctgatg cgcagtcaag
     9361 tcgatgtttt gcagcttggg ttcaatcgct gtaccggcat taccagacgc aacaaatact
     9421 gtttccactt taggcgactg cgccaatttc caagccagcg cgtgttcgcg accgccatta
     9481 ccgataacca gcagtttcat gccatctcct tgacaaatat gtacttttaa cgaaaactcg
     9541 atacaaaggg acttttatcc catctgaaga aattttagta gaatcaaaca aaagaccgct
     9601 tcattccact ctgcaaccta ttcaacttat tcataaatta aaaaaggaca agcaaccatg
     9661 caaaaacgta ttgatgaaat ccaaagcaaa taccgcgaat ggtgtcattt actaccgcaa
     9721 ttggaagaag acatccgccg ttggaaacat gccgtcgctt tgattcgcga tatggacaat
     9781 ttttataccc acgaatatca ggcttgtcat cgggctattg aagatggagc ggaggtggat
     9841 ttgcgcacag aaggcgaata cagcattatg agtgaagatg cactatggaa cgcgctgggc
     9901 gaattccatc aactggcttg gttatatttg cgctccagcg tcgatgcctt agacaaatat
     9961 acacaagaag attagtcagc gaagaggtcg tctgaaatac catcacaaag catttcagac
    10021 gacctttcat tcaaaaggct tttccgtatt tacttcaatc tgccgtgtac tcttccaagc
    10081 cgcaacacag gcctcataat ttaccaacga caaactgacc gtcaatcggc aatccaactg
    10141 caaatcccgc tccaatacat ccgcctgata ttgtttagca atgcgtatcg cttcattcaa
    10201 aaacggatat tcacatttca gccaaacagt tttttcaata ttcttttcaa ctacttctgc
    10261 aactgccaac gcttgagccg tcgcctcttt gtacgcatgt atcagacctg gaacacctaa
    10321 caaagtacca ccgaaatagc ggacgaccac aaccaaaacg tcggtaatac ccaccgaatc
    10381 aatctgtccc aaaattggtc gtccagcact tcctgatggc tctccatcat cgttggcacg
    10441 aaattgcatg ccatccacac ccaaacgata ggcatagcac cagtgtcgtg ctttatgatg
    10501 ctcttccttt aacggatcga ggtatttttt cacatcagcc aatgtccgaa tcggataggc
    10561 aaatgcaata aaacggctgc ctttatcttt aaactcagcc tgcgtcgagg aagtaatggt
    10621 tttataagtc gtaatcatgc tgaaatgttt tcagacgacc tcattaataa caaggtcgtc
    10681 tgaacgtttc acgtgaaaca ttaatttttc aatacttctg ttaattgtgg aacgatttca
    10741 aataaatcgc caaccaatcc gtaatcggct acattgaaaa tcggcgcatc agcatcttta
    10801 ttgattgcaa caatcacctt actgtcttgc ataccggcaa cgtgttgaat cgcacctgaa
    10861 ataccgattg caaaatagag ttgcggcgca actactttac cggtttgtcc gacttgagca
    10921 tcgtttggcg catattcggc atcaaccgcc gcacgggatg caccgattgc cgcacctaaa
    10981 acatccgcca acggtgtcag cacttcattg aatttttccg cactacccaa cgcacgacca
    11041 ccggaaacaa tcacttttgc ctgagtcagt tcaggacgat cggaatggga aagctgacgg
    11101 ttaacaaaac gactcaggtt ttgggcaggg gttgcttcaa cattaattac ctcagcatta
    11161 ccaccttgcg ccgccactgc gtcaaaaacc gtcgcacgga aggtcagcac caatttttct
    11221 gaatcagctt gcacggtttc aaatgcatta cccgcataaa tggggcgcac aaaagtcgtg
    11281 ttatccacaa tttcggtcaa atcagaaatt tgcggtacgt ctaataaggc tgctacgcga
    11341 ggcaaaaggt ttttaccgaa tgtagttgcc gttgctgcaa catagcagta atccgctgcc
    11401 aatttaacaa ccagcggagc caactcttca gccaaacctt cggcataatg ggcagcatct
    11461 gcaaccaaaa ctttttccac acccgccact tgttttgcga actctaccac agcagatgca
    11521 ccgcttccgg caaccaataa atcgatttta cccagcttag cggcagcggt aacagcatgc
    11581 aaagtggtag gattcaactg tttgttgtcg tgttcgacaa taatcaatac actcatttca
    11641 gcctcctcaa atcactttgg cttcgttttt caatttttca accaattcgg caacgcttgc
    11701 tacttttacg cctacctgac gcgccttagg ttcggcaaat ttcaccgttt tcaaacgagg
    11761 tgaaatgtcg gcaaccaaat cgtcaggagt cagtttttcc aaaggttttt tctttgccgc
    11821 cataatattg gggagtttga caaagcgcgg ctcgttcaaa cgcaaatccg cgctgataac
    11881 agcaggcagt ttcaatgcga tggtttcttc gccgccatca atttcgcgca caatctgtac
    11941 ttcaccacct tcaatgtgta cttttgaagc aaacgtacct tgcgccgcat tcagcaaagc
    12001 tgccagcatt tgcgccactt gattggcatc atcatcaatc gcttgtttgc ccaaaaagaa
    12061 aatttgcgga ttttctttgt ccgcaacggc tttcagcaac ttagcaacgg ccagagactc
    12121 cagtttagta tcggtttcaa catgaatggc acggtcggca cccatcgcca aagctgtacg
    12181 caacgtttct tcgcatttct tttcgcccaa agaaaccgct acgatctcgc ttacttttcc
    12241 ggcttctttc aaacggacgg cttcttccac agcgatttcg tcaaacggat tcatcgacat
    12301 tttgacattg ccgatatcca catccgaacc atcggctttt acacgaactt tgacgttgta
    12361 gtccactacg cgctttactg cgaccagtgc tttcattgaa ccctcctaaa aagaacgctg
    12421 ctttcaccat ccagcgaaac caaaccttct tccctataaa accaaatccg ttttccttaa
    12481 aaacgaattc attcaaaaat ctttcggata atgcttgccg attataccat ttttaaagca
    12541 tttactcaga ctagcggata tacattcctg tatctaataa attggaaaat atcatgccgc
    12601 catatcagtt ttagacgacc ctttagcctt tatctgctgc aacacaatcc atcagcgctt
    12661 gataaaccaa atctgcggtc ggaatctgcc cgatattgcc caaatttttt gcaattggcg
    12721 aaacctgaac gcctgtttta atcggatcgg tatcggtata aatgccgacc acaggttttt
    12781 ccaaggcgtt tgccaaatgc agcaaaccgg tatccacgcc aacaattccg accgcgtgtt
    12841 tcagcagata cgctgcctgc aataaattca ttttatcgca cacaatagca aacggcagtc
    12901 cgtctgcaat ttgtttggca cgcgtttttt catcttcatt tccccaaggc aggtaaatat
    12961 tgcattgctg ttcttcattc aacttttgca gcaacgaccg ccagttttcc acaggccata
    13021 acttactgtc ccgactggtc gcatgcaaag ccgcataata cggctgcgct aaatttttca
    13081 gacggcctgc ctcaggaaca gtcaagccaa atacctgcgt ttcaggcatc gcatacccaa
    13141 atacttgggc gaacagctca cgattgcgcc aaacagcatt tttccctttc ggtacagcgt
    13201 atgttttcgc atacgccagc gcagccagtc cctcgcgcgc gctattttta tccaaaccat
    13261 aaatagggga tttcgccatt ttagcgaaac acgcgctttt aatcagacct tgactgtcca
    13321 atacaaaatt aaatgcttcc tgccgcaaag tctgtttcag atgacccatt tcccgccaag
    13381 tttcagcctg aaagagatgt ttgcgccatt gccgccattt catcacatgg atttttttta
    13441 caaacggatg caggcgcgca atatctgcaa atccagcctc acatagccaa tgcagttcta
    13501 catcaggaca ttgtcgcgcc aaatcttcga ttgcgggcaa agtgtgaatt aaatcgccca
    13561 tactagacaa gcggacaagc aaaattttca tatttaagaa gtatgtttca cgtgaaacga
    13621 ttttaactta ttgattatta atatattttt taatttcttc ggcgtttttt aagatgacag
    13681 caccggcaga acgcatttcc tgccatgccg tttcaatggt atccggcgca ataccccgac
    13741 aagccgcttc attgacgata acctgccaat tgctaccttt gagcaactgc aaaaccgttg
    13801 ttttaacaca ataatccgta gccaaaccgc cgacaatgac catatccgta ttttgacaac
    13861 gcagccactc aatcaatcca gtgctcagtt tttcctcaat atcgtgaaaa cacgcgccgt
    13921 aaggatgcaa ttcaggatca acacctttcc aaacgcaata atcgtattct ttggcagaag
    13981 gcagtccgtc caataattca tagccgcgcg taccgaccat cgcatgagcc acccaagtca
    14041 aatccgcatc aggcaaacct gtcggcttca acatatcaac agggttatcc acaagccatt
    14101 tcgctaccat atgatgcgca tctttcgtca tcacgcgcaa atccgccaaa gcggcttggg
    14161 cattcaattc ttcgacaatc aaatgcccct cgtttacagg cagctcttta ggacacaaag
    14221 gcgtaaaagt tttttgtgca tcaacatcaa tggaaacaat catctcatca tttcaacgca
    14281 attaaaatgc cctgtattat aacaaattac tgcccaaaag cggtaaaaca ggctgtgata
    14341 agataaggtt tttccgaaaa acttatccac aatcctcatg acttacacca tcgtccctat
    14401 cgccaccgcc cgatcgccct acaaacagaa attcggcatc gcccgccagc ccggtttagt
    14461 ctccgccgca gaagtatgca tcgagctgaa tcccgaattt accgcagaca gcgtgcgcgg
    14521 gctggaagat ttcgattatg tgtggataag ttttattttt cacggcgtat tggatgaagg
    14581 ctgggcacaa atggtgcgcc cgccacggct cggcggcaaa caaaaaatgg gcgtattcgc
    14641 cacgcgcagc ccccaccgcc ccaaccatct cggactatca ctcttaaaac tcaaccgcat
    14701 cgaaaccggc aaacccgtcc gcctttattg cagcggcgca gacctgctcg acggcacgcc
    14761 gattgtggac atcaagcctt atatcccctt tgtcgaatcc aaacccgatg ccgcatctgg
    14821 tttcgtcagc ggcaaacccg tagagttgga agtcgtttgg caggaaaaca tcggcgcgga
    14881 aaatttatct gcaaacacca aaaaccttat cagccaaagc attgcccaag atccgcgccc
    14941 cgcctatcag aatattcccg aacggattta tgtgatgaat attgcggatt acgaaatcag
    15001 atttcaaatc gaggaaaacc gtgcaaccgt tattgatctt tccccaaccc cgctttaaat
    15061 cgggcaaaaa tccggttttg ccgcatagca gttgaacaaa cggctgttgt ttgttcgcca
    15121 taagccgcaa tatcaagtta tagcggatta aatttaaatc aggacaaggc aacgaagccg
    15181 cagacagtac aaatagtacg gcaaggcgag gtaacgccgt actggtttaa atttaatcca
    15241 ctatacagat aaacaatgcc gtctgaacgc aatgtgttca gacggcattt acttatccac
    15301 aggtttgttc aagccttaga ttttgcctgc gaagtattcc aaagtgcgga cgagttggca
    15361 ggtgtaggac atttcgttgt cgtaccaggc aacggttttc accagttgtt tgccgcccac
    15421 ggtcatcacg cgggtttggg ttgcgtcaaa gagcgagccg tattcgatgc cgacaacgtc
    15481 ggaagaaacg atttgatctt cgttgtagcc gtaagattcg ctggcggctg ctttcatcgc
    15541 ggcgttgatt tcttctttgg ttacagggcg ttcgaggacg gaaaccaatt cggtcagcga
    15601 gccggtggca acagggacgc gttgggcgga gccgtcgagt ttgccgttca attcggggat
    15661 aaccagaccg atggccttgg cggcaccggt gctgttgggc acgatgttga gcgcggcggc
    15721 tcgggcgcgg cgcaaatcgc ctttgcggtg cggcgcgtca agggtgtttt ggtcgccggt
    15781 gtaggcgtgg atggtggtca tcagaccttc gactacgccg aactcttttt gcaggactgc
    15841 cgccatcggg gcaaggcagt tggtggtgca ggaagcggcg gagataacgg tttcgctgcc
    15901 gtccaaaatg tcttggttta cgccatatac gacggttttc acatcattgc cgccgggtgc
    15961 ggaaatcacg actttgcgcg cgccggccct gatgtgtgct tcggctttgg ttttattggt
    16021 aaagaagccg gtacattcga ggacgacatc cacacccaac tcgccccaag gcaattcttc
    16081 gggattcgga ttggcgaaaa ctttgatttc tttgccgttt accacgatgg catcgtcttt
    16141 taattcggca gtaccttgga aacggccttg cgtgctgtcg tatttgaaaa ggtgcagcag
    16201 catttcggca ggggtcaggt cgttgacagc gacgacttcg atgccgtggg ctttttcaat
    16261 ttgacgcaat gtgaggcggc cgatgcggcc gaaaccgtta atcgctactt taatgctcat
    16321 gtatatactc caagctgtga aacgaaattt caatatctgt attgtattct gaaataaagt
    16381 tacattccac tattacatct aactacttga tgcttatttg atatagatga attttactgt
    16441 ttgcacagat ttccaaaact tttaccatca atatttgaat ttaaaatttt aatgatgatt
    16501 ttgatgattg cggatctgct tgtgtataag tagcaaatat ccaatatttt cattaccttt
    16561 ttgtcaaata agtttgagtt taagacttgc tgtataagac agataagcgt ggatgttttt
    16621 tgacttaata atatttctgt ggataacttt gctgttttcc tagttgtctc cacaacctta
    16681 ttgacaggct tacggtcagt ctcattccgt cgaagacaaa accttttgct acaataccgt
    16741 tttcctaatg ataaggcagc cccatgtcca aatccgccgt ttccccaatg atgcagcaat
    16801 acctcggcat caaagcgcaa cataccgaca aactggtgtt ttaccgtatg ggcgattttt
    16861 acgagatgtt tttcgacgat gcggtagaag cggcaaaact tttggatatt accctgacca
    16921 cgcgcggaca ggtggatggc gagccggtca aaatggcagg cgtgccgttt cacgccgccg
    16981 aacaatatct ggcgcgcctg gtcaagttgg gcaaaagcgt ggcgatttgc gaacaggtcg
    17041 gcgaagtcgg cgcgggcaaa ggaccggtgg agcgcaaagt cgtgcgcatc gtaacgcccg
    17101 gcacgctgac cgattccgca ttgctggaag acaaggaaac caaccgcatc gttgccgtgt
    17161 cccccgacaa aaaatacatc ggtttggcgt gggcatcgct gcaaagcggc gaattcaaaa
    17221 ccaagctgac aactgtggat aaattggacg acgaactggc gcgcctgcag gcggcggaaa
    17281 ttctgttgcc ggacagtaaa aacgcaccgc aacttcagac ggcatcgggt gttacgcgcc
    17341 tgaacgcgtg gcagtttgcc gccgacgcgg gggaaaaact gctgacggaa tatttcggct
    17401 gccaggattt gcgcggcttc ggtttggacg gcaaagaaca cgccgttgcg attggcgcgg
    17461 caggtgcact gttgaactat atccgtctga cgcaaaacct gatgccgcaa catttggacg
    17521 gcctgtcgct cgaaaccgac agccaatata tcggtatgga tgccgccacg cgccgcaatc
    17581 tcgaaatcac gcaaaccctc tccggcaaaa aatcgccgac cctgatgtcc acgctcgacc
    17641 tttgcgctac ccatatgggc agccgcctct tggctctctg gctgcaccac cctttacgca
    17701 accgcgccca catccgagcg cgccaagaag ccgttgccgc gctggaaagc caatacaaac
    17761 ccctccagtg ccgtctgaaa agcattgccg acatcgaacg catcgccgcc cgtattgccg
    17821 tgggtaacgc ccgcccgcgc gacctcgccg ccctgcgcga cagcctgttt gccctgtccg
    17881 aaatcgaatt gtccgccgag tgcagcagtc tcttaggaac cctcaaagcc gttttcccgg
    17941 aaaacctatc cacagccgaa cagctccgcc aagccatttt gcccgaacct tccgtctggc
    18001 tgaaagacgg caatgtcatc aaccacggtt ttcatcccga actggacgaa ttgcgccgca
    18061 ttcaaaacca tggcgacgaa tttttgctgg atttggaagc caaggaacgc gaacgtaccg
    18121 gtttgtccac acttaaagtc gagttcaacc gcgttcacgg cttttacatt gaattgtcca
    18181 aaacccaagc cgaacaagca catgccgact accaacgccg gcaaaccctc aaaaacgccg
    18241 aacgcttcat cacgccggag ttgaaagcct ttgaagacaa agtgctgact gctcaagagc
    18301 aagccctcgc cttagaaaaa caactctttg acggcgtatt gaaaaacctt cagacggcat
    18361 tgccgcagct tcaaaaagcc gccaaagccg ccgccgcgct ggacgtgttg tccacatttt
    18421 cagccttggc aaaagagcgg aacttcgtcc gccccgagtt tgccgactat ccggttatcc
    18481 acatcgaaaa cggtcgccat cccgttgtcg aacagcaggt acgccacttc accgccaacc
    18541 acaccgacct cgaccacaaa caccgcctca tgctgctcac cggccccaat atgggcggca
    18601 aatccaccta catgcgccaa gtcgcgctga ttgttttatt ggcacacacc ggctgttttg
    18661 tgcctgccga tgccgccaca atcggaccca tcgatcaaat cttcacccgc atcggcgcat
    18721 cggacgatct cgcctccaac cgctccacct tcatggtcga aatgagcgaa accgcctaca
    18781 tcctgcatca cgccaccgaa caaagccttg ttttaatgga cgaagtcgga cgtggtactt
    18841 ccactttcga cggcctcgcc ctcgcgcacg ccgttgccga acacctgctg caaaaaaaca
    18901 aatccttcag cctgtttgcc acccactatt tcgagctgac ctacctgccc gaaacccacg
    18961 ccgccgccgt caatatgcac ctttccgcgc tcgaacaggg acaggacatc gtgttcctgc
    19021 accaaatcca accggggccc gccggaaaaa gctacggcat cgccgtcgcc aaactcgccg
    19081 gcctgcctgt acgcgcattg aaatccgccc aaaagcattt gaacgaactg gaagaccaag
    19141 ccgccgcaaa ccgtccccaa ctggatattt tcagtaccat gccgtctgaa aaaggagatg
    19201 aaccgaatgt ggacagcttt gtggacaaag cagaggaaaa acattttgaa ggtatattgg
    19261 cagcagccct ggagaaactc gatcccgaca gactgactcc gcgcgaagca ttgtcagaac
    19321 tgtaccgtct gaaagatttg tgcaaatccg tatcttaatt tccgttgtcg gaacagcatc
    19381 aaaccatatg gaaaaatctg tggataaata ttatctgaca ggaagtttcc aaacataaaa
    19441 aatgccgtcc gaacagctca gacggcattt gtccattcgg cttaaacctt atccacatcc
    19501 aaacgcataa ccgtaaccca ttcaccgtta tggaaatgtc gcccgacaac cgcccagccg
    19561 aatgattcat aaaatatttg cacatcaggc gtataaagat acaagaactt tatccccagc
    19621 gaacgcgctg cgcctatgca gtgggcgacc agcctcctgc caatgccttt tccgcgatat
    19681 tcaggtaaaa caaagacatc ccccaaccaa tattcatact gtggaaaact ttccatatca
    19741 tgccgcttga ccgtagccga acccaacagg gttccggaat catccacagc cgcaaatgcc
    19801 agcggcagtt cgtcatcctt caaacatctg ccgtaatagg cacgaatctt atccacagaa
    19861 gaccacggtt caaatccgtg ccactcctca aacaacgcct gaaccaacct gccgatatgc
    19921 ccggctttca gccgtgtaat gaaaacagta ttgtccacaa agagggaatt catcggtcaa
    19981 ttccccgacg ccttcgttcc ccctgcgccg taaaccgcat tccaagcatg gtccaaacgc
    20041 actccgattt gcctcagctc ttcagcctgc cgggcttttt gcgccattgc tgcaggaatt
    20101 tccgcttcca aacgggcgat gtctgcctga gccgcctgca accgtctgcg cgcatcttcc
    20161 aaatccgact gcatcccgat aatttttccg tcaagcttgt tttgtttttg caataaggcg
    20221 cggtaaccgg attggatact gagcaaattg tcttcagcat cccctgccca tacactggta
    20281 gaaaaaacaa ccatcagaaa ataaaatatt tttttcatgt tcaacttccg tttgaatgcc
    20341 gtctgaagcc gcattccgac atcagacggc atcgcccacg cctgtggata acttaagcgc
    20401 ggatacgttt caacacttct tctttgccga ttaatgccaa cacggcatcg acgcttgggg
    20461 tcttcgccgt gccgcagaca gcgaggcgca aaggcatgcc gagtttgccc attttaatgc
    20521 cttcttcgtc acagaaaggt ttgaacaggt cgtggatggc ttcggtattc cagtcttcca
    20581 aaccctcgag gcgttcggca aagcgcagca tgcgtgccgc cgcttcgtca tcccagtgtt
    20641 tggcaacatc ggcttcggca gggacttgtt ttttgtagaa atacagacat tcgtctgcca
    20701 aggcgttcaa atcttgggcg cggtctttga cctgtgccaa cacgtcttcc aacgcaggtt
    20761 tttcagtttc atggatatcg cgcagagcga gacgcggttt gacgagttcg gcgagtttgc
    20821 cgttaggcgt gattttgatg tgttcgccgt tgatccaata gagttttttc aaatccatac
    20881 ggcttgggga cggggaaacg tctttcaaat caaaccattc gatgaattgt tccatcgtaa
    20941 agaactcgtc gtcgccgtgc gcccagccca aacgtgccag atagttgagc atggcttcgg
    21001 gcaggatgcc cattgcgccg aaatcggtaa tggcaacggt atcgccgctg cgtttggaga
    21061 tttttttgcc ttgttcgttg agaatcatcg gcaggtgccc gtattcaggc agggtagcgc
    21121 cgatggcttt taatatgttg atttgtttcg gggtgttgtt cacatggtcg tcaccacgga
    21181 taacgtgggt aacgcccatg tcgtagtcgt ctacgacaac gcagaagttg taggtcggtg
    21241 tgccgtcggc gcgtgcaata atcaggtcgt cgagcgcttc gttgggaatg gaaatttcgc
    21301 ctttgaccaa gtccgtccac tgggtgacgc cgtccaaagg tgttttgaaa cggacaacag
    21361 gttgcacgtc ggcagggatt tcgggcaggg ttttgcctgc ttccggacgc cagcggcggt
    21421 cgtaagtcgc cgtgccttct ttttcggctt tctcgcgcat cgcttccaat tcttctttgc
    21481 tgcaatagca gtagtaggca tcgccttttg ccaagagttc ggcaatgact tctttataac
    21541 ggtcgaaacg gcgggtttgg tacacgacgt tgtcggcgtt gtcgtaatcc agtccgaccc
    21601 atttcatgcc gtcgaggatg atgttgacgg attcggcggt ggaacgcgcc aagtcggtgt
    21661 cttcgatacg caataggaac tcgcctttgt gatggcgggc aaacgcccat gaaaacaagg
    21721 cggtgcgaac gccgccaatg tgcaggtagc cggtggggct gggggcgaaa cgggttttga
    21781 cggtcatgat ggctccagaa tctttaaaac ggcttatttt actgttttta ccgtgcttgg
    21841 gcattaaaaa tgccgtccga accctgcctg cggataagtt tcagacggta ttttccttgt
    21901 tttcaatgct tcggcacgcg gaacagtgta tcacgcgccg ccgaccgggt tcctttggga
    21961 ttgcgtccga aaaaaggttc aatgaaacag ccaattgaaa aaatcccacc cccatttttc
    22021 caaacggtag agggataacg catatccctc ttgcagcata aagatttttt tcttatttcc
    22081 cgcatcaaac cgcgtggtcg gggtggcaga catataaacg cggacaccca aatcctccgc
    22141 catttccgcc gcccgcgcca aatggtaggg atcgctgaca atcaccacgc tggcaatacc
    22201 gttggcacgc aaaaccggac ggatgttgtt caggttttca taagtgttgc gcgaagtgtt
    22261 ttcaaacagg atgttgcgcg ccggaacccc ctgtttgagc gcgtaccgcc gcccgacctc
    22321 ggcttcggtc atatagcctt ttttggttcg ccctcccgta aacacgattt tgcctaccct
    22381 gcggctctga taaagcgcga tggcgtggtt gatgcgttcc cgaaaaaccg gagaagggtg
    22441 tttgtcccac gcggcggcgc ccaacaccag cgcggcatcc gcccggacat acggcggcaa
    22501 aacctgaccg cccgtccgat aaaccgccca aacggatgag gcaaacacca tcaaaagcgg
    22561 aaaaacactc aaacagaaac cgcccaacag gtaatagcgc aagccgttgc ggctgcaaaa
    22621 cagccgtttt ttcacaatac cgcttcgata ttttccagcg gcctgcctac agccgcctta
    22681 ccgttcgcca aaacaatcgg acgctccaac agggcgggat gatcggcgat ggcacgcagc
    22741 agcgcgtcat tgtccaaatc ggggttgtcc aaacccaatt ccttgtacaa atcatctttc
    22801 acgcgcatca tcccgcgcgc cgatgccaaa cccaatttgt tgaaaatatc cttcaattcg
    22861 gacaagtcgg gcggcgtatc caaatatttg accacttcgg cagcaatgcc gcgttcttcc
    22921 aataaggaca aggcggcacg cgatttgctg caacgggggt tgtggaaaat tttgatttca
    22981 gacatgacat ttccttactt ctcgacaatc cccttattat cggcttacac agggttttac
    23041 tcaatatccc gcctacaacc gtaccaaacg gtttacaata cccgaatcga catacaaagg
    23101 acaaaacgat gaaatacttg aatcttgccg caatcaccct tgccgccaca tttgccgcac
    23161 ataccgcctc ggcagacgaa ctggccggat ggaaagacaa caccccacaa agcctgcaat
    23221 cactcaaagc ccccgtacgc atcgtcaacc tttgggcaac ctggtgcggc ccgtgccgaa
    23281 aagagatgcc tgccatgtcc aaatggtaca aagcgcagaa aaaaggcagc gtcgatatgg
    23341 tcggcatcgc gctcgacaca tccgacaata tcggcaactt cctcaaacaa actcctgttt
    23401 cctacccgat ttggcgttac actggggcga acagccgaaa ctttatgaaa acctacggaa
    23461 acactgtcgg cgtactgccc tttaccgtcg tcgaagcacc gaaatgcgga tacaggcaga
    23521 ccattaccgg ggaagtgaac gaaaaaagcc tgaccgaagc cgtcaaactc gcccattcaa
    23581 aatgccgtta aacgccggat gccgtctgaa tccgcttcag acggcatttt tcccgcccga
    23641 ccttcggtat ccgccaaact tatccactat ctaaaaacag gcggaatctt tataatcggc
    23701 actgtcttac ctattgttca gacggcatat ccctgcggac gcaaccgccc gaaacgatat
    23761 gccgcccttc cttacaggac ctcctatgat ccgtttcgaa caagtttcca aaacctatcc
    23821 cggcggtttt gaagccctga aaaacgtcag cttccaaatc aacaaaggcg aaatgatatt
    23881 tatcgcagga cactccggtt cgggcaaatc caccgtcctc aagctgattt cgggcatcac
    23941 caagccgagc aggggcaaaa tcctgtttaa cgggcaggac ctcggcacat tgtccgacaa
    24001 ccaaatcggc tttatgcgcc aacacatcgg catcgtgttc caagaccaca aaatcctcta
    24061 cgaccgcaac gtcctgcaaa acgtcatcct gccgcttcgg attatcggct atccgccgcg
    24121 caaagccgaa gaacgcgccc gcatcgccat cgaaaaagtc ggcctgaaag gacgagaatt
    24181 ggacgatccc gtaaccctct ccggcggtga acaacaacgc ctgtgcatcg cccgcgccgt
    24241 cgttcaccag cccggcctgc tgattgccga cgaaccctcc gccaacctcg accgcgccta
    24301 cgcgctcgat attatggaat tgttcaaaac cttccacgaa gcgggaacaa ccgtcatcgt
    24361 cgccgcacat gacgaaaccc tgatggcgga ctacggacac cgcatcctgc gcctctcgaa
    24421 aggacgactc gcatgagcat catccactac ctctcgctgc acgtcgaatc cgcgcgcacc
    24481 gcgctcaaac agcttctgcg ccaacctttc ggcacactgc ttaccctcat aatgctcgcc
    24541 gtcgccatga ccctgccgct gtttatgtat ttgggcatcc aaagcggaca aagcgtttta
    24601 ggcaaactca acgagtcgcc gcaaatcaca atctatatgg aaaccgccgc cgcacaaagc
    24661 gacagcgata ccgtgcgcag cctgctgacg cgcgacaaac gactcgacaa catccgcttt
    24721 atcagcaaag aagacggttt ggaagaatta cagtccaatc tcgaccaaaa tctgatttcc
    24781 atgcttgacg gcaaccccct gccggatgtc tttatcgtta cccccgacct ggcaaccacg
    24841 cccgcccaaa tgcaggcaat ctaccgggac attaccaaac tgcctatggt cgaatccgcc
    24901 aacatggata cggaatgggt acagacactg taccaaatca acgaattcat ccgtaaaatc
    24961 ttatggtttc tttccctgac gctggggatg gcgttcgtcc ttgtcgcgca caacaccatc
    25021 cgactgcaaa tcctcagccg aaaagaagaa atcgaaatca ccaaactctt gggcgcgccc
    25081 gcgtcgttta tccgccgccc cttcctttat caggccatgt ggcagagcat tctttccgcc
    25141 gccgtcagcc tggggctttg cggctggctg ctctcagccg tgcgcccatt ggtcgatgcc
    25201 atcttcaaac cctacggctt gaacatcggc tggcgtttct tttaccctga agaaatcgtg
    25261 ctggtgttcg gcttcgtcat cgcgttgggc gtattcggcg cgtggcttgc caccacacaa
    25321 cacctgctcg gcttcaaagc caaaaaataa aacaccgtca aaaatgccgt ccgaacccgt
    25381 tttcagacgg catttcaatt tgccagtata atggcgcatt tttccaacaa ggaatctacc
    25441 atgctgaccc cggaacaagt aaaagccatg attgcaggcg tggcaaaatg cgaacacatc
    25501 gaagtagaag gcgacggaca ccattttttc gccgtcatcg tttcatcaga atttgaaggt
    25561 aaggcacgcc tcgcgcgcca ccgcctgatt aaagacggac tcaaagccca actggaaagc
    25621 aacgaactgc acgcactttc catttcggtt gccgccactc cggcggaatg ggcagccaaa
    25681 gcacaataaa cgccacacaa aaatgccgtc tgaaaccatt tcgtttcaga cggcattttt
    25741 ttatctctaa ccgtttactc gccgcgtttt tccaaagcgg ctacggcagg cagctctttg
    25801 ccttccaaga attcgaggaa cgcgccacct ccggtggaga tgtagccgat ttgttcggta
    25861 acgccgaatt tggcaatcgc cgccagcgtg tcgccgccgc ccgcaatcga gaacgctttg
    25921 ctttgggcaa tggcttcggc aagggctttc gtaccgcctg cgaactggtc aaactcaaac
    25981 acgccgaccg gcccgttcca tacgaccgta ccggcggctt taagcaaatc ggcaagcgcg
    26041 gcggcagatt tcgggccgat gtccaaaatc atctcgtctt cggcaacgtc ggcaatgtct
    26101 ttcacgaccg cttcctcatc agcggcaaag gctttggcaa cgacgacatc ggtcggcagc
    26161 ggcacagaac cgcctttggc cgccattttc gccataattt ttttggattc ttccaccaaa
    26221 tcgtgttccg ccaaagattt gccgatggct ttaccttccg ccaacaggaa ggtgttggcg
    26281 ataccgccgc cgacgatgag ttggtcgact ttgtccgcca gcgattcgag gatggtcagc
    26341 ttggtggaca ctttgctgcc ggcaacgatg gcaaccatcg ggcgcgcggg ctgtttcaag
    26401 gctttgccca aagcgtcgag ttcgcccgcc atcaatacgc cggcgcaggc aacgggagcg
    26461 gcttgggcga cggcttcggt cgaggcttgg gcgcggtgcg cggtgccgaa cgcgtcattg
    26521 acgaacacgt cgcacaaaga agcgtaggct ttgcccagtt ccaaatcgtt tttcttctcg
    26581 cctttgttga tacgcacgtt ttgcagcatc acgacatcgc ccgcgttcaa agccggtttg
    26641 ttttcacgcc agtcgttcaa tactttcacg tctttgccca acagaccgcc caagtgcgcg
    26701 gcaacgggcg cgacatcgtc ttcggaatgg aattcgcctt cggtcgggcg acccaagtgg
    26761 gtcatcacga tgacggacgc gccgttgtcc aagcagtatt tgatggacgc aagtgaggcg
    26821 cggatacggg tgtcgtcgct gattttgccg tctttgaacg gcacgttcat atcggcgcga
    26881 atgaggacgg ttttgccctg cacgttttgt tcggtcagtt ttaaaaatgc cataatcagt
    26941 ccttttcaat cagtgtttgc gatacagaaa caattgatgc cgtctgaagg cttcagacgg
    27001 catcgcaacc cgatcagccg gatacgcgct cgattttcgc gccgacgctg ccgagttttt
    27061 tttcaatatt ttcataaccg cgatccaagt ggtaaatctg ttcgaccacg gtttcgccgc
    27121 gcgccgccaa accggcgata acgaggcttg cggacgcacg caaatccgtc gccttgacga
    27181 ctgcgccgga aagccgttcc acaccctgca caaatgccgt attgccctcg gttgtaatgt
    27241 tcgcccccat ccggttcaac tcggggacgt gcataaagcg gttttcaaaa atcgtttcca
    27301 ccacgcggca gcttccctcc gccacggcat tcaatgccat aaactgcgcc tgcatatccg
    27361 tggggaagcc ggggtggacg accgtgcgga tgtccaccgc cttcggacgc tgccgcatat
    27421 cgatggcgat ccaatcgtcg cccgcctcaa tcaccgcacc tgcctcaacc agtttgtcca
    27481 acaccacttc catcgttttc ggcgcagcat tccgcaaaac caccctgccg ccggttatcg
    27541 ccaccgcaca caggaacgtc cccgcttcaa tccggtcggg gacaacgctg tgttcgcagc
    27601 cgtgcagctc gtccacacct tccacaatca ttgtggacgt accgatgccg ctgattttcg
    27661 cgcccatttt gaccaggcat tccgccaaat cgaccacttc aggctcgatg gcgcagtttt
    27721 ccaaaaccgt cgtaccttcc gccagcgtcg ccgccatcag caggttttcc gtgccgccga
    27781 cggtaacgac atccattgcc acacgcgtgc ctttaagctt acccttggct ttgacgtaac
    27841 cgtgttcgat aacaatctca gcacccatcg cttctaagcc tttcaaatgc tggtcgacag
    27901 ggcgcgaacc gatggcgcag ccgcccggca ggctgacttg cgcctcgccg aaacgcgcca
    27961 gcgtcgggcc aagcaccaaa atcgaggcgc gcatcgtccg gaccaattcg taaggggcgc
    28021 aggtgttgtt taccgtacca ccgttgattt caaattcact gatattgtcg gtcaggacgc
    28081 gcgcgcccat cccctgaagc agcttttgtg tggttttcac atctgccagc atagggacgt
    28141 ttttcaggcg caacgtaccc gatgtcagca aacccgcgca catcagcggc aatgccgcgt
    28201 ttttcgcgcc cgagaccgtt atttccccgt tgagcgggcc gtttgcggag attttcagtt
    28261 tgtccacgtt tgttctttcc tagtgggtac ttgtaatatt tcaatactcg ggacaacgca
    28321 taaagcatca cccgatgaag gttacagagg cggaattata agggattttc gggaaaaata
    28381 cggaagccgc accaaagaat ttgacgaaat gccgcgcttt ccgaacaagg attgtcggaa
    28441 gacaaaaaaa gccgagtttt gaaaactcag ctttttttgt tttatctggt gggtcgtgag
    28501 cgattcgaac gctcgaccaa cggattaaaa gtccgctgct ctaccgactg agctaacgac
    28561 ccgataagct cgaaattcta tacatcaagc ctgatgctgt caaccatttt gtcggcgctc
    28621 atacggcatt ttatttatcg gactgttttt tcgtataaat taacgaggtc agtatcgatg
    28681 cacccaacgc gccgaacacg accgacagcg aaacggaaat cgggatatgc acccaatgca
    28741 ttaccagcat tttcacaccg ataaaaccca acacgaatgc caagccgtat ttcaggaaga
    28801 taaagcgttc cgccacatcc gccagcagga aatacatcgc ccgcaagccc aaaatagcga
    28861 aaatattgga agtcagcacg ataaacggat cggtggtaac ggcaaagacg gcggggatgc
    28921 tgtccacggc aaacacgaca tcgctcaatt caatcatgac cagcaccaaa aacagcggcg
    28981 tggcgatttt tttaccgttt tcgacagtaa aaaatttctc gccgtgaaat tccgtgccga
    29041 ccggaacgac tttcttgacg gcattcagca gcctgctgtt tgccaaatcc ccttcctcat
    29101 cgccttcggg cttcatcatg tgtataccag tatagagcag gaacgcgccg aacagataca
    29161 gaatccactc gaactgctga accagtgccg cgccgacgaa aatcatgaca gtgcgcaata
    29221 ccaatgcgcc caatacgccg tacagcagca cgcggtgctg aaactgcggt gcgactttga
    29281 agtagccgaa tatcatcagg aacacgaaaa tattgtcgac tgccaacgat ttttccaaaa
    29341 tgtagccggt aaagaattcc aatacttttt cttttgcgac tgccgcgccg tagccgggat
    29401 tgccggcgag tttgaaatac agccagcctg cgaacaggca ggatacggca acccacaagc
    29461 cgctccatgc caaggcttct ttgacgccga ctttatggct gctgtttttc ttcagcgaaa
    29521 acatatccaa ggcaatcatg accagcactg ccgcaaaaaa aacgccgtaa aacaacggcg
    29581 acccgatgcc gggatattct gtcatggttc aatctcctga tttgaaatgt agttgtgtta
    29641 ccagctgata taaaacatcg cttttgccaa aaagacaatc agcagcatat gggtaaagac
    29701 gacggtgtgt atgtatttcg accagccgac ggtcagtgtg gaacgcgcca ttttgacgac
    29761 ggcgatggcg aagtgcgcca acacgctgaa cgccaacagg attttcagcg tcagcatcgt
    29821 accgaaggaa gtggcaaacg gttcgcccaa tatagaaaga tagcggtttg ccgccatcac
    29881 gatgccgctg gcgaacagca gtccgaccac aaacggcatc accctgacgg cgcggtaaga
    29941 cattgccttt tccacttcgc gccgcgcctc gcacgacacc cgtcccgtat gcaggacgga
    30001 caaaaccagc acttcaaaaa acacgccgcc gacaaaggca atggcgcaat acaggtggac
    30061 gatgtgcgcg acggcataaa tactcatacg atgctccaac cggaaaactc ggatacggat
    30121 tgtatcacta tcgtccccga tgtccgcata ccgcttcccg caccgcctcg gcgattctcg
    30181 cgcccgctcc gcgatgttgt gcgataaagc cgtccacgcg tgcctgcatc tgcattccgc
    30241 ccccctcgga cgataaggct ttttcaacgg ctgcccgcca cgcgtccgcc gattcgactt
    30301 gaaccgccgc acccgatgcc aaggcgtacc ggcaggcttc agaaaaattg taagtcgaaa
    30361 agccgaatat cgtcggaacg ccgcaggaaa gcggttcgat aatgttctga cagcccgaat
    30421 cgaccagact gccgccgaca aaagcgacat cggcgcacag gtaatacgca cacagctcgc
    30481 ccatactgtc gcctatccac acctgcgtat cgggttcgac cggcaaaccg tcgctgcgcc
    30541 gctgaacctt aaacccgaag cgttttgccg tttcaaatac cgtctgaaaa tgctcaggat
    30601 ggcgcggcac gacgaccagc agggcatcgc cgcgatattg ttgccacgcc gccagcagtt
    30661 tttccgcctc gtcttcaccc cgataaacgc gcgtgctgcc gcacacggca accggccggt
    30721 ctccgatgcg tttttcaaac tgccccgcca gcgttttcat ctgttccgac ggcatcaggt
    30781 cgtatttggt attgccgcac acctgcacgg atgccgcgcc caatttcgcc aaccgcgccg
    30841 catccgcctc cgtctgcgcc agacaacccg tcagcgaagc ggcggcagga cggatcaggc
    30901 ggcggacttt cagataaccg tttagcgatt tttccgacag ccgcgcattc gccaaaaaca
    30961 gcggaacgcc cgatttccgg cactccgtca tcaggttggg ccagatttcg gtttccatca
    31021 aaatgccgaa catcgggcgg tgttcgcgca aaaactgccg tacccacgtt tttttgtcat
    31081 acggaagata acggcattgt gcatcaggaa acagaacttg cgcggtttcc cgtcccgtcg
    31141 gggtcatctg agtcatcagc agcggcgcat cgggaaaacg ctgccgcaac tcgcgtatca
    31201 agggctgggc ggcacgcgtt tctccgaccg aaacggcgtg tatccaaacc gcgccggtaa
    31261 cgggattcgg atacggcttg ccgaaacgct cgtcccgatg cgcccgatat gcaggggcac
    31321 ttccggagcg tttgtccaaa taacgccgta tccatatcgg cgcaagcagc cacaatgcat
    31381 cataaagcca ttggaacatc tttctatttc ctgcaaaaca aatgccgtcc gaacggttcg
    31441 gacggcattt cggcaacgga atcaaatatc gtaggttgtc gaagcggtat ctccgccctt
    31501 gcccgtccag ttggtatgga aaaactcgcc gcgcggtttg tcggtgcgct cgtaagtgtg
    31561 cgcgccgaag tagtcgcgct gtgcctgcaa gaggttggca ggcagacgtt cggtcgtgta
    31621 gccgtccaag aacgtaatcg ccgaagccat gcagggcata gggatgccgc attcgaccgc
    31681 cttggcaacc accttgcgcc atgccggcag gcagttttcc aaaatatttt tgaaatacgg
    31741 atccgcaccc aagaacacca aatcgggatt gttttcatac gcgtcgcgga tattgcttaa
    31801 gaatgcgctg cggatgatgc acccctcgcg ccacagcagc gcagtgttgc cgtagtccaa
    31861 atcccagccg tagctttcgc ccgcttcgcg gatcagcatg aagccttgtg cgtaggaaat
    31921 gattttagat gcaagcaggg cctgtctcaa cgcctcaacc cattcttgtt tgccgccttc
    31981 gacgggcgta acggttcggg cgaatagctt gccggtctgc acgcgctgtt ctttgaacga
    32041 cgaaacgcag cgggcgaata ccgcttcgga aatcagcgtc aacggaatac ccaaatccaa
    32101 agcattgatg cccgtccatt tgcccgtgcc tttttgccct gccgtatcga ggattttctc
    32161 gaccagcggt tcgccgcctt cgtccttata gcccaaaatt gccgctgtga tttcaatcag
    32221 ataagaatcc agctcggttt tgttccactc ggcaaacacg cggtgcattt cgtcgtaaga
    32281 cagccccaag ccgtctttca tgaactggta cgcttcgcaa atcaactgca tatcgccgta
    32341 ttcgatgccg ttatgcacca ttttgacaaa atgccccgcg ccgtccctgc cgacccagtc
    32401 gcaacacggt tcgccctgcg gcgttttggc ggcaatcgcc tgaaaaatcg gtttgacggc
    32461 ttcccaagcg cgctcatctc cgcccggcat gatagacggg ccgtgccgcg cgccttcttc
    32521 gccgccggat acgcccgcgc cgacaaacaa aatccctttt tcggcaaggt aatgtgtccg
    32581 ccgtgtcgtg tcggggtaat tggcattgcc gccgtcgata atgatgtcgc cttcttccaa
    32641 caacggaagc agttgttcga taaagtcgtc aaccaccgaa cctgcgcgaa ccatcatcat
    32701 gatttttctc ggttttgcca gcttatcgac caagtcttgc agggaatacg cgccgacaat
    32761 atccgttccc ttagccgcgc cgtttaaaaa ttcgtccacc ttaccgattg ttcggttgta
    32821 ggcgacaacc ttaaatccgc aatcgttcat attcaaaatc aggttttgcc ccataaccgc
    32881 caaaccgatt acaccaatat cgcctttcat tgcaggaagc tccgttatag atttaattta
    32941 tcgaccgcaa ctctacctga tttacacttg tttaacaatc cttaactttt taattttttg
    33001 aaaagatatc tttacgcttt cccgtgccgt ttccctgaag gcttataaat aaaatataaa
    33061 atttaaataa aaaaacgatg attatattga taggagaaat tttctgtggg taactttttt
    33121 ttattttaaa aatcattggg atttccgttt taaaagggtg tcggtaaggc ggattccctt
    33181 ttgtgcatac ctgtggattg tttttcatga agaatagttt ttgtggacag tttgcttgtt
    33241 gtgcagatgg cattccgctt ttctttaccg aatggctgcc gatgccttta agaacgggaa
    33301 tgttgtggag atttgagagg gaagtgtgtt tggaacttgt aggaatgaga atgtgtcgat
    33361 acaaatatct tttttctgca tattggcaga gtacgcatcc gaatttgtgt ataagtggtg
    33421 gaaaaaatga gatttgcggg taaatctcac aatatttcag tcagataact ttggattgct
    33481 tgtgtataag taaagttttg gatggggata cgtaacggaa acctgtaccg cgtcattccc
    33541 acgaacctac atcccgtcat tcccacgaaa gtgggaatga tgaaatttta agtttgagga
    33601 atttatcgga aaaaacagaa accgctctac cgtcattccc gcgcaggcgg gaatctagac
    33661 cttagaacaa cagtaatatt caaagattat ctgaaagtcc gagattctgg attcccactt
    33721 tcgtgggaat gacgggattt gagattgcgg catttatcgg aaaaaacaga aaccgctccg
    33781 ccgtcattcc cgcgcaggcg ggaatccaga ccttagaaca acagtaatat tcaaagatta
    33841 tctgaaagtc cgggattcta gattcccact ttcgtgggaa tgacggcatc agtctgccgt
    33901 ttacagcacg gtttctttag attttacgtt ctagattccc gcctgcgcgg gaatgacgaa
    33961 tccatccata cggaaacctg caccacgtca ttcctacgaa cctacatccc gtcattccca
    34021 caaaaacag
//
LOCUS       DAXIDM010000008        32682 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000008 DAXIDM010000000
VERSION     DAXIDM010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 32682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32682
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.008"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..223
                     /locus_tag="ACFOAE_000318"
     CDS             <1..223
                     /locus_tag="ACFOAE_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003699853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883886.1"
                     /translation="FQTDAPGFQYARARCSLVRRHRRQRPIFRGTPVSGVFKGSAVRC
                     FPAARLQTASPARPLDKACAWGDNGVLLF"
     gene            234..512
                     /locus_tag="ACFOAE_000319"
     CDS             234..512
                     /locus_tag="ACFOAE_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883887.1"
                     /translation="MSRNLLVRWLVVCLIPLATLAVFVANPPEDKPQHLINGIILACE
                     ATFLFKFVLFDTIKHHLKQEFDLKRQTMLLFIPIVLLVVYLFHYFGAF"
     gene            531..1679
                     /gene="earP"
                     /locus_tag="ACFOAE_000320"
     CDS             531..1679
                     /gene="earP"
                     /locus_tag="ACFOAE_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0106361 - protein-arginine
                     rhamnosyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P maturation arginine
                     rhamnosyltransferase EarP"
                     /protein_id="HFC6883888.1"
                     /translation="MNTPPFVCWIFCKVIDNFGDIGVSWRLARVLHRELGWQVHLWTD
                     DVSALRALCPDLPDVPCVHQDIHVRTWHSDAADIDTAPVPDVVIETFACDLPENVLHI
                     IRRHKPLWLNWEYLSAEESNERLHLMPSPQEGVQKYFWFMGFSEKSGGLIRERDYCEA
                     VRFDSEALRQRLMLPEKNAPEWLLFGYRSDVWAKWLEMWRQAGSPMTLLLAGTQIIDS
                     LKQSGVIPQDALQNDGDVFQTASVRLVKIPFVPQQDFDKLLHLADCAVIRGEDSFVRA
                     QLAGKPFFWHIYPQDENVHLDKLHAFWDKAHGFYTPETVSAHRRLSDDLNGGGALSAT
                     QRLECWQILQQHQNGWRQGAEDWSRYLFGQPSASEKLAAFVSKHQKIR"
     gene            1722..2282
                     /gene="efp"
                     /locus_tag="ACFOAE_000321"
     CDS             1722..2282
                     /gene="efp"
                     /locus_tag="ACFOAE_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFC6883889.1"
                     /translation="MKTAQELRAGNVFMVGNDPMVVQKTEYIKGGRSSAKVSMKLKNL
                     LTGAASETIYKADDKFDVVILSRKNCTYSYFADPMYVFMDEEFNQYEIEADNIGDALK
                     FIVDGMEDQCEVTFYEGNPISVELPTIIVREVEYTEPAVKGDTSGKVMKTARLVGGTE
                     IQVMSYIENGDKIEIDTRTGEFRKRA"
     gene            complement(2332..3177)
                     /locus_tag="ACFOAE_000322"
     CDS             complement(2332..3177)
                     /locus_tag="ACFOAE_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NMB0938 family lipoprotein"
                     /protein_id="HFC6883890.1"
                     /translation="MKNKTSSLLLWLAAMMLTACSPSKEDKTKENGASAASSTASAAS
                     SSAPQTDLQPAASAPDNVKQAESVPPSNCTDLHPATGIDDLMQQIAEHIDSDCLFALS
                     HHELETRFGLPGGGYDNIQRLLFPDIRPEDPDYHQKIILAIEDLRYGKRTISRQAQDA
                     LMEQERRLREATLLLIQGSQETRGQGEEPKRTRYFEVSATPAYSSRHNNGLGGNFQYI
                     GQLPGYLKIHGEMLENQSLFRLSNRERNPDKPFLDIHFDENGKITRIVVYEKNIYFNP
                     NLGRR"
     gene            complement(3294..3875)
                     /gene="metW"
                     /locus_tag="ACFOAE_000323"
     CDS             complement(3294..3875)
                     /gene="metW"
                     /locus_tag="ACFOAE_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine biosynthesis protein MetW"
                     /protein_id="HFC6883891.1"
                     /translation="MNLRDDLQLIYDRIPEGSRVLDLGCGDGELLAALVEHKKCSGYG
                     IEIDTDSVIAAMSRGVNVIQADLEEGLTAFNDQSFDVIVLSQTIQAMQNTEKILRCLM
                     RVAKQAIVSFPNFGYWRNRVQIALGGHMPVSERMPYHWYDTPNIHWCTLKDFDLLCAK
                     NNIRVLERAVMTGNRQVKHFPNLLGSLAFYRVG"
     gene            complement(3872..5011)
                     /locus_tag="ACFOAE_000324"
     CDS             complement(3872..5011)
                     /locus_tag="ACFOAE_000324"
                     /EC_number="2.3.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-acetyltransferase"
                     /protein_id="HFC6883892.1"
                     /translation="MSQNASVGIVMPQKIPFEMPLVLENGKTLPRFDLMIETYGELNA
                     EKNNAVLICHALSGNHHVAGRHSAEDKYTGWWDNMVGPGKPIDTERFFVVGLNNLGGC
                     DGSSGPLSINPETGREYGADFPLVTVKDWVKSQAALADYLGIGQWAAVVGGSLGGMQA
                     LQWAISYPERVRHALVIASAPKLSTQNIAFNDVARQAILTDPDFNEGHYRSHNTVPAR
                     GLRIARMMGHITYLAEDGLGKKFGRDLRSNGYQYGYGVEFEVESYLRYQGDKFVGRFD
                     ANTYLLMTKALDYFDPAADFGNSLTRAVQDVQAKFFVASFSTDWRFAPERSHELVKAL
                     IAAQKSVQYIEVKSAHGHDAFLMEDEAYMRAVAAYMNNVYKECQQ"
     gene            5161..5361
                     /locus_tag="ACFOAE_000325"
     CDS             5161..5361
                     /locus_tag="ACFOAE_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883893.1"
                     /translation="MIGRLFRIFFFFALAALIINRLFSRRQKRALREVAEISAWVLLG
                     AAAAMLFWYLFMLYFKHIPDSY"
     gene            complement(5573..5698)
                     /gene="ykgO"
                     /locus_tag="ACFOAE_000326"
     CDS             complement(5573..5698)
                     /gene="ykgO"
                     /locus_tag="ACFOAE_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HFC6883894.1"
                     /translation="MQVLSSLKTAKQRHRDCQIVRRRGKVYVICKSNPRFKARQR"
     gene            complement(5698..5973)
                     /locus_tag="ACFOAE_000327"
     CDS             complement(5698..5973)
                     /locus_tag="ACFOAE_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFC6883895.1"
                     /translation="MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKE
                     YPLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK"
     gene            6174..7052
                     /gene="metF"
                     /locus_tag="ACFOAE_000328"
     CDS             6174..7052
                     /gene="metF"
                     /locus_tag="ACFOAE_000328"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HFC6883896.1"
                     /translation="MNYAKEINALNNSLSDLKGDINVSFEFFPPKNEQMETMLWDSIH
                     RLQTLHPKFVSVTYGANSGERDRTHGIVKRIKQETGLEAAPHLTGIDASPDELRQIAK
                     DYWDSGIRRIVALRGDEPPGYEKKPFYAEDLVKLLRSVADFDISVAAYPEVHPEAKSA
                     QADLINLKRKIDAGANHVITQFFFDVERYLRFRDRCVMLGIDVEIVPGILPVTNFKQL
                     GKMAQVTNVKIPSWLSQMYEGLDDDQGTRNLVAASIAIDMVKVLSREGVKDFHFYTLN
                     RSELTYAICHILGVRP"
     gene            7190..9466
                     /gene="metE"
                     /locus_tag="ACFOAE_000329"
     CDS             7190..9466
                     /gene="metE"
                     /locus_tag="ACFOAE_000329"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFC6883897.1"
                     /translation="MTTLHFSGFPRVGAFRELKFAQEKYWRKEISEQELLAVAKDLRE
                     KNWKHQAAANADYVAVGDFTFYDHILDLQVATGAIPARFGFDSQNLSLEQFFQLARGN
                     KDQFAIEMTKWFDTNYHYLVPEFHADTEFKANAKHYVQQLQEAQALGLKAKPTVVGPL
                     TFLWVGKEKGAVEFDRLSLLPKLLPVYVEILTELAAAGAEWIQIDEPALAVDLPQAWL
                     DAYQDVYATLSQVNAKILLSTYFGSVAAHAGRLKALPVAGLHIDLVRAPEQLDAFADY
                     GKVLSAGVIDGRNIWRANLNNVLATLEPLKAKLGDRLWISSSCSLLHTPYDLSVEEKL
                     KVNKPALFSWLAFTLQKTQELRVLKTALNQGREAVAAELADSQAAADSRANSTEIHRA
                     EVAKRLADLPADADQRKSPFAERIKAQQAWLNLPLLPTTNIGSFPQTTEIRQARAAFK
                     KGELSDADYEAAMKKEIALVIEEQEKLNLDVLVHGEAERNDMVEYFGELLEGFAFTQY
                     GWVQSYGSRCVKPPVIYGDVSRPNAMTVAWSTYAQTLTKRPMKGMLTGPVTILQWSFV
                     RNDIPRSTVCKQIALALNDEVLDLEKAGIKVIQIDEPAIREGLPLKRADWDAYLAWAS
                     EAFRLSSTGCEDSTQIHTHMCYSEFNDILPAIASMDADVITIETSRSDMELLTAFGEF
                     KYPNDIGPGVYDIHSPRVPTEAEVEHLLRKAIEVVPFERLWVNPDCGLKTRGWKETLE
                     QLQVMMNVTRKLRAELAK"
     gene            9745..10482
                     /locus_tag="ACFOAE_000330"
     CDS             9745..10482
                     /locus_tag="ACFOAE_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HFC6883898.1"
                     /translation="MALQDRTGQKVPSVVFRTRVGDTWKDVSTDDLFKGKKVVVFSLP
                     GAFTPTCSSSHLPRYNELFGAFKENGVDAIYCVSVNDTFVMNAWAAEEESDNIYMIPD
                     GNGEFTEGMGMLVGKEDLGFGKRSWRYSMLVNDGVVEKMFIEPEELGDPFKVSDADTM
                     LQFVAPDWKAQESVAIFTKPGCQFCAKAKQALQDKGLSYEEIVLGKDATVTSVRAITG
                     KMTAPQVFIGGKYIGGSEDLEACLAKN"
     gene            10731..12134
                     /locus_tag="ACFOAE_000331"
     CDS             10731..12134
                     /locus_tag="ACFOAE_000331"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC6883899.1"
                     /translation="MKKIQADVVVIGGGTAGMGAFRNARLHSDNVYLIENNVFGTTCA
                     RVGCMPSKLLIAAAEARHHALHTDPFGVHLDKDSIVVNGEEVMQRVKSERDRFVGFVV
                     ADVEEWPADKRIMGSAKFIDEHTVQIDEHTQITAKSFVIATGSRPVILPQWQSLGNRL
                     IINDDVFSWDTLPKRVAVFGPGVIGLELGQALHRLGVKVEIFGLGGIIGGISDPVVSD
                     EAKAVFGEELKLHLDAKTEVKLDADGNVEVHWEQDGEKGVFVAEYMLAAVGRRPNVDN
                     IGLENINIEKDARGVPVADPLTMQTSIPHIFIAGDASNQLPLLHEAADQGKIAGDNAG
                     RYPNIGGGLRRSTIGVVFTSPQIGFVGLKYAQVAAQYQADEFVIGEVSFKNQGRSRVM
                     LVNKGHMRLYAEKATGRFIGAEIVGPAAEHLAHLLAWAHQMKMTVPQMLDMPFYHPVI
                     EEGLRTALRDADAKLKA"
     gene            12413..12790
                     /gene="sdhC"
                     /locus_tag="ACFOAE_000332"
     CDS             12413..12790
                     /gene="sdhC"
                     /locus_tag="ACFOAE_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045273 - respiratory chain complex II
                     (succinate dehydrogenase) [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, cytochrome b556
                     subunit"
                     /protein_id="HFC6883900.1"
                     /translation="MSAKPRPVYLDLPNIRLPIPGIVSILHRISGVGLFIMLPFLLYF
                     LSGTLSQESAFETYRAIVSHPLVKLVLIGVLWAYLHHSLAGIRFLFLDAHKGLELNTA
                     RNTAKAVFASALVLTVVLGALLW"
     gene            12784..13125
                     /gene="sdhD"
                     /locus_tag="ACFOAE_000333"
     CDS             12784..13125
                     /gene="sdhD"
                     /locus_tag="ACFOAE_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0045273 - respiratory chain complex II
                     (succinate dehydrogenase) [Evidence IEA];
                     GO_function: GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase, hydrophobic membrane
                     anchor protein"
                     /protein_id="HFC6883901.1"
                     /translation="MVERKLTGAHYGLRDWAMQRATAVIMLIYTVALLVVLFSLPKEY
                     SAWQAFFSQTWVKVFTQVSFIAVFLHAWVGIRDLWMDYIKPFGVRLFLQVATIVWLVG
                     CLVYSIKVIWG"
     gene            13128..14891
                     /gene="sdhA"
                     /locus_tag="ACFOAE_000334"
     CDS             13128..14891
                     /gene="sdhA"
                     /locus_tag="ACFOAE_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HFC6883902.1"
                     /translation="MGFPVRKFDAVIVGGGGAGLRAALQLSKSGLNCAVLSKVFPTRS
                     HTVAAQGGISASLGNVQEDRWDWHMYDTVKGSDWLGDQDAIEFMCRAAPEAVIELEHM
                     GMPFDRVESGKIYQRPFGGHTAEHGKRAVERACAVADRTGHAMLHTLYQQNVRANTQF
                     FVEWTAQDLIRDENGDVVGVTAMEMETGEVYIFHAKAVMFATGGGGRIYASSTNAYMN
                     TGDGLGICARAGIPLEDMEFWQFHPTGVAGAGVLITEGVRGEGGILLNADGERFMERY
                     APTVKDLASRDVVSRAMAMEIYEGRGCGKNKDHVLLKIDHIGAEKIMEKLPGIREISI
                     QFAGIDPIKDPIPVVPTTHYMMGGIPTNYHGEVVVPQGDEYEVPVKGLYAAGECACAS
                     VHGANRLGTNSLLDLVVFGKAAGDSMIKFIKEQSDWKPLPADAGELTRQRIERLDNQT
                     DGENVDALRRELQRSVQLHAGVFRTDEILSKGVREVMAIAERVKRTEIKDKSKVWNTA
                     RIEALELDNLIEVAKATLVSAEARKESRGAHASDDHPERDDENWMKHTLYHSDTNTLS
                     YKPVHTKPLSVEYIKPAKRVY"
     gene            15011..15718
                     /locus_tag="ACFOAE_000335"
     CDS             15011..15718
                     /locus_tag="ACFOAE_000335"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008177 - succinate dehydrogenase
                     (quinone) activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HFC6883903.1"
                     /translation="MEKMSFEIYRYNPDVDAKPYMQRYELELEPTDVKLLDALVRLKA
                     QDDTLSFRRSCREGICGSDGMNINGKNGLACLTDLRGLKQPVKIRPLPGLPVIRDLIV
                     DMTQFFKQYHSVKPYVVNDNPIDADKERLQTQEERKELDGLYECILCACCSTACPSFW
                     WNPDKFVGPSGLLNAYRFIADSRDTITNERLDNLNDPYRLFRCHTIMNCVDVCPKHLN
                     PTRAIGKIKEIMLKRAV"
     gene            15722..15970
                     /locus_tag="ACFOAE_000336"
     CDS             15722..15970
                     /locus_tag="ACFOAE_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase assembly factor 2"
                     /protein_id="HFC6883904.1"
                     /translation="MMVFDDIAKRKIRFQTRRGLLELDLIFGRFMEKEFEHLSDKELS
                     EFSEILEFQDQELLALINGHSETDKGHLIPMLEKIRRA"
     gene            16082..17365
                     /gene="gltA"
                     /locus_tag="ACFOAE_000337"
     CDS             16082..17365
                     /gene="gltA"
                     /locus_tag="ACFOAE_000337"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004108 - citrate (Si)-synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HFC6883905.1"
                     /translation="MSKSIKLNVPGQAGLELPVLEASIGHDVVDIRGLTKNTGLFSFD
                     PGFVSTASCESKITYIDGDQGLLYYRGYPIEQLAEKSDYLEVCYLLIYGELPTPEQKA
                     EFDNTVRRHTMVHEQLTWFFRGFRRDAHPMAMMVGVVGALSAFYQDSLDISNPEHRKI
                     AIYRLISKIPTIAAMCYRYSNGLPFNYPKNNLSYSENFLHMMFATPCEDYKPNPVLAR
                     ALDRIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGASHGGANEAVLKML
                     DEIGDVSNVAAYMEGVKQRKYRLMGFGHRVYRNMDPRASIMRETCYEVLKELGLEDSP
                     KFKLAMELEQIALKDPFFIERKLYPNVDFYSGIVLSALGIPTEMFTVIFALSRSVGWI
                     SHWHEMISDPSLKIGRPRQLYTGSERRDYVPAGER"
     gene            17570..20398
                     /locus_tag="ACFOAE_000338"
     CDS             17570..20398
                     /locus_tag="ACFOAE_000338"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004591 - oxoglutarate dehydrogenase
                     (succinyl-transferring) activity [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HFC6883906.1"
                     /translation="MMDEKLNFSYLFGSNAPYIEELYEAFLENPDAVDEKWKQYFTDL
                     SKQPGTVAVDVAHTPIRESFVTLAKKKIASAVAGGADEAMLKKQVSVLRLISAYRIQG
                     VGAAQLDPLKRIPPRDIEALDPKFHGLSDADMALQFNMGEGDFANRGKLPLSQIISNL
                     KQTYCGHIALEYIYIPNTEERRWVRNYFESVLSTPHYNADQKRRILKEMTAAETLERY
                     LHTKYVGQKRFGVEGGESAIAGLNYLIQNAGKDGVEEVIIGMAHRGRLNVLVNILGKK
                     PGDLFAEFEGRAEIKLPSGDVKYHMGFSSDIATPHGPMHVSLAFNPSHLEIVNPVVEG
                     SARAKQKRLGENGRDKVLPVLIHGDSAFIGLGVNQATFNLSKTRGYTTGGTVHIVINN
                     QIGFTTSDIRDTRSTVHCTDIAKMVSAPVIHVNGDDPERVCFAIQAALDYRKKFHKDI
                     VIDVVCYRKWGHNEGDDPTLTQPMMYKKVSQHPGARALYTEQLIAEGVVTQAEADGYI
                     QAYRDALDKGEHVEQTTLSNFQRTQIDWSKYQGKDWREHIETGLPAADIERLTEKFTA
                     VPEGFALHPTAKRVIEARKAMASGKQAIDWGMAETLAYASLVTKGHGVRISGEDSGRG
                     TFSHRHAVLHDQNREKWDDGTYVPLRHMGEGMGEFLVIDSILNEEAVMAFEYGFACSA
                     PDKLTIWEAQFGDFANGAQVTIDQFLSSGETKWGRLCGLTTILPHGYDGQGPEHSSAR
                     VERWLQLCSENNMQVIMPSEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPL
                     ENFTEGSTFRPVIGDTAERASNDSVKRVVLCAGQVYYDLEAGRAERKLEDDVAIVRVE
                     QLYPFPYDEVKAELAKYPNAKSVVWAQEEPKNQGAFYQIRHRIEDVISEEQKLSYAGR
                     PSSASPAVGYSSKHIAQLKQLVEDALAL"
     gene            20498..21679
                     /gene="odhB"
                     /locus_tag="ACFOAE_000339"
     CDS             20498..21679
                     /gene="odhB"
                     /locus_tag="ACFOAE_000339"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA];
                     GO_function: GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HFC6883907.1"
                     /translation="MIIDVKVPMLSESVSEGTLLEWKKKVGEAIARDEILIDIETDKV
                     VLEVPSPQAGVLVEIVAQDGETVVADQVLARIDTAATAAAEAPAAAPAEAAPAAAPAA
                     AQNNAAMPAAAKLAAETGVDVNALQGSGRDGRVLKEDVQNAAAKPAAAAAPAVTLPAG
                     ARPEERVPMSRLRARVAERLLASQQENAILTTFNEVNMKPIMDLRAKYKEKFEKEHGV
                     KLGFMSFFVKAAVAALKKYPVVNASVDGKDIVYHGYFDIGIAIGSPRGLVVPILRDAD
                     QMSIADIEQAIVDYAKKAKDGKIAIEDLTGGTFSITNGGTFGSMMSTPIINPPQSAIL
                     GMHATKERAVVENGQVVVRPMMYLALSYDHRIIDGREAVLTLVAIKDALEDPARLLLD
                     L"
     gene            complement(21731..21847)
                     /locus_tag="ACFOAE_000340"
                     /pseudo
     CDS             complement(21731..21847)
                     /locus_tag="ACFOAE_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            22044..23477
                     /gene="lpdA"
                     /locus_tag="ACFOAE_000341"
     CDS             22044..23477
                     /gene="lpdA"
                     /locus_tag="ACFOAE_000341"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC6883908.1"
                     /translation="MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPA
                     LGGTCLNVGCIPSKALLQSSEHFHAAQHDFAEHGITVGDVKFDAAKMIERKDAIVTKL
                     TGGVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRP
                     LPQVAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGAEVTILEAAPT
                     FLAAADQQIAKEAFKYFTKEQGLSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFD
                     KLIVAIGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVWAIGDVVRGPMLAHK
                     ASDEGVAVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGF
                     GANGRALAMGKAKGTVKVLADAKTDRILGVHMIGPVVSELVIEGVTALEFFASSEDIA
                     RIIHAHPTLSEVVHEAALAADKRALHG"
     gene            23602..23889
                     /locus_tag="ACFOAE_000342"
     CDS             23602..23889
                     /locus_tag="ACFOAE_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883909.1"
                     /translation="MNKEIVGIFFIPMGIISMCMAALWQMYVMMTETYTLNRFKDKEL
                     VWRVALLFISFSLAVYLLCPNSRKKGIVFFILGGGGAAMYLLARMWLPFSK"
     gene            23985..25154
                     /gene="sucC"
                     /locus_tag="ACFOAE_000343"
                     /pseudo
     CDS             23985..25154
                     /gene="sucC"
                     /locus_tag="ACFOAE_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686088.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
     gene            25165..26055
                     /gene="sucD"
                     /locus_tag="ACFOAE_000344"
     CDS             25165..26055
                     /gene="sucD"
                     /locus_tag="ACFOAE_000344"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016655272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HFC6883910.1"
                     /translation="MSVLINKDTKVLVQGFTGKNGTFHSEQALAYGTKVVGGVTPGKG
                     GQTHLNLPVFNTMKEAVKETGADASVIYVPAPFVLDSIVEAVDSGVGLVVVITEGVPT
                     LDMLKAKRYLETNGNGTRLVGPNCPGVITPGECKIGIMPGHIHTPGRIGIISRSGTLT
                     YEAVAQTTKLGLGQSTCIGIGGDPIPGMNQIDALKLFQEDPDTDAIIMIGEIGGTAEE
                     EAAEYIQSNVTKPVVGYIAGVTAPKGKRMGHAGAIISGGKGTAEEKFAAFEKAGIAYT
                     RSPAELGTTMLEVLKAKGLA"
     gene            complement(26295..26618)
                     /locus_tag="ACFOAE_000345"
                     /pseudo
     CDS             complement(26295..26618)
                     /locus_tag="ACFOAE_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258178.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(26590..26733)
                     /locus_tag="ACFOAE_000346"
     CDS             complement(26590..26733)
                     /locus_tag="ACFOAE_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883911.1"
                     /translation="MARYRRNFIAGGTFFFTVKLADPKSRLLVEHIDFAGGLYGCAKT
                     ISL"
     gene            complement(27010..28488)
                     /locus_tag="ACFOAE_000347"
     CDS             complement(27010..28488)
                     /locus_tag="ACFOAE_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003757536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC6883912.1"
                     /translation="MKLNMTIKHIKSIDELKISLPVEKGLYAITGQNGSGKSTVITCA
                     SSAYFNMKMNEYFGKTPDDASISFELNGSTRIWEKENRKWNVKYDPTFKLSGFYEGSI
                     IFGNRFRNTSFNLLMKIDRVDFSKLKPTNDFLRENLGKILHNNKNFYDKILRLDSKDA
                     DNLIKFNGDVFFYQKGDKRVSQFHMSTGENLLLSILNSIDRRNKTRRDDITPCLLLLD
                     EIELALHPSSLKRLIEFLKKISNDYNYAVYFSTHSIELISNIAPKNIFFLERHTDNSI
                     EILNPCYPAYATRILYDHEGYDYIILVEDDLAREIIRKLLKEHSLINNKLIHILPCGG
                     FTNTIDLAQEVISSNLMGKLSKISIILDRDVKEQAEKYIKKNDIIQNIPLNYLPIESL
                     EKFLKSKLINNVDHSLFRELNDFVFHQKSLTNLIEEYKDKCNINNDNNGKKFYEIIET
                     ELEARGRTRQEIIEIILKYLSKNEEKYFSSLIEFLKKNLQNF"
     gene            complement(28550..31402)
                     /gene="uvrA"
                     /locus_tag="ACFOAE_000348"
     CDS             complement(28550..31402)
                     /gene="uvrA"
                     /locus_tag="ACFOAE_000348"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFC6883913.1"
                     /translation="MCNHHPQHSHDNDTIRIRGARTHNLKNVDLDIPRHKLVVVTGLS
                     GSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTS
                     HNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVM
                     ILAPAVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRV
                     KVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRL
                     FSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLATGAIDGWDKRNQFYFQMIQSLA
                     RHYGFDVQAAWETLPEKVKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLER
                     RYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVGGEPLHEVSAWPLTKTHR
                     FFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRIRLAS
                     QIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFV
                     VDMGPGAGEHGGNVLIADTPENVAKCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVL
                     KGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPYD
                     DIRGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFS
                     FNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLD
                     MTVEEAREFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRD
                     TGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADYIVDLGP
                     EGGDGGGKIIASGSPEEVAKVKGCYTGKYLKNLILY"
     gene            31557..32354
                     /locus_tag="ACFOAE_000349"
     CDS             31557..32354
                     /locus_tag="ACFOAE_000349"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HFC6883914.1"
                     /translation="MNRLYPHPIIAREGWPIIGGGLALSLLVSICCGWWSLPFWVFTV
                     FALQFFRDPAREIPLNPEAVLSPVDGRIVVVERARDPYRDVDALKISIFMNVFNVHSQ
                     KSPADCTVTKVVYNKGKFVNADLDKASTENERNAVLATTASGREITFVQVAGLVARRI
                     LCYTQAGAKLSRGERYGFIRFGSRVDMYLPVDAQAQVAIGDKVTGVKTVLARLPLTAP
                     QIESEPESEPASQVASVETAANPSAEQRQIEAAAAKIQAAVQDVLKD"
BASE COUNT         8111 a         7943 c         8325 g         8303 t
ORIGIN      
        1 atttcaaacc gacgcgccgg gttttcaata tgcccgcgcc cgatgcagcc ttgtccgcag
       61 gcatcggcgg cagcgtccga tttttcgggg aacgcccgtc tcgggcgtat ttaaaggttc
      121 ggcggtgcgg tgttttcctg cggcaaggct tcagacggca tcgccggcgc gtccgttaga
      181 caaggcgtgc gcttggggcg ataatggcgt tttgcttttt tgaaagcctt gcaatgtccc
      241 gaaacctgct tgtccgctgg cttgtcgtct gcctcatccc tttggcgaca cttgccgttt
      301 tcgtcgccaa tccgcccgaa gacaaacccc agcatctgat caacggcatc atccttgcct
      361 gcgaagcgac gtttttgttc aaattcgtcc ttttcgacac catcaagcat catttgaaac
      421 aagagtttga tttgaaacgt caaaccatgt tgctgtttat tccgattgtt ttgctggttg
      481 tgtatttgtt ccactatttc ggcgcgtttt agcttgtttc cgttatttct atgaatactc
      541 ctccttttgt ctgttggatt ttttgcaagg tcatcgacaa tttcggcgac atcggcgttt
      601 cgtggcggct cgcccgtgtt ttgcaccgcg aactcggttg gcaggtgcat ttgtggacgg
      661 acgatgtatc cgccttacgt gcgctttgcc ctgatttgcc cgatgttccc tgcgttcatc
      721 aggatattca tgtccgcact tggcattccg atgcggcaga tattgatacc gcgcctgttc
      781 ccgatgtcgt catcgaaact tttgcctgcg acctgcccga aaatgtgctg cacattatcc
      841 gccgacacaa gccgctttgg ctgaattggg aatatttgag cgcggaggaa agcaatgaaa
      901 ggctgcacct gatgccttcg ccgcaggaag gtgttcaaaa atatttttgg tttatgggtt
      961 tcagcgaaaa aagcggcggg ttgatacgcg aacgcgatta ctgcgaagcc gtccgtttcg
     1021 atagcgaagc cctgcgtcag cggctgatgc ttcccgaaaa aaacgccccc gaatggctgc
     1081 ttttcggcta tcggagcgat gtttgggcaa agtggctgga aatgtggcga caggcaggca
     1141 gcccgatgac actgttgctg gcggggacgc aaatcatcga cagcctcaaa caaagcggcg
     1201 ttattccgca agatgccctg caaaacgacg gcgatgtttt tcagacggca tccgtccgcc
     1261 tcgtcaaaat ccctttcgtg ccgcaacagg acttcgacaa actgctgcac ctcgccgact
     1321 gcgccgtgat acgcggcgaa gacagtttcg tgcgcgccca gcttgccggc aaacccttct
     1381 tttggcacat ctacccgcaa gacgagaatg tccatctcga caaactccac gccttttggg
     1441 ataaggcaca cggtttctac acgcccgaaa ccgtgtcggc acaccgccgt ctttcggacg
     1501 acctcaacgg cggaggggct ttatccgcca cgcaacgcct cgaatgttgg caaatcctgc
     1561 aacaacatca aaacggctgg cggcaaggcg cggaggattg gagccgttat cttttcgggc
     1621 agccttccgc atccgaaaaa ctcgccgcct ttgtttcaaa gcatcaaaaa atacgctaga
     1681 atagtgcgtt ttacgacaac cgatttgatt ggaaaatcac aatgaaaaca gcacaagaac
     1741 tgcgcgccgg caatgtattt atggtcggca acgatcctat ggtcgttcaa aaaaccgaat
     1801 acatcaaagg cggccgctct tccgccaaag tcagcatgaa actgaaaaac ctgctgaccg
     1861 gcgcggcttc cgaaaccatt tacaaagccg acgacaaatt cgacgtggtc atcctgtccc
     1921 gcaaaaactg tacgtacagc tactttgccg atccgatgta cgtctttatg gacgaagaat
     1981 tcaaccaata cgaaatcgaa gccgacaaca tcggcgacgc gttgaaattc atcgttgacg
     2041 gcatggaaga ccaatgcgaa gttaccttct acgaaggcaa ccccatctcc gtagaactgc
     2101 ccaccatcat cgtacgcgaa gtcgagtata ccgagcctgc cgtcaaaggc gatacttccg
     2161 gcaaagtgat gaaaaccgcg cgcctggtcg gcggcaccga aatccaagtg atgtcttaca
     2221 tcgaaaacgg cgacaaaatc gaaatcgata cccgcaccgg cgaattccgc aaacgcgctt
     2281 gatttgttgc attgaaaaat gccgtctgaa aacgtttcag acggcatttt tttatcttcg
     2341 ccccaagttt ggattgaagt agatgttttt ttcgtaaacg acaatacgcg tgattttgcc
     2401 attttcgtca aaatggatgt ctaaaaacgg tttgtcggga ttgcgttcac ggttggacag
     2461 ccggaagagt gattggtttt caagcatttc tccgtgtatt ttcagatagc cgggcaattg
     2521 gccgatgtat tggaaattgc cgccaagtcc gttgttgtgc cggctcgaat aggcaggggt
     2581 tgccgaaact tcaaaataac gcgtgcgttt cggctcctcg ccttgtccgc gggtttcttg
     2641 actgccctgt atcagcaaca gcgtcgcttc tcggaggcgg cgttcctgtt ccatcaaggc
     2701 atcttgtgcc tgccggctga tcgtgcgctt tccgtaacgc aagtcttcaa ttgccagtat
     2761 gattttctga tggtagtcgg gatcttcagg gcggatgtcg ggaaacagca gccgctgtat
     2821 gttgtcatag ccgccgccgg gtaagccgaa acgggtttcc agttcgtgat gggaaagggc
     2881 aaacagacag tccgagtcaa tgtgttcggc gatttgctgc atgagatcgt caatgccggt
     2941 ggcggggtgc aggtcggtgc aatttgacgg cggcacgctt tctgcctgct tgacgttatc
     3001 aggggcggat gcggccggtt gcaaatcggt ttggggcgcg gaagacgaag cggcggatgc
     3061 cgtggacgag gcggcggatg cgccgttttc tttcgtttta tcttctttgc tcggggaaca
     3121 cgcggtcagc atcattgcgg caagccataa gagaagtgat gaggttttgt ttttcattct
     3181 attgtttcca gtattaaaga ggccgtctga aaacctaccg tttcattttt cagacggcct
     3241 gttgttaata gaaccgaaga acctgttatt gccgacaagg ttctcaacct gtcttagccg
     3301 acgcggtaaa acgcaaggct gcccaaaagg ttggggaaat gtttgacctg tctgttgccc
     3361 gtcatcacgg cgcgttcgag gacgcggatg ttgtttttgg cgcacaacaa atcaaagtct
     3421 ttgagcgtgc accaatggat attgggcgtg tcgtaccaat ggtagggcat acgttcggaa
     3481 accggcatat gtccgccgag tgcgatttgg acgcggttgc gccagtagcc gaaattcggg
     3541 aagctgacaa tcgcctgttt ggcaacgcgc atcaggcagc gcaggatttt ttcggtattc
     3601 tgcatcgctt ggatggtttg gctcaacaca atcacatcaa aactttgatc gttgaatgcg
     3661 gttaaacctt cttccaaatc ggcttggata acattcacgc cgcgcgacat cgcggcaatc
     3721 acgctgtcgg tgtcgatttc gatgccgtag ccgctgcatt ttttgtgttc gaccaatgcg
     3781 gcaagcagtt cgccgtcgcc gcagcccaag tccaagacgc ggctgccttc gggtatccgg
     3841 tcgtaaatca gttgcaaatc atcgcgcagg ttcattgctg acattcctta taaacgttgt
     3901 tcatataggc ggcgaccgca cgcatatagg cttcgtcttc cattaaaaag gcatcgtgcc
     3961 cgtgtgcgga tttgacttcg atatactgca cggatttttg ggcggcaatc agggccttga
     4021 ccagttcgtg cgaacgttcg ggcgcgaaac gccaatcggt gctgaagctg gcgacaaaga
     4081 attttgcctg cacatcctgc acggcgcggg tcaggctgtt gccgaaatcc gccgccggat
     4141 cgaaatagtc caaagctttg gtcatcagca aataggtgtt ggcatcaaac cgcccgacga
     4201 atttgtcgcc ctgatagcgc agataggatt ctacttcaaa ttcaacgcca taaccgtatt
     4261 gatagccgtt ggaacgcaaa tcgcgtccga attttttgcc caaaccgtct tcggcaagat
     4321 aggtaatgtg ccccatcatg cgggcaatcc gcaagccccg tgcaggaacg gtattatggc
     4381 tgcggtaatg tccttcgttg aaatcggggt cggtcaaaat cgcctgacgc gccacatcgt
     4441 tgaacgcgat attttgcgtg gacagtttcg gcgcagacgc aatcactaag gcatggcgca
     4501 cgcgttcggg ataggaaatc gcccactgca aagcctgcat gccgcccaag ctgccgccga
     4561 caaccgccgc ccattgcccg atgccgagat aatcggcaag cgcggcttgg gattttaccc
     4621 agtccttcac cgtaaccagc ggaaaatccg cgccgtattc cctgcccgtt tcaggattaa
     4681 tcgacaaagg cccgctgctg ccgtcgcagc cgcccagatt attcaaaccg accacgaaaa
     4741 aacgttccgt atcaatcggt ttgccaggtc cgaccatatt gtcccaccag cccgtatatt
     4801 tatcttccgc cgaatgcctg cccgcaacat gatggttgcc cgacagcgcg tggcagatta
     4861 aaaccgcatt gtttttttca gcattcagct cgccgtaggt ttcaatcatc agatcgaaac
     4921 gcggcaaagt tttaccgttt tccaaaacca gcggcatctc aaacggaatt ttttggggca
     4981 ttacaatgcc caccgaggca ttttgactca tatcctgttc caacaaatgc ggcgaaaagc
     5041 gttattatat cgcaaacggc atgacttttt gacacggtcg gacaagcagc cggacgcgtt
     5101 tgaccctcat ccgccgcaca cgaatcatac tttttcagac gacctccacc gcttcccgac
     5161 atgataggca gacttttccg tatttttttc tttttcgcac ttgccgcgtt gattatcaac
     5221 cgccttttca gccgcaggca aaaacgcgcc ctgcgcgaag tcgccgaaat cagcgcatgg
     5281 gtactgctcg gtgcagccgc cgcgatgctg ttttggtatc tgtttatgct gtatttcaaa
     5341 cacattccgg attcgtattg acggaaaaaa tgccgtctga aacgcatttt tctgtttcag
     5401 acggcatatt tgatgaaaag ggcttgcggt aggaggtgct ttatagtgga ttaaatttaa
     5461 accagtacgg cgttgcctcg ccttgccgta ctatttgtac tgtctgcggc ttcgtcgcct
     5521 tgtcctgatt tttgttaatc cactatacaa ccgaagcagg aagggcaggg agtcagcgtt
     5581 ggcgcgcttt aaaacgcgga ttgcttttgc agatgacgta aactttgccc ctgcgtctga
     5641 cgatttggca gtcgcggtgg cgttgtttgg cggttttgag tgaagacaga acctgcatta
     5701 tttgtccttt ctaaacgatg acatgacgga ttggaaacgt tggttgaact tgctggcgcg
     5761 tccttcggtg ttgacgttac gctgcttgcc ggtatagacg ggatgggatg cggaagaagt
     5821 atccagcgaa aacagcggat attctttgcc gtctgtccaa accatcgttt ttccgtgtgt
     5881 ttcggcacag gagcggatta accagccttc attggcgctg ctatcgaaaa aaaggacggt
     5941 tcggtaattg tcaggatgaa tattcggttt catatatcgc cttagttgga ttgttataac
     6001 ataacaaact ttatcataaa tttagaaggc ttgtacaagg aaatttaact atttttgtaa
     6061 tatattagaa attttcatga taaacctgaa aatcttgaaa ttgactcata ttcggtgcaa
     6121 ttttattatg ttgcctgaaa tatcatataa aagataataa aaggtacgca gccatgaatt
     6181 acgcaaaaga aatcaatgcg ttaaacaaca gcctttccga tttgaaaggc gacatcaacg
     6241 tttcgtttga atttttcccg ccgaaaaacg aacaaatgga aacgatgctg tgggattcca
     6301 tccaccgtct gcaaaccctg catcccaagt tcgtatccgt aacctacggc gcaaattccg
     6361 gcgaacgcga ccgcacgcac ggcatcgtca aacgcattaa gcaagaaacc ggcttggaag
     6421 ccgcgccgca cctgaccggc atcgacgctt ctcccgacga attgcgccaa attgccaaag
     6481 attattggga cagcggcatc cgccgcattg tcgccctgcg cggcgacgag ccgcccggtt
     6541 acgagaaaaa accgttttat gccgaagact tggttaagct attacgctcc gtcgccgact
     6601 tcgacatttc tgtagcagca tatcccgaag tgcatcccga agcgaaatcc gcacaagccg
     6661 acctgattaa tttgaaacgc aaaatcgatg cgggcgcgaa ccacgtcatc acccaattct
     6721 tcttcgatgt ggaacgctac ctgcgcttcc gcgaccgctg cgtgatgttg ggcatcgatg
     6781 tggaaatcgt ccccggtatt ttgcctgtta ccaacttcaa gcagctcggt aaaatggctc
     6841 aagtaaccaa cgtcaaaatc ccaagctggc tgtcgcaaat gtatgaaggt ttggacgacg
     6901 accaaggtac gcgcaatctg gtggcggcaa gtatcgccat cgatatggtc aaagtcctgt
     6961 cccgcgaagg cgtgaaagat ttccacttct atacgcttaa ccgcagcgag ctgacttacg
     7021 ccatttgcca tattttaggc gtgcgccctt aaagccgtat caaacagttt cagacggcat
     7081 ctaaggtgtc taaaaagcaa aacaccgccc catccgagcc attctgattt acaataccgg
     7141 ccgattcgga ttgaaccggt ccttacaaaa tccaactgga gagttcaaca tgacaacatt
     7201 acatttctca ggcttcccgc gtgtcggcgc cttccgcgaa ttgaaattcg cacaagaaaa
     7261 atactggcgc aaagaaatca gcgagcaaga attgctggct gttgctaaag acttgcgcga
     7321 gaaaaactgg aaacaccagg ccgctgccaa cgctgattac gttgctgtag gcgatttcac
     7381 tttctacgac cacatcctcg acctgcaagt cgctaccggt gccatccctg cccgtttcgg
     7441 cttcgacagc caaaacctgt ctttggaaca attcttccaa ctggcacgcg gcaataaaga
     7501 ccaattcgct atcgaaatga ccaaatggtt cgacaccaac taccactact tggtgcctga
     7561 attccacgcc gataccgaat tcaaagcgaa cgccaaacac tacgttcaac agctgcaaga
     7621 agcccaagct ttgggcctga aagccaaacc gaccgttgtt ggtccgttga ccttcctgtg
     7681 ggttggtaaa gaaaaaggcg ctgtcgaatt tgaccgcttg agcctgttgc caaaattatt
     7741 gccggtttat gttgaaatcc tgaccgaatt ggccgctgcc ggtgccgaat ggattcaaat
     7801 cgatgagcca gcattggcgg ttgacctgcc gcaagcgtgg ttggatgcgt accaagacgt
     7861 ttacgccact ttgagccaag tgaatgccaa aatcttgttg agcacttatt tcggttcggt
     7921 tgccgcacac gcaggtcgtc tgaaagcctt gcctgtggcc ggtttgcaca tcgatttggt
     7981 gcgcgcgccc gagcaattgg acgcatttgc tgattacggc aaagtgttgt ctgccggtgt
     8041 gattgatggc cgtaatattt ggcgcgccaa tttaaacaac gtattagcca cgcttgagcc
     8101 gttgaaagcc aaattgggcg accgcttgtg gatttccagc tcatgctcgc tgctgcacac
     8161 gccatacgat ttgtcggtag aagaaaagct gaaagtcaac aaacctgcct tgttctcatg
     8221 gttggctttc accttgcaga aaacgcaaga attgcgcgtg ttgaaaactg cattgaacca
     8281 aggccgcgaa gccgttgccg ccgaattggc cgacagccaa gccgctgctg attcacgcgc
     8341 caacagcacc gaaatccacc gcgccgaagt ggccaaacgc ttggctgatt taccggcaga
     8401 tgccgaccaa cgcaaatcac cgtttgccga gcgcattaaa gcgcaacaag catggctgaa
     8461 cctgccgttg ctgccgacca ccaatatcgg ttcgttcccg caaaccactg aaatccgcca
     8521 agcgcgtgcc gcgttcaaaa aaggcgaatt gtctgacgct gattacgaag ccgcgatgaa
     8581 aaaagaaatc gccttggtga ttgaagagca agaaaaactc aatttggatg tgttggtaca
     8641 cggcgaagcc gagcgtaacg acatggtgga atatttcggc gaattgctgg aaggctttgc
     8701 ctttacccaa tacggctggg tacaaagcta tggctcacgc tgcgtgaaac caccggtgat
     8761 ttacggcgat gttagccgcc cgaacgcgat gactgtggct tggtcaacct acgcccaaac
     8821 cctgaccaaa cgcccgatga aaggcatgtt gaccggtccg gtaacgattc tgcaatggtc
     8881 atttgtgcgc aacgatattc cgcgcagcac cgtgtgcaaa caaatcgcct tggccttaaa
     8941 tgacgaagta ttggatttgg aaaaagccgg tattaaagtg attcaaatcg acgaaccggc
     9001 catccgcgaa ggcctgccgt tgaaacgtgc cgattgggat gcctacttgg cttgggcaag
     9061 cgaagccttc cgcctgtcgt caaccggttg cgaagacagt acccaaatcc acacccatat
     9121 gtgttactcg gaattcaacg acatcctgcc ggccatcgcc agcatggacg cggacgtgat
     9181 taccatcgaa acttcacgtt ctgacatgga attgttgacc gcattcggcg aattcaaata
     9241 cccgaacgac atcggcccgg gcgtttacga catccacagc ccgcgcgtac cgactgaagc
     9301 cgaagttgag cacctgttgc gcaaagccat cgaggttgta ccgtttgaac gtctgtgggt
     9361 taacccagac tgcggcctga aaacacgcgg ctggaaagaa actctggaac aactccaagt
     9421 gatgatgaac gtaacccgaa aactgcgtgc cgaattggcg aaataagccg agaccgtatg
     9481 aataaatacc gtctgaaagc ctttcagacg gtattttgtc ctgatttgcg gcgcaagggc
     9541 gcagttgccg gaaaatcttt tcattgcagc ttgttttttt ctaattcggc tttatatgtg
     9601 ggaaacaggc aaatcggagt tgtgtttgat agttttaaat aatttatgtt atttgaacta
     9661 taaattatac aaatcatttt gcatggggta gaatgcccag cgattcacaa ttatttctca
     9721 aaccaatcta ttaaggagct taaaatggct ttgcaagatc gtaccggtca aaaagtacct
     9781 tccgtagtat tccgcacccg cgtcggcgac acttggaaag atgtgtctac cgatgatttg
     9841 ttcaaaggca aaaaagtagt cgtattctcc ctgcccggtg catttacccc gacttgttct
     9901 tcttcacacc tgccgcgtta caacgaattg ttcggcgcgt tcaaagaaaa cggcgttgac
     9961 gcaatctact gcgtatctgt aaacgatacg ttcgtaatga acgcttgggc tgccgaagaa
    10021 gaatccgaca acatctacat gattcctgac ggcaacggcg aatttaccga aggtatgggt
    10081 atgctggtcg gtaaagaaga cttgggcttc ggtaaacgct cttggcgtta ctccatgctg
    10141 gttaacgacg gcgtggttga aaaaatgttc atcgaacctg aagaactggg cgatccgttc
    10201 aaagtatccg atgcagatac tatgctgcaa ttcgttgctc ccgattggaa ggctcaagag
    10261 tctgtggcaa ttttcactaa accaggttgc caattctgcg ctaaagccaa acaagctttg
    10321 caagacaaag gtttgtctta cgaagaaatc gtattgggca aagatgcaac cgttacttcc
    10381 gttcgcgcca ttaccggcaa gatgactgcc cctcaagtct tcatcggcgg caaatacatc
    10441 ggcggcagcg aagatttgga agcttgcttg gctaaaaact gatagctgtt tgcttaaggc
    10501 ggtttgatta aactgtctga tataccggat agagttattc gggcggttct acactgccgc
    10561 tccgaataac tctatattta taagagaatt tggatattgt tgcactcaat cgaaattttg
    10621 tttttattta tctgaatgat gtttttgatt gggaaaatat ttaaatgccg tctgaaaccg
    10681 atatgttctg tgtcggcaat gtttcagacg aaaacggaag gacaaagatt atgaaaaaaa
    10741 ttcaagcgga tgtcgtcgta atcggcggcg gtactgccgg tatgggtgcg tttcgcaatg
    10801 cccgtttaca ttcggataat gtttacctga ttgaaaacaa tgtgttcggc acaacctgcg
    10861 cgcgcgtggg ttgtatgcct tccaaactct tgattgccgc cgcagaagcg cgccaccacg
    10921 cattgcatac cgacccgttc ggcgtgcatt tggacaaaga cagcatcgtc gtcaacggtg
    10981 aagaggtcat gcagcgcgtt aaatccgagc gtgaccgttt tgtcggcttt gtcgttgccg
    11041 atgtggaaga gtggcctgcc gacaagcgca tcatgggttc ggctaaattt atcgacgagc
    11101 ataccgtcca aatcgacgag catactcaaa ttacggcaaa aagtttcgtg attgctaccg
    11161 gttcgcgtcc cgtcatcctg ccgcaatggc agtctttggg caatcgtttg attatcaacg
    11221 atgacgtttt ctcatgggat acgctgccta agcgcgttgc cgtgttcggg ccgggtgtta
    11281 tcggtttgga actgggtcag gcattgcacc gtttgggcgt gaaagttgaa attttcggtt
    11341 tgggcggaat catcggcggc atttccgacc ccgtcgtttc agacgaggcg aaagccgtgt
    11401 tcggcgaaga attgaaactg catctggatg ctaaaaccga ggtcaaactc gatgcagacg
    11461 gcaatgtaga agtccattgg gagcaggatg gcgaaaaagg cgtatttgtt gccgaatata
    11521 tgctggcagc cgtgggccgc cgtccgaacg ttgacaatat cggtttggaa aatatcaata
    11581 tcgaaaaaga tgcgcgcggc gtacctgttg ccgacccgct gaccatgcag accagtattc
    11641 cgcatatctt catcgcaggc gatgcgtcca accaactgcc tctgctgcat gaagctgccg
    11701 accaaggcaa gattgccggc gataacgcgg gccgctaccc gaatatcggc ggcggtttgc
    11761 ggcgcagcac catcggcgtg gtgtttacca gtccgcaaat cggctttgtc ggtctgaaat
    11821 acgcgcaggt tgccgcgcaa taccaagccg acgaatttgt catcggcgaa gtatcgttca
    11881 aaaaccaagg ccgcagccgc gtgatgctgg taaacaaagg ccatatgcgc ctgtatgccg
    11941 aaaaagccac cggccgcttt atcggcgcgg aaatcgtagg ccctgccgcc gaacatttgg
    12001 cgcacttgtt ggcatgggcg catcaaatga agatgaccgt tccgcaaatg ctggatatgc
    12061 cgttctacca tcccgttatc gaggaaggtc tgcgtaccgc gttgcgcgat gccgatgcga
    12121 aattgaaagc ctgaccgata tggcaaaaca atgccgtctg aaattttttc agacggcatt
    12181 ttgtttttgg ggatggggtc ggatgctgat accgtgtcgg gaagggggcg gcaaaactaa
    12241 aaatctttct tttaatctgc tgtttccacg cgtgtttgtc aaaatctatc agtttgtttt
    12301 taaaatacac tgttcaaaat gggataaaac aggtaaatta acgtttatgt aacccagtgt
    12361 agcaatgggt ttacggtttt tgagtcgata tataactaca gaggaattga ctatgtctgc
    12421 caaaccgcgt cctgtttatc tggatttgcc gaacatccgt ctgccgatac ccgggatagt
    12481 ttccatcctt caccgcatca gtggggtcgg gctgtttatt atgctgcctt tcctgctgta
    12541 tttcctgtcc ggtaccctga gtcaagagtc tgcatttgaa acttaccgtg ccattgtttc
    12601 ccatcctttg gtcaagctgg ttttaatcgg tgtattgtgg gcttatctgc accattctct
    12661 cgccggtatc cgctttttat ttttggatgc gcacaaaggc cttgagctga atactgcgcg
    12721 caataccgct aaagccgtat ttgcttctgc attggttttg actgtcgttt tgggagcgtt
    12781 gttatggtag aacgtaaatt gaccggtgcc cattacggtt tgcgcgattg ggcgatgcaa
    12841 cgtgcgactg cggttattat gttgatttat accgttgcac ttttagtggt tctattttcc
    12901 ctgcctaaag aatattcggc atggcaggca ttttttagtc aaacttgggt aaaagtattt
    12961 acccaagtga gcttcatcgc cgtattcttg cacgcttggg tgggtatccg tgatttgtgg
    13021 atggactata tcaaaccctt cggcgtgcgt ttgtttttgc aggttgccac catcgtctgg
    13081 ctggtcggct gcttggtgta ttcaattaaa gtaatttggg ggtaagtatg ggttttcctg
    13141 ttcgcaagtt tgatgccgtg attgtcggcg gtggtggtgc aggtttacgc gcagccctcc
    13201 aattatccaa atccggtctg aattgtgccg ttttgtctaa agtgttcccg acccgttcgc
    13261 ataccgtagc ggcgcagggc ggtatttccg cctctctggg taatgtgcag gaagaccgtt
    13321 gggactggca catgtacgat accgtgaaag gttccgactg gttgggcgac caagatgcga
    13381 ttgagtttat gtgccgcgcc gcgcctgaag ccgtaattga gttggaacac atgggtatgc
    13441 cttttgaccg tgtggaaagc ggtaaaattt atcagcgtcc tttcggcggc catactgccg
    13501 aacacggtaa acgcgcggta gaacgcgcct gtgcggttgc cgaccgtaca ggtcatgcga
    13561 tgctgcatac tttgtaccaa caaaacgtcc gtgccaatac gcaattcttt gtggaatgga
    13621 cggcacaaga tttgattcgt gatgaaaacg gcgatgtcgt cggcgtaacc gccatggaaa
    13681 tggaaaccgg cgaagtttat attttccacg ctaaagctgt gatgtttgct accggcggcg
    13741 gcggccgtat ttatgcgtct tctaccaatg cctatatgaa taccggcgat ggtttgggta
    13801 tttgtgcgcg tgcaggtatc ccgttggaag acatggaatt ctggcaattc cacccgaccg
    13861 gcgtggcagg tgcgggcgtg ttgattaccg aaggcgtacg cggcgagggc ggtattctgt
    13921 tgaatgccga cggcgaacgc tttatggaac gctatgcgcc gaccgtaaaa gacttggctt
    13981 ctcgcgacgt tgtttcccgc gcgatggcga tggaaatcta cgaaggtcgc ggttgcggta
    14041 aaaacaaaga ccatgtctta ctgaaaatcg accatatcgg cgcagaaaaa attatggaaa
    14101 aactgccggg catccgcgag atttccattc agttcgctgg tatcgatccg attaaagacc
    14161 cgattcccgt tgtgccgact acccactata tgatgggcgg cattccgacc aattaccacg
    14221 gcgaagtcgt tgtgccgcaa ggagacgaat acgaagtgcc tgtaaaaggc ctgtatgccg
    14281 caggtgagtg cgcctgtgct tccgtacacg gtgcgaaccg tttgggtacg aactccctgc
    14341 tggacttggt ggtattcggt aaagctgccg gcgacagcat gattaaattc atcaaagagc
    14401 aaagcgactg gaaacctctg cctgcggatg cgggcgagct gacccgccaa cgtatcgagc
    14461 gtttggacaa tcaaactgat ggcgaaaacg ttgatgcatt gcgtcgcgaa ttgcaacgct
    14521 ccgtacaact gcacgccggc gtgttccgta ctgatgagat tctgagcaaa ggcgttcgag
    14581 aagtcatggc gattgccgag cgtgtgaaac gtaccgaaat caaagacaag agcaaagtgt
    14641 ggaataccgc gcgtatcgag gctttggaat tggataacct aattgaagtg gcgaaagcga
    14701 ctttggtgtc tgccgaagca cgtaaagaat cacgcggtgc gcacgcttca gacgaccatc
    14761 ctgagcgcga tgatgaaaac tggatgaaac atacgctata ccattcagat accaatacct
    14821 tgtcctacaa accggtgcac accaagcctt tgagcgtgga atacatcaaa ccggccaagc
    14881 gcgtttattg atgcgttttc agacggtctt cgcctcaaag gtcgtctgaa atctaaccat
    14941 acccacattg aactgcttga atttataata caaaatcatt gggcagttga tgagaaaagg
    15001 aacacttctc atggaaaaaa tgagttttga aatttaccgt tacaacccgg atgttgatgc
    15061 caagccttat atgcagcgtt acgagttgga attggaaccg accgacgtga aacttttgga
    15121 cgctttagtg cgcctgaaag cacaagacga taccttgtct ttccgccgct cctgccgcga
    15181 agggatttgc ggttctgacg gtatgaacat caacggcaaa aacggcttgg cgtgtttgac
    15241 cgatctgcgt ggcttgaaac agccggttaa aattcgtcct ctgccaggtc tgcctgttat
    15301 ccgcgacctg attgtggata tgacccagtt cttcaaacaa taccattccg tcaaacctta
    15361 tgttgtcaac gataatccga ttgatgcgga caaagagcgt ctgcaaactc aggaagagcg
    15421 taaagagttg gacggtttgt acgagtgtat tttgtgcgcc tgctgttcga ctgcctgccc
    15481 gtcattttgg tggaaccctg ataaattcgt tggtccgtcc ggtttgctga atgcttaccg
    15541 tttcattgcg gacagccgtg ataccatcac taatgagcgt ttggataatc tgaacgaccc
    15601 ataccgtttg ttccgttgcc acaccattat gaactgcgta gacgtatgtc ctaaacactt
    15661 gaatccgacc cgagccatcg gtaagattaa agagattatg ttgaaacggg ccgtttaaga
    15721 aatgatggtt tttgacgata ttgccaaacg gaaaatccgt tttcaaaccc gccggggatt
    15781 gttggaatta gatttaatct tcggcaggtt tatggaaaaa gaattcgagc atttgagcga
    15841 taaagagctg tccgagtttt ccgaaatcct tgaatttcaa gatcaagaat tgcttgcctt
    15901 gattaacggg cattcggaaa cggacaaagg gcaccttatc ccgatgcttg aaaaaatcag
    15961 acgggcatga ggcatctgaa atctgcctgc aggcagattt caaaatgcaa aagccgtctg
    16021 aaggcaaaga acgtgctgcg gatgcagtaa cgtgggttat aacttgcaaa ggagcaataa
    16081 tatgtccaaa tcaatcaaac tcaacgtacc gggtcaggca ggtttggagc tgccggtatt
    16141 ggaagccagc atcgggcacg atgtggttga cattcggggg ctgacaaaaa atacaggttt
    16201 gttttccttc gaccccggat ttgtttcaac cgcaagctgt gagtctaaaa ttacttacat
    16261 cgacggcgat caaggcttgc tttattatcg cggatacccc atcgagcagc tggccgaaaa
    16321 gtccgattat ttggaagtct gctacctgtt gatttacggc gaactgccaa ctcccgagca
    16381 aaaggcagaa tttgacaata ctgtccgccg ccacacgatg gtgcatgaac agctgacttg
    16441 gttcttccgg gggttccgcc gcgacgcgca tccgatggcg atgatggtcg gcgtggtcgg
    16501 tgcgctgtct gcgttctacc aagacagctt ggacattagc aatcccgaac accgcaaaat
    16561 cgcgatttac cgcctgattt ccaaaatccc gaccattgcg gcaatgtgct accgctattc
    16621 aaacggtctg ccgttcaatt atccgaagaa taatctttct tattccgaaa acttccttca
    16681 tatgatgttc gccacgccgt gtgaagacta caaacccaat cccgttttgg cacgcgcgct
    16741 cgaccgcatc tttattttgc atgccgacca cgagcaaaac gcctcaactt caaccgtccg
    16801 tctggcaggg tcttcgggtg cgaatccgtt tgcctgtatt gctgccggta tcgcctgcct
    16861 gtggggtgct tcgcacggcg gtgcgaacga agccgtgttg aaaatgttgg acgaaatcgg
    16921 cgatgtgtct aatgttgccg catacatgga aggtgtgaaa caacgcaaat accgtctgat
    16981 gggcttcggt caccgcgtgt accgcaatat ggatccgcgt gccagcatta tgcgcgaaac
    17041 ctgctatgaa gttttgaagg aattgggctt ggaagacagt ccgaaattca aactggcgat
    17101 ggaattggaa cagattgcgc tgaaagaccc gttctttatc gaacgcaagc tgtatccaaa
    17161 cgtcgatttc tattccggca tcgtcctgtc cgctctgggc atcccgaccg aaatgtttac
    17221 cgtcatcttc gccctgtcgc gcagcgtagg ttggatttcg cactggcacg agatgatcag
    17281 cgatccttcg ctgaaaatcg gccgcccgcg ccagctttat accggttcgg aacgccgcga
    17341 ttatgtgccg gcaggagaga ggtaacatac attaatatat tgtcaaacag gcaatattag
    17401 agaatcggat tgctttctgt atacatttga ttgtagtcgg atgaaatcaa tacaggcaat
    17461 ccggtttaaa atagggtaga ataaaatgtc ttttcagacg gcatcagttc agccgtcagg
    17521 acgcggactt ctaccctttg tttatatttt aaagaaaaga gcgcacgcca tgatggacga
    17581 aaaactcaat ttctcttacc tgttcggttc gaacgcaccc tacattgagg aattgtacga
    17641 ggcttttttg gaaaaccccg atgcggttga tgaaaaatgg aagcagtatt tcaccgattt
    17701 gagcaaacag ccggggacgg ttgctgtcga tgtcgcacac acaccgattc gcgaatcatt
    17761 tgttactttg gcgaaaaaga aaattgcatc tgccgttgcg ggcggtgcgg atgaggcaat
    17821 gctgaaaaag caagtcagcg ttttacggct gatttctgcc tatcgtatcc aaggcgtggg
    17881 tgcagcccaa cttgatccgc tcaaacgtat ccccccgcgc gatattgaag ccctcgatcc
    17941 gaaattccac ggtctgtctg atgccgatat ggcgcttcaa ttcaatatgg gcgagggcga
    18001 ttttgccaat cgcggcaaac tgcctttgtc ccaaatcatc agcaacctca aacaaaccta
    18061 ctgcggccac atcgcattgg aatatatcta tattcccaat accgaagagc gccgctgggt
    18121 acgcaattat tttgaaagcg tattgtccac accgcattac aatgccgatc aaaaacgccg
    18181 tatcttgaaa gagatgactg ctgccgagac tttggaacgt tatctgcata ccaaatatgt
    18241 cggtcagaaa cgtttcggtg tcgaaggcgg cgaaagcgcg attgccggtt tgaactacct
    18301 gattcaaaac gccggtaaag acggcgtgga agaagtcatc atcggtatgg cgcaccgtgg
    18361 ccgtctgaat gttttggtga acattttggg taaaaaaccc ggagatttgt tcgctgagtt
    18421 tgaaggccgt gccgaaatca aattgcctag cggcgacgtg aaataccaca tgggcttcag
    18481 ctccgacatc gccactccac atggtccgat gcacgtttct ttggcgttca acccgtcaca
    18541 cttggaaatc gtcaatccgg tagtggaagg ttctgcacgc gccaagcaaa aacgtttggg
    18601 cgaaaacggc cgcgataaag tcttgcccgt attgattcac ggcgactccg catttatcgg
    18661 tttgggtgtc aaccaagcga cattcaacct gtctaaaacg cgcggttata ccaccggcgg
    18721 tacggttcat atcgtcatca acaatcaaat cggctttacc acttccgata tccgcgatac
    18781 ccgttcaacc gtacactgta ccgatatcgc aaaaatggtt tccgctccgg ttatccatgt
    18841 gaacggcgat gatcctgagc gtgtttgctt tgccatccaa gccgctttgg attaccgcaa
    18901 aaaattccat aaagacatcg tgattgacgt tgtctgctac cgtaaatggg gtcacaacga
    18961 gggcgatgat ccgaccttga cccaaccgat gatgtacaaa aaagtatcgc aacaccccgg
    19021 tgcgcgtgct ttgtacaccg agcaactgat tgccgaaggc gtggtaaccc aagccgaggc
    19081 agacggttac atccaagcct accgtgatgc tttggacaaa ggcgaacacg tcgagcaaac
    19141 aacgttgagc aactttcaac gcacgcaaat cgactggagc aaataccaag gcaaagattg
    19201 gcgcgaacac atcgaaaccg gtttgcctgc cgcggatatt gagcgtctta ccgagaaatt
    19261 taccgccgta ccagaaggct ttgccctgca tccgactgca aaacgtgtga ttgaagcgcg
    19321 taaagccatg gcatccggca aacaagccat cgactggggt atggccgaaa ccttggcata
    19381 cgcaagcctt gtaaccaaag gtcatggcgt gcgtatctcc ggtgaggact ccggtcgcgg
    19441 tacgttctcg caccgccatg ccgtattgca cgatcaaaac cgtgaaaaat gggacgacgg
    19501 tacttatgtt cctctgcgcc atatgggcga aggcatgggc gagttcctgg ttatcgactc
    19561 catcttgaac gaagaggccg tgatggcgtt cgagtacggc tttgcctgct ccgctcctga
    19621 caagctcacc atttgggaag ctcaattcgg tgacttcgcc aacggcgcgc aagtgacgat
    19681 tgaccaattc ctgtcttcag gcgaaaccaa atggggtcgc ttgtgcggtc tgaccaccat
    19741 cctgccgcac ggttacgacg gtcaaggccc tgagcactct tctgcacgcg tagaacgttg
    19801 gttgcaactg tgttctgaga acaatatgca agtcatcatg ccatctgaag cgtcgcaaat
    19861 gttccacctc ttgcaacgtc aagtcttagg ttcataccgc aaaccgctgg tgattttcat
    19921 gtccaaacgc ctgttgcgat tcaaaggtgc aatgagcccg ctggaaaact tcaccgaagg
    19981 ttcgactttc cgtccggtta tcggcgatac cgccgaacgc gcaagcaacg acagcgtgaa
    20041 acgcgtggta ttgtgtgccg gtcaggttta ctatgacttg gaagccggtc gagccgaacg
    20101 taaactggaa gatgatgttg cgattgtccg cgttgagcag ctgtatccgt tcccatacga
    20161 tgaggttaaa gccgaactgg cgaaatatcc gaacgcaaaa tctgtggttt gggcgcaaga
    20221 agagccgaaa aaccaaggcg cgttctacca aatccgccac cgcatcgaag acgttatcag
    20281 cgaagagcaa aaactgtctt atgccggtcg tccaagcagc gcatcgcctg cagtgggcta
    20341 ctcaagcaaa cacattgctc aattgaaaca attggttgaa gacgctttgg cattgtaagc
    20401 caagtagcat tccgtctgag gctgctcagg cggaacaccc atatgcagaa ttaaaaacac
    20461 acaacaggcc gtctgaaagg gccattggag acacaaaatg attattgatg taaaagtacc
    20521 tatgctgtct gaaagcgtat ctgaaggcac gctcttggaa tggaagaaaa aagttggcga
    20581 agccattgcc cgtgacgaaa tcctgatcga tatcgaaacg gacaaagtgg ttttggaagt
    20641 accttctcca caagccggcg tattggttga aatcgtagcg caagacggtg aaaccgttgt
    20701 tgccgatcaa gttttggcac gcatcgatac agctgctact gccgccgctg aagctccagc
    20761 cgctgctcct gccgaagcag ccccagccgc cgctcctgct gctgcacaaa acaacgctgc
    20821 tatgcctgcc gccgccaaac tggctgccga aaccggtgtt gacgtgaacg cattgcaagg
    20881 ttccggccgt gacggtcgcg tattgaaaga agatgtacaa aatgccgctg ccaaacctgc
    20941 cgcagccgct gctcctgctg ttacacttcc tgccggcgca cgtcccgaag aacgcgtacc
    21001 gatgagccgc ctgcgtgccc gtgttgcaga acgtctcttg gcttctcaac aagaaaacgc
    21061 cattctgact acattcaacg aagtcaacat gaagccaatc atggacttgc gtgcgaagta
    21121 caaagaaaaa ttcgagaaag aacacggcgt aaaactgggc tttatgtcct tcttcgttaa
    21181 agccgcggtt gccgccctga aaaaatatcc ggttgtgaat gcttctgttg acggcaaaga
    21241 catcgtgtat cacggctact tcgatatcgg tatcgccatc ggcagcccac gcggtttggt
    21301 tgtaccaatc ctgcgcgatg ccgaccaaat gagcattgcc gacatcgaac aagcaattgt
    21361 tgattacgcg aaaaaagcca aagacggcaa aatcgctatc gaagatctga ccggcggtac
    21421 attcagtatt accaacggcg gtactttcgg ttctatgatg tccaccccga tcatcaatcc
    21481 gcctcaatct gcgattttgg gtatgcacgc cactaaagag cgcgctgtgg ttgaaaacgg
    21541 ccaagttgtt gtccgtccaa tgatgtatct ggctctgtct tacgaccacc gtatcattga
    21601 cggccgcgaa gctgtattga ccttggtagc cattaaagac gcgttggaag acccagcccg
    21661 cctgttgttg gatctgtaat cgtttcagac ggccttttat ttgttaatga aaaggccgtc
    21721 tgaattttta tagtggatta aatttaaacc agtacggcgt tgcctcgcct tgccgtacta
    21781 tctgtactgc ctgcggcttc gtcgccttgt cctgatttaa atttaatcca ctatatttag
    21841 atgtagcgta atgtagtatc gtgctacaat aggctcaacg aacgattgag gtcgtctgaa
    21901 acatttgatt cgaatgaatc ggcagatatg gactttcaga cggctttttc ttaaaaccat
    21961 caaaacgcag tcattcaaaa taaaaaagaa acgaaaagta tcgtttttat tttgagatac
    22021 tgctaaaagc aaaggatgac acgatgtctc aatatgatgt agtagtgatt ggtgcaggcc
    22081 cgggcggata cgttgccgcc atccgtgccg cacaactggg tttcaaaact gcctgtgtcg
    22141 atgcaggcgt taacaaagca ggcaatgccc ctgcattggg cggtacttgc ttgaacgtag
    22201 gttgtatccc ttctaaagcc ctgttgcaat ccagcgaaca tttccacgct gcgcaacacg
    22261 attttgccga acacggtatc actgtcggtg acgtaaaatt cgacgcggcc aaaatgattg
    22321 agcgcaaaga tgccatcgtg accaaactga ccggcggcgt gaaattcctg ttccaaaaaa
    22381 ataaagtaac cagtctgttc ggtacggctt cctttgccgg taaaaatggc gatgcttacc
    22441 aaatcgaagt cgataacaaa ggagagaaaa ccgttatcga agccaaacac gtcatcgtag
    22501 cgaccggttc cgtaccgcgt ccgctgccac aagtcgctat cgacaatgtg aacgtattgg
    22561 acaacgaagg cgcattgaac ctgaccgaag tacctgccaa actcggcgtg atcggttccg
    22621 gcgtgatcgg tttggaaatg ggttccgtat ggaaccgcgt gggtgcagaa gttaccattc
    22681 ttgaagccgc gccgaccttc ctggctgccg cagaccaaca aatcgctaaa gaagccttca
    22741 aatacttcac caaagagcaa ggtttgagca tcgaattggg cgtgaaaatc ggcgacatca
    22801 aatctgaagg caaaggcgtt tccgttgctt acgaaactgc tgccggcgaa gccaaaaccg
    22861 aagtattcga caaactgatc gttgccatcg gccgtattcc aaacaccaaa ggcctgaacg
    22921 ctgaagccgt cggcttggaa aaagatgagc gcggctttat caaagtagat ggcgaatgcc
    22981 gtaccaacct gcctaatgta tgggcaatcg gcgacgtggt tcgcggcccg atgttggcac
    23041 acaaagccag tgacgaaggc gttgccgttg cagagcgcat tgccggtcaa aaaccgcata
    23101 tcgacttcaa caacgtacca ttcgtgattt acaccgatcc tgaaatcgct tgggtgggta
    23161 aaaccgaaga gcagctcaaa gccgaaggcg tggagtacaa aaaaggtact tcaggtttcg
    23221 gtgcaaacgg tcgcgcattg gcaatgggca aagccaaagg tacggttaaa gtgttggcag
    23281 atgccaaaac cgaccgtatc ttgggcgtac acatgattgg tccggttgtc agcgaattgg
    23341 ttatcgaagg cgtgactgcg ctcgaattct tcgccagcag cgaagacatc gcccgcatta
    23401 tccatgccca cccaaccttg tccgaagtgg ttcacgaagc tgcattggcg gccgacaaac
    23461 gcgctttgca cggttgatag acattaaagt cgtctgaaat ttttcagacg accttaatgc
    23521 cttcgacaaa ttgaatgttc cgagagctcc gttttctgat ttataattcc gtcagacaaa
    23581 caaacagcat ttacattcgt tatgaacaaa gaaatagtcg gtattttctt tataccgatg
    23641 ggcatcatca gcatgtgtat ggccgcattg tggcagatgt atgtgatgat gaccgaaact
    23701 tatacgctca accgtttcaa agataaagaa ttggtttggc gcgtggcatt gttgtttatc
    23761 agtttcagcc ttgccgttta tctgctctgt ccgaattcgc gtaaaaaagg catcgtcttt
    23821 tttattctcg ggggaggcgg tgcagccatg tatctgctgg cgcggatgtg gttgcctttc
    23881 agcaagtgaa acgacgattt tccgaccgcc gaaaggtagt ctgaaacgca cgggcttgcc
    23941 attttgaggc aaactcgggg cattccacta atctaaagga gaaatccatg aatttacacg
    24001 agtatcaggc taaagaactg ctggctagct acggtttgcc cgtacaaggc ggtattttgg
    24061 cgcacaacgg cgaagaagcc gctgcagctt acgacaaact gggcggtaag tttgccgtcg
    24121 tcaaagcaca agtacacgcc ggcggccgcg gtaaagcggg cggcgtaaaa gtcgttaaaa
    24181 gccgcgaaga agctaaagaa gtggctgaaa gcctgattgg caccaacttg gtaacttacc
    24241 aaaccgatgc caacggtcaa cctgtcaaca gcgttttggt ttgcgaagat atgtatccgg
    24301 ttcaaaccga gctgtacttg ggcgcagtgg ttgaccgttc tacccgccgc gttacattca
    24361 tggcttctac cgaaggcggt gtggaaatcg aaaaagttgc tgccgaaact ccagaaaaaa
    24421 tcttcaaagt aaccgttgat ccgctggtcg gcctgcaacc ttgccaagct cgcgaagttg
    24481 ccttccaact gggcttgaaa gacaaacaaa tcaacgagtt cgtcaaactg atgaccggcg
    24541 cgtacaaagc gtttgtcgaa aacgacttcg ccctgtttga agtcaacccg ctggcagttc
    24601 gcgaaaacgg cgcactggct tgcgtggacg gcaaaatcgg catcgacagc aacgcgctct
    24661 accgcctgcc gaaaatcgcc gaattgcgcg acaaatctca agaaaacgaa cgcgagctga
    24721 aagcttccga attcgacctg aactatgttg ccctggaagg taatatcggc tgtatggtta
    24781 atggtgccgg tttggcgatg gccaccatgg acatcatcaa actgaaaggc ggccaacctg
    24841 ccaacttctt ggacgttggc ggcggcgcaa ccaaagaccg cgtggttgaa gcgttcaaac
    24901 tgattctgga agacaaatcc gttcaaggcg tattgatcaa catcttcggc ggtatcgtac
    24961 gttgcgacat gattgcggaa gctatcgtgg cagccgttaa agaaatcaac gtcgacgttc
    25021 ctgtcgttgt ccgtctagaa ggcaacaacg ccgtactcgg cgcgaaaatc ctgaacgaat
    25081 caggcctgaa actgacttct gcagacggcc tgaatgacgc agccgaaaaa attgttgcag
    25141 ccgtaaacgc ctaaggagaa aagaatgagc gtattgatta ataaagacac caaagtattg
    25201 gttcaaggtt tcaccggtaa aaacggtact ttccactccg aacaagctct ggcttacggc
    25261 actaaagttg tcggcggcgt taccccgggc aaaggcggtc aaacccacct gaacctgcct
    25321 gtattcaaca ccatgaaaga agcggttaaa gaaaccggcg cggatgcatc tgtaatttac
    25381 gttcccgctc cgtttgtttt ggattctatc gttgaagccg ttgattcagg cgtaggcttg
    25441 gttgttgtga ttaccgaagg cgtgccaact ctggacatgc ttaaagccaa acgttacttg
    25501 gaaaccaacg gcaacggtac tcgcttggtt ggccctaact gcccgggcgt gattactccg
    25561 ggtgagtgca aaatcggtat tatgccgggc cacatccaca ctccgggccg catcggtatt
    25621 atttcccgtt ccggtacatt gacttacgaa gccgtggcac aaaccaccaa actgggcttg
    25681 ggtcaatcaa cctgtatcgg tatcggcggc gacccgattc ctggtatgaa ccaaatcgac
    25741 gcactgaaac tcttccaaga agacccagat accgacgcca tcatcatgat tggtgaaatc
    25801 ggcggtactg cggaagaaga agcagccgaa tacatccaat ccaacgtaac caaacctgtt
    25861 gtaggttaca ttgctggtgt taccgctcct aaaggcaaac gtatgggcca cgccggtgcg
    25921 attatttccg gcggcaaagg tactgccgag gaaaaattcg ccgctttcga aaaagccggt
    25981 atcgcttaca cccgcagccc tgccgagttg ggcacgacga tgctggaagt gttgaaggca
    26041 aaaggtttgg cataatcagg tttgacaact gattaaacat caaatgccgt ctgaaaccgg
    26101 aaatcgggtt tcagacggca ttttgtttgt catttcaaaa agaggcagcc tcaacatacc
    26161 cacattattt tttgcccttt gaggcagtca gaatatttat cggtcaaaca ggagcaaacc
    26221 cgtaagtcag gttgcacata tttttttgaa gtcagggaat gataagtatc gcatttgaaa
    26281 agactgatat tatttttgca ggattctgtt ttagcacgcg acattctttg tttgatagga
    26341 ttagaatgga tatagtccgc gtaacactgc aaatccgttt catcgcgcac ggtgtgttcg
    26401 taaaaacgcc gttgccaaat accgcgttcg ttccgccgct gtttgccggc ggataagttt
    26461 ttagtataag gggaatatgc ggagaatttg gttttaatca gccgccggag tagggaataa
    26521 tccgcatcgt cgggcggcag cgtccaaatg gcgtggatat ggttcggcag cacgcatacg
    26581 gcgacggttt caaagggata ttgtttttgc acatccatat aagccgcccg cgaagtcgat
    26641 atgttcgaca agcaggcgcg atttcgggtc ggcgagtttg acggtgaaaa agaatgtgcc
    26701 gccggcaatg aagtttctgc gataacgcgc cataggattt ttgtttgtgg tttgggtgtt
    26761 ggagaaggaa tgggttgttg tttaaggttt tggctttgtt gaagctgatg ttttcagacg
    26821 gcattggagg tcgtctgaaa gtgctagctt caacgaagtt aaaagttgaa acggcaaacg
    26881 gtcaatcaat caaccgcgtg tgcgtaccgc atatacccta catgttgggt tttaagttcc
    26941 gagtaattca caggtagggc gtgtggtgca gccacgcacg cggtgggata agcatgaaga
    27001 ataggcttac tagaagtttt ggagattttt cttcaaaaat tcaattaatg atgaaaaata
    27061 tttctcttca tttttactaa gatatttcaa tattatttca ataatttctt gtctagttct
    27121 acctcttgct tctagttcag tttctattat ttcatagaat tttttaccat tgttgtcatt
    27181 gttaatattg catttatctt tatattcttc tattaaattc gtcaagcttt tttgatgaaa
    27241 aacaaaatca tttagctctc taaataaaga atgatcaaca ttgttaatta attttgattt
    27301 gagaaacttt tctaaactct caattggtaa ataattcaaa ggtatatttt gaattatatc
    27361 atttttctta atatatttct ctgcttgttc tttaacatcc ctatctaaaa taatcgaaat
    27421 ttttgataac ttccccatta gattgcttga aattacttct tgtgccaagt caatggtatt
    27481 tgtaaatccc ccacaaggca aaatgtgtat caatttattg ttaattaaag agtgttcttt
    27541 taataatttt cttatgattt ctctagctaa atcatcctct actaatatta tatagtcata
    27601 accttcgtga tcatatagaa tcctggtagc atatgctgga tagcatggat tcagtatttc
    27661 tatactgtta tcagtgtgcc tttctaagaa aaatatattt ttaggtgcga tattgcttat
    27721 taattcgata gagtgtgtag aaaaatatac agcataatta taatcatttg atatcttttt
    27781 aagaaattca attaaccttt ttagtgatga tgggtgtaga gctaattcaa tttcatctaa
    27841 taacaataag catggagtta tgtcatctcg acgagtttta tttcttctgt caatagagtt
    27901 taaaatactt aacaggagat tttcccctgt tgacatatga aattgactaa cccgcttgtc
    27961 acctttttgg tagaaaaaaa catcaccatt aaatttgatt aaattatcag catctttgct
    28021 atctagtctt aaaattttgt cataaaaatt tttattgtta tgtaatattt ttcctaagtt
    28081 ttctcttaaa aaatcattcg tgggtttaag tttactaaaa tcaactctat caattttcat
    28141 aagtaagtta aagctagtgt ttctgaatct atttccaaaa attatgcttc cttcgtagaa
    28201 ccctgatagt ttgaacgtag gatcatattt gacattccat tttctatttt ccttctccca
    28261 aattcgagtt gagccattca attcaaaact aattgaagca tcatcaggtg ttttaccaaa
    28321 atactcattc attttcatat tgaagtaagc agaagaagca catgttatca ctgtactttt
    28381 accagaacca ttttgtcctg taattgcata taaccctttt tcaacaggta gactaatttt
    28441 caattcatca atggatttaa tgtgcttaat tgtcatgttt agtttcatag ttttactttc
    28501 tgagactgtt cagtgtttta aatataattt aaattaggtt tatctacttt taataaagta
    28561 ttagattttt taaatacttc ccagtataac accccttaac cttcgccact tcctctgggc
    28621 tacctgaagc aataatttta ccacctccat ctcccccttc cggccccaaa tccacaatat
    28681 aatcagccgt ttttataacg tcaagattat gctcgataat cactatcgag ttgcctttgc
    28741 ctttcagacg acctatgact tctagcagca gggcgatgtc ggcgaagtgc aggccggtgg
    28801 tgggttcgtc gaggatgtag agcgttctgc cggtgtcgcg tttggagagt tccaaggcga
    28861 gtttgacgcg ctgggcttcg ccgccggaga gggtggtggc ggattggccg agacggatgt
    28921 agcctaagcc tacgtccatc aaggtttgca gtttgcgcga tacggtgggg acggcgtcga
    28981 aaaattcacg ggcttcttcg acggtcatgt cgaggacttg gctgatgttt ttgcctttgt
    29041 attggatttc gagcgtttcg cggttgtagc gtttgccgtg gcagacttcg caggggacgt
    29101 acacgtcggg caggaagtgc atttcgactt tgatgacgcc gtcgccttgg caggcttcgc
    29161 agcggccgcc tttgacgttg aaggagaatc tgccgacgtt gtagccgcgt tcgcgcgaga
    29221 ggggtacacc ggcgaagagt tcgcggatgg gggtgaacag gccggtgtag gtggcggggt
    29281 tggagcgcgg ggtgcggccg atgggggatt ggtcgacgtt gatgactttg tcgaggtgtt
    29341 cgaggccgcg gatgtcgtcg tatggggcgg gttcttcttg ggcgcggttg agttcgcggg
    29401 cggtgatttt ggcgagggtg tcgttaatca gggtggattt gccgctgccg gatacgccgg
    29461 tgatgcaggt aatcaaaccg agcggcagct caagggtaac gtttttgagg ttgttgccgc
    29521 gcgcgccttt gaggacgagc attcggtcgg gattgactgg cgtgcgttca gacggcacgg
    29581 caatggattt tttgccgctg aggtattgtc cggtaacgga gttttcgcat ttggcgacgt
    29641 tttcgggcgt gtcggcaatc aatacgttgc cgccgtgttc gcctgcgccc gggcccatat
    29701 cgacgacgaa atcggcttcg cggatggcgt cttcgtcgtg ttcgaccacg atgacgctgt
    29761 tgcccaaatc gcgcaggcgt ttgagggtgg caagcaggcg gtcgttgtcg cgctggtgca
    29821 ggccgatgga gggttcgtcc aaaacgtaca tcacgccggt caggccgctg ccgatttggc
    29881 tggcgaggcg gatgcgctgg gcttcgccgc cggaaagggt ttcggcggaa cgggagagat
    29941 tcaggtaatc cagcccgaca ttaatcaaaa agccgagacg ttcggtgatt tctttgagga
    30001 ttttttcggc gatttgtttt ttgttgccgt ccaaatccag cgtttcaaag aatcggtggg
    30061 ttttggtcag cggccaggcg gaaacttcgt gcaacggctc gccgccgacg taaacgtagc
    30121 gggcttcttt gcgcaaacgt gcgccgccgc agctcgggca agcgcggtgg ttttggtatt
    30181 cgcgcaattt ttcgcgcacg gtttcgctgt cggtttcgcg gtagcggcgt tcgagattgg
    30241 gaatgatgcc ttcgaaggcg tggctgcggt tgaaggtggt gccgcgttcg gataggtagg
    30301 tgaaatcaat gacttccttg cccgagccgt gcagcacgac ttttttgact ttttcaggca
    30361 gcgtttccca agcagcctgc acatcgaaac cgtaatgccg cgccagcgac tgaatcattt
    30421 ggaaatagaa ctggttgcgc ttatcccagc cgtcaatcgc gcccgttgcc agcgacaatt
    30481 cgggatgcgc gaccactttt tcgggatcga agaagttggt gttgcccaag ccgtcgcaag
    30541 tcgggcagga gcccatcggg ttgttgaacg aaaacaggcg cggctctaat tcgggcaggc
    30601 tgtatgaaca tacgggacag gcgaaacgcg cggaaaacca atgctcttcg ccgctgtcca
    30661 tctccatcgc cagcgcgcgc tcgttgccgt ggcgcagcgc ggtttcaaaa ctttccgcca
    30721 gccgctgctt gatgtctgcc ttcactttca cgcggtcgat gaccacgtcg atattgtgct
    30781 tgatgttttt ttccagcttc ggcacttcgt caagttgata gacttcgccg tccacgcgca
    30841 cccgtgcaaa cccctgtgct tgcaagtcgg caaagaaatc gacaaactcg cccttacgct
    30901 ctcgcaccgc cggcgccaga atcatcacgc gcgtgtcttc cggcagcttc aacacggcat
    30961 cgaccatctg cgacacggtt tggctggata acggcagctt gtgttcgggg caatacggtg
    31021 tgccgacgcg tgcgtacaaa aggcgcaggt aatcgtggat ttccgtaacc gtaccgacgg
    31081 tggaacgcgg attgtggctg gtggatttct gctcgatgga aattgcgggc gacagacctt
    31141 cgatcaaatc gacatcgggt ttgtccatca tctgcaaaaa ttgacgggca taggctgaaa
    31201 ggctttcaac ataacggcgt tggccttcgg catacaaagt atcaaacgcc agcgacgatt
    31261 taccgcttcc tgacaatcct gttaccacca cgagcttgtg gcgcggaatg tccaaatcga
    31321 catttttcaa attatgtgta cgcgcgccgc ggatgcggat ggtgtcgttg tcgtgcgaat
    31381 gttggggatg atggttgcac ataatggatg ccgcctgaaa aataaaggaa aaccgatatt
    31441 gtagcacttt ctcggatgcc gtctgaagcc gcgttcagac ggcatttgtc ggcggaacgc
    31501 ggcggattcc gttataatgg cggcaatttt aacccgcttg aataaaagga tgacaaatga
    31561 accgtcttta cccccacccg attatcgccc gtgagggctg gccgattatt ggcggcggtt
    31621 tggctttgag tctgctggtg tcgatatgtt gcggctggtg gtctttgccg ttttgggtgt
    31681 ttaccgtatt tgcattgcag tttttccgcg accctgcgcg tgagattccg ctaaatcctg
    31741 aagcggtgtt gagcccggtt gacggccgta tcgtggtggt cgaacgcgca cgcgatccgt
    31801 atcgtgatgt cgatgctttg aaaatcagta tttttatgaa cgtgttcaat gtgcattcgc
    31861 aaaaatcgcc tgccgattgt acggtaacga aagtggtcta taacaaaggc aaattcgtga
    31921 atgcggattt ggacaaagcc agcacggaaa acgaacgtaa tgcggtgttg gcgactacgg
    31981 cttcaggtcg tgaaattact tttgttcaag tggccggttt ggtggcgcgc cgtattttgt
    32041 gctacaccca agcaggtgcg aaactgtctc gcggcgaacg ctatggcttt atccgcttcg
    32101 gttcgcgcgt ggatatgtat ctgccggttg acgcgcaggc gcaagtggcg attggcgata
    32161 aagtaaccgg cgtaaaaact gtattggcgc gtctgccgct gactgcgccg caaatcgaat
    32221 ccgagcctga atctgagcca gcttcacaag tggcttcggt tgaaacagcg gcaaacccat
    32281 ctgccgaaca acggcaaatc gaggcagcgg cggctaagat tcaggcggct gtgcaagatg
    32341 tgttgaaaga ttaattttgc gaactgaaat agaaaatatc agtaccatca ttcacacgaa
    32401 tgaggaagtt tggttttttg aatttttgct aatgttcaca ccgttatgtt cacgaaaatg
    32461 ggaatccggg aacttaacgt tacagcgatt tatcggaaac ggctgaaacc gaacgaattg
    32521 gattcccgcc tgcgcgggaa tgatggcaca ttagttacct aaaacttaaa aaaaacagaa
    32581 acctttccgc gtcattccca cgaaagtggg aatctagaac ccaaatgcta aggcgattta
    32641 tcggaaacgg ctgaaaccga agagactgga ttcccgcctg cg
//
LOCUS       DAXIDM010000009        32528 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000009 DAXIDM010000000
VERSION     DAXIDM010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 32528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32528
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.009"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(279..1025)
                     /gene="fabG"
                     /locus_tag="ACFOAE_000350"
     CDS             complement(279..1025)
                     /gene="fabG"
                     /locus_tag="ACFOAE_000350"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HFC6883915.1"
                     /translation="MSTQDLSGKIALVTGASRGIGAAIADTLAAAGVKVIGTATSESG
                     AAAISERLAQWGGEGRVLNSAEPETVENLIADIEKTFGKLDILVNNAGITRDNLLMRM
                     KEEEWDDIMQVNLKSVFRASKAVLRGMMKQRAGRIINITSVVGVMGNAGQTNYAAAKA
                     GLIGFSKSMAREVGSRGITVNCVAPGFIDTDMTRALPEETRQTFTAQTALGRFGDAQD
                     IADAVLFLASDQAKYITGQTLHVNGGMLMP"
     gene            complement(1087..2652)
                     /gene="guaA"
                     /locus_tag="ACFOAE_000351"
     CDS             complement(1087..2652)
                     /gene="guaA"
                     /locus_tag="ACFOAE_000351"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFC6883916.1"
                     /translation="MTQDKILILDFGSQVTQLIARRVREAHVYCELHSFDMPLDEIKA
                     FNPKGIILSGGPNSVYESDYQADTGIFDLGIPVLGICYGMQFMAHHLGGEVQPGNQRE
                     FGYAQVKTIDSELTRDIFDDAPNTLDVWMSHGDKVSKLPDGFAVIGNTPSCPIAMMEN
                     AEKQFYGIQFHPEVTHTKQGRALLNRFVLDICGAQPSWTMPNYIEEAVAKIREQVGSD
                     EVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGKMVMDMFARNLGVKVI
                     HVDAEGQFMEKLAGVTDPEKKRKIIGAEFIEVFDAEEKKLTNAKWLAQGTIYPDVIES
                     AGAKTKKAHAIKSHHNVGGLPENMKLKLLEPLRDLFKDEVRELGVALGLPREMVYRHP
                     FPGPGLGVRILGEVKKEYADLLRQADDIFIQELRNTTDENGTSWYDLTSQAFAVFLPV
                     KSVGVMGDGRTYDYVVALRAVITSDFMTAHWAELPYSLLGRVSNRIINEVKGINRVVY
                     DVSGKPPATIEWE"
     gene            complement(2752..4617)
                     /gene="msbA"
                     /locus_tag="ACFOAE_000352"
     CDS             complement(2752..4617)
                     /gene="msbA"
                     /locus_tag="ACFOAE_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005319 - lipid transporter activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006869 - lipid transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A export permease/ATP-binding protein
                     MsbA"
                     /protein_id="HFC6883917.1"
                     /translation="MIEKLTFGLFKKEDARSFMRLMAYVRPYKIRIIAALIAIFGVAA
                     TESYLAAFIAPLINHGFSAPAAPPELSAAAGIISTLQNWREQFTYMVWGTENKIWTVP
                     LFLIILVVIRGICRFTSTYLMTWVSVMTISKIRKDMFAKMLTLSSRYHQETPSGTVLM
                     NMLNLTEQSVSNASDIFTVLTRDTMIVTGLTIVLLYLNWQLSLIVVLMFPLLSLLSRY
                     YRDRLKHVISDSQKSIGTMNNVIAETHQGHRVVKLFNGQAQAANRFDAVNRTIVRLSK
                     KITQATAAHSPFSELIASIALAVVIFIALWQSQNGYTTIGEFMAFIVAMLQMYAPIKS
                     LANISIPMQTMFLAADGVCAFLDTPPEQDKGTLAPQRVEGRISFRNVDVEYRSDGIKA
                     LDNFNLDIRQGERVALVGRSGSGKSTVVNLLPRFVEPSAGNICIDGIDIADIKLDCLR
                     AQFALVSQDVFLFDDTLFENVRYSRPDAGEAEVLSALQAANLQSLIDSSPLGLHQPIG
                     SNGSNLSGGQRQRVAIARAILKDAPILLLDEATSALDNESERLVQQALERLMENRTGI
                     IVAHRLTTIEGADRIIVMDDGKIIEQGTHEQLMSQNGYYTMLRNISNKDAAVRTA"
     gene            complement(4755..5681)
                     /gene="fabD"
                     /locus_tag="ACFOAE_000353"
     CDS             complement(4755..5681)
                     /gene="fabD"
                     /locus_tag="ACFOAE_000353"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFC6883918.1"
                     /translation="MSFAFFFPGQGSQSLGMMNGFAGHAVVKNTFAEASAILGQDLWA
                     MINGSDAEIIGQTVNTQPIMLAAGVAVYRAYSEAGGKTPAAVAGHSLGEYTALVAAGA
                     LDFADAVKLVRLRAELMQSAVPQGVGAMAAILGLEDEQVKQICAESAQGEVVEAVNFN
                     SPGQIVIAGNAAAVGRAMAAAKEVGAKRALPLPVSVPSHCSLMKPAADKLAEALKTVE
                     IKQPQIRVIHNADVAAYDDADKIKDALVRQLYSPVRWTETVNALVSDGIAESAECGPG
                     KVLAGLAKRINKAAACSALTDAGQVAAFIEAH"
     gene            complement(5775..6182)
                     /locus_tag="ACFOAE_000354"
     CDS             complement(5775..6182)
                     /locus_tag="ACFOAE_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFC6883919.1"
                     /translation="MKRQAFFKLMACAAFLSAVSLRLPVLGACYAILSLYAFALYGID
                     KRRAVRGKRRIPEHRLLLPALFGGWAGAYLGSRIFRHKTAKKRFVVLFRLTVSGNVLA
                     TLILIYSGLNLNQYGVASPCRTICTVCGFVALS"
     gene            complement(6229..7191)
                     /locus_tag="ACFOAE_000355"
     CDS             complement(6229..7191)
                     /locus_tag="ACFOAE_000355"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFC6883920.1"
                     /translation="MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRH
                     IAAENEKTSDLAAEAARRALDATGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGIT
                     NGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFG
                     DGAGAVVLGASDKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKF
                     AVKMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHG
                     NTSAASIPLALDTGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY"
     gene            complement(7218..7421)
                     /locus_tag="ACFOAE_000356"
     CDS             complement(7218..7421)
                     /locus_tag="ACFOAE_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883921.1"
                     /translation="MPSEACLVFRRHFLRLKQRIGNPALPVHGNLHLKTICIPNHTPI
                     PVSVICTLPVLGNHRFFAYNSRI"
     gene            complement(7441..7856)
                     /locus_tag="ACFOAE_000357"
                     /pseudo
     CDS             complement(7441..7856)
                     /locus_tag="ACFOAE_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7883..8134)
                     /locus_tag="ACFOAE_000358"
     CDS             complement(7883..8134)
                     /locus_tag="ACFOAE_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafI family immunity protein"
                     /protein_id="HFC6883922.1"
                     /translation="MKTLEKRMKALDKQMMKFGKSLEGRLDARLIESALDYIHYSERF
                     LAFEILCTYIEDFDVRLTEQESREISFINKEFEIESTSD"
     gene            complement(8270..9325)
                     /gene="plsX"
                     /locus_tag="ACFOAE_000359"
     CDS             complement(8270..9325)
                     /gene="plsX"
                     /locus_tag="ACFOAE_000359"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFC6883923.1"
                     /translation="MITLAVDAMGSDQGLTVTVPGATAFLQAHPDVRLIMTGDEAQLR
                     QALNAAGAPMERIDICHTTQVVGMDEAPQSALKNKKDSSMRVAINQVKEGKAQAAVSA
                     GNTGALMATARFVLKTIPGIERPAIAKFLPSDTDHVTLALDLGANVDCTPEQLAQFAV
                     IGSELVHALHPQKGQPRVGLVNVGTEDIKGTDTVKQTYKLLQNSKLNFIGNIESNGIL
                     YGEADVVVADGFVGNVMLKTIEGAVKFMSGAIRREFQSNLFNKLAAVAALPALKGLKN
                     KLDPRKFNGAILLGLRGIVIKSHGGTDETGFRYALEEAYHEAKSAGLSKIEQGVAEQL
                     AALETAKAVQNENADGL"
     gene            complement(9415..9942)
                     /locus_tag="ACFOAE_000360"
     CDS             complement(9415..9942)
                     /locus_tag="ACFOAE_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase"
                     /protein_id="HFC6883924.1"
                     /translation="MKQKIWYTYDDIHRVIKALAEKIRNADIKYDAMIAIGGGGFIPA
                     RMLRCFLEIPIYAVTTAYYDSDNEGQVTEEVKKVQWLDPVPEALRGKNVLVVDEVDDS
                     RVTMEFCLKELLKEDFGTIGVAVLHEKIKAKAGKIPEGIPYFSGITVDDWWINYPWDA
                     HDIDEHNRLAESSRG"
     gene            complement(10117..10296)
                     /gene="rpmF"
                     /locus_tag="ACFOAE_000361"
     CDS             complement(10117..10296)
                     /gene="rpmF"
                     /locus_tag="ACFOAE_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011765354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFC6883925.1"
                     /translation="MAVQQNKKSPSKRGMHRSHDALTAPALSVDSTTGEVHRPHHISP
                     NGMYRGRKVVKAKGE"
     gene            complement(10330..10833)
                     /locus_tag="ACFOAE_000362"
     CDS             complement(10330..10833)
                     /locus_tag="ACFOAE_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003776445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFC6883926.1"
                     /translation="MSDPNLIDPEIFAAEGQNLQGSFLLEELDERVSSHDYPADRQTK
                     ISFTLTGGRDRLQRLFLDLNVKADMPLICQRCIKPMPFMLDESSRIVLFSNEESLDES
                     MLADEELEGILIEKELDVRTLVEDQILMSLPFSPRHEDCGSNGTPEKADRDKPNPFAV
                     LAGLKSN"
     gene            10981..11571
                     /locus_tag="ACFOAE_000363"
     CDS             10981..11571
                     /locus_tag="ACFOAE_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030428 - cell septum [Evidence IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family nucleotide pyrophosphatase"
                     /protein_id="HFC6883927.1"
                     /translation="MGLELPLILGTSSVFRREQMERLGIAFQAASPDFDETPMLGESA
                     PQTALRLAEGKARSLAGRFPEALIVGADQVAWCDGRQWGKPMNLANAQKMLMHLSGRE
                     IEFYSAVVLLNTVTGRMQRHIDKTVVVMRKLDELHILRYLEREPDAVYCSCALKSEAL
                     GALLIERIESTDPNALIGLPVFRLVDFLKNEGVEVL"
     gene            11633..12343
                     /locus_tag="ACFOAE_000364"
     CDS             11633..12343
                     /locus_tag="ACFOAE_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HFC6883928.1"
                     /translation="MSPVLYLIPTPLGTPDTPCLLPHEQQAVVGLTDFVVEAEKTARA
                     HLKHLGVTMPIRELNLQTLNEHTDLKTLPELLKPLQEGRSMGIVSEAGCPAVADPGAN
                     LVALAHKHGFEVRPLVGPSSLLLALMASGANGQSFAFKGYLPSEKNERIQSLKALEQR
                     SRQQNETQLFIETPYRNDVLLADAVENLHPETRLCTATDLTLPTQSVVSKTVADWRRM
                     KEMPNLKKRPTIFVMYAG"
     gene            complement(12424..14061)
                     /gene="yidC"
                     /locus_tag="ACFOAE_000365"
     CDS             complement(12424..14061)
                     /gene="yidC"
                     /locus_tag="ACFOAE_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFC6883929.1"
                     /translation="MDFKRLTAFFAIALVIMIGWEKMFPTPKPVPAPQQTAQQQAVTA
                     SAEAALAPATPITVTTDTVQAVIDEKSGDLRRLTLLKYKATGDENKPFILFGDGKEYT
                     YVAQSELLDAQGNNILKGIGFSAPKKQYSLEGDKVEVRLSAPETRGLKIDKVYTFTKG
                     SYLVNVRFDIANGSGQTANLSADYRIVRDHSEPEGQGYFTHSYVGPVVYTPEGNFQKV
                     SFSDLDDDAKSGKSEAEYIRKTPTGWLGMIEHHFMSAWILQPKGGQSVCAAGDCSIDI
                     KRRNDKLYSASVSVPLAAIPAGAKAETAVNLYAGPQTTSVIANIADNLQLAKDYGKVH
                     WFASPLFWLLNQLHNIIGNWGWAIIVLTIIVKAVLYPLTNASYRSMAKMRAAAPKLQA
                     IKEKYGDDRMAQQQAMMQLYTDEKINPLGGCLPMLLQIPVFIGLYWALFASVELRQAP
                     WLGWITDLSRADPYYILPIIMAATMFAQTYLNPPPTDPMQAKMMKIMPLVFSVMFFFF
                     PAGLVLYWVVNNLLTIAQQWHINRSIEKQRAQGEVVS"
     gene            complement(14233..14454)
                     /gene="yidD"
                     /locus_tag="ACFOAE_000366"
     CDS             complement(14233..14454)
                     /gene="yidD"
                     /locus_tag="ACFOAE_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFC6883930.1"
                     /translation="MNFLLSKLLLGLIRFYQYCISPLIPPRCRYTPTCSQYAVEAVKK
                     YGAFKGGRLAIKRIARCHPFGGHGHDPVP"
     gene            complement(14520..14885)
                     /gene="rnpA"
                     /locus_tag="ACFOAE_000367"
     CDS             complement(14520..14885)
                     /gene="rnpA"
                     /locus_tag="ACFOAE_000367"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFC6883931.1"
                     /translation="MDYRFGRQYRLLKTDDFSSVFAFRNRRSRDLLQVSRSNGNGLDH
                     PRIGLVVGKKTAKRANERNYMKRVIRDWFRLNKNRLPPQDFVVRVRRKFDRATAKQAR
                     VELAQLMFGNPATGCRKQA"
     gene            complement(14888..15022)
                     /gene="rpmH"
                     /locus_tag="ACFOAE_000368"
     CDS             complement(14888..15022)
                     /gene="rpmH"
                     /locus_tag="ACFOAE_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003816025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFC6883932.1"
                     /translation="MKRTYQPSVTKRKRTHGFLVRSKTRGGRAVLAARRAKGRKRLAV
                     "
     gene            15310..16866
                     /gene="dnaA"
                     /locus_tag="ACFOAE_000369"
     CDS             15310..16866
                     /gene="dnaA"
                     /locus_tag="ACFOAE_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFC6883933.1"
                     /translation="MTLAEFWPLCLRRLHDMLPQGQFAQWIAPLTVGEEGGVWVVYGK
                     NQFACNMLKSQFAGKIEAVREELAAGRSAFVFKPGEGVRYEMAAVEGAVEPAEPSLHA
                     VSEEMPVQEVLLDELPSEEPAKSVQAKTAADILAERMKNLPHEPRHTAGSASRPESEV
                     LAKARTDAQRDAEEARYEQTNLSPDYTFDTLVEGKGNRLAAAAAQAIAESPGQSYNPF
                     FLYGSTGLGKTHLVQAVGNELLKNRPDAKVRYMHSDDYIRSFMKAVRNNTYDVFKQQY
                     KQYDLLIIDDIQFIKGKDRTMEEFFYLYNHFHNEKKQLILTCDVLPAKIEGMDDRLKS
                     RFSWGLTLELEPPELEMRIAILQKKAEAAGISIEDEAALFIANLIRSNVRELEGAFNR
                     VGASSRFMNRPVIDIDLARTALQDIIAEKHKVITADIIIDAVAKYYRIKISDVLGKKR
                     TRNIARPRQVAMSLTKELTTLSLPSIGDSFGGRDHTTVMHGIRAVAKLREEDPELAQD
                     YEKLLILIQN"
     gene            17101..18204
                     /gene="dnaN"
                     /locus_tag="ACFOAE_000370"
     CDS             17101..18204
                     /gene="dnaN"
                     /locus_tag="ACFOAE_000370"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFC6883934.1"
                     /translation="MLILQAERDSLLKPLQAVTGIVERRHTLPILSNVLIEGKGGQTK
                     LLATDLEIQIDTAGPEGGAGDFRITTNAKKFQDILRALPAGALVSLDWDDSRLTLKAG
                     KSRFALQTLPAADFPMMNVGEDISATFSLEQERFKTMLSQVQYSMAVQDIRYYLNGLL
                     MQVEGSQLRLVATDGHRLAYAACAIDADLPRAEVILPRKTVLELFKLLNNPDDPIQIE
                     LLDKQVRFQCNGTTIVSKVIDGKFPDFNRVIPLDNDKIFVLSRAELLGALERASILAN
                     EKFRGARLFLQPGLLSVVCSNNEQEEAREEIEIAYQGGELEVGFNIGYLMDVLRNIHS
                     DDMQLAFGDANRSTLFTVPNNPNFKYIVMPMRI"
     gene            complement(18173..18442)
                     /locus_tag="ACFOAE_000371"
     CDS             complement(18173..18442)
                     /locus_tag="ACFOAE_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883935.1"
                     /translation="MPSETFPFQTAWFYSNLNRADRSQKHTFAIPAQALPLYAPNPNP
                     PHSRRHYLSDSRTKPRIRLHGSGYISNTGIVFRKTVKSASASQYI"
     gene            complement(18467..20524)
                     /gene="ppk1"
                     /locus_tag="ACFOAE_000372"
     CDS             complement(18467..20524)
                     /gene="ppk1"
                     /locus_tag="ACFOAE_000372"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009358 - polyphosphate kinase complex
                     [Evidence IEA];
                     GO_function: GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006799 - polyphosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HFC6883936.1"
                     /translation="MPEQNRILCRELSLLAFNRRVLAQAEDKNVPLLERLRFLCIVSS
                     NLDEFFEVRMAWLKRENKLHPRRRLDNGKMPSETIADVTEAARSLIRHQYDLFNNVLQ
                     PELARESIHFYRRRNWTGAQKKWIEDYFDRELLPILTPIGLDPSHPFPRPLNKSLNFA
                     VELDGTDAFGRPSGMAIVQAPRILPRVVPLPSELCGGGHGFVFLSSILHAHVGKLFPG
                     MNVKGCHQFRLTRDSDLTVDEEDLQNLRAAIQNELHDREYGDGVRLEVADTCPAYIRD
                     FLLAQFKLTAAELYQVKGPVNLVRLNAVPDLVNRPDLKFPTHTPGRLKALGKTASIFD
                     LVRQSPILLHHPYQSFDPVVEMMREAAADPDVLAVKMTIYRTGTRSELVRALMKAALA
                     GKQVTVVVELMARFDEANNVNWAKQLEEAGAHVVYGVFGYKVHAKMALIIRREDGVLK
                     RYAHLGTGNYHQGTSRIYTDFGIITADEQITADVNTLFMEITGLGKPGRLNKLYQSPF
                     TLHKMVIDRIARETEHAKAGKPARITAKMNSLIEPTVIEALYRASAAGVQIDLIVRGM
                     CTLRPGVKGLSENIRVRSIIGRQLEHARVYCFHNNGADDTFISSADWMGRNFFRRIET
                     AAPITAPELKKRVIREGLEMALADNTHAWLMQPDGGYIRAAPAEGESEADLQNDLWTL
                     LGG"
     gene            complement(20693..21136)
                     /locus_tag="ACFOAE_000373"
     CDS             complement(20693..21136)
                     /locus_tag="ACFOAE_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HFC6883937.1"
                     /translation="MPFRLFLGILCGLSMVAPVYAQGQPDAINAYIQKKKVIVDTSKA
                     ELCFADDRQCHPVLIGVATPKGTFGLTLNSTDKPGYGGEVIGFKQEGDFLFALHRVWN
                     QIPSERRNERIASPSVSDRIMTNGCINVSDAVYEKLRHYFVLEVI"
     gene            complement(21143..21658)
                     /locus_tag="ACFOAE_000374"
     CDS             complement(21143..21658)
                     /locus_tag="ACFOAE_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HFC6883938.1"
                     /translation="MKIKQIVKPGLAVLAAGVLSACATKSNVKADGTTDNPVFPKPYS
                     VTLDNKRGTFPTYDELDQMRPGLTKDDIYKILGRPHYDEGMYGVREWDYLFHFHTPGV
                     GIDPENTSGVEDVTTCQYKVIFDKDKFARSFYWNPVFPKDAACPPPAPKAEPQVIIRE
                     IVPAKPKRIRQ"
     gene            21928..24558
                     /gene="leuS"
                     /locus_tag="ACFOAE_000375"
     CDS             21928..24558
                     /gene="leuS"
                     /locus_tag="ACFOAE_000375"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFC6883939.1"
                     /translation="MQEQYQPAAIEPAAQKKWDDERIFNVSEDASKPKYYCLSMFPYP
                     SGKLHMGHVRNYTIGDVLSRFKRLNGFNVMQPMGWDAFGMPAENAAMKNNVAPAAWTY
                     DNIEYMKTQLKSLGFAIDWARETATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNWDP
                     VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKT
                     MQRNWIGKSRGMTVRFAVSDDSKQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPL
                     ATAAAADKPELQEFIAECKAGSVAEADMATMEKKGVPTGRYVVNPLNGDKLEVWIANY
                     VLWGYGDGAVMAVPAHDERDFEFATKYNLPKKQVIAIGDNTFDANQWQEWYGDKENGV
                     LVNSGDLDGMNFQTAFDAIAAKLQSQRAGEPKTQYRLRDWGISRQRYWGCPIPIVHCE
                     KCGDVPVPADQLPVVLPENVVPDGMGSPLAKMPEFYETACPSCGGAAKRETDTMDTFM
                     ESSWYFFRYMSPKFSDGMVSAEAAKYWGAVDQYIGGIEHAILHLLYARFFTKLMRDEG
                     LVSVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPVFAVLKADG
                     LPVVISGTEKMSKSKNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAH
                     RFLRRLWRTVYEYLKQGEAVKAFAGSQDGLSKELKDLRHKLHSTIAKVSDDYGRRQQF
                     NTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLETAVRLLWPIVPHICETLWSELNGAK
                     LWEAGWPTVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALATEGAVKFM
                     EGKPAKKIIVVPGRLVNIVV"
     gene            24693..25484
                     /locus_tag="ACFOAE_000376"
     CDS             24693..25484
                     /locus_tag="ACFOAE_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnI domain-containing protein"
                     /protein_id="HFC6883940.1"
                     /translation="MNLFFDTELGKQQNKATHKIRVMSEAWLEKNGYCPCCGSKPMQR
                     FANNKPVADLFCPNCHEQYELKSKNQKTIGNSVPDGAYHTMLERIRSDTNPNFFFLAY
                     KKADYSIRQLVLVPKHFITPDMIIPRNKGIKNRPHHIMCSINLAPLPESGKIFLIDDS
                     RIIEPETVLKKWQSNLFLRNQNAERKGWLLAVMKCIDQLPEEFTLSQMYGFEDKLSIQ
                     FPQNNHIRDKIRQQLQILRDQNTIEFIGRGLYKKIDKLRPTPKAF"
     gene            25451..25621
                     /locus_tag="ACFOAE_000377"
                     /pseudo
     CDS             25451..25621
                     /locus_tag="ACFOAE_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
     gene            25614..26424
                     /locus_tag="ACFOAE_000378"
                     /pseudo
     CDS             25614..26424
                     /locus_tag="ACFOAE_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751586.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
     gene            26421..26975
                     /locus_tag="ACFOAE_000379"
     CDS             26421..26975
                     /locus_tag="ACFOAE_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883941.1"
                     /translation="MIIGGIGGARTQTGLRFEERTDLRKLFEEIPGYDLRKTYDNAGY
                     EVWFNGELKAYCFKKYEFYRFLKRPGYSINWKDHLSKRLLPDNGLFIIIRDTLFIIEI
                     KFQQTPGSVDEKLQICDFKRKQYTKLVHSLGWRVEYVYVLNDWFTKPEYKDVLDYIIS
                     VNCHYQFNTIPLRWFGLPDGETNE"
     gene            complement(27747..28058)
                     /locus_tag="ACFOAE_000380"
     CDS             complement(27747..28058)
                     /locus_tag="ACFOAE_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC6883942.1"
                     /translation="MKYKSEALAAIHEMMEGAYNIGAIDKKTMRGFDKSCLTEIKPLS
                     GGDIKAIREKEALSQAAFAIYLNVGKNHVSAWERGVKKPSGAALKLLTIVKNKGIEAI
                     A"
     gene            complement(28055..28422)
                     /locus_tag="ACFOAE_000381"
                     /pseudo
     CDS             complement(28055..28422)
                     /locus_tag="ACFOAE_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582268.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            28921..29163
                     /locus_tag="ACFOAE_000382"
     CDS             28921..29163
                     /locus_tag="ACFOAE_000382"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883943.1"
                     /translation="MDGFPLIPYGASVFPASYFPLGIPDLVVVQLYFHVFFAVFSDAV
                     KNQVSSIRADWTGLYGQEGGRQDNNQPEILVLIGIG"
     gene            complement(29223..29308)
                     /locus_tag="ACFOAE_000383"
     tRNA            complement(29223..29308)
                     /locus_tag="ACFOAE_000383"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29272..29274),aa:Leu,seq:gag)
     gene            complement(29322..29672)
                     /gene="secG"
                     /locus_tag="ACFOAE_000384"
     CDS             complement(29322..29672)
                     /gene="secG"
                     /locus_tag="ACFOAE_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFC6883944.1"
                     /translation="MEAFKTLIWIVNIISALAVIVLVLLQHGKGADAGATFGSGSGSA
                     QGVFGSAGNANFLSRSTAVAATFFFATCMAMVYIHTHTTKHGLDFSNVQQTQQAPKPV
                     SNTEPSAPVPQQQK"
     gene            complement(29679..30452)
                     /gene="tpiA"
                     /locus_tag="ACFOAE_000385"
     CDS             complement(29679..30452)
                     /gene="tpiA"
                     /locus_tag="ACFOAE_000385"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFC6883945.1"
                     /translation="MYHQIGMWDQKWVIGNWKMNGRLQNNNSLMHRFRILPTAERVLI
                     GLAAPTVYLLQLHNAMQIVLNNRILTCAQDVSRFPNNGAYTGEVSAEMLADTGTDIVL
                     IGHSERSLYFGEKNEIQRRKMENVLNVGLIPLLCVGESLEEREAGKEHEVIAHQLSIL
                     QGLDTKNIAVAYEPVWAIGTGKVATVEQIADMHAFIYKEILSLCGSDVKIRVLYGGSV
                     KADNAADIFAVPYVDGALVGGASLSYDSFTAIISAAQNA"
     gene            30612..31139
                     /locus_tag="ACFOAE_000386"
     CDS             30612..31139
                     /locus_tag="ACFOAE_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFC6883946.1"
                     /translation="MYATIGDVMHALHFSASDKAALYREVLPQIESVVADEADWVANL
                     ANTAAVLKEAFGWFWVGFYLVDTRSDELVLAPFQGPLACTRIPFGRGVCGQAWAKGGT
                     VVVGDVDAHPDHIACSSLSRSEIVVPLFSDGRCIGVLDADSEHLAQFDETDALYLGEL
                     AKILEKRFEASRQAA"
     gene            31242..31898
                     /locus_tag="ACFOAE_000387"
     CDS             31242..31898
                     /locus_tag="ACFOAE_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HFC6883947.1"
                     /translation="MDFEKARFNMVEQQIRPWDVLDFDVLDALEEIPRERFVDASLQG
                     LAYADTELPLANGHKMLEPKVVARLAQGLKLTKNDTVLEIGTGSGYAAALLAKLAGRV
                     VSDDIDAEQQNRAKAVLDGLGLDNIDYVQNNGLTELSAGAPFDAVYVGGAVNIVPDVL
                     KEQLKDGGRMVVIVGRKPVQRALLITRKGDVFEEKVLFDTLVAHLDDKDADPFGGFDF
                     "
     gene            31978..32301
                     /locus_tag="ACFOAE_000388"
     CDS             31978..32301
                     /locus_tag="ACFOAE_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFC6883948.1"
                     /translation="MDIVQLGSAELKAWMDEGRMFCLLDVRTDEETAVCSLPNALHIP
                     MNLIPLRQNELPDDVPLVVYCHHGIRSLHTAMYLADAGFENLYNLQGGIDAWAAEIDG
                     NMMRY"
     gene            complement(32312..>32528)
                     /locus_tag="ACFOAE_000389"
     CDS             complement(32312..>32528)
                     /locus_tag="ACFOAE_000389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883949.1"
                     /translation="SLHIENAAQANFQFASLVLALSHGERGLGCRLPLRFRQILTSLI
                     PRFSFAEAALSDDLLEHHRYTHLRNAV"
BASE COUNT         7135 a         7796 c         9480 g         8117 t
ORIGIN      
        1 cgcctaaaag gtgacccgga tgcctgatta tcaggtgtcc gggcaggatt aaaggggtat
       61 ttgggtagaa ttaggcggta tttggggcga aaacagctga aaacagctga aaacctgtgt
      121 tggggtttcg gctgtcggga gggaaaggaa ttttgcaaag gtctcagctt gtgcctgagc
      181 cgcatgggca gggcggggtg tggtgtgtgt tcattttgcc tgagaatgca aatgccgtct
      241 gaaagggctt cagacggcat ggttgaaaaa gttgtctgtt aaggcatcag cataccgccg
      301 ttgacgtgca gcgtttggcc ggtgatgtat tttgcttggt cggaagcgag gaacagaacc
      361 gcatcggcga tgtcttgcgc gtcgccgaat ctgcccaagg cggtttgggc ggtaaaggtt
      421 tggcgggttt cttccggcag ggcgcgtgtc atgtcggtat cgataaagcc aggggcgacg
      481 cagttgacgg taatgccccg gctgccgact tcgcgcgcca tggatttgga gaaaccgatt
      541 aagcctgctt ttgccgcggc atagttggtt tgaccggcat tgcccatcac gccgacgacg
      601 gatgtgatgt tgatgatacg gccggcgcgc tgcttcatca tgccgcgcaa gacggctttg
      661 gaggcgcgaa agacggattt gaggttgacc tgcatgatgt cgtcccactc ttcttctttc
      721 atacgcatca ggaggttgtc gcgggtgatg ccggcgttgt tgaccagaat atcgagtttg
      781 ccgaacgttt tttcgatgtc ggcaatcagg ttttcgacgg tttcgggttc ggcggaattt
      841 aatacgcggc cttcgccgcc ccattgcgcc aaccgctcgc taatcgccgc cgcaccgctc
      901 tcactggtcg ccgtaccgat gactttgaca ccggctgccg ccagtgtgtc ggcaattgct
      961 gcaccgatac cgcgcgaggc gcctgttacc aaagcgattt tgccgcttaa atcttgtgtg
     1021 ctcatatttt ttcctttttt ccgataatcg aaagactgcg ccggacggtg cagccctgtt
     1081 tgctggttat tcccactcga tggtggcagg cggtttgccg ctgacatcgt acaccacgcg
     1141 gttgatgcct ttgacttcgt tgatgatgcg gttggacacg cgtccgagca gtgagtaagg
     1201 caactcagcc caatgtgcgg tcataaagtc gctggtgatg actgcgcgca gtgcgacgac
     1261 gtagtcgtaa gtgcgtccgt cgcccattac gccgacggat ttcacaggca ggaacacggc
     1321 gaaggcttgg ctggtcaggt cgtaccaaga cgtgccgttt tcgtcggtgg tgttgcgtaa
     1381 ttcttgaata aaaatatcgt ctgcttgacg caataagtcg gcgtattctt ttttcacttc
     1441 gcccaagatg cgcacgccca aaccgggacc ggggaaggga tggcggtaca ccatttcgcg
     1501 cggcagaccc aaagccacgc ccagttcgcg cacttcgtct ttgaacaaat cgcgcaacgg
     1561 ctcaagcagc ttgagcttca tgttttcagg caggccgccg acattgtggt gggatttgat
     1621 ggcgtgggct tttttggttt tcgcgcctgc ggattcgatt acgtcagggt aaatcgtgcc
     1681 ttgcgccagc catttggcgt tggtgagttt tttttcttca gcatcaaata cttcgataaa
     1741 ttccgcaccg atgattttgc gttttttctc gggatcggta acgccggcga gtttctccat
     1801 aaactgccct tcggcatcga cgtgaatcac tttcacaccc aaattgcggg cgaacatatc
     1861 catcaccatt ttgccttcgt tcaggcgcaa caaaccgtga tcgacgaaca cgcaggtcag
     1921 ttggtcgccg atggcgcggt gaatcagcgc ggcggctacg gaagagtcca cgccgccgga
     1981 caaacccaaa atcacttcgt cgctgccgac ctgttcgcgg attttggcaa cggcttcttc
     2041 gatgtagttc ggcatcgtcc agctcggttg tgcgccgcaa atatccaaga caaagcggtt
     2101 caacagggcg cggccttgtt tggtgtgggt cacttcaggg tggaattgga taccgtagaa
     2161 ttgtttctca gcattttcca tcatggcaat cgggcaggac ggggtgttgc cgatgacggc
     2221 gaagccgtcg ggcagtttgg acactttgtc gccgtggctc atccatacgt cgagtgtgtt
     2281 gggcgcgtcg tcgaaaatat cgcgggtcag ttcgctgtcg atggttttga cttgcgcata
     2341 accgaattcg cgctggttgc cgggctgcac ttcgccgccc aagtggtgcg ccataaactg
     2401 cattccgtag cagatgccca aaaccggaat gcccaaatca aaaataccgg tatcggcctg
     2461 atagtcggat tcgtaaacgg aattagggcc gccggaaagg atgatgcctt tggggttgaa
     2521 ggctttgatt tcgtccaaag gcatatcgaa ggaatgcagt tcgcagtaaa cgtgggcttc
     2581 gcgcacgcgg cgggcaatca gctgggtaac ttgcgaaccg aagtcgagga tgaggatttt
     2641 gtcttgggtc ataatgggtt ttacagtgat tgaagataat cggatgggtc ggcggatata
     2701 gtgccgtctg aaagggtcgg ggcgattata ccatttcgga cggcattttg tttatgccgt
     2761 ccggacggcg gcatctttgt ttgagatatt gcgtaacatc gtgtagtagc cgttttggga
     2821 catcagttgt tcgtgtgtgc cttgttcgat gattttgccg tcgtccatta cgatgatgcg
     2881 gtcggcccct tcgatggtgg tcaggcggtg ggcgacgatg atgccggtgc ggttttccat
     2941 caggcgttcg agcgcttgtt ggacgaggcg ttcggattcg ttgtctaatg cgctggtggc
     3001 ttcgtccaat aataatatcg gcgcgtcttt caaaatggcg cgggcgatgg cgacgcgttg
     3061 ccgctgtccg ccggacaagt tgctgccgtt cgatccgatg ggctggtgca gtccgagcgg
     3121 ggagctgtca atcaggcttt gcaggttggc ggcttggagg gcggacagga cttcggcttc
     3181 gcctgcatcg ggacggctgt atcggacgtt ttcaaacagg gtgtcgtcaa acaggaatac
     3241 gtcttgggag acgagggcga attgggcgcg caggcagtcg agtttgatgt cggcgatgtc
     3301 gataccgtct atgcagatgt tgccggcaga cggttcgaca aagcggggca gcaggttgac
     3361 gacggtggat ttgccgctgc cggaacgtcc gaccagggcg acgcgttcgc cttgtctgat
     3421 gtcgaggttg aagttgtcga gggctttgat gccgtccgaa cggtattcga catcgacgtt
     3481 gcggaagctg atacgccctt cgacacgctg cggcgcgagc gtgcctttgt cctgttcggg
     3541 cggggtgtcg agaaatgcac atacgccgtc ggcggcgagg aacatcgtct gcatagggat
     3601 gctgatgttg gcaaggcttt tgatgggtgc gtacatttgc agcatcgcga cgatgaatgc
     3661 cataaattcg ccgatggtgg tgtagccgtt ttggctttgc cacagggcga tgaagatgac
     3721 aacggcgagg gcaatcgagg caatcagttc gctgaacggg gaatgtgccg ccgttgcctg
     3781 cgtgattttt ttgctgaggc ggacgatggt gcggttgacc gcgtcaaacc ggtttgccgc
     3841 ctgcgcctgc ccgttgaaca gcttgacgac gcggtgtccc tgatgggttt cggcaatcac
     3901 gttgttcatc gtgcctatgc ttttttgcga gtcggaaatg acgtgcttca gacggtcgcg
     3961 gtagtagcgc gagagcaggg agagcagggg gaacatcagg acaacgatga ggctgagctg
     4021 ccagttgagg taaagcagga cgatggtcag gccggtaaca atcatcgtgt cgcgcgtgag
     4081 gacggtgaag atgtcgctgg cgttactgac cgactgttcg gtcaggttga gcatattcat
     4141 cagtacggtg ccggacggcg tttcctgatg gtagcgggag gaaagggtca gcattttggc
     4201 aaacatatct ttgcggattt tgctgatggt catcacggag acccaagtca tcagataggt
     4261 gctggtaaag cggcagatgc cacggatgac gacgaggatg atgaggaaga gggggacggt
     4321 ccagattttg ttttccgtcc cccaaaccat ataggtaaac tgttcgcgcc agttttgcag
     4381 ggtggaaatg atgccggcgg cggcagacag ctcgggcggc gcggcaggtg cggaaaagcc
     4441 gtggttaatc aggggggcga tgaaggcggc aaggtagctt tcggtggcgg caacgccgaa
     4501 aatggcaatc agggcggcaa tgatgcggat tttgtagggg cggacgtacg ccatcaggcg
     4561 cataaagctg cgcgcgtctt cttttttaaa cagtccgaaa gtcagttttt ctatcatatc
     4621 ggtagggcgg gaactgcaac ggcagccgct gtcggtggtt tggtcgggat ggattatagc
     4681 gtaaatatgg ggctgccgcc gttcggacat gaaaagcagc ctgaagaggg caggctgctt
     4741 tttgcagaac gaagtcagtg cgcttcgata aaggcggcaa cctgtccggc atcggtcagt
     4801 gcgctgcacg cggcggcttt gttgatgcgt tttgccaagc ctgccaacac tttgcccggg
     4861 ccgcattcgg cggattcggc aatgccgtct gaaacgaggg cgttgacggt ttccgtccag
     4921 cgtacggggc tgtaaagctg gcggacgagc gcgtctttga ttttgtcggc atcatcgtag
     4981 gcggcaacgt cggcgttgtg gatgacgcgg atttgcggct gcttgatttc aacggttttc
     5041 agggcttcgg caagtttgtc ggcggcgggt ttcatcaggc tgcaatggga aggtacggac
     5101 acgggcagcg gcagggcgcg tttggcaccg acttctttgg cggcagccat ggcgcgtccg
     5161 acggcggcgg cgttgcctgc aatcacgatt tgcccgggcg agttgaagtt gacggcttcg
     5221 accacttcgc cctgtgcgga ttcggcgcaa atttgtttta cctgttcatc ttccaagccg
     5281 agaatcgccg ccattgcgcc cacgccttgc ggtacggcgg actgcatcag ttcggcgcgc
     5341 aggcgcacga gtttgaccgc gtcggcaaaa tccaatgcgc cggcggcaac gagtgcggtg
     5401 tattcgccga ggctgtgtcc ggcaacggcg gcaggcgttt tgccgcccgc ttccgaatag
     5461 gcgcggtaaa cggcaacgcc ggcggcgagc ataatgggct gggtgttgac ggtttgaccg
     5521 atgatttcgg catcgctgcc gtttatcatc gcccacaagt cctgccccaa tatggcggag
     5581 gcttcggcaa aggtgttttt aacgacggcg tgtccggcaa agccgttcat cataccgagg
     5641 ctttgggaac cttgtccggg aaaaaagaag gcaaaagaca tagtattcct ttatttggtt
     5701 ggataatcag gtattctgcc cgagttttac gaaaaattca ggcgggacaa aataatatag
     5761 tggattaaca aaaatcagga caaggcgacg aagccgcaga cagtacaaat agtacggcaa
     5821 ggcgaggcaa cgccgtactg gtttaaattt aatccactat aaatcaggat gagggtcgcc
     5881 aggacattgc ccgaaacagt cagacggaac agcacaacaa aacgcttttt cgccgtttta
     5941 tgcctgaata tcctgctgcc caagtatgcg cccgcccaac cgccgaacaa ggcaggcagc
     6001 agcaggcggt gttcgggaat gcggcgtttt ccccgcacgg cacgccgttt gtcgatgccg
     6061 taaagtgcaa acgcatagag ggacaatatt gcgtaacacg cgcccaatac ggggaggcgc
     6121 agcgaaacgg cagacagaaa tgccgcacac gccatcagtt tgaagaaagc ctgccgcttc
     6181 atgatatggg aaatgccgtc tgaaagcctg tttcagacgg catcgggttc aatattgcaa
     6241 cagcaccgcg ccccacgcga aaccgccgcc gatgccttcg agcagcaggt tttgaccgcg
     6301 tttgatttgt ccgctgcgga tgcccgtatc caaagccagc ggaatcgagg cggcggatgt
     6361 gttgccgtgg tcttggacgg tcaggacgac tttgtccata ctcaaaccta aatgtttcgc
     6421 ggtcgattcg ataatgcggc ggtttgcctg atgcggcacg atccagtcga tttgagcggc
     6481 ggtgtaaccg gcttcttcga taacgtcatc ggcgattttg gacagcattt tgacggcaaa
     6541 cttgaacacg ccgggaccgt ccatcgaaat gtacggcgaa ccggaaactt tgccgcaggc
     6601 gatttgcccg gggacgttta agagtttcag ataattgccg tcggctttga gtttgctgtg
     6661 gatgatgccc ggtttgtcgg acgcgcctaa aaccaccgcg cccgcaccgt cgccgaacaa
     6721 tacgcaggtt gtgcggtcgt tccagtctac aatgcgactg aaggtttccg cgccgatgac
     6781 cagcgcgttt tttgccatgc cgcttttgat gtaggcgttt gccgtggtca gcgcgtacat
     6841 aaagcccgca cacaccgcct gtacgtcaaa cgcggggcag ccgttggtga tgcccagttt
     6901 ttgttggacg atggtggcgg tagaaggaaa ctgcatatcc ggcgttgccg tcgccacaat
     6961 aattaaatcg atttcgccgc tgtctaatcc ggttgcatcc agtgcgcggc gggctgcttc
     7021 ggcggcaaga tcgctggttt tctcattttc ggctgcaata tggcggaact tgatgcccgt
     7081 acgcgcggta atccactcgt cagaggtatc taccttttgg gcaaggtcgt cattgctgac
     7141 gcggttggcg ggaagatagc tgcccgtgcc ggaaattttt gcatactgca tgggaacggc
     7201 ctttttagag agttggttca gattcggcta ttgtaagcga aaaaccgatg attgcccaat
     7261 acgggcaggg tgcaaatgac ggaaacaggg atgggggtgt ggtttgggat acagatggtt
     7321 ttcagatgca gattgccgtg gacaggcagg gcggggttgc cgatacgctg ttttaagcga
     7381 aggaaatgcc gtctgaaaac caaacatgct tcagacggca ttttgattgt tggttttcca
     7441 tcaaattatt ggtgccggtg tttgtttttg tatcataaat tcagaaatta tattttgaat
     7501 tgtagaaata tttttagaga tatgctcaat agggtaggaa tctcccaaga tttcccttgc
     7561 cttcccgctg taattttctg ttttaaggtt tttgacttca atatccccgt cttctaaaat
     7621 tgtttgaatc attggcaaat aatatccttt ttcaaaatag atagttaatt cggtatcgcc
     7681 aaattccggc tcggggatga ttctgaaaac aaggacgccg gcttttttct caaaatttga
     7741 tacggaaaaa agtgattgat ttccctaatg tcaggatttt ccaaaacggg gatttggatt
     7801 cgctctccat tatctgtaat aaaaaatccg ccaaaaacga ccgtcgatgt tttcatgttt
     7861 atcaacccat tggctttatt ggttaatcgg acgtgctttc tatctcaaat tccttgttga
     7921 taaaagaaat ttcccgggat tcttgttccg tcagccggac atcgaaatct tcgatataag
     7981 tacacaggat ttcaaaagcc aaaaaacgtt ccgaataatg aatataatcc aatgcggatt
     8041 caatcagacg ggcatcaagc ctgccttcaa gggattttcc gaacttcatc atctgtttgt
     8101 ctagagcttt catccgtttt tctaatgtct tcatttttca aatactcctt attttacagg
     8161 gaagtatttg ggaagtgccg gacaggcgca tcgccgtccg cgcccgcagg tttggtgcgg
     8221 gcggatgccg tctgaaaggg gcgggggcgt tcagacggca tcgtgtgtgt tacagaccgt
     8281 cggcattttc gttttggacg gctttggcag tttcgagtgc ggcgagttgt tcggcaacgc
     8341 cttgttcgat tttggaaagg ccggcggact tggcttcgtg gtaggcttct tcgagtgcgt
     8401 agcggaaacc ggtttcgtct gtgccgccgt ggcttttgat gacgatgccg cgcagcccga
     8461 gcaggatggc cccgttgaat ttgcgcggat cgagtttgtt tttcagccct ttgagggcgg
     8521 gtagggcggc aacggcggca agtttgttga acaggttgct ttggaattcg cggcggatgg
     8581 ctccgctcat gaatttgacc gcgccttcga tggttttgag catgacgttg ccgacaaagc
     8641 cgtcggcgac gacgacatct gcttcgccgt acaggatgcc gttgctttcg atgttgccga
     8701 taaagttgag tttgctgttt tgcagcagtt tgtaggtttg tttgacggtg tccgtacctt
     8761 tgatgtcttc cgtgccgacg ttgaccagcc cgacacgcgg ctgtcctttt tgaggatgga
     8821 gtgcgtggac gagttcgctg ccgataacgg caaattgggc gagctgttcg ggcgtgcagt
     8881 cgacgtttgc gccgaggtcg agggcgaggg taacgtggtc ggtgtcggaa ggaaggaatt
     8941 tggcgatggc ggggcgttcg atgccgggaa tggttttgag gacgaaacgt gcggttgcca
     9001 tgagcgcgcc cgtgttgcct gcggatacgg cggcttgggc tttgccttct ttaacctggt
     9061 tgatggcgac gcgcatggag gagtcttttt tgtttttcag ggcggattgc ggggcttcgt
     9121 ccatgccgac aacttgggtg gtatggcaga tgtcgatgcg ttccatcggc gcgcctgctg
     9181 cgttcagggc ttggcggagc tgtgcttcgt cgccggtcat aatcaggcgg acatcggggt
     9241 gtgcttggag gaatgcggtt gcgccgggta cggtaacggt aagtccttgg tcgctgccca
     9301 tggcatctac ggccaacgta atcatagggg tttctccggt gggttttcgg tctgcggcag
     9361 gggtcgtgcg ggcttcagac ggcatcggtt cggaaaatat gccgtctgaa agggtcagcc
     9421 tcggctgctt tcggcaagac ggttgtgttc gtcgatatcg tgtgcatccc acggatagtt
     9481 aatccaccag tcgtctacgg tgatgccgct gaaataggga atgccttcgg ggattttgcc
     9541 tgctttggct ttgatttttt cgtgcaggac ggcgacgccg atcgtaccga agtcttcctt
     9601 gagcagttct ttcaggcaga actccatggt tacgcggctg tcgtccactt cgtcgacgac
     9661 gagtacgttt ttgccccgca gggcttcggg aacggggtcg agccattgga cttttttgac
     9721 ttcttcggta acctgtcctt cgttgtcgct gtcgtaatag gcggtggtta cggcataaat
     9781 cggaatttcc agaaaacagc gcagcatacg tgccggaata aagccgccgc cgccgatggc
     9841 aatcatggca tcgtatttga tgtcggcgtt ccggattttt tctgccaatg ctttgatgac
     9901 gcggtggatg tcatcgtagg tgtaccagat tttctgtttc atcggaattt ccttggtggt
     9961 tggggctttt ggaatatttt cacgggttat tatacggaac gctttgcccc tgtgtgttga
    10021 cgtatggcga aagtttggac ggatggtgcg tccaatgcaa aaaaagccag taattgcatg
    10081 gcaatgttct ggctttttca gtcagtcgaa tagggattat tcgcctttgg ctttgaccac
    10141 tttgcggccg cggtacatac cgttggggga aatgtggtgc gggcggtgta cttcgccggt
    10201 tgtgctgtcg acagacagtg cgggcgcggt cagcgcgtcg tgcgaacggt gcataccgcg
    10261 tttggaaggg gattttttgt tttgttgaac ggccatttca agctcctgga taaataaact
    10321 gtgtcctaat caattgcttt tcaaacctgc caaaacggcg aaggggtttg gtttgtcccg
    10381 atcggctttt tccggtgtcc cgttgctgcc gcagtcttcg tgccggggag agaaggggag
    10441 cgacatcagg atttggtctt ctaccaatgt gcgcacgtcg agttcttttt caatcagtat
    10501 gccttcgagt tcttcgtcgg caagcatgga ttcgtccaag gactcttcgt tggaaaacag
    10561 gacgatacgg ctgctttcat caagcatgaa cggcatgggt ttgatacatc tctggcaaat
    10621 caggggcata tcggctttga cgttcaggtc gaggaacagg cgttgcagcc ggtcgcgacc
    10681 gccggtcagt gtaaacgata ttttggtctg cctgtcggcg ggataatcgt gcgaactgac
    10741 gcgttcatcc aattcttcca gcagaaaact gccttgcagg ttctgccctt cggcggcaaa
    10801 aatttccggg tcaatcaaat tagggtctga cataaacggg atatgatata atttagatgt
    10861 tctaacgtca atatttttaa gaaaaatgtt gcggtacgcc gaaggcgggt atccgtgttt
    10921 cggcgcatgg ctggatttta ctgccccttc gggcgtgttt tcaacggtaa ggaggatggg
    10981 atgggtttgg aactgccttt gattttgggt acgagttcgg ttttccgccg cgaacagatg
    11041 gaaaggctcg gcattgcctt tcaggcggcg tcccccgatt ttgacgaaac gccgatgttg
    11101 ggggaatctg cccctcagac ggcattgcgc cttgccgagg gtaaggcgag gtcgttggcc
    11161 ggacgtttcc ccgaggcgtt gattgtcggt gcggaccagg tggcgtggtg cgacggcagg
    11221 cagtggggca agccgatgaa ccttgccaac gcgcaaaaga tgctgatgca tttgagcggc
    11281 agggagattg agttttacag cgcggtcgtt ctgctaaata cggttacggg caggatgcag
    11341 cggcatatcg ataagacggt ggtcgtgatg aggaagttgg acgagctgca catcctccgc
    11401 tatttggagc gcgagcctga tgcggtttat tgctcgtgtg cgttgaagag cgaggctttg
    11461 ggtgcattgt tgatcgaacg gattgagagt accgatccga atgctttaat cggtttgccg
    11521 gttttccgtc tggtcgattt cttgaaaaat gagggcgtgg aggttctgta actgcccgtt
    11581 tatgccgtct gaaaggctca gacggcattt ttaaccgatg agtgagggaa tgatgtctcc
    11641 tgttttgtat ttgattccta cgcctttggg tacgcccgat acgccgtgcc tgttgccgca
    11701 tgaacaacag gcggttgtcg ggctgacgga ttttgtcgtg gaagcggaaa aaacggcgcg
    11761 cgcgcatttg aaacatttgg gcgtgacaat gcctatccgc gaactgaatt tgcaaacgct
    11821 gaacgaacac acggatttga agactttgcc ggaattgctg aaacctttgc aagaagggcg
    11881 cagtatgggc attgtcagcg aggcgggttg cccggccgtt gccgatccgg gtgcgaattt
    11941 ggtggcattg gcgcataaac acggttttga agtgcgtccg ctggtcgggc cttccagcct
    12001 gctgctggct ttgatggctt cgggtgcgaa cgggcagagt tttgcgttta agggttatct
    12061 gccgtctgaa aaaaatgagc gcattcagag tttgaaggct ttggaacaac gttcgcgcca
    12121 gcagaatgaa acgcagctgt ttatcgaaac gccgtatcgc aacgatgtgt tgttggcgga
    12181 tgcggtggaa aacctgcatc ctgaaacgcg cttgtgcacg gctacggatt tgacgttgcc
    12241 gactcagtcg gtggtcagta aaacggttgc ggattggcgc aggatgaagg aaatgcccaa
    12301 tctgaaaaaa cgcccgacga tttttgtgat gtatgcaggt tgaagatttc cgccccgata
    12361 gggggtgagc aataaaaatg ccgtctgaac aggtttcaga cggcattttt catgctgcgg
    12421 catttaggaa acgacttcgc cttgggcgcg ttgtttttcg atgctgcggt tgatgtgcca
    12481 ttgctgggcg atggtcagga ggttgttgac tacccagtac aataccagac cggcagggaa
    12541 gaagaagaac atgacggaga aaaccaacgg catgattttc atcattttcg cctgcatcgg
    12601 gtcggtcggc ggcgggttca gataagtttg ggcgaacatc gttgccgcca taatgatggg
    12661 caggatgtag taggggtcgg cgcggctgag gtcggtaatc caacccagcc aaggtgcctg
    12721 gcgcaattct acggaggcga acaatgccca atacaatccg atgaagacgg ggatttgcaa
    12781 cagcataggc aggcagccgc ccagcgggtt gattttctcg tctgtgtaaa gctgcatcat
    12841 cgcctgttgt tgcgccatac ggtcgtcgcc gtatttctct ttgatggctt gcagtttggg
    12901 cgcggcggca cgcattttcg ccatagagcg gtaagaggcg ttggtcaatg gatacagtac
    12961 ggctttgacg atgatggtta aaacgataat cgcccagccc cagttgccga tgatgttgtg
    13021 cagttggttc aggagccaga agagtgggga ggcgaaccag tgtactttgc cgtagtcttt
    13081 ggccagttgc aggttgtcgg cgatgtttgc gatgacggaa gtggtttgcg ggccggcata
    13141 caggttgacg gcggtttcgg ctttcgcgcc ggccgggatg gcggcaaggg gaacgctgac
    13201 gcttgcgctg tacagcttgt cgttgcggcg tttgatgtcg atgctgcagt cgccagcggc
    13261 gcaaacgctt tgtccgcctt tgggttgcaa aatccaagcg gacataaagt ggtgttcgat
    13321 cataccgagc cagccggtcg gggttttgcg gatgtattcg gcctcggatt tgccggattt
    13381 ggcatcgtcg tccaagtcgg agaagctgac tttttggaag ttgccttcag gggtataaac
    13441 aacagggccg acgtaagagt gggtaaagta accttgaccc tcgggttcgc tgtggtcgcg
    13501 gacgatgcgg tagtccgcgc tcaggttggc ggtttgaccg ctgccgttgg cgatgtcgaa
    13561 gcggacgttg accagatagc tgcctttggt gaaagtataa actttgtcga ttttcagacc
    13621 gcgtgtttca ggtgcgctca ggcggacttc aactttgtcg ccttccaagc tgtactgttt
    13681 tttcggtgcg ctaaagccga tgccttttag aatgttgttg ccctgcgcgt ccaaaagttc
    13741 ggattgggcg acgtaggtgt attctttgcc gtcgccaaac aggatgaacg gtttattttc
    13801 gtcgccggtt gctttgtatt tgagcagggt cagccggcgc aggtcgccgc ttttttcatc
    13861 aatgacggct tgaaccgtgt cggtcgttac ggtaatcggc gttgcgggcg cgagcgcggc
    13921 ttcggcggaa gcggttacgg cctgttgttg tgccgtctgt tggggcgcgg ggacgggctt
    13981 cggagtgggg aacatctttt cccatccgat cataatcacc agtgcgatgg cgaaaaacgc
    14041 cgtgagtctt ttaaaatcca taagagtttc ctgaatggtc ggaaatgccg caggttgcgt
    14101 gttccgatag acggggaata agggcgggct tcatacccga cggtcgtgcc gccagcccga
    14161 aggttcagac ggcattatat agaaaccgat gggaaataaa aggaaagcgt gcaatttgaa
    14221 tattgcgtcg ggtcagggaa cggggtcgtg tccgtgtccg ccgaaagggt ggcagcgtgc
    14281 aatgcgcttg atggcgagcc ggccgccttt gaatgcgccg tattttttga ccgcttcgac
    14341 cgcgtattgc gaacaggtcg gcgtatagcg gcagcgcggc ggaatcagcg ggctgatgca
    14401 atattggtag aaccgtatca gtcccagcag gagtttggac aataggaagt tcatcgggat
    14461 gttccttagt atgggaaacc cgttgccgtc tgaaccttgc ctgcagagta ccgttctgat
    14521 catgcctgtt tcctgcatcc ggttgcgggg ttgccgaaca tgagttgtgc cagttccacc
    14581 cttgcctgtt ttgcggtagc cctgtcgaat ttacggcgga cgcgcacgac gaaatcttgc
    14641 ggcggcagcc ggtttttgtt caatctgaac cagtcgcgga taacgcgctt catataattt
    14701 cgttcgttgg cgcgtttggc ggtttttttg ccgaccacca gaccgatgcg gggatggtcc
    14761 agcccgttgc cgtttgaacg cgaaacttgc agcaggtcgc ggctgcggcg gtttctgaat
    14821 gcaaaaacgg atgaaaaatc atccgttttt aacaagcggt actgccttcc gaagcggtag
    14881 tccaaaatta taccgccagg cgtttgcggc ctttggcacg gcgtgcggcc aatactgcgc
    14941 ggccgccgcg tgttttggag cgcaccagga agccgtgggt gcgtttgcgt ttggtaacgg
    15001 aaggttgata agtgcgtttc atgatgtttc ctaaaaatcg gtagatagat aaaccgtgaa
    15061 ttacactcca atttgccgct tttgtcaatc aatatagaaa ctttgcagga agattgcccg
    15121 attgcctgcg gatttccgcc gcctttctgt ggataaattt ttgcacgggt tgtggataaa
    15181 atattcgtga gtcggtataa tcgggcagtc gcgttttgaa ccgatgtgcg ttcaacagat
    15241 ttgttttctt tttgaaaata ttatattttc tttgttttcg atttcatttt taccgattcg
    15301 agcctatcca tgacattagc agagttttgg ccgctgtgcc tccgccgtct tcacgatatg
    15361 ttgcctcaag ggcagtttgc gcaatggatt gcgcccctta ccgtcggtga ggagggtggc
    15421 gtatgggtgg tgtacggcaa gaaccagttt gcctgcaata tgctcaagag ccagtttgcc
    15481 ggaaaaatag aagcggtgag ggaagagttg gctgccggcc gttccgcctt cgtattcaaa
    15541 ccgggagaag gcgtgcgtta tgagatggcg gcggttgaag gtgctgtcga acctgccgag
    15601 ccgtccttgc acgcggtgtc ggaggaaatg cccgtgcagg aggttctgtt ggacgagctg
    15661 ccgtctgaag agcctgccaa atccgtacag gcgaaaacgg cggcggatat tttggcggaa
    15721 cgtatgaaaa acctcccgca tgagccgcgc catactgccg ggtctgcttc ccgtccggaa
    15781 tcggaggtac ttgcgaaagc gcggacggat gcgcagcgtg atgcggaaga ggcgcgttac
    15841 gaacaaacca acctgtctcc ggattacaca tttgatacgt tggtagaagg caagggcaac
    15901 cgccttgcgg cggctgcggc gcaggcgatt gcggaaagcc cggggcagag ttacaacccg
    15961 ttcttcctct atggcagtac gggtttgggc aaaacccacc ttgtgcaggc ggtcggcaac
    16021 gagctgctga aaaaccgtcc cgatgccaaa gtgcgctata tgcattcgga tgactatatc
    16081 cgcagcttta tgaaggcggt tcgcaacaac acttacgacg tgttcaagca gcaatacaag
    16141 caatacgacc tgctgattat cgacgacatc cagttcatca aaggcaaaga ccgtacgatg
    16201 gaagagtttt tctatctgta caaccatttc cacaacgaga aaaaacagct catcctcact
    16261 tgcgatgttt tacccgccaa aatcgaaggt atggacgacc gcctcaaatc ccgtttttca
    16321 tggggactga ctttggaact cgagccgccc gaattggaaa tgcgcatcgc cattttgcag
    16381 aaaaaggcgg aagcggcggg catcagtatc gaagacgaag ccgcgctgtt cattgccaat
    16441 ctgatccgtt ccaacgtgcg cgagcttgaa ggcgcgttta atcgtgtcgg agcgagcagc
    16501 cgctttatga accgtcccgt catcgacatc gatttggcgc gtaccgcttt gcaggacatt
    16561 attgccgaga agcacaaagt catcaccgcc gacatcatca tcgatgcggt ggcgaaatat
    16621 taccgcatca aaatcagcga tgtgctcggt aagaaacgga cacgaaacat tgcccgtccg
    16681 cgccaggtgg cgatgagcct gaccaaagaa ctgaccactt tgagcctgcc gtctatcggc
    16741 gattcgtttg gtgggcgcga ccatacgacc gttatgcacg gcatcagggc agtggcgaaa
    16801 ctgcgcgaag aagatccgga attggctcag gattatgaaa agctgctgat tctgattcaa
    16861 aactgatgga aaacgttttc agacgacatg atattgccca tgccgtccga agggtaaaga
    16921 tatagcggat taactttaaa ccagtacggc gttgcctcgc cttagctcaa agagaacgat
    16981 tctctaaggt gctgaagcac caagtgaatc ggttccgtac tatttgtacc gtctgcggct
    17041 tcgtcgcctt gtcctgattt aaatttaatc cactatacaa accgatttaa aggagcgaac
    17101 atgttgattt tacaagccga gcgcgacagc ctgctcaagc cgttgcaagc cgttaccggc
    17161 attgtcgaac gccgccacac cctgcccatc ctgtccaacg tcctgattga gggaaaaggc
    17221 ggtcagacca aactcttggc aaccgatttg gaaatccaaa tcgacactgc gggtcccgag
    17281 ggcggcgcgg gcgacttccg catcaccacc aatgccaaga aatttcagga cattttgcgc
    17341 gcgctgcctg ccggtgcgct ggtgtcgctg gattgggacg acagccgtct gacgctgaag
    17401 gcgggcaaat cgcgttttgc cctgcagacc ctgcctgccg ccgattttcc gatgatgaat
    17461 gtcggcgagg acatcagcgc gactttctcg ctggagcagg agcgtttcaa aaccatgctg
    17521 tcgcaagtgc agtacagcat ggcggtgcag gacatccgct attatctcaa cggtctgctg
    17581 atgcaggttg agggcagcca gttgcgcctt gtggcgaccg acggacaccg ccttgcctat
    17641 gcagcctgcg cgattgatgc ggatttgccg cgcgccgaag tgattttgcc gcgcaaaacg
    17701 gtgctggaac tgttcaaact gttgaacaac cccgacgatc cgattcaaat cgagctgctg
    17761 gacaaacagg tgcgtttcca atgcaacggc acgaccatcg tcagcaaggt catcgacggc
    17821 aaattccccg atttcaaccg cgtgattcct ttggacaacg acaagatttt cgtgttgtcg
    17881 agggcagaat tgttgggcgc gttggaacgt gcatcgattc ttgccaatga aaaattccgc
    17941 ggtgcgcgat tgtttttgca acccggcctg ttgagcgttg tgtgcagcaa caacgagcag
    18001 gaagaagcgc gcgaagaaat cgaaatcgcc tatcagggcg gcgaactcga agtcggtttc
    18061 aatatcggct atctgatgga cgtgttgcgc aacatccatt ccgacgatat gcagcttgcc
    18121 ttcggcgatg ccaaccgctc gacgctgttt accgtgccga acaatccgaa tttcaaatat
    18181 attgtgatgc cgatgcggat ttgacggttt tccggaacac gatgcccgta ttggagatat
    18241 accccgaacc gtgcagacgg attcggggtt ttgttcggct gtcggaaagg taatgccgtc
    18301 tggaatgcgg cggattgggg ttgggagcgt ataggggaag tgcttgtgca ggaatggcga
    18361 aggtgtgttt ttgactccgg tccgccctgt ttagattgct gtaaaaccat gccgtctgaa
    18421 acggaaaggt ttcagacggc atggtttttg attggggcgg tgcgggtcag cctccgagca
    18481 gtgtccacaa atcgttttgc aggtcggctt cggattcgcc ctcggcgggc gcggcgcgga
    18541 tatagccgcc gtcgggctgc atcagccacg cgtgcgtatt gtctgccaat gccatttcca
    18601 aaccttcgcg gatgacgcgt tttttgagtt cgggcgcggt aatcggcgcg gcggtttcga
    18661 tgcggcggaa gaagttgcgc cccatccaat ccgcgctgga gataaaggta tcgtccgcgc
    18721 cgttgttgtg gaagcaatac acgcgcgcgt gttcgagctg cctgccgatg atggagcgga
    18781 cgcggatgtt ttcggacaag ccttttacac ccgggcgcaa ggtgcacata ccgcgcacaa
    18841 tcaaatcgat ttgcacgcct gccgcgcttg cccgatacag ggcttcgatg acggtcggtt
    18901 cgatgagcga attcatcttg gcggtgattc gggcgggttt gccggctttg gcgtgttcgg
    18961 tttcgcgtgc gatgcggtcg ataaccattt tgtgcagggt aaacgggctt tggtagagtt
    19021 tgttcagccg cccgggtttg cccaagcctg tgatttccat aaacaatgtg ttcacatcgg
    19081 cggtgatttg ttcgtcggcg gtaatgatgc cgaagtcggt gtagatgcgc gatgtgcctt
    19141 ggtggtagtt acccgtgccg aggtgggcgt aacgcttgag tacgccgtct tcgcggcgga
    19201 tgatgagtgc cattttggcg tgtactttgt agccgaacac gccgtatacg acgtgcgcgc
    19261 ccgcctcttc gagctgcttc gcccagttga cgttgttggc ttcgtcaaaa cgcgccatca
    19321 gttcgacgac gacggttact tgtttgccgg cgagtgccgc cttcatcagg gcgcggacga
    19381 gttcggagcg cgtgccggtg cggtaaatcg tcattttgac ggcaagcacg tcggggtcgg
    19441 cggcagcttc gcgcatcatt tcgacaacgg ggtcgaacga ttggtagggg tggtgcagca
    19501 ggatgggcga ttggcgcacc aaatcgaata tggacgcggt tttgcccaag gctttcagtc
    19561 tgcccggcgt gtgtgtggga aatttcaaat cggggcggtt gactaggtcg gggacggcgt
    19621 tgaggcgcac gaggttgacc gggcctttga cctgatagag ttcggcggcg gtcagtttga
    19681 attgcgcgag cagaaagtcg cggatgtagg cgggacaggt gtcggcgact tcgagccgca
    19741 cgccgtcgcc gtattcgcgg tcgtgcagtt cgttttgaat ggcggcgcgg aggttttgca
    19801 ggtcttcttc gtcaacggtc aagtcgctgt cgcgcgtcag gcggaactgg tggcagcctt
    19861 tgacgttcat gcccgggaag agtttgccga cgtgggcgtg caggatggag gagaggaaga
    19921 cgaagccgtg tccgccgcca cacagttcgg acggcagggg aacaacgcgc ggcaggatgc
    19981 gcggtgcctg cacaatcgcc atccccgaag gcctgccgaa cgcgtccgtg ccgtcgagtt
    20041 cgacggcgaa gttgagcgat ttgttcagcg gtcgcgggaa ggggtgggac gggtcgagtc
    20101 cgatgggggt caggatcggc agcagttcgc ggtcgaaata gtcttcgatc cattttttct
    20161 gcgcgcccgt ccagttgcgg cggcggtaaa aatggatgct ttcccgcgcc aactcgggct
    20221 gaaggacgtt gttgaacagg tcgtactggt gccgtatcag ggagcgcgcc gcttcggtaa
    20281 cgtcggcgat ggtttcagac ggcattttgc cgttgtccag cctgcgccgg gggtgcagct
    20341 tgttttcacg cttgagccac gccatgcgga cttcgaaaaa ctcgtcaaga ttggacgaca
    20401 cgatgcacag gaagcgcagg cgttccaaaa gggggacgtt tttgtcttcc gcctgtgcca
    20461 acacgcggcg gttgaatgcc agcaggctta gttcgcggca gaggatgcgg ttttgttcgg
    20521 gcataaggtt ctcccaaaga tggttgttgt tcggtcggag cgggcaggca atgccgtctg
    20581 aaggcttggc ggcatctgcg ccggtttcag acggcatgac gtggcggaca gcctgtttca
    20641 ggcatcgggg caatgtgaaa acagataccg gcgcgtgcgg tatccgtctg tttcaaatca
    20701 cttccaacac aaaataatga cgcagttttt cgtacaccgc atcgctgacg ttgatgcagc
    20761 cgttggtcat aatcctgtcg gacacggacg gggaggcgat gcgttcgttc cgcctttccg
    20821 acggtatctg attccaaacg cggtgcaggg cgaaaagaaa atcaccctcc tgcttgaaac
    20881 cgatgacttc gccgccgtat ccaggcttgt cggtactgtt cagcgtcagc ccgaacgtcc
    20941 ccttgggcgt ggcaacaccg atgaggacgg ggtggcactg acggtcgtca gcgaaacaga
    21001 gttccgcttt ggatgtatcg acgatgactt ttttcttttg gatataggca ttgatcgcat
    21061 ccggttgccc ctgtgcatat acgggggcaa ccattgacag gccgcataat atccctaaaa
    21121 acaggcggaa cggcatgtcg gattattggc ggatacgttt cggttttgcc ggcacgattt
    21181 cgcggatgat gacttgcggc tcggctttgg gtgcgggcgg cggacaggcg gcatctttcg
    21241 ggaagacggg gttccagtag aagctgcggg caaatttgtc tttatcgaaa atcactttgt
    21301 attggcaggt agtaacatct tctacgccgg aagtgttttc agggtcgata cctacgcccg
    21361 gggtatggaa gtggaacagg taatcccatt cgcgcacgcc gtacatacct tcgtcgtaat
    21421 gcgggcggcc caggattttg tagatgtcgt ctttggtcag gccggggcgc atctgatcca
    21481 gttcgtcata agtcgggaat gtgccgcgct tgttgtcgag cgttacggaa tagggtttcg
    21541 ggaaaaccgg attgtcggtc gtgccgtcgg ctttgacgtt gcttttggtt gcgcaggcag
    21601 acagaacgcc cgccgccaat actgccaagc ccggtttgac gatttgtttg attttcatat
    21661 gcagaatcct cttttacccg atgcccgtct gccttttgtt cggaagagcc gcatcaggag
    21721 agttttaaac atttgatttt ggtttgtaat attagcataa aaaacgtgcg tatcaataaa
    21781 cgcggtgtat ttgtacggca tacggaataa tgcgcgtgcg aatttacgca tcctgccggc
    21841 aatctgccga ttcgccgctt ccggcaacct gttataattg atgccgactt tatttttcca
    21901 acgtttttaa gcgaaaacag aatgactatg caagaacaat atcaacccgc cgccattgag
    21961 cctgcggcgc agaaaaaatg ggacgacgag cgtattttca acgtctccga agacgcttcc
    22021 aaacccaaat attattgcct ttccatgttc ccctatccca gcggcaagct gcacatgggg
    22081 catgtgcgca actacaccat cggcgacgta ttgagccgct tcaaacgctt aaacggcttc
    22141 aacgtcatgc agcctatggg ttgggacgcg ttcggtatgc cggcggaaaa cgcggcgatg
    22201 aaaaacaacg tcgcccctgc cgcatggact tacgacaaca tcgaatacat gaaaacccag
    22261 ctcaaaagcc tgggttttgc gattgactgg gcgcgcgaaa ccgcaacctg caaacccgaa
    22321 tactaccgct gggaacaatg gctgtttacc aagctgtttg aaaaaggcat cgtctatcgc
    22381 aaaaacggca cggtaaactg ggacccggtc gaccaaaccg tattggccaa cgagcaagtc
    22441 atcgacgggc gcggctggcg ttcgggtgcg ttgatcgaaa aacgcgaaat cccgatgtat
    22501 tacttcaaaa tcacggatta cgccgaagag ctgctcaatg atttggacaa gctggaacac
    22561 tggccggaac aagtcaaaac catgcagcgc aactggatcg gcaaatctcg cggcatgacc
    22621 gtgcgcttcg ccgtttcaga cgacagcaag caaggcttgg aaggcgatta cgcgaaattc
    22681 ctgcaagttt ataccacccg ccccgacacg ctgatgggcg cgacttatgt tgccgttgcc
    22741 gccgagcatc cactggcaac cgccgcagct gccgacaaac ctgaattgca agagtttatc
    22801 gccgaatgca aagccggctc ggttgccgaa gccgatatgg cgacgatgga gaaaaaaggc
    22861 gtgccgaccg gccgctacgt cgtcaacccg cttaacggcg acaagctgga agtgtggatt
    22921 gccaactatg tattgtgggg ctacggcgac ggcgcagtga tggcggttcc ggcgcacgac
    22981 gaacgtgatt tcgagttcgc caccaaatac aatctaccta aaaaacaagt cattgccatc
    23041 ggcgacaaca catttgacgc caaccaatgg caagaatggt acggcgacaa agaaaatggc
    23101 gtattggtca acagcggcga cttggacggc atgaattttc agacggcctt cgatgccatc
    23161 gccgccaagc tgcaaagcca aagagcgggc gaaccgaaaa cccaataccg cctgcgcgac
    23221 tggggcattt cgcgccaacg ctactggggc tgcccgattc ccatcgtcca ttgcgaaaaa
    23281 tgcggcgacg tacccgtccc tgccgaccaa ctgcccgtcg tcctgcctga aaacgtcgta
    23341 cccgacggca tgggttcgcc tttggcaaaa atgcccgagt tttacgaaac cgcctgccca
    23401 tcatgcggcg gcgcggcgaa acgcgaaacc gacaccatgg acaccttcat ggaatcgagc
    23461 tggtatttct tccgctatat gtcgcccaag ttttcagacg gcatggtatc ggcagaagcc
    23521 gcgaaatact ggggcgcggt cgaccaatac atcggcggta tcgaacacgc gattctgcac
    23581 ctcttgtacg cgcgtttctt caccaaactg atgcgcgacg aaggcttggt cagcgtggac
    23641 gaaccgttcg aacgcctgct gacgcaaggc atggttgtct gcgaaaccta ctaccgcgaa
    23701 aacgacaaag gcggcaaaga ttggatcaac cccgccgatg tcgagctgac gttcgacgac
    23761 aaaggccgcc ctgttttcgc cgtcctcaaa gccgacggac tgcccgtcgt catcagcggc
    23821 acggaaaaaa tgtccaaatc caaaaacaac ggcgtcgatc cgcaagagct gattaacgcc
    23881 tacggcgcgg acaccgcccg tctgttcatg atgttcgccg caccgcccga acagtccctc
    23941 gaatggagcg acagcggcgt cgaaggcgcg caccgcttcc tgcgccgcct gtggcgaacc
    24001 gtttacgaat acctgaaaca aggcgaagcg gtcaaagcgt tcgcaggcag ccaagacggt
    24061 ttgtctaaag aactcaaaga cctgcgccac aaactgcatt ccactatcgc caaagtcagc
    24121 gacgactacg gccgccgtca gcagttcaac accgccatcg ccgccgtgat ggaactgctc
    24181 aaccaatacg acaaaaccga caccggcagc gaacaaggcc gcgccgtcgc ccaagaagta
    24241 ttggaaaccg ccgtacgcct gttgtggccc atcgtgccgc acatctgcga aaccctgtgg
    24301 agcgaattga acggcgcaaa actgtgggaa gcaggctggc cgacagtcga tgaagcagcc
    24361 ttggtcaaat ccgaaatcga agtgatggtt caagtcaacg gcaaactgcg cggcaaaatc
    24421 accgttgccg ccgacgcatc caaagccgac ctcgaagccg ccgcactcgc caccgaaggc
    24481 gcggtgaaat ttatggaagg caaaccggcg aagaaaatca tcgtcgttcc cggacgcttg
    24541 gtgaatatcg tcgtctaaac cgcttttaag gtttagccat acggataaag gccgtctgaa
    24601 acttggaaac agggtttcag acggcctttt taaggcagat tgggttgtct gcatgacaaa
    24661 ccccgaataa ctgaaatctc aaaatccaaa acatgaattt atttttcgat accgaattgg
    24721 gaaagcaaca aaataaagca acccacaaaa tccgtgtaat gagcgaggct tggctggaaa
    24781 aaaacggcta ctgcccctgt tgcggaagca agccgatgca gagatttgcc aataacaaac
    24841 ctgttgcaga cctcttttgc ccaaattgcc acgagcaata tgaattaaag agtaaaaatc
    24901 aaaaaaccat aggcaacagc gtgcctgacg gtgcatatca caccatgttg gagcgcatcc
    24961 ggtcagatac caaccccaac tttttctttc ttgcatataa aaaagcggat tactccatac
    25021 ggcaattggt gcttgtaccc aaacatttca tcacgccgga tatgattatt cccagaaata
    25081 aaggcattaa aaaccggccg caccacatta tgtgttccat caatctcgcc cctttgcctg
    25141 aaagcggaaa aatattctta atagacgatt cccgcattat cgaacccgaa accgttctga
    25201 aaaaatggca atccaacctg tttttacgca accaaaatgc ggagcgtaaa ggctggcttt
    25261 tggctgttat gaaatgtatc gaccaactcc ccgaagaatt cacattgtcg caaatgtatg
    25321 gatttgaaga caaactatcc atccaatttc cccaaaacaa ccatatcaga gacaaaatcc
    25381 gccaacagtt gcaaattttg cgcgaccaaa atacgatcga attcattggt cgcggacttt
    25441 acaaaaaaat cgacaaattg cgtccgactc ccaaggcgtt ttaatttcaa atcatgatac
    25501 tgaatttacg agagatattt attcttctgc cattttgaaa acagttgaag ttcagcgcaa
    25561 tattgccgca aaaggcagca gccgtaaaaa agtcggggaa ttattggcaa tttatgcgtg
    25621 atttcgacaa accggctgaa gaagctgcta tttatcaaag tcgtttgaaa aaaaatcgtt
    25681 tcagacgacc ttgtcctcta caacgaaaat tcccttaacg tcatgcggaa gatattggaa
    25741 aaacatccaa acagctgttt tgatatgatt ttcgcagacc ctccttactt tctttccaat
    25801 gacggcttca gttgtcaaaa cggacaaatg gtttccgtca ataagggcaa ctgggataaa
    25861 tccaaaggaa tggcggcaga tttggaattc tacgaagaat ggctccgact gtgttacgcc
    25921 ttattaaaac caaacggcac aatttgggtt tgcggcacat tccataatat ttatttaatc
    25981 ggctacctga tgcaaactat cggataccat attttgaaca atattacttg ggaaaaaccc
    26041 aatcctcccc ctaatttgtc ctgccgtttt tttacccatt cgacagaaac aatcttatgg
    26101 gcaaagaaaa ataaaaaagc caaacacacg tttcattatg aaatgatgaa agcacaaact
    26161 gatggcaaac agatgaaatg tgtttggaca tttcctcctc caaacaaagc cgaaaaaaca
    26221 ttcggcaaac atccgacaca aaaaccactc cccttgcttg aacgctgcat actctcagct
    26281 tcaaacatcg gagatttaat ttttgaccct ttcatgggca gcggcacaac aggcgttgcc
    26341 gccttaaaac atggtcggaa attttgtggt tgcgaactgg aagaagattt ttttgaatta
    26401 gcaaaaaaaa ggttagaaaa atgattattg gcggaatcgg tggtgcaagg acacaaacag
    26461 gactcagatt cgaagaacgt acagacttac gaaagttgtt tgaagaaatt cccgggtacg
    26521 acttaagaaa aacatatgat aatgcgggtt atgaagtttg gttcaatgga gaattgaagg
    26581 cttattgttt taaaaaatat gagttttacc gatttttgaa aagaccggga tacagtatta
    26641 attggaaaga ccatctgtct aaaagattac tacccgacaa tggcttattt atcatcatcc
    26701 gtgatacctt atttattatt gagatcaaat tccaacaaac tcccggttca gtagatgaga
    26761 aattacaaat ttgcgatttt aagagaaaac aatatacaaa attggttcac tctttaggtt
    26821 ggcgggttga atatgtctat gttttgaatg attggtttac aaagccggaa tataaagatg
    26881 ttttagatta tattatcagt gttaactgcc attaccaatt taacacgatt cccttaaggt
    26941 ggtttggact gcctgatggt gaaacaaatg aataaatacc atatttaaaa cacagccgtt
    27001 caaggtcgtc tgaatatcat ttcagacgac ctttcaccaa tccccgccgt tttccatctt
    27061 tctgctattg tgataaagta gcccgacctt ttgttcaaaa tacgcggatt ccgcgacact
    27121 gaatgcagca tctgtcaaag attatttgaa aacggtcgag ttagacaagt ctgccgacaa
    27181 tgtcgatacc acatccaaaa ctatccgcag ggtttaggcg gtattccaga gtacggtgtc
    27241 ttatgctgat gctgtaaaca atgcccgtat agaaaatcta aaacggttgt tgccgaccgt
    27301 tatgccggtt tatgagcaaa gtgtcagaaa taaggggcgc gttaataaaa aacgtcggcg
    27361 ttaagggaag gggatcgaga atttgagccg ttgtttcaaa atgccgtctg aaatcgtttg
    27421 agattcagac ggcattgaaa cagttctgag ccccgcccgt tttgccttca agcccgcgcc
    27481 gcttaaatcc aatcccccct gcaacgggcg caaaaaaatc cccgtgcctt gcgaccgggg
    27541 atgtttcggg tttcgcgccc gtctgcgccg tgccttgctg tcgggctatg tcgtctgcac
    27601 cgccgccgtt tcggcttggt ttgatgcggt cgggcattta tgcggctatg ccctgatatt
    27661 cggttcggcg gtcttgcctg tcttggcagg catattcagc agcgcgtcta ttgtgaactt
    27721 gctgattttg ccgtttgcca agtcggctac gcaatggctt cgataccctt gtttttgacg
    27781 atggtcagca gcttcaacgc cgcgccgctc ggctttttaa cgccccgctc ccaagccgaa
    27841 acgtgatttt ttcccacgtt gagatagatg gcgaaagcgg cttgcgatag tgcctccttc
    27901 tccctgattg ccttgatgtc tccgccgctc aacggtttga tttcggtcag gcaggacttg
    27961 tcaaagccgc gcatagtctt tttgtcgatt gcgccgatgt tgtaagcccc ttccatcatt
    28021 tcatgaatgg cggctaatgc ctcgcttttg tatttcatga ttctatctcc gtgataatgc
    28081 cgtcttcttt caaagccgcc agctctgccc gcgtgtattt cagataatat gcggcggctt
    28141 ttcggtaaac gtccagttct ttatccgaaa tgttttccct gtcgttcttg gcaaaggcgt
    28201 aaacgaaaat gccctatctg cctgtttgaa caatatcagg ctgcgatagc cgccgcttct
    28261 gccttgtcct tgccttgcta tgcgctgctt aatcacaccg ccgcctaaat ctgcgtctat
    28321 cagcccgtta tccgcccgct ctaccgcttc cagcagctcg gaatcgttga ttttgtgctt
    28381 cttggcaaat ttcactatcc attggttttt gaatatccgc attgtgtagc cgttgattag
    28441 tgatacttgg aattatacca gagacagaca acacggcaag ctgccttttt tatgccccgc
    28501 aatttctccg tttatgccgc ctgaaacact ggcggctaac ctgattattt tttaatcaat
    28561 cgcttttaat ggctcaaatt gcgtttttag cgcgtttcgc tgtcttccta tgcccccata
    28621 tataaccaag tggtttaacc gccattcctg ctcaaaatag gcgcggttcc gtgcgttttg
    28681 gcttttcatt ccgctacgct cccactgcca agacggtgaa aaaccggaaa accccaaaag
    28741 ttgttaccga ttcgttacca tttgttaccg catttgttac caatttttta tctttttctt
    28801 attttatagt gaattaaatt taaaccggta cggcaaggcg aggcaacgcc gtaccagttt
    28861 aaatttaatc cactatagta taggtttttt ccaaaaaccc aaaaaaaacc gctctgcatc
    28921 ttggacggtt tccccctcat tccctacggt gcgtcagtat tccccgcaag ctatttcccg
    28981 cttggcattc ctgatttggt ggtcgttcag ctttattttc acgtattttt cgcggtattt
    29041 tcggatgccg taaaaaatca ggttagttca attagggcgg attggacggg attgtacggt
    29101 caggaagggg gacggcagga taacaatcag cctgaaatcc ttgtattgat tgggattggt
    29161 tgacggcatt agacaggatt aaacgaaaaa aaacgcttag aatttctaag cgttttgtgt
    29221 gttggtgccg acagcgagat ttgaactcgc acagcctacg gccactaccc cctcaagata
    29281 gcgtgtctac caatttcacc atgtcggcat ttgaaaaact gttatttctg ctgctgagga
    29341 acaggggcag aaggttcggt attgcttacg ggtttgggtg cttgctgagt ttgttgtacg
    29401 ttgctgaagt ccaaaccgtg ttttgtcgtg tgggtgtgaa tatacaccat agccatgcag
    29461 gttgcaaaga aaaatgttgc tgcaacggcg gtcgaacggc tgaggaagtt agcgttgccg
    29521 gcagagccga atacgccttg cgcgctgccg cttcccgatc cgaaggtcgc gccggcatcc
    29581 gcgcctttgc cgtgttggag caatactaac acgatgacgg ccaaagcgga aattatatta
    29641 acaatccaaa ttagggtttt gaaggcttcc atatttttct acgcattttg tgcggcactg
    29701 atgatggcgg taaaggagtc gtacgacaat gacgcgccgc cgacgagtgc gccgtccaca
    29761 taaggtactg cgaagatgtc ggccgcgttg tccgctttca cacttccgcc gtaaaggacg
    29821 cggattttaa catcgcttcc gcacaaagac aagatttctt tgtagatgaa tgcgtgcata
    29881 tcggcaatct gttcgacggt ggcgactttg ccggtgccga tcgcccagac gggttcgtag
    29941 gcgacggcga tgtttttggt atccagccct tgcaggatgg aaagctgatg ggcgatgact
    30001 tcgtgttctt tgccggcttc gcgctcttcg aggctttcgc cgacgcacaa taacgggatg
    30061 agtccgacgt tgaggacgtt ttccattttg cggcgttgga tttcgttttt ttcgccgaaa
    30121 taaaggctgc gttcggagtg tccgatgagg acgatgtctg tgccggtgtc ggcgagcatt
    30181 tcggcggaca cttcgccggt gtacgcgccg ttgttgggga agcggctcac gtcttgggcg
    30241 caggtgagga tgcggttgtt taagacgatt tgcatggcgt tgtgcagttg cagcaggtaa
    30301 acggtcgggg cggcgagtcc gatgaggacg cgttcggcgg tggggaggat gcggaagcgg
    30361 tgcatgagcg aattgttgtt ctggagccgg ccgttcattt tccagttgcc gatgacccat
    30421 ttttgatccc acattccgat ttggtgatac atcttttttg ctccgtgtcg tgttttttct
    30481 gtctgccgcg tgtggcgcgt tgcaatgtga agtttagtgg atatgcggcg ggttcgcaac
    30541 ttggggcggg cggctgcggg ggtggtttgg aatgttgttt cgggcaggtt gttttataat
    30601 ggccgcctga tatgtatgca actataggag atgtgatgca cgcgcttcat ttttcggctt
    30661 cggacaaggc cgcgctttat cgggaggtgt tgccgcagat tgagtctgtg gtggcggacg
    30721 aggcggattg ggtggcgaat ttggcgaaca cggcggcggt tttgaaggag gcgttcggtt
    30781 ggttttgggt gggtttttat ttggtcgata cgcgttcgga cgaattggtt ttggcaccgt
    30841 ttcaggggcc tttggcgtgt acgcggattc cgttcggtcg cggggtgtgc ggtcaggctt
    30901 gggcgaaggg cgggacggtg gtcgtcgggg atgtggacgc gcatcccgac catattgcct
    30961 gttcgtcttt gtcacgttcg gagattgtcg tgccgctgtt ttcagacggc cgctgtatcg
    31021 gcgtgttgga cgcggacagc gaacatttgg cgcagtttga tgagacagat gccttgtatt
    31081 tgggcgaact ggcgaagatt ttggagaagc ggtttgaggc ttcgcgtcag gcggcttgag
    31141 actgacaaaa cgggctgtcg gtgcgtgccg aagttggcgc ggcgtgagtg tggttttata
    31201 atgcctgcta ttgttgaaac aattatttga cggagcacta aatggatttt gaaaaagcgc
    31261 ggttcaatat ggtcgaacag caaatccgtc cttgggatgt attggatttt gatgttttgg
    31321 acgctttgga ggagattccg cgcgagcgtt tcgtggatgc gtctttgcag ggtttggcgt
    31381 atgcggatac ggagctgccg cttgccaacg ggcataagat gctcgagccg aaagtcgtgg
    31441 cgcggttggc gcaaggcttg aagctgacga aaaacgatac ggttttggaa atcggcacgg
    31501 gatcgggcta tgctgccgcg ctgttggcga agctggcggg cagggtggtg tcggacgata
    31561 tcgatgcgga acagcaaaac cgcgccaaag cggtgttgga cggtttgggt ttggacaata
    31621 tcgattatgt gcaaaacaac gggctgaccg aactttccgc aggtgcgccg tttgatgcgg
    31681 tttatgtcgg cggtgcggtc aatattgtgc ctgatgtgtt gaaagaacag ttgaaagatg
    31741 gcggacgcat ggtggttatc gtaggccgca agcctgttca gcgcgcgctt ttgattacgc
    31801 gcaagggcga tgtgtttgaa gagaaggtgc tgttcgatac cttggtggcg catttggatg
    31861 ataaggatgc cgatccgttt ggcggtttcg atttttaaga tgttgacagg tcatgccgtc
    31921 tgaaagcgga tttggggctt cagacggcat tttgcttggt tttttgggat ttttgcgatg
    31981 gatatcgtgc aacttgggtc ggcggaattg aaggcgtgga tggacgaagg gcggatgttt
    32041 tgtttgttgg acgtgcgtac ggatgaggaa acggcggttt gttcgctgcc aaatgcgctg
    32101 catatcccga tgaatctgat tccgctgcgg caaaacgagc tgccggatga tgtgccgctt
    32161 gtggtgtatt gccatcacgg tatccgcagc ctgcatacgg cgatgtatct ggcggacgcg
    32221 gggtttgaaa acctgtacaa ccttcagggc ggcatcgatg catgggcggc cgagattgac
    32281 ggcaacatga tgcgttattg aggcaggcat ttcagacggc attccttaaa tgcgtgtacc
    32341 tgtggtgttc caaaaggtcg tctgaaagtg cagcttctgc gaagctaaag cgcggtatca
    32401 acgaagttaa aatttgcctg aaccttaaag gcagcctgca ccccaatccc ctctccccgt
    32461 gggagagggc taggacgagg ctggcaaact gaaagtttgc ttgggcggca ttttcaatgt
    32521 gcaggctg
//
LOCUS       DAXIDM010000010        31246 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000010 DAXIDM010000000
VERSION     DAXIDM010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 31246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31246
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.010"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(27..653)
                     /locus_tag="ACFOAE_000390"
     CDS             complement(27..653)
                     /locus_tag="ACFOAE_000390"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004640 - phosphoribosylanthranilate
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HFC6883950.1"
                     /translation="MKKIRTKICGITTPEDASVAAAAGADAVGLVFFQGSSRAVDIAR
                     AKKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFDRPYIK
                     AIRVQTASDIRNAAHCFPNAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGG
                     LTPENVGEAVRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR"
     gene            complement(712..1203)
                     /gene="greB"
                     /locus_tag="ACFOAE_000391"
     CDS             complement(712..1203)
                     /gene="greB"
                     /locus_tag="ACFOAE_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HFC6883951.1"
                     /translation="MSTETKNYITPARWQALKDELYQLVNKERPEIVQIVNWAAGNGD
                     RSENGDYLYGKRRMREIDRRIRFLTKRLEAAVVVDPELREATDQVFFGATVGLLRGDG
                     REQTVKIVGIDEIDTAQNKISWISPLARCLIKAREGDEVVLNTPEGREEIEILSVEYI
                     KID"
     gene            complement(1303..2847)
                     /gene="purF"
                     /locus_tag="ACFOAE_000392"
     CDS             complement(1303..2847)
                     /gene="purF"
                     /locus_tag="ACFOAE_000392"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFC6883952.1"
                     /translation="MCGVLGLVSHAPVNQLLYDGLQMLQHRGQDAAGIATAEGGTFHM
                     HKGKGMVREVFRTRNMRDLTGNAGIAHVRYPTAGNAGSSAEAQPFYVSSPFGIVLAHN
                     GNLTNTAELYENVCNKHLRHINTGSDSEVLLNVFAHELRLEVSKNAEPYRLNADNIFN
                     AVAEVHRLVRGAYGVVAMIAGYGMLAFRDPYGIRPLVLGSQTDSEGRKSYAVASESVA
                     FNALTYDLERDIRPGEAVFVGFDGTMIARQCSDRAKLSPCLFEYVYFARPDSVIDGVS
                     VYQSRLDMGVSLAEKIKRELPVDGIDVVMPIPDTSRPSAMELAVHLDKPYREGLIKNR
                     YIGRTFIMPGQATRKKSVRQKLSPMETEFAGKSVLLVDDSIVRGTTSREIVEMVRAAG
                     ARKVYIASAAPEVRYPNVYGIDMPTREELIANGRSAAEIAAEIGADGIVFQDLGDLEA
                     VVKALNPKIESFDSSCFNGIYQTGDIDDAYLDRLSAEKSGCGGLKIHPSRMEHSISIS
                     DAGDEE"
     gene            complement(3160..3657)
                     /locus_tag="ACFOAE_000393"
     CDS             complement(3160..3657)
                     /locus_tag="ACFOAE_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFC6883953.1"
                     /translation="MNNLPVADLLVFAIIAACIVISTMRGVIAEAGSMAAWVVSFFFA
                     KLFAAPFADLAFASFQPRLFALALSFISLFVIACLIQKMLRSLLTGAVSAVGLGFANR
                     ILGGVFGALKGVLIVTLLVMLASKTDLPDTEEWRQSYTVPFFVSLSEAVLNHADDSDG
                     ALEDD"
     gene            complement(3650..4648)
                     /gene="ftsN"
                     /locus_tag="ACFOAE_000394"
     CDS             complement(3650..4648)
                     /gene="ftsN"
                     /locus_tag="ACFOAE_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HFC6883954.1"
                     /translation="MSENKQNEVLSGYEQLKRRNRRRLVTASCLVAASCILLAAALSS
                     GPAEQTAGETSGVENKAAGAAQTPALKSAADKPQDLAGEDKPSAADSEISEPENVGAP
                     LVLINDRLEDSNIKGLEASEKLQQAETAKTAPKQAKQRAAEKVPATADSTDTVAVEKP
                     KRTAETKPQKAERTAKAKPKAKETKTAEKVADKPKTAAEKTKPDTAKSDSAVKEAKKA
                     DKAESKKTAEKDRSDGKKHETAQKTDKADKTKTAEKEKSGKKAAIQAGYAEKERALSL
                     QRKMKAAGIDSTITEIMTDNGKVYRVKSSNYKNARDAERDLNKLRVHGIAGQVTNE"
     gene            complement(4661..5935)
                     /gene="folC"
                     /locus_tag="ACFOAE_000395"
     CDS             complement(4661..5935)
                     /gene="folC"
                     /locus_tag="ACFOAE_000395"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HFC6883955.1"
                     /translation="MKTLQDWLSHLETAHSGGLIDMGLERVGEVKKRMKLTPQCPVVV
                     VAGTNGKGSVCAYLTQIYKQAGFKVGTLTSPHLLRYNERIAVNAEPVSDDTIIASFER
                     IEAARGEISLTYFEFNALAAVDIFMREQVDVMILEVGLGGRLDAVNAFDGDCAVVTSV
                     DLDHQAFLGDTVEQVGFEKAGVFRSGKPAICGQNPAPKSLLSHAEAIGAKLLMVQRDF
                     EFHAMENIQWNYRFRPQHSDGPARNRNALPFPALRGTYQLSNAACALTVLECLNDKLP
                     VDIGAIKRGLLLVENPGRFQVLPGRPLTVLDVGHNPHAARALRRSLINLAFAQKRTAV
                     FSMLSDKDIDGVLEIVKDQFDEWYIAPLDVPRGMTLESLQNKLHEHSIENIQTFAAVR
                     EAYRAAASKAGENDRIVVFGSFHTVADVMSVL"
     gene            complement(5967..6413)
                     /locus_tag="ACFOAE_000396"
     CDS             complement(5967..6413)
                     /locus_tag="ACFOAE_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HFC6883956.1"
                     /translation="MRAFQTALRPSRILNILTVSLHSASLAVCLTWFYGRMMWFGLAA
                     LAASYAYSLRITNLKHRHAITAITIDRDGQAEIVSGKEKTAKAAALSGSSMVTPYALF
                     LQWDTGGKTVRHCITHDMADPESYRRLKVWVLWRQPKKTAETDTPS"
     gene            complement(6418..6777)
                     /locus_tag="ACFOAE_000397"
     CDS             complement(6418..6777)
                     /locus_tag="ACFOAE_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883957.1"
                     /translation="MYFVDRTAVVLKPTARFLEWLKSTDENMPDLTIEQLRANCSVFL
                     VPQFDEPEAVVSYFDERYRQIFEAELAGWDINKDKWPQDMGLKAFWEFFDIEIHDMVL
                     DMEEAELNITPVFDNMM"
     gene            complement(6850..7578)
                     /locus_tag="ACFOAE_000398"
     CDS             complement(6850..7578)
                     /locus_tag="ACFOAE_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFC6883958.1"
                     /translation="MIKFKNVHKHFKDLHVINGVNLEIKKGEVVVVCGPSGSGKSTLI
                     RTVNQLESIESGEIWVDGVNVADPKTDLNKIREEVGFVFQGFNLYPHLTVLENITLAP
                     MKVKGQNAEQAEKKAMELLERVGLAHKKDAFPSQLSGGQQQRVAIARGLAMEPRVMLF
                     DEPTSALDPEMVGEVLKVMKDLAESGMTMMCVTHEMGFAREVADRVIFVDKGQILEDE
                     TPEAFFTNPKHERAKQFLQQVMTH"
     gene            complement(7751..8530)
                     /gene="rsmA"
                     /locus_tag="ACFOAE_000399"
     CDS             complement(7751..8530)
                     /gene="rsmA"
                     /locus_tag="ACFOAE_000399"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFC6883959.1"
                     /translation="MKEHKARKRFGQNFLQDTRIISDIVNAVRPQADDVVIEIGPGLA
                     AITEPLAKKLNRLHVVEIDRDIVCRLKTLPFADKLVIHEGDVLQFDFNGIAGKKKIVG
                     NLPYNISTPLLFKLAEVADDVVDMHFMLQKEVVDRMVAAPKSNDYGRLGVMLQYFFDM
                     EMLIDVPPESFDPAPKVDSAVVRMIPVKHRIGKADDFEHFAKLVKLAFHQRRKTIRNN
                     LKELAGDDDLQAVGINPQDRAEHIAPEKYVALSNYLAGKTV"
     gene            8742..9431
                     /locus_tag="ACFOAE_000400"
     CDS             8742..9431
                     /locus_tag="ACFOAE_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFC6883960.1"
                     /translation="MLFESLPCLAVWCKNRLSAVLPVGGLNVSENLLEIETHPFDSVL
                     PPKAAVMMMGTFPPKEDKRAMQFHYPNFQNDMWRVYGLVFFNDAAHFQRLSEKAFDAE
                     KIKAFLRERGIASCPTVLKAAREHGNASDKFLKVVETVDLAAVLAKIPDCRHICTTGG
                     KATEILLDIQGGGIKMPKTGETVPFPFAGRDLTLTRLPSTSRAYPLSLAKKAAAYRVF
                     FEMAGLCEKQL"
     gene            9514..10716
                     /gene="trpB"
                     /locus_tag="ACFOAE_000401"
     CDS             9514..10716
                     /gene="trpB"
                     /locus_tag="ACFOAE_000401"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HFC6883961.1"
                     /translation="MKNYHAPDEKGFFGEHGGLFVSETLIPALQELADAYKAAKNDPE
                     FWAEFHRDLKHYVGRPSPVYHAARLSEHLGGAQIWLKREDLNHTGAHKVNNTIGQALL
                     AKRMGKKRVIAETGAGQHGVASATVAARFGMTCDVYMGADDIQRQMPNVFRMKLLGAN
                     VVGVESGSRTLKDAMNEAMREWVARVDDTFYIIGTAAGPTPYPEMVRDFQCVIGNEAK
                     AQMQEAIGRQPDVAVACVGGGSNAIGLFYPYIEEENVRLVGVEAGGLGVDTPDHAAPI
                     TSKAPIGVLHGFRSYLMQDENGQVLGTHSVSAGLDYPGIGPEHSHLHDIKRVEYTAAK
                     DDEALEAFDLLCRFEGIIPALESSHAVAWAVKNAPKMGKDQVILVNLSGRGDKDINTV
                     AKLKGIKL"
     gene            complement(10895..15496)
                     /gene="iga"
                     /locus_tag="ACFOAE_000402"
     CDS             complement(10895..15496)
                     /gene="iga"
                     /locus_tag="ACFOAE_000402"
                     /EC_number="3.4.21.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IgA-specific serine endopeptidase
                     autotransporter"
                     /protein_id="HFC6883962.1"
                     /translation="MKTKRFKINAISLSIFLAYALTPYSEAALVRDDVDYQIFRDFAE
                     NKGKFFVGATDLSVKNKQGQNIGNALSNVPMIDFSVADVNRRTLTVIDPQYAVSVKHV
                     KGDEISYYGHHNGHLDVSNDENEYRSVAQNDYEPNKNWHHGNQGRLEDYNMARLNKFV
                     TEVAPIAPTSAGGGVETYKDKNRFSEFVRVGAGTQFEYNSRYNMTELSRAYRYAIAGT
                     PYQDVNVTSNLNQEGLIGFGDNSKHHSPEKLKEVLSQNALTNYAVLGDSGSPLFAYDK
                     QEKRWVFLGAYDYWAGYQKNSWQEWNIYKKEFADKIKQRDNAGTIKGYGEHHWKTTGT
                     NSHIGSTAVRLANNERDANNGQNVTFEDNGTLVLDQNINQGAGGLFFKGDYTVKGANN
                     DITWLGAGIDVADGKKVVWQVKNPNGDRLAKIGKGTLEINGTGVNQGQLKVGDGTVIL
                     NQQADADKKVQAFSQVGIVSGRGTLVLNSSNQINPDNLYFGFRGGRLDANGNDLTFEH
                     IRNVDEGARIVNHNTSHASTITLTGKSLITDPKTISIHYIQNNDDDDDGYYYYRPRKP
                     IPQGKDLYFKNYRYYALKSGGSVNAPMPENGQTENNDWVFMGYKQEEAQKNAMNHKNN
                     QRISGFSGFFGEENGKGHNGALNLNFNGKSAQNRFLLTGGTNLNGKISVTQGNVLLSG
                     RPTPHARDFVNKSSARKDAHFSKNNEVVFEDDWINRTFKATEIAVNQSASFSSGRNVS
                     NITANITATDNAKVNLGYKNGDEVCVRSDYTGYVTCNTDNLSDKALNSFDATQINGNV
                     NLNQNAALVLGKAALWGQIQGQGNSSVSLNQHSKWHLTGDSQVHNLSLADSHIHLNNA
                     SDAQSANKYHTLKINHLSGNGHFHYLTHLAKNLGDKVLVKESASGHYQLHVQDKTGEP
                     NQEGLDLFDASSVQDRSRLSVSLANNHVDLGALRYTIKTENGITRLYNPYAENRRRVK
                     PAPSPATNTASQAQTDSAQIAKPQNIVVAPPSPQANQAEEAKRQQAKAEQVKRQQAEA
                     EKVAHQKAEEAKRQQDALARQQAEQERQRLEAERQAAEIAKQKAEAEEAKRQAAELAR
                     QQEEARKAAELAAKQKAETERKAAEIAEQKAEAEREAAELAKQKAEEEGRQAAQSQPK
                     RRNRRAIPPELSSDATTRALPRIARNSNPDASDYEEIPLDALEDEDVSESVDTSDKQP
                     QDNTELHEKVETVSLQPRAAQPRAQAAAQPQAQAAAQADAVSTNTNSALSDAMASTQS
                     ILLDTGASLTRHIAQKSRADAEKNSVWMSNIGYGRDYASAQYRRFSSKRTQTQIGIDR
                     SLSENMQIGGVLTYSDSQHTFDQASGKNTFVQANLYGKYYLNDAWYVAGDIGAGSLRS
                     RLQTQQKANFNRTSIQTGLTLGNTLKINQFEIVPSAGIRYSRLSSADYKLGNDSVKVS
                     SMSVKTLTAGLDFAYRFKVGNLTVKPLLSAAYFANYGKGGVNVGGNSFAYKADNQQQY
                     SAGAALLYRNVTLNVNGSITKGKQLEKQKSGQIKIQIRF"
     gene            16466..18685
                     /locus_tag="ACFOAE_000403"
     CDS             16466..18685
                     /locus_tag="ACFOAE_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFC6883963.1"
                     /translation="MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFA
                     FAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVPLTVEVADMPRSDGRRVQFAAKA
                     VDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
                     GTVGADRVLLHGGSGWGVAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRP
                     ELWQAFRPLGLTHLVSISGLHVTMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAG
                     ALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALAAVLLFDPSAVLGVG
                     TWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLISPLVNA
                     VAIPWFSWVLTPLALLGSVVPFAPLQQLGAFLAEYTLRFLVWLADVSPEFAVASAPLP
                     LLVLAVCAALLLLLPRGLGLRPWAVLLLAGFVFYRSPGVPENEVAVTVWDAGQGLSVS
                     VQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQAVGKIPN
                     GGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAAL
                     LVTGDLDTKGEESLVGKYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYA
                     NAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGGVKAQRLRGYKFYWQKKPFE"
     gene            complement(18743..19546)
                     /locus_tag="ACFOAE_000404"
     CDS             complement(18743..19546)
                     /locus_tag="ACFOAE_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HFC6883964.1"
                     /translation="MKKILLTVSLGLALSACATQGTVDKDAQITQDWSVEKLYAEAQD
                     ELNSSNYTRAVKLYEILESRFPTSRHARQSQLDTAYAYYKDDEKDKALAAIERFRRLH
                     PQHPNMDYALYLRGLVLFNEDQSFLNKLASQDWSDRDPKANREAYQAFAELVQRFPNS
                     KYAADATARMIKLVDALGGNEMSVARYYMKRGAYIAAANRAQKIIGSYQNTRYVEESL
                     AILELAYQKLGKPQLAADTRRVLETNFPKSPFLTHAWQPDDMPWWRYWH"
     gene            19545..20669
                     /gene="rluD"
                     /locus_tag="ACFOAE_000405"
     CDS             19545..20669
                     /gene="rluD"
                     /locus_tag="ACFOAE_000405"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HFC6883965.1"
                     /translation="MQNTSFDNESDYSDDSDFVSASETENRIGLTVPLELAGGRLDAV
                     LAKLLPDYSRSRLTSWIKEGAVIVNDKPSQPKDKMIGGEQICVTVRPSEENLAFVPEP
                     MALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPELSQIPRAGIVHRLD
                     KETSGLMVVAKTLPAQNSLVRQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHNRL
                     KMAVVKFGGKPAVTHVKVLERYLAHSYIECSLETGRTHQIRVHMREANHPLAADPVYG
                     NPRHPCGDTVKEAVKSLGARQALHAYRLSFTHPKTGETVSFEAPIPNDIYHLLSVLRL
                     EAGLDSSLSNEEEWQDKFGADDDDDWNEDDYDVEVVYVRE"
     gene            complement(20822..21769)
                     /locus_tag="ACFOAE_000406"
     CDS             complement(20822..21769)
                     /locus_tag="ACFOAE_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HFC6883966.1"
                     /translation="MNILSKISSFIGKTFSLWAALFAAAAFFAPDTFKWAGPYIPWLL
                     GIIMFGMGLTLKPSDFDILFKHPKAVIIGVIAQFAIMPATAWLLSKLLNLPAEIAVGV
                     ILVGCCPGGTASNVMTYLARGNVALSVAVTSVSTLISPLLTPAIFLMLAGEMLEIQAA
                     GMLMSIVKMVLLPIVLGLIVHKVLGSKTEKLTDALPLVSVAAIVLIIGAVVGASKGKI
                     MESGLLIFAVVVLHNGIGYLLGFFAAKWTGLPYDAQKTLAIEVGMQNSGLAAALAAAH
                     FAAAPVVAVPGALFSVWHNISGSLLATYWAAKAGKHKKP"
     gene            22375..23154
                     /gene="pgeF"
                     /locus_tag="ACFOAE_000407"
     CDS             22375..23154
                     /gene="pgeF"
                     /locus_tag="ACFOAE_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HFC6883967.1"
                     /translation="MKTITETLNLAPKGKNFLTADWPAPANVKTLITTRNGGVSQGAY
                     QSLNLGTHVGDNPEAVRRNREIVQQQVGLPVAYLNQIHSTVVVNAAEALGGTPDADAS
                     VDDTGKVACAVMTADCLPVLFCDRAGTAVAAAHAGWRGLAGGVLQNTIAAMKVPPVEM
                     MAYLGPAISADAFEVGQDVFDAFCTPMPEAAAAFEGIGGGKFLADLYALARLILKREG
                     VGGVYGGTHCTVLERDTFFSYRRDGATGRMASLIWLDGNAV"
     gene            23206..23685
                     /gene="lptE"
                     /locus_tag="ACFOAE_000408"
     CDS             23206..23685
                     /gene="lptE"
                     /locus_tag="ACFOAE_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0019867 - outer membrane [Evidence IEA];
                     GO_process: GO:0043165 - Gram-negative-bacterium-type cell
                     outer membrane assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HFC6883968.1"
                     /translation="MNKLFLTAAVLMLGACGFHLKGADGISPPLTYRSWHIEGGQALQ
                     FPLETALYQASGRVDDAAGAQMTLRIDSVSQNKETYTVTRAAVINEYLLILTVEAQVL
                     KRGEPVGKPMIVSVRRVLAYADNEILGKQEEEAALWAEMRQDAAEQIVRRLTFLKAE"
     gene            23687..24685
                     /gene="holA"
                     /locus_tag="ACFOAE_000409"
     CDS             23687..24685
                     /gene="holA"
                     /locus_tag="ACFOAE_000409"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFC6883969.1"
                     /translation="MAAHIGRIDTDAPLKPLYVIHGEEELLRIEALDALRAAAKKQGY
                     LNREVYTADNAFDWNELLQTAGSAGLFADLKLLELHIPNGKPGKTGGEALQDFAARLP
                     EDTVTLVLLPKLEKTQLQSKWFAALAAKGEVWEAKPVGAAALPQWIRGRLDKIGLGIE
                     ADALALFAERVEGNLLAARQEIDKLALLYPKGHTVNIDEAQTAVANVARFDVFQLAGA
                     WMKGDVPRVCRLLDGLREEGEEPVLLLWAVAEDIRTLIRLAASLKQGQSVQSVRNSLR
                     LWGEKQTLAPLAVKRISVVRLLDALKTCAQIDRIIKGAEDGDAWTVFKRLVVSLAE"
     gene            24806..25225
                     /locus_tag="ACFOAE_000410"
     CDS             24806..25225
                     /locus_tag="ACFOAE_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883970.1"
                     /translation="MDNKTKLRLGGLILLTTAVLSLIIVLIVDSWPLAILLAAVIVAA
                     AAGGFVWTSRRQQRQFIERLKKFDIDPEKGRINEANLRRMYHSGGQHQKDAITLICLS
                     QKCSVDEAHAMFKKRPTRQEINQMAAKQSRGQKRPHR"
     gene            25301..25816
                     /locus_tag="ACFOAE_000411"
     CDS             25301..25816
                     /locus_tag="ACFOAE_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFC6883971.1"
                     /translation="MMTLKTAPLKRRFAAMLYEMLLVGAATCLAALFAGIAAIFLNPV
                     SIAVSALVTSILIMGSWWLYFRANWHGQGQTLAMRTWKIGLCDLNGIQPSLYLLRLRF
                     IWACIFIVFIPMLAYAGLRHFLGIPPKGAAGAALIWLILPWGFALLNPDRQFLYDFLA
                     GTRLVAVKGKP"
     gene            complement(25900..26784)
                     /locus_tag="ACFOAE_000412"
     CDS             complement(25900..26784)
                     /locus_tag="ACFOAE_000412"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFC6883972.1"
                     /translation="MSSGNIHIHSMTGFANAAAECGSKRINLDLRAVNHRFLDIQIRM
                     PDDLRYLESGIREKISSHIARGKVECKIQIQDAENGNQSLELNRDLVGQLAEINKDLR
                     KHYDLAKLGVADILRFPGVLASQRENADALAKVIADLTDSALKDFTAARRREGKKLGE
                     HLLQRLESMEEIIDALSELFPTLLETHKEKIRARLAEAVGSIDNDRLQQEFALFIQKS
                     DIDEEFSRLRTHIAEVRRIVTEHKGSSGKRLDFLMQELNREANTLGSKSIATECTQAS
                     VELKVLIEQMREQVQNIE"
     gene            complement(27268..28131)
                     /gene="rpoH"
                     /locus_tag="ACFOAE_000413"
     CDS             complement(27268..28131)
                     /gene="rpoH"
                     /locus_tag="ACFOAE_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HFC6883973.1"
                     /translation="MNNAFALPAIQSGNGSLEQYIHTVNSIPMLSQEEETRLAERRIK
                     GDLNAAKQLILSHLRVVVSIARGYDGYGLNQADLIQEGNIGLMKAVKRYEPGRGARLF
                     SFAVHWIKAEIHEFILRNWRLVRVATTKPQRKLFFNLRSMRKNLNALSPKEAQDIADD
                     LGVKLSEVLEMEQRMTGHDIAIMADNSDDEDSFAPIDWLADHDSEPSRQLSKQAHYAL
                     QTEGLQNALAQLDDRSRRIVESRWLQDDGGLTLHQLAAEYGVSAERIRQIEAKAMQKL
                     RGFLTEEAEAV"
     gene            complement(28395..29933)
                     /gene="lnt"
                     /locus_tag="ACFOAE_000414"
     CDS             complement(28395..29933)
                     /gene="lnt"
                     /locus_tag="ACFOAE_000414"
                     /EC_number="2.3.1.269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016410 - N-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HFC6883974.1"
                     /translation="MFSKLDKYWQHPALYWPLLILFAAATPFTFAPYYHFWLMPLIFG
                     AFVRLIELRPRFAVSSAYLFSLTAYTTQFYWIHTALHDVSGLPDLYAVPLTFLLPAYL
                     ALYPALCFWLWKKFTLPRGIKIGLVLPILWTLTEFARERFLTGFGWGAIGYSQITPDS
                     PLAGFAPLGGIHMVTLATAFLGVWLVLASDNTARSGKRLLPIILIAALLAAGYTARQT
                     DFTRPDGSRSTVALLQGNIDQTLKWREDQVIPTIQKYYEQVGKTTADIVILPETAIPV
                     MRQNLPENILAKFAEQAQNNGSALAVGISQYTSDGNGYENAVINLTGYQENNQDGIPY
                     YAKNHLVPFGEYKPLPFLTTPLYKMMNMPLSDFRKGGGKQSALLMKNQKIAFNICYED
                     GFGDELIAAAKDATLLANASNMAWYGKSNAMYQHLQQSQARAMELGRYMVRATNTGAT
                     AIISPKGNIIAQAQPDTETVLEGHIKGYVGETPYMKTGSSWWLMGILTLAALILFIFR
                     NKEH"
     gene            complement(30002..30728)
                     /locus_tag="ACFOAE_000415"
                     /pseudo
     CDS             complement(30002..30728)
                     /locus_tag="ACFOAE_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 family protein"
     gene            30924..31244
                     /locus_tag="ACFOAE_000416"
     CDS             30924..31244
                     /locus_tag="ACFOAE_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium:proton antiporter"
                     /protein_id="HFC6883975.1"
                     /translation="MDWMGSLFLPGGALLFLSVVSTTLPARLGMPLLLVSPAGVLDGA
                     AEALAIAAFLMLVARPPAVFGGLWKFNYSLREKAYSRIEMQSDTVLQAGIWRGTSCPT
                     ARSI"
BASE COUNT         6626 a         7638 c         8896 g         8086 t
ORIGIN      
        1 tcattccggc ggcaattttt gttgctttaa cgggataggc ggttggcggt tgcgataaag
       61 gcggcgactt tggctgggtc ttttttgcct ttagacgctt ccacgccgcc ggatacatcg
      121 accgcttccg ctccggtgat gcggacggct tcgccgacgt tttcaggggt cagcccgccg
      181 gcaagcaccc acggtttgcc cgaatattcc gccaacagcg tccagtcgaa gcggtgtccg
      241 gtgccgccgt attccgaagg gtgataggca tcgaacagca gtgcctgagc gttgggaaag
      301 cagtgggcgg cgtttcggat gtctgatgcc gtctgaacac gaatggcttt gatatagggg
      361 cggtcgaact ggcggcagaa tgcgtcgtct tcgtcgccgt ggaattggat gatgtgtatc
      421 ggcacttcgg caaggatgcg gcggatgttt tgcgcgcttt cgttgacgaa aagggcgaca
      481 acgctgacaa acggcggcag tgcggcggtg atttttttgg cgcgggcaat atcgacggcc
      541 cggctgctgc cttggaaaaa gaccagcccg acggcatctg cacctgccgc tgcggcgacc
      601 gatgcgtctt ccggtgtggt gatgccgcag attttggtgc ggattttctt cattcggtat
      661 tcctttattt gggaaacggc gcgtttgtgc cgtttcagac ggcattccta atcagtcgat
      721 tttgatgtat tcgacagaaa ggatttcaat ttcctcacgc ccttccggcg tgttcaaaac
      781 cacttcgtcg ccttcgcgcg ctttaatcag gcaacgcgcc agtggcgaaa tccaagaaat
      841 tttgttttgc gcggtatcga tttcatcgat gccgacaatt ttgacggttt gctcacgccc
      901 gtcgccgcgc aacagcccga ccgtcgcgcc gaaaaacact tggtcggtcg cttcgcgcaa
      961 ttcgggatcg acgacgacgg cagcttccaa acgcttggtc aggaaacgga tgcggcggtc
     1021 gatttcgcgc atacggcgtt tgccgtaaag atagtcgccg ttttcgctgc ggtcgccgtt
     1081 gcctgccgcc cagttgacga tttggacgat ttcggggcgt tctttgttga ccagttgata
     1141 aagctcgtct ttcaatgcct gccatctggc gggcgtaatg tagtttttgg tttcggtact
     1201 catattgtgt gcggatgaaa cgggaaatgt gatgccgata tgggaaatgc cgtctgaaaa
     1261 cccggcgttc ggatttcaga cggcatcgcg gtttgggaag ctttattctt cgtcgcccgc
     1321 atcgctgatg ctgatgctgt gttccatcct gctcgggtgg attttcagac cgccgcagcc
     1381 ggatttctcg gcagacaggc ggtcgaggta ggcatcatcg atgtcgccgg tctgataaat
     1441 gccgttgaaa caggacgaat cgaaagattc gattttcgga ttgagtgctt tgacgacggc
     1501 ttccaaatcg cccaagtctt gaaacacgat gccgtccgcg ccgatttcgg cggcgatttc
     1561 cgccgcgctg cgcccgttgg caatcaactc ttcgcgcgtg ggcatatcga tgccgtatac
     1621 gttgggatag cgcacttcgg gcgcggcgga ggcgatatag actttgcgcg cgcccgccgc
     1681 gcgtaccatt tcgacgattt cgcggctggt cgtcccgcgc acgatggagt cgtccaccag
     1741 caacacgctt ttgcctgcaa attcggtttc catcgggctg agtttttggc gcacggattt
     1801 tttgcgcgtc gcctgtccgg gcataataaa ggtgcggccg atatagcggt ttttaatcaa
     1861 accctcgcgg tagggtttgt cgagatggac ggcaagctcc atcgcgctgg ggcggctggt
     1921 gtcgggaatg ggcatcacga catcgatgcc gtccacgggc agctcgcgtt tgattttttc
     1981 cgccagcgac acgcccatat ccaagcgcga ttggtaaacg gatacgccgt caatcacaga
     2041 gtcggggcgg gcaaaataaa catattcaaa aaggcagggg ctgagtttgg cacggtcgct
     2101 gcattggcgg gcaatcattg tgccgtcaaa gccgacaaat accgcttcgc ccggccggat
     2161 gtcgcgttcc aaatcgtagg taagcgcgtt gaaggcgacg gattcggagg cgacggcata
     2221 ggattttctg ccttcgctgt cggtttgcga acccaatacc agcgggcgga tgccgtaagg
     2281 gtcgcggaag gcgagcatac cgtagcccgc aatcatggca accacgccgt atgcgccgcg
     2341 caccaggcgg tggacttcgg caacggcgtt gaaaatattg tcggcattga gccggtaagg
     2401 ttcggcgttt ttggagactt cgaggcgcaa ttcgtgcgcg aatacgttga gcaagacttc
     2461 ggaatcggag ccggtgttga tgtggcgcag gtgtttgttg cacacgtttt catacagttc
     2521 ggccgtgttg gtgaggttgc cgttgtgtgc caaaacgatg ccgaacggcg agctgacgta
     2581 gaaaggctgc gcctccgcgc tgctgccggc gttgcccgcc gtgggataac ggacgtgggc
     2641 gatgccggcg ttgccggtca aatcgcgcat attgcgtgta cggaacactt cgcgcaccat
     2701 gcctttgcct ttgtgcatat ggaacgtgcc gccttccgcc gttgcaatgc ccgccgcatc
     2761 ctgtcccctg tgctgcaaca tctgcaagcc gtcgtacaga agctggttca cgggtgcatg
     2821 actgaccaaa cctaatacgc cgcacatatc gtcttctccg attcgaggtt taagggtaaa
     2881 acggaattat aaagcaaacg gtggtttttt gcctgaattg ttgacaatat ttgagcgaag
     2941 gacagatagg cgggtttatg gaggataaga tttatagtgg attaacaaaa atcaggacaa
     3001 ggcgacgaag ccgcagacag tacaaatagt acggcaaggc gaggcaacgc cgtactggtt
     3061 taaatttaat ccactataat ctgtgatatg gcagaggaaa ggaaaaaaac atttcagacg
     3121 gcataaaaga ggatgccgtc tgaaatatcc gtatggcaat caatcgtctt ccaaagctcc
     3181 atcactgtcg tccgcatggt ttaacactgc ttcggaaagc gacacgaaaa acggtacggt
     3241 ataggactgc cgccattctt cggtatcggg caggtcggtt tttgaagcaa gcatgaccag
     3301 cagggtaaca atcaaaacgc ctttcaatgc accgaatacg ccgcccaaaa tgcggttggc
     3361 aaagcccaaa ccgaccgccg aaactgcgcc ggtcagcagc gaacggagca ttttctggat
     3421 cagacaggca atgacgaaca gggaaatgaa cgacagagcc aatgcaaaca ggcggggttg
     3481 gaacgaggca aaggcgaggt cggcgaaggg tgcggcaaag agtttggcaa aaaagaagga
     3541 aaccacccat gccgccatcg aacctgcctc cgcaatcacg ccgcgcatcg tggaaatgac
     3601 gatgcaggcg gcgatgatgg cgaagacgag gaggtcggca acggggaggt tattcattcg
     3661 ttacctgacc ggcgataccg tgtacgcgca atttgttcaa atcgcgttcg gcatcccttg
     3721 cgtttttata gttgcttgat ttgacgcggt aaactttgcc gttgtcggtc ataatttcgg
     3781 tgatggtcga atcgataccc gccgccttca ttttgcgctg gaggcttaag gcgcgttctt
     3841 tttcggcata acctgcctga atggcggctt ttttaccgga tttttccttc tcggcggttt
     3901 tggtcttgtc cgctttgtcg gttttttgtg ccgtttcgtg ttttttgccg tccgaacggt
     3961 ctttttcggc tgtttttttg ctttcagcct tgtcggcttt tttcgcttct tttaccgcgc
     4021 tgtcggattt tgccgtatcc ggtttggttt tttcggcggc agttttcggt ttgtcggcaa
     4081 ctttttcggc ggttttggtt tctttggctt tgggcttggc tttggcagtg cgttccgctt
     4141 tttgcggttt tgtttcggca gtgcgtttcg gtttttcaac cgctaccgta tccgtactgt
     4201 cggcagttgc cggcactttt tcggcagcgc gttgttttgc ctgcttcggt gcggttttgg
     4261 cggtttctgc ctgttgcagt ttctcggatg cttccaaacc tttgatgttg ctgtcttcga
     4321 ggcggtcgtt aatcagcacc agcggcgcgc ctacgttttc aggctcgctg atttcgctgt
     4381 cggcggcaga aggcttgtct tcgcctgcca agtcctgcgg tttgtcggcg gcggatttca
     4441 aggcaggggt ttgtgccgca cctgccgctt tgttttctac gccgcttgtt tcgccggcag
     4501 tctgttcggc agggccggaa ctgagggcgg ctgccagcag gatgcaggag gcggcaacca
     4561 ggcaacttgc cgttacgagg cggcggcggt tgcgccgttt gagttgttcg taaccgctca
     4621 ggacttcgtt ttgtttgttt tcggacatag aagtttcctt ttaaagtacc gacatgacat
     4681 cggcaacggt atgaaatgag ccgaaaacga cgattctgtc gttctcgccc gcttttgagg
     4741 ctgccgcccg gtatgcttcg cggacggcgg cgaatgtctg tatgttttcg atgctgtgtt
     4801 cgtgcagttt gttttgcagg ctctcgagcg tcatgccgcg cggtacgtcc aacggtgcga
     4861 tataccactc gtcaaactgg tctttaacga tttccaacac gccgtctatg tctttgtcgg
     4921 acagcatact gaatacggcg gtgcgttttt gcgcaaacgc caaattaatc aggctgcggc
     4981 gcagggcgcg ggcagcgtgg ggattgtgtc cgacatccaa aacggtcagc ggacggccgg
     5041 gcaggacttg gaagcggccg gggttttcaa ccagcagcaa accgcgtttg atggcgccga
     5101 tgtccacagg caatttgtcg ttcaagcatt ccaatacggt caacgcgcag gcggcgttgg
     5161 aaagctggta tgtgccgcgt aatgcaggga aaggcagggc attgcggttg cgtgcggggc
     5221 cgtctgaatg ttgcggccgg aagcggtagt tccattggat gttttccatc gcgtgaaact
     5281 cgaaatcgcg ctgcaccatc agcagtttcg cgcctatggc ttcggcgtgt gaaagcaacg
     5341 atttgggcgc ggggttttga ccgcagatgg cgggtttgcc gctgcggaac acgcctgctt
     5401 tttcaaagcc gacctgctcg accgtatcgc ccaaaaatgc ctgatggtcc aaatccacgc
     5461 tggtaaccac cgcgcaatcg ccgtcaaacg cgttgaccgc gtccaagcgt ccgcccaagc
     5521 cgacttccaa tatcatcacg tcaacctgtt cgcgcatgaa gatgtcgacc gccgccaagg
     5581 cattgaattc aaaataagtc agcgatattt cgccgcgcgc cgcttcgatg cgctcgaaag
     5641 aggcaataat cgtatcgtcc gaaacgggtt cggcgttgac ggcgatgcgt tcgttgtaac
     5701 gcaataaatg cgggctggtc agcgtaccga ctttaaagcc tgcctgtttg taaatctgtg
     5761 tcaggtaggc gcagaccgaa cctttgccgt ttgttcccgc gacaacgacg acggggcatt
     5821 gcggcgtgag cttcatccgt tttttcactt cgcctacgcg ttccaagccc atatcgatca
     5881 agccaccgct gtgggcggtt tccaaatggg agagccagtc ttgcagtgtt ttcattgagt
     5941 gttccgtgtt caaatgccgt ctgaaatcag cttggtgtat cggtttcggc ggtttttttc
     6001 ggctgccgcc aaagcaccca gactttcagc cgccggtagg attccgggtc cgccatatcg
     6061 tgggtgatgc agtggcggac ggttttgccg ccggtgtccc attgtaagaa taaggcataa
     6121 ggcgtaacca tactgctgcc cgacagtgcc gccgcctttg ccgttttttc tttgccggat
     6181 acgatttccg cctgtccgtc gcggtctatg gtaatggcgg ttatggcatg gcggtgtttc
     6241 agattcgtta tcctgagcga gtatgcgtaa cttgccgcca aagccgccaa accgaaccac
     6301 atcatccggc cgtaaaacca ggtcaggcag acggcaaggg aagccgagtg gagcgatacg
     6361 gtcaggatgt tcaggatgcg ggacggcctc aatgccgtct gaaaggcgcg cacagcctta
     6421 catcatgttg tcgaacacgg gggtaatgtt caattccgct tcttccatgt ccaacaccat
     6481 atcgtggatt tcgatgtcga aaaattccca aaacgccttc agccccatat cttgcggcca
     6541 tttatcctta ttgatgtccc aacctgccag ctccgcctcg aaaatctggc ggtagcgttc
     6601 gtcgaagtag gaaacgacgg cttccggttc gtcgaactgc ggaacgagga agacggaaca
     6661 gttggcacga agctgctcta tggtcaggtc gggcatattt tcgtcggtgc ttttgagcca
     6721 ttccaaaaag cgcgcggtcg gcttgaggac gacggcggtg cggtcaacaa aatacatggt
     6781 tttctttctc aatcatcttg cggtgtcggg atatgctgtc tgaacgttcg gttttcagac
     6841 ggcatagcat caatgggtca tgacctgttg caggaactgc ttggcgcgtt cgtgtttcgg
     6901 gttggtaaaa aacgcttcgg gcgtttcgtc ttcgaggatt tgccctttat cgacgaaaat
     6961 cacgcggtcg gcaacttcgc gggcaaaccc catttcgtgg gttacgcaca tcatcgtcat
     7021 gccgctttct gccaagtctt tcatcacttt caacacttcg ccgaccattt cggggtcgag
     7081 tgcggaggtc ggttcgtcaa acaacattac gcgcggttcc atcgccaaac cgcgtgcaat
     7141 cgccacgcgt tgctgctggc cgccggaaag ttgggaaggg aaggcgtctt ttttgtgtgc
     7201 cagtccgacg cgttccaaaa gctccattgc ctttttctcc gcctgttccg cattttgccc
     7261 cttaaccttc atcggtgcga gggtaatgtt ttccaacacg gtcaggtgcg ggtagaggtt
     7321 gaagccttgg aatacgaagc cgacttcttc gcggattttg ttcaaatcgg ttttggggtc
     7381 ggcaacgttg acaccgtcca cccaaatctc gccgctttcg atgctttcaa gctggttgac
     7441 agtgcggatg agtgtggatt tgccgctgcc cgaaggcccg cagacgacga ccacttcgcc
     7501 ttttttgatt tccaagttta cgccgttgat gacgtgcagg tctttgaaat gtttgtgtac
     7561 gtttttgaat ttgatcatgt cttttctttc agacggcatt tgccgttgca ggttgtcgtt
     7621 acgggagctc catatgatga agcgtgtagc gtctgccgtc aaaaaaacgg tcgttcggat
     7681 tggtcaggca ggctgcaagc ggcagtatca ggggtaaaag caggtatttc gtcatcggct
     7741 tactcccttt tcagacggtc ttgcccgcca gataattgct caacgccaca tatttctccg
     7801 gcgcgatatg ttcggcgcgg tcttgcggat tgatgccgac tgcctgcaaa tcatcgtcgc
     7861 ctgcaagctc tttcagattg ttgcgtatgg ttttgcggcg ttggtggaag gcgagtttca
     7921 cgagtttggc gaaatgctcg aaatcgtccg ccttgccgat acggtgtttc accggaatca
     7981 tgcggacgac ggccgaatcc actttcggcg cggggtcgaa cgattcgggc ggcacgtcaa
     8041 tcagcatttc catatcgaag aaatattgca gcatcacgcc caagcggccg tagtcgttgc
     8101 ttttcggcgc ggcaaccata cgatcgacca cttctttttg cagcataaag tgcatatcga
     8161 cgacatcgtc cgccacctcc gccagcttga acaaaagcgg cgtggaaatg ttgtagggca
     8221 ggttgccgac gattttcttt ttgcctgcga tgccgttgaa atcaaactgc aatacatcgc
     8281 cttcgtgaat caccagttta tccgcaaacg gcagcgtttt cagacggcat acgatgtcgc
     8341 ggtcgatttc gacaacgtgc aggcggttca gctttttcgc caaaggttcg gtaatcgccg
     8401 ccaaacccgg accgatttca atcacgacat catccgcctg cgggcgcacg gcgttgacaa
     8461 tatcgctgat aatccgcgtg tcctgcaaaa aattctgccc gaaacgcttg cgggctttgt
     8521 gttctttcat cgtgtttcct tttcggttga aaccccgcca cttggacatc tgtccttcgg
     8581 ggcggtagaa tcagactcta tttgggaggg gcgtaacccc ttccaaatca ggatggcaca
     8641 tagggcggtg ctttaagtgt cgtcctgtgt gttgaaacat aaatgtgttt acagtatccg
     8701 tttgatgtcg gcattgtaac cgaaaacggc agggcgtgat aatgctgttt gaaagcttgc
     8761 cgtgtttggc ggtttggtgc aaaaaccggc tgtctgccgt tttgcctgtt ggaggattga
     8821 acgtgtctga aaatctgctt gaaatcgaaa cccatccctt cgattccgtg ttgccgccga
     8881 aggctgcggt catgatgatg gggacgtttc cgcccaagga agacaaacgc gcgatgcagt
     8941 ttcattatcc gaatttccaa aacgatatgt ggcgcgttta cgggctggtg ttttttaatg
     9001 atgcggcgca tttccaaagg ttgtctgaaa aagcgtttga tgccgagaaa atcaaggcgt
     9061 ttttgcgcga acggggaatt gcgtcctgtc cgaccgtgtt gaaggcggca agggaacacg
     9121 gcaatgcgtc cgacaagttt ttaaaggtag ttgaaaccgt cgatttggcg gcggtgttgg
     9181 cgaaaatacc agactgccgc catatttgta cgacaggcgg caaggcgacg gaaatcctgc
     9241 tcgatattca gggtggcggc atcaaaatgc cgaaaacggg cgaaaccgtg ccgtttccgt
     9301 ttgccggacg ggatttgacg ctgacgcgcc tgccttcgac ttcgcgcgcc tatcctttga
     9361 gtttggcgaa aaaagcggcg gcgtatcggg tgtttttcga aatggcgggc ttgtgtgaaa
     9421 agcagttata attgccgaca atttcccgtt cggacggcat gtttgaaaaa acggaaatgc
     9481 cgtctgaaaa cctgaagcac aaggaagaat ccgatgaaga actaccacgc gcccgacgag
     9541 aagggctttt tcggcgaaca cggcgggctg ttcgtgtccg agaccctgat tcccgctttg
     9601 caagagctgg cggatgccta taaggcagcg aaaaacgatc ctgaattttg ggcagagttc
     9661 caccgcgatt tgaaacatta tgtcggcagg cccagccccg tttaccacgc cgcgcggttg
     9721 tccgaacatc tgggcggcgc gcaaatctgg ttgaagcgcg aagacttgaa ccacactggc
     9781 gcgcacaaag tcaacaacac catcggtcag gcactgttgg caaaacgcat gggtaaaaaa
     9841 cgcgtcatcg ccgaaactgg cgcgggtcag cacggcgtgg cgagtgccac cgttgccgca
     9901 cgcttcggta tgacttgcga cgtgtatatg ggcgcggacg acatccaacg ccaaatgccc
     9961 aacgtgttcc gtatgaaatt attgggtgcg aacgtggtcg gtgtagaaag cggcagtcgc
    10021 acgctgaaag acgcgatgaa cgaagccatg cgcgaatggg tcgcccgcgt ggatgacaca
    10081 ttctacatca tcggtaccgc cgccggcccc acgccgtatc ccgaaatggt gcgcgatttc
    10141 caatgcgtga tcggcaacga agctaaagcg cagatgcagg aagccatcgg cagacagccc
    10201 gacgttgccg ttgcctgcgt gggcggcggc tccaacgcca tcggtttgtt ctatccctat
    10261 atcgaagaag aaaacgtacg tttggtcggc gtagaagcag gcggtttggg tgtggatacc
    10321 cctgaccacg ccgcaccgat taccagcaaa gcccctatcg gcgtattgca cggtttccgc
    10381 agctatctga tgcaggacga aaacggtcaa gtcttgggta cacactctgt ttccgcaggc
    10441 ttggattacc ccggcatcgg cccggaacac agccatctgc acgacatcaa gcgcgtcgaa
    10501 tacaccgccg ccaaagacga cgaagcactc gaagcctttg acttgctctg ccgcttcgag
    10561 ggcatcatcc ccgcgctcga atccagccac gccgttgctt gggcggtgaa aaatgcgccg
    10621 aaaatgggta aagaccaagt gattttggtc aacctctcag gtcgtggcga caaagacatc
    10681 aataccgtcg cgaagctcaa agggattaaa ctgtaacctc gtccgtctga tatagtggat
    10741 taacaaaaac cagtacggcg ttgcctcgcc ttgccgtact atctgtactg tctgcggctt
    10801 cgtcgccttg tcctgatttt tgttaatcca ctataaaaat gccgtctgaa gcctgagttc
    10861 agacggcatt ttattttgct atgaatttag tattttagaa acgaatctgt attttaattt
    10921 gtccggattt ttgtttttcc aattgtttgc cttttgtaat actgccattt acgtttaatg
    10981 taacattacg gtacagtaac gcggcacctg ctgaatattg ctgttgatta tctgctttat
    11041 aggcgaagga attaccgccc acattcacgc cgcctttgcc ataattggca aagtaagctg
    11101 cagataacaa gggttttacg gtaaggttgc cgactttaaa ccgataagca aaatccagtc
    11161 cggccgtcag tgttttcact gacatagaac ttactttaac actgtcgtta cccaacttgt
    11221 aatctgcaga tgacaggcgg ctgtaacgga ttcccgcact ggggacaatc tcgaattgat
    11281 tgattttcag cgtattgccc aaagtaaggc cggtttggat gcttgttcgg ttaaagtttg
    11341 ctttttgctg cgtttgtaac cggcttctca agctgcctgc accaatatcg ccggccacat
    11401 accaagcatc atttaaataa tacttaccat aaaggttggc ttgcacaaaa gtatttttgc
    11461 cgctcgcctg atcaaaagta tgctgactgt cagagtaagt caatacgccg cctatctgca
    11521 tattttcgga caagctgcgg tcaatgccga tttgtgtttg cgtgcgtttc gaactaaacc
    11581 ggcgatattg tgcggaagca taatcacggc cataaccgat gttcgacatc caaacgctgt
    11641 ttttttcggc atcagcgcgt gatttttgtg caatgtgccg tgttaatgaa gcacctgtat
    11701 ccaacaagat agattgcgtg cttgccattg cgtcagataa agccgagttg gtattggtgc
    11761 tgactgcatc ggcttgcgcg gcggcttggg cttgcggctg cgcggcggct tgggctcgcg
    11821 gctgagcggc tcttggttgc aaactcactg tctcaacttt ttcatgaagt tccgtattgt
    11881 cttgaggctg tttgtctgat gtgtcaaccg attcggatac atcttcatct tccaacgcat
    11941 ccaaggggat ttcttcataa tcgctggcat caggatttga atttctcgct atcctaggca
    12001 aagctcgggt tgttgcatca gatgacagtt ccggtggtat agccctgcgg ttacgacgtt
    12061 tgggttgaga ttgtgctgct tggcgacctt cttcttccgc cttttgcttg gcaagttcgg
    12121 cggcttcacg ttcggcttcc gctttttgct cggcaatttc tgctgctttg cgttcagttt
    12181 ccgctttttg cttagcagcc aactctgcag cttttcgtgc ttcttcttgt tggcgtgcaa
    12241 gttcggcagc ttggcgtttt gcttcttcgg cttctgcttt ttgtttggca atttcggcag
    12301 cttggcgttc ggcttccaat cgttggcgtt cttgctctgc ttgttggcgg gcaagggcat
    12361 cttgctgacg tttcgcttct tcagcctttt gatgtgcgac tttttctgct tctgcttgct
    12421 gacgcttcac ttgctccgct tttgcttgtt ggcgttttgc ttcttcggct tgatttgcct
    12481 gcgggctagg cggtgcgacg acgatatttt gaggcttggc aatttgtgca ctgtccgttt
    12541 gtgcttgaga agccgtgttt gtggcaggag acggggccgg tttgactcgg cggcggttct
    12601 cggcataagg attgtacaat cgggtaatac cgttttctgt tttgattgta taacgcaatg
    12661 cgcctaaatc tacatggtta ttcgccaagg aaacagaaag gcgggagcgg tcttgtacgg
    12721 atgatgcatc aaagagatcc agcccttcct gattgggttc gcctgtttta tcttgaacat
    12781 ggagctgata atgaccggat gcggattcct tcacaagcac tttatcccca agatttttcg
    12841 ccaggtgcgt cagataatga aaatgcccgt taccggataa atgattgatt ttgagcgtgt
    12901 ggtatttatt tgcactttgc gcatcggaag cgttgttcaa atgaatatgg ctatccgcca
    12961 atgacagatt gtgtacttgg ctgtcgccgg tcaaatgcca tttgctatgt tgatttaggc
    13021 tgacgctgct gtttccttgc ccttgaattt gcccccataa tgcagccttg cctaagacca
    13081 atgccgcatt ctgattcaaa ttcacattgc cgttaatctg tgtcgcatca aagctgttta
    13141 aagccttatc ggataagttg tctgtgttgc aggtaacgta accggtatag tccgagcgca
    13201 cgcaaacttc atcgccgttt ttgtaaccca aatttacttt ggcgttgtct gttgcggtga
    13261 tgttggcggt gatgttggat acatttctac cggaagagaa tgatgcggat tgattaaccg
    13321 caatttctgt ggctttgaat gtgcggttta tccagtcgtc ttcaaatacg acttcattgt
    13381 ttttggagaa atgtgcgtct tttcgggctg aagatttgtt cacaaaatct cttgcgtgtg
    13441 gtgttggacg acctgataac aagacattgc cttgagttac gcttattttt ccgtttaaat
    13501 tagtgccgcc tgttaacaag aaacggtttt gcgcgctttt gccgttgaaa ttaaggttta
    13561 atgcaccgtt atgtcctttt ccgttttctt cgccaaagaa accgctaaaa ccgctaatac
    13621 gctgattgtt tttgtggttc atcgcgtttt tctgggcttc ttcttgctta tatcccataa
    13681 agacccagtc gttattttcc gtttgtccgt tttcgggcat cggtgcgttc acgctgccgc
    13741 cggattttag ggcgtaataa cggtagtttt tgaaataaag atctttgcct tgtggaatcg
    13801 gtttcctagg gcggtaatag taataaccat catcgtcatc atcattattt tgaatataat
    13861 gaatagagat ggttttggga tcggtaatca aagatttacc cgttagcgtg attgtggagg
    13921 cgtggcttgt gttgtggttg acaatgcgcg cgccttcatc cacgttgcgg atgtgttcaa
    13981 aagtcaagtc attgccattg gcatccaaac gaccgccacg gaaaccgaaa tataagttat
    14041 cgggattaat ctgatttgaa ctatttaata ccaatgtacc gcgtccgctc acaatgccga
    14101 cttgggagaa agcctggact tttttgtcgg catcggcttg ttgattcaga ataaccgtac
    14161 cgtcgccgac ttttaattgc ccttggttaa cgcctgtgcc gtttatttct aatgtgcctt
    14221 tgccgatttt tgccaatctg tcgccattcg gatttttgac ttgccaaacg acttttttgc
    14281 cgtcggcaac atcaatcccc gcacctagcc aagtgatgtc attatttgca cctttgactg
    14341 tgtaatcgcc tttgaaaaac agaccgcccg cgccttggtt gatgttttga tccaatacca
    14401 aagtgccgtt gtcttcaaag gtaacattct gtccgttgtt tgcatccctt tcattgttgg
    14461 caagccttac cgctgtcgaa ccgatatggc tgtttgtgcc cgtggttttc caatgatgtt
    14521 cgccataacc tttgatggtg ccggcgttat cgcgttgttt gattttatct gcaaattctt
    14581 ttttatagat attccattct tgccaagagt ttttttgata gcctgcccaa taatcgtaag
    14641 cacctaaaaa gacccagcgt ttttcttgtt tatcataagc aaataatggt gaaccgctat
    14701 cgcctaacac agcatagtta gtcaatgcgt tttgagataa aacttctttg agtttttctg
    14761 gggaatgatg ttttgaatta tcaccgaagc caatcaagcc ttcttgattt agattcgatg
    14821 tgacattcac gtcttgataa ggcgtacctg caatggcata acgataagct cgtgaaagct
    14881 ctgtcatatt gtagcggctg ttatattcaa attgcgtacc tgctccaact cgcacaaact
    14941 cagaaaaacg gtttttatct ttataggttt caacgccgcc gcctgcactg gttggtgcaa
    15001 taggtgcgac ttctgttacg aatttattaa ggcgtgccat gttgtagtct tcaagacgac
    15061 cttgattacc gtgatgccaa tttttatttg gttcgtagtc attttgtgca actgaacgat
    15121 attcgttttc atcattgcta acatctaagt gcccattgtg atgcccgtaa taagagattt
    15181 cgtctccttt tacatgtttg acgctgacgg catactgggg atcgatgacg gttaatgtac
    15241 gtctgttgac atctgcaacg ctaaaatcaa tcatcggtac gttggataat gcgttgccga
    15301 tgttttgacc ttgtttgttt ttcactgata aatcggttgc gccgacaaaa aatttgcctt
    15361 tgttttctgc aaagtcacgg aatatttgat aatcgacatc gtctctgacc aatgccgctt
    15421 ctgagtatgg cgtaagggca taggcaagaa agatggataa ggatatggcg ttaattttaa
    15481 aacgtttggt tttcataagg ttttaccgtt ttaagggtga taatgttttg tattttacgc
    15541 cggtttggcg gtgttgacta ttttttgttg tgtgaatcat taattttggt gttttattgc
    15601 caatttaaaa aaagaatccc gatgttttta tttccgcttc ctttgttctg ttattcaagc
    15661 gaaggcggga agccgatttt cggggttcgg ttcttccgtt aaatttctgc ggctttttgt
    15721 ttttggattc ccgcttttgc gggaatgacg ggattttagg tttctgattt tggttttctg
    15781 tttttgaggg aatgacggga tgtaggtttt cttaaccctg cgtcctagat tcccgctttc
    15841 gtggtaatga cgggatgtgg gttcgtggga atgacgcggt gcaggtttcc gtacggatgg
    15901 attcgtcatt cccgcgcagg cgggaatcca gaccttagaa caacagcaat attcaaagat
    15961 tatctgaaag tccgagattc tggattccca ctttcgtggg aatgacggga ttttaggttt
    16021 ctgattttgg ttttctgttt ttgtaggaat gatgaaattt tgagttttag gaatttatcg
    16081 ggagcaacag aaaccgctct gccgtcattc ccgcgcaggc gggaatctag accttagaac
    16141 aacagcaata ttcaaagatt atctgaaagt ccgagattct ggattcccac tttcgcggga
    16201 atgacgaaaa gtggtgggaa tgacgatgga aagtttgccg ttgtctcgga taatactgag
    16261 gcttttcgtt tgcattctta tagtggttta acaaaaacca gtacagcgtt gcctcgcctt
    16321 gtcgtactgc ttgtactgtc tgcggcttcg tcgccttgtc ctgatttaaa tttaaaccac
    16381 tatatcattt tcaaatcttg ttatgacggt ttttcggatt tgctttatta tccgtttatt
    16441 tttgaaatat ctggggtggg gagacgtgtt ccgtcgttgg tttttgccgt gttgggttgt
    16501 cggtgcggcg gcttcgttcg cgctgccggt cgtgccgcat tggctgtttt ggctggcggc
    16561 ttttgcggtt tttgctgtgt ttgcaaggcg ttttgcgttt gccggtctga tgctatgcgt
    16621 gttggcgggc gcggcttacg gcgtattcag aacggaagcg gcactgtctt cgcaatggcg
    16681 ggcagaagcc gtttcaggcg tgcctttgac ggtggaagtg gcggatatgc cgaggtcgga
    16741 cgggcggcgt gtgcagtttg cggcaaaggc tgtggacagc ggtggtcgga cgtttgattt
    16801 gctgctgtcg gactacaaac ggcgcgaatg ggcggtcggg agcagatggc ggataacggc
    16861 acgtgtgcac cccgtcgtcg gcgaattgaa cctgcgcggt ttgaaccgtg aggcgtgggc
    16921 attatccaac gggataggcg gcgcggggac ggtcggtgcg gacagggttt tgctgcatgg
    16981 cggaagcggt tggggggttg cggtttggcg cagccgcatc agccgtaatt ggcagcaggc
    17041 ggatgcggac ggcgggcttt cagacggcat cgggctgatg cgcgcgttga gcgtgggcga
    17101 acagtcggca ttgcgccccg aattgtggca ggcgttccgg ccgttggggc tgacgcatct
    17161 ggtcagtatt tcgggtttgc acgttacgat ggtggcggtg atgtttgcgt ggctggcgaa
    17221 gcggctgctt gcctgttccc cgcgccttcc tgcccggccg cgcgcgtggg ttttggcggc
    17281 ggggtgtgca ggcgcgctgt tttacgcgct gcttgccggt ttttccgtgc cgacgcagcg
    17341 cagcgttttg atgttggcgg cgtttgcgtg ggcttggcgc aggggaagat tgtcggcgtg
    17401 ggcgacgtgg tggcaggcgt tggcggcggt gctgctgttc gacccgtcgg cggtcttggg
    17461 tgtggggact tggctgtctt tcggtttggt ggcggccctg atatgggcgt gctcggggcg
    17521 tttgcacgag ggaaaacggc aaactgcttt gcgcgggcag tgggcggctt cggtgttgtc
    17581 gctggttttg ctcggttatc tgtttgcttc gctgccttta atcagccctt tggtcaatgc
    17641 ggtggcaatt ccgtggtttt cttgggtatt gacgccgctg gcgttgctgg gttcggtcgt
    17701 gccgtttgcg cctttgcaac agttgggggc atttttggcg gaatatactt tgcggttttt
    17761 ggtgtggctt gccgatgtgt cgcccgagtt tgccgttgcc tccgcacctt tgccgctgtt
    17821 ggtgttggcg gtgtgtgccg ctttgctgtt gctgctgccg cgcggcttgg gtttgcgtcc
    17881 gtgggcggtg ttgctgttgg cagggtttgt gttttaccgt tcacccggcg tgccggaaaa
    17941 tgaggttgcg gttacggttt gggatgcggg gcagggtttg tcggtgtcgg ttcagacggc
    18001 aaatcatcat cttttgtttg acaccggaac ggcagcggcg gcgcagatgg ggattgtgcc
    18061 gagtttgaat gcggcgggtg tccgccgttt ggacaagctg gttctgtcgc atcacgacag
    18121 cgaccacgac ggcggttttc aggcagtcgg caagataccg aacggcggga tttatgccgg
    18181 gcagccggaa ttttatgagg gggcgcggca ttgtgcggaa cagcgttggc aatgggacgg
    18241 cgtggatttt gagtttttga tgccgtctga acgcaaaaac atcgatgata atgggaaaag
    18301 ttgtgttttg cgtgttgtgg cgggcggtgc ggcactgctg gtaacgggcg atttggatac
    18361 gaagggcgag gaaagcctgg tcggcaagta tggaggcaac ctgtacagcc aggttttggt
    18421 tttgggacat cacggcagca atacgtcctc gtcgggcgtg ttcctcaatg ccgtctcgcc
    18481 cgaatatgcc gttgcttcaa gcggttatgc caacgcctac aaacatccga ccgaagcggt
    18541 gcagaaccgt gtccgcgcac acggcatcaa actgctgcgt accgatttgt cgggcgcact
    18601 gcaattcggc ttgggacgcg gcggcgtgaa ggctcaacgt ttgagagggt ataaattcta
    18661 ttggcagaaa aaaccgtttg aatgaggttt gaaacataaa atgccgtctg aaacggcttc
    18721 agacggcatt acgaagatgg gcttaatgcc agtaacgcca ccagggcata tcgtcgggct
    18781 gccaagcgtg cgtcaaaaac gggcttttcg ggaagttggt ttccaacacg cggcgcgtat
    18841 cggcggcaag ctgtggtttg ccgagttttt ggtaggcaag ttccaatatg gcgagcgatt
    18901 cttcgacata acgcgtattc tggtagctgc cgatgatttt ttgggcgcgg ttggcggcgg
    18961 cgatgtatgc accgcgtttc atgtagtagc gcgccaccga catttcattg ccgcccaaag
    19021 catcgaccag tttgatcatg cgtgcggtcg catcggcggc gtatttgctg ttcgggaagc
    19081 gttggacgag ttccgcaaac gcctgatacg cttcgcggtt ggctttcgga tcgcggtcgg
    19141 accagtcttg cgaggccagc ttgttcaaga aagactgatc ttcgttgaac agtaccaagc
    19201 cgcgcagata cagcgcgtaa tccatattcg gatgctgcgg atggaggcgg cggaagcgtt
    19261 cgattgccgc cagagccttg tctttttcat cgtctttata ataggcgtat gcggtatcca
    19321 gttgcgactg ccgggcatgg cggctggtgg ggaagcgcga ttccaagatt tcgtataact
    19381 tgacagcccg cgtataattg ctgctgttca attcgtcctg ggcttcggca tagagcttct
    19441 ccacactcca atcttgggta atctgggcat ctttatcgac cgtaccttga gtggcacagg
    19501 cactcagtgc caaacctaat gaaaccgtta aaagaatttt tttcatgcag aatacttcct
    19561 ttgataatga atccgattat agcgatgatt cagactttgt gtcagcttcc gaaactgaaa
    19621 accgtatcgg tctgaccgtt ccgctcgagc ttgccggcgg gcggttggat gcggtgttgg
    19681 cgaaacttct gcccgactac tcgcgcagcc gcctgacatc atggattaaa gaaggcgcgg
    19741 ttattgtaaa cgataaacct tcgcaaccca aagacaaaat gataggcggc gagcaaattt
    19801 gtgtaaccgt ccgtccgagt gaggaaaatc tggcgtttgt tccagagcct atggctttgg
    19861 atattgttta cgaagacgat accgtcatcg tcgtcaacaa accggccgga ctggtggtgc
    19921 atccggcggc gggcaactgg acggggacgc tgctcaacgg cctgttggcg cattgccccg
    19981 agctgtccca aattccgcgc gcgggcatcg tacaccgttt ggacaaagaa accagcgggc
    20041 tgatggtggt tgccaaaacc ctgccggcgc aaaattccct cgtgaggcag cttcaagagc
    20101 gcacggtcaa acgcatttac cgcgccgtcg ccaacggcat cgttcccttt gacggtaaaa
    20161 tcgaaaccca aatcggacgc gatccgcaca accgcctgaa aatggcagtc gtcaaattcg
    20221 gcggcaaacc agccgttacc cacgtcaaag tgttggaacg ctatcttgcc cacagctata
    20281 tcgaatgctc gctcgaaaca ggcaggacgc accaaatccg cgtccatatg cgtgaggcca
    20341 accatccgct tgccgccgac ccggtttacg gcaacccgcg ccatccgtgc ggcgacacgg
    20401 tgaaagaagc cgttaaaagt ttgggtgcgc gtcaggcatt gcacgcctac cgcttaagtt
    20461 tcactcatcc gaaaaccggc gaaaccgttt cgtttgaagc accgattcca aacgacatat
    20521 atcatttgtt atccgttctc cgtcttgaag ccggtttgga ttcgtctttg agcaatgaag
    20581 aggaatggca ggacaaattc ggcgcggacg acgatgacga ttggaacgaa gacgactacg
    20641 atgtcgaagt ggtttatgta agggagtgag gcggcttgaa aggcggggcg aacgcaggca
    20701 gccgaaccgg agcagccgga caatcgtccc tgccgatttc aaacaaaggc cgtctgaagg
    20761 ggtcgggcgg aaaccgccgg ttttgtttgc cccgttcaga cggcattatg atgaaaggcg
    20821 tttagggttt tttatgttta ccggctttgg ccgcccaata agttgccagc agcgagccgg
    20881 agatattgtg ccacacgctg aacaatgcgc ccggaacggc aacgaccggc gcagcggcaa
    20941 agtgtgcggc ggcaagcgcg gcggccaggc ccgagttttg cataccgact tcgatggcca
    21001 gcgttttttg tgcatcataa ggcaggccgg tccatttggc ggcaaagaag ccgagcaggt
    21061 agccgatgcc gttgtggagt acgacaaccg caaaaatcag caggccgctt tccataatct
    21121 tgcctttgct tgccccaaca accgcgccga taatcagcac gatggcggca acggaaacca
    21181 gcggcagcgc atcggtcagc ttttcggttt tactgcccaa aaccttatgg acaatcaaac
    21241 ccaaaacaat ggggagcaaa accattttga cgatggacat caacataccg gccgcttgga
    21301 tttccagcat ttcaccggca agcatcagga agatggcggg agtcagcaat ggggaaatca
    21361 gggtggaaac agacgtaacg gcaaccgaca aagccacatt gccgcgcgcc agataggtca
    21421 tcacattgga agccgtaccg cccgggcagc agccgaccaa aatcacgccg accgcgattt
    21481 cggcaggcag gttcaacagt ttggacagca gccaggcggt tgccggcata atggcgaatt
    21541 gtgcgattac gccgatgatg acggctttgg gatgtttgaa caaaatatcg aagtcggaag
    21601 gtttgagcgt caaacccata ccgaacataa taatgcccaa cagccaagga atataaggcc
    21661 ccgcccattt gaaagtgtcg ggcgcgaaaa aagcggcggc ggcaaagagc gcggcccaga
    21721 gggaaaatgt ttttccgata aagctgctga ttttactgag gatattcata ataatgcgtt
    21781 gcgtgtttgt ttttaaggga aggcaagcat acacgcctta accttaattt gcaaaatgac
    21841 cgcgcctaaa caatgccgtc tgaaagtgga gattggtttt cagacggcat cgcccgagag
    21901 atgtcggaaa tggactttat ccccattcct tttcggttga aacccatctg tttatagcga
    21961 tagaatctaa tcggagggta gtctcgttcg ggcaacacgc agtgcggtgc ttgatgtgcc
    22021 atcccctgtt gaaacatata gtggattaac aaaaatcagg acaaggcgac gaagccgtag
    22081 acagtacaat agtacggaac cgattcactt ggtgcttcag caccttagag aatcgttctc
    22141 tttgagctaa ggcgaggcaa cgccgtactg gtttttgtta atccactata taaagctcgg
    22201 agaaagtata taaggacatc attcctgcac cggcaagaat ccgaacccga acgtttgaaa
    22261 acaatcccga atctccgaat tcccgcctgt gtgggaatga cgaaaaaaca agcattcatt
    22321 tgccccgaag gcagttaatc aaccctttcc gccacacacc tattccaata tccaatgaaa
    22381 accatcacag aaaccctaaa tctcgccccg aaaggcaaaa acttcctgac cgccgattgg
    22441 cccgcgcccg ccaatgtgaa aaccctgatt accacgcgca acggcggcgt gagccaaggt
    22501 gcgtatcaga gtttgaacct cggtacgcac gtcggcgaca atcccgaagc cgtgcgccgc
    22561 aaccgcgaaa tcgtgcaaca gcaggtcgga ctgcccgttg cctacctcaa tcaaatccac
    22621 agtaccgtcg tcgtcaatgc tgccgaagcg ttgggaggca cacccgatgc ggacgcttcc
    22681 gtagacgaca cgggcaaggt tgcctgtgcc gtgatgaccg cagactgtct gcctgttttg
    22741 ttttgcgaca gggcgggtac ggcggttgcc gccgcacacg cgggctggcg cggtttagcg
    22801 ggcggcgtat tgcaaaacac cattgctgcg atgaaggttc cgcctgtcga aatgatggcg
    22861 tatctcggcc ccgccatcag tgcggatgcg tttgaagtcg gacaggatgt gtttgatgcg
    22921 ttctgcacgc ccatgcccga agccgccgcc gcatttgaag gcataggcgg cggcaaattc
    22981 cttgccgacc tttacgcgct cgcccgcctg attctgaagc gtgaaggcgt gggcggcgta
    23041 tatggcggca cgcattgtac ggttttggaa cgggacactt tcttttccta ccgccgcgac
    23101 ggagcgacag ggcgtatggc gagcctgatt tggctggacg gcaatgccgt ctgaacacgc
    23161 cgctgatata atctaccgac tttgtgcttt tgagaaaggc aagccatgaa caaactgttt
    23221 cttactgccg cagtgctgat gctgggcgcg tgcggtttcc acctgaaagg tgcagacggc
    23281 atttctccgc cgctgaccta ccggagctgg cacatcgaag gcggacaggc attgcagttt
    23341 cctttggaaa ccgcgctgta tcaggcttcg ggcagggtgg acgatgctgc cggcgcgcag
    23401 atgaccctgc gtatagacag cgtttcccaa aacaaggaaa cctacaccgt tacccgtgcg
    23461 gcagtcatca acgaatatct tttgatattg acggttgaag cgcaggtatt gaaacgcggc
    23521 gagccggtcg gcaaaccgat gatcgtgtcc gtccgccgcg tccttgctta tgccgacaac
    23581 gagatcttgg gcaaacagga agaggaagcg gcattgtggg cggaaatgcg gcaggatgcc
    23641 gccgaacaga ttgtccgccg cctgaccttt ctgaaggcgg aatgacgtgg cggcacatat
    23701 cggacgcatt gatacggacg cgcctttgaa acccctgtac gtcatccacg gcgaggaaga
    23761 actgttgcgt atcgaggcat tggacgcatt gagggcggcg gcgaagaaac aaggttacct
    23821 taatcgggaa gtttatacgg cagacaatgc cttcgattgg aacgaactgt tgcaaaccgc
    23881 aggcagtgcg ggtctgtttg ccgatttgaa gctgttggaa ctgcatatcc ctaacggcaa
    23941 gcccggcaaa accggcggcg aggcgttgca ggattttgcc gcccgcctgc cggaagatac
    24001 ggtaacgctg gttttgctgc ccaaactgga gaaaacccag ctccagtcca aatggtttgc
    24061 cgcattggcg gcaaaggggg aagtgtggga agccaaaccg gtcggcgcgg cggccttgcc
    24121 ccaatggata cgcggacggc tggacaaaat cggtttgggt atcgaggcag acgcattggc
    24181 actgtttgcc gagcgcgtgg aaggcaattt gttggcggcg cgtcaggaaa tcgacaagct
    24241 cgcgctgctg tatccgaaag ggcataccgt caatatcgat gaggcgcaaa ccgccgttgc
    24301 caatgttgcc cgctttgacg tttttcagct tgccggcgca tggatgaagg gcgatgtccc
    24361 gcgcgtatgc aggttgttgg acggattgcg ggaagagggc gaagaaccgg tgctgttgct
    24421 gtgggcggtt gccgaagaca tcaggacgct gatccgtctg gctgcttcct tgaaacaggg
    24481 gcagagtgtc caatccgtac gcaacagtct cagactttgg ggtgaaaagc agacgctcgc
    24541 accgcttgca gtcaagcgga tttccgtcgt ccgcctgctt gacgcgctca aaacctgcgc
    24601 ccaaatcgac cgaatcatca aaggtgcgga agacggcgac gcatggacgg tattcaaacg
    24661 gcttgtcgtg tcgctggcgg aataaagcgg taatccccaa aatccgaaaa tactgtaaaa
    24721 taccgttaat cctgaaaagt attcaccaat ccgtccgaaa acatttcaga cggcacgacc
    24781 acctcaataa aggaacatta accctatgga caataagacc aaactgcgct tgggcggcct
    24841 gattttactg actaccgccg ttttaagcct cattatcgta ttgattgtcg actcctggcc
    24901 gcttgccatc ctgcttgccg ccgtcatcgt cgccgccgct gcgggcggtt ttgtttggac
    24961 atcccgccga cagcaacgcc agtttatcga acgcctgaaa aaattcgaca tcgatcccga
    25021 aaaaggcaga atcaacgagg caaacctgcg ccgtatgtac cacagcggcg gacaacacca
    25081 gaaagatgcg attaccctga tctgcctgtc gcaaaaatgt tcggtggacg aggcgcacgc
    25141 tatgttcaaa aaacgcccga cacgtcagga aatcaatcaa atggcggcaa aacagtcgcg
    25201 cggtcagaaa cgtccgcacc gttaaccgcc gcaaggcatc tttgcataaa tgccgtctga
    25261 agcctgttgg cgtttcagac ggcatattct gattgaaaag atgatgacac tgaaaaccgc
    25321 cccgctcaaa cgccgctttg ccgccatgct gtacgaaatg ctgctggtcg gtgcggcaac
    25381 ctgtttggca gcattgtttg ccggtattgc cgccattttt ctgaatcccg tttctatcgc
    25441 ggtttctgca ttggtaacga gtatcctgat aatgggatca tggtggcttt attttcgcgc
    25501 caactggcac ggtcaggggc agaccttggc gatgaggaca tggaaaatcg gcttgtgcga
    25561 ccttaacggc atacagccgt ctttgtacct gttgcgcctg cgctttattt gggcgtgcat
    25621 attcatcgtc ttcattccta tgcttgctta tgccggattg cgccacttcc tcggcattcc
    25681 gcccaagggc gcggccggcg cggcattgat ttggctgatt ttaccgtggg ggttcgcact
    25741 gctgaatccc gaccggcagt ttctgtatga ttttcttgca ggaacaagat tggtggcggt
    25801 caaaggaaag ccttaagcct ttataccgca aaggtttcaa cctgaaaaaa tgccgtctga
    25861 aagggctttc agacggcatt tgcttatcgg ggaaaccgat tattcgatat tctgcacctg
    25921 ttcgcgcatc tgttcgatca ggactttcag ctcgaccgag gcttgggtgc attcggtagc
    25981 gatggatttg ctgcccaaag tgttggcttc gcggtttaat tcctgcatca ggaagtccag
    26041 ccgtttgccg ctgctgcctt tgtgttcggt aacgatacgg cgcacttcgg caatgtgggt
    26101 gcgtaggcgg ctgaactctt cgtcgatgtc ggatttttgg ataaagaggg caaattcctg
    26161 ttgcaggcgg tcgttgtcga tgctgccgac cgcttcggca aggcgggcgc ggattttttc
    26221 tttatgtgtt tccaacaggg taggaaagag ttcgcttaat gcatctatga tttcttccat
    26281 gctttcgagg cgttgtaaca ggtgctcgcc caattttttc ccttcgcgcc ggcgtgcggc
    26341 ggtaaagtcc ttcagtgccg aatcggtcaa atcggcaata acctttgcca atgcgtccgc
    26401 attttccctt tgacttgcca atacgcccgg aaagcgcaaa atatcggcaa cgcccagttt
    26461 tgccaaatca taatgcttgc ggaggtcttt gttgatttcg gcaagctgtc cgaccagatc
    26521 gcgattcagt tccaaagact gattgccgtt ttccgcatct tgaatttgga ttttgcattc
    26581 gactttgccg cgtgcgatat gggatgaaat tttctcgcgg ataccgcttt ccaaatagcg
    26641 caaatcgtcg ggcatcctga tttgaatatc tagaaaacgg tggttgaccg cacgcaggtc
    26701 gagattgatg cgtttgctgc cgcactctgc cgctgcgttg gcaaatccgg tcatgctgtg
    26761 gatgtggata tttccgctgc tcatgtcgtt ctccgaagcc cgttaaaatg gaatcaatat
    26821 atcacatctg tatggcggca agcgttttcg ggtgtgaaaa attgaagatt ttgcagcggc
    26881 agattggaat cacgcgcttt tgttgctgca aggaagggaa atgtatagtg gattaaccaa
    26941 gaccagtacg gcgttgcctc gccttagctc aaagagaacg attctctaag gtgctgaagc
    27001 accaagtgaa tcggttccgt acgatttgta ctgtctgcgg cttcgccgcc ttgtcctgat
    27061 ttttgttaat ccactatatc aattccgcca atctgtcgga aaagcagctg atgcggcagt
    27121 gtctggtgca tgtctgcttt ttgatttcgg caattgcaac ggcgtggacg gataaaatcg
    27181 tgtacagcac gacgcacaaa ccgcattgat gtttaccaaa taaaataccc gacaaaacaa
    27241 tttgtcgggt attttattgc gtatatttca aaccgcttcg gcttcttcgg tcaggaaacc
    27301 acgcagtttc tgcatggctt ttgcttcaat ctggcggatg cgctcggcag agacgccgta
    27361 ttctgcagca agctggtgca gcgtcagccc gccgtcgtct tgaagccagc ggctttccac
    27421 aatacggcgg ctcctgtcat ccagttgcgc caaagcgttt tgtaaacctt ctgtttgcag
    27481 ggcgtaatgc gcctgtttcg atagttgccg gctcggttcg gaatcgtggt cggcaagcca
    27541 gtcgatgggg gcgaaactgt cctcgtcgtc gctgttgtct gccatgatgg cgatgtcgtg
    27601 tcccgtcatg cgctgttcca tttccagaac ttcggaaagt ttgacaccca aatcgtcggc
    27661 gatgtcttgt gcctctttgg gagacagggc gttgaggttt ttacgcatac tgcgtaaatt
    27721 gaaaaacagc ttgcgttgcg gtttggtggt ggcaacgcga accaaacgcc agtttctcaa
    27781 aataaactcg tggatttcgg ctttaatcca gtgtacggca aatgaaaaca gacgcgcgcc
    27841 tctaccgggc tcgtagcgtt tgaccgcctt catcagtccg atattgcctt cctgaatcag
    27901 gtctgcctga ttcagcccgt agccgtcata gccgcgcgcg atggaaacga cgacgcgcag
    27961 gtgggacagg atgagttgtt tggcggcgtt gaggtcgccc tttatccggc gttcggcgag
    28021 gcgggtttct tcttcctggg acagcatcgg gatgctgttg acggtgtgga tgtattgttc
    28081 gaggctgccg ttgccgcttt ggatggcggg taatgcgaaa gcgttattca tttggggcat
    28141 ttcctttcgg ctgaaactgc gtatcggcgg tttgctgtgt tgggatgcag tatatcactg
    28201 cttggcttgt attttgtatg tttggcagga gatatgcgct aaggtttgaa agacaggaaa
    28261 attttgtaag gcaggtttga ttgattttgt aaacctgatg actcaattcg atttcagaat
    28321 tatattacat acgtagttgt atgtaaacgg ccggtttgaa aaaagacagc ccgtccggac
    28381 gggctgtgca ggtatcagtg ttctttgttt cggaagatga aaagaatcag tgcggctagg
    28441 gtcaatatgc ccatcaacca ccatgaactg ccggttttca tatagggcgt ttcgccgaca
    28501 tagcctttga tgtgtccttc caatacggtt tccgtatcgg gttgggcttg ggcgatgatg
    28561 ttgcctttgg gggagatgat ggcggttgcg ccggtgttgg tggcacggac catatagcgt
    28621 ccgagttcca tagcccgcgc ctgcgattgt tggaggtgct ggtacatggc gttggatttt
    28681 ccgtaccacg ccatattgct ggcattggca agcagggtgg catctttggc ggcggcaatc
    28741 agttcgtcgc cgaatccgtc ttcgtaacag atgttgaagg cgattttttg gtttttcatc
    28801 agcagggcgg attgcttacc gccgcctttg cggaagtcgg aaaggggcat attcatcatt
    28861 ttgtaaagcg gcgtggtcag gaagggcagc ggtttgtatt cgccgaaggg gacgaggtgg
    28921 tttttggcgt agtaggggat gccgtcctga ttgttttcct gataaccggt caggttgatg
    28981 acggcgtttt cgtaaccgtt gccgtccgaa gtgtattggc tgatgccgac ggcgagcgcg
    29041 ctgccgttgt tttgcgcctg ttcggcaaat tttgccagta tgttttccgg caggttttgg
    29101 cgcataacgg ggatggcggt ttcgggcagg atgacgatgt cggcagtggt tttgccgacc
    29161 tgttcgtaat atttctgtat ggtcgggatg acttggtctt cacgccattt gagggtttgg
    29221 tcgatgttgc cttgaagcag ggcgacggtg ctgcggctgc cgtcggggcg ggtgaagtcg
    29281 gtttgtcggg cggtgtagcc tgcggcaagc agggcggcaa tcaggataat tggaagcagg
    29341 cgtttgcccg aacgtgcggt gttatcactc gccaaaacca gccagacacc gagaaaggcg
    29401 gttgccagtg taaccatgtg gatgccgccc aatggggcaa agccggcgag cgggctgtcc
    29461 ggggtgattt gggagtagcc gattgcgccc cagccgaatc cggtcaggaa acgttcgcgg
    29521 gcaaactcgg tcagtgtcca caggatgggc agtaccaaac cgatttttat gccccgaggc
    29581 agggtaaatt ttttccacag ccagaaacac agtgccggat aaagggcaag gtaggcgggg
    29641 agtaggaaag tcagcggtac ggcatagagg tcgggcaggc cggaaacgtc gtgcagggcg
    29701 gtgtgtatcc agtagaactg tgtcgtgtat gcggtcaggc tgaacaggta ggcggaagag
    29761 acagcaaaac gcggacgcag ttcgatgagg cggacgaagg caccgaaaat caagggcatc
    29821 agccaaaagt ggtagtaggg tgcgaaggta aagggggtgg cggcggcaaa aaggatgagc
    29881 aaaggccagt agagggcggg gtgctgccag tatttgtcca gtttggaaaa catattcatc
    29941 tgtctgttcg gaagataccg tctgaacatc tttcaaacgg catcggtatt tgaaaaagaa
    30001 atcaatgcct gccgaaacga ttcatcagcg gcaaggcggg ggcgcaggca atcgaaccgg
    30061 aaagcagccc gacaacgagg ttggcgaagt actccgccca gccagcgtcc cagtgttgcg
    30121 cgtgcaggaa atcgtgcaga aggccgaggt tgtgggcgac cagtacgccg ccgacaagaa
    30181 acatggcaag cgtgccgacc acgctcaaac cgcgcataaa gcaaggcata aaggcagtca
    30241 gcatttgccc caaactgcgc gaaaaggttt gtgggcggcg catcagcagc atgcctaagt
    30301 tgtcgagttt gacgatgacg gcaacgattc cgtacaccaa aacagtcatg ccgatgccga
    30361 ttgccgccat tacgagcatg cgcgtcatgt cggtgcagaa acttgtgcag cagcttttct
    30421 acgccgtcaa agcacagata aatgccgcct gccgtcaaaa gcggcgtaat gagttgcggc
    30481 aggaaggcgg aaagcagcag ggccgcaggc accaaaaccg gcttgttgga aaaagaacct
    30541 ttcgccatcg accaaacaat cggcaactcg cgttctgccg atacgcccgt aacccggttg
    30601 gcattgggtg ccaaatcgtc gccgaccacg ccggcggttt tctttgcggc ggctttggtc
    30661 atcagggcaa catcgtccaa aacggcggtg atgtcgtccg gcagggtaaa tagtgaggca
    30721 aatgccatta aagaatcctg aaatgcggcg caaagtccga cattatatag gagaacgcgg
    30781 atttgggcgg tttcaggcgg catgaaacag gaaaatgccg tctgaacgct gtggcggacg
    30841 tgaagtaaag tttcgtgaaa agaaaatgcc gtgttacagt ctttcgattt taatttcatg
    30901 aattttaagg gagaatcgtt agcgtggatt ggatgggcag tctgttcctg ccgggtggcg
    30961 cactgttgtt tctgagcgtg gtttcgacca ctttacccgc acgtttggga atgcctttgc
    31021 tgctggtttc tcccgccggc gtgttggacg gggcggcgga agccttggcg attgcggcgt
    31081 tcctgatgct ggtcgcgcgt ccgccggcag tgttcggcgg tttgtggaaa ttcaattaca
    31141 gcctgcgtga aaaggcgtat agccgaatcg aaatgcagtc cgacaccgtg cttcaggcgg
    31201 ggatttggcg tggtacatcc tgcccgacgg caaggtcgat atagtg
//
LOCUS       DAXIDM010000011        30395 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000011 DAXIDM010000000
VERSION     DAXIDM010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 30395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30395
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.011"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            80..1045
                     /locus_tag="ACFOAE_000417"
     CDS             80..1045
                     /locus_tag="ACFOAE_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6883976.1"
                     /translation="MLRLTALAVCTALALGACSPQNSDSAPQAKEQAVSAAQSESASV
                     TVKTARGDVQIPQNPERIAVYDLGMLDTLNKLGVKTGLSVDKNRLPYLEEYFKTTKPA
                     GTLFEPDYETLNAYKPQLIIIGSRAAKAFDKLNEIAPTIEMTADTANLKESAKERIDA
                     LAQIFGKQAEADKLKAEIDASFEAAKTAAQGKGKGLVILVNGGKMSAFGPSSRLGGWL
                     HKDIGVPAVDEAIKEGSHGQPVSFEYLKEKNPDWLFVLDRSAAIGEEGQAAKDVLDNP
                     LVAETTAWKKGQVVYLVPETYLAAGGAQELLNASKQVADAFNAAK"
     gene            1063..1212
                     /locus_tag="ACFOAE_000418"
     CDS             1063..1212
                     /locus_tag="ACFOAE_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883977.1"
                     /translation="MPSETRMQTASCVSDGIARYGGFKQGFPLRRFGLPCLNLLRRNA
                     FPFCL"
     gene            1209..2177
                     /locus_tag="ACFOAE_000419"
     CDS             1209..2177
                     /locus_tag="ACFOAE_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC6883978.1"
                     /translation="MTAKPFSLNLTNLLLLAVLFAVSLSVGVADFRWSDVFSLSDSQQ
                     VMFISRLPRTFAIVLTGASMAVAGMIMQILMRNRFVEPSMAGASQSAALGLLLMSLLL
                     PAAPLPVKMSVAAVAALIGMLVFMMLIRRLPPTAQLMVPLVGIIFGGVIEAVATFVAY
                     EFEMLQMLGVWQQGDFSSVLLGRYELLWITGGLAVFAYLIADRLTILGLGETVSVNLG
                     LNRTAVLWSGLIIVALITSLVIVTVGNIPFVGLVVPNIISRLIGDKLRQSLPAVALLG
                     ASLVLLCDIIGRVIVFPFEIPVSTVFGVLGTALFLWLLLRKPAHAV"
     gene            2167..3141
                     /locus_tag="ACFOAE_000420"
     CDS             2167..3141
                     /locus_tag="ACFOAE_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFC6883979.1"
                     /translation="MPSEKNIGFMAGSSRPLWVAFALLLVSCILFMTLNVKGDWDFVL
                     HLRLTKLAALLMVAYAVGVSTQLFQTLTNNPILTPSILGFDSLYVFLQTLLVFTFGGV
                     GYASLPLTGKFGFELVVMMGGSLLLFYTLIKQGGRDLSRMILIGVIFGILFRSLSSLL
                     SRMIDPEEFTAAQANMFAGFNTVHSELLGIGALILLVSAAVVWRERYRLDVHLLGRDQ
                     AVNLGISYTRNTLWILLWIAALVATATAVVGPVSFFGLLAASLANHFSPSVRHSVRLP
                     MTVCVGGILLVGGQTVFEHFLGMKAVLSVVVEFAGGLVFLYLVLKHKK"
     gene            3186..3812
                     /locus_tag="ACFOAE_000421"
     CDS             3186..3812
                     /locus_tag="ACFOAE_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FmdE family protein"
                     /protein_id="HFC6883980.1"
                     /translation="MTQERFPSFFNQAPTITVRDPLAAFLGAAENGILTYRYADAVRL
                     CGHSCPTVAGAYLMVIKGLKALYGEELPERGSIEAAMQGARDEGTVGVTASVVQLLTG
                     AAPETGFGGIGIQGRFARRNLLSFGAGEINGTLTLRRKDNGKTVAVSLNAAPKPFAPE
                     MRELMPKAVGGSASAEELERFGQLWQARVKAFLTESADDPQFVIVREV"
     gene            3896..4654
                     /locus_tag="ACFOAE_000422"
     CDS             3896..4654
                     /locus_tag="ACFOAE_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC6883981.1"
                     /translation="MITIRNVSYRIGTRPILDNVSLDIPEGGITALVGPNGAGKSTLF
                     SFMARLRPLESGSIAYRGKNLADTPTAELAKTLSILTQENSIMSRITVRDLLMFGRYP
                     YHQGRPTAECRRIVNGAIEEFHLQDLSDRYLTELSGGQRQRAMIAMVFCQSTDYVLLD
                     EPLNNLDMYHARSLMQILQKLTREHKRTTVAVLHDINQAAAYADHVVAMKNGKAVLTG
                     TPEEVFTVHNIKELFDMDVDVLDYEGKKLIVHHI"
     gene            4958..5929
                     /locus_tag="ACFOAE_000423"
     CDS             4958..5929
                     /locus_tag="ACFOAE_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YadA C-terminal domain-containing protein"
                     /protein_id="HFC6883982.1"
                     /translation="MKHFPSKVLTAAILAALSGSAMADNAPTADEIAKAALVNSYNNT
                     QDINGFTVGDTIYDIKNDKITKKEATEADVEADDFKGLGLKEVVAQHDQSLADLTETV
                     NENSEALVKTAAVVNDISADVKANTAAIGENKAAIATKADKTELDKVSGKVTENETAI
                     GKKANSADVYTKAEVYTKQESDNRFVKISDGIGNLNTTANGLETRLAAAEQSVADHGT
                     RLASAEKSITEHGTRLNGLDRTVSDLRKETRQGLAEQAALSGLFQPYNVGRFNVTAAV
                     GGYKSESAVAIGTGFRFTENFAAKAGVAVGTSSGSSAAYHVGVNYEW"
     gene            complement(5995..6333)
                     /locus_tag="ACFOAE_000424"
     CDS             complement(5995..6333)
                     /locus_tag="ACFOAE_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFC6883983.1"
                     /translation="MKKIEAIVKPFKLDDVREALTEIGITGMTVSEVKGFGRQKGHTE
                     IYRGAEYAVDFLPKVKIELVLADDAVERAIDVIVEVARSGKIGDGKIFVLPVEEAIRI
                     RTGERSDAAV"
     gene            6484..10446
                     /gene="purL"
                     /locus_tag="ACFOAE_000425"
     CDS             6484..10446
                     /gene="purL"
                     /locus_tag="ACFOAE_000425"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HFC6883984.1"
                     /translation="MSVVLPLRGVTALSDFRVEKLLQKAAALGLPEVKLSSEFWYFAG
                     SEKALDAATVEKLQALLAAQSVEQTPKAREGLHLFLVTPRLGTISPWASKATNIAENC
                     GLAGIERIERGMAVWLEGALTDEQKRQWAALLHDRMTESVLPDFQTASKLFHHLESET
                     FSTVDVLGGGKEALVKANTEMGLALSADEIDYLVENYQALQRNPSDVELMMFAQANSE
                     HCRHKIFNADFILNGEKQPKSLFGMIRDTHNAHPEGTVVAYKDNSSVIEGAKIERFYP
                     NAAENQGYRFHEEDTHIIMKVETHNHPTAIAPFAGAATGAGGEIRDEGATGKGSRPKA
                     GLTGFTVSNLNIPDLKQPWEQDYGKPEHISSPLDIMIEGPIGGAAFNNEFGRPNLLGY
                     FRTFEEKFDGQVRGYHKPIMIAGGLGSIQAQQTHKDEIPEGALLIQLGGPGMLIGLGG
                     GAASSMDTGTNDASLDFNSVQRGNPEIERRAQEVIDRCWQLGDKNPIISIHDVGAGGL
                     SNAFPELVNDAGRGAVFELREVPLEEHGLTPLQIWCNESQERYVLSILEKDLDTFRAI
                     CERERCPFAVVGTATDDGHLKVRDDLFANNPVDLPLNVLLGKLPKTTRTDKTVTPSKK
                     PFHADDIDITEAAYRVLHLPAVAAKNFLITIGDRSVGGMTHRDQMVGKYQTPVADCAV
                     TMMGFNTYRGEAMSMGEKPTVALFDAPASGRMCVGEAITNIAAVNIGDIGNIKLSANW
                     MAACGNEGEDEKLYRTVEAVSKACQALDLSIPVGKDSLSMKTVWQDGEEKKSVVSPLS
                     LIISAFAPVKDVRKTVTPELKNVEDSVLLFIDLGFGKARMGGSAFGQVYNNMSGDAPD
                     LDDTSRLKAFYNVIQQLVAEDKLLAYHDRSDGGLFAVLVEMAFAGRCGLDIDLNLLLA
                     QTFITNHTALSQSLRTEEVKALAEWQETIARTLFNEELGAVIQVRKQDVADIINLFYQ
                     QQLHHNVFEIGTLTDENTLIIRDGQTHLISDNLIKLQQTWQETSHQIQRLRDNPACAD
                     SEFALIGDNDRSALFADVKFDVNEDIAAPFVNSGAKPKIAILREQGVNGQIEMAAAFT
                     RAGFDAYDVHMSDLMAGRFRLADFKMLAACGGFSYGDVLGAGEGWAKSILFHPALRDQ
                     FAAFFADPDTLTLGVCNGCQMVSNLAEIIPGAEAWPKFKRNLSEQFEARLSMVHVPKS
                     ASLILNEMQGSSLPVVVSHGEGRADFALHGGNISADLGIALQYVDGQNQITQTYPLNP
                     NGSPQGIAGVTNADGRVTIMMPHPERVYRAAQMSWKPEDWTELSGWYRLFAGARKALG
                     "
     gene            10541..11293
                     /gene="gloB"
                     /locus_tag="ACFOAE_000426"
     CDS             10541..11293
                     /gene="gloB"
                     /locus_tag="ACFOAE_000426"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004416 - hydroxyacylglutathione hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019243 - methylglyoxal catabolic process
                     to D-lactate via S-lactoyl-glutathione [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HFC6883985.1"
                     /translation="MKITPVKALTDNYIWMIQHGNHAVCVDPSEPSPVLEFLVRNRLM
                     LAQTWVTHPHPDHEGGAAALWRGYMESPVYGESDIEAATHTVTAGTQFTFGDGQVTVW
                     ATPGHTDRHTSYLLETSDGIHVFCGDTLFSAGCGRVFTGTIEQLYDSFQRFNRLPENT
                     LFYPAHEYTAANLDFAAHIEPDNADIQAALKAAERTPTLPVTLAHERRVNPFLRTEIP
                     AVRQRAEALVGKTLNSGLEVFAALRELKNAYR"
     gene            11527..12981
                     /gene="mgtE"
                     /locus_tag="ACFOAE_000427"
     CDS             11527..12981
                     /gene="mgtE"
                     /locus_tag="ACFOAE_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFC6883986.1"
                     /translation="MSIEPTPPNLENDGIENDVERVSADFDRVHSLCEILEPAFEQIE
                     NGTPLEDAPLRDKLTELTVLLSELHPADVAAVLESLPPRERNIVWILVKPEDDGEVLL
                     EVSDAVRETLIESMDKDELLAAVDDLDADELAELADDLPHQVVYEALQTRDEEERAQV
                     KAAMSYEDNQVGAIMDFELVSIRADVACEVVLRYLRRFDSLPDHTDKIFVVDENDVLQ
                     GVLPIRKLLVADPEDLVENVMAKDVVRFRAEDDVEEAAQAFERYDLVTAPVVDENKKL
                     IGRITVDEMVDVIREESEADMLNMAGLQEEEDLFAPVLDSVKNRWMWLAVNLCTAFLA
                     SRVIGAFESSIEKIVALAALMPIVAGIGGNSGNQTITMIVRAMAMGQLTDMQAGRLLK
                     KEVSVALVNGIIWGAVMGAVSWLLYGSLGIGLVMIAAMTLNLLLAATVGVLIPVVMEK
                     FGRDPALGSSVLITAVTDSGGFLIFLGLATLFLL"
     gene            complement(13067..13975)
                     /gene="hslO"
                     /locus_tag="ACFOAE_000428"
     CDS             complement(13067..13975)
                     /gene="hslO"
                     /locus_tag="ACFOAE_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFC6883987.1"
                     /translation="MNQTAINRADVRTRFIFDDMPVRGLHVRLENVWQHIVKQKNYPA
                     AIRRALGELLAAGVLLSGNLKNEGTLIVQVQGQGRLKMLVAEATSDRTVRATARWDEA
                     AEIGEDESLVDLLGEGGVFVLTLQPKDGEPWQGVVPLEGDGIAQMLMNYMKRSEQLDT
                     HIVLSASDEAAGGLLVQRLPEEVLDEEAWEHVSTLARTLTAEELAELDAQHVLYRLFH
                     ETPPRVFEPETFEFSCTCSRGKVSDMLLMLGGEEVGGVVVEQGSIEVDCDFCHSKYVF
                     DETDVNVLFGEDVVGVAKGLPRHTVQ"
     gene            14220..14975
                     /locus_tag="ACFOAE_000429"
     CDS             14220..14975
                     /locus_tag="ACFOAE_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFC6883988.1"
                     /translation="MDSFFKPAVWAVLWLMFAVRPALADELTNLLSSREQILRQFAED
                     EQPVLPINRAPARRAGNADELIGSAMGLNEQPVLPVNRVPARRAGNADELIGNAMGLN
                     EQPVLPVNRAPARRAGNADELIGNAMGLLGIAYRYGGTSVSTGFDCSGFMQHIFKRAM
                     GINLPRTSAEQARMGTPVARSELQPGDMVFFRTLGGSRISHVGLYIGNNRFIHAPRTG
                     KNIEITSLSHKYWSGKYAFARRVKKNDPSRFLN"
     gene            14994..15212
                     /locus_tag="ACFOAE_000430"
     CDS             14994..15212
                     /locus_tag="ACFOAE_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6883989.1"
                     /translation="MSMPEMPKWYDDDGQIVSCTEKVKVMSENMAELYQTAQDAFEDA
                     LLMGCGERQLRDYLLALIEGLENPYRKV"
     gene            15357..15701
                     /locus_tag="ACFOAE_000431"
     CDS             15357..15701
                     /locus_tag="ACFOAE_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFC6883990.1"
                     /translation="MNIIRALLIILGCLATGETAVFLAGIKLPGSIVGMGVLFALLQA
                     GWVKTSWLQQLTDALMANLTLFLVPPCVAVISYLDLIADDWFSILVSASASTLCVLLI
                     TGKVHRWIRSII"
     gene            15701..16393
                     /locus_tag="ACFOAE_000432"
     CDS             15701..16393
                     /locus_tag="ACFOAE_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFC6883991.1"
                     /translation="MNEILRQPSVLLFLTLAVYALAIIVRTRTGNIFCNPVLVSTVVL
                     IAYLKILGIDYAVYHNAAQFIDFWLKPAVVVLAVPLYQNRRKIFNQWLPVIVSQLAGS
                     VTGIVTGMYFAKWLGAEREVVLSLASKSVTNPIAIEITRSIGGIPAITAATVIIAGLV
                     GQIAGYKMLKNTVVMPSSVGMSLGTASHAMGIAASLERSRRMAAYAGLGLTFNGVLTA
                     LIAPLLIPVLGF"
     gene            16460..17680
                     /gene="argJ"
                     /locus_tag="ACFOAE_000433"
     CDS             16460..17680
                     /gene="argJ"
                     /locus_tag="ACFOAE_000433"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HFC6883992.1"
                     /translation="MAVNLTEKTAEQLPDIDGIALYTAQAGVKKPGHTDLTLIAVAAG
                     STVGAVFTTNRFCAAPVHIAKSHLFDEDGVRALIINTGNANAGTGAQGRIDALAVCAA
                     AARQIGCKPNQVLPFSTGVILEPLPADKIIAALPKMQPAFWNEAARAIMTTDTVPKAA
                     SREGKVGDKHTVRATGIAKGSGMIHPNMATMLSFIATDAKVSQPVLQLMTQEIADETF
                     NTITVDGDTSTNDSFVIIASGKNSQSEIDNIADPRYAQLKELLCSLALELAQAIVRDG
                     EGATKFITVRVENAKTRDEARQAAYAVARSPLVKTAFFASDPNLGRLLAAIGYAGVVD
                     LDTDLVEMYLDDILVAEHGGRAASYTEAQGQAVMSKAEITVRIKLHRGQAAATVYTCD
                     LSHGYVSINADYRS"
     gene            17740..19149
                     /locus_tag="ACFOAE_000434"
     CDS             17740..19149
                     /locus_tag="ACFOAE_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFC6883993.1"
                     /translation="MTSTFPRRLARKIRQTRRLSRKSIAFLFLLAGSALVALTALFFA
                     HLADFALELNAKLVQQYPWFAWVALPLGLPLIAWLTRKFAPFTAGSGIPQVIASLSLP
                     YGAQKTRLIRLGQTLLKIPLTFLGMLFGASIGREGPSVQVGAAVMGAWGAWCKKHGLA
                     FKGMQENDLMAAGAAGGLAAAFNAPLAGVIFAIEELGRGIMLRWERQILLGVLASGFI
                     QVAIQGNNPYFSGFNGGVLEHIFLWVALSGLVCGAAGGLFGRLLYRGAAAFAPRKIRG
                     FIRNRPLLLAALMGLLLALLGTFYQGKTYGTGYHEAAQALHGIYEAPFGLAAAKWLAT
                     VFSYWAGVPGGIFTPSLTIGAVLGEHIAAIADISQGANIIVLICMAAFLAGATQSPIT
                     SAVVVMEMTGGQSLLFWMLIACIFASQVSRQFSPRPFYHASGMRFRQRVLQETTAQTG
                     NAPARPQTANSKTGMPSEN"
     gene            19340..20731
                     /gene="hrpA"
                     /locus_tag="ACFOAE_000435"
     CDS             19340..20731
                     /gene="hrpA"
                     /locus_tag="ACFOAE_000435"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003724 - RNA helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HFC6883994.1"
                     /translation="MFPDFSQTLSKDRHFLQSAFKNPNKYGGLSKVEEKYRKSHEIFL
                     KRLAALPKPEFDNTLPVHEKLDEIKKAIAEHQVTIICGETGSGKTTQLPKICLELGRG
                     AAGLIGHTQPRRLAARSVAERIAEELKSEIGSAVGYKVRFTDHTSRDACVKLMTDGIL
                     LAETQTDRYLAAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAER
                     FSQHFNGAPVLEVSGRTYPVEILYRPLTGKDEDDAEVELTDAIVDAADELARHGEGDI
                     LVFLPGEREIREAAEALRKSTLRRNDEILPLFARLSHAEQHKIFHPSGAKRRIVLATN
                     VAETSLTVPGIKYVIDTGLARVKRYSARAKVEQLHIEKISQAAARQRSGRCGRVSAGV
                     CIRLFSEEDFNNRPEFTDPEIARSNLAAVILRMASLKLGDVAAFPFLEMPDSRYINDG
                     FQVLLELGAVEAA"
     gene            20832..21959
                     /locus_tag="ACFOAE_000436"
     CDS             20832..21959
                     /locus_tag="ACFOAE_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN domain-containing protein"
                     /protein_id="HFC6883995.1"
                     /translation="MKHLLIDFENVQPQNLDKLLTENTHIWLFIGVLHKMLPISLVQS
                     LLRFGERVHLVQLQKTGKNALDFYLSYYLGQITATDPNAQIGILSRDGGYDVLVEHIL
                     KNHQAKGIVRLANIDEVQHQKIATEPPSALRENTPQPETTLKPQQPLTSYFQAALTAL
                     RRPDAFRPCRLHNLRQNLRKHILSDLFKEKTDEECEITTANVINKLKAQNFISIDEQE
                     TVSYHLSDNDLLQRIQRHILSQRPKTYADFQAVVQNRADALHLTVGTNDIQSFARHLR
                     DQNLIRQNNGKIEYAPFTEPKPQPTPKQPKKTAWEPDEIIWKKVIAALSLKNRPNKTK
                     TLRNTIQALTKSNAQETDKLLQHLQDTQVLRIDGTKIVYIK"
     gene            22136..23713
                     /gene="lpt3"
                     /locus_tag="ACFOAE_000437"
     CDS             22136..23713
                     /gene="lpt3"
                     /locus_tag="ACFOAE_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipooligosaccharide phosphoethanolamine
                     transferase"
                     /protein_id="HFC6883996.1"
                     /translation="MMKKSLFVLFLYSSLLTASEIAYRFVFGIETLPAAKMAETFALT
                     FVIAALYLFARYKTSRLLIALFFAFSIIANNVHYAVYQSWMTGINYWLMLKEVTEVGS
                     AGASMLDKLWLPALWGVAEVVLFCSLAKFRHKTHFSADILFAFLMLMIFVRSFDTKQE
                     HGISPKPTYSRIKANYFSFGYFVGRVLPYQLFDLSKIPVFKQPAPSRIGQGSIQNIVL
                     IMGESESAAHLKLFGYGRETSPFLTRLSQADFKPIVKQSYSAGFMTAVSLPSFFNVIP
                     HANGLEQISGGDTNMFRLAKEQGYETYFYSAQAENQMAILNLIGKKWIDHLIQPTQLG
                     YGNGDNMPDEKLLPLFDKINLQQGRHFIVLHQRGSHAPYGALLQPQDKVFGEADIVDK
                     YDNTIHKTDQMIQTVFEQLQKQPDGNWLFAYTSDHGQYVRQDIYNQGTVQPDSYLVPL
                     VLYSPDKAVQQAANQAFAPCEIAFHQQLSTFLIHTLGYDMPVSGCREGSVTGNLITGD
                     AGSLNIRDGKAEYVYPQ"
     gene            23815..26730
                     /locus_tag="ACFOAE_000438"
     CDS             23815..26730
                     /locus_tag="ACFOAE_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3418 domain-containing protein"
                     /protein_id="HFC6883997.1"
                     /translation="MDARSNPANVSDDLQNSSGHIGVNTRYRLTKLGEQMARLPIDPK
                     IARILLAAKKHDCMAEILVIASALSIQDPRERPLEARDAAAKAHERFTDKQSDFLAYL
                     NIWDSFQRERDKGLSNKQLVQWCRQYFLSHLRMREWRELHHQLAQTAIEMGLTTKEAA
                     FRRPPEGRQLTSSENAGDQDLSAKLKQKQLDKKQHRAQIRAAKEAGYEQIHRALLTGL
                     IANVGMKSPDGNDYTGARGSRFHLFPASALFKAKPKWVMAAELVETTRLYARDVAVIQ
                     PEWIEQEAPHLVRYHYFEPHWEQKRGEVVASERVTLYGLTVLPRRPVSYGKVAPEEAR
                     EIFIRSALVAQECDLKADFFVHNKKLIKEITELEHKSRKQDVLVDDEALFAFYNERLP
                     DFYTADAVSDDLHPTNPQQTAPSYAREERREGKTVAAQTNFSATTANPLPNPLPQEGE
                     QSAAASAVSNDPQPQKQPAPQKDRLKPLPLADIRTFQAWLKTAERENPRLLFLSRDDL
                     MQHAAAHITEEQFPKFWQTADGKFELSYRFEPHHPLDGVTLTLPLTVLNRISPAALEW
                     LVPGMLREKIQLLIKALPKQIRRICVPVPEFITQFLSQNPDRNAPILPQLAQAIAKTA
                     GDIRIFEQINQDEWAAFRLPEHCYFNLRIIDDGGQELAGGRKLHELQQQLGQAAAVTF
                     RDNTQEFERDNVTTWDIGTLPESIKFARGKQQLTGYLGLQKEKDGRIALRLCDTTEAA
                     EQAHRQGVIELMKLQLKEQVKDLNKGIQGFTQAAMLLKHINADTLCDDLTQAVCDRAF
                     IGEDELPRNEKAFKEQIKRARSRLPAVKEALSRYLQETAAAYAELNGKLGKHPLTHLL
                     KLRLQTLLAAGFATRTPWAQWPRLPIYLKAMTLRLEKYSSNPARDAAREADIQELEQM
                     WQEKTDSLIKQGLPISDGLAAFKWMIEELRVSLFAQELKTPYPVSVKRLLKMWEDLN"
     gene            complement(26753..27175)
                     /locus_tag="ACFOAE_000439"
     CDS             complement(26753..27175)
                     /locus_tag="ACFOAE_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="HFC6883998.1"
                     /translation="MTDIFTTSKRSFVMSKIHSKETKPEILVRKFLFSQGFRYRKNDK
                     RYAGKPDIVLPKYKTVVFIHGCFWYGHSCNKGHIPKSNTDFWLEKITKNCERDIKNET
                     ELEKIGFKVIVVWECELKNKAIGRERLNRLVREIKDAV"
     gene            complement(27179..28825)
                     /locus_tag="ACFOAE_000440"
     CDS             complement(27179..28825)
                     /locus_tag="ACFOAE_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02391 family protein"
                     /protein_id="HFC6883999.1"
                     /translation="MSEEKLKMSFEPTVIEHLGVKMYSHTVPAIAELIANAYDACATE
                     VEVRLFDKPEHKIVIKDNGIGMSFDEINDFYLRIGRNRREEKQASPCGRIPTGKKGLG
                     KLALFGLGNKIEISTIQGNERVTFTLDYAEIKKSERIYQPEFQKESVEPNTENGTTIT
                     LTELTKKQGYPLDNYVEHLSRLFDFPAQDFKIKVSLNGSEPKIIDGNLKYDLVTPQFE
                     WEYQDLATNISSLSSKFEQYEYSGLIQGKFITTEKPLKNNMKGITLFANGRMVNMPEF
                     FTDSESSHFYSYLTGWLSIDFIDNDDEDLIATDRTSLDWKHPKTSKLRVFLGEIVRAI
                     GQDWRKRRKKEKDDEVKGESGVDIENWKNKLPEKEREPVEVILNRLEDSELTNKEQAE
                     VISALHSIIPEYPYYHWRHLHQDLHTACNDFYNEKKDYLSAAIEAVKVFENKVQKQTG
                     LHSIDGRELIEQAFGSKNSILLLTNNKTKAEQNLEDGLEQLACGTWTGFRNPVQHELR
                     ANLSPSIFNDKDALDLISLVSYLLRKVEQTKKRSKVVSSK"
     gene            complement(28839..29894)
                     /locus_tag="ACFOAE_000441"
     CDS             complement(28839..29894)
                     /locus_tag="ACFOAE_000441"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC6884000.1"
                     /translation="MKNSKLKAVDFFCGGGGMSYGMQSAGIQVLAGIDYEPSCKETYE
                     ANINAKFIQADVFELQPETLEKELGLKKNDDDLILIGCSPCQYWSVIQTDKRKSEKSK
                     SLLLEFQRFVEYFNPGYVVVENVPGILSRMKESGLDNFIKLLEEKGFTVHFGIHNTAD
                     YGIPQSRKRFTLIANRITEEKLEPAKYSGKRLTVRDVLGMENGFPKIIAGHQDETDFM
                     HSCAGLSDINLKRLALIPKNGGNRLAFAHIPELQLECFIGKDNSFKDTFGRLWWDKPA
                     PTITTKFFSISNGRFAHPEEDRALSLREGATLQSFPRNYVFKAGSRDKIARLIGNAVP
                     PMYAEKIGRAIVDNIEC"
BASE COUNT         7400 a         8914 c         7300 g         6781 t
ORIGIN      
        1 tatcatttat cctttctaaa gccgttccgg tttgtccgac cggcggcttt gccccaatat
       61 ccccattttg gagacaccta tgttacgttt gactgcttta gccgtatgca ccgccctcgc
      121 tttgggcgcg tgttcgccgc aaaattccga ctctgcccca caagccaaag aacaggcggt
      181 ttccgccgca caatccgaaa gcgcgtccgt taccgtcaaa accgcgcgcg gcgatgttca
      241 aataccgcaa aaccccgaac gcatcgccgt ttacgatttg ggtatgctcg atactttaaa
      301 caaattgggc gtgaaaaccg gtttgtccgt cgataaaaac cgcctgccgt atttagagga
      361 atatttcaaa acgaccaaac ccgccggaac tttgttcgag ccggattacg aaacgctcaa
      421 cgcttacaaa ccgcagctca tcatcatcgg cagccgcgcc gccaaggcgt ttgacaaatt
      481 gaacgaaatc gcgccgacca tcgaaatgac cgccgatacc gccaacctca aagaaagtgc
      541 caaagagcgt atcgacgcgc tggcgcaaat cttcggcaaa caggcggaag ccgacaagct
      601 gaaggcggaa atcgacgcgt cttttgaagc cgcgaaaact gccgcgcaag gcaaaggcaa
      661 aggtttggtg attttggtca acggcggcaa gatgtcggct ttcggcccgt cttcacgact
      721 gggcggctgg ctgcacaaag acatcggcgt tcccgctgtt gacgaagcca tcaaagaagg
      781 cagccacggc cagcccgtca gctttgaata cctgaaagag aaaaatcccg actggctgtt
      841 cgtcctcgac cgaagcgcgg ccatcggtga agagggtcag gcggcgaaag acgtgttgga
      901 taatccgctg gttgccgaaa caaccgcttg gaaaaaagga caagtcgttt accttgttcc
      961 tgaaacttat ttggcggccg gtggcgcgca agagctgctg aatgcaagca aacaggttgc
     1021 cgacgctttt aacgccgcga aataatgaaa cggcggcatt cgatgccgtc tgaaacacgg
     1081 atgcaaaccg cttcctgtgt ttcagacggc attgcccgat acggaggctt caaacaaggc
     1141 tttccgctcc gacggttcgg actgccttgt ttgaatcttc tacgccgtaa cgcttttccc
     1201 ttctgtttat gactgccaaa cctttttccc tcaacctgac taacctcctg ctgctggcgg
     1261 tgttgtttgc cgtcagcctg tcggtcggcg ttgccgattt ccgctggtcg gatgtgtttt
     1321 cactgtccga cagccagcag gttatgttca tcagccgcct gccgcgcacg tttgcgattg
     1381 tgctgacggg cgcgtcgatg gcggtggcgg ggatgattat gcagattctg atgcgcaacc
     1441 gttttgtcga accttctatg gcgggcgcga gccaaagtgc ggctttgggt ttgcttctga
     1501 tgtccctgct gctgcctgcc gcgccgctgc cggtcaaaat gtcggttgcc gccgttgccg
     1561 cgctaatcgg aatgctggtg tttatgatgc ttatccgccg cctgccgccg acggcgcaac
     1621 tgatggtgcc gctggtgggg attattttcg gcggtgtgat tgaggcagtg gcgacgtttg
     1681 tcgcgtatga gtttgagatg ctgcaaatgt tgggcgtgtg gcagcagggc gatttttcga
     1741 gcgtgctgct ggggcggtac gagctgcttt ggattacggg cggtttggcg gtgtttgcct
     1801 atctgattgc cgaccggctg acgattttgg ggctgggcga gacggtgagc gtgaatttgg
     1861 gtttgaaccg gacggcggtg ttgtggtcgg ggctgattat tgtggctttg attacgtcgc
     1921 tggtcattgt aacggtcggc aatattccgt ttgtcgggct ggtcgtgccg aacatcatca
     1981 gccgcctgat aggcgacaaa ctgcgccaaa gcctgcctgc ggtcgccctc ttgggcgcgt
     2041 ctttggtttt attgtgcgac attatcggac gcgtgattgt gtttccgttt gaaattccgg
     2101 tatcgaccgt cttcggcgta ttgggtacgg cgttgttttt atggcttttg ttaaggaaac
     2161 ctgctcatgc cgtctgaaaa aaatatcggt tttatggcag gaagcagccg tccgttgtgg
     2221 gtcgcctttg cgctgttgct ggtttcctgc atcctgttta tgacgctcaa cgtcaaaggc
     2281 gattgggatt ttgtactgca cctgcggctg accaaacttg ccgcgctgct gatggtcgcc
     2341 tatgcggtcg gcgtgtccac gcaactcttc caaacgctga ccaacaatcc gattctgacc
     2401 ccttcgattt tgggtttcga ttcgctgtat gtgtttttgc agaccttgct ggtgtttacg
     2461 ttcggcggcg tgggctatgc ttccctgccg ttgacgggca aattcggctt tgaactggtc
     2521 gtcatgatgg gcggctcgct gctgctgttc tacacgctca tcaaacaggg cggacgcgat
     2581 ttgtcgcgca tgattttaat cggcgtgatt tttgggattt tattccgcag cctttcgtcg
     2641 ctgctttcgc gcatgatcga tcccgaagaa tttaccgccg cgcaggcgaa tatgtttgcc
     2701 ggattcaata ccgtccacag cgagcttttg ggcataggcg cgctgattct gctcgtcagc
     2761 gcggcggtcg tttggcgcga acgctaccgc ttggacgtac accttttggg gcgcgaccaa
     2821 gccgtcaatt tgggcatcag ctacacgcgc aacaccttat ggatactgct ttggattgcc
     2881 gcattggtgg cgacggcgac cgccgtggtc ggtccggtaa gctttttcgg gcttctcgcc
     2941 gcctcgcttg ccaaccactt ttccccatcc gtgcgccatt ccgtccgcct gccgatgacg
     3001 gtttgtgtcg gcggcatcct cttggtcggc ggacagaccg tattcgaaca cttcttgggc
     3061 atgaaggcgg tattaagcgt ggtggtcgaa tttgcgggcg gactcgtttt cctctatctc
     3121 gttttaaaac acaaaaaatg acggatgccg tctgaacggc agcccgactc gaaaggacaa
     3181 accatatgac gcaagaacgt ttcccatcat tcttcaacca agccccgacc atcaccgtca
     3241 gagacccgct tgccgcattc ctcggcgcgg ccgaaaacgg catcctcact taccgctacg
     3301 ccgatgccgt gcgcctgtgc ggacattcct gcccgaccgt cgcgggcgcg tacctgatgg
     3361 ttatcaaagg tctgaaagcc ctttacggcg aagagctgcc cgaacgcggc agcatcgaag
     3421 ccgccatgca gggagcgcgt gacgaaggca cggtcggcgt aaccgcgtcc gtcgtccaac
     3481 tccttaccgg cgcagccccc gaaaccggct tcggaggcat cggaatacag ggacgcttcg
     3541 cccgccgcaa cctcttatcc tttggtgcag gcgaaatcaa cggcacactg accctgcgcc
     3601 gcaaagacaa cggcaaaacc gtcgccgtca gcctcaacgc cgccccgaaa cccttcgcac
     3661 ccgaaatgcg cgaacttatg cccaaagccg tcggtggcag cgcaagcgca gaagaactcg
     3721 aacgcttcgg acaactctgg caggcacgcg ttaaagcatt tttgaccgaa tcggcggacg
     3781 acccgcagtt cgtcatcgtc cgcgaagtgt gaacgttcag acggcattcc gaatttcaaa
     3841 tgccgtctga acccccgcta aacaacaaca aacctacgcc cgacaagcat ccgccatgat
     3901 taccatccgc aacgtcagct accgcatcgg cacacgcccc atcctcgaca acgtcagcct
     3961 cgacatcccc gaaggcggca ttaccgccct cgtcggcccc aacggcgcgg gcaaatccac
     4021 cctgttttcc tttatggcgc ggctgcgccc gcttgaaagc ggcagcatcg cctaccgcgg
     4081 caaaaacctt gccgacaccc ccaccgccga actcgccaaa actctgtcca tcctcaccca
     4141 agaaaacagc atcatgagcc gcattaccgt gcgcgacctg ctgatgttcg gacgttaccc
     4201 ctaccatcaa ggcagaccga ctgccgaatg ccgccgtatc gttaacggtg caatcgaaga
     4261 attccacctg caagacctct ccgaccgcta tctgaccgag ctctccggcg gccaacgcca
     4321 acgcgccatg attgcgatgg tgttctgcca aagcaccgac tacgtccttt tggacgaacc
     4381 gctgaacaac ctcgatatgt atcacgcccg ctcgctcatg cagattctgc aaaagctcac
     4441 gcgcgaacac aaacgcacca ccgtcgccgt attgcacgac atcaaccagg ccgccgccta
     4501 cgccgaccac gtcgtcgcca tgaaaaacgg caaagccgtc ctgaccggca cgcccgaaga
     4561 agtgttcacc gtacacaaca tcaaagaact gttcgacatg gacgtggacg tactcgacta
     4621 cgaaggcaaa aaactcatcg tccaccatat ctgaacccga aaaaaatgcc gtctgaacat
     4681 tcagacggca ccccatatcc tgacaaaatt aaggcacgac acaggcagaa ttgacatcag
     4741 cataatatgc acatattaac agatattaat gccgaactac ctaactgcaa gaattaaata
     4801 aataaataaa taaataaata aataaataaa ttgcgacaat gtattgtata tatgcctcct
     4861 ttcatatata ctttaatatg taaacaaact tggtggggat aaaatactta caaaagattt
     4921 ccgccccatt ttttatccac tcacaaaggt aatgagcatg aaacactttc catccaaagt
     4981 actgaccgca gccatccttg ccgccctcag cggcagcgca atggcagaca acgcccccac
     5041 cgctgacgaa attgccaaag ccgccctagt taactcctac aacaataccc aagacatcaa
     5101 cggattcaca gtcggagaca ccatctacga cattaaaaat gacaagatta ccaaaaaaga
     5161 agcaacagaa gccgatgttg aagctgacga ctttaaaggt ctgggtctga aagaagtcgt
     5221 ggctcaacac gaccaaagcc ttgccgacct gaccgaaacc gtcaatgaaa acagcgaagc
     5281 attggtaaaa accgccgcgg ttgtcaatga catcagtgcc gatgtcaaag ccaacacagc
     5341 agctatcggg gaaaacaaag ctgctatcgc tacaaaagca gacaaaaccg aactggataa
     5401 agtgtccggc aaagtaaccg agaacgagac tgctatcggt aaaaaagcaa acagtgccga
     5461 cgtgtacact aaagctgagg tgtacaccaa acaagagtct gacaacagat ttgtcaaaat
     5521 tagtgacgga atcggtaatc tgaacactac tgccaatgga ttggagacac gcttggccgc
     5581 tgccgaacaa tccgttgcag accacggtac gcgcttggct tctgccgaaa aatccattac
     5641 cgaacacggt acgcgcctga acggtttgga tagaacagtg tcagacctgc gtaaagaaac
     5701 ccgccaaggc cttgcagaac aagccgcgct ctccggtctg ttccaacctt acaacgtggg
     5761 tcggttcaat gtaacggctg cagtcggcgg ctacaaatcc gaatcggcag tcgccatcgg
     5821 taccggcttc cgctttaccg aaaactttgc cgccaaagca ggcgtggcag tcggcacttc
     5881 gtccggttct tccgcagcct accatgtcgg cgtcaattac gagtggtaag cagcatctcc
     5941 cgataaagaa accgcagccc tgcaaggctg cggtttttat tttctatccg gccgtcaaac
     6001 cgccgcgtcc gaacgttcgc ccgtgcggat acggattgcc tcctcgaccg gcagcacaaa
     6061 aatcttgccg tcgccgattt tgcccgaacg cgccacctcg acaatcacgt caatcgcgcg
     6121 ttccacagcg tcatccgcca acaccagctc gattttgacc ttgggcagga aatcgacagc
     6181 gtattccgcg ccccggtaaa tctccgtatg ccccttctgc ctgccgaacc ctttgacctc
     6241 gctgacggtc atacccgtaa tgccgatttc cgtcaacgcc tcgcgcacgt cgtcgagttt
     6301 gaacggtttg acaatcgcct cgattttttt cataaaattt cctttgaaca aacaatacaa
     6361 acacatccga aaaacgggaa cctcccgtca gattgtcaac attttaagcc aaaataccca
     6421 agcaatacag ccccgttgcg cgtataatga cagattttcc aaccgcattt gagagccgaa
     6481 tccatgtctg tcgttttgcc cttgcgcggc gttaccgccc tttccgattt ccgtgtcgaa
     6541 aaactcttgc aaaaagccgc cgcactcgga ctgcccgaag tcaaattaag cagcgaattt
     6601 tggtatttcg ccggcagcga gaaagcattg gatgccgcga ctgtcgaaaa actgcaagcc
     6661 ttgttggcgg cgcaaagcgt tgaacaaacg ccaaaagcgc gcgagggctt gcatttgttt
     6721 ttggtaacgc cccgtttggg tacgatttcg ccgtgggctt ccaaggcgac caatatcgcg
     6781 gaaaactgcg gtttggcagg catcgagcgc atcgagcgcg gcatggcggt gtggctggaa
     6841 ggtgcgctta ccgatgaaca gaaacggcaa tgggcggcgt tgctgcacga ccgcatgacc
     6901 gaatcggtgc tgcccgattt tcagacggca tccaaattat tccaccatct cgaatccgaa
     6961 accttttcca ccgttgatgt tttaggcggc ggtaaagagg ctttggtcaa agccaatacc
     7021 gaaatgggtt tggcactctc cgccgacgaa atcgattatc tggttgaaaa ctatcaggct
     7081 ttgcagcgca atccgtccga tgttgaattg atgatgttcg cgcaggcaaa cagcgaacac
     7141 tgccgccaca aaatcttcaa cgccgatttc atcctcaacg gcgaaaaaca accgaaatcc
     7201 ctcttcggta tgatacgcga cacgcacaac gcgcatcccg aaggcacggt cgtcgcttat
     7261 aaagacaact cgtccgtaat cgaaggcgcg aaaatcgagc gtttctatcc gaatgcggcg
     7321 gaaaaccaag gttaccgttt ccacgaagaa gacacgcata tcatcatgaa agtggaaacg
     7381 cacaaccacc cgaccgccat cgcgccgttt gcaggcgcgg caacaggcgc gggcggcgaa
     7441 atccgcgacg aaggcgcaac gggcaaaggt tcgcgtccga aagcaggctt gaccggcttt
     7501 accgtctcca acctcaacat ccccgacctc aaacagccgt gggaacaaga ttacggcaag
     7561 ccggaacata tttcctcgcc gctggacatc atgattgaag gccccatcgg cggcgcggcg
     7621 ttcaacaacg aattcggccg ccccaacctc ttgggctact tccgcacttt tgaagaaaaa
     7681 tttgacggtc aggttcgcgg ctaccacaaa ccgattatga ttgccggcgg cttgggcagc
     7741 attcaggcgc agcagacgca taaagacgaa atccccgaag gcgcgttgct gatccaactg
     7801 ggcggcccgg gcatgcttat cggcttgggc ggcggcgcgg cttcttcgat ggataccggc
     7861 acgaacgacg cttctttaga cttcaactcc gtacaacgcg gcaaccccga aatcgaacgc
     7921 cgcgcgcagg aagtcatcga ccgctgctgg cagctcggcg acaaaaaccc gattatctcc
     7981 atccacgacg tgggcgcagg aggtttgtcc aacgccttcc ccgaactggt caacgatgcc
     8041 ggacgcggcg cggtattcga gctgcgcgaa gtgccgttgg aagaacacgg tttaacgcct
     8101 ttgcaaatct ggtgcaacga atcgcaagag cgttatgtct tgtcgatttt ggaaaaagat
     8161 ttggatacct tccgcgccat ctgcgaacgc gaacgctgcc cgtttgccgt ggtcggcacg
     8221 gcgactgacg acggtcattt gaaagtacgc gacgatttgt tcgccaacaa tcccgtcgat
     8281 ttgccgttga acgtcttgct cggcaaactg cccaaaacca cgcgtaccga caaaacagtt
     8341 acgccatcta aaaaaccgtt tcacgccgac gatatcgaca tcaccgaagc cgcctaccgc
     8401 gttttgcacc tgcctgccgt agccgccaaa aacttcctga ttaccatcgg cgaccgcagc
     8461 gtcggcggca tgacccaccg cgaccaaatg gtcggcaaat accaaacccc cgtagccgac
     8521 tgcgccgtta ccatgatggg cttcaatacc tatcgcggcg aagcgatgtc tatgggcgaa
     8581 aaaccgaccg ttgccctgtt tgacgcgcct gcttcaggca gaatgtgcgt cggcgaagcc
     8641 atcaccaaca tcgcggcggt caacatcggc gacatcggca acatcaagct ctccgccaac
     8701 tggatggcgg cgtgcggcaa cgagggcgaa gacgaaaaac tctaccgcac cgtcgaagcg
     8761 gtttccaaag cctgtcaggc attggatttg agcattcccg tgggcaaaga cagcctgtcg
     8821 atgaaaactg tgtggcagga cggcgaagag aaaaaatccg tcgtctcgcc attgagcctg
     8881 attatctctg cgttcgcgcc ggtcaaagac gtgcgcaaaa ccgttacgcc cgaattgaaa
     8941 aacgtcgaag acagcgtatt gttatttatc gatttgggct tcggcaaagc gcgtatgggc
     9001 ggctcggcgt ttggtcaggt gtacaacaat atgagcggcg acgcgcccga tttggacgat
     9061 acaagtcgtc tgaaagcgtt ttacaacgtg attcaacagc ttgtcgccga agacaaactc
     9121 ttggcatacc acgaccgcag cgacggcggt ttgtttgccg ttttggtaga aatggcgttt
     9181 gcggggcggt gcggcttgga tatagattta aatttattgc ttgcacaaac atttattacc
     9241 aaccataccg ctctgtctca atcattgcgg actgaagagg taaaagcgtt ggctgaatgg
     9301 caagaaacca ttgcccgcac attatttaat gaagagttgg gtgctgttat ccaagttaga
     9361 aaacaagatg ttgccgatat tatcaattta ttctatcaac aacagctgca tcataatgtc
     9421 tttgaaatcg gtacgttaac tgatgagaac acgttaatca tccgcgacgg gcaaacgcac
     9481 cttatttctg acaacctaat caaactgcaa caaacctggc aagaaaccag ccatcaaatc
     9541 caacgcctgc gcgacaaccc cgcctgcgcc gacagcgagt tcgccctgat tggcgacaac
     9601 gaccgcagcg cattgtttgc cgacgtgaag tttgacgtga acgaagacat cgccgcacct
     9661 ttcgtcaaca gcggcgcgaa acccaaaatc gccatcctgc gcgaacaggg cgtaaacggg
     9721 caaatcgaaa tggccgccgc gttcactcgc gccggtttcg atgcctacga cgtgcatatg
     9781 tccgacctga tggcaggccg cttccgcctt gccgacttca aaatgctggc ggcgtgcggc
     9841 ggtttcagct acggcgacgt actcggcgcg ggcgaaggct gggcgaaatc gattctgttc
     9901 caccctgctc tgcgcgacca gtttgccgcc ttcttcgccg acccggacac gctgacattg
     9961 ggcgtgtgca atggctgcca aatggtcagc aaccttgccg agattatccc gggcgcagaa
    10021 gcatggccta aattcaaacg caacttgagc gaacagtttg aagcgcgcct aagcatggtt
    10081 cacgtcccaa aatcagcctc cctgattctg aacgaaatgc aaggctccag cctgcccgtc
    10141 gtcgtcagcc acggcgaagg ccgcgccgac ttcgcgcttc acggcggcaa catttctgcc
    10201 gatttgggca ttgcgttgca atatgtggac ggacaaaacc aaattaccca aacctacccg
    10261 ctcaacccca acggctcgcc gcaaggcatc gccggcgtga ccaacgccga cggccgcgtt
    10321 accatcatga tgccgcatcc tgaacgtgta taccgcgccg cacaaatgag ctggaaaccg
    10381 gaagactgga cggaattgtc cggctggtac cgcctcttcg ccggcgcacg taaagccttg
    10441 ggctaaccgc cctactcaaa ccaatgccgc ctgaagaata tttcagacgg cgttccggca
    10501 taccatcctt taaacggtat ccgtccaccg aggaacactc atgaaaatca cacccgtcaa
    10561 agccttgacc gacaactaca tctggatgat acagcacggc aaccatgccg tctgcgtcga
    10621 cccttccgaa ccctcgcccg tcttggaatt cctcgtccgc aaccgcctca tgcttgccca
    10681 aacatgggta acgcaccccc atcccgacca cgagggcggt gcggcggcac tctggcgcgg
    10741 ctacatggaa tcgcccgttt acggcgaatc cgacatcgaa gcagcaaccc acaccgtaac
    10801 cgccggcacc caattcacct tcggcgacgg acaggttacc gtttgggcaa cacccggcca
    10861 cacagaccgc cacaccagct accttctcga aacttcagac ggcatacacg tcttttgcgg
    10921 cgacaccctt ttttccgccg gctgcggacg cgtgtttacc ggcacaatcg aacagcttta
    10981 cgacagcttc caacgcttca accgcctgcc tgaaaacacc ctgttctacc cggcacacga
    11041 atacaccgcc gccaacctgg attttgccgc ccatatcgag ccggacaacg ccgacattca
    11101 ggcggcattg aaggcggcag aacgcacgcc caccctgccc gttaccctcg cccacgaacg
    11161 ccgcgtcaac ccgttcttac ggacagaaat ccccgccgtc cgccaacgtg ccgaagccct
    11221 agtcggcaaa acgctgaaca gcggtttgga agtattcgcc gccctgcgcg aactgaaaaa
    11281 cgcctaccgc tgacctgccc tccgaaaaat gccgtctgaa acccacgttt cagacggcat
    11341 ttgcgttaaa aatagtaaac cgtttcaaaa gggagtagaa tagtgccgtt tccaaccctg
    11401 cgcctgtacc gtcaggcttt tattatggac cttcccagtt cgtttttact gaacacccct
    11461 tccgattcca aacgacaata accatcccgc cggaatgcct ccccgcacac ggcgggcgga
    11521 gcatttatga gcatcgaacc aacccctccg aaccttgaaa acgacggtat cgaaaacgat
    11581 gtagaacgcg tttccgccga tttcgaccgt gtccactccc tctgcgaaat cctcgaacct
    11641 gcttttgaac aaatcgaaaa cggtacaccg ctcgaagacg cgccgctgcg cgacaagctg
    11701 accgagctga ccgtcctctt gagcgagctg caccctgccg acgtggcggc ggtattggaa
    11761 tcgctaccgc cgcgcgaacg caatatcgtc tggattctgg tcaaaccgga agacgacggc
    11821 gaagtattgc tggaagtatc cgacgcggtg cgcgaaacgc tgatcgagtc gatggacaaa
    11881 gacgaattgt tggcagcggt cgatgatttg gacgcggacg aattggcgga actggcagac
    11941 gatttgccgc accaagtggt ttacgaagcg ctacaaaccc gcgatgagga agaacgcgcc
    12001 caagtcaaag cggcaatgtc ctacgaagac aaccaagtcg gtgcgattat ggacttcgag
    12061 ttggtcagca tccgcgccga tgtcgcctgt gaagtggtgc tgcgctatct gcgccgcttc
    12121 gacagcctgc ccgaccatac cgacaagatt tttgtggtcg atgaaaacga cgtactgcaa
    12181 ggcgtgctgc ccatccgcaa acttttggtc gccgatcccg aagatttggt ggaaaacgtg
    12241 atggcgaaag atgtcgtgcg tttccgcgcc gaagacgacg tggaagaagc ggcgcaggcg
    12301 tttgaacgct acgacttggt aactgcgccg gttgtcgatg aaaacaaaaa gctcatcggt
    12361 aggattaccg ttgacgagat ggtggacgtg atccgcgaag aatccgaagc ggatatgttg
    12421 aacatggcgg gtttgcagga agaggaagac ttattcgccc ccgtcttgga ttccgtcaaa
    12481 aaccgctgga tgtggctcgc cgtcaacctc tgcaccgcct tcctcgccag ccgcgtcatc
    12541 ggcgcgtttg aaagcagcat cgaaaaaatc gtcgcactcg ccgcgctgat gcccatcgtc
    12601 gccggcatag gcggtaactc gggcaaccag acgattacca tgattgtccg cgcgatggcg
    12661 atggggcagc tgacggatat gcaggcggga cgtttgctga aaaaagaagt cagtgtcgcc
    12721 ctggtcaacg gcatcatttg gggagcggtc atgggcgcag tatcttggct gctctacggc
    12781 agcctcggca tcgggctggt tatgattgcc gcgatgacgc tcaacctcct gctggcggca
    12841 accgtcggcg tattgattcc cgtggtaatg gaaaagttcg gacgcgaccc cgcgctgggc
    12901 agctcggtgc tgattacggc ggtaacggat tccggcggct tcctgatttt cttgggtctc
    12961 gccaccctgt tcctgcttta aatgccgtcc ggacccgcgc aaaaatgccg tctgaagcgg
    13021 aagctgcttc agacggcatt tgactattta tccttgttgc acaagattat tggacggtat
    13081 gccggggcag ccctttggca acgccgacca catcctcccc gaacagcacg ttgacatcgg
    13141 tttcgtcaaa cacatatttg ctgtggcaga aatcgcaatc gacttcgatg ctgccttgtt
    13201 ccaccaccac gccgccgact tcttccccgc ccagcatcaa cagcatatcg ctgactttgc
    13261 cgcgcgaaca ggtgcatgaa aattcaaacg tttccggctc gaacacgcgc ggcggcgttt
    13321 cgtggaacag gcggtataaa acgtgttgcg catccaattc tgccagctcc tccgccgtca
    13381 gcgtgcgcgc cagcgtactg acgtgttccc atgcctcttc atccaacacc tcttcaggca
    13441 gacgctgcac cagcagaccg cccgccgctt catcgcttgc agacaggacg atgtgcgtat
    13501 caagctgttc ggaacgtttc atatagttca tcaacatttg cgcgataccg tcgccttcca
    13561 aaggcactac gccctgccag ggttcgccgt ctttgggctg cagcgtcagc acgaatacgc
    13621 cgccctcgcc caaaagatcg accaaacttt catcttcacc gatttctgcc gcctcgtccc
    13681 accgcgcggt tgcacggacg gtacggtcgg aagtcgcttc cgcaaccagc attttcagcc
    13741 gcccctgccc ctgaacctgc acaatcagcg tgccttcgtt tttgaggttg cccgacagca
    13801 gaacaccggc agccaacagc tcgcccaagg cgcggcggat ggcggcggga tagtttttct
    13861 gttttacaat gtgctgccac acgttttcca gacggacgtg cagcccgcgc acgggcatat
    13921 cgtcgaagat aaagcgggta cgcacatcgg cgcggttgat ggcggtttga ttcatgattt
    13981 tctctgactg attgttcgga tggcggctat atggttgcgg tcggcgcgaa aacaagacgg
    14041 acggcggatg cgcttcccaa attatcaata aattatataa aaatcaacat attaactcaa
    14101 tctaacaagc cgttttttgc caaacagccg tttttttata tacaatcaac aagatatttt
    14161 cgactgatac agcataacat cgcacggcgg cacgatgcct cctgcgcgga aacaccgata
    14221 tggattcttt tttcaaaccg gcagtttggg cggttttgtg gctgatgttt gccgtccgcc
    14281 ccgcccttgc cgacgagttg accaacctgc tcagcagccg cgagcagatt ctcagacagt
    14341 ttgccgaaga cgaacagccc gttttaccca tcaaccgagc ccccgcccga cgggcgggca
    14401 atgccgacga actcatcggc agcgcgatgg ggcttaacga acagcccgtt ttacccgtca
    14461 accgagtccc cgcccggcgg gcgggcaatg ccgacgaact catcggcaac gcgatggggc
    14521 ttaacgaaca gcccgtttta cccgtcaacc gagcccccgc tcggcgggcg ggcaatgccg
    14581 acgaactcat cggcaacgcg atgggacttt tgggtattgc ctaccgctac ggcggcacat
    14641 cggtttctac cggttttgac tgcagcggct tcatgcagca catctttaaa cgcgccatgg
    14701 gcatcaacct gccgcgcacg tcggcagaac aggcgcggat gggtacgccg gttgcccgaa
    14761 gcgaattgca gcccggggat atggtgtttt tccgcacgct cggcggcagc cgcatttccc
    14821 atgtcggact ttatatcggc aacaaccgct tcatccacgc gccgcgcacg gggaaaaata
    14881 tcgaaatcac cagcctgagc cacaaatatt ggagcggcaa atacgcgttc gcccgccggg
    14941 tcaagaaaaa cgacccgtcc cgctttctga actgatttcc caaggaatac gcaatgagta
    15001 tgcccgaaat gcccaaatgg tacgacgatg acggacagat cgtgtcctgt accgaaaagg
    15061 tcaaagtgat gtccgaaaat atggccgagc tgtatcagac ggcacaagac gcgtttgaag
    15121 acgcgctgct gatgggttgc ggcgaacgtc agttgcgcga ttacctgctc gcgctgattg
    15181 aaggtttgga aaatccctac cgcaaagtct gaacacgccc cggttgctgc ggcacggttt
    15241 atccgtgccg tttttgcgtt tgtgcgcggc ttcggctttt cagacggcat atttgacgtt
    15301 atgattaaac agttaacaag atttatcaca acgccgtcaa aagacagaca cacaacatga
    15361 acatcatccg cgcgctcctc atcatcctcg gctgcctcgc caccggcgaa accgccgttt
    15421 tcctagcagg catcaaactg cccggcagca tcgtcggcat gggcgtgctg tttgcgcttt
    15481 tgcaggcggg ttgggtcaaa acgtcttggc tgcaacagct taccgacgcg ctgatggcga
    15541 atctgacgct gtttctcgtg ccgccctgcg tggcggtcat cagctatttg gatttgattg
    15601 ccgacgattg gttttcgata ctggtttccg cctccgccag cactttgtgc gtactgctga
    15661 ttacaggcaa ggttcaccgc tggatacgga gcattatctg atgaacgaaa tcctcaggca
    15721 gcccagcgtt ctgcttttcc tcacgcttgc cgtgtacgcg cttgcgatta tcgtgcgcac
    15781 gcgcacgggc aatatcttct gcaaccccgt actcgtcagc accgtggtgc tgattgccta
    15841 cctgaaaatc ctcggtatcg attacgcggt gtaccacaac gccgcgcagt ttatcgattt
    15901 ctggctcaag cccgccgtcg tcgtgcttgc cgtgccgctc taccaaaacc gccgtaaaat
    15961 cttcaaccaa tggctgcccg tcatcgtttc acagcttgcg ggcagcgtta cgggcattgt
    16021 tacggggatg tattttgcca aatggctggg cgcggaacgc gaagtcgtcc tctcgctcgc
    16081 gtccaaatct gttaccaacc ccatcgccat tgaaattacc cgctccatcg gcggcattcc
    16141 cgccattacc gccgccaccg tcatcattgc cggtctagtc ggacagattg ccggttacaa
    16201 aatgctgaag aacacagtcg tcatgccctc gtccgtgggt atgtcgctcg gcacggcttc
    16261 gcacgcgatg gggattgccg cctcgctcga acgcagccgc cgcatggcgg catacgcggg
    16321 actggggctg acgttcaacg gcgtactgac cgcgctgatt gcgccgctgc tcatccccgt
    16381 tttgggattt tgaacccgtt tcagacggca tttcagccca tgctgtctga acgccgacac
    16441 actcgcaagg agaaccgtta tggctgtcaa cctgactgaa aaaaccgccg aacaactgcc
    16501 cgacatcgac ggcattgccc tctacaccgc ccaagcaggc gtgaagaagc ccgggcatac
    16561 cgacctgaca ctgattgccg tagccgccgg cagcaccgtc ggtgcagtct tcacgaccaa
    16621 ccgtttctgt gccgcgcccg tccacatcgc caaatcgcac cttttcgacg aagacggcgt
    16681 gcgcgccctc atcatcaaca cgggcaacgc caacgcgggt acgggcgcac agggcagaat
    16741 cgatgctttg gcagtgtgtg ccgccgccgc ccggcaaatc ggctgcaaac cgaaccaggt
    16801 gctgcccttc tccaccggcg tgattctcga accgctgccc gcagacaaaa tcatcgccgc
    16861 gctgcccaaa atgcagcctg ccttctggaa cgaagcggca cgcgccatca tgaccaccga
    16921 caccgtgccc aaagccgcct cgcgcgaagg caaggtcggc gacaaacaca ccgtccgcgc
    16981 cacgggcatc gccaaaggct cgggcatgat tcatcccaat atggcgacca tgctcagttt
    17041 catcgccacc gatgccaaag tttcccaacc cgtcctccaa ctgatgacgc aggaaatcgc
    17101 cgacgaaacc ttcaacacca tcaccgttga cggcgacacc agcaccaacg acagcttcgt
    17161 catcatcgcc tccggcaaaa acagccaaag cgaaatcgac aacatcgccg acccgcgtta
    17221 cgcccaactc aaagaattgt tgtgcagcct cgcgctcgaa ctcgcccaag ccatcgtccg
    17281 cgacggcgaa ggtgcgacca agttcatcac cgtccgcgtc gaaaacgcca aaacccgcga
    17341 cgaagcccgc caagccgcct acgccgtggc acgttcgccg ctggtcaaaa ccgccttttt
    17401 cgcctccgac cccaacctcg gcaggctgct cgccgccatc ggttatgccg gcgttgtcga
    17461 cctcgatact gacctcgtgg aaatgtatct cgacgatatt ttggttgccg aacacggcgg
    17521 acgcgccgca agctacaccg aagcacaagg gcaggcggtg atgtcgaagg ccgaaatcac
    17581 cgtccgcatc aagctgcatc gcggacaagc cgccgccacc gtctatacct gcgacctgtc
    17641 gcacggatac gtttccatca acgccgacta ccgttcctga cccgacacgg cttcagacgg
    17701 catacataaa atgccgtctg aaccgccgga caacatacca tgacctccac attcccccgc
    17761 cgcctcgccc gcaaaatccg ccaaacccgc cgcctgtcgc gcaaaagcat cgcctttctg
    17821 ttccttttgg caggttcggc actcgtcgcc ctgaccgcgc tgttttttgc ccatcttgcc
    17881 gattttgcgc tggaactgaa cgccaaactg gttcaacaat acccgtggtt cgcgtgggtc
    17941 gcgcttcctt tgggtttgcc gcttattgcg tggctcacac gcaaattcgc ccccttcacc
    18001 gccggcagcg gcatcccgca ggtcatcgcc tcactgtcgc tgccctacgg cgcacagaaa
    18061 acgcggctga tccgcctcgg gcagacgctg ctgaagattc cgctgacctt tttgggtatg
    18121 ctgttcggcg cgtccatcgg acgcgaaggt ccgtccgtgc aggtcggcgc ggcagtgatg
    18181 ggcgcgtggg gcgcgtggtg caagaaacac ggcttggcat tcaaagggat gcaggaaaac
    18241 gatttgatgg cggcgggcgc ggcgggcggt ttggcagccg cgttcaacgc gccgctggcg
    18301 ggcgtgattt tcgccattga ggaactcggg cgcggcatca tgttgcgctg ggagaggcaa
    18361 attcttttgg gcgtgctcgc ctccggtttc atacaggtcg ccattcaggg caacaacccg
    18421 tatttttccg gcttcaacgg cggcgtattg gaacatatct ttctgtgggt cgcactgtcc
    18481 ggcctggttt gcggcgcggc gggcgggctg ttcggacgtt tgctctatcg cggtgcggcg
    18541 gcgtttgcac cgcgcaagat acgcggcttc atccgcaacc gtccgctgct gctggcggca
    18601 ctgatggggc tgctgctcgc cctgctcggc acgttctacc aaggcaaaac ctacggcacc
    18661 ggctaccacg aagccgccca agccctgcac ggcatctacg aagccccctt cggactcgcc
    18721 gccgccaaat ggctcgccac cgtattcagc tattgggcag gcgttccggg cggcattttc
    18781 actccctcgc tgaccatagg cgcggttttg ggcgagcata tcgccgccat cgccgacata
    18841 tcgcagggtg caaacatcat cgtcctcatc tgcatggcgg catttctggc gggcgcgaca
    18901 caatccccga ttacttccgc cgtcgtcgtc atggaaatga cgggcggaca aagcctgctg
    18961 ttttggatgc taattgcctg cattttcgcc tcgcaggttt cgcgccagtt ttcgccgcgt
    19021 ccgttctacc acgcatcggg aatgcgcttc cgccagcgcg tgcttcagga aaccaccgcc
    19081 caaaccggca atgcgcccgc aagaccgcaa acagcaaaca gcaaaacggg aatgccgtct
    19141 gaaaattaaa acgcccccga tcaaacgccg gcagccgcct tgatttgaat accgttcctc
    19201 cgccgcttga aatttcagca acaatgccgt ctgaacgaca gaatgcggtt ttcagacggc
    19261 atttccccat cccgatattg cccgaaccca accaaagcgt ttgctataat tctatttttt
    19321 taccgcacac gcaccaatca tgtttcccga tttctcccaa accctctcca aagaccgcca
    19381 cttcctgcaa tccgccttca aaaatcccaa caaatacggc ggcttgtcca aagtcgaaga
    19441 aaaataccga aaatcgcacg aaatcttttt gaaacgtttg gccgccttgc ccaaacccga
    19501 attcgacaac accctgcccg ttcacgagaa acttgacgaa atcaaaaaag ccattgccga
    19561 gcatcaggta acgattattt gcggcgaaac cggttcgggc aaaaccacgc agctgcccaa
    19621 gatttgttta gaactcgggc gtggggcggc ggggctgatc gggcataccc agccgcgccg
    19681 tttggccgcg cgctccgtgg cagagcggat tgccgaagag ctgaaatccg aaatcggcag
    19741 cgcggtcggc tataaagtac gcttcaccga ccacacctcg cgcgatgcct gcgtcaagct
    19801 gatgaccgac ggcatcctgc tggcggaaac gcagaccgac cgttatctcg ccgcctacga
    19861 cacgattatc attgacgaag cgcacgagcg cagcctgaac atcgacttcc ttttgggcta
    19921 tttgaaacaa ctgctgccgc gccgccccga tttgaaagtc atcatcacct cggcaaccat
    19981 agacgcagaa cgcttctccc aacacttcaa cggcgcgccc gtgctggaag tgagcggacg
    20041 cacctatccc gtcgaaatcc tctaccgacc gctgaccggc aaagacgaag acgatgcaga
    20101 agtcgagctg accgacgcga ttgtcgatgc agccgacgaa ttggcgcgac acggcgaagg
    20161 cgatatcttg gtattcctgc cgggcgagcg cgaaatccgc gaagccgccg aagccctgcg
    20221 caaatccacg ctacgccgca acgacgaaat cctgcccctg ttcgcacgcc tgtcgcacgc
    20281 cgagcagcac aaaatcttcc acccctcagg cgcgaaacgc cgcatcgtgc tggcaaccaa
    20341 cgtcgccgaa acctcgctta ccgtgccggg catcaaatac gtcatcgaca ccggcctcgc
    20401 acgcgtcaaa cgctattccg cacgggcgaa agtggagcag cttcatatcg aaaaaatctc
    20461 ccaagccgcc gcccgccaac gctccggccg ctgcggacgc gtctccgcag gcgtatgtat
    20521 ccgattgttt tcagaagaag atttcaacaa ccgccccgaa tttaccgacc ccgaaatcgc
    20581 ccgcagcaac ctcgccgccg tcatcctgcg catggcatcg ctgaaactcg gcgacgtagc
    20641 ggcattccca tttttagaaa tgcccgattc gcggtatatt aatgatgggt ttcaggtgtt
    20701 gctggaatta ggggcagtgg aggccgcctg aaaacaagta ggatatacac ttctacctga
    20761 caaagaccaa caaacgataa aactacggca catctagatg cccaacctac aacattgcac
    20821 acggtaaaaa catgaaacac ttactcatcg attttgaaaa cgtccagccg caaaacttag
    20881 acaaattact aaccgaaaat acccatattt ggctatttat aggtgtatta cacaaaatgt
    20941 tacctattag tctggtgcaa tccctactac gtttcggcga acgtgtccat cttgtccagt
    21001 tacaaaaaac ggggaaaaac gcattggatt tttacctgtc ctattacctc ggacaaatta
    21061 ccgccacaga ccccaatgcc caaatcggca tactctcgcg tgatggagga tacgatgttc
    21121 tggtcgaaca tattttgaaa aaccaccagg cgaagggtat cgtgcgccta gccaatatag
    21181 atgaagtaca acatcagaaa attgctaccg aaccgccgtc agcattgcgg gaaaacactc
    21241 ctcagcctga aaccaccctc aaaccacagc aaccattaac ttcctatttc caagcagccc
    21301 taactgcact gcgccgcccc gacgctttcc gcccctgccg cctgcataac ctgcgacaaa
    21361 atctgcgtaa gcatattttg agtgatttgt ttaaagaaaa aaccgatgaa gaatgcgaaa
    21421 taaccactgc taacgttatc aataaactca aagcacaaaa cttcatcagc attgatgaac
    21481 aggaaaccgt ttcctaccat ctcagtgata atgatttgtt acaaagaatc caacgccata
    21541 ttttaagcca acgtcccaaa acctacgctg attttcaagc cgtcgtgcaa aaccgagcag
    21601 atgcacttca cttaacagtc ggtaccaacg acattcaatc ctttgcgcga catttgcgcg
    21661 accaaaacct gatccgccaa aacaatggga aaattgaata tgcaccgttt actgaaccta
    21721 aaccacagcc aacacccaag cagcctaaaa aaaccgcatg ggaacctgat gaaattattt
    21781 ggaaaaaagt gattgccgcg ttatcgttaa agaaccgtcc taataaaacc aaaactttac
    21841 gcaatacaat ccaggcactc acaaaatcca atgcacaaga aactgacaaa ctgctacaac
    21901 atttacaaga tacccaagtc ctacgtattg acggtactaa aattgtgtat atcaagtagg
    21961 atgggcattt atgcctgacc tacaaaacca aaaacaacct accaccctta atcaactcca
    22021 caaaccctct tcagacaacc tcgttttttg aaaaacaatc tgtaaacaga taactgctga
    22081 agaataccgt tgccgagccc caaaacctgc ctgcaacttt tattgtgaac ttcccattat
    22141 gaaaaaatcc cttttcgttc tctttctgta ttcgtcccta cttactgcca gcgaaattgc
    22201 ttatcgcttt gtattcggaa ttgaaacctt accggctgca aaaatggcag aaacgtttgc
    22261 gctgacattt gtgattgctg cgctgtatct gtttgcgcgt tataaaactt cgcggctgct
    22321 gattgcgctg tttttcgcgt tcagcattat tgccaacaat gtacattatg cggtttatca
    22381 aagttggatg acgggtatta actattggct gatgctgaaa gaggttaccg aagtcggcag
    22441 tgcgggcgcg tcgatgttgg ataagttgtg gctgcctgcg ttgtggggcg tggcggaagt
    22501 cgtgctgttt tgtagccttg ccaagttccg ccataagacg catttttctg ccgatatatt
    22561 gtttgccttc ctaatgctga tgattttcgt gcgttcgttc gacacgaaac aagagcacgg
    22621 tatttcgccc aaaccgacat acagccgcat caaagccaat tatttcagct tcggttattt
    22681 tgtcggacgc gtgttgccgt atcagttgtt tgatttaagc aagattcctg tgttcaaaca
    22741 gcctgctcca agcagaatcg ggcaaggcag tattcaaaat atcgtcctga ttatgggcga
    22801 aagcgaaagc gcggcgcatt tgaaattgtt tggctacggg cgcgaaactt cgccgttttt
    22861 aacccggctt tcgcaagccg attttaagcc gattgtgaaa caaagttatt ccgcaggctt
    22921 tatgacggca gtatccctgc ccagtttctt taacgtcata ccgcatgcca acggcttgga
    22981 acaaatcagc ggcggcgata ccaatatgtt ccgcctcgcc aaagagcagg gctatgagac
    23041 gtatttttac agtgctcagg ctgaaaacca aatggcaatt ttgaacttaa tcggtaagaa
    23101 atggatagac catctgattc aaccgacgca gcttggctac ggcaacggcg acaatatgcc
    23161 cgatgagaag ctgctgccgc tgttcgacaa aatcaatttg cagcagggca ggcattttat
    23221 cgtgttgcac caacgcggtt cgcacgcccc atacggcgca ttgttgcagc ctcaagataa
    23281 agtattcggc gaagccgata ttgtggataa gtacgacaac accatccaca aaaccgacca
    23341 aatgattcaa accgtattcg agcagctgca aaagcagcct gacggcaact ggctgtttgc
    23401 ctatacctcc gatcatggcc agtatgttcg ccaagatatc tacaatcaag gcacggtgca
    23461 gcccgacagc tatctcgtgc cgctggtgtt gtacagcccg gataaggccg tgcaacaggc
    23521 tgccaaccag gcttttgcac cttgcgagat tgccttccat cagcagcttt caacgttcct
    23581 gattcacacg ttgggctacg atatgccggt ttcaggttgt cgcgaaggct cggtaacggg
    23641 caacctgatt acgggtgatg caggcagctt gaacattcgc gacggcaagg cggaatatgt
    23701 ttatccgcaa tgagtggcgt aaaaaccaat aaagacaaat ttagatgatg tcggggaaga
    23761 tgcccgaccg acaagactat gcaaaatatg aaaaaccaag tacgcggatc aggcatggat
    23821 gcccgatcca acccggccaa tgtttcagac gacctgcaaa acagttcggg ccatatcggt
    23881 gtcaacacgc gttaccgcct gaccaaactc ggcgaacaaa tggcgcgcct gcccatcgac
    23941 ccgaaaatcg cgcgcatttt gctggcggcg aagaaacacg actgcatggc ggaaatattg
    24001 gtgatagcgt ccgcgctgtc gattcaagac ccgcgcgagc ggccgttgga agcgcgcgat
    24061 gccgccgcca aggcacacga gcgttttacc gacaagcaat ccgacttcct tgcctatctg
    24121 aacatttggg acagcttcca gcgcgagcgc gacaaaggtt tgtccaacaa gcagctggtg
    24181 cagtggtgcc gtcaatattt cctgtcgcac ctgaggatgc gcgagtggcg cgagctgcac
    24241 caccagcttg cccaaaccgc gattgaaatg ggtttgacca cgaaagaagc cgctttcaga
    24301 cggcctcccg aaggcaggca gcttacgtcg tctgaaaatg cgggtgacca agacttatcc
    24361 gccaagctca aacaaaaaca actggataaa aagcaacacc gcgcccaaat ccgcgccgcc
    24421 aaagaagcgg gctacgaaca aatccaccgc gccctgctca ctggccttat cgccaacgtc
    24481 ggcatgaaat cgcccgacgg caacgactac accggcgcgc gcggcagccg cttccacctt
    24541 ttccccgcct ccgccctgtt caaagccaag cccaaatggg tgatggcggc agaattggtt
    24601 gaaaccacgc gcctttacgc gcgcgacgtc gccgttatcc agcccgaatg gatagagcag
    24661 gaagcgccgc acctcgtccg ctatcattat ttcgagccgc attgggaaca aaaacgcggc
    24721 gaagtcgtcg ccagcgaacg cgtgacgctt tacggtctga ccgtattgcc gcgccgcccc
    24781 gtgtcttacg gcaaagttgc ccccgaagaa gcgcgcgaaa tctttatccg cagcgcgttg
    24841 gtggcgcagg aatgcgattt gaaagcggat ttttttgtcc acaacaaaaa gctgattaaa
    24901 gaaattaccg aactcgaaca caaatcgcgc aagcaagacg tgctggtcga tgacgaagcc
    24961 ctgtttgcgt tttataacga acggctgccc gatttttata cggcggatgc ggtttcagac
    25021 gacctgcatc ctacaaatcc gcagcaaact gccccctcct acgcgaggga agaacggaga
    25081 gagggcaaaa cagttgccgc acaaaccaac ttctccgcaa ccacagcaaa ccctctccct
    25141 aaccctctcc cacaggaggg ggaacagagt gccgcagctt cagcggtttc aaacgaccct
    25201 caaccccaaa agcagccagc accccaaaaa gaccgtctga aacccctccc cctcgccgac
    25261 atccgcacct tccaagcctg gctcaaaacc gccgaacgcg agaacccgcg cctgctgttc
    25321 ctcagccgcg acgatttgat gcaacacgcc gccgcacaca ttaccgaaga acaattcccc
    25381 aaattctggc aaaccgcaga cggcaagttc gaactcagct accgcttcga gccgcaccac
    25441 ccgctcgacg gcgttaccct caccctgccg cttaccgtgc tcaaccgcat cagccccgcc
    25501 gccctcgaat ggctcgtgcc cggtatgttg cgcgagaaaa tccagctgct gattaaagca
    25561 ctgcccaagc aaatccgccg catctgcgtg cccgtgcccg aattcatcac ccaattttta
    25621 agccaaaacc ccgaccgcaa cgcccccatc ctgccccaac tcgcccaagc catcgccaaa
    25681 accgcaggcg acatccgcat attcgagcaa atcaaccaag acgaatgggc cgcgttcagg
    25741 ctgcccgaac actgctattt caacctccgc atcatcgacg acggcggaca agagcttgcc
    25801 ggcggccgca aactgcatga attgcaacaa cagctcggcc aagccgccgc cgttaccttc
    25861 cgcgacaaca cccaagaatt cgagcgcgac aacgtgacca catgggacat tggcaccctg
    25921 cccgaatcca tcaaattcgc acgcggcaaa caacagctca ccggctacct cggtctgcaa
    25981 aaagaaaaag acggccgcat cgccctgcgc ctgtgtgaca ccaccgaagc tgccgaacag
    26041 gcacaccgtc aaggcgtcat cgaattgatg aagctgcaat taaaagagca ggtaaaagat
    26101 ctgaacaaag gcattcaagg ctttacccaa gccgccatgc tgctcaaaca catcaacgcc
    26161 gacaccctgt gcgacgacct cacccaagcc gtctgcgacc gcgcctttat cggcgaagac
    26221 gagctgccgc gcaacgaaaa agccttcaaa gaacaaatca aacgcgcccg cagccgcctg
    26281 cccgccgtca aagaagccct cagccgctac ttgcaggaaa ccgccgccgc ctacgctgaa
    26341 ctcaacggca aactcggcaa acacccgctc acccatctcc taaaactacg tctgcaaacc
    26401 ctgctcgccg ccggcttcgc cacccgcacc ccgtgggcac aatggccgcg cctccccatc
    26461 tacctcaaag ccatgaccct gcgcctcgaa aaatacagca gcaaccccgc ccgcgacgca
    26521 gcccgcgaag ccgatataca ggaattggaa caaatgtggc aggaaaaaac agacagcctg
    26581 attaaacaag gtctccccat ttcagacggc ctcgccgcgt ttaaatggat gattgaagaa
    26641 ttgagggtgt cgctgttcgc gcaggaattg aagacaccgt atccggtgtc ggtgaagcgg
    26701 ttgttgaaga tgtgggagga tcttaattaa aggaagatgc cgtctgattt tttcagacgg
    26761 catcttttat ttccctgacc aaccgattta atcgctccct accaatagct ttatttttta
    26821 attcgcactc ccaaacgaca atcactttga aaccgatctt ttccagctcg gtttcatttt
    26881 taatatcacg ttcgcaattt tttgtgattt tttccaacca aaaatccgta ttgcttttcg
    26941 ggatatgtcc tttattacaa gaatgcccgt accaaaaaca gccgtgtata aacacgactg
    27001 ttttatattt cggcaaaacg atatccggtt tgcctgcata gcgtttatcg tttttccgat
    27061 aacgaaaacc ttgggagaaa agaaatttcc ttaccaatat ttccggtttg gtttctttgc
    27121 tatggatttt tgacatcacg aaagaacgtt tggatgtagt gaaaatatcg gtcataaatt
    27181 acttggaaga taccaccttc gatcgttttt ttgtctgttc cacttttctt aacaaatacg
    27241 aaaccaagct tattaaatcc aaagcatcct tatcattaaa aatactagga gataaatttg
    27301 ctcttaactc atgttgtaca ggatttctaa atccagtcca tgttccgcat gcaagctgtt
    27361 caagaccatc ttctaaattt tgttccgcct tcgttttgtt attcgttaat agaagtatag
    27421 aatttttact cccgaaagct tgttcaatca attctcttcc gtctatgcta tgaagacctg
    27481 tttgcttctg aaccttattt tcgaaaactt taactgcctc gattgcagca cttaaataat
    27541 ccttcttttc attgtaaaaa tcattacagg cagtatgcaa atcctgatgc aaatgccgcc
    27601 aatgatagta aggatattct ggaataatac tatgtaaggc agagattact tccgcttgct
    27661 ctttatttgt aagctccgaa tcttccaaac gattcaaaat aacttctact ggttcccttt
    27721 ccttttctgg caatttgttt ttccaatttt cgatatcaac cccgctttca cctttcactt
    27781 cgtcatcttt ttcttttttt cttctttttc tccaatcttg cccgatggct cgaacgattt
    27841 ccccaaggaa aacccgtaac tttgaagttt taggatgctt ccaatccaat gatgtcctat
    27901 ctgtagcaat taaatcttca tcatcattat ctataaaatc aatacttaac catcctgtca
    27961 gataggaata gaaatggctg gattcgctat cagtgaaaaa ctcgggcata tttaccattc
    28021 tgccgttggc aaacaaggta atacctttca tattattctt taaaggtttt tccgttgtaa
    28081 tgaacttacc ttgtattaat ccgctgtatt catactgttc gaattttgaa gataacgatg
    28141 aaatattggt tgctagatcc tggtattccc attcgaattg tggggtaaca agatcatatt
    28201 ttagatttcc atcaatgatt ttgggttccg agccgttcaa gcttactttg attttaaaat
    28261 cctgagccgg aaaatcaaac aagcgggaaa gatgctccac ataattatct aacgggtatc
    28321 cttgtttttt cgtcagttcg gttaaagtta tggttgttcc gttttcggta ttgggttcaa
    28381 cagattcttt ctgaaactcc ggttgataaa tacgctcact ttttttaatc tctgcataat
    28441 ccaaagtaaa agtaacccgt tcgtttcctt ggatagtaga aatttcaatt ttgttgccaa
    28501 gcccgaataa tgccaattta ccaaggcctt ttttacccgt tggaattctt ccgcacgggg
    28561 aggcttgttt ttcttccctt ctgttccgac cgattctcaa ataaaaatca ttgatttcat
    28621 cgaagctcat tcctatacca ttatctttaa taacgatttt atgctccggt ttatcgaata
    28681 acctaacttc cacttccgta gcacatgcat cgtaggcatt cgctatcaac tcggcaatcg
    28741 caggaacagt gtgcgaatac atctttacac ccaaatgttc gattacggtt ggctcgaaac
    28801 tcattttcaa tttttcttca gacatgtttt ctccttttct aacattcgat attatcaaca
    28861 attgccctgc ctattttttc cgcatacatc ggaggaacgg cattaccaat caaacgggct
    28921 atcttgtccc tgctgcccgc tttaaagaca tagttacgag ggaacgattg caatgttgca
    28981 ccttcgcgca gtgataacgc cctatcttct tcaggatggg caaacctccc gttggaaata
    29041 ctaaagaatt tggtcgttat ggtaggtgcg ggcttatccc accatagcct accaaacgtg
    29101 tctttaaaac tattgtcttt tccgataaaa cattccagct gtaattcggg aatatgcgca
    29161 aaagccaaac ggtttcctcc gtttttaggt atcaaagcca atcgtttcaa gttgatatca
    29221 gataatcccg cacagctatg cataaaatcc gtttcgtctt ggtgtcctgc aataattttg
    29281 ggaaagccat tttccattcc taaaacatcg cgtaccgtaa gccgtttgcc cgaatacttg
    29341 gctggttcca gcttctcttc ggttattctg tttgcaatta acgtaaatct tttacgactt
    29401 tggggaattc cgtaatcagc cgtattgtga ataccgaaat ggacggtaaa tcctttttct
    29461 tctaataatt ttatgaaatt atcaagcccg ctttctttca tcctgctcag aattcccggt
    29521 acgttctcta caacaacata tccgggatta aaatattcta caaaccgctg aaactccaaa
    29581 agtaaactct tggatttttc cgattttctt ttgtctgttt gaataacact ccaatattga
    29641 caaggactac aacctataag aatcaaatca tcatcattct tttttaaccc gagttctttt
    29701 tccaaggttt caggctgcaa ttcaaaaaca tcagcctgta taaatttggc atttatattg
    29761 gcttcatatg tttctttgca gctgggttcg taatctatcc cggctaaaac ctgaataccg
    29821 gcggattgca ttccatagct cattccacct ccgccacaga aaaaatcaac cgcctttaac
    29881 ttactgtttt tcatttctat ttaaataatt agactagtga gaactaactt tatataacat
    29941 ataatttatt gcttatcaaa aataatttga gattttatta aaattcatgc atctaaataa
    30001 gcagaactta atttcctcca aacgagcgga tgtcttcaaa tgcacacttc acagaaaggt
    30061 cgtctgaaac ccattttcag acgacctttt tccacttccc aaaacaagaa ttcccacccc
    30121 ctccccaaac gtcgcccgaa ccagtaaact ccccatattt caacaacttc ttggaagcca
    30181 accatgcccc gtatccaccc tcctcacctg ttcccgcccc atatcgccga acgcggcctt
    30241 ttgtattttc agcagggcaa ggttcgcgat gtccgaaaaa cttccgccgg gcgttatcgg
    30301 gcctggcgct gtttgctgcc ggcggtctga ataatggtgg cgtcaacgac ggcagcggat
    30361 gctttctcta tttttaagcc tttttcggtc agttg
//
LOCUS       DAXIDM010000012        28118 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000012 DAXIDM010000000
VERSION     DAXIDM010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 28118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28118
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.012"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(150..665)
                     /locus_tag="ACFOAE_000442"
     CDS             complement(150..665)
                     /locus_tag="ACFOAE_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884001.1"
                     /translation="MSAFRKILLIISCLLIASCSFVETIFYMAISPEPVVVDFPLGKK
                     TKRSIELKQKIGKPYAISLGTNFIHYDPKQGERWIDDKLNYPYNISVKIFKVEEDGKK
                     LIIDELLTERSRKLGGGVFGAGGKYSMYIYDFYLPEGEYLFEISDNSEYIPLYDEINN
                     SIRIVVNARIQ"
     gene            complement(926..1483)
                     /locus_tag="ACFOAE_000443"
     CDS             complement(926..1483)
                     /locus_tag="ACFOAE_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FrpA"
                     /protein_id="HFC6884002.1"
                     /translation="MENNKAKSDDNSVSIEFIQDFITASTDVINLSYENFRKNFYTQM
                     STDSTNYAAKHESLGKSVQRELQKTQSQLRQVVRKMQSKYNINNKARAAEISLLRQMQ
                     SQFSRKDVNKNLGNGNTLAQQGSYTKKDGTTAQAGDLLLAADNLHSRLTDKMLSISHV
                     RENTISPFVLGCLKQITINAYHYLK"
     gene            complement(2021..2305)
                     /locus_tag="ACFOAE_000444"
     CDS             complement(2021..2305)
                     /locus_tag="ACFOAE_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884003.1"
                     /translation="MKLALKRSGKYNVYDPLALDLDGDGIETVATKGFSGSLFDHTNN
                     GIRTATGWIAAYDGFSVRKLNSNGGIISTTDTIFQSLHTWLDHQPNDTCH"
     gene            complement(2302..2595)
                     /locus_tag="ACFOAE_000445"
     CDS             complement(2302..2595)
                     /locus_tag="ACFOAE_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated frpA domain protein"
                     /protein_id="HFC6884004.1"
                     /translation="MNIDDFTPSKIANFFADPDTYSNVLEEVSRFIYSLVPDDANPWK
                     GGEDYIGRGISEWGELLEKWYKQDFLPYLEKNGTNFRNLKIGCLNSLNGQESG"
     gene            complement(2934..3155)
                     /locus_tag="ACFOAE_000446"
     CDS             complement(2934..3155)
                     /locus_tag="ACFOAE_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated frpA domain protein"
                     /protein_id="HFC6884005.1"
                     /translation="MTYANFNINGFGDVKLTPYSPLLGYKAWDSFIGSIQSLSDLIYN
                     VDNNRNKMEITVNNAIQAADSFLSSNWKR"
     gene            4178..4354
                     /locus_tag="ACFOAE_000447"
                     /pseudo
     CDS             4178..4354
                     /locus_tag="ACFOAE_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin B"
     gene            4357..4749
                     /locus_tag="ACFOAE_000448"
                     /pseudo
     CDS             4357..4749
                     /locus_tag="ACFOAE_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595-like element ISNme4 family transposase"
     gene            5658..6236
                     /locus_tag="ACFOAE_000449"
     CDS             5658..6236
                     /locus_tag="ACFOAE_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017147256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFC6884006.1"
                     /translation="MHYNPVAYGKIKVQSWKERRDFNIVKQDLDFSCGAASVATLLNN
                     FYGQKLTEEDVLKKLDKEQMPASFEDMRRIMPDLGFEAKGYALSFEQLAQLQIPVIVY
                     LKYRKDDHFSVLRGIDGNTVLLADPSLGHVSMSRAQFLDAWQTREGNLAGKILAVVPK
                     GRDAGGDKAFFTRSPKRQTEFAVGQVKWWRAY"
     gene            6366..8027
                     /locus_tag="ACFOAE_000450"
     CDS             6366..8027
                     /locus_tag="ACFOAE_000450"
                     /EC_number="1.5.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004174 -
                     electron-transferring-flavoprotein dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein-ubiquinone
                     oxidoreductase"
                     /protein_id="HFC6884007.1"
                     /translation="MTESITRDSMQYDVVIVGAGPSGLSAAIKLKQLAEQNGREISVC
                     VVEKGSEAGAHSLAGAVIDPIALNELIPDWKEKGAPLTRTVTQDKVLFLTEKKAFNLP
                     ITPNFDNHGNYIVSLGEVVRWLAEQAENMGVEIYPGFAAAEVLYHEDGSVKGIATGNM
                     GIGKDGEPTDSFQPGMELWAQQTLFAEGCRGSLSKQIIERFKLDQNSQPQTYGLGIKE
                     VWEVPSEQHQPGLVVHSAGWPLDSKTYGGAFVYHFDDNKVAVGFVVGLDYQNPYLSPF
                     EEFQRFKTHPEIRKTFEGGRRIAYGARSLIEGGLQSLPKLSFKGGILVGDAAGFLNMP
                     RIKGIHTAMKSAMLAAEAVFPLLENLEEVEGFDSGKEAADYQQRFEQSWLYQELYAAR
                     NVRPSFKWGVYLGSLYTGIDQMIFRGKAPWTLKHHGKDNEQLKKAAACKPIAYPKPDG
                     VLTFDRLSSVFLANLAHEENQPDHLVLNNPQTMIDVNYKEYASPETRYCPAGVYEIVE
                     ENGNPRLQINAANCVHCKTCDIKDPTQNITWICPEGASGPNYGGM"
     gene            complement(8115..8609)
                     /locus_tag="ACFOAE_000451"
     CDS             complement(8115..8609)
                     /locus_tag="ACFOAE_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase accessory protein NosL"
                     /protein_id="HFC6884008.1"
                     /translation="MKKTLLAIVAVSALSACRQAEEGPPPLPRQISDRSVGHYCSMNL
                     TEHNGPKAQIFLNGKPDQPVWFSTIKQMFGYTKLPEEPKGIRVIYVTDMGNVTDWTNP
                     NADTEWMDAKKAFYVIDSGFIGGMGAEDALPFGNKEQAEKFAKDKGGKVVSFDDMPDT
                     YIFK"
     gene            complement(8606..8737)
                     /locus_tag="ACFOAE_000452"
                     /pseudo
     CDS             complement(8606..8737)
                     /locus_tag="ACFOAE_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688339.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(8754..9368)
                     /locus_tag="ACFOAE_000453"
                     /pseudo
     CDS             complement(8754..9368)
                     /locus_tag="ACFOAE_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709597.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9426..10625)
                     /locus_tag="ACFOAE_000454"
     CDS             complement(9426..10625)
                     /locus_tag="ACFOAE_000454"
                     /inference="COORDINATES: protein motif:HMM:TIGR04247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide reductase family maturation
                     protein NosD"
                     /protein_id="HFC6884009.1"
                     /translation="MASGVYQTKLYIDKPITIEGPADRSATIEGDRSGRTIAVHAPDV
                     TLRNLTITRSGMSLPAMDAGIYLEETAPRALIEHNNILDNSVGVYLHGSADAMVRENK
                     IVGDATLRVNERGNGVTVWNAPGAQVVGNDISKGRDGIFSNTSTHNTYKNNRFSDLRF
                     AVHYMYTNDSEISGNISVGNNMGYVLMFSERLKVFDNIAVGSRDQGIMLNYVNYSDIH
                     DNIINKAGKCVFAYNANYDKLSANHFENCQIGIHFTAAIEGTSLHDNSFINNESQVKY
                     VSTRFLDWSEGGHGNYWSDNSAFDLNGDGFGDSAYRPNGIIDQIIWRAPVLRLLMNSP
                     AISIVKWAQAQFPAVLPGGVVDSKPLMKPYAPKIQTRYQAMKDELLKEAETRQSEWGR
                     AENGSLN"
     gene            complement(10514..11035)
                     /locus_tag="ACFOAE_000455"
     CDS             complement(10514..11035)
                     /locus_tag="ACFOAE_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NosR"
                     /protein_id="HFC6884010.1"
                     /translation="MSCFSIKRMSAFRARITAFFTAFVFLTAALPAYAERLPDFLAKI
                     QPSEIFPGADRYGKPEGKPMVARVYKGDEQLGLVYITTDAVNTRGYSSKPIDTLMALA
                     NDGTIAGAKLVDHHEPIMLIGIPHLPAPGRAIRLNWLPAYIKPNFISTNRLRLKGLPT
                     VPQPSKGTGAAAP"
     gene            complement(11362..12609)
                     /gene="hemA"
                     /locus_tag="ACFOAE_000456"
     CDS             complement(11362..12609)
                     /gene="hemA"
                     /locus_tag="ACFOAE_000456"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008883 - glutamyl-tRNA reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HFC6884011.1"
                     /translation="MQLTAVGLNHQTAPLSIREKLAFTAACLPEAVRNLARSNAATEA
                     VILSTCNRTELYCVGDSEEIIRWLADYHSLPIEEIRPYLYTLDMQETVRHAFRVACGL
                     DSMVLGEPQILGQIKDAVRVAQEQESMGKKLNALFQKTFSVAKEIRTDTAVGENSVSM
                     ASASVKLAEQIFPDIGDLNVLFIGAGEMIELVATYFAAKNPRLMTVANRTLARAQELC
                     DKLGVNAEPCLLSDLPAILHDYDVVVSSTASQLPIVGKGMVERALKQRQSMPLFMLDL
                     AVPRDIEAEVGDLNDAYLYTVDDMVNIVQSGKEARQKAAAAAETLVSEKVAEFVRQQQ
                     GRKSVPLIKALRDEGEKARKQVLENAMKQLAKGATAEEVLERLSVQLTNKLLHSPTQT
                     LNKAGEEDKDLVHAVAQIYHLDK"
     gene            complement(12761..13147)
                     /gene="gcvH"
                     /locus_tag="ACFOAE_000457"
     CDS             complement(12761..13147)
                     /gene="gcvH"
                     /locus_tag="ACFOAE_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005960 - glycine cleavage complex
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HFC6884012.1"
                     /translation="MSSNIPAELKYVASHEWLRLEEDGIITVGITHHAQELLGDIVFV
                     ELPEVGANLAAEEQAGVVESVKAASDVYAPIAGEVVAVNEDLPSAPETANSDPYGAGW
                     FFKLKPANVADYDVLLTAEQYAGEVD"
     gene            complement(13310..14410)
                     /gene="gcvT"
                     /locus_tag="ACFOAE_000458"
     CDS             complement(13310..14410)
                     /gene="gcvT"
                     /locus_tag="ACFOAE_000458"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HFC6884013.1"
                     /translation="MITLKTTPFHQAHQDAGAKPVDFAGWELPIHYGSQIAEHEAVRT
                     DAGMFDVSHMLVTDVAGANAKAFFRKLIANDVAKLAFVGKALYSALLNDNGGVIDDLI
                     VYRTNEAETQYRIVSNGATREKDTAQFHKVGQEFGVSFNPRYDLGMLAIQGPKAIEKL
                     LTVKPEWADVVNNLKPFQGADLGNDWFVARTGYTGEDGVEVILPGTEAVAFFKALQAA
                     GVQPCGLGARDTLRMEAGMNLYGNDMDDDTSPLEAGMGWTVDLKDESRDFVGKAALLA
                     LKEKGVAVKQVGLLLGKGGILRAHMEVLTDKGKGETTSGVFSPSLKQSIAIARVPKDF
                     DGDTAKVLIRGKEADVRVLKLPFVRNGQKQFD"
     regulatory      complement(14621..14718)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            14922..15404
                     /locus_tag="ACFOAE_000459"
     CDS             14922..15404
                     /locus_tag="ACFOAE_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFC6884014.1"
                     /translation="MPQLTLDKTDIKILQVLQENGRLTNVELSERVALSPSPCLRRLK
                     QLEDAGIVRQYAALLSPESVNLGLQAFIRVSIRKAKDAREDFAASVRKWPEVLSCFAL
                     TGETDYLLQAFFTDMNAFSHFVLDTLLSHHGVQDAQSSFVLKEIKHTTSLPLNHLLKE
                     "
     gene            15451..16056
                     /locus_tag="ACFOAE_000460"
     CDS             15451..16056
                     /locus_tag="ACFOAE_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1415 domain-containing protein"
                     /protein_id="HFC6884015.1"
                     /translation="MTIMNINTSENKDAVAEHTGQWLEKAVIGLNLCPFAKAPHVKNL
                     VRIAISEAKHLDSFLEDLDEELQRLGNTPATELETTLLVHPTLFPDFDVFNDMLDIAD
                     AAVVENGLEGIIQIAPFHPDFQFEGTDSDDIGNYTNRSPYPTLHLIREDSIAKAAQAF
                     PDASAIFERNIALLEKMGHEGWVKLGITSCPYPHNKKNISK"
     gene            16053..16412
                     /locus_tag="ACFOAE_000461"
     CDS             16053..16412
                     /locus_tag="ACFOAE_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HFC6884016.1"
                     /translation="MIRYLLIACGGISLLLGIIGIFLPLLPTTPFVLLSAACWAKASP
                     RFHRWLHRHRYFGPMVHNWEQNGAVPRKAKIFAISMMTASCLIMFWQFPQRWWVGAVS
                     SVFCSLVAIWMWRRPES"
     gene            16375..16755
                     /locus_tag="ACFOAE_000462"
     CDS             16375..16755
                     /locus_tag="ACFOAE_000462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate ABC transporter"
                     /protein_id="HFC6884017.1"
                     /translation="MSPYGCGAGPNLECRTERDKGKQTGGKPVSLQIYVKINSFFVFD
                     RLFIKDIYLFVLNKIIYQKEHIFPSTAIRLPAAFRFGKLVYPDYLLYNQSENFFQKQT
                     GSTVRLCPGGTVPVSLPRAAQGSA"
     gene            16770..18191
                     /locus_tag="ACFOAE_000463"
     CDS             16770..18191
                     /locus_tag="ACFOAE_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HFC6884018.1"
                     /translation="MRHLPLFSLMLFPASVYAADLDGANLNLLWSLPFALILLSIALG
                     PLFFSHTWHHHYGKITAFWTLLFLIPFSLVFGASAGIHTVAHALVEEYIPFILLLLAL
                     YTISGGILVWGDLNGTPKLNTALLAVGTALASIMGTTGAAMLMIRPLLKANQNRTRRV
                     HIVIFFIFLVANIGGGLTPLGDPPLFLGFLKGVDFMWTVKHMFAPVLISTAVLLTAFY
                     FIDNRFFKQESIAQDTPAQQEKPEKIAIFGKWNFLLLSGVVGAVLMSGLWKPEHPGFE
                     ILGSRYALQNLVRDVILIALTAVSMAITPKQVRAGNEFNFEPIAEVGKLFLGIFITIF
                     PVLSILKAGEAGALGGVVSLVHDTAGHPINVMYFWMSGILSAFLDNAPTYLVFFNMAG
                     GDAQALMTGTLFHSLLAVSMGSVFMGALTYIGNAPNFMVKAIAEQRGVPMPTFFGYMM
                     WSVAFLTPVFIVHTLIFFVFKLL"
     gene            18539..19882
                     /locus_tag="ACFOAE_000464"
     CDS             18539..19882
                     /locus_tag="ACFOAE_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit A"
                     /protein_id="HFC6884019.1"
                     /translation="MIKIKKGLNLPIAGRPEQVIYDGPAITEVALLGEEYAGMRPSMK
                     VKEGDAVKKGQVLFEDKKNPGVVFTAPASGKIAAIHRGEKRVLQSVVIAVEGNDEIEF
                     DRYAPDALAKLSGKEVRRNLIQSGLWTALRTRPFSKIPAVDAEPFAIFVNAMDTNPLA
                     ADPVVVIKEAAEDFRRGLLVLSRLTERKIHVCKAAGADVPSENAANIETHEFGGPHPA
                     GLSGTHIHFIEPVGANKTVWTINYQDVIAIGRLFATGRLNTGRVVALGGSQVNKPRLL
                     RTVLGAKVSQITAGELVDADNRVISGSVLNGAIAQGAHDYLGRYHNQISVIEEGRSKE
                     LLGWVAPQPDKYSITRTTLGHFLKNKLFKFNTAVNGGDRAMVPIGTYERVMPLDILPT
                     LLLRDLIVGDTDSAQALGCLELDEEDLALCSFVCPGKYEYGPLLRKVLETIEKEG"
     gene            19885..21117
                     /locus_tag="ACFOAE_000465"
     CDS             19885..21117
                     /locus_tag="ACFOAE_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0022904 - respiratory electron transport
                     chain [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit B"
                     /protein_id="HFC6884020.1"
                     /translation="MGLKHFLEKIEPHFLPGGKHEKWYALYEAAATIFYTSGAVTRKA
                     AHVRDALDSKRMMILVWLALFPAMFYGMYNVGAQAFGALTPDLLQQSIANDWHYTLAD
                     ALGINMSSEAGVLGKMLFGAIYFLPIYATVFAVGGFWEVLFATVRKHEINEGFFVTSI
                     LFALIVPPTLPLWQAALGISFGVVVAKEVFGGTGKNFMNPALAGRAFLFFAYPANLSG
                     DAVWTAVDGYSGATALAQWAAHGADGLKNAVTGQTITWMDAFIGKLPGSIGEVSTLAL
                     LIGGAFIVFARIASWRIIAGVMIGMIAMSSLFNFIGSDTNAMFAMPWYWHLVVGGFAI
                     GMLFMATDPVSASFTNVGKWWYGALIGVMCVLIRVVNPAYPEGMMLAILFANLFAPIF
                     DYFVAQANIKRRKARSNG"
     gene            21110..21886
                     /locus_tag="ACFOAE_000466"
     CDS             21110..21886
                     /locus_tag="ACFOAE_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit C"
                     /protein_id="HFC6884021.1"
                     /translation="MAKKFDKDSFSGTLIVVLAVSLICSVIVAGAVVGLKPIQEKQKL
                     QDKQGYILSVAGLMDKDTDIGKTFAERIEQRVVDLATGEYVADAPKDFSARIAGKDPA
                     QSIRIKPEDDLAGIKSRAKYTEVYLVKGEDGKIGQIILPMHGNGLWSVMYGFVAIQPD
                     GNTINGITYYEQGETPGLGGEIGNPLWQQKFVGKKLFDGQGKLALHVGKGAGSDKEHG
                     VDALSGASLTSKGVQGSFAYWFGENGYIPYLNKLKSAGAQ"
     gene            21886..22512
                     /locus_tag="ACFOAE_000467"
     CDS             21886..22512
                     /locus_tag="ACFOAE_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit D"
                     /protein_id="HFC6884022.1"
                     /translation="MADMKRLKHLMFSPFIDNNPIALQVLGICSALAVTTKLQTAIVM
                     GISVALVTGFSSFFISLVRNYIPNSIRIIVQMAIIASLVTLVDQLLQAFAYELSKQLS
                     VFVGLIITNCIVMGRAEAFAMKEPPLESLIDGIGNGAGYGMMLLVVATVRELIGSGKL
                     LGYTVFQTVQDGGWYQTNGLFLLAPSAFFIIGFLIWGLRTWKPEQAEE"
     gene            22516..23109
                     /gene="nqrE"
                     /locus_tag="ACFOAE_000468"
     CDS             22516..23109
                     /gene="nqrE"
                     /locus_tag="ACFOAE_000468"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit E"
                     /protein_id="HFC6884023.1"
                     /translation="MEHYLSLFIKSVFIENMALSFFLGMCTFLAVSKKVSTAFGLGVA
                     VIFVLGLSVPVNQLVYSLLKDGAIVEGVDLTFLKFITFIGVIAALVQILEMFLDKFVP
                     ALYNALGIYLPLITVNCAIFGAVSFMAQREYNFGESVVYGFGAGLGWMLAIVALAGIT
                     EKMKYSDAPKGLKGLGITFIAAGLMAMAFMSFSGIQL"
     gene            23123..24340
                     /gene="nqrF"
                     /locus_tag="ACFOAE_000469"
     CDS             23123..24340
                     /gene="nqrF"
                     /locus_tag="ACFOAE_000469"
                     /EC_number="7.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:ubiquinone reductase (Na(+)-transporting)
                     subunit F"
                     /protein_id="HFC6884024.1"
                     /translation="MEIILGIVMFTVIVLVLALMILFAKSKLVSEGDITIKVNGEKEL
                     TMPAGGKLLGALANEGIFIPSACGGGGSCGQCRVVVKSGGGDILPTELSHISKREARE
                     GCRLSCQVSVKTDMDIEVPEEVFGVKKWECTVISNDNKATFIKELKLAIPEGEEVPFR
                     AGGYIQIEAPPHTVAYKDFDIPKEYHEDWDKYNLWQYVSKVDEPILRAYSMASYPEEK
                     GIIMLNVRIATPPPRVPDAPPGQMSSYIWSLKPGDKVTISGPFGEFFAKDTDAEMVFI
                     GGGAGMAPMRSHIFDQLKRLNSKRKITFWYGARSKREMFYVEDFDQLAAEFPNFTWHV
                     ALSDPLPEDNWDGYTGFIHNVVYENHLKNHEAPEDCEFYMCGPPIMNQSVIKMLKDLG
                     VEDENILLDDFGG"
     gene            24865..25002
                     /locus_tag="ACFOAE_000470"
     CDS             24865..25002
                     /locus_tag="ACFOAE_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884025.1"
                     /translation="MPSEHPSDGIGIETYRPFCDIIQTICQNRQTLCRLKHACRTLSA
                     P"
     gene            24960..26015
                     /locus_tag="ACFOAE_000471"
     CDS             24960..26015
                     /locus_tag="ACFOAE_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFC6884026.1"
                     /translation="MPSETRLPNFIRTLIFALSFIFLNACSEQTAQTVTLQGETMGTT
                     YTVKYLSNNRDKLPSPAEIQKRIDDALKEVNRQMSTYQPDSEISRFNQHTAGKPLRIS
                     SDFAYVTAEAVRLNRLTHGALDVTVGPLVNLWGFGPDKSVTREPSPEQIKQAASYTGI
                     DKIILKQGKDYASLSKTHPKAYLDLSSIAKGFGVDKVAGELEKYGIQNYLVEIGGELH
                     GKGKNARGEPWRIGIEQPNIIQGGNTQIIVPLNNRSLATSGDYRIFHVDKSGKRLSHI
                     INPNNKRPISHNLASISVVADSAMTADGLSTGLFVLGETEALKLAEREKLAVFLIVRD
                     TGGYRTAMSSEFEKLLR"
     gene            26041..26256
                     /gene="nqrM"
                     /locus_tag="ACFOAE_000472"
     CDS             26041..26256
                     /gene="nqrM"
                     /locus_tag="ACFOAE_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Na+)-NQR maturation NqrM"
                     /protein_id="HFC6884027.1"
                     /translation="MKTLLLTFGIFLTVIIGMAVGYIFSKRTIKGSCGGITALGMKKM
                     CDCDTPCDTLQKKLDEEKQAGGIRVDR"
     gene            complement(26380..26958)
                     /gene="grpE"
                     /locus_tag="ACFOAE_000473"
     CDS             complement(26380..26958)
                     /gene="grpE"
                     /locus_tag="ACFOAE_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFC6884028.1"
                     /translation="MSEQTQQQNSEEAVENVEAVETVETVGNADGVQEQAAAEPAYED
                     LQARIAELEAQLKDEQLRALANEQNLRRRHQQEIADTHKFAGQKFAVEMLPVKDYLEM
                     ALLDQSGNFDALKMGVQMTLNELQKAFDATQIKEINPKAGDKLDPNIHQAMQAVASEQ
                     EPNTVVGVMKKGYTLSDRVLRPAMVTVAQKEA"
     gene            27142..27960
                     /gene="cysE"
                     /locus_tag="ACFOAE_000474"
     CDS             27142..27960
                     /gene="cysE"
                     /locus_tag="ACFOAE_000474"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFC6884029.1"
                     /translation="MKKDHLNTTGFDLWHTIREETAAAVSAEPMLASFLHQTVLRHES
                     LGSVLAYHLSSKLGSPIMDVRALFEIYQQALGSDTQIGKCVEADLKAIYERDPACDEY
                     SLPLLYFKGFHAIQAHRINHRLYLDGRKTLAYFLQNRMSEVFGVDIHPAARFGYGLML
                     DHATGFVAGETAVLGNNISILHGVTLGGSGKEGGDRHPKIGDGVMIGANASILGNIRI
                     GSNAKIGAGSVVVSDVPPSITVVGVPAKPVARSLKTPSADMDQNIQFAEIDFMI"
BASE COUNT         7085 a         7211 c         6551 g         7271 t
ORIGIN      
        1 atttttttat ctctagccga atacagttca acccaaacgt acccgtcttg gatacacccc
       61 ctcttgtttc agtggcgtac cctgcttcgc aaattttaca gttatcgcat aataatcagc
      121 cataagtaac cccacatttc tagaaaaatt tactgaattc gtgcattaac tactattctt
      181 atagaattat ttatttcatc gtaaagtgga atatattcac tattatcaga aatctcaaat
      241 aaatattccc cttccggcaa ataaaaatca taaatataca tactgtattt tcccccagct
      301 ccaaatactc cgcctcctaa ttttctactt ctctctgtaa gcaactcatc tataataagt
      361 tttttaccat cttcttccac tttaaatatt ttaaccgata tattatatgg atagtttaac
      421 ttatcatcaa tccacctctc cccctgtttt ggatcataat gtataaaatt agttcctaac
      481 gatattgcat aaggtttacc aattttctgt ttgagttcaa tagatctttt tgttttttta
      541 ccaagaggaa agtctaccac aacaggttct gggctaatag ccatataaaa aatagtttca
      601 acaaaactgc agctagcaat caataggcaa gatattatta ataatatttt tctaaatgca
      661 gacataataa aaatttccaa aaaatccata tcagaatata ctaattattt gtataattaa
      721 taaggaagag aaaaattcaa aacggctatg agatttccgc ctgaaaataa tgaaataaaa
      781 gtccatagta atgaataata gctttatcag acccccttta atgcaaacat agagaatact
      841 tcccttgaag cactatcaat ttctacttaa ctaaaactct agctctattt ctaaaatttt
      901 gtcaaaaata gttaaatact tttatttatt ttaaataatg atatgcattt atggttattt
      961 gttttagaca gcctaaaaca aacggggaaa tcgtgttttc ccgaacatgg ctaatggata
     1021 gcattttgtc cgtgaggcgg ctgtgcaggt tgtcagcagc caacagcaaa tcgcctgctt
     1081 gcgcggttgt gccgtctttt ttggtgtagc tgccttgttg agccaaagtg ttgccgttac
     1141 caagattttt gtttacatct tttcgagaaa attggctttg catttgcctt aacaaagata
     1201 tttctgctgc tcgtgcttta ttatttatat tatatttact ctgcattttt cttacaactt
     1261 gtctcaactg actttgtgtt ttttgtaatt cacgttgtac cgattttcct aaactttcat
     1321 gtttggctgc ataattggta gaatcagttg acatttgtgt ataaaaattt ttacgaaaat
     1381 tttcgtaact cagattaatt acatccgtac ttgcagttat aaaatcttgt ataaattcaa
     1441 tagaaactga attatcatca gatttggctt tgttattttc catattaagc ctctcttaat
     1501 ttgaaaaaat taacataaac atttaaaaat aaaacaaaat tatataataa aaaaaataat
     1561 gagaatataa aggataaaaa gagagttaag ttatttaatc ggacttgttc tctataaatc
     1621 ataaggcacc aaataagcca taataaattt agtaaataaa aactgcttat acccaacttt
     1681 cttttcttgg aacctattat tatttcaact ctggatgaaa aaatagaatt taaaaatttt
     1741 tttctttgat atatcgttaa tatctcccta gtttttctta aaaaaaatat aatcatatat
     1801 atactacaca acattggtaa taaataaatt aaaagcgaaa ggtaattaaa ttgataattg
     1861 taaattatat aataaacaac atacgaagaa aaaattatta tagatgattt actatacgaa
     1921 taaaaaaata tcctacctag cccgaacctt cttataattt gtactatgtg atcattcatt
     1981 tcaatatcca tttaagcttt caattaattt tctatatttt tcaatggcat gtatcatttg
     2041 gttgatgatc aagccatgta tgcaaagatt ggaatatggt atctgtcgtg ctaataatgc
     2101 ccccgttact gtttaatttg cgcacagaaa aaccgtcata tgcagcaatc cagcccgtgg
     2161 cggtgcggat gccgttgttg gtgtgatcaa ataagctgcc tgaaaagcct ttggtggcaa
     2221 cggtttctat accgtcgccg tccaaatcta gggcgagggg atcgtaaacg ttatatttgc
     2281 ctgaacgttt gagagctaat ttcaaccact ctcttgccca ttcagggaat tcaggcagcc
     2341 aatcttcaaa tttcggaaat tggtcccatt cttttcaaga taagggagaa aatcttgttt
     2401 ataccatttt tccagtaact ctccccattc acttatccct cgtccaatat aatcttcgcc
     2461 ccctttccaa gggtttgcat catcaggaac taaggaatat ataaacctag atacttcttc
     2521 taatacattg ctgtatgtat caggatccgc aaaaaagttt gctatcttac ttggtgtaaa
     2581 atcatctata ttcattatag attcgccaag cctctcgttt ccataatcct tatttaattc
     2641 aattcatgct gtaaaacagt agaggatttt agcattctag aattaaggac atcatttaaa
     2701 ccagttttta atttagttgg taagaatttg ctttgagcca tcgcctctgt ttgttgtttt
     2761 atatattgta atctatcacc agcagcaatg aatatatcac caatttcttg ttgaatatca
     2821 ttaggtttaa attttcctgt ttctcgtata tctcgagata catttcttaa atttaaaaaa
     2881 atgttatcga gggatgcaag taaagaagca gtatttgtta ttttgttatt ttgttatctc
     2941 ttccaattac tgcttaaaaa gctatctgca gcttgaatag cattattaac agtaatttcc
     3001 attttatttc tattgttatc cacattatag attaaatcag ataaggattg aatagaacca
     3061 ataaatgaat cccaagcttt atatcccaag agtggtgaat agggtgttaa tttcacatct
     3121 ccaaaaccgt taatattaaa atttgcatat gtcatatctg ctttcctttc aagtaaatta
     3181 aaaaaataac gtgaggaatt aaaattaaaa ataaattaat tatcgactca atataatatg
     3241 aatcaattag ctctcttatg gtaaatataa gaggtaaaaa tactaaaaat aaactaataa
     3301 agttcagaaa aatagtaaat ggaatatttt catatggaaa aattctacaa aatacaagta
     3361 atattccatg acatattaac aaatgagtaa aattcattat aaaatatata aatatttccc
     3421 catcgtaaga tatattcaaa taaagacata taaacaatat aaagtatata aaatatattt
     3481 tttggcatct aaaaaataaa cttttagcaa tcatatatga atagcttgta gaatagaaaa
     3541 cgaaaattat taattatcgt aggtgtgcat ttattccaac acggtttcat gcagcttaaa
     3601 aaccagaaat tctttctccc tttatccttt cttaaaaata gcgtttccaa attctgcaac
     3661 gacaggtttc attcaagtag gactgccgtg attgcatcaa ttgcttcgcg gcatggcatc
     3721 catatcacac aacaggacat ttattctcgg gtaagtccac cttcatcctc ttcggccagc
     3781 aggaacagta aaatatgctc tgtactcgga tagtaaatat ttcctttctc actattgttt
     3841 gtcatttaat cgacagtcta ctctttctct aaaatttcgt caataatagt taaatatatt
     3901 taaatacatt taaaataata atatacacct gtttcagtct gtctaaaaca cgggaaaata
     3961 tgttatttga tcacaacggt gactttgggc agcctgtacc ttcaataacg cgtggaaaat
     4021 agatatatac ttatatcgta ttcgaggctg tcttgtttcc ctcaaacaac cattcttcca
     4081 cacttttgct ttacaatttt cgtgtgtatc cttacaatta cccctattgt ttttgtatat
     4141 tcctttgcca accgttattg ctatccaatc taatattatg gctatcgtat ctacaccaca
     4201 ccccgctctt tccgccctca tcatcctcgc ccattatcac ggcattgccg ccaaatcttt
     4261 gggattgaag gcaaaggtag tacgccagcc tgtcaaacgt ttggctatgg tgaccttacc
     4321 tgcattggta tggtgtgatg acggcaacca ttttaaggaa aagtggttgt tttcggcatt
     4381 ctgaaacgca acggacgggt ctataccgtt gtggtggata atgccaagtc tgaaacgtta
     4441 ctccctgtca tcaaaaagaa aatcatgccg gacagcattg tttataccga tagtctgagc
     4501 agctacgaca agttggacgt gagcggtttt atccattacc gcatcaacca ttccaaggag
     4561 tgtgcagacc gtcaaaacca cattaacggc attgagaact tttggaatca ggcaaaacgc
     4621 gtcttgcgaa aatacaatgg aatcgatcgc aaatctttcc cgctgttctt gaaagaatgc
     4681 gaatttcgat ttaacttcgg cacaccgtct caacagctta aaatcctgcg ggattggtgt
     4741 gggatttagg gctaatctag tacagcccct tagatttaat tcactatacc tgcgtaatgg
     4801 tatcgggtac tcatcatcaa cctgccttgc attcggttgt gttgtccggc aactgtccgg
     4861 ttgtgtcgat gggttgccct gccgctccct gtgctgcgca acggttgtgt gccttgggtg
     4921 ggcgcgggtg gcggccgggc ggtttgttgc tatgatacgg gagttccgat atacaagggt
     4981 gggcttcagc ccaccaatca acgaccgaaa aagaaaaaac gttgggctga agcccactct
     5041 acgcaattac gcaactgtta tcgtggggat gacgggattt taggtttttg tttttctgtt
     5101 tttgcgggaa ggatgggttt taggttgcgg tcatttatcg gaaaagcaga aatcgctccg
     5161 ccgtcattcc cgcgaaagtg ggaatctgaa cacgtccgta gggaaaccta tatcccgtca
     5221 ttcccacgaa agtgggaatc tagaacctct gaattttcag acaacctttg aatattgccg
     5281 ccgtcccgcg ttctagattc ccgcctgcgc gggaatgacg attcatcagt ttcccgaaac
     5341 gcccgaaaaa ccgaaaccga gcaaaccgga ttcccgcctg cgcgggaatg acgatttata
     5401 agtttcccga aacacccaaa aaaaccgaaa tccgacaggc aggatttttg ctttcgtggg
     5461 gatgacggga ttttaagtta cggtcattta tcggaaaagc agaaactgct ccgccgttat
     5521 tccagcgaag gcgggaatct gaacacgtcc gcacggaaac ctatagtgga ttaacaaaaa
     5581 tcaggacaag gcgacgaagc cgcagacagt acaaatagta cggcaaggcg aggcaacgcc
     5641 gtactggttt aaatttaatc cactataatc ctgttgctta tggaaaaatc aaagtgcaga
     5701 gttggaaaga gaggcgcgat ttcaatattg taaagcagga tttggatttt tcctgcgggg
     5761 cggcttcggt ggcgacgctt ttgaacaatt tttacgggca aaagctgacg gaagaggacg
     5821 tgttaaaaaa actggataag gagcagatgc ccgcgtcgtt tgaggatatg cggcgcatta
     5881 tgcctgattt gggttttgaa gcgaaaggct atgccctgtc tttcgagcag cttgcacagt
     5941 tgcaaatccc cgtcatcgtg tatctgaaat accgcaagga tgatcatttc tcggtattgc
     6001 gcggtataga cggcaatacg gttttgcttg ccgacccgtc gctgggtcat gtttcgatga
     6061 gcagggcgca gtttttggat gcttggcaaa cccgtgaggg aaatttggca ggtaagattt
     6121 tggcggttgt gccgaaaggg agggatgccg gcggggataa ggcgtttttc acacgcagtc
     6181 cgaaacgtca gacggagttt gcggtcggac aggtaaaatg gtggcgtgct tattgaaatt
     6241 tcgacaaagg tcgtctgaaa accgaaaata tggttttcag acgacctttg ttgtatttgg
     6301 taactatatg ttcccgttgt ataattacgg atttgcaatt caataataaa tacacaggaa
     6361 ccgccatgac agaatccatc acccgcgaca gtatgcaata cgatgtcgtg attgtcggcg
     6421 caggcccgtc gggtttgtcc gccgccatca aactcaagca gcttgccgaa cagaacgggc
     6481 gcgaaatcag cgtttgcgtg gtggagaaag gttcggaggc gggtgcacat tcgctggcgg
     6541 gcgcggttat cgatccgatt gcgctgaatg agttgattcc cgactggaaa gaaaaaggcg
     6601 cgccgctgac gcgtacggta acgcaggaca aagtgttgtt cctgactgag aaaaaagcgt
     6661 tcaatctgcc tattacccca aatttcgaca atcacggcaa ctacatcgtc agcttgggcg
     6721 aagtcgtgcg ctggttggcg gagcaggcgg aaaatatggg cgtggaaatc tatccgggct
     6781 ttgccgccgc cgaagtgctg tatcacgaag acggttcggt caaaggcatt gcaaccggca
     6841 atatgggcat tggcaaagac ggcgagccga ccgattcatt ccaacccggc atggagcttt
     6901 gggcgcagca aaccctgttt gccgaaggtt gtcgcggttc gctttccaaa caaatcatcg
     6961 aacgcttcaa actcgaccaa aacagccagc cgcaaactta cggcttgggc attaaagaag
     7021 tttgggaagt gccgtccgaa cagcatcagc ccggtttggt ggtgcacagc gcaggctggc
     7081 cgctggacag caaaacctac ggcggcgcgt ttgtttacca tttcgatgac aacaaagtcg
     7141 ccgtcggctt cgtggtcggt ttggactatc aaaatcctta tctgtcgccg tttgaagagt
     7201 tccaacgttt caaaacccat cccgaaatcc gcaaaacctt tgaaggcggc cgccgcattg
     7261 cttacggcgc acgttcgctg attgaaggcg gtttgcaaag cctgccgaaa ctctcgttca
     7321 aagggggcat tttggtcggc gatgcggcgg gtttcctcaa tatgccgcgc atcaaaggca
     7381 ttcataccgc gatgaaatcc gccatgctcg ccgccgaagc cgtgttcccc ttgttggaaa
     7441 accttgaaga agtggagggt ttcgacagcg gcaaagaggc ggcggattat cagcaacgtt
     7501 ttgaacaaag ctggctgtat caagagcttt acgccgcgcg caacgtccgt ccgtcattca
     7561 aatggggcgt ttacctcggc tcgctttata ccggcatcga ccagatgatt ttcagaggca
     7621 aagccccgtg gaccttgaaa catcacggta aagacaacga gcagctcaaa aaagccgccg
     7681 cgtgcaagcc gattgcttat ccgaaacccg atggcgtgtt gaccttcgac cgcttgagca
     7741 gcgtcttcct tgccaatctc gcgcacgaag aaaaccagcc cgaccatttg gtgctgaaca
     7801 atccgcaaac gatgatagac gtgaactaca aagaatacgc ctcgcccgaa acgcgctatt
     7861 gtccggcggg tgtgtacgaa attgttgaag aaaacggcaa tccgcgcctg caaatcaacg
     7921 cggcaaactg cgtgcactgc aaaacctgcg acatcaaaga cccgacgcaa aacatcactt
     7981 ggatttgccc cgaaggcgcg agcgggccga attacggcgg gatgtgaagg ttctttcctg
     8041 ccgacactat accgaacaag aaaagaaaaa ccgaccgaaa ctcgttttta aagtttcggc
     8101 cggttttttc aatattattt gaaaatatag gtatcaggca tatcgtcgaa actgacaacc
     8161 ttaccgcctt tatcctttgc aaatttttca gcctgctcct tgttgccgaa cggtagcgcg
     8221 tcttccgcac ccataccgcc gataaagccg ctgtcgatga cgtaaaaggc ttttttcgca
     8281 tccatccact ccgtgtcggc attgggattc gtccaatcgg taacattgcc catatcggta
     8341 acgtaaatca cgcggatgcc tttaggctct tcgggcagct tggtatagcc gaacatctgc
     8401 ttgatggtgg agaaccaaac gggctgatcg ggtttgccgt tcaagaaaat ctgggctttg
     8461 gggccgttgt gttcggtcag gttcatactg caatagtgtc cgaccgaacg gtcgctaatc
     8521 tgccggggta aaggcggcgg cccctcttcc gcctgccggc aggcacttaa ggcggaaacg
     8581 gcaacaattg ccaacagggt ttttttcata tttgtcgctt tctaaaaatt ccggctgcca
     8641 aaacaagcgg aatgataacc cataaaacct gagcggtcag caaaacgggg acggtcaggc
     8701 tgatttgtcc gctcaaaccc gccatacccg catatagtgg attaaattta atccacgata
     8761 atgcggtcgg cgtgcccgtc caactcggca agggcgtggg tgctgagcaa tacggtcgcg
     8821 ccgcgcccgt tgagttcgcg cacgacttcg taaaacattt gtcgtgatgc agggtcgagg
     8881 ccggttgtcg gttcgtcaaa cagcaggact ttgggctcgc ccagcagggc ttgtgccaag
     8941 gcaaggcgtt ggcgcatccc tttagaataa gtgccgacgc ggcggtgtgc cgcctgtgaa
     9001 ataccgacac gctcaagcag cccccggttc tgcgtgagcg gctgtttttt aagtttggca
     9061 taaaaatcca gcgtttcgat gccggtcagc gaagggggca gcgcaacggt ttcgggcagg
     9121 tagccgattt ggctgcgaag ccgcaccccc gctttgctac cggtacgttc gcccaaaagc
     9181 atcacttcgc cttcggtcgg ggtaatcagc ccgagtatca gcttcataat ggtggacttg
     9241 cccgcgccgt tgtgtccggc aagcccgacg ctttctcctg ccttcaaaac caaatcaact
     9301 tggttgaccg ctttttgcgc cccgaaccgt ttggttacat tcctcaattc gacatgatgt
     9361 gtggtcatgg tttttccttt tgtgttttca gacggcattt gaatccggat gccgtctgaa
     9421 acagactagt tcaaagaacc gttttccgcc ctgccccatt ccgactgccg cgtttcggct
     9481 tctttgagca actcgtcctt catcgcctga taacgggttt gaattttggg ggcataaggc
     9541 ttcatcagcg gtttgctgtc caccacgccg ccaggcagaa cggcgggaaa ctgcgcctgc
     9601 gcccatttga cgatgctgat tgcgggactg ttcatcaaga ggcgcaatac gggcgcgcgc
     9661 cagatgattt ggtcgatgat gccgttgggc cggtacgcgc tgtcgccgaa gccgtcgccg
     9721 ttcaaatcga acgcactgtt gtcgctccaa tagttgccgt gtccgccctc gctccagtcg
     9781 agaaagcgcg tgctgacgta tttgacctgg ctttcgttgt tgataaagga attgtcgtgc
     9841 agagacgtgc cttcgatggc ggcggtaaag tgtatgccga tttggcagtt ttcaaaatga
     9901 ttggcggaca gtttatcgta gttggcattg taggcaaaaa cgcacttgcc cgctttgttg
     9961 ataatgttgt cgtgaatatc ggaatagttg acatagttga gcatgatgcc ttggtcgcgg
    10021 ctgccgacgg cgatattgtc aaacactttg agccgctcgg aaaacatcag cacatagccc
    10081 atattgttgc ccacggaaat attgccgctg atttcgctgt cgttggtgta catatagtgg
    10141 acggcgaaac gcaaatcgct gaagcggttg tttttatagg tgttgtgcgt gctggtgttg
    10201 gaaaaaatgc cgtcccgccc tttggaaatg tcgttgccga cgacctgcgc accgggtgcg
    10261 ttccaaacgg taacgccgtt gccgcgctcg ttcacgcgca aagtcgcgtc gccgacgatt
    10321 ttattctcgc gcaccatcgc atcggcagaa ccatgcagat atacgccgac cgaattatcc
    10381 aaaatattgt tgtgttcaat cagggcgcgc ggggcagttt cttcgagata aataccggca
    10441 tccattgcgg gcaggctcat accggaacgt gtaatggtca ggttgcggag cgttacgtcc
    10501 ggcgcgtgta cggctatggt gcggccgctc ctgtcccctt cgatggttgc ggaacggtcg
    10561 gcaggccctt caatcgtaat cggtttgtcg atataaagtt tggtttgata tacgccggaa
    10621 gccagtttaa gcgtatcgcc cgcccgggcg cgggcaaatg cgggataccg atcagcataa
    10681 tcggttcgtg atgatcgacc agtttcgctc cggctatcgt gccgtcattt gccaaagcca
    10741 tcagcgtatc gatcggtttg ctcgaataac cgcgcgtatt gaccgcatcg gtcgtgatat
    10801 agaccaagcc caactgctca tcgcctttgt aaacgcgggc aaccataggc ttgccttccg
    10861 gcttgccgta acggtccgca cccggaaaaa tttccgaagg ctgtattttc gccagaaaat
    10921 caggcagacg ctccgcataa gcgggcagtg ccgccgtcaa aaagacaaag gcggtaaaaa
    10981 acgctgttat ccgcgcccga aacgcggaca tacgtttgat tgaaaaacag gacatgacta
    11041 tccccgatat accgatactc tttaatattg atattatatg aatcatctat cggcgatttt
    11101 ttgatgcaaa tcaaatttac aaatcttaaa accaatccgc atacgggata atatagtgga
    11161 ttaaatttaa accagtacag cgttgcctcg ccttgccgta ctatctgtac tgtctgcggc
    11221 ttcgtcgcct tgtcctgatt tttgttaatc cactatactt tgtgattaca tcgatataat
    11281 gtgggatttc acgatgttgt caggcggcac aaaaatatgc cgtctgaaac ctcttcagac
    11341 ggcatttttc ccagcgcacc gttatttgtc caaatgataa atctgcgcga cggcgtgaac
    11401 caaatcctta tcttcttccc ccgccttatt caaagtttgg gtcggcgaat gcagcagctt
    11461 gttggtcagt tggacggaca gccgttccaa aacctcttct gccgttgcgc ctttagcaag
    11521 ctgtttcatc gcattttcca acacctgctt gcgcgctttc tcgccctcgt cccgcaaggc
    11581 tttaatcaag gggacgctct tcctgccctg ctgctgccgg acaaattcgg caaccttctc
    11641 ggacaccagc gtttcagcgg cggcggcggc cttctgcctt gcctccttgc cgctttggac
    11701 gatattgacc atatcgtcca ccgtataaag ataggcatcg ttcaaatcgc cgacttccgc
    11761 ctcaatgtca cgcggcacgg ccaaatcaag catgaacaac ggcatactct gcctttgttt
    11821 caatgcacgc tccaccatgc ctttgccgac tatcggaagc tggctcgccg ttgaagaaac
    11881 caccacgtcg taatcgtgca gaatggcagg cagatcggac agcagacacg gttcggcgtt
    11941 aacaccgagc ttgtcgcaca actcctgtgc acgcgccagc gtccggttgg caaccgtcat
    12001 caatctgggg tttttagcag caaaataagt agcaaccaac tcaatcatct cacccgcacc
    12061 gataaacaag acattcaaat cgccgatgtc ggggaaaatc tgctctgcca acttgacgga
    12121 agcggaagcc atggaaaccg agttctcgcc gacagcggta tcggtacgga tctctttagc
    12181 aacggaaaag gttttttgga acagggcatt gagtttctta cccatacttt cctgctcttg
    12241 agcaaccctg accgcatcct taatctgtcc taaaatctgc ggctcgccca acaccatcga
    12301 atccagcccg caggcaactc ggaaggcatg gcgcacggtt tcctgcatat ccagcgtgta
    12361 cagatacgga cggatttctt caatcggcaa actgtggtaa tcggcaagcc atcggatgat
    12421 ttcttccgaa tcgccgacgc agtaaagctc ggtgcggttg caggtagaaa ggattaccgc
    12481 ctccgttgcc gcattgcttc gggcaagatt gcggacggct tcgggcaggc aggccgcggt
    12541 aaacgccagc ttttcccgta tgcttaaagg tgcggtttga tgattgagtc cgacggcggt
    12601 aagttgcatg aaaaaatcgg taaagatgaa tataggccgt tattatagcc taactgcttc
    12661 cttaaaacac ggacaaaaaa ctgcacctcc gaccgcaaaa atgccgtctg aaggtgcagt
    12721 ttccgtttgt ccggcggttg ccatcgggca gccgggcggt ttaatccact tcgcccgcgt
    12781 attgttcggc agtcagcaga acgtcgtaat cggcaacgtt tgccggtttg agtttgaaga
    12841 accagcctgc accgtaagga tcgctgttgg cagtttccgg agcgcttggc aaatcttcgt
    12901 tgacggcaac gacttcacct gcaatcggtg cgtacacgtc ggacgcggct tttacagact
    12961 caaccacacc ggcttgttct tcggcggcaa ggtttgcgcc gacttcaggc agctcgacaa
    13021 acacgatgtc gcccaacagc tcttgcgcgt ggtgggtaat accgacggtg atgataccgt
    13081 cttcttcaag gcgcagccat tcgtggctgg caacgtattt cagttctgcc gggatgttgc
    13141 tgctcatggt ttgatactcc attgataggg ggttattttc agacggcatc tgcatgaatc
    13201 aatatccaca gatgccttgt tcaatgcttt ctacaaacgt ccgtatcgga cgacaattaa
    13261 aacctgcttt cagacggcat atgaaatgaa aatgccgtct gaaccgatat taatcaaact
    13321 gtttttgacc gttgcggacg aacggcagct tcagtacgcg cacgtccgct tccttgccgc
    13381 gaatcagcac tttggcggta tcgccgtcaa aatctttcgg tacgcgggcg atggcgatgg
    13441 attgtttcag acttggagag aatacgccgc tggtggtttc gcctttgcct ttgtcggtca
    13501 acacttccat atgcgcgcgc aggatgccgc ctttgccgag cagcaaaccg acctgtttga
    13561 cggcaacgcc tttttctttc aatgccaaca aggcagcttt gccgacaaaa tcgcggcttt
    13621 cgtctttcaa atcaacggtc caacccatgc ctgcttcgag cgggctggta tcgtcgtcca
    13681 tatcgttgcc gtagaggttc atgccggctt ccatgcgcag ggtgtcgcgc gcgccgagac
    13741 cgcaaggttg tacgcctgct gcttgcaggg ctttgaagaa tgcgacggct tcagtgcccg
    13801 gcagaatcac ttcgacgccg tcttcgccgg tatagcctgt acgggcgaca aaccagtcgt
    13861 tgcccaaatc cgcgccttgg aacggtttga ggttgttgac gacatccgcc cattcgggtt
    13921 tgacggtcag gagtttttcg atggctttcg ggccttgtat ggcaagcata ccgaggtcgt
    13981 agcgcggatt gaaggaaaca ccgaactctt gtccgacttt gtggaattgc gccgtgtctt
    14041 tttcgcgagt cgctccgttg gacacgatgc ggtattgggt ttcggcttcg ttggtgcggt
    14101 aaacgattaa gtcgtcaatc acgccgccgt tgtcgttgag caaagcggaa taaagggctt
    14161 tgccgacaaa agcgagcttg gcgacatcgt tggcaatcaa tttgcggaaa aaggctttgg
    14221 catttgcgcc tgctacgtcg gtaacaagca tatgggatac gtcaaacata ccggcgtcgg
    14281 tgcgcacggc ttcgtgttcg gcgatttgcg aaccataatg gatgggcagc tcccagccgg
    14341 caaaatctac cggcttcgcg cctgcatctt gatgggcttg atgaaatggg gtggttttca
    14401 gagtaatcat tctcaagttt ctccggattt tttgttcaga tgccacccgc gcacctgtgc
    14461 gcggatgacc ctatctgtcc ttgaacctga gattttcggc cgtatccgca tgatggcaaa
    14521 ccagtctgct cactgctttg cgcggttgtc tgaatggtgg ttcagacggc cttctcccct
    14581 tcggtggacg ttattccaac gccgctctcc agattgtttg tttcaatgtg cagtccctga
    14641 tacctgagcg atttaagggt gtctgcgcct tcggtggtta cattgtagtt gggtgtaaca
    14701 ctctcctgca catttcccga ttatgtcttg aatcggcggt ttgggcaagc cgtcttaaaa
    14761 gagatgcaaa ccgaccgcct ctgttttcac atgattttcc gaaaacaaaa tttgtcccgg
    14821 atgacggtat aactttttat atgttaatat ggtctccatc tgtgcggatt gccgcaaaca
    14881 tacggacaga caatccgaat tccttaaaac ggaacgcaaa tatgccccaa ctcactttag
    14941 acaaaaccga tattaaaatc ttacaggttc tccaggaaaa cggcaggctg accaatgtcg
    15001 aactgtccga acgtgtcgca ctttcgcctt ctccgtgcct gcgccgtctg aagcagttgg
    15061 aagatgccgg catcgtccgc caatatgccg cgctgctgtc tccggaatcc gtcaacctgg
    15121 ggcttcaggc atttatccgc gtttccatcc gcaaagcaaa agacgcgcgg gaagactttg
    15181 ccgcatcggt tcgaaaatgg cctgaagtct tgagctgctt cgccctgaca ggggaaaccg
    15241 actacctgct tcaggcgttt tttaccgata tgaacgcgtt ttcccatttt gttttggata
    15301 cgctcctgtc ccaccacggc gtacaagatg cgcaatcgag ctttgtttta aaagaaatca
    15361 aacacaccac ctccctgccg ctcaaccacc tgctgaagga atagtgccct tcccgatttt
    15421 cccgcacgtg caatctgcaa acacatttac atgacaataa tgaatatcaa tacttccgaa
    15481 aataaagatg ctgttgccga acacaccgga caatggttgg aaaaagccgt catcggtctg
    15541 aacctgtgtc cctttgccaa agccccccac gttaaaaacc ttgtccgcat cgcaatcagc
    15601 gaagccaaac accttgacag ttttttggaa gacttggacg aagaactgca gcgactgggc
    15661 aatacacccg ccaccgaact ggaaaccacc ctgctggttc acccgaccct attccccgat
    15721 ttcgacgtat tcaacgatat gctcgatatt gccgatgccg ccgttgtcga aaacggcttg
    15781 gaaggcatca tccaaatcgc cccgtttcat cccgatttcc aatttgaagg cacggattcg
    15841 gacgacatcg gcaactacac caaccgttct ccctatccga cactgcatct gatacgcgaa
    15901 gacagcattg ccaaagccgc acaagccttt cccgacgctt cggcaatatt cgaacgcaat
    15961 atcgccctgc tggaaaaaat gggacatgag ggctgggtaa aactcggtat cacatcctgc
    16021 ccttatccgc acaataagaa aaatatttca aaatgatacg ttatctttta attgcctgcg
    16081 gcggcatctc cctgctgttg gggataatcg gcattttttt gccgctgttg ccgaccacgc
    16141 cgttcgtact gctctccgcc gcctgctggg caaaggcatc cccgcgcttt caccgctggc
    16201 tgcaccgaca ccgctatttc ggtccgatgg ttcataactg ggaacaaaac ggcgcagtgc
    16261 cgcgcaaagc caaaatattc gccatcagta tgatgaccgc atcctgcctg ataatgtttt
    16321 ggcagtttcc ccaacgctgg tgggtcgggg cggtttcatc ggttttttgt tcccttgtcg
    16381 ccatatggat gtggcgcagg cccgaatctt gaatgccgta ctgaaaggga taagggcaaa
    16441 caaacggggg gcaaacctgt ttcattgcaa atatatgtta aaataaattc atttttcgtt
    16501 ttcgatagat tatttattaa agatatatat ttatttgttt taaataaaat tatttatcaa
    16561 aaagaacata tattcccaag cacagcaatc cgccttcccg ccgccttccg gtttgggaaa
    16621 ctggtttatc ctgattattt actttacaat caatcggaaa acttttttca aaaacaaaca
    16681 ggcagcacag tccgcctatg tccgggcggc acggtgcctg tatcactccc acgcgccgcg
    16741 caaggcagtg cttgaatcga ggaaacacga tgcgccacct acccctgttt tcactaatgc
    16801 ttttccccgc atcggtttac gccgcagatt tggacggcgc aaacctaaac ctgctgtgga
    16861 gcctgccctt tgccctgatt ttgctgtcta tcgcattggg tcccttgttt ttttcgcata
    16921 cctggcatca ccattacggc aaaattaccg ccttttggac attgctcttc ctcatcccgt
    16981 tcagtttggt ttttggcgcg tccgccggta tccataccgt cgcacacgca ctcgttgaag
    17041 aatacatccc tttcatcctg ctgctgcttg ccctgtacac catttcaggc ggcattttgg
    17101 tttggggcga cttgaacggc acacccaagc tcaacaccgc cctgcttgcc gtcggtacgg
    17161 cacttgcctc tatcatggga acgaccggcg cagcaatgct gatgattcgt ccgctgctga
    17221 aagccaacca aaaccgtacc cgccgcgtgc acatcgtcat cttcttcatt ttcctggttg
    17281 caaacatcgg cggcggtctg acccctttgg gcgacccccc actcttcctc ggcttcctca
    17341 aaggcgtaga tttcatgtgg acggtcaaac atatgttcgc ccccgtcctg atcagcaccg
    17401 ctgtcctgtt gaccgccttc tatttcatcg acaaccgttt cttcaaacag gaaagcattg
    17461 cacaagatac gccggcacaa caggaaaaac ccgaaaaaat cgccatcttc ggcaaatgga
    17521 acttcctcct gctttcgggc gtggtcggcg cggttctaat gtccggcctt tggaaacccg
    17581 aacacccggg atttgaaatc ctcggcagcc gttacgccct gcaaaacctc gtccgcgatg
    17641 tcatcctgat tgcattgacc gccgtatcta tggcaatcac gcccaaacaa gtccgcgcag
    17701 gcaacgaatt caactttgaa cccatcgccg aagtgggcaa actcttcctc ggcatcttca
    17761 tcaccatctt tcccgtcctg agcattctga aagcaggcga ggcaggcgcg ctgggcgggg
    17821 tggtatcgct ggttcacgat acggcaggtc atccgattaa tgtgatgtat ttttggatga
    17881 gcggcatatt gtcggcattc ttggataacg cgcccactta tctcgttttt ttcaatatgg
    17941 cgggcggcga tgcccaagcc ttgatgacgg gtaccctgtt tcattcgctg ctggcggttt
    18001 ctatgggttc ggtattcatg ggcgcactga cctacatcgg caacgcaccg aacttcatgg
    18061 tcaaggccat tgccgaacag cgcggcgtac cgatgccgac tttcttcggc tatatgatgt
    18121 ggtcggtcgc cttcctgaca cccgtcttca tcgtacatac ccttatcttt ttcgttttca
    18181 aactgctgta aacgctatgc cgtctgaaca ttcagacggc attttaaatt ccggcataat
    18241 caaatcaata tccccccttc cgacaattat agtggattaa caaaaatcag gacaaggcga
    18301 cgaagccgca gacagtacaa atagtacggc aaggcgaggc aacgccgtac tggtttaaat
    18361 ttaatccact gtaaaaacgg cttccgcaag gaaaaaagca gcaaatctga caaacaggta
    18421 caattcctga tagaatctaa cactttgcta cattaattta ttcaatgctt ttgatgccac
    18481 gcgacacggt atcaaaacac gccgttttta ccttaaccat cacaagtaat gcaaatatat
    18541 gattaaaatc aaaaaaggtc taaacctgcc catcgcgggc agaccggagc aagtcattta
    18601 tgacggcccg gccattaccg aagtcgcgtt gcttggcgaa gaatatgccg gtatgcgccc
    18661 ctcgatgaaa gtcaaggaag gcgatgccgt caaaaaaggc caagtgctgt ttgaagacaa
    18721 aaagaatccg ggcgtggtgt ttaccgcgcc ggcttcaggc aaaatcgccg ccatccatcg
    18781 cggcgaaaag cgcgtacttc agtcggtcgt gattgccgtt gaaggcaacg acgaaatcga
    18841 attcgaccgc tacgcgcccg atgccttggc aaaattgagc ggcaaagaag tgcgccgcaa
    18901 tctgattcaa tccggtttgt ggactgcgct gcgtacccgt ccgttcagca aaatccctgc
    18961 cgtcgatgcc gagccgttcg ccatcttcgt caatgcgatg gacaccaatc cgctggcggc
    19021 agaccctgtg gttgtgatca aagaagccgc cgaggatttc agacgaggtt tgctggtatt
    19081 gagccgtttg accgagcgta aaatccatgt gtgtaaagca gcaggcgcag acgtgccgtc
    19141 tgaaaacgcc gccaacatcg aaacacatga attcggcggc ccgcatccgg ccggtttgag
    19201 tggcacgcac attcatttca ttgagccggt cggtgcaaac aaaaccgttt ggaccatcaa
    19261 ttatcaagat gtaattgcca tcggacgttt gtttgcaaca ggccgtctga acaccgggcg
    19321 cgtggttgcc ttgggtggtt ctcaagtcaa caaaccacgc ctcttgcgta ccgttttggg
    19381 tgcgaaagta tcgcaaatta ctgcgggcga attggttgac gcagacaacc gcgtgatttc
    19441 cggttcggta ttgaacggcg cgattgcaca aggcgcgcac gattatttgg gacgctacca
    19501 caatcagatt tccgttatcg aagaaggccg cagcaaagag ctgctcggct gggttgcgcc
    19561 gcagccggac aaatactcca tcacgcgtac aaccctcggc catttcctga aaaacaaact
    19621 cttcaagttc aacacagccg tcaacggcgg cgaccgcgcc atggtgccga ttggtactta
    19681 cgagcgcgtg atgcccttgg atatcctgcc caccctgctt ttgcgcgatt taatcgtcgg
    19741 cgataccgac agcgcgcagg cattgggttg cttggaattg gacgaagaag acctcgcttt
    19801 gtgcagcttc gtctgcccgg gcaaatacga atacggcccg ctgttgcgca aagtgctgga
    19861 aaccattgag aaggaaggct gattatgggc ttgaaacatt ttctggaaaa aatcgaaccg
    19921 cacttcctgc cgggcggcaa acatgaaaaa tggtatgccc tctacgaagc ggcggcgacg
    19981 attttctaca catccggtgc ggtaacgcgc aaagcggcac acgtccgcga cgcgctcgac
    20041 tccaagcgca tgatgatttt ggtgtggctg gctttgttcc ccgccatgtt ttacggcatg
    20101 tacaacgtcg gcgcacaggc attcggtgcc ttaacgcccg atttgctgca acaaagcatc
    20161 gccaacgact ggcattacac ccttgccgac gctttgggca tcaatatgtc gtctgaagcg
    20221 ggcgtgttgg gcaaaatgct gttcggcgcg atttacttcc tgccgattta cgcgaccgta
    20281 tttgccgtcg gcggtttctg ggaagtcttg ttcgccaccg tacgcaaaca cgaaatcaac
    20341 gaaggtttct ttgttacctc gattctgttt gccttaatcg ttccgcccac gctgccgctg
    20401 tggcaggcgg ctttgggtat ttctttcggc gttgtggttg cgaaagaagt attcggcggt
    20461 acgggtaaaa actttatgaa ccctgcgctg gcaggccgcg ccttcctgtt cttcgcctac
    20521 cccgccaact tgagcggcga tgcggtttgg acggcggttg acggctattc cggcgcaacc
    20581 gcgctggcgc aatgggcggc acacggtgca gacggcctga aaaacgccgt aaccggtcaa
    20641 accatcactt ggatggacgc gtttatcggc aaactgcccg gctccatcgg cgaagtctcc
    20701 actttggcac tcttaatcgg cggcgcgttt atcgtgtttg cccgcatcgc ttcttggcgc
    20761 attattgccg gcgtgatgat cggtatgatt gcgatgtctt cgctgttcaa cttcatcggt
    20821 tcggacacca acgccatgtt tgctatgcct tggtactggc atttggtcgt cggcggcttc
    20881 gccatcggta tgctgtttat ggcgaccgac cccgtttccg cttcctttac caatgtcggc
    20941 aaatggtggt acggcgcgct gatcggcgta atgtgcgtat tgatccgcgt ggtcaatccg
    21001 gcttaccccg aaggcatgat gttggcgatt ctgtttgcca acctgtttgc cccgattttc
    21061 gactatttcg tcgcacaagc gaacatcaaa cgcagaaagg cgcgcagcaa tggctaagaa
    21121 attcgataaa gacagcttca gcggcacgct gattgtcgtg ttggcggtca gcctgatttg
    21181 ctcggtcatc gttgccggtg cggtcgtcgg cttgaaaccc atccaagaga aacaaaaact
    21241 ccaagacaaa caaggctata tcttgagcgt agccggtttg atggataagg acaccgacat
    21301 cggtaaaacc tttgccgagc gtatcgagca acgtgttgtc gatttggcga ccggcgaata
    21361 cgtcgccgat gcgcctaaag acttcagcgc gcgcatcgca ggcaaagacc ctgcccaaag
    21421 catccgcatc aaacccgaag acgatttggc aggcatcaaa agccgtgcca aatacaccga
    21481 ggtttatttg gtaaaaggcg aagacggcaa aatcgggcaa atcatcctgc ctatgcacgg
    21541 taacggtttg tggtcggtca tgtacggctt tgtcgccatc cagcccgacg gcaacaccat
    21601 caacggcatt acctactacg aacaaggcga aaccccgggc ttgggcggcg aaatcggcaa
    21661 tccgttgtgg cagcaaaaat tcgtcggcaa aaaactgttt gacggacaag gcaaactcgc
    21721 cctgcacgtc ggcaaaggcg cgggttcgga caaagaacac ggcgtagatg ccctctccgg
    21781 cgcatcgctg acatccaaag gcgtgcaagg ttcgttcgcc tactggttcg gcgaaaacgg
    21841 ctatatcccc tacctgaaca aattgaaatc agcaggagcg caataatggc tgatatgaaa
    21901 cgcttgaaac atttgatgtt ttcacccttt atcgacaaca acccgattgc cttgcaggtt
    21961 ttgggtattt gttcggcttt ggcggttacc accaaacttc agacggccat cgtgatgggt
    22021 atttccgtag ctttggtaac cggtttttcc agcttcttca tttcgctggt acgcaactac
    22081 atccccaaca gcatccgtat tatcgtgcaa atggcgatta tcgcgtcgct ggttacgctg
    22141 gtcgaccaac tcttgcaggc atttgcctac gaattgtcca aacagctttc cgtattcgtc
    22201 ggtctgatta ttaccaactg tatcgtgatg ggccgcgccg aagcatttgc gatgaaagag
    22261 ccgccgctgg aaagcctgat cgacggcatc ggcaacggcg cgggctacgg gatgatgctg
    22321 cttgtcgtcg ccaccgtccg cgaactgatt ggctcgggca aactcttggg ctacaccgtt
    22381 ttccaaaccg tgcaggacgg cggctggtat cagaccaacg gcttgttcct gctcgccccc
    22441 agcgcgttct tcatcatcgg ctttttgatt tggggactgc gtacctggaa acccgaacag
    22501 gcggaggaat aagctatgga acactatttg agcctcttca tcaaatccgt cttcattgaa
    22561 aatatggcac tatccttctt tttgggtatg tgcacgtttt tggcggtatc caaaaaagta
    22621 tccaccgcat tcggtttggg tgtggcggta attttcgtac tcgggctgtc cgtccctgtc
    22681 aaccaactcg tttactcgct gctcaaagac ggcgcgattg tcgaaggcgt ggatttgacc
    22741 tttttgaaat tcatcacctt catcggcgtg attgccgctt tggtgcagat tttggaaatg
    22801 ttcttggata aattcgtccc cgccctctat aacgcgttgg gcatctacct gccgctgatt
    22861 accgtgaact gcgcgatttt cggcgccgta tcgtttatgg cgcaacgcga atacaacttc
    22921 ggcgagtccg ttgtatacgg cttcggcgcg ggcttgggct ggatgttggc gattgtcgct
    22981 ttggcgggca ttaccgaaaa aatgaaatat tcggacgctc ccaaaggcct caaaggcttg
    23041 ggcattacct ttatcgccgc cggcctgatg gcgatggcgt ttatgtcgtt ctccggcatc
    23101 cagttataag aaagggaccg gtatggagat tattttaggt atcgtgatgt ttaccgtcat
    23161 cgttttggtt ttggcactga tgattctatt tgccaaatcc aaactggtca gcgaaggcga
    23221 catcaccatc aaagtcaacg gcgaaaaaga gctgacgatg cccgccggcg gcaaactctt
    23281 gggcgcgctt gccaacgaag gcatctttat cccctccgcc tgcggcgggg gcggttcgtg
    23341 cggacaatgc cgcgtcgtcg taaaaagcgg cggcggcgac atcctgccga ccgagctgtc
    23401 ccacatcagc aaacgcgaag cacgcgaagg ctgccgtctg tcgtgccaag tcagcgtcaa
    23461 aaccgacatg gacatcgaag tgcccgaaga agtgttcggc gtgaaaaaat gggaatgcac
    23521 cgtcatctcc aacgataaca aagccacgtt cattaaagaa ctcaagcttg ccattcccga
    23581 aggcgaagaa gtccccttcc gcgccggcgg ctacattcaa attgaagctc ctcctcacac
    23641 tgttgcctac aaagacttcg acattcctaa ggaatatcac gaagactggg acaaatacaa
    23701 tttgtggcaa tacgtttcca aagtggacga gccgattttg cgcgcctact ctatggcttc
    23761 ataccctgaa gaaaaaggca tcattatgct gaacgtgcgt atcgccacgc cgcccccacg
    23821 cgtacctgat gcgcctccgg gacaaatgtc gtcctacatc tggtcgctca aacccggtga
    23881 taaagtaacg atttccggtc cgtttggcga attctttgcc aaagataccg atgccgaaat
    23941 ggtatttatc ggcggcggcg cgggtatggc tccgatgcgt tcccacattt tcgaccagct
    24001 gaaacgtttg aactccaaac gcaaaattac cttctggtat ggtgcacgtt ccaaacgcga
    24061 gatgttctat gtcgaagact tcgaccaact cgcggcagaa ttcccgaact tcacgtggca
    24121 cgtcgccctg tccgatccgc tgcctgaaga caactgggac ggttacacag gcttcattca
    24181 caacgtggtt tacgaaaacc acctgaaaaa tcacgaagcg ccggaagact gcgaatttta
    24241 tatgtgcggg cctccgatta tgaaccagtc cgtcatcaaa atgctcaaag acttgggtgt
    24301 ggaagacgaa aacatcctct tggacgattt cggcggctaa cagacaaaaa ggaagaaact
    24361 tcggtttctt ccttttttta tccgataccg tccgaacacc cttcagacgg catccgccca
    24421 taccagtatc aatatcgttg aacttccatt tttaccctgc ggcggatgtg cggttaaata
    24481 ttctggcgga aaagcaaaga agtatacttc tttttagtta tggttgattc cataactaaa
    24541 aaagtatcga taaacccatt ttgcgaggta cggataatgt ctgacagctt tgaaaacagc
    24601 cccgaatacg atgattggat tgaatcgggc ggtcgtgatg aagattacga atactactac
    24661 aataaatggc aacgcaggac gcgctgacca ttaaaccttg acaaaccggt tggtaaaaca
    24721 ccggtttgtt ttttatagtg gattaaattt aaaccagtac ggcgttgcct cgccttgccg
    24781 tactatttgt actgtctgcg gcttcgtcgc cttgtcctga tttaaattta atccactata
    24841 ttaccgccac ctaaacgacg ggcgatgccg tccgaacacc cttcagacgg catcggcata
    24901 gaaacatacc ggccgttttg cgatataatt caaaccattt gccaaaaccg tcaaacacta
    24961 tgccgtctga aacacgcctg ccgaacttta tccgcacctt gatatttgcc ctgagtttta
    25021 tcttcctgaa cgcctgttcg gaacaaaccg cgcaaaccgt taccctgcaa ggtgaaacga
    25081 tgggcacgac ctataccgtc aaataccttt caaacaatcg ggacaaactc ccctcccctg
    25141 ccgaaataca aaagcgcatc gatgacgcgc ttaaagaagt caaccggcag atgtccacct
    25201 atcagcccga ctccgaaatc agccggttca accaacacac agccggcaag cccctccgca
    25261 tttcaagcga cttcgcatac gttactgccg aagccgtccg cctaaaccgc ctgacacacg
    25321 gcgcgctgga cgtaaccgtc ggccctttgg tcaacctttg gggattcggc cccgacaaat
    25381 ccgttacccg tgaaccgtcg ccggaacaaa tcaaacaagc agcatcttat acgggcatag
    25441 acaaaatcat tttgaaacaa ggcaaagatt acgcttcctt gagcaaaacc caccccaagg
    25501 cctatttgga tttatcttcg attgccaaag gcttcggcgt tgataaagtt gcgggcgaac
    25561 tggaaaaata cggcattcaa aattatctgg tcgaaatcgg cggcgagttg cacggcaaag
    25621 gcaaaaacgc gcgcggcgaa ccgtggcgca tcggtatcga gcaacccaat atcatccaag
    25681 gcggcaatac gcagattatc gtcccgctga acaaccgttc gcttgccact tccggcgatt
    25741 accgtatttt ccacgtcgat aaaagcggca aacgcctctc ccatatcatt aatccgaaca
    25801 acaaacgacc catcagccac aacctcgcct ccatcagcgt ggtcgcagac agtgcgatga
    25861 cggcggacgg cttgtccaca ggattattcg tattgggcga aaccgaagcc ttaaagctgg
    25921 cagagcgcga aaaactcgct gttttcctga ttgtcaggga tacaggcggc taccgcaccg
    25981 ccatgtcttc cgaatttgaa aaactgctcc gctaaacata caaaccgatt aggaaacacc
    26041 atgaaaaccc tgctcctcac cttcggcatc ttcctgaccg tcatcatcgg tatggcggtc
    26101 ggctatatct tctccaaacg caccatcaaa ggcagttgcg gcggcattac cgccttgggt
    26161 atgaaaaaaa tgtgcgactg cgacacgcct tgcgacaccc tgcaaaagaa actggatgaa
    26221 gaaaaacagg caggcggcat acgggttgac cgttaacacc gaaacaaaat gccgtctgaa
    26281 gcccgacagg cgggttcaga cggcattgcc gctttacttc gatcggttta tacgcaaaac
    26341 gcgcttcagg aaataaatca gattattccc cagacgcctt caggcttcct tctgtgccac
    26401 cgtaaccata gccgggcgca acacgcggtc ggacagcgta taacccttct tcatcacgcc
    26461 caccacggta ttgggttcct gttcgcttgc caccgcctgc atcgcctgat ggatattcgg
    26521 atcgagctta tcgcccgctt taggattgat ttccttgatt tgcgtagcat caaatgcttt
    26581 ctgcaactcg ttcaaagtca tctgcacgcc cattttcagc gcatcgaaat tgccgctctg
    26641 atccaaaagc gccatttcca gataatcctt gaccggcagc atttccacgg caaacttctg
    26701 tccggcgaac ttgtgcgtat ccgcaatttc ctgctggtgg cggcggcgca ggttttgctc
    26761 gtttgccaaa gcgcgcagct gctcgtcttt caactgcgct tccagctcgg caatccgcgc
    26821 ctgcaaatcc tcataagccg gctctgcggc agcctgttcc tgcacaccgt ccgcatttcc
    26881 tactgtctcg acggtttcca ccgcctccac attttcaacc gcttcttcac tgttttgctg
    26941 ctgtgtctgt tcgctcatat cgtatccctt aaaacaaatt ggaaatcaaa atccagttat
    27001 tacccgcgca agataaggac attttcaaga aacttcaagc aaaagcagag aatttcaaat
    27061 tcattttcaa atcccctacc gaaaaaataa tatagacggt aagatactgc cgaccatatc
    27121 gattttcaaa cgtcatcact catgaaaaaa gaccatttaa acacaaccgg tttcgacctc
    27181 tggcacacca tccgcgaaga aaccgcggcc gcggtctccg ccgaaccgat gctggcaagt
    27241 tttttgcacc aaaccgtgtt gcgccacgag tccctcggct ccgtccttgc ctaccacctt
    27301 tccagcaaac tcggcagccc gattatggac gtgcgcgcgc tgtttgaaat ctaccagcag
    27361 gcgttgggca gcgacaccca aatcggcaaa tgcgtcgaag cagacttaaa agccatctac
    27421 gaacgcgatc ccgcctgcga cgaatattcg ctgccgcttt tatatttcaa aggcttccac
    27481 gcgattcagg cacaccgcat caaccatcgg ctgtatctcg acgggcgcaa aacgctggcg
    27541 tatttcctgc aaaaccgtat gtccgaagta ttcggcgtgg acatccatcc cgccgcccgt
    27601 ttcggatacg ggctgatgct cgaccacgcc accggctttg ttgccggcga aaccgccgtg
    27661 ttgggcaaca atatttcgat tttgcacggc gtaacgctcg gcggttcggg caaagaaggc
    27721 ggcgaccgcc accctaaaat cggcgacggc gtgatgatcg gcgcaaacgc ctcgatattg
    27781 ggcaatatcc gcatcggcag caatgccaaa atcggggcgg gcagcgtcgt ggtttcagac
    27841 gtgccgccgt ccatcacggt tgtcggcgta cccgccaaac ccgtggcgcg atcgctcaaa
    27901 acaccgtcgg cggatatgga tcaaaatatc cagtttgccg aaatcgactt tatgatttga
    27961 atatccgcac caatgccgtc tgaaacgcca aacgtgcttc agacggcatt gcccgcttca
    28021 agcctgcgcc ttgatatgcc gccgataccg gcacttgcca gtcggacaaa atgcctttta
    28081 ttcgatacac ccgattccca cgcaaccgga aatatagt
//
LOCUS       DAXIDM010000013        26853 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000013 DAXIDM010000000
VERSION     DAXIDM010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 26853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26853
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.013"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            246..311
                     /locus_tag="ACFOAE_000475"
                     /pseudo
     CDS             246..311
                     /locus_tag="ACFOAE_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003796056.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family metal-binding protein"
     gene            415..798
                     /locus_tag="ACFOAE_000476"
     CDS             415..798
                     /locus_tag="ACFOAE_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HFC6884030.1"
                     /translation="MYCLRLRRLVLIFVNPLYIIATTVPAQQTFLDAAELMQWSRETE
                     WLGLNVIAHRNFGKQHAQVEFEACFRDGQHRSAHHELSGFVNIGGQWYFIDPTVPHPA
                     MKQPCICGSGKKFKACCGKYLQPVA"
     gene            complement(1089..1883)
                     /locus_tag="ACFOAE_000477"
     CDS             complement(1089..1883)
                     /locus_tag="ACFOAE_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFC6884031.1"
                     /translation="MLHRLQKVVRHIAQTEIMPRFLNTPSHRKEDGSMLSEADIAAQT
                     AFAAALPLLIDCPMLGEEMSRQEQSALWAEYSGEKGLWIVDPIDGTNNFVNGLPHFAV
                     SVAFVRNGRAELGVIYNPVSGECFYAERGQGAFLNGTRLPLRLVDKKLNEAIAGVEIK
                     YLRSGKLSSRMSTLAPFGTVRSMGSSTLDWCYLACGRYDVYVHGGQKLWDYAAGALIF
                     EEAGGRLTTLEGDGFWSGEHVFKRSVVAALEPKLFERWVGWIRENQ"
     gene            2092..2817
                     /locus_tag="ACFOAE_000478"
     CDS             2092..2817
                     /locus_tag="ACFOAE_000478"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFC6884032.1"
                     /translation="MPRFHLPENLSVGQTVALPDNIVRHLNVLRVRPNENITLFDGKG
                     KAHAARLTVLEKRRAEAEILHEDTTDNESPLNITLIQSISSGDRMDFTLQKSVELGVT
                     AIQPVISERCIVRLDGERAAKRLARWQEIVISACEQSGRNTVPPVLPIIGYREALDKM
                     PSESTKLIMSINRARKLGDIRHPSGAIVFMVGPEGGWTEQEEQQAFEAGFQAVTLGKR
                     ILRTETAPLAALAAMQTLWGDFA"
     gene            complement(3436..4242)
                     /locus_tag="ACFOAE_000479"
     CDS             complement(3436..4242)
                     /locus_tag="ACFOAE_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="HFC6884033.1"
                     /translation="MQNHVISLASAAERRAHIADTFGRHDIPFQFFDALMPSEALEQA
                     MAELVPGLSAHPYLSGVEKACFMSHAVLWKQALDEGLPYIAVFEDDVLLGEGAEKFLA
                     EDAWLQERFDPDSAFIVRLETMFMHVLTSPSGVADYCGRAFPLLESEHWGTAGYIISR
                     KAMRFFLDRFAVLPSERLKAVDWMLFSSFLDKGGMTVCQLTPALCIQSETLPSQLKNG
                     RQESYRNRRSPKVLLKRALGKIGREIERARERKRQKKLEKHLGRHVVPFE"
     gene            complement(4284..4379)
                     /locus_tag="ACFOAE_000480"
                     /pseudo
     CDS             complement(4284..4379)
                     /locus_tag="ACFOAE_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
     gene            complement(4391..5218)
                     /locus_tag="ACFOAE_000481"
     CDS             complement(4391..5218)
                     /locus_tag="ACFOAE_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="HFC6884034.1"
                     /translation="MQNHVISLASAAERRAHIAATFGARGIPFQFFDALMPSERLEQA
                     MAELVPGLSAHPYLSGVEKACFMSHAVLWKQALDEGLPYIAVFEDDVLLGEGAEKFLA
                     EDAWLQERFDPDSAFIVRLETMFMHVLTSPSGVADYCGRAFPLLESEHWGTAGYIISR
                     KAMRFFLDRFAALPPEGLHPVDLMMFSDFFDREGVPVCQLNPALCAQELHYAKFHDQN
                     SALGSLIEHDRLLNRKQQRRDSPANTFKRRLIRALTKISREREKRRQRREQFIVPFQ"
     gene            complement(5260..6306)
                     /locus_tag="ACFOAE_000482"
     CDS             complement(5260..6306)
                     /locus_tag="ACFOAE_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC6884035.1"
                     /translation="MPSEAFRRHRAYRENKLQPLVSVLICAYNVEKYFAQSLAAVVNQ
                     TWRNLDILIVDDGSTDGTLAIARRFQEQDGRIRILAQPRNSGLIPSLNIGLDELAKSG
                     GGGYIARTDADDIAAPDWIEKIVGEMEKDRSIIAMGAWLEVLSEEKDGNRLARHHEHG
                     KIWKKPTRHEDIATVFPFGNPIHNNTMIMRRSVIDGGLRYNTERDWAEDYQFWYDVSK
                     LGRLAYYPEALVKYRLHANQVSSKHSVRQHEIAQGIQKTARNDFLQSMGFKTRFDSLE
                     YRQIKAVAYELLEKHLPEEDFERARRFLYQCFKRTDTPPAGVWLDFAADGRMRRLFTL
                     RQYFGILHRLLKNR"
     gene            complement(6323..8386)
                     /gene="glyS"
                     /locus_tag="ACFOAE_000483"
     CDS             complement(6323..8386)
                     /gene="glyS"
                     /locus_tag="ACFOAE_000483"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFC6884036.1"
                     /translation="MMTQTLLIELLTEELPPKALNNLGNHFAASVAEGLEKAQLIAGA
                     AEFTAYASPRRLAVQVKNVKAVQADQKIVKKGPAVANAVKDGAPTKALEGFARGAGAK
                     IEDLTIVHDGKQDVYAYEYVQTGKPLGELLEDIINAAVKKLPIPKVMRWGSSTFTFVR
                     PVHGLIVLHGGDIVNVSVLGLQSSNQTLGHRFLSNGEITIENADSYAEQMRGQGKVVA
                     SFAERKAAIQTALEGQARRLNATVAADEALLDEVTALVEWPVVLEAGFEEHFLAVPQE
                     CLILTMQQNQKYFPLLDQNGKLMNRFLLVSNLQTEDPSHIIQGNERVLRARLSDAEFF
                     YKQDQKATLESRLPKLANVVYHNKIGSQAERIERLQSIAAHIAKALDADAAAAERAAR
                     LAKADLVTEMVGEFPELQGTMGKYYARLDGETEEIAEAVEQHYQPRFAGDKLPESKIA
                     AAVALADKLETLVGIWGIGLIPTGDKDPYALRRAALGILRMLMQYGLDVNELIQTTFD
                     SFPKGLLNEKTPSETADFMQARLAVLLQNDYPQDIVAAVLAKQPRRLDDLTAKLQAVA
                     AFKQLPEAAALAAANKRVQNLLKKADAELGAVNESLLQQDEEKALFAAAQGLQPKIAA
                     AVAEGNFQTALSELASVKPQVDAFFDGVMVMAEDAAVKQNRLNLLNRLAEQMNAVADI
                     ALLGE"
     gene            complement(8407..8817)
                     /locus_tag="ACFOAE_000484"
     CDS             complement(8407..8817)
                     /locus_tag="ACFOAE_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding protein YggL"
                     /protein_id="HFC6884037.1"
                     /translation="MPVYFRTPSRKRLHKMNRRQHKKLHLGEFQTLIFGVQGSLHQAE
                     DDAEAFGRFMDELIAYLVVNGLEMAGGGDCGDFSCLFQKSGARGLGETEKKAIISWLA
                     DREDVATLYATPLVDGFYGDDGWENYSETYKQAD"
     gene            complement(8894..9799)
                     /gene="glyQ"
                     /locus_tag="ACFOAE_000485"
     CDS             complement(8894..9799)
                     /gene="glyQ"
                     /locus_tag="ACFOAE_000485"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFC6884038.1"
                     /translation="MLTFQQIIFKLQTFWADKGCTVIQPFDMEVGAGTSHPATCLRAL
                     GPEPWFAAYVQPSRRPKDGRYGDNPNRLQHYYQFQVALKPAPANIQDLYLDSLRELGI
                     DPKVHDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGIDCTPVLGEITY
                     GIERLAMYLQGVENVYDLVWAKTLDGNTVTYGDVYHQNEVEQSTYNFEYSDADWLLRQ
                     FNDYEAQAKRLLAEENAALALPAYELVLKAGHTFNLLDARGAISVTERATYIGRIRAL
                     SRAVAQKYVESREKLGFPLMKANAA"
     gene            complement(10117..10539)
                     /locus_tag="ACFOAE_000486"
     CDS             complement(10117..10539)
                     /locus_tag="ACFOAE_000486"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFC6884039.1"
                     /translation="MSIMEVEVVSSEQKIYSGEATFIVVPTVQGELGIYPRHEPIMSL
                     VRPGALRLTVPGEDKEVLVAVSGGVLEVQPDKVTVLADVAVRSAEMDQARAEEAKKAA
                     EAGISQAKDDKALAEAHKALAAAIAQLKTLDYIRSHKK"
     gene            complement(10550..11947)
                     /gene="atpD"
                     /locus_tag="ACFOAE_000487"
     CDS             complement(10550..11947)
                     /gene="atpD"
                     /locus_tag="ACFOAE_000487"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFC6884040.1"
                     /translation="MSQGKIVQIIGAVVDVEFPRDMIPRVYDALKLDENGLTLEVQQL
                     LGDGVVRTIAMGSSDGLKRGMTVSNTGAPITVPVGKGTLGRIVDVLGTPVDEAGPIDT
                     DKSRAIHQAAPKFDELSSTTELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMME
                     LINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRV
                     ALTGLTMAEYFRDEKDENGKGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTL
                     AEEMGRLQERITSTQTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLG
                     IYPAVDPLDSTSRQLDPMVLGQEHYDVARGVQSTLQKYKELRDIIAILGMDELSDEDK
                     LTVMRARKIQRFLSQPFHVAEVFTGSPGKYVALRDTIAGFKAILNGEYDHLPEQAFYM
                     VGSIEEAVEKAKTLN"
     gene            complement(11985..12860)
                     /gene="atpG"
                     /locus_tag="ACFOAE_000488"
     CDS             complement(11985..12860)
                     /gene="atpG"
                     /locus_tag="ACFOAE_000488"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFC6884041.1"
                     /translation="MAVGKEILTKIRSVQNTQKITKAMQMVSTSKMRKTQERMRLARP
                     YAEKVRMVMSHLAQTNTDHGIPLLESHREIRRVGFILITSDKGLCGGLNANVLKKFLA
                     QVQEYRNQGIEEEIVCLGSKGLMACQSIGLNVVASAVNLGDTPKMEMLLGPLTELFQR
                     YEKHEIDRIHLVYSGFVNTMRQEPRMEVLLPIGENVIGDSAPKSPFSWEYRYEPTALA
                     VLEYLVRRYLESVVYQALSDNMASEQAARMVAMKAATDNAGNAIKELRLVYNKSRQAA
                     ITTELSEIVAGAAAV"
     gene            complement(12885..14432)
                     /gene="atpA"
                     /locus_tag="ACFOAE_000489"
     CDS             complement(12885..14432)
                     /gene="atpA"
                     /locus_tag="ACFOAE_000489"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFC6884042.1"
                     /translation="MQLNPAEISDLIKAKIENLSVNAEVRTRGTVISVTDGIVRIHGL
                     SDAMQGEMLEFPGNTFGLAMNLERDSVGAVVLGEYEHIKEGDTVTCTGRILEVPVGRE
                     LVGRVVDALGRPIDGKGPINTTLTAPIEKIAPGVIARKSVDQPMQTGLKAIDSMVPVG
                     RGQRELIIGDRQTGKTAVALDAIVNQKGTGVICIYVAIGQKASSIANVVRKLEEHGAM
                     EHTIVVAATASEAAALQYIAPYSGCTMGEFFRDRGEDALIVYDDLSKQAVAYRQISLL
                     LRRPPGREAYPGDVFYLHSRLLERAARVNEHEVEKLTNGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVIKKLGGG
                     IRLALAQYRELAAFSQFASDLDEATRKQLEHGEVVTELMKQKQFSTLNTAEMALTLWA
                     INNGSYSDVPVAKALAFESEFLSFVRTQHPEVLEAVNASGAMSDESEKTLEAAMKSFK
                     SSYAYQA"
     gene            complement(14443..14976)
                     /locus_tag="ACFOAE_000490"
     CDS             complement(14443..14976)
                     /locus_tag="ACFOAE_000490"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFC6884043.1"
                     /translation="MAEFATIARPYAKALFGLAQEKNQIESWLGGLEKLAAVVQEGKV
                     ASLIDRPETNASEKADILIDLVGLKDKELKNFVIVLAGQKRLSILPEVYAQYQDLTLS
                     FNHIKSAIIYSAYPLTDKQVGELAQMLNKRFDSELKISVEIEPELIGGIKVEVGDQVL
                     DLSVQGKLSALYTTMTN"
     gene            complement(14981..15451)
                     /locus_tag="ACFOAE_000491"
     CDS             complement(14981..15451)
                     /locus_tag="ACFOAE_000491"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFC6884044.1"
                     /translation="MNINATLFAQIIVFFGLVWFTMKFVWPPIAKALDERAAKVAEGL
                     AAAERGKSDFEQAEKKVAELLAEGRNQVSEMVANAEKRAAKIVEEAKEQASSEAARIA
                     AQAKADVEQELFRARESLREQVAVLAVKGAESILRSEVDASKHAKLLDTLKQEL"
     gene            complement(15522..15758)
                     /gene="atpE"
                     /locus_tag="ACFOAE_000492"
     CDS             complement(15522..15758)
                     /gene="atpE"
                     /locus_tag="ACFOAE_000492"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HFC6884045.1"
                     /translation="MGLIAIACGLIVALGALGASIGIAMVGSKYLESSARQPELIGPL
                     QTKLFLIAGLIDAAFLIGVAIALLFAFVNPFAGA"
     gene            complement(15815..16681)
                     /gene="atpB"
                     /locus_tag="ACFOAE_000493"
     CDS             complement(15815..16681)
                     /gene="atpB"
                     /locus_tag="ACFOAE_000493"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004464456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFC6884046.1"
                     /translation="MAGETITAADYIKHHLQSLTSLSDVTQGQGLKNIADFSFINLDA
                     VFFAVLLGVIGSFLLWRGAKKATAGVPGRFQAAVEILFEFVDDMCKSIIHNEKSRKAV
                     APLGLTLFVWIFLMNAMDMLPVDLLPMVWQGITGNHHALLRVVPTADLNTTLALAVGV
                     LLICIYYNIKIKGLGGWFHELFSAPFGAKLAPANFLLNLVEFLSKTVSHGMRLFGNMY
                     AGELVFLLIALLGGAWAASGSVEVMDPILFVFHIIAGLAWAIFHILVITLQAFIFMAL
                     AFVYIGQAHDAH"
     gene            complement(16671..17024)
                     /locus_tag="ACFOAE_000494"
     CDS             complement(16671..17024)
                     /locus_tag="ACFOAE_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HFC6884047.1"
                     /translation="MKQIIILQSAVLSICAAVAFAVWGFAGFLSAVGGGLSYLLPTFV
                     AVLLLKLFRGNPFLQSRMFVFGEILKVVLSLLSMLAVFAIWHQSLVFAPFLMGLLGVS
                     HLVFLVLLRVKDYGR"
     gene            complement(17392..17730)
                     /locus_tag="ACFOAE_000495"
                     /pseudo
     CDS             complement(17392..17730)
                     /locus_tag="ACFOAE_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229959.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17865..18725)
                     /locus_tag="ACFOAE_000496"
     CDS             complement(17865..18725)
                     /locus_tag="ACFOAE_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFC6884048.1"
                     /translation="MAKVKGGLGRGLDSLLANGADNSSGDRLTTVAVKDIRPGRYQAR
                     VQIDDEALQELADSIKAQGVIQPVIVREHGLSRYELIAGERRWRAAQIAGLTEIPAVI
                     KTISDETALAMGLIENLQRENLNPIEEAQGLKRLADEFGLTHETIAQAVGKSRSAISN
                     SLRLLSLPEPVQEMLYQRRLEMGHARALLTLPVVEQLELAQKAVKNGWSVREVERRSQ
                     AALQNKRPEPKKTAAADIGRLNDLLTEKLGVNAEIKTANHKKGRIILHFDTPETFDHI
                     LKQLGIDYRP"
     gene            18883..19452
                     /locus_tag="ACFOAE_000497"
     CDS             18883..19452
                     /locus_tag="ACFOAE_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFC6884049.1"
                     /translation="MVRRLIIGISGASGFQYGVKALELLRAQDIETHLVVSKGAEMAR
                     ASETAYARDEVYALADFVHPIGNIGACIASGTFKTDGMLVAPCSMRTLASVAHGFGDN
                     LLTRAADVVLKERRRLVLMVRETPLNLAHLDNMKRVTEMGGVVFPPVPAMYRKPQTAD
                     DIVAHSVAHALSLFGIDTPDSAEWQGMAD"
     gene            complement(19514..20377)
                     /locus_tag="ACFOAE_000498"
     CDS             complement(19514..20377)
                     /locus_tag="ACFOAE_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFC6884050.1"
                     /translation="MKTFFKTLSAAALALILAACGGQKDSAPAASASAAADNGAAKKE
                     IVFGTTVGDFGDMVKEQIQPELEKKGYTVKLVEFTDYVRPNLALAEGELDINVFQHKP
                     YLDDFKKEHNLDITEVFQVPTAPLGLYPGKLKSLEEVKDGSTVSAPNDPSNFARVLVM
                     LDELGWIKLKDGINPLTASKADIAENLKNIKIVELEAAQLPRSRADVDFAVVNGNYAI
                     SSGMKLTEALFQEPSFAYVNWSAVKTADKDSQWLKDVTEAYNSDAFKAYAHKRFEGYK
                     SPAAWNEGAAK"
     gene            complement(20536..21222)
                     /locus_tag="ACFOAE_000499"
     CDS             complement(20536..21222)
                     /locus_tag="ACFOAE_000499"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFC6884051.1"
                     /translation="MADLTFQQAVSNIIGMKGEIVRALGETFVMVGLSTTFAVVFGTL
                     LGVLLFVTSSRQLHYNKAVNFLLDNLVNLMRAFPFVILMIAMIPATRAIVGSTIGPVA
                     ASLVLSVSGLFYFARLVEQNLREVPKGVIEAAAAMGAPPVAIIRKVLLNEARAGMVSS
                     ITVLAIGLLSYSAAAGMIGGGGLGDLAIRYGYYRYQTEVIVFIVALLVLLVILIQSTG
                     NTLARKLDKR"
     gene            complement(21224..21961)
                     /locus_tag="ACFOAE_000500"
     CDS             complement(21224..21961)
                     /locus_tag="ACFOAE_000500"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFC6884052.1"
                     /translation="MIILDKVSKHYQTRDKTRFAAVEPTSLEIRDGEIFGLMGYSGAG
                     KSTLLRLINLLERPDSGKVNVCGQELTALDAAALRQARQNIGMVFQQFNLLNNRTVAG
                     NVAFPLEIAGWPSEKIKTRVAECLEIVGLTERAGHYPAQLSGGQKQRVGIARALAPKP
                     QVILADEPTSALDPATTRSVLECLEDINKRFNVTIVIVTHEMSVIRRLCDRAALLDKG
                     KVVEIVEVRGNQIHARSDIGRELIRED"
     gene            22492..24339
                     /gene="ltgA"
                     /locus_tag="ACFOAE_000501"
     CDS             22492..24339
                     /gene="ltgA"
                     /locus_tag="ACFOAE_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase LtgA"
                     /protein_id="HFC6884053.1"
                     /translation="MYLPSMKHSLPLLAALVLAACSSTHAPSSKTLADNIETAGLSAS
                     VPTRPAEPEGKTLADYSSYPSALDAVKQKNDAAVAAYLENAGDSAMAENVRNEWLKSL
                     GARKQWTLFAQEYAKLEPAGRAQEVECYADSSRNGYTRAAELVKNTGKLPSGCTKLLE
                     QAAASGLLDGNNAWRRVRGLLAGRQTTDARNLAAALGSPFDGGTQGSREYALLNIIGK
                     EARKSPNAAALLSEMESGLSLEQRSFAWGVLGHYQSQSLNVPAALDYYGKVADRRQLT
                     DDQIEWYARAALRARRWDELASVISHMPEKLQKSPTWLYWLARSRAATGNTQEAEKLY
                     KQAAATGRNFYAVLAGEELGRKIDTRNNVPDADANSVLRMAEDGAIKRALVLFRNSRT
                     AGDAKMRRQAQEEWRFATRGFDEDKLLTAAQTAFDHGFYDMAVNSAERTDRKLNYTLR
                     YISPFKDTVIRHAQNVNVDPAWVYGLIRQESRFVMGAQSRVGAQGLMQVMPATAREIA
                     GKIGMDAAQLYTADGNIRMGTWYMADTKRRLQNNEVLATAGYNAGPGRARRWQADTPL
                     EGAVYAETIPFSETRDYVKKVMTNAAYYASLFGAPHIPLKQRMGIVPAR"
     gene            24628..24840
                     /gene="rpsU"
                     /locus_tag="ACFOAE_000502"
     CDS             24628..24840
                     /gene="rpsU"
                     /locus_tag="ACFOAE_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011484193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFC6884054.1"
                     /translation="MPAIRVKENEPFEVAMRRFKRAVEKTGLLTELRAREAYEKPTTE
                     RKRKKAAAVKRLQKRLRSQQLPPKMY"
     gene            24972..25418
                     /locus_tag="ACFOAE_000503"
     CDS             24972..25418
                     /locus_tag="ACFOAE_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFC6884055.1"
                     /translation="MSLKIRLTEDMKTAMRAKDQVSLGTIRLINAAVKQFEVDERTEA
                     DDAKITAILTKMVKQRKDSAKIYTEAGRQDLADKENAEIEVLHRYLPQMLSAGEIRTA
                     VEAAVAETGAAGMADMGKVMGVLKTRLAGKADMGEVNKILKAVLTA"
     gene            complement(25496..25738)
                     /locus_tag="ACFOAE_000504"
     CDS             complement(25496..25738)
                     /locus_tag="ACFOAE_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884056.1"
                     /translation="MPSERNRVSDGILSDGAQTESVYRQNPFRCIETVLPLPIRYWDV
                     IASALECNYGAANQAIERQRQRAAAVAVHERVAKFL"
     gene            complement(25743..26135)
                     /locus_tag="ACFOAE_000505"
     CDS             complement(25743..26135)
                     /locus_tag="ACFOAE_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HFC6884057.1"
                     /translation="MPTSTKPYILRALCEWCSDNSLTPHILVWVNEHTRVPMQYVRDN
                     EIMLNIGATATQNLQIDNDWISFSARFGGQAHDIWIPVGHVLSLFARETGEGMGFELE
                     AYRPDTPPENTSAETAPRPAKKGLKLVK"
     gene            complement(26207..26812)
                     /locus_tag="ACFOAE_000506"
     CDS             complement(26207..26812)
                     /locus_tag="ACFOAE_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase N-terminal
                     domain-containing protein"
                     /protein_id="HFC6884058.1"
                     /translation="MMTLYSGITCPFSHRCRFVLYEKGMDFEIKDVDIYNKPEDLAVM
                     NPYNQVPVLVERDLVLHESNIINEYIDERFPHPQLMPGDPVMRGRGRLVLYRMEKELF
                     NHVQVLENPAATNKEQAKAREAIGNGLTMLAPSFSKSKYILGEDFSMIDVALAPLLWR
                     LDHYDVKLGKSAAPLLKYAERIFQREAFIEALTPAEKAMRK"
BASE COUNT         6320 a         7186 c         7034 g         6313 t
ORIGIN      
        1 ctgaaggcga tgtgtttgaa cctgttgaaa gcggccaaca ggttaagtgc gtccgctgcc
       61 gcctaaaaag cagcccggat gcctgattat cgggtatccg gggaggatta agggggtatt
      121 tgggtaaaat taggagatat ttggggcgaa aacagccgaa aacctgtgtt tgggtttcgg
      181 ctgtcgggag ggaaaggaat tttgcaaagg tctcaagcta tgccggctgc tgccgcccac
      241 ttcatctgcg ccaaatcctg ccgcccaccg ccgaagccct catgcgttcg cggtacagcg
      301 cgtatgtgct actatagtgg attaacaaaa accagtacag cgttgcctcg ccttagctca
      361 aagagaacga ttctctaagg tgctgaagca ccgagtgaat cggttccgta ctatttgtac
      421 tgtcttcggc ttcgtcgcct tgtcctgatt tttgttaatc cactatacat catcgctact
      481 accgttccgg cacaacaaac attcctcgat gccgccgaac tgatgcagtg gagcagagaa
      541 accgaatggc tgggcttgaa tgtcatcgca caccgcaact tcggcaaaca gcacgcccaa
      601 gtcgaatttg aagcctgctt ccgagacgga caacaccgat ctgcgcatca cgaactgtcc
      661 ggcttcgtca acatcggcgg acaatggtat tttatcgatc ctaccgttcc gcatcctgcg
      721 atgaaacaac cctgcatttg cggatcgggc aaaaaattca aagcctgctg cggcaaatat
      781 ctgcaacctg tcgcataaaa atgccgtctg aacgttcaga cggcattttt aacgcgcaaa
      841 aaaaaccatt cataccaagg gtaagtatga atggtcaata cattgcggga aaacgtctta
      901 cttgctgcac tgccgaaaag ggagaaacgg cagcggtaat cagcggaaag gattgtgccc
      961 gtataaatgt taagtaacgt taattatgaa aatataaccg atgtttcggc acacaatccg
     1021 caactgtccg gcgcaggcgg cggcaaagcc tgtttattca aacccttatt cctgcccatc
     1081 tgtccacctt actggttttc ccgtatccac ccgacccagc gttcaaacag cttcggttcg
     1141 agcgcggcaa cgaccgagcg tttgaacacg tgttcaccac tccaaaaccc gtcgccttcc
     1201 aaagtcgtca gcctgccgcc cgcctcctcg aaaatcaacg cacccgcagc atagtcccac
     1261 agcttctgcc cgccgtggac ataaacatca taacgcccgc acgccagata acaccagtcc
     1321 agcgtgctgc tgcccatact ccgcaccgta ccgaaaggtg cgagcgtact catgcggctg
     1381 gaaagtttgc ccgaacgcag atatttgatt tccacgcccg cgattgcctc attgagtttt
     1441 ttatccacga ggcgcagggg caggcgcgtc ccgtttaaaa acgccccctg cccgcgttcg
     1501 gcgtaaaaac attcgccgct gaccgggttg tagattacgc ccaattcggc gcgcccgttg
     1561 cggacaaacg ccaccgacac ggcaaaatgc ggcagcccgt tgacaaaatt gttcgtcccg
     1621 tctatcggat cgacaatcca cagccccttt tctcccgaat attccgccca caaagccgac
     1681 tgctcctgcc gcgacatttc ctcgcccaac atcgggcaat cgatcagaag cggcaacgcg
     1741 gcggcaaaag ccgtctgcgc ggcaatgtcc gcctcgctca acatcgaacc gtcttccttg
     1801 cggtgagacg gcgtattcaa aaaacgcggc ataatttcgg tttgcgcgat atggcgcacg
     1861 actttctgca aacggtgtaa cacttcctac tgtcctcata ttttgaactt gcggcacgcg
     1921 aacgtatata gtggattaaa tttaaatcag gacaaggcga cgaagccgca gacagtacaa
     1981 atagtacggc aaggcgaggc aacgctgtac tggtttaaat ttaatccact ataatgtccg
     2041 tttccatcac gccgctgcga cagattataa ccgtccgaac cgccaaaaac tatgccccga
     2101 ttccacctgc ccgaaaacct ttccgtcgga caaaccgtcg ccctgcccga caacatcgtc
     2161 cgccacctca acgtcctgcg cgtccgcccc aacgaaaaca tcaccctctt cgacggcaaa
     2221 ggcaaggcac acgccgcacg gctgaccgtt ttggaaaaac gccgcgccga agccgaaatc
     2281 ctgcacgaag acacaaccga caacgagtcc ccgctcaaca tcacactgat acaatccatc
     2341 tcctccggcg atcgcatgga tttcaccctg caaaaaagcg tcgaactcgg cgtaaccgcc
     2401 atacagcccg tcatcagcga acgctgcatc gtccgcctcg atggggaacg cgccgccaaa
     2461 cgcctcgcac gctggcagga aatcgtcatc tccgcgtgcg aacaaagcgg caggaacacc
     2521 gttccccccg tgctgcccat catcggctat cgtgaagcac tcgacaaaat gccgtctgaa
     2581 agcaccaagc tgattatgag catcaaccgc gcccgcaaac tcggcgacat ccgccacccg
     2641 tccggcgcaa tcgtctttat ggtcgggccc gaaggcggct ggacagaaca ggaagaacaa
     2701 caggcatttg aagctggctt tcaggcggtt acactcggca aacggatttt acgcacagaa
     2761 accgccccac tcgccgccct cgccgccatg cagacgcttt ggggcgattt cgcataaaca
     2821 gaaatgccgt ctgaaacccg ttcagacggc attttgcagc cgattaagat agtaggttca
     2881 aataagattt cccgtgtcgt cattcccgcg aaagcgggaa tctagaaatt taacgttgcg
     2941 gtgatttatc ggaaatgact gaaactcaac ggactggatt cccgcctgcg cgggaatgac
     3001 gaattttagg ttgctgtttt caggtttctg tttttggttt tctgttctcg cgggaataac
     3061 ggaattttaa gttttaggaa tttgtcggaa aaacagaaat cccccccgcc gtcattcccg
     3121 caaaagcggg aatctagaaa cgaaaaacta cagggattta tccgaaacaa caaaccctct
     3181 ccgccgtcat tcccgcgcag gcaggaatct agaattttaa tgcggcaaga atttatcgga
     3241 aaaaaccgaa gtttaaagac ctagattccc gcctgcgcga gaatgacgag attttaggtt
     3301 tctgtttttg gctttctgtt ttctcgggaa tcacgaatta gggcttaccc gaaaacaagt
     3361 gaaaccgaac aaaccggatt ccccgacata aatttaggga cagcgcacac ccgccaaata
     3421 aggaaaggcc aaaacctatt caaacgggac gacgtgccgc ccgaggtgtt tttccaattt
     3481 tttctgacgt ttccgttccc tcgccctttc gatttccctg ccgatttttc ccaaagcgcg
     3541 tttcaacaaa accttcgggg agcggcggtt gcggtacgat tcctgcctgc cgtttttcag
     3601 ttggctgggc agggtttcgc tttggatgca caaggcgggg gtcagttggc aaaccgtcat
     3661 cccccctttg tcgagaaaac tgctgaacag catccaatcc accgccttca ggcgttcgga
     3721 cggcaaaacg gcaaacctgt ccaaaaaaaa ccgcattgcc tttcgggaaa tgatatagcc
     3781 cgccgtcccc cagtgttcgc tttccaacag cggaaaggca cgcccgcagt agtccgccac
     3841 accggagggc gaggtcagga cgtgcataaa catcgtttcc aagcggacga taaaggcgga
     3901 atcggggtca aagcgttctt gcagccaagc gtcttcggca aggaatttct ccgcaccttc
     3961 gccgagtaaa acgtcgtcct caaatacggc gatatacggc agaccttcgt ccaatgcctg
     4021 tttccacaat acggcgtggc tcataaagca ggctttttcc actccgctca aataggggtg
     4081 cgccgacaaa ccgggtacga gttccgccat tgcctgctcc agtgcttcag acggcatcag
     4141 tgcgtcgaaa aactgaaacg gaatgtcgtg cctgccgaag gtatcggcaa tgtgcgccct
     4201 gcgttctgca gcggaagcca agctgataac gtggttttgc ataatttatc ctgttttttg
     4261 tctgttggat aaagcggcgt ttttcaacgg tttttcagca atcggcgcaa aatgccgaag
     4321 tattgcctca aggtaaacag ccgccgcatc ctgccgtctg ctgcaaatac gatgtccatc
     4381 tctcctcctt ttattggaaa ggcacaatga actgttcgcg cctttgccgg cgtttttccc
     4441 tttccctgct gattttggtc aaggcgcgga tcaggcggcg tttgaatgtg ttggcggggg
     4501 aatcgcgcct ttgctgtttg cggttcagga ggcggtcgtg ttcgatcagg ctgcccaatg
     4561 cgctgttttg gtcgtgaaac ttggcataat gcagctcttg ggcgcataag gcgggattga
     4621 gctggcaaac cggcactcct tccctgtcga aaaaatcgct gaacatcatc agatcgacgg
     4681 ggtgcagccc ttcgggcggc agggcggcaa acctgtccag gaaaaaccgc atcgcttttc
     4741 gggaaatgat atagcccgcc gtcccccagt gttcgctttc caacagcgga aaggcgcgcc
     4801 cgcagtagtc cgccacgccg gagggcgagg tcaggacgtg cataaacatc gtttccaagc
     4861 ggacgataaa ggcggaatcg gggtcaaagc gttcttgcag ccaagcgtct tcggcaagga
     4921 atttctccgc gccttcgccg agtaaaacgt cgtcctcaaa tacggcgata tacggcagac
     4981 cttcgtccaa tgcctgtttc cacaatacgg cgtggctcat aaagcaggct ttttccactc
     5041 cgctcaaata ggggtgcgcc gacaagccgg ggacgagttc cgccattgcc tgttccagcc
     5101 tttcagacgg catcagtgcg tcgaaaaact gaaacgggat gccgcgcgcg ccgaaggttg
     5161 cggcaatgtg cgccctgcgt tctgcggcgg aagctaagct gataacgtgg ttttgcataa
     5221 tttatcctgt tttttgtctg ttggataaag cggcgttttt caacggtttt tcagcaatcg
     5281 gtgcaaaatg ccgaagtatt gcctcaaggt aaacagccgc cgcatcctgc cgtctgccgc
     5341 aaaatccagc cacacgccgg cgggcggcgt gtccgtccgt ttgaagcatt ggtacaaaaa
     5401 ccggcgggcg cgttcaaaat cttcttccgg caaatgtttc tccagcaatt catacgctac
     5461 tgcttttatt tggcggtatt caaggctgtc gaaccgggtt ttaaaaccca tagactgcaa
     5521 aaaatcgttt ctggcggttt tttggatgcc ttgcgcaatt tcgtgttggc ggacgctgtg
     5581 tttggatgaa acctgattgg cgtgaaggcg gtatttgacc aaggcttcgg gataataagc
     5641 cagcctgccc aatttgctga catcgtacca aaattggtaa tcttccgccc aatcccgctc
     5701 ggtgttgtaa cgcaatccgc cgtcaatgac gctgcgccgc ataatcatcg tgttgttgtg
     5761 tatggggttg ccgaaaggaa aaacggtggc aatatcttcg tgccgggtcg gctttttcca
     5821 aattttgccg tgttcgtggt gccgcgccag ccggttgccg tccttttctt ccgacaaaac
     5881 ttccagccac gcacccatcg caatgatgct gcggtctttt tccatctcgc ccacgatttt
     5941 ctcaatccaa tcgggggcgg caatatcgtc tgcatcggta cgcgcaatat atcctccccc
     6001 ccccgacttt gccaattcat ccagcccgat gtttaaagag ggaatcaggc cggaattgcg
     6061 cggctgcgcg aggatacgga tgcggccgtc ctgttcttgg aaacgccggg caatggcaag
     6121 cgtaccgtct gtcgagccgt catcgacaat caaaatatcc aagttgcgcc aagtctgatt
     6181 cacgacggcg gctaatgatt gggcgaaata tttttctacg ttgtaggcgc aaatcaatac
     6241 gctgactaaa ggctgcaatt tattctcccg ataggcacga tgccgtctga aggcttcaga
     6301 cggcatttgg actgtacaac ggttactcgc ccaaaagcgc gatgtcggct accgcgttca
     6361 tttgttctgc caaacggttc aacaggttca aacggttttg ttttacggcg gcatcttccg
     6421 ccatcaccat cacgccgtca aagaaggcat cgacttgcgg cttgacggaa gccagttcgg
     6481 acaaggcggt ttggaaattg ccttcggcga cggcggcggc gattttcggc tgcaagcctt
     6541 gcgcagcagc aaaaagggct ttttcttcgt cctgttgcaa caggctttcg ttaaccgcgc
     6601 ccaactcggc atcggctttt ttcagcaggt tttgcacgcg tttgttggcg gcggcgagcg
     6661 cggcggcttc gggcagttgt ttgaacgcgg caacggcctg cagtttggcg gtcaaatcgt
     6721 ccaaacggcg cggctgtttg gcgagtacgg cggcaacgat gtcttgcgga taatcgtttt
     6781 gcagcaacac ggcaaggcgc gcctgcataa agtcggcggt ttcagacggc gttttttcgt
     6841 tgagcaaacc tttggggaag ctgtcgaagg tcgtctgaat cagttcattc acgtccaaac
     6901 catactgcat cagcatccgc aaaataccca aggcggcgcg gcgcagggcg taggggtctt
     6961 tatcgccggt cggaatcagg ccgatgcccc aaattccgac cagggtttcc agcttgtccg
     7021 ccagtgccac ggcggcggca attttgcttt cgggcagctt gtcgccggca aaacgcggct
     7081 ggtagtgctg ctcgacggct tcggcgattt cttcggtttc gccgtccaag cgggcatagt
     7141 atttgcccat cgtgccttgc aattcgggga actcgccgac catttcggta accaaatcgg
     7201 ctttggcaag acgcgcggcg cgctcggctg cggcggcatc cgcgtccaac gctttagcga
     7261 tgtgggcggc aatgctttgc aaacgttcga tgcgttcggc ttgcgaaccg attttgttgt
     7321 ggtacaccac gtttgccagc ttgggcaggc ggctttccag agtcgctttt tggtcttgtt
     7381 tgtagaagaa ctcggcatca gacaggcgcg cgcgcaagac gcgttcgttg ccttggatga
     7441 tgtgcgacgg atcttcggtt tgcaggttgg agaccagcag gaagcggttc atcagcttgc
     7501 cgttttgatc gagcagcggg aagtattttt ggttttgctg catcgtcaaa atcaagcatt
     7561 cttgaggcac ggcgaggaag tgttcttcaa aaccggcttc caataccaca ggccattcga
     7621 ccagcgcggt tacttcgtcc agcaatgctt catcggcggc aacggtcgcg ttcagacggc
     7681 gcgcctgccc ttccaatgcc gtctgaatcg cggctttgcg ctcggcaaac gaagcgacga
     7741 ctttgccttg cccgcgcatt tgttcggcgt agctgtcggc gttttcaatg gtgatttcgc
     7801 cgttggacaa gaagcggtgt cccaaggttt gattgctgct ttgcagaccc aaaacgctga
     7861 cgtttacgat gtcgccgccg tgcagcacaa tcagcccgtg aacagggcgc acgaaggtaa
     7921 acgtgctgct gccccaacgc atcactttcg gaatcggcag ttttttcact gcggcattga
     7981 taatgtcttc caaaagttcg cccaacggtt tgccggtttg gacgtattcg taggcgtaca
     8041 cgtcctgctt gccgtcgtgg acgatggtca agtcttcgat tttcgcccct gcaccgcgtg
     8101 cgaaaccttc caaagccttg gtcggcgcac cgtcttttac ggcattcgcc acggcagggc
     8161 cttttttcac gattttctga tcggcttgca cggctttgac gtttttgact tgaaccgcca
     8221 aacggcgcgg agaagcgtag gcggtaaatt ctgccgcgcc ggctatcagt tgcgcttttt
     8281 ccaagccttc ggcaacggaa gcggcgaaat ggttgcctaa attattcagg gcttttgggg
     8341 gaagttcttc ggtaaggagt tcgattaaaa gggtttgggt catcattcgg ctttctttga
     8401 atttggttaa tctgcctgtt tataggtttc gctgtaattt tcccagccgt catccccata
     8461 aaaaccgtca accagcgggg tggcgtacaa agtggcaaca tcttcgcggt ctgccagcca
     8521 agagataatg gcttttttct cggtttctcc caagcctcgg gcaccggatt tttgaaacag
     8581 gcacgaaaaa tcgccgcaat cgcccccgcc cgccatttcc aagccgttta ccacaagata
     8641 cgcgataagc tcgtccataa agcggccgaa cgcttcggca tcgtcctcag cttggtgcaa
     8701 actgccttga acgccgaaaa tcaatgtttg aaactcgccc aaatgcagct ttttatgctg
     8761 gcggcggttc attttgtgca ggcgtttcct gcttggggtg cggaaataga caggcatgat
     8821 tttcctaaaa tatataatgg tttacggacg actgccttat cgtgccgccc gaacgtaaaa
     8881 aatcgtcgcc cccttaggca gcatttgcct tcattaaagg gaagcccagt ttttcgcggc
     8941 tttcaacata tttttgcgcc acggcgcggc tcaatgcacg aatacgtcca atataagttg
     9001 cccgctcggt tacggaaatc gcgccgcgtg cgtctaaaag attgaacgta tgccccgctt
     9061 tgagaaccag ctcgtaggca ggcaaggcga gggcggcgtt ttcttcggca agcaggcgtt
     9121 tggcttgcgc ttcgtagtcg ttgaactggc gcagcagcca atcggcatcg ctgtattcga
     9181 agttgtaggt ggattgttcg acttcgtttt ggtggtacac gtcgccgtaa gttactgtat
     9241 taccgtccag cgtttttgcc caaacgaggt catagacgtt ttccacgcct tgcaggtaca
     9301 tcgccaagcg ttcgatgccg taggtgattt cgccgagtac gggggtgcag tcgatgccgc
     9361 cgacttgttg gaaataggtg aactgggtta cttccatacc gttgagccag acttcccagc
     9421 ccaaacccca cgcaccgagg gtggggtttt cccagtcgtc ttcgacaaag cggatgtcgt
     9481 gcactttggg gtcgatgccc aattcgcgca gggagtcgag ataaaggtct tggatattgg
     9541 cgggggcggg tttgagggcg acttggaatt ggtaatagtg ttgcaggcgg ttggggttgt
     9601 cgccgtagcg gccgtctttg gggcggcggc tgggttggac gtaggcggca aaccaaggct
     9661 cgggcccgag cgcgcgcagg caggtggcgg gatgggaagt acctgcaccg acttccatgt
     9721 cgaagggttg gatgacggtg cagcctttgt ctgcccagaa tgtttgcagt ttgaagatga
     9781 tttgttggaa ggtaagcatg gcttatgatt cgataaaata aagggtttat tttactgttt
     9841 ccattgctgt ttggataggt ttatctcgaa gacagactga tttgaaaaca cggcatacat
     9901 gatatagtgg attaacaaaa accagtacag cgttgcctta gctcaaagag aacgattctc
     9961 taaggtgctc aagcaccaag tgaatcggtt ccgtactatt tgtactgtct gcggcttcgt
    10021 cgccttgtct tgatttttgt taatccacta tattttcaaa acttggaaaa ataaaaagca
    10081 cgaccaaacg gtcgtgcttt tccaaaccaa acaagtttat ttcttgtgcg aacggatata
    10141 gtccaaagtt ttgagctgtg caatcgcagc agccaatgct ttatgcgcct ccgccaaagc
    10201 cttatcgtct ttagcttggg aaatgcccgc ttctgcggct tttttcgcct cttccgcacg
    10261 tgcctgatcc atctccgcac tgcggacggc aacatccgcc aagacagtta ctttatcagg
    10321 ctgtacttcc aaaacaccgc cggaaacagc aaccaaaacc tctttatcct cgcccggaac
    10381 ggtcaaacgc aaagcccccg gccgcaccaa actcataatc ggctcgtgtc gcggataaat
    10441 accgagttcg ccctgtacag tcggaacaac gataaatgtt gcctcgcctg aatagatttt
    10501 ctgctcgcta cttaccacct caacttccat gatgctcatg ccgacctcct cagtttaagg
    10561 ttttcgcttt ctcaaccgct tcttcgatgc tgccgaccat atagaatgcc tgctcgggca
    10621 gatggtcgta ttcgccgttc aagatggctt tgaagccggc aatggtatcg cgcagggcga
    10681 catatttgcc cggagaacct gtaaacactt cggcaacgtg gaacggttgg gacaggaagc
    10741 gttggatttt acgcgcacgc attacggtca gtttgtcttc gtcagacaat tcgtccatac
    10801 ccaagatggc gatgatgtcg cgcaattctt tgtatttctg cagggtggac tgtacgccgc
    10861 gcgccacgtc gtagtgctct tgacccaaga ccatcggatc cagttggcgt gaagtagagt
    10921 caagagggtc aactgccggg taaataccca aagaggcaat atcacggctc aatacgacgg
    10981 ttgcgtccaa gtgggcgaac gttgttgccg gagacgggtc ggtcaagtcg tccgcaggta
    11041 catatacggc ttggatggaa gtaatagaac cggtttgggt agaggtaata cgctcctgca
    11101 aacgacccat ttcttcagcc aatgtcggtt ggtagcccac tgcagaaggc atacggccca
    11161 acaatgcgga tacttcggta ccagccaggg tgtaacggta gatgttgtcc acgaagaaca
    11221 atacgtcgcg gcctttgccg ttttcgtctt tttcgtcacg gaagtattcc gccatggtca
    11281 aaccggtcaa tgcgacgcgc aaacggttgc ccggaggttc gttcatctga ccgtaaacca
    11341 ttgccacttt atccaatacg ttggaatctt tcatctcgtg gtagaagtcg ttaccttcgc
    11401 gggtacgctc acccacgcct gcgaacacgg acaagccgct gtgcgctttg gcgatgttgt
    11461 tgatcaattc catcatgttc acggttttac ccacaccggc accgccgaac agacctactt
    11521 taccgccttt ggcaaacgga cacagcaagt caatcacttt aatgcccgtt tcgagcaatt
    11581 cggttgtgga agacagttcg tcaaacttag gggcggcttg gtggatggca cggctcttgt
    11641 cggtatcaat cggacctgct tcgtcaacag gcgttcccaa tacatcgaca atgcgtccca
    11701 acgtaccttt acctaccggc acagtaatgg gcgcaccggt attgctcaca gtcatgccgc
    11761 gtttcaaacc gtccgagctg cccatcgcaa tggtacggac tacgccgtcg cccaaaagct
    11821 gttggacttc caaagtcaga ccgttttcgt ctaatttcaa agcgtcgtaa acgcgcggaa
    11881 tcatgtcgcg tggaaattcc acgtcaacaa ccgcaccgat aatttgtacg attttgcctt
    11941 ggctcattat cgtatcctaa tttctgtaca ggattcagac ggcatcagac agccgccgca
    12001 cctgctacaa tttctgacaa ttccgtggta atcgcagctt gacgcgattt gttatatacc
    12061 agacgcaact ctttgatggc attgcctgca ttgtctgttg cagctttcat ggcaaccatg
    12121 cgggctgcct gttcggatgc catattgtcg ctcaacgcct gataaaccac agactctaaa
    12181 tagcggcgaa ccagatattc caacactgca agtgcagtcg gttcgtagcg gtattcccag
    12241 ctgaacggtg atttgggagc tgaatcgcca atcacgttct caccgatagg cagcaatact
    12301 tccattctcg gttcttgacg catggtattg acaaaacccg aatacaccag atggattctg
    12361 tcaatttcat gtttctcata ccgttggaag agttctgtca aaggtccgag cagcatttcc
    12421 atttttgggg tatcgcccaa atttacggca ctggcaacca cattcagacc aatgctctga
    12481 cacgccatca gacctttact gccaaggcat acgatttcct cttcaatacc ttgattccga
    12541 tactcttgaa cttgtgccaa aaactttttc agcacgttgg cgttcaaacc gccacacaaa
    12601 cccttatcag acgtaatcaa aataaaaccg acacgtctaa tctcccgatg agattccagt
    12661 aacggaatac catgatcggt attggtttgc gcaagatggc tcatcaccat acgcactttt
    12721 tcggcatacg gacgcgccaa acgcatccgt tcctgagtct tccgcatttt agaggttgac
    12781 accatctgca tcgctttagt gatcttttgg gtattctgaa cactgcggat tttggtgaga
    12841 atctcttttc ctactgccat ttcagactcc tttcacttca agccttatgc ctgataggcg
    12901 taagaagatt tgaaggattt catggctgct tcaagcgttt tctcgctctc gtcggacatt
    12961 gcacctgaag cattgacggc ttccaaaact tccggatgtt gggtacggac aaagctcaaa
    13021 aattcagatt caaaagccag agctttggca accggaacat cagaatacga accgttgttg
    13081 attgcccaaa gggtcaaagc catttcagcc gtattcaacg tactgaactg tttctgtttc
    13141 atcagttcgg ttacgacttc gccatgctcc aattgtttgc gcgtagcttc atccaaatcg
    13201 gatgcaaatt gcgagaaagc cgccaattca cgatattgcg ccaacgccaa acggataccg
    13261 ccacccagct ttttaatcac tttggtttgt gcagcaccgc ctacgcggga tacggaaata
    13321 ccggcattga ttgcaggacg gataccggcg ttgaagaggt cggtttccaa gaaaatctga
    13381 ccgtcggtaa tcgaaatgac gttagtcgga acgaaagcag atacgtcgcc cgcttgggtt
    13441 tcgataatcg gcaacgcggt cagagaaccg gttttgcctt ttacttcgcc gttggtcaat
    13501 ttctccactt cgtgttcatt gacacgtgct gcacgttcca acagacggga gtgcaggtag
    13561 aacacatcgc cgggataggc ttcgcggccg ggcggacggc gcaaaagcag ggaaatttga
    13621 cggtaagcca cagcctgttt ggacaaatcg tcataaacaa tcaaggcatc ttcgccgcgg
    13681 tcgcggaaaa attcacccat cgtacaaccg gagtaaggtg cgatatattg caatgccgcc
    13741 gcttcagatg cagttgcagc aaccacgatg gtatgctcca tcgcgccatg ctcttccaat
    13801 ttgcggacca cgttggcaat agaagatgct ttttgaccga tagcgacata gatacagata
    13861 acacccgtac ctttttggtt gacgatggca tccaatgcta cggccgtttt acctgtctga
    13921 cggtcgccaa taatcaactc acgctgaccg cgaccgacag gaaccataga gtcaatcgcc
    13981 ttcagaccgg tttgcatcgg ctggtcaacc gatttgcgcg caatcacgcc cggtgcgatt
    14041 ttttcgatag gggcggtcaa agttgtatta atcgggcctt tgccgtcgat aggccgaccc
    14101 aatgcatcaa cgacgcgtcc gaccagttcg cgcccgaccg gcacttccaa gatacgaccg
    14161 gtacaggtaa ccgtgtcgcc ttctttaata tgttcgtact cgcccaacac tacggcgccg
    14221 acggagtcgc gctccaggtt catcgccaag ccgaaagtgt tacccgggaa ttcgagcatc
    14281 tcaccttgca ttgcatctga caaaccatgg atgcgaacga taccgtcagt taccgaaatc
    14341 accgtaccac gagtacgcac ttcggcattt acagacagat tttcgatctt ggctttaatc
    14401 aaatcgctaa tttcagcagg attaagctgc atgaaaactc tcctaattcg tcatagtcgt
    14461 gtacaaggca ctcaatttgc cttgtacaga caaatccaaa acctgatcac ccacttcaac
    14521 ttttatgccg ccaatcagct ccggttcgat ttcgacagag attttcagct cgctgtcgaa
    14581 acgcttattc agcatttgcg ccaactcgcc gacctgtttg tcggtcaacg gataggcact
    14641 gtaaatgatg gcagatttga tatggttgaa tgataaggtc aagtcttgat attgagcata
    14701 tacttccggc aatatcgaca aacgtttctg cccggccaag acgataacaa agtttttcaa
    14761 ctccttgtct ttcaaaccga ccaaatcgat gaggatatct gctttttctg aagcattcgt
    14821 ttcaggacgg tcaatcaatg aagccacctt cccttcctga acaaccgccg caagtttttc
    14881 cagtccgccc aaccaagact caatttggtt tttttcctga gccagaccga acaatgcctt
    14941 tgcataaggt ctggcaatcg ttgcgaactc tgccataaga ttacagctcc tgtttcaggg
    15001 tatcgagcag ttttgcgtgt ttggaagcat cgacttcgct gcgcaaaata gattcggcac
    15061 ctttgacagc caacacggca acctgctcgc gcagggattc gcgtgcgcgg aacaattcct
    15121 gctccacatc ggcctttgcc tgagctgcaa tgcgcgccgc ctcggaagaa gcctgttctt
    15181 tggcttcttc gacaattttg gcggcacgtt tttcggcgtt ggcaaccatt tcggaaacct
    15241 gattacgccc ttctgccaag agttctgcaa cctttttttc agcctgctcg aaatcgcttt
    15301 taccacgctc ggcggcagcc aagccttcgg cgacttttgc ggcacgctca tccaaagctt
    15361 ttgcaatcgg cggccacacg aatttcatgg taaaccatac caaaccgaaa aagacgatga
    15421 tttgagcgaa taatgttgca ttgatattca cgttacttaa ccttcgtact ggggttaatc
    15481 aaacaggctg cgcctgtacg gaacggacga atccgtcctg attatgcacc tgcaaacggg
    15541 ttaacgaagg cgaacagcag tgcaatggcg acaccaatca agaatgcggc atcaatcaaa
    15601 ccggcaatca ggaacagttt ggtttgcagc ggaccgatca gttcgggctg acgggcagaa
    15661 gactccaaat atttagaacc gaccattgcg ataccgatag aggcacccaa tgcacccaat
    15721 gcaacgatca aaccacatgc gatagcaatc aaacccattt taaactcctt aaagaaacaa
    15781 aggttaaact acaaaaacaa actacttagg aaaatcagtg cgcatcatgt gcctgtccga
    15841 tatagacgaa cgccaacgcc atgaaaataa acgcctgcag ggtaatcacc aaaatatgga
    15901 aaatcgccca tgccaaaccg gcaataatgt ggaatacaaa cagaatcgga tccatgactt
    15961 cgacgctgcc ggaagccgcc caagcaccgc caagcaaggc tatcagcaag aataccaatt
    16021 cgcccgcata catattgccg aacaaccgca taccgtggga tacggtttta gaaagaaact
    16081 cgaccaaatt caacagaaag ttcgcaggtg cgagttttgc accgaacggc gcgctgaaca
    16141 actcgtgaaa ccagccgccc aatcctttga ttttgatgtt gtaatagata caaatcagca
    16201 acacgccgac agcgagtgcc aaagtggtgt tcaaatcggc agtcggtacg acgcgcagca
    16261 gggcgtgatg gttgccggta atgccctgcc ataccatcgg cagcaaatcg accggcagca
    16321 tatccatcgc gttcatcaga aaaatccaaa caaacagcgt cagacccaac ggcgcgacgg
    16381 cttttctaga cttttcgttg tgaatgatgc tcttacacat atcgtccaca aactcaaaca
    16441 agatttccac tgcggcctgg aaacgtccgg gaacgcctgc cgtcgctttt tttgcaccgc
    16501 gccacaacag aaagctgccg attacgccca acaggacggc aaaaaagaca gcatcaaggt
    16561 taataaacga aaaatcagca atgtttttca gtccctgacc ctgagtaaca tccgacaaac
    16621 tggtcaagct ctgcaagtgg tgcttgatgt agtcggcagc ggtaatggtt tcacctgcca
    16681 taatctttca ctctcaacaa tactaaaaaa accaaatggc tgacaccgag cagccccatc
    16741 agaaacgggg cgaacaccag cgattgatgc catattgcaa atacggcaag catggacaac
    16801 agcgacagca ctacttttaa aatctctccg aagacgaaca tcctgctttg caggaagggg
    16861 tttcccctga aaagttttaa aagtaaaact gcaacaaacg tgggaagcag gtaggacaaa
    16921 ccgccaccga ccgccgaaag gaatccggca aaaccccata cagcaaaggc aactgcggcg
    16981 catatggaca atacggcgga ttgtaggatg ataatctgct tcataaaggg aatgtttccg
    17041 cctcggattt ggggcgcggc taatataatt tagaagcctt attacgtcaa gcgacagtta
    17101 atctttgtga aacaacgtat cccaatccgc cgcgctcgcc gcctgaataa cggcgacagg
    17161 tgtcattcta acacacatta catataatta caggatatta aggagtttgt ccgcaatttc
    17221 tttacatttt taatgttctt acgtgatttg tttgctttac gtggaaataa taaaaaatca
    17281 acgcgaaatt gtagcagttt atcggtcgga ttgtcggcag tttggggaat ttgctcaata
    17341 aataaaaggt cgtctgaaaa tattttcaga cgaccttttc cgaataaagg attagcaacg
    17401 gcctgccgct ttaagcaaag cattgcattg acttttgcct ttgtgcgttc cgcctcccaa
    17461 acaaattgca tcggaagtgg taacgccgat tgtgctgatt acactggtaa catagcattg
    17521 gctcacgcgc ttacccacag ttgcggtaaa gttgatgcgt atgccttcat tgttgcggtt
    17581 gctgattttt acggcatttg ggctgacgcc caaggcaaac gcggcacgtt cctgaagttt
    17641 ctagtcggaa acggttacat tattgattga gccgcaacct gctaatgcca acgcaacgaa
    17701 cgcagccgaa acgatgatgc gtgtgttcat aatttcctcg aaaattaaaa atgaaaacag
    17761 gaaaacgatt cttacgtgaa gcagaaaaat gtcaatagaa ttatatttcc cacttacaat
    17821 ctggaaagct attctctata tttcagacgg tatatcccgc aaaattaagg tcggtaatct
    17881 atgcccaact gcttcaagat atggtcgaag gtttcgggcg tgtcgaaatg caggatgatt
    17941 ctgccttttt tatggttggc ggttttgatt tcggcgttga cacccagttt ttcagtcagc
    18001 aaatcattca ggcggccgat gtcggcggcg gcagtttttt tgggctcggg acgtttgttt
    18061 tgaagggcgg cttggctgcg gcgctcgact tcgcgcaccg accagccgtt tttgacggcc
    18121 ttttgcgcca actcgagctg ttcgacgacg ggcagggtca gcagtgcgcg ggcgtgcccc
    18181 atttcgaggc ggcgttggta aagcatttcc tgcacgggtt cgggcaggct taaaaggcgc
    18241 aggctgttgg aaatcgcgct tcggctttta ccgacggctt gggcgatggt ttcgtgggtc
    18301 agtccgaact cgtcggcaag gcgtttcaag ccttgtgctt cttcgatggg gttgaggttt
    18361 tcgcgctgga ggttttcgat caaacccatt gccaacgcgg tttcgtcgct gatggttttg
    18421 ataacggcgg ggatttcggt caggccggca atctgtgcgg cacgccaacg ccgctccccc
    18481 gcaatcagtt cgtatcggga cagtccgtgt tcgcgcacga tgacgggctg tatcacgcct
    18541 tgcgccttaa tcgaatctgc cagctcctgc aaggcttcgt catcgatttg aacacgcgcc
    18601 tgatagcggc cgggccggat atctttaacc gcaaccgtgg tcaatcggtc gccgctgctg
    18661 ttgtctgcgc cgttggcgag cagcgaatcc aaaccgcgcc ccaatccgcc ttttactttt
    18721 gccataccgc cctcccgtgc ctattcagat aggatgttaa atcggatatt ttatcggata
    18781 ttgggtgttg ccgacaattt gtatccgtat ttatcggatt tctgtttttt cactataata
    18841 gccggtttgc cgttgcaggc ggttttatgg gaaaggcgga tgatggtacg gcgtttgata
    18901 atcggcatca gtggggcgag cggtttccaa tacggcgtga aggctttgga acttttacgc
    18961 gcgcaagata tcgaaacgca ccttgtggta tcgaaaggtg cggagatggc gcgcgcttcg
    19021 gaaacggctt atgcgagaga cgaggtatat gccttggcgg acttcgtgca tccgatcggc
    19081 aatatcgggg cgtgcattgc cagcggtacg tttaaaacgg acgggatgct ggtcgccccc
    19141 tgttcgatgc ggacgcttgc ctcggtcgcg cacggcttcg gcgacaacct cttgacgcgt
    19201 gcggcggatg tggttttgaa ggaaaggcgg cggctggtgc tgatggtgcg cgaaacgccg
    19261 ctgaaccttg cccatttgga caatatgaag cgggtaacgg aaatgggcgg cgtggtgttt
    19321 ccccctgttc ctgcgatgta ccgcaaaccg cagacggcgg acgacatagt ggcgcacagt
    19381 gttgcacacg ctttgtcgct gttcggaatc gatacgccgg attcggcgga atggcaggga
    19441 atggcggatt aaaggacaaa aatgccgtct gaacacggat acggttcaga cggcatcatt
    19501 ttatacgact gccttatttg gctgcgcctt cattccatgc ggcaggggat ttgtagccct
    19561 cgaagcgttt gtgcgcgtag gctttgaacg cgtcggagtt ataggcctcg gttacgtctt
    19621 taagccattg gctgtctttg tcggcggttt tgacggcaga ccagttgaca taggcaaagc
    19681 tcggttcttg gaacagggct tcggtcagct tcatgccgct gcttatggcg tagttgccgt
    19741 tgacgacggc aaaatccacg tcggcacggc tgcgcggcag ttgcgcggct tcaagctcga
    19801 cgattttgat gtttttcagg ttctcggcga tgtccgcttt ggatgcggtc agcggattga
    19861 tgccgtcttt gagtttgatc caacccagtt cgtcgagcat caccaagacg cgggcgaagt
    19921 tggacgggtc gttgggcgcg gatacggtgc tgccgtcttt gacttcttcc agcgatttca
    19981 gcttgcctgg gtacagtccc aaaggcgcgg tcggcacttg gaagacttcg gtgatgtcca
    20041 gattgtgttc ttttttgaag tcgtcaagat agggtttgtg ttggaagacg ttgatgtcca
    20101 actcgccctc agccaatgcc agattcgggc gcacatagtc ggtaaactcg accagtttga
    20161 cggtgtagcc ttttttctcc agctcgggtt ggatttgttc tttgaccata tcgccgaagt
    20221 cgccgacggt cgtgccgaag acgatttctt ttttcgccgc gccgttgtcg gcggcggcag
    20281 aagcggatgc ggcgggcgcg ctatcttttt gaccgccgca ggcggcgagg atgagcgcga
    20341 gtgcggcggc ggaaagggtt ttgaagaagg ttttcatatt ttctcctgat gttgtggcag
    20401 tttcaaacaa aaatgacggg cagggagtcc tgccgtccgg attcggcgtt cagacggcat
    20461 ttgccgcgaa cagggggatt ttatagcatt tttcggatag cggtgggggt tttggcgttc
    20521 agacggcatt tgggttcaac gtttgtcgag tttccgcgcc aacgtgttgc cggtgctttg
    20581 aatcaggatg accagcagca cgaggagggc gacgatgaag acgatgactt cggtttggta
    20641 gcggtagtag ccgtagcgga tggcgaggtc gcccaagccg ccgccgccta tcatccctgc
    20701 cgccgcgctg tatgacaaaa gcccgatggc aagcacggta atgctggaaa ccatgcccgc
    20761 gcgcgcttcg tttaagagga ctttgcggat gatggcaacc ggcggcgcac ccatagcggc
    20821 ggcggcttca atcacgcctt tggggacttc gcgcaggttt tgttccacca aacgggcaaa
    20881 ataaaacaat cccgacacgc tcaacaccag cgaggcggca accggaccga tggtgctgcc
    20941 gacgatggcg cgtgtggcgg gtatcatcgc aatcatcaaa atgacgaagg ggaaggcgcg
    21001 catgaggttg acgaggttgt cgagcaggaa gttcaccgcc ttgttgtaat gcagttggcg
    21061 gctggaagtt acgaagagca acacgcccag caacgtgccg aaaacgacgg cgaatgtggt
    21121 ggacaagccg accatcacga aggtttcgcc caatgcgcgg acgatttcgc ctttcatacc
    21181 gatgatgttg gaaacggctt gttggaatgt taagtctgcc atatcagtcc tcccgaatca
    21241 gttcgcgccc gatgtcggat cgggcgtgga tttggttgcc gcgtacttcg acgatttcga
    21301 cgactttgcc tttgtccaac agggcggcgc ggtcgcacag tcgtctgatg acgctcattt
    21361 cgtgggttac gatgacgatg gttacgttga atcgtttgtt gatgtcttcc aaacattcca
    21421 agacgctgcg cgtggtggcg gggtcgaggg cggaagtggg ttcgtcggcg aggatgactt
    21481 ggggtttggg cgcgagtgcg cgggcgatgc cgacacgctg tttctgcccg ccggaaagct
    21541 gggcgggata gtggccggcg cgttcggtca gtccgacgat ttcgaggcat tcggcaacgc
    21601 gcgttttgat tttttcagac ggccatccgg cgatttccaa tgggaaggcg acgttgccgg
    21661 cgacggtgcg gttgttcaac aggttgaact gttgaaatac catgccgata ttctgccgcg
    21721 cctgacgcaa tgcggcggca tcaagcgcgg tcagctcttg tccgcagacg ttgaccttgc
    21781 cgctgtcggg gcgttccaac aggttaatca ggcgcaacag ggtggatttg cctgcacccg
    21841 aataacccat cagcccgaag atttcgccgt cgcggatttc gaggctggtc ggctcgacgg
    21901 cggcaaaacg ggtcttgtcg cgcgtttggt aatgcttgga aaccttgtcc aaaataatca
    21961 ttgtcttttc catacaacaa agcccgatgt cggacacaac gggcgcggaa gataaagctg
    22021 aaattgtcgg aacgctttag ctgttatgcc cgcaagctgt gtcaaatcgg caggttaatt
    22081 ttcgtaggat attatcggga aagcattttt ttgtcaataa agcaggaagc gggcaaccat
    22141 ttcggacaat gccgtctgaa acgggcaaag gcagcggttc gcaccaaaac ggcaaataat
    22201 tgaaaaacat atagtggatt aacaaaaatc aggacaaggc gacgaagccg cagacagtac
    22261 aaatagtacg gaaccgatcc acttggtgct tcagcacctt agagaatcgt tctctttgag
    22321 ctaaggcgag gcaacgccgt actggtttaa atttaatcca ctataaatta tgtcggaaac
    22381 attccaaagg cggtgcagtt tcggcatata attcgggcaa acgcctgttc agacggcatt
    22441 ttgtcttttc caaccctgac cgttcagggt tccgattctt aaggaaatcc gatgtaccta
    22501 ccctctatga agcattccct gccgctgctg gcggccctgg tgcttgccgc gtgttcttcg
    22561 acacacgcgc ccagcagcaa gaccctggca gacaatatag aaactgccgg tctttcggca
    22621 agcgttccca cccgccctgc cgaacccgaa ggaaaaacgc tggcagatta cagcagctac
    22681 ccgtccgcac tggatgcagt gaaacagaaa aacgatgccg ccgtcgccgc ctatttggaa
    22741 aacgccggcg acagtgcgat ggcggaaaat gtccgcaacg agtggctgaa gtctttgggc
    22801 gcacgcaaac agtggacgct gtttgcacag gaatacgcca aactcgaacc ggcagggcgc
    22861 gcccaagaag tcgaatgcta cgccgattcg agccgcaacg gctatacgcg tgccgccgaa
    22921 ctggttaaaa atacgggcaa actgccttcg ggctgcacca aactgttgga acaggcagcc
    22981 gcatccggct tgttggacgg caacaatgcc tggaggcgcg tgcgcggact gctggccggc
    23041 cgccaaacca cagacgcacg caaccttgcc gccgcattgg gcagcccgtt tgacggcggc
    23101 acacaaggtt cgcgcgaata tgccctgttg aacatcatcg gcaaagaagc acgcaaatcg
    23161 ccgaatgccg ccgccctgct gtccgaaatg gaaagcggtt taagcctcga acaacgcagt
    23221 ttcgcgtggg gcgtattggg gcattatcag tcgcaaagcc tcaatgtgcc tgccgccttg
    23281 gactattacg gcaaggttgc cgaccgccgc caactgaccg acgaccaaat cgagtggtac
    23341 gcccgcgccg ccttgcgcgc ccgacgttgg gacgagctgg cttccgtgat ctcgcatatg
    23401 cccgaaaaac tgcaaaaaag cccgacctgg ctctactggc tggcacgcag tcgcgccgca
    23461 acgggcaaca cgcaagaggc ggagaaactt tacaaacagg cggcagcaac gggcaggaat
    23521 ttttatgcgg tgctggcggg ggaagagttg gggcgcaaaa tcgatacgcg caacaatgtt
    23581 cccgatgccg acgcaaacag cgtcctccgt atggcggaag acggcgcgat taagcgtgcg
    23641 ctggtgctgt tccgaaacag ccggaccgcc ggcgatgcga aaatgcgccg tcaggctcag
    23701 gaggaatggc gtttcgccac acgcgggttc gacgaagaca agctgctgac cgccgcacaa
    23761 accgcgttcg accacggttt ttacgatatg gcggtcaaca gcgcggaacg caccgaccgc
    23821 aaactcaact acaccttgcg ctacatttcg ccgtttaaag acacggtaat ccgccacgcg
    23881 caaaatgtta atgtcgatcc ggcgtgggtt tacgggctga ttcgtcagga aagccgcttc
    23941 gttatgggcg cgcaatcccg cgtaggcgcg caggggctga tgcaggttat gcctgccacc
    24001 gcgcgcgaaa tcgccggcaa aatcggtatg gatgccgcac aactttacac cgccgacggc
    24061 aatatccgta tggggacgtg gtatatggcg gacaccaaac gccgcctgca aaacaacgaa
    24121 gtcctcgcta ccgcaggcta caacgccggt cccggcaggg cgcgccgatg gcaggcggac
    24181 acgcccctcg aaggcgcggt atatgccgaa accatcccgt tttccgaaac gcgcgactat
    24241 gtcaaaaaag tgatgaccaa tgccgcctac tacgccagcc tcttcggtgc gccgcacatc
    24301 ccgctcaaac agcgtatggg cattgtcccc gcccgctgac gtaccgatgc cgtctgaaac
    24361 ccgcccggtc tttcagacgg catttttatc ccgaacggca ttgacggcga accataaata
    24421 taagacaatc cgaaaattgt ttttcctgct ttttcaagca gcttgacacg gcacaagccg
    24481 acccgttagg aggtgatgtt tccgtcacgg cgcgtatccc gccgccgcaa ggcacagcga
    24541 tacggtaaac cttcaacacc gtctgcccta ccctttccac cgatatgatg ggcagatgca
    24601 acaaccgaat ttattaaagg aaataaaatg cctgcaatcc gcgtaaaaga gaatgaacca
    24661 tttgaagtcg ctatgcgccg tttcaaacgc gccgtagaaa aaaccggcct gctgaccgag
    24721 ctgcgcgccc gcgaagccta cgaaaaaccg actaccgaac gcaaacgcaa aaaagcggca
    24781 gccgtaaaac gcctgcaaaa acgcctgcgc agccaacaac tgccgcccaa aatgtactaa
    24841 acgttcaagt acagattaca ggtcagccct gtgatatgag gacacaccgc aagacctgct
    24901 ctgcggtgtg ttttgctttt cagacggcat cgaaacccgc cgtttccatc cgacatccca
    24961 gcgaggacat tatgagcctg aaaatccgcc ttaccgaaga catgaaaacc gcgatgcgcg
    25021 ccaaagacca agtttccctc ggcaccatcc gcctcatcaa cgccgccgtc aaacagtttg
    25081 aagtggacga acgcaccgaa gccgacgatg ccaaaatcac cgccatcctg accaaaatgg
    25141 tcaaacagcg caaagacagc gcgaaaatct acactgaagc cggccgccag gatttggcag
    25201 acaaagaaaa cgccgaaatc gaggtactgc accgctacct tccccaaatg ctctctgccg
    25261 gcgaaatccg tactgcggtc gaagccgccg ttgccgaaac cggcgcggca ggtatggcgg
    25321 atatgggcaa agtgatgggc gtattgaaaa cccgacttgc cggcaaagcc gatatgggcg
    25381 aagtcaacaa aatcctgaaa gccgtactga ccgcctgatt gcccgaatat cggacaaaat
    25441 gccgtctgaa gcccgtatcg caggttcaga cggcattttc atggtttgat gatatttata
    25501 aaaattttgc aacacgctca tgcacagcaa ctgccgctgc tcgttggcgt tgccgctcta
    25561 tcgcttggtt agctgcacca taattgcact ctaatgctga tgcaataacg tcccaatatc
    25621 gaattggcag gggcaacacg gtttcgatac accgaaacgg gttttgccga taaacggatt
    25681 ccgtttgcgc cccatcggac aaaatgccgt ctgaaacacg attccgttca gacggcatag
    25741 atttatttga ccaatttcaa gccttttttg gcgggccggg gcgcggtttc ggcagaggtg
    25801 ttttcaggcg gcgtgtcggg gcgatacgct tccaattcaa accccatacc ttcgccggtc
    25861 tcccgtgcga aaaggctgag gacgtgtccg acaggtatcc atatatcgtg cgcctgtccg
    25921 ccgaagcggg cggaaaaact gatccaatcg ttgtcgattt gaaggttttg cgtggcggtc
    25981 gcgccgatgt tgagcataat ttcgttgtcg cggacgtact gcatggggac gcgcgtgtgt
    26041 tcgttgaccc agacaaggat gtgcggtgtg aggctgttgt cgctgcacca ttcgcagagg
    26101 gcgcggagga tgtagggttt ggtggaagtg ggcataatgg gttccgtgtt gtacgccaaa
    26161 ataggaaaat gcctgcaaaa cggcgggttt tgcaagcatt tcggacttat ttgcgcatgg
    26221 ctttttcggc gggtgtcagt gcttcgataa aggcttcgcg ctggaagatg cgctcggcgt
    26281 atttgagcag cggcgcggca cttttgccca gtttgacatc gtagtggtcg agccgccaca
    26341 gcagcggagc aagggcgaca tcaatcatag agaaatcttc gccgaggatg tatttgcttt
    26401 tgctgaacga aggggcaagc atggtcagac cgttgccgat ggcttcgcgc gcttttgcct
    26461 gttccttgtt ggtggcggcg gggttttcca aaacttggac gtggttgaac aattcttttt
    26521 ccatacggta cagcaccagc cggcccctgc cgcgcataac gggatcgccg ggcataagct
    26581 gcggatgggg gaagcgttcg tcgatgtatt cgttgatgat gttggactcg tgcagcacca
    26641 aatcgcgttc gaccagcaca gggacttggt tatacgggtt catgacggcg aggtcttcgg
    26701 gtttgttgta aatatcgacg tctttgattt caaaatccat acctttttcg tacaaaacga
    26761 aacggcagcg gtggctgaag gggcaggtaa tgccggaata gagggtcatc ataataattg
    26821 tcgctcctgt gtgatgcctg taaaacggct gat
//
LOCUS       DAXIDM010000014        26469 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000014 DAXIDM010000000
VERSION     DAXIDM010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 26469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26469
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.014"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(423..1490)
                     /gene="murG"
                     /locus_tag="ACFOAE_000507"
     CDS             complement(423..1490)
                     /gene="murG"
                     /locus_tag="ACFOAE_000507"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFC6884059.1"
                     /translation="MGGKTFMLMAGGTGGHIFPALAVADSLRARGHHVIWLGSKDSME
                     ERIVPQYGIRLETLAIKGVRGNGIKRKLMLPVTLYQTVREAQRIIRKHRVECVIGFGG
                     FVTFPGGLAAKLLGVPIVIHEQNAVAGLSNRHLSRWAKRVLYAFPKAFSHEGGLVGNP
                     VRADIAKLPAPAERFQGREGRLKILVVGGSLGADVLNKTVPQALALLPDNARPQMYHQ
                     SGRGKLGSLQADYDALGVKAECVEFITDMVSAYRDADLVICRAGALTIAELTAAGLGA
                     LLVPYPHAVDDHQTANARFMVQAEAGLLLPQTQLTAEKLAEILGGLNREKCLKWAENA
                     RTLALPHSADDVAEAAIECTA"
     gene            complement(1494..2819)
                     /locus_tag="ACFOAE_000508"
     CDS             complement(1494..2819)
                     /locus_tag="ACFOAE_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFC6884060.1"
                     /translation="MQTDWQVVFLKISEVLVKVGDGVHTLLLDRPIVRDGRKFDAPLL
                     WMVVLMTAFSLLMIYSASVYLASKEGGDQFFYLTRQAGFVVAGLIASGFLWFLCRMRT
                     WRRLVPWIFALSGLLLVVVLIAGREINGATRWIPLGPLNFQPTELFKLAVILYLASLF
                     TRREEVLRSMESLGWQSIWRGTANLIMSATNPQARRETLEMYGRFRAIILPIMLVAFG
                     LVLIMVQPDFGSFVVITVIAVGMLFLAGLPWKYFFVLVGSVLGGMVLMITAAPYRVQR
                     VVAFLDPWKDPQGAGYQLTHSLMAIGRGEWFGMGLGASLSKRGFLPEAHTDFIFAIIA
                     EEFGFFGMCVLIFCYGWLVVRAFSIGKQSRDLGLTFNAYIASGIGIWIGIQSFFNIGV
                     NIGALPTKGLTLPLMSYGGSSVFFMLISMMLLLRIDYENRRKMRGYRVE"
     gene            complement(2945..4282)
                     /gene="murD"
                     /locus_tag="ACFOAE_000509"
     CDS             complement(2945..4282)
                     /gene="murD"
                     /locus_tag="ACFOAE_000509"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFC6884061.1"
                     /translation="MTLENKKILVAGLGGTGISMIAYLRKNGAEVAAYDAELKPERVS
                     QIGKMFDGLVFYTGRLKDALDNGFDILALSPGISERQPDIEAFKQNGGRVLGDIELLA
                     DIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAEWQREGKK
                     ADVWVLELSSFQLENTESLSPTAATVLNISEDHLDRYDDLLDYAHTKAKIFRGDGVQV
                     LNADDAFCRAMKRAGREVKWFSLEHEADFWLERETGRLKQGNEDLIATKDIPLQGLHN
                     AANVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGKKNGVVFIDDSKGTNVGAT
                     AAAIAGLQNPLFVILGGMGKGQDFTPLRDALAGKAKGVFLIGVDAPQIRRDLDGCGLN
                     MTDCATLEEAVQTAYAQAEACDIVLLSPACASFDMFKGYAHRSEVFIEAFKAL"
     gene            complement(4372..4644)
                     /locus_tag="ACFOAE_000510"
     CDS             complement(4372..4644)
                     /locus_tag="ACFOAE_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HFC6884062.1"
                     /translation="MKQTVKWLAAALIALGLNQAVWADDVSDFRENLQAAAQGNAAAQ
                     YNLGAMYYKGRGVRQDLVLAQEWFGKACQNGDQDGCDIYQRLKAGY"
     gene            complement(4759..5841)
                     /gene="mraY"
                     /locus_tag="ACFOAE_000511"
     CDS             complement(4759..5841)
                     /gene="mraY"
                     /locus_tag="ACFOAE_000511"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFC6884063.1"
                     /translation="MFLWLAHFSNWLTGLNIFQYTTFRAVMAALTALAFSLMFGPWTI
                     RRLTALKCGQAVRTDGPQTHLVKNGTPTMGGSLILTAITVSTLLWGNWANPYIWILLG
                     VLLATGALGFYDDWRKVVYKDPNGVSAKFKMVWQSSVAVIAGLALFYLAANSANNILI
                     VPFFKQIALPLGVVGFLVLSYLTIVGTSNAVNLTDGLDGLATFPVVLVAAGLAIFAYV
                     SGHYQFSQYLQLPYVAGANEVAIFCTAMCGACLGFLWFNAYPAQVFMGDVGALALGAA
                     LGTVAVIVRQEFVLVIMGGLFVVEAVSVMLQVGWYKKTKKRIFLMAPIHHHYEQKGWK
                     ETQVVVRFWIITIVLVLIGLSTLKIR"
     gene            complement(5934..6110)
                     /locus_tag="ACFOAE_000512"
     CDS             complement(5934..6110)
                     /locus_tag="ACFOAE_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884064.1"
                     /translation="MKSRRFFKALLLIAALVGAFYAGMRTQAYLYEDLCLDLGGGKNP
                     GSYPICVIEKVPAR"
     gene            complement(6113..7471)
                     /gene="murF"
                     /locus_tag="ACFOAE_000513"
     CDS             complement(6113..7471)
                     /gene="murF"
                     /locus_tag="ACFOAE_000513"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFC6884065.1"
                     /translation="MKPLDLNFICQALKLPMPSESKLVSRIVTDSRDSRAGDVFFALA
                     GGRFDAHDFVEDVLAAGAAAVVVSREDCVAMDGALKVDDTLTALQMLAKAWRDNVNPF
                     VFGITGSGGKTTVKEMLAAVLRRRFGDDAVLATAGNFNNHIGLPLTLLKLNEKHRYAV
                     IEMGMNHFGELAVLTQIAKPNAALVNNAMRAHVGCGFDGVGDIAKAKSEIYQGLCSDG
                     IALIPQEDANMAVFKTATLNLNTRTFGVDSGDVHAENIVLKPLSCEFDLVCGNERTAV
                     VLPVPGRHNVHNAAAAAALSLAAGLSLNDVAEGLKGFSNIKGRLNVKSGIKGATLIDD
                     TYNANPDSMKAAIDVLARMPAPRIFVMGDMGELGEDEAAAMHAEVGAYARDQGIEAAY
                     FVGDNSVEAAEKFGADGLWFAAKDPLIQVLRHDLPERATVLVKGSRFMEMEEVVEALE
                     DK"
     gene            complement(7596..9239)
                     /locus_tag="ACFOAE_000514"
     CDS             complement(7596..9239)
                     /locus_tag="ACFOAE_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFC6884066.1"
                     /translation="MKQSARIKNMNQTLKNTLGICALLAFCFGAAIASGYHLEYEYGY
                     RYSAVGALASVVFLLLLARGFPRVSSVVLLIYVGTTALYLPVGWLYGAPSYQIVGSIL
                     ESNPAEAREFVGNLPGSLYFVQALFFIFGLTVWKYCVSGVFADVKNYKRRSKIWLTIL
                     LTLILSCAVMDKIASDKDLREPDAGLLLNIFDLYYDLASAPAQYAAKRAHILEAAKKA
                     STWHIRHVAPKYKNYVVVIGESARSDYMNVYGFPLPDTPFLSQTKGLLINGYQSTAHA
                     TNLSLPQTLGLPGEPNNNIVSLAKQAGFRTAWLSNQGMLGHFANEISTYALRSDYPWF
                     TQRGDYGKSAGLSDRLLLPAFKRVLIGNAGTKPRLIVMHLMGSHSDFCTRLDKDARRF
                     QYQTEKISCYVSTIAQTDKFLEDTVKILNENKESWSLVYFSDHGLMHVGKGGERTLTH
                     GAWKRQSYGVPLVKISSDDTRREMIKVRRSAFNFLRGFGSWTGIETDELPDDGYDFWG
                     NVPDVQGEGNNLAFIDGLPDDPAPWYAGKGKSTKNTSKK"
     gene            complement(9262..10740)
                     /locus_tag="ACFOAE_000515"
     CDS             complement(9262..10740)
                     /locus_tag="ACFOAE_000515"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HFC6884067.1"
                     /translation="MFSKLTPLAETGIPPLPCANAAGRLLHSDSRQIKQGDIFVACPG
                     EYADGRSYIPAAVANGAAFVFWDDDGKFAWNPEWKVPNQGIRDLKHRAGILAAQVYGN
                     VSDGLKVWGVTGTNGKTSITQWLAQAADLLGEKTAIIGTVGNGFWGALEETTHTTPAP
                     VDVQTLLYRFRQQGATAAAMEVSSHGLDQSRVNGVPFCSAIFTNLTRDHLDYHGTMEA
                     YGAIKSRLFYWHGLQHAVINVDDEYGAELVGRLKKDCPDLVVYSYGFSEHADIRITDF
                     TASSDGIAAVFQTPWGEGKCRTRLLGRFNAQNLAACIALLCANGYPLDKVLDVLAKIR
                     PASGRMDCIMNSGKPLVVVDYAHTPDALEKALATLQEIKPQGAALWCVFGCGGNRDRG
                     KRPLMGAAAVQGADKVVVTSDNPRLENPHDIINDILPAVPAPECVEADRAAAIRYAVE
                     QAAANDIILIAGKGHENYQDVQGVKHRFSDLEIVGQALLTRK"
     gene            complement(10765..12510)
                     /locus_tag="ACFOAE_000516"
     CDS             complement(10765..12510)
                     /locus_tag="ACFOAE_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFC6884068.1"
                     /translation="MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIA
                     RGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSDRNGAVLALSAPTESLFAVPKEM
                     KEMPSAAQLERLSELVDVPIDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFV
                     FEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIV
                     DSLDSPRNKAPKNGKDIILSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEIL
                     ALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKALDAGKTDLNERLNT
                     QPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRM
                     HSGFPGETAGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFE
                     KQAVAPQGKRIFKESTAREVRNLMVSVTEPGGTGTAGAVDGFDVGAKTGTARKLVNGR
                     YVDYKHVATFIGFAPAKNPRVIVAVTIDEPTANGYYGGVVTGPVFKQVMGGSLNILGV
                     SPTKPLTAAAVKTPS"
     gene            complement(12571..12834)
                     /gene="ftsL"
                     /locus_tag="ACFOAE_000517"
     CDS             complement(12571..12834)
                     /gene="ftsL"
                     /locus_tag="ACFOAE_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFC6884069.1"
                     /translation="MNKLNFLLLLAVCVSAFSVVMQQNQYRLNFTALDKAKKQEIALE
                     QDYAQMRLQQARLANHEAIRAAAEKQNLHPPVSGNTFMVAHQR"
     gene            complement(12831..13817)
                     /gene="rsmH"
                     /locus_tag="ACFOAE_000518"
     CDS             complement(12831..13817)
                     /gene="rsmH"
                     /locus_tag="ACFOAE_000518"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFC6884070.1"
                     /translation="MSGAESYRHITVLLNEAVDALAVREDGVYVDGTFGRGGHSRLIL
                     SRLGDAGRLIVFDKDPQAIAVAEELARSDKRVGVVHGGFASFQTALDGLGIGKVDGAL
                     FDLGISSPQIDDGSRGFSFRFDAPLDMRMDTTRGMSAAEWIAVASEQDLHEVIKNYGE
                     ERFSRQIARAIVAQRAESPIDTTRKLAQIVAQNVRTRERGQDPATRTFQAIRIFINRE
                     LEEVGAVLPQVMCRLKEGGRLAVIAFHSLEDRIVKQFVKKYSQHAPLPRWAAVREADL
                     PEPPLKIAGRALKPGEAEIAANPRARSAVLRVAERTAGPIPEQSQRKTSEWQ"
     gene            complement(13814..14269)
                     /gene="mraZ"
                     /locus_tag="ACFOAE_000519"
     CDS             complement(13814..14269)
                     /gene="mraZ"
                     /locus_tag="ACFOAE_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFC6884071.1"
                     /translation="MFGGAHELSIDSKGRLAVPAKFRDILSRLYTPAVVVTLESKHKL
                     LMYPVAEWEKVAAQLLNLKVADNPVLRRFQNLLLHNAEILEWDSAGRVLLPAGLRKRV
                     DFDREVVLVGRANRLELWGREQWEAEMVQALDDDPDELAFQLGQTDLQL"
     gene            14548..15765
                     /locus_tag="ACFOAE_000520"
     CDS             14548..15765
                     /locus_tag="ACFOAE_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC6884072.1"
                     /translation="MTAPAPTCNMSGNPINLHKLTLIMPLPLPSPEARQFSLKLQTLI
                     AEKIGKHGNWIPFSRFMELVLYAPQYGYYTGGSHKIGNTGDFITAPTLTSLFAQTLAR
                     QLQELLSQTAGNIYEFGAGTGQLAADLLGSISDGISRYYIIEISPELAARQKNLIQAR
                     APEASQKVVHLTALPEAFDGIIIGNEVLDAMPVEIVRKNEGGSFEHVGVCLDNDRFTY
                     SARPLHDLQLSALASLYFPQTDYPYTSELHPQQYAFIRTLASRLERGGMIFIDYGFDA
                     AQYYHPQRNQGTLIGHYRHHVIHNPFDFIGLADLTAHVNFTDIAQAGTDAGLDLIGYL
                     PQSHFLLNLGITELLAQTGKTDSAAYIREAAAVQKLIDQHEMGELFKVIAFGKNIGID
                     WAGFRFGDICHKL"
     gene            15897..15973
                     /locus_tag="ACFOAE_000521"
     tRNA            15897..15973
                     /locus_tag="ACFOAE_000521"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15931..15933,aa:Met,seq:cat)
     gene            15981..16056
                     /locus_tag="ACFOAE_000522"
     tRNA            15981..16056
                     /locus_tag="ACFOAE_000522"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16014..16016,aa:Ala,seq:ggc)
     gene            complement(16243..17064)
                     /locus_tag="ACFOAE_000523"
     CDS             complement(16243..17064)
                     /locus_tag="ACFOAE_000523"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFC6884073.1"
                     /translation="MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIDFHSNHK
                     VFEITIQLGAVLAVVFEYRQRFSNVLHGVGKDRKANRFVLNLAIAFIPAAVMGLLFGK
                     QIKEYLFNPLSVAVMLVLGGFFILWVEKRQSRAEPKIVDVDALRPIDALMIGVAQVFA
                     LVPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVG
                     LILIGFIAAFVSGLVAVKALLKFVSKKNYIPFAYYRIVFGIVIIILWLSGWISWE"
     gene            complement(17097..17741)
                     /locus_tag="ACFOAE_000524"
     CDS             complement(17097..17741)
                     /locus_tag="ACFOAE_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC6884074.1"
                     /translation="MKLKHLLPLLLSAVLSAQAYALTEGEDYLVLDKPIPQKQSGKIE
                     VLEFFGYFCVHCHHFDPLLLKLGKALPSDAYLRTEHVVWQPEMLGLARMAAAVKLSGL
                     KYQANPAVFKAVYEQKIRLENRSVAEKWALSQKGFDGKKLMRAYDSPAAAAAASKMQQ
                     LTEQYRIDSTPTVVVGGKYRVIFNNGFDGGVHTIKELVAKVREERKRQTPAVQK"
     gene            complement(17744..18607)
                     /gene="ftsN"
                     /locus_tag="ACFOAE_000525"
     CDS             complement(17744..18607)
                     /gene="ftsN"
                     /locus_tag="ACFOAE_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HFC6884075.1"
                     /translation="MNKFSQSGKGLSGFFFGLILATVIIAGILFYLNQSGQNAFKIPV
                     PSKQPAETEILKPKNQPKEDIQPEPADQNALSEPDAAKEAEQSDAEKAADKQPVADKA
                     DEVEEKADEPEREKSDGQAVRKKALTEEREQTVGEKAQKKDAETVKKQAVKPSKETEK
                     KASKEEKKAEKEKVAPKPTPEQILNSGSIEKARSAAAKEVQKMKTPDKAEATHYLQMG
                     AYADRRSAEGQRAKLAILGISSKVVGYQAGHKTLYRVQSGNMSADAVKKMQDELKKHE
                     VASLIRSIESK"
     gene            complement(18713..20209)
                     /locus_tag="ACFOAE_000526"
     CDS             complement(18713..20209)
                     /locus_tag="ACFOAE_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HFC6884076.1"
                     /translation="MSLALVYSRALSGMNAPLVEVEAHLANGLPHFNIVGLPDTEVKE
                     SRDRVRAAIIQSGFEFPAKKITVNLAPADLPKESGRFDLPIAIGILAASGQVAPEKLA
                     EYEFAGELALSGLLRPVRGALAMAWQGMQAKRAFVLPEENAGQAAVMRGITVYGARSL
                     GEVAAHLNGIEPLAQTECQVPQMPFEHGGQPDLCDVKGQHTARLALEIAAAGGHSLLM
                     MGPPGTGKSMLSQRLPGILPPLTEDELVEVWALRSLLPNHQQQLDSNRPFRSPHHSAS
                     AAAMVGGGSDPRPGEISLAHHGVLFLDELPEFDRKVLEVLREPLENGEIHISRAARQA
                     VYPAKFQLVAAMNPCPCGYLGHPVKPCRCTPESVARYRSKISGPLLDRIDLTIEVPSL
                     SAAELMQQEAGESSASVLERVIAARDKQYARQGKVNAALSVSELDSQARIQKEAQEAL
                     GGLMEKLSLSARSFHRIMRVARTLADLAGDEEVGRSHVMKAIGFRRAL"
     gene            complement(20223..20543)
                     /locus_tag="ACFOAE_000527"
     CDS             complement(20223..20543)
                     /locus_tag="ACFOAE_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003763371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory factor UbiK family protein"
                     /protein_id="HFC6884077.1"
                     /translation="MFGKQLFEEVGSKISETIANSPAKDVEKNIKSMLGGAFNRMDLV
                     TREEFDIQQQVLIKTRTKLAALEARLAKLEAAQNPERAALEAAEAAAEEAVAEIRQQT
                     EAGE"
     gene            21026..22552
                     /gene="putP"
                     /locus_tag="ACFOAE_000528"
     CDS             21026..22552
                     /gene="putP"
                     /locus_tag="ACFOAE_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005298 - proline:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0031402 - sodium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0015824 - proline transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HFC6884078.1"
                     /translation="MNPMYITFAIYLVAVLLIGLAAYFSTRNFDDYILGGRSLGPFVT
                     AMSAGASDMSGWLLMGLPGAIYLSGLNEAWIAIGLLVGAYFNWLLVAGRLRVHTEYAN
                     NALTLPDYFFHRFGAGGHLMKVVSALIILFFFTIYCASGIVAGATLFQSLFEGMTYNQ
                     AMWLGAGATIAYTFLGGFLAVSWTDTLQASLMIFALILTPVMVYLGLGGAEQMSAAIQ
                     SVAAGTGKEYGSLFAGTTVIGIISTAAWGLGYFGQPHILARFMAAESAKSLVSARRIG
                     MTWMALCLAGAVAVGYFGIAYFGANPDKVSSMSGNHERIFIALSTLLFNPWIAGIILS
                     AILAAVMSTLSCQLLVCSSAITEDFYKGFLRKNAQQSELVWVGRLMVLAIAVISILIA
                     SDPNSKVLGLVSYAWAGFGAAFGPIVILSVLWKRITAYGALSGMVAGALTVVVWAEWV
                     KKPAQAAGESGLLTMYEIVPGFIVCLIIAVLVSLFNKEPSREIQERFEKADADYRAAR
                     "
     gene            complement(22642..22809)
                     /locus_tag="ACFOAE_000529"
     CDS             complement(22642..22809)
                     /locus_tag="ACFOAE_000529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884079.1"
                     /translation="MKHFLDSPKFFGGQAASVRPEYGNIVINPQMKYKASNAGRVGAS
                     VSLKMKRVKHK"
     gene            22801..26406
                     /gene="putA"
                     /locus_tag="ACFOAE_000530"
     CDS             22801..26406
                     /gene="putA"
                     /locus_tag="ACFOAE_000530"
                     /EC_number="1.2.1.88"
                     /EC_number="1.5.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0004657 - proline dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0010133 - proline catabolic process to
                     glutamate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional proline dehydrogenase/L-glutamate
                     gamma-semialdehyde dehydrogenase PutA"
                     /protein_id="HFC6884080.1"
                     /translation="MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNA
                     ASELARRLVTQVRAGRTKAGGVDALMHEFSLSSEEGIALMCLAEALLRIPDNATRDRL
                     IADKISDGNWKSHLNNSPSLFVNAAAWGLLITGKLTATNDKQMSSALSRLISKGGAPL
                     IRQGVNYAMRLLGKQFVTGQTIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYY
                     RDYVEAIHAIGKDAAGQGVYEGNGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLL
                     GKKYDIGINIDAEEANRLELSLDLMEALVSDPDLAGYKGIGFVVQAYQKRCPFVIDYL
                     IDLARRNNQKLMIRLVKGAYWDSEIKWAQVDGLNGYPTYTRKVHTDISYLACARKLLS
                     AQDAVFPQFATHNAYTLGAIYQMGKGKDFEHQCLHGMGETLYDQVVGPQNLGRRVRVY
                     APVGTHETLLAYLVRRLLENGANSSFVNQIVDENISIDTLIRSPFDTIAEQGIHLHNA
                     LPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQMNKAAAQDFHAASIVNGKARDVGEAQ
                     PIKNPADHDDIVGTVSFADAALAQEAVGAAVAAFPEWSATPAAERAACLRRFADLLEQ
                     HTPALMMLAVREAGKTLNNAIAEVREAVDFCRYYANEAEHTLPQDTKAVGAIVAISPW
                     NFPLAIFTGEVVSALAAGNTVIAKPAEQTSLIAGYAVSLMHEAGIPTSALQLVLGAGD
                     VGAALTNDARIGGVIFTGSTEVARLINKALAKRNDNPVLIAETGGQNAMIVDSTALAE
                     QVCADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAMDELVVGKPIQLTTDVG
                     PVIDAEAQQNLLNHINKMKGVAKSYHEVKTAADVDSKKSTFVRPILFELNNLNELQRE
                     VFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIRSRIEAGNVYVNR
                     NIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIGQADEAALKRL
                     EALVHKLPFNAEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHAPKRVWIHG
                     GSTVQAFAALTELAASGVQAVVEPDSPLASYTADLEGLLLVNGKPETVGISHVAALSP
                     LDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVAD"
BASE COUNT         6247 a         7656 c         6553 g         6013 t
ORIGIN      
        1 gcaaagtgag tgcacaaagc catctgaagg cgatgtgttt gaaccttttg aaagcggcca
       61 acaggctaag tgcgcccgct gccgcctaaa aagcagcccg gatgcctgat tatcgggtgt
      121 ccgtggagga ttaagggggt atttgggtag aattaggagg tatttggggc gaaaatagac
      181 gaaaacctgt gtttgggttt cggctgtcgg gagggaaagg aattttgcaa aggtctcagg
      241 atttcatatc gatggcaata tagttaaaaa taaggctgca cccagcggca aaccctgctt
      301 tcctgcccat tttcaaactc gatttcatat accgaaacac cagaaaaaac aaaatataag
      361 gccgtctgaa accggtttcg tggttttcag acggcatctg tttcgtttat cgcatcatgt
      421 catcatgccg tacactcgat agcggcttcc gccacgtcgt ccgcactgtg cggcagtgcc
      481 aacgtacggg cgttttctgc ccatttgagg catttttcgc ggtttaagcc gccgagaatc
      541 tcggcgagtt tttccgccgt caactgggtt tgcggcaaca gcaatcccgc ctccgcctgc
      601 accataaaac gcgcgttggc ggtttggtga tcgtcaaccg cgtgggggta cggaacgagc
      661 aacgcaccca atcccgccgc cgtcaactcg gcaatcgtca gcgcgccggc acggcaaatc
      721 accaaatcgg catcgcggta ggcggacacc atatcggtaa taaattccac gcattcggct
      781 ttcacgccca gcgcgtcgta atccgcctgc aagctgccca gcttgccccg tcccgattgg
      841 tggtacatct gcggacgcgc attgtcgggc agcaaagcca atgcctgcgg tacggttttg
      901 ttcaaaacgt ccgcgcccaa actgccgccg accaccaaaa ttttcagacg gccttcacgc
      961 ccttggaagc gttcggcagg cgcgggcagc ttggcaatat cggcgcggac gggattgccg
     1021 accaaaccgc cttcgtggct gaacgctttc ggaaaagcgt acaacacccg cttcgcccag
     1081 cgcgacaggt ggcggttgga caaacctgcc acggcgtttt gctcgtgaat cacaatcggc
     1141 acgcctaata gcttcgccgc caaaccgccg gggaaggtaa cgaagccgcc gaagccgatg
     1201 acgcactcga cacggtgttt gcggataatc cgctgcgctt cgcggacggt ttgatacaaa
     1261 gtaaccggca gcatcagttt gcgtttgatg ccgttgccgc gcacgccttt aatcgccagc
     1321 gtttccaagc gtatgccgta ttgcggcacg atacgctctt ccatcgaatc cttgctgccc
     1381 agccaaatca catgatggcc gcgcgcgcgc aatgaatccg ccaccgccag cgcggggaaa
     1441 atatgtccgc ccgttccgcc cgccatcagc ataaaggttt taccgcccat gatttactcc
     1501 acccgataac cgcgcatttt ccggcggttt tcataatcta tacgcaacag cagcatcatg
     1561 ctgatcagca tgaaaaagac tgacgaaccg ccataggaca tcaacggcag cgtcagacct
     1621 ttggtcggca aagcaccgat gttcacaccg atattgaaga aactttggat accgatccaa
     1681 atgccgatac ccgaagcgat ataggcgttg aaagtcaaac ccaaatcgcg cgactgcttg
     1741 ccgatggaaa acgcccgcac caccagccag ccgtaacaga atatcagcac acacataccg
     1801 aagaaaccga attcttcggc gatgatggca aaaataaaat cggtatgcgc ttccggcaga
     1861 aagccgcgtt tgctcaaact cgcacccaaa cccataccga accactctcc gcgcccgatt
     1921 gccatcagag agtgggtaag ctggtagccg gcaccctgag ggtctttcca cgggtccaaa
     1981 aatgccacta cccgctgcac acggtaggga gcggcggtaa tcatcagcac catcccgccc
     2041 aagacgctgc ctaccaggac gaaaaaatat ttccacggca atcctgccaa aaacagcatt
     2101 ccaacggcaa tgacggtaat gacgacaaac gaaccgaaat ccggctgtac cattatcagc
     2161 accaaaccga acgccaccag cataatcggc aggatgatcg cccggaaacg gccgtacatt
     2221 tctaatgttt cacgacgtgc ctgcggattg gtggcggaca tgatcagatt ggccgtcccc
     2281 cgccaaatcg actgccaacc caaactttcc atgctgcgca acacttcttc acggcgcgtg
     2341 aacaggcttg ccaaataaag gatgaccgcc agcttgaaca gctcggtcgg ctggaaattc
     2401 aacggaccca aaggtatcca acgggtcgcg ccattgattt cgcgcccggc aatcaatacg
     2461 actaccagca acaggccgga tagggcaaaa atccacggca caagccgccg ccatgtcctc
     2521 atcctgcaaa gaaaccataa aaaaccgctc gctatcaagc cggcaacgac gaaccccgcc
     2581 tgtctggtca aatagaaaaa ctgatcgccg ccttccttcg atgccaaata cacagaagcc
     2641 gaataaatca tcagcaggct gaacgccgtc atcagcacca ccatccacaa aagcggcgcg
     2701 tcgaatttcc tgccgtcgcg cacaatcggt ctgtcgagca gcagagtgtg gacaccgtcg
     2761 cccactttta ccaatacttc cgaaatcttc aaaaaaacca cctgccagtc tgtttgcacc
     2821 tgccgcaaag ggcaaaaatt tcagacggca gacaatgccg tccgaacata cgatacatcc
     2881 caaatcggta ttctaaatct ttacttgccg cccaacaatg acggcgtttg catttcagac
     2941 ggcatcacaa agccttaaac gcttcgataa acacttccga acggtgcgcg tagcctttaa
     3001 acatatcaaa actcgcacaa gccgggctga gcagcacgat atcgcacgct tcggcttggg
     3061 catatgccgt ctgaacggct tcttccaaag tggcgcagtc ggtcatattc agaccgcagc
     3121 cgtccaaatc gcggcggatt tgcggcgcat caacgccgat caggaacacg ccttttgcct
     3181 tgccggcaag cgcgtcgcgc agaggcgtga agtcctgccc tttgcccatg ccgcctaaaa
     3241 tcacgaagag cggattttgc aaaccggcaa tcgcggcggc ggtcgcgccg acattcgtgc
     3301 ctttgctgtc atcaatgaat accacgccgt ttttcttgcc gattttttcc acgcggtgcg
     3361 gcaggccttg gaaggttttg acgtgttcaa gcaatgcttc gcgcggcaaa ccgacggctt
     3421 cgcacaaagc cacggcagcc atgacgttgg cggcgttgtg caagccttgc aacggaatgt
     3481 ctttcgtggc aatcaaatct tcattgcctt gtttcaggcg gcctgtctca cgttccaacc
     3541 aaaaatcggc ttcgtgttcc aacgaaaacc attttacctc gcgcccggca cgtttcatgg
     3601 cacggcagaa cgcatcgtcc gcattcaaaa cctgcacacc gtcgccacgg aaaatcttgg
     3661 ctttggtatg cgcgtagtcg agcaagtcgt cgtagcggtc gagatggtct tcggaaatat
     3721 tcagtaccgt cgccgccgtc gggctcaggc tttcggtgtt ttccagttgg aagctggaaa
     3781 gctccaacac ccacacgtcc gcctttttgc cttcgcgctg ccattccgcc tccaaaaccg
     3841 gcgtgccgat attgcccgcg ataacggtat ccagcccgca cttgatacag agatagccga
     3901 ccaggctcgt taccgtggtt ttgccgttgc tgccggtaat cgcaattacc ttgtcgcccc
     3961 ggcggttcac aatgtccgcc agcaattcga tgtcgcccaa cacgcgtccg ccgttttgct
     4021 tgaacgcctc aatatccggc tgacgctcgc tgatgccggg gctgagtgcc aaaatatcga
     4081 aaccgttgtc cagcgcatct ttcagacggc ctgtgtaaaa caccagcccg tcaaacatct
     4141 taccgatttg cgacacgcgc tcgggcttca actccgcatc ataagcggcc acctccgcgc
     4201 cgtttttgcg cagataggca atcatggaaa tacccgtacc gccgagtccg gcgacgagga
     4261 tttttttgtt ttcaagcgtc attttggttt tgtcctaaaa caaatcatat tgggcaggtg
     4321 gggggatgtc cgcccctgcc caagccgctt tcagacggca tcgcgggctg ttcaataacc
     4381 tgccttcagg cgttggtaaa tgtcgcagcc gtcttggtct ccgttttgac aagccttacc
     4441 aaaccattct tgagcgagca caaggtcttg gcgcacgccg cgtcctttgt aatacattgc
     4501 gcccaaattg tattgggctg ctgcatttcc ctgtgctgcc gcctgcaagt tttcccgaaa
     4561 atccgatacg tcatccgccc acaccgcttg gttcaagccc aaggcaatca gggcggcggc
     4621 aagccatttg actgtctgtt tcatggtttt acttctgttt tagtataagc cgccgttaac
     4681 gatagggctg ggcggattgt cgccgcaggt ttattgcgcg ttcaaatgcc gtctgaaaga
     4741 tgttcagacg gcataggttc agcggatttt gagggtactc aaaccgatca acaccaagac
     4801 gatggtaata atccaaaagc ggacgacgac ttgggtttct ttccagcctt tttgttcgta
     4861 atggtggtgg atgggcgcca tcaggaagat gcgttttttg gttttcttgt accagccgac
     4921 ttgaagcata acggacacgg cttcgacgac gaacagaccg cccataatca ctaaaacaaa
     4981 ctcttggcgg acgatgacgg caacggtacc gagtgccgcg cccaatgcca gcgcgccgac
     5041 atcgcccata aagacttgcg cgggataggc gttgaaccac aagaaaccga ggcacgcgcc
     5101 gcacatggcg gtacagaata tagcgacttc gttcgcaccg gcgacatagg gaagctggag
     5161 gtattgggaa aattggtagt gtccgctgac gtaggcgaaa atggcgaggc cggcggcaac
     5221 gaggacgacg gggaaggtcg caaggccgtc caagccgtcg gtgaggttga cggcattgga
     5281 tgtgccgacg atggtcaggt aagacaacac caaaaagccg accacgccca gcggcagggc
     5341 gatttgtttg aagaacggga caatcaaaat attgttggcg gaattggcgg caaggtaaaa
     5401 caatgccaaa ccggcgataa cggcaacgct tgactgccac accattttga atttggcgga
     5461 cacgccgttg gggtctttat agacgacttt gcgccagtcg tcgtaaaaac cgagcgcgcc
     5521 ggtggcaagc aagacgccca agagaatcca gatatacggg tttgcccagt tgccccacaa
     5581 cagggtggac acggtaatgg cggtcagaat cagcgaaccg cccatcgtcg gcgtgccgtt
     5641 tttgacgagg tgggtttgcg gaccgtcggt acgcactgcc tgcccgcatt tgagcgcggt
     5701 cagcctgcgt atcgtccacg ggccgaacat cagggaaaac gccaaggcgg tcaacgccgc
     5761 catgacggcg cggaatgtgg tgtattgaaa aatattcaga ccggttaacc agttgctgaa
     5821 atgtgcgagc cataaaaaca tggggcttcc tttttttgtt tttgtcgtta catgggcttg
     5881 cgcccgtttg aggtttgctt gccgtccggc aaggttcgga cagcttttgc aaattaacgt
     5941 gcagggactt tctcaatcac gcaaatcggg taactccccg gatttttgcc gccgcccaag
     6001 tctaaacata aatcttcata aagatacgcc tgcgtccgca ttccggcata aaacgcgccg
     6061 accagcgcgg caatcaacaa taaggcttta aaaaaacgtc gacttttcat tttcacttat
     6121 cctccaatgc ctcgaccact tcttccatct ccataaagcg cgaacctttc accaacacgg
     6181 tggcgcgttc gggcaaatcg tggcgcaaca cttgaatcaa cgggtctttg gcggcgaacc
     6241 acaaaccgtc cgcgccaaat ttttccgccg cttcgacgct gttgtcgccg acaaaataag
     6301 ccgcttcgat gccttggtcg cgagcatacg cgccgacttc ggcgtgcatg gcggcggctt
     6361 cgtcctcacc cagttcgccc atatcgccca tcacgaaaat acgcggcgca ggcatacgcg
     6421 ccaacacgtc aatcgcggct ttcatgctgt cggggttcgc gttgtaagta tcgtcaatca
     6481 gggttgcacc tttgatgccg gatttgacgt tcagacggcc tttgatattg ctgaagcctt
     6541 tcaaaccttc cgccacatcg ttcaaactca aacctgcagc caaagacagc gcggcggcag
     6601 cggcggcgtt gtggacattg tggcggccgg gaacgggcag aaccacggcg gtgcgctcgt
     6661 tgccgcacac caaatcaaat tcgcacgaca acggtttcag cacgatattt tccgcgtgga
     6721 catcgccgct atcgacgccg aaagtgcgcg tattcaaatt aagcgttgcc gttttgaaga
     6781 cagccatatt ggcatcttct tgaggaatca gtgcaatgcc gtctgaacat aaaccttggt
     6841 aaatctcgct tttcgctttg gcaatatcgc ccactccgtc gaaaccgcag ccgacatggg
     6901 cgcgcatggc gttgttgacc aatgcggcat ttggtttggc gatttgcgtt aaaaccgcca
     6961 gttcgccgaa atggttcatg cccatttcaa tcacggcata gcggtgtttt tcgtttaact
     7021 tcaacaaagt cagcggcaat ccgatatggt tgttgaagtt gcctgccgtc gccaacacgg
     7081 catcatcgcc gaaacggcgg cgcaataccg cagccagcat ttccttcacc gtcgtcttgc
     7141 cgcccgaacc ggtaatgccg aacacaaacg gattcacatt atcgcgccac gccttcgcca
     7201 acatttgcaa cgcggtaagc gtgtcatcga ctttcaacgc gccatccatt gcaacgcaat
     7261 cttcgcgcga aaccacaacc gccgccgcac cagcagccaa tacgtcttca acaaaatcat
     7321 gcgcgtcaaa ccgcccgccc gccaatgcga aaaacacatc gcccgcgcgg ctgtcgcggc
     7381 tgtcggttac gatgcgcgac acgagtttgc tttcagacgg catcggaagc ttgagggctt
     7441 ggcagatgaa atttagatcc agtggtttca tatttacttt cgttaatatt cgggcggcgg
     7501 acacatcggt agcggctgat ttttttatcg cctgttttgc tgtggtaaaa cacagattat
     7561 tttcccattc tcattcggca ttttttctgt acgtatcatt ttttagacgt atttttagtc
     7621 gatttgcctt ttcccgcata ccacggcgcg gggtcgtcgg gcagtccgtc gataaaggca
     7681 aggttattgc cttcgccctg cacatcggga acattccccc aaaaatcata gccgtcatcg
     7741 ggcaactcgt cggtttcgat acccgtccaa ctgccgaatc cgcgtaaaaa attaaacgcg
     7801 ctgcgcctca ctttaatcat ttcgcgccgc gtgtcatcgg acgaaatttt aaccagcggc
     7861 acgccgtagc tttgacgctt ccacgcacca tgtgtcaacg ttcgctcgcc gcctttaccg
     7921 acatgcatca aaccgtggtc ggaaaagtaa accaaagacc agctttcttt attttcattc
     7981 aatatcttaa ctgtatcttc taaaaattta tcggtttgcg cgatggtgga aacatagcag
     8041 gatatttttt cagtttgata ctgaaaccgc cgcgcatcct tatccaaacg tgtgcaaaaa
     8101 tcactgtgcg aacccatcag gtgcatcaca atcagccgag gcttcgtgcc tgcatttcct
     8161 atcaaaaccc gtttgaacgc cggcaacaaa aggcggtcgc tcaaccccgc gcttttgcca
     8221 taatcacccc tttgggtaaa ccacggataa tcgctgcgta aggcataggt ggaaatttcg
     8281 ttggcaaaat gccccaacat tccttgatta gacagccacg ccgtccgaaa acccgcctgc
     8341 ttcgccaagc tgacgatgtt attgttcggt tctcccggca gccccaaagt ctgcggcagc
     8401 gaaagattcg tcgcgtgggc ggtcgattgg taaccgttta tcaacagccc tttggtctga
     8461 ctcaaaaaag gcgtatcggg caatgggaaa ccgtaaacat tcatataatc cgaacgcgcg
     8521 ctctcaccga taaccacaac ataattttta tacttgggcg caacatgacg gatatgccat
     8581 gttgacgctt tttttgctgc ttccaaaatg tgggcgcgct tggcggcata ttgtgccggc
     8641 gcggaagcca aatcgtaata caggtcgaaa atattcaaca acaggccggc atcaggttct
     8701 cgcaaatctt tatcgctggc gattttatcc atcaccgcgc aggacaaaat caaagtcaat
     8761 aatatagtca gccatatttt gctgcggcgt ttatagtttt ttacgtcagc aaataccccc
     8821 gatacacaat atttccaaac tgtcaagcca aaaatgaaaa ataatgcctg cacaaaataa
     8881 agcgacccgg gaagattgcc gacaaattca cgcgcctcgg caggattgct ttccaatatc
     8941 gaaccgacta tctgataaga cggcgcacca tacagccagc cgaccggcaa atatagggcg
     9001 gttgtgccga cgtaaatcag taaaacaact gaagaaacgc gcgggaaacc gcgtgccaat
     9061 aataataaaa atacaaccga agccaaagca cccacagcag aataacggta gccgtattca
     9121 tattccaagt gataacctga tgcgatggcc gcgccaaaac aaaaggctaa aagcgcgcaa
     9181 atgcccaatg tattttttaa tgtctgattc atatttttta ttcgggcgga ttgtttcata
     9241 cgatgccgtc cgaacatccc attatttacg agttaacaaa gcctgtccga cgatttcaag
     9301 atcggaaaaa cggtgcttca cgccttgtac atcctgatag ttttcatgcc ctttgccggc
     9361 aatcaggatg atgtcgtttg cggcggcttg ttcaaccgca taacggatgg cggcggcacg
     9421 gtcggcttcg acgcattcgg gcgcgggaac ggcaggcagg atgtcgttga tgatgtcgtg
     9481 cggattttcc aagcgcgggt tgtcgctggt aacgacgact ttatccgcgc cctgtacggc
     9541 tgccgcgccc atcagcgggc gtttgccgcg atcgcggttg ccgccgcaac cgaatacgca
     9601 ccacaaagcc gcaccctgcg gtttgatttc ctgcaaggtg gcgagtgctt tttccaatgc
     9661 gtcgggcgta tgggcataat cgacaacgac caaaggtttg ccgctgttca tgatgcagtc
     9721 catgcgccct gaagcgggac ggatttttgc cagcacatcc aatactttat caagcggata
     9781 gccgttggcg cacagcaagg cgatgcaggc ggcgaggttt tgcgcgttga accgtccgag
     9841 caggcgcgtg cggcatttcc cttcgcccca cggggtttgg aatacggctg ctatgccgtc
     9901 tgaagaggcg gtaaagtcgg taatgcggat gtcggcgtgt tcgctgaagc cgtaactgta
     9961 aacgaccaaa tcgggacagt cttttttcag acgacctacg agttccgcgc cgtattcatc
    10021 atctacattg ataacggcgt gttgcaggcc gtgccagtaa aacaggcgcg acttgatagc
    10081 gccgtaggct tccatcgtgc cgtggtagtc aaggtggtcg cgtgtgagat tggtaaagat
    10141 tgcgctgcaa aacggcacac cgttgacgcg cgactggtca agcccgtggc tggaaacttc
    10201 catcgcggcg gcggttgcgc cctgttggcg gaaacggtag agcagggttt ggacatcgac
    10261 gggcgcgggg gtggtgtgcg tggtttcttc caatgcgccc caaaagccgt tgccgactgt
    10321 gccgataatg gcggtttttt cgcccaataa atcggcagcc tgcgccagcc attgtgtgat
    10381 ggaggttttg ccgttggttc cggttacgcc ccagactttg aggccgtctg aaacgttgcc
    10441 gtaaacctgt gccgccaaga taccggcacg gtgtttcaaa tctctgatgc cttgattggg
    10501 gactttccat tcgggattcc acgcgaattt gccgtcgtcg tcccaaaaaa caaaagccgc
    10561 gccgttggca acggcggcgg ggatataact gcggccgtcg gcatattcgc ccggacaggc
    10621 aacgaaaata tcgccttgtt tgatttggcg gctgtctgaa tgcaacaaac gccctgccgc
    10681 gtttgcacac ggcaggggcg gaatgccggt ttcagccaaa ggggttaact tgctgaacat
    10741 aaaataatct cgttgatact cggattaaga cggtgttttg acggctgcgg cggtcagggg
    10801 cttggtcggg gaaacgccca agatgttcag gctgccgccc atgacttgct tgaagaccgg
    10861 acctgtcact acgccgccgt agtaaccgtt ggcagtcggt tcgtcgatgg ttaccgccac
    10921 aatcacacgg ggatttttgg caggtgcaaa accgatgaaa gtggcaacgt gtttgtaatc
    10981 gacgtaacgc ccgttgacca acttacgcgc cgtaccggtt tttgcgccga cgtcgaaacc
    11041 atctaccgca cccgccgtac cggtgccgcc cggctcggtc acggaaacca tcagattgcg
    11101 tacctcgcgc gcggtcgatt ctttgaatat gcgtttgcct tgcggcgcaa ccgcctgttt
    11161 ttcaaagctg accggcagca aaacgccgtc gtgcgtcagt gcggtatagg cgcgcgccaa
    11221 ttgcagcagg ctcaattgca ggccgtaacc gaaagacatc gtcgcctgtt cgatgggccg
    11281 ccacctgcgc caatttctca acaaacctgc agtttcgccc ggaaagcccg agtgcatacg
    11341 cacaccgatg cccaactcat gatagaagtc atacatttct tcggcaccga aacgcgcaga
    11401 cagtttgctt gtgccgacgt tggacgattt ctgcatgatg ccgcgcacat ccaaagaggg
    11461 gtaaacatgg gtatcgcgca cgggagacgg tccgatttta taaggctgcg tattcagccg
    11521 ttcgttcaaa tcggttttgc ccgcatccaa tgctttcgca atcacaaacg gtttgattgc
    11581 cgaaccgggt tcgatcatat cggttacggc acggttgcgc cgctgttcgc tgtctgcccg
    11641 gccgggcctg ttgggatcgt aggcgggcgt attggccaag gcgaggattt cccccgtgcg
    11701 ggcatccaaa accaccaccg ttccggcttt tgcctgatgg tattcgaccg ccttgttcaa
    11761 ctcttcatag gccaaggtct gaatcctctg atcgagggaa aggatgatgt ctttgccgtt
    11821 tttcggggct ttattgcgcg gggagtccaa gctgtccaca atattgccct gccggtcccg
    11881 caaaacgact tccgcgccgt cttcgccatg caggctgtct tcaagcgaaa gttccaaacc
    11941 ttcctgacct ttgccgtcaa tatcggtaaa tccgatgacg tgtgcaaaca ggttgcccat
    12001 cgggtaatgg cgttttaatt ctttttcaaa tacaaagttt tccaaaccca aggctttgac
    12061 ctcttcggca accttgggat cgagctgccg cttaatccag ataaacgact tgcctttctg
    12121 ttcgagcttg ttcctcaaaa catcaatcgg aacatcgaca agctcggaca ggcgttccaa
    12181 ttgtgcggca gacggcattt ccttcatctc tttaggcacg gcaaacaggg actccgtcgg
    12241 cgcactcaac gccaaaaccg caccgttccg gtccgaaacc gtaccgcgtg tagccggcaa
    12301 tgtttgagtc cgcacaatcc ggttgtcgcc ctgttctttc aaaaagttat acgttaccgt
    12361 ctgcagatac agtccgcggg caatcagacc ggcaaacaag accgctattg ccatcaggac
    12421 gaagctgatc cgtccgttac tggtcatcgg ctttttgacc tgctcttctt tgggcagcat
    12481 ccggggctta tattcactct taatcaacat ttttacttct cgttattatt atcctgacgc
    12541 aggaatccga ttccggcaca caggctgctt ctatctttga tgcgccacca taaaggtatt
    12601 gcccgaaacc ggcggatgga ggttttgttt ttctgccgcc gccctgatcg cttcgtggtt
    12661 cgccaaacgc gcctgttgca gcctcatttg cgcataatcc tgctccaagg cgatttcctg
    12721 ttttttcgcc ttatccaaag ctgtgaagtt gagcctgtac tggttttgct gcatcacaac
    12781 ggaaaaagcg gaaacgcaca ccgcaagcag cagaaggaaa ttcaatttgt tcattgccat
    12841 tcagacgttt ttctctgtga ttgttccggt atcggaccgg cagtccgctc cgccacacgc
    12901 aaaaccgcac ttctcgccct cggattggcg gcaatttccg cctcacccgg ctttaatgcc
    12961 ctgcccgcga ttttcagggg cggctcgggc aaatccgctt ccctgaccgc cgcccagcgc
    13021 ggcaggggcg cgtgttgcga atattttttg acaaactgct tcacaatgcg gtcttccaac
    13081 gaatggaaag caatgaccgc caaacgtccg ccctctttca gacgacacat gacctgcggc
    13141 aatactgccc ctacttcttc aagctcgcgg ttaataaaga tgcggattgc ctggaaggtg
    13201 cgcgtcgcag gatcctgccc ccgctcgcga gtacggacgt tttgtgccac gatctgcgcc
    13261 agcttgcggg ttgtatcgat tggactttcc gcccgttgcg caacaatggc gcgcgcaatc
    13321 tggcggctaa accgctcttc accataattc ttgattacct cgtgcaaatc ctgttccgac
    13381 gcaaccgcta tccactctgc ggcagacata ccgcgcgtcg tatccatacg catatccaaa
    13441 ggggcatcga aacggaagct gaaaccgcgg ctgccgtcat cgatttgcgg ggacgaaatc
    13501 cccaaatcaa acagcgcacc gtccaccttg ccgataccca aaccgtccaa tgccgtctga
    13561 aacgaagcaa aaccgccatg cacgacaccg acccgtttgt ccgaacgcgc cagctcttct
    13621 gccacagcaa tcgcctgcgg atctttgtcg aaaacaatca accgccccgc atcgcccaaa
    13681 cgcgacaaaa tcagccggga atgccctccc ctgccgaacg taccgtccac atagacaccg
    13741 tcttcgcgca cggcaagcgc atccaccgcc tcattcagca agaccgtgat atgccggtaa
    13801 ctttctgctc cactcacaat tgcaaatccg tctgacccaa ctggaaggca agttcgtcag
    13861 gatcgtcatc caaagcctga accatctcag cctcccactg ctcgcgaccc caaagctcca
    13921 aacggttggc acggccgacc aaaacgactt cacggtcgaa atccaccctt ttcctcagtc
    13981 cggcaggaag cagcacccgg ccggcgctgt cccattccaa aatttccgcg ttatgcagca
    14041 aaagattttg aaaccgccgc aaaacagggt tatccgccac ttttaagttt aaaagttgcg
    14101 ccgcaacctt ttcccactcc gcaacagggt acatcaacag cttgtgtttc gactcgagcg
    14161 ttaccactac ggcaggcgta tagaggcgcg acagaatgtc acggaatttg gcaggaacag
    14221 ccaaccgccc cttactgtcg atgcttaatt cgtgtgcgcc gccgaacatg acatgtccca
    14281 agccgaaatc aaaatcacaa gggtaaaaga gacactttgc cccacaattc cccaccaatc
    14341 gacactataa gaaattttaa acactcggtc aaatcagggc atgaaaactc attaacatat
    14401 ctgaaatttt tattcctttt aaaaacaata agataaaaaa tgacgacaac ggcacggcgg
    14461 gtgcggtaca gaataatcga accaataaac aactatatat gattaattta ataatataaa
    14521 cacaatatat agtattaaga taaagccatg acagcacccg caccaacgtg taatatgtcg
    14581 ggaaatccaa taaatttaca caagctaaca cttatcatgc ccctccccct cccctctccc
    14641 gaagcacggc aattctcgct caaactgcaa accctcattg ccgaaaaaat cggcaaacac
    14701 ggcaactgga ttccattttc acgttttatg gaattggttt tatacgctcc gcaatacggc
    14761 tactacaccg gcggcagcca taaaatcggc aataccgggg attttattac cgcaccgacc
    14821 ctcacctctc tgtttgcaca gacactggca cgccaacttc aagaacttct atcccaaacg
    14881 gcgggcaata tctatgaatt cggcgcggga accggacagc ttgccgccga tttgttgggc
    14941 agcatttcgg acggcatcag ccgttactat attattgaaa tatcgccgga gctggcagca
    15001 cgtcagaaaa acctgattca agcacgcgca ccggaagcat ctcaaaaagt tgtccacttg
    15061 accgcacttc ccgaagcgtt tgacggcatc atcatcggca acgaagtact cgatgccatg
    15121 cctgtcgaaa tcgtccgtaa aaatgaaggc ggctcattcg agcatgtcgg cgtttgccta
    15181 gataatgacc gttttaccta ttcggcacga ccgctgcacg acttacagct atctgccttg
    15241 gcttccctct attttcctca aacagattat ccctacacca gcgaactaca tccgcaacaa
    15301 tatgccttta tccgcaccct tgcctcaagg cttgaacgcg gaggtatgat attcatcgac
    15361 tacggttttg atgcagcgca gtattaccac cctcaacgca atcaaggtac tctgatcgga
    15421 cactaccgac atcacgttat ccacaatcct tttgacttca tcgggttggc cgacctgacc
    15481 gcgcatgtca actttaccga cattgcccaa gccgggacgg atgccggatt agatttgata
    15541 ggttaccttc cccaatccca tttcttattg aacctgggca ttaccgagct attggcacag
    15601 acggggaaaa cggattcggc agcctatatc cgtgaagctg ctgccgttca gaaactgatt
    15661 gaccagcatg aaatgggcga actgtttaaa gtcatcgcat tcggaaaaaa tatcggcatc
    15721 gactgggcag gattccgctt cggcgacatc tgccacaaac tctaaccctc atgccgtctt
    15781 aaccattttc agacggcata aaatttttaa tatttaaaaa caggacacta atttaaaatt
    15841 agaaaatacg gcttgtcaaa aaaacaaaaa aacatataat agcgacttca cgaaacggcg
    15901 aattagctca gtcggttaga gcagaggaat cataatcctt gtgtccgggg ttcgagtccc
    15961 tgattcgcca ccagattttt gggggtatag ctcagttggt agagcgcttg catggcatgc
    16021 aagaggtcag cggttcgatc ccgcttacct ccaccagata aaaaagcaca gaccgtaaaa
    16081 aggtatgtgc ttttttatta cctgattacc ggaaaataaa gaacaaacca ctgcattcaa
    16141 aacaggcaat cgactttaaa cctattgccc cgcctgtcct gattttatca gcccgccaaa
    16201 caaacccggt ccgaataatg tcttcaggcc gggtttatgg tttcattccc aacttatcca
    16261 gcccgacaac cacaatatta tgatgacaat gccaaaaaca atgcggtaat aggcaaatgg
    16321 gatatagttt ttcttggaga caaacttcag cagtgctttg accgctacca aaccggaaac
    16381 aaaagcggca ataaagccta tcagaatcaa accgacatca tgcagggtga aaaaccggta
    16441 atgcttcagg acatcataag ccgttgctgc aaccatcatc ggaacggcca agaaaaatga
    16501 aaactccgtt gccgttttcc gctcgattcc ccaaagcatc ccgcccataa tcgtactgcc
    16561 cgaacgggac gtacctggaa ccagtgcaaa cacttgggca acgccgatca tcaacgcatc
    16621 aatcggacgc aatgcatcaa catcgacaat tttaggctct gctcggcttt ggcgtttctc
    16681 cacccacaaa ataaaaaaac cgcccaaaac cagcatgact gcaacactca aggggttaaa
    16741 cagatactct ttgatttgtt tgccgaacaa cagccccatc acggcggcag gtataaaagc
    16801 aatggcaaga ttaaggacga aacggttggc tttccggtct tttcccacgc catgcaacac
    16861 attgctgaaa cgctgccggt attcaaacac taccgccaaa accgcaccga gctggatggt
    16921 aatttcaaaa accttgtgat tgctgtgaaa atcaatcaga ttgccgaaca caatcaaatg
    16981 tccggtgctg gaaatcggta aaaattcggt aaaaccttct accaagccca tcatcagggc
    17041 tttcaggaca atcagaaaat ccattgcttg cgcttctttc ggatacggga gttcggctat
    17101 ttctgtacag caggggtctg acgcttgcgt tcttccctga ctttggcaac caattcttta
    17161 atcgtatgaa caccgccgtc aaagccatta ttgaagataa cgcggtattt tccgccgacg
    17221 acaacggtcg gcgtactgtc gatgcggtac tgttccgtca attgctgcat ttttgatgca
    17281 gcagccgctg ccgcaggaga gtcgtaggcg cgcatcagtt ttttgccgtc aaagcctttt
    17341 tgagacaaag cccatttttc ggcaaccgac ctgttttcca agcggatttt ttgttcgtaa
    17401 actgctttaa acacggcagg gtttgcctga tatttcaaac ctgacagctt gaccgcagca
    17461 gccattcttg ccagaccgag catttcaggc tgccagacca cgtgctccgt ccttaaatag
    17521 gcatcagacg gcaatgcctt gcccaatttc aataacaaag gatcgaaatg atggcaatgt
    17581 acgcagaaat agccgaaaaa ttccaaaacc tcaattttgc ccgactgttt ttgaggaatg
    17641 ggtttatcca acacaagata gtcttcccct tccgtcaggg catatgcctg cgcggacaac
    17701 actgccgaca gcagcagcgg caacagatgt ttgagcttca taattatttg ctttcgatag
    17761 aacggatcag gctggcgact tcatgttttt tcaactcgtc ctgcattttt ttcaccgcat
    17821 cggcagacat attgccgctt tgcacccggt aaagcgtttt atgtcccgcc tgataaccga
    17881 ccaccttgga agatatgccc aagattgcca gtttggcacg ctgcccttcc gcgctccggc
    17941 ggtcggcata cgcgcccatt tgcagataat gcgttgcttc cgccttgtcg ggcgttttca
    18001 ttttctgcac ttctttggca gcggcactgc gcgctttttc gatgctgccg ctgttgagga
    18061 tttgttccgg ggtcggtttg ggtgcaactt tttccttctc cgcctttttc tcttcttttg
    18121 aagctttttt ctctgtttct ttagatggtt ttaccgcttg ttttttaacc gtttcggcat
    18181 ctttcttctg cgctttttcc ccgacggttt gttcacgctc ttccgtcagt gctttcttgc
    18241 gcactgcctg tccgtccgac ttttcccgct ccggctcgtc cgccttttcc tcaacctcgt
    18301 cggctttgtc ggcaacgggc tgcttgtcgg cagctttttc cgcatccgac tgctctgcct
    18361 ctttcgcagc atccggttcg gacaaggcgt tttgatcggc cggttcaggt tggatgtctt
    18421 ccttaggctg gtttttcggt ttcaggattt ccgtttctgc aggctgcttc gacggaaccg
    18481 ggattttgaa cgcattttga ccgctctggt tcagataaaa caaaataccg gcaataatga
    18541 ccgtcgccag tatcaaaccg aagaaaaaac cggacagacc ttttccggat tgggaaaatt
    18601 tgttcataaa cataccttaa tgtgtttcag acggcattaa cgccgtttgc ttacgggcgg
    18661 atattctaac aatatcgcca tatttgggca aaacctgctt ccattcccat tcctataaag
    18721 cgcgacggaa acctatggct ttcatgacgt ggcttctgcc gacttcttcg tcgcccgcca
    18781 aatccgccaa tgtacgcgcc acgcgcataa tgcggtggaa gctgcgggcg gaaagggaga
    18841 gtttttccat caggccgccc aatgcttcct gcgcttcttt ttgaatgcgg gcttgggaat
    18901 cgagttcgct gacgctcaaa gcggcgttga ctttgccctg ccgtgcgtat tgtttgtcgc
    18961 gggcggcgat aacgcgttcc aaaacggacg cgctgctttc gcccgcttcc tgctgcatca
    19021 gttcggcggc ggacaggctg gggacttcga tggtcaaatc gatgcggtcg agcagcggcc
    19081 cggaaatctt gctgcggtaa cgcgcgacgc tttcgggcgt gcagcggcag ggtttgacgg
    19141 gatgcccgag ataaccgcac gggcaggggt tcatggcggc aacaagttgg aatttggcag
    19201 gatagacggc ttggcgcgcc gcgcgggaaa tgtggatttc gccgttttcc aacggttcgc
    19261 gcaaaacttc caaaactttg cggtcaaact cgggcagctc gtccaaaaac aaaacgccgt
    19321 ggtgcgccaa tgaaatttcg cccggacgcg gatccgaacc gccgccgacc atagccgccg
    19381 cgctggcgct gtgatgcgga ctgcggaaag gacggttgct gtcgagttgt tgttggtggt
    19441 tgggcaggag cgaacgcaat gcccaaactt ctaccaattc gtcttcggtc agcggcggca
    19501 ggatgccggg cagccgttgg gagagcatag acttgcccgt tcccggcgga cccatcatca
    19561 agaggctgtg tccgcctgcg gcagcgattt ccaaagcaag gcgcgcggtg tgctgacctt
    19621 tcacatcgca caaatcaggt tgtccgccat gttcaaacgg catctgagga acttggcatt
    19681 cggtttgcgc caaaggttcg atgccgttca aatgggcggc gacttcgccc aaagagcgcg
    19741 cgccgtaaac ggtaatgccg cgcatcacgg cggcttgtcc tgcattttct tcaggcaaaa
    19801 caaatgcacg ttttgcctgc ataccctgcc acgccatcgc caacgcgcca cgcacggggc
    19861 gcaacagccc cgacagtgcc aattcccccg caaactcgta ttccgccagt ttttcgggcg
    19921 caacctgccc cgatgcggca aggatgccga ttgcaatcgg caaatcgaaa cgccccgact
    19981 ctttgggcag gtcggcgggg gcgaggttga cggtaatttt tttggcgggg aattcaaaac
    20041 cgctttgaat aatggcggca cggacgcggt cgcggctttc ctttacttcc gtatcgggca
    20101 gcccgacgat gttgaaatgc ggcaggccgt tggcaaggtg ggcttccact tcgaccaacg
    20161 gcgcattcat accgctcaag gcgcggctgt aaaccaaggc aagcgacata tttcagacgg
    20221 ccttattcgc cggcttcggt ttgctgcctg atttcggcga cggcttcttc ggcagcggct
    20281 tcagccgctt ccaatgctgc ccgttcggga ttttgcgcgg cttcgagttt tgccaaacgc
    20341 gcttccaaag ccgccagttt ggtacgagtt ttgattaaaa cctgctgctg gatgtcgaat
    20401 tcttcgcgcg taaccagatc catacggttg aacgcgccgc ccagcatcga cttaatattt
    20461 ttttccacat ctttggcagg gctgttggcg atggtttcgc tgattttcga accgacttct
    20521 tcaaaaagct gcttgccgaa cataatctgt atccttcctg aacatatcaa attcaatcgg
    20581 ctattgtata aggaaaaatg ccgtctgaaa acgggcggcg gataatcggc aaaacatacc
    20641 gcgcctcctt tgcggttgct aaattacacc tcaaaacacc tgccgcctga aaacggattt
    20701 catattccgc gcaacgccag attacaagac actacaaaac aatatactgt tttaaatgat
    20761 ttttccgacg cgcatcgttt caaactcggc tttttaagcc attaagtgct ttgcaaacaa
    20821 cagaaattgg gttatcctga aacggattat ttacaatttc atatagtttt attacatatc
    20881 ttattgtgat tgaagataat ttatccgaat ccccctttcg ggtatccgga ttttccgttg
    20941 tacttttatt agaaaaacat ttcaggcgca agttgcttgc aatttcaaag cctgtaattc
    21001 tgaagtttta gacgaggaat agcacatgaa tcccatgtac attacttttg caatctatct
    21061 ggttgcagtc cttctcatcg ggcttgccgc ctatttttcc acgcgcaatt tcgacgatta
    21121 tattttgggc gggcgcagcc taggcccgtt tgttaccgcg atgtcggcag gcgcgtccga
    21181 tatgtccggc tggctgctga tgggtctgcc gggcgcgatt tacctgagcg gtttgaatga
    21241 ggcttggatt gccatcggcc tcttggtcgg cgcgtatttc aactggctct tggtggcggg
    21301 ccgcctgcgc gtgcataccg aatacgccaa caatgcgctg acgctgccgg attatttctt
    21361 ccaccgcttc ggcgcgggcg gacacttgat gaaagtggtt tccgcactga ttatcctgtt
    21421 cttcttcacg atttattgcg cctcgggcat tgtggcgggc gcaaccctgt tccaaagcct
    21481 gtttgaaggt atgacttaca atcaggcaat gtggctgggc gcgggcgcga ccatcgccta
    21541 taccttcttg ggcggtttct tggcggtcag ctggacggat acgctgcagg cttctttgat
    21601 gattttcgcc ctgattttaa cgccggtgat ggtctatctg ggcttgggcg gcgcggaaca
    21661 gatgtctgcc gcgattcaaa gcgtcgccgc aggcacgggc aaagaatacg gcagcctgtt
    21721 tgccggtacg accgtcatcg gcatcatttc caccgccgca tggggcttgg gctatttcgg
    21781 acagccgcac attttggcgc gctttatggc ggccgaaagc gcgaaatcgc tggtatccgc
    21841 acgccgcatc ggcatgactt ggatggcgtt gtgccttgcg ggcgcggtgg cggtcggtta
    21901 tttcggcatt gcgtatttcg gtgcaaatcc cgacaaagtt tcttctatga gcggcaacca
    21961 cgaacgcatc ttcatcgcgc tttccaccct gctgttcaac ccttggatcg ccggcatcat
    22021 tttgagcgcg attttggcgg cggtgatgtc caccctgtcc tgccagcttt tggtttgctc
    22081 cagcgcgatt accgaagact tctacaaagg ctttttgcgt aaaaatgcgc aacagtcgga
    22141 attggtatgg gtcggccgcc tgatggtctt ggcgattgcc gtgatttcca tcctgattgc
    22201 ttccgatccg aacagcaaag tattgggact ggtttcttat gcgtgggcag gtttcggtgc
    22261 ggcgttcggc ccgattgtga ttctgtccgt attgtggaaa cgcatcactg cctacggcgc
    22321 gttgtcgggt atggttgcag gtgccttaac cgtagtcgta tgggcggaat gggtgaaaaa
    22381 accggctcaa gcggcaggag aaagcggctt gttgacgatg tacgaaatcg tcccgggctt
    22441 tattgtttgc ttaatcattg ccgtgttggt ttccctgttc aacaaagaac cttcgcgcga
    22501 aatccaagaa cgctttgaaa aagccgacgc agattaccgc gccgcccgat aaaccccttt
    22561 cagacggcac ggcatcccgg ttcgtgccgt ctgaacccgt ttccgggtca aacacaaata
    22621 aaccttgcct gcatacaggc cttatttgtg ttttacccgt ttcattttca aagaaacgga
    22681 agcacctacc ctgcccgcat ttgaagcctt gtatttcatc tgcggattta ttacgatatt
    22741 accgtattca ggccgcaccg atgccgcctg ccccccgaaa aactttggag aatccaaaaa
    22801 atgtttcatt ttgcatttcc ggcacaaact gccctgcgcc aagcgataac cgatgcctac
    22861 cgccgtaatg aaatcgaagc cgtacaggat atgttgcaac gtgcacagat gagcgacgaa
    22921 gagcgcaacg ccgcctccga gcttgcccgc cgtttggtta cccaagtccg cgccggccgc
    22981 accaaagccg gcggcgtgga tgcgctgatg cacgagtttt cactctccag cgaagaaggc
    23041 atcgcgctga tgtgtctggc agaagccctg ctgcgtatcc ccgacaacgc cacgcgcgac
    23101 cgcctgattg ccgacaagat ttcagacggc aactggaaaa gccatttgaa caacagccct
    23161 tccctcttcg tcaatgctgc cgcctggggc ctgctgatta ccggcaaact gaccgccaca
    23221 aacgacaaac aaatgagttc cgcactcagc cgcctgatca gcaaaggcgg cgcaccgctc
    23281 atccgccaag gcgtaaatta cgccatgcgg cttctgggca aacagttcgt aaccggacag
    23341 accattgaag aagccctgca aaacggcaaa gaacgcgaaa aaatgggcta ccgcttctcc
    23401 ttcgatatgt tgggcgaagc cgcctacacc caagccgatg ccgaccgcta ctaccgcgac
    23461 tatgtcgaag ccatccacgc catcggcaaa gatgcggcag gacaaggcgt ttacgaaggc
    23521 aacggcattt ccgtcaaact ctccgccata catccgcgct actcgcgcgc ccaacacggc
    23581 cgtgtgatgg gcgaactgtt gccgcgcctg aaagagctgt tccttttggg taaaaaatac
    23641 gatatcggta tcaacatcga tgccgaagaa gccaaccgtc tggagctgtc tttggatttg
    23701 atggaggcac tcgtttccga tcccgatttg gcaggctaca aaggcatcgg tttcgttgtt
    23761 caagcctacc aaaaacgttg tccgttcgtt atcgactacc tgatcgacct tgcccgccgc
    23821 aacaaccaaa aactaatgat ccgcctcgtc aaaggcgcgt attgggacag cgaaatcaaa
    23881 tgggcgcaag tggacggctt gaacggctat ccgacctaca cccgcaaagt ccacaccgac
    23941 atctcctacc tcgcctgcgc gcgcaaactg ctttccgcgc aagacgcggt atttccgcaa
    24001 ttcgccaccc acaacgccta caccttgggc gcaatctacc aaatgggcaa aggcaaagac
    24061 tttgaacacc aatgtctgca cggcatgggc gaaaccctgt acgaccaagt cgtcggcccg
    24121 caaaacttag gccgccgcgt gcgcgtgtac gccccggtcg gcacacacga aaccctgctc
    24181 gcctacttgg tgcgccgcct gttggaaaac ggcgcgaact cgtctttcgt caaccaaatc
    24241 gtcgatgaaa acatcagcat cgacacgctc atccgcagcc cgttcgacac catcgccgaa
    24301 caaggcatcc acctgcacaa cgccctgccg ctgccgcgcg atttgtacgg caaatgccgt
    24361 ctgaactcgc aaggcgtgga cttgagcaac gaaaacgtat tgcagcagct tcaagaacag
    24421 atgaacaaag ccgccgcgca agacttccac gccgcatcca tcgtcaacgg caaagcccgc
    24481 gatgtcggcg aagcgcaacc gattaaaaac cctgccgacc acgacgacat cgtcggcaca
    24541 gtcagctttg ccgatgccgc gcttgcccaa gaagcggttg gcgcagccgt tgccgcgttc
    24601 cccgaatgga gtgcgacacc tgccgccgaa cgcgccgcct gcctgcgccg tttcgccgac
    24661 ctgctcgaac agcacacccc cgcgctgatg atgcttgccg tgcgcgaagc aggcaaaacg
    24721 ctgaacaacg ccattgccga agtgcgcgaa gccgtcgatt tctgccgcta ctacgcaaac
    24781 gaagccgaac acaccctgcc tcaagacaca aaagccgtcg gcgcgattgt cgccatcagc
    24841 ccgtggaact tcccgctcgc catctttacc ggcgaagtcg tgtccgcatt ggcggcaggc
    24901 aacaccgtta tcgccaaacc cgccgaacaa accagcctga ttgccggtta tgccgtttcc
    24961 ctcatgcacg aagccggcat cccgacttcc gccctgcaac tcgtcctcgg cgcaggcgac
    25021 gtgggtgcgg cattgaccaa cgatgcccgc atcggcggcg taattttcac cggctcgacc
    25081 gaagtggcgc gcctgatcaa caaagccctt gccaaacgca acgacaatcc cgtcctgatt
    25141 gccgaaaccg gcggacaaaa cgccatgatt gtcgattcca ccgcacttgc cgaacaagtc
    25201 tgcgccgacg tattgaactc cgccttcgac agcgcgggac aacgctgctc cgccctgcgt
    25261 atcttgtgcg tccaagaaga cgttgccgac cgtatgctcg acatgatcaa aggcgcgatg
    25321 gacgaactcg tcgtcggcaa accgattcaa ctcaccaccg atgtcggccc cgtcatcgat
    25381 gccgaagcgc agcaaaacct gttgaaccac atcaacaaaa tgaaaggtgt tgccaagtcc
    25441 taccacgaag tcaaaaccgc cgccgatgtc gattccaaaa aatccacgtt cgtccgcccc
    25501 atcctgtttg aattgaacaa cctcaacgaa ctgcaacgcg aagtcttcgg ccccgtcctg
    25561 cacgtcgtcc gctaccgcgc cgacgaactc gacaacgtca tcgaccaaat caacagcaaa
    25621 ggctacgccc tgacccacgg cgtacacagc cgcatcgaag gcacggtacg ccacatccgc
    25681 agccgcatcg aagccggcaa cgtttacgtc aaccgcaaca tcgtcggcgc agtcgtcggc
    25741 gtacagccct tcggcggaca cggtctgtcc ggcacaggcc ccaaagcagg cggttcgttc
    25801 tacctgcaaa aactgacccg cgccggcgaa tgggttgccc cgaccctgag ccaaatcgga
    25861 caggcggacg aagccgcact caaacgcctc gaagcactgg ttcacaaact gccgttcaac
    25921 gccgaagaga aaaaagccgc agcggccgct ttgggacacg cccgcatccg caccctgcgc
    25981 cgtgccgaaa ccgtccttac cggaccgacc ggcgagcgca acagcatctc atggcacgcg
    26041 ccaaaacgag tttggataca cggcggcagc acggttcaag cctttgccgc actgaccgaa
    26101 cttgccgcct ccggcgtaca ggcagtggtc gaacccgaca gcccgctggc ttcctacacc
    26161 gccgacttgg aaggtctgct gctggtcaac ggcaaacccg aaaccgtcgg catcagccac
    26221 gttgccgccc tgtcgccttt ggacagcgcg cgcaaacagg aacttgccgc ccacgacggc
    26281 gcactcatcc gcgtcctccc ttcggaaaac ggactcgaca tcctgcaagt ttttgaagaa
    26341 atctcttgca gcgtcaacac cacagccgcc ggcggcaacg ccagcctgat ggcggttgcc
    26401 gactgatttt accgaaatcc ccgagcgcgg cccgtgaacc aatgccgtct gaaaaccttt
    26461 cagacggca
//
LOCUS       DAXIDM010000015        25897 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000015 DAXIDM010000000
VERSION     DAXIDM010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 25897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25897
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.015"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(125..217)
                     /locus_tag="ACFOAE_000531"
     tRNA            complement(125..217)
                     /locus_tag="ACFOAE_000531"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(181..183),aa:Ser,seq:gct)
     gene            complement(374..574)
                     /locus_tag="ACFOAE_000532"
                     /pseudo
     CDS             complement(374..574)
                     /locus_tag="ACFOAE_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237659.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
     gene            complement(676..993)
                     /locus_tag="ACFOAE_000533"
                     /pseudo
     CDS             complement(676..993)
                     /locus_tag="ACFOAE_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237659.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
     gene            complement(1016..1777)
                     /gene="kdsB"
                     /locus_tag="ACFOAE_000534"
     CDS             complement(1016..1777)
                     /gene="kdsB"
                     /locus_tag="ACFOAE_000534"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008690 - 3-deoxy-manno-octulosonate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HFC6884081.1"
                     /translation="MTEFVVLIPARLDSSRLPGKALADIHGKPMVVRVAEQAAKSKAV
                     RVVVATDHPDIQTACQAHGVEVVMTSNRHESGTTRLAEASAALKLPPHLVVVNVQGDE
                     PLIAPELIDRTAEVLVENNVQMATAAHELHDFDELMNPNAVKVVLDKNRNAIYFSRAP
                     IPYPRDAMRAGKREMPSETAVLRHIGIYAYRAGFLQRYAEMSVSPLETIESLEQLRVL
                     WHGYPIAVETAKEAPAAGVDTQEDLDRVRAVFQTV"
     gene            complement(1774..1956)
                     /locus_tag="ACFOAE_000535"
     CDS             complement(1774..1956)
                     /locus_tag="ACFOAE_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trm112 family protein"
                     /protein_id="HFC6884082.1"
                     /translation="MEKKFLDILVCPVTKGRLEYHQDKQELWSRQAKLAYPIKDGIPY
                     MLENEARPLGEEELEA"
     gene            complement(2025..2606)
                     /locus_tag="ACFOAE_000536"
     CDS             complement(2025..2606)
                     /locus_tag="ACFOAE_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2059 domain-containing protein"
                     /protein_id="HFC6884083.1"
                     /translation="MKLKTLLLPFATLALCTNAFAAPPSDASLARWLDTQNFDRDIEK
                     NMIEGFNAGFKPYADKALAEMPEAKKDQAAKAFNRYRENVLKDLITPEVKQAVRNTLL
                     KNAREIYTQEEIDGMIAFYGSPVGQSVVAKNPRLIKKSMSEIAVSWTALSGKIARHHL
                     PAFTEELRRIICGGKNPDAGCKQAGQVGKRHQK"
     gene            complement(2813..3847)
                     /gene="lpxK"
                     /locus_tag="ACFOAE_000537"
     CDS             complement(2813..3847)
                     /gene="lpxK"
                     /locus_tag="ACFOAE_000537"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_025462052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009029 - tetraacyldisaccharide 4'-kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HFC6884084.1"
                     /translation="MPNCFKFHTVIERHWQKPYPVLSFLLKPLSGLFAKIAAKRRTDF
                     LSGKRQSEKLPVPVVVVGNIHAGGTGKTPIVAALVSGLQEKGVKVGIISRGYGRKSKA
                     VHVLNAESRAEDAGDEPLLLFRKTGAPTAVGSSRAEAGRALLAAHPDIGLIVADDGLQ
                     HYALRRDVEIAVFPAADTGRTDLDLLPNGSLREPLLRLDSVDAVVVSGGKADALFRPS
                     ENMFHSRIEAGRIYRLNNPSEILDTGRLKNQTVVAVAGIAKPARFFDSLRNMGITVKR
                     TVALPDHADISAADLPDADAVIITEKDAVKFSDGICTDNVWVLPVCAIIEPDLAAFVL
                     ERLEDVPKAV"
     gene            complement(3955..4158)
                     /locus_tag="ACFOAE_000538"
     CDS             complement(3955..4158)
                     /locus_tag="ACFOAE_000538"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884085.1"
                     /translation="MKEMKPVRYHIGDMPETSKQTASRHDDRAVGVDDDCFHDSFGQF
                     LFGCSAEATRTAPISVKRSCLFT"
     gene            complement(4394..5674)
                     /locus_tag="ACFOAE_000539"
     CDS             complement(4394..5674)
                     /locus_tag="ACFOAE_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malic enzyme-like NAD(P)-binding protein"
                     /protein_id="HFC6884086.1"
                     /translation="MENSLKEAALKFHELPVPGKISVTPTKSLATDKDLALAYSPGVA
                     APCMEIHADPQNAYKYTAKGNLVAVISNGTAVLGLGDIGALAGKPVMEGKGVLFKKFA
                     GVDVFDIEIDEKDPQKLVDIIAALEPTFGGINLEDIKAPECFYIERELRKRCKIPVFH
                     DDQHGTAIITAAAVLNALRFTGRKIEEATLVCSGAGAAAIACLNQLLDLGLKRENVTV
                     CDSKGVIYQTREDKDRMDESKQFYAIEDNGQRVLADAVKGKDIFLGLSGANLLTPEML
                     NTMNEKPIVFAMANPNPEILPPLAKETRPDVVIGTGRSDFPNQVNNVLCFPFIFRGAL
                     DVGATTINEEMKRACVYALADLAMEEVTEEVVAAYGKKFEFGAEYLIPTPFDSRLLPR
                     VATAAAKAAMESGVATRPIADLEAYAAKLSEWKL"
     gene            complement(5896..6516)
                     /gene="tmk"
                     /locus_tag="ACFOAE_000540"
     CDS             complement(5896..6516)
                     /gene="tmk"
                     /locus_tag="ACFOAE_000540"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFC6884087.1"
                     /translation="MKPQFITLDGIDGAGKSTNLAVIKAWFERRGLPVLFTREPGGTP
                     VGEALREILLNPETKAGLRAETLMMFAARMQHIEDVILPALSDGIHVVSDRFTDATFA
                     YQGGGRGMPSEDIEILEHWVQGGLRPDLTLLLDVPLEVSMARIGQTREKDRFEQEQAD
                     FFMRVRSVYLNRAAACPERYAVIDSNLGLDEVRNSIEKVLDRHFGC"
     gene            complement(6576..7571)
                     /gene="mltG"
                     /locus_tag="ACFOAE_000541"
     CDS             complement(6576..7571)
                     /gene="mltG"
                     /locus_tag="ACFOAE_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFC6884088.1"
                     /translation="MLRKLLKWSAVFLTVSAAVFAALLFVPKDNGRAYRIKIAKNQGI
                     SSVGRKLAEDRIVFSRHVLTAAAYVLGVHNRLHTGTYRLPSEVSAWDILQKMRGGRPD
                     SVTVQIIEGSRFSHMRKVIDATPDIEHDTKGWSNEKLMAEVAPDAFSGNPEGQFFPDS
                     YEIDAGGSDLQIYQTAYKAMQRRLNEVWAGRQDGLPYKNPYEMLIMASLIEKETGHEA
                     DRDHVASVFVNRLKIGMRLQTDPSVIYGMGAAYKGKIRKADLRRDTPYNTYTRGGLPP
                     TPIALPGKAALDAAAHPSGEKYLYFVSKMDGTGLSQFSHDLTEHNAAVRKYILKK"
     gene            7655..8227
                     /gene="ampD"
                     /locus_tag="ACFOAE_000542"
     CDS             7655..8227
                     /gene="ampD"
                     /locus_tag="ACFOAE_000542"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HFC6884089.1"
                     /translation="MDNHAEAHWQNGWLQSIRHTPSPNFSPRETGETVSLIVLHNISL
                     PPFEYGTDAVEKLFANRLDPDGHPFFSLIHTLRVSSHFLIKRDGETVQFVSCDNMAYH
                     AGVSSFRGREKCNAFSIGIELEGCDFEPFTEAQYRSLEALLDAICRRYPITAVTGHQD
                     IAPGRKTDPGHFFDWRRIRGKGFPVDRNAV"
     gene            8421..9707
                     /locus_tag="ACFOAE_000543"
     CDS             8421..9707
                     /locus_tag="ACFOAE_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0090529 - cell septum assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA C-terminal
                     FtsZ-binding domain-containing protein"
                     /protein_id="HFC6884090.1"
                     /translation="MIYIVLFLAAVLAVVAYNMYQENQYRKKVRDQFGHSDKDALLNS
                     KTSHVRDGKPSGGSVMMPKPQPAVKKTAKLQDPAMRNLQEQDAVYIAKQKQAKASPFK
                     TEIETALEESGIIGNSAHTVSEPQTGHSAPKPADAPAKPAPVPQTPAKPLITLKELSK
                     VELPWFDVRFDFISYIALTEAKELHALPRLSNRCRYQIVGCTMDDHFQIAEPIPGIRY
                     QAFIVGIQAVSRNGLASQEELSAFNRQVDAFAQSMGGQTLHTDLAAFIEVASALDAFC
                     ARVDQTIAIHLVSPTSISGVELRSAVTGVGFVLEDDGAFHYTDTSGSTMFSICSLNNE
                     PFTNALLDNQSYKGFSMLLDIPHSPAGEKTFDDLFMDLAVRLSGQLNLNLVNDKMEEV
                     STQWLKDVRTYVLARQSEMLKVGIEPGGKTALRLFS"
     gene            9855..12380
                     /gene="ligA"
                     /locus_tag="ACFOAE_000544"
     CDS             9855..12380
                     /gene="ligA"
                     /locus_tag="ACFOAE_000544"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFC6884091.1"
                     /translation="MNPNSKHNTNFTNLLKPSDSDIKQFAAQHICRLTDLLNRYAYEY
                     YTLDAPSVPDAEYDKLFRELEALELNHPELKLPDSPTQRVGGEPLAGFAEVRHEVPML
                     SLTNAFSPQDENGVFDHAEMYAFDQRVRDGLDGGNPEYVIEPKFDGLAISLLYRDGVL
                     VQAATRGDGTTGEDVTQNIKTVSNIPLRLHGENTPELIEVRGEVLMQKADFAALNKRQ
                     AENGQKPFANPRNAAAGSLRQLDSRITAQRKLHFFPYSVARRQGGFVAEEHIQELAYF
                     QALGFSLPNGNFGCFKNIDEVLAFYEHMQQKRPELPYEIDGMVVKVNSLAQQRELGFI
                     SRAPRWAIAHKFPAEEALTVVEAIDVQIGRTGAVTPVARLQPVFVGGVTVTNATLHNQ
                     DEVSRKDVRVGDTVVVRRAGDVIPEVVRVIFERRPMQETAVAVSDGIGHRQDDLFAEA
                     PAANQTQSVPLYKPYRLPTHCPICRSEIEREEGEAVARCSGGMLCQAQRAQGLIHFAS
                     RKAMDIDGLGEKQIEQLVAQDLVRHFADLYRLDIPTLQKMKETADKTVAESDQMPSEG
                     SSVGASGKHKKQPTKWAENILAGIESGKTPELARFLFALGIRHVGERTAKTLAQAFGT
                     LERVRRAPEPVLACLPDIGTVVARSIAHFFAQAEQQAMIDELLAAGVAPQAQAVSLPA
                     AQYAEPQRWIARLPGFKISENKAQALWELAGKSIEGLQTDKSLPADWQAWRSEPQNAA
                     LLENLKTFFAQMPSEDEAAQGSDGINKAVAGKTFVLTGTLPTLKRDQAQSLIEAAGGK
                     VSGSVSKKTDYVVAGEAAGSKLEKANALGVSVLSEAELLTLLG"
     gene            12437..13612
                     /gene="hemW"
                     /locus_tag="ACFOAE_000545"
     CDS             12437..13612
                     /gene="hemW"
                     /locus_tag="ACFOAE_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFC6884092.1"
                     /translation="MHTISFPNRTRLTALPPLSLYIHIPWCIKKCPYCDFNSHSLKNG
                     LPEAAYIDALLTDLQLELPNIWGRPVETIFFGGGTPSLFQAESIDRLLSGVRSLLRLQ
                     PEAEITLEANPGTFEIEKFQGFKDAGITRLSIGVQSFNDDMLSRLGRVHNGKEALTAI
                     DTALKLFDKVNIDLMYALPNQTVQTALDDVQTAIATGATHISAYHLTMEPNTPFGHTP
                     PKGLPQDEAALDIEDAVHGALESAGFVHYETSAFAKPAMQCRHNLNYWQFGDYLGIGA
                     GAHGKISYPDRIERTVRRRHPNDYLALMQSQPSEAVERKTVAAEDLPFEFMMNALRLT
                     DGVPAAMLQERTGVPSAKIMAQIETARQKGLLETDPAVFRPTEKGRLFLNDLLQCFL"
     gene            14197..14721
                     /gene="nspA"
                     /locus_tag="ACFOAE_000546"
     CDS             14197..14721
                     /gene="nspA"
                     /locus_tag="ACFOAE_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane beta-barrel protein NspA"
                     /protein_id="HFC6884093.1"
                     /translation="MKKALATLIALAIPAAALAEGASGFYVQADAAHAKASSSLGSAK
                     GFSPRISAGYRINDLRFAVDYTRYKNYKAPSTDFKLYSIGASAIYDFDTQSPVKPYLG
                     ARLSLNRASVDLGGSDSFSQTSTGLGVLAGVSYAVTPNVDLDAGYRYNYIGKVNTVKN
                     VRSGELSAGVRVKF"
     gene            14857..15246
                     /locus_tag="ACFOAE_000547"
     CDS             14857..15246
                     /locus_tag="ACFOAE_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFC6884094.1"
                     /translation="MSKTIIHTDKAPAAIGAYSQAVRAGDTVYMSGQIPLDPATMTVV
                     GNGDFRAEARQVFQNLQAVAEAAGGTLADIVKLNAYLTDLGNFAVFNEVMAEFIAEPF
                     PARAAVGVASLPKGVQVEAEAVLVLNA"
     gene            15324..16154
                     /locus_tag="ACFOAE_000548"
     CDS             15324..16154
                     /locus_tag="ACFOAE_000548"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008803 -
                     bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="symmetrical bis(5'-nucleosyl)-tetraphosphatase"
                     /protein_id="HFC6884095.1"
                     /translation="MAHYAIGDIQGCFDELTALLGKIGFNHGTDTLWLTGDIVNRGPK
                     SLETLQFCIRHENSVQIVLGNHDLHLLAVGCGEGAPKRSDTIEPILKHPDGKKMLDWL
                     RAQPLLIREGSRVMVHAGILPQWRIAKAESLAREAEAELRGKKHVKFFSKMYGNKPAA
                     WDESLKGYARLRFIVNAFTRMRALTFKNELDFDYKSTVKKMPPYLRPWFKAPDRQNLD
                     RTIIFGHWSSLGYTNADNVISLDTGALWGGQLTAVNLETEEITQVQAAGGIDWKSFAK
                     "
     gene            16169..17626
                     /locus_tag="ACFOAE_000549"
     CDS             16169..17626
                     /locus_tag="ACFOAE_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFC6884096.1"
                     /translation="MHKILPIAHVLSRLGMLFSFILLIPAALSYAFSDGAYTAFATTA
                     TVTLSGSCIVRLATLRFRRELRPRDGFTLVLMLWLAFAAMAAMPMYLYFPNMGFTDAF
                     FESMSGLTTTGATVIPHVDGLAPSVNFWRHMLNWLGGMGIIVLAVAILPMLGVGGTQL
                     FKAEIPGIDKESKMSPRISQVAKKLWFGYTLITILAAACLHFAGMGWFDAVCHAMATL
                     SLGGFSTHDASIAYYNSPLIEAVIIVFTIVGGINFANHFAALNSRSLKTYWKDEECRT
                     MLLLLSGSILAAALYLWHTGYYAGFTESLRYTAFNFVSIGLANGLANTDFAQWPLLIS
                     LWMFFLANILANSGSTGGGIKTIRALVLFKFSLREMMVLLHPKAVRTVKISGKAIPDR
                     LALTVMSFIFIYFMTVVLFSFLLMASGMEFTTAFTAVIACITNAGPGLGEVGPAGNYA
                     GLDVMQKWICVTAMLLGRLEIFTVFILFTPAYWKK"
     gene            complement(17667..18056)
                     /locus_tag="ACFOAE_000550"
     CDS             complement(17667..18056)
                     /locus_tag="ACFOAE_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884097.1"
                     /translation="MWKISKENCEDLGFAIVCMFYDAINLSEFKLWLDIVVRDTPIDT
                     IPLYIFDLIDFDKSIGEIYDVIGVVNYGYISNDQKNALTGIAFLRGIDVYDPPISKEK
                     ALKALEKYPEIYQRFQHFFPFVELPLL"
     gene            complement(18238..18639)
                     /locus_tag="ACFOAE_000551"
     CDS             complement(18238..18639)
                     /locus_tag="ACFOAE_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884098.1"
                     /translation="MKIKPLQFSNNNHRFYVDKICVTEQDVNILASDRNYELNIEIFI
                     DNIIHFQITDESYKVKFSEYLFENKEKNDWDRNPAINYFFEIIDDSYMDWLKEESFDF
                     FEKKYYKAYIFFFSDSVIEVISSTEPVFYSK"
     gene            complement(19082..19618)
                     /locus_tag="ACFOAE_000552"
     CDS             complement(19082..19618)
                     /locus_tag="ACFOAE_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HFC6884099.1"
                     /translation="MDYNQTVLSHLQNFWKHHDIKGFTWALGRIVEELPDFQVFQVIP
                     NHEDEPWVYVSSGIGQFLEQEFFIISPFETPEHIETLAMLASASMHYPDRFQLGKTVN
                     IGRPWVEQSSFQHFLISLPYPYGQELEYMDNVRFFWLLPITQPERLFLNTHSVEDLET
                     RFDELGIDYLDINRASVI"
     gene            complement(19699..20244)
                     /locus_tag="ACFOAE_000553"
     CDS             complement(19699..20244)
                     /locus_tag="ACFOAE_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004463655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HFC6884100.1"
                     /translation="MIIVEHLEHYLGEIESGIKCLDRRYHLSVSVFPSQPYKGVTTFS
                     TLGLNRYDLNYKSRFELIFTCSEEWNKENIAAFLSGVAEYLIDNRQPILRGEIIQLPR
                     VIIEGSKMDALYVSAPFYFDDDFQVCYGEHYNIVFPLLVPLYKQEAELVEKKGWNAFE
                     QFLLDNEVDNLSDMNRKPFAW"
     gene            complement(20365..20637)
                     /locus_tag="ACFOAE_000554"
     CDS             complement(20365..20637)
                     /locus_tag="ACFOAE_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884101.1"
                     /translation="MMSVKELFKVILDENKDFPIRTIHRTPMGILPKPVALSIVQYEN
                     DPGFYLFYLDETGQEQTDTYHDTLDSAFEQAEFEFGISKEEWMQSP"
     gene            complement(20641..21309)
                     /locus_tag="ACFOAE_000555"
     CDS             complement(20641..21309)
                     /locus_tag="ACFOAE_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HINT domain-containing protein"
                     /protein_id="HFC6884102.1"
                     /translation="MVKTADGYKAIAHIQAGDRVLSKDEASGETGYKPVTARYGNPYR
                     ETVYIEVSDGIGNSQTLVSNKIHPFYSQGKWIQAGRLKKGDTLLSESGAKQTVQNITL
                     KQQPLKAYNLTVADWHTYFVKGNQAETEGVWVHNSCPPKRAPEYHAGTVSESNFLNAA
                     EKWLGENYKSYPNGRYVSQDGMRQVRYGYHETNSSTHHGHFESYDKPNGRVIENSAVT
                     IIRD"
     gene            complement(21440..21817)
                     /locus_tag="ACFOAE_000556"
     CDS             complement(21440..21817)
                     /locus_tag="ACFOAE_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 41 family protein"
                     /protein_id="HFC6884103.1"
                     /translation="MCEFKDFRRNIPCFEEYDENSFIGKWYDDGVWDDEEYWKLENAL
                     IEVRRKYPYPMDIPRDIVIGIGTIIEFLMVPNWKLFTIKSSPWLPKSVKIDERYERFR
                     VMLRYIFTEIDIVNVRFDYYNKK"
     gene            complement(21886..22341)
                     /locus_tag="ACFOAE_000557"
     CDS             complement(21886..22341)
                     /locus_tag="ACFOAE_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884104.1"
                     /translation="MVDAVVKTPEFLPFTSVGIFRFGADITQYKNILETFMYEPPDEF
                     GTEYYESPDSNLLISVEKNKIISIFCYQELYFMGVNIIGLNFEDFKQLFHHPKSYGVD
                     KYYLSNESYPTYVYEFDEIGVQAWEAKGKIVTIIAGGKDNYSTEPYYDE"
     gene            complement(22529..22801)
                     /locus_tag="ACFOAE_000558"
                     /pseudo
     CDS             complement(22529..22801)
                     /locus_tag="ACFOAE_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951299.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin-type HINT domain-containing
                     protein"
     gene            complement(22843..23220)
                     /locus_tag="ACFOAE_000559"
     CDS             complement(22843..23220)
                     /locus_tag="ACFOAE_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 41 family protein"
                     /protein_id="HFC6884105.1"
                     /translation="MCEFKDIIRNVPYFEGYDENSFIGKWYDDGVWDDEEYWKLENNL
                     IEVRKKYPYPMDIPRYVVIGIGTIIDFLMVPNWKLFEIKASPWLPDSVGINERYERLK
                     TMLRYIFTEKDIVNVRFDYYNKK"
     gene            complement(23251..23649)
                     /locus_tag="ACFOAE_000560"
     CDS             complement(23251..23649)
                     /locus_tag="ACFOAE_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 41 family protein"
                     /protein_id="HFC6884106.1"
                     /translation="MCEFKDFRRNIPCFEEYDENSFIGKWYDDGVWDDEEYWKLENAL
                     IEVRKKYPYPMDIPRDIVIGIGTIIDFLMVQNWKLFEIKASPWLPKSVKINERYERFR
                     VMLRYIFTDLDVDDWKFFYFPIQHSKGRLR"
     gene            complement(23655..24332)
                     /locus_tag="ACFOAE_000561"
     CDS             complement(23655..24332)
                     /locus_tag="ACFOAE_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hint domain-/BECR-fold containing toxin"
                     /protein_id="HFC6884107.1"
                     /translation="MVKTADGYKAIARIRTGDRVFAKDEASGKTGYKPVTARYGNPYQ
                     ETVYIEISDGIGNNQTLISNKIHPFYSQGKWIQAGRLKKGDTLLSESGAKQTVQNITF
                     KQQPLKAYNLTVADWHTYFVKGSQAETEGVWVHNACPPRKTPSTPVYGNDSEAYAAAK
                     KLGYRKIKERTRNDAAIFKKGKSYISRDVDSHNGGAWKEASSPKNLNRKETRNGTFDK
                     NLNRIGD"
     gene            complement(24466..24783)
                     /locus_tag="ACFOAE_000562"
     CDS             complement(24466..24783)
                     /locus_tag="ACFOAE_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884108.1"
                     /translation="MNILPSWLRVGMNIAMLGMIHSDIRLITVDYEEGRRFLKIKNYL
                     SREAITEDHEDMEYLITELWSMCGEYFDEADFECIYSNHSSMELNQINGAVFRRKELI
                     SQA"
     gene            complement(24786..>25897)
                     /gene="mafB"
                     /locus_tag="ACFOAE_000563"
     CDS             complement(24786..>25897)
                     /gene="mafB"
                     /locus_tag="ACFOAE_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polymorphic toxin MafB class 1"
                     /protein_id="HFC6884109.1"
                     /translation="EEHAPFDNHAADSASKEQGNVDEGFTVYRLNWEGHEHHPADAYD
                     GPKGGNYPKPTGARDEYTYHVNGTARSIKLNPTDTRSIRQRISDNYNNLGSNFSDRAD
                     EANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFISAGEALGIGDILYGTRYAIDKAA
                     MRNIAPLPAEGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAK
                     VAKLAKAAKPGKAAVSGDFSDSYKHNTASRLSQSVDGEMFQTRNVDFKAKSIGTKIHD
                     GAQGKHISGHRNYIEGKSTLNQNINPQELLNGIHSGAYPVISKGARGNPVVDFGYPIG
                     SDGKSGLSTNFGTIHSGKNGVHIVPANPKTIKKVQ"
BASE COUNT         6370 a         7089 c         5839 g         6599 t
ORIGIN      
        1 tgttaatcca ctataacaaa attcagaatc aagacagggc aataccatac tggttttgca
       61 ccaacccgct ataaaattgc ataaaaaaaa tagacgctgt aaaacacagc gtctattttt
      121 tatctggcgg agtaagaggg attcgaaccc tcgatgcagg ttgaccccac atgcttcctt
      181 agcagggaag tgccttcagc ctctcagcca ttactcctaa ggaagctgta actataatca
      241 acttttccga taccgtcaag gaaaaatgga aagcaaatat taatcttttg aaataaaata
      301 agatttaccc tgattatacc caatcaggca cttcttttct tcctgaatgg aaatattcct
      361 gactgccaca tcctcaagca aaatgctttt gtgcatcctg tttgatttcc tgaaaccacg
      421 cgtcttcagg aaaacgtgca agcgcgacat ccaatgttga cagcaggttt tgcgacaggg
      481 ctttggtcag gtattcctcc tcgttggctt ctgccgcttt gtcgggctgt tgtgccaaac
      541 cgtcggcacg ggctttgtgt ccgtgtgcca aatatagtgg attaacaaaa atcaggacaa
      601 ggcgacgaag ccgcagacag tacagatagt acgacaaggc gaggcaacgc cgtactggtt
      661 taaatttaat ccactataat tgagcgcggt aattttttgc gcccaaagct gcggtatgtc
      721 gggattgtct tcaatcatga cggaaaggat ggatacggcg gtcgccagcc tgccgccgtt
      781 cattctaagg tcgagggaac ggttgggcgg cagggtgctg agtgtttctg ccattctgaa
      841 ccaaaattcg ccactggctt cgtcgggtgc gttcaattta agcatttcat agtgaacctc
      901 ctgatcatcg ttttgcacga gaccccatac ttcggcaagg attttctgtt cttcccggct
      961 caagtgttgc cacttttcaa tatgttgctg catatctttt ccctttgaac ctgttttata
     1021 cggtctgaaa tacagcgcga accctatcca aatcttcctg cgtatccaca ccggcggcgg
     1081 gggcttcttt ggcggtttcg acggcaatcg ggtagccgtg ccacaggacg cgcagctgtt
     1141 ccagcgattc gatggtttcc agcggcgaaa cgctcatttc ggcatagcgt tgcaggaagc
     1201 cggcgcggta agcgtagatg ccgatatggc gcaggacggc ggtttcagac ggcatttcgc
     1261 gttttcctgc acgcatcgca tcgcgcggat agggaatcgg ggcgcggctg aagtagatgg
     1321 cgttgcggtt tttgtcgagg acgactttga cggcattggg attcatcaat tcgtcgaaat
     1381 cgtgcaattc gtgtgccgca gttgccatct gtacgttgtt ttccaccaag acttcggcag
     1441 tgcggtcgat gagttcgggg gcaatcagcg gctcgtcgcc ctgtacgttg acaaccacca
     1501 gatgcggcgg cagcttcagc gcggcagagg cttcggcaag gcgcgtcgtg ccgctttcgt
     1561 gccggtttga agtcatgacg acttcgacgc cgtgcgcctg acaggccgtc tgaatatcgg
     1621 gatggtcggt ggcaacgacg acgcgcacag ctttactttt tgccgcctgt tcggcaacgc
     1681 gcacgaccat cggtttgccg tggatgtccg ccaaggcttt tccgggcagg cgcgacgaat
     1741 ccagccgcgc cggaatcaat acgacgaatt cggtcatgct tcgagttcct cttcgcccaa
     1801 cggacgcgct tcgttttcca gcatataggg aatgccgtct ttaatcggat aggcaagctt
     1861 cgcctgacgg ctccacaatt cctgtttgtc ctgatgatat tccagcctgc ctttggtaac
     1921 ggggcagacg aggatgtcta agaatttttt ttccataggg ttgctttcgg gtttgatggt
     1981 tcaatcaatc ggatgccctc ttcaatattt cagacggcta tcatttattt ctgatgcctt
     2041 ttcccaacct gtccggcttg tttacagccc gcatcgggat ttttaccgcc gcagatgatg
     2101 cgccgcaact cttccgtaaa cgcgggcaga tgatgtcgcg cgattttccc tgacaatgca
     2161 gtccaagata ctgctatttc actcatcgat ttcttgatta agcgcggatt tttggcaacg
     2221 acggactgac cgacaggcga accgtaaaag gcaatcatgc cgtcaatttc ttcttgcgtg
     2281 tatatctcac gggcattctt caataaagta ttacggacag cctgtttcac ttcgggcgta
     2341 atcaaatctt tcaaaacatt ctcacgatag cggttaaagg cttttgccgc ctgatctttt
     2401 ttcgcttccg gcatttcggc aagggctttg tccgcatacg gtttaaatcc ggcattaaag
     2461 ccctcaatca tatttttttc tatatcccgg tcaaaattct gcgtatccag ccaacgcgcc
     2521 aacgacgcgt cgctgggcgg ggcggcaaaa gcgttggtgc acaatgccag cgtggcgaag
     2581 ggcaataaca aggttttcaa tttaatattc aatcctttaa caaatgatta atgcagataa
     2641 aaaatacaac cggcttccat tattcctgcg caggcgggaa tccggagatt taggacttcg
     2701 gaaacctctt ggtcatttct gaaaaatcaa gatccagatt cccacctgcg cgggaatgac
     2761 ggcgtagggc gttcttattc cagtccgtta tcacttcatc caaaccgcgc tttcagacgg
     2821 ccttcggtac atcttccaac cgctccaaca caaacgccgc caaatcaggt tcgattatcg
     2881 cacaaacggg caacacccaa acattatcgg tgcaaatgcc gtctgaaaat ttgaccgcat
     2941 ctttctccgt aataatgacc gcgtccgcat cgggcaaatc tgccgccgaa atgtcggcgt
     3001 ggtcaggcag cgcgacggtt cgcttcacgg taatgcccat attccgcaac gaatcaaaaa
     3061 accgcgccgg cttggcaata cctgccacgg cgacgacggt ttgatttttc agacggcctg
     3121 tgtccagtat ttcggacgga ttgttcaaac ggtaaatccg tcccgcttcg atacggctgt
     3181 gaaacatatt ttcagacggc ctaaacagcg catccgcctt gccgccgctg acgacgaccg
     3241 catccaccga atccagccgc aacaaaggtt cgcgcaaact gccgttgggc agtaaatcca
     3301 aatccgtgcg ccccgtatcc gccgccggaa acaccgcgat ttccacatct cgccgcaggg
     3361 cgtaatgctg caaaccgtcg tccgccacaa tcagtccgat gtcgggatgc gccgccagca
     3421 acgccctgcc tgcctctgca cggctgctgc ccaccgccgt cggcgcaccg gttttgcgga
     3481 acagcagcaa aggctcatcg cccgcatctt ccgctcggct ctcagcattc aatacatgaa
     3541 ccgccttgct cttgcgcccg tagccccggc tgatgatgcc gaccttgacg cccttttcct
     3601 gcaaacccga caccagcgcg gcaacaatcg gcgttttccc cgtcccaccc gcgtgaatat
     3661 tgccgaccac gaccacaggc acgggcagct tttcgctttg ccgttttccc gataaaaaat
     3721 ccgtccgccg ttttgccgca attttggcaa acagcccgga gagcggctta agcagaaaag
     3781 acaaaaccgg ataaggtttt tgccaatgcc gttcgataac ggtatgaaat ttgaaacaat
     3841 tcggcatatt cgatacaaat cctcgaagca aaatcagccc ggggcattaa tcatgcgtac
     3901 ccgatacaga cccacctata aacaacgcga agaccaaacc gataagcgaa ccaatcaggt
     3961 aaataagcaa ctgcgcttta cagaaattgg cgcggttcgg gttgcctctg ccgaacaccc
     4021 aaacaaaaat tgaccaaagg aatcatgaaa acaatcatcg tcaacaccca ctgccctgtc
     4081 gtcatgacgg gaggcggttt gttttgaagt ctcgggcata tcgccaatat gataacggac
     4141 aggtttcatc tctttcattt tccagtatct ttcatttata gtggattaac aaaaaccagt
     4201 acagcgttgc ctcgccttag ctcaaagaga acgattctct aaggtgctca agcaccaagt
     4261 aaatcggttc cgtactattt gtactgtctg cagcttcgtc gccttgtcct gatttttgtt
     4321 aatccactat atcaatctga cagcaaaata ccgcctgaaa acagttcaga cggcatttta
     4381 aaccgcaaac ggcttacagc ttccattcgc tcagcttggc agcgtaagct tccaaatctg
     4441 caatcggacg ggttgccacg ccgctttcca tcgctgcttt ggcggcagcc gtagcaacgc
     4501 gcggcagcag gcgggaatcg aacggagtcg gaatcaggta ttccgcgccg aattcaaatt
     4561 tcttaccgta agcggcaacc acttcttcgg ttacttcttc catcgccaaa tccgccaaag
     4621 catacacgca ggcgcgtttc atttcttcgt tgatggtcgt cgcgccgaca tccaacgcac
     4681 cgcggaagat gaacgggaag cacaatacgt tgttcacttg gttcgggaag tcggaacggc
     4741 cggtaccgat aaccacgtcc ggacgggttt cttttgccag cggcggcaga atttccggat
     4801 tcgggttggc catggcgaac acgatgggtt tttcgttcat ggtgttcagc atttcaggcg
     4861 tcagcaggtt cgcgccggag aggcccaaga agatgtcttt gcctttgacg gcatcggcaa
     4921 gcacgcgctg gccgttgtct tcaatggcgt agaactgttt ggactcgtcc atacggtctt
     4981 tgtcttcgcg ggtttggtaa attacgcctt tggagtcgca aacggtcacg ttttcgcgtt
     5041 tcaagcccaa atccagcaat tggttcaagc aggcaatcgc ggccgcaccc gcaccagagc
     5101 aaaccaaggt cgcttcttcg attttacggc cggtaaaacg cagggcgttc aatacggcag
     5161 cggcggtaat gatggccgtg ccgtgctggt cgtcgtggaa tacggggatt ttgcagcgtt
     5221 tgcgcaattc gcgttcgatg tagaaacact cgggtgcttt gatgtcttcg aggttgatgc
     5281 cgccgaaggt cggctctaaa gcggcgatga tgtccacgag tttttgcggg tctttttcat
     5341 cgatttcgat gtcgaacacg tccacaccgg cgaatttttt gaacaatacg cctttgcctt
     5401 ccatcacggg tttgcccgcc agcgcgccga tgtcgcccaa gcctaaaacg gccgtaccgt
     5461 tggaaatgac ggcgaccaag ttgcctttag cagtgtattt gtaggcattt tgcggatcgg
     5521 catggatttc catacaagga gcggctacgc ccggagagta cgccaacgcc aaatctttgt
     5581 cggtcgccag agatttggtc ggggtaacgg aaattttgcc cggaacgggt aattcgtgga
     5641 acttgagggc ggcttctttc aatgagtttt ccatgtgtca atcctgttgc gagaaaaaga
     5701 tttgaatcgg actgtccgaa acgctttcgg gtcatcatgt tacgggcggt tcgttaatat
     5761 tgccgacgca tcctgccttg taaccgagcg taattctatc atgccgaaag tttggcgcat
     5821 accgccattt tcacctgcgg cactgccgtt tgattttcgg cgcgggcgga tgcgcttgtt
     5881 tcaatatttg ccgcatcaac agccgaaatg tctgtccaac actttttcta tgctgtttct
     5941 gacttcatcc aagccgaggt tactgtcgat aacggcgtaa cgttccggac aggcggcggc
     6001 acggttcaga taaacgctgc gcacacgcat gaagaaatct gcctgttcct gctcgaaacg
     6061 gtctttctcg cgcgtctgcc cgatacgcgc catcgacact tcgagtggca catccaacag
     6121 cagggtcaaa tcggggcgca aaccgccctg cacccaatgt tccaaaattt caatgtcttc
     6181 agacggcatc ccccgcccgc cgccctgata ggcgaaggtc gcatcggtaa aacgatcgga
     6241 tacgacgtgt atgccgtctg aaagcgcggg caatatcacg tcttcaatat gctgcattct
     6301 ggcggcgaac atcatcagtg tttccgcacg caaaccggct ttggtttcag ggttgagcag
     6361 gatttcgcgc aaggcctcac cgaccggcgt tccgcccggt tcgcgcgtga acagcacggg
     6421 cagccccctc cgttcaaacc atgccttgat gacggcaagg ttggtggatt tgccggcacc
     6481 gtctatgccg tccaaagtga tgaattgcgg tttcatgctt gcagttccgg taagggtatg
     6541 ccgtctgaaa acacaaactt ttcagacggc atggtttatt ttttcaaaat atatttgcgg
     6601 acggcggcat tgtgttcggt caaatcatgg ctgaactggc tcaagcccgt accgtccatt
     6661 ttagaaacaa aataaaggta tttttcgcca gacggatggg cggcggcatc aagcgcggcc
     6721 ttgccgggca gcgcaatcgg ggttggcggc agaccgccgc gcgtgtaggt gttgtacggc
     6781 gtgtcgcggc gcaggtcggc tttacggatt ttgcccttgt atgccgcacc catgccgtaa
     6841 atcacggacg ggtcggtttg cagacgcata ccgattttca gccggttgac gaagacggaa
     6901 gcgacatggt cgcggtcggc ttcatgcccc gtttcctttt cgatcaggct cgccataatc
     6961 agcatttcat aagggttttt ataaggcagc ccgtcctgcc tgcctgccca tacctcgttc
     7021 agacggcgtt gcatcgcctt gtaggcggtt tggtaaatct gcaaatcgct gccgcccgca
     7081 tcaatttcgt aactgtcggg aaaaaactgc ccttcaggat tgccgctgaa ggcatcgggt
     7141 gcaacttccg ccatcagttt ttcattgctc cagcctttgg tgtcgtgttc gatgtcgggc
     7201 gttgcgtcga tgactttcct catatgcgaa aaacgcgaac cttcgataat ctgcacggta
     7261 acggaatccg gcctgccgcc gcgcattttc tgcaagatat cccaagcaga cacttccgaa
     7321 ggcagtctgt acgtccccgt atgcagcctg ttgtgcacac ccaaaacgta ggccgccgcc
     7381 gtcaaaacat gcctgctgaa cacgatgcgg tcttcggcaa gtttcctgcc gaccgacgaa
     7441 ataccctggt ttttggcaat tttaatcctg tatgccctgc cgttgtcttt agggacgaaa
     7501 agcagcgcgg cgaaaacggc tgccgatacg gtcaaaaaaa cggcagacca tttcaacaat
     7561 tttctcaaca tggtaggatt cccagcattc ggaatacgtc ttaaaattcg ggcgacagta
     7621 taacccaaat tgcccgccgg acaggaagaa catcatggac aatcacgccg aagcacactg
     7681 gcaaaacggc tggcttcaaa gcatacgcca taccccgtcg cccaatttca gcccgaggga
     7741 aacgggggaa acggtttccc tgatcgtgtt gcacaacatt tcgctgccgc cgttcgaata
     7801 tggtacggat gcggtggaaa agctgtttgc caaccggctc gaccccgacg gacatccgtt
     7861 cttcagcctg atacacactt tgcgcgtatc cagccatttt ttaatcaaac gcgacggcga
     7921 aacggtacag ttcgtttcct gcgacaatat ggcataccat gccggcgtat cctcgtttcg
     7981 cggacgggaa aaatgcaacg cattttccat cggcatcgaa ctggaaggct gcgatttcga
     8041 accctttacc gaagcgcaat accgttcgct cgaagccttg ttggacgcaa tctgccgccg
     8101 ctaccccatc acggcggtaa cggggcacca agacatcgcg cccggccgca aaaccgaccc
     8161 cggtcatttt ttcgactggc ggcggatacg ggggaaaggg tttcccgtgg acagaaatgc
     8221 cgtctgaaaa ccacagattt tagacggcat ttcggaaaat ttccgcttat ttcgacacac
     8281 tgctgtcaga ccctgcaatt ttcgttataa ttcaaacgtt ataaccggcc gttccatcag
     8341 actgccggaa acgcaagccc gatttaaccg cagtacccgc acttcgcgca tcctgcatcc
     8401 cgaaatttaa agtgattgcc atgatttaca tcgtactgtt cctcgccgcc gtcctcgccg
     8461 ttgtcgccta caatatgtat caggaaaacc aataccgcaa aaaagtgcgc gaccagttcg
     8521 gacactccga caaagatgcc ctgctcaaca gcaaaaccag ccatgtccgc gacggcaaac
     8581 cgtccggcgg gtcagtcatg atgccgaaac cccaaccggc ggtcaaaaaa acggcaaaac
     8641 tccaagaccc tgctatgcgc aacctgcaag aacaggatgc cgtctacatc gccaagcaga
     8701 aacaggcaaa agcctccccg ttcaaaaccg aaatcgaaac cgccttggaa gaaagcggca
     8761 ttatcggcaa ctccgcccac accgtttccg aaccccaaac cggacattcc gcaccgaaac
     8821 ctgccgacgc gccggcaaaa cctgcacccg ttccgcaaac acctgcaaaa ccgctgatta
     8881 cgctcaaaga actgtcaaaa gtcgaattac cctggtttga cgtgcgcttc gacttcatct
     8941 cctatatcgc gctgaccgaa gccaaagaac tgcacgcact gccacgcctt tccaaccgct
     9001 gccgctacca gattgtcggc tgcaccatgg acgaccattt ccagattgcc gaacccatcc
     9061 cgggcatccg ctatcaggca tttatcgtgg gtattcaggc agtcagccgc aacggacttg
     9121 cctcgcagga agaactctcc gcattcaacc gccaggtgga cgcattcgca caaagcatgg
     9181 gcggtcagac gctgcacacc gaccttgccg cctttatcga agtggcttcc gcactggacg
     9241 cattctgcgc gcgcgtcgac cagaccatcg ccatccattt ggtttccccg accagcatca
     9301 gcggcgtaga actgcgttcc gccgtaacgg gcgtgggttt cgttttggaa gacgacggcg
     9361 cgttccacta taccgacacg tcgggctcga ccatgttctc catctgctcg ctcaacaacg
     9421 agccgtttac caacgccctt ttggacaacc agtcctacaa aggcttcagt atgctgctcg
     9481 acatcccgca ctctccggca ggcgaaaaaa ccttcgacga tttgtttatg gatttggcgg
     9541 tacgcctgtc cggccagttg aacctgaatc tggtcaacga caaaatggaa gaagtttcga
     9601 cccaatggct caaagacgtg cgcacttatg tattggcgcg tcagtccgag atgctcaaag
     9661 tcggtatcga accgggcggc aaaaccgcat tgcgcctgtt ctcctaaaat cgaatgcaat
     9721 caaagcggat atgtcgttac ggcatatccg ctttttttcg ggtaaaattc agctgttttc
     9781 aacctatcat ttttcagacg acctttgccc gtttcatccc gtatcagaca aaggtcgtct
     9841 gaaaaccttc tctcatgaat ccaaactcaa aacataacac taactttacc aatcttctta
     9901 aaccgtctga tagtgatata aaacaatttg ccgcacaaca catctgccgc ctcaccgacc
     9961 tcctcaaccg ctacgcctac gaatactaca ccctcgacgc gcccagcgta cccgatgccg
    10021 aatacgacaa attgttccgc gaactcgaag cgttggagtt aaaccatccc gagctcaaac
    10081 tgcccgacag cccgacccag cgcgtcggcg gcgagccttt ggcgggattt gccgaagtac
    10141 gccacgaagt gccgatgctg tcgctgacca acgctttttc cccgcaagat gaaaacggcg
    10201 tgttcgacca tgccgaaatg tacgccttcg accaacgcgt gcgcgacggc ttggacggcg
    10261 gcaatcccga atacgttatc gaacccaaat tcgacggcct cgccatcagc ctgctctacc
    10321 gcgacggcgt attggtgcag gcggcaacgc gcggcgacgg cacgacgggc gaagacgtta
    10381 cccaaaacat caaaaccgta tccaacatcc ccttgcggct gcacggcgaa aatacgcccg
    10441 aactcatcga agtacgcggc gaagtactga tgcaaaaagc cgattttgcc gccctcaata
    10501 aaagacaagc cgaaaacggg caaaaaccct ttgccaatcc gcgcaacgcc gccgccggca
    10561 gcctacgcca actcgattcg cgcatcactg cgcaacgcaa actgcacttt ttcccctact
    10621 ccgtcgcccg ccggcaaggc ggtttcgtcg cggaagaaca catccaagaa ctcgcctatt
    10681 tccaagcact cggcttcagt ctgcccaatg gcaatttcgg ctgtttcaaa aatatcgacg
    10741 aagtattggc gttttacgaa cacatgcagc aaaaacgccc cgaactgccc tacgaaatcg
    10801 acggcatggt ggttaaagtc aacagcctgg cgcaacagcg cgaactcggc ttcatctccc
    10861 gcgcgccgcg ctgggcgatt gcccacaagt tccctgccga agaagccctg accgtcgtcg
    10921 aagcgattga cgtgcaaatc ggcaggacgg gcgcggtaac gccggttgcc cgattacaac
    10981 ccgtattcgt cggcggcgta accgttacca acgccaccct gcacaatcag gacgaagttt
    11041 cccgaaaaga cgtgcgcgtc ggcgataccg tcgtcgtgcg ccgcgccgga gacgtgattc
    11101 ccgaagtcgt gcgtgtgatt tttgaacgcc gcccgatgca ggaaaccgcc gttgctgttt
    11161 cagacggcat cgggcatcgg caggacgatt tgtttgccga agcaccggct gcaaaccaaa
    11221 cccaatccgt tccgctctac aagccctacc gcctgccgac ccattgcccc atctgccgca
    11281 gcgaaatcga acgcgaagaa ggcgaagccg tcgcccgatg cagcggcggt atgctttgtc
    11341 aggcacaacg cgcgcaaggc ttaatccact tcgcctcgcg caaagccatg gacatcgacg
    11401 gcttgggtga aaaacaaatc gaacagcttg tcgcccaaga cctcgtccgc cacttcgccg
    11461 acctctaccg cctcgatatt ccgaccctgc aaaaaatgaa ggaaacggcg gacaaaaccg
    11521 ttgccgaatc ggatcaaatg ccgtctgaag gcagttcggt cggtgcgtcg ggcaaacata
    11581 aaaaacaacc gaccaagtgg gcggaaaaca tcctcgcagg catagaatcc ggcaaaacgc
    11641 ccgaactcgc gcgcttcctg ttcgcgctcg gcatccgcca cgtcggcgaa cgcaccgcca
    11701 aaacgctggc acaggcattc ggcacattgg aacgcgtccg ccgcgccccc gaacccgtcc
    11761 tcgcctgcct gcccgacatc ggtacggtag tggcgcgttc cattgcccac ttcttcgccc
    11821 aagccgaaca gcaggcgatg atagacgagc tgctcgccgc aggcgttgcc ccgcaagccc
    11881 aagccgtcag cctgcctgcc gcacaatatg ccgaaccgca acgctggatt gcccgcctgc
    11941 ccggtttcaa aattagcgaa aacaaagccc aagccttatg ggaactcgcc ggcaaaagta
    12001 tagagggtct gcaaaccgac aaatccctcc ccgccgactg gcaagcatgg cgcagcgaac
    12061 cacaaaacgc cgccctactc gaaaacctga aaaccttctt cgcgcaaatg ccgtctgaag
    12121 acgaggcggc gcaaggttca gacggcatca ataaagccgt agcgggcaaa accttcgtgt
    12181 taactggcac actgcccacc ctcaaacgcg accaagccca atccctaatc gaagccgcag
    12241 gcggcaaagt ttccggcagc gtgtccaaaa aaaccgatta cgtcgtcgcc ggagaagccg
    12301 cgggcagcaa gctggaaaaa gccaatgcct tgggcgtttc cgtcctcagc gaagccgaac
    12361 tgcttaccct gctcggctga acccatgccg tctgaaccgc cttcagacgg cattgcccac
    12421 ttttccgaac cacaccatgc acaccatttc ctttccaaac cgcacccgac tcaccgccct
    12481 gccgcccctg tcgctttaca tccacatccc gtggtgcatc aaaaaatgcc cgtattgcga
    12541 cttcaattcc cacagcctga aaaacggatt gcccgaagcc gcctatatcg acgcgctgct
    12601 gaccgatttg cagcttgaat tgcccaatat ttggggcagg ccggtggaaa cgatcttttt
    12661 cggcggcggt acgcccagcc tgtttcaggc ggaatcgatt gaccgtttgt taagcggcgt
    12721 gcgttcgctg ttgcgcttgc agccggaagc ggaaattacc ttggaagcca atccggggac
    12781 atttgaaatc gagaagtttc aaggatttaa agacgcaggc atcacgcggc tttctattgg
    12841 cgtacagagt ttcaacgacg atatgctctc aaggctgggg cgcgtccaca acggtaagga
    12901 agccttaacc gctatcgata ccgccttgaa attatttgat aaagtcaata tcgacttgat
    12961 gtatgccctg ccgaaccaaa ccgttcagac ggcattggac gacgtacaaa ccgccatcgc
    13021 tacgggtgcg acccacatca gcgcgtatca tctgacgatg gaaccgaaca cgccgttcgg
    13081 tcatacgccg ccgaaaggtt tgccgcaaga cgaagccgcc ctcgacatcg aagacgcggt
    13141 acacggcgcg ctggaaagcg cgggttttgt ccactacgaa acatcggctt ttgcgaaacc
    13201 agccatgcag tgccgccaca atttgaacta ctggcagttc ggcgattatt taggcatagg
    13261 cgcgggcgct cacggcaaaa tttcctatcc cgaccgcatc gagcgcaccg tccgccgccg
    13321 ccaccccaac gactacctcg ccttaatgca aagccaaccg agtgaagccg tcgaacgcaa
    13381 aaccgttgcc gccgaagatt tgccgttcga gtttatgatg aacgccctgc gcctgaccga
    13441 cggcgtaccc gccgcgatgt tgcaggagcg cacgggcgta ccgagtgcca aaatcatggc
    13501 gcaaatcgaa acagcaaggc aaaaaggcct gctggaaacc gaccccgccg tattccgccc
    13561 gaccgaaaaa ggacgcttgt ttttaaacga tttgctgcaa tgttttttat agtggattaa
    13621 caaaaaccag tacggcgttg cctcgcctta gctcaaagag aacgattctc taaggtgctg
    13681 aagcaccaag tgaatcggtt ccgtactatt tgtactgtct gcggcttcgt cgccttgtcc
    13741 tgatttttgt taatccacta tataagcgca aacaaatcgg cggccgcccg ggaaaacccg
    13801 ccccgaacgc gtccggaaaa tatgcttatc gatggaaaac gcagccgcat cccccgccgg
    13861 gcgtttcaga cggcacagac gccgccggaa atgtccgacg cttaaggcac agacgcacac
    13921 aaaaccgtat gcctgcacct gcaacaatcc gacagatacc gctgtttttt ccaaaccgtt
    13981 tgcaagtttc acccatccgc cgcgtgatgc cgccgccacc atttaaaggc aacgcgcggg
    14041 ttaacggctt tgccgtcggc aaagcagccg gataccgcta cgtatcttga agtattgaaa
    14101 atattacgat gcaaaaagaa aatttaagta taatacagca ggattcttta acggattctt
    14161 aacaattttt ctaactgacc ataaaggaac caaaatatga aaaaagcact tgccacactg
    14221 attgccctcg ctatcccggc cgccgcactg gcggaaggcg catccggctt ttacgtccaa
    14281 gccgatgccg cacacgcaaa agcctcaagc tctttaggtt ctgccaaagg cttcagcccg
    14341 cgcatctccg caggctaccg catcaacgac ctccgcttcg ccgtcgatta cacgcgctac
    14401 aaaaactata aagccccatc caccgatttc aaactttaca gcatcggcgc gtccgccatt
    14461 tatgacttcg acacccaatc gcccgtcaaa ccgtatctcg gcgcgcgctt gagcctcaac
    14521 cgcgcctccg tcgacttggg cggcagcgac agcttcagcc aaacctccac cggcctcggc
    14581 gtattggcgg gcgtaagcta tgccgttacc ccgaatgtcg atttggatgc cggctaccgc
    14641 tacaactaca tcggcaaagt caacactgtc aaaaacgtcc gttccggcga actgtccgcc
    14701 ggcgtgcgcg tcaaattctg atatgcgcct tattctgcaa accgccgagc cttcggcggt
    14761 tttgttttct gccaccgcaa ctacacaagc cggcggtttt gtacgataat cccgaatgct
    14821 gcggcttctg ccgccctatt ttttgaggaa tccgaaatgt ccaaaaccat catccacacc
    14881 gacaaagccc ccgccgccat cggcgcgtac agccaagccg tccgagcagg cgacaccgtt
    14941 tacatgagcg gtcaaatccc cctcgatccc gccacgatga ccgtcgtcgg caacggcgat
    15001 ttccgcgccg aagcgcgcca agtgttccaa aacctgcaag ccgtcgccga agcggcaggc
    15061 ggcacgctgg ccgacatcgt caaactcaac gcctacctga ccgacttggg caattttgcc
    15121 gtcttcaacg aagtcatggc ggaatttatc gccgagccct tccccgcccg cgccgccgtc
    15181 ggcgttgcct cgctgcccaa aggcgtgcag gtcgaagccg aagccgtcct cgttttgaac
    15241 gcataattcc acgttcggac tgcatgatat ttcaaaacca tgccgtccga accgcaacac
    15301 tttcccactt cacaacatct gcaatggcac attacgcaat cggcgacata caaggctgtt
    15361 tcgacgaact gaccgcgctg ctcggcaaaa tcggtttcaa ccacggcacg gacaccctct
    15421 ggctgacggg cgacatcgtc aaccgcggcc cgaaatccct cgaaacgctg caattctgca
    15481 tccggcacga aaacagcgtg caaatcgtcc tcggcaacca cgacctgcac ctgctcgccg
    15541 tcggctgcgg cgaaggcgcg cccaaacgca gcgacacaat cgaacccata ctcaaacacc
    15601 ccgacggaaa aaaaatgctc gactggctgc gtgcgcaacc gctgttgata cgcgagggca
    15661 gccgcgtgat ggtacacgcc ggcatcctgc cgcaatggcg catcgccaaa gccgaatcgc
    15721 tcgctagaga agccgaagcc gaactgcgcg gcaaaaaaca cgtcaaattc ttctccaaaa
    15781 tgtacggcaa caaaccggcc gcgtgggacg aaagtttgaa aggctatgcc cgcctgcgct
    15841 tcatcgtcaa cgccttcacg cggatgcgcg ccctgacctt taaaaacgaa ctggatttcg
    15901 actacaaatc cacagtgaaa aaaatgccgc cttacctgcg cccgtggttc aaagcccccg
    15961 accggcaaaa cctcgaccgc accatcatct tcggacactg gtcctcgctg ggctacacga
    16021 atgccgacaa cgtcatctcg ctggacaccg gcgcgctgtg gggcggacag ctgaccgccg
    16081 tcaacctcga aacggaagaa attacccaag tccaagccgc cggcggcata gactggaaaa
    16141 gcttcgcaaa ataacggacc gccccactat gcacaaaatc ctgcccatcg cccacgtcct
    16201 ctcccgactg ggtatgctgt tttcctttat cctgctgata cccgccgccc tctcctacgc
    16261 cttttcggac ggcgcgtaca ccgccttcgc caccaccgcg accgttaccc tttccggctc
    16321 gtgcatcgtc cggctcgcca ccctccggtt caggcgcgaa ctgcgcccgc gcgacggctt
    16381 caccctcgtc ctgatgttgt ggctggcgtt tgccgctatg gctgcgatgc cgatgtacct
    16441 gtatttcccg aatatgggct ttaccgacgc attttttgaa tcgatgtcgg gactgaccac
    16501 caccggcgcg accgtcatcc cccacgtcga cgggctcgcc ccctccgtca acttttggcg
    16561 gcatatgctc aactggctgg gcgggatggg catcatcgtc cttgccgtcg ccatcctgcc
    16621 tatgctcggc gtaggcggca cgcagttatt caaagccgaa atccccggca ttgacaaaga
    16681 aagcaaaatg tcgccgcgca tttcccaagt ggcgaaaaaa ctttggttcg gctacaccct
    16741 gatcaccatc ctcgcggcag cctgcctgca ttttgccggg atgggctggt tcgatgccgt
    16801 ctgtcacgcg atggcgaccc tctcgctggg cgggttttcc acccacgatg ccagcatagc
    16861 ttattacaac tcccccctca tcgaagcggt catcatcgtt ttcaccattg tcggcggcat
    16921 caattttgcc aaccatttcg ccgccctcaa cagccgcagc ctcaaaacct attggaaaga
    16981 cgaagaatgc cggacgatgc tgctgctgct ctccggcagc atccttgccg ccgccctgta
    17041 cctgtggcac accggctatt acgccggttt taccgaatcc ctgcgctaca ccgccttcaa
    17101 cttcgtctcc atcggattgg caaacgggct ggccaacacc gacttcgcac aatggccgct
    17161 cctgatttcc ctgtggatgt ttttcctcgc caacatcctc gccaactccg gctcgaccgg
    17221 cggcggcatc aaaaccatac gcgccctcgt cctgttcaaa ttcagcctgc gcgaaatgat
    17281 ggtgctgctg caccccaaag ccgtccgcac cgtcaaaatc agcggcaaag ccatacccga
    17341 ccgcctcgcg ctgaccgtta tgtccttcat cttcatctac tttatgaccg tcgtcctctt
    17401 cagcttcctg ctgatggcga gcggtatgga atttaccacc gccttcaccg ccgtcatcgc
    17461 ctgcatcacc aacgccggcc ccggcctggg cgaagtcggg cccgccggca attacgccgg
    17521 tttggacgtg atgcagaaat ggatctgcgt taccgccatg ctcttgggca ggctggaaat
    17581 cttcaccgtc ttcatcctct tcacccccgc ctactggaag aaataaaaaa tgccgtctga
    17641 aaacttttca gacggcatct tgtcctttaa agaagcggaa gctctacaaa aggaaagaaa
    17701 tgctgaaacc tctgataaat ttcaggatat ttctctaagg cttttaatgc tttttctttt
    17761 gaaataggcg gatcatagac atctatcccc cttaagaagg caatgcccgt taatgcattt
    17821 ttttgatcat ttgaaatgta accataatta acgactccaa ttacatcata aatttcccct
    17881 atactcttat caaaatcaat caaatcaaaa atatacaatg gaattgtatc aataggagta
    17941 tctctgacaa ctatatccaa ccataattta aattcagaaa gattaatagc atcatagaac
    18001 atacagacta ttgcaaatcc taaatcttca caattttctt tactaatttt ccacataatt
    18061 atttaccttt atccattgct tcccaaccga tacatccggt attttagctt ctccttttcc
    18121 gtcaaacact cctttggtta cctgctttgt gtcaaaaata ccgtctgaaa gccgaatatt
    18181 gtttcagacg gtattttgat tgttgggttt ttaatcagag ctttgtttga taatttgtta
    18241 ttttgaataa aatacaggtt ctgtcgagct gataacttct attacagaat cgctaaaaaa
    18301 gaaaatataa gccttataat atttcttttc aaaaaaatca aaactttctt ctttcaacca
    18361 gtccatataa ctgtcatcta ttatctcgaa aaaataattt atagcaggat ttctatccca
    18421 atcatttttt tctttatttt caaataaata ttctgaaaat tttactttat aagattcatc
    18481 tgttatttga aaatgaatta tattgtcaat aaatatttca atatttaatt cataatttcg
    18541 gtcggatgcc aaaatgttca catcttgttc ggtaacacaa attttgtcca cataaaatct
    18601 gtgattattg ttagaaaatt gtaatggttt aatcttcaca atcgttttcc atatctaatt
    18661 tttgttttct tattgccctg ccggataaag caggtctgcc tccgtactgt ctatcctcac
    18721 atttactttc ctgccatcgg cttttatctc cccagtttta ccgtttttgc caactttgcg
    18781 gctttggcgg cggcaatgtt gaaggcggct tcgacggttt cggcggcatt ggggttgacc
    18841 cgtactcatc cgcaaacggc aacacgacgg acggtgtttg cttttcagcc gtctgccgtt
    18901 ttgaccaagg tgctgccgtg gaaagagcag gtgtaggatt tttgaagaac tcagttctca
    18961 atatcctgct tcaaatgaag gaaatgccgt ctgaaaatta aacacggttt cagacggcat
    19021 tttgattgtt ggatttccaa tccaacctac gcttgctgaa agatttcaaa caacataaat
    19081 atcaaataac gcttgcacga tttatatcca aataatcaat acctagctca tcaaatctcg
    19141 tttccaagtc ttctactgaa tgagtattca agaaaagtct ttctggctgg gtaattggca
    19201 ataaccagaa aaatcggaca ttatccatat attccaattc ttgcccataa ggataaggca
    19261 gagaaatcag aaaatgctgg aaggatgatt gctcaaccca cggtctgccg atattgaccg
    19321 ttttccctaa ttgaaatcga tcgggataat gcatacttgc agatgccagc attgccaagg
    19381 tctcaatatg ttcaggtgtt tcaaatgggc tgatgataaa aaactcctgc tctaaaaatt
    19441 gacctattcc agagctgaca taaacccaag gctcatcttc atgattagga atcacttgga
    19501 aaacttggaa atcgggaagt tcttcaacaa tccttcctaa agcccaagta aatcctttaa
    19561 tatcatgatg tttccaaaaa ttttgcaaat gagataaaac agtttggtta tagtccatgc
    19621 tttttagcct gttttcaaag gtcgcctgaa acctgaaaca aggtttttca gacggcattg
    19681 accgtttgaa gaaggtattt accaagcaaa cggtttccga ttcatatccg aaaggttgtc
    19741 aacttcatta tccagcaaga actgctcaaa agcattccaa cccttttttt ccaccaattc
    19801 tgcttcctgt ttatacaacg ggacaagcaa agggaaaacg atattgtagt gttcgccata
    19861 acagacctga aaatcatcgt cgaaataaaa tggggcggaa acatacagtg catccatttt
    19921 gctaccttcg ataattaccc tgggtaattg aataatttca cctcttaaaa taggttgtct
    19981 attgtcaatc aaatattcag ccactcctga tagaaaagct gcaatatttt ctttattcca
    20041 ttcttcagaa caggtaaaaa ttaattcaaa cctactctta tagttcaagt catatcgatt
    20101 caagcctaaa gtagaaaaag tagttacccc tttatatggt tgtgatggga agacggaaac
    20161 gctgagatga taacgtcgat ccaagcattt tataccgctt tcgatttcac ccaaataatg
    20221 ttctaaatgt tcaactataa tcattttttc ttaaagattt catccctatc ccggcaagac
    20281 gtaggctgtt ttgggctcca ataccgactt ttttattgac ggaaatgccg tctgaaaaat
    20341 aaagcggcat cttgattttg ccgtctaagg actttgcatc cattcctctt tgctgattcc
    20401 aaattcaaat tcagcctgtt caaatgccga atctaatgtg tcatgataag tatccgtttg
    20461 ttcctgaccg gtctcatcca aataaaacaa ataaaatccc gggtcatttt catattgaac
    20521 aatacttaaa gcaacaggtt tgggaagtat ccccatcggg gtacgatgaa tcgttctaat
    20581 aggaaaatct ttattttcat ctaagatgac tttgaataat tcttttacac tcatcattct
    20641 tcaatcccga ataattgtta ccgcactatt ttctattaca cgtccattag gtttgtcata
    20701 tgattcaaaa tgaccatgat gcgtagatga atttgtttca tgataaccat atcgtacctg
    20761 ccgcattcca tcttgtgata catatcgacc atttggatat gacttatagt tttcccctag
    20821 ccatttctca gctgcattta aaaaattaga ttcagataca gttcctgcat ggtattcggg
    20881 agctcttttg ggaggacaag aattatgaac ccaaacccct tccgtttccg cctgattacc
    20941 cttaacgaag taagtatgcc aatcggcaac ggtcagattg taggctttga gcggctgctg
    21001 tttgagagta atgttttgaa ccgtctgttt tgcaccgctt tcggaaagca gggtgtcgcc
    21061 ttttttcaga cgacctgcct gtatccattt tccttgactg taaaacgggt ggattttatt
    21121 ggaaacaagg gtttggctgt tgccgatgcc gtctgaaact tcaatgtaaa cggtttcccg
    21181 atacggattg ccgtatcggg cggtaacggg tttgtatcct gtttctccgc ttgcctcgtc
    21241 cttggaaagg acgcggtctc cggcttgaat atgggcgatg gctttgtagc cgtctgccgt
    21301 tttgaccaag gtgctgccgt ggaaagagca ggtgtaggat ttttgaagaa ctcagttctc
    21361 aatatcctat ttcaaatgaa ggaaatgccg tctgaaaatt aaacacggtt tcagacggca
    21421 ttttgattgc cgggttttgc tattttttgt tgtaataatc aaatcgcacg ttgactatgt
    21481 ctatctcggt aaaaatataa cggagcatta ctctgaacct ttcataacgc tcatcaattt
    21541 tgacactttt aggcaaccaa ggggaagatt taattgtaaa aagtttccaa tttggaacca
    21601 ttaaaaactc aataatggta ccgattccaa tcacgatatc ccttggtata tccatcggat
    21661 aaggatattt tctcctaacc tcgattaaag cattctccaa tttccaatat tcttcatcat
    21721 cccacacccc gtcatcatac catttgccaa taaatgaatt ttcgtcatac tcttcaaaac
    21781 aagggatgtt tcttctaaaa tccttgaact cgcacataat aattaatctc caatacgatt
    21841 taggttttta tcaaatgtac cgtttcttgt ttcttttctg taatgttatt catcgtagta
    21901 aggttctgtc gaataattgt ctttgccccc ggcaatgata gtaacaattt tcccttttgc
    21961 ttcccaagct tgtactccta tttcatcaaa ctcatagaca tatgtcggat aagattcatt
    22021 tgataaataa tatttatcaa caccgtatga tttagggtga tggaaaagct gtttaaaatc
    22081 ttcaaaattc agacctatta tattaacgcc cataaaatat agctcctgat aacaaaatat
    22141 cgaaataatt ttgttttttt cgacggaaat gagtaaattt gagtcgggag attcataata
    22201 ttctgttcca aactcatcag gaggttcata cataaaagtt tccagtatgt ttttgtactg
    22261 tgttatatca gcaccaaaac ggaatattcc tacagaagta aaaggtaaaa attcgggagt
    22321 tttaacgacc gcgtcgacca tgctcttctc cttttgcttt tcgattggca ttttttgtaa
    22381 tatttttgat tttttgctca atctttaagc gttcattttt gggcattccg ggaataattt
    22441 tattttttaa ttcagcaatt cttgattccg ctgatatttg acttcgaccg tcgtctccat
    22501 gtttttcatt cttggagctt cctgttcttt tgggcggaca cgcattatga acccaaactc
    22561 cttccgtttc cgcccgattg cctttgacaa agtaggtatg ccaatcggca acggtcagat
    22621 tgtaggcttt gagcggtttt ggtttgacaa cgatgttgcg gacggtttgg gttttgccgc
    22681 tttcggataa cagcctgatt cccgctttca aatcttccgt cttaatccat ttgccgcccg
    22741 aataaaacga gtggatgcgg ttggaaatca gggtttggct gttgccgatg ccgtctgaaa
    22801 gccggatatc gcttcagacg gcattttgat tgccaggttt tgctattttt tgttgtaata
    22861 atcaaatcgc acgttgacta tgtctttctc ggtaaaaata taacggagca ttgttttaag
    22921 cctttcataa cgttcgttaa ttcccacgct atcaggtagc caaggggaag ctttaatttc
    22981 aaaaagtttc caatttggaa ccattaagaa atcaataatg gtaccgattc caatgacaac
    23041 atatcttggt atgtccatcg gataaggata tttttttcta acctcgatta aattattctc
    23101 caacttccaa tattcttcat catcccacac cccgtcatca taccatttgc caataaatga
    23161 attttcgtca tacccctcaa aataaggaac gtttcttata atatccttga actcacacat
    23221 aataatgtat ctccaatata attaaacttt tcatctcaat ctacctttac tatgttgtat
    23281 tggaaagtaa aaaaatttcc agtcatctac atctagatca gtaaaaatat aacggagcat
    23341 tactctgaac ctttcataac gctcattaat tttgacactt ttaggcaacc aaggggaagc
    23401 tttaatttca aaaagtttcc aattttgaac cattaaaaaa tcaataatgg taccgattcc
    23461 aatcacgatg tcccttggta tatccatcgg ataaggatat ttttttctaa cctcgattaa
    23521 agcattctcc aatttccaat attcttcatc atcccacacc ccgtcatcat accatttgcc
    23581 aataaatgaa ttttcgtcat actcttcaaa acaagggatg tttcttctaa aatccttgaa
    23641 ctcgcacata ataattaatc tccaatacga tttaggtttt tatcaaatgt accgtttctt
    23701 gtttcttttc tgttcagatt tttgggtgaa gatgcttctt tccaagcccc tccattatgt
    23761 gaatctacat cgcgtgatat ataactcttt ccttttttaa aaatagcagc atcatttctc
    23821 gttctttctt ttatttttct atatcccaat ttctttgctg ctgcatatgc ttctgaatca
    23881 ttcccatata cgggggtaga tggtgttttt cttggcggac acgcattatg aacccaaacc
    23941 ccttccgttt ccgcctgact gcccttgacg aagtaggtat gccaatcggc gacggtcaga
    24001 ttgtaggctt tgagcggctg ctgtttgaag gtaatgtttt gaaccgtctg ttttgcgccg
    24061 ctttcggaaa gcagggtgtc gccttttttc agacgacctg cctgtatcca ttttccttga
    24121 ctgtaaaacg ggtggatttt attggaaatc agggtttggt tgttgccgat gccgtctgaa
    24181 atttcaatgt aaacggtttc ttgatacgga ttgccgtatc gggcggtaac gggtttgtat
    24241 cccgtttttc cgcttgcctc gtccttggcg aagacgcggt cgccggttcg gatacgggca
    24301 atggctttgt agccgtctgc cgttttgacc aaggtgctgc cgtggaagga gcaggtgtag
    24361 gatttttgaa gaactcagtt ctcaatatcc tatttcaaat gaaggaaatg ccgtctgaaa
    24421 attaaacacg gtttcagaag acattgtgat tgttggtttt ttaacctacg cttgcgaaat
    24481 taattccttt ctcctgaata ctgcaccatt tatttggttt aactccatag aagaatgatt
    24541 agaataaata cattcaaagt cagcttcatc aaaatattct ccacacatag accataactc
    24601 tgtaatcaaa tattccatat cttcatggtc ttctgtgatg gcttctcttg ataaataatt
    24661 tttgattttt aaaaaccttc ttccttcctc gtaatctacg gtaattaacc tgatatctga
    24721 gtgtatcatg cccagcattg ctatattcat accgactcgc agccagcttg gtaatatatt
    24781 cataactatt gcaccttttt aatggtttta gggttagccg gaacaatgtg aactccattt
    24841 ttacctgaat gaatcgtacc aaaattggta cttaatcctg atttcccatc gctgcctata
    24901 ggatacccaa aatcaacaac aggatttcct cttgctcctt tagaaataac tggataagca
    24961 cctgaatgta ttccgttcaa caattcttga ggattaatgt tttgatttaa agtactctta
    25021 ccttcaatgt agtttctatg tcctgaaata tgtttccctt gagctccatc atgaatttta
    25081 gtcccaatag attttgcttt aaaatcaaca ttgcgggttt gaaacatttc tccatctaca
    25141 gactgagata atcttgaagc agtgttatgc ttgtaggagt ctgagaaatc cccactaacc
    25201 gcagccttcc ccggttttgc cgcctttgcc agcttcgcga ctttggctgc tgcggcaacg
    25261 ttgaagacgg cttcgacggt ttcggcggca ttggggtttt cctgtatcca ccggtcaacg
    25321 gcttcgcgcg tatttttttc aaagcccgcc acgctgccca agccgccgat gacggcgaat
    25381 ttgccctcgg cgggcaaggg ggcgatgttg cgcattgcgg ctttgtctat ggcatagcgc
    25441 gttccgtaca gtatgtcgcc tatgcctaag gcttcgcccg cgctgataaa ggggttgagc
    25501 gcgccggcgg cgacgccgtt gataaactcc atgctgttgc cccagcggtc gagcttggca
    25561 ttgtgctcga acatttttct gttggcttca tcggcgcggt cggagaaatt gctgccgagg
    25621 ttgttgtagt tgtcggatat gcgttgccgg atgctgcggg tgtcggtcgg attgagtttg
    25681 atactgcggg ctgtgccgtt gacgtgatag gtgtattcgt ctcgtgcgcc cgtaggtttg
    25741 gggtaattgc cgcccttcgg gccgtcgtag gcatcggcgg gatgatgttc gtgtccttcc
    25801 cagttgagcc ggtatacggt aaagccttcg tcaacgttgc cttgttcttt gcttgcgctg
    25861 tcggcggcgt ggttgtcgaa gggggcgtgt tcttcgt
//
LOCUS       DAXIDM010000016        25558 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000016 DAXIDM010000000
VERSION     DAXIDM010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 25558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25558
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.016"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(400..2241)
                     /locus_tag="ACFOAE_000564"
     CDS             complement(400..2241)
                     /locus_tag="ACFOAE_000564"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0047134 - protein-disulfide reductase
                     (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HFC6884110.1"
                     /translation="MRTNYLSETDSIMKKLICLFAVFLMLCGRAFALDANDLLPPEKA
                     FVPELAVVDDGVNVRFRIADGYYMYQAKIVGKTDPADLLGQPSFSKGEEKEDEFFGRQ
                     TVYHHEAQVAFPYAKAVGEPYKLVLTYQGCAEAGVCYPPVDTEFDISGNGTYHPQTDE
                     PASAKDRFLQPSSQNGSGALPPPKGDEGGDSRFKLSWDTLNANLLAFFLAGLGLSFTA
                     CMYPLLPIVSSIVVGDKKAGKARAFVLSVVYVQGLALTYTLVGIVAGLTGALLTVWLQ
                     QAWVVLAASALMVVLALSMFGLFNIQLPNAVQSYFQNQSSRLSGGKIVSVFIMGILSA
                     LIVGPCVAPPLAFALGYIGQTGDAVLGGLALYTLALGTGVPLIAIGTFGGHILPKAGD
                     WMNAVKYAFGFILLAVAVYLATPHLPYYLVVALYTLLMLVPACMLLVNGRRQKRRPKA
                     VAFALGGILLIGGAWFGWQGANGKTTALHHFLTLNPPAEAGKSSEHGKMFADTAALKA
                     AMDTALKEHPDKPVVLDFYADWCISCKEMAAYTLNQPEVHQAVDMERFFQIDVTANTP
                     EHQALLKEYGLFGPPGVFVVRSDGSRSEPLLGFVKADKFIEWYEQNR"
     gene            2332..2802
                     /locus_tag="ACFOAE_000565"
     CDS             2332..2802
                     /locus_tag="ACFOAE_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1841 family protein"
                     /protein_id="HFC6884111.1"
                     /translation="MYDVNTHDVRRFFARVWQQRLNPLQLSALEQKALRIVEAHPEYH
                     RYLERIEDHLDTDWLPENGESNPFLHMSLHLSVQEQAGIDQPHGIRAIHDTLCAKRGW
                     LEAEHEMMEALAETLWTAQRYGTGLDVNFYMTRLRKLIGLGAEDQARLNPHEIA"
     gene            complement(2875..3687)
                     /gene="hpnC"
                     /locus_tag="ACFOAE_000566"
     CDS             complement(2875..3687)
                     /gene="hpnC"
                     /locus_tag="ACFOAE_000566"
                     /EC_number="2.5.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="squalene synthase HpnC"
                     /protein_id="HFC6884112.1"
                     /translation="MSVGHYENFPVGSLILPRRLRKPVHAVYAFARTADDMADEGSMP
                     SEARLAGLDALRRELDVLASGGRSAHPLIARLDAEAVVPFGLDLQPFYDLLSAFSQDV
                     VKTRYGNFGELADYCRRSANPVGRIMLALYGKTDAVCVAQSDGICTALQLVNFWQDVA
                     VDWQKGRVYIPQDDLLKFGVSEGQIAEGRADAAFQRLMAYECRRAFRMLKAGSPLARE
                     LKGRIGLELRMIVLGAQLILQKLDACRYDVFAQRPVLDKKDWLIMLKKALWK"
     gene            complement(3774..4256)
                     /locus_tag="ACFOAE_000567"
     CDS             complement(3774..4256)
                     /locus_tag="ACFOAE_000567"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC6884113.1"
                     /translation="MAIVKNSVVSLHYEMYDANNQLLDKTEEPIAYLHGGYDGIFPLV
                     EEALHGKDAGDTVDVALSPDDAFGEQDPELVRIEDAGVFPVEVEVGMMFEADDPETGD
                     VVVYRVTDVADGKAVVDGNHPLAGMKIRFKATVESVRDASDEEIAHGHVHGPHGHHHH
                     "
     gene            4729..5085
                     /locus_tag="ACFOAE_000568"
     CDS             4729..5085
                     /locus_tag="ACFOAE_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884114.1"
                     /translation="MKKSLFAAALLSLVLAACGGEKAAEAPAAEAPAAEAPATEAPAA
                     EAPAAEAPAAEAPATEAPAAEAPAAEAPAAEAPATEAPAAEAPAAEAAATEAPAAEAA
                     ASEAPAAEAPAAEAAK"
     gene            5195..6562
                     /locus_tag="ACFOAE_000569"
     CDS             5195..6562
                     /locus_tag="ACFOAE_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HFC6884115.1"
                     /translation="MPDLHTEFSRLLPADEIAELSPTLLKDQRNRFTSAPDIILQPRS
                     VESVQTIMRFCYEHRIPVTPQGGNTGLCGAAVSENGVLLNLSKLNRIRSINLSDNCIT
                     VEAGSVLQTVQQAAEASNRLFPLSLASEGSCQIGGNIACNAGGLNVLRYGTMRDLVIG
                     LEVVLPNGELVSHLHPLHKNTTGYDLRHLFIGSEGTLGIITAATLKLFARPSDKATAW
                     VGIPDIESAVRLLTETQAHFAERLCSFELIGRFAAELSSEFSKFPLPTHSEWHILLEL
                     TDSLPDSNLDDRLVEFLYKKGFTDSVLAQSEQERIHMWALRENISASQRKLGTSIKHD
                     IAIPIGRVADFVRRCAKDLEQNFKGIQIVCFGHLGDGSLHYNTFLPEILSNEVYRYEN
                     DINDAVYRNVLACNGTIAAEHGIGIIKKQWLDKVRTPAEIALMKSIKQHLDPYNIMNP
                     GKLLP"
     gene            complement(6743..8911)
                     /locus_tag="ACFOAE_000570"
     CDS             complement(6743..8911)
                     /locus_tag="ACFOAE_000570"
                     /inference="COORDINATES: protein motif:HMM:TIGR01414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HFC6884116.1"
                     /translation="MAVDYVYDKTKLTDDEITRLKKLRDRNSEYWKDDLFRLDLPKDL
                     GNDFDGKPILRHDIEGAATGNFVYPILYDKSFSSLNNINPDKKISFFDSPYTPGYTAA
                     FVQGFGVKERNGNTEEEAKQYINELRAILKKESTTYWKYFFYAENGEGGDLTHQEYGN
                     GIFDSYGDVNHSNINSEILAVGNVADLYYKQYIRRSHVYLDGAMLSLPFPGLKVSENS
                     HVIGQIIHLYELKLEDSLWEPRWDSDVSYLRLYNSHIRFNTKNESLVVGESRIRPTPD
                     NASSPEQYFKRAYGKDIGYQSGSPVTTCDYSGCRDGYSGNSSIHFAYDLSEREADKPV
                     LTLKSKVRGKTAIVFEEKALNNLKNLTYRQLIKTETDVEPDAFFLLEEYKKGRYRLFL
                     QQCPNGFCIGVEKLAIPIPTHLVASYAQQAQAANTLFALRLNDKNSDIFDRTLPRKGL
                     WLRLISGHLSQDVQGKTAPVEGNRKGIQLGGDVFSLQNHNYQLSVGLMGGQAEQRSTF
                     RNPDTDNLTTGNVKGFGAGVYATWHQLQDKQTGAYADSWVQYQRFRHRINTEDGTERF
                     TSKGITASIEAGYNALLAEHVTKKGNSLRVYLQPQAQLTYLGVNGKFSDSENAHVNLL
                     GSRQLQSRVGVQAKAQFAFTNGVTFQPFVSVNSIYQQKPFGVEMDGERRVINNKTAIE
                     SQLGVAVKIKSHLTLQATFNRQTGKHHQTKQGALNLQWTF"
     gene            complement(9396..9842)
                     /gene="smpB"
                     /locus_tag="ACFOAE_000571"
     CDS             complement(9396..9842)
                     /gene="smpB"
                     /locus_tag="ACFOAE_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFC6884117.1"
                     /translation="MAIANNKKAFHDFFIEDRIEAGLVLEGWEVKAIRAARVQLKESY
                     IYWKKDAFYLVGCHITALPTASTHIRPDAVRPRKLLLNQSEINKLIGKTERAGYTIVP
                     LDLHFSRGKIKMEIGLAKGKKQHDKRQSMKEADWKREKQRLIKHTR"
     gene            complement(9897..10907)
                     /gene="waaF"
                     /locus_tag="ACFOAE_000572"
     CDS             complement(9897..10907)
                     /gene="waaF"
                     /locus_tag="ACFOAE_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008920 - lipopolysaccharide
                     heptosyltransferase activity [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase II"
                     /protein_id="HFC6884118.1"
                     /translation="MSIKILIISPSWIGDCVMTQPLFRRLKELHPGCTIDVFAPKWSM
                     AVFERMPEVNEILENPFGHGALELKRRWRVGRDLGRRGYDQVIVLPGSLKSAVIALAT
                     GIGKRTGYVGESRYFLLNDIRRLDKERLPLMVDRYTALAHPSQEDFDGHSGFPEFSID
                     ERRREISVETFGLDIGKPVLAFCPGAEFGPAKRWPTKHFAELGKHYSAAGWQVWLFGS
                     QKDDEIAEEINRLSDGICVNLCGKTDLSQAMDLLSLADTVVCNDSGLMHLAAALGRKV
                     VAVYGSSSPTHTPPLSDRAKIVSLHLECSPCFKRECPLGHTDCLNRLYPEKIVQAVEE
                     AV"
     gene            complement(11038..11113)
                     /locus_tag="ACFOAE_000573"
     tRNA            complement(11038..11113)
                     /locus_tag="ACFOAE_000573"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11078..11080),aa:Asn,seq:gtt)
     gene            complement(11304..12056)
                     /locus_tag="ACFOAE_000574"
     CDS             complement(11304..12056)
                     /locus_tag="ACFOAE_000574"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFC6884119.1"
                     /translation="MITLPSLNNLPSKWDEIRYWLETRVFECGVMPHPNLTECEAGQF
                     DRDFWDNIGCAPEEYVRIRRAIRLLEARYPDSLNELVCAAIATPLGEMLAVFGNKGLC
                     LLEFVGQKHLEQEIAAVQKALRGRFVFREDERTQLLRQELDLYFKGRLKTFATPLEQI
                     GTEFQKQAWDALLAIPYGETRSYKEQAQRLGNPKAVRAVAAANGQNKVSILIPCHRVI
                     GSDGKLTGYAGGLNRKQFLLALERGEVQTALF"
     gene            12406..12753
                     /locus_tag="ACFOAE_000575"
                     /pseudo
     CDS             12406..12753
                     /locus_tag="ACFOAE_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255955.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
     gene            complement(12742..13368)
                     /locus_tag="ACFOAE_000576"
                     /pseudo
     CDS             complement(12742..13368)
                     /locus_tag="ACFOAE_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751227.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            13388..13498
                     /locus_tag="ACFOAE_000577"
                     /pseudo
     CDS             13388..13498
                     /locus_tag="ACFOAE_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(13827..13988)
                     /locus_tag="ACFOAE_000578"
     CDS             complement(13827..13988)
                     /locus_tag="ACFOAE_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884120.1"
                     /translation="MPSEKKMGCRIWMSDHLIRPNVGLRYSGLNSNQYGVASPCRTIC
                     TVCGFVALS"
     gene            complement(13978..15123)
                     /gene="dapE"
                     /locus_tag="ACFOAE_000579"
     CDS             complement(13978..15123)
                     /gene="dapE"
                     /locus_tag="ACFOAE_000579"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HFC6884121.1"
                     /translation="MTETRSLELAKELIARPSVTPDDQNCQKLLAERLHKIGFAAEEL
                     HFGDTKNIWLRRGTKAPVVCFAGHTDVVPTGPVEKWDSPPFEPTERDGRLYGRGAADM
                     KTGIACFVTACERFVAEHPDHQGSIALLITSDEEGDALDGTTKVVDVLKARGELIDYC
                     IVGEPTAVDKLGDMIKNGRRGSLSGNLTVKGKQGHIAYPHLAINPVHTFAPALLELTQ
                     EVWDEGNEYFPPTSFQISNINGGTGATNVIPGELNVKFNFRFSTESTEAGLKQRVHTI
                     LDKHGVQYDLQWSCSGQPFLTHAGKLTDVARAAIAETCGVETELSTTGGTSDGRFIKA
                     IAKELIELGPSNATIHQINENVRLDDIPKLSAVYEGILARLLAGNAV"
     gene            complement(15223..15843)
                     /locus_tag="ACFOAE_000580"
     CDS             complement(15223..15843)
                     /locus_tag="ACFOAE_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFC6884122.1"
                     /translation="MLTPKSCDLFNIPFFQFSQLKKYQPESIPQIKADYKENWQIWQQ
                     LIQQVAAELGAPFAPPHIERWCNGWQVRAHFFAYFKYEQYKNSAAILSILLNRRRLSV
                     SLDWHCYKADVSPIALPDYNRWLDNFDTEKYASFDMWHGAESEYDDYRTVAQQNESDR
                     KLQNDEDFFCIGKHIERDDLGRQDVAKWIAETVEDLLPLYEACHGA"
     gene            complement(15877..16386)
                     /locus_tag="ACFOAE_000581"
     CDS             complement(15877..16386)
                     /locus_tag="ACFOAE_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HFC6884123.1"
                     /translation="MNPFETKSVTFAEPIEMLYACHGKVRRFCGQVAMLSDYIAENGC
                     NQIVLQTIRQIAQYFNVAAPLHHEDEEENFFPLLLQYAPQAQESVDELLRQHIGLHDN
                     WAAVSAEFAKLEADNAYVPDEEAFKRFVAGYDVHLAIEEPLFDMGNTFIPKEKLTEIG
                     EIMAARRRK"
     gene            complement(16481..17032)
                     /gene="azu"
                     /locus_tag="ACFOAE_000582"
     CDS             complement(16481..17032)
                     /gene="azu"
                     /locus_tag="ACFOAE_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="azurin"
                     /protein_id="HFC6884124.1"
                     /translation="MKAYLALISAAVIGLAACSQEPAAPAAEATPAAEAPASEAPAAE
                     AAPADAAEAPAAGNCAATVESNDNMQFNTKDIQVSKACKEFTITLKHTGTQPKASMGH
                     NLVIAKAEDMDGVFKDGVGAADTDYVKPDDARVVAHTKLIGGGEESSLTLDPAKLADG
                     DYKFACTFPGHGALMNGKVTLVD"
     gene            complement(17314..17736)
                     /locus_tag="ACFOAE_000583"
     CDS             complement(17314..17736)
                     /locus_tag="ACFOAE_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DciA family protein"
                     /protein_id="HFC6884125.1"
                     /translation="MNLEQLGRRDALLSGLLKQAGQWRRLDAAVKKLLPANLHPHFQT
                     ACIEDGRLVLLAANNMAASRLKMIAPSVLPQLAGLDVSIRSVSVRLVPKPEKPPKTNT
                     LHLSKAALESFGSAAAKLEKRHPELAAVLAELVRKHGA"
     gene            17867..20617
                     /gene="secA"
                     /locus_tag="ACFOAE_000584"
     CDS             17867..20617
                     /gene="secA"
                     /locus_tag="ACFOAE_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFC6884126.1"
                     /translation="MLTNIAKKIFGSRNDRLLKQYRKSVARINALEEQMQALSDADLQ
                     AKTAEFKQRLADGQTLDGILPEAFAVCREASRRTLGMRHFDVQLIGGMVLHDGKIAEM
                     RTGEGKTLVATLAVYLNALAGKGVHVVTVNDYLASRDAGIMEPLYNFLGLTVGVIISD
                     MQPFDRQNAYAADITYGTNNEFGFDYLRDNMVTDQYDKVQRELNFAVVDEVDSILIDE
                     ARTPLIISGQADDNIQLYQIMNTVPPHLVRQETEEGEGDYWIDEKAHQVILSEAGHEH
                     AEQILTQMGLLAENDSLYSAANIALMHHLMAALRAHSLFHKDQHYVIQDGEIVIVDEF
                     TGRLMSGRRWSEGLHQAVEAKEGVEIKRENQTLASITFQNYFRLYTKLSGMTGTADTE
                     AFEFQSIYNLETVIIPTNRPVQRKDFNDQIFRSAEEKFEAVVKDIEECHKRGQPVLVG
                     TTSIENSELVSHLLQKAGLPHNVLNAKEHEREALIVAQAGKVGAITVATNMAGRGTDI
                     VLGGNLKHQTDAIRADETLSDEEKQAQIAALENGWQAEHDKVMEAGGLHIIGTERHES
                     RRIDNQLRGRSGRQGDPGSSRFYLSFEDPLLRLFALDRAAAILNRLAPERGVAIEHNL
                     LTRQIEGAQRKVEGRNFDMRKQVLEYDDVANEQRKVIYSQRNEILTSKDISDLMQEIR
                     SDVVSDLVDTYMPPDSMEEQWDIPTLENRLAAEFRLHEDIQSWLKADNAIDGQDIKER
                     LIERIENEYAAKTELVGKQAMADFERNVMLQVIDNQWREHLAAMDYLRQGIHLRSYAQ
                     KNPKQEYKREAFTMFQDLWNGIKFHIASLLTSVQIEQNPVAVVEEQPIGNIQSIHSES
                     PDMEELLGQSQTDLVTEAFNPDGTDFSPEALEARGQIVHRNDPCPCGSGLKYKQCHGK
                     LA"
     gene            20763..22535
                     /gene="dnaG"
                     /locus_tag="ACFOAE_000585"
     CDS             20763..22535
                     /gene="dnaG"
                     /locus_tag="ACFOAE_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFC6884127.1"
                     /translation="MIPSDFIDELLAKTDIVDIIDEQVPLKKGGANYMACCPFHKEKT
                     PSFSVSPTKQFYHCFSCGAHGSAIGFVMEHQGLSFPEAVQFLADRVGMIVPKVRGQND
                     NPEVRAERKKKQQTLEETTAAAADFYAQQLKFNPAAKAYLDKRGLSAEVIAHYGLGYA
                     PDGWQPLAQVFQPYPNTALVDTGMVIDNEGRYYDRFRHRIMFPIRNPRGQVIGFGGRV
                     LDDSKPKYLNSPDTPLFDKGKNLYGLYEGRAAVKEAERILVVEGYMDVVALAQFGVGY
                     GVAALGTATTAEHVKILMRQADSIYFCFDGDSAGRKAAWRALENALPQLKDDKSLHFL
                     FLPEEHDPDSYIRAYGKAQFEDALLNQSKPLSEYFWEHLSDGIHLNTQEGKAELVKTS
                     SPLLAQITAPALAYLLKQRLSELVGIDPDNLAQLLGLEAPKRHVKQKNYKLPPISVKQ
                     PVMLTLVQRQIRSLLINPDWAAYIDLPDYLALDGDFACLANLAESIKNHAAVPETAQV
                     LEYMRGSPYEETITRIFHSTHQSEEMNSSSEEDCENFQIGMKKLLNELKYSQIEALKQ
                     KSLQSGLNESEKKLLLSLLTAKQN"
     gene            22722..24650
                     /gene="rpoD"
                     /locus_tag="ACFOAE_000586"
     CDS             22722..24650
                     /gene="rpoD"
                     /locus_tag="ACFOAE_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFC6884128.1"
                     /translation="MSRNQNHEEYQDDTRPLSIEEQRARLRQLIIMGKERGYITYSEI
                     NDALPDDMSDADQIDNIVSMISGLGIQVTEHAPDAEDILLSDNAAVTDDDAVEEAEAA
                     LSSADSEFGRTTDPVRMYMREMGQVDLLTREDEIIIAKKIENALKNMVQAISACPGSI
                     AEILELIEKIRKDEIRVDEVVEAIIDPNEVLLNELGLGHLETTAPEKPSNDNSDENED
                     DEESEEDADEISAANLAELKQKVIGHFAQIEKDYKKMIGRLEKHHSRHKDYLAYRDAI
                     ANKLLEVRFATRQIDSLSSSLRGKVENIRKLEREIRDICLDRVHMERDYFIQNFLPEI
                     TNLEWIEEEIAKGRVWSDALDRFRHAILEKQTELADMEKETRISIEELKEINKNMVSS
                     EKETAAAKQEMIQANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYK
                     FSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQHLQETGEEPDSAKLA
                     ELMQMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDANNVAPADAAMYTSLHE
                     VTKEILESLTPREAKVLRMRFGIDMNTDHTLEEVGRQFDVTRERIRQIEAKALRKLRH
                     PTRSDRLRSFLDSEDSKL"
     gene            24797..>25558
                     /locus_tag="ACFOAE_000587"
     CDS             24797..>25558
                     /locus_tag="ACFOAE_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC6884129.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQKTR
                     YLRDHRGRPAYPLLSMFKAILPGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNRLAQDDTLSELLELINRQLTEKGLKIEKASAAVVDATIIQTAGSKQRQAIE
                     VDEEGQINGQTTPSKDSDARWIKKNGLYKLGYKQHTRTDAEGYIEKLHITPANTHECN
                     HLLPLLEGITEGTTIYADKGYDSAENRQHLEEHQLL"
BASE COUNT         6667 a         7156 c         5900 g         5835 t
ORIGIN      
        1 gcttcgtcgc cttgtcctga tttttgttaa tccactatat ccggctttcc atgcttaaac
       61 agcactgcct cttttcagac attgacggtt gcagccgact acctgaacct taatgattga
      121 ctatttttta atcatgttat tattttccat aaaatacatg acattaagat gtttttccac
      181 aaaagataca cacaccggca aacaccggct gtgtttatct tttcttatgc ctatttttta
      241 atcatcgtat ttttatcttt taatttcaat acgcaaacta acttatacac acggttttca
      301 catctttgga ctgcttccgt gtgtatagcg gatattgccg ttttcctttc tgacaaaaat
      361 gccgtctgag aacttcagac ggcatttgaa acatcggaat cagcggtttt gttcatacca
      421 ctcgataaac ttgtctgctt tgacaaaacc cagcagcggc tcgctgcggc tgccgtcgga
      481 gcggacgaca aacacgcccg gcggcccgaa cagaccgtat tctttcaaca acgcctgatg
      541 ttcgggcgtg ttggcggtta cgtcgatttg gaaaaagcgt tccatatcga ctgcctgatg
      601 cacttccggc tgattaagcg tgtaagccgc catttctttg caggaaatgc accagtcggc
      661 ataaaaatcc aaaacgacgg gtttgtcggg atgttctttc aacgccgtat ccatcgctgc
      721 cttcagcgcg gcagtatcgg caaacatttt tccgtgttcc gaagatttgc ctgcttcggc
      781 cggcggattg agggtcagga aatggtgcag cgcggtcgtt ttgccgtttg cgccctgcca
      841 gccgaaccac gcgccgccta tcagcaatat gccgcccaat gcgaatgcca cagctttcgg
      901 acggcgtttc tgcctgcgtc cgttgaccag cagcatacag gcaggaacca gcatcagcag
      961 cgtgtacagc gcgacgacga gataataggg caagtgcggc gtggcgaggt aaacggcgac
     1021 ggcaagcagg ataaagccga aagcgtattt gacggcattc atccaatcgc ctgccttagg
     1081 caggatatgc ccgccgaacg tgccgatggc aatcagcgga acgccggtgc ccaacgccaa
     1141 agtgtaaagt gccaaaccgc ctaaaaccgc atcgcccgtc tgaccgatgt agcccaaagc
     1201 aaatgccagc ggcggggcga cgcacggccc gacaatcagc gcggacaata tgcccataat
     1261 aaagacggaa acgattttac cgcctgaaag cctgctgctt tgattctgaa aatacgactg
     1321 cacggcgttg ggaagctgga tgttgaacag cccgaacata gacagtgcca agacgaccat
     1381 caaagccgat gccgccaaca cgacccaagc ctgctgcaac catacggtca gcagcgcgcc
     1441 cgtcagtccg gcaacaatgc cgaccagcgt ataagtcaga gccaaaccct gaacataaac
     1501 gacggacagc acaaacgccc gcgccttgcc cgcctttttg tcgccgacca caatactgga
     1561 aacaatcggc aacaggggat acatacaggc ggtaaaactc agacccaaac cggcgagaaa
     1621 aaacgccaaa agattggcgt tgagcgtatc ccaagacagc ttgaaacggc tgtcgccgcc
     1681 ctcatccccc ttcgggggcg gcagcgcccc gctgccgttt tgagaggaag gctgcaaaaa
     1741 gcgatctttg gcggatgccg gttcgtcggt ttgcggatgg taagtgccgt tgccggaaat
     1801 atcaaactcg gtatccacgg gcggatagca cacgccggct tcggcacagc cctgataggt
     1861 caaaaccaat ttatacggtt cgccgacagc ctttgcataa ggaaaggcaa cctgcgcttc
     1921 gtgatggtaa accgtctgcc tgccgaaaaa ctcgtcttcc ttctcttcgc ccttgctgaa
     1981 agaaggctgt cccaacaaat ccgccggatc ggtcttgccg acgattttcg cctgatacat
     2041 atagtatccg tcggcaatcc tgaaacggac gttcacaccg tcgtcgacaa cggcaagctc
     2101 cggcacgaat gccttttccg gcggcagcag atcgttcgca tccagcgcga aagctcgtcc
     2161 gcacaacatc aaaaatacgg cgaacaggca aatcagtttt ttcataatcg aatccgtttc
     2221 agacaaataa tttgtccgca ttataaatgg taaggttgac ggtgggattt aatttatgta
     2281 aaacccgcca ttatccgaac ctatttccat aaacatctta ccgaacccgc catgtacgat
     2341 gtcaataccc acgatgtccg ccgctttttc gcccgcgtgt ggcagcagcg gctcaatccg
     2401 ctgcaactga gcgcactgga acagaaagcc ctccgcattg tcgaagccca tcccgaatac
     2461 caccgctatc tcgaacgcat cgaagaccat ctggacaccg actggctgcc cgaaaacggc
     2521 gaaagcaacc ccttcctgca tatgtcgctg catctgtccg tccaagaaca ggcgggcata
     2581 gaccagccgc acggcatacg cgcaatccac gacaccctgt gcgccaaacg cggctggctg
     2641 gaagccgaac acgaaatgat ggaggcactg gcggaaacac tgtggacggc gcaacgctac
     2701 ggcaccggtt tggatgtcaa tttctacatg acccgactgc gcaaactcat cggcttgggt
     2761 gcagaagatc aagccaggtt gaacccgcat gaaatcgcct gaccatacca accgcctgca
     2821 aaatgccgtc tgaagcggaa caaccccttt cagacggcat tcattttccc ccaatcattt
     2881 ccacaacgcc tttttcagca taatcaacca atccttctta tccaaaacgg ggcgttgtgc
     2941 aaacacatcg tatcggcacg cgtccagttt ctgcaaaatc aactgcgccc ccaacacaat
     3001 catacggagt tccaaaccga tacgcccttt caattcgcgc gctaaaggcg aacccgcctt
     3061 cagcatacga aatgcgcgcc ggcactcata cgccatcagc cgctgaaacg ccgcatccgc
     3121 cctaccctcc gcaatctgtc cttcggaaac accgaatttc aacaaatcgt cctgcggaat
     3181 ataaaccctg cccttttgcc aatccacagc cacatcctgc caaaaattca ccagttgcaa
     3241 agccgtacag atgccgtcgc tttgcgccac gcacaccgca tccgttttcc cgtacaaagc
     3301 cagcataatg cgtccgacag ggttggcgga acgccgacaa taatcggcca gctcgccgaa
     3361 atttccatac cttgttttaa ccacatcctg agaaaatgca gaaagcaaat cataaaacgg
     3421 ctgcaaatcc aaaccgaacg gcacaaccgc ctcggcatcc aatcgtgcaa tcaaaggatg
     3481 cgccgaccgg ccgcccgatg ccaacacgtc caactcgcgc cgcaaagcat ccaaccccgc
     3541 caacctggct tcagacggca tactgccctc gtccgccata tcgtccgccg tccgtgcaaa
     3601 cgcatacacc gcatgaaccg gcttcctcaa cctgcgcggc aaaatcagcg aaccgacggg
     3661 aaaattttca taatgcccaa ccgacatacc ttctccatcc atcaaacaaa atgccgtctg
     3721 aaatggaaca aacccttttc agacggcatc agatacctcc aagctgccgg caatcagtgg
     3781 tggtgatgac cgtgcggacc gtggacatga ccgtgtgcga tttcctcatc ggatgcatcg
     3841 cgcacacttt caaccgtagc cttaaagcgg attttcatgc ctgccaaagg atggttgccg
     3901 tccaccaccg ccttaccgtc ggcaacatcg gttacacgat agacgacaac atcgccggtt
     3961 tcaggatcgt cggcttcaaa catcatgccg acttcgactt caacagggaa cacgcccgca
     4021 tcttcaatac ggaccaactc cggatcctgc tcgccgaacg catcgtcggg cgaaagcgcc
     4081 acatcgaccg tatcgccggc atccttaccg tgcaacgcct cttccaccaa agggaaaata
     4141 ccgtcgtaac cgccgtgcag atacgcaatc ggttcttcgg ttttgtccaa aagctgattg
     4201 ttggcatcat acatctcata atgcagcgaa accacggaat ttttcacgat agccatattt
     4261 gtcctttcag gaacagcaga ttgattacag gcgcattcta acacaaccgc cgcgccggcc
     4321 gattaccgtt aacctattca taaactgtac agcacatatt tcaatgtaaa tttttgttat
     4381 tttattgcgg tgtaactttt ttacaacatt cttaaaacca ttccgacctg tctgccgact
     4441 ttcccaatcc gccttaataa atcatacaag atactgaaat tatattaatc tctataatat
     4501 ttatccctat cgaattttta acagcaaaac cgttttacag gatttatcaa tccgcccgcc
     4561 agaaaacttt tcattcaaac ctttttccca tctgtacgac attgcaatcc cttattccat
     4621 agtgcataat tacgcaaatt cagcgatgaa tttccaaccc ggtttgtagt atggtcgata
     4681 aagacctatt tgtttcaata atttaaattg gttctaaagg ttactaaaat gaaaaaatcc
     4741 ctgtttgccg ctgctttgtt gtctttggtt ctggcagcct gcggcggtga aaaagccgct
     4801 gaagctcccg ctgctgaagc acctgccgcc gaagctcccg ctactgaagc acctgccgct
     4861 gaagctcccg ctgctgaagc acctgccgcc gaagctcctg ctactgaagc acctgccgcc
     4921 gaagctcccg ctgctgaagc acctgccgcc gaagctcctg ctactgaagc acctgccgcc
     4981 gaagctcccg ctgctgaagc tgccgctacc gaagcacctg ccgctgaagc tgccgcttct
     5041 gaggctcctg ccgctgaagc tcctgctgcc gaagctgcaa aataagcatt ttccgcttgc
     5101 aaaaaagcag gatacgttca gtatcctgct tttttgattt ttcagacggc atcagattcc
     5161 tttcctcaat cttctcccta cccttccgac aaacatgcct gaccttcata ccgaattttc
     5221 ccgactcctg ccggcagatg aaattgccga actttctccg acgcttttaa aagaccagcg
     5281 caaccgcttt acgtctgcac cagacatcat tttgcagccg cgcagcgttg aaagcgtgca
     5341 aaccattatg cgtttttgtt acgaacaccg tattccggtt acgccgcaag gcggcaatac
     5401 cggtttgtgc ggcgcggcag tatcggaaaa cggcgtattg ctgaaccttt ccaaactcaa
     5461 ccgcatccgc agcatcaatt tgtcagacaa ctgcataacc gtcgaagcag gttccgtact
     5521 ccaaaccgtc caacaggcag ccgaagcctc aaacaggctg ttcccactca gtctcgccag
     5581 cgaaggctcc tgtcaaatcg gcggcaacat cgcctgcaat gccggaggtt tgaacgtatt
     5641 gcgttacggc acgatgcgcg acctggttat cggtttggaa gtcgtcctcc ccaacggcga
     5701 gctggtttcc catctccatc ccctgcataa aaacaccacc ggctacgacc tgcgccatct
     5761 gtttatcggc agcgaaggca cactgggcat catcactgcc gccacgctca agctttttgc
     5821 ccgtccctcg gacaaggcaa cggcatgggt cggcataccc gacatcgaat ccgccgtccg
     5881 cctgctgacc gaaacccaag ctcactttgc cgaacgccta tgcagttttg agctgatcgg
     5941 ccgttttgcc gccgagttgt cttccgaatt cagcaaattc cccctgccga cacattcaga
     6001 atggcatatt ttacttgagt tgaccgactc attacccgac agcaatcttg atgatcggct
     6061 tgtcgaattt ctttataaaa aaggatttac cgacagcgta ttggcacaaa gcgaacaaga
     6121 acgtatccat atgtgggcat tgcgcgaaaa catctccgcc tcccaacgca aactgggcac
     6181 cagcatcaaa cacgatattg ccattcctat cggacgcgtt gccgactttg tccgccggtg
     6241 cgccaaagat ttggaacaga attttaaagg catacaaatc gtctgcttcg gacatcttgg
     6301 cgacggcagc ctgcactaca atactttcct gcccgaaatc ctcagcaatg aagtctatcg
     6361 ttacgaaaac gacatcaacg acgcagttta tcgcaacgtt cttgcctgca acggcacgat
     6421 tgccgccgaa cacggcatag gtatcatcaa aaaacagtgg ctggacaaag tacgcacgcc
     6481 tgccgaaatc gccctgatga aaagcatcaa acaacacctt gatccatata acattatgaa
     6541 tccgggcaaa ctgcttccgt aaccggcatt tctgatttgc atacacaaca aagaaaggga
     6601 caatagatcc gattgtcggt tgagcgcgag ctcgtgagtg cggtaaaaaa ttggtggaaa
     6661 tgacacgaaa aatgaccgca tttttaaaat aaaaaaatcg gcagtgaatt tccctgccga
     6721 ttttattttg ttacaactta acttaaaacg tccactgcaa attcaacgca ccttgtttag
     6781 tttgatgatg tttgcctgtt tggcggttga atgtggcttg taaggttaag tgagatttga
     6841 ttttcactgc tacacctaat tggctctcaa ttgccgtctt attgtttatc actcgacgtt
     6901 ctccgtccat ttctaccccg aaaggttttt gttggtagat tgaattgacg gaaacaaatg
     6961 gttggaaagt gacgccatta gtgaaagcaa attgagcttt agcttgaacg cccactcggc
     7021 tttgtaattg gcgagagcca agtaaattca cgtgggcatt ttcgctatcg ctgaattttc
     7081 cgtttacccc caaataagtc aattgcgcct gtggttgtag gtaaacacga aggctgttgc
     7141 cctttttagt tacgtgttcc gccaataaag cgttgtaacc tgcttcaatt gaggcagtaa
     7201 taccttttga agtaaaacgt tctgtaccat cttcagtgtt gatacggtgg cggaaacgtt
     7261 gatattgtac ccagctatcc gcatacgcac ctgtctgttt gtcctgaagc tgatgccaag
     7321 tggcgtaaac gcctgcacca aagcctttca catttcccgt tgtaagattg tctgtatctg
     7381 ggttgcggaa agtactgcgt tgttctgctt gtccgcccat taagccaacg gaaagttgat
     7441 agttgtgatt ttgcaatgag aaaacatcgc caccaagttg tatgccttta cgatttcctt
     7501 ctactggtgc ggttttacct tgtacatctt ggcttaagtg accactaatt aaacgcaacc
     7561 acaagccttt gcgtggtaaa gtgcggtcaa aaatatcgct gtttttgtcg ttcaaacgca
     7621 aggcgaataa ggtattggcg gcttgagcct gttgtgcata ggaggcgaca agatgagttg
     7681 gaattggaat ggcgagtttt tctacaccga tacaaaaacc gtttggacat tgttgcaaaa
     7741 ataaacgata tctgcctttt ttatattctt ctaaaagaaa aaacgcatct ggttcaacat
     7801 cggtttccgt tttgatgagc tgtcggtaag tcaggttttt taaattgttt aaggcttttt
     7861 cttcaaaaac aatagccgtt ttccctctta ccttgctttt taacgttaat acgggcttgt
     7921 cagcctctct ttcgctcaaa tcataagcaa agtgaatact tgagttaccc gaataaccat
     7981 cacggcatcc cgagtaatca cacgtagtga ctggcgagcc actctgataa cctatatctt
     8041 tgccatatgc tcttttaaaa tattgttcgg gtgatgaggc attatcgggg gttggtctaa
     8101 tgcgactttc gcctacaaca aggctttcat tttttgtgtt aaaacgaata tgactattgt
     8161 ataaacgcaa ataactgaca tcagaatccc aacggggttc ccaaagagaa tcttctagtt
     8221 ttaattcgta gagatgaata atttgcccaa tgacatggga attttcggaa acttttaatc
     8281 cgggaaaagg gagagagagc atagctccat ccagatatac atgtgaacgt cttatgtact
     8341 gtttataata caaatccgca acattaccaa cagcaagaat ttcactgtta atattgctat
     8401 ggtttacgtc tccataagaa tcgaaaatac cattaccata ttcttgatgt gtgaggtcac
     8461 cgccttctcc attttctgcg taaaaaaaat atttccaata ggtagtactc tcttttttta
     8521 agattgctct aagttcatta atatattgtt tagcttcttc ttccgtattg ccatttcttt
     8581 ctttaacgcc aaatccctgc acgaaagcag ccgtgtagcc aggggtataa gggctgtcga
     8641 aaaaagagat ctttttgtca ggattaatat tatttaagct actaaaactc ttgtcataca
     8701 aaattggata cacgaaattt cctgttgccg ccccctcaat gtcatgacgg agaataggtt
     8761 ttccatcaaa atcatttccc agatcttttg gcaaatcaag cctgaacaga tcatctttcc
     8821 aatattcact atttctatcg cggagttttt ttaagcgggt aatttcatca tcagtgagct
     8881 tggttttgtc gtaaacgtaa tcaacagcca aaagcggaga ggtataaaga atagaaaaaa
     8941 atagacttat aataaatgat tttttaaact tctgcttgct tgcttgcttg cttgcttgct
     9001 tgcttgcttg cttcgagttt cataataaat tttcctttgt caagtaaaaa taaatggggc
     9061 gtgtatttta gcataaaact gaacaaaaaa tgtcatttag ctcaaatttt tctctattta
     9121 tttcttattt attaaaagta aacgtttgct ttttgctatt ttgtcaagcc agtttgaaaa
     9181 tgtgtataat tgccctcgtt atttacaaaa atttcaggaa aaatgaccgc actttaccct
     9241 tggttaatgc caatttatca tcaaattgct caaacctttg atgaaggttt ggggcatcat
     9301 gctgtgctga ttaaagcgga tgctggttta ggtgtagaac gtttacacat caggcggcag
     9361 ccttgcccat accgtctgaa gcactgtttc cacaatcagc gcgtatgctt aatcaaccgc
     9421 tgtttctcgc gtttccaatc cgcctctttc atactctgac gtttgtcgtg ctgtttctta
     9481 ccttttgcca aaccgatttc catcttgatt tttccgcgcg aaaaatgcaa atccagcggc
     9541 acgatggtgt agccggcacg ttcggttttg ccgattaatt tgttgatttc cgactggttc
     9601 aacaagagct tgcgcggacg tacggcatct ggtctaatgt gtgtcgaggc tgtgggcaaa
     9661 gccgtaatat ggcagccgac cagataaaac gcgtcttttt tccaatagat ataactctct
     9721 ttaagctgta cgcgcgcggc gcggattgct ttgacttccc agccttccaa gaccaaaccg
     9781 gcttcaatcc ggtcttcaat gaaaaaatcg tgaaatgctt ttttattgtt cgcaatagcc
     9841 ataaacatcc tatcaatatc cgccgtcaga cggcataaac ccgaaaacag aacccatcat
     9901 accgcctctt caaccgcctg cacaatcttc tcgggataca gcctgttgag gcagtcggta
     9961 tgccccagcg gacattcccg cttaaaacag ggcgaacatt ccaagtgcag gctgacgatt
    10021 ttcgccctgt cgctcaaagg cggcgtatgc gtcgggctgg aagaaccgta aaccgccacc
    10081 accttcctgc ccaatgccgc cgccaagtgc atcagcccgc tgtcgttgca tacgaccgtg
    10141 tccgccaacg acagcaaatc cattgcctgc gacaaatcgg tctttccgca taaattcaca
    10201 catatgccgt ctgaaaggcg gttgatttcc tcggcaattt catcatcttt ttgcgaaccg
    10261 aacagccaaa cctgccaacc cgccgccgaa taatgtttgc ccaactcggc aaaatgcttt
    10321 gtcggccaac gctttgccgg cccgaattcc gcacccggac aaaaagccag aacaggcttt
    10381 ccaatatcca agccaaaggt ttcgacagaa atttcccgcc gccgttcatc aatggaaaac
    10441 tcggggaatc ccgaatgccc gtcaaaatcc tcctggctcg gatgcgcgag agccgtatat
    10501 ctgtccacca tcaaaggcag acgttcctta tccagcctgc gtatatcgtt caacagaaaa
    10561 taacggcttt caccgacata acccgttctt tttccgatgc ccgttgccag cgcgatgact
    10621 gccgacttca aagaacccgg caacacaata acctgatcgt atccgcgccg ccccaaatcc
    10681 ctgccgaccc gccaacggcg tttcaactcc aacgcaccgt gtccgaacgg attttcaaga
    10741 atctcattca cttccggcat acgctcaaac accgccatcg accacttcgg tgcgaacaca
    10801 tcaatcgtgc aaccgggatg aagttccttc aaacggcgga acaagggctg ggtcatcacg
    10861 cagtcgccta tccaactggg agaaataatc aggattttga tggacataac aagaaaccga
    10921 aatcagacag gcagaatttt accgcgaaac cgttggaaaa cctatcttgc cgcattccga
    10981 acgccggacg tgcaaatatg aaaaagcccg aacattcaag ttcgggcttc aaaattctgg
    11041 ctccccgacc tgggctcgaa ccagggacct gcggattaac agtccgtcgc tctaccgact
    11101 gagctatcgg ggaatggggc gtattatagc gtccggaaaa aatgtgtcaa tccttaattt
    11161 tggaaaaatg ggcgacaaaa cgacaagcat atgaatcaga aagacattaa gaccgatgcc
    11221 ttaaaaggat tgccgttgta tgaatttcca cagccgtcat cacaccatat ttaagcccga
    11281 tgagccgttc tgccctcccc cgcttaaaac aatgccgtct gaacttcgcc gcgttccaaa
    11341 gccagtaaaa actgtttgcg gttcaacccg cccgcgtagc cggtcagttt gccgtcgctg
    11401 ccgatgacgc ggtggcaggg aatcaggata gatactttgt tctgcccgtt ggcggcggca
    11461 acggcgcgga cggctttggg gttgcccaaa cgctgcgcct gctccttgta gctgcgcgtt
    11521 tcgccgtaag gaatcgccaa gagcgcgtcc catgcctgct tttgaaactc ggtgccaatc
    11581 tgctccaaag gcgtggcaaa ggttttcaga cgacccttga agtataagtc caattcctgc
    11641 cgcaaaagtt gcgtccgctc atcctcccga aacacaaacc gtccgcgcaa ggctttttgg
    11701 acggcggcaa tttcctgttc caaatgcttc tgtccgacaa actccagcag acacaatccc
    11761 ttatttccga acaccgccag catctcgccc aaaggcgtgg caatggcggc acacaccagc
    11821 tcgttcaagc tgtcgggata acgcgcttcc aacaaacgga tggcgcggcg gatgcggaca
    11881 tattcttcag gcgcgcagcc gatattgtcc caaaaatccc gatcgaactg cccggcttcg
    11941 cactccgtca gattgggatg cggcataacg ccgcactcaa aaacccgggt ttcgagccaa
    12001 tagcggattt catcccattt tgacggcaga ttgtttaagg aaggcagggt aatcattcgt
    12061 ttgctccgta tctctatcat ggatttggcg gcaaaatccc caatttttgc cattcccgca
    12121 cgccgatgca ggaacgggct atgacgtaaa tcttgagggt tgggttgcgg caatgcctaa
    12181 atatgcgata tttccaaagc atcagagaaa ggaatgtttc aacacacagg acgacacata
    12241 aagcgccgcc ccatgaaaaa tttcagacgg ccttcaaagg ctcgtctgaa accacgattt
    12301 ttgcatttgc gcattctggc acatcatcca accgtttcgg cacattcctg ccgccgttga
    12361 cagcctataa tgaatccact tattcatcaa gcaaaggaat catctatgca aacccgcatt
    12421 ctctccgccg tactgctggc tttttcaacc gctgcctttg ccgggggcgc attcacgctg
    12481 caattcgaca acccgtccga agacggcggc ttcacgcaaa accagctttt gagcgcgcct
    12541 tacggatttg gctgttcggg cggcaatgct tcgcccgcgc tgtcgtggaa aaatccgccc
    12601 gccgggacaa aaagtttcgt cctgaccgtt tacgataaag acgcgccgac cggactgggc
    12661 tggatgcacc gggtggtcgc cgacattccc gccgatgtcc accgccgcaa cgcgacctcg
    12721 ctgcaattaa gccgctgcgc caacatcgcc gaccggactg ggctggatgc actgggtggt
    12781 cgccgacatt cccgccgatg tccgccgccg caacgcggcc tcgctgcaat taagccgctg
    12841 cgccaacatc gccgacgacc agtccgcagc catatcggcg gtaatcagtt tgcggatttg
    12901 ccgcatcagg ttgacgcctt cgtacacggc aaaaccgatg ccgtcatgct gcaaccacgc
    12961 caacacgccg caaagcgcga cctccgccgc attgtgcggc acttcttcat ccgtcagcac
    13021 cgccgccgca taatcaaacg ccgcgcccat ccgcccgggg tgcggcagct tcaccgcatc
    13081 gcacactgcc tgcgccgtcc cgtattgtgc ggcaaacctt tctatggctt cctgttcgaa
    13141 agcaatccat tgcgcctgat agaggccgtc tgaatcggga atattaataa cgtcaaacgt
    13201 ctgtccgcct gccaacgcaa ccgcctcacc cgccgcaatc ctcaattcgc gcctcgccca
    13261 ccgcagcttc ttgcttccgc gccgcacgat aagcacagct ggttcatata ccgccacgct
    13321 gcggtacaag gcggtatgat gttgcacgat gccgcccaaa gcacccaatc gttcgcgcgt
    13381 atgaaagtat agtggattaa atttaaatca ggacaaggcg acgaagccgc agacagtaca
    13441 aatcgtacgg caaggcaagg caacgccgta ctggtttaaa tttaatccac tatatctcaa
    13501 acccacgtta ggtctaagca aatggtcgga catccttatc cgacagccca tcttcttttc
    13561 agacggcatt gcaaatttaa gtttgacgtg cgttcaaaat aaggcagtta atgcgaagcc
    13621 aaattccgtc ggcgtgcctg caacttgact ccctcccctg tgggggaggg ttggggagag
    13681 ggtaaaacgg ggcagataca gacaatattt ccgttaccgc cccgatgccc tctccctaac
    13741 cctctcccac gggagaggga atggattgcc gtttaaataa aaaaatctac ataaaaatca
    13801 atgttttata gtggattaaa tttaaatcag gacaaggcga cgaagccgca gacagtacaa
    13861 atagtacggc aaggcgaggc aacgccgtac tggtttgaat ttaatccact atatctcaaa
    13921 cccacattag gtctaatcaa atggtcggac atccatatcc gacagcccat tttcttttca
    13981 gacggcattt ccagccaaca agcgcgccaa tatcccctca tacaccgccg acagcttcgg
    14041 aatatcgtcc agccgcacgt tttcgttgat ttggtggatg gtcgcattgg acgggcctaa
    14101 ttcgatgagt tctttcgcaa tggctttaat gaagcgtccg tccgaagtgc cgccggtggt
    14161 ggacaattcg gtctctacgc cgcaggtttc ggcaatggct gcgcgtgcca cgtcggtcag
    14221 tttgcccgcg tgggtcagaa agggctgccc cgaacacgac cattgcaaat cgtattgcac
    14281 gccgtgtttg tccaaaatgg tatggacgcg ttgtttcagc cctgcttcgg tggactcggt
    14341 ggaaaagcgg aaattgaatt tgacgttcag ctcgcccgga atgacattgg tcgcgcctgt
    14401 gccgccgttg atattggaaa tttgaaagct ggtcggcggg aagtattcgt tgccttcgtc
    14461 ccagacttcc tgcgtcaact ctaacaaggc aggggcaaaa gtatgcacgg gattgattgc
    14521 caaatgcgga taggcaatat ggccttgctt gcctttgacg gtcaggttgc ccgacagcga
    14581 gccgcgccga ccgtttttaa tcatatcgcc caatttgtcc acggcggtcg gttcgccgac
    14641 gatgcagtag tcaatcaact cgccgcgcgc tttcaacaca tcgacgactt tggtcgtgcc
    14701 gtccagcgcg tcgccctctt cgtcggaagt aatcaggagc gcgatgctgc cttgatgatc
    14761 ggggtgttcg gcaacaaagc gttcgcaggc ggtaacgaaa caggcgatgc cggttttcat
    14821 gtccgccgcg ccgcgcccgt ataatcttcc gtctcgctcg gtcggctcga acgggggcga
    14881 atcccatttt tcaacagggc cggtcggtac aacgtcggta tgccctgcaa aacagacgac
    14941 gggagctttc gtgccgcgtc gcaaccagat gtttttggtg tcgccgaaat ggagttcttc
    15001 agccgcaaaa ccgattttgt gcaggcgttc ggcaagcagt ttttggcaat tttggtcatc
    15061 cggcgtaacg gacggtcggg caatcaattc tttggcaagc tctagggatc gggtttcggt
    15121 catttttcgg cttttctgtt tgagatgccg tctgaacggc gtttcagacg gcatttgatg
    15181 ttgaatggaa cgggctaacg atagcgaagc gggttcttca ggtcaagcac catgacacgc
    15241 ttcgtaaagc ggcagcaaat cttccaccgt ttccgctatc catttcgcga catcctgcct
    15301 gcccaaatcg tcgcgttcga tgtgtttgcc gatgcagaaa aagtcttcgt cgttttgcaa
    15361 ctttcggtcg gactcgtttt gttgcgcgac ggtgcggtag tcgtcgtatt cgctttccgc
    15421 accgtgccac atatcgaaag aagcgtattt ttcggtatca aaattatcca accagcggtt
    15481 gtaatcgggc agcgcaatcg gcgacacgtc ggctttatag cagtgccaat ccaagctgac
    15541 gctcagacgg cggcggttga gcagtatcga caaaatcgct gcggaatttt tatattgttc
    15601 gtatttgaag taggcaaaga aatgggcgcg aacctgccag ccgttgcacc agcgttcgat
    15661 gtgcggcggc gcaaacggcg cacccaattc ggcggcaacc tgctgaatca gctgctgcca
    15721 tatctgccag ttttctttat agtcagcctt gatttgcgga atgctttcag gctggtattt
    15781 tttaagctgg gaaaattgga aaaacgggat attgaacaaa tcgcaacttt tcggggtcag
    15841 cataatatat ccttgagacg attgtttcag acggcattat ttgcgccggc gcgccgccat
    15901 aatttcgccg atttcggtca gtttttcttt tgggataaag gtgttgccca tatcaaacag
    15961 cggctcttca atcgccaaat gaacatcata tcccgccaca aaacgtttga acgcttcctc
    16021 atcggggaca taagcgttgt ctgcttcgag tttggcaaat tcggcggaaa cagccgccca
    16081 gttgtcgtgc agcccgatat gttggcgcaa aagctcgtcc acgctttctt gggcttgcgg
    16141 cgcatattgc agcagcagcg ggaagaagtt ttcttcttcg tcttcatggt gcagcggcgc
    16201 ggcaacgttg aaatactggg cgatttggcg gatggtttgc aaaacaatct gattgcagcc
    16261 gttttcggcg atatagtccg acagcatggc gacttgtccg caaaaacggc gcactttgcc
    16321 gtggcaggca tacagcattt caatcggttc ggcaaaggta acgcttttgg tttcaaacgg
    16381 attcatgttt tcgttctcaa cgggcacttt tcaagcagtc attttataat aaaacagcct
    16441 gcacaaagca ggctgtccgt cttttgagac tttaagcgga ttaatcgacc aaagtcactt
    16501 tgccgttcat caaagcaccg tgacccggga aggtgcaggc aaatttgtag tcgccgtcag
    16561 ccaatttggc aggatccaaa gtcagggaag actcttcgcc gccgccgatc agtttggtgt
    16621 gggcaacaac gcgcgcatcg tcaggtttga catagtcggt atcggcagca cctacaccgt
    16681 ctttaaatac gccgtccatg tcttcagctt tggcaatcac aaggttgtga cccatgctgg
    16741 ctttgggttg cgtaccggta tgtttcagag tgatggtgaa ctctttacat gctttgctga
    16801 cttggatgtc tttggtgttg aactgcatat tgtcgttgga ttcgacagtt gccgcacagt
    16861 tgccggcagc aggggcttcg gcagcatctg caggagcagc ttcggcggca ggcgcttcgg
    16921 aagcgggtgc ttcagcagca ggagttgcct cggcagcagg cgcggcaggt tcttgagagc
    16981 aggcagccaa accgataacg gcggcagaaa tcagagccag ataagctttc ataacaaatc
    17041 tccaatcgat aaaataatat tcggttttac agaaatcaaa gtgcaaccgc cattaacaaa
    17101 accttgaaaa agattccgcc gcgttgcaca aacagatgtt tcggagcggt attttgctac
    17161 aaatttcatt tgaaatcaaa gcctgtctgc aagtttacaa tcgtttactt taaaaggggc
    17221 aattttaccc cgaacctatt tctttagtat tagggaagcc gtcccccgct gcgcaaatat
    17281 taacggatat ttacaacatc cctgccggcc gccttatgcc ccgtgcttcc tgaccagctc
    17341 cgccagcact gccgccaatt cgggatgccg tttttccaac tttgccgccg ccgaaccgaa
    17401 actctccagc gcagccttac tcaaatgcag ggtattggtt ttcggcggtt tttccggttt
    17461 cgggaccagc ctgaccgaaa cagagcgtat cgaaacatca agccctgcca actgcggcaa
    17521 taccgacggt gcaatcattt tcaaacgcga tgccgccata ttgtttgccg ccaaaaggac
    17581 aagcctgccg tcttcgatac atgccgtctg aaaatgcggg tgcaggttgg caggcagcag
    17641 ttttttcacg gcggcatcca accgccgcca ctgtcccgcc tgtttcaaaa gtccggaaag
    17701 cagcgcgtcc cgcctgccca actgttccaa attcataaaa catacaccca aaaagattga
    17761 aataccgcaa acacgccttt atttcagacg gcattagcac tttgcacaaa cgcttgtgtt
    17821 aaaatcgcgt tttcgcccac tattatatca ggcgcaggaa ttattcatgc tgacaaacat
    17881 tgccaagaaa atcttcggca gccgcaacga ccgcttgctg aaacaatacc gtaaatccgt
    17941 tgccagaatc aacgcgctcg aagaacagat gcaagcccta agcgatgctg atctgcaagc
    18001 caaaactgcc gaattcaaac aacgcctcgc cgacggtcag actttggacg gcattttgcc
    18061 cgaagccttc gccgtctgcc gcgaagcgtc ccgccgcacc ctcggtatgc gccacttcga
    18121 cgtgcagctt atcggcggta tggtgctgca cgacggcaaa atcgccgaaa tgcgtaccgg
    18181 cgaaggcaaa accctggtcg ccaccctcgc cgtctatctc aacgcgctgg ccggcaaagg
    18241 cgtacacgtc gttaccgtca acgactacct cgcctcacgc gatgcgggca ttatggagcc
    18301 gctctacaat ttcctcggcc tgaccgtcgg cgtgattatt tcagatatgc agccgttcga
    18361 ccgtcaaaac gcctatgccg ccgatatcac ctacggcacc aataatgaat tcggcttcga
    18421 ctacctgcgc gacaatatgg ttaccgacca atacgacaaa gtgcagcgcg aattgaattt
    18481 tgccgttgtc gatgaagtgg attccatctt gattgacgaa gcgcgcactc cgctgattat
    18541 ctccggtcag gcggatgaca acatccagtt gtaccaaatc atgaacaccg ttccgcccca
    18601 cctcgtccgt caagagacag aagaaggcga aggcgactat tggatcgacg aaaaggcaca
    18661 tcaggtcatc ctgagcgaag caggtcacga acacgccgag caaatcctga cccaaatggg
    18721 attgctggca gaaaacgact ccctctattc cgccgccaat atcgccctga tgcaccacct
    18781 tatggcggca ttgcgcgcgc attccctctt ccacaaagac caacattacg tcatccaaga
    18841 cggcgaaatc gtcatcgtgg acgaattcac cggccggctg atgtccggcc gccgctggtc
    18901 ggagggtctg catcaagccg tcgaagccaa agaaggcgtg gaaatcaaac gcgaaaacca
    18961 aaccctcgcc tccatcacct tccaaaacta tttccgcctg tacaccaagc tctccggtat
    19021 gaccggtacg gcagataccg aggctttcga gttccaaagc atttataacc tcgaaaccgt
    19081 cattatcccg accaaccgcc ccgtacagcg caaagacttc aacgaccaga ttttccgttc
    19141 cgccgaagaa aaattcgaag ccgtcgtcaa agacatcgaa gaatgccaca aacgtgggca
    19201 gcccgtcctc gtcggcacca ccagcatcga aaactccgaa ctggtctccc accttctgca
    19261 aaaagccgga ctgccgcaca acgtcctcaa cgccaaagaa cacgaacgcg aagccctgat
    19321 tgtcgcccaa gccggcaaag tcggcgcgat taccgttgcc accaatatgg cgggacgcgg
    19381 tacggacatc gttttaggcg gcaacctgaa gcaccaaacc gatgccatcc gtgccgacga
    19441 aaccttgagc gacgaagaga aacaggcaca aatcgccgca ctcgaaaacg gctggcaggc
    19501 agaacacgat aaagtaatgg aagcaggcgg cctgcacatc atcggtacgg aacgccacga
    19561 aagccgccgt atcgacaacc aattgcgcgg acgttccggc cgtcagggcg accccggatc
    19621 cagccgtttc tacctttcgt ttgaagaccc gctgctgcgc ttattcgcac tcgaccgcgc
    19681 cgccgccatc ctcaaccgtc tcgcccccga acgcggcgtt gccatcgaac acaacctgct
    19741 gacgcgccaa atcgaagggg cgcaacgcaa agtcgaaggc agaaacttcg atatgcgcaa
    19801 acaggttttg gaatacgacg acgttgccaa cgaacagcgc aaagtcattt acagccagcg
    19861 caacgaaatt ctgaccagca aagacatcag cgacctgatg caggaaatcc gttctgatgt
    19921 cgtcagcgac ctcgtggata cctatatgcc tcccgacagc atggaagaac aatgggacat
    19981 cccgactttg gagaaccgtc tggctgccga attcagactg cacgaagaca tccaatcctg
    20041 gctgaaggcg gacaatgcga ttgacggtca agacatcaaa gaacgcctga tcgaacgcat
    20101 cgaaaacgaa tatgccgcca aaaccgaact ggtcggtaag caggcaatgg ccgatttcga
    20161 gcgcaacgtg atgttgcagg tcatcgacaa ccaatggcgc gaacacctcg ccgctatgga
    20221 ctacctgcga caaggcatac acctgcgcag ctatgcccaa aaaaatccga agcaggaata
    20281 taaacgtgaa gcctttacca tgttccaaga cctgtggaac ggcatcaaat tccatattgc
    20341 ctccctgctt acctcggttc aaatcgaaca aaaccctgtc gcggtggttg aagagcaacc
    20401 catcggcaac atccagtcca tccattccga atcgcccgat atggaagaac ttttgggtca
    20461 gtcgcaaacc gatttggtta ccgaggcctt taatcccgat ggaacggatt tcagccccga
    20521 agccttggaa gcgcggggac aaatcgtcca ccgcaacgac ccctgcccct gcggcagcgg
    20581 tttgaaatac aaacaatgcc acggcaaact ggcttaagcg tttgaacgca aatgccgtct
    20641 gaacatccga tttccggttt cagacggcat tttgcctgaa ccgccacatc cgactgccat
    20701 tccgaaaaat cccgatttcg taccgtccgt accaaaaaca gacatcccgt ccgccccaca
    20761 tcatgattcc atccgacttc attgacgagc ttttagccaa aaccgatatt gtcgatatta
    20821 tcgacgagca ggttccgctg aaaaaaggcg gggcgaacta tatggcgtgt tgcccgttcc
    20881 acaaggaaaa aacgccgtcg ttttcggtca gtccgaccaa acagttttac cactgtttca
    20941 gttgcggggc gcacggttcg gcgattggtt ttgtgatgga acatcagggg ctgtcgtttc
    21001 cggaggcggt gcagttcctt gccgaccgcg tgggtatgat tgtgcctaaa gtgcgcgggc
    21061 aaaacgataa tcccgaagtc cgtgccgagc gcaagaaaaa acagcagacg ctggaggaaa
    21121 cgacggctgc ggcagctgat ttttatgcgc aacagctaaa attcaatccg gcggcaaaag
    21181 cttatttgga caagcgcggc ttgagtgcag aagttatcgc gcattatggt ttgggctacg
    21241 cgcccgacgg ctggcagcct ttggcgcaag tgttccaacc gtatccgaat accgcgttgg
    21301 tggatacggg gatggtgatt gacaatgagg ggcggtatta cgaccgcttc cgccatcgga
    21361 ttatgttccc tatccgcaat ccgcgcgggc aggtcatcgg tttcggcggc agggtgctgg
    21421 acgactccaa acccaaatat ctaaactctc ccgatacacc tttgtttgac aaagggaaaa
    21481 acctttacgg cttgtatgag gggcgtgccg ctgtcaagga agcggagcgg attctggtgg
    21541 tcgaaggcta tatggacgtg gtcgcgctgg cacagttcgg cgtgggctac ggcgtggcgg
    21601 ccttgggcac ggcaacaaca gcggaacacg tcaaaatcct gatgcgtcag gcggacagta
    21661 tttatttctg tttcgacggc gacagcgcgg ggcgcaaagc ggcttggcgc gcgctggaaa
    21721 acgcgttgcc gcagttgaaa gacgacaaat cgctgcattt tttgttcctg cccgaggaac
    21781 acgaccccga cagttacatc cgtgcctacg gcaaagcgca atttgaagac gcgcttctga
    21841 atcaaagcaa gcctttgtcg gagtatttct gggaacacct ttcagacggc attcatctca
    21901 atacgcagga aggcaaggcg gaattggtga aaaccagttc gccgcttttg gcgcagatta
    21961 ccgcgccggc attggcttat ttgttaaaac aacggcttag cgaactggtc ggcatcgacc
    22021 ccgacaacct cgcgcaactg ctaggactgg aagcgccgaa gcggcacgtc aaacaaaaaa
    22081 actacaaact gcctccgatt tccgtcaaac agcccgtcat gctgacgctg gtacagcggc
    22141 aaatccgcag cctcttgata aatccggatt gggctgcata tatagacctg cccgattatc
    22201 tggcgttgga cggtgatttc gcctgccttg ccaatcttgc cgaatcgatt aaaaaccatg
    22261 ccgccgtacc cgaaaccgct caggttttag agtatatgcg cggctcgcct tacgaagaaa
    22321 cgataacccg aatcttccat tcaacgcacc aatcggaaga aatgaacagc agcagtgaag
    22381 aagattgcga gaatttccaa atcggcatga aaaaactgct caatgagtta aaatacagcc
    22441 aaatcgaagc attgaaacaa aaaagcctgc aatccggctt aaatgaaagc gagaaaaaac
    22501 ttttgctgtc gttgctgacc gcaaaacaaa attgaccggc ggattccgcc acccgtaaac
    22561 ccgttatgcc gtctgaaaag cacttacccc ggctgcaaca acgacacctg cagaacaccc
    22621 atcccaaaaa gccttcagac ggcatcagag tacccgctct gccacgcctt caggtgcgtt
    22681 caaacgcaaa ccgtcggcac cttaccaaca gaaagcagac aatgtccaga aaccaaaatc
    22741 acgaagaata tcaagacgac acccgtccgt taagcattga agagcaacgc gcgcgcctgc
    22801 gtcagctcat catcatgggt aaagaacgcg gctacatcac ctactccgaa atcaacgacg
    22861 ccctgccaga cgatatgtct gatgccgacc aaatagacaa tatcgtcagc atgatttccg
    22921 gtttgggcat ccaagttacc gaacacgccc ccgatgcgga agacatattg ttaagcgaca
    22981 atgccgccgt taccgacgat gatgccgtcg aagaagccga ggccgccctt tccagtgcag
    23041 attccgagtt cggcagaacc accgaccccg tccgtatgta tatgcgcgaa atggggcagg
    23101 tcgacctgct gacccgcgaa gacgaaatca tcatcgcaaa aaaaattgaa aacgccctga
    23161 aaaatatggt tcaggccatc tccgcctgcc cgggatccat tgcggaaatc ttagaactca
    23221 tcgaaaaaat ccgcaaagac gaaatccgcg tcgacgaagt cgtagaagcc attatcgacc
    23281 cgaatgaagt attgctcaac gaattgggct tggggcactt ggaaaccaca gcgcccgaga
    23341 aaccttccaa cgacaattcg gacgaaaacg aagacgacga agaatcggaa gaagatgcgg
    23401 atgaaatctc ggcagccaat ctcgccgaat tgaaacaaaa agtcatcggc cactttgccc
    23461 aaatcgaaaa agactacaaa aaaatgattg gccgtttgga aaaacaccac agccggcaca
    23521 aagactatct cgcctaccgc gacgcgattg ccaacaaact gctggaagtc cgtttcgcca
    23581 cccggcaaat cgacagcctc agcagcagcc tgcgcggaaa agtagaaaac atccgcaaac
    23641 tcgaacgcga aatccgcgac atctgcctcg accgcgtcca tatggagcgc gactacttca
    23701 tccaaaactt cctgcccgaa atcaccaatc tggaatggat tgaagaagaa atcgccaaag
    23761 gcagggtttg gagcgacgcg ctcgaccgct tccgccacgc catcctcgaa aaacaaaccg
    23821 agttggcaga tatggaaaaa gaaacccgca tttccatcga agagttgaaa gaaatcaaca
    23881 aaaatatggt gtcgagcgaa aaagaaaccg cagccgccaa acaggaaatg attcaggcaa
    23941 acttgcgcct cgtcatttcc attgccaaaa aatacaccaa ccgtggcttg cagttccttg
    24001 atttgattca ggaaggtaac atcggcctga tgaaagcggt cgacaagttc gaataccgcc
    24061 ggggctacaa attctccacc tacgcaacct ggtggatccg ccaggcaatc acccgttcga
    24121 ttgccgatca ggcgcgtacc atccgcattc cggtacatat gattgaaacc atcaacaaga
    24181 tgaaccgcat ctcgcgccaa caccttcaag aaaccggcga agaacccgat tccgccaaac
    24241 ttgccgaact gatgcagatg cccgaagaca aaatccgcaa aatcatgaaa atcgccaaag
    24301 agccgatttc gatggaaacc cccatcggcg acgacgacga ttcgcacttg ggcgacttca
    24361 tcgaagatgc caacaatgtt gcgccggccg atgcggcaat gtacaccagc ctgcacgaag
    24421 taaccaaaga aatcctcgaa agcctgacac cgcgtgaggc aaaagtcctg cgtatgcgtt
    24481 tcggcatcga tatgaacacc gaccacacgc tggaagaagt cggcagacag tttgacgtaa
    24541 cgcgcgaacg catccgacaa atcgaggcaa aagcactccg caagctgcgg catccgacaa
    24601 gaagcgaccg tttgagaagt ttcttggaca gcgaagacag caagctgtaa accaaaaaac
    24661 cgcaggtttc aaatacctgc ggttttttct tacacaataa acaacgcttc cacatatccc
    24721 acactcctat cccgagacct ttgcaaaatc ccccaaaatc ccctaaattc ccaccaagac
    24781 atttaggaga ttttccatga gcaccttctt tcaacaaacc gcgcaagcca tgattgctaa
    24841 acacatcgac cgtttccctc tattgaagtt ggatcaagtg attgattggc agccgatcga
    24901 acaatacctg aatcgtcaaa aaacccgtta ccttcgagac caccgcggcc gtcctgccta
    24961 tcccctgctg tccatgttca aagccatcct gcccggacaa tggcacagcc tctccgatcc
    25021 cgaactcgaa cacagcctca ttacccgcat cgatttcaac ctgttttgcc gttttgacga
    25081 actaagcatc cccgattaca gcaccttatg ccgttaccgc aaccggctgg cgcaagacga
    25141 caccctgtcc gaactgttgg aactgattaa ccgccaactg accgaaaaag gcttaaaaat
    25201 agagaaagca tccgccgccg tcgttgacgc caccattatt caaaccgccg gcagcaaaca
    25261 gcgtcaggcc atagaagtcg atgaagaagg acaaatcaac ggccaaacca caccgagtaa
    25321 ggacagcgat gcccgttgga taaagaaaaa cggcctctac aaactcggtt acaaacaaca
    25381 tacccgcacc gatgcggaag gctatatcga gaaactgcac atcaccccag ccaataccca
    25441 tgagtgcaac cacctgttgc ctttgctgga aggcattacc gaaggcacga ccatctatgc
    25501 cgacaaaggc tatgacagtg cggaaaaccg gcaacatctg gaagaacatc agttgctg
//
LOCUS       DAXIDM010000017        25486 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000017 DAXIDM010000000
VERSION     DAXIDM010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 25486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25486
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.017"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..808
                     /locus_tag="ACFOAE_000588"
     CDS             <1..808
                     /locus_tag="ACFOAE_000588"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC6884130.1"
                     /translation="RYRTPNIKYIYQDNQGTAEARNTGIKNSNGKYIVFIDSDDFINC
                     QVLLDFLSKDDIDMPDVVFLNAVKYDKGSVSHFGEDYQPEKILNQSKVEVLKGLCRFR
                     KFPGSACNKIIKRELIIKEKLFFEKEVYAEDIEWSMRLFNAATTFSYLDGCYYYYRQG
                     RKDSKTGTVSEKSIKSLLYILEKNAEMEFNRDISSYLYSFLSYEYLVLLFIMTSKNIE
                     CDADIKRRAYHLRFMLLKSNKLIYKLIFPIITLFGVDITGRILKVIRGNV"
     gene            849..1379
                     /locus_tag="ACFOAE_000589"
     CDS             849..1379
                     /locus_tag="ACFOAE_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFC6884131.1"
                     /translation="MNAIRTFQNRTPEIHESCMIDEACVVIGEVSLAEDVSVWPCAVL
                     RGDVNSITVGARSNIQDGSVLHVSHKTAAKPEGSPLVIGEDVTVGHKVMLHGCRIGNR
                     VLVGMGSTVLDDAVIEDEVMIGAGSLVPPRKRLAGGYLYIGSPVRQVRVLTDEEKAFL
                     KYSAAHYVKLSKQYGM"
     gene            complement(1413..1529)
                     /locus_tag="ACFOAE_000590"
     CDS             complement(1413..1529)
                     /locus_tag="ACFOAE_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor domain protein"
                     /protein_id="HFC6884132.1"
                     /translation="MPSKPEKRASDGIFACNSNADGQNQGASDTVIGCIPSA"
     gene            complement(1548..3143)
                     /locus_tag="ACFOAE_000591"
     CDS             complement(1548..3143)
                     /locus_tag="ACFOAE_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007342770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFC6884133.1"
                     /translation="MSQEILDQVRRRRTFAIISHPDAGKTTLTEKLLLFSGAIQSAGT
                     VKGKKTGKFATSDWMDIEKQRGISVASSVMQFDYKDHTVNLLDTPGHQDFSEDTYRVL
                     TAVDSALMVIDAAKGVEAQTIKLLNVCRLRDTPIVTFMNKYDREVRDSLELLDEVENI
                     LQIRCAPVTWPIGMGKNFKGVYHILNDEIYLFEAGGERLPHEFDIIKGIENPELEQRF
                     PLEIQQLRDEIELVQAASNEFNLDEFLAGELTPVFFGSAINNFGIQEILNSLIDWAPA
                     PKPRDATVRMVEPDEAKFSGFIFKIQANMDPKHRDRIAFLRVCSGRFERGMKMKHLRI
                     NREIAASSVVTFMSHDRELVEEAYAGDIIGIPNHGNIQIGDSFSEGEQLTFTGIPFFA
                     PELFRSVRIKNPLKIKQLQKGLQQLGEEGAVQVFKPMSGADLILGAVGVLQFEVVTSR
                     LANEYGVEAVFDSASIWSARWVSCDDKKKLAEFEKANAGNLAIDAGGNLAYLAPNRVN
                     LGLTQERWPDIVFHETREHSVKL"
     gene            complement(3250..3645)
                     /gene="hisI"
                     /locus_tag="ACFOAE_000592"
     CDS             complement(3250..3645)
                     /gene="hisI"
                     /locus_tag="ACFOAE_000592"
                     /EC_number="3.5.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="HFC6884134.1"
                     /translation="MDKNLLEAVKFDEKGLVCAIAQDAETKRILMVAWMNAEALQKTV
                     ETGFAHYYSRSRQKQWMKGEESGHTQKVRELRLDCDGDAIVMLIAQNGGIACHTGRES
                     CFYKVWRGSAWETADAVLKDEKEIYGSTH"
     gene            complement(3676..4443)
                     /gene="hisF"
                     /locus_tag="ACFOAE_000593"
     CDS             complement(3676..4443)
                     /gene="hisF"
                     /locus_tag="ACFOAE_000593"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HFC6884135.1"
                     /translation="MALAKRIIPCLDVKDGRVVKGVNFIGLRDAGDPVEAAKRYNGEG
                     ADELTFLDITASSDNRDTILHIIEEVAGQVFIPLTVGGGVRTVADIRRLLNAGADKVS
                     INTAAVTRPDLIDEAAGFFGSQAIVAAVDAKAVNPGNTRWEIFTHGGRNPTGLDAVEW
                     AIEMQKRGAGEILLTGMDRDGTKQGFNLPLTRAVAEAVDIPVIASGGVGNVRHLIEGI
                     TEGKADAVLAAGVFHFGEIAIREAKRAMREAGIEVRL"
     gene            complement(4456..5193)
                     /gene="hisA"
                     /locus_tag="ACFOAE_000594"
     CDS             complement(4456..5193)
                     /gene="hisA"
                     /locus_tag="ACFOAE_000594"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003949 -
                     1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HFC6884136.1"
                     /translation="MLLIPAIDLKEGRCVRLRQGLMEEATVFSDSPAETALHWFKQGA
                     RRLHLVDLNGAFAGVPQNLPAIKDILAAVAKDIPVQLGGGIRDLKTIGQYLDLGLNDV
                     IIGTAAVKNPDFVREACKAFPGRIIVGLDAKDGMAAIDGWATVTGHHVIDLAKRFEDD
                     GVNSIIYTDIGRDGMMSGVNIDATVKLAQTVRIPVIASGGLTGLDDIRALCAAEKHGV
                     AGAITGRAIYEGSIDFAQAQQLADSLD"
     gene            complement(5226..5864)
                     /gene="hisH"
                     /locus_tag="ACFOAE_000595"
     CDS             complement(5226..5864)
                     /gene="hisH"
                     /locus_tag="ACFOAE_000595"
                     /EC_number="4.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HFC6884137.1"
                     /translation="MQIAIIDYGMGNLHSVLKSVRTAGQLAGKNTEIFLSGDPERVSR
                     ADKVIFPGQGAMPDCMAALTRGGLDEAVKDALKNKPFFGICVGAQLLFDHSEEGNTDG
                     LGWFGGKVRRFERDLRDPQGCRLKVPHMGWNTVRQTQNHPLFKDIPQDTRFYFVHSYY
                     FAPENPETILGESDYPSPFACIVGKDNVFATQFHTEKSHDAGLTMLKNFLNW"
     gene            complement(5995..7497)
                     /gene="pta"
                     /locus_tag="ACFOAE_000596"
     CDS             complement(5995..7497)
                     /gene="pta"
                     /locus_tag="ACFOAE_000596"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFC6884138.1"
                     /translation="MAKVLIVPVSAGLDASAAAQAFAKALDAQIFQAVDATAETLLAQ
                     GKSDDWFDALVGKVAALDAANLVIEGIAPDADKIYLAGKNVELALSLDAAAVFAVRSD
                     NADADELANRLNLAKQFFAAAPGVLEGFVVDGAAASVAEAAAEKTGLTFFGSSDALKD
                     VSVLAGREAKRLSPAQFRYNLIDFARQADKRIVLPEGAEPRTVQAAAICHEKGIARCV
                     LLAKREEVEAVAKERGISLPDSLEIIDPASLVEQYVEPMCELRKSKGLTPEDARKQLQ
                     DTVVLGTMMMAQNDVDGLVSGAVHTTANTIRPALQLIKTAPGASLVSSVFFMLLPNQV
                     LVFGDCAVNPNPTAQQLADIAIQSADSAKAFGIDPKVAMISYSTVNSGSGPDVDTVIE
                     ATKLAREKRPDLAIDGPLQYDAATVQGVGKSKAPGSPVAGQATVLVFPDLNTGNCTYK
                     AVQRNANVLSVGPLLQGLRKPVNDLSRGALVEDIVFTIALTAVQAKQMEG"
     gene            complement(7682..8740)
                     /gene="fbpC"
                     /locus_tag="ACFOAE_000597"
     CDS             complement(7682..8740)
                     /gene="fbpC"
                     /locus_tag="ACFOAE_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein FbpC"
                     /protein_id="HFC6884139.1"
                     /translation="MTAALHIGHLSKSFQNTPVLNDISLSLDPGEILFIVGASGCGKT
                     TLLRCLAGFEQPDFGEISLSGRTIFSKNTNLPVRERRLGYVVQEGVLFPHLTVYRNTA
                     YGLGNGKGKTAQERQRIEAMLELTGISELAGRYPHELSGGQQQRVALARALAPDPELI
                     LLDEPFSALDEQLRRQIREDMIAALRANGKSAVFVSHDREEALQYADRIAVMKQGRIL
                     QTASPHELYRQPADLDAALFIGEGIVFPAALNADGTADCGLGRLPVQSGAPAGTRGTL
                     LIRPEQFSLHPHSAPTASIHAVVLKTTPKARHTEISLRVGQTVLTLNLPSAPTLSDGI
                     SAVLHLDGPALFFPGNTL"
     gene            complement(8761..10278)
                     /gene="fbpB"
                     /locus_tag="ACFOAE_000598"
     CDS             complement(8761..10278)
                     /gene="fbpB"
                     /locus_tag="ACFOAE_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease FbpB"
                     /protein_id="HFC6884140.1"
                     /translation="MSPKKIPIWLTGLILLIALPLTLPFLYVAMRSWQVGINRAVELL
                     FRPRMWDLLSNTLTMMAGVTLISIVLGIACALLFQRYRFFGKTFFQTAITLPLCIPAF
                     VSCFTWISLTFRVEGFWGTVMIMSLSSFPLAYLPVEAALKRISLSYEEVSLSLGKSRL
                     QTFFSAILPQLKPAIGSSVLLIALHMLVEFGAVSILNYPTFTTAIFQEYEMSYNNNTA
                     ALLSAVLMAVCGIVVFGESIFRGKAKIYHSGKGVARPYPVKTLKLPGQIGAIVFLSSL
                     LTLGIIIPFGVLIHWMMVGTSGTFALVSVFDAFIRSLSVSALGAILTILCALPLVWAS
                     VRYRNFLTVWIDRLPFLLHAVPGLVIALSLVYFSINYTPAVYQTFIVVILAYFMLYLP
                     MAQTTLRTSLEQLPKGMEQVGATLGRGHFFIFRTLVLPSILPGITAAFALVFLKLMKE
                     LTATLLLTTDDVHTLSTAVWEYTSDAQYAAATPYALMLVLFSGIPVFLLKKYAFK"
     gene            complement(10346..11341)
                     /gene="fbpA"
                     /locus_tag="ACFOAE_000599"
     CDS             complement(10346..11341)
                     /gene="fbpA"
                     /locus_tag="ACFOAE_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     FbpA"
                     /protein_id="HFC6884141.1"
                     /translation="MKTSIRYALLAAALTAATPALADITVYNGQHKEAAQAVADAFTR
                     ATGIKVKLNSAKGDQLAGQIKEEGSRSPADVFYSEQIPALATLSAANLLEPLPASTIN
                     ETRGKGVPVAAKKDWVALSGRSRVVVYDTRKLSEKDLEKSVLNYATPKWKNRIGYAPT
                     SGAFLEQVVAIVKLKGEAAALKWLKGLKEYGKPYAKNSVALQAVENGEIDAALINNYY
                     WHAFAREKGVQNVHTRLNFVRHRDPGALITYSGAAVLKSSQNKDEAKKFVAFLAGKEG
                     QRALTAVRAEYPLNPHVVSTFNLEPIAKLEAPQVSATTVSEKEHATRLLEQAGMK"
     gene            complement(11592..12057)
                     /locus_tag="ACFOAE_000600"
                     /pseudo
     CDS             complement(11592..12057)
                     /locus_tag="ACFOAE_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4375 domain-containing protein"
     gene            complement(12114..13490)
                     /gene="argH"
                     /locus_tag="ACFOAE_000601"
     CDS             complement(12114..13490)
                     /gene="argH"
                     /locus_tag="ACFOAE_000601"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HFC6884142.1"
                     /translation="MHDKTWSGRFNEPVSELVKQYTASIGFDRRLAEWDIQGSLAHAQ
                     MLKETGVLDEGDLADIRQGMAEILEEIRSGKIEWSSDLEDVHMNIERRLTDKIGDAGK
                     RLHTGRSRNDQVATDIRLWLRDQITVIQNLIQNLQTALLDLAEQNAETVMPGFTHLQV
                     AQPVSFGHHMLAYVEMLGRDNERMADCRRRVNRMPLGAAALAGTTYPIRREITAELLG
                     FEQICQNSLDAVSDRDFAVEFTAAASLIMVHLSRLSEELILWMSPRFGFIDIADRFCT
                     GSSIMPQKKNPDVPELVRGKSGRVIGHLIGLITLMKSQPLAYNKDNQEDKEPLFDTAD
                     TLIDTLRIYADMMRGVTVKPDNMRAAVMQGFATATDLADYLVKKGMPFRDAHEVVAQA
                     VRHADEAGVDLSELPLEVLQGFSKLISDDVYGVLTPEGSLNARNHLGGTAPEQVRLQV
                     KRWREVLA"
     gene            complement(13509..14378)
                     /gene="galU"
                     /locus_tag="ACFOAE_000602"
     CDS             complement(13509..14378)
                     /gene="galU"
                     /locus_tag="ACFOAE_000602"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFC6884143.1"
                     /translation="MKPIKKAVFPVAGMGTRFLPATKASPKEMLPIVDKPLIQYAVEE
                     AVEAGCTEMVFVTGRNKRSIEDHFDKAYELETELEMRHKDKLLEHVRNILPPNITCLY
                     IRQAEALGLGHAVLCARAAIGDEPFAVILADDLIDAPKGALKQMVEVYERSGNSILGV
                     ETVEPSQTGSYGIVETEQLKQFQRITGIVEKPKPEDAPSNLAVVGRYILTPRIFDLLT
                     NLPRGAGNEIQLTDGIAKLLDHEFVLAHPFEGTRYDCGSKLGYLEATVAYGLKHPETG
                     EPFRRLLEKYRTE"
     gene            complement(14406..15005)
                     /gene="rdgB"
                     /locus_tag="ACFOAE_000603"
     CDS             complement(14406..15005)
                     /gene="rdgB"
                     /locus_tag="ACFOAE_000603"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035870 - dITP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0036222 - XTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RdgB/HAM1 family non-canonical purine NTP
                     pyrophosphatase"
                     /protein_id="HFC6884144.1"
                     /translation="MSEKPEKIVLASGNAGKLKEFGNLFEPYGITVLPQSEFSIPECP
                     EPYSTFVENALAKARHAAGHSGLPALADDSGICAAALNGAPGIHSARYAGDNPKSDTA
                     NNLKLAAELVGKADKSCCYVCVLVFVRHKDDPRPIIAEGVWHGQWNGVPAGENGFGYD
                     PYFYLPGHGKTAAELDSEVKNRESHRAQALADLIRKLAL"
     gene            complement(14998..15231)
                     /locus_tag="ACFOAE_000604"
     CDS             complement(14998..15231)
                     /locus_tag="ACFOAE_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NGO_0222 family membrane protein"
                     /protein_id="HFC6884145.1"
                     /translation="MNRRKIYLLSVALFTLAFMLLVLLGAYLLTVGSKAFAVASFLFA
                     FGALFGQIGSLALYLRHKSLRAAQSAAKENRYV"
     gene            complement(15339..15872)
                     /locus_tag="ACFOAE_000605"
     CDS             complement(15339..15872)
                     /locus_tag="ACFOAE_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HFC6884146.1"
                     /translation="MADFNQILTPGDVDGGIINVVNEIPAGSNHKIEWNRKLAAFQLD
                     RVEPAIFAKPTNYGFIPQTLDEDGDELDVLLVTEQPLATGVFLEARVIGVMKFVDDGE
                     VDDKIVCVPADDRNNGNAYKTLSDLPQQLIKQIEFHFNHYKDLKKAGTTKVESWGDAE
                     EAKKVIKESIERWNKQA"
     gene            complement(15973..16431)
                     /gene="nudB"
                     /locus_tag="ACFOAE_000606"
     CDS             complement(15973..16431)
                     /gene="nudB"
                     /locus_tag="ACFOAE_000606"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008828 - dATP diphosphatase activity
                     [Evidence IEA];
                     GO_function: GO:0019177 - dihydroneopterin triphosphate
                     pyrophosphohydrolase activity [Evidence IEA];
                     GO_process: GO:0046656 - folic acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HFC6884147.1"
                     /translation="MPMAKPLKYPVSALVVLYSGDGGILLIERTHPEGFWQSVTGSLE
                     PGETVAQTARREVWEETGILLADGQLQDWHDSTVYEIYHHWRHRYPKGVFENREHLFS
                     AEIPRDTPIALQPEEHVSYGWFDMEEAAEKVFSPSNRRAILELGRFLGKR"
     gene            16642..16718
                     /locus_tag="ACFOAE_000607"
     tRNA            16642..16718
                     /locus_tag="ACFOAE_000607"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16676..16678,aa:Pro,seq:ggg)
     gene            16876..18381
                     /gene="mafB"
                     /locus_tag="ACFOAE_000608"
                     /pseudo
     CDS             16876..18381
                     /gene="mafB"
                     /locus_tag="ACFOAE_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244044.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 2"
     gene            18747..19163
                     /locus_tag="ACFOAE_000609"
     CDS             18747..19163
                     /locus_tag="ACFOAE_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884148.1"
                     /translation="MDIDLSMNNKKFSRYEILECLLYGGWSFLDDGNFVYLPLGDEDY
                     DWNSASMSEKEILDFLRIKSNLDEVIGFSITWADTNIGGQVLFFPNFEFSFSITINIK
                     NFDKDIVDVNWYLIKLLPIFDKNGILYNSIRYQEYR"
     gene            19395..19541
                     /locus_tag="ACFOAE_000610"
     CDS             19395..19541
                     /locus_tag="ACFOAE_000610"
                     /inference="COORDINATES: protein motif:HMM:NF012755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884149.1"
                     /translation="MWYEANIGLINTMSRSNQTGTRLLYSNDGLLYITTDHYISAIQI
                     GTWK"
     gene            19553..19840
                     /locus_tag="ACFOAE_000611"
     CDS             19553..19840
                     /locus_tag="ACFOAE_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003708044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HFC6884150.1"
                     /translation="MQLEIIGSKIYTEQDFHNQISKIFSIQDYYGNNLDALWDLLSTN
                     VERPITLVWKDAMFSKNQLENIFIEIVNVLERVKKQDEDYGFEEKFNYILE"
     gene            20354..21592
                     /locus_tag="ACFOAE_000612"
     CDS             20354..21592
                     /locus_tag="ACFOAE_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EndoU domain-containing protein"
                     /protein_id="HFC6884151.1"
                     /translation="MIASLTGAAVGGTPVDAQTGGAVGQNAVENNLYLTSEALKKDKQ
                     TARKIYSVIKEQVKHECSSTGRITECRQNIGRIIEFTQDKRFDSRFKDLKKESLYYLN
                     KHPDLVASYLKAEYEKLDREDKSILHRYISPGAEIVSGSLGVVLSGVAGGGSCAETFG
                     LGCAAALVGVTSSYDHVITGTKNFGKKASEQRPTIAVQALKQLGLSEQAAEYVQFSID
                     LFSVGKSGGGIPKAKPVFDAKPRWEVDRKLNKLTTREQVEKNVQETRRRSQSSQFKAH
                     AQREWENKTGLDFNHFIGGDINKKGTVTGGHSLTRGDVRVIQQTSAPDKHGVYQATVE
                     IKKPDGSWEVKTKKGGKVMTKHTMFPKDWDEARIRAEVTSAWESRIMLKDNKWQGTSK
                     SGIKIEGFTEPNRTAYPIYE"
     gene            21623..22042
                     /locus_tag="ACFOAE_000613"
     CDS             21623..22042
                     /locus_tag="ACFOAE_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884152.1"
                     /translation="MKRIKCFCDKFPSGDTFRMCIILDDYDNRVDYYVGIYDYITSTL
                     MSDIYYRSTIDEHFKIIELIENNPNEIYDDGGGQQFCLEFHHDKVIFYHNEFDEEDGY
                     PVLSCSLHTFKTALIAWNAFLQLPKSIHSVVETVIEE"
     gene            22079..23053
                     /gene="mafB"
                     /locus_tag="ACFOAE_000614"
                     /pseudo
     CDS             22079..23053
                     /gene="mafB"
                     /locus_tag="ACFOAE_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 2"
     gene            23064..23525
                     /locus_tag="ACFOAE_000615"
     CDS             23064..23525
                     /locus_tag="ACFOAE_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884153.1"
                     /translation="MNLETAENIQCEFEYLALDGYFPMHFASHGQGNKDWQFAVEFIY
                     RLLICQLATLEPINFETKNDILDFCHNLAKQSPFNNDNEVWYQGEIVLTKKGIDLIKE
                     YIPEAFEEWNGKKFELNIPFIKTLKNIFVNYEVAWDENNPLFPIISLNLGT"
     gene            23512..23799
                     /locus_tag="ACFOAE_000616"
                     /pseudo
     CDS             23512..23799
                     /locus_tag="ACFOAE_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229180.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EndoU domain-containing protein"
     gene            23826..24245
                     /gene="mafI"
                     /locus_tag="ACFOAE_000617"
     CDS             23826..24245
                     /gene="mafI"
                     /locus_tag="ACFOAE_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MafI"
                     /protein_id="HFC6884154.1"
                     /translation="MYKIKCFYDQFSSGELFNYCQFLDNSSNQKINTRGTVYQYIIYV
                     LTGDLYLQKDIDENLEFIHQAENNPNEVYSGGGQGFCWDISAEKVVFYHNEFDEEDGW
                     PDLSCSLHTFKTALIAWNAFLQLPKSIHSVVETVIEE"
     gene            24335..24406
                     /locus_tag="ACFOAE_000618"
                     /pseudo
     CDS             24335..24406
                     /locus_tag="ACFOAE_000618"
                     /inference="COORDINATES: protein motif:HMM:NF026862.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin type 17 domain-containing
                     protein"
     gene            24403..24645
                     /gene="imm31"
                     /locus_tag="ACFOAE_000619"
     CDS             24403..24645
                     /gene="imm31"
                     /locus_tag="ACFOAE_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Imm31 family immunity protein"
                     /protein_id="HFC6884155.1"
                     /translation="MTNLKLDFYSEVIIKDSCPNDLLENGETIKGKKGVVLGISEEDG
                     IIYGYTILLFDIKYCIYIDKKYIIPTGKKFSRDDFY"
     gene            24723..24968
                     /locus_tag="ACFOAE_000620"
     CDS             24723..24968
                     /locus_tag="ACFOAE_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFC6884156.1"
                     /translation="MKDSTGQMRLATKDLAEAIKRGEVRSSAFTTKQLKAIEKGESKI
                     PDYTWHHHQDTGRMQLVPEWEHSKTGHIGGTAMDKGK"
     gene            24971..25357
                     /locus_tag="ACFOAE_000621"
     CDS             24971..25357
                     /locus_tag="ACFOAE_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884157.1"
                     /translation="MWKIYKENSTDLNFAIGSIYCQAINLTEFKMWVEKIIREVDLDE
                     IPNYFFDLIDFQSLYDLIDIIGFVPENNLSKNQDNALTGIAFLRGIDVYDPPISKEKA
                     LKALKKHPEIYQRFQHFFPFVELPPL"
BASE COUNT         6405 a         5583 c         7030 g         6468 t
ORIGIN      
        1 cagataccga acaccaaaca tcaaatatat atatcaggat aaccaaggga cggcagaagc
       61 taggaatacc ggaataaaaa attcaaacgg aaaatatata gtctttattg attcggatga
      121 ttttattaat tgtcaggtct tgctggattt tcttagtaaa gatgatattg atatgccgga
      181 tgtggttttt ttaaatgcgg ttaaatatga taagggaagt gtttcacatt ttggcgaaga
      241 ttatcagcct gaaaaaatac tcaatcaatc caaagtcgaa gttttgaaag gattatgccg
      301 atttagaaaa tttccgggtt cggcgtgtaa taagattata aaaagggaat tgattatcaa
      361 agaaaaactg ttttttgaaa aagaggttta tgccgaagat atcgaatggt caatgagatt
      421 atttaatgcg gcaacaactt tttcttattt ggacggttgt tattactatt atcggcaggg
      481 aagaaaagat tctaaaacag gaactgtttc ggaaaaaagt ataaagtcat tattatatat
      541 tttggagaaa aatgcggaaa tggaatttaa tagggatata tcaagttatc tttattcctt
      601 tctttcctac gaatatctcg ttttgctttt tatcatgacg agtaaaaata tagagtgtga
      661 tgctgatata aaaagaaggg cgtatcattt aaggtttatg ctgttaaagt ccaataaatt
      721 gatatataag ctgatattcc cgataatcac attattcggg gtcgatatta caggcagaat
      781 tttaaaagta atcagaggga atgtttaata aatcctttaa cactatacat cttaccgaag
      841 gaggaaaaat gaacgcaatc cgaactttcc aaaaccgcac gcccgaaatc cacgaaagct
      901 gtatgataga cgaagcgtgc gtcgtcatcg gcgaagtgtc gcttgccgaa gacgtttccg
      961 tgtggccgtg cgccgtgttg cgcggcgatg tgaacagcat caccgtcggc gcgcgcagca
     1021 atatacagga cggcagcgtc ctgcacgttt cccacaaaac cgccgccaaa cccgaaggat
     1081 cgccgctggt tatcggcgaa gacgttaccg tggggcacaa agtgatgctg cacggctgcc
     1141 gaatcggcaa ccgcgtcttg gtcggtatgg gcagcaccgt tttggacgat gctgtgattg
     1201 aggacgaagt gatgattggc gcgggcagcc tcgttccgcc gcgcaaacgc ttggcgggcg
     1261 gctaccttta tatcggttcg ccggtcagac aagtgcgcgt gctgaccgat gaggaaaaag
     1321 cctttttgaa atattccgcc gcgcattatg tgaagctgtc gaaacagtac gggatgtgaa
     1381 atcacatcgg cgttcttgcg tcagccccaa attcatgcgg acgggatgca tccgataacg
     1441 gtatccgatg cgccttgatt ttgaccgtct gcgtttgagt tgcaggcaaa aatgccgtct
     1501 gaagcccttt tttcgggttt agacggcatt ttatcgccga ttgcttttta cagtttgacc
     1561 gaatgttcgc gcgtttcgtg gaacacgatg tccggccaac gttcttgcgt gagtcccaga
     1621 ttcacgcggt taggggcgag gtaggcgagg ttgccgcccg cgtcgatggc gaggttgccc
     1681 gcgttggctt tttcaaattc cgccagtttt ttcttgtcgt cgcacgatac ccagcgcgcc
     1741 gaccagatgg atgcgctgtc gaacacggct tctacgccgt attcgttggc cagccgcgag
     1801 gtaacgactt caaattgcaa cacgccgacc gcgcccaaaa tcaaatccgc gccgctcatc
     1861 ggtttgaaaa cctgtaccgc gccttcttcg ccgagttgtt gcaaaccttt ttgcagttgc
     1921 ttgattttca gcgggttttt gatgcggacg ctgcggaaca gttcgggcgc gaagaatggg
     1981 atgccggtaa acgtcagttg ttcgccttcg gagaagctgt cgccgatttg gatgttgccg
     2041 tggtttggga taccgataat gtcgccggcg taggcttctt caaccagctc gcggtcgtgg
     2101 gacatgaagg ttaccacgct ggaggcggcg atttcgcggt tgatacgcag gtgtttcatc
     2161 ttcataccgc gctcgaatct gccggagcag acgcgcaaga aggcgatacg gtcgcggtgt
     2221 ttcggatcca tattggcttg gattttaaag ataaatccgg aaaacttagc ctcgtccggc
     2281 tcgaccatac gtacggtcgc gtcgcgcggt ttcggcgcgg gcgcccagtc aattaatgaa
     2341 ttgaggattt cctgaatacc gaagttgtta atcgcagagc cgaagaatac gggcgtgagt
     2401 tcgccggcga ggaattcgtc gagattaaac tcgttcgatg ctgcctgcac caattcgatt
     2461 tcgtcgcgca actgttggat ttccaatgga aagcgttgtt ccaattcggg attttctatg
     2521 cctttgatga tgtcgaactc gtgcggcagg cgttcgccgc ccgcttcaaa gagatagatt
     2581 tcgtcgttca ggatgtggta tacgcctttg aagtttttgc ccataccgat cggccaggtg
     2641 acgggcgcgc agcggatttg caggatgttt tccacttcgt ccagcaattc cagagaatcg
     2701 cgtacttctc ggtcgtattt gttcatgaac gtaacaatcg gcgtatcgcg caggcggcag
     2761 acgtttaaga gcttgatggt ttgcgcttcc acgccttttg ccgcgtcgat gaccatcaac
     2821 gcgctgtcca cggcggtcaa aacgcggtag gtgtcttctg agaaatcttg gtgtcccggc
     2881 gtgtccaaga ggttgacggt gtggtcttta tagtcgaact gcatcacgct tgatgccacg
     2941 gaaatgccgc gctgcttctc gatgtccatc cagtcggaag tggcgaattt gccggttttt
     3001 ttgcctttta ccgtacccgc gctttgaatc gcacctgaaa acagcaagag tttttcagtc
     3061 aacgtggttt tacctgcgtc agggtgggag atgatggcaa acgtgcggcg gcggcgcact
     3121 tggtcgagga tttcttggga catggttttc tttgcaaaaa ggttcaggcc gcttttcaga
     3181 cggcccggac agtgtttgag acggcgaaat tgtacaaaaa aatgcctgat aattcaatgt
     3241 tggaggcggt cagtgcgtgc tgccgtaaat ctctttttcg tctttcagga cggcatcggc
     3301 ggtttcccac gcgctgccac gccagacttt gtaaaagcag ctttctcgcc cggtgtggca
     3361 ggcgatgccg ccgttttggg cgatgagcat cacaatggcg tcgccgtcgc agtcgaggcg
     3421 cagttcgcgg actttttgcg tgtgtcccga ctcttcgccc ttcatccatt gtttttggcg
     3481 cgaacggctg taatagtggg caaagccggt ttcgacggtt ttttgcaggg cttcggcgtt
     3541 catccacgcc accattaaaa tacgtttggt ttcggcatct tgggcgatgg cgcaaaccaa
     3601 acctttttcg tcaaatttga cggcttcaag caggttttta tccatatttc ctttcagacg
     3661 gcatagtcga ggcggtcaga ggcgcacttc gatgccggct tcgcgcatag cgcgtttggc
     3721 ttcgcggatg gcgatttccc cgaaatggaa aacgccggcg gcaagtacgg catcggcttt
     3781 gccttcggtt atgccttcaa tcaggtgccg gacattgccg accccgccgg aggcgatgac
     3841 ggggatgtcg acggcttcgg caacggcgcg ggtcagcggc aggttgaaac cctgtttcgt
     3901 accgtccctg tccataccgg taagcaggat ttcgcccgcg ccgcgttttt gcatttcgat
     3961 cgcccattcc accgcatcca aaccggtcgg attgcgcccg ccgtgggtaa agatttccca
     4021 gcgtgtgttt ccggggttga cggctttggc atcgacggcg gcgacgatgg cttgcgaacc
     4081 gaaaaatccg gcggcttcgt caatcaggtc gggacgggta acggcggcgg tgttgatgct
     4141 gactttgtcc gcgccggcat tgagcaggcg gcggatgtcg gcaacggtgc gtacgccgcc
     4201 gccgacggtc agggggatga agacttgtcc ggcaacctct tcgatgatgt gcaggatggt
     4261 gtcgcggttg tcggatgagg cggtgatgtc gaggaaggtc aattcgtccg cgccttcgcc
     4321 gttgtagcgt ttggcggctt cgacggggtc gcccgcgtcg cgcaaaccga tgaagttcac
     4381 gcctttgacg acgcgcccgt cttttacgtc gagacagggg atgatgcgtt ttgccagtgc
     4441 cataatcgga tgcctttagt cgagggaatc tgccagttgc tgcgcttggg caaaatcgat
     4501 gctgccctcg taaatcgcgc ggccggtaat cgcgcctgct acgccatgtt tttcggcggc
     4561 acacagggcg cggatgtcgt ccaagccggt cagtccgccg gaggcgatga cgggaatgcg
     4621 gacggtttgg gcgagtttga ccgtcgcgtc gatgttcacg ccgctcatca taccgtcgcg
     4681 cccgatgtcg gtgtagatga tgctgttgac gccgtcgtct tcaaagcgtt ttgccaaatc
     4741 aattacatga tgcccggtta cggttgccca gccgtcgatg gcggccatac cgtctttggc
     4801 atccagcccg acaataatcc tgccggggaa ggctttgcac gcctcgcgca cgaagtcggg
     4861 gtttttgacc gccgccgtgc cgataatcac gtcgtttaag cccaaatcca aatattgtcc
     4921 gatggttttc aaatcgcgta tgccgccgcc gagctgtacg gggatgtctt tggcgacagc
     4981 ggcaaggatg tctttgatgg cgggcaggtt ttgcggaacg ccggcaaacg cgccgttcaa
     5041 atctaccaga tgcaggcggc gcgcgccttg tttgaaccag tgcagtgcgg tttcggcggg
     5101 cgaatcggaa aagacggtcg cctcttccat cagcccttgt ctcaggcgga cgcagcgtcc
     5161 ttctttcaaa tcgatggcgg gtatcagcag cataattttt ctccttgtgc ggggccgtgt
     5221 ccggcttacc agtttaaaaa gtttttcaac atcgtcagcc cggcatcgtg gcttttttcg
     5281 gtgtgaaatt gcgtggcgaa tacgttgtct ttgccgacga tgcaggcaaa cggggacggg
     5341 tagtcgcttt cgcccaatat ggtttcggga ttttcggggg cgaaatagta gctgtggacg
     5401 aagtaaaaac gcgtgtcttg gggaatatct ttaaacagcg ggtggttttg ggtttggcgc
     5461 acggtgttcc agcccatatg cgggactttc agacggcatc cctgcgggtc gcggaggtcg
     5521 cgctcaaagc gtctgacttt gccgccgaac cagcccaagc cgtcggtgtt tccttcttca
     5581 ctgtggtcga ataaaagttg cgcgccgacg cagattccga aaaagggttt gttttttaag
     5641 gcatctttga ctgcctcgtc caggccgccg cgcgtcagtg ccgccataca gtcgggcatc
     5701 gcgccctgcc cgggaaaaat gactttgtcg gcgcgggaca cgcgttcggg gtcgccgctt
     5761 aaaaagattt cggtattttt tccggcaagc tgccccgccg tccggacgga tttcaatacg
     5821 gaatgcaggt tgcccatacc gtaatcgata atggcgattt gcatggcttc ctcctctttt
     5881 tttgcaatat ggctgcgatt ttaacaaaca aatgtgccgt gctgataaaa atgccgtctg
     5941 aaaacgggag tctgtcttca gacggcatag ggtttaaacc cggaaagccg tttgtcagcc
     6001 ttccatttgt tttgcctgaa cggcagtcag ggcgatggta aacacgatat cttctaccag
     6061 tgcgccgcgg gagaggtcgt tgaccggttt acgcaggcct tgcagcagcg ggccgacgct
     6121 taagacgttg gcgttgcgtt ggacggcttt ataggtgcag ttgccggtgt tcaggtcggg
     6181 gaagaccaaa acggttgcct gtcctgccac cgggctgccc ggagctttgg atttgcccac
     6241 accctgcacg gttgccgcat catattgcag cgggccgtcg atggcgaggt cggggcgttt
     6301 ttcccgggca agtttggttg cttcgatgac ggtatcgaca tcggggccgc tgccggagtt
     6361 gacggtggag taggaaatca tcgccacttt cgggtcgatg ccgaaggctt ttgcggaatc
     6421 ggcagactgg atggcgatgt cggcaagctg ttgcgcggtc gggttcggat taaccgcgca
     6481 gtcgccgaag acgaggactt ggttgggcag cagcataaag aatacgctgg acacgaggct
     6541 tgcgcccggt gcggttttaa tcagttgcaa agcggggcgg atggtgttgg cggtggtgtg
     6601 aaccgcaccg gataccaaac cgtccacatc attttgcgcc atcatcatcg taccgagtac
     6661 cacggtgtct tgcagttgct tgcgcgcgtc ttcgggtgtc aggcctttgg atttgcgcag
     6721 ttcgcacatc ggctcgacgt attgttcgac caatgaggcg ggatcgatga tttccaaaga
     6781 gtcgggcagg ctgatgccgc gttctttggc aacggcttcg acttcttcgc gtttggcaag
     6841 caggacgcag cgggcaatgc ctttttcgtg gcagatggcg gcggcttgga cggtgcgggg
     6901 ttctgcgccc tcaggcagga cgatgcgttt gtcggcttgg cgggcgaagt cgatcaggtt
     6961 gtagcggaat tgcgccggcg acaggcgttt tgcttcgcgg cctgccaata cggatacgtc
     7021 tttcagcgcg tcgctcgaac cgaagaaggt caggccggtt ttttcggctg ccgcttcggc
     7081 aacggaggct gccgcgccgt ccacgacaaa accttccaat acgcccggcg cggcggcgaa
     7141 gaactgtttg gcaaggttca gccgatttgc cagttcgtcg gcatcggcgt tgtcggaacg
     7201 gacggcgaag acggctgccg cgtcaaggga caatgccagt tcgacgtttt tgcctgcgag
     7261 gtagattttg tcggcatcgg gcgcgatgcc ttcgatgacg aggttggcgg catcgagtgc
     7321 ggcaactttg ccgaccagtg cgtcgaacca gtcgtcgctt ttgccttgcg cgagcagggt
     7381 ttcggcggtt gcgtcaacgg cttggaaaat ttgtgcgtcc agtgcttttg caaaggcttg
     7441 tgcggcggcg gaggcgtcca gtccggcaga tacgggtacg atgagtactt ttgccatgat
     7501 atatcctttc gtatgctgcg gtgtgcggca tatgtggttg gaaggggcgg catataggca
     7561 gaaacggctg cctgcgtgcc gtgcgtgccg tgtttggctt gaggcgcgca ggttgaatat
     7621 agcaaacaaa ttctgtttcc aacaagataa atatccgcag gtttgtggat gctgccgcct
     7681 ttcagagggt atttccgggg aagaacaggg cgggaccgtc caaatggagg acggcggaaa
     7741 tgccgtctga cagggtgggg gcggaaggga ggttgagcgt gaggacggtt tgtccgaccc
     7801 ggagactgat ttcggtatgc cgcgctttgg gcgtggtttt gagaaccacg gcgtgaatgg
     7861 aggcggtggg tgcggaatgg gggtgaaggc tgaactgttc cggacggatg agcagtgtgc
     7921 cgcgtgtgcc tgcgggtgcg ccgctttgaa cgggcaggcg gcccaatccg caatcggcgg
     7981 tgccgtcggc gttgagcgcg gcggggaaca cgatgccttc gccgataaac agggcggcat
     8041 caaggtcggc aggttgtcgg tacaattcgt gagggcttgc agtttggagg atgcgcccct
     8101 gtttcatcac ggcaatccgg tcggcgtatt gcagggcttc ttcgcggtcg tggctgacga
     8161 aaacggcaga tttgccgttg gcgcgcaggg cggcaatcat gtcttcgcga atctggcggc
     8221 gcaactgttc gtccagcgcg ctgaagggtt cgtccaacaa aatcagttcg ggatcgggtg
     8281 cgagggcgcg ggcgagggcg acgcgctgtt gctgtccgcc cgaaagttcg tgcggatagc
     8341 gtccggcaag ttcggaaatg ccggtcaatt ccaacatagc ttcgatgcgc tgccgctctt
     8401 gcgccgtctt gcctttgccg ttgcccagcc cgtaggcggt gttgcggtaa acggtcaggt
     8461 gggggaacag cacaccttcc tgtacgacat aacccaaacg gcgttcgcgg acggggaggt
     8521 tggtattttt cgagaagatg gttctgccgg aaagcgaaat ttcgccaaaa tcgggttgtt
     8581 caaaaccggc aaggcagcgt aaaagggtgg ttttgccgca gccggacgcg ccgacgataa
     8641 agaggatttc gcccgggtcg aggctgagcg aaatgtcgtt taaaactggg gtgttttgaa
     8701 aacttttgga caggtgtccg atgtgcaggg cggcggtcat ggcggtactt cctcaagctg
     8761 ttatttgaag gcgtatttct tcagcaggaa tacggggatg ccggaaaata ataccagcat
     8821 cagcgcgtaa ggggtggcgg cggcgtattg tgcgtccgat gtgtattccc aaacggcggt
     8881 ggagagtgtg tggacatcgt cggtggtcag cagcagggtg gcggtcagct ctttcatcag
     8941 tttgaggaag acgagtgcga atgcggcggt aatgccgggc aggatggacg gcagtaccaa
     9001 cgtcctgaaa ataaagaagt gtccgcgccc caatgttgcg ccgacctgtt ccatcccttt
     9061 ggggagttgt tccaaggaag tcctcagggt ggtttgcgcc atcggcaggt aaagcatgaa
     9121 ataggcaagg atgacgacga taaaggtttg gtaaacggca ggggtgtagt tgatgctgaa
     9181 ataaaccaag gatagggcga taaccaaacc ggggacggcg tgcagtaaaa acggcagcct
     9241 gtctatccaa acggttaaaa aattgcgata gcgaaccgat gcccaaacaa ggggcaaggc
     9301 acataatata gtcaaaatcg cacctaaagc cgatacgctt aaggaacgga taaaggcatc
     9361 aaatacggat acgagcgcga atgtgccgga agtgccgacc atcatccaat gtatcaatac
     9421 gccaaagggg ataataatgc ccaaagtcaa caagctgctt aaaaaaacaa tcgcgccgat
     9481 ctgaccgggc agtttgaggg ttttgacggg ataaggacgg gcaacgcctt tgccgctgtg
     9541 gtaaatcttg gctttgccgc gaaatatgct ttctccaaat acgacgatgc cgcacaccgc
     9601 cattaaaaca gcggaaagca gggcggcggt attgttgttg taggacattt cgtattcttg
     9661 gaaaatggcg gtggtaaaag tggggtagtt caaaatagat accgcgccaa attcgaccag
     9721 catatgcagg gcaatcagta acacgctgct gccgatggcg ggtttgagct gggggaggat
     9781 ggcggaaaaa aaggtttgca ggcggctttt gcccaaggac aggctgactt cttcgtaaga
     9841 caggctgatg cgtttgagtg ccgcctcgac gggcaggtag gcgagcggga acgaggacag
     9901 gctcataatc atcactgtcc cccaaaagcc ttcgacacgg aaggtcaggc tgatccaggt
     9961 gaaacagctg acaaatgcgg ggatgcacaa aggcagggtg attgccgtct gaaaaaaggt
    10021 tttgccgaag aagcggtaac gttggaacaa aagggcgcag gcaatgccca aaacaatgga
    10081 aatcagggta acgcccgcca tcatcgtcaa ggtgttggag agcaaatccc acatacgcgg
    10141 gcggaacaac agttcgacgg cgcggttgat gccgacctgc cacgaacgca tagcgacata
    10201 taaaaaaggc agggtaagcg gtagggcaat cagtaggatg aggccggtaa gccaaatggg
    10261 tattttttta ggagacatag tgttttttat cggcaaaacg ggcggacagt ataaatgtcc
    10321 acccgtttga caatccgaaa acggcttatt tcataccggc ttgctcaagc agccgggtgg
    10381 cgtgttcttt ttcggaaaca gtggtggcgg acacttgggg tgcttccaac ttggcgatgg
    10441 gttccaaatt gaaggtggat accacgtgcg gattcaaagg atactcggca cggacggcgg
    10501 tcagggcacg ctgtccttcc ttgccggcga ggaaggcgac gaattttttc gcctcatcct
    10561 tgttttggga ggattttaac acggctgcac cggaataggt aatgagtgcg ccgggatctc
    10621 tgtggcggac gaaattcagg cgggtgtgga cgttttgtac gcctttttca cgcgcgaaag
    10681 cgtgccagta gtagttgttg atgagggcgg catcgatttc gccgttttca accgcttgaa
    10741 gggcgacgga gtttttagcg taaggcttgc cgtattcttt cagacctttg agccatttca
    10801 atgcggccgc ttcgcctttc agtttgacga tggcgacaac ctgttccaag aacgcgccgg
    10861 aagtgggggc gtaaccgatg cggtttttcc atttcggcgt ggcgtaattc aggacggatt
    10921 tttctaaatc tttttcagac agtttgcggg tgtcgtaaac gacgacgcgc gaacgtccgc
    10981 tcagtgccac ccagtctttt ttggcggcaa ccggcacgcc cttgccgcgt gtttcgttga
    11041 tggtggaggc gggcaggggc tctaggaggt tggctgcgga aagggtggcg agtgccggga
    11101 tttgttcgga atagaatacg tcggcggggc ttcggctgcc ttcttctttg atttgaccgg
    11161 caagctggtc gcctttggcg ctgttgagtt tgactttgat gccggtagcc cgggtaaagg
    11221 catctgcaac ggcttgtgct gcttctttgt gttggccgtt gtacacggta atgtctgcca
    11281 gcgcgggggt tgcggcggtc agggctgcgg caagcagtgc gtatcggata gatgttttca
    11341 tatcgatttt ctcctaatga atgagagtgt acaccttgtt aagacataac ggtgtgtagt
    11401 gtattccttc ttctttataa atgcaaataa ttatttttta aatttgttat tatccgatcc
    11461 ggttattgtt tgttctgact tgtatttttt ccgtgcatcg cgcccgtaag gcggaagcgg
    11521 cgggcaatgc gtggcggaat gtgggtaaag gcggcatttt gatttgtcgg aatgcttgag
    11581 aacccctctc tttaaaacag cgtctgaaca gggttgccgg aatagtattg ccatcccggc
    11641 agatacagtt tgtcggggtc ttgccaatat tgttcatcca gactgttcag cagtgaggcg
    11701 gttttgttgt cgagatgtta tatcccacat ttctttcagg tttttacctt ccgattggag
    11761 gcggcggatt tcttttctca atgcgtctgc cgcccgatgg atcagcattg cgctgtgtat
    11821 cgcgccgatt tttttcagaa cggaactagt cttttcggcg gcgggaaaac accagttgca
    11881 gacaaattgc agtatgccgc cgttaccgat gtcggcttcc gcccgccaaa tcaaaaccag
    11941 ctcctgttcc cgtccgtcca tgctttcgag tttgccgtta tgctgttcaa aaagtttgtc
    12001 caccgcctgc cacatcatct gctcgaagcg gtcggcttgg gtatccgtat cggtcatcgt
    12061 gttcttgcct tttaaaaatg ccgtctgaac atttcttcag acggcatcgg gggttaagcc
    12121 aacacttcac gccagcgttt gacttggagg cgtacctgtt cgggcgcggt gccgcccaag
    12181 tggttgcggg cgtttaagct gccttcgggt gtcagtacgc cgtacacgtc gtctgaaatc
    12241 agcttgctga agccttgtaa gacttcaagc ggcagttcgc tcaaatcaac gccagcttca
    12301 tcggcatggc gcacggcttg ggcgacgact tcgtgggcat cgcggaaggg catacctttt
    12361 ttaaccagat aatccgccaa gtcggtggcg gtggcaaaac cctgcatcac ggcggcgcgc
    12421 atattgtcgg gtttgacggt tacgccgcgc atcatatcgg cgtaaatccg cagcgtgtcg
    12481 atgagcgtgt cggcggtgtc aaacaaaggt tctttgtctt cctgattgtc tttgttgtac
    12541 gccaagggct gggatttcat cagggtaatc aggccgataa ggtgtccgat gacgcgtccg
    12601 gatttgccgc gcacgagttc gggcacgtcg ggatttttct tctgcggcat gatggacgaa
    12661 cctgtgcaga aacggtcggc gatgtcgata aagccgaaac gcggactcat ccacaaaatc
    12721 aattcttcgg acaggcggct caggtgaacc ataatcagcg aggcggcggc ggtgaactcg
    12781 acggcaaaat cgcggtcgga tacggcatcg agcgagtttt ggcagatttg ctcgaaaccc
    12841 agtaattcgg cggtaatttc gcgccgaatc gggtaggtcg taccggcaag ggcggctgcg
    12901 ccgagcggca tacggttgac gcggcggcgg cagtccgcca tccgttcgtt atcgcggccg
    12961 agcatttcga cgtaggcgag catatggtgt ccgaagctga cgggctgggc gacttgcagg
    13021 tgggtaaagc caggcataac ggtttcggcg ttttgttccg ccaaatccag caatgccgtc
    13081 tgaaggtttt gaatcaggtt ttgaataacg gtaatctggt cgcgcagcca caggcggatg
    13141 tcggtggcga cttggtcgtt gcggctgcgg ccggtgtgca ggcgtttgcc cgcgtcgccg
    13201 attttgtcgg tcaggcggcg ttcgatgttc atgtggacat cttccaaatc ggacgaccat
    13261 tcgattttgc cgctgcggat ttcttcgagg atttccgcca tgccctgacg gatgtccgcc
    13321 aaatcgcctt cgtccaacac gccggtttct ttcaacattt gcgcgtgtgc cagcgagcct
    13381 tggatgtccc attcggcaag ccgtcggtcg aaaccgatgg aggcggtgta ttgtttgacg
    13441 agttcggaaa cgggttcgtt gaaacgtccg gaccaggttt tgtcgtgcat aaggattcct
    13501 tgatggggtt attcggtacg gtatttttcc aaaaggcggc ggaagggttc gccggtttcg
    13561 gggtgtttca ggccgtaggc gacggtggct tcgaggtagc ccagtttgct gccgcagtcg
    13621 tagcgcgtgc cttcaaaggg gtgcgccagg acaaattcgt gatcgagcag cttggcgatg
    13681 ccgtctgtaa gctggatttc gttgcccgcg ccgcgcggaa gattggttaa gaggtcgaaa
    13741 atgcgcgggg taaggatgta gcgtccgacg acggcaaggt tggagggcgc gtcttcgggc
    13801 ttgggttttt cgacaatgcc ggtaatgcgt tggaactgtt tgagctgttc ggtttcgacg
    13861 atgccgtatg agccggtttg cgacggttcg acggtttcta cgcccaaaat gctgttgccg
    13921 ctgcgttcgt acacttcgac catttgtttg agcgcgcctt ttggggcatc gattaaatcg
    13981 tcagccaaaa tcacggcgaa gggttcgtct ccgatggcgg cgcgggcgca caagacggcg
    14041 tgtcccaagc ccagtgcttc cgcctgacgg atgtagaggc aggtaatgtt cggtggcagg
    14101 atgttgcgga cgtgttccag aagtttgtct ttatggcgca tttccaactc ggtttcgagt
    14161 tcgtatgcct tgtcgaaatg gtcttcgatg ctgcgtttgt tgcgtccggt aacaaacacc
    14221 atttccgtgc agccggcttc cacggcttct tctacggcgt attggatcag cggcttgtcg
    14281 acgatgggca gcatttcttt cgggcttgcc ttggtggcgg gcaggaagcg ggttcccatc
    14341 cctgcgacgg ggaagacggc tttttttatc ggtttcattc tttttccttt gtattgtttt
    14401 gatgtttaaa gggcgagttt gcggattaaa tcggcgagtg cctgcgcgcg gtggctttcg
    14461 cggtttttga cctccgaatc caattcggcg gcggttttac cgtgtccggg cagataaaaa
    14521 tacgggtcgt aaccgaaacc gttttcaccg gcgggaacgc cgttccattg tccgtgccat
    14581 acgccttcgg caataatcgg acgcgggtcg tctttatggc ggacaaaaac caatacgcag
    14641 acgtagcaac agcttttgtc ggctttgccg acaagttcgg cggcaagttt caggttgttg
    14701 gcggtatcgg atttgggatt gtcgcccgcg taacgtgcgg aatggatgcc cggcgcgccg
    14761 tttagggcgg cggcacagat gccgctgtcg tcggcgagtg cgggcagccc gctgtgtccg
    14821 gcggcgtgcc gggcttttgc cagcgcattt tcaacaaagg tggaataggg ttcggggcat
    14881 tcgggtatgc tgaactcgga ttgcggcaat acggtaatgc cgtatggttc gaataggttg
    14941 ccgaattctt tgagtttgcc tgcattgccg cttgccaaaa cgattttttc cggtttttca
    15001 gacatagcgg ttttcctttg cggcggattg ggcggcgcgt agggatttgt gccgcaggta
    15061 gagggcgagg ctgccgattt gtccgaacag tgcgccgaat gcgaaaagaa aggaggcgac
    15121 ggcgaaggct ttgctgccga cggtcagcag ataagcaccc aagaggacga gcagcataaa
    15181 tgccagtgtg aagagggcaa cagacaacag atagattttt cggcggttca tggcgttcgg
    15241 tcggaaacgg tatgttcgga ttatagccga ttgggacggt attccctaga gcttggaaaa
    15301 atgccgtctg aaacggcgtt cagacggcat ggcgggcgtt atgcctgttt gttccaacgt
    15361 tcgatggatt ctttgatgac ttttttcgct tcttccgcat cgccccacga ttcgactttg
    15421 gtcgtacctg cttttttcag gtctttgtaa tggttgaagt ggaactcgat ttgtttgatg
    15481 agctgttgcg gcaaatcgga caaagttttg taggcgttgc cgttgttgcg gtcgtcggca
    15541 ggaacgcaga cgattttgtc gtccacttcg ccgtcgtcaa cgaatttcat cacgccgata
    15601 acgcgcgctt ccaagaatac gccggttgcc aaaggttgtt cggtaacgag cagcacgtcc
    15661 aattcgtcgc cgtcttcgtc caaagtttgg ggaatgaagc cgtagttggt cggtttggcg
    15721 aagatggcgg gttcgacgcg gtcgagttgg aatgcggcca gtttgcggtt ccattcgatt
    15781 ttgtggttgc tgccggcggg gatttcgttg acaacgttga tgatgccgcc gtccacgtcg
    15841 ccgggggtca ggatttggtt gaagtctgcc atttggtttc ctttgtttgg gaaagtgtga
    15901 agtttgaaag tatagcacaa acgtccggct gaaaatgcgc ccgatgcctc tgaaagggtg
    15961 tacgggcgcg tgttaccgtt tgcccaaaaa cctgcccagt tccaaaatcg cgcgcctgtt
    16021 ggacggggaa aatacttttt ccgctgcttc ttccatatcg aaccaaccgt aggagacgtg
    16081 ttcttcgggt tgcagggcga tgggcgtatc acgcgggatt tcggcagaga agaggtgttc
    16141 gcggttttca aacacgcctt ttggatagcg gtgccgccag tggtggtaga tttcgtaaac
    16201 cgtgctgtcg tgccagtctt gaagctgccc gtccgccagc aggatgccgg tttcttccca
    16261 aacttcgcgc cttgccgttt gggcgacggt ttcgcccggt tcgaggctgc cggttaccga
    16321 ctgccaaaat ccttccggat gcgtgcgttc gatgagcagg atgccgccgt ccccgctata
    16381 aaggacgacc agtgcggaaa cggggtattt gagcggtttt gccatcggca tctttcggcg
    16441 ggctgcggta atgaaggggc ggattatagc aaacgccgca cgttatggcg tttatccttt
    16501 tccgtatcct tttttctgca cggatgggac gcgccggtgt ttgccggtaa attttccgtt
    16561 gtgtcaaaaa gataagggcg gttgtgattt taatgcttgc caaagcgtcg ggcggaaact
    16621 ataatccgaa acttatcgag tcggagtgtg gcgcagtctg gtagcgcact tgcatggggt
    16681 gcaaggggtc gaaggttcga atcctttcac tccgaccaaa aattccgaaa gccgctttca
    16741 aaagcggctt ttttgccgtc cgtatgatta tgatgtagag tacgcggcga cagacattca
    16801 aatgccgtct gaaaaccgtt cagatggcat ctctttatct tagtttcatt ccgtaccatc
    16861 ttaaggaaca tcaaattggg catttcccgc aaaatatccc ttattctgtc catactggca
    16921 gtgtgcctgc cgatgcatgc acacgcctca gatttggcaa acgattcttt tatccggcag
    16981 gttctcgacc gtcagcattt cgaacccgac gggaaatacc acctattcgg cagcaggggg
    17041 gaacttgccg agcgcagcgg ccatatcgga ttgggaaaaa tacaaagcca tcagttgggc
    17101 aacctgatga ttcaacaggc ggccattaaa ggaaatatcg gctacattgt ccgcttttcc
    17161 gatcacgggc acgaagtcca ttcccccttc gacaaccatg cctcacattc cgattctgat
    17221 gaagccggta gtcccgttga cggatttagc ctttaccgca tccattggga cggatacgaa
    17281 caccatcccg ccgacggcta tgacgggcca cagggcggcg gctatcccgc tcccaaaggc
    17341 gcgagggata tatacagcta cgacataaaa ggcgttgccc aaaatatccg cctcaacctg
    17401 accgacaacc gcagcaccgg acaacggctt gccgaccgtt tccacaatgc cggtagtatg
    17461 ctgacgcaag gagtaggcga cggattcaaa cgcgccaccc gatacagccc cgagctggac
    17521 agatcgggca atgccgccga agccttcaac ggcactgcag atatcgtcaa aaacatcatc
    17581 ggcgcggcag gagaaattgt cggcgcaggc gatgccgtgc agggtataag cgaaggctca
    17641 aacattgctg tcatgcacgg cttgggtctg ctttccaccg aaaacaagat ggcgcgcatc
    17701 aacgatttgg cagatatggc gcaactcaaa gactatgccg cagcagccat ccgcgattgg
    17761 gcagtccaaa accccaatgc cgcacaaggc atagaagccg tcagcaatat ctttatggca
    17821 gccatcccca tcaaagggat tggagctgtt cggggaaaat acggcttggg cggcatcacg
    17881 gcacatccta tcaagcggtc gcagatgggc gcgatcgcat tgccgaaagg gaaatccgcc
    17941 gtcagcgaca attttgccga tgcggcatac gccaaatacc cgtcccctta ccattcccga
    18001 aatatccgtt caaacttgga gcagcgttac ggcaaagaaa acatcacctc ctcaaccgtg
    18061 ccgccgtcaa acggcaaaaa tgtcaaactg gcagaccaac gccacccgaa gacaggcgta
    18121 ccgtttgacg gtaaagggtt tccgaatttt gagaagcacg tgaaatatga tacgaagctc
    18181 gatattcaag aattatcggg gggcggtata cctaaggcta agcctgtgtc tgatgcaaaa
    18241 ccgagatggg aggttgatag gaagcttaat aaattgacaa ctcgtgagca ggtggagaaa
    18301 aatgttcagg aaataagaaa cggaaataaa aacagcaact ttaaccaaca tgctcaaata
    18361 gaaaaagaaa ttaagaaatt aagcagggat ccatctgggc taatcggaaa agaatttgaa
    18421 gattggttag ttaaatttca tggaggaaat ggaagcttta aaatgggagg gagagagttt
    18481 gatggtgcta ttacaatcaa tcgttggtat gaagccaaat ctggtaattt ctggagagat
    18541 catacttcta cacctcaaaa attcgaaaaa tttaaatcag atatgggtca tagactgaaa
    18601 attgcaacag aaaatggggc aacatatgaa ttacattcaa atacaccaat tcccaaacat
    18661 gttaaagaat ttttgaacaa aaaaggtatt aaatattttg aatattaaaa gttataggag
    18721 atttaaaaat gtcaagaaat gtaagtttgg atattgattt atccatgaat aataaaaaat
    18781 tttctcgtta tgaaatacta gaatgcttat tgtatggagg ttggagtttt ctagatgatg
    18841 gaaattttgt ttacttacca cttggtgatg aagactatga ttggaattca gcttctatgt
    18901 cagaaaaaga aattttagat tttttaagaa taaaaagtaa tttagatgaa gtaatcggat
    18961 tttcaataac atgggctgac accaatattg gtggacaagt tttatttttc cctaattttg
    19021 aattctcatt tagcatcact attaatatta aaaattttga taaagacata gttgatgtta
    19081 actggtattt gattaaatta ttacctatat ttgataagaa tggtatttta tataattcta
    19141 ttagatatca ggaatataga taaatcataa attagcaagc cgtagcccat atgaaaccta
    19201 aactcaacaa gtaggatgtg tgcggaacgc acgcatgcgg ttctctaaga ggccgtctga
    19261 aacaacaaat acctttcttt taataagttg tcacagcaat cagacaaaag cagcctacct
    19321 ccacatccat ataggcaaca taggggagat attttgtaaa ttctacaaat attttacctg
    19381 ctaaacaggg taggatatgg tatgaagcga acattggctt aataaacact atgtcaagat
    19441 cgaatcagac tggtactaga ttattatatt ctaacgatgg attgctatat ataacaactg
    19501 atcattatat ctctgcaata caaattggaa cttggaaata ggagtataac ttatgcaatt
    19561 agagattatc ggtagtaaaa tttatacgga acaagatttt cataatcaaa tttcaaaaat
    19621 attttctata caagattatt atgggaacaa tcttgatgct ttatgggatt tattaagcac
    19681 aaatgtagaa cgaccgatta ctttggtatg gaaagatgct atgttctcaa aaaatcaatt
    19741 agaaaatata tttattgaaa tcgtaaatgt tctagaaaga gttaagaaac aagatgagga
    19801 ttatggattc gaagaaaaat ttaattatat tttagagtaa gtaaacccta attacattac
    19861 gtacacaggc ttaaaactcc ccagagccaa ttaagcaagc cgtaacccat ataaaactta
    19921 aactcaacaa gtagcatgtg tgcggaacgt acgcatgcgg ttcttaaagt ttgagctaag
    19981 aggccgtcta aaaacagaaa aaccgtttca gacggtcttt gtttaacgcc accgatccag
    20041 cgggttacaa agcgcagtca atgccgctgc gccttatgcc tccgaagcaa taggcagaac
    20101 atttggacac ggtgaaaaca aaaacgaaac cgcccaagcc gtcggacatt tccttttagg
    20161 agcagctatt gcccgcgtca acggtggtaa ttttgctgcc ggcggctcgg cagcagttgc
    20221 agctgaaaag gcggcggaac atcttgccca acagtataac gacggtaaaa ccgcaatcga
    20281 tccgcaaaca ggcgagttca atgccaacct gctgccggaa catatcaaag aggaaatcaa
    20341 atcaaagagc ggggtgattg catcgctgac gggcgcggcc gtgggcggca cgccggtaga
    20401 tgcgcaaacc ggaggtgcgg tcggacagaa tgcggtggaa aacaacctct atctgacatc
    20461 ggaagcctta aagaaggaca agcagacagc tcgtaaaatt tattccgtca taaaagagca
    20521 agtcaagcat gaatgcagtt ccacaggaag aattaccgaa tgtcgtcaaa atataggacg
    20581 cattatcgaa tttacccaag acaaacgctt tgacagtagg tttaaggact taaaaaaaga
    20641 atccttatat tacctaaata aacatcctga tttagtagcc tcttatttga aggctgaata
    20701 cgaaaagctg gatagggaag acaaaagtat cctgcaccgc tacatctcac ccggggctga
    20761 aatcgtttcg ggcagtttgg gggttgttct ttcaggagta gccggaggcg gatcttgtgc
    20821 cgagactttc ggcttaggct gtgccgccgc tttggttggt gtaacgtctt cctacgatca
    20881 tgtcattact gggacgaaaa acttcggaaa aaaagccagc gagcaacgac cgacgattgc
    20941 ggttcaggcc ttgaagcagt tggggctgtc ggagcaggct gcggaatatg ttcagttctc
    21001 tatagatttg ttcagtgtgg gtaaatcggg gggcggtata cctaaggcta agcctgtgtt
    21061 tgatgcgaaa ccgagatggg aggttgatag gaagcttaat aaattgacaa ctcgtgagca
    21121 ggtggagaaa aatgttcagg aaacgagaag aaggagtcag agtagtcagt ttaaagccca
    21181 tgcgcaacga gaatgggaaa ataaaacagg gttagatttt aatcatttta taggtggtga
    21241 tatcaataag aaaggcacag taacaggagg gcatagtcta acccgtggtg atgtacgggt
    21301 gatacaacaa acctcggcac ctgataaaca tggggtttat caagcgacag tggaaattaa
    21361 aaagcctgat ggaagttggg aggtgaaaac gaaaaaaggt gggaaagtga tgaccaagca
    21421 caccatgttc ccaaaagatt gggatgaggc tagaattagg gctgaagtta cttcggcttg
    21481 ggaaagtaga ataatgctta aggataataa atggcagggt acaagtaaat cgggtattaa
    21541 aatagaagga tttaccgaac ctaatagaac agcatatccc atttatgaat agtaatattt
    21601 atgaaaaatt aggagattaa tgatgaaaag aattaagtgc ttttgtgata aatttccatc
    21661 aggagataca tttagaatgt gtatcattct ggatgactat gataataggg ttgattatta
    21721 tgtaggaata tatgattaca ttacgtctac cttaatgagc gatatttact atcgatccac
    21781 gattgatgag catttcaaga ttatagaatt aatagaaaat aatccaaatg aaatttatga
    21841 tgatggcggt ggtcaacaat tttgcctaga atttcatcat gataaggtca ttttttatca
    21901 caatgaattt gatgaagaag atggttatcc agtattaagc tgttcgctgc atacttttaa
    21961 aactgcttta attgcttgga atgctttttt gcaattgcct aaaagtattc attcggtggt
    22021 ggagactgtg attgaggaat aagcataatt agcttaatga atagaatcag cgatatagaa
    22081 aggtagaatc agatatatcc cacctaaaaa ttactctcct tcagcaccgc taccaaaagg
    22141 acctaataat ggatatagtg ccgggaattt aagcaaaaaa gtcctgactt tagtttacat
    22201 aaacggcaaa ctcaaattcg ggccaagcag tctgccgtct tcggcattga aagcacctgt
    22261 tcccattgtc ggcaaggctg aggctccgcc cggaaaagct gtgcctgtcg gcgaagcccg
    22321 cattccttca aatccaaaag cggtaaaagg aacaaccgtt accctgtcgc aggaacaacg
    22381 cctagccaac ggagagctga taccgaaagg ctctgtggta acgtggtcgg acaatgcggt
    22441 gaaggttgtg cggcctgatg ggaaaaagcg gagatttaat agtcgggatt gggaacagaa
    22501 ggcattgccg aaaccgcaac taccgaaaga ttacagagat gacatcaaca taggtggaaa
    22561 taatcctaga tttaatcagc aacggcatga aaaaatcgaa tcccacaacc caaacagaat
    22621 agaggagata cgccaacgta atgccgtttc ttctgcagaa aggcaggctg atgcattaaa
    22681 aaggatgcaa acgtctggcc gcacccgcct gcctgggcag ccacaaaaag gaaaacccgg
    22741 cgctgctaga gaaatgtcct cttcagacaa tccgaatcaa acagccgagg cttttgcacg
    22801 tcgatattta ggcaggaaac ctacactaat ggaacgagtc gaaggtgaaa aattatacgg
    22861 aggtaaatgt gtgggctgtt ggaaagcgca aatgccggac ggaacctttg tggtgtatag
    22921 gccagcaggt aatgcttcta tgaccaaggg aactactgcg tctgttgata ttaataaccc
    22981 aacattaaat aacttaaata ttaatttaaa aggcaagcca acagagttaa aatttaaatt
    23041 ccctgctaga taaggatgtt ttaatgaatt tagagacagc agaaaatatt caatgcgaat
    23101 ttgagtattt agcattagat ggttattttc caatgcattt tgcatcgcat ggtcaaggaa
    23161 acaaagattg gcaatttgca gttgaattca tatatagatt attaatatgt caattagcaa
    23221 ctcttgaacc tatcaacttt gaaacgaaaa atgatatttt agacttttgc cataatttag
    23281 caaaacaaag tccttttaat aatgataatg aggtgtggta tcagggggaa attgtattaa
    23341 caaaaaaagg gatagattta ataaaggaat atattccaga ggcgtttgaa gagtggaatg
    23401 gaaagaaatt tgaattaaac attcctttca ttaaaacatt aaaaaatata tttgttaatt
    23461 atgaggtagc atgggatgag aataatccac tattccccat tatatcttta aacctcggca
    23521 cctgataaac atggggttta tcaagcgaca gtggaaatta aaaagcctga tggaagttgg
    23581 gaaatgaaaa aaggaagggg cggaaaacct atgacaaatc attctatgtt cccaaaagat
    23641 tgggatgagg ctagaattag ggctgaagtt acttcggctt gggagaaaag aaaggaatta
    23701 gaaggtcaaa aatggagagg tacaagtaaa tctggtgttg aaatagaagg atttacggaa
    23761 cctaatcgaa cagcttatcc actttataat agtaaatgaa gtattgatta aaaaggtgtt
    23821 tttaaatgta taaaataaaa tgtttttatg atcagtttag ttctggtgaa ttatttaact
    23881 actgccagtt tttagataat tcttctaatc aaaagataaa tacacgagga acggtgtatc
    23941 aatatattat ttatgtttta acaggagacc tttatctaca aaaagacata gatgaaaatt
    24001 tagaatttat ccatcaagca gaaaataatc ccaatgaagt ttattcagga ggtggacaag
    24061 gtttttgctg ggatatttct gctgaaaaag tagttttcta tcacaacgaa tttgatgaag
    24121 aagacggctg gcctgattta agctgttcgc tgcatacttt taaaactgct ttaattgctt
    24181 ggaatgcttt tttgcaattg cctaaaagta ttcattcggt ggtggagact gtgattgagg
    24241 aataagcata attagcttaa tgaatagaat cagcgatata gattggactg caaatccacg
    24301 cttatacgct gtgccatgat taacaggaag agagcaactt ggatgggcta gtagggatgg
    24361 taagcattta aatatatcaa ttgatggaaa gattacacac aaatgactaa tttaaaatta
    24421 gatttctact ctgaagttat tataaaagat tcttgcccta atgatttgtt agaaaatggt
    24481 gagactatta aaggaaaaaa aggagtggta ttaggtataa gcgaagaaga tggtataatc
    24541 tatggctata ctattttact ttttgatata aaatattgta tatatataga taagaaatat
    24601 attataccga ctggaaaaaa attctctcgc gatgattttt attagctaat ttaagtaatt
    24661 taagcaagtt ttttagatac tgaaactggt aattatgttt atgtaagcat aaggagttca
    24721 gattgaagga ttctacaggg caaatgaggc tggcaaccaa ggatttggcg gaagccatta
    24781 aacgaggaga agtacgtagt tctgctttta caacaaagca actaaaggca atcgaaaaag
    24841 gagaatctaa aataccggat tacacttggc atcatcatca agatacaggg agaatgcagc
    24901 ttgtacctga atgggaacat tctaaaaccg gtcacatagg agggacggca atggataaag
    24961 gtaaatgatt atgtggaaaa tttataaaga aaatagcacc gacttaaatt ttgccatagg
    25021 cagtatatat tgccaagcaa tcaatcttac cgaatttaaa atgtgggtcg aaaaaatcat
    25081 aagggaagtg gatttagatg aaattccaaa ttattttttt gatttgatag attttcaatc
    25141 actatacgat ctgattgata ttataggatt tgttcccgaa aataacttat caaaaaatca
    25201 ggataatgca ttaaccggta ttgctttttt aagggggata gatgtctacg atcctcccat
    25261 ttcaaaagaa aaagcattaa aagccttaaa gaaacatcct gaaatttatc agaggtttca
    25321 gcatttcttt ccgtttgtag aactgccccc gctttaaaca gtcaaaatgc cgtctgaaag
    25381 ccatttccgc cgctcagacg gcattttcgc cccttttgtt tacaaaccct taaaatccat
    25441 ttatactcaa aatccgttca aaacaaaaca aaccctgcca tgaaaa
//
LOCUS       DAXIDM010000018        24731 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000018 DAXIDM010000000
VERSION     DAXIDM010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 24731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24731
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.018"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            59..1132
                     /locus_tag="ACFOAE_000622"
     CDS             59..1132
                     /locus_tag="ACFOAE_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HFC6884158.1"
                     /translation="MRPFFVGAAVLAILGALVFFISPGAVVLHRQIFLELMLPAAYGG
                     FLTAALLDWTGFSGNLKPVATLMAALLLAASAILPFSPQTASFFVAAYWLVLLLFCAR
                     LIWLDRNTDNFALLMLLAAFTVFQTAYAVSGDLNLLRAQVHLNMAAVMFVSVRVSILL
                     GAEALKECRLKDPVFIPNVVYKNIAITFLLLHAAAELWLSAQTAGFTSLAVGFILLAK
                     LRELHHHELLRKHYVRTYYLLQLFAAAGYLWTGAAKLQNLPASAPLHLITLGGMMGSV
                     MMVWLTAGLWHSGFTKLDYPKLCRIAVLLLFMAAVSRAFLMNVNPIFFITVPAILTAA
                     VFVLYLLTFVPIFRANAFTDDPE"
     gene            complement(1178..3367)
                     /locus_tag="ACFOAE_000623"
     CDS             complement(1178..3367)
                     /locus_tag="ACFOAE_000623"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFC6884159.1"
                     /translation="MIYHRIAVNVPLSDGLLTYSHSEPLPQGMRVLVPFRNKTVVGMV
                     WETDIAPDMDTARILSIQTTFLDAPPLPESWRDLLSFTSRYYHYPTGQAVFAALPQGL
                     KETRAVEMPQPPLFYALNEAGRAQTPPPARFNKKAALWDALLSGEMTMAALKQVNAQA
                     VKLIENWAEQGWIETTEAAKPVLRSCNGQASHSEFVLNADQQKASDAIQTALGRFQPF
                     LLYGITGSGKTEVYFDAMAKVLAQGRQVLFLLPEINLTPQLLKRVENRFADVPTAVLH
                     SQMAAGRRTQDYLRAMLGQAKLVIGTRLAVFTPMDDVGLIVVDEEHDGSFKQDNELRY
                     HARDLAVWRAKQSGCPVVLGSATPSLESWHKVQSGAYRLLQLTERAHTAAQLPQVDIL
                     NVGRLKLDNGFSPQALQLLKQNFEAGGMSLVYLNRRGFAPALFCGDCGHTFGCPNCSA
                     KMVLHQRVRQLRCHHCDHREPIPFKCPDCGNQDLTAVGHGTQRVEETLRAFLPKAAVV
                     RVDRDSTAHKNDWADLYRRIADNEIDILVGTQMLAKGHDFARLNLVIVLNADGSLYSA
                     DFRAPERLFAELMQVSGRAGRADKPGKVLIQTQLPEHPVFAAVKAQDYAVFAENELNE
                     RQMFAMPPFGFQTAVRADAPRVADAVEFLNAAKETLVPLLPESVSQFGAAPMLMVRLA
                     ERERAQIFLESPSRQDLHRAVSLWVQVLQQNRDGKIRWSVDVDPQEA"
     gene            3506..4288
                     /locus_tag="ACFOAE_000624"
     CDS             3506..4288
                     /locus_tag="ACFOAE_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbC family protein"
                     /protein_id="HFC6884160.1"
                     /translation="MKTKLIKILTPFTVLPLLACGQTPVSNANAEPAAKAESAGKSVA
                     ASLKARLEKTYSAQDLKVLSVSETPVKGIYEVVVSGRQIIYTDAEGGYMFVGELINID
                     TRKNLTEERAADLNKIDFASLPLDKAIKEVRGNGKLKVAVFSDPDCPFCKRLEHEFEK
                     MTDVTVYSFMMPIAGLHPDAARKAQILWCQPDRAKAWTDWMRKGKFPVGGSICDNPVA
                     ETTSLGEQFGFNGTPTLVFPNGRSQSGYSPMPQLEEIIRKNQ"
     gene            complement(4606..6540)
                     /locus_tag="ACFOAE_000625"
     CDS             complement(4606..6540)
                     /locus_tag="ACFOAE_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MacB family efflux pump subunit"
                     /protein_id="HFC6884161.1"
                     /translation="MSLIECKNINRYFGSGENRVHILKDISLSIEKGDFVAIIGQSGS
                     GKSTLMNILGCLDTAGSGSYRIDGIETAKMQPDELAALRRERFGFIFQRYNLLSSLTA
                     RDNVALPAVYMGAGGKERSARADKLLQDLGLASKEGNKPGELSGGQQQRVSIARALMN
                     GGEIIFADEPTGALDTASGKNVMEIIHKLHEAGHTVIMVTHDPGIAANANRVIEIRDG
                     EIISDTSKNPEIPASNVGRIQEKASWSFYYDQFVEAFRMSVQAVLAHKMRSLLTMLGI
                     IIGIASVVSVVALGNGSQKKILEDISSIGTNTISIFPGRGFGDRRSGRIKTLTIDDAK
                     IIAKQSYVASATPMTSSGGTLTYRNTDLTASLYGVGEQYFDVRGLKLETGRLFDENDV
                     KEDAQVVVIDQNVKDKLFADSDPLGKTILFRKRPLTVIGVMKKDENAFGNSDVLMLWS
                     PYTTVMHQITGESHTNSITVKIKDNANTQVAEKGLTDLLKARHGTEDFFMNNSDSIRQ
                     IVESTTGTMKLLISSIALISLVVGGIGVMNIMLVSVTERTKEIGIRMAIGARRGNILQ
                     QFLIEAVLICVIGGLVGVGLSAAVSLVFNHFVTDFPMDISAASVIGAVACSTGIGIAF
                     GFMPANKAAKLNPIDALAQD"
     gene            complement(6606..7784)
                     /locus_tag="ACFOAE_000626"
     CDS             complement(6606..7784)
                     /locus_tag="ACFOAE_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MacA family efflux pump subunit"
                     /protein_id="HFC6884162.1"
                     /translation="MAKMMKWAAVAAVAAAAVWGGWSYLKPEPQAAYITETVRRGDIS
                     RTVSATGEISPSNLVSVGAQASGQIKKLYVKLGQQVKKGDLIAEINSTSQTNTLNTEK
                     SKLETYQAKLVSAQIALGSAEKKYKRQAALWKDDATAKEDLESAQDALAAAKANVAEL
                     KALIRQSKISINTAESELGYTRITATMDGTVVAILVEEGQTVNAAQSTPTIVQLANLD
                     MMLNKMQIAEGDITKVKAGQDISFTILSEPDTPIKAKLDSVDPGLTTMSSGGYNSSTD
                     TASNAVYYYARSFVPNPDGKLATGMTTQNTVEIDGVKNVLIIPSLTVKNRGGKAFVRV
                     LGADGKAAEREIRTGMRDSMNTEVKSGLKEGDKVVISEITAAEQQESGERALGGPPRR
                     "
     gene            8010..8399
                     /locus_tag="ACFOAE_000627"
     CDS             8010..8399
                     /locus_tag="ACFOAE_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
                     /protein_id="HFC6884163.1"
                     /translation="MKNVQKGFTLLELMIAVAILGILTLIAYPSYKTYIRRVRLSEVK
                     STLLMNAQNLERYYRQKGTFDNYDQTKLKQNKYFKITLSKVNPDHFTLQAVPDPTTNE
                     GETCIVTLNDGGTLSAAGNGQSCPDFD"
     gene            8681..9727
                     /gene="adhP"
                     /locus_tag="ACFOAE_000628"
     CDS             8681..9727
                     /gene="adhP"
                     /locus_tag="ACFOAE_000628"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HFC6884164.1"
                     /translation="MKMQAVVVNKNVAGDVEVIEREVRPLEYGEALVEVEYCGVCHTD
                     LHVAAGDYGEKPGRVLGHEGIGLVKEVADGVKNLKVGDRVSIAWLFQSCGSCEYCNTG
                     RETLCRSVLNAGYTADGGMATHCIVSADYAVKVPEGLDPAQASSITCAGVTTYKAIKV
                     SGVRPGQWIAIYGAGGLGNLGVQYAKKVFGAHVVAIDINDDKLAFAKETGADLVVNAA
                     KEDAAKVIQEKTGGAHAAVVTAVSAAAFNSAVNCVRAGGRVVAIGLPPESMDLSIPRL
                     VLDGIEVVGSLVGTRKDLEEAFQFGAEGLVVPKVQLRALDEAPAIFQEMREGKITGRM
                     VIDMKKECGCGHHH"
     gene            complement(9892..13377)
                     /gene="smc"
                     /locus_tag="ACFOAE_000629"
     CDS             complement(9892..13377)
                     /gene="smc"
                     /locus_tag="ACFOAE_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFC6884165.1"
                     /translation="MRLTHIKLSGFKSFTDPTTIHVPGQLVAVIGPNGCGKSNVIDAV
                     RWVLGEASAKQLRGESMQDVIFNGAATRRPAPRASVELVFDNSDHSLQGAWGQYAEVS
                     IKRQLTRQGESTYFINNQTVRRRDITDLFLGTGVGARGYAVIEQGMISRIIEARPEEL
                     RAYIEEAAGVSKYKERRKETEGRLKDTREHLQRLGDLQNELARQVEKLEKQAETAERY
                     KSLTAQLNQQQDLLDYAQWQQSLAAADKATAQHQSLQAQQDETAAQVQALNDEVHALQ
                     TAEQSQQQAVHELSNKRGVLREQIARLEEQIRHRQNLHQRIERDKQAAQAQMQRIHQE
                     QQQIRVQLEENELQAEEKQTELAEWAMQVAEHEERLPELEEAQATLNAAFQTQQDEAN
                     RIRRELALKQQQLAHTGQTIAKHEERKGRLKQENQALNLPYEAETAAAQEAAALLQNR
                     QEHYEEQIIAAEEALHAAREAFQTASNRFQSLKQQHITLQAQQQALSQILSQQQEAAD
                     FWQASDHAAAPQLWQHITAPAEWQHALSVILAERLHARAVPHGFVPPEPLPQGQAAWL
                     SDGLSGGIKKSLPVQALLNQIQAQPPFQTALHHWLDGVLCAPDLSYALAHQSDLGAHQ
                     IWLTPEGHQVDKVSVLLYAKPAQESLIAQKARLDGIASELESLAPELSAAEAAFKQAE
                     AAVRSSEVQHKNLMQQQQQHTRQYSQAQQRAAELLARTNQGQIRREHIERELAQLAEE
                     QTVLQHASDGLSDDIATLQEAAAELEHQQQTTAHSRQEQQGRLKQAQLALLEANRQYG
                     LAEVAVHKLNQQKQNYQQQIARLEQQTLDWQERQQELALAYETEFQNDEQHIKLDELT
                     EAVQTLDEEYIAVQEKLAQIQAQGREQYAKVQTLQTKLPQLQAATQTALLQQQEALIN
                     AKRYHQNLTERAADLDALEALAKESPKVLNTSIGSLSQQIEALGAVNLAALQELEEAR
                     ERDGYYRSQSEDVQAAITLLEEAIAQIDDKTKARFKETFDAVNGKVQTFFPTLFGGGE
                     ATLKMIGDDLLTAGVSIMARPPGKKNSTIHLLSGGEKALTAMSLVFALFSLNPAPFCL
                     LDEVDAPLDDANTSRFCNLVKEMSAQTQFLYISHNRLTMEMAEQLVGVTMQEKGVSRV
                     VAVDIKQALEMAESV"
     gene            13625..14347
                     /gene="lpxH"
                     /locus_tag="ACFOAE_000630"
     CDS             13625..14347
                     /gene="lpxH"
                     /locus_tag="ACFOAE_000630"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HFC6884166.1"
                     /translation="MKPAYFISDLHLSEKHPELTALLLRFLRSSAAGQARAIYILGDL
                     FDFWVGDDEVSELNTSVAREIRKLSDKGVAVFFVRGNRDFLIGQDFCRQAGMTLLPDY
                     SVLDLFGCKTLICHGDTLCTDDKAYQRFRKIVHRKRLQKLFLMLPLKWRTRLAAKIRR
                     VSKMEKQVKPADIMDVNAAFTARQVRAFGAERLIHGHTHREHIHHENGFTRIVLGDWH
                     NDYASILRVDGDGAVFVPLEKY"
     gene            14616..16202
                     /locus_tag="ACFOAE_000631"
     CDS             14616..16202
                     /locus_tag="ACFOAE_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HFC6884167.1"
                     /translation="MALFLSIFPIVLLIWLMVKKNSMPSYVALPITAVLIYAIKLFYF
                     DDAGMLLNATAASGLVKTLTPITVIFGAIMFNRMMETTGCIDVIRKWLATISPNPVAQ
                     LMIIGWAFAFMIEGASGFGTPAAIAAPILMSLGFNPLKVAIFTLVMNSVPVSFGAVGT
                     PTWFGFAPLNLSAEDILAIGRQTGVMHFFAGFVIPVIGLGFIVPWSEIRKNLGFVAIA
                     VFSCTIPYVALAMVNEEFPSLVAGAIGLMVSVFAANQGWGLSKDHAKDPNAEKVPFAQ
                     VAKALAPLGMLIGMLVVTRIKQLGIKGILTSKEEWFSFQLPFDLSKITVSDSLTITFG
                     NIFGQDVSASYQTLYVPAWIPFVLTVWICILLYKTKFKDAWTIYSVTFNQTKKPLLAL
                     MGALIMVQLMLVGGDNSMVKIIGKEFAAMAGEHWVYFSPYLGAIGAFFSGSNTVSNLT
                     FGPIQQQIALDTGLSVTLILALQSVGGAMGNMVCLNNIIAVCTVLDVKNSEGAIIKKT
                     VIPMAIYGVIAVVAAMIFFL"
     gene            complement(16371..16574)
                     /locus_tag="ACFOAE_000632"
     CDS             complement(16371..16574)
                     /locus_tag="ACFOAE_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-finger domain-containing protein"
                     /protein_id="HFC6884168.1"
                     /translation="MDNLNLQEISVLPENLPLYCSGPDNEQWNGHPRVFLPLCEGESG
                     SVACPYCGTRYRLDGKMPHHHYA"
     gene            16690..17187
                     /locus_tag="ACFOAE_000633"
     CDS             16690..17187
                     /locus_tag="ACFOAE_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-mimic protein DMP19"
                     /protein_id="HFC6884169.1"
                     /translation="MTALTLPEDIRQQEPSALLYTLVSAYLEHTAQTGDESLSCLSDD
                     QHTLTAFCYLDSQVEEGGFVQLIASGYGEYIFRNPLADSLRRWKIKAVPKVLDKAKAL
                     YEQHGKTIETLADGGADIESLRKQFPDFEEWDGAYYEAAEQDLPLLAEHIQSNWETFA
                     HIGQA"
     gene            17269..18462
                     /locus_tag="ACFOAE_000634"
     CDS             17269..18462
                     /locus_tag="ACFOAE_000634"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid aminotransferase"
                     /protein_id="HFC6884170.1"
                     /translation="MFFKHIEAAPADPILGLGEAFKAETRPEKVNLGIGVYKDASGAT
                     PLVKAVKEAEKRLLESETTKNYLTIDGVADYNAQTQILLFGKDHEIIASRRAKTAQSL
                     GGTGALRIAAEFAKRQLNAQTIWISNPTWPNHNAIAKAVGIQDKPYRYYDAAKHGLDW
                     DGMIEDLSQAQKGDIVLLHGCCHNPTGIDPTPEQWETLAKLSAEKGWLPLFDFAYQGF
                     GNGLEEDAYGLRVFLKHNTELLIASSYSKNFGMYNERVGAFTLVAEDEETAARAHSQV
                     KTIIRTLYSNPASHGANTIALVLKNDDLKAQWIAELDEMRGRIKAMRQKFVGLLKAKG
                     ASQNFDFIIKQNGMFSFSGLTPEQVDRLKNEFAIYAVRSGRINVAGITDNNIDYLCES
                     IVKVL"
     gene            complement(18866..19801)
                     /gene="hemC"
                     /locus_tag="ACFOAE_000635"
     CDS             complement(18866..19801)
                     /gene="hemC"
                     /locus_tag="ACFOAE_000635"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HFC6884171.1"
                     /translation="MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTR
                     GDQILDKTLSKVGGKGLFVKELEQALYDGRADLAVHSIKDVPMDLPEGFALAAIGERA
                     NPFDAFVSNQYARLEEMPKGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLD
                     NGEYDAIILAAAGLQRLELDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKP
                     LNHDTTHACVTAERALARALGGSCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADA
                     QAPAEYADALGRAVAKKLADDGARELIGAVLNTEN"
     gene            19920..20435
                     /gene="ybeY"
                     /locus_tag="ACFOAE_000636"
     CDS             19920..20435
                     /gene="ybeY"
                     /locus_tag="ACFOAE_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFC6884172.1"
                     /translation="MKRAKQYPFLSLQRQRFHLNFENASSTANLPSERDFYRWAWSAL
                     KNEYRRADISLILLDEEEARAYNRDYRGKDYATNVLSFALNEGEILPCQVSEKLYGDL
                     IICPQVVLKEAAEQGKTPERHFAHLTIHGVLHLMGYDHIEDDEAEIMEAEEIRLMLAA
                     GFPNPYQEDEY"
     gene            20437..21261
                     /locus_tag="ACFOAE_000637"
     CDS             20437..21261
                     /locus_tag="ACFOAE_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HFC6884173.1"
                     /translation="MDGTQSKPKFFERLISRLAGEPDSAEDVLTLLRQAHEQEVFDAD
                     TLLRLEKVLDFSDLEVRDAMITRSRMNVLKENDSIERITAYVIDTAHSRFPVIGEDKD
                     EVLGILHAKDLLKYMFNPEQFHLKSILRPAVFVPEGKSLTALLKEFREQRNHMAIVID
                     EYGGTSGLVTFEDIIEQIVGDIEDEFDEDESADNIHAVSSERWRIHAATEIEDINTFF
                     GTEYSSEEADTIGGLVIQELGHLPVRGEKVIIGSLQFTVARADNRRLHTLMATRVK"
     gene            complement(21404..22783)
                     /gene="nhaC"
                     /locus_tag="ACFOAE_000638"
     CDS             complement(21404..22783)
                     /gene="nhaC"
                     /locus_tag="ACFOAE_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFC6884174.1"
                     /translation="MFAFKSLLDMPRGEALAVVVALIAAMGYTIISLEWLPHMSIIAA
                     IVVLILYGLARGLKYNDMQQGMIGALNQGMGAIYLFFFIGLMVSALMMSGAIPTLMYY
                     GFGLISPTYFYFSAFALCSVIGVSIGSSLTTCATVGVAFMGMAAAFQADMAMTAGAIV
                     SGAFFGDKMSPLSDTTGISASIVGIDLFEHIKNMMYTTIPAWLISAALMLWLLPSVAA
                     QDLNSVESFRSQLEATGLVHCYSLIPFALLVVLALMRINAVVAMLFTVIAAVAVTYLH
                     STPDLRQLGAWFYGGYKLEGEAFKDIAKLISRGGLESMFFTQTIVILGMSLGGLLFAL
                     GAIPSLLDAVRSFLTNAGRATFSVAMTSVGVNFLIGEQYLSILLSGETFKPVYDKLGL
                     HSRNLSRTLEDAGTVINPLVPWSVCGVFISHALGVPVWEYLPYAFFCYLSLALTLLFG
                     WTGLTLSKK"
     gene            complement(23074..24297)
                     /locus_tag="ACFOAE_000639"
     CDS             complement(23074..24297)
                     /locus_tag="ACFOAE_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar MFS transporter"
                     /protein_id="HFC6884175.1"
                     /translation="MSAQSQNNHTSPLVVLTTLFFMMGFITCMNDILIPHLKEIFDLS
                     YVQAMLIQFCFFTAYAVMSIPMGAFVGKVGYKNGVIGGFLLTAVGCLLFYPAAGSHSY
                     AVFLGALFILASGVTLLQVAGNPYVTLLAKPGKESATLTLVQAFNALGTTIAPQIGAF
                     LILADATQTVSKAEQISSVQIPYLGLAGLLIILAVFVKMIRLPDARKIAAEESAHNHD
                     GKTSVWQYKHLVFGTAGIFCYVGAEVSIGSLMVNVLGYLKGLDHASAAHYLSFYWGGA
                     MVGRFLGSAVMAKFAPNRYLAFNASAAVVLLAVAMATGSGNADVAMWSLLAIGFFNSI
                     MFPTIFSLATKGLGKFTNAASGVLCTAIVGGAVVPVVQGWVADTYTLMSSFVVSVICY
                     LYIVFFAVYGYRADK"
BASE COUNT         5648 a         7036 c         6413 g         5634 t
ORIGIN      
        1 aaacggcttg atttgagttt tggtattttt gcccgacggg gtgaaaaata cagttgctat
       61 gcggccgttt ttcgtcggcg cggcggtgct tgccatactc ggcgcgttgg tgtttttcat
      121 cagccccggt gccgtcgtcc tgcaccgcca aatcttctta gaactcatgc tacctgcggc
      181 atatggtggt ttcctgactg cggctttgtt ggactggacg ggtttttcgg gtaacctgaa
      241 acctgtcgcg actttgatgg cggcattatt gctcgccgca tccgctatac tgcccttttc
      301 gccgcaaact gcctcgtttt tcgtcgccgc ctattggctg gtgttgctgc tgttctgcgc
      361 ccggctgatt tggctagacc gaaacaccga caacttcgcc ctgctaatgt tacttgccgc
      421 gttcactgtt tttcagacgg catatgccgt cagcggcgat ttgaacctgt tgcgcgcgca
      481 agtgcatcta aatatggcgg cggtgatgtt cgtatccgtg cgcgtcagta ttcttttggg
      541 cgcggaagcc ctgaaagaat gccgtctgaa agacccagta ttcatcccca atgtcgtcta
      601 taaaaacatc gccattacct tcctgctcct gcacgccgcc gccgaacttt ggctgtctgc
      661 gcaaaccgcc ggttttacct cgctcgccgt cggctttatc ctgcttgcca agctgcgtga
      721 gcttcaccat cacgaactcc tgcgcaaaca ctacgtccgc acttattacc tgctccaact
      781 ctttgccgcc gcaggctatt tgtggacagg cgcggcgaaa ttacaaaacc tgcccgcctc
      841 cgcgcccctg cacctgatta ccctcggtgg catgatgggc agcgtgatga tggtgtggct
      901 gactgccgga ctgtggcaca gcggctttac caagctcgac tacccgaaac tctgccgcat
      961 cgccgtcctc ctgctcttta tggctgccgt ctcgcgtgct ttcttgatga acgtgaatcc
     1021 aatattcttc atcaccgtcc ccgcgattct gaccgccgcc gtgttcgtgc tttacctgct
     1081 gacattcgta ccgatctttc gggcgaacgc gtttacagac gatccggaat aaaaatgccg
     1141 tctgaaacgg tttcagacgg catcgtattg ccgataatca agcctcctgc ggatcgacat
     1201 ccaccgacca tctgattttg ccgtccctgt tttgctgcaa cacctgcacc cacaaactca
     1261 cggcgcggtg caaatcctgt cgggacgggg attcgaggaa gatttgcgcg cgttcgcgtt
     1321 cggcgaggcg caccatcagc atcggggcgg cgccgaactg tgaaacgctt tcgggcaaca
     1381 gcgggaccag ggtttctttg gcggcgttga gaaactccac cgcatcggca acgcgcggcg
     1441 cgtcggcgcg gacggcggtc tggaaaccga agggcggcat ggcgaacatt tgccgctcat
     1501 tcaattcgtt ttcggcaaac acggcataat cctgcgcttt gacggcggcg aagacgggat
     1561 gttcgggcag ttgggtctgt atcaacacct tgccgggttt gtcggcgcgc cccgccctgc
     1621 cggacacctg catcagctcg gcgaacagtc tttccggcgc gcggaaatcc gcgctgtaaa
     1681 ggctgccgtc ggcgttcaat acgataacga ggttgagccg cgcaaagtca tggcctttgg
     1741 cgagcatctg cgtgccgacc agaatgtcga tttcgttgtc ggcgatgcgg cggtacaaat
     1801 ccgcccagtc gtttttgtgc gcggtgctgt ccctgtccac gcggacgacg gctgccttgg
     1861 gcaggaaggc gcgcagggtt tcttcgacgc gctgcgtgcc gtgtccgacg gcggtcaggt
     1921 cttgatttcc gcagtcgggg catttgaacg gtatgggttc gcggtggtcg cagtggtggc
     1981 agcgcagttg gcggacgcgt tggtgcagca ccattttggc ggagcagttc gggcagccga
     2041 aggtatggcc gcagtcgccg caaaacagcg cgggcgcgaa gccgcgacgg ttgaggtaca
     2101 ccagcgacat accgcccgct tcaaaattct gtttcaaaag ctgcaaggct tgcggcgaga
     2161 agccattgtc tagtttcaga cggcctacgt tgaggatgtc cacttgcggc agttgcgcag
     2221 cggtatgggc gcgctcggtc agttgcagca ggcggtacgc gccgctttgc accttgtgcc
     2281 agctctccaa gctgggcgtg gcgctaccca gcacgacggg gcagccgctc tgcttcgccc
     2341 gccacaccgc caaatcgcgg gcgtggtagc gtaattcgtt gtcttgtttg aacgagccgt
     2401 cgtgttcctc atcgaccaca atcagcccga catcatccat cggcgtgaac accgccagcc
     2461 gcgtgccgat gactaatttc gcctgcccca acatcgcgcg caaataatct tgcgtgcgcc
     2521 tgcctgccgc catctggctg tgcaacacgg cggtcggcac gtcggcaaaa cggttttcta
     2581 cccgcttcaa aagctgcggc gtgaggttga tttcgggcaa cagaaacaac acctgccgcc
     2641 cctgagccaa cactttcgcc atcgcatcaa aatacacctc ggtcttgccg ctgccggtga
     2701 tgccgtacag cagaaacggc tggaagcgtc ccaatgccgt ctgaatggca tcggaagcct
     2761 tctgctggtc agcatttaat acaaattcag agtgcgaagc ctgcccatta cacgacctta
     2821 aaacgggctt cgccgcttcc gtcgtttcaa tccaaccctg ttccgcccaa ttttcgatta
     2881 atttcaccgc ctgcgcgttt acctgcttca acgctgccat cgtcatttcg cccgacagca
     2941 gcgcgtccca caaagccgct tttttgttga accgcgccgg cggcggcgtt tgcgccctgc
     3001 ccgcttcgtt cagcgcgtaa aacaacggcg gctgcggcat ttccaccgcg cgcgtttcct
     3061 tcaaaccctg cggcagcgcg gcaaacaccg cctgccccgt cggatagtgg taataacgcg
     3121 acgtaaacga gagcaaatca cgccagcttt caggcaacgg cggcgcgtct aaaaaggtcg
     3181 tctgaatact caaaatccgc gccgtatcca tatccggcgc aatatccgtt tcccacacca
     3241 tcccgaccac ggttttattg cgaaaaggca caagcacccg cattccctgc ggcagcggct
     3301 cggaatggga ataagttaaa agaccgtctg aaagcggcac gtttacggcg atacggtggt
     3361 agatcataca ggcaggcaaa tcattttttt gcgtatttta acaggcggaa gctattttca
     3421 gacgataaat tgagcctagg cgcaatgcag gcgcaacaga gatttgatac aattccgctt
     3481 ttccaacacg cgcaatcatc tttatatgaa aaccaagtta atcaaaatct tgaccccctt
     3541 taccgtcctc ccgctgctgg cttgcgggca aacgcccgtt tccaatgcca acgccgaacc
     3601 cgccgccaaa gccgagtccg ccggcaaatc cgttgccgcc tctttgaaag cgcgtttgga
     3661 aaaaacctat tccgcccaag atttgaaagt gttgagcgtt agcgaaacac cggtcaaagg
     3721 catttacgaa gtcgtcgtca gcggcaggca gattatctac accgatgccg aaggcggcta
     3781 tatgttcgtc ggcgaactca tcaacatcga cacgcgcaaa aacctgaccg aagaacgcgc
     3841 cgccgatttg aacaaaatcg acttcgcctc cctgcctttg gacaaagcca tcaaagaagt
     3901 gcgcggcaac ggcaagctga aagtcgccgt cttctccgac cccgattgtc cgttctgcaa
     3961 acgcttggaa cacgagtttg aaaaaatgac cgacgtgacg gtttacagct ttatgatgcc
     4021 cattgccggc ctgcaccccg atgccgcgcg caaggcgcaa atcttatggt gtcagcccga
     4081 ccgcgccaaa gcgtggacgg attggatgcg taaaggcaaa ttcccggtcg gcggcagcat
     4141 ctgcgacaat cccgtcgcgg aaaccacttc cttgggcgaa caattcggct tcaacggcac
     4201 gccgaccctc gtcttcccca acgggcgcag ccaaagcggc tacagcccga tgccccaact
     4261 ggaggaaatc atccgcaaaa atcaataatc catccgcaaa acaaaaggct tggaaaattc
     4321 caagcctttt ttgcgggaaa tgccgcctga aaaccaatcc gcactgaaag ttatagtgga
     4381 ttaaatttat agtggattaa atttaaacca gtacagaaag ccaacaaaca catcctaacc
     4441 cattgaatga ttgaaaataa taaattgaac aatacgaaac acaccgccgt cattcccacg
     4501 caagtgggaa tctggaacgt agaatctaag aaaccgtttt gtccgataag tttctgctcc
     4561 aaaatgaccg gtccggcagc ttcaaacggc atctttgtgc caacctcaat cctgcgccaa
     4621 tgcgtctatc ggattgagtt tggctgcttt attggcaggc ataaagccga acgcgatgcc
     4681 gattccggtc gagcaggcga ccgccccgat aacggatgcc gccgaaatgt ccatcgggaa
     4741 gtcggttaca aaatgattga acacgaggct gacggcggcg gacaaaccca cgccgaccaa
     4801 accgccgatg acgcagatta acaccgcctc aatcaaaaac tgctgcaaaa tattgccgcg
     4861 ccgcgcgccg attgccatcc gtatgccgat ttctttggtg cgctcggtaa cggacaccag
     4921 catgatgttc atcacgccga tgccgccgac taccaatgaa atcagggcga tggaggaaat
     4981 cagcagcttc atcgtaccgg tggtgctttc gactatctgc ctgatgctgt cgctgttgtt
     5041 catgaagaaa tcttccgtgc cgtgccgcgc tttgagcaga tcggtcagcc ctttttcggc
     5101 aacctgggta ttggcattgt ctttgatttt gacggtgatg gagttggtgt ggctctcgcc
     5161 tgtgatttgg tgcatcaccg tcgtataggg cgaccaaagc atcagcacgt cggaattgcc
     5221 gaaagcgttt tcgtcttttt tcatcacgcc gatgacggtc aaggggcgtt tcctgaacaa
     5281 aatggtttta cccaacggat ccgagtccgc aaagagtttg tctttgacat tttggtcgat
     5341 gacgacgacc tgcgcgtctt ctttcacatc gttttcgtca aacagccgcc ccgtttccag
     5401 cttcagtccg cgcacgtcga aatattgttc gcccacgccg tacaaagaag cggtcaggtc
     5461 ggtattgcgg taagtcagcg tgccgccgct cgaagtcatg ggcgtggcgg aagcaacgta
     5521 gctttgtttg gcgatgattt ttgcgtcgtc tatggtcagg gttttaatcc tgccgctgcg
     5581 cctgtcgccg aagccgcgcc ccgggaagat gctgatggtg ttcgtcccta tcgaactgat
     5641 gtcttcaagg atttttttct gcgaaccgtt gcccaatgcg acgacggaaa ccaccgacgc
     5701 gatgccgatg atgatgccga gcatcgtcag aagcgaacgc attttgtgcg ccaatactgc
     5761 ttgcaccgac attctgaagg cttcgacaaa ctggtcgtaa taaaacgacc acgaggcttt
     5821 ttcctgaatc ctcccgacat tgcttgcggg gatttcggga tttttcgagg tgtcggaaat
     5881 gatttcgccg tcccggattt cgatgacgcg gttggcgttg gcggcaatgc cggggtcgtg
     5941 cgtgaccata atgacggtat gcccggcttc gtgcagctta tggatgattt ccatcacgtt
     6001 tttgccgctg gcggtatcga gcgcgccggt cggctcgtcg gcgaagatga tttctccgcc
     6061 gttcatcagg gcgcgggcga tggagacgcg ctgctgctgt ccgcccgaga gttcgccggg
     6121 cttgttgccc tctttgcttg ccaaacccaa atcctgcaag agtttgtccg cccgcgcgga
     6181 acgctctttg ccgcccgcgc ccatatagac ggctggcagc gcgacgttgt cccttgcggt
     6241 cagcgagctt aagaggttgt agcgttggaa gatgaaaccg aagcgttcgc ggcgcaatgc
     6301 cgccagctcg tcaggctgca ttttggcagt ttcgatgccg tcgattcggt acgaaccgga
     6361 accggcggta tccaaacagc cgagtatgtt catcagcgtg gacttgcccg aaccggactg
     6421 cccgatgatg gcgacaaaat cgcccttctc tatcgacagg ctgatgtctt tcaaaatatg
     6481 gacgcggttc tcgccgctgc cgaaatagcg gttgatgttt ttacattcga tcaagctcat
     6541 aatattccgt aaatcaataa caaatgccgt ctgaaaccgt ttccgtgttc agacggcata
     6601 ttcgtttatc ggcgcggcgg gccgcctagg gcgcgttcgc cgctttcctg ctgctcggcg
     6661 gcggttattt cggagatgac cactttgtcc ccctctttca acccgctttt tacttcggta
     6721 ttcatactgt ctctcatacc ggtccggatt tcgcgttccg ccgccttgcc gtccgcaccc
     6781 aacacgcgca caaacgcctt gccgccgcga tttttcacgg tcagcgacgg aataatcagc
     6841 acatttttca cgccgtcgat ttcaaccgta ttctgcgtcg tcatccccgt ggcgagtttg
     6901 ccgtccggat tcggcacaaa cgaacgggca taatagtaga ccgcattgga agccgtatcc
     6961 gtactgctgt tgtaaccgcc cgacgacatc gtggtcagcc cggggtcgac gctgtcgagc
     7021 ttcgccttaa tcggcgtatc cggttcggac aaaatcgtaa acgaaatatc ctgccccgcc
     7081 ttcaccttgg taatatcgcc ctcggcaatc tgcattttgt tcaacatcat atccagattc
     7141 gccaattgga caatcgtcgg cgtagactgc gccgcgttca cagtctgccc ctcttccacg
     7201 agaatcgcca ccaccgtgcc gtccatcgtt gcggtaatgc gcgtgtagcc caattccgac
     7261 tcggcggtat tgatggaaat tttgctctgt ctgattagag ccttcagctc ggcaacattg
     7321 gctttggcgg cggcaagcgc atcctgtgcg ctttccaaat cttctttagc ggtcgcatca
     7381 tccttccaca acgccgcctg acgcttatat ttcttctccg cgctgcccaa tgcaatctgt
     7441 gccgacacca gcttcgcctg atacgtttcc aacttggatt tttccgtatt gagcgtattg
     7501 gtctgcgagg tcgaattgat ttccgcaatc aaatcgccct ttttaacctg ttgcccgagt
     7561 ttgacataaa gtttcttaat ctgccccgat gcctgcgcgc cgaccgatac caggttggac
     7621 ggcgaaatct cccctgttgc agaaaccgtc cggctgatgt cgccgcgcct gaccgtttcc
     7681 gtaatataag cagcctgcgg ctcgggcttc agataagacc atccgcccca aaccgctgcc
     7741 gccgcgaccg ccgcaacagc cgcccatttc atcatttttg ccatgttttc aattctctgt
     7801 atgcgtcaat cccataaatc ggaagcggat tctaccgcaa gtccctgccc catccaaggc
     7861 ggcaaactgc cgacaataaa aataaccatt tgttttaaat ggcttataca atctgctttc
     7921 ccgaaaattt caatccgttt acatattccg ccatttccga tacggcgtta taatgccgtc
     7981 gaccgacaaa caaatggaaa cacattgcta tgaaaaacgt tcaaaaaggc tttacgctgc
     8041 tcgagctgat gattgccgtc gccatcctcg gcatcctgac gctcatcgcc tacccttcct
     8101 ataaaaccta catccggcgc gtccgcctgt cggaagtcaa atccaccctg ctgatgaacg
     8161 cgcaaaactt agagcgttac taccgccaaa aagggacgtt tgacaactac gaccaaacca
     8221 aactgaaaca aaacaagtat ttcaaaatta ccttaagcaa agtcaacccc gaccacttca
     8281 cccttcaggc cgtccccgat ccgacgacca acgaaggcga aacctgcatc gtcacgctca
     8341 acgacggcgg cacactgtcc gccgccggca acgggcagtc ctgcccggac ttcgactaat
     8401 cctccgccga agcccgcaaa cccgtaaaga tgccgtccgg acacagcttc agacggtatc
     8461 tttacgggtt tgcccatccg gtttttcaaa cttgaaacct gccgcccctc atccggcaac
     8521 cgccccgatg ctgtgcctcc ccaactgtta taatataaca tataacccat atttttcaac
     8581 aacataccac ttgacctgtg agatgcggaa gcgtatgctt acccttatat cggacaacat
     8641 tccgtttaca ggttttttgc cgtaactaag gagcgcaatc atgaaaatgc aggcagttgt
     8701 tgtgaataaa aatgtagcgg gcgatgtgga agtaatcgaa cgcgaggttc gcccgttgga
     8761 atacggcgag gcgttggtcg aagtcgaata ttgcggcgtg tgccacaccg acctgcacgt
     8821 tgcggcaggc gactacggcg aaaaaccggg ccgcgtgctg ggacacgagg gcatcggttt
     8881 ggttaaagaa gttgccgacg gtgtgaaaaa tctgaaagtc ggcgaccgcg tcagcatcgc
     8941 ctggctgttc caaagctgcg gctcgtgcga atactgcaat accggccgcg aaaccctgtg
     9001 ccgttccgta ttgaacgcgg gctacaccgc cgacggcggt atggcgaccc actgcatcgt
     9061 gagtgccgat tacgcggtca aagtcccaga aggtttggat cctgcgcaag cttccagcat
     9121 tacttgtgcc ggtgtaacca cttataaagc cattaaagtt tccggcgttc gtccgggaca
     9181 gtggattgcg atttacggcg cgggcggttt gggcaacttg ggggttcaat acgcgaaaaa
     9241 agtattcggc gcgcacgttg tcgccatcga catcaacgac gacaaactgg cgtttgccaa
     9301 agaaaccggc gcggatttgg ttgtcaacgc cgccaaagaa gacgctgcca aagtgattca
     9361 ggaaaaaaca ggcggcgcac acgctgcggt cgtaaccgcc gtatctgctg ccgcattcaa
     9421 ctctgccgtg aattgcgtcc gcgcgggcgg acgtgtggtt gccatcgggc tgccgccgga
     9481 atcgatggat ttgtccatcc cgcgtttggt tttggacggc atcgaagtgg tcggctcttt
     9541 ggtcggcacg cgcaaagatt tggaagaagc cttccaattc ggcgcggaag gtttggttgt
     9601 gccgaaagtc caactgcgtg ctttggatga agcacccgcc attttccaag aaatgcgcga
     9661 aggcaaaatc accggccgta tggtgatcga tatgaaaaaa gaatgcggct gcggtcatca
     9721 ccactgattt gacgtggcga tacacatcga aatgccgtct gaacgctgtt cagacggcat
     9781 tttttatgga tttggatttg attttaatct gttctgtttg aaataccgtc tgaaaacccg
     9841 tatcgcaaca cgtcattaag aacggcaaga ttcaaccgtt ctgcaacccg tttagacgga
     9901 ttccgccatt tccaacgcct gtttgatgtc cacggcgacg acgcgcgata cgcctttttc
     9961 ctgcatggtt acgcctacga gctgctctgc catttccatg gtcaggcggt tgtgggagat
    10021 gtagaggaac tgggtttgcg ccgacatttc tttgaccagg ttgcagaaac gcgaggtgtt
    10081 ggcgtcgtcc agcggggcat cgacttcgtc caaaaggcag aagggggcgg ggttgaggct
    10141 gaacagggcg aacacgaggc tcatggcggt gagggctttt tcgccgccgg agaggaggtg
    10201 gatggtgctg tttttcttgc cgggcggacg cgccatgatg gatacgccgg cggtcaggag
    10261 gtcgtcgcct atcattttga gggtggcttc gccgccgccg aacagggttg ggaagaaggt
    10321 ttggactttg ccgttgacgg catcgaaggt ttctttgaaa cgcgctttgg ttttatcgtc
    10381 gatttgggcg atggcttctt ccaaaagggt gatggcggcc tgcacgtctt cgctttggct
    10441 gcggtagtag ccgtcgcgtt cgcgcgcttc ttcgagttct tgcagggcgg cgaggttgac
    10501 cgcgccgagg gcttcgattt gttgcgaaag gctgccgatg ctggtgttca atactttcgg
    10561 cgattctttc gccaacgctt cgagcgcgtc caaatcggcg gcgcgttcgg tcaggttttg
    10621 atggtagcgt ttggcgttga tcagggcttc ctgctgctgc aacagggcgg tttgggtagc
    10681 ggcctgaagc tgcggcagct tggtttgcag ggtttgcact ttagcgtatt gctccctgcc
    10741 ctgcgcctga atctgcgcga gtttttcctg tacggcgatg tactcttcat ccaaagtttg
    10801 tacggcttcg gtcaactcgt cgagttttat gtgctgctcg tcgttttgga actcggtttc
    10861 ataggcgagg gcaagctctt gctggcgttc ctgccaatcg agggtttgct gttcgagtcg
    10921 ggcgatttgc tgttggtagt tttgtttttg ctggttgagc ttgtggacgg cgacttcggc
    10981 aagcccgtat tggcggttgg cttccagcag ggcaagctgc gcctgtttca gacgaccttg
    11041 ctgctcttgg cggctgtgtg cggtggtttg ctgctggtgt tcgagttcgg cggcggcttc
    11101 ctgcaaagta gcaatgtcgt ctgaaagccc gtcggacgcg tgttgcaaca cggtctgctc
    11161 ttccgccaac tgcgccagtt cgcgctcgat gtgttcgcgg cggatttgcc cttggttggt
    11221 acgcgccaga agttcggcgg cgcgttgctg cgcttggctg tattggcgcg tgtgctgctg
    11281 ttgctgctgc atcaggtttt tatgctgcac ttcggacgag cgcacggcgg cttccgcctg
    11341 tttgaacgcg gcttcggcgg cagaaagttc gggggcgagg ctttccagtt cggaagcgat
    11401 gccgtcgagg cgcgcttttt gggcaatcaa gctttcctgc gcgggcttgg catagagcag
    11461 aacgctgact ttatcgacct gatggccttc gggtgtgagc cagatttggt gtgcgcccaa
    11521 atcgctttga tgcgcgaggg catagctcaa atcgggcgcg cacaatacgc cgtcgagcca
    11581 gtggtgcaat gccgtctgaa acggcggctg cgcttggatt tggttcagca atgcctgtac
    11641 gggcagggat tttttgatgc cgccggagag gccgtctgaa agccatgccg cctgcccctg
    11701 cggcaaaggt tcgggcggta cgaagccgtg cggcacggcg cgggcgtgca ggcgttcggc
    11761 aaggatgacg gacaaggcgt gctgccactc ggcgggcgcg gtgatgtgtt gccacagttg
    11821 cggcgcggcg gcgtggtcgc ttgcctgcca gaagtcggcg gcttcctgct gttgcgacag
    11881 gatttgcgac aacgcctgct gctgcgcctg caaggtgatg tgttgctgct tcaggctttg
    11941 gaagcggttt gatgccgtct gaaacgcctc gcgggcggcg tgtagagctt cttcggcggc
    12001 gatgatttgt tcttcgtaat gctcttgccg gttttgcaac aaggcggcgg cttcctgcgc
    12061 ggcggcggtt tcggcttcgt agggcaggtt cagggcttgg ttttcctgtt tcagacggcc
    12121 tttgcgctct tcgtgtttgg caatcgtttg tccggtatgg gcaagctgct gctgcttcaa
    12181 cgccagttcg cggcggatgc ggttcgcctc gtcctgctgg gtttggaagg cagcattgag
    12241 cgtggcttgg gcttcttcca attcgggcag acgctcttcg tgttcggcaa cctgcatcgc
    12301 ccattccgcc aattcggttt gcttctcttc ggcctgcaat tcgttttctt caagctgcac
    12361 gcggatttgc tgctgctcct gatggatgcg ctgcatctgc gcctgcgccg cctgtttatc
    12421 gcgttcgatg cgttggtgca ggttttgccg gtggcggatt tgttcttcca aacgggcaat
    12481 ctgctcgcgc aacacgccgc gtttgttgct caattcgtgt accgcctgct gctgcgactg
    12541 ttcggcggtc tgcaaggcgt gtacttcgtc gtttaacgcc tgaacctgcg cggcggtttc
    12601 gtcctgctgc gcctgcaaag attgatgctg cgcggtcgcc ttgtcggcgg cggcaagcga
    12661 ttgctgccat tgggcgtaat cgagcaaatc ctgctgttgg ttcaactgcg cggtcaggga
    12721 tttgtagcgt tcggcggttt ccgcttgttt ttccagcttt tccacctgac gcgccaactc
    12781 gttctgcaaa tcgcccaaac gctgcaaatg ctcgcgcgtg tctttcagac ggccttccgt
    12841 ctccttgcgg cgttccttat atttggacac acctgccgcc tcctcgatat aggcacgcaa
    12901 ctcctccggc cgcgcttcga tgatgcgcga aatcatcccc tgctcgataa cggcataacc
    12961 gcgcgcaccc acgcccgtac ctaaaaacaa atcggtaatg tcgcggcggc gcacggtctg
    13021 attgttgatg aaataagtcg attcgccctg acgcgtcaac tgccgcttga tgctcacctc
    13081 ggcatactgc ccccacgccc cctgcaaact gtggtcgctg ttgtcaaaca ccagctccac
    13141 cgaagccctc ggcgcaggac ggcgcgtcgc cgcaccgtta aaaatcacgt cctgcatact
    13201 ctcgccgcga agctgcttcg ccgaagcctc acccaacacc cagcgcaccg cgtcaatcac
    13261 attcgacttg ccgcagccgt tgggcccgat aaccgcgaca agctgccccg gcacatgaat
    13321 tgtggtcggg tcggtaaaag atttgaagcc ggagagtttg atatgggtca ggcgcataat
    13381 ggtcggaaaa aataaaaaag aagcgtattt taacggaaat cccgccgcac caccccatat
    13441 cttgccggca aaaccttacc gcatcccgca ccctcgatgc cgtctgaagc cttcagacgg
    13501 cattttaacg cgcccgaacc ccggttccgc caatgcccga tgcttggcgc ggcatttgcc
    13561 gtattgcccc gccgccgggc gcgttataat ccgccacgac atccgcccga ttggaaacct
    13621 gcctatgaaa cccgcctatt tcatctccga cctgcatttg agcgaaaagc accccgaact
    13681 gaccgcgctg ctgctgcgtt ttttacgttc ttccgccgcc gggcaggcgc gggcgattta
    13741 tattttgggc gatttgtttg atttttgggt gggcgatgac gaagtttccg agttgaatac
    13801 ttcggttgcg cgggaaatca ggaaattgtc cgacaaaggc gttgccgtgt tcttcgtcag
    13861 gggcaaccgc gacttcctga tcggtcagga tttttgccgg caggcgggta tgacgctgct
    13921 gccggattac tcggttttgg acttgttcgg ctgcaaaacc ctcatctgcc acggagacac
    13981 attatgcacc gacgacaagg cataccaacg tttccgcaaa atcgtgcatc ggaagcggct
    14041 gcaaaaactg ttcctgatgc tgcccctgaa gtggcgcacg cgccttgccg ccaaaatcag
    14101 gcgtgtcagc aaaatggaaa aacaggtcaa gcccgccgat attatggatg tcaatgccgc
    14161 ctttaccgcg cggcaggtac gcgccttcgg tgcggaaagg ctgatacacg gacacaccca
    14221 ccgcgagcat atccatcacg aaaacggctt tacccgcatc gttttgggcg actggcataa
    14281 cgactatgct tcaatcctcc gcgtggacgg ggacggcgcg gtattcgtgc cgctggaaaa
    14341 atactgaaaa tgccgtctga agcctttcgg gcggcttttt ttacacgccc ctttcccaca
    14401 ctccctccgc cgcatcatca ccatccttaa cccgcattaa tagccattat cgataaaatg
    14461 cttgaccgat tacataagat tacgtaaagt gtgcaaacgc ataacaattg gtcttaccaa
    14521 tttatctttt aaccaaaata tcgggtgtac gggatttgaa cgtctttcca aacctcgacg
    14581 cgccttatga tgcaaatgcc taaaaaggat tcgttatggc acttttcctc agcatattcc
    14641 ccatcgtcct gctgatttgg ctgatggtga aaaaaaacag tatgccctcc tacgtcgcgc
    14701 tgccgattac cgcagtgctg atttacgcca tcaaactttt ctacttcgac gatgcgggca
    14761 tgctgctcaa cgccaccgcc gcttccggcc tcgtcaaaac gctcacgccg attaccgtga
    14821 ttttcggcgc gattatgttc aaccgtatga tggaaaccac gggctgcatc gatgtcatcc
    14881 gcaaatggct ggcgaccatc agcccgaacc ccgtagcgca actgatgatt atcggctggg
    14941 cttttgcctt tatgattgaa ggcgcatccg gcttcggcac gcctgccgcg attgccgcgc
    15001 cgattctgat gagcttgggc ttcaacccgt tgaaagtggc gattttcact ttggtgatga
    15061 actccgtccc cgtctctttc ggcgcggtcg gtacgccgac ctggttcggt ttcgcaccgc
    15121 tgaacctgag tgccgaagac atcctcgcca tcggcaggca gaccggcgta atgcacttct
    15181 tcgcaggttt cgtcatcccc gtcatcggct tgggcttcat cgtaccttgg tctgaaatcc
    15241 gcaaaaactt gggcttcgtc gccattgccg tcttctcctg caccattcct tatgtcgcat
    15301 tggcgatggt caacgaagaa ttcccgtcgc tcgtcgccgg cgcgatcggc ctgatggtgt
    15361 ccgtattcgc cgccaaccaa ggctggggct tgagcaaaga ccacgccaaa gacccgaatg
    15421 ccgaaaaagt gccgttcgcc caagtcgcca aagcactcgc ccctttgggt atgctgatcg
    15481 gcatgctggt ggttacgcgc atcaaacagc tcggcatcaa aggcattttg accagcaaag
    15541 aagaatggtt cagcttccaa ctgccgtttg atttgtccaa aatcaccgtc agcgactccc
    15601 tgacgattac cttcggcaat attttcggac aagatgtcag cgcgtcttac caaacgctgt
    15661 acgtcccggc ttggattccg tttgtgctga ccgtttggat ttgcatcctg ctgtataaaa
    15721 ccaaattcaa agatgcctgg acgatttatt ccgtaacttt caatcaaacc aaaaaaccgc
    15781 tgcttgccct gatgggcgcg ctgattatgg ttcagctgat gctggtcggc ggcgacaatt
    15841 cgatggtgaa aatcatcggt aaggaatttg ccgcaatggc gggcgaacac tgggtttatt
    15901 tctcgccgta tctgggcgcg atcggtgcgt tcttctccgg ctccaacacc gtgtccaacc
    15961 tgactttcgg accgattcag cagcaaatcg ccttggatac cggcctgtcc gttaccctga
    16021 ttctggcgtt gcagtccgtc ggcggcgcga tgggcaatat ggtgtgcctc aacaacatca
    16081 tcgccgtatg taccgtattg gacgtgaaaa attccgaagg tgcgattatc aagaaaaccg
    16141 ttatcccgat ggcgatttac ggcgtgattg ccgtcgtcgc ggcaatgatt ttcttcctct
    16201 aggcgaaacg ccaccatcca tagcggcagc acgcggggaa cggaaaccgc cgttccccgt
    16261 ccgggcggcg cgtcgggcag aatcccggtg ccggaacaag cccgccccgc caaacaaatg
    16321 ccgtctgaaa ccggaaaagg cttcagacgg catttttccg ccgcttgcgt tcaggcgtaa
    16381 tgatgatgcg gcatcttgcc gtcaaggcgg tagcgcgtgc cgcaatacgg gcaggcaacg
    16441 ctgcccgatt ctccttcgca caaaggcaaa aacactctcg gatgcccgtt ccactgctcg
    16501 ttgtcgggtc ccgagcaata cagcggcaga ttttccggca acacggaaat ttcctgcaga
    16561 ttcagattgt ccatttgatt ttcctttgcg tggttggcgt gcgcccattt tacgccatcg
    16621 gcaggctaaa ggatattttc ggcgcaaagc cgcaatccgc tataatcccc acttttcaga
    16681 cggcatacca tgactgcgct tacccttccg gaagacatcc gccaacaaga gccatccgcc
    16741 ctgctctata ccctcgtttc cgcctacctc gaacacaccg cccaaaccgg cgacgaatcc
    16801 ctctcctgcc tgtccgacga ccagcacacg ctgaccgcat tctgctacct cgacagccaa
    16861 gtcgaagaag gcggcttcgt gcaactcatc gcctccggtt acggcgaata tattttccgc
    16921 aacccgcttg ccgacagcct gcgccgctgg aaaatcaaag ccgtgccgaa agtcttggac
    16981 aaagccaaag ccctctacga acaacacggc aaaaccatcg aaacgctcgc cgacggaggc
    17041 gcagacatcg aatccctgcg caaacagttc cccgactttg aagaatggga cggcgcatac
    17101 tacgaagccg ccgaacaaga cctgcccctg cttgcagaac acatacagtc aaactgggaa
    17161 accttcgccc atatcgggca ggcgtgattg cgtctgtttc cagcccgtgt aaaacagcgt
    17221 aaaatcggca aacccgaatg accttccgtc cccatcaagg agcaagctat gttcttcaag
    17281 cacatcgaag ccgcccccgc cgatccgatt ctcggtttgg gcgaagcgtt caaagccgaa
    17341 acccgccccg aaaaagtcaa cctcggcatc ggcgtttata aagacgcatc cggcgcgaca
    17401 cccctcgtca aagccgtcaa agaagccgaa aaacgcctgt tggaaagcga aacaaccaaa
    17461 aactacctca ccatcgacgg tgttgccgac tacaacgcgc aaacccaaat cctgctgttc
    17521 ggcaaagacc acgaaatcat cgccagccgt cgcgccaaaa cagcgcaaag cctcggcggt
    17581 acgggcgcat tgcgtattgc ggccgagttt gccaaacgcc agttgaacgc gcaaaccatc
    17641 tggatttcca atccgacttg gcccaaccac aacgccatcg ccaaagcggt cggtatccaa
    17701 gacaaacctt atcgttacta tgatgccgcc aaacacggtt tggattggga cggcatgatt
    17761 gaggacttga gccaagcgca aaaaggcgac atcgtcctgc tgcacggctg ctgccacaat
    17821 cctaccggca tcgaccctac gcccgaacaa tgggaaactt tggcaaaact ttctgccgaa
    17881 aaaggctggt tgccgctgtt tgactttgcc taccaaggct tcggcaatgg tttggaagaa
    17941 gatgcctacg gcttgcgcgt gttcttgaaa cacaatacag aattgctgat tgccagctct
    18001 tattccaaaa acttcggtat gtacaacgag cgcgtcggcg cgttcacttt ggtggccgaa
    18061 gatgaagaaa cagcagcccg cgcccacagc caagtcaaaa ccatcatccg taccttgtat
    18121 tccaacccgg cttcacacgg tgcgaacacc attgcgctgg tgttgaaaaa tgatgatttg
    18181 aaagcacaat ggattgccga actcgatgaa atgcgcggcc gcatcaaagc catgcgccaa
    18241 aaatttgtcg ggttgctcaa agccaaaggt gcaagccaaa actttgattt cattatcaaa
    18301 caaaacggta tgttctcttt cagcggcttg actcccgaac aagtcgaccg cctgaaaaac
    18361 gagtttgcca tttatgccgt ccgctccggc cgcatcaacg tcgccggcat taccgacaac
    18421 aacatcgatt atctgtgcga aagcatcgtg aaagtactgt aaaaagcaca gccatatgaa
    18481 aatgccgtcc gaaccttaac cagttcagac ggcatctgtt ttttgttaaa aaacaataaa
    18541 ccataacaat ttcaaacaag ctaaaaacat ctataaaatc aacccaatat gatgaactca
    18601 aataaaaaat acgaatatca tcattctcaa attcaaaatt tgaacgccac agtattatcc
    18661 gaagccacaa aaacctttcc gccgtcattc ccgcgcaggc gggaatccgg gaatccaatg
    18721 ctgcaagaat tgattaaaaa caactgaaac cgagcaaact ggattcccgc ctgcgcggga
    18781 atgacgaaat aaggcgagta aaactgatga aacaaattga ttaaaaacaa taacttatat
    18841 tattttattt aaattttcga taaaatcaat tttccgtatt caatactgct ccaatcaatt
    18901 cccgcgcacc gtcgtccgcc aatttcttag cgacagcgcg tccgagcgcg tcggcatatt
    18961 cggcaggggc ttgcgcgtcc gcccgcaaca caaccgaacc gtcgggatga ccgaccaagc
    19021 cgcgcaaggt cagcaagccg ttttcttccg tgcaatatgc ggccaaaggc acttggcagc
    19081 ttccgcccaa agcgcgcgcc aaagcgcgtt cggccgtaac gcaggcgtgt gtggtatcgt
    19141 ggtttagcgg ttttaaaacc tcatacaaat cttcgcggtg cgcggcaatt tcgataccca
    19201 atgcgccttg tccggcggca ggcaggctgt cggattccga caaaatcatg cggatgcgtc
    19261 cgtccaattc cagacgctgc aaaccggcgg cagccaagat aattgcgtcg tattcgccgt
    19321 tatcgagttt ggacaaacgg gtttgcacat tgccgcgcaa aggtttgata agcaaatgcg
    19381 gatagcgcgc acgcaactgg gcttcgcggc gcaggctgga tgtgcctacg acggcgcctt
    19441 tgggcatttc ttccaaacgc gcgtattggt tggacacaaa cgcgtcaaac ggattggcgc
    19501 gttcgccgat ggctgcaagc gcgaaacctt caggcaaatc catcggcaca tctttaatcg
    19561 aatgcacggc caagtcagcg cgcccgtcat ataaagcctg ttccaactct ttgacaaaca
    19621 agcccttacc gccgactttt gacaaagttt tgtccaaaat ctggtcgccg cgcgtggtca
    19681 tgcccaaaat ctcgacttcg caatcgggat acagggcttt cagacggcct tggatatgct
    19741 ttgcctgcca catggcaagc aggctttcgc gactggcgat aacgagtttt ttcgggttca
    19801 taatggttgc ctgaaagatg gaaaacggca tgaagtctat catattttgg gcggtctttc
    19861 agacggcatg agggtgaata tgttatattt acgcctaaaa accaaatttt ccggacaaca
    19921 tgaaacgcgc caaacaatat ccttttttat ccttacagcg acaacgtttt catctgaact
    19981 ttgaaaacgc ttcttccacc gccaaccttc cgagcgaacg cgatttctac cgctgggcgt
    20041 ggtctgcctt gaaaaatgaa taccgccgcg ccgacatcag cctgattctt ctggacgaag
    20101 aagaagcccg agcctacaac cgcgactacc gcggcaaaga ttacgccacc aatgtattga
    20161 gtttcgcgct caacgaaggc gaaatcctgc cctgccaagt ttcggaaaaa ctgtacggcg
    20221 atttgattat ctgcccgcaa gtggttttga aagaagccgc cgaacagggc aaaacgcccg
    20281 aacggcattt tgcccacctg accatacacg gcgttttgca cctgatgggc tacgaccaca
    20341 tcgaagacga tgaagccgaa ataatggaag ccgaagaaat ccgcctgatg ctggcggcag
    20401 gcttccccaa cccctaccaa gaggacgaat attaaaatgg acggtacgca gtcgaaaccc
    20461 aagtttttcg aacgcctgat ctcccgactt gccggcgagc ccgactccgc cgaagacgta
    20521 ttgaccctgc tgcgccaagc gcacgagcag gaagtttttg atgcggatac gcttttaagg
    20581 ttggaaaaag tcctcgattt ttccgatttg gaagtgcgcg atgccatgat tacgcgcagc
    20641 cgtatgaacg ttttaaaaga aaacgacagc atcgaacgca tcaccgccta cgttatcgat
    20701 accgcccatt cgcgcttccc cgtcatcggt gaagacaaag acgaagtttt gggtattttg
    20761 cacgccaaag acctgctcaa atatatgttc aaccccgagc agttccacct caaatcgata
    20821 ttgcgccctg ccgtcttcgt ccccgaaggc aaatcgctga ccgccctttt aaaagagttc
    20881 cgcgaacagc gcaaccatat ggcgatcgtc atcgacgaat acggcggcac gtcgggtttg
    20941 gtaacttttg aagacatcat cgagcaaatc gtcggcgaca tcgaagatga gtttgacgaa
    21001 gacgaaagcg cggacaacat ccacgccgtt tcttccgaac gctggcgcat ccacgcggct
    21061 accgaaatcg aagacatcaa caccttcttc ggtacggaat acagcagcga agaagccgac
    21121 accattggcg gcctggtcat tcaagagttg ggacatctgc ccgtgcgcgg cgaaaaagtc
    21181 attatcggca gcctgcaatt taccgtcgca cgcgccgaca accgccgcct gcatacgctg
    21241 atggcgaccc gcgtgaagta agcagagcct gcccgcaccg ccgtttctgc acagtttagg
    21301 atgacggtac ggacgttttc tgtttcaatc cgccccatcc gccaaacata aaaatgccgt
    21361 ctgaaaccgg aaaacaggtt cagacggcat ttcgcttatc cgcttatttt ttgctcaaag
    21421 tcagccccgt ccagccgaat aacagggtta aagccaaact caaatagcag aaaaaggcat
    21481 agggcagata ttcccagacc ggcacaccca gcgcatggct gataaatacg ccgcacacgc
    21541 tccacggaac aagcgggttg atgaccgtac ccgcgtcttc gagcgtacgc gagaggttgc
    21601 gggaatgtag tccgagctta tcgtaaacgg gtttgaacgt ttcacccgac aacaaaatac
    21661 tcaaatattg ctcgccgatc aggaaattaa ccccgaccga agtcatggca acgctgaatg
    21721 tggcacgtcc ggcattcgtc aaaaagctgc ggacggcatc cagcagggaa ggaatcgcgc
    21781 ccagcgcaaa cagcagcccg cccaaactca tcccgagaat cacgatggtt tgcgtgaaaa
    21841 acatactttc caagccgccg cgcgaaatga gtttggcgat gtctttaaac gcttcgcctt
    21901 cgagtttgta gccgccgtaa aaccacgcgc cgagctgacg cagatcgggc gtgctgtgca
    21961 gatacgttac ggcaacggcg gcaatgacgg taaagagcat agcgacgacg gcgttgatgc
    22021 gcatcaatgc caaaacgacc aacagcgcaa acggaatcag cgaatagcag tgcaccaatc
    22081 ccgtggcttc aagctggctg cggaaggatt cgacgctgtt caaatcctgc gcggcgacgc
    22141 tgggaagaag ccacagcatc agtgccgcac tgatgagcca cgcgggaatg gtggtgtaca
    22201 tcatattttt gatgtgttca aacaggtcga taccgacaat ggacgcggaa atgcccgtcg
    22261 tatcggaaag cggggacatt ttgtcgccaa aaaatgcgcc cgaaacaatc gcgcccgccg
    22321 tcatcgccat atcggcctga aacgccgccg ccatacccat aaaggcaacg ccgacagtgg
    22381 cgcaggtggt caggctgctg ccgatggaca cgccgatgac ggaacacagc gcgaaggcgg
    22441 aaaaataaaa ataagtcgga gaaatcagcc cgaaaccgta atacatcagc gtcggaatcg
    22501 caccgctcat catcagtgcg ctgaccatca gcccgatgaa gaaaaacagg taaatcgcgc
    22561 ccataccctg attcaacgcg cctatcatgc cctgctgcat atcgttgtat ttcaaaccgc
    22621 gcgccaagcc gtacaaaatc agcacgacga tggcggcaat aatggacata tgcggcagcc
    22681 actccaatga aatgatggta tagcccatcg cggcaatcag agcgacgacg acggcaagtg
    22741 cctcaccgcg cggcatatcg agtaaggatt tgaaagcaaa catgattctt tgcccgattt
    22801 gatataaagt taacggattc taacacacca taccgaatcc gcccaacgtt ttcagacggc
    22861 attttagcgt tttacaaaag ccggacagaa acaaaacggc aattttctca atttaaatta
    22921 atttttttga aatataattt tttatttttt tgtttgttgg catataagac ttttatggat
    22981 tgaagtatta aaacctcggc acacacgccg caaacaccgg tacgcaaaaa tgccgtctga
    23041 aagatgttca gacgacattt ctcaagaaaa agattatttg tccgccctat atccgtacac
    23101 cgcaaaaaac acgatataca gataacagat gacggaaacg acaaacgaag acatcagggt
    23161 gtaagtatct gccacccagc cctgcacgac aggaacgacc gcaccgccga caatcgcggt
    23221 acacagtaca ccggaagccg cgttggtaaa ttttcccaat cctttggttg ccaaagagaa
    23281 aatcgtcggg aacataatcg agttgaaaaa accgatggca agcagcgacc acatcgccac
    23341 atccgcattg ccgctacccg tcgccatcgc gacggcaagc agtacgaccg cagccgatgc
    23401 gttaaacgcc aaataacggt tgggcgcgaa tttcgccatc accgccgaac cgaggaaacg
    23461 tccgaccatc gcgccgcccc aatagaacga caggtaatgc gcggcagaag catgatccag
    23521 ccctttcaga taacccaata cgttgaccat caacgaaccg atagacacct ccgcgccgac
    23581 atagcagaaa atgcctgccg taccgaacac gagatgtttg tattgccata cgctggtttt
    23641 gccgtcgtgg ttgtgcgcgc tttcctcggc ggcaattttg cgcgcgtcgg gcagccggat
    23701 cattttcacg aaaacggcaa ggataatcag cagccccgcc agtcccaaat agggaatctg
    23761 tacggaagaa atctgttccg ccttgctgac ggtttgggtt gcgtccgcca gaatcaggaa
    23821 cgcgccgatt tgcggcgcaa tggtcgtacc caaagcgtta aacgcctgaa ccagcgtcag
    23881 tgttgccgat tccttgccgg gtttcgccag cagggtaaca taaggattac cggcgacctg
    23941 aagcagcgtt acgccggaag ccaaaataaa caacgcgccc aaaaataccg cgtaagaatg
    24001 gctgcccgca gcaggataaa acagcaggca tccgaccgcc gtcagcagaa agccgccgat
    24061 aacgccgttt ttgtagccga ctttgccgac aaaagccccc atcgggatgg acatcaccgc
    24121 ataggcggta aagaaacaga attggatcag catcgcctga acgtaagaca ggtcgaaaat
    24181 ttctttcaaa tgagggataa ggatgtcgtt catgcaggta ataaaaccca tcatgaagaa
    24241 cagcgtggtc aagacgacca atggggacgt atgattgttt tgtgattgcg cagacatgat
    24301 ttgcctttcg tggtgtcgga atattacccg tttcaagaaa atagaaattg acatttctta
    24361 acggcaatgc aaatcatact gatatttgaa cattttgcaa actttatcgg atgcaggcaa
    24421 tgcgccgatc tgaaattcaa gcagcagaaa ttaatatttt acagttgctt gcatagattt
    24481 taatagattt taatagattt taaaaaattc cggcggactt gcaaaaaccg ttcccaataa
    24541 aatgaaaatc cgccgccgta tccggaaaat tcggaaatgc cgcatcgtgg catcaaaacc
    24601 ggagcggaaa gaatgtcgta tgcccgacaa aaaaggggca tacggctgtg ccgtattttt
    24661 tgcaccgtcc tccgcccttc ggcgggggcg tgaaaatata gtggattaac aaaaatcagg
    24721 acaaggcgac g
//
LOCUS       DAXIDM010000019        23964 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000019 DAXIDM010000000
VERSION     DAXIDM010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23964
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.019"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..190)
                     /locus_tag="ACFOAE_000640"
     CDS             complement(<1..190)
                     /locus_tag="ACFOAE_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884176.1"
                     /translation="MPSERLSDGIFPCVLNRIHETPDAFGGNVGCRAMFGGDQRTKYA
                     GKGLMPSEGSDGIGVGESE"
     gene            complement(208..765)
                     /locus_tag="ACFOAE_000641"
     CDS             complement(208..765)
                     /locus_tag="ACFOAE_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFC6884177.1"
                     /translation="MDALKLLTNRRSSKKLKHPAPDAAELEQIFQAATQVPDHGNMRP
                     FRFTVIQGEVGLQRFRDVLKQTVAELNFGDDAMKKAEKVGNMAPMVIGVTFAPNRDVP
                     KPKPEWEQMLTAGCAAYALQLAATAQGFDNVWITGMWVNSPLLREAFGCADKDKIIGL
                     MMVGTPTEEVHKPKNTDLEAFVSHW"
     gene            complement(841..2475)
                     /locus_tag="ACFOAE_000642"
     CDS             complement(841..2475)
                     /locus_tag="ACFOAE_000642"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0009244 - lipopolysaccharide core region
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:1900727 - osmoregulated periplasmic glucan
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HFC6884178.1"
                     /translation="MIKPNLRPKLGSSALIAFLSLYSSLVLNYAFFAKVVELHPFNGT
                     GADIFLYTMPVVLFFLSNFVFHVIALPFVHKVLIPLILVISAAVSYQEIFFNIYFNKS
                     MLNNVLQTTAAESARLITPGYVLWIVCLGVLPALAYIAVKVKYRVWYKELLTRLVLAA
                     VSFLCALGIAMLQYQDYASFFRNNKSVTHLIVPSNFIGAGVSKYKDWKRSNIPYTQLD
                     MAVVQNRPAGSLRRFVVLVVGETTRAANWGLNGYSRQTTPLLAARGDEIVNFPQVRSC
                     GTSTAHSLPCMFSTFDRTDYDEIKAEHQDNLLDIVQRAGVEVTWLENDSGCKGVCGKV
                     PNTDVTSLNLPEYCRNGECLDNILLTKFDEVLNKNDKDAVLILHTIGSHGPTYYERYT
                     EAERKFTPTCDTNEINKCTRATLVNTYDNTVLYVDQFIDKVIRKLENRDDLESVVHYV
                     SDHGESLGENGMYLHAAPYAIAPSGQTHIPMVMWFSKAFRQHGGIDFQCLKQKAAENE
                     YSHDHYFSTVLGLMDISNSQTYRKEMDILAACRRPR"
     gene            complement(2545..2878)
                     /locus_tag="ACFOAE_000643"
                     /pseudo
     CDS             complement(2545..2878)
                     /locus_tag="ACFOAE_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221902.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2878..3984)
                     /gene="serC"
                     /locus_tag="ACFOAE_000644"
     CDS             complement(2878..3984)
                     /gene="serC"
                     /locus_tag="ACFOAE_000644"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004648 -
                     O-phospho-L-serine:2-oxoglutarate aminotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine transaminase"
                     /protein_id="HFC6884179.1"
                     /translation="MSLYPIYNFSAGPAVLPEAVLETARQEMLDYNGTGFPVMAMSHR
                     SEMFLSILHHAEQDLRQLLKVPDNYKILFLQGGATTQFNMAAMNLAHGFRTADAVVTG
                     NWSRIAYEQMSRLTDTEIRLAAHGGEQFDYLDLPPVETWDVAPDSAFVHFAVNETVNG
                     LQYREVPRLSEGMPPLVCDMSSEILSREFDVADYGLIYAGAQKNIGPAGATVVIIRED
                     LLERCPDDIPDVFNYRSHLNRDGMYNTPSTYAIYMSGLVFRWLQAQGGVKKIEAVNRL
                     KAQTLYETIDGSGGFYINRIRPNARSKMNVVFQTGDEELDRRFVLEAELQGLCLLKGY
                     KTVGGMRASIYNAMPLEGVRALADFMRDFQRRYG"
     gene            4349..4780
                     /gene="rimP"
                     /locus_tag="ACFOAE_000645"
     CDS             4349..4780
                     /gene="rimP"
                     /locus_tag="ACFOAE_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003685973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFC6884180.1"
                     /translation="MDIQTILEKTLPGLGYELVDFELTAQGTLRVFIDKESGITVEDC
                     ATVSNHLSRVFMVEDIDYKNLEISSPGLDRPLKKAADFVRFAGQNAKIKTRLPIDGQK
                     NFIGKIEGCENDTVTVSFDGKTVQIELGNIDKARLRPEFKF"
     gene            4808..6310
                     /gene="nusA"
                     /locus_tag="ACFOAE_000646"
     CDS             4808..6310
                     /gene="nusA"
                     /locus_tag="ACFOAE_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFC6884181.1"
                     /translation="MSREMLQLAEALASEKNVDAEVVFQALEFALSTAAKKKADREHM
                     DVRVQINRDTGEYQTFRRWLIVADEDYTYPDVEKTIEEIQEEIPGTTIQIGEYYEEQL
                     PNEGFGRQAAQTAKQIILQRIRDAEREQNLNEFLAVKEDIVSGTVKRVERHGIIVEVV
                     AGKLDALIPRDQMIPRENFRSGDRIRALFLRVEEIGNTGRKQVILSRTSGDFLVKLYA
                     NEVPEIADGMLEIRAVARDPGQRAKVAVKANDQRIDPQGTCIGVRGSRVNAVSNELSG
                     ERIDVVLWSPEPAQFVMSALSPAEVSRIVIDEDKHAVDVIVAEDQLALAIGRGGQNVR
                     LASDLTGWQLNIMTSAEADERNAAEDAAIRRLFMDHLNVDEETADVLVQEGFATLEEV
                     AYVPAAELLAIEGFDEEIVDMLRNRARDAILTMAIAAEEKLGEVSDDMRNLEGIDADM
                     LRSLAEAGITTRDDLAELAVDELIEITGVNEETAKAVILTAREHWFTEDK"
     gene            6323..9211
                     /gene="infB"
                     /locus_tag="ACFOAE_000647"
     CDS             6323..9211
                     /gene="infB"
                     /locus_tag="ACFOAE_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFC6884182.1"
                     /translation="MSNTTVEQFAAELKRPVEDLLKQLKEAGVSKNSGSDSLTLDDKQ
                     LLNAYLTKKNGSNGGTISIRRTKTEVSTVDGVKVETRKRGRTVNIPSAEELAAQVKAA
                     QTQAAPVRPEQTAEDTAKARAEAAARAEARAKAEAEAAKLKAAKAGNKAKPAAQKPTE
                     AKAETAPVAAETKPAEESKAEKAQADKMPSKKPAEPKEKAAKPKHERNGKGKDAKKPA
                     KPAAPAVPQPVVSAEEQAQRDEEARRAAALRAHQEALLKEKQERQARREAMKQQAEQQ
                     AKTAQEAKTGRQRPAKPAEKPQAAAPAVENKPVNPAKAKKEDRRNRDDEGQGRNAKGK
                     GGKGGRDRNNARNGDDERVRGSKKGKKLKLEPNQHAFQAPTEPVVHEVLVPETITVAD
                     LAHKMAVKGVEVVKALMKMGMMVTINQSIDQDTALIVVEELGHIGKPAAADDPEAFLD
                     EGAEAVEAEALPRPPVVTVMGHVDHGKTSLLDYIRRTKVVQGEAGGITQHIGAYHVET
                     PRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIAHAKAAGVPM
                     VVAVNKIDKEAANPERIRQELTAHEVVPDEWGGDVQFIDVSAKKGLNIDALLEAVLLE
                     AEVLELTAPVDAPAKGIIVEARLDKGRGAVATLLVQSGTLKKGDMLLAGTAFGKIRAM
                     VDENGKSITEAGPSIPVEILGLSDVPNAGEDAMVLADEKKAREIALFRQGKYRDVRLA
                     KQQAAKLENMFNNMGETQAQSLSVIIKADVQGSYEALAGSLKKLSTDEVKVNVLHSGV
                     GGITESDVNLAIASGAFIIGFNVRADASSRKLAENENVEIRYYNIIYDAIDDVKAAMS
                     GMLSPEEKEQVTGTVEIRQVISVSKVGNIAGCMVTDGVVKRDSHVRLIRNNVVIHTGE
                     LASLKRYKDDVKEVRMGFECGLMLKGYNEIMEGDQLECFDIVEVARTL"
     gene            complement(9422..10816)
                     /locus_tag="ACFOAE_000648"
     CDS             complement(9422..10816)
                     /locus_tag="ACFOAE_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase/DUF3482 domain-containing protein"
                     /protein_id="HFC6884183.1"
                     /translation="MNKQPLSLAVVGHTNTGKTSLLRTLLRDSGFGEVRNAPSTTRHV
                     EEAAISDGADTLVFLYDTPGLEDAGGVLEWLENHTDNRSDGIERLQQFLGSHGAHHDF
                     NQEAKVLRQVLQSDMAMYVIDAREPVLDKYRDELTILSWCAKPVMPVFNFTGGQPPES
                     WTTMLARRNLHVFAGFDTVAFDFEGELRLWENLATMLPERSTLDRLTAMRRREWQRLD
                     GEARREIADFLIDAAAFRQEVDENEDTATVLQTMQAEIRQLERQMQQRLFALYRFYHS
                     EIDGGDWMPQAFRQDPFDSELLKQYGIRTGTGAATGALIGLGLDIATLGGSLGLGTAI
                     GGFLGGILPNTRTISDKLSGRQTLHTDPETLTLLAARALDLLHVLQTRGHAAQSDIEL
                     HSRKAPWDAARLPPELNKARSHWKWSSLNTHRPETSRAERAGYVEKLQIRLSGKYSEL
                     NLNQDKAASRRQYK"
     gene            complement(10890..12230)
                     /locus_tag="ACFOAE_000649"
     CDS             complement(10890..12230)
                     /locus_tag="ACFOAE_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2868 domain-containing protein"
                     /protein_id="HFC6884184.1"
                     /translation="MLNPSRKLVELIRILDEGGFIFSGDPVQATEALRRVDGSTEEKI
                     IRRAEMIDRNRMLRETLERVRAGSFWLWVAAATFAFFTGFSGTYLLMDNQGLNFFLVL
                     AGVLGMNTLMLAVWLAMLFLRVKVGRFFSSPATWFRGKDPVNQAVLRLYADEWRQPSV
                     RWKIGATSHSLWLCTLLGMLVSVLLLLLVRQYTFNWESTLLSNAASVRAVEMLAWLPA
                     KLGFPVPDARAVIEGRLNGNIADARAWSGLLVGSIACYGILPRLLAWAVCKILLKTSE
                     NGLDLEKPYYQAVIRRWQNKITDADTRRETVSAVSPKIVLNDAPKWAVMLETEWQDGE
                     WFEGRLAQEWLDKGVAANREQVAALETELKQKPAQLLIGVRAQTVPDRGVLRQIVRLS
                     EAAQGGAVVQLLAEQGLSDDLSEKLEHWRNALAECGAAWLEPDRAAQEGRLKDQ"
     gene            12373..12999
                     /locus_tag="ACFOAE_000650"
     CDS             12373..12999
                     /locus_tag="ACFOAE_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFC6884185.1"
                     /translation="MYTGERFNTYSHLSGLILAAAGLALMLLKTIGHGDGYRIFSVSV
                     YGISLLLLYLSSSLYHGIAAGKLKSILKKTDHCMIYVLIAGSYTPFALVSLRNGPGWT
                     VFSLSWLLAAAGIAQELTIGRKSEKRLLSIAIYVVMGWMVLAVMKSLTASLPPAGLAW
                     LAAGGMLYSVGIYWFVNDEKIRHGHGIWHLFVLGGSITQFVSVYGYVI"
     gene            complement(13063..14481)
                     /locus_tag="ACFOAE_000651"
     CDS             complement(13063..14481)
                     /locus_tag="ACFOAE_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC6884186.1"
                     /translation="MENILSVLVGTVNRFLWDYLLIYALLGIGLFFTLYLGAPQITKL
                     GAGFKSVFGGLFAKGDKDDKSLSQFQALAVAISAQIGTGNVAGVATAITAGGPGAIFW
                     MWVSAVLGMSTIFAEALLAQKYRVVSHGKYIGGPAFYITHGLTPKIGRGAARFLSGFF
                     SIALIIALGFIGNATQANSIASAVTIAFDVPSLAVGIVLAVLAGMVVIGGVNRIANIA
                     QFVVPFMAVVYILCAVVILFEFSDHIVPMFNHIFTAAFNPEAVLGGAAGIGMREAVRF
                     GVARGLFSNEAGMGSTPHAHATADVKHPVQQGMAAFVGVFIDTILVCTATALIILLTD
                     ANLSGEQGAAVTQFAFNKAFPGFGSQLLAVCLTFFALTTIIGWYYFGESNIRFLFRGR
                     HLGIYRALVLLAIVLGTLGKVDLVWSLSDMFNGFMVIPNLIALFLLRKEIRAIYDDYL
                     AQKKAGRDLSYQYEFHEFHDKG"
     gene            14808..15536
                     /locus_tag="ACFOAE_000652"
     CDS             14808..15536
                     /locus_tag="ACFOAE_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004285004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFC6884187.1"
                     /translation="MAGHSKWANIQHKKARQDAKRGKIFTRLIKEITVAARMGGGDPG
                     SNPRLRLALEKAAENNMPKDNVQRAIDKGTGNLEGVEYIELRYEGYGIGGAALMVDCL
                     TDNKTRTVADVRHAFTKNGGNLGTDGCVAFNFVHQGYLVFEPGVDEDALMEAALEAGA
                     EDVVTNDDGSIEVITAPNDWAGVKSALEAAGYKSVDGDVTMRAQNETELSGDDAVKMQ
                     KLIDALEDLDDVQDVYTSAVLNLD"
     gene            complement(15595..16083)
                     /locus_tag="ACFOAE_000653"
     CDS             complement(15595..16083)
                     /locus_tag="ACFOAE_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein B"
                     /protein_id="HFC6884188.1"
                     /translation="MTPLFRKAVWLLFAVSVCAFAGSLAAQYVLGMEPCVLCISQRLC
                     VLATALCTAIVLMCRPRRRAGGLFGAVFISIPAVTGISVAAYQLWLQSLPPGTAPSCG
                     APWTFRLKGWSLFDWFEPVVRGFGNCAEPDYLLGVALPVWSAAYFLAVVLTVWWAWAR
                     AK"
     gene            complement(16842..17306)
                     /locus_tag="ACFOAE_000654"
     CDS             complement(16842..17306)
                     /locus_tag="ACFOAE_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFC6884189.1"
                     /translation="MKELDKIDFRILKILQQNARIPMTELAEKVGLSTTPVTERVRRL
                     EREHYISGYHAHLNPHLLGKPLLVFVELKLQSKSGNIFEDFKKEVLKIPQIMECHLVS
                     GEYDYLIKVRLPDMSAYRDMLGNILLQLPAASESRSYVVMEEVKENPVLDLD"
     gene            complement(17316..17446)
                     /locus_tag="ACFOAE_000655"
                     /pseudo
     CDS             complement(17316..17446)
                     /locus_tag="ACFOAE_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            17631..18689
                     /gene="alr"
                     /locus_tag="ACFOAE_000656"
     CDS             17631..18689
                     /gene="alr"
                     /locus_tag="ACFOAE_000656"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFC6884190.1"
                     /translation="MRPLNVQIRLGNLRHNYRILKEMHGGKLLAVVKADAYGHGAVRC
                     AFALADLADGFAVATIDEGIRLRESGITHPIVLLEGVFEASEYEAVEQYSLWPAVGNQ
                     WQLEALLSRHWKKPVKVWLKMDSGMHRTGFFPHDYASAYAALKQSEYVDSIVKFSHFS
                     CADEPESGMTEIQMEAFDLGTEGLEGEESLANSAAILNVPEARRDWGRAGLALYGISP
                     FGGSDDRLKPVMRLSTRIFGERVLQPHSPIGYGATFYTSKSTRVGLIACGYADGYPRR
                     APSNSPVAVDGKLTRVIGRVSMDMMTIELDASQEGLGHEVELWGDTVNINTVAEAAGT
                     IPYELMCNIKRAKFTYIE"
     gene            complement(18753..20108)
                     /locus_tag="ACFOAE_000657"
     CDS             complement(18753..20108)
                     /locus_tag="ACFOAE_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HFC6884191.1"
                     /translation="MSIQSGEILETVKMVADQNFDVRTITIGIDLHDCISSDINVLNQ
                     NIYNKITTVGKDLVATAKYLSAKYGVPIVNQRISVTPIAQIAAATHADSYVSVAQTLD
                     KAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMKTTDIVCSSINVGSTRAGINM
                     DAVKLAGETIKRTAEITPEGFGCAKIVVFCNAVEDNPFMAGAFHGSGEADAVINVGVS
                     GPGVVKAALENSDATTLTEVAEVVKKTAFKITRVGELIGREASKMLNIPFGILDLSLA
                     PTPAVGDSVARILEEMGLSVCGTHGTTAALALLNDAVKKGGMMASSAVGGLSGAFIPV
                     SEDEGMIAAAEAGVLTLDKLEAMTAVCSVGLDMIAVPGDTPAHTISGIIADEAAIGMI
                     NSKTTAVRIIPVTGKTVGDSVEFGGLLGYAPVMPVKEGSCEVFVKRGGRIPAPVQSMK
                     N"
     gene            complement(20123..20395)
                     /locus_tag="ACFOAE_000658"
     CDS             complement(20123..20395)
                     /locus_tag="ACFOAE_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HFC6884192.1"
                     /translation="MNNSVITVIGKDRVGIVYDVSKILAENRINILNISQQLMDDFFT
                     MIILVDTSKCPKSRQEVLDLFAEESKKLALDIRMQNEEIFQAMHRI"
     gene            complement(20521..21258)
                     /locus_tag="ACFOAE_000659"
     CDS             complement(20521..21258)
                     /locus_tag="ACFOAE_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system YwqK family antitoxin"
                     /protein_id="HFC6884193.1"
                     /translation="MKKLSRIVFSIVLLGFSASLSAQTYSVYFNQNGKLTATMSSAAY
                     IRQYSVAEGIAYAQDFYYPSMKKYSEPYIVASTQIKSFVPTLQNGMLILWHFNGQKKM
                     AGGFSKGKPDGEWVNWYPNGKKSAVMPYKNGLSEGTGYRYYRNGSKESEIQFKQNKAN
                     GVWKQWYADGNIKTEMVMVNDEPAKILTWDESGRLLSELSIHHHKRNGVVLEWYEDGS
                     KKSEAVYQDDKLVRKTQWDKDGYLIEP"
     gene            complement(21539..22438)
                     /gene="prmB"
                     /locus_tag="ACFOAE_000660"
     CDS             complement(21539..22438)
                     /gene="prmB"
                     /locus_tag="ACFOAE_000660"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008276 - protein methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA];
                     GO_process: GO:0042273 - ribosomal large subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFC6884194.1"
                     /translation="MFNQAAQELTTIRDVLRFAVSRFNEAGLFFGHGTDNAHDEAAYL
                     ILHTLNLPLDMLAPYLDAKLLEAEKEEVLTVIERRAVEHIPAAYLTHQAWQGEFDFYV
                     DERVIIPRSFIYELLGDGLRPWIEYDELVHNALDLCTGSGCLAIQMAHHYPDAQIDAV
                     DVSLDALEVAGINVEDYGLEERIRLIHTDLFEGLEGTYDLIVSNPPYVDAESVELLPE
                     EYLHEPELALGSGADGLDATRQILLNAAKFLNPKGVLLVEIGHNRDVLEAAYPELPFT
                     WLETSGGDGFVFLLTREQLLGEE"
     gene            22583..23176
                     /locus_tag="ACFOAE_000661"
     CDS             22583..23176
                     /locus_tag="ACFOAE_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884195.1"
                     /translation="MADGMGNLIGWEKTGLVAGKQWITAKDDKVSDVCNANGEMGVIG
                     LYEPFSHGALTIPGHPNCRCEVVSVSGGELGEFAEKKELRKAAMQYARDNFIGKSYVN
                     ENSGHELKVTWQGVKHAASKANQAELSIMTKLDDLLRYAKYEGSYSDRKGHPNIIAAH
                     KYRAVAKVGNESLNIGVIVREFPDDHKHYDHFILKDE"
     gene            23288..23908
                     /locus_tag="ACFOAE_000662"
     CDS             23288..23908
                     /locus_tag="ACFOAE_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFC6884196.1"
                     /translation="MTKLYAEIAKMETQDDDTVKVWGYASSEEIDSDGEVIATAAMKA
                     AIPDYMKFGEGREMHGSNAAGTAIEINVEDDGITFFGAHIIDPVVVAKVKTGVYKGFS
                     IGGSVTARDDLNKSQITGLKLTEISLVDRPANPDAVFTCFKADKGAEAVNNDTEHNAT
                     YFSHFPSKQKSTGGSRCPFLYRFPYFLSAGSTGLAGPFGAGAPTEA"
BASE COUNT         6329 a         6517 c         5905 g         5213 t
ORIGIN      
        1 cttctgattc cccgacaccg atgccgtctg aaccttcaga cggcatgaga cctttgcctg
       61 cgtacttggt gcgctggtcg cctccgaaca tggcgcgaca cccgacattt ccgccgaacg
      121 catcgggcgt ttcatgaatc cggtttaaaa cgcatggaaa aatgccgtct gaaagccttt
      181 cagacggcat tttgcttgag attccgttta ccaatggctg acaaacgctt ccaaatcggt
      241 attcttgggc ttatgcactt cctctgttgg cgtgccgacc atcatcagcc cgatgatttt
      301 atccttatcc gcacaaccga aagcctcccg caacaagggg ctgttgaccc acatccccgt
      361 aatccaaaca ttgtcgaatc cctgagccgt tgccgccagt tgcagcgcat acgccgcaca
      421 acccgccgtc agcatctgct cccattccgg tttcggctta ggcacatcgc ggttcggcgc
      481 aaacgttacc ccgataacca tcggcgccat attgcccact ttttccgcct ttttcatcgc
      541 atcgtcgccg aaattcaatt cggcaaccgt ttgcttcaac acatcgcgaa aacgttgcaa
      601 tcctacctcg ccttgaatca cggtaaaacg gaaggggcgc atattgccgt gatcgggaac
      661 ttgggttgcc gcctgaaata tttgttccaa ctccgccgca tcgggggcgg ggtgcttcag
      721 ctttttggaa gatcggcggt tcgtcaataa ttttaaagca tccatatcgt tatactccgg
      781 tcatcggtcg ggtgttcgga cacatatgcc gtccgaaggc ttcagacggc atatccggca
      841 tcagcgcgga cggcggcagg ctgccaatat atccatttcc ttccgatagg tttggctgtt
      901 ggaaatgtcc atcagcccca ataccgtgct gaaatagtgg tcgtgcgaat attcgttttc
      961 cgccgctttt tgtttgaggc attggaaatc tatgcccccg tgttggcgga aggctttgga
     1021 aaaccacata accatcggga tatgcgtctg cccggaaggc gcgatggcgt aaggcgcggc
     1081 gtgcaggtac atcccgtttt cgcccaaact ttcgccgtgg tcggaaacat aatgcaccac
     1141 gctttccaaa tcgtcgcggt tttcaagttt gcggataacc ttgtcgataa actggtccac
     1201 atacaaaacc gtattgtcgt aagtgttgac cagcgtggcg cgggtgcatt tgttgatttc
     1261 gttggtgtcg caggtcggcg tgaatttgcg ttcggcttcg gtatagcgtt cgtaatacgt
     1321 cggcccgtgg ctgccgatgg tatgcaggat taaaaccgcg tctttatcgt ttttgttgag
     1381 gacttcgtcg aacttagtca gcaggatatt gtcgaggcac tcgccgttgc ggcagtattc
     1441 gggcaggttg agcgaggtaa cgtcggtatt cggcactttg ccgcacacgc ccttgcagcc
     1501 ggaatcgttt tccaaccagg taacttccac gccggcgcgc tgcacgatgt ccagcaggtt
     1561 gtcttggtgt tcggctttga tttcgtcata atccgtgcgg tcgaaggttg agaacataca
     1621 cggcagggag tgcgcggtcg atgtgccgca gcttctgacc tgcgggaaat tgacaatttc
     1681 atcgccgcgc gcggcaagca gcggcgtagt ttggcggctg taaccgttca aaccccagtt
     1741 ggcggcacgc gtggtctcgc ccacgaccag caccacgaaa cggcgcaggc tgccggccgg
     1801 ccggttttgc acgaccgcca tatccaattg cgtataagga atattggaac gcttccaatc
     1861 tttgtatttc gacacgcccg cgccgatgaa attagacggc acaatcagat gggttactga
     1921 tttattgttg cggaaaaacg aggcgtaatc ctgatattgc aacattgcga tgcccaacgc
     1981 gcacaaaaag gaaacggcgg caagcacaag gcgcgtcaaa agctccttat accaaacgcg
     2041 gtatttaacc ttgacggcga tatacgccag cgcaggcaat acgcccaaac atacaatcca
     2101 cagcacatag cccggcgtaa tcaggcgcgc gctttcggca gccgtagttt gcaagacatt
     2161 attcaacatc gacttgttga aatagatatt gaaaaatatt tcttggtaag acaccgccgc
     2221 actgataacc aatatcaacg gaatcaatac cttatgcacg aaaggcaggg caatgacgtg
     2281 aaaaacgaaa ttacttaaaa aaaacagcac caccggcatc gtatagagga agatatccgc
     2341 cccggtgccg ttaaaaggat gaagctcgac aactttggca aaaaaggcgt aattcaatac
     2401 cagcgaggaa tacagggaaa ggaaggcaat cagcgcggaa gagccgagct tcggcctcag
     2461 gttcggtttt atcatttgga atgtgtcgga taagggttgg aaaaggcatc cggcatttgg
     2521 aatccggatt attgaaaaag attcttaatt ataaggcaac ggagcaaagc agggcaagaa
     2581 aacggcggct gtgcgggggg ttccgcccgc cattcaaacg tccggcagac ataaaaacat
     2641 cgtaagcaag attcgaaccg gtctgcaacc gcccctgcca gaaaaacggg caaagcattt
     2701 catattggaa aaacccggcc gcgccgccga cgggacagtc cggcacaaac agcatcacgc
     2761 ccggattgaa aaggacggat agccgccggc agcacaatct taccacctcc aaaacgccgc
     2821 cggagaacgc cgaaacagcc gatgccgtct gaagccgctt cagacaacat cgggacatca
     2881 accgtaacgc cgttggaaat cgcgcataaa atccgccaaa gcccgcacgc cttcaagcgg
     2941 catcgcatta taaatgctgg cacgcatacc gccgacggtt ttatagccct taagcaggca
     3001 caagccctgc aattcggctt ccagcacaaa acggcggtca agctcctcat cccccgtttg
     3061 gaacacgaca ttcattttag aacgcgcatt cggacggata cggttgatat agaaaccgcc
     3121 gctgccgtct atcgtctcat acaaggtttg cgccttcagc cgattgaccg cttcaatttt
     3181 tttcacaccg ccctgcgcct gcagccagcg gaacaccagc cccgacatat aaatcgcgta
     3241 agttgacggc gtgttgtaca taccgtcgcg gttcaaatgc gaacggtagt tgaacacatc
     3301 gggaatatcg tccgggcaac gttccagcaa atcctcgcgg ataatgacca cggtcgcacc
     3361 ggccgggccg atgtttttct gtgcgcctgc gtaaatcagt ccgtagtcgg caacatcaaa
     3421 ctcgcgcgac aaaatctcgc tggacatatc gcacaccagc ggcggcatgc cttctgaaag
     3481 gcgcggcact tcacggtatt gcagcccgtt gaccgtttca ttgacggcaa aatggacaaa
     3541 cgccgaatcg ggtgcaacat cccacgtttc cacaggcggc aggtcgagat agtcgaactg
     3601 ctcgccgcca tgcgccgcca aacggatttc cgtatcggtc aaacggctca tctgttcata
     3661 agcgatacgg ctccagttgc ccgttaccac cgcgtcggca gtgcggaaac cgtgtgccag
     3721 attcatggct gccatattaa attgggttgt tgctccgccc tgcagaaaca atatcttata
     3781 gttgtcaggc actttcaaaa gctgcctcaa atcctgttcc gcatgatgca ggatgctcaa
     3841 aaacatttcc gaacggtggc tcatcgccat cacgggaaaa cccgtaccgt tgtagtccaa
     3901 catttcctgc cgcgccgttt ccaacacggc ttcgggcaat acggcagggc cggcggaaaa
     3961 attgtaaatc ggataaagag acatgatgca gccttgattc tgaacaataa cccgcctgat
     4021 tttaggcttg cagcaggctt tgtgcaagga tgggaaatac ctgtcctccg ccccgcttca
     4081 tgccgcccga acacggaaaa caacatcaat atattgattt acaaatataa aaatcatgct
     4141 agcgacaaat agatacattt gttttgtcaa caatattcac gatttcccat tacaaacctc
     4201 ccttacaccc gcttttttcc gtcccaaaaa cacaaaataa atcaacactt tcatttctcc
     4261 gcaaaagcgg ttataatcac gccgattttt caactttgac gaaaaatggc cacgaggcca
     4321 tttttttatt atgtacatag ggagcagcat ggatatccaa accatcctcg aaaaaaccct
     4381 gcccggcctg ggctacgaac tggtcgattt cgaactgacc gcgcaaggaa cattgcgcgt
     4441 gttcatcgac aaagaaagcg gcattaccgt cgaagactgc gcaaccgtca gcaaccactt
     4501 gagccgcgtc ttcatggttg aagacatcga ctacaaaaac ctggaaattt ccagccccgg
     4561 actcgaccgc cccttgaaaa aagccgccga cttcgtgcgc tttgccggtc agaatgccaa
     4621 aatcaaaacc cgcctgccga tagacggtca gaaaaacttt atcggtaaaa tcgaaggctg
     4681 cgaaaacgat accgttaccg tatccttcga cggcaaaacc gtacaaatcg aattgggcaa
     4741 catcgacaaa gcccgtctgc gccccgaatt caaattctaa aacacaacaa tattggagat
     4801 gttcaaaatg agtcgtgaaa tgttacagct ggcagaagca ctggcaagcg aaaaaaacgt
     4861 tgatgcggaa gtcgtcttcc aagcactgga attcgccctg tctaccgccg ccaagaaaaa
     4921 ggcagaccgc gaacacatgg acgtgcgcgt ccaaatcaac cgcgacaccg gcgaatacca
     4981 aaccttccgc cgctggctga ttgtcgccga tgaagactat acctatcccg atgtcgaaaa
     5041 aaccatcgag gaaatccaag aggaaattcc cggcactacc atccaaatcg gcgaatacta
     5101 cgaagagcag ctgcccaacg aaggcttcgg ccgccaagcc gcgcaaaccg ccaaacaaat
     5161 catcctgcaa cgcatccgcg atgccgagcg cgagcagaat ctgaacgagt ttctcgccgt
     5221 caaagaagac atcgtgtctg gcacggtcaa acgcgtcgaa cgccacggca tcatcgtcga
     5281 agtcgttgcc ggcaaactgg acgcgctgat tccgcgcgac caaatgattc cgcgcgaaaa
     5341 cttccgcagc ggcgaccgca tccgcgccct cttcctgcgc gtcgaagaaa tcggcaacac
     5401 cggccgcaaa caagtcatcc tgagccgtac ttccggcgat ttcctcgtca aactgtacgc
     5461 caatgaagta cctgaaattg cagacggcat gcttgaaatc cgcgctgtcg cccgcgaccc
     5521 gggccaacgt gccaaagtcg ccgtcaaagc caacgaccag cgcatcgatc cgcaaggcac
     5581 ctgtatcggc gttcgcggtt cgcgtgtcaa tgccgtcagc aacgaattgt ccggcgagcg
     5641 catcgacgtt gtcctttggt cgcccgagcc tgcccaattc gtcatgagcg cgctctcacc
     5701 cgccgaagtc agccgcatcg tcatcgacga agacaaacac gccgtcgatg tcatcgttgc
     5761 cgaagaccag ctcgcgctcg ccatcggacg cggcggtcaa aacgtgcgcc ttgcttccga
     5821 cctgaccggc tggcagctca acatcatgac ttccgccgag gcagacgaac gcaatgcggc
     5881 agaagatgcc gccatccgcc gcctgtttat ggatcacttg aacgtggacg aagaaaccgc
     5941 cgacgtactg gttcaggaag gttttgcaac cttggaagaa gtcgcctatg ttcctgccgc
     6001 cgaactgctt gccattgaag gatttgacga agaaatcgtc gatatgctcc gcaaccgcgc
     6061 ccgcgatgcc atcctgacca tggcgattgc cgccgaagaa aaactgggcg aagtatccga
     6121 cgatatgcgc aacctcgaag gcatagatgc cgatatgctc cgcagccttg ccgaagcagg
     6181 cattaccacc cgcgacgact tggcagagct tgctgtggac gaactgattg aaatcaccgg
     6241 tgtaaacgaa gaaaccgcaa aagccgtcat cctgaccgca cgcgaacact ggtttaccga
     6301 agacaaataa aagggggtac agatgagtaa cacaaccgta gaacaatttg ccgccgagct
     6361 gaaacgcccc gtcgaagacc tgttgaaaca gttgaaagaa gccggcgtca gcaaaaacag
     6421 cggcagcgat tccctgacgc tggacgacaa acagcttctg aacgcctacc tgaccaagaa
     6481 aaacggcagc aacggcggca ccatcagcat ccgccgcacc aaaaccgaag tcagcaccgt
     6541 tgacggcgta aaagtcgaaa cacgcaaacg cggacgcact gtcaacattc cttctgccga
     6601 agaattggca gcacaggtaa aagccgccca aacccaagcc gcacctgtcc ggccggagca
     6661 gacggcagaa gacacggcaa aagcccgagc cgaagctgcc gcacgtgcag aagcccgtgc
     6721 caaggcagaa gcggaagcgg caaaactgaa agcggcaaaa gcaggcaaca aagccaaacc
     6781 tgccgcgcag aaacccaccg aagcaaaagc cgaaaccgca cctgttgcgg cggaaaccaa
     6841 acccgccgaa gaaagcaaag cggaaaaagc ccaagccgac aaaatgccgt ctaaaaaacc
     6901 cgccgagccc aaagaaaaag ccgccaagcc gaaacacgag cgaaacggca aaggcaaaga
     6961 tgccaaaaaa ccagcgaaac ctgccgcacc tgccgtgccg caacccgtgg tcagcgcaga
     7021 agaacaggcg caacgcgatg aagaagcacg ccgtgccgcc gcacttcgcg cccaccagga
     7081 agccctgttg aaagagaaac aggaacgcca ggcacgccgc gaagccatga aacaacaggc
     7141 agaacaacag gcaaaaaccg cacaggaagc caaaaccggc agacagcgtc ccgccaaacc
     7201 tgccgagaaa ccgcaggcag ccgcgccggc cgtcgaaaac aagcctgtca atccggcaaa
     7261 agcgaaaaaa gaagaccgcc gcaaccgcga tgacgaaggt caaggccgca acgccaaagg
     7321 caaaggcgga aaaggcgggc gcgaccgcaa caatgcacgc aacggcgacg acgagcgcgt
     7381 acgcggcagc aaaaaaggca aaaaactcaa actcgagccg aatcaacacg ccttccaagc
     7441 accgaccgaa cccgtcgttc atgaagtttt ggttcccgaa accattaccg ttgccgattt
     7501 ggcgcacaaa atggcggtca aaggcgtgga agtggtcaaa gccctgatga agatgggcat
     7561 gatggttacc atcaaccaat ccatcgacca agacaccgcc ctgattgtgg tggaagaact
     7621 cggccacatc ggcaaacctg ccgcagccga cgaccctgaa gcattcttgg acgagggcgc
     7681 ggaagcggtg gaagccgaag cattgccgcg tccgcccgtc gttaccgtca tgggccacgt
     7741 cgaccacggc aaaacctcgc tgctggacta catccgccgt accaaagtgg tacagggcga
     7801 agcaggcggc attacccaac acatcggtgc ataccacgtt gaaaccccac gcggcgtgat
     7861 taccttcttg gatactccgg gtcacgaagc gtttactgcc atgcgtgcgc gcggtgcgaa
     7921 agcaaccgac atcgtgattc ttgtggtcgc cgccgacgac ggtgtgatgc cgcaaaccat
     7981 cgaagcgatt gcccacgcca aagcggcagg cgtaccgatg gtggttgccg tcaacaaaat
     8041 cgataaagaa gccgccaacc cagagcgtat ccgccaagag ctgaccgcac acgaagtcgt
     8101 gcctgacgaa tggggcggcg atgtacagtt tatcgacgtt tccgctaaaa aaggcctgaa
     8161 catcgatgca ttgctcgaag cagtcttgct cgaagccgaa gttttggaac tgactgcccc
     8221 tgtcgatgcg cccgccaaag gcatcatcgt tgaggcacgt ttggacaaag gccgcggcgc
     8281 ggttgccaca ttgctggttc aaagcggtac gctgaaaaaa ggcgatatgc tgctggccgg
     8341 tacggcattc ggcaaaatcc gcgcgatggt cgatgaaaac ggcaaatcca ttaccgaagc
     8401 cggcccgtcc atccccgtcg aaatcctcgg cttgtccgac gtaccgaatg cgggtgaaga
     8461 cgcgatggta ttggcggacg agaaaaaagc gcgcgaaatc gccctcttcc gccaaggcaa
     8521 ataccgcgac gtgcgccttg ccaaacagca ggcggcgaag ctggaaaata tgttcaacaa
     8581 tatgggcgaa acccaggccc aatctttgtc ggtcatcatc aaggcagacg tgcagggttc
     8641 ttacgaggct ttggcgggca gcctgaaaaa actgtccacc gacgaggtga aagtgaacgt
     8701 attacacagc ggcgtgggcg gcattaccga atcagatgtc aaccttgcca tcgcttcggg
     8761 cgcgttcatt atcggcttta acgtgcgtgc agatgcctct tcgcgcaaac ttgccgaaaa
     8821 tgaaaacgtg gaaatccgct actacaacat catctacgat gccatcgacg acgtgaaggc
     8881 ggcgatgagc ggcatgcttt ctccggaaga gaaagaacag gttaccggta cggtcgaaat
     8941 ccgtcaggtc atctccgttt ccaaggtcgg caacattgca ggctgtatgg ttaccgacgg
     9001 cgtggtcaaa cgcgattccc atgtccgcct catccgcaac aacgtggtca tccacacggg
     9061 cgaactggct tcgttgaaac gctataaaga cgacgtcaaa gaagtccgta tgggctttga
     9121 gtgcggcctg atgctcaaag gctacaacga aatcatggaa ggcgaccaac tggaatgctt
     9181 cgacatcgtc gaagtggcac gcaccctgtg attttgatgc ggaaaaatgc cgtctgaagc
     9241 gttcagacgg catacggaac gggttctgta tcatacagaa cccgtttttt atcgcaaatc
     9301 ggcttcagac agccctcctg ccttatcccg atttgaatct gacttgccat acaaacaggc
     9361 ttcagacggc attatagtga attaaattta aaccggtaca gcgttggctc gccttgccgt
     9421 actatttgta ctgtctgcgg ctcgccgcct tgtcctgatt taaatttaat tcactatatt
     9481 ttcccgacag gcggatttga agtttctcca catatccggc gcgttcggcg cggctggttt
     9541 cggggcggtg cgtattgagc gacgaccatt tccaatgact gcgggctttg ttgagttcgg
     9601 gcgggagtct ggcggcgtcc cacggggctt tgcggctgtg cagctcgata tccgactgtg
     9661 ccgcgtgtcc gcgcgtttgc aggacgtgga gcaaatcgag ggcgcgggcg gcgagcaggg
     9721 tcaaggtttc agggtcggtg tgcaaggttt ggcggccgga gagtttgtcg gaaatggtgc
     9781 gggtattggg caggatgccg cccaaaaagc cgccgattgc cgtacccaat ccgagcgagc
     9841 cgccgagtgt ggcgatgtcc agccccaagc cgatgagcgc gccggttgcc gcgcccgtgc
     9901 cggtgcggat gccgtattgt ttgagcaatt cgctgtcgaa cgggtcttgg cggaaggctt
     9961 gcggcatcca gtcgccgccg tcgatttcgc tgtggtagaa acggtagagg gcaaacagcc
    10021 gctgctgcat ctgccgttcg agttggcgta tttccgcctg catggtttgt agcacggtgg
    10081 cggtatcctc gttttcgtcc acttcctgcc tgaaggcggc ggcatcaatt aaaaagtcgg
    10141 cgatttcgcg gcgcgcttcg ccgtccagcc gctgccattc gcgccggcgc atggctgtca
    10201 ggcggtcaag tgtgctgcgt tcgggcaaca tggtggcgag gttttcccac aggcgtagtt
    10261 cgccttcaaa atcaaaggcg acggtgtcga accctgcgaa aacgtgcagg tttctcctcg
    10321 ccagcatggt tgtccacgat tcgggaggct gtccgccggt aaagttgaac acgggcataa
    10381 ccggtttggc acaccatgaa aggatggtca actcgtccct gtatttgtcg aggacgggtt
    10441 cgcgcgcgtc gatgacgtac attgccatat cgctttgcaa gacttgccgt aagactttgg
    10501 cttcctgatt gaaatcatgg tgcgcgccgt ggctgccgag aaactgttgc agccgttcga
    10561 tgccgtctga acgattgtcc gtatggtttt ccagccattc cagcacgccg cctgcgtctt
    10621 cgagtccggg cgtgtcgtac aggaaaacca gcgtgtctgc gccgtcgctg atggcggctt
    10681 cttcgacatg acgcgtggtc gatggggcgt ttctgacttc gccgaaaccg ctgtcgcgca
    10741 acagggtacg aaggagcgag gttttgccgg tgttggtatg cccgacgacg gcgagggaaa
    10801 ggggttgttt gttcatgatg tttttgaaga atggattttc agacggtctt ttttcagaat
    10861 ggcggcttaa cagaacattt caagtgagtt tattggtctt tcaaacgccc ttcctgcgcc
    10921 gccctgtcag gctcaagcca cgccgcgccg cattcggcca gcgcgttacg ccaatgttcc
    10981 agcttttccg aaaggtcgtc tgaaagcccc tgttccgcca aaagctgcac caccgcgccg
    11041 ccctgcgccg cttccgaaag tcggacgatc tgccgcaaca cgccgcggtc gggcacagtt
    11101 tgggcgcgca cgccgataag cagttgcgcc ggtttctgct tcagctctgt ctccagcgcg
    11161 gcaacctgtt cccgattggc ggcaacgccc ttatccagcc attcctgcgc cagcctgccc
    11221 tcgaaccatt cgccgtcctg ccattcggtc tccagcatga ccgcccattt cggcgcatcg
    11281 ttcaagacga ttttcggcga aacggcggac acggtttccc gacgcgtatc cgcatcggtg
    11341 attttgttct gccagcggcg gatgaccgcc tgataatagg gtttttccaa atccaatccg
    11401 ttttcgcttg ttttcaaaag gattttgcat accgcccaag ccaagaggcg cggcaggatg
    11461 ccgtagcagg cgatactgcc gaccagcagc cccgaccaag cccgcgcatc ggcaatattg
    11521 ccgttcagac gaccttcgat gaccgcccgc gcatcaggca cgggaaaacc cagtttcgca
    11581 ggcagccatg ccaacatttc caccgcgcgt accgaagcgg cattgctcaa cagcgtgctt
    11641 tcccagttga acgtatattg ccgcaccaaa agcagcaaca ataccgacac cagcattccg
    11701 agcagcgtgc agagccacag gctgtgcgac gttgcgccta ttttccaacg taccgaaggt
    11761 tgccgccact cgtccgcata cagccgcaac accgcctgat ttacagggtc tttgccccga
    11821 aaccacgtcg ccggactgct gaaaaaacgc cccactttca cgcgcaggaa caacattgcc
    11881 aaccatactg ccagcatcag cgtattcatg cccaacacgc ccgccaaaac caaaaagaaa
    11941 ttcagaccct gattgtccat tagaagataa gtacctgaaa aaccggtaaa aaacgcaaac
    12001 gtcgccgccg ccacccacaa ccagaacgac cccgcacgca cacgttccaa cgtctcccgc
    12061 agcatacggt tcctgtcaat catctccgcc cgacggatga ttttttcctc cgtactgccg
    12121 tccacgcggc gcaaagcctc cgtcgcctgc acgggatcgc cgctgaaaat aaaaccgcct
    12181 tcgtccaaaa tacggatcag ctcaaccagt tttcgggatg gattcaacat aaaatgccgt
    12241 ctgaaaataa aaaacagatt ttaacacacg cattttcaag aatattcaca gtgtaggcaa
    12301 agagtaaatc tcacacagaa gcaaaagtat cggcgtaaac tgactgcctc tactttcccg
    12361 aaagattgtg cgatgtatac aggcgaacgc ttcaatactt acagccattt gagcggtttg
    12421 attctggcgg cggcaggttt ggcgctgatg ctgctgaaaa ccataggaca cggggacggc
    12481 taccgtatct tcagcgtatc ggtttacggc atcagccttc ttctgctcta tttgagttcc
    12541 tcgctgtacc acggaattgc agccggaaaa ctgaaaagca ttttgaaaaa aaccgaccac
    12601 tgcatgattt atgtcctgat tgccggaagc tacacaccgt ttgcactggt ttctttgaga
    12661 aacgggccgg gctggacggt attttcactg tcctggctgc tggcggctgc aggaatcgca
    12721 caagaactca ccatcggacg gaaaagcgaa aaacgactgc tgtctattgc gatttatgtc
    12781 gtcatgggtt ggatggtctt ggcggtaatg aaatccctga cagcctcact cccgccggca
    12841 ggactggctt ggctggcggc aggcggtatg ctgtacagcg tcggcattta ctggtttgta
    12901 aacgatgaaa aaatccgaca cgggcacgga atctggcatc tgttcgtatt gggcggcagc
    12961 atcacccaat ttgtcagcgt gtacggttac gtaatctgaa tgccgtctga aaagcaaaac
    13021 ctcccgatcc tgaagattgg gaggttttct gtttgccgga catcagccct tgtcgtggaa
    13081 ctcgtgaaat tcatactgat aggacaaatc ccgacccgct tttttctgtg ccaaataatc
    13141 atcataaatg gcacggattt ccttacgcaa caaaaacagg gctatcaagt tcgggataac
    13201 cataaagccg ttgaacatat cggacaggct ccaaaccaaa tcgactttgc cgagcgtacc
    13261 caaaacgatg gcaagcagaa ccaatgcgcg atagatgccc aagtgtcttc ccctgaaaag
    13321 aaaacggatg ttggactcac cgaaataata ccagccgata atggtcgtca aggcgaaaaa
    13381 ggtcagacac acggcaagca attgcgaacc gaagcccgga aatgccttgt taaaggcaaa
    13441 ttgagtaacc gccgcgccct gttcgcccga aaggttggca tcggtcagca ggataatcag
    13501 cgcagttgcc gtacatacca aaatcgtatc gataaataca ccgacaaatg ccgccatacc
    13561 ttgctgcaca ggatgcttca catccgcagt cgcgtgggcg tgcggggtag aacccatccc
    13621 cgcttcgttg gaaaacagac cgcgcgccac gccgaaacgg acggcttcgc gcataccgat
    13681 acccgccgca ccgcccaaaa cggcttcggg attgaaggcg gcggtaaaga tgtggttgaa
    13741 catcggcaca atatggtcgg aaaattcaaa caggataacg acggcgcaca aaatataaac
    13801 aaccgccata aacggcacga caaattgggc gatattggca atacggttca cgccgccaat
    13861 cacaaccatg cccgcaagga cggcaagcac aataccgact gccaaagaag gcacatcaaa
    13921 tgcaatggta acggcagaag caatggagtt tgcctgtgtc gcattaccga taaagcccaa
    13981 tgcgataatc aacgcaatgg aaaagaaacc ggacaaaaaa cgcgccgcgc ccctgccgat
    14041 tttcggagtc agaccgtggg tgatgtagaa cgccggcccg ccgatgtatt tgccgtggct
    14101 gacgacgcgg tatttctgcg ccagcagtgc ctccgcaaaa atcgtggaca tccccaaaac
    14161 ggcagaaacc cacatccaaa aaatcgcgcc cggcccgcct gcggtgatgg cggtcgccac
    14221 gccggcgacg ttgcccgtac cgatttgcgc agatatggca accgccaacg cctgaaactg
    14281 cgataaagac ttgtcgtctt tatcgccttt ggcaaacaag ccgccgaata cggatttgaa
    14341 tcccgcgccc agcttggtaa tctgcggcgc accaagatac agcgtaaaaa acaggccgat
    14401 acccaaaagc gcgtaaatca gcaggtagtc ccaaaggaac cgattgactg tacccaccag
    14461 aacagacaat atattttcca taaaataaac cttatcttac aattaaaatg actgccttcc
    14521 aaaagacatt ccaataagga aacacggcga gcagaccgta tttgccgcaa cagatgcctt
    14581 aaattgtcaa caatcgggga gaagctgcgc catcataccg taaaatatcg ttaattaaaa
    14641 catttcttta tttttaagcg gaaagcggag gaaatcgctt tcagacggca tcgacaacgg
    14701 cacggcataa aacaggatat tttgggtact tgcaacttat gttaaaatgc cgaccgtaaa
    14761 aaatctgaca aaaacagatt aattatttga aataagaaag gaaatttatg gcaggccata
    14821 gcaagtgggc gaatatccag cataaaaaag cccgtcagga tgccaaacgc ggcaaaatct
    14881 tcacccgttt aatcaaagaa atcaccgttg cggcgcgtat gggcggcggc gaccccggtt
    14941 caaatccgcg cctgcgcctg gctttggaaa aagcagccga aaacaatatg cccaaagaca
    15001 atgtgcaacg cgccatcgac aaaggtacgg gcaacttgga aggcgtggaa tacatcgaat
    15061 tgcgctacga aggctacggc atcggcggcg cggctttgat ggtggactgc ctgaccgaca
    15121 acaaaacccg caccgttgcc gacgtgcgcc acgcgtttac caaaaacggc ggtaacttgg
    15181 gtactgacgg ctgcgtggcg ttcaacttcg tgcatcaggg ctatttggta ttcgaacccg
    15241 gcgttgacga agacgcgctg atggaagcgg ctttggaagc cggtgcggaa gacgtggtta
    15301 ccaacgacga cggttccatc gaagtcatta ccgcgccaaa cgattgggcg ggcgtaaaat
    15361 ccgctttgga ggcggcaggt tacaaatctg ttgacggcga cgttacgatg cgcgcccaaa
    15421 acgaaaccga actctccggc gacgatgccg tcaaaatgca aaaactgatt gacgcgctgg
    15481 aagacttgga cgacgtgcaa gacgtttaca cttccgccgt attgaatctg gactgatacg
    15541 cagcacagca gacatacaat aaaatgccgt ctgaaccttt cagatggcat tgatttattt
    15601 agcccttgcc cacgcccacc aaaccgtcag gacaaccgcc agaaaatacg ccgcgctcca
    15661 aacaggcaaa gcaaccccta acagataatc cggttcggca caatttccga acccgcgcac
    15721 gacaggctcg aaccaatcaa acaaagacca gcccttcaag cggaacgtcc acggcgcacc
    15781 gcacgaagga gccgtacccg gcggcagcga ctgcaaccac aactgatatg ccgcaacaga
    15841 aatacccgta acggccggaa tgctgataaa gacagcaccg aacaaaccgc ccgcccttct
    15901 tcttggtctg cacatcagga caattgccgt acacaatgcg gttgccaaaa cgcataaccg
    15961 ctgactgata cacaaaacgc aaggctccat acccaaaaca tactgtgccg ccaaagaacc
    16021 ggcaaatgca cagaccgaaa cggcaaacag cagccaaacg gcttttctaa ataacggggt
    16081 cattttctca acacaccaat caaaataccg atatgccgat tttgctggat atatcccgag
    16141 atggcaaggg acgaatcgac accggctcag gtgcggacga tttcggtttt ccccgatatg
    16201 cacaaaacct gacaagggac aaaacggcga tttgcccgca caatgcccac aaaaaaatac
    16261 atccggagga tttgaatttc agcaaattta gcgaatcaaa agtttatttc aatgaaatca
    16321 tatgattttt ttgaataagc ggattgatgg gtttttgaag gaatttgtta ccggatagcc
    16381 atcgggcaag ttttttgcaa aatttgaatc ggtcgggtaa attttcaaaa aataattgac
    16441 agcggataag aaacggcgga taattcccgc cgtcgagttg cttgatgcag cttgattttt
    16501 ctcctctatt tctcctttgt agacttggca cacattcaac cggatgtgtg cattttttta
    16561 tctccgcttt ttttgaaatt taattacttt tattgtttga aattccattc tttaagaaat
    16621 ttaacaagaa aaacgcttgc tttttgaccg gaaaagctgc ataattcgtt ccgttagctg
    16681 gttcgagtag tcagttaata gtttctcctc tatttctcct ttgtagactt ggcacacatt
    16741 ctattgaatg tgtgcatttt tttatctgaa gcaacaagcc tctgtgcgtg atgttgttat
    16801 gtttcattta ggtgtcaaac cgcatagcca gcctgaaata ttcaatccaa atccaaaacc
    16861 ggattttctt tgacctcctc catcacaaca taactcctac tctccgaagc ggcaggcagt
    16921 tgcaatagga tattgcctag catatcccga taggcagaca tatcgggcaa acgtacttta
    16981 atcagatagt cgtattcgcc cgacaccaag tggcattcca taatttgcgg aattttcagc
    17041 acttcttttt tgaaatcttc gaaaatattg cccgatttgg attgcagctt cagctcgaca
    17101 aaaaccaata gtggtttgcc caacagatgg ggattgagat gggcgtgata gccggaaata
    17161 taatgttccc gctccaaacg gcgcaccctc tctgtaacgg gcgtggtgga caagcctacc
    17221 ttctcggcaa gctccgtcat cgggatgcgg gcattctgtt ggaggatctt aagaatgcgg
    17281 aaatcgattt tatctagttc tttcatttgg attaccttgt atttattatt gattttaaca
    17341 aatagagtat atagtggatt aacaaaaacc agtacggcgt tgcctcgcct tgccgtacta
    17401 tttgtactgt ctgcggcttc gtcgccttgt cctgattttt gttaatccac tatatatttg
    17461 ggaaagcgat tatatcagga aaagcaaacc gccttcctac ctgaaaactg ctgcttcggc
    17521 ttgaagacac aagggtcttt aatattttaa aagccttgcc gttggattat aattccctaa
    17581 ttgatttctt aattttgcta ataaacactt gcttggtaag gaatgaattt atgcgccctt
    17641 tgaacgtgca gatcaggttg ggcaacctta ggcacaatta tcggatttta aaggaaatgc
    17701 acggaggcaa gctgttggcg gtagtgaagg ccgacgcata cggacacggt gcggtcagat
    17761 gtgctttcgc gctggcagac ttggcagacg gctttgccgt ggcgacaatc gatgaaggaa
    17821 tcaggctgcg ggagagcggc attacccatc cgattgtcct tttggaaggc gtatttgaag
    17881 catcagagta cgaagcggtc gaacaatact cgctctggcc ggcagtcgga aaccaatggc
    17941 aacttgaggc tttgctttcc cgccattgga aaaaacctgt caaggtctgg ttgaaaatgg
    18001 attcgggaat gcaccgtacc ggatttttcc ctcatgatta cgcttcggca tatgcggcat
    18061 tgaaacagtc ggaatatgtg gacagtattg tcaaattctc gcatttctcc tgtgcggacg
    18121 aacccgaaag cggtatgacg gaaatacaga tggaagcatt cgatttgggt acggaagggc
    18181 tggaaggcga agaaagcctt gccaattcgg cggctatttt gaatgttccc gaagcacgca
    18241 gggattgggg gcgcgcgggc ttggcgttat acggcatttc cccgttcgga ggcagcgatg
    18301 acaggctgaa acccgtgatg aggctttcaa cccgtatttt tggcgaacgc gttttacagc
    18361 cgcactcccc tatcggttat ggcgcaacat tttataccag caaatctacg cgcgtcggtc
    18421 tgattgcctg cggttatgcg gacggttatc cgcgccgcgc tccaagcaat tcccccgtcg
    18481 ccgtcgacgg taaattgacc cgggtcatcg gcagggtctc tatggatatg atgaccatcg
    18541 agctggacgc ttcgcaagaa ggtttgggac acgaggtcga actgtggggc gatacggtca
    18601 acatcaatac tgttgccgaa gcggccggaa ccatccctta cgaattgatg tgcaatatca
    18661 aacgtgcaaa attcacttat atcgagtaat cgagtccaaa caaaaatgcc gtctgaagcc
    18721 tttcagacgg catttcccca tcaaaaccgc aatcagtttt tcattgattg aaccggagcc
    18781 gggattctgc cgccccgttt gacgaacact tcgcacgaac cttctttgac cggcattaca
    18841 ggcgcgtagc ctaacaggcc gccgaactcg acactgtcgc cgacggtttt accggttacc
    18901 ggaataatgc gcacggcagt ggttttgctg ttgatcatgc cgatggcggc ttcgtcggca
    18961 atgatgccgg aaatggtgtg cgcgggtgtg tcgccgggaa cggcaatcat atccaagccg
    19021 accgaacaaa cggcggtcat cgcttcgagt ttatccaacg tcagcacgcc tgcttcggcg
    19081 gcggcaatca taccttcgtc ttcggaaacg gggataaacg cgccactcaa accgccaacc
    19141 gcgctcgaag ccatcatgcc gccctttttc acggcatcgt tcagcaatgc caaagctgct
    19201 gttgtgccgt gcgtaccgca gacgctcaaa cccatttctt caagaatgcg cgccaccgag
    19261 tcgccgacgg caggggtcgg tgccagcgac aagtcgagaa taccaaacgg gatattcagc
    19321 atttttgagg cttcgcggcc gatgagttcg cccacgcggg taattttgaa ggcggttttc
    19381 ttcacaactt cggcaacttc ggtcaatgtc gttgcatccg aattttccaa cgcggctttt
    19441 acgacacctg ggccggatac gccgacatta atcacagcat ccgcttcgcc cgatccgtga
    19501 aacgcacccg ccataaacgg attgtcttcc accgcattgc agaacacgac gattttcgcg
    19561 cagccgaaac cttcgggcgt aatttcagcc gtgcgtttga tggtttcgcc tgccagcttg
    19621 accgcatcca tattgatacc ggcgcgcgta ctgccgacat tgatggagct gcacacgatg
    19681 tcggtggtct tcatcgcttc gggaatggaa cggattaaca cctcgtctga aggcgacatg
    19741 cctttttgca ccaacgcgga aaagccgccg ataaaggaca cgccgatggc tttggcagcc
    19801 ttatccaaag tttgcgccac gctgacatag gaatcggcat gggtagccgc cgcgatttgg
    19861 gcaatcggcg taacggaaat gcgctgattc acaatcggca cgccgtattt ggcagacaga
    19921 tattttgccg tcgccaccaa gtctttgccg accgtggtaa ttttgttgta aatgttttgg
    19981 ttcaacacat tgatatcgct gctgatgcag tcgtgcagat caatgccgat ggtaatggtg
    20041 cggacatcaa aattctggtc ggcaaccatt ttgacggttt ctaaaatttc gccggattgg
    20101 atactcatca cattcctccg actcaaatgc ggtgcatcgc ttggaagatt tcttcatttt
    20161 gcatacggat atcaagcgcg agttttttgc tctcttccgc aaacaaatcc aaaacctcct
    20221 gccgagattt ggggcatttc gaggtatcca ccaagataat catggtaaaa aaatcatcca
    20281 tcagctgttg gctgatattg aggatgttga ttcggttttc cgccaaaatt ttggaaacat
    20341 cgtacacgat gccgacgcgg tctttaccga tgacggtgat gactgaattg ttcacaggct
    20401 tactccttgc agatatccgt taaagtccga aattatacca ccgttggatt ttgaagaaat
    20461 attgtcaaca atatatacat acaaaatgcc gtctgaaact atttcagaca gcatcaagat
    20521 tcagggttcg attaaataac catccttatc ccactgggtt ttcctgacca acttgtcatc
    20581 ctgataaaca gcttcactct ttttagaacc atcttcatac cactctaaga ctactccatt
    20641 acgtttatga tgatggatag acagttccga gagtaatcga ccgctttcat cccatgtcag
    20701 aatcttggcc ggctcatcat tgaccataac catttccgtt ttgatattgc catcagcata
    20761 ccattgtttc catacgccgt ttgccttatt ttgtttaaac tggatttcgc tttccttgct
    20821 gccattacgg taatagcggt accccgtacc ttcactcaaa ccatttttat aaggcataac
    20881 cgcagatttt ttaccgttcg gataccagtt gacccactca ccgtccggct tacccttgct
    20941 gaagcccccc gccatttttt tctgaccatt aaaatgccac aaaatcaaca taccgttttg
    21001 cagggtaggc acaaaagatt tgatttgcgt tgaagcaacg atataaggtt cggaatattt
    21061 cttcatcgac ggataataaa aatcctgcgc gtacgcaata ccctccgcca cactatattg
    21121 cctgatataa gcggcagaag acatcgtcgc cgtcagtttc ccgttctgat taaaataaac
    21181 agaataggtc tgtgccgata aagaagccga aaaacccaac aggacaattg aaaatacaat
    21241 ccgagataat tttttcattg caatagcgat ataaaaacaa ggctgtgttt tagtaatctg
    21301 ttgatttcaa ttatttgcaa gggaaaagac aattattttc cggttaggaa taaacctatt
    21361 ctactgaata tattgaagcc aagtacgcct atcaacacta tattaaaaca ctgccaaaaa
    21421 caattaactt ataaacaata tggtaaggat ttctctgcca agcatcaaac ccgagacaac
    21481 gtatcgtaaa aatgccgtct gaaaacaaat cgtcttcaga cggcatttcc ccttcaactc
    21541 actcttcacc caataactgc tcgcgcgtca agaggaaaac aaaaccgtcg cccccgctgg
    21601 tttccaacca agtaaaaggc aactccggat acgctgcttc caatacatcc ctgttatgcc
    21661 cgatttccac cagcaataca cctttgggat tcagaaactt tgccgcattc agaagaatct
    21721 gcctggtggc atccaacccg tccgccccgc tgcccaatgc caattccggt tcgtgcaaat
    21781 actcttcagg caataactca accgattccg catccacata aggcggattg gaaacaatca
    21841 aatcataagt gccttccaat ccttcaaaca aatccgtatg aataagccgg atgcgttctt
    21901 ccaaaccata atcttcgaca ttaatccctg ccacttccaa agcatccaag ctcacatcaa
    21961 ccgcatcaat ttgggcatca ggataatgat gcgccatctg aatggcaagg caaccgcttc
    22021 cggtgcaaag atccaaagca ttatgcacca actcatcgta ttctatccaa ggacgaagtc
    22081 cgtcacccaa caattcataa ataaaagaac gaggtatgat tacgcgctca tccacataga
    22141 aatcaaactc tccctgccat gcctggtgtg tcaaataagc ggctggaatg tgttcgacag
    22201 cacgacgctc aataaccgtc agcacttcct ctttttcagc ttccaagagt tttgcatcaa
    22261 gatatggggc aagcatatcc aaaggcaaat tcaaagtatg cagaatcaaa taagctgctt
    22321 catcatgcgc attatccgtt ccatgaccaa aaaagagccc tgcctcatta aaacggctga
    22381 ctgcaaaacg taaaacatcg cggatagtcg tcaattcttg tgctgcctga ttaaacataa
    22441 tatgaaccat tctgcgtata gatactttta attataacag aaacaacaag caaacctttt
    22501 catatcgcca aataaccacc caatctaccc atacaactac ataaatgccc gcgcgaaaac
    22561 catcgcccga acggaaacga caatggccga cggtatgggc aacctgattg gctgggaaaa
    22621 aacggggctt gttgccggta agcagtggat aaccgcaaaa gacgacaagg tgtccgatgt
    22681 ctgcaatgcc aacggcgaga tgggcgtaat cgggctttac gagcctttct cacacggcgc
    22741 attgacgata cccggtcatc cgaactgccg atgcgaggtt gtttccgtat cgggtggcga
    22801 attgggggaa tttgccgaaa aaaaggagct tcgtaaagcg gctatgcagt atgcgcggga
    22861 taactttatc ggcaaaagct atgtcaatga aaacagcggg catgaactga aggtaacttg
    22921 gcaaggtgtg aaacacgctg cgtcaaaggc aaatcaggcg gaattatcca tcatgacaaa
    22981 acttgatgac ttattgcgct acgcaaaata tgagggttct tattcggata ggaaaggtca
    23041 tcctaatatt attgcagcac ataagtatcg tgccgttgcc aaggttggga atgagtcttt
    23101 aaatatcggt gtgattgtaa gggaatttcc agacgaccat aaacattacg accatttcat
    23161 cttgaaggat gaataaagcc cttttgcagt gtcgttctgg agcggatagc gttaaggcaa
    23221 gtacacttcc agccttgaaa aagggcttta aattcagcat gccatttata caggcaggag
    23281 taaacccatg acaaagttat acgcagaaat cgccaagatg gagacgcagg acgacgacac
    23341 ggtcaaggtt tggggttacg cttcaagcga ggaaatcgat tcggacggcg aagtcatcgc
    23401 gacggcagct atgaaggcgg cgattcccga ttatatgaag tttggcgagg ggcgcgagat
    23461 gcacggctca aacgctgcgg gaacggcaat tgaaatcaac gttgaagacg acggcataac
    23521 ctttttcggt gctcatatca tcgaccccgt tgtcgtggcg aaagtcaaaa caggcgttta
    23581 caaaggcttt tccatcggcg gcagcgttac cgcccgcgat gatttgaaca agtcccaaat
    23641 cacgggcttg aagctgacgg aaatcagcct tgtcgaccgc cctgccaatc ccgatgcggt
    23701 gtttacctgc tttaaggcgg acaaaggtgc ggaagcggta aacaacgata cagaacataa
    23761 tgctacatat tttagccatt tcccttccaa acaaaaaagc accggcggca gccgatgccc
    23821 cttcctttac aggttcccct attttttatc cgcgggcagc actggtttag ctgggccttt
    23881 tggtgcgggt gcgccgaccg aagcctgatc cttcagcttc gccagcaccg cagggccgat
    23941 gccctttacc ttggtcaaat cgtc
//
LOCUS       DAXIDM010000020        23867 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000020 DAXIDM010000000
VERSION     DAXIDM010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23867
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.020"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(67..906)
                     /locus_tag="ACFOAE_000663"
     CDS             complement(67..906)
                     /locus_tag="ACFOAE_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome"
                     /protein_id="HFC6884197.1"
                     /translation="MKQLRDNKAQGSALFTLVSGIVIVIAVLYFLIKLAGSGSFGDVD
                     ATTEAATQTRIQPVGQLTMGDGIPVGERQGEQIFGKICIQCHAADSNVPNAPKLEHNG
                     DWAPRIAQGFDTLFQHALNGFNAMPAKGGAADLTDQELKRAITYMANKSGGSFPNPDE
                     AAPADNAASGTASAPADGAAPAEAKAEDKGAAAPAVGVDGKKVFEATCQVCHGGSIPG
                     IPGIGKKDDWAPRIKKGKETLHKHALEGFNAMPAKGGNAGLSDDEVKAAVDYMANQSG
                     AKF"
     gene            1191..1266
                     /locus_tag="ACFOAE_000664"
     tRNA            1191..1266
                     /locus_tag="ACFOAE_000664"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1224..1226,aa:Arg,seq:ccg)
     gene            complement(1331..2524)
                     /locus_tag="ACFOAE_000665"
     CDS             complement(1331..2524)
                     /locus_tag="ACFOAE_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HFC6884198.1"
                     /translation="MYRHIEYYPGDPILSLVETFKNDPRPEKVNLSIGIYFDDEGKMP
                     VLESVSRAETARAAAPAPSPYLPMEGLDTYRSAVQHLLFGKDNPALAQGRIVTVQTLG
                     GSGALKVGADFLHRWFPEARAYVSDPTWDNHRGIFEGAGFEVGTYPYYDPATVGVKFD
                     EMTAFFNTLPENSVLILHPCCHNPTGVDMSEQQWDEVLHIIKRRKLIPFMDIAYQGFG
                     GDLDSDAYAVRKAVEMELPLFVSNSFSKNLSLYGERVGGLSVVCPNKEEADLVFGQLK
                     FTVRRIYSSPPAHGAYIAADAMNSPELYALWQNEVYMMRDRIRAMRQKLYDVLTAQIP
                     DRDFTYFIKQRGMFGYTGLSVEQVRRLRDEFAVYLLDSGRMCVAGLNTSNTDYVARAF
                     AEVLK"
     gene            complement(2545..3633)
                     /gene="trmA"
                     /locus_tag="ACFOAE_000666"
     CDS             complement(2545..3633)
                     /gene="trmA"
                     /locus_tag="ACFOAE_000666"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030697 - tRNA
                     (uracil(54)-C5)-methyltransferase activity, S-adenosyl
                     methionine-dependent [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HFC6884199.1"
                     /translation="MSDYTQQLQDKKDHLKTLFAGLDVPEWEVYESPDKHYRMRAEFR
                     IWHEGGEMFYAMFEKGQKAGGASLIRCDRFEAASEAVNRLMPELIALAAQSAELRNRW
                     YAVEFLSTLGGEMLVTMIYHKRLDDEWMQAAQALQQQLDISVIGRSRGQKIVLKQDYV
                     TETLKVGNRDFRYRQIEGSFTQPNAAVCQKMLEWACGAAEGLDGDLLELYCGNGNFTL
                     PLSEKFERVLATEISKTSVSAAQWNIEANRIGNIKIARLSAEEFTEAYTGKREFKRLK
                     DGGIALTDYAFSTIFVDPPRAGIDEETLKLVSQFDNIIYISCNPETLRANLDTLAETH
                     AVERAALFDQFPFTHHIESGVLLKKKIL"
     gene            3776..4876
                     /gene="aroC"
                     /locus_tag="ACFOAE_000667"
     CDS             3776..4876
                     /gene="aroC"
                     /locus_tag="ACFOAE_000667"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFC6884200.1"
                     /translation="MAGNTFGQLFTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFD
                     LDRRKPGTSRHVTQRREADQVEILSGVFEGKTTGTPIALLIRNTDQRSKDYGNIATSF
                     RPGHADYTYWHKYGTRDYRGGGRSSARETAARVAAGAVAKKWLKEKFGTEITAYVTQV
                     GEKKIRFEGCEHISQNPFFAANQSQIAELENYMDSVRKSLDSVGAKLHIEAANVPVGL
                     GEPVFDRLDAEIAYAMMGINAVKGVEIGAGFGSVVQRGSEHGDELTPQGFLSNHSGGI
                     LGGISTGQDIRVNIAIKPTSSIATPRRSIDINGNPIELATHGRHDPCVGLRAAPIAEA
                     MLALVLIDHALRHRAQNADVQVNTPDITLSNK"
     gene            4968..5393
                     /locus_tag="ACFOAE_000668"
     CDS             4968..5393
                     /locus_tag="ACFOAE_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FINO family protein"
                     /protein_id="HFC6884201.1"
                     /translation="MTQETALGAALKSAVQTMSKKKQTEMIADHIYGKYDVFKRFKPL
                     ALGIDQDLIAALPQYDSALIARVLANHCRRPRYLKALARGGKRFDLNNRFKGEVTPEE
                     QAIAQNHPFVQQALQQQSAQAAAETPSVEAEAAGSSAAE"
     gene            complement(5467..7452)
                     /gene="parE"
                     /locus_tag="ACFOAE_000669"
     CDS             complement(5467..7452)
                     /gene="parE"
                     /locus_tag="ACFOAE_000669"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFC6884202.1"
                     /translation="MAKNNQYSESSITVLKGLEPVKERPGMYTRTDSPTHICQEVIDN
                     AADEALGGFATAIDVQIHEDGSLSVRDNGRGIPVGLHPEEGVSVVELVFTRLHAGGKF
                     NKKDGGSAYAFSGGLHGVGVSVTNALSTRLEVTVKREGKIHRIVFAGGDVVEPLAQVG
                     KCAVKDSGTEVRVWPDGKYFESPNYSIPELERLLRAKAVLLPGVRVSLTRPVKGEDEA
                     RTQTWHYPDGLKSYLTDLIADAQEAVPLFSCENYISDDHNGDFSIGEGAAFALTWLEE
                     GSCANESYVNLIPTPLGGTHEAGLKQAVFNAVNNFINLHNLLPRGVKVQSDDVFGKTA
                     FVLSARVLDPQFQGQTKDKLTNRDALKLVAAVSGDPLELWLNQNVDFGKKIAELAIRQ
                     AQARMRSVKKIEKKKGSGVAVLPGKLTDCESEDIRENELFLVEGDSAGGSAKLARDKA
                     TQAILPLRGKVLNSFEVHPDQLFGNAEIHDISVAIGVDPHGINDHPDLSGLRYGKIAI
                     LSDADVDGSHIQVLLLTLFYRHFPKLVADGHIYVAQPPLFRVDVNAQGKNKPARKFYA
                     LDQNELDSILERLQKEGFKETAYSISRFKGLGEMNPDQLKDTTMHPDTRRLLQVQIPE
                     GADDETRDIFVKLMGKGEAAARRAWMEREGDTAELDI"
     gene            complement(7519..8067)
                     /locus_tag="ACFOAE_000670"
     CDS             complement(7519..8067)
                     /locus_tag="ACFOAE_000670"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HFC6884203.1"
                     /translation="MNLTEGDTVLDREGYRPNVGIILINERNEVFWGKRVREHSWQFP
                     QGGIKPGESPETAMYRELYEEVGLLPQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRG
                     QKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIEFKRDVYLGALKELS
                     SRFLRGMESYEDFAARQPSGNR"
     gene            8208..9503
                     /gene="serS"
                     /locus_tag="ACFOAE_000671"
     CDS             8208..9503
                     /gene="serS"
                     /locus_tag="ACFOAE_000671"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFC6884204.1"
                     /translation="MLDIQLLRSNTAAVAERLAARGYEFDAARFNALEEQRKAVQVKT
                     EELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQIKTDLEQAAADLDAVQKELDAWL
                     LSIPNLPHESVPAGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSG
                     ARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDL
                     FHVTRGGDETKTTQYLIPTAEVTLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGK
                     DTRGLIRQHQFDKVEMVQIVHPEKSYETLEEMVGHAENILKALELPYRVITLCTGDMG
                     FGAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGL
                     AVGRTLVAVLENHQNADGSINIPAALQPYMGGVAKLEVK"
     gene            complement(9576..10574)
                     /locus_tag="ACFOAE_000672"
     CDS             complement(9576..10574)
                     /locus_tag="ACFOAE_000672"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008720 - D-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_function: GO:0070404 - NADH binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFC6884205.1"
                     /translation="MKIAIYGTKSYDREHFTRANRHFGFELEFFDFMLDAKTAKMAEG
                     AEAVCIFVNDDGSRPVLEKLAQIGVKTVALRCAGFNNVDLKAAEELGLKVVRVPAYSP
                     ESVAEHTVGLMLTLNRRIHKAYQRTRDANFSLEGLTGFNMYGKTAGVIGTGKIGIATM
                     RILKGFGMNLLAYDPFCNPEVEKLGGKYVDLDELYAQSDIITLHCPSTPENHYMLNEA
                     AFDKMKDGVMIINTSRGGLIDSAAAIEALKRRKIGALGMDVYENERELFFEDKSNDVI
                     TDDVFRRLSSCHNVLFTGHQAFLTEEALGNISEVTLSNIREVGQTGDCGNAVRADG"
     gene            complement(10699..11775)
                     /gene="prfA"
                     /locus_tag="ACFOAE_000673"
     CDS             complement(10699..11775)
                     /gene="prfA"
                     /locus_tag="ACFOAE_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003790927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFC6884206.1"
                     /translation="MKPSILEKLQQLGDRLEEVTHLLGQPEATSDMDNYRKLTREHAE
                     LTPVVEVFQNYRLAQSDLADAEEMLSDPEMKDFAAEEIEAAKAKIGALDTELQKLLLP
                     KDADDDKNIFIEVRAGTGGDEAALFASDLLRMYSRYAERNRWQVEIVSANESELGGYK
                     EVIARIIGLGAYSRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEADELEDIELN
                     PADLRIDTFRASGAGGQHINKTDSAVRITHLPTGMVVECQDGRSQHANKAQAMKVLAA
                     RLNDAQKREAQAKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLHKLDFVMD
                     GDLAEITDALIAEHQAELLAAMGD"
     gene            complement(11866..12636)
                     /locus_tag="ACFOAE_000674"
     CDS             complement(11866..12636)
                     /locus_tag="ACFOAE_000674"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFC6884207.1"
                     /translation="MNFTDTHCHLADAALRENLPHILTAARKVGVKRFIVPATCPQDW
                     QSVAELSEMPSEHGQIRIALGIHPWFSDGIAERDCVRLEAMLARYPQAWVGEIGLDFY
                     DKTQTPPQRERQIQVFVRQLAIAQTLRRRVIIHNLKATADIAAAVKQTGFAQGGIVHA
                     FSGSAEEARVLTKLGFKIGIGSLLLNPNARKVRDTLKALNDGDFVLETDSPFMLKNTV
                     NTPANILRIAEIAAQIRGTGAAEIAAITERNADSLLRP"
     gene            complement(12751..13740)
                     /locus_tag="ACFOAE_000675"
     CDS             complement(12751..13740)
                     /locus_tag="ACFOAE_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFC6884208.1"
                     /translation="MKQKIFVLYTGGTIGMTQSSEGLRPDTALVGQALAPFSNGMDFD
                     WHVCGPLIDSSAVQLQNWCAWLDIIAAALPQYDGVLVLHGTDTLAYTANLFALALQGL
                     DKPIVLTGSQWPYNAVGSDAPRNLATAVAAFPLGLKQTLIAFDGKLYPAVGSSKVSTE
                     TAAGFDNPHFGALAEWDETRGWHNVRIPNQDAADVSDGLKIRYPDPQAKIAVRTLIPG
                     FAVQELADGLGQFPAQALILQSYGHGNTPADEGFIRAVRDFARQGKLLLNISQVRQGR
                     TAAVYAQGNAFRNSGIINGGKCNLETATALMTLAVSQGWGKEEVEKELARLKL"
     gene            complement(13807..14490)
                     /locus_tag="ACFOAE_000676"
     CDS             complement(13807..14490)
                     /locus_tag="ACFOAE_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFC6884209.1"
                     /translation="MFALLEAFFVEYGYAAVFFVLVICGFGVPIPEDLTLVTGGVISG
                     MGYTNPHIMFAVGMLGVLVGDGIMFAAGRIWGQKILKFKPIARIMTPKRYAQVQEKFD
                     KYGNWVLFVARFLPGLRTAVFVTAGISRKVSYLRFLIMDGLAALISVPVWIYLGEYGA
                     HNIDWLMAKMHSLQSGIFIALGVLAAALAWFWWRKRRHYQLYRAQLSEKRAKRKAEKA
                     AKKAAQKQQ"
     gene            complement(14679..16013)
                     /gene="glmM"
                     /locus_tag="ACFOAE_000677"
     CDS             complement(14679..16013)
                     /gene="glmM"
                     /locus_tag="ACFOAE_000677"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFC6884210.1"
                     /translation="MAKKYFGTDGVRGEVGQFPITPDFVLKLGYAAGQVLVQHDTDQK
                     PTVLIGKDTRISGYMLEAALVAGFTAAGVNVVQTGPLPTPGVAYLTRALRLSAGVMIS
                     ASHNAYSDNGIKFFAEGGVKLSDEIELEIEAKIDEEMKTQPSARLGRARRISGADDRY
                     IEFCKSTFPSHSDLRGLKLVIDTANGAGYGVAPKVFHELGAQVVSIGDEPNGYNINEK
                     CGATYTKTLQAAVLQHEADYGIALDGDGDRLMMVDKNGKVYDGDSLIYVIAKARAREG
                     INIGGVVGTVMTNMAMEIALKEQGVDFCRAKVGDRYVLEQLNQRGWLIGGEASGHILC
                     MDKHNTGDGIISALQVLAALQTLNQDLATVCADWQPYPQTMINVRIQKGQKWQEASKD
                     VLAEVEKELEGKGRVVLRASGTEPVVRVMVEARQADWARDGAERIAAAIGGI"
     gene            complement(16143..16994)
                     /gene="folP"
                     /locus_tag="ACFOAE_000678"
     CDS             complement(16143..16994)
                     /gene="folP"
                     /locus_tag="ACFOAE_000678"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HFC6884211.1"
                     /translation="MARHVWQAGRFEIGLDKPKIMGIVNLTPDSLSDGGAYSQNAKTA
                     LAHAERLLKEGADILDIGGESTRPGADYVSPEEEWARVAPVLAEVAGWGVPVSLDTRH
                     TAVMEKALALGGIDIINDVAALTDEGALELLARQTDTGICLMHMQGLPKNMQINPKYQ
                     DVVGEVTRYLKARAAECIAAGIAPQRITLDPGFGFGKTLQHNIALMRHLPELMAETGL
                     PLLIGVSRKSMIGELTGETDAAARVHGSVAAALASVARGAQIVRVHDVKATADALKVW
                     EALGINL"
     gene            complement(17134..18027)
                     /locus_tag="ACFOAE_000679"
     CDS             complement(17134..18027)
                     /locus_tag="ACFOAE_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFC6884212.1"
                     /translation="MIIVMSRRAAEADIAGVVAFIRSRGLREHISHGDERTVIGAIGD
                     DRVLSVREVQTLPEVEKAVRILDTWKTVSRENRAEDSRVAAKGVAFGGGETVRIAAEP
                     SVWRNADAVFLDPFFTSANLYDTSSADEGRGRCRRLAEQTASAHGAGKPVLVRVRNVR
                     HVEAALNAGADILYLGGGLMSDLAVLNEAGNLNIPLVLCKDKHHSAEDWLNAAEYVVS
                     RGNRHLILGESGVLSHTKDHPYRLDVESIVKVRQISHLPVIANITGLWNRDMPQEILY
                     GLAKAAGACGIVGTCFEKSGG"
     gene            18118..20232
                     /locus_tag="ACFOAE_000680"
     CDS             18118..20232
                     /locus_tag="ACFOAE_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HFC6884213.1"
                     /translation="MDLLSVFHKYRLKYAVAVLTILLLAAVGLHASVYRTFTPENIRS
                     RLQQSIAHTHRKISFDADIQRRLLPRPTVILKNLTITEPGGDQTAVSVQETKIGLSWK
                     NLWSDQIQIEKWVVSSAELALTRDGKGVWNIQDLIDSQKRQASVNRIIVENSTVRLNF
                     LQEQLILKEINLNLQSPDSSGQPFESSGILVWGKLSVPWKSRGLFLSDGIGTPEISPF
                     HFEASTSLDGHGITISTTGTPAIRFNAGGADAAGLGLRADTSFRNLHLTAQIPALALR
                     NNSIKIETVNGAFTAGGEYARWDGSFKLDKANLHSGIANIGNAEISGSFKTPRHQTNF
                     SLNSPLVWTENKGLDAPRLYVSTLQDTVNRLPQPRFISRLDGSLSVPNLQNWNAELNG
                     TFDRQTVAAKFRYTHEDAPHLEAAVALQKLNLTPYLDDVRQQNGKIFPDTLAKLSGDI
                     EAHLKIGKVQLPGLQLDDMETYLHADKGHIALSRFKSGLYGGHTEGGISIANTRPATY
                     RLQQNASNIQIQPLLQDLFGFHSFSGNGDAVIDLTAGGETRKELIRSLQGSLSLNISN
                     GAWHGIDMDNILKNGISGKTADNAAPSTPFHRFTLNSEISDGISRHIDTELFSDSLYV
                     TSNGYTNLDTQELSEDVLIRNAVHPKNKPIPLKITGTVDKPSITVDYGRLTGGINSRK
                     EKQKILEDTLLEQWQWLKPKEP"
     gene            complement(20296..21774)
                     /gene="ubiD"
                     /locus_tag="ACFOAE_000681"
     CDS             complement(20296..21774)
                     /gene="ubiD"
                     /locus_tag="ACFOAE_000681"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HFC6884214.1"
                     /translation="MKYKDLRDFIAMLEQQGKLKRIAHPVSPHLEMTEIADRVLRAEG
                     SALLFENPIKPDGTRYGYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEP
                     PKGIKDAFSKLPLLKDIWSMAPNVVKNAPCQEIVWEGEDVDLYKLPIQHCWPEDVAPL
                     VTWGLTVTRGPHKKRQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEFRKLNPDTPYP
                     VAVVLGCDPATILGAVTPVPDTLSEYQFAGLLRGSRTELVKCIGNDLQVPARAEIVLE
                     GVIHPNETALEGPYGDHTGYYNEQDHFPVFTVERITMRENPIYHSTYTGKPPDEPAVL
                     GVALNEVFVPLLQKQFPEITDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMMGCWSFLR
                     QFMYTKFIIVVDDDVNVRDWKEVIWAVTTRMDPVRDTVLVENTPIDYLDFASPVSGLG
                     GKMGLDATNKWPGETDREWGRVIKKDPAVTAKIDGIWEELGL"
     gene            complement(21794..22309)
                     /locus_tag="ACFOAE_000682"
     CDS             complement(21794..22309)
                     /locus_tag="ACFOAE_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2199 domain-containing protein"
                     /protein_id="HFC6884215.1"
                     /translation="MYTCTSCGEKHEDMPAIGFTAPYPYNQLSEEERIAYQAECDSDF
                     CIIRYPVQTDRFIRAVLPIPIIGHQETLEYGVWVSVSEKSFNDYQSHFHDNPENVVYF
                     GMICNRLPPYESDTFGLHCNVVTQPDGQRPLLQLHQSGGHPLVRDFYHGIEYAEAQAR
                     IGAVSESDCSG"
     gene            complement(22316..22750)
                     /locus_tag="ACFOAE_000683"
     CDS             complement(22316..22750)
                     /locus_tag="ACFOAE_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009424955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884216.1"
                     /translation="MCGLWLLRALTAKLPQQRYAALFITLFFAAVLVFGRHDSMYWYP
                     VLVNLMMLAVFGGSLFAGQTVIERLARPQQPDLPEKAVRYTRRVTQVWCVFFIANGTL
                     AALLVRLGRYDWWAVYTGVIAYVLMGMPFAGEWLYRKLVLKV"
     gene            complement(23032..23115)
                     /locus_tag="ACFOAE_000684"
                     /pseudo
     CDS             complement(23032..23115)
                     /locus_tag="ACFOAE_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222119.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
     gene            complement(23118..23618)
                     /locus_tag="ACFOAE_000685"
                     /pseudo
     CDS             complement(23118..23618)
                     /locus_tag="ACFOAE_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714696.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl synthase chain length factor"
     gene            23674..>23867
                     /locus_tag="ACFOAE_000686"
     CDS             23674..>23867
                     /locus_tag="ACFOAE_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6884217.1"
                     /translation="MKITHCKLKKKVQKELIRFFVLEVTARSAADILGIHPNSAALFY
                     RKIRTVINHHLALAADEVFE"
BASE COUNT         5399 a         6796 c         6255 g         5417 t
ORIGIN      
        1 attcccataa aaaaacggag cagatacctg ccccgttttt atttaatccg aaattttaat
       61 ctaaatttag aattttgcac cggattggtt tgccatatag tcaacagccg ctttgacttc
      121 gtcatcgctc aaacctgcat tgccgccttt ggcaggcatc gcgttaaagc cttcaagggc
      181 gtgtttgtgc aaggtttctt tgcctttttt gatacgcggt gcccaatcgt cttttttgcc
      241 tatgccggga ataccgggaa tcgaaccgcc gtggcacacc tgacaggttg cttcgaagac
      301 ttttttaccg tcaacgccga ccgcaggggc tgccgcaccc ttgtcttctg ccttcgcttc
      361 tgccggagct gcaccatcgg caggagcaga agctgttcct gaagcggcat tgtcggcagg
      421 cgcagcctca tcaggattcg ggaaagaacc gccgcttttg ttcgccatgt aagtaatcgc
      481 ccgtttgagt tcctgatcgg tcaggtctgc cgcaccgcct ttggcaggca tggcgttaaa
      541 gccgttcagc gcgtgttgga acaaggtatc gaagccttgc gcgatacgcg gtgcccaatc
      601 gccgttgtgt tccagtttcg gagcgttcgg cacattgctg tccgccgcgt ggcattggat
      661 acagattttg ccgaaaatct gttcgccttg gcgttcgccg acggggatgc cgtcgcccat
      721 cgtcaattgt ccgacgggct ggatacgggt ctgcgttgct gcttccgtag tggcatcgac
      781 atcgccgaac gagccgctgc ccgccagctt aatcaggaaa taaaggactg caataacaat
      841 aacgataccg ctcacaaggg taaacagtgc agagccttgg gctttattgt cgcggagttg
      901 tttcatttgg taggcctcgc cgtcaggtta ggttgtgctg taaattatag tttggtgtgt
      961 taaacgcagt taacaatatt ttgctggatt atactgaatt cacagggtct ttccaatcgc
     1021 tatcattgaa aatatgaaaa aatttgccaa cggtatctgt ataaaacaaa taatcctttg
     1081 aaaataattg tttatcctca agaaaactct ccttatgccg ccatacgccg cctgccggcg
     1141 caagataacc tttgccaatt tgcagaattt acgttaacct tacgttttcc gcacccatag
     1201 ctcagttgga agagtgtcag tttccgaagc tggaggtcac aggttcgatc cctgttgggt
     1261 gcgccaatta taaagaggcc gtctgaaaga taaatatttt tcagacggtc ttttgactta
     1321 cttcaaactc ttatttcaag acttccgcaa atgcgcgggc aacatagtcg gtattcgacg
     1381 tattcagtcc ggcgacgcac atcctgccgg aatccagcag gtaaacggca aattcgtcgc
     1441 gcagcctgcg gacttgttcc acgctcaatc ctgtgtagcc gaacatgccg cgctgtttga
     1501 tgaaataagt gaaatcgcga tcggggattt gcgcagttaa gacatcataa agtttctgcc
     1561 gcatcgcacg gatgcggtcg cgcatcatat aaacctcgtt ttgccacaag gcgtaaagtt
     1621 cggggctgtt catcgcgtcg gcggcgatat acgcgccgtg cgcgggcggg ctggagtaga
     1681 tgcggcggac ggtgaatttg agctgtccga acaccaaatc cgcttcttcc ttattcgggc
     1741 aaaccacgct taagccgccg acgcgctcgc cgtagagcga caggtttttt gagaaggaat
     1801 tgctgacgaa caagggcaat tccatttcca ccgctttgcg gacggcgtag gcatcgctgt
     1861 ccaaatcgcc gccgaatcct tggtaggcaa tgtccataaa cggaatcagt ttgcgccttt
     1921 tgatgatgtg caacacttcg tcccattgtt gttccgacat atccacgccg gtcgggttgt
     1981 ggcagcaggg atggaggatc aggacgctgt tttcgggcag ggtgttgaaa aacgcggtca
     2041 tttcgtcgaa tttcacgccg acagtggcag ggtcgtaata tgggtaagtg ccgacctcga
     2101 aacctgcgcc ttcaaaaatg ccgcgatggt tgtcccaagt cgggtcgctg acgtaggcgc
     2161 gcgcttcggg aaaccagcgg tgcaggaagt ccgccccgac tttgagcgcg cccgagccgc
     2221 ccaaggtttg tacggtaacg atgcgccctt gcgcaagcgc gggattgtct ttgccgaaca
     2281 ataaatgctg caccgcgctg cggtaagtgt ccaagccttc catcggcagg tagggcgacg
     2341 gcgcaggcgc ggcggcacgg gcggtttcgg ctcggctcac ggattccaac acgggcattt
     2401 tgccttcgtc gtcgaaataa atgcctatgc tcaaattgac tttttcgggg cgcgggtcgt
     2461 ttttgaaggt ttcgaccaaa ctcaaaatcg ggtcgccagg atagtattcg atgtgtcggt
     2521 acatagtcct tacctcttgc tttttcaaag gattttcttt ttcaacaata caccactttc
     2581 gatatggtgc gtaaacggga attggtcgaa cagggcggca cgttcgaccg catgggtttc
     2641 cgccaaggtg tccaaattgg cgcgcagcgt ttcgggattg caggaaatgt agatgatgtt
     2701 gtcaaactgc gacaccagct tcaaagtttc ctcatcgata ccggcacgcg gcggatcgac
     2761 gaaaatagtg gaaaatgcgt aatccgtcaa agcaatacca ccatccttaa ggcgtttaaa
     2821 ctcacgtttg ccggtatagg cttcggtaaa ttcttcggca gacagacggg cgattttgat
     2881 gttgccgatg cggttggctt cgatattcca ttgcgccgcg ctgacggagg ttttggagat
     2941 ttcggttgcc aaaacacgtt caaacttttc agataaagga agcgtaaagt tgccgtttcc
     3001 gcaatacagt tcgagcaaat ccccatccaa tccttctgct gcaccgcagg cccattcaag
     3061 cattttctga cacacggcgg cattcggttg ggtaaaactg ccttcaattt gccgataacg
     3121 gaaatcccgg ttgccgacct tcaaagtttc cgttacatag tcctgtttta agactatttt
     3181 ctgtcccctg ctccgcccaa taacggaaat atccaactgt tgctgtaacg cttgcgccgc
     3241 ctgcatccac tcatcatcaa gccttttgtg gtaaatcata gtaaccagca tttctccgcc
     3301 gagcgtagac agaaattcga cggcatacca acggtttctc agttcggcag attgggcggc
     3361 aagggcgatc aattcgggca tcaggcggtt gacggcttcg gaagccgctt caaaacggtc
     3421 gcaacggatc aggcttgccc cgccggcctt ctgccctttt tcaaacatag cgtaaaacat
     3481 ttcaccgcct tcgtgccaaa tacggaactc ggcacgcata cggtaatgtt tgtccggaga
     3541 ttcgtacacc tcccactcgg gaacatccaa acctgcaaaa agggttttaa ggtggtcttt
     3601 tttatcttga agctgctgcg tgtagtcgct catatcgcta tcctgaaaaa tcagaccgga
     3661 ttataagccg attcactgca aaacacgcaa cccctttacc ggcatataac ccgttttcct
     3721 ccgactttta tgctaaaatc cgccgtctcc aacataccgc cgacagaagg aaaatatggc
     3781 aggcaacact ttcggacaac tcttcaccgt taccactttc ggcgaaagcc acggcgcggg
     3841 tttgggctgt atcatcgacg gctgcccgcc cggcttggaa ttaagcgaag cggatatcca
     3901 atttgacctt gaccgacgca aacccggcac cagccgccac gttacccaac gccgcgaagc
     3961 cgaccaagtc gaaatcctct ccggcgtatt cgaaggcaaa accactggca cgcccatcgc
     4021 cctcttaatc cgcaataccg accagcgcag caaagactac ggcaacatcg ccaccagctt
     4081 ccgccccggc cacgccgact atacctattg gcacaaatac ggcacgcgcg actaccgggg
     4141 cggcggtagg agttccgccc gcgaaaccgc cgcccgcgtt gctgccggag ccgttgccaa
     4201 aaaatggttg aaagaaaaat tcggcacgga aatcaccgcc tacgttaccc aagtcggcga
     4261 aaaaaaaatc cggtttgaag gctgcgaaca catttcccaa aatccttttt ttgccgccaa
     4321 ccaaagccaa attgccgagc tggaaaacta tatggacagt gtgcgcaaat cgttggattc
     4381 cgtcggagcg aagctgcata ttgaagccgc caacgtcccc gtcggcttgg gcgaacccgt
     4441 attcgaccgc ctcgatgccg aaatcgccta cgcgatgatg ggcatcaacg ccgtcaaagg
     4501 cgtggaaatc ggcgcaggtt ttggcagcgt tgtccaacgc ggcagcgaac acggcgacga
     4561 actgaccccg caaggcttcc tgtccaacca ctcaggcggc atcctcggcg gcatcagcac
     4621 cgggcaagac atccgcgtca atatcgccat caaacccacc agctccatcg ccaccccgcg
     4681 ccgcagtatc gacatcaacg gcaaccccat cgaactcgcc acgcacggca ggcacgaccc
     4741 ctgcgtcggc ttgcgcgccg cgccgattgc agaagctatg ctggcattgg ttttaatcga
     4801 ccacgccctg cgccatcgcg cgcaaaatgc ggatgttcag gttaatacgc ccgacattac
     4861 cctttcaaac aaataaaaat ttagccaaaa cacagacttt ataatagaat accgagcatt
     4921 gccgtgccgc tttgacgcac gggtttgttt agaggaatac aaccgaaatg acacaagaaa
     4981 ccgctttggg cgcggcactg aaatccgccg tccaaactat gagcaaaaag aaacagaccg
     5041 aaatgatcgc cgaccacatc tacggcaaat acgatgtatt caaacgcttc aaaccgttgg
     5101 cgctcggcat tgatcaggat ttgattgccg ctttgccgca atacgattcc gcactgattg
     5161 cacgcgtcct cgccaaccac tgccgccgtc cgcgttatct gaaagccttg gcgcgcggcg
     5221 gcaaacgttt cgatttgaac aaccgtttca aaggcgaagt tacccccgaa gaacaggcga
     5281 tcgcgcaaaa ccatcctttc gtgcagcagg ctttgcaaca gcagtccgcc caagctgccg
     5341 ccgaaacgcc gtctgttgaa gccgaagcag ccggatcttc cgcagcagaa taaatcccca
     5401 aacgaaatgc cgtctgaaaa ccgatttggt ttcagacggc attttttcgt atgcggcaat
     5461 cacggttcaa atatccaatt ccgccgtatc gccttcgcgt tccatccaag cgcggcgggc
     5521 ggcggcttcg cctttgccca tcagtttgac gaagatgtcg cgtgtttcgt catctgcgcc
     5581 ttctgggatt tgtacctgca acagacggcg ggtgtcgggg tgcatggtgg tgtctttgag
     5641 ttggtcgggg ttcatctcgc ccaagccttt aaaacggctg atggaataag cagtttcttt
     5701 aaagccttct ttttgtagtc gctccaaaat gctgtcgagt tcgttttggt cgagggcgta
     5761 gaatttgcgg gcgggtttgt ttttgccttg tgcgttgaca tcgacgcgga acagcggcgg
     5821 ctgggcgacg tagatgtgtc cgtcggcgac cagtttcggg aagtggcggt agaacagggt
     5881 cagcagtaaa acttgaatat gagagccgtc cacgtcggca tcggacagga tggcaatttt
     5941 gccgtagcgc aggccgctta agtcgggatg gtcgttaatg ccgtgcggat cgacgccgat
     6001 ggcgacggaa atgtcgtgga tttcggcgtt gccgaagagt tggtcggggt ggacttcaaa
     6061 gctgttgagc actttgccgc gcaggggcag gatggcttgt gtggctttgt cgcgggcgag
     6121 tttggcggag ccgccggcgg aatcgccttc gacgaggaag agttcgtttt cgcggatgtc
     6181 ttcgctttcg cagtcggtca gtttgccggg caggacggcg acgccgctgc cttttttctt
     6241 ttcgattttt ttaaccgaac gcatccgtgc ctgtgcttgg cggatggcga gttcggcgat
     6301 ttttttgccg aagtccacgt tttggttcag ccacaattcc aaagggtcgc ccgatacggc
     6361 ggcgacgagt ttcaacgcgt cgcggttggt cagtttgtct ttggtctgac cttgaaattg
     6421 cgggtcgagg acacgggcgg agaggacgaa ggcggttttg ccgaacacgt cgtcgctttg
     6481 tactttcacg ccgcgcggca agaggttgtg cagattgatg aagttgttga cggcgttgaa
     6541 cacggcttgt ttcaggcctg cttcgtgtgt gccgcccaga ggggtgggaa tcagattgac
     6601 gtaactttcg ttggcacacg agccttcttc cagccaagtc agggcaaacg cggcgccttc
     6661 gccgatgctg aaatcgccgt tgtggtcgtc tgaaatatag ttttcgcagg agaacagcgg
     6721 cacggcttct tgcgcgtcgg caatcaggtc ggtcaggtag cttttcagac cgtcggggta
     6781 atgccaggtt tgagtgcgcg cttcgtcttc gcctttgacc ggacgggtca gggaaacgcg
     6841 tacgcccggc agcagcacgg ctttggcgcg cagcaggcgt tcgagttcgg gaatgctgta
     6901 attcgggctt tcaaaatatt tgccgtccgg ccagacgcgc acttctgtac cgctgtcttt
     6961 gacggcgcat ttgcccactt gtgccaacgg ttcgaccacg tcgccgccgg caaacacgat
     7021 gcggtggatt ttgccttcgc gtttgaccgt tacttcaagg cgggtggaaa gggcgttggt
     7081 gacggatacg cccacgccgt gcagaccgcc agaaaaggca tacgcgctgc cgccgtcttt
     7141 tttgttgaac ttgccgcccg cgtgcagacg ggtaaacacg agttcgacca cggatacgcc
     7201 ttcttcaggg tgcaggccga cgggaatacc gcggccgtta tcacggacgg aaagcgaacc
     7261 gtcttcatga atttgcacgt cgattgcagt cgcgaaacca cccaacgcct cgtccgccgc
     7321 gttgtcgatg acttcttggc agatatgggt cgggctgtcg gtgcgggtgt acataccggg
     7381 acgttctttg accggttcca aacctttgag gacggtgatg ctggattcgc tgtattggtt
     7441 gtttttagcc ataggaataa tctgaaagta agaaaaacaa cgctttcaga cggcctgaaa
     7501 gcgttgcgtt ccgttgtttt accggttgcc ggaaggttgg cgggcggcaa agtcttcata
     7561 actttccata ccgcgcagga agcgggaaga gagttctttc aacgccccca aataaacgtc
     7621 gcgtttgaac tcgatgactt cgtcaacggg cgcccaatat tgatgccaac gccagccgtc
     7681 aaattcgggg tggcgggtgg cgcgcaggtt gacatcgcaa tcccggccgg tcaggcgcag
     7741 gagataccaa atctgcttct gcccgcgata agagccgcgc cattcgcggc gcacccagtt
     7801 gttcggcacg tcataacgca gccagtcgcg cgtccgcccg acgattttga cgtgttgcgg
     7861 cagaagtccg acttcttcgt aaagctcgcg gtacatcgcg gtttcggggc tttcgcccgg
     7921 cttgatgccg ccttgcggaa actgccaaga atgttcgcgc acgcgcttgc cccaaaagac
     7981 ttcgttacgt tcgttaatca ggataatacc gacattgggg cgatagcctt ccctgtccaa
     8041 cacggtgtcg ccctccgtta aattcaatcg tacgattttc ccacaaatcg ggcggttttg
     8101 acaaatcaga cggcatggtt caagcatgtc gaaacacaga cggactcggg aaaatatctt
     8161 aaatttggtt tacaataatg tgtttcaaat tattcgggaa tcagaccatg ttagatatcc
     8221 aattgctccg cagcaacacc gccgctgtgg cggaacgctt ggcggcgcgc ggttacgagt
     8281 ttgatgccgc gcgtttcaat gcgctggaag aacaacgcaa agccgtccaa gtgaaaaccg
     8341 aagaactaca agcctcgcgt aacagcattt ccaagcaaat cggcgcactg aaaggtcagg
     8401 gcaaacacga agaggcgcag gcggccatgg atcaagtcgc ccaaatcaaa accgatttgg
     8461 aacaggctgc cgccgatttg gatgccgttc aaaaagaatt ggacgcatgg ttgttgagca
     8521 tacctaacct gccgcacgaa agcgtacctg ccggtaaaga cgaaaccgaa aacgtcgaag
     8581 tccgcaaagt cggcaccccg cgcgaatttg actttgaaat caaagaccat gtcgatttgg
     8641 gcgaaccttt gggtttggat tttgaaggcg gtgcaaaact ctccggcgca cgatttaccg
     8701 tgatgcgcgg acaaatcgcc cgtctgcacc gcgccttggc acagttcatg ctggatacgc
     8761 acacgctgca acacggctac accgagcatt acacgcctta tatcgttgac gatacgacgc
     8821 tgcaaggtac gggccaacta ccaaaatttg cggaagatct gttccacgtt acccgtggcg
     8881 gcgacgaaac caaaaccacc caatacctga ttccgacagc cgaagttacc ctgaccaata
     8941 ccgttgccga cagcattatc ccgtccgaac aactgccgct gaagctgacc gcgcattcgc
     9001 cctgtttccg cagcgaggcg ggttcgtacg gcaaagacac gcgcggtctg attcgccagc
     9061 accagttcga caaagtggaa atggttcaaa tcgttcatcc cgaaaaatca tacgaaacgc
     9121 tggaagaaat ggtcggccat gccgaaaaca tcctgaaggc tttggaactg ccctaccgcg
     9181 tgattaccct gtgtaccggc gacatgggct tcggcgcggc aaaaacgtat gacttggaag
     9241 tttgggtgcc ggcgcaaaat acctaccgcg aaatctcaag ctgctccaac tgcgaagatt
     9301 tccaagcccg tcgcatgaag gcgcgtttca aagacgaaaa cggcaaaaac cgcttggtac
     9361 atactttgaa cggctccggt ttggcagtcg gcagaacctt ggtcgccgtg ttggaaaacc
     9421 atcaaaacgc cgacggcagc atcaacatcc ctgccgcact gcaaccgtat atgggcggcg
     9481 ttgccaagtt ggaagtgaaa taagccttaa ccctgaacat aaatgccgtc tgaaacttgg
     9541 ttcagacggc atttccttta aacttttaaa acacgtcagc cgtcggcacg aaccgcattg
     9601 ccgcaatcgc cggtctgtcc gacctcgcgg atattggaca gcgtaacttc cgaaatatta
     9661 cccaacgcct cttccgtcaa aaatgcctga tggccggtaa acagcacatt atgacaagac
     9721 gacaggcggc ggaacacgtc gtcggtaatc acatcgttgg atttgtcttc aaaaaacagc
     9781 tcgcgctcgt tctcgtacac atccatgccc aatgcgccga ttttccggcg tttcaacgcc
     9841 tcaatcgcgg cggcactgtc aatcagcccg ccccggctgg tgttgataat catcacgccg
     9901 tctttcattt tgtcgaacgc cgcttcgttc agcatatagt ggttttccgg cgtggagggg
     9961 caatgcagcg tgatgatgtc cgactgggca tacagctcgt ccaaatccac atattttccg
    10021 ccgagttttt ccacttcggg gttgcaaaac ggatcgtaag ccagcaggtt catgccgaaa
    10081 ccctttaaaa tccgcatggt tgcaataccg attttccccg tgccgataac gcccgccgtt
    10141 ttgccgtaca tattgaaacc ggtcagacct tccagcgaaa aattcgcatc gcgggtacgc
    10201 tgataggctt tgtggatacg gcggttcaaa gtcagcatca gaccgaccgt atgttccgca
    10261 accgattcgg gcgaataggc aggcacgcgc acgactttca agcccaactc ttcagccgcc
    10321 tttaaatcca cattattgaa gccggcacaa cgcaacgcca cagttttcac gccaatttgc
    10381 gccaattttt ccaacacggg ccggctgccg tcgtcgttta caaaaataca aaccgcttcc
    10441 gcgccttccg ccattttcgc cgttttcgca tccagcataa aatcaaaaaa ctccagctcg
    10501 aagccgaaat gccggttggc gcgggtaaaa tgttcgcggt catagctttt cgtaccgtaa
    10561 atcgcaatct tcatcaatat gtccagttgt cgcctatggt tgagaaacgg cataatacac
    10621 tgaattcaaa caaatcagta gaatatggca gattaaaatt gattgcatgc acggcatttc
    10681 catttcaaaa cacaaaactc aatcgcccat tgccgccaaa agctccgcct gatgttcggc
    10741 aatcagggca tcggtgattt ctgccaaatc gccgtccatc acaaaatcca gcttgtgcag
    10801 ggtgaggttg atgcggtggt ctgttaccct gccttgggga tagttgtagg tgcggatgcg
    10861 ttcgctgcgg tcgccgctgc cgatgaggga tttgcgttcg gcggcttctt tggcttgggc
    10921 ttcgcgtttt tgcgcgtcgt tcaggcgggc ggcgaggact ttcatcgcct gcgctttgtt
    10981 ggcgtgttgg ctgcgtccgt cttggcattc gaccaccatg cctgtgggca ggtgggtgat
    11041 gcggacggcg gaatcggttt tattgatgtg ctgcccgccc gcgccggatg cgcgaaaggt
    11101 gtcgatgcga aggtcggctg ggttcagttc gatgtcttcc agttcgtccg cttcgggcat
    11161 gacggcaacg gtgcaggcgg aggtgtggat gcggccttgg ctttcggtgg cggggacgcg
    11221 ctgcacgcgg tgtccgcccg attcaaattt caaacggctg tacgcgccta agccgataat
    11281 acgggcgata acttctttat agccgcccaa ctcgctttcg ttggcggaca cgatttcaac
    11341 ctgccagcgg ttgcgttcgg cgtagcggct gtacatacgc agcaaatcgc tggcaaacag
    11401 cgcggcttcg tcgccgccgg taccggcgcg tacttcgata aagatgtttt tgtcgtcgtc
    11461 ggcatctttg ggcagcagca atttttgcag ttcggtatcg agcgcaccga ttttggcttt
    11521 cgccgcttcg atttcttcgg cggcaaagtc tttcatttcg gggtcggaca acatttcttc
    11581 ggcatccgcc aagtcgcttt gggcaagccg atagttttgg aacacttcga cgacgggggt
    11641 cagttcagcg tgttcgcgcg tgagcttgcg gtagttgtcc atatcggacg tggcttcggg
    11701 ttgccctaaa aggtgggtaa cttcttccaa ccggtcgccg agttgttgca gtttttctaa
    11761 gatagacggc ttcataattc ttccataaca aacgccgcct gaatgttcag acggcatcaa
    11821 aacgcggtca ttataatata ttttctgaat attcaaaaag ataatctagg gacggagcag
    11881 gctgtcggca ttgcgttccg ttatcgcggc gatttccgcc gcgccggtac cgcgtatctg
    11941 cgcggcaatt tcggcaatcc gaagaatgtt ggcaggcgta ttgacggtgt ttttcaacat
    12001 aaacgggcta tccgtttcca atacgaaatc cccgtcgttc aaggctttaa gcgtatcgcg
    12061 cactttacgc gcgttcggat tgagcaacaa cgaaccgatg ccgattttga aacccagttt
    12121 cgtcaacacg cgcgcttctt ccgcgctgcc tgagaaggcg tgaacgatgc cgccttgggc
    12181 aaagcctgtc tgtttgacag cggcggcgat gtcggcggtg gctttgagat tatggataat
    12241 cacgcggcgg cgcagggttt gcgcgatggc aagctggcgg acgaaaactt ggatttgccg
    12301 ttcgcgctgc ggcggcgttt gggttttgtc gtaaaaatcc aagccgattt cgccgaccca
    12361 tgcctgcgga taacgtgcca acatcgcttc caggcggacg caatcacgct cggcaatgcc
    12421 gtctgaaaac caaggatgga tgccgagcgc aatacggatt tgaccgtgtt cggacggcat
    12481 ttccgacagt tccgccacgc tttgccaatc ctgcggacag gtggcgggaa cgataaaccg
    12541 cttcacccca actttccgcg cggcggtcag gatgtgcggc aggttttcgc gcagggcggc
    12601 atcggcaagg tggcagtggg tgtcggtgaa gttcatttcg attccgcaat gcggcaggtt
    12661 cacataaaaa taaggcaggg cggcaaggga tgctgtgtac gggcggcgca taaggcgcgg
    12721 tcaacgcccc gtcattgcca tttcaatccg ctataacttc agtcttgcca actctttttc
    12781 cacctcttcc ttaccccagc cttgcgatac ggcgagggtc atgagtgcgg tggcggtttc
    12841 gaggttgcat ttgccgccgt tgatgatgcc tgagttgcgg aacgcgttgc cttgcgcgta
    12901 aacggcagcg gttctgcctt gtcggacttg gctgatgttg agcagcagtt tgccctgccg
    12961 cgcgaagtct cggacggcgc ggataaaacc ttcgtctgcg ggcgtgttgc cgtgtccgta
    13021 gctttgcagg ataagggctt gggcgggaaa ctgtccgagt ccgtcggcaa gttcttggac
    13081 ggcaaagccg gggataagcg tgcggacggc gatttttgcc tgcgggtcgg gataacggat
    13141 tttgaggccg tctgaaacat ctgccgcgtc ctgattcggg atgcggacat tgtgccagcc
    13201 ccgggtttcg tcccactccg ccagtgcgcc gaaatgcgga ttgtcgaaac cggcggcggt
    13261 ttcggtgctg actttgctgc tgccgacggc gggataaagt ttgccgtcaa aggcaataag
    13321 cgtctgcttc aatccgagtg ggaatgcggc aacggcagtc gccagattgc gcggcgcgtc
    13381 gctgcccacg gcgttgtacg gccattggga accggtcagg acgattggct tgtccaaacc
    13441 ctgcagggcg agggcgaaca gattggcggt ataggcgagc gtgtccgtgc cgtgcagcac
    13501 caaaacgccg tcgtactgcg gcagcgcggc ggcaatgatg tccagccaag cgcaccagtt
    13561 ttgcagttgg acggcggaag aatcaatcag cggcccacaa acgtgccaat cgaaatccat
    13621 gccgtttgaa aacggcgcga gtgcctgccc gaccaacgcg gtatcggggc gcaggccttc
    13681 gctgctttgc gtcatgccga tggtgccgcc ggtataaagg acaaaaattt tctgtttcat
    13741 ggctcatcct gaaaatgcaa agaccgcctg aaacgcgaaa tgcgtccgga cggtcgaaaa
    13801 tctgatttac tgctgcttct gtgccgcttt tttcgctgcc ttttccgcct tgcgtttggc
    13861 gcgtttttcg ctcaattgtg cgcggtaaag ctgataatgt cggcgtttgc gccaccagaa
    13921 ccacgccagc gccgccgcca gcacgcccaa tgcgatgaag atgccggatt gcaggctgtg
    13981 cattttcgcc atcagccaat cgatgttgtg cgcgccgtac tcgcccaagt aaatccaaac
    14041 gggcacggaa atcagcgcgg caagcccgtc cataatcaga aagcgcagat acgatacttt
    14101 gcggctgatg ccggcggtaa cgaaaacggc agtccgcaaa ccgggcagga aacgagcgac
    14161 aaataacacc cagttgccgt atttgtcgaa tttttcctga acctgtgcgt aacgtttcgg
    14221 cgtcatgatg cgcgcaatcg gtttgaactt gaggattttc tgcccccaga tgcgtccggc
    14281 ggcgaacatg atgccgtccc cgaccaatac gccgagcata ccgactgcaa acataatatg
    14341 cggattggta taacccatac ccgaaatcac gccgcctgtt accaaggtca aatcctcggg
    14401 aatcggcacg ccgaaaccgc agatgaccaa aacgaaaaac acggccgcgt agccgtattc
    14461 gacaaaaaag gcttccaaaa gggcaaacat agcggatatt ccattgtcgg agataaaaag
    14521 tcagaacaag ccgaaacatt ttctgcgcga aacggcattc tatcaaagat tatgccgtct
    14581 gaaagcggca gggggcagat tcgcgtgccc gccgcccgtt cagacggcat ttaaacagaa
    14641 aaccgcccgg ttctgaaaac ggttttgcct gattttgcct aaatgccgcc gatggcggcg
    14701 gcgatacgtt ccgccccgtc gcgcgcccaa tccgcctgcc gcgcttcaac catcacacgc
    14761 acgacgggtt cggttcccga agcgcgcaac acaacccttc ctttgccttc gagttctttt
    14821 tccacttccg ccaacacgtc ttttgaggct tcctgccatt tctgaccttt ttggatgcgc
    14881 acgttaatca tcgtttgcgg atacggctgc caatcggcgc aaacggtggc gaggtcttgg
    14941 ttcagcgttt gcagtgccgc caaaacttgc agcgcggaaa taatgccgtc gccggtgttg
    15001 tgtttgtcca tgcacaaaat atggccgctg gcttcgccgc cgatgagcca gccgcgttgg
    15061 ttcagctgtt ccaacacata gcggtcgccg actttggcgc ggcagaaatc cacgccctgc
    15121 tctttcaggg cgatttccat cgccatattg gtcatgaccg tgccgaccac gccgccgatg
    15181 ttgatacctt ctcgggcgcg ggctttagca atgacgtaaa tcaggctgtc gccgtcgtaa
    15241 accttaccgt ttttatcgac catcatcagg cggtctccgt cgccgtctaa ggcgatgccg
    15301 tagtcggctt catgctgtaa aacggctgcc tggagtgtct tggtataagt cgcaccgcat
    15361 ttttcattga tattgtagcc gttgggttcg tcgccgatgc tgacgacttg tgcgcccagt
    15421 tcgtgaaaca ccttgggtgc gacaccgtac cccgcgccgt tggcggtatc gataaccaac
    15481 ttcaaacccc gaaggtcgga atggctggga aaggtagatt tgcaaaattc gatatagcgg
    15541 tcgtccgcac cactgatgcg gcgtgcgcga ccgaggcgtg cagaaggctg ggttttcatt
    15601 tcttcgtcga ttttggcttc gatttccaac tcgatttcat cgctcagttt cacgccgccc
    15661 tcggcaaaga atttgatgcc gttgtcggaa taggcgttgt gcgacgcgga aatcatcacg
    15721 ccggcggaca ggcgcaacgc gcgggtcaga taagccacgc cgggcgtggg cagcggtccg
    15781 gtctgtacca cattcacacc cgccgccgta aaaccggcca ccaaagcggc ttccagcata
    15841 tagccggaaa tgcgcgtgtc tttgccgatg aggacggtcg gtttttggtc ggtgtcgtgc
    15901 tgcaccaaaa cctgccccgc cgcatagccg agtttcaata caaaatcggg cgtaatcgga
    15961 aactgcccga cttcgccgcg cacgccgtcc gtgccgaaat atttttttgc catgtgttgc
    16021 tccgagaatg tgaaccgttg tccgagatta tacagtctgt ttgtgccctg ctgtctgcac
    16081 cgttgatgcc gtctgaagcc gccccgtcct tttcagacgg catgaagtat gcgaaccgct
    16141 gtttacagat tgatgcccaa cgcttcccac accttcaacg cgtccgccgt cgccttcacg
    16201 tcatgcaccc gcacaatttg cgcgccgcgc gccacggaag ccagcgccgc cgccacgctg
    16261 ccgtgtacgc gtgccgccgc gtcggtttcg ccggtcagct cgcctatcat gctcttgcgc
    16321 gatacgccga taagcagcgg caaaccggtt tccgccatca attcgggcaa atgccgcatc
    16381 agtgcgatat tgtgttgtaa ggttttgccg aagccgaaac cggggtcgag tgtgatgcgt
    16441 tgtggggcga tgcctgccgc aatacattcc gccgcccgcg ctttcaaata ccgcgtcact
    16501 tcaccgacaa catcctgata tttcggatta atctgcatgt ttttaggcaa accctgcatg
    16561 tgcatcaggc aaatacccgt gtccgtctgg cgcgccagca attcgagcgc gccttcgtcg
    16621 gtcaacgccg ccacatcgtt aataatatcg atgccgccga gtgccaacgc tttttccata
    16681 accgccgtgt ggcgcgtgtc caaactgacg ggaacacccc accccgccac ttccgccaaa
    16741 acaggcgcaa cccgcgccca ttcttcttca ggcgaaacat aatccgcacc cggccgcgtc
    16801 gattcgccgc cgatgtcgag aatgtccgca ccctctttca aaagccgttc ggcgtgcgcc
    16861 aaagcggttt tggcgttttg cgaatacgcg ccgccgtcgg acaaagaatc gggcgtgaga
    16921 ttcacgatgc ccatgatttt cggcttgtcc aaaccgattt caaaccgtcc tgcctgccaa
    16981 acgtgtcgtg ccatctgaac tcctcccaaa ataaaaaaca gattatatgc cgtctgaaac
    17041 cgtcttgtgc gcttcagacg gcaccgctat tcgggcggca gacggcatgt tgtccgaata
    17101 tctgctccgc ctttgaatct gccggtatgc ctgctatccg cccgactttt caaaacaggt
    17161 tccgacgatt ccgcacgcgc ctgccgcctt tgccaagccg tacaggattt cctgcggcat
    17221 atcgcggttc cataatcccg taatattcgc aatcacgggc agatggctga tttggcggac
    17281 tttcacgatg gattcgacat ccaaacggta gggatggtct ttggtatggc tcaacacgcc
    17341 cgactcgccc agaatcaggt ggcggttgcc gcgcgagacg acatattctg cggcattcaa
    17401 ccaatcttcg gcagaatggt gcttgtcttt acacagcacc aagggaatgt tcaggtttcc
    17461 ggcttcattc aatacggcaa gatcggacat cagcccgccg cccaaataca ggatgtccgc
    17521 ccccgcattc aaagccgctt cgacatggcg gacgttgcgg acgcgcacca atacgggttt
    17581 ccctgcgcca tgcgccgatg cggtctgttc cgccaaccgt ctgcaccgtc cccgcccttc
    17641 atccgcactt gaagtgtcgt ataagtttgc cgaagtgaaa aacggatcta gaaacactgc
    17701 atccgcattg cgccatactg acggttctgc ggcgatacgg acggtttccc cgccgccgaa
    17761 agccacgcct ttggcggcaa cgcggctgtc ttccgcccga ttttcccgac tgacggtttt
    17821 ccatgtatcc aaaatgcgga cggctttctc gacctccggc agcgtctgca cctccctgac
    17881 gctcaaaacc ctatcgtcgc cgattgcgcc gatgacggta cgctcgtcgc cgtgagaaat
    17941 gtgttctcgc agacctctgc tgcggataaa ggcgacaacg ccggcaatgt ccgcttcggc
    18001 ggcacgcctg ctcatgacaa taatcatatt tcctcctgac acaagaaacg gcctgcccaa
    18061 aataggattt ttgcaagccg tgttatactg tggcgtgttt tacagattgt tcgggctatg
    18121 gatttattat cggttttcca caaataccgt ctgaaatatg cggtggccgt gctgacgata
    18181 ctgcttttgg cggcagtcgg gctgcacgct tccgtatatc gcaccttcac gcctgaaaac
    18241 atccgcagcc gcctccaaca aagcattgca cacacacacc ggaaaatctc gtttgatgcg
    18301 gacattcagc gcaggctcct gccccggccg accgtcatcc tgaaaaacct gaccattacc
    18361 gaacccggcg gcgaccagac tgccgtttcc gtccaagaaa ccaaaatcgg attgagctgg
    18421 aaaaacctgt ggtcggatca gatacagatt gaaaaatggg tggtttcgag tgcggaactt
    18481 gccctgacgc gcgacgggaa aggtgtttgg aacatccaag acctgatcga cagccaaaaa
    18541 cgccaagcct cagtcaaccg cattatcgtc gaaaacagca ccgtccgcct caatttcctg
    18601 caggaacagc ttatcctgaa ggaaatcaac ctcaacctgc aatcccccga ttcgtcgggg
    18661 cagccgtttg aaagttcggg catactggtt tggggaaagc tgtccgtccc gtggaaaagc
    18721 agggggctgt tcctttcaga cggcatcggc acgcccgaaa tctcaccgtt ccattttgaa
    18781 gcttccactt cgctggacgg acacggcatc accatttcca ccaccggcac acccgccatc
    18841 cgtttcaacg ccggcggagc ggatgccgcc ggcctcggcc tgcgtgcaga cacttccttc
    18901 cgcaacctcc acctgaccgc ccaaatcccc gcgctggcac tcaggaacaa cagcattaaa
    18961 attgaaaccg tcaacggcgc atttaccgcc ggcggcgaat atgcccgatg ggacggttcg
    19021 ttcaaactcg acaaagccaa cctgcactcc ggcatcgcca acatcggcaa cgccgaaatc
    19081 tccggcagct tcaaaacacc gcgccaccag accaacttct ccctcaattc gccgctcgta
    19141 tggacggaaa acaaagggct ggacgcgccg cgcctgtatg tatcgaccct tcaggatacc
    19201 gtcaaccgcc tgccgcaacc ccgtttcatc agccggctcg acggttcgct gtccgtaccg
    19261 aatctgcaaa attggaatgc cgaattaaac ggcacattcg accgccaaac cgttgccgcg
    19321 aaattcagat acacacatga agacgcaccg catctggaag ccgccgtcgc actgcaaaaa
    19381 ttgaacctga ccccctatct tgacgacgtg cggcaacaaa acggcaaaat atttcccgac
    19441 accctcgcca agctgtccgg cgacatcgag gcgcacctga aaatcggaaa agtccaactt
    19501 cccggcctgc aactggacga tatggaaacc tacctccacg ccgacaaagg ccatatcgcg
    19561 ctcagccgtt tcaagtcagg gctttacggc ggccataccg aaggcggcat cagcatcgcc
    19621 aacacccgtc ccgccactta ccgcctgcaa cagaatgcaa gcaacatcca aatccaaccg
    19681 ctgctgcaag acctgttcgg cttccacagc ttcagcggca acggcgacgc ggtcatcgac
    19741 ctgaccgcgg gcggcgaaac ccgaaaagag cttatccgct cgcttcaggg cagcctgtcg
    19801 ctaaatattt ccaacggtgc atggcacggt atcgacatgg acaatatcct gaaaaacggc
    19861 atttcgggca aaactgccga caatgccgca cccagcacac ccttccaccg attcacgctc
    19921 aacagcgaaa tttcagacgg catcagccgc cacatcgata ccgaactctt ctccgacagc
    19981 ctctatgtta ccagcaacgg ctataccaat ctggatacgc aggaattgtc tgaagatgtc
    20041 cttatccgca acgccgtcca tccgaaaaac aaaccgattc ccctgaaaat caccggtacg
    20101 gtggacaaac cgtccattac cgtcgattac ggcaggctga ccggcggcat caattcgcgc
    20161 aaagagaaac agaaaatcct cgaagacacc ctgctggaac aatggcagtg gctcaaacct
    20221 aaagaaccgt aaacatcctg cgtacacaaa tgccgtctga aacgcccccg cgcttcagac
    20281 ggcagaccgt aaaacctaca accccaattc ctcccaaatc ccatcaatct tagccgtaac
    20341 cgcagggtct tttttgatga cgcgtcccca ttcgcggtcg gtttctcccg gccatttgtt
    20401 ggttgcgtcc aagcccattt tgccgccgag tccgctgacc gggctggcga agtcgagata
    20461 gtcgatgggc gtgttttcca ccaaaacggt gtcgcgcacg gggtccatgc gcgtggttac
    20521 cgcccagatg acttctttcc agtcgcgcac gttcacatcg tcatccacca cgatgatgaa
    20581 tttggtgtac ataaactggc gcaggaacga ccagcagccc atcatcacgc gcttggcgtg
    20641 tccggcgtac tgttttttca tgctcaccac cgccatgcgg taggagcagc cttcgggcgg
    20701 caggtaaaaa tcggtgattt cggggaactg cttttgcaag agcggtacga acacttcgtt
    20761 caatgccacg cccaaaacag cgggttcatc gggaggtttg cctgtgtagg tcgaatggta
    20821 aatcgggttt tcgcgcatgg tgatgcgctc gaccgtaaat acagggaaat gatcctgctc
    20881 gttgtaatag ccggtgtggt cgccgtatgg gccttccaac gcggtttcgt tcggatgaat
    20941 cacgccttcc aatacaattt cagcacgggc aggcacttgc aaatcgttgc cgatacattt
    21001 caccagctcc gtccgcgaac cgcgcagcag tccggcaaac tggtattcgc tcaaagtatc
    21061 gggaacaggc gttaccgctc cgagaatagt ggcagggtcg caaccgagca cgacggcgac
    21121 aggatacggc gtatcgggat tgagtttgcg gaattcctga taatccagcg cgccgccgcg
    21181 atgcgacagc cagcgcataa tcagcttatt tttgccgatt aattgttggc ggtaaatgcc
    21241 gagattttgg cgttttttgt gcggaccgcg cgttacggtc aagccccacg ttaccagcgg
    21301 cgcaacgtct tccggccagc aatgctgaat cggaagttta tacaaatcaa catcttcccc
    21361 ttcccacaca atttcctgac acggcgcgtt tttcaccacg ttcggcgcca tgctccaaat
    21421 atctttcagc aatggcagtt tggaaaacgc gtctttaatg cctttgggcg gttcgggttc
    21481 tttcagatac gccagcgtct gcccgatttc gcgcagcttg gacacgctgt ccgctcccat
    21541 gcccatcgcc acacgttcgg gcgtaccgaa caggtttgcc aacacgggat aaccgtagcg
    21601 cgtaccgtca ggcttaatcg gattctcaaa caacaatgcc gacccttcgg cgcgcagcac
    21661 gcggtcggcg atttcggtca tttccaaatg cggggaaacg gggtgcgcga tgcgtttgag
    21721 tttgccctgc tgctcgagca tggcgatgaa gtcgcgcagg tctttgtatt tcatatttat
    21781 cctttttgtc cttttatcct gaacaatccg attcggatac cgctcctatc cttgcctgtg
    21841 cctcggcata ttctatgccg tgataaaagt cgcgtaccag cggatgtccg ccgctttgat
    21901 gaagttgcag caaagggcgt tgaccatcgg gttgggtaac gacattacaa tgcaaaccga
    21961 aggtgtcgga ttcgtaaggg ggcagccgat tgcaaatcat accgaaataa acgacgtttt
    22021 ccggattgtc gtgaaaatgg ctttgatagt cgttaaaact cttttcactg acagataccc
    22081 ataccccata ttccagcgtt tcctgatgcc cgataatcgg aatcggcagc accgcgcgga
    22141 taaaacggtc ggtttgaacg ggatagcgga tgatgcagaa atcagaatca cattccgctt
    22201 gataagcaat gcgttcttct tcactgagtt gattataggg atagggggcg gtaaagccga
    22261 ttgcgggcat atcttcatgt ttttcgccgc aggaagtgca agtgtacata aggtttcaga
    22321 ctttcaaaac gagtttgcgg taaagccatt cgccggcaaa cggcatcccc atcaatacat
    22381 aggcaatcac gcctgtataa accgcccacc aatcatatcg ccccaaccgt accaacaaag
    22441 cggcaagcgt cccgttggca ataaagaata cgcaccaaac ctgcgttacc cggcgggtat
    22501 agcgcacagc tttttcaggc aggtcgggct gttgcggccg cgcgagcctt tctatgaccg
    22561 tctgtccggc aaacaggctg ccgccgaaca ccgccaacat catcagattg acgaggacgg
    22621 gataccaata catcgaatca tgccgcccga acaccaatac tgcggcaaaa aacagtgtaa
    22681 taaacaaagc cgcataacgc tgttggggca gtttggcagt cagggcgcgc agcagccaca
    22741 acccgcacat cgccgccgcc agccagacaa accagcccgc ctccctgccg taatgatagt
    22801 ggattaacaa aaaccagtac agcgttgcct cgccttgccg tactgtctgc ggcttcgtcg
    22861 ccttgtcctg atttttgtta atccactata ccacaaagcg ggataggcaa tgcttaatac
    22921 ggtcagaaaa atatgtccga aaaaaccggg tttcattttg aatccgcaca aatgttttca
    22981 gacggcatcc gataaaaaca tgccgtctga aaaataatta gaaatacccg attagcccgc
    23041 ctgaatcttc aataccgcct gtaccacgtc gttgacggtg cggacattgc ggaaatcttc
    23101 agcctgcagc ttgcgggctg ccacagccat tcacgattgc gatatacccg gcggcattcc
    23161 cgactgccgt tcagcagaaa gcgcacccat tccaaaccgc tccaatatgc ctcgggcagc
    23221 ataccggctt cagacggcat atcgtccgaa gcagacagag tcaggctgta acgcgtccct
    23281 ttggtcagaa ccatcgccaa agcataagca aacggcgcgc gcgttgccga tacggcatat
    23341 ccttccggca gcggatcgtc cgccgccaaa accaaaaccg acccgcatcc ctcttccaac
    23401 agtgatgccg cttccgccaa tgccgtttcc acaccgtcgg cacacacggc caatgccgtc
    23461 tgctcgctca tatcccgcct caatatcaac cattaccccg ccgttgcatt gtgcaccgac
    23521 aaaccgaacg aagtcggcga cacggtttgc gatttcaaca gttccaacca caaatcgaaa
    23581 ctgcgcgcca tttccccgtc gtgcgaggca taaactatag tggattaaat tttaggggct
    23641 gtactagatt agcagatatg ttaccctggg aatatgaaga taacacactg caaattaaag
    23701 aaaaaagtac agaaagaact gatccgtttt tttgtactcg aagttaccgc ccgttctgcc
    23761 gccgatattt tgggtatcca tcccaattcg gcagcactgt tctaccgtaa aatccgcacg
    23821 gttatcaacc atcatttggc cttggctgcc gatgaggttt ttgagga
//
LOCUS       DAXIDM010000021        23621 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000021 DAXIDM010000000
VERSION     DAXIDM010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23621
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.021"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            62..763
                     /locus_tag="ACFOAE_000687"
     CDS             62..763
                     /locus_tag="ACFOAE_000687"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFC6884218.1"
                     /translation="MSLKTVAVIGAMEQEIELLREMMENVKTVSFGRFSAYEGELAGK
                     RMVLALSGIGKVNAAVATAWLIHQFAPDCVINTGSAGGLGKGLKVGDVVVGTEIAHHD
                     VDVTAFGYVWGQVPQLPARFASDGILIETAKRAARTFEGAAVEQGLIVSGDRFVHSSE
                     GVAEIRKHFPEVKAVEMEAAAIAQTCHQLETPFVIIRAVSDSADEKADISFDEFLKTA
                     AANSAKMVAEIVKSL"
     gene            905..2698
                     /gene="lepA"
                     /locus_tag="ACFOAE_000688"
     CDS             905..2698
                     /gene="lepA"
                     /locus_tag="ACFOAE_000688"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFC6884219.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLADRFIQYCGGLDLREMSTQVLDSM
                     DIEKERGITIKAQTAALNYKARDGQVYQLNLIDTPGHVDFSYEVSRSLSACEGALLVV
                     DASQGVEAQTVANCYTAIDLGVEVVPVLNKIDLPAADPERVEQEIEDIIGIDAVGAVQ
                     CSAKSGIGVEDVLEEIVAKIPAPTGDENAPLQAVIVDSWFDNYVGVVMLIRVKNGTIK
                     LKDKVRFMSTKAETQVEQLGVFTPKSVQKQELKAGEVGFLITGVKELGQAKVGDTVTL
                     VANPATEPLPGFQEVQSQVFAGLYPVESHDYEALRDALEKLQLNDASLKFEPEVSQAL
                     GFGFRCGFLGLLHLEIVQERLEREFDMDLITTAPTVVYEVVLKNGEKIEVENPSKLPD
                     IGSIETILEPIITATILVPQEYVGNVMTLCNQKRGVQVNMQYMGRQVMLTYDLPMNEV
                     VMDFFDKLKSTSRGYASLDYHFKEFQPSDLIKLDIMVNGEKVDALSLIVHRQSAVHRG
                     RELASKMRELIPRQMFDIAVQAAIGSQIIARENVKALRKNVLAKCYGGDITRKKKLLE
                     KQKAGKRRIKQVGNVEIPQSAFLAILQVSDK"
     gene            2843..3862
                     /gene="lepB"
                     /locus_tag="ACFOAE_000689"
     CDS             2843..3862
                     /gene="lepB"
                     /locus_tag="ACFOAE_000689"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFC6884220.1"
                     /translation="MNTMLMSGAAAALLAGIILYFKSDKKRQENGEWSSGLEYAYILT
                     AVGVFAALSLFMSFAAVFLIFVVLCGTAWAVYKYRLKTHPEISESSHFGDYFGSFFPT
                     VLVLFLIRSFIAEPFQIPSSSMRPGLIKGDFILVGKFSYGLRVPVLNNIFIPTGKIER
                     GDVVVFNYPLQPEMTYIKRIVGIPGDVVEYRDKILTVNGKPTSDIPNGTYRYPDDTDP
                     SEIHNTDMFHSGLDGKSFNILKKEGQPAVSLPVLGKYTSDIMSENGYSIEQSGLEHCQ
                     YADDGSGFVCKVPEGRYFAMGDNRDNSADSRYWGFVDDKLVVGKAMFILMNFGDFGRA
                     GTAIR"
     gene            3960..4066
                     /locus_tag="ACFOAE_000690"
                     /pseudo
     CDS             3960..4066
                     /locus_tag="ACFOAE_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(4127..5026)
                     /locus_tag="ACFOAE_000691"
     CDS             complement(4127..5026)
                     /locus_tag="ACFOAE_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC6884221.1"
                     /translation="MGKGGDIVVGNGKKYAAPLLVLGCVVFGLGSLIVRSVPVGSYAI
                     AFWRLLISVFVFWFLARFFGQKFPKNRKTVRYALTAGVFLAFDLALWHESIHAVGPGI
                     STLLNSLQIFFLSAIGVFFFGERLSGLKKAGLISAVAGVAMIAGAEFGYNGNAVWGFA
                     SGLVSGLMLALSMVFVRKTHEIEPVALFPSMMILSLGGAVSLVVPALLMDGGVLYPTT
                     WKDAGLVLVYGVVMQCFAWAMVAYAIPLLSLSLTGLLLLSEPVAALFIDYFGLGKPIE
                     GVQWAGVALTLSAIYLGSLKQQS"
     gene            complement(5297..5430)
                     /locus_tag="ACFOAE_000692"
                     /pseudo
     CDS             complement(5297..5430)
                     /locus_tag="ACFOAE_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(5592..6524)
                     /gene="cysK"
                     /locus_tag="ACFOAE_000693"
     CDS             complement(5592..6524)
                     /gene="cysK"
                     /locus_tag="ACFOAE_000693"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFC6884222.1"
                     /translation="MKIANSITELIGNTPLVKLNRLTEGLKAEVAVKLEFFNPGSSVK
                     DRIAEAMIEGAEKAGKINKNTVIVEATSGNTGVGLAMVCAARGYKLAITMPESMSKER
                     KMLLRAFGAELILTPAAEGMAGAIAKAKSLVDAHPDTYFMPRQFDNEANPEVHRKTTA
                     EEIWRDTDGKVDVFVAGVGTGGTITGVGEVLKKYKPEVKVVAVEPEASPVLSGGEKGP
                     HPIQGIGAGFIPTVLNTKIYDSITKVSNEAAFETARAIAEKEGILVGISSGAAVWSAL
                     QLAKQPENEGKLIVVLLPSYGERYLSTPLFADLA"
     gene            complement(6718..7323)
                     /locus_tag="ACFOAE_000694"
     CDS             complement(6718..7323)
                     /locus_tag="ACFOAE_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884223.1"
                     /translation="MILLHLDFLSALLYAAVFLFLIFRAGMLQWFWASIALWLGISVL
                     GAKLMPGIWGMTRAAPLFIPHFYLTLGSIFFFIGHWNRKTDGNGWQADPEHPLLGLFA
                     VSNVSMTLAFVGICALVHYCFSGTVQVFVFAALLKLYALKPVYWFVLQFVLMAVAYVH
                     RCGIDRQPPSTFGGSQLRLGGLTAALMQVSVLVLLLSEIGR"
     gene            complement(7320..8171)
                     /gene="dapF"
                     /locus_tag="ACFOAE_000695"
     CDS             complement(7320..8171)
                     /gene="dapF"
                     /locus_tag="ACFOAE_000695"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFC6884224.1"
                     /translation="MNTLKFTKMHGLGNDFMVIDAVSQDFTPEDAPIAAWADRFRGVG
                     FDQLLVVGRSETEGVDFRYRIFNADGSEVGQCGNGARCFARFVADKGLTDKKEICVET
                     ANGVIFPKLSDNGMVTVNMGKPKFMPSEIPFVPESGEGDDACIYGVHLESGIQPVSCV
                     NMGNPHAVIVVDDVECAPVRETGSLIEPHRQFPERVNVGFMQVVGRTAIRLRVFERGV
                     GETQACGTGACAAVVAGIRLGLLDEGKTVEVILPGGTLYIEWACGGDVMMTGPAETVF
                     EGELAYS"
     gene            8307..8603
                     /locus_tag="ACFOAE_000696"
     CDS             8307..8603
                     /locus_tag="ACFOAE_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884225.1"
                     /translation="MSRLFLLLFPWAILAACTRNIPANPAVSNCAHLQNRTILYFDAH
                     GKPADDAVKGGFYKIIEIQGANRILIQDFNSTGNALGGFYVPDCRKSSLSAKNI"
     gene            8617..9285
                     /locus_tag="ACFOAE_000697"
     CDS             8617..9285
                     /locus_tag="ACFOAE_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC6884226.1"
                     /translation="MNHDITFLTLFLLGFFGGTHCIGMCGGLSSAFALQLPPHINRFW
                     LILLLNTGRVSSYTAIGLILGLIGQVGVSLDQTRVLQNILYTAANLLLLFLGLYLSGI
                     SSLAAKIEKIGKPIWRNLNPILNRLLPIKSIPACLAVGILWGWLPCGLVYSASLYALG
                     SGSAATGGLYMLAFALGTLPNLLAIGIFSLQLKKIMQNRYIRLCTGLSVSLWALWKLA
                     VLWL"
     gene            complement(9358..11481)
                     /gene="pnp"
                     /locus_tag="ACFOAE_000698"
     CDS             complement(9358..11481)
                     /gene="pnp"
                     /locus_tag="ACFOAE_000698"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFC6884227.1"
                     /translation="MMFDKHVKTFQYGNQTVTLETGEIARQAAAAVKVSMGDTVVLVA
                     VTTNKEVKEGQDFFPLTVDYLERTYAAGKIPGGFFKREGKQSEKEILTSRLIDRPIRP
                     LFPEGFYHDIQIVAMVVSVDPEIDSDIPAMLGASAALVLSGVPFAGPIGAARVGYING
                     VYVLNPTKAELAKSQLDLVVAGTSKAVLMVESEAKILPEDVMLGAVVYGHDQMQVAIN
                     AINEFADEVNPELWDWKAPETNEELVAKVREIAGETIKEAFKIRQKQARSAKLDEAWS
                     AVKEALITEETDTLAANEIKGIFKHLEADVVRSQILDGQPRIDGRDTRTVRPLNIQTG
                     VLPRTHGSALFTRGETQALAVATLGTSRDEQIIDALSGEYTDRFMLHYNFPPYSTGEV
                     GRVGAPKRREIGHGRLAKRALLAVLPKPEDFSYTMRVVSEITESNGSSSMASVCGGCL
                     SLLSAGVPLKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTTEGVTALQ
                     MDIKIQGITKEIMQIALAQAKEARLHILDQMKAAVAGPQELSAHAPRLFTMKINQDKI
                     REVIGKGGETIRAITAETGTEINIAEDGTITIAATTQEAGDAAKKRIEQITAEVEVGK
                     VYEGTVVKILDSNVGAIVSVMPGKDGLVHISQIAHERVRNVGDYLQVGQVVNVKALEV
                     DDRGRVRLSIKALLDAPAREENAAE"
     gene            complement(11715..12578)
                     /locus_tag="ACFOAE_000699"
     CDS             complement(11715..12578)
                     /locus_tag="ACFOAE_000699"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFC6884228.1"
                     /translation="MSEIGLVKIYSGKVRDLYEIDDKRMLMVASDRLSAFDVILDDPI
                     PSKGEILTQISNFWFKKLAHIMPNHFTGQTVYDVLPENEAKVLEKRAVVAKKLTPVKV
                     EAIVRGYLAGSGWKDYQKTGSVCGIRLPEGMQEAQQLPEVIFTPSTKAAVGDHDENIS
                     FEECGRIIGKELAEEVRAKAVRLYTEAAEYAKSRGIIICDTKFEFGLDTNGTLTLMDE
                     VLTPDSSRFWPADQYEVGTNPPSFDKQFVRDWLEQSGWNKKAPAPKVPADVIQKTVEK
                     YREALTLLTQD"
     gene            12777..13640
                     /gene="rfbD"
                     /locus_tag="ACFOAE_000700"
     CDS             12777..13640
                     /gene="rfbD"
                     /locus_tag="ACFOAE_000700"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFC6884229.1"
                     /translation="MRILLTGSKSQLARCLRDRLPEDWETIATDSASLDITDADAVCN
                     MVKSFQPDAIVNTAAYTAVDKAEGDAAAAFAVNASAVYNLALAAHRAHARFVHISTDY
                     VFDGKSKKPYQESDFTNPANVYGQSKTAGELLALSANPDSLILRTSWLFSEYGDNFVR
                     TMLNLARERSPLSAVHNQIGCPTYAGDLAAAIIRLLQQTSPVRGIYHYAGGKSVSWYE
                     FAQHIFQAASQQQTSFPVPELTAVSDKEYPTAAPRPAYSILDCRKIENDFSIKPSDWQ
                     KALAQVVSKLL"
     gene            complement(14165..14398)
                     /locus_tag="ACFOAE_000701"
     CDS             complement(14165..14398)
                     /locus_tag="ACFOAE_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
                     /protein_id="HFC6884230.1"
                     /translation="MKLTLMFREYCSLCHKMRDALKPFQNEYGFGLEVVDVDENPVLE
                     EKYNELVPVLLAGDEEICHWFLDEDRLKQFLER"
     gene            complement(14564..14764)
                     /locus_tag="ACFOAE_000702"
     CDS             complement(14564..14764)
                     /locus_tag="ACFOAE_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HFC6884231.1"
                     /translation="MFVCICNAVTDHQIKETIAAGATTMGDLQSQLGVASCCGCCGEL
                     AASFLTAHNAQPTVTAGINVQA"
     gene            complement(14936..15811)
                     /gene="xerD"
                     /locus_tag="ACFOAE_000703"
     CDS             complement(14936..15811)
                     /gene="xerD"
                     /locus_tag="ACFOAE_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFC6884232.1"
                     /translation="MEEGLIDRLLETLWLDRRLNQNTLNGYRRDLEKIARRLSQSGRM
                     LKDADEADLAAAVYVDGEQRSSQARALSACKRLYIWMEREGIRTDNPTRLLKPPKIDK
                     NIPTLITEQQISRLLAAPDTDTPHGLRDKALLELMYATGLRVSEAVGLNFGNVDLDRG
                     CITALGKGDKQRMVPMGQESAYWVGRYYTEARPALLKGRSCDALFVSQKKTGISRQLA
                     WMIVKEYAGRAGIGHISPHSLRHAFATHLVQHGLDLRVVQDMLGHADLNTTQIYTHVA
                     NVWLQGVVKEHHSRN"
     gene            complement(15863..16303)
                     /locus_tag="ACFOAE_000704"
     CDS             complement(15863..16303)
                     /locus_tag="ACFOAE_000704"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HFC6884233.1"
                     /translation="MDVKYEFTLPSSSGADFHSAEHLPLVVYFYPKDSTPGCTTEGLD
                     FNARLEQFEALGYTVVGISRDGVKAHQNFCAKQGFRFELLSDKDETVCRLFDVIKLKK
                     LYGKESLGIERSTFVLNKDGEIAHEWRRVKVAGHAQEVLETLSR"
     gene            16624..17562
                     /locus_tag="ACFOAE_000705"
     CDS             16624..17562
                     /locus_tag="ACFOAE_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFC6884234.1"
                     /translation="MSIHTLKRLPSSLLLGLCLSLPSAHLFADNDILGQFLEQNMLTS
                     SDPIEIFAESTIHPTNTQAITGGLILSSQSALVVNNKTGQILYQKNADRIMPIASISK
                     LMSAMVVLDANLDMNETVTITPDEIDRLKGTGSRLAIGTALTRKELLHLSLMSSENRA
                     THALGRTYPGGMGAFVAAMNRKAQSLGMYGSRFYEPTGLNFQNVSTAKDLSLMVNAAA
                     QYPQIRTNSTSNYASVQTKNGQQNYKNSNALVREGMWNIELQKTGYIREAGRSMVVKA
                     NIQNQPVTIVLLNSPTSATRVNDARKIESWMLQQRS"
     gene            17691..17984
                     /gene="hfq"
                     /locus_tag="ACFOAE_000706"
     CDS             17691..17984
                     /gene="hfq"
                     /locus_tag="ACFOAE_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HFC6884235.1"
                     /translation="MTAKGQMLQDPFLNALRKEHVPVSIYLVNGIKLQGQVESFDQYV
                     VLLRNTSVTQMVYKHAISTIVPARSVNLQHENRPQAAPTSTLVQVETVQQPAE"
     gene            18069..18635
                     /locus_tag="ACFOAE_000707"
     CDS             18069..18635
                     /locus_tag="ACFOAE_000707"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC6884236.1"
                     /translation="MLLQNILPFAHCLLRQALPEGGNALDGTAGNGHDTLFLAQTAGI
                     RGKVWAFDIQPQALNNTRCRLQEAGYSNVRLILDGHENLKQYIPKPLDAAIFNFGWLP
                     GGDKSLTTRTETSIAALSAALSLLKENGMLIAVLYPGHENGKQEAEAIEQWAKNLPQE
                     QFAVLRYSFTNRKNSPPYLLAFEKLPQK"
     gene            18689..19063
                     /locus_tag="ACFOAE_000708"
     CDS             18689..19063
                     /locus_tag="ACFOAE_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB2 family protein"
                     /protein_id="HFC6884237.1"
                     /translation="MQYLIVKYSHQIFVTITILVFNIRVFLLWKNPEKPLAGFWKALP
                     HLNDTMLLFTGLWLMKITHFSPFNAPWLGTKILLLLAYIALGMMMMRARPRSTKFYTV
                     YLLAMCCVACIVYLAKTKVLPF"
     gene            19073..19567
                     /gene="folK"
                     /locus_tag="ACFOAE_000709"
     CDS             19073..19567
                     /gene="folK"
                     /locus_tag="ACFOAE_000709"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HFC6884238.1"
                     /translation="MNNRHFAVIALGSNLENPAQQVRAALDTLSSHPDIRLKQASSLY
                     MTAPVGYDNQPDFINAVCTVSTTLDGIALLAELNRIEADFGRKRSFRNAPRTLDLDII
                     DFDGISSDDPRLTLPHPRAHERSFVIRPLAEILPDFVLGKHGKVAELSKRLGNQGIRL
                     LPDR"
     gene            complement(19695..20174)
                     /locus_tag="ACFOAE_000710"
     CDS             complement(19695..20174)
                     /locus_tag="ACFOAE_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HFC6884239.1"
                     /translation="MPESIFKQISLDILKLHRDSVYSLLATSGCNCQVHEAAYVNIDG
                     KYYIALSCEPEVGEVKTGILLIEDESRNLRLSWVGSARELDRKDSAYKRALSALSRKL
                     GRCKDRLHTAVQPFLLELVPEKGRFSVGDEEVWISRNDLVRALYPVGYSMRQAMLQI"
     gene            complement(20394..21131)
                     /gene="ubiE"
                     /locus_tag="ACFOAE_000711"
     CDS             complement(20394..21131)
                     /gene="ubiE"
                     /locus_tag="ACFOAE_000711"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HFC6884240.1"
                     /translation="MGGQKTHFGFSTVNEDEKAGKVAEVFHSVAKNYDIMNDVMSAGL
                     HRVWKHFTINTAHLKKGDKVLDIAGGTGDLSRGWAKRVGKEGEVWLTDINSSMLTVGR
                     DRLLNEGMILPVSLADAEKLPFPDNYFNLVSVAFGLRNMTHKDAALKEMYRVLKPGGT
                     LLVLEFSKIYKPLEGAYDFYSFKLLPVMGKLIAKDAESYQYLAESIRMHPDQETLKQM
                     MLDAGFDSVDYHNMSAGIVALHKGVKF"
     gene            complement(21174..21542)
                     /locus_tag="ACFOAE_000712"
     CDS             complement(21174..21542)
                     /locus_tag="ACFOAE_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF971 domain-containing protein"
                     /protein_id="HFC6884241.1"
                     /translation="MNNIPVEIRLLKNRTVLVLTYGDEPKNLPAEFLRVYSPSAEVRG
                     HGVGQDVLQTGKADVQIADLQPVGQYALKISFSDGHDSGLYDWAYLHRLAYGYDAMWQ
                     EYLDKLAAAGASRFEKQSDC"
     gene            21662..23275
                     /gene="mnmC"
                     /locus_tag="ACFOAE_000713"
                     /pseudo
     CDS             21662..23275
                     /gene="mnmC"
                     /locus_tag="ACFOAE_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214054.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016645 - oxidoreductase activity, acting
                     on the CH-NH group of donors [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
     gene            complement(23394..23511)
                     /locus_tag="ACFOAE_000714"
                     /pseudo
     CDS             complement(23394..23511)
                     /locus_tag="ACFOAE_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215773.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain protein"
BASE COUNT         6064 a         6850 c         5262 g         5445 t
ORIGIN      
        1 tcctgccgtg ttagcgtgta taatcaggca ttctatccga aattcacaac aggtcagcaa
       61 tatgtctttg aaaacagtag ccgttatcgg cgcaatggaa caagaaatcg agcttttgcg
      121 cgagatgatg gaaaatgtca aaaccgtctc tttcggcaga ttttccgcct atgaaggcga
      181 attggcggga aaacgcatgg tgcttgcatt gagcggcatc ggcaaggtca acgcggcggt
      241 tgcaacagct tggcttatcc atcaattcgc accggactgc gtcatcaaca ccggcagcgc
      301 gggcggtttg ggcaagggtt tgaaagtcgg cgatgtcgtg gtcggcacag aaatcgcgca
      361 ccacgatgtc gatgtaaccg cattcggcta tgtttgggga caagtgccgc aactgccggc
      421 aaggttcgct tcagacggca tattgattga aacggcaaaa cgggcggcgc ggacgtttga
      481 aggcgcggcg gtagaacaag ggctgattgt cagcggcgac cgcttcgtcc acagcagcga
      541 aggcgtggcg gaaatccgca agcacttccc cgaagttaag gcggtagaaa tggaagcggc
      601 ggcaatcgcc caaacctgtc atcagttgga aacgcctttc gtcatcatcc gcgcggtttc
      661 cgattcggca gacgaaaagg cagacatcag ctttgacgag ttcttgaaaa cggcggcggc
      721 aaattccgca aaaatggtgg cagaaatcgt caaatcttta taaaaccttt atcaaatcat
      781 gccaaaacag cggttttccg ttagaatatc gggctatttc cacgttgcgc ccgatatttg
      841 gacgtaccgc tgtttgttca gacggcattt ctaaaaccta ccgttcagca ttaaaaacaa
      901 ctcaatgaaa aatatccgaa atttctccat cattgcccac atcgaccacg gcaaatcgac
      961 gcttgccgac cgcttcatcc aatattgcgg cggtttggat ttgcgcgaaa tgagtacgca
     1021 ggtactcgat tccatggaca tcgaaaaaga gcgcggcatt accattaaag cgcaaaccgc
     1081 cgcgctcaac tataaagcac gcgacgggca ggtgtatcaa ctcaacctga ttgacacgcc
     1141 gggacacgtc gacttctctt acgaagtctc tcgttcgctc tctgcctgcg aaggcgcgct
     1201 tttggtcgtt gacgcgtcgc agggcgtgga agcgcaaact gtggcgaact gctataccgc
     1261 gattgatttg ggcgtggagg ttgtgcctgt tttaaacaaa atcgacctgc ccgccgccga
     1321 ccccgaacgc gtggaacaag aaatcgaaga cattatcggc atcgatgccg tcggtgcggt
     1381 gcaatgttcc gccaaaagcg gcatcggcgt ggaagacgtt ttagaagaaa tcgttgccaa
     1441 aatccctgcg ccgaccggcg acgaaaacgc gccgctgcaa gccgtgatcg tcgattcgtg
     1501 gtttgacaac tatgtcggcg tggtcatgct gattcgagtg aaaaacggca ccatcaaact
     1561 gaaagacaaa gtgcgcttta tgagcaccaa ggcggaaacg caggtcgagc agctgggcgt
     1621 attcacacca aaatcagttc aaaaacaaga actcaaagcc ggcgaagtgg gctttttgat
     1681 tactggcgta aaagaattgg gtcaggcgaa agttggcgat acggttacac tggttgccaa
     1741 ccctgccact gagccgctgc ccggcttcca agaagtacaa agccaagtat tcgccggact
     1801 ttatcccgtg gaaagccacg actacgaagc cttgcgcgac gctttggaaa aattgcagct
     1861 taacgacgct tcgttgaaat tcgagcctga agtttcccag gcattgggct tcggcttccg
     1921 ttgcggcttc ttgggtctgc tgcacttgga aatcgtgcag gaacgtttgg agcgcgagtt
     1981 cgacatggac ttgattacca ccgcgccgac ggtggtttac gaagtcgtgt tgaaaaacgg
     2041 tgagaaaatc gaagttgaaa acccgtccaa actgcccgac atcggcagca tcgaaaccat
     2101 actcgagccg attattaccg cgaccatcct cgtgccgcag gaatacgtcg gcaacgtcat
     2161 gactttgtgt aaccaaaagc gcggcgttca ggtcaatatg caatatatgg gccgccaagt
     2221 catgctgact tacgatttgc ccatgaacga agtcgtcatg gacttcttcg acaaactcaa
     2281 atccacttcg cgcggttatg cttcgttgga ctaccatttc aaagagttcc aaccgtctga
     2341 tttgattaag ctggatatca tggtcaacgg cgaaaaagtc gatgccttaa gcctgattgt
     2401 gcaccgtcaa agcgcggttc accgaggccg cgagctggca tcgaaaatgc gcgagctgat
     2461 tccgcgccaa atgttcgaca ttgccgtcca agccgccatc ggcagccaga ttatcgcccg
     2521 cgaaaacgtc aaagcactgc gtaaaaacgt cttggcgaaa tgttacggcg gcgatattac
     2581 gcgtaagaaa aaactgcttg aaaaacaaaa ggcaggtaaa cgccgtataa aacaagtggg
     2641 caatgtggaa atcccgcaaa gcgcgttctt ggcgattttg caggtgagcg acaaataata
     2701 tttcggcaca tagggcggcg cgtcgggaac acctctcaaa ccgccctgat ttcaggggca
     2761 cgcgcccgca aacaaatttt gcaatttgcc gccttaaaac ggttgcacgg ccgggcgggt
     2821 ttttaaccgt tgaggaacaa caatgaacac aatgctaatg tcgggcgcgg ctgccgcgct
     2881 gcttgccggc atcatccttt atttcaaaag cgacaagaag cggcaggaaa acggtgaatg
     2941 gagttccggc ctcgaatacg cctatatcct gacggcggtc ggcgtgtttg ccgctttgtc
     3001 cctgtttatg agctttgccg ccgttttcct gattttcgtt gtattgtgcg gtacggcttg
     3061 ggcggtatac aaataccgcc tgaagactca tcccgaaatc tcggaaagca gccacttcgg
     3121 cgattatttc ggcagtttct tccctaccgt tttggtattg ttcctcatcc ggtcgtttat
     3181 tgccgaaccg ttccaaatcc cgtccagctc gatgcgcccg ggcctgatta agggcgattt
     3241 cattttggtc ggcaaatttt cctacggtct gcgcgtaccc gttttaaaca atatatttat
     3301 tcctacaggc aaaatcgaac gaggcgatgt cgttgttttt aattatcctc tgcagccgga
     3361 gatgacctac atcaagcgta ttgtcggcat tccgggcgat gtggtcgaat atcgggataa
     3421 gattttgacg gtaaatggca aacccacttc cgatattcct aacggcacat accgttatcc
     3481 cgacgacacc gacccatccg aaatccacaa tacggatatg ttccacagcg gtttggacgg
     3541 caaatccttc aatattctga aaaaagaagg acagcctgcc gtttccctgc ccgtattggg
     3601 caaatatacc tccgatatta tgtctgaaaa cggatattcc atagagcaaa gcggtttgga
     3661 acactgccaa tatgccgacg acggcagcgg tttcgtgtgc aaagttcccg aaggacgcta
     3721 tttcgctatg ggcgacaacc gcgacaacag tgccgattcg cgctactggg gatttgtgga
     3781 tgacaagctg gttgtcggca aggcaatgtt cattttgatg aacttcggcg atttcggcag
     3841 ggccggtacg gcaatccgtt aggccaggaa gccaagaatg ccgtctgaaa atagtttcag
     3901 acggcatttg ctattcctca cttttgcagg cggatctaac gttgtcggat tttcctacct
     3961 atagtgaatt aaatttaaat caggacaagg cggcgagccg cagacagtac aaatagtacg
     4021 gcaaggcgag ccaacgctgt accggtttaa atttaattca ctatatcagt ccggtaacgc
     4081 aggttttgca cggaaaactg ccaatactgc cttgatggaa tcaatattaa gactgctgtt
     4141 tcagcgaacc gaggtaaatt gccgaaagcg tcagcgccac ccctgcccac tgcacgcctt
     4201 caatcggttt gcccaacccg aaataatcga tgaacagggc ggcaaccggt tcggacaaaa
     4261 gcagcagccc cgtcagcgac agcgaaagca gcggaatcgc ataggcaacc atcgcccacg
     4321 cgaagcactg catcaccacg ccgtacacaa gcaccaaacc cgcatctttc caagtcgtcg
     4381 gataaagcac gccgccatcc atcagcaatg ccggaacaac cagcgatacc gcgccgccca
     4441 aactcaaaat catcattgaa gggaaaagcg ccaccggctc gatttcatgg gttttgcgga
     4501 cgaacaccat cgacagggcg agcatcagtc ccgataccaa accgctggcg aatccccaaa
     4561 ccgcattacc gttgtagccg aattccgcac cggcaatcat cgccacgccg gcaactgccg
     4621 atattaagcc tgcctttttc agcccgctca aacgctcgcc gaaaaagaaa acaccgattg
     4681 ccgacaagaa aaagatttgc aggctgttga gcagggtgga aatacccggc ccgaccgcgt
     4741 gtatgctttc gtgccacaac gccaaatcga aagcgagaaa cacgcccgcc gtcagggcat
     4801 atcggacggt tttcctgttt tttgggaatt tttgcccgaa aaaccgtgct aaaaaccaaa
     4861 atacgaacac cgaaatcagc aaccgccaaa atgcgattgc atacgaaccg acggggacgg
     4921 atctgacaat cagactgccc agaccgaaca ccacgcaacc cagcaccagc aatggtgcgg
     4981 catatttttt gccgttaccg accacaatat cccctccctt ccccatacgg ctgccgcgcc
     5041 gacggcaaga atgccgccat tccgaaaata tgccgtctga agcccaaagc cccggctgca
     5101 cccggacaaa cggctgattt tacgggcagg caggctattt tccgttgggg caaaaaaccg
     5161 tcctgccgga taaaacccga atatagtgga ttaacaaaaa ccagtacagc gttgcctcgc
     5221 cttagctcaa agagaacgat tctctaaggt gctgaagcac caagtgaatc ggttccgtac
     5281 tatagtggat taacaaaaac cagtacagcg ttgcctcgcc ttgccgtact atctgtactg
     5341 tctgcggctt cattgccttg tcctgatttt tgttaatcca ctatatttgt actgtctgcg
     5401 gcttcgttgc cttgtcctga tttttgttaa tccactataa aaaatatttc cctcaagcga
     5461 tgcagcgaca ccaacacctg attaaaacac aaccggcgtt ttcggcatat acgcaaaaac
     5521 gcattttccg gcacggcgtt acaccgatac cgaaaaatgc gtctgaatgt ttcgacaatc
     5581 cgattaaagc attatgccaa atctgcaaaa agtggcgtag agagatagcg ttcgccataa
     5641 gaaggcagca gcacgactat cagcttgcct tcgttttcag gctgtttggc aagctgcaac
     5701 gcactccaaa ccgccgcacc ggaagaaata cccaccaaaa tgccttcttt ttccgctatt
     5761 gcgcgggcgg tttcaaaagc cgcttcgttc gacactttgg taatgctgtc gtaaattttg
     5821 gtattcaaaa cggtcggaat aaagcctgcg ccgatgcctt gaatcgggtg cgggcctttt
     5881 tcgccgccgc tcaatacggg tgaagcttca ggctcgacgg caaccacttt aacttcgggt
     5941 ttgtattttt tcaacacttc gcccacgccg gtaatcgtac cgcccgtgcc gacgccggca
     6001 acgaagacat cgactttgcc gtccgtatcc cgccaaattt cctcggcggt tgttttgcgg
     6061 tggacttcgg ggtttgcctc attgtcgaac tggcgcggca taaaataagt gtcgggatgc
     6121 gcgtccacca aggatttcgc tttggcaatc gcgcccgcca taccttcggc ggcaggggtc
     6181 agaatcagct ccgcaccaaa cgcgcgcaac agcattttgc gctccttact catgctttcc
     6241 ggcatggtaa tcgccagctt gtagccgcgt gcggcacata ccattgccaa accgacaccc
     6301 gtattgccgc tggttgcttc gacaatgacg gtgtttttgt tgattttgcc cgctttttcg
     6361 gcaccctcga tcattgcttc ggcaatgcgg tctttgacgc tgctgcctgg attgaaaaat
     6421 tccagtttca cggcaacctc cgccttcaaa ccttcggtca gacggttcag tttgaccaaa
     6481 ggcgtgttgc cgattagttc ggtgatgctg tttgcaattt tcatcttctg ctcctgaata
     6541 ataaggtttc gacagtaagg cgcaatcccc ataggcatcc tgtccgattg caggggattt
     6601 gcgccgaaac ataaacaaat ttcggatatg gctttatcct aaacctatgc cgcctaaaaa
     6661 accaatatcc aaaatttctt tctttataac tttttgttcc gatacggccg caccgtatta
     6721 tcttccaatt tctgaaagca gcagcaccag taccgagacc tgcatcaacg ctgccgtcaa
     6781 cccgccgagt cgcagctgcg agccgccgaa cgttgacggc ggctgccggt ctataccgca
     6841 gcggtggaca taggcaaccg ccatcagcac aaactgcaac acgaaccaat aaaccggctt
     6901 cagcgcataa agtttgagca gtgccgcaaa cacaaacact tgaaccgttc ccgaaaagca
     6961 ataatgcacc aacgcacata ttccgacaaa agcaagcgtc atcgatacat tactgacggc
     7021 aaaaagcccg agcagcggat gttcggggtc tgcctgccat ccgtttccat ctgttttccg
     7081 gttccaatgc ccgatgaaaa aaaatatgct gcccaaagtc aggtaaaaat gggggatgaa
     7141 caagggcgcg gcgcgggtca ttccccatat gccgggcatc agctttgccc ccaaaaccga
     7201 tatgccgagc cacagcgcaa tactcgccca aaaccattgc aacattcctg cgcggaatat
     7261 cagaaacaga aaaaccgccg catacagtaa ggcagacaaa aaatccaaat gcagcaaaat
     7321 catgaatacg ccaactcgcc ttcaaacacg gtttccgcag ggccggtcat catcacatcg
     7381 ccgccgcagg cccattcgat atataaagtt ccgcccggca aaatcacctc taccgttttc
     7441 ccttcatcca acaaccccag acggataccc gccaccacag ccgcacacgc gcccgtaccg
     7501 cacgcttggg tttcgcccac gccgcgctcg aacacgcgca aacgaatcgc ggttcggccg
     7561 acaacctgca taaagccgac attgacgcgt tcgggaaact gcctgtgcgg ttcgataagc
     7621 gaaccggttt cgcgcaccgg cgcgcattcc acgtcatcga ccacaatcac cgcatgggga
     7681 ttgcccatat tgacgcagct gacaggctga atgccggatt cgagatgcac cccgtaaata
     7741 caggcatcat ccccctcgcc cgattcgggg acaaacggta tttcagacgg cataaacttc
     7801 ggtttgccca tattgaccgt aaccataccg ttatcggaca atttcggaaa aataacgcca
     7861 tttgccgttt caacacaaat ttctttctta tcggtcaaac ccttgtctgc aacaaaacgg
     7921 gcaaaacaac gcgctccgtt gccgcattgc ccgacctcgc tgccgtcggc attgaaaata
     7981 cggtaacgga aatccacgcc ttcggtttcc gaacgcccga ccaccaaaag ctggtcgaag
     8041 cccacgcccc ggaaacggtc cgcccatgcc gcaatcggcg cgtcctcggg ggtaaaatcc
     8101 tgactgaccg cgtcaatcac cataaaatcg ttgcccaaac cgtgcatttt ggtaaatttc
     8161 aaagtgttca tattgttccg aaatcccgta tcgtctgttg cttccgaatc cgaaatcccc
     8221 cgcaccgaag ggaaatgctt ccatctcccg ccgtcgggag attaaaataa gcattatact
     8281 gtttgttacc ccttacaaga aacacaatgt cccgcctgtt cctgctgctt ttcccttggg
     8341 caatccttgc cgcctgcacc cgaaacatac cggcaaaccc ggccgtttca aattgcgcgc
     8401 atcttcaaaa ccgcaccatc ctgtattttg acgcacacgg caaacccgcc gacgacgcag
     8461 taaagggcgg attttacaaa attatcgaaa tacagggtgc aaaccgcatc cttattcaag
     8521 actttaacag cacgggcaat gccctcggcg gattctatgt gccggactgc cggaaatcat
     8581 ccctttcagc gaaaaatatc tgacttcaaa ctgcctatga accacgacat cactttcctc
     8641 accctgttcc tactcggttt cttcggcgga acgcactgca tcggtatgtg cggcggatta
     8701 agcagcgcgt ttgcgctcca actccccccg catatcaacc gcttttggct gatcctgctg
     8761 cttaacacag gacgggtaag cagctatacg gcaatcggcc tgatactcgg attaatcgga
     8821 caggtcggcg tttcactcga ccaaacccgc gtgctgcaga atattttata cacggccgcc
     8881 aacctcctgc tgctcttttt aggcttatac ttgagcggta tttcttcctt ggcggcaaaa
     8941 atcgagaaaa tcggcaaacc gatatggcgg aacctgaacc cgatactcaa ccggctgtta
     9001 cccataaaat ccatacccgc ctgccttgcg gtcggaatat tatggggctg gctgccgtgc
     9061 ggactggttt acagcgcgtc gctttacgcg ctgggaagcg gtagtgcggc aacgggcggg
     9121 ttatatatgc ttgcctttgc actgggtacg ctgcccaatc ttttggcaat cggcattttt
     9181 tccctgcaac tgaaaaaaat catgcaaaac cgatatatcc gcctgtgtac gggattatcc
     9241 gtatcattat gggcattatg gaaacttgcc gtcctgtggc tgtaagcccc attcattccc
     9301 gatacccgta aaaaataccg tctgaaacct gttcagacgg cactttcacc ctaagcgtta
     9361 ctcggcggca ttttcctcac gggcaggcgc gtccagcagg gctttgatgg acagacggac
     9421 acggcctctg tcgtccactt ccaatgcttt cacgttcacc acctgaccga cttgcaggta
     9481 gtcgccgaca ttgcgtacgc gctcgtgggc gatttggctg atgtgtacca aaccgtcttt
     9541 gcccggcatc acactgacaa tcgcgccgac attgctgtcg aggattttca ccacagtgcc
     9601 ttcgtacact ttgcccactt ccacttcggc agtaatctgc tcgatgcgtt ttttcgccgc
     9661 atcgccggct tcttgagtgg ttgcggcaat ggtaatcgta ccgtcttcgg caatattgat
     9721 ttccgtaccg gtttcagcgg taatcgcacg gatggtttca ccgcctttac cgataacttc
     9781 gcggattttg tcttggttga ttttcatcgt gaacaagcgt ggcgcgtgtg cggacagctc
     9841 ttgcgggccc gcaacggcgg ctttcatctg atccaagatg tgcagacgcg cttctttggc
     9901 ctgcgccaaa gcgatttgca taatctcttt ggtaatgcct tggattttga tgtccatttg
     9961 cagcgcggta acgccttcgg tcgtaccagc cactttaaag tccatatcgc ccaagtggtc
    10021 ttcgtcgccc aaaatgtcgg tcaggacggc aaatttgttg ccttccagaa tcagacccat
    10081 cgcgataccg gcaacgtgtg ctttcaaagg cacgccggcg gacagcaggc tcaagcagcc
    10141 gccgcagacg gaagccatag aggaagagcc gttggattcg gtaatttcgg agaccacgcg
    10201 catggtgtag ctgaaatctt caggtttcgg caatacggcc aacaatgcac gtttagccaa
    10261 acggccgtga ccgatttcac gacgttttgg cgcacctacg cgacccactt cgccggtaga
    10321 gtatggagga aagttgtagt gcagcatgaa gcggtcggtg tattcaccgg acagcgcatc
    10381 aatgatttgc tcgtcgcgtg aagtacccaa agttgcaacc gccaaagctt gagtttcgcc
    10441 acgggtaaac aatgcagaac cgtgcgtgcg cggcaatacg ccggtttgaa tgttcagcgg
    10501 acgaacagtg cgggtgtcgc gaccatcaat acgcggttgg ccgtctaaaa tttggctgcg
    10561 gacaacatcg gcttccaagt gtttgaaaat gcctttgatt tcgttggctg ccaaagtgtc
    10621 ggtttcctcg gtaatcaagg cttcttttac agcactccaa gcttcgtcca atttggcaga
    10681 acgcgcttgt ttttgacgga ttttgaatgc ttctttaatg gtttcaccgg caatttcgcg
    10741 tacttttgca accaattctt cattggtttc aggtgctttc caatcccaaa gttccggatt
    10801 gacttcgtcg gcaaattcat tgattgcatt gatggcaacc tgcatttgat cgtggccgta
    10861 aaccaccgcg cccagcatca cgtcttcggg caggattttg gcttcggatt ccaccatcaa
    10921 cacggctttt gaagtaccgg cgaccaccaa gtccaattgc gatttcgcca attcggcttt
    10981 agtcgggttc aaaacgtaca cgccgtttat ataacccacg cgtgccgcac caatcggacc
    11041 ggcaaacggt acgccgctca acaccagcgc ggcagacgcg cccaacattg caggaatgtc
    11101 ggaatcgatt tcgggatcga cggacacgac catcgctacg atttggatgt cgtggtagaa
    11161 accttcgggg aacagcggac gaatcgggcg gtcgatcaga cggctggtca ggatttcttt
    11221 ttcgctttgt ttgccttcgc gtttgaagaa accgccgggg attttacctg cggcgtaagt
    11281 gcgttccaaa taatcgacgg tcagggggaa gaagtcttgg ccttctttca cttctttgtt
    11341 ggtggtaacg gcaaccaaaa ccacggtgtc gcccatagag actttaacgg cagcggcggc
    11401 ttggcgggca atttcaccgg tttccaaagt aacggtctga ttaccgtatt ggaaggtctt
    11461 aacgtgtttg tcgaacatca ttgttccttt caaaataccg cactgctaaa acactaataa
    11521 tgcacactaa aatccgaatg tgcatagtta gggtttcaga ccgtgcagca ggttgtaaac
    11581 aagctttcag acgacatttc ggacgctgaa agcaattccg gattataaag gcaaccatcc
    11641 ttaaaatcca gtattgatac aataaaaagg ccgtctgaac catatttctt tcagacggcc
    11701 ttcaaactta aaaatcaatc ctgagtcagc aaagtcaatg cttcccgata cttctcgaca
    11761 gttttctgaa tcacatcggc aggcactttc ggcgcagggg cttttttgtt ccaaccgctt
    11821 tgttccagcc agtcgcggac gaattgtttg tcaaaagacg gcggattggt gccgacttca
    11881 tattgatccg ccggccagaa gcggctcgaa tcgggagtca atacctcatc catcagcgtc
    11941 agcgtaccgt ttgtatccaa accgaattca aatttggtat cgcaaataat aataccgcgc
    12001 gatttggcat attccgccgc ttcggtgtaa agccgaaccg ccttggcgcg cacttcttcc
    12061 gccaattctt tgccgataat gcgtccgcat tcttcaaagc tgatgttttc atcgtgatcg
    12121 ccgactgcgg ctttggtcga tggcgtaaaa atcacttcag gcagttgttg cgcttcctgc
    12181 ataccttcgg gcagccgaat accgcaaacc gagccggttt tttgataatc tttccaaccg
    12241 ctgcctgcca gataaccgcg cacaatcgcc tctactttca ccggagtgag ctttttagcc
    12301 acgacggcgc gtttttctaa aactttggct tcgttttcag gcaaaacatc gtaaaccgtt
    12361 tgaccggtaa agtggttggg cataatatgc gccagttttt taaaccaaaa attggaaatc
    12421 tgcgtcagaa tctccccttt gctcggaatc gggtcgtcca aaatcacatc aaacgcggac
    12481 aggcggtcgg aagcgaccat cagcatacgt ttatcgtcga tttcatataa atcgcgcact
    12541 tttccagaat agatctttac caaaccaatc tcactcattt cgccccccct gaaaatatct
    12601 tgaaaatacc gacccgacac ccgacaggtt tgaatcacaa accgatattc taaccgaagt
    12661 cggcgcaaaa caatacccat ggcacaaaaa gccaacccgt caaccgtcgg caaagttttg
    12721 gcactataat accgacagca agtcctacaa tacactttca ccaaaggaaa tacctcatga
    12781 gaatcctatt gacaggctcg aaaagccaac tggcacgctg cctgcgcgac cgtcttccgg
    12841 aagactggga aaccattgcg acggattccg catccctaga cattaccgat gccgatgccg
    12901 tctgcaacat ggtcaaaagt ttccaacccg acgccattgt caacacggct gcctatactg
    12961 ccgtcgacaa agcggaaggc gatgcggcag cggcatttgc cgtcaatgct tccgccgttt
    13021 acaaccttgc cttggcagca catcgcgccc atgcccgatt cgtccacatt tcgactgact
    13081 atgtctttga tggtaaaagt aaaaaacctt accaggaaag cgactttacc aaccctgcca
    13141 atgtatacgg acaatccaaa accgcaggcg agctgctcgc actgtctgcc aatcccgaca
    13201 gccttatcct gcggacttct tggctgttta gcgaatacgg ggacaacttt gtccgcacga
    13261 tgctgaacct tgcgcgggaa cgttccccgc tgtccgccgt ccacaaccaa atcggctgcc
    13321 cgacctatgc cggcgattta gctgccgcca tcatccgcct tttgcagcaa acgtcgcccg
    13381 tgcgcggcat ttaccactac gccggcggca aatccgtatc ctggtacgaa tttgcccaac
    13441 atattttcca agcggcatcg caacagcaga catccttccc cgttcccgaa ttgactgccg
    13501 tttcagacaa ggaatatccg accgccgccc ccaggcccgc atacagcatt ttggactgcc
    13561 gcaaaatcga aaacgacttc agcatcaaac cgtcagactg gcaaaaagcc cttgcacagg
    13621 tcgtttccaa gctgctctga tgccgcccgc ctctccgttt ccgccgtcaa gcaccgcctt
    13681 ggcggttttc ttatatagtg gattaacaaa aaccagtacg gcgttgcctc gccttagctc
    13741 aaagagaacg attctctaag gtgctgaagc accaagtgaa tcggttccgt actatttgta
    13801 ctgtctgcgg cttcgtcgcc ttgtcctgat ttttgttaat ccactataaa atctaccgat
    13861 tacacaaaca catatcatct ttacacaatc atgcttccat caacagtaaa acatgatatg
    13921 attgccaaca ataacatctc acaataaatt ttctaatttt tattgaaaaa atcaataaat
    13981 aagaattctc ccaaccgaca aataaaataa agaaagggtt aatatgcaac atcgaagaag
    14041 actagcaatt taccaagcat ccaaacgtgc ttcctttacc ggcaggtcat ccgccccgca
    14101 aaaacgtaaa gaacgttgat ttgaaaaaaa tgccgcctga agtcctgctt cagacggcat
    14161 ttttttaccg ttcgagaaac tgtttcaacc tgtcctcatc caaaaaccag tggcagattt
    14221 cctcatctcc cgccaacaaa acgggaacca gctcattgta tttttcttcc aaaacaggat
    14281 tttcatccac atcgaccact tccagcccga acccgtattc attttgaaaa ggtttgagtg
    14341 catcgcgcat tttgtggcac aagctgcaat attcacgaaa catcaaggtc aatttcatcc
    14401 gcgtttcctt atctgtcaat ttgcacacgc caaagcctta gacgcagcag aatcatggtc
    14461 tatttgggaa aaaacaatgt tttcaaggaa gatgatactc aagtcctgcc aaaaacagca
    14521 aaaatgccgt ctgaacagtt cagacggcat ttccaaaacc gttttacgct tgaacgttga
    14581 tacccgccgt aaccgtcggt tgcgcattgt gcgccgtcag aaacgaagcg gcaagctccc
    14641 cgcagcagcc gcagcagctc gctacgccca attgcgactg caaatcgccc attgtggtcg
    14701 cgccggcggc gatggtttcc ttgatttgat ggtcggtaac ggcattgcag atgcagacaa
    14761 acattttgtg ctccgtgtgt tctcaaacta tcgtaccgat agcggctttt attatcgtat
    14821 gcaaatataa ataaaaacgg ttcgcattgc aaggtcggca tacacggttt gtcttggtaa
    14881 ttttttatca agtttgcatt ttcgattgat ttcttattaa accgaagcag aagcctcagt
    14941 ttcgggaatg gtgttccttc actacaccct gcaaccatac attggcaaca tgggtataaa
    15001 tctgcgtcgt attcaaatcg gcatgtccca acatatcctg aaccacgcgc aaatccaatc
    15061 cgtgctgcac caagtgcgtg gcgaaggcat ggcgcaggct gtgcgggctg atgtgcccga
    15121 tgcctgccct acctgcatat tctttgacaa tcatccatgc caactgacgg gaaatacctg
    15181 tttttttctg actgacaaac aaggcatcgc aactcctgcc cttcaacaag gccggacgcg
    15241 cctccgtgta atagcgtccc acccaatacg ccgattcctg ccccatcggg accatcctct
    15301 gcttgtcgcc cttgcccagc gcggtaatac agcccctgtc caaatccaca ttgccgaagt
    15361 tcagcccgac cgcctcgctg acgcgcaagc cggtcgcgta cattaattca agcagggcct
    15421 tgtcccgcaa accgtgcggc gtgtcggtat ccggtgcggc aagcagtcgg gaaatctgct
    15481 gttctgtaat cagggtcgga atattcttgt cgattttggg cggtttcagc aaacgggtgg
    15541 gattgtccgt ccttatgcct tcacgctcca tccatatata caggcgtttg catgccgata
    15601 atgcgcgcgc ctgcgaactc cgttgctctc cgtcaacata aaccgccgcc gccaaatccg
    15661 cttcgtccgc atccttcagc attctgcccg attgggacag gcggcgggcg attttttcca
    15721 aatcgcgccg gtaaccgttt aaagtattct gattgagccg cctgtccaac cacagcgttt
    15781 caagcagcct gtcgatcaaa ccttcttcca taccgttcca aacaaatgcc gtctgaatct
    15841 tcttcagacg gcatggttca cattatcggg aaagcgtttc caatacttcc tgcgcgtgac
    15901 ccgccacttt gactctccgc cattcatggg cgatttctcc atccttattc aagacgaacg
    15961 tactgcgctc gatacctaac gactctttcc cgtacagttt cttcaatttg atgacatcaa
    16021 acaggcggca cactgtttca tccttgtcgc tcaacagctc gaaccggaaa ccctgcttgg
    16081 cgcaaaaatt ctgatgcgcc tttacgccgt cgcgggaaat accgaccacg gtataaccca
    16141 atgcctcaaa ctgttccaaa cgcgcattga aatccaagcc ttccgtcgta cagccaggcg
    16201 tactgtcttt cggataaaaa tacacgacca aaggcagatg ttctgccgaa tgaaaatccg
    16261 caccgctgct cgaaggcagg gtaaattcat atttcacatc catagtccta ctcccgatat
    16321 tcccattatt caaaacggca cgcagaggca ccgccgcaat tgccaaacca accccgattc
    16381 taccgcccca aaggacaagg attcaactgc cggaaacatc caaaccgaca cacgacggca
    16441 tgaaaaatat ccatgtcaaa ccacaaaata tgttccgatt taaaaacaga atgttataaa
    16501 acccaatccc caaaacacaa caagaccgcc cgcctacggg cagtctcctg tcagacgaca
    16561 tactttacag atggctgttt tttcaacaaa ataacgccaa tactcaaaaa tatggaatca
    16621 aaaatgtcca tccatactct gaaacgcctg ccctcatcgc tgctgctcgg tctctgcctt
    16681 tccctgccgt cagcccacct ttttgccgac aacgacattt tagggcaatt tttagaacag
    16741 aacatgctta cctcctccga tccgatagaa atattcgccg aaagcacgat acaccccacc
    16801 aacacccaag ccattacagg cggtctgatt ctctcctcac agtctgccct ggtcgtcaac
    16861 aacaaaaccg gacagatact gtatcagaaa aacgccgaca ggattatgcc catcgcctcc
    16921 atttccaaac tgatgagcgc gatggtcgtt ttggatgcaa acttggacat gaacgaaacc
    16981 gttaccatca cgcccgacga aatcgaccgc ctcaaaggga ccggcagccg tcttgccata
    17041 ggtacggcac ttacacgcaa agaactgctg cacctgagcc tgatgagcag cgaaaaccgc
    17101 gccacccatg cattgggcag aacctacccc ggcggcatgg gcgcatttgt cgccgccatg
    17161 aaccgcaaag cccaaagcct gggcatgtac ggcagccgct tttacgaacc gaccggactc
    17221 aacttccaaa acgtttccac cgccaaagac ctgagcctta tggtcaacgc cgccgcccaa
    17281 tatccgcaaa tccgcaccaa ctcgacttcc aactacgcct cggtacagac caaaaacggg
    17341 cagcagaact acaaaaactc caatgccctg gtcagagaag gcatgtggaa catcgaattg
    17401 cagaaaaccg gctacatacg cgaagcaggc aggtctatgg ttgtcaaagc caacattcaa
    17461 aatcaacccg ttaccatcgt attgctgaac tcgcccacat ccgccacacg cgtcaacgac
    17521 gcccgcaaaa tcgaatcgtg gatgctgcag caacgctcct gacatacaaa tgcccggcgg
    17581 aaaaccgccc aaacacaaaa aaaattggta atttttccta ttcaaggcta caattcgaca
    17641 cgcacagggc atctgcccga tttcacaatc ataatagcgg agttaaaaat atgacagcta
    17701 aaggacaaat gttgcaagat cccttcctga acgccctgcg taaagagcat gttccggttt
    17761 cgatttactt agttaacggt atcaaattgc aaggtcaggt tgagtctttc gatcaatacg
    17821 ttgttctcct gagaaacact tccgtcaccc aaatggttta caaacacgcc atttccacca
    17881 tcgtaccggc acgctccgtc aacctacaac atgaaaacag accccaagcc gcaccgactt
    17941 cgaccctcgt ccaagtggaa accgtccagc agcctgccga ataatccgca cgaagcatga
    18001 cgtgtcatat ctttcaatac cttaccggac aacggtaagg tatttttatt ttcagacagc
    18061 atttaaaaat gttattgcaa aacatccttc cattcgccca ttgccttttg cggcaggcac
    18121 ttcccgaagg tggcaatgct ttggacggca ccgccggcaa cggacacgac acccttttcc
    18181 tcgcacaaac cgcaggcatc cgggggaaag tgtgggcatt cgacatccag ccgcaagccc
    18241 tgaacaacac ccgatgccgt ctgcaggaag caggttacag caatgtacgg ctcatcttgg
    18301 acggacatga aaacctgaag caatatattc caaagccgct ggatgcagcc attttcaatt
    18361 tcggctggct gcccggcggg gacaaaagcc ttaccacccg cacggaaacc agcattgccg
    18421 ccctttccgc cgccctatcc ctactgaaag aaaacggtat gcttattgcc gtcctctacc
    18481 ccgggcacga aaacggcaaa caggaggcag aagcaatcga acaatgggca aaaaacctgc
    18541 ctcaagaaca gtttgccgtt ctgcgttaca gctttaccaa ccggaaaaac agcccaccct
    18601 atcttttggc atttgaaaaa ctgcctcaaa aataactgtt tgcggtaaaa taagccgatt
    18661 ctaaccctta ttttgatacg agccgaccat gcagtatctg attgtcaaat acagccatca
    18721 aatcttcgtt accatcacca ttttggtatt caacatccgt gttttcctac tttggaaaaa
    18781 tccagaaaag cccttggcgg gcttttggaa ggcactgccc caccttaacg acaccatgct
    18841 gctgtttacg ggattgtggc tgatgaaaat tacccatttc tccccgttca acgcgccttg
    18901 gctcggtaca aaaatcctgc ttctgctcgc ctatatcgca ttgggtatga tgatgatgcg
    18961 cgcccgtccg cgttcgacca agttctacac cgtttacctg ctcgccatgt gttgcgtcgc
    19021 ctgcatcgtt taccttgcca aaaccaaagt cctgcctttc tgaaacaccg ttatgaacaa
    19081 cagacatttt gccgtcatcg ccctgggcag taatcttgaa aaccctgccc aacaggtacg
    19141 cgccgcattg gacacgctgt cgtcccatcc tgacatccgt cttaaacagg cttcctcact
    19201 gtatatgacc gcccccgtcg gttacgacaa tcagcccgat ttcatcaatg ccgtctgcac
    19261 cgtttccacc accttggacg gcattgccct gcttgccgaa ctcaaccgta tcgaagccga
    19321 tttcgggcgc aaacgcagtt tccgaaacgc gccgcgcaca ttggatttgg acattatcga
    19381 ctttgacggc atctccagcg acgacccccg cctcaccctg ccgcatccgc gcgcgcacga
    19441 acgcagtttc gtcatccgcc ctttggcaga aatcctccct gattttgttt taggaaaaca
    19501 cggaaaggtt gccgaattgt caaaacggct gggcaatcaa ggtatccgtc ttttacccga
    19561 caggtaattc cgcacgcgga tgccgtctga atgccggttt cagacggcat ttttaccctg
    19621 ccgccaatct gtacgcaaaa aaaatcgccc cttgaaaaag gggcgcaaaa ggaacacaaa
    19681 ccactaccaa aactttaaat ctgcaacatt gcctgccgca tactgtatcc gacaggatat
    19741 aaagccctca ctaaatcgtt tcgagaaatc caaacttctt catcgccgac agaaaatctg
    19801 cctttctccg gcaccagctc caacaaaaac ggttgaaccg ccgtatgcag cctgtcctta
    19861 caccgcccca gctttctaga caacgcggac agggcgcgtt tgtaggcact atccttgcgg
    19921 tcaagctccc gcgcactgcc gacccagctc aaacgaaggt tgcggctttc atcctcaatc
    19981 agcaaaatgc ctgttttgac ttcccccacc tcgggctcac atgaaagcgc aatataatat
    20041 ttgccgtcga tgttgacata cgccgcttca tgcacctgac agttgcagcc ggaagtggca
    20101 agcagcgaat aaacagagtc ccgatgcagt ttcaaaatat caagggaaat ctgtttgaaa
    20161 atactttccg gcatttttcc ctcctttcgt ctgctgcgtt gtttactgga ttgactgcat
    20221 tatacagaca tctcccaatc ttgcaaatga taattgttcc tattttttaa aaaatttata
    20281 aattattgat ggatatgtga attaatttta agatttaaaa tctctttctc aaaaaaacac
    20341 aaaaatgccg tctgaaacgt gttcagacgg cattggctgc acagccagtc cgtttaaaat
    20401 ttcacgccct tatgcagcgc gacgatgccc gcactcatat tgtgataatc cacgctgtca
    20461 aagcccgcat ccagcatcat ctgtttcaaa gtttcctgat cggggtgcat acggatggat
    20521 tcggcgagat attgataact ctccgcatct ttggcaatca gtttgcccat gaccggcagc
    20581 agcttgaacg aatagaaatc atacgcgcct tccaaaggtt tgtagatttt ggaaaactcc
    20641 aataccagca atgtcccgcc gggtttcaaa acacggtaca tctctttcag cgcggcatct
    20701 ttatgcgtca tattccgcaa accgaacgcc acggaaacca agttgaaata attgtcaggg
    20761 aaaggcagtt tttccgcatc ggcaagcgac acgggcaaaa tcatgccttc gttcaaaaga
    20821 cggtcgcgcc cgacggtcag catagaggaa ttaatatcgg tcagccaaac ctcgccttcc
    20881 ttgccgaccc gtttcgccca accgcgcgac aaatcgcccg taccgccggc aatgtccaac
    20941 actttatcgc cttttttcag gtgcgccgtg ttgatggtga aatgcttcca caccctgtgc
    21001 agccctgccg acatcacatc gttcataatg tcgtagtttt tggcgacgga gtggaacact
    21061 tccgccactt ttccggcttt ctcatcttcg ttgaccgtac tgaatccgaa atgcgttttc
    21121 tgtccgccca tattctaacc acctccctga tgccgcccta cggcatccca aacttaacaa
    21181 tctgattgct tttcaaaacg ggaagcaccc gccgccgcca atttgtccaa atattcctgc
    21241 cacatcgcat cgtatccgta tgccagtctg tgcagatacg cccaatcgta aagaccgctg
    21301 tcgtgcccgt ctgaaaaact gattttcagc gcgtactgtc cgacaggctg caaatccgcg
    21361 atttggacat ccgccttgcc ggtctgcaaa acatcctgtc ccacgccgtg tccgcgcact
    21421 tccgcactcg gcgaatagac gcgtaaaaat tcggcaggca gatttttagg ttcgtcccca
    21481 taagtcaaaa ccaacacggt acggtttttc aacaaacgga tttcaacagg aatattattc
    21541 aaaaaacacc tcggttcggc atacaatatc cggcaggcgt acgcgtgcct ttaaacggcg
    21601 cgtattttaa cagctttatc ccgataccga tattcaaacc cacactttaa acggcattga
    21661 tatggacaat ctcgtatggg acggcgttcc cgacatccgc acactcgacc aaaccatccg
    21721 caaacacgca cacccgctca acctgattgt ctgcctcccc gataatcaga ttcccgattt
    21781 tcaaaccgca caagatgctt cggacgcgga atgccgtctg aagcaccgtt tggatcaggc
    21841 aacgcagtgc ctccagttcg acagcatcaa cctcatcgaa cacatcctgc ccgatgtccg
    21901 cttctggctg gttccccctt cacgcacccg ccgcctgcac gaacacttcc accacatttc
    21961 ctggcagacc gaagccatcc cgcaaaccga aagcaaaccc gacaaaccct ggtttgcact
    22021 tccacaaaca tccgaacggc aaaaaccgga atacatcctc gttatcggcg cgggcatatc
    22081 cggcgcggca accgcccacg ccttagcatc acacggcatt tccgttaccg tattggaagc
    22141 ccgaaaagcc gcccaagccg ccagcggcaa ccgccaaggg ctgctctacg ccaaaatctc
    22201 gccgcacgac accgaacaaa ccgaactgct gcttgccggc tacggctaca ccaaacgcct
    22261 gctcggacac atcctgcccg aatccgacac ttggggcggc aacggcatca tccacctcaa
    22321 ttacagccgc atcgaacaac aacgcaatca cgaattgggt ttgcaaaaac accataacca
    22381 cctctaccgc agcatcacgt ctgcagaagc cgaaaaaatc gccggtatcc cactgtccgt
    22441 cccatacgac cacccttcat gcggactcta ctggcaacac ggcgtatggc tcaatccacc
    22501 cgcattcgtc cgcgccctcc tcaaccatcc gctcattgga ctacacgaag acacaccgtt
    22561 aaccgacatt tcccacgacg gggaaaagtg gattgcaagc acgccaaacg gcatattttc
    22621 cgccacacac atcatctact gcaccggcgc gcacagctcc tgcctgcccg aaaccaacct
    22681 cgccgccctg cctctcaggc aaatacgcgg acaaaccggc ctcacaccat ccaccccgtt
    22741 ttccgaacaa ctgcgttgcg ccgtttcagg cgaaagctac atcagcccgt cgtggcacgg
    22801 actgcactgc tacggcgcga gttttattcc caacagcagc cataccggat ggaacgaagc
    22861 cgaagaagcc tcaaaccgcc aagcattggc acagcttagc cccgccctcg ccgaatcatt
    22921 gtttgccgcc aacccaatcc cccaaaaaca ccaagggcac gccgccatgc gctgcgacag
    22981 ccccgaccac cttcccctag tcggcgcact cggcgacatt gccgctatgc aacaaactta
    23041 cgccaaactc gcgctggaca aaaactatcg catcgacgcc ccctgcccgt acctgcccaa
    23101 tgcctacgcc aacaccgccc acggcacacg cgggcttgcc accgccccca tctgcgccgc
    23161 cgccgttgca gccgaaatcc taggcttgcc ccatcccctc tcaaaacgcc tgcgccacgc
    23221 cctacacccc aaccgcacca tcatccgcgc catcgtcaga aggaaggatc taacccttaa
    23281 gcctttgccg catgccgtcc cgaccacaga aaatcatatt caaataaaca taccaatcct
    23341 gacggtaaaa tatcgaaaac acccataacg ttttcttccc aaaataagga gtaaggaatg
    23401 cctaacaaat tgcctttgct gtccaagatg aatattccgt aacattcgaa gacttcctta
    23461 accctgccag ccgtttcggt ttctgtaccc cctgttagat aaggaaggaa tgaaaaagcc
    23521 ctgttgattg tatgaagtaa agggcgttaa tttttgttaa tcttcccttc tcaggaactc
    23581 aatatataag gatgttaatt tttatttccc ttctcgagga c
//
LOCUS       DAXIDM010000022        23366 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000022 DAXIDM010000000
VERSION     DAXIDM010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 23366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23366
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.022"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            63..1739
                     /gene="pilB"
                     /locus_tag="ACFOAE_000715"
     CDS             63..1739
                     /gene="pilB"
                     /locus_tag="ACFOAE_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV-A pilus assembly ATPase PilB"
                     /protein_id="HFC6884242.1"
                     /translation="MSVGLLRILVQNQVVTVEQAEHYYNESQAGKEVLPMLFSDGVIS
                     PKSLAALIARVFSYSILDLRHYPRHRVLMGVLTEEQMVEFHCVPVFRRGDKVFFAVSD
                     PTQMPQIQKTVSAAGIEVELVIVEDDQLAGLLDWVGSRSTSLLQELGEGQEEEESHTL
                     YIDNEEAEDGPVPRFIHKTLSDALRSGASDIHFEFYEHNARIRFRVDGQLREVVQPPI
                     AVRGQLASRIKVMSRLDISEKRIPQDGRMQLTFQKGGKPVDFRVSTLPTLFGEKVVMR
                     ILNSDAASLNIDQLGFEPFQKKLLLEAIHRPYGMVLVTGPTGSGKTVSLYTCLNILNT
                     ESVNIATAEDPAEINLPGINQVNVNDKQGLTFAAALKSFLRQDPDIIMVGEIRDLETA
                     DIAIKAAQTGHMVFSTLHTNNAPATLSRMLNMGVAPFNIASSVSLIMAQRLLRRLCSS
                     CKQEVERPSASALKEVGFTDEDLAKDWKLYRAVGCDRCRGQGYKGRAGVYEVMPISEE
                     MQRVIMNNGTEVDILDVAYKEGMVDLRRAGILKVMQGITSLEEVTANTND"
     gene            complement(1824..2033)
                     /locus_tag="ACFOAE_000716"
     CDS             complement(1824..2033)
                     /locus_tag="ACFOAE_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HFC6884243.1"
                     /translation="MTESRQTRLQVKCPTCQTTVVWKPENAFRPFCSQRCKLIDLGGW
                     ADGKYTVSDQTESLLEISEPDGAYR"
     gene            complement(2026..2658)
                     /gene="coaE"
                     /locus_tag="ACFOAE_000717"
     CDS             complement(2026..2658)
                     /gene="coaE"
                     /locus_tag="ACFOAE_000717"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258461.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFC6884244.1"
                     /translation="MTVWVGLTGGIGSGKSAAAQCFADLGVPRIDADAAAHSLTASDG
                     IALPEIRRLFGDTVFDTQGLLRRDILRKEVFASPSRKALLESVMLPLIFSEIKKQQET
                     FTDAAYGIVEIPLLTEKRQFIILIRRVLTISAPVEKRIGRVMARSGLTRGEVAAVISH
                     QASESERLLLADDVLLNDGSLKSLREKTMRLHAFYSGIFASKPTQGKHND"
     gene            complement(2660..3520)
                     /locus_tag="ACFOAE_000718"
     CDS             complement(2660..3520)
                     /locus_tag="ACFOAE_000718"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFC6884245.1"
                     /translation="MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVF
                     AKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAWQNIPIVSYLLLRGKCASCQTKI
                     SIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
                     LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAAL
                     GAWLGISALPVLIFVSSLIGLVAAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRA
                     VNWWLTHPVL"
     gene            complement(3594..4826)
                     /gene="pilG"
                     /locus_tag="ACFOAE_000719"
     CDS             complement(3594..4826)
                     /gene="pilG"
                     /locus_tag="ACFOAE_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4 pilus assembly protein PilG"
                     /protein_id="HFC6884246.1"
                     /translation="MAKNGGFSLFAKKEKRFIFEGRHSASDKLVNGEVSAFTEEEARK
                     KLAKRGIRPLQITRVKTSSKRKITQEDITVFTRQLSTMIKAGLPLMQAFEIVARGHGN
                     PSMTEMLMEIRGEVEQGSSLSRAFSNHPKYFDRFYCNLVAAGETGGVLESLLDKLAIY
                     KEKTQAIRKKVKTALTYPVSVIAVAIGLVFVMMIFVLPAFKEVYANMGAELPALTQTV
                     MDMSDFFVSYGWMVLIALGFAIYGFLKLKARSIKIQRRMDAILLRMPIFGDIVRKGTI
                     ARWGRTTATLIAAGVPLVDVLDSTAGAAGNLIYEEATREIRTRVIQGLSMTSGMRATE
                     LFPNMMLQMSSIGEESGSLDDMLNKAAEFYEDEVDNAVGRLSAMMEPIIIVILGLVIG
                     TLLVAMYLPLFNLGNVVA"
     gene            5183..6826
                     /gene="pgi"
                     /locus_tag="ACFOAE_000720"
     CDS             5183..6826
                     /gene="pgi"
                     /locus_tag="ACFOAE_000720"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFC6884247.1"
                     /translation="MNAFTRAWYALERHYQDTRHVLLRDRFACEPDRFERMHERLDGM
                     LFDYSKNRLGEDTLQLLCNLADAADLEGKMRALRTGAKVNNSEGRAALHTALRLPDGA
                     GAVYADGRDVLPEIRRELNRALKFAHSLDDGSYQGTTGKRITDFVHIGIGGSDLGPAM
                     CVQALEPFRRHIAVHFAANADPACLDEVLCRLNPETTVFCVASKSFKTPETLLNAEAV
                     KAWYRGAGFSESETARHFCAVSADTAAAAAFGIAAERVFAMYDWVGGRYSVWSPVGLP
                     VMVAVGGARFRELLAGAHAMDSHFFHTPPRRNIPVLMALIAVWYNNFQHADGQTAVPY
                     SHNLRLLPVWLNQLDMESLGKSRASDGSPAVCKTGGIVFGGEGVNCQHAYFQLLHQGT
                     RLIPCDFIVPVTAQGVEDGRSRFTVANAFAQAEALMKGKTLDEARAELADLPEAERER
                     LAPHKEFPGNRPSNSILLDRLTPYNLGMLMAAYEHKTFVQGAIWNVNPFDQWGVEYGK
                     QLAKTIIGELEGGTSVHDASTEGLMAFYRECRLKGGGAA"
     gene            6993..7814
                     /gene="dapD"
                     /locus_tag="ACFOAE_000721"
     CDS             6993..7814
                     /gene="dapD"
                     /locus_tag="ACFOAE_000721"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008666 -
                     2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HFC6884248.1"
                     /translation="MSLQNIIETAFENRADITPSTVAPEVKEAVLETIRQLDSGKLRV
                     AERLGVGEWKVNEWAKKAVLLSFRIQDNEVLNDGVNKYFDKVPTKFADWSEDEFKNAG
                     FRAVPGAVARRGSFVAKNVVLMPSYVNIGAYVDEGAMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQAAPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVFIGQSTKIFDRT
                     TGEIYQGRVPAGSVVVSGSMPSKDGSHSLYCAVIVKRVDAQTRAKTSVNELLRGI"
     gene            7969..8754
                     /gene="fabI"
                     /locus_tag="ACFOAE_000722"
     CDS             7969..8754
                     /gene="fabI"
                     /locus_tag="ACFOAE_000722"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFC6884249.1"
                     /translation="MGFLQGKKILITGMISERSIAYGIAKACREQGADLAFTYVVDKL
                     EERVRKMAAELDSELVFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSG
                     DFLDSISREAFNTAHEISAYSLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVM
                     GMAKASLEAGIRFTAACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLR
                     RNVTIEEVGNTAAFLLSDLSSGITGEITYVDGGYSINALSTEG"
     gene            complement(8998..9996)
                     /gene="ilvE"
                     /locus_tag="ACFOAE_000723"
     CDS             complement(8998..9996)
                     /gene="ilvE"
                     /locus_tag="ACFOAE_000723"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HFC6884250.1"
                     /translation="MSRPVPAVFGSVFHSQMPVLAYREGKWQPTEWQSSQDLSLVPGA
                     HALHYGSECFEGLKAFRQADGKIVLFRPTANIARMRQSADILHLPRPETQAYLDALVE
                     LVKRAADEIPDAPAALYLRPTLIGTDPVIGKAGSPSETALLYILASPVGDYFKVGSPV
                     KILVETEHIRCAPHMGRVKCGGNYASAMHWVLKAKAEYGANQVLFCPNGDVQETGASN
                     FILINGDEIITKPLTDEFLHGVTRDSVLTVAKDLGYTVSERNFTVDELKAAVENGAEA
                     ILTGTAAVISPVTSFVIGGKEIEVKSQERGYAIRKAITDIQYGLAEDKYGWLVEVC"
     gene            10306..10620
                     /locus_tag="ACFOAE_000724"
     CDS             10306..10620
                     /locus_tag="ACFOAE_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly LapA
                     domain-containing protein"
                     /protein_id="HFC6884251.1"
                     /translation="MKLIYTVIKIIILLLFLLLAVINTDAVTFSYLPGQKFDLPLIVV
                     LFGAFVVGIIFGMFALFGRLLSLRGENGRLRAEVKKNARLTGKELTAPPAQNAPESTK
                     QP"
     gene            10631..11800
                     /gene="lapB"
                     /locus_tag="ACFOAE_000725"
     CDS             10631..11800
                     /gene="lapB"
                     /locus_tag="ACFOAE_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0008653 - lipopolysaccharide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HFC6884252.1"
                     /translation="MDNELWIILLPIILLPVFFAMGWFAARVDMKTVLKQAKSIPSGF
                     YKSLDALVDRNSGRAARELAEVIDQQPQSYDLNLTLGKLYRQRGENDKAINIHRTMLD
                     SPDTVGEKRARVLFELAQNYQSAGLVDRAEQIFLGLQDGKMAREARQHLLNIYQQDRD
                     WEKAVETARLLSHDDQTYQFEIAQFYCELAQAALFKSNFDVARFNVGKALEANKKCTR
                     ANMILGDIEHRQGNFPAAVEAYAAIEQQNHAYLSMVGEKLYEAYAAQGKPEEGLNRLT
                     GYMQTFPELDLINVVYEKSLLLKCEKEAAQTAVELVRRKPDLNGVYRLLGLKLSDLDP
                     AWKADADMMRSVIGRQLQRSVMYRCRNCHFKSQVFFWHCPACNKWQTFTPNKIEV"
     gene            11825..12241
                     /gene="gloA"
                     /locus_tag="ACFOAE_000726"
     CDS             11825..12241
                     /gene="gloA"
                     /locus_tag="ACFOAE_000726"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004462 - lactoylglutathione lyase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0051596 - methylglyoxal catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFC6884253.1"
                     /translation="MRLLHTMLRVGNLEKSLDFYQNVLGMKLLRRKDYPEGRFTLAFV
                     GYGDETDSTVLELTHNWDTERYDLGNAYGHIAVEVDDAYEACERVKRQGGNVVREAGP
                     MKHGTTVIAFVEDPDGYKIEFIQKKSGDDSVAYQTA"
     gene            complement(12414..14939)
                     /gene="tspA"
                     /locus_tag="ACFOAE_000727"
     CDS             complement(12414..14939)
                     /gene="tspA"
                     /locus_tag="ACFOAE_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_164729270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FimV/HubP family polar landmark-like protein
                     TspA"
                     /protein_id="HFC6884254.1"
                     /translation="MKNNRQIKLIAASVAVAASFQAHAGLGGLNIQSNLDEPFSGSIT
                     VTGEEAKALLGGGSVTVSEKGLTAKVHKLGDKAVIAVSSAQAVRDPVLVFRIGAGAQV
                     REYTAILDPVGYSPKTKSALSDGKTHRKTAPTAESQENQNAKALRKTDKKDSANAAVK
                     PAYNGKTHTVRKGETVKQIAAAIRPKHLTLEQVADALLKANPNVSAHGRLRAGSVLHI
                     PNLNRIKAEQPKPQTAKPKAETASMPSEPSKQATVEKPVEKPEAKVAAPEAKAEKPAV
                     RPEPVPAANTAASETAAESAPQEAAASAIDTPTDETGNAVSEPVEQVSAEEETESGLF
                     DGLFGGSYTLLLAGGGAALIALLLLLRLAQSKRARRTEESVPEEEPDLDDAADDGIEI
                     TFAEVETPATPEPAPKNDVNDTLALDGESEEELSAKQTFDVETDTPSNRIDLDFDSLA
                     AAQNGILSGALTQDEETQKRADADWNAIESTDSVYEPETFNPYNPVEIVIDTPEPESV
                     AQTAENKPETVDTDFSDNLPSNNHIGTEETASAKPASPSGLAGFLKASSPETILEKTV
                     AEVQTPEELHDFLKVYETDAVAETAPETPDFNAAADDLSALLQPAEAPSVEENITETV
                     AETPDFNATADDLSALLQPSKVPAVEENAAETVADDLSALLQPAEAPAVEENVTETVA
                     ETPDFNATADDLSALLQPSEVPAVEENAAETVADDLSALLQPAEAPAVEENAAEITLE
                     TPDSNTSEADALPDFLKDGEEETVDWSIYLSEENIPNNADTSFPSESVGSDAPSEAKY
                     DLAEMYLEIGDRDAAAETVQKLLEEAEGDVLKRAQALAQELGI"
     gene            15247..15777
                     /locus_tag="ACFOAE_000728"
     CDS             15247..15777
                     /locus_tag="ACFOAE_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HFC6884255.1"
                     /translation="MKFVSDLLSVILFFATYTVTKNMIAATAVALVAGVVQAAFLYWK
                     YKKLDTMQWVGLVLIVIFGGATIVLGDSRFIMWKPSVLFWLGALFLWGSHLAGKNGLK
                     ASIGREIQLPDAVWAKLTYMWVGFLIFMGIANWFVFTRFESQWVNYKMFGSTALMLVF
                     FIIQGIYLSTCLKKED"
     gene            15780..16070
                     /locus_tag="ACFOAE_000729"
     CDS             15780..16070
                     /locus_tag="ACFOAE_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HFC6884256.1"
                     /translation="MEYFMLLATDGENVYEARMAARPEHLKRLETLKSEGRLLTAGPN
                     PLPEDSNRVSGSLIVAQFESLDAAEAWAEDDPYVHAGVYSEVLIKPFKAVFK"
     gene            16070..16348
                     /locus_tag="ACFOAE_000730"
     CDS             16070..16348
                     /locus_tag="ACFOAE_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family protein"
                     /protein_id="HFC6884257.1"
                     /translation="MPAVDLIRERLQTLDPLVLEIGDESHLHKGHAGNTGGGHYAVLV
                     VSRHFEGVSRLNRQKTVKSLLKDLFSDGIIHALGIRAAAPDEYFHTAD"
     gene            16397..17263
                     /locus_tag="ACFOAE_000731"
     CDS             16397..17263
                     /locus_tag="ACFOAE_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC6884258.1"
                     /translation="MKAKILTSVALLACSGSLFAQTLATVNGQKIDSSVIDAQVAAFR
                     AENSRAEDTPQLRQSLLENEVVNTVVAQEVKRLKLDRSAEFKNALAKLRAEAKKSGDD
                     KKPSFKTVWQAVKYGLNGEAYALHIAKTQPVSEQEVKAAYDNISGFYKGTQEVQLGEI
                     LTDKEENAKKAVADLKAKKGFDAVLKQYSLNDRTKQTGAPVGYVPLKDLEQGVPPLYQ
                     AIKDLKKGEFTATPLKNGDFYGVYYVNDSREVKVPSFDEMKGQIAGNLQAERIDRAVG
                     ALLGKANIKPAK"
     gene            17334..18092
                     /locus_tag="ACFOAE_000732"
     CDS             17334..18092
                     /locus_tag="ACFOAE_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC6884259.1"
                     /translation="MKQKKTAAAVIAAMLAGFAAAKAPEIDPALVDTLVAQIMQQADR
                     HAEQSQKPDGQAIRNDAVRRLQTLEVLKNRALKEGLDKDKDVQNRFKIAEASFYAEEY
                     VRFLERSETVSESALRQFYERQIRMIKLQQVSFATEEEARQAQQLLLKGLSFEGLMKR
                     YPNDEQAFDGFIMAQQLPEPLASQFAAMNRGDVTRDPVKLGERYYLFKLSEVGKNPDA
                     QPFELVRNQLEQGLRQEKARLKIDAILEENGVKP"
     gene            18166..18657
                     /gene="dtd"
                     /locus_tag="ACFOAE_000733"
     CDS             18166..18657
                     /gene="dtd"
                     /locus_tag="ACFOAE_000733"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFC6884260.1"
                     /translation="MRAVIQKTVGAKVDVVSENGTETCGKIDGGFVVLLGVTHDDTEK
                     DARYIADKIAHLRVFEDEAGKLNLSLKDVGGAVLLVSQFTLYADAASGRRPSFSQAAP
                     AEQAQQLYLRTAELLRGHGIHVETGRFRTHMQVSLCNDGPVTILLDSFMTRISPKMKV
                     VPD"
     gene            18688..19698
                     /gene="dusA"
                     /locus_tag="ACFOAE_000734"
     CDS             18688..19698
                     /gene="dusA"
                     /locus_tag="ACFOAE_000734"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0002943 - tRNA dihydrouridine synthesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HFC6884261.1"
                     /translation="MNDNTHTLPPRRLSVAPMLDWTDRHYRYMARQITRNAWLYSEMV
                     NAGAIVYGDKDRFLMFNEGEQPVALQLGGSDPSDLAKAAKAAEAYGYNEVNLNCGCPS
                     PRVQKGSFGACLMNEVGLVADCLNAMQDAVGIPVTVKHRIGVDRQTEYQTVADFVGTL
                     RDKTACKTFIVHARNAWLDGLSPKENRDVPPLKYDYVYRLKQEFPGLEIIINGGITTN
                     EAIAGHLQHVDGVMVGREAYHNPMVMREWDRLFYGDTANPIGYADLVQRLYTYSQAQI
                     QAGRGTILRHIVRHSLGLMHGLKGARTWRRMLSDATLLKDNDGSLILEAWKEVERANT
                     RE"
     gene            complement(19768..20655)
                     /gene="gluQRS"
                     /locus_tag="ACFOAE_000735"
     CDS             complement(19768..20655)
                     /gene="gluQRS"
                     /locus_tag="ACFOAE_000735"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HFC6884262.1"
                     /translation="MYTGRFAPSPTGLLHIGSLLTAVASYADARAHGGRWLVRMEDLD
                     PPREMPGAASHILHTLEAFGFEWYGEVAYQSRRYALYEETLCRLKTAGLVYPCHCSRK
                     DWQAAAVHGADGFVYNGRCRNPQQRPALQGKQPAWRIRVPDRDIGFSDGIVGGYAQNL
                     ARDIGDFVLLRADGYWAYQLAVVADDAEQGVTHIVRGQDLLVSTPRQIYLQQCLGVPT
                     PQYAHLPLLTNAQGQKWSKQTLAPALDLNRREQLLRQVFRYLNLPEAPEADRPAELLD
                     WAVAHWDMDKVPKHAITTP"
     gene            complement(20672..20962)
                     /locus_tag="ACFOAE_000736"
     CDS             complement(20672..20962)
                     /locus_tag="ACFOAE_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884263.1"
                     /translation="MAKALEIISPNEIYSDLIFKDPVPPHTIYTELMKLVSRNASNER
                     IADRAFDFFSSGLMDGSATEEQYNALYDLTLLEEPGMELNKDEIMALINSLK"
     gene            complement(20967..21101)
                     /locus_tag="ACFOAE_000737"
     CDS             complement(20967..21101)
                     /locus_tag="ACFOAE_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884264.1"
                     /translation="MPSERLSDGIALLTGHSAAYQGFALKILMGKKLMHDITRQHKRK
                     "
     gene            complement(21116..22171)
                     /gene="tal"
                     /locus_tag="ACFOAE_000738"
     CDS             complement(21116..22171)
                     /gene="tal"
                     /locus_tag="ACFOAE_000738"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004801 - transaldolase activity [Evidence
                     IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HFC6884265.1"
                     /translation="MTILSDVKALGQQIWLDNLSRSLVQSGELAQMLKQGVCGVTSNP
                     AIFQKAFAGDALYADEVAALKQQDLTPKQRYETMAVADVRAACGVCLAEHESTGGKTG
                     FVSLEVSPELSKDAQGTVEEARRLYAAIGCKNAMIKVPATDAGIDALETLVSDGISVN
                     LTLLFSRAQTLKAYAAYARGIAKRLAAGQSVAHIHVVASFFISRVDSALDTTLPDRLK
                     GKIAIALAKAAYQDWEQYFTAPEFAALEAQGANRVQLLWASTGVKNPAYPDTLYVDSL
                     IGAHTVNTVPDATLKAFIDHGTAKATLTEGVEEAQAQLAETAALGIDVETLATRLQED
                     GLKQFEEAFEKLLAPLV"
     gene            22268..23242
                     /locus_tag="ACFOAE_000739"
     CDS             22268..23242
                     /locus_tag="ACFOAE_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="KpsF/GutQ family sugar-phosphate isomerase"
                     /protein_id="HFC6884266.1"
                     /translation="MAENGKYLDWAREVLHTEAEGLREIAADLDENFALAADALLHCK
                     GRVVITGMGKSGHIGRKMAATMASTGTPAFFVHPAEAAHGDLGMIVDNDVVVAISNSG
                     ESDEIAAIIPALKRKDITLVCITARPDSTMARHADIHITASVSKEACPLGLAPTTSTT
                     AVMALGDALAVVLLRARAFTPDDFALSHPAGSLGKRLLLRVADIMHKGGGLPAVRLST
                     PLKEAIVSMSEKGLGMLAVTDGQGRLKGVFTDGDLRRLFQECDNFTGLSIDEVMHTHP
                     KTISAERLATEALKVMQANHVNGLLVTDADGVLIGALNMHDLLAARIV"
BASE COUNT         5229 a         6003 c         6681 g         5453 t
ORIGIN      
        1 aatttaatcc actataaaag ctgtacaggt ataacaatga ataaatttgg ggataaggtc
       61 gtatgagcgt aggtttgctg aggattctgg ttcaaaacca ggtggttact gttgagcagg
      121 ccgagcatta ctacaatgag tcgcaggcgg gtaaggaagt gttgccgatg ctgttttcag
      181 acggtgtcat ttcgcccaag tcgcttgcgg cattgattgc gagggtgttc agttattcga
      241 ttcttgattt gcgtcattat ccgcgccaca gggtgctgat gggggtgttg acggaggagc
      301 agatggtgga gttccactgt gtgccggttt tccgtcgggg cgacaaagta ttttttgcgg
      361 tttccgatcc gacacagatg ccgcaaattc agaaaaccgt ttctgccgca gggattgagg
      421 ttgagttggt cattgtcgag gatgaccagt tggcgggttt gctcgattgg gtgggttcgc
      481 gttcgacatc gctgcttcag gagcttgggg aggggcagga ggaagaggaa agccacaccc
      541 tgtatatcga caacgaggag gcagaagacg gccctgttcc gaggtttatc cataagactt
      601 tgtcggatgc cttgcgcagc ggggcatcgg acatccattt cgagttttac gaacacaatg
      661 cccgtatccg tttccgtgtg gacgggcagc tccgcgaggt ggttcagccg cccattgcgg
      721 taagggggca gcttgcttcc cggattaagg taatgtcgcg tttggacatt tccgaaaaac
      781 ggataccgca ggacggcagg atgcagctga cctttcaaaa gggcggcaag cctgtcgatt
      841 tccgtgtcag cacattgccg acgctgtttg gcgaaaaggt cgtgatgcgg attttgaatt
      901 ccgatgccgc gtctttgaac atcgaccagc tcggttttga gccgtttcag aaaaaattgt
      961 tgttggaagc gattcaccgt ccctacggga tggtgttggt aaccggtccg acaggttcgg
     1021 gaaagactgt gtcgctctat acctgtttga atattttgaa tacggagtcg gtaaatattg
     1081 caacggcgga agaccctgcc gagattaacc tgccgggcat caatcaggtt aacgtcaatg
     1141 ataagcaggg tctgactttt gccgctgctt tgaagtcttt cctgcgtcag gacccggaca
     1201 tcattatggt cggtgagatt cgtgatttgg aaactgccga tattgcgatt aaggcggcac
     1261 aaacagggca tatggtgttt tccaccctgc acaccaataa tgcgccggcg acgttgtcgc
     1321 gtatgctgaa tatgggtgtc gcgccgttta atattgccag ttcggtcagc ctgattatgg
     1381 cgcagcgtct tttacgcagg ctgtgttcga gctgcaaaca ggaagtggaa cgcccgtctg
     1441 cctctgcttt gaaggaagtc ggcttcaccg atgaggacct tgcaaaagat tggaaacttt
     1501 accgcgccgt cggttgcgac cgttgccggg ggcagggtta taaagggcgt gcgggcgtgt
     1561 atgaggttat gcccatcagc gaagaaatgc agcgcgtgat tatgaacaac ggtacggaag
     1621 tggatatttt ggacgttgcc tataaggagg gtatggtgga tttgcgccgg gccggtattt
     1681 tgaaagttat gcagggcatt acctcgttgg aagaggtaac ggcaaatacc aacgattagg
     1741 cttgggaatg aaaatgccgt ctgaagcgtg tttgtttcag acggcatttg attttcaggg
     1801 gtttgccgga gggcggggtg cggtcagcgg tatgcgccgt ccggttcgga tatttccagc
     1861 aaactttccg tttggtcgga aaccgtatat ttcccgtctg cccatccgcc caagtcgatc
     1921 agtttgcagc gttgcgaaca gaacgggcgg aatgcgtttt cgggtttcca tactactgtc
     1981 gtttgacagg tcggacattt gacttgaagg cgtgtttgcc gcgattcagt cattgtgttt
     2041 tccttgtgtt ggttttgagg cgaaaatccc tgaataaaac gcgtgcaggc gcattgtttt
     2101 ctcacgcagg cttttgaggc tgccgtcatt gagcagcaca tcgtctgcaa gcagcaggcg
     2161 ttcggattcg gatgcctgat ggctgatgac ggcagccacc tcgccgcgcg tcagcccgct
     2221 gcgggccatc accctgccga tacgtttttc cacaggggca cttatggtca ggacacgccg
     2281 tatcaggatg ataaattgac gcttttccgt cagcagcgga atttcgacaa tgccgtaagc
     2341 cgcatcggta aaggtttctt gctgtttttt gatttctgag aaaatcagcg gcaacatcac
     2401 ggattcgagc aaggcttttc gcgatgggga ggcaaagact tctttacgca atatgtcgcg
     2461 tcgcaacaaa ccctgtgtgt cgaaaacggt gtcgccgaac agccgcctga tttccggcag
     2521 ggcgatgccg tctgaagccg tcagcgagtg cgccgccgca tccgcatcga tacgcggtac
     2581 gcccaaatcg gcaaaacatt gcgcggctgc cgatttgccg ctgccgattc cgccggtcag
     2641 tccgacccat accgtcatct tacagcaccg gatgggtcag ccaccagttg accgcccgcc
     2701 atacggaatc gtttgccgta aaaattatcc agcccgaaac tgtcagtgcg gggccgaagg
     2761 caaaatgctg ccccttggcg acgcgcataa cgattgccgc gaccaaaccg atcagcgagg
     2821 aaacaaaaat cagcacgggc aatgcggata tgccgagcca cgcgcccaat gcggcaatca
     2881 gtttgaaatc tccgttgccc ataccgattt cgcctttaat cagtttatat accgcgcata
     2941 aaagccatat cgaaccatag ccggcaaccg cacctaaaac ggcagactgc aaaggcacga
     3001 agccgccgtc caaattaaat atcagcccca gccaaatcaa gggtaatgtc atcgagtcgg
     3061 gcaggtattg ggtgtccgca tcgataaagg tcagggaaat cagaaacgcg gtcagtatca
     3121 aaccgcccaa tgtaatccaa gaccagccgt attgccaggc aaccagcccg aacaatacgc
     3181 cggtcagcag ttcgattaag ggatagcgta tgctgatttt ggtttggcag gaggcgcatt
     3241 tgccgcgcag gagcaggtag ctgacaatcg ggatgttctg ccacgcgcgt atcggcacgc
     3301 ggcatttggg acagcaggaa tccggtttca tcaggttgaa ggtacggctt tcctcttcgg
     3361 tcagcggcag gtttaaatat tctttggcaa ataccgtcca gccgcgttcc atcatgaccg
     3421 gcacgcggta aatgacgaca tttaagaaac ttccgaccag cagcccgaac accgctgtca
     3481 aaggcacggc aaacggcgac aatacagaca aatcagacat attttgttct caatgtattc
     3541 aaaacaaaaa caaaccggcg cagagcgaat ccgcgccgga tctgtgcggc aaatcaggcg
     3601 accacgttgc ccaaattaaa cagcggcaga tacatggcga ccagaagcgt gccgatgacc
     3661 aagcctaaaa tcacgataat gatcggctcc atcatagcgg acagcctgcc gaccgcattg
     3721 tccacctcgt cttcgtaaaa ttcggcggct ttgttgagca tatcgtccaa agaacccgat
     3781 tcctcgccga tggaagacat ctgcaacatc atattgggga acagttccgt cgcacgcatc
     3841 cccgaagtca tagacaaacc ttggatgacg cgcgtacgga tttcccgggt ggcttcttca
     3901 tagattaaat tgcccgccgc gccggcagtg gagtccaata catcgaccaa aggcacgcct
     3961 gccgcaatca gcgtcgccgt cgtcctgccc cagcgggcaa tcgtcccttt gcggacaatg
     4021 tctccgaaaa tcggcatacg cagcagtatg gcatccatac gccgttggat tttaatcgaa
     4081 cgcgccttca atttaaggaa gccgtatatg gcaaagccca gtgcgatcag caccatccag
     4141 ccgtatgaga cgaaaaagtc ggacatatcc atcactgttt gggtcagtgc gggaagctcc
     4201 gcgcccatat tggcgtaaac ttctttaaag gcgggcagta cgaaaatcat catcacgaat
     4261 accaaaccga tggcgacggc gatgacggat accggatagg tcagtgcggt ttttaccttt
     4321 ttgcggatgg cctgggtttt ttctttgtaa attgccaatt tgtccagcag gctttccaat
     4381 acgccgcccg tttcgcccgc cgcaaccaga ttgcagtaga agcggtcgaa atattttggg
     4441 tggtttgaga atgcgcggct caacgagctg ccctgttcca cttcgcctcg gatttccatc
     4501 agcatttccg tcatagacgg gttgccgtgt ccgcgcgcca cgatttcaaa tgcctgcatc
     4561 agcggcaggc ccgctttaat catcgtggac agctggcggg tgaaaacggt gatgtcttct
     4621 tgtgtgattt tgcgcttgga gcttgttttc acacgggtaa tctgcaacgg gcggatgccg
     4681 cgttttgcca gttttttgcg cgcctcttct tcggtaaacg cggatacttc gccgttgacc
     4741 agtttgtcgg aggcggaatg cctgccttca aagataaagc gtttttcttt ctttgcgaac
     4801 aaagaaaatc ctccgttttt agccatattc tagccccgta aagtaattgg aataaaatgt
     4861 aagaaacatc gttaaaaaac agtaccggcg tgttcccggt aagatgaaaa ccgccgacat
     4921 cccgcctgcg ggcggcaaac gggacagaat cggatgcgat tataccttat ttaggcggct
     4981 gtccggcatt tatgcgtaca caataaatct tgcaggatat tgttgcgggt caaatgccgg
     5041 ccggagggta tttccgccat atggaaataa ggtgctattg gacgcggcgg gcggtgttcc
     5101 ggagattcgc caaagccgct gccgtttgtt aaactacatt ctgctacatt ttaatccggt
     5161 tctgaaaaat caaggaaaac agatgaatgc ttttacccgt gcatggtatg cgctcgaacg
     5221 ccattatcag gatacgcgtc atgtcctttt gcgcgaccgc tttgcctgcg aacccgaccg
     5281 ttttgagcgt atgcacgagc gtttggacgg gatgttgttc gattacagca aaaaccgttt
     5341 gggcgaagat acgctgcaac tgctctgcaa tcttgccgat gcggcggatt tggaagggaa
     5401 aatgcgtgct ttgcggacgg gtgcgaaggt caacaacagt gaggggcgtg ccgcgctgca
     5461 tacggctttg cgcctgcccg acggtgcggg tgccgtttat gcggacggca gggacgtgtt
     5521 gcccgaaatc cgccgcgagt taaatcgtgc gttgaagttt gcacacagtt tggacgacgg
     5581 ttcgtatcag gggacaaccg gaaaacggat tacggatttt gtccacatcg gcataggcgg
     5641 atccgacctc gggccggcaa tgtgcgtgca ggcacttgag ccgttcagac ggcatatcgc
     5701 cgtccatttt gccgccaacg ccgatcctgc ctgcctggat gaggtcttat gccgtctgaa
     5761 ccccgaaacg acggtgtttt gcgttgccag caagtccttc aaaacgcctg aaaccctgct
     5821 caatgcagag gcggtcaagg cttggtatcg tggtgcgggg ttctcggaat ccgaaacagc
     5881 acgccatttt tgcgcggtgt ctgccgacac tgcggcagct gcggcttttg gtatcgcggc
     5941 ggaacgcgtg tttgcgatgt acgactgggt gggcggacgc tattccgtct ggtcgcccgt
     6001 cggtttgccc gtgatggttg cggtcggcgg ggcgcgtttc cgcgagttgt tggcgggggc
     6061 gcacgcgatg gacagccatt ttttccacac gccgccgcgc cgcaacattc ccgttctgat
     6121 ggcactgatt gccgtgtggt ataacaattt ccaacacgcg gacgggcaga ccgccgttcc
     6181 gtacagccac aacctgcgcc tgctgccggt gtggctgaac cagctcgata tggagagttt
     6241 gggcaaaagc cgcgcttcag acggcagtcc cgccgtgtgc aaaacgggcg gcatcgtgtt
     6301 cggcggtgaa ggggtcaact gccagcacgc ctatttccaa ctgctccacc aaggcacgcg
     6361 cctaattccc tgcgacttta tcgtcccggt gacggcgcag ggcgtggagg acggacgcag
     6421 ccgttttacc gttgccaacg cctttgccca agcggaagcc ctgatgaagg gcaaaacctt
     6481 ggacgaagca cgcgccgaac tggcagattt gcccgaagcg gaacgcgaac gccttgcgcc
     6541 gcacaaagag ttccctggca accgccccag caacagcatc ctgctcgacc gcctcacgcc
     6601 ctacaatttg ggtatgctga tggcggctta cgaacacaaa accttcgtcc aaggcgcgat
     6661 atggaacgtc aaccccttcg atcagtgggg ggtggaatac ggcaaacagt tggcaaaaac
     6721 catcatcggc gaactggaag gcggcacgtc cgtacacgat gcctcgaccg aagggctgat
     6781 ggcgttttac cgcgaatgcc gtctgaaagg cggcggtgcg gcataaaggt actgccgccc
     6841 gcccgattcc gaaacgccaa tgttcggcaa ccgcccgcgt attgctgacg aatatgcgtt
     6901 tgcgtggcac aatagcgcat tcatttcaaa tgaacatact gcccgaaaat accggcaaac
     6961 gtcccacgaa acatctcaca taaggaaaca ttatgtcttt gcaaaacatt atcgaaaccg
     7021 cctttgaaaa ccgcgcggac attaccccgt ccactgttgc tcccgaagtt aaagaagccg
     7081 tgttggaaac catccgccaa ctcgattcag gcaaactgcg cgttgccgaa cgcttgggcg
     7141 tgggcgagtg gaaagtcaac gaatgggcga aaaaagccgt gttgctgtcc ttccgcatcc
     7201 aagacaacga agtcctcaac gacggcgtga acaaatactt cgacaaagtg ccgaccaagt
     7261 ttgccgactg gtctgaagac gagttcaaaa acgcaggctt ccgcgccgtt ccgggtgcgg
     7321 ttgcccgacg cggcagcttt gtggcgaaaa atgtcgtgct gatgccgtct tatgtcaaca
     7381 tcggcgcata cgtcgacgaa ggcgcgatgg tcgatacttg ggcgactgtc ggctcttgcg
     7441 cgcaaatcgg caaaaacgtg cacttgagtg gcggcgtcgg tatcggcggc gtactcgaac
     7501 ccctgcaggc cgcccccacc atcattgaag acaactgctt catcggtgcg cgttctgaaa
     7561 tcgttgaggg tgtgattgtc gaagaaggca gcgtgatttc gatgggcgtg ttcatcggtc
     7621 aatccaccaa aatcttcgac cgcaccacag gcgaaatcta ccaaggccgc gtaccggcag
     7681 gttcggttgt cgtatccggc agtatgcctt ccaaagacgg cagccacagc ctttactgcg
     7741 ccgtcatcgt caaacgtgtg gacgcgcaaa cacgcgccaa aaccagtgtg aacgaattgt
     7801 tgcgcggcat ctgatgcctt aaaccgtatt tgaaacgtcc gatgccgtct gaaatccgct
     7861 tcggacggca ttgccgtttg cacgctgcaa cgtgaaaaca cagaaacagg gacaatttgc
     7921 tataatcaac ggtttagaac gaaccgaaca ctatttgaag gatacaaaat gggctttctg
     7981 caaggcaaaa aaattctgat taccggcatg atttccgagc gttccatcgc ttacggcatc
     8041 gccaaagcct gccgcgaaca aggcgcggat ttggcgttta cctacgttgt ggacaaactg
     8101 gaagagcgcg tccgcaaaat ggcggcggaa ttggattccg aactcgtatt ccgctgcgat
     8161 gtcgccagcg acgacgaaat caaccaagtg ttcgccgatt tgggcaaaca ttgggacggc
     8221 ttggacggtt tggtgcattc catcggtttt gcgccgaaag aagccttgag cggcgacttc
     8281 ctcgatagca tcagccgcga agcgttcaac accgcacacg aaatttccgc atacagcctg
     8341 cccgcattgg caaaagccgc ccgtccgatg atgcgcggca gaaactccgc catcgttgcc
     8401 ctgagctact tgggcgcggt gcgcgcgatt ccgaattaca acgtgatggg tatggcaaaa
     8461 gccagccttg aggcgggcat ccgttttacc gccgcctgtc tgggcaaaga aggcatccgc
     8521 tgcaacggca tttccgccgg tccgatcaaa acactcgccg cctccggcat cgccgatttc
     8581 ggcaaactct tgggacacgt cgccgcccac aatccgctcc gccgcaacgt taccatcgaa
     8641 gaagtcggca ataccgccgc cttcctgctg tccgacctgt cgtccggcat taccggcgaa
     8701 atcacttacg ttgacggcgg ttacagcatc aatgccttga gcaccgaggg ataatctgcc
     8761 gttttcaaat ccgtgcgccg tccgtgccgc atatcggttt cgggcggcgt tttgccgtct
     8821 gaagcgtatt tctagggaaa tgcccgactt acggcaggcg ggatgggaaa tgcggacgct
     8881 tgttttaacc gattgccttt gtgccgactt gctgcaggtg cagcggaaac ggttcggatg
     8941 cgaaaatgcc gtctgaaacg ccaaacgggt ttcagacggc attttttatt taaagcatca
     9001 gcacacttca accagccagc cgtatttgtc ttccgccaaa ccatactgga tgtcggtaat
     9061 cgccttacgg atggcatagc cgcgttcttg gcttttcact tcgatttctt tgccgccgat
     9121 gacgaaggaa gtaacgggcg agatgacggc tgccgtaccg gtcagaatcg cctccgcacc
     9181 gttttccacc gcagctttga gttcgtcaac cgtgaaattg cgttcgctga cggtatagcc
     9241 caaatctttg gcaaccgtca gtacggaatc gcgggttacg ccgtgcaaaa attcgtcggt
     9301 cagcggtttg gtaatgattt catcgccgtt aatcaggata aagttggacg cgccggtttc
     9361 ctgcacgtcg ccgttcgggc agaagaggac ttggtttgcg ccgtattcgg ctttcgcctt
     9421 cagcacccag tgcatggcgg aagcgtagtt gccgccgcat ttgacgcggc ccatatgcgg
     9481 ggcgcagcgg atatgttcgg tttccaccaa gattttaacg ggcgagccga ctttgaaata
     9541 gtcgccgacg ggggaagcca aaatatacag cagggcggtt tcggaaggag aaccggcctt
     9601 gccgatgacg ggatcggtac cgattaaggt cgggcgcagg tacagggcgg caggcgcatc
     9661 gggaatttcg tcggcggcac gtttgaccag ttcgaccaaa gcatcgagat aggcttgggt
     9721 ttcggggcgg ggcaggtgca aaatgtccgc actttgccgc atacgcgcga tattggcagt
     9781 cggacggaac agtacgattt taccgtctgc ctgacggaag gctttcagtc cctcgaaaca
     9841 ttcgctgccg tagtgcaggg cgtgcgcacc cggtacgagg gagaggtctt gggaagattg
     9901 ccattcggtc ggctgccatt tgccttcgcg gtaggcgagg acgggcattt gactgtgaaa
     9961 aacgctgccg aatacggcgg gtacgggtct gctcatgatg taaagccttt cttattctga
    10021 tatgtttcaa tgaacggttt gaatttgaag attgtaaaga tacgcctgca aacagggttt
    10081 tgacaagtgc gcggcgggtt tttctgtcga tgcggtgtcc aatccgttat ttttcaaatg
    10141 gaaaggaacg gtgtatttgg taaaattgtc ggcaatcgca tactccgtat gtcgtccgaa
    10201 cacgctgccg catcctatcc gaaaccgtgc aaatcgttta aactagcgca atcttggttc
    10261 agagtgcgaa gctgtccggg cggcgttttt atttacggag caaacatgaa acttatctat
    10321 accgtcatca aaatcattat cctgctgctc ttcctgctgc ttgccgtcat taatacggat
    10381 gccgttacct tttcctacct gccggggcaa aaattcgatt tgccgctgat tgtcgtattg
    10441 ttcggcgcat ttgtagtcgg tattattttt ggaatgtttg ccttgttcgg acggttgttg
    10501 tcgttacgtg gcgagaacgg caggttgcgt gccgaagtaa agaaaaatgc gcgtttgacg
    10561 gggaaggagc tgaccgcacc accggcgcaa aatgcgcccg aatctaccaa acagccttaa
    10621 gaaagccgat atggacaacg aattgtggat tatcctgctg ccgattatcc ttttgcccgt
    10681 tttcttcgcg atgggctggt ttgccgcccg tgtggatatg aagactgtat taaagcaggc
    10741 aaaaagcata ccgtcgggat tttataaaag tctggatgcc ttggttgacc gcaacagcgg
    10801 acgtgccgcc agggaattgg cagaggtcat tgatcagcag cctcagtcat acgacctaaa
    10861 cctcacccta ggcaagcttt accgtcagcg tggcgaaaac gacaaagcca tcaacataca
    10921 ccggacaatg ctcgattctc ccgatacggt cggcgaaaag cgcgcgcgcg tcctgtttga
    10981 attggcgcaa aactaccaaa gtgcggggtt ggtcgatcgt gccgaacaga tttttttggg
    11041 gctgcaagac ggtaaaatgg cgcgtgaagc cagacagcac ctgctcaata tctaccaaca
    11101 ggacagggat tgggaaaaag cggttgaaac cgcccggctg ctcagccatg acgatcagac
    11161 ctatcagttt gaaatcgccc agttttattg cgaacttgcc caagccgcgc tgttcaagtc
    11221 caatttcgat gtcgcgcgtt tcaatgtcgg caaggcactc gaagccaaca aaaaatgcac
    11281 ccgtgccaac atgattttgg gcgacatcga acaccgacaa ggcaatttcc ctgccgccgt
    11341 cgaagcctat gccgccatcg agcagcaaaa ccatgcatac ttgagcatgg tcggcgagaa
    11401 gctttacgaa gcctatgccg cgcagggaaa acctgaagaa ggcttgaacc gtctgacagg
    11461 atatatgcag acgtttcccg aacttgacct gatcaatgtc gtgtacgaga aatccctgct
    11521 gcttaagtgc gagaaagaag ccgcgcaaac cgccgtcgag cttgtccgcc gcaagcccga
    11581 cctcaacggc gtgtaccgcc tgcttggttt gaaactcagc gatttggatc cggcttggaa
    11641 agccgatgcc gatatgatgc gttcggttat cggacggcag ctacagcgca gcgtgatgta
    11701 ccggtgccga aactgccact tcaaatcaca agtctttttc tggcactgcc ccgcctgcaa
    11761 caaatggcag acgtttaccc cgaataaaat cgaagtttaa ccaccaccga aaggaacaca
    11821 aaaaatgcgc ttactccata ctatgctccg cgtgggcaat ctcgaaaaat ccctcgattt
    11881 ctaccaaaac gttttgggta tgaaactgct ccgccgaaaa gattatcccg aaggcagatt
    11941 tacccttgcc ttcgtcggtt acggcgatga aaccgacagc acggttttgg aactgacgca
    12001 caactgggat acggaacgat acgacttggg caacgcctac ggacacatcg cggttgaagt
    12061 ggacgatgcc tacgaagcct gcgaacgtgt gaagcggcag ggcggaaacg tcgtccgcga
    12121 agccggcccg atgaaacacg gcacaaccgt gatagccttc gtcgaagacc ccgacggata
    12181 caaaatcgag ttcattcaaa agaaaagcgg cgacgattcg gttgcctatc aaactgcctg
    12241 ataccgccgc cgccaatgcc gtctgaagcc tttagggggt tcagacggca ttttgttgcc
    12301 gtcgacctgc tgtttgagcc tgtgccggtt caaactttat ccgttacacc gataaggcaa
    12361 aaaaagatgc cgtctgaaac ggcatccttg atctgcgaaa gggcagttgg gaatcaaata
    12421 cccaattcct gcgccaatgc ttgggcacgt ttgagtacgt cgccttccgc ttcttccagc
    12481 aatttctgca ctgtctcggc agcggcatcg cggtcgccga tttcgagata catttcggca
    12541 aggtcgtatt tcgcttcgga aggcgcgtca gaacctacag attccgaagg gaaactggta
    12601 tctgcattat ttgggatatt ttcttccgag aggtagatgc tccaatctac cgtttcctcc
    12661 tcgccgtctt tcaggaagtc gggcaaagcg tctgcctcag aggtgttgga atcaggcgtt
    12721 tccaaagtga tttccgctgc attttcctca acggccggtg cttcagcagg ttgcaacagt
    12781 gcggacaaat catcggcaac ggtttccgct gcattttcct caacggcagg tacttcagaa
    12841 ggttgaagta atgcggacaa atcgtctgcg gtggcgttga aatcgggtgt ttcggcaacg
    12901 gtttccgtta cattttcctc aacggccggt gcttcagcag gttgcaacag tgcggacaaa
    12961 tcatcggcaa cggtttccgc tgcattttcc tcaacggcag gtactttaga aggttgaagt
    13021 aatgcggaca aatcgtctgc ggtggcgttg aagtcgggtg tttcggcaac ggtttccgtt
    13081 atattttcct caacggacgg tgcttcggca ggttgaagca atgcggacaa atcgtctgcg
    13141 gcggcgttga aatcgggcgt ttcaggcgca gtttccgcga cggcatcggt ttcgtacact
    13201 ttcaggaaat cgtgcaactc ttccggtgtt tggacttcgg caactgtttt ttccaagatg
    13261 gtttcgggcg aggaagcctt caggaagcct gccagtccgg agggtgaggc aggttttgcg
    13321 gaagctgttt cttctgtgcc gatatggttg tttgagggca ggttgtcgga gaaatcggta
    13381 tcgacggttt ccggtttgtt ttcggcagtt tgggcgacag attccggttc gggcgtgtcg
    13441 atgacgattt cgacagggtt gtacgggttg aaggtctcgg gctcgtacac gctgtctgtg
    13501 gattcgatgg cgttccaatc ggcatccgcg cgtttttggg tttcttcatc ctgcgtaagt
    13561 gcgccggata aaatgccgtt ttgcgcggct gccaggctgt cgaaatccaa gtcgatgcgg
    13621 ttggaaggcg tatcggtttc gacatcgaac gtttgttttg ccgataactc ttcttcagat
    13681 tccccatcta aggcaagtgt gtcgtttaca tcgtttttcg gagcgggttc gggcgttgcc
    13741 ggagtttcga cttcggcaaa ggtgatttct atgccgtcgt ctgccgcgtc gtcaaggtca
    13801 ggctcttcct cagggacgga ttcttcggta cggcgcgcgc gtttggattg ggcaaggcgc
    13861 aaaagcagca gcagggcgat taatgccgcg cctccgccgg caagcagcaa ggtgtacgaa
    13921 ccgccgaaca gaccgtcaaa cagtccgctt tcggtttctt cttcggcaga aacctgttcg
    13981 acaggttcgg aaacggcgtt accggtttcg tcggtcggcg tgtcgatggc agaagcggcg
    14041 gcttcttggg gggcggattc ggcagcggtt tccgatgcgg cagtatttgc agcgggtaca
    14101 ggttcgggtc gaacggccgg tttttccgct tttgcttcgg gcgcggcaac ttttgcttca
    14161 ggtttttcaa ccggtttctc taccgttgcc tgtttggacg gttcggacgg catggatgcg
    14221 gtttcggctt tgggtttcgc cgtttgcggt ttgggttgtt ccgctttgat cctgttcaga
    14281 ttcggaatgt gaagcacgct gcccgcacgc agtctgccgt gtgcggaaac atttgggttt
    14341 gccttcagca gcgcatcggc aacctgttcg agcgtcaggt gtttcgggcg gatggcggcg
    14401 gcaatctgtt tgaccgtttc gcctttgcgg acggtatggg ttttgccgtt gtatgccggt
    14461 ttgacggctg cgttcgcgct gtctttttta tcggttttgc ggagggcttt ggcgttttga
    14521 ttttcttggg actctgctgt cggagcggtt ttgcggtgtg tcttgccgtc tgaaagtgca
    14581 gatttggttt tgggcgagta gccgacagga tcgaggatgg cggtgtattc gcgtacctgt
    14641 gcgcctgcgc cgatgcggaa caccaggacg ggatcgcgga ctgcctgtgc ggaagaaacg
    14701 gcaatgacgg ctttgtcgcc caacttgtgg actttggcgg tcagaccttt ttcggaaacg
    14761 gtaacgctgc cgccgcctag cagggctttg gcttcttcgc cggttacggt aatgctgccg
    14821 gaaaagggtt cgtcaaggtt ggactggata ttcagtccgc ccagtccagc atgtgcctga
    14881 aaggatgcgg caactgcgac ggaggcggca atcagtttga tttgtctgtt gtttttcaag
    14941 atgtatcccc tgtgggttgg cggctgaata cggtttgacc gcgtacagtc tgtaaatttc
    15001 gtcatcatcg ggcatcggcg gggcagtcgg ccggcgggca tttaatatgt gaatgtaccg
    15061 accgccgcca cattttaaac ggcaatcatt cgccgttttt acaaattatg acatatctcc
    15121 atcttttttc aaaaacatct gtgcatattt gcatcaatca aaacaaaatt tgttggtttt
    15181 gcaggtgcaa aaacagggtt ctgcctgtat gattagcgtt tatttgattt gctttctcat
    15241 ttggatatga aattcgtcag cgaccttttg tccgtcatcc tgtttttcgc cacctatacc
    15301 gttaccaaaa atatgattgc cgctacggcg gtcgccttgg ttgccggtgt ggttcaggcg
    15361 gcttttctgt attggaaata taaaaagctg gatacgatgc agtgggtcgg actggtgctg
    15421 attgtgatat tcggtggcgc aaccattgtt ttgggcgaca gccgcttcat tatgtggaag
    15481 ccgagcgttt tgttttggct gggcgcgctg ttcctgtggg gcagccacct cgccggtaaa
    15541 aacggcttga aggcgagtat cggcagggag attcagcttc cggatgccgt atgggcgaaa
    15601 ttgacgtata tgtgggtcgg tttcctgatt tttatgggta tcgccaactg gtttgtgttt
    15661 acccggttcg agtcgcaatg ggtcaactat aaaatgttcg gctcgactgc actgatgctt
    15721 gttttcttta ttattcaggg tatttatctg agtacctgtc tgaaaaagga ggattgactg
    15781 tggaatattt tatgttgctg gcaacagacg gggagaatgt gtatgaagcg cgtatggcgg
    15841 cacgtcccga acacctcaaa cggctggaga cgctgaagtc ggaaggccgg ctgttgacgg
    15901 caggcccgaa tcctttgccg gaggactcca accgcgtttc gggcagtttg attgtggcgc
    15961 agttcgagtc tttggatgcg gcagaggcgt gggcggaaga cgatccctat gttcatgcag
    16021 gcgtgtacag cgaagtgctg atcaagccgt ttaaagcggt gttcaaataa tgccggccgt
    16081 cgatttgatc cgcgaacgcc tgcagacgct cgatccgctg gtgttggaaa tcggcgatga
    16141 gagccatctg cacaaaggac acgcgggcaa taccggcggc ggacattatg ccgtactggt
    16201 cgtcagccgg cattttgaag gcgtaagccg cctgaaccgc cagaaaacgg tcaaatcgct
    16261 gctcaaagat ttgttttcag acggcatcat ccacgcgctc ggcatccggg cggctgcccc
    16321 tgacgagtat ttccatacgg cggactgaat gaagtctgcc cgaacatttc aatttaaaat
    16381 ttaaagagag aagattatga aagcaaaaat cctgacttcc gttgcactgc ttgcctgttc
    16441 cggcagcctg tttgcccaaa cgctggcaac cgtcaacggt cagaaaatcg acagttccgt
    16501 catcgatgcg caggttgccg cattccgtgc ggaaaacagc cgtgccgaag acacgccgca
    16561 actgcgccaa tccctgctgg aaaacgaagt ggtcaacacc gtggtcgcac aggaagtgaa
    16621 acgtctgaaa ctcgaccggt cggcagagtt taaaaatgcg cttgccaaat tgcgtgccga
    16681 agcgaaaaag tcgggcgacg acaagaaacc gtccttcaaa accgtttggc aggcggtaaa
    16741 atatggcttg aacggcgagg catacgcgct gcatatcgcc aaaacccaac cggtttccga
    16801 gcaggaagta aaagccgcat atgacaatat cagcggtttt tacaaaggta cgcaggaagt
    16861 ccagttgggc gaaatcctga ccgacaagga agaaaatgca aaaaaagcgg ttgccgactt
    16921 gaaggcgaaa aaaggtttcg atgccgtctt gaaacaatat tccctcaacg accgtaccaa
    16981 acagaccggc gcgccggtcg gatatgtgcc gctgaaagat ttggaacagg gtgttccgcc
    17041 gctttatcag gcaattaagg acttgaaaaa aggcgaattt acggcaacgc cgctgaaaaa
    17101 cggcgatttc tacggcgttt attatgtcaa cgacagccgc gaggtaaaag tgccttcttt
    17161 tgatgaaatg aaaggacaga ttgccggcaa ccttcaggcg gaacggattg accgtgccgt
    17221 cggtgcactg ttgggcaagg caaacatcaa acctgcaaaa taattctgaa aacgggatat
    17281 ggcggcaaga cgttcagaca ggcgttttgc cgccgcgcag gacagggaat accatgaaac
    17341 agaaaaaaac cgctgccgca gttattgctg caatgttggc aggttttgcg gcagccaaag
    17401 cacccgaaat cgacccggct ttggtggata cgctggtggc gcagatcatg cagcaggcag
    17461 accggcatgc ggagcagtcc caaaaaccgg acgggcaggc aatccgaaac gatgccgtcc
    17521 gtcggctgca aactttggaa gttttgaaaa acagggcatt gaaggaaggt ttggataagg
    17581 ataaggatgt ccaaaaccgc tttaaaatcg ccgaagcgtc tttttatgcc gaggagtacg
    17641 tccgttttct ggaacgttcg gaaacggttt ccgaaagcgc actgcgtcag ttttatgagc
    17701 ggcaaatccg catgatcaaa ttgcagcagg tcagcttcgc aaccgaagag gaggcgcgtc
    17761 aggcgcagca gctcctgctc aaagggctgt cttttgaagg gctgatgaag cgttatccga
    17821 acgacgagca ggcttttgac ggtttcatta tggcgcagca gcttcccgag ccgctggctt
    17881 cgcagtttgc cgcgatgaat cggggcgacg ttacccgcga tccggtcaaa ttgggcgaac
    17941 gctattatct gttcaaactc agcgaggtcg ggaaaaaccc cgacgcgcag cctttcgagt
    18001 tggtcagaaa ccagttggaa caaggtttga gacaggaaaa agcccgcttg aaaatcgatg
    18061 ccattttgga agaaaacggt gtcaaaccgt aatggcattt ccaataccga tgccgtctga
    18121 agccttttca gacggcattg cacgttcagg taaggaggac ggcttatgcg tgcggtcata
    18181 cagaaaacgg taggtgcaaa ggtggatgtc gtgtccgaaa acggcacgga aacctgtggc
    18241 aaaatcgacg gcgggtttgt cgtgttactc ggcgtaacgc acgacgacac agaaaaagat
    18301 gcgcgctata tcgccgacaa aatcgcccat ttgcgcgtgt ttgaagacga agcgggcaag
    18361 ttgaacctgt ctttgaaaga tgtcggcggc gcggtgctgc tggtgtcgca gtttacactt
    18421 tatgccgatg cggcaagcgg gcggcggcct tcgttttccc aagctgcacc tgcagaacag
    18481 gcgcagcagc tttacctgcg aacggcggaa ctgttgcgcg gacacgggat tcatgtcgaa
    18541 acagggcgtt tccgcacgca tatgcaggtg tcgctctgca acgacgggcc ggtaaccata
    18601 ctgctggact ctttcatgac gcggatttcc ccaaaaatga aggttgttcc ggattgaaat
    18661 tgaatctgca atgatgaaat atcgacaatg aacgacaata cacacaccct tcccccgcgc
    18721 cgcctttccg tcgccccgat gctcgactgg acggacaggc actaccgtta tatggcgcgc
    18781 cagattaccc gaaatgcttg gctttacagc gaaatggtca atgccggtgc gattgtttac
    18841 ggcgacaaag accgcttttt gatgttcaac gaaggcgagc agcccgtcgc cctgcaactg
    18901 ggcggcagcg atccgtccga tttggcgaaa gccgccaaag ccgccgaagc atacggctac
    18961 aacgaggtca acctcaactg cggctgcccc agtccgcgcg tgcagaaagg ttcgttcggc
    19021 gcgtgtctga tgaacgaagt cgggctggtt gccgactgcc tcaacgccat gcaggacgcg
    19081 gtcggtattc ccgttaccgt caaacaccgc attggtgtgg acaggcagac cgaataccaa
    19141 accgttgccg atttcgtcgg cacgttgcgc gacaaaaccg cctgcaaaac cttcatcgtc
    19201 cacgcccgca acgcttggct ggacggtctt tcccccaaag aaaaccgcga cgttcccccg
    19261 ttgaaatacg attacgttta ccgcctcaag caggagtttc ccgggctgga aatcatcatc
    19321 aacggcggca tcaccaccaa cgaagcaatc gccggacacc tgcaacacgt tgacggcgtg
    19381 atggtcgggc gcgaggcgta ccacaacccg atggtgatgc gcgaatggga cagattgttt
    19441 tacggcgaca ctgcgaaccc gatcggatac gccgatttgg tgcaacgcct ctacacatac
    19501 agccaagccc aaatccaagc cggacgcggc acaatcctgc gccatatcgt ccgccacagc
    19561 ctcgggctga tgcacggctt gaaaggcgcg cggacttggc ggcgtatgct ttccgacgca
    19621 acgctcttga aagacaacga cggcagcctg attctcgaag cgtggaaaga ggtcgaacgg
    19681 gcaaatacgc gcgaataggg cggggctgta tgtgtgaaat gccgtctgaa ggcttcagac
    19741 ggcatttgtg cgtttgtcgg gcggtgttta gggggtggta atggcgtgtt tcggcacttt
    19801 gtccatatcc cagtgtgcca ccgcccagtc gagcagttcg gcagggcggt cggcttccgg
    19861 tgcttcgggc aggttgaggt aacggaacac ttggcggagg agttgttcgc ggcggtttaa
    19921 atccaatgcg ggtgcgagcg tctgtttcga ccatttctgc ccttgtgcgt tggtcagcag
    19981 cggcaggtgg gcatattgcg gtgtcggaac gcccaaacat tgctgcaaat agatttggcg
    20041 cggcgtagaa acaagcaggt cttgtccgcg gacgatgtgg gtaacgccct gttcggcatc
    20101 gtcggcaacg acggcgagct ggtatgccca gtaaccgtct gcacgaagca ggacgaaatc
    20161 gccgatgtcg cgggcgaggt tttgggcgta accgccgacg atgccgtctg aaaagccgat
    20221 gtcgcggtcg gggacgcgga tgcgccacgc aggctgtttg ccttgcagtg cagggcgttg
    20281 ctgcggattg cggcaacgtc cgttatagac gaatccgtct gcgccgtgga ctgccgcagc
    20341 ctgccagtct ttgcggctgc aatggcaggg atagaccagt ccggcggttt tcagacggca
    20401 tagggtttct tcatacaggg cgtaacggcg gctctgatag gcgacttctc cgtaccactc
    20461 gaatccgaat gcctcaagcg tgtgcaggat atggcttgcc gcccccggca tttcgcgcgg
    20521 cggatcgagg tcttccatgc gaaccagcca ccttccgccg tgtgcgcgtg catcggcata
    20581 ggaagcgacg gcggtcagca gcgagccgat gtggagcagc ccggtcgggc tgggggcgaa
    20641 acgtcctgtg tacatatccg gtacggcccc tttatttaag actattaatc aaagccatta
    20701 tctcatcttt attcagttcc atcccgggtt cttcaagtaa ggttaaatca tatagggcat
    20761 tatattgctc ttcggtagct gaaccatcca taaggccgga cgagaaaaaa tcgaaggctc
    20821 tatctgcgat tctctcatta cttgcatttc tactaaccag tttcatcaat tctgtatata
    20881 ttgtatgggg aggtaccgga tccttaaaaa tcagatctga ataaatttca ttgggtgaaa
    20941 tgatttcgag tgcttttgct atggttctat ttccttttgt gttggcgggt aatgtcgtgc
    21001 attaacttct tgcccattaa tatttttagg gcgaatcctt gatatgccgc actgtgtccg
    21061 gtcaaaaggg cgatgccgtc tgaaagcctt tcagacggca tcggggatga aaagtttaaa
    21121 ccaacggtgc gagcagtttt tcaaacgctt cttcaaactg tttcaaaccg tcttcctgca
    21181 aacgcgttgc caaggtttcg acatcgatgc cgagcgcggc ggtttcggcg agctgcgctt
    21241 gtgcttcttc tacgccttcg gtcagcgtgg ctttggctgt gccgtggtcg ataaaggctt
    21301 tgagcgtggc atcgggaacg gtgttgacgg tgtgcgcgcc gatcaggctg tcaacgtaga
    21361 gcgtgtcggg ataggctggg tttttcacgc cggtagatgc ccataaaagc tgcacgcggt
    21421 ttgcgccttg ggcttccagt gcggcaaatt cgggggcggt gaaatattgt tcccaatctt
    21481 gataggcggc tttggcaagg gcgatggcga ttttgccttt gagccggtcg ggcagtgttg
    21541 tgtccagcgc actgtccaca cgcgagatga agaagctggc gacgacgtgg atatgggcaa
    21601 cgctttgtcc ggctgccaag cgtttggcaa tgccgcgcgc gtaggcggcg taggctttga
    21661 gggtttgggc gcgtgagaac agcagcgtga ggtttacgct gatgccgtct gaaacgaggg
    21721 tttcgagcgc atcgatgcct gcgtcggtgg caggcacttt aatcatcgcg tttttgcacc
    21781 cgatggcggc gtagaggcgg cgcgcttctt ctaccgtgcc ttgcgcgtct ttggacaatt
    21841 cgggcgaaac ttcgaggctg acgaaaccgg ttttgccgcc ggtggattcg tgttcggcaa
    21901 ggcagacgcc gcaggcggca cgcacatcgg caaccgccat cgtttcgtag cgttgtttgg
    21961 gggtcaggtc ttgctgcttg agggcggcaa cctcgtcggc gtaaagcgcg tcgcctgcga
    22021 aggctttttg gaaaatggcg ggattggaag ttacgccgca cacgccttgt ttcaacattt
    22081 gcgccaattc gccgctttgc acgagcgagc gggaaaggtt gtccagccag atttgttgtc
    22141 ctaatgcttt aacgtccgat aaaatagtca tttctgattc ctttggatgg atgtgtatgt
    22201 ttcaaaggct tatgctaccc cgattcggaa attttgggta gttttattac agcaaaggcg
    22261 gatggcaatg gcagaaaacg gaaaatatct cgattgggcg cgcgaagtgt tgcacaccga
    22321 agcggaaggc ttgcgcgaaa ttgcggcgga tttggacgaa aacttcgccc ttgcggcgga
    22381 cgcgttgttg cactgcaaag gcagggtcgt tatcacgggc atgggcaagt cgggacatat
    22441 cgggcgcaaa atggcggcaa ccatggcctc gaccggcacg cctgcgtttt tcgtccaccc
    22501 tgcggaagcg gcacacggcg atttgggtat gattgtggac aacgacgtgg tcgtcgcgat
    22561 ttccaattcc ggtgaaagcg atgaaatcgc cgccatcatt cccgcactca aacgcaaaga
    22621 cattaccctc gtctgcatca ccgcccgccc cgattcaacc atggcgcgcc atgccgacat
    22681 ccacatcacg gcgtcggttt ccaaagaagc ctgcccgctg gggcttgccc cgaccaccag
    22741 caccaccgcc gtcatggctt tgggcgatgc gttggcggtc gttctgttgc gcgcgcgcgc
    22801 gttcacgccc gacgacttcg ccttgagcca ccctgccggc agcctcggca aacgcctact
    22861 tttgcgcgtt gccgacatta tgcacaaagg cggcggcctg cctgccgtcc gactcagcac
    22921 gcccttgaaa gaagccatcg tcagcatgag tgaaaaaggg ctgggcatgt tggcggtaac
    22981 ggacgggcaa ggccgtctga aaggcgtatt caccgacggc gatttgcgcc gcctgtttca
    23041 agaatgcgac aattttaccg gtctttcgat agacgaagtc atgcatacac accctaaaac
    23101 catctccgcc gaacgtctcg ccaccgaagc cctgaaagtc atgcaggcaa accatgtgaa
    23161 cgggcttctg gttaccgatg cagatggcgt gctgatcggc gcgctgaata tgcacgacct
    23221 tttggcggcg cggattgtat agtggattaa caaaaaccag tacggcgttg cctcgcctta
    23281 gctcaaagag aacgattctc taaggtgctg aagcaccaag tgaatcggtt ccgtactatc
    23341 tgtactgtct gcggcttcgt cgcctt
//
LOCUS       DAXIDM010000023        22601 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000023 DAXIDM010000000
VERSION     DAXIDM010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22601
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.023"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(259..2472)
                     /locus_tag="ACFOAE_000740"
     CDS             complement(259..2472)
                     /locus_tag="ACFOAE_000740"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFC6884267.1"
                     /translation="MTAISPIQDTQSATLQELREWFDSYCAALPNNDKKLVLAARSLA
                     EAHYPSDAATPYGEPLPDHFLGAAQMVHELDLLPDAVAATLLADIGRYVPDWNLLVSE
                     RCNSTVAELVKGVDEVQKLTHFARVDSLATPEERAQQAETMRKMLLAMVTDIRVVLIK
                     LAMRTRTLQFLSNAPDSPEKRAVAKETLDIFAPLANRLGVWQLKWQLEDLGFRHQEPE
                     KYREIALLLDEKRTERLEYIENFLNILRGELKKYNVHFEVAGRPKHIYSIYKKMVKKK
                     LSFDGLFDIRAVRILVDTVPECYTTLGIVHSLWQPIPGEFDDYIANPKGNGYKSLHTV
                     IVGPEDKGVEVQIRTFDMHQFNEFGVAAHWRYKEGGKGDSAYEQKIAWLRQLLDWREN
                     MAESGKEDLAAAFKTELFNDTIYVLTPHGKVLSLPTGATPIDFAYALHSSIGDRCRGA
                     KVEGQIVPLSTPLENGQRVEIITAKEGHPSVNWLYEGWVKSGKAISKIRAYIRQQNAD
                     TVREEGRVQIDKQLAKLTPKPNLQELAENLGFKKLDDLYTAVGQGEISNRAIQKACGT
                     LNEPPPVPVSETTIVKQSKIKKGGKNGVLIDGEDGLMTTLAKCCKPAPPDDIVGFVTR
                     DRGISVHRKTCPSFRHLAEQAPEKVLDASWAALQEGQVFAVDIEIRAQDRSGLLRDVS
                     DALARHKLNVTAVQTQSRDLEASMRFTLEVKQVNDLPRVLASLGDVKGVLSVTRL"
     gene            2801..3442
                     /locus_tag="ACFOAE_000741"
     CDS             2801..3442
                     /locus_tag="ACFOAE_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GrxB family glutaredoxin"
                     /protein_id="HFC6884268.1"
                     /translation="MKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGMIG
                     AKQVPVLQKEDGSFMGESLDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRV
                     IKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLERINADLQELENLMDGASD
                     GINGGIGMEDILVFPVLRNLTVVRGIAFPRKTMDYLIGMSEKSGVPLYFDRAL"
     gene            3779..4282
                     /locus_tag="ACFOAE_000742"
     CDS             3779..4282
                     /locus_tag="ACFOAE_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884269.1"
                     /translation="MDFFDFFAQGKYKKIATEQGLDRKYFIFQYIVCNLSAISSFCLM
                     KIIHTYTILYILIAVIGIINGFLLRSKVLSIVKNKQKFLSDMFPLEMPFFFVEYKIPI
                     LARFLNRGMKWLYLPSFFCLVAICFSIYILNEEGGWMPYFACYWFGLCYPVSTYYVFL
                     SRDYKHI"
     gene            4418..5218
                     /locus_tag="ACFOAE_000743"
     CDS             4418..5218
                     /locus_tag="ACFOAE_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HFC6884270.1"
                     /translation="MKKTIFNITKMDCPSEEQLIRMRLKDVSDIYELQFDIAGRCLTV
                     YHDNQDTTILQVLEPLNFDSHIISTEVIVDKIVFNKPDEHLEKRLLYQVLMINFVFFI
                     IECSVGIFANSMGLIADSLDMLADSFVYILALSAIGMTMAYKKRVAFLAGITQIILAL
                     FGVIEVIRRFIGAEQLPNYQLMIGTAFLALIANWLCLYLLSKNQNKEIHIKASMIFTS
                     NDIIINIGVIAAGALTLLTHSSYPDLIIGMIVFVIVLFGARNILKLAK"
     gene            complement(5670..6308)
                     /locus_tag="ACFOAE_000744"
     CDS             complement(5670..6308)
                     /locus_tag="ACFOAE_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HFC6884271.1"
                     /translation="MFQNFDLGVFLLAVLPVLLAITVREVARGYTARYWGDNTAEQYG
                     RLTLNPLPHIDLVGTIIVPLLTLMFTPFLFGWARPIPIDSRNFRNPRLAWRCVAASGP
                     LSNLAMAVLWGVVLVLTPYVGGAYQMPLAQMANYGILINAILFALNIIPILPWDGGIF
                     IDTFLSAKYSQAFRKIEPYGTWIILLLMLTGVLGAFIAPIVRLVIAFVQMFV"
     gene            6563..7405
                     /locus_tag="ACFOAE_000745"
     CDS             6563..7405
                     /locus_tag="ACFOAE_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0031992 - energy transducer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy transducer TonB"
                     /protein_id="HFC6884272.1"
                     /translation="MDKERILTPAVVFSVALLHLAMVALLWQAHKLPVIESGNVIEFV
                     DLGDFGGGDGAPEGAGAPAAPEPQPEPEPPKPVEPPKPVLKPVVTKKADADIQQPKEE
                     PKPEEKPKPEEKPKPEPKPEAKPVPKPAEKPVEKPSEKPAEHPSNASAKADSEQGNGE
                     DKGTGTKGDGTGRGEGSGKGSGGVKGEHGEGAGSSKGNPLRANGSIPRPAYPTLSMEN
                     DEQGTVVLSVLVSPGGHVESVKIVKSSGFSRLDNAARKAAQNGHFQANAWTEFKVPVK
                     FELN"
     gene            7471..8133
                     /gene="exbB"
                     /locus_tag="ACFOAE_000746"
     CDS             7471..8133
                     /gene="exbB"
                     /locus_tag="ACFOAE_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-system energizer ExbB"
                     /protein_id="HFC6884273.1"
                     /translation="MNLKLVFESGDPVLIGVFVLMLLMSIVTWCLVVLRCIKLYRARK
                     GNAAVKRHMRDTLSLNDAVEKVRAVDAPLSKLAQEALQSYRNYRRNEASELAQALPLN
                     EYLVIQIRNSMAQIMRRFDYGMTALASIGATAPFIGLFGTVWGIYHALINIGQSGQMS
                     IAAVAGPIGEALVATAAGLFVAIPAVLAYNFLNRGTKILTQDLDAMAHDLHVRLLNQK
                     DS"
     gene            8136..8570
                     /locus_tag="ACFOAE_000747"
     CDS             8136..8570
                     /locus_tag="ACFOAE_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ExbD/TolR family protein"
                     /protein_id="HFC6884274.1"
                     /translation="MAFGSMNSGDDSPMSDINVTPLVDVMLVLLIVFMITMPVLTHSI
                     PLELPTASEQTNKQDKQPKDPLRLTIDANGGYYVGGDSASKVEIGEVESRLKAAKEQN
                     ENVIVAIAADKAVEYDYVNKALEAARQAGITKIGFVTETKAQ"
     gene            complement(9071..9499)
                     /locus_tag="ACFOAE_000748"
     CDS             complement(9071..9499)
                     /locus_tag="ACFOAE_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01244 family sulfur transferase"
                     /protein_id="HFC6884275.1"
                     /translation="MAILKLDEHLYISPQLTKADAEQIAQLGIKTVICNRPDREEESQ
                     PDFAQIKQWLEQAGVTGFHHQPVTARDIQKHDVETFRQLIGQAEYPVLAYCRTGTRCS
                     LLWGFRRAAEGMPVDEIIRRAQAAGVNLENFRERLDNARV"
     gene            complement(9564..11312)
                     /locus_tag="ACFOAE_000749"
     CDS             complement(9564..11312)
                     /locus_tag="ACFOAE_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M61 family metallopeptidase"
                     /protein_id="HFC6884276.1"
                     /translation="MIHYKITPSPLDHEWHILLTFTQDDDLPIEISLPNWVPGSYLIR
                     DFSRHITSIHASCNGTSMPLEQIAKNRWHAAAVRGEWQIRYTVYAFDLSVRGSFLTTE
                     RGFFDGSCLFLKVEGTETLPHRLELTGIPSEWRIATTLPETGRFVFQAASYAELIDRP
                     VEMGLIEFLDFEAAGIPHTIALSGIYPDFDRNRLVSDIKKICETELAVFSSPAPFQKY
                     LFLLHVGDHIYGGLEHTDSTALLADRHSLPPYGMTDADDTYTTLLGLFSHEYFHAWNV
                     KSIKPAAFVPYDLDKENYTEQLWAFEGITSYYDDLFLARSRTISPESYLNLLAQGITR
                     VQQTRGRLRQTLAESSFTAWNKFYKPDENSPNAIVSYYQKGALAALCLDLIIRNRSNG
                     RHSLDTLMDKLYREWRDTHSGIPEKHWQIRCQEITGLDLEDFFQKALYSTEDLPLAEC
                     LATAGVGLTFLPLPRQHGGGYAEHICPVPSAGDFGARFKQNTDHIVLTHVFNGGSAES
                     AALCPQDKIIALDGYACTDFTAQWARYHVNAKINIHFFRAGILRQTVLTVQAAAADTA
                     ILHITDRNLLDNWLFG"
     gene            11639..13072
                     /gene="ccoN"
                     /locus_tag="ACFOAE_000750"
     CDS             11639..13072
                     /gene="ccoN"
                     /locus_tag="ACFOAE_000750"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045278 - plasma membrane respiratory
                     chain complex IV [Evidence IEA];
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit I"
                     /protein_id="HFC6884277.1"
                     /translation="MDTQTYNYKVVRQFAIMTVVWGIVGMLVGVIVAAQLFAPALDLS
                     NIGPWFHFGRLRPLHTNAVIFAFGGCGLIGTSYYVVQRTCNTRLFGGWLPAFTFWGWQ
                     AVIVAAVVSFPMGWTQGKEYAELEWPIDILITLVWVAYAIVFFGTIAKRKIKHIYVAN
                     WFYGGFILAVALLHIVNNISIPAGLMKSYPVYSGAIDAMVQWWYGHNAVGFFLTAGFL
                     GMMYYFVPKQAARPVYSYRLSVVHFWALIFTYMWAGPHHLHYTALPDWTQSLGMVLSL
                     ILFAPSWGGMINGIMTLSGAWDKLRTDPILKFLIVSLSFYGMSTFEGPMMSIKTVNAL
                     SHYTDWTVAHVHAGALGWVGFVTIGSVYYMIPRLFGKEQMHSTKLVEAHFWIATIGVV
                     LYIAAMWIAGVMQGLMWSSLNDDGTLTYSFVESVKRTMPYYVIRFAGGLLYLSGMCIM
                     AYNVYRTAIGGKAVDAEIPAVSQTQHH"
     gene            13099..13710
                     /gene="ccoO"
                     /locus_tag="ACFOAE_000751"
     CDS             13099..13710
                     /gene="ccoO"
                     /locus_tag="ACFOAE_000751"
                     /EC_number="7.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit II"
                     /protein_id="HFC6884278.1"
                     /translation="MKLQQLAEEKIGVLIVFTLLVVSVGLLIEVVPLAFTKAATQPAP
                     GVKPYNALQVAGRDIYIREGCYNCHSQMIRPFRAETERYGHYSVAGESVYDHPFQWGS
                     KRTGPDLARVGGRYSDEWHRIHLLNPRDVVPESNMPAFPWLARNKVDVDATVANMKAL
                     RKVGTPYSDEEIAKAPEALANKSELDAVVAYLQGLGLALKNVR"
     gene            13715..13885
                     /locus_tag="ACFOAE_000752"
     CDS             13715..13885
                     /locus_tag="ACFOAE_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcoQ/FixQ family Cbb3-type cytochrome c oxidase
                     assembly chaperone"
                     /protein_id="HFC6884279.1"
                     /translation="MDINGIRALFTVWIFICFLLVLYIVFNRRNKKNYDNAANSIFDE
                     NQDAQDKKSENR"
     gene            13909..14820
                     /gene="ccoP"
                     /locus_tag="ACFOAE_000753"
                     /pseudo
     CDS             13909..14820
                     /gene="ccoP"
                     /locus_tag="ACFOAE_000753"
                     /inference="COORDINATES: protein motif:HMM:TIGR00782.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c oxidase, cbb3-type subunit III"
     gene            14896..15240
                     /locus_tag="ACFOAE_000754"
                     /pseudo
     CDS             14896..15240
                     /locus_tag="ACFOAE_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582195.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c5 family protein"
     gene            15628..17037
                     /locus_tag="ACFOAE_000755"
     CDS             15628..17037
                     /locus_tag="ACFOAE_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="HFC6884280.1"
                     /translation="MDTQIKTEADNQSNRRYLTVWRWHFYAGLLVMPFLTLLAVTGLG
                     MLLFANITGKEGERIHVVPQATVQPLSVQAEAARSAVNPETSSVVQYIAPRADDMVAV
                     FRVNNEGKATMVAVDPYTAKVVSTMPRNQGWYYAMDEIHSDMMLGSTGDYLLETAASL
                     TIIMIISGLYLWWVKRRGIKAMLLPPKGRARSWWRNLHGAFGTWVSLILLLFCLSGIA
                     WAGIWGGKFVQAWSQFPAGKWGVEPNPVSVVPTHGEVLNDGKVKEVPWILELTPMPVS
                     GTTVGKDGINPDEPMTLETVDRFAREIGFKGRYQLNLPKGEDGVWTLSQDSMSYDMIS
                     PFADRTVHIDQYSGKILADIRFDDYNPFGKFMAASIALHMGTLGWWSVLANVLFCLAV
                     IFIGISGCVMWWKRRPSGAAGMVPPAQKIKLPVWWAMAVPLLLIALLFPTALLAIAVI
                     WLLDTLLLSRIPVLRKWFK"
     gene            17138..20347
                     /gene="recC"
                     /locus_tag="ACFOAE_000756"
     CDS             17138..20347
                     /gene="recC"
                     /locus_tag="ACFOAE_000756"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HFC6884281.1"
                     /translation="MFYLYQSNRLETLAALFAHIQKVKPLKSALQPEQIIVQSQGMRR
                     YLNTCLARDLGVAANLSFSLPAGLTWKLMKKLIPGIPELSPFAPEVMRWRLLDLFRSE
                     AFRNTAEFEDVRNVLQDYLGSGESADYQLAGQLADIFDQYLVYRPQWIDAWQQGRILG
                     LGDDEIWQSKLWRYLDDGRQSAPHRVALWEKLLASLSSDKLPERYFVFGISTMAPMYL
                     QLLHKLSEHCDVFVFALNPSGMYWGNVIEAAQILKGGGDPDLTQAGHPLLASLGKQGR
                     DFFDFLNEMEIEGETPVFEEGSRDTLLHALQTDIQNLKMPSETAGSVGTDDGSIRIVS
                     AHSPLRELQILKDKLLKILHEHPDWQPYDIAVLTPNIESYTPFIEAVFGQAQPGAQAL
                     PYSVSDVKISRRQPLFHALSCLFDLLESRFEVDKVLVLLETAPVLRRFGLTEDDLPLL
                     HDMVADLNVHWGLDGEMRGGTDQLFTWKQAVERMILGWMLPEGGNPMWQDVSAWYADV
                     NQTAMFGRFAAFLETLSDIVRIWRQPATVGEWVARCRDLLEILFQAGPDDQKAVQNLE
                     NEWVKWQEESTLAGFVGQLPQQTVIRHIRHFLDSESEAGFLRGGITFCSMVPMRSLPF
                     KVICLLGLNDGDFPRNTKAAVFDLIAKHPAKGDRARRDDDRYLFLEALISAREILYLS
                     YIGRDIRKDEELAPSSLLGELIDTVAAMTGTNSRQLAQNWIEQHPLQAFSRRYFQEGG
                     RSDGIFGTRTDYAAALGQTPEPPQPFFDQSVENAEPVAEIGQDEFIRFWLNPVKVWLQ
                     QQLAWSEPHIGEAWEPAEPFEPQHADQIAETYIEARREGRDFAQTAARIGAESLLPSG
                     ELGRLWQQDFQTAAKQIDTAVLNSPKLPPLSYAIPSDGQILKGSLSNLYQCGQVFYAY
                     GKPNAPQRIAFLLEHLIFCAVMPSEAETRQTFIVQSGETEILAEIAQDRALQLLSEWM
                     AFFNIGQNRPLPFFAKTSLATAEAFAQKQDWEAALKKAQTAYHGNKVSKGQKDYTEVA
                     LVFGNASQNPLEQPLFENLVRLLADTFAAAEKKEEAGAA"
     gene            complement(20417..21985)
                     /gene="mtrF"
                     /locus_tag="ACFOAE_000757"
     CDS             complement(20417..21985)
                     /gene="mtrF"
                     /locus_tag="ACFOAE_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041421321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family antimetabolite efflux transporter
                     MtrF"
                     /protein_id="HFC6884282.1"
                     /translation="MSQTDTQRDGRFLRTVEWLGNMLPHPVTLFIIFIVLLLIASAAG
                     AYFGLSVPDPRPVGAKGRADDGLIHVVSLLDADGLIKILTHTVKNFTGFAPLGTVLVS
                     LLGVGIAEKSGLISALMRLLLTKSPRKLTTFMVVFTGILSNTASELGYVVLIPLSAII
                     FHSLGRHPLAGLAAAFAGVSGGYSANLFLGTIDPLLAGITQQAAQIIHPDYVVGPEAN
                     WFFMVASTFVIALIGYFVTEKIVEPQLGPYQSDLSQEEKDIRHSNEITPLEYKGLIWA
                     GVVFVALSALLAWSIVPADGILRHPETGLVSGSPFLKSIVVFIFLLFALPGIVYGRVT
                     RSLRGEQEVVNAMAESMSTLGLYLVIIFFAAQFVAFFNWTNIGQYIAVKGATFLKEVG
                     LGGSVLFIGFILICAFINLMIGSASAQWAVTAPIFVPMLMLAGYAPEVIQAAYRIGDS
                     VTNIITPMMSYFGLIMATVIKYKKDAGVGTLISMMLPYSAFFLIAWIALFCIWVFVLG
                     LPVGPGAPTLYPAP"
     gene            22318..22530
                     /locus_tag="ACFOAE_000758"
     CDS             22318..22530
                     /locus_tag="ACFOAE_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884283.1"
                     /translation="MKNEIQKIMDKYNPWHEDDFESYEDIAKDVSLMTDKTFIEHYLL
                     EVYSEENGHFDQENIHAMIGEIKNAI"
BASE COUNT         5669 a         5187 c         5979 g         5766 t
ORIGIN      
        1 aaaaaccagt acggtgttgc ctcgccttgc cgtactattt gtactgtctg cggcttcgtc
       61 gccttgtcct gatttttgtt aatccactat agtttaaagc tttgtttctt aagtcctcag
      121 agtatgccat ggttagacct tcaaagttga gtattgtact attttgtttt taattgacta
      181 tgcaacaaaa aatagcaaac cccgtcaatc aaaatgccgt ctgaagcgtt atacggcttt
      241 cagacggcat ttttgtattt aaagccgggt aacgctcaat acgcctttga cgtcgccgag
      301 gctggcgagg acgcgcggga ggtcgttgac ctgtttgact tcgagcgtga accgcatact
      361 ggcttccaag tcgcgggact gggtttgcac ggcggtaacg ttgagtttgt ggcgggcgag
      421 cgcgtcggat acgtcgcgca aaagcccgga gcggtcttgg gcgcggattt cgatatcgac
      481 ggcaaacact tgtccttcct gcaacgccgc ccagcttgcg tccagcactt tttcaggtgc
      541 ttgttcggcg aggtgtcgga aagaggggca ggttttgcgg tgtaccgaaa tgccgcgatc
      601 gcgggtaacg aagccgacaa tgtcgtcggg cggcgcgggt ttgcagcatt tggcaagcgt
      661 ggtcatcaaa ccgtcttcgc catcaatgag cacaccgttt ttgccgcctt ttttgatttt
      721 ggactgtttg acgatggtgg tttcgctgac gggtacgggc ggaggttcgt tcagcgtgcc
      781 gcaggctttt tggatggcgc ggttggaaat ttcgccttgt ccgacggcag tgtagaggtc
      841 gtcgagtttt ttgaagccga ggttttcggc aagctcttgc aggttgggct tgggcgtgag
      901 tttggcaagc tgcttgtcga tttggacgcg gccttcttcg cgcacggtgt cggcgttttg
      961 ctggcggatg taggcgcgga ttttactgat tgccttgccg gatttgaccc agccttcgta
     1021 cagccagttg acggaaggat gcccttcttt ggcggtaatg atttcgacgc gctgtccgtt
     1081 ttcaagcggg gtggacagcg gcacgatttg cccttcgact ttcgcgcccc ggcagcggtc
     1141 gccgatgctg ctgtgcaggg cgtaggcgaa gtcgatgggt gtcgcgcccg taggcaggga
     1201 aaggactttg ccgtgcgggg ttaaaacgta aatcgtgtcg ttgaacagct cggttttgaa
     1261 ggcggcggcg aggtcttcct tgccgctttc cgccatattt tcgcgccagt ccaaaagttg
     1321 gcgcaaccag gcgatttttt gctcgtaggc ggaatcgcct ttgccgcctt ctttgtaacg
     1381 ccagtgcgcg gcgacaccga attcgttgaa ttggtgcata tcgaaggtgc ggatttgcac
     1441 ttccacacct ttgtcttcgg gaccgacgat gacggtgtgc aaacttttat agccgttgcc
     1501 tttcgggttg gcgatgtagt cgtcgaactc gccggggata ggctgccaaa ggctgtggac
     1561 aatgcccagc gtggtgtaac actcggggac ggtatcaacc agaatccgca cggcgcggat
     1621 gtcaaagagg ccgtcgaagc tgagtttttt cttcaccatt tttttgtaaa tggagtagat
     1681 gtgtttcggg cggccggcga cttcgaaatg gacattgtat ttcttgagtt caccgcgcag
     1741 gatgttgagg aagttttcga tgtattcgag gcgttcggtg cgtttttcgt ccaaaagcag
     1801 cgcgatttcg cggtattttt cgggctcttg atggcggaag cccaaatctt cgagctgcca
     1861 tttgagctgc cacacgccca aacggttggc gagcggggcg aagatgtcga gggtttcttt
     1921 ggcgacggcg cgtttttcgg ggctgtcggg ggcgttgctt aaaaattgca gggtgcgcgt
     1981 acgcatcgcc agtttgatta acacgacgcg gatgtcggta accatcgcca gcagcatttt
     2041 ccgcatggtt tccgcttgct gggcgcgttc ttctggcgtg gcgaggctgt ccacccgggc
     2101 gaagtgggtg agtttctgca cttcgtccac acctttgacc agctcggcga cggtactgtt
     2161 gcagcgttcg gaaaccaata ggttccaatc ggggacgtag cgtccgatgt cggcaagcag
     2221 ggtggcggcg acggcatcgg ggagcaggtc gagttcatga accatttgcg ccgcgccgag
     2281 gaagtggtcg ggcagcggct cgccatacgg cgtggcggca tcggaggggt aatgtgcttc
     2341 cgccagcgaa cgggcggcta agacaagttt tttatcgttg ttcggcagcg cggcgcagta
     2401 gctgtcgaac cattcgcgca attcttgcag agtcgcgctt tgcgtgtctt gaatcgggct
     2461 gatggcggtc atgatggggt cttccgttcc gataaaaacg agtttattgt aacagcttga
     2521 gacctttgca ataacatagg ttactaaaat tttatgctca atctcatttt caaaatgcaa
     2581 aacttttctg atttttccta ctttttgctc aatattagga aggttttagg caattgaaaa
     2641 ttttttggcg catttttatg cgtcaaattt cgttaacaga ctatttttgc aaaggtctca
     2701 gcttatttat ttacggtgca taggcgggaa gataaacttg tttcgggtgg cgcggggtgt
     2761 taaggtagcc ggtaccgaca ggttgacgag gaatattttg atgaaactgt atatttacga
     2821 ccattgcccg ttttgcgtgc gtgcgcggat ggctgccggg ctgtttggcg cggacgttga
     2881 agaagccgtg ctggcaaacg acgacgaggc aacgccgatc ggtatgatcg gtgcgaaaca
     2941 agtgcccgtc ctgcaaaaag aagacggttc gtttatgggc gagagtttgg acattgtgcg
     3001 gcatttcgac cgcgaagacc gtctgaaaga cgaagtccgc cccgagatac gggcgtggct
     3061 ggacaaggtg ggcggataca acgacaaact ggtgcagccg cgcgtgatca aaatcgggct
     3121 gcctgaattt gcaacgccgg aagcggtgaa atattttaca gacaaaaaag agaaaagcat
     3181 cggcagcttt tccgccaatt tgaataaaac cgcccaatac ctcgaacgga taaacgcaga
     3241 tttgcaagag ttggaaaatt tgatggacgg tgcttcagac ggcatcaacg gcggaatcgg
     3301 tatggaggat attttggttt tccccgtttt gaggaatctg accgtggtgc gcggcatcgc
     3361 gttccctcgg aagacgatgg attatttaat cggtatgagt gaaaaatcgg gcgtgccact
     3421 ttatttcgac agggcattgt aaaagtggct gttattaact gacagatgaa ggaggttcta
     3481 ccctatttga ggtaaactct atttaccatt ggccgaaata ccagtgctta tctccaagac
     3541 gaccttccca atcccttttg cctcttaaaa agaagtgact agtgtgtaaa gttatagttc
     3601 cttttatagc tttccaataa aattaaagta tttaaaagct tgtttagttc taatttgtta
     3661 atttctgtat ctaaataatg ttcagaatag tattattttt taaataaacc atgaatagta
     3721 cttcacattg tttgtcgtat tatttagctt ttaaatttct aatgtgaaag atagtttaat
     3781 ggatttcttt gatttttttg cgcaaggtaa gtataaaaaa attgcaactg aacaaggttt
     3841 agaccgtaaa tattttatat tccaatatat cgtatgtaat ttatctgcca tttcttcttt
     3901 ttgtctaatg aagattattc atacttatac tattctctat atattaatag ctgtcatcgg
     3961 tattattaat ggctttctct tgagaagcaa ggttctatct atagtaaaaa ataaacaaaa
     4021 gtttttatct gacatgtttc ccttggaaat gcctttcttt tttgtagaat acaaaatacc
     4081 tatcttggct agattcttga ataggggaat gaaatggctt tatctcccaa gttttttctg
     4141 tttagttgcg atttgtttct caatatatat ccttaatgaa gaaggggggt ggatgcctta
     4201 ttttgcctgc tattggtttg gactttgtta tccagtaagc acttattacg tttttttatc
     4261 cagagattat aaacatatct aaactattat gcgtggcggt acttccaaag gtaaatttta
     4321 acctaatcaa tttactcaaa ccatccaaaa attaccaagc agcaatataa acacagattt
     4381 atttgagcca acctgatcaa aacaaggaac taaatagatg aaaaagacca tttttaacat
     4441 taccaaaatg gactgcccgt ccgaagaaca gctcattcgc atgcgtttaa aagatgtgtc
     4501 tgatatttat gaattacagt ttgatattgc tgggcggtgc ttaaccgtct atcacgataa
     4561 tcaagataca acgattttac aagtacttga accgcttaat tttgatagtc atatcatttc
     4621 caccgaagtg attgttgata agatagtgtt taacaagcct gatgagcact tagaaaaaag
     4681 attattatat caagtgctca tgattaactt tgtgtttttt atcatagagt gttcggttgg
     4741 tatttttgct aattctatgg ggctgattgc tgatagtcta gatatgctgg cggacagctt
     4801 tgtctatata ttggcgctat cagccattgg tatgacgatg gcgtataaaa aacgtgtggc
     4861 atttttggcg gggataacgc agataatatt ggcgttattt ggggtgatag aagtgattag
     4921 gcgttttatc ggtgctgagc agctgcccaa ttatcaactg atgattggca cggcattttt
     4981 ggcattgatt gcaaactggc tgtgcttata tctactgagc aaaaatcaaa ataaagaaat
     5041 ccatatcaaa gccagcatga tttttacatc caatgacatt atcatcaata tcggtgtgat
     5101 agcggcggga gcattgacgt tattgactca ttctagctat cctgatttaa tcattggcat
     5161 gattgtcttt gtcattgtac tatttggtgc cagaaatatt ttaaaattgg caaaataatt
     5221 cctttcacca gcaaaggagt ttttatgcaa atatcggtca aagctaccta catacgtggc
     5281 agtacttcca aaaacttgat tttttaaaat gtggttaatg cgagtttgtt tatctggtat
     5341 ttgattggtc aagccttcat ccaagcgttt gacgatttca cgcaaaaata cccctgattt
     5401 acacacaggg tctaagaatg tcgcctttgg atttgaccaa atctcagacg gcaataaatc
     5461 cagcatttga ttggcaagtt ttggcgatgt gaaaacctca tcattagaca gactggagtt
     5521 tcttaatcag tgtttcagtt aatgaaaggt attatcatgc aacttggttc taataatgat
     5581 gaaaaaaata agattacact acaggaaaac gcggcagggc aatatgtcct gccgcgtttt
     5641 ctggagcgtt tatgccgtct gaaagccagt cagacgaaca tctgcacaaa cgcaatcacc
     5701 agccgcacaa tcggtgcaat aaacgcaccc aaaaccccgg tcagcataag cagcaggata
     5761 atccacgtcc cataaggttc gattttgcgg aacgcttgcg aatatttcgc cgacaggaag
     5821 gtgtcgatga aaatgccgcc gtcccaaggc aggatgggga tgatgttgag cgcgaacaga
     5881 atcgcattga tcagaatacc gtagtttgcc atttgagcca acggcatctg atacgccccg
     5941 ccgacatacg gagtcagcac caaaaccacg ccccacagaa cagccatcgc cagattcgac
     6001 agcgggccgg acgcggcaac gcaacgccag gcaaggcgcg ggttgcggaa gttgcgcgaa
     6061 tcgataggaa tcggacgcgc ccagccgaac aggaagggcg tgaacatcaa agtaagcagc
     6121 ggtacgatga ttgtgccgac caaatcgata tggggcaggg ggttcagtgt cagcctgccg
     6181 tattgttcgg cagtgttgtc tccccagtag cgcgccgtat agccgcgcgc cacctccctg
     6241 acggtaatgg cgagcagcac gggcaggacg gcaagcagaa acacgcccaa atcaaaattt
     6301 tgaaacatgg ttttcctttg aacagatgtg gtgtgcagcc cgaaacggct gacagacaga
     6361 agcggcaata tatcatctaa cctgatttta ttggaataag aaatcagacg gaatcatttt
     6421 ttctgccggc ccgttatctg atgatttgct gtaatacagc gtttaaacac ggtttgcctg
     6481 tgaacggaac agacattcat atgaccaaaa attgtaaaaa taggttgcaa ataggaattg
     6541 ttgctattat tatgcccgaa ttatggataa agaacgaatt ttaacccccg cagtcgtgtt
     6601 ttccgtcgca ctgctgcatt tggcaatggt ggcattgctt tggcaggcgc acaagctgcc
     6661 cgtgatagag tcaggcaatg ttattgaatt tgtcgatttg ggtgattttg gcggagggga
     6721 cggtgcaccc gaaggcgcag gtgcgcctgc tgcgcctgag ccgcaacctg agcctgagcc
     6781 gcccaaacct gtcgagccgc ccaagccggt tttgaagccg gtggttacga aaaaggcgga
     6841 tgcggatatt cagcagccta aggaagagcc gaaacctgaa gaaaagccga aacccgaaga
     6901 aaaaccgaaa ccagagccta agccggaagc gaagcctgtc ccgaaaccgg cggaaaaacc
     6961 ggtcgagaag ccgtctgaaa aacctgccga acatcccagc aatgcttctg ccaaagcaga
     7021 cagcgagcag ggtaatgggg aagataaggg aaccggtacc aaaggagacg gaacggggcg
     7081 cggagaaggc agcggtaaag gtagcggcgg tgtcaaaggc gaacacgggg aaggagccgg
     7141 cagcagcaaa ggcaatcctt tacgcgccaa cggcagcatt ccgcgcccgg cttatcccac
     7201 gctttctatg gagaatgacg agcagggtac ggttgttttg agcgttttgg tttctccggg
     7261 cggtcatgtc gagtccgtta aaatcgtgaa aagcagtggt ttttctcggt tggacaatgc
     7321 ggcacgcaag gcggcgcaaa acgggcattt tcaagccaat gcctggacgg agtttaaagt
     7381 ccccgtcaag tttgaattga attaggcggt tgccgcagcg gtttgcggca gcttggatgt
     7441 ttgattggtt ttttcagtgt tggaatcatt atgaatttga aattagtatt tgaatcgggc
     7501 gatcccgtcc tgatcggtgt gtttgtgttg atgctgttga tgagtatcgt aacgtggtgt
     7561 ttggttgtct tgcgctgcat caagctgtat cgggcgcgca aagggaatgc cgccgtcaaa
     7621 cggcatatgc gcgatacttt gtcgctgaac gacgcggtcg aaaaagtgcg cgccgtcgat
     7681 gcgcctttgt ccaaactggc gcaagaggca ttgcagtctt accgcaacta ccgccgaaac
     7741 gaagcgtccg aactggcgca ggctttgccg ttgaacgagt atttggtcat tcaaatccgc
     7801 aacagtatgg cgcagattat gcgccggttt gattacggga tgaccgcgct tgcctccatc
     7861 ggcgcgaccg cgccgtttat cgggctgttc ggcacggttt gggggattta ccacgccctg
     7921 atcaatatcg ggcaaagcgg gcagatgagt attgcggcgg ttgccggccc gattggcgag
     7981 gcactggtgg cgacggcggc gggtttgttc gtggcgattc cggcggtgtt ggcatacaac
     8041 ttcctcaatc gcggcacaaa aatactgacc caggatttgg atgcgatggc gcacgatttg
     8101 cacgtccgcc tgcttaatca aaaggatagc tgattatggc atttggttcg atgaattccg
     8161 gcgacgattc tccgatgtcc gacatcaacg ttacgccgtt ggtggacgtg atgctggtgt
     8221 tgctgattgt gtttatgatt actatgccgg tgctgacgca ttccatccct ttggaactgc
     8281 cgaccgcgtc cgagcagaca aacaagcagg acaaacagcc taaagacccc ctgcgcctga
     8341 cgattgatgc gaacggcggc tattatgtcg gcggggattc tgcaagcaaa gtggaaatcg
     8401 gggaagtgga aagccgtctg aaagccgcca aggagcagaa tgaaaacgtg attgtggcga
     8461 ttgcggcaga caaggcggtg gaatacgatt atgtaaacaa agctttagaa gccgcccgtc
     8521 aggcaggaat caccaaaatc ggttttgtaa ccgaaaccaa ggcgcaataa agttcgacgc
     8581 ttgaacgaat gccgtctgaa agtctttcag acggcatttc ttatgtttaa tcagctatat
     8641 atagttgatt aaaacaaaaa tgagacgaca gagcgccgtc tccatttctg cgcaggcggg
     8701 aatacaaaca tctgattttt cttttatttt caaacattac tgaaatgggt aagtctggag
     8761 tcctgcctgc gcgagaataa tgaaaatgtg catttctaat ttttatagtg gattaacaaa
     8821 aatcaggaca aggcaacgaa gccgtagaca gtacaaatag tacggaaccg attcacttgg
     8881 tgcttcagca ccttagagaa tcgttctctt tgagttaagg cgaggcaacg ccgtactggt
     8941 ttttgttaat ccgctatacc cactgtaaaa acggagaagg acagaggacg gcagtaaggt
     9001 ttgccgtcct ctttttcaag ttgcggtgga atgccgcttg aaggtgtggt ttaaacgttt
     9061 cggcttgtaa tcagacgcgg gcgttgtcca gccgctctct gaagttttcc aaatttacgc
     9121 ctgccgcttg ggcgcggcgg atgatttcgt caaccggcat accttctgcc gctcggcgga
     9181 agccccacag gagggagcag cgcgtaccgg tccggcaata ggcaaggacg ggatattcgg
     9241 cttgtccgat gagttggcgg aaggtttcga catcgtgttt ttggatgtcg cgtgcggtaa
     9301 cgggttggtg atggaatcca gtaacgcctg cttgttccag ccactgtttg atttgggcga
     9361 agtcgggttg cgattcttct tcgcggtcgg ggcggttgca gatgacggtt ttgatgccca
     9421 gttgcgcgat ttgttccgca tcggctttgg tcagttgcgg agaaatatag aggtgttcgt
     9481 caagtttcag aatggccatt ttgtttcctt tactttgcgg ttgtttttca gacggcattt
     9541 tgtgtgcaat gccgtctgaa agtttaaccg aacaaccagt tgtccaacag gttccggtct
     9601 gtgatatgta ggatggcagt atccgctgcc gctgcctgaa ccgtcaagac ggtttgacgc
     9661 aatatgccgg cacggaagaa gtggatattg atttttgcat tgacgtggta tcgggcccat
     9721 tgtgcggtaa agtcggtgca ggcataaccg tctaaagcaa tgattttgtc ttgcgggcac
     9781 agtgccgcag attccgcgct gccgccgttg aagacatggg tcaggacgat gtggtcggtg
     9841 ttttgtttga aacgtgcgcc aaaatcgcct gccgacggga cggggcagat gtgttctgcg
     9901 tatccgccgc cgtgttgtcg gggaagcggc aggaaggtca gtcccacgcc tgcggttgcc
     9961 aggcattcgg caagcggcaa atcttcggta ctgtataacg ctttttggaa aaaatcttcc
    10021 aaatccaagc cggtaatttc ctgacagcgg atttgccagt gtttttccgg aatacccgag
    10081 tgtgtgtccc tccactcccg atagagtttg tccattaacg tatcgagaga atgtctgccg
    10141 ttgcttcggt tgcgtattat cagatcaagg cacaatgcgg caagcgcgcc tttctggtag
    10201 tagctgacga tggcgttggg gctgttttca tccggtttgt aaaatttgtt ccacgcggta
    10261 aaactcgatt ccgccaaggt ctgcctcaaa cggccgcggg tttgttgtac gcgcgtaatg
    10321 ccttgtgcca gcaggtttaa ataagattcg ggcgagatgg tgcggctgcg tgccaaaaac
    10381 aaatcgtcgt aataggatgt aatgccttcg aatgcccata gttgttcggt atagttttct
    10441 ttgtcgaggt cataagggac gaacgcggca ggtttgatgg atttgacgtt ccacgcgtga
    10501 aaatattcgt gggagaaaag tccgagcaat gtggtgtagg tatcgtcggc atcggtcata
    10561 ccgtacggcg gaaggctgtg gcggtcggcg agcagggcgg tgctgtcggt gtgttccaaa
    10621 ccgccgtaaa tatggtcgcc gacgtggagc aggaacaaat atttttgaaa cggggcaggg
    10681 gaggaaaaca ccgccagttc tgtttcgcag atttttttga tatccgaaac cagcctgttg
    10741 cggtcgaaat cgggatatat gccgcttaag gcaattgtgt gcggaatgcc tgccgcctca
    10801 aaatctaaaa attcaatcaa gcccatctcg acaggtcggt caatcaattc ggcataagat
    10861 gccgcctgaa agacaaacct ccctgtttcc ggcagcgttg tggcaatacg ccattcggac
    10921 ggaatacccg tcaattccaa gcggtgcggc agcgtttccg ttccttcgac tttcaaaaac
    10981 aggcacgatc cgtcaaaaaa accgcgttct gtcgtcagga aagaacctcg aaccgacaaa
    11041 tcgaatgcat atacggtgta gcggatttgc cactcgccgc gtacggcggc ggcatgccag
    11101 cggtttttgg caatttgttc gagcggcatg gacgtgccgt tacaggatgc atggatagaa
    11161 gtgatgtggc gggaaaaatc ccgaatcaga tagctgcccg gaacccagtt tggcaggctt
    11221 atttctatag gaagatcatc atcttgtgtg aatgtcagca ggatgtgcca ctcgtggtcg
    11281 agaggggacg gggttatttt ataatgaatc ataactatca aatatatcgt taaacgggat
    11341 ggattaaata cctttaaaat gcagcttaac ctacatcaat aaagtgccac aaaaagggaa
    11401 aattggaaac aaaagcaatg gcggtcgggt tgtaatttat tataacaata tgatttatat
    11461 gtaataaaaa acagattaag caaagggctc gccggcggcg cgaatgtaat tccgcttggc
    11521 gtaataaggc agatatgtta aatttagaaa aaattacgct tgcccggatt gcaccttaaa
    11581 caggctgcgg aagcggcagg ataaaaatct ttattcccat aaattcatgg agactctcat
    11641 ggacacacaa acttacaact acaaagtggt gcgccagttc gccatcatga ctgtagtttg
    11701 ggggattgtg ggtatgttgg tcggcgttat cgtcgccgcc cagctttttg ctcctgccct
    11761 cgacttgtct aatatcggac cttggttcca cttcggccgc ctgcgtccgc tgcacaccaa
    11821 tgcggttatt ttcgcatttg gcggttgcgg cctgatcggc acatcatact acgttgtcca
    11881 acgtacttgt aatacccgtc ttttcggcgg ttggctgccg gcatttacct tttggggctg
    11941 gcaggcggta atcgttgccg ccgtcgtcag cttccctatg ggttggaccc aaggtaagga
    12001 atatgccgaa ctggaatggc cgatcgatat tctgattact ttggtttggg tggcttacgc
    12061 catcgtattc ttcggtacga ttgccaaacg taagattaaa catatttacg ttgccaactg
    12121 gttctacggc ggctttattt tggcggtcgc acttttacac atcgtcaaca atatcagcat
    12181 cccggccggt ttgatgaagt cataccccgt ctattccggt gcgattgatg ctatggttca
    12241 atggtggtac gggcataatg ccgtgggctt cttcctgact gccggcttct tgggtatgat
    12301 gtactatttc gtacccaaac aagcagcccg ccccgtttac tcctaccgcc tgtccgtcgt
    12361 tcacttctgg gcgttgattt tcacctatat gtgggcgggt ccgcaccatc ttcactacac
    12421 tgcgctgcct gactggacgc aatctttggg tatggttctg tctttgattc tgttcgcacc
    12481 ctcttggggc ggtatgatta acggcatcat gaccttgtcc ggcgcgtggg acaaactgcg
    12541 tacagacccg attcttaaat tcctgattgt atccttgtcc ttctacggta tgtctacctt
    12601 tgaaggcccg atgatgtcga ttaaaacggt caatgcattg agccactata cggactggac
    12661 cgtcgcgcac gttcatgcgg gtgcgttggg ctgggtaggc tttgtaacca tcggttccgt
    12721 ctattacatg attccccgtc tgttcggcaa agaacagatg cacagcacca agctggtaga
    12781 agcacatttt tggattgcga ccatcggcgt ggttctgtat atcgctgcca tgtggattgc
    12841 cggtgtgatg cagggtttga tgtggagttc tttgaacgat gacggtacgc tgacctactc
    12901 gtttgtcgaa tccgtaaaac gcaccatgcc ttactacgtg atccgttttg caggtggttt
    12961 attgtatctg agtggtatgt gcattatggc gtacaacgtg taccgcacag ccatcggtgg
    13021 taaagcagtc gatgccgaaa tccctgcggt ttcccaaaca cagcaccact aaaatactaa
    13081 gaaagatagg ctaccaaaat gaaattacaa caattggctg aagaaaaaat cggcgttctg
    13141 attgtgttca cgctgcttgt agtcagtgtc ggtctgttga ttgaagttgt gcccttggcc
    13201 tttaccaagg cggcaacaca gccggcaccg ggcgtgaagc cttacaatgc cttgcaggtt
    13261 gccggacgcg atatttacat ccgtgagggc tgttacaact gccactctca aatgattcgt
    13321 ccgttccgtg cggaaaccga gcgttacggt cattactctg ttgccggaga gtcggtttac
    13381 gaccatcctt tccaatgggg ttccaaacgt accggtcctg atttggcacg tgtaggcggc
    13441 cgctattccg acgaatggca ccgtatccac ctgctgaatc cccgtgatgt cgtgcctgag
    13501 tccaatatgc cggcattccc atggcttgca cgcaataaag tcgatgtcga tgcaaccgtt
    13561 gccaacatga aggctttgcg taaagtaggt actccttaca gtgatgagga aattgcgaaa
    13621 gcgcctgagg ctttggcaaa caaatccgag ctggatgctg tagtcgccta tctgcaagga
    13681 ttgggtctgg ctttgaaaaa cgtaaggtaa catcatggat attaacggta ttcgcgctct
    13741 tttcacggta tggatcttta tctgtttcct gttggtactc tatatcgtct tcaacaggcg
    13801 gaataagaaa aactacgata atgccgcaaa cagcattttt gatgaaaacc aagatgcgca
    13861 agataagaaa agcgaaaacc gttaatattg tgataacgga gcaaaacaat gaacacaaca
    13921 tcccaattta ccagtaattt ctggaatata tatattgcag ttattgtctt actgagcttt
    13981 atcgctttgg cttggctgct gctgtctcaa aatgttgtca aacgtccgaa gaagggcgaa
    14041 gaagtacaaa ctacgggtca tgagtgggac ggcattgccg aatacgacaa tccgctgccc
    14101 cgctggtggt tttggctgtg tgttttgacg tggctgttcg gtatcggtta tttggttatg
    14161 tatccgggtg tcggcgacta caaaggtctg ctgaaatgga ccagccataa ccaatatgaa
    14221 aaagaggtca aaaaagccga tgagcaatac ggcaaactgt atgccaagtt tgcggatatg
    14281 ccgattgaaa aagtggcaaa agaccctcaa gccaagcaaa tcgcccaaaa cctgtttaac
    14341 acttattgta tccagtgcca cggctctgat gctaaaggct ctaaaggttt tccgaatctg
    14401 accgatagcg attggttgtg gggcggtgat cccgataaaa tccacgagac catcgaaaaa
    14461 ggccgtgttg cgactatgcc tgcctggggt cctgctttgg gcgaagaagg cgtgaaagac
    14521 gttgcccatt atgtgatgtc cctttcaaaa cccgaaggtc agtatgatga ggaacgtgcc
    14581 gcgcgcggac aagccttgtt cagcggtccg cctgccaact gtttcacttg ccacggcgat
    14641 aagggacaag gtatccaagg tttgggtccg aacctgactg atgacgtgtg gttgtggggc
    14701 ggtacgcaaa aatccattat cgaaaccatt accaacggtc gcagcagcca aatgcccgct
    14761 tggggacatt tcttggataa agacaaactg catattatga ctgcttatgt atggggtctt
    14821 tccgataaag acggtaaagc tccggtgaaa aaagccgagc ctgcaccgac tcccgcaccg
    14881 gcggcagaac ccgcagcctc tgctcctgca gaagcagcac aagccgcgtc cgaagccaaa
    14941 cctgccgcag cagaacctaa agctgaggaa aaagccgcac ctgctgccaa agcggacggc
    15001 aaataggttt atgaaaccgt ttgtgccgcc tgccatggca atgcgattcc gggtattccc
    15061 catgtaggca tcaaagccga ttgggccgac cgcatcaaaa aaggcaagga cacgttgcac
    15121 aaacacgcga tcgaaggttt caatacgatg cccgcaaaag gcggtcgcgg cgatttgagc
    15181 gatgatgagg ttaaagctgc ggttgactat atggtcaacc agtcaggcgg caaattctaa
    15241 cttgactgag tttccgatat tatcggttat gaaaatccag attcagtatt gaatctggat
    15301 tttttgtttt aacgggcatc cggttttaaa cgcagactga gacctttgca ataacatagg
    15361 ttactaaaat tttatgctca atctcatttt caaaatgcaa aacttttctg atttttccta
    15421 ctttttgctc aatattagga aggttttagg caattgaaaa ttttttggcg catttttatg
    15481 cgtcaaattt cgttaacaga ctatttttgc aaaggtctca gactgcctat ttgttgtaat
    15541 gaattttgac tttagtcata aagaattagt ctttattgtt tataatcgcg catcatcacg
    15601 atagccctat tttcaaaagg acgatttatg gatacacaaa tcaagactga agccgacaat
    15661 cagagcaacc ggcgttatct gaccgtttgg cggtggcatt tttatgccgg tctgctggtt
    15721 atgccttttc ttaccctgct tgccgttacg ggtttgggta tgctgctgtt tgccaatatt
    15781 accggtaagg agggcgagcg gattcatgtt gtgccgcagg caacggtaca acctctgtct
    15841 gttcaggcgg aagcggcacg cagtgccgtt aatccggaaa cttcgtccgt cgttcagtat
    15901 attgcgccgc gtgccgatga tatggttgcc gtgttccgtg tcaacaatga gggtaaggca
    15961 acgatggtcg cggtcgatcc ttatacggca aaagtggtca gtaccatgcc gcgcaatcag
    16021 ggttggtatt acgcgatgga tgaaatccac agcgatatga tgctcggttc gacaggtgat
    16081 tatcttttgg aaacggctgc atcgctgacg attatcatga taatcagcgg tttgtacctt
    16141 tggtgggtga aacggcgcgg catcaaggcg atgctgctgc cgccaaaagg cagggcgcgt
    16201 tcttggtggc ggaatctgca cggcgcgttt ggaacttggg tgtcgttgat tttactgttg
    16261 ttctgcctgt cgggtattgc ttgggcaggt atttggggcg gcaagttcgt gcaggcttgg
    16321 agtcagttcc cggcaggcaa atggggtgtc gaaccgaacc ctgtttcagt cgtgccgacc
    16381 catggcgagg tattgaacga cggcaaggtt aaggaagtgc cgtggatttt ggagcttacg
    16441 cctatgcctg tttcagggac gactgtgggc aaagacggca ttaaccccga cgagccgatg
    16501 acattggaaa ccgtcgaccg ttttgcgcgg gaaatcggtt tcaaagggcg ttatcagttg
    16561 aatttgccca aaggcgagga cggcgtatgg actttgtcgc aagactctat gagttacgat
    16621 atgattagtc cgtttgccga ccgcacggtg catatcgacc agtacagcgg caagattctt
    16681 gccgacatcc gttttgatga ttacaacccg ttcggcaaat ttatggcggc aagcattgcg
    16741 ctgcatatgg ggactttggg ctggtggagc gtgttggcga acgtcttgtt ctgccttgcc
    16801 gtgattttta tcggcatcag cggctgcgtg atgtggtgga aacgccgtcc gtccggagcg
    16861 gcgggcatgg ttccgccggc gcaaaaaatc aagctgcccg tctggtgggc aatggcggtg
    16921 ccgctgctgc tgattgcatt gcttttcccg accgcgctgc ttgccattgc cgtgatttgg
    16981 ctgttggata ccttgctgct gtcgcggatt cctgttttga ggaaatggtt taaatgacca
    17041 aatgccgtct gaaaggttca gacggcattt tgtttgaagg cggacggggg aaaggctata
    17101 taatcccgaa tacttttccg caacttttgt cgaaatcatg ttttatctgt atcaatccaa
    17161 ccgtcttgaa acgctggcgg cactgtttgc ccacattcaa aaagtcaaac cgctgaaatc
    17221 ggctttacag cccgaacaga ttattgtgca gagtcagggg atgcgccgct acctcaatac
    17281 ctgcctcgcc cgcgatttgg gcgtggcggc gaatttgtcg ttcagcctgc ccgccggtct
    17341 gacgtggaag ctgatgaaaa aactgattcc cggcattccg gaactcagcc cgtttgcgcc
    17401 tgaagtgatg cgctggcggc tgttggattt gttccgcagc gaggcatttc ggaatacggc
    17461 agaatttgaa gatgtgagga atgtgctgca agactatctg ggcagcggcg aatcggcaga
    17521 ttaccagctt gcgggacagc ttgcggacat attcgaccaa taccttgtct atcgtccgca
    17581 gtggatagac gcgtggcagc agggcaggat actcggtttg ggcgacgatg aaatctggca
    17641 gtccaaactg tggcgttacc tcgacgatgg caggcagagc gcgccgcacc gtgtcgcgtt
    17701 gtgggaaaag ctgttggctt ctttgagcag tgataagctg cccgagcgtt atttcgtgtt
    17761 cggcatttcc acgatggcgc cgatgtattt gcaacttttg cacaagctgt ccgaacattg
    17821 cgacgtgttc gtgttcgcac tcaatccgag cgggatgtat tggggcaacg tcatcgaagc
    17881 ggcgcaaatc ctcaaaggcg gcggcgatcc cgatttaact caggcagggc atccgctgct
    17941 cgcctcattg ggcaagcagg ggcgggactt tttcgacttt ttgaacgaaa tggaaataga
    18001 aggagaaacg ccggtgtttg aagaaggcag ccgcgatacg cttttgcacg ccctgcaaac
    18061 cgatattcaa aacctgaaaa tgccgtctga aacggcggga agcgtcggta cggatgacgg
    18121 ctcgatacgc atcgtctccg cgcacagtcc tttgcgcgaa ttgcagatac tcaaagacaa
    18181 gctgttgaaa attctgcatg aacatcccga ttggcagccg tacgacatcg ccgtattaac
    18241 cccgaatatc gaatcctata cgccttttat cgaagccgtg ttcggacagg cgcagcccgg
    18301 tgcgcaggca ttgccgtatt ccgtttcaga cgtgaaaatc agccgccgac aaccgctgtt
    18361 tcatgctttg tcatgcctgt tcgacttgtt ggaaagccga tttgaagtcg ataaagtgct
    18421 tgtgctttta gaaaccgcac ccgtgttgcg ccgtttcgga ctgaccgagg acgatttgcc
    18481 gcttttgcac gatatggttg ccgatttgaa cgttcactgg ggtttggacg gagaaatgcg
    18541 cggcggcacg gatcagctgt tcacctggaa gcaggcggta gaacgcatga tattgggctg
    18601 gatgctgccc gaaggcggca atccgatgtg gcaggatgtc agcgcgtggt atgccgacgt
    18661 gaatcaaacc gccatgttcg gacgttttgc cgccttcctc gaaaccctgt cggatattgt
    18721 acggatatgg cggcaacctg cgacggtcgg cgaatgggtg gcgcgttgcc gggatttgct
    18781 tgaaatattg ttccaagccg ggcccgatga ccaaaaggca gtccaaaacc tcgaaaacga
    18841 atgggtcaaa tggcaggaag agagtactct ggctgggttc gtcggacagt tgccgcaaca
    18901 aaccgttatc cgccacatcc gccatttcct cgacagcgaa agcgaggcag gctttttacg
    18961 cggcggcatc accttttgca gtatggtgcc gatgcgcagc ctgccgttca aagtcatctg
    19021 cctgttgggt ttgaacgacg gagattttcc ccgcaatacc aaagccgccg tattcgacct
    19081 gattgccaaa catcccgcca aaggcgaccg agcccgtcgc gacgacgacc gctacctgtt
    19141 ccttgaagct ctcatcagcg cgcgcgaaat cctgtatttg tcctacatcg ggcgcgatat
    19201 ccgcaaagac gaagagcttg ccccgtcttc gctgttgggc gaactcatcg acacagttgc
    19261 cgccatgacc ggcacaaaca gccgccaact tgcacaaaat tggatagaac agcatccgct
    19321 gcaagccttc tcgcgccgat atttccaaga aggcggacgt tcagacggca tattcggcac
    19381 gcgtaccgac tacgccgccg cgctcggaca aacgcccgaa ccgccacaac cctttttcga
    19441 ccaatccgta gaaaacgccg aacctgttgc cgaaatcgga caggacgaat ttatccgttt
    19501 ctggctcaac cccgtcaaag tatggcttca gcagcagctt gcgtggagcg aaccccatat
    19561 cggcgaagcc tgggaaccgg ccgaaccctt cgagccgcaa cacgccgatc aaatcgccga
    19621 aacctacatc gaagcacggc gcgaaggacg ggattttgcc caaaccgccg cccgtatcgg
    19681 ggcagaaagc ctgctgccgt cgggagagtt gggcagactt tggcagcagg acttccaaac
    19741 cgctgccaaa caaatcgaca cggcggtttt aaacagcccc aaactgccac cgctttcata
    19801 cgccataccg tcggacgggc aaatcctgaa aggcagtttg agcaatttat accaatgcgg
    19861 acaagtgttt tacgcctatg gcaaacccaa tgcgccgcaa cgtatcgctt ttctgctgga
    19921 acacctgata ttttgcgccg ttatgccgtc tgaagccgaa acgcggcaaa cctttatcgt
    19981 ccaatccgga gaaaccgaaa tattggcgga aatcgcgcaa gacagggcat tgcagctatt
    20041 gtcggaatgg atggcatttt tcaatatcgg gcaaaaccgc ccgctgccgt tttttgccaa
    20101 aacctcgctt gccaccgccg aagcgtttgc ccaaaaacaa gattgggaag ccgccctgaa
    20161 aaaagcccaa accgcctacc acggcaacaa agtcagcaaa gggcagaaag actataccga
    20221 agtcgccctc gtgttcggca acgcaagcca aaacccgctc gaacagcccc tgtttgaaaa
    20281 cctcgtccgt ctgcttgccg acacgtttgc cgcagcggaa aaaaaggaag aggccggagc
    20341 agcctgacgg gatggaaagg caaatgccgt ctgagaacag caaaaaggtt ttcagacggc
    20401 attttgttta tcgtgtttaa ggtgcgggat acaaagtggg tgcgccggga ccgacgggca
    20461 gacccaaaac aaatacccaa atgcagaata aggcaatcca cgcaatcaag aagaaagcgg
    20521 aatacggcaa catcatagaa atcagcgtac ccacgcccgc atcttttttg tatttgatca
    20581 ccgtcgccat aatcagcccg aaataactca tcatcggcgt aataatattg gtaacggaat
    20641 caccgatgcg gtaagcggct tgaatgactt cgggcgcgta gccggccaac atcagcatag
    20701 ggacgaaaat cggcgcagtt accgcccatt gcgcggaggc ggagcctatc atcagattga
    20761 taaaagcaca aattaaaata aaaccgataa acaacacgct gccgcccaag ccgacttctt
    20821 ttaagaacgt cgccccttta acggcaatat attgcccaat attcgtccaa ttaaaaaatg
    20881 cgacaaactg tgcggcaaaa aagatgatga ccaaataaag ccccagagta ctcatcgatt
    20941 cggccatcgc attaacgact tcctgttcgc cgcgcaaact tcgggttacc cggccataaa
    21001 caatgcccgg cagtgcaaac aacaagaaaa taaaaacaac aatcgatttt aaaaacggcg
    21061 aaccggaaac caatcctgtt tcaggatgac gcaaaatacc gtcggcaggg acgatgctcc
    21121 aagccaatag ggcggataag gcaacaaaca ccacgccagc ccaaattaat cctttatatt
    21181 ccaaaggcgt gatttcattg gaatgtcgaa tgtctttttc ttcttgtgac aaatctgatt
    21241 gataagggcc caattgcggt tcgacgattt tttcagtaac aaaataacca atcaaagcaa
    21301 tcacaaacgt actggctacc ataaaaaacc agttggcttc agggcctacg acgtagtcgg
    21361 gatggatgat ttgcgccgcc tgttgggtga tgcctgccaa gagcggatcg attgtgccta
    21421 agaacagatt ggccgaataa ccgcccgaaa cgccggcgaa agccgcagcc agaccggcaa
    21481 gcggatggcg gccgagggaa tgaaagatga tggcggacaa agggattagg acgacatagc
    21541 ccaattcaga agcggtatta gataaaatcc ctgtaaaaac aaccataaaa gtagtgagtt
    21601 tgcgtggaga ttttgtgagc aataagcgca ttaatgcgga aatcaagccc gatttttccg
    21661 caatccccac gcccaataaa gaaaccaaca ccgttcccaa cggcgcgaaa ccggtgaaat
    21721 ttttaacggt atgcgtcagg attttgatca aaccgtcagc atcgagcagg ctgacaacgt
    21781 gaatcaaacc gtcatcggca cgtcctttcg caccaacagg gcgcggatcg gggacggata
    21841 gtccgaaata cgcaccggcg gcagaggcaa tcagcaataa cacaatgaaa ataataaaaa
    21901 gcgtaaccgg gtgcggcaac atattgccca gccattcgac tgtgcgtaaa aatcgtccgt
    21961 cccgttgcgt atcggtttga ctcatctgct tctccttaaa aaaatatatt gagtgcatta
    22021 aatttttgaa tgtaacatga agtgttttgt aagcaaacta aaataatcgt atatgtatat
    22081 aaccgtaata gattaaaaca gaaaatgccc acatcgttat tctcataaag gcggtaatcc
    22141 gaaaacttga cgttaaagcc ttatcaggaa tgactggaac tcaaaaaaac ggattcccgc
    22201 ctgcgcggga atgacgggat tttcggtttt tgtttgcaag aatgccggag aagaacgcag
    22261 tttacatttt gaatggtatt gttattaatt gtaaataaat attggaaggt aaatgatatg
    22321 aaaaatgaaa ttcaaaaaat catggacaaa tataatccat ggcatgaaga tgattttgag
    22381 tcgtatgaag acattgccaa agatgtatcg ctgatgacag ataaaacgtt cattgaacat
    22441 tatttgttag aagtttattc agaagaaaac ggacattttg accaagagaa tatccatgcg
    22501 atgatagggg aaattaaaaa tgcaatttag tgaatatgag acctttgcaa aaatagtctg
    22561 ttaacgaaat ttgacgcata aaaatgcgcc aaaaaatttt c
//
LOCUS       DAXIDM010000024        22253 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000024 DAXIDM010000000
VERSION     DAXIDM010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22253
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.024"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..99
                     /locus_tag="ACFOAE_000759"
                     /pseudo
     CDS             1..99
                     /locus_tag="ACFOAE_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            complement(120..1034)
                     /locus_tag="ACFOAE_000760"
     CDS             complement(120..1034)
                     /locus_tag="ACFOAE_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC6884284.1"
                     /translation="MDAVQLKSFVAVAHEGNLTQAAKRLFLSQPAVSAQIKALEEYVG
                     TPLFRRTGKGMVLTRAGEILLPEAESLLQYKHKLEHFAKTLAGDYSEETSLGIIHPID
                     SAKLVALTDNIGQTAPKTRLHIQYGMSGEILSRIQHKTLHGGFILGNAAQRGIRSVFL
                     QNLTYALICPQSQYPHLTRSLPQSLQECVWIEMSGVSGSRKHLHQFWRSNRLSPKKQI
                     LCDYPQTIIDLVAGGIGVAMVPGNKAEAAAKEGAGVAIIESCRHSMPLNFIYAEEYED
                     NPHVSLLLECIEKVWGVQAVQPPVVSDN"
     gene            1290..2759
                     /locus_tag="ACFOAE_000761"
     CDS             1290..2759
                     /locus_tag="ACFOAE_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3360 family protein"
                     /protein_id="HFC6884285.1"
                     /translation="MEKHNGTYRDLHRPASEFATRDEYLEHELQIMQPKRWRPNLPFR
                     DYRFEWEDLIPAMAGTIGKVVMVGAVAAAFAAPLGLPDSFVLENVRYELLIAAAFILL
                     VSGFFLPGANLPGTHGPLIPMIPIVVSAGGHPLAFGISIAVLGLLMALFRGGSIMAKL
                     TSNGVCGGLLLYLGFIGTTGQVKKLFSWAGGFNMPYIAFTVIIVTIVMYALLEHWKKR
                     WLAVPLGCLIAGVVAFTLGAPFEFHTAPGLPPMSPAYWWGENSGWHLGLPTAESFLVV
                     FPFAVLAVAMWSPDFLGHQVFQKISYPEKTDKVLMNIDDTMTSCSVRQAVGSILGGAN
                     FTSSWGTYIVPASIAKRPIPGGAVLTAVLCIIAGLWGYPMDLAIWQPVLSVALVVGVY
                     LPLLEAGMEMTRKGKTTQSAAIVVFSSALVNPVFGWALTMLLDNLGLIGCKERSAQLG
                     FAGRVLIPAVGFLILCVAMGAVGMLPGIPPFLEHFKSLG"
     gene            3010..3381
                     /locus_tag="ACFOAE_000762"
     CDS             3010..3381
                     /locus_tag="ACFOAE_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884286.1"
                     /translation="MNKTLSILPVAILLGGCAAGGGNTFGSLDGGTGMGGSIVKMAVG
                     SQCRAELDKRSEWRLTALAMSAEKQAEWENKICACVAQEAPERMTGNDVMQMLAPSTR
                     NQALAALTAKTVSACFKHLYR"
     gene            3454..4863
                     /gene="thrC"
                     /locus_tag="ACFOAE_000763"
     CDS             3454..4863
                     /gene="thrC"
                     /locus_tag="ACFOAE_000763"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HFC6884287.1"
                     /translation="MKYISTRGETAHKPFSEVLLMGLAPDGGLMLPEHYPQIGRETLD
                     KWRGLAYPELAFEIMRLFVTDIPEDDLRDILNRTYTEAAFGTKEITPVRTLSDGIKIQ
                     ALSNGPTLAFKDMAMQFLGNAFEYVLNKEGKKLNILGATSGDTGSAAEYALRGKKGVN
                     VFMLSPDGKMSAFQRAQMYSLQDGNIHNIAVKGMFDDCQDIVKAVQNDAAFKEKYHIG
                     TVNSINWGRIVAQVVYYFAGYFKATQSNDEQVSFCVPSGNFGNVCAGHIAKQMGLPIR
                     RLIVATNENDVLDEFFKTGAYRPRNSAHTYVTSSPSMDISKASNFERFVFDLMDRDPQ
                     EINTLWAEVAAGKGFDLRFALEKVGGKYGFTSGKSTHPDRLATIRQVYEQDQELIDPH
                     TADGVKVAREVREEGETVVCLETALAAKFDATIREAVGDAAIPRPAALEGLENLPQRV
                     QTVPNSADAVKGIIEQTLA"
     gene            4909..5703
                     /locus_tag="ACFOAE_000764"
     CDS             4909..5703
                     /locus_tag="ACFOAE_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884288.1"
                     /translation="MTLPMQETRFSILLDELAAKQKAAIAPHLLADGSKVWIRKAGRH
                     NARWRYALLGMVARYLKLGVLKPVPSLGGEPAIATESKRLYELRAAGIAVPELLAVRK
                     NALMFGNLEGIPLDTQIRQEAEAGKADAWLAGLEAIARVHKKQQFLSQAFARNMMSDG
                     KNISFLDFEDDPSEVLTIAQCQARDWLCYIHSTALILKNGGLLEAAAEKWGGVLSDQP
                     AEIQKLIAATVKPILPIRRLEHPRWGRDALRLAASISLISLADMPP"
     gene            5891..6667
                     /locus_tag="ACFOAE_000765"
     CDS             5891..6667
                     /locus_tag="ACFOAE_000765"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP reductase"
                     /protein_id="HFC6884289.1"
                     /translation="MAAFNTQKVLSVHHWTDAYFTFTCTRDESLRFENGQFVMVGLMV
                     DGKPLMRAYSVASANWEEHLEFFSIKVQDGPLTSRLQHLKVGDDVLISKKPTGTLVAG
                     DLNPGKHLYLLSTGTGIAPFLSITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKEL
                     PEHEYLGDLVKEKLIYYPIVSREEFEHHGRLTDLMVSGKLFEDIGLPKINPQDDRAML
                     CGSPAMLKDTCKVLDDFGLTVSPKTGVRGDYLIERAFVDQ"
     gene            complement(7325..9796)
                     /locus_tag="ACFOAE_000766"
     CDS             complement(7325..9796)
                     /locus_tag="ACFOAE_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFC6884290.1"
                     /translation="MKKTCFHCGLDVPENLHLTVRYENEDRETCCAGCQAVAQSIIDA
                     GLGSYYKQRTADAQKTELPPQEILDQIRLYDLPEVQSDFVETHGGTREAVLMLGGITC
                     AACVWLIEQQLLRTDGIVRIDLNYSTHRCRVVWDDGKIRLSDILLKIRQIGYTAAPYD
                     AQKIEAANQKERKQYIVRLAVAGLGMMQTMMFALPTYLYGGDIEPDFLQILHWGGFLM
                     VLPVVFYCAVPFYQGALRDLKNRRVGMDTPITVAIIMTFIAGVYSLATNAGQGMYFES
                     IAMLLFFLLGGRFMEHIARRKAGDAAERLVKLIPAFCHHMPDYPDTQETCEAAVVKLK
                     AGDIVLVKPGETIPVDGTVLEGSSAVNESMLTGESLPVAKMPSEKVTAGTLNTQSPLI
                     IRTDRTGGGTRLSHIVRLLDRALAQKPRTAELAEQYASSFIFGELLLAVPVFIGWTLY
                     ADAHTALWITVALLVITCPCALSLATPTALAASTGTLAREGILIGGKQAIETLAQTTD
                     IIFDKTGTLTQGKPAVRRISLLRGTDEAFVLAVAQALEQQSEHPLARAILNCRISDGS
                     VPDIAIKQRLNRIGEGVGAQLTVNGETQVWALGRASYVAEISGKEPQTEGGGSAVYLG
                     SQSGFQAVFYLTDPLKDSAAEAVRQLAGKNLTLHILSGDRETAVAETARALGITHYRA
                     QAMPEDKLEYVKALQKEGKKVLMIGDGINDAPVLAQADVSAAAAGGTDIARDGADIVL
                     LNEDLRTVAHLLDQARRTRQIIRQNLIWAGAYNIIAVPLAVLGYVQPWIAALGMSFSS
                     LAVLGNALRLHKRGKMPSEKMPSEQ"
     gene            complement(9793..10971)
                     /gene="hflX"
                     /locus_tag="ACFOAE_000767"
     CDS             complement(9793..10971)
                     /gene="hflX"
                     /locus_tag="ACFOAE_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009347253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFC6884291.1"
                     /translation="MTGRTGRNGSTQAQPERVMLVGVMLDKDGTGSSATRLNGFQTAL
                     AEAVELVKAAGGDSVRVETAKRDRPHTALFVGTGKAAELSEAVAADGIDLVVFNHELT
                     PTQERNLEKILQCRVLDRVGLILAIFARRARTQEGRLQVELAQLSHLAGRLIRGYGHL
                     QSQRGGIGMKGPGETKLETDRRLIAHRINALKKQLANLKKQRALRRKSRESGTIKTFA
                     LVGYTNVGKSSLFNRLTKSGIYAKDQLFATLDTTARRLYISPECSIILTDTVGFVSDL
                     PHKLISAFSATLEETAQADVLLHVVDAAAPNSGQQIEDVENVLQEIHAGDIPCIKVYN
                     KTDLLPSEEQNTGIWRDAAGKIAAVRISVAENTGIDALREAIAEYCAAAPNTDETEMP
                     "
     gene            complement(10976..12256)
                     /locus_tag="ACFOAE_000768"
     CDS             complement(10976..12256)
                     /locus_tag="ACFOAE_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HFC6884292.1"
                     /translation="MKSLFIRLLLLGSAAGVFYHTQNQSLPAGELVYPSAPQIRDGGD
                     ALHYLNRIRAQIGLHKLAHAPVLENSARRHARYLTLNPEDGHGEHHPDNPHYTAQKLT
                     ERTRLAGYLYNGVHENISTEEEAAESSDSDIRTQQRQVDGLMSAIYHRLSLLDRHTDE
                     AGAAFVRENGKTVLVFNQGNGRFERHCAQGRNQPEAGRKYYRNACHNGAVVYTDEAMP
                     AQELLYTAYPVGNGALPYFHGERPDPVPEYEITGNPASIDFSEAAGKITMKSFKLYQG
                     KNEIRPVRVLTAGNDPNGRLTAYQFALFPLKPLEYGTLYTAVFDYVRNGRRAQAKWQF
                     RTRKPDYPYFEVNGGETLAVRKGEKYFIHWRGRWCLEACTRYTYRQRPGSRLSIGRHK
                     AGGIVFSVDGMAGSRITLAPEGETERGVTLYLQD"
     gene            12258..12386
                     /locus_tag="ACFOAE_000769"
     CDS             12258..12386
                     /locus_tag="ACFOAE_000769"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884293.1"
                     /translation="MPSSRRGNGVFYQNGKLANAVSDCRLPNRQTFPRADAEPDAV"
     gene            complement(12409..13134)
                     /locus_tag="ACFOAE_000770"
     CDS             complement(12409..13134)
                     /locus_tag="ACFOAE_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFC6884294.1"
                     /translation="METQNKPTVTDIDRPILVPPGGHKKVLLHSCCAPCSGEVMEAML
                     ASGIDYTIYFYNPNIHPHKEYMLRKEENVRFAEKFGIPFIDKDDDYENDRKEWFAKAK
                     GMEFEPERGIRCTMCFDMRFEKAAQYAHEHGFPVFTSSLGISRWKNMNQINDCGRRAA
                     APYDDVVYWDFNWRKGGGSARMIEISKRENFYQQEYCGCAYSLRDSNAHRKSQGRIPI
                     KLGVLYYGDESTQYEPAPIRVDK"
     gene            complement(13207..13884)
                     /gene="radC"
                     /locus_tag="ACFOAE_000771"
     CDS             complement(13207..13884)
                     /gene="radC"
                     /locus_tag="ACFOAE_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFC6884295.1"
                     /translation="MSIKQWPEGERPREKLLERGAAALSDAELLAILLRVGTRGMSAV
                     DLARYLLQEFGSLGRLMSAEVGKLSAYKGMGTASFTQFAVVREIGRRILAEELQESIV
                     LSDPDTVADYLRFHLGQEKVEVSVALLLNRQNQLIAVRELSRGTVAENTIYIREIVKL
                     ALDEYADSLIIAHNHPGGSPEPSQEDIMFTRRLAQAMSLVDVSLLDHFIVTAQTVRSF
                     RQLGLMP"
     gene            complement(14007..15356)
                     /gene="gshA"
                     /locus_tag="ACFOAE_000772"
     CDS             complement(14007..15356)
                     /gene="gshA"
                     /locus_tag="ACFOAE_000772"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HFC6884296.1"
                     /translation="MKLPVMSPEHSAQLQAFEAKILSNHAKIEAWFRTQWNAHRPPFY
                     GSVDIRNAGYKISSIDMNLFPGGFNNLNPNFIPLAAVAAQDAVQRACETAKSVLIIPE
                     NHTRNTFYLQNVYALGEILCSAGYEVRLGSLNPEVTEPTEFETALGDKILLEPLLRTR
                     DRVHLADGFSPCVVLLNNDLSAGIPDILKGISQTVLPPLHGGWTTRRKTNHFGAYNQV
                     TAEFAKLIGIDEWQINPYFEKIGGLDFQGREGEDALAEAVERVLAKIQAKYDESGITD
                     KPFVIVKADAGTYGMGVMSVKSADEVRGLNRKNRNKMAKVKEGLEVSEVIVQEGIYTY
                     ETLNGAVCEPVVYMMDRFVIGGFFRVHEGRGADENLNAGGMVFVPLSNSIPTGNGDNS
                     QEAPEACKRVFEQWDSLGMPRSEKDCDVDNEHNRLYVYGVMARLSLLAASIELEETA"
     gene            15616..17025
                     /gene="leuC"
                     /locus_tag="ACFOAE_000773"
     CDS             15616..17025
                     /gene="leuC"
                     /locus_tag="ACFOAE_000773"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HFC6884297.1"
                     /translation="MTAQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEG
                     LKMAGRKLWRIDSVVSTADHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPF
                     MDKGQGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCI
                     TAKKSKSMLIAVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAVEFGGEAIRSLSMEGR
                     MTLCNMAIEAGARSGMVAVDQTTIDYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFD
                     KEYRFNAEDIEPQVTWGTSPEMVLDISSKVPNPAEETDPVKRSGMERALEYMGLEAGT
                     PLNEIPVDIVFIGSCTNSRIEDLREAAAIAKDRKKAANVQRVLIVPGSGLVKEQAEKE
                     GLDKIFIEAGFEWREPGCSMCLAMNADRLTPGQRCASTSNRNFEGRQGNGGRTHLVSP
                     AMAAAAAVTGRFTDIRMMA"
     gene            17122..17376
                     /locus_tag="ACFOAE_000774"
     CDS             17122..17376
                     /locus_tag="ACFOAE_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884298.1"
                     /translation="MNKLFITALSALALSACAGTWEGAKQDTARNLDKTQAAAERAAE
                     QTGNAVEKGWDKTKEAVKKGGNAVGRGISHLGGKIENATE"
     gene            17438..18079
                     /gene="leuD"
                     /locus_tag="ACFOAE_000775"
     CDS             17438..18079
                     /gene="leuD"
                     /locus_tag="ACFOAE_000775"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HFC6884299.1"
                     /translation="MKAFTKITAIVAPLDRSNVDTDAIIPKQFLKSIKRSGFGPNAFD
                     EWRYLDHGEPGMDNSKRPLNPDFSLNQPRYQGAQILLTRKNFGCGSSREHAPWALDDY
                     GFRAVIAPSFADIFFNNCYKNGLLPIVLTEEQVDRLFKEVEANEGYQLSIDLAEQTLT
                     TPGGETFTFDITEHRKHCLLNGLDEIGLTLQHADEIHAFEEKRRQSQPWLFNG"
     gene            18249..19518
                     /locus_tag="ACFOAE_000776"
                     /pseudo
     CDS             18249..19518
                     /locus_tag="ACFOAE_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
     gene            19534..20265
                     /locus_tag="ACFOAE_000777"
                     /pseudo
     CDS             19534..20265
                     /locus_tag="ACFOAE_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229413.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0009036 - type II site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0090304 - nucleic acid metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NgoBV family restriction endonuclease"
     gene            20299..21369
                     /gene="leuB"
                     /locus_tag="ACFOAE_000778"
     CDS             20299..21369
                     /gene="leuB"
                     /locus_tag="ACFOAE_000778"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HFC6884300.1"
                     /translation="MTKHIAILRGDGIGPEIVAETVRVLDKLIAQGLDAGYEYAPLGG
                     EAYDEYGHPYPEFTQNLCRKADAVLLGAVGSPQYDNLDRPLRPERGLLAIRKDLNLFA
                     NLRPAVLYPELANASTLKPEIVAGLNILIVRELTGDIYFGEPRGIRVLENGEREGYNT
                     MKYSESEIRRIAHVAFQSAQKRSKKVCSVGKANVLETTELWREIFEEIGKQYPDVELS
                     HMYVDNAAMQLVRAPKQFDVIATGNIFGDILSDEASMLTGSIGMLPSASLDENGKGLY
                     EPSHGSAPDIAGQNKANPLATILSLAMLLRYSLNDEARAQQVENAVQKVLQQGLRTSD
                     IYEEGTKLVSCSEMGDAVLAAL"
     gene            21532..22095
                     /locus_tag="ACFOAE_000779"
     CDS             21532..22095
                     /locus_tag="ACFOAE_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HFC6884301.1"
                     /translation="MKKIIFAALAAAAVGTASAATYKVDEYHANARFAIDHFNTSTNV
                     GGFYGLTGSVEFDQAKRDGKIDITIPVANLQSGSQHFTDHLKSADIFDAAQYPDIRFV
                     STKFNFNGKKLVSVDGNLTMHGKTAPVKLKAEKFNCYQSPMEKTEVCGGDFSTTIDRT
                     KWGVDYLVNVGMTKSVRIDIQIEAAKQ"
BASE COUNT         5348 a         5859 c         5798 g         5248 t
ORIGIN      
        1 ggcatttcca aagggcattt taagccgtat ttgagagaat gcggatggcg ttttcagtgt
       61 tttcagcgtg ataaaattca aatttctatt ttaaaacaat cagcaaagca ggatttattt
      121 cagttgtccg agacaacggg cggctgcacc gcctgcactc cccatacttt ttcaatgcac
      181 tcgagcagga gtgagacgtg gggattatcc tcgtattctt ccgcataaat gaaattgagc
      241 ggcatactgt ggcggcacga ttcgataata gccacgcccg cgccttcttt tgccgccgct
      301 tcggctttgt ttcccggcac cattgccaca cctataccgc ctgcaaccaa atcgataatg
      361 gtttgggggt agtcgcacaa gatctgtttt ttgggtgaga gccggttgct gcgccaaaac
      421 tggtgcaggt gcttcctact tccggacacg cccgacattt ctatccatac gcattcttgc
      481 aggctctgcg gaagggagcg ggtcagatgg ggatattggc tttgcgggca aatcagcgcg
      541 taggtcaggt tttgcaggaa tacgctgcgg atgccgcgtt gggcggcgtt gccgagtata
      601 aagccgccgt gcagggtttt gtgttggatg cgcgagagga tttcgccgct cattccgtat
      661 tggatgtgca ggcgcgtttt gggggctgtt tgaccgatat tgtccgtcag cgcgacgagt
      721 tttgccgaat cgatggggtg gataatgccc aaactggtct cttccgaata atcgcctgcc
      781 agcgttttgg caaaatgctc cagcttgtgt ttgtattgca gcagggattc cgcttcgggc
      841 aacagtattt cgcccgcccg cgtcaatacc atgcctttcc ccgtgcgcct gaacagcggc
      901 gtgccgacat attcttcaag ggctttaatt tgggcagaaa cggcaggctg ggaaaggaaa
      961 agtcgtttgg cggcttgggt aaggttgccc tcgtgcgcga cggcgacaaa tgattttaat
     1021 tgtacggcat ccatatatcc ctccttgtgc ggatgttttc tatatttgtg caatcgaaat
     1081 cttttaggtg gattgttgct gaaaattaac tttttaatca agtggtttgt aaattgtatc
     1141 agttttccgg atgatggtta tcaaaaaaaa agattggttt tattgcctgt ttgggcttta
     1201 aatggggtta cggcttccga acgcagcccg tatcaaaaag aaaagtcatg cgcccctttt
     1261 acgaggcgcg atatataagg aggaaggtta tggaaaaaca taatgggact tatcgggatt
     1321 tgcaccgtcc ggcttcggaa tttgcgacgc gggacgaata tttggaacat gaattgcaga
     1381 ttatgcaacc aaaacgctgg cggcccaacc tgccctttcg cgattaccgc ttcgagtggg
     1441 aggatttgat tcctgcgatg gcggggacga ttggaaaagt ggtgatggtg ggggcggtgg
     1501 cggcggcgtt tgccgcacct ttggggctgc ctgacagctt tgtactggaa aatgtgcgct
     1561 atgagctttt aatcgccgcc gcgtttatct tattggtatc gggctttttt ctgcccggcg
     1621 ccaacctgcc cggtacgcac gggccgctga ttccgatgat tcccatcgtt gtgtcggcag
     1681 gcgggcatcc tttggcgttc ggcatttcga ttgcggtttt aggtctgctg atggctttat
     1741 ttcgcggcgg cagtattatg gcgaagctga caagcaacgg cgtatgcggc ggattattac
     1801 tctatttggg ctttatcggc acgacggggc aggtaaaaaa attgttttcg tgggcaggcg
     1861 gttttaatat gccctacatc gcttttaccg tcattattgt aacgattgtg atgtacgctt
     1921 tgttggagca ttggaaaaaa cgctggttag ccgtgccttt gggatgcttg attgccggtg
     1981 tggtggcatt tacattgggt gcgccgtttg agtttcacac cgcccccggc ctgcctccaa
     2041 tgagtcctgc ttattggtgg ggtgaaaaca gcggctggca tctggggttg ccgacggcag
     2101 aaagtttttt ggttgtcttt ccatttgcgg tattggctgt tgcaatgtgg tcgcccgatt
     2161 ttttaggaca tcaagtgttc caaaaaatca gctatccgga aaaaaccgat aaggtattga
     2221 tgaatataga cgacaccatg acaagttgtt ctgtccgtca agcagtgggt tctattttag
     2281 ggggtgcaaa ttttacctct tcttggggaa cttatatcgt accggcatcg attgccaaac
     2341 gccccattcc gggcggtgcg gttttaacgg cggttttatg tattatcgcc gggttgtggg
     2401 gctatccgat ggacttggcg atttggcagc cggtattgag cgtagccttg gtcgtaggcg
     2461 tatacttacc gcttttggaa gcgggcatgg aaatgacgcg caaaggcaaa accacccaat
     2521 ccgccgccat cgtggtgttc tcttccgcct tggtcaatcc ggttttcggc tgggcgttga
     2581 cgatgctgtt ggataatttg ggcttaatcg gctgcaaaga gcgcagtgcg caattaggtt
     2641 tcgccggacg cgtgttgata cccgcagtag gtttcttgat cttgtgtgtg gcgatgggtg
     2701 cggtcgggat gctgcccggt atcccgccgt ttttggaaca cttcaaatct ttgggctagg
     2761 ctgaaatcgg aaatgccgtc tgaaccgctt tcagacggca tttttgcaaa caggcaaaat
     2821 gacggcggcg ggatttttta ttttcccgat tgaagtataa tgttgccggg cttcaactgg
     2881 atattcaaac ggtctgctcc aacactcgga acggcgcata aaacgccacc tgcgcgttat
     2941 cccgaacggg gcggctaatc agatcctatc gccataaaac ggcggggttt caaccgaaaa
     3001 ggaattgaga tgaataaaac cttgtctatt ttgccggtgg caatcttact cggcggctgc
     3061 gccgccgggg gcggtaacac attcggcagc ttagacggtg gcacaggcat gggcggcagc
     3121 atcgtcaaaa tggcggtcgg gagccaatgc cgtgcggaat tggacaaacg cagcgaatgg
     3181 cgtttgaccg cgctggcgat gagtgccgaa aaacaggcgg agtgggaaaa caagatttgc
     3241 gcttgcgtcg cccaagaagc acccgaacgg atgaccggca acgatgtgat gcagatgctg
     3301 gctccgtcca cgcgcaatca ggcacttgcc gccctgaccg ccaaaacggt ttccgcctgc
     3361 ttcaaacacc tgtaccgcta accttcttca gacggcatga ggcagatgcc gtctgaagcc
     3421 gttttcctgc aatttcgaca gacgagaaaa atcatgaaat acatcagcac gcgcggcgaa
     3481 accgcacaca aaccgttcag cgaagtttta ttgatggggc ttgcccccga cggcggcctg
     3541 atgctgccgg aacattatcc gcaaatcggg cgcgaaacct tggacaaatg gcgcggttta
     3601 gcttatcccg aattggcgtt tgaaattatg cgcctgtttg ttacggatat tccggaggac
     3661 gatttgcgcg acattctgaa ccgtacttac acggaagcgg cgttcggtac taaggaaatc
     3721 acccccgtcc gcacgctttc agacggcatc aaaatccaag ccttgtccaa cggcccgacg
     3781 ctggcgttca aagatatggc aatgcagttt ttgggcaatg cgtttgaata tgttttaaac
     3841 aaagaaggca aaaaactcaa tatcttgggc gcaaccagcg gcgatacggg ttcggctgcg
     3901 gaatatgcct tgcgcggcaa aaaaggtgtg aatgtattta tgctgtcgcc cgatggcaaa
     3961 atgagcgcgt tccaacgcgc gcaaatgtac agcctgcaag acgggaatat ccacaatatc
     4021 gccgtgaagg gaatgtttga cgactgtcag gatattgtga aggcggtgca gaacgatgcc
     4081 gcgttcaagg aaaaatacca tatcggtacg gtcaattcga tcaactgggg acgcatcgtc
     4141 gcgcaagtgg tttattactt tgccggctat ttcaaagcga cgcaaagcaa tgacgagcaa
     4201 gtcagctttt gcgtgccgag cggcaacttc ggcaacgttt gcgcgggaca catcgccaaa
     4261 cagatgggtt tgcctatccg ccgcctgatt gtcgcgacca atgaaaacga tgtgttggac
     4321 gagtttttca aaaccggtgc ataccgcccg cgcaacagcg cgcatactta tgttacctcc
     4381 agcccgtcga tggacatttc caaagcgtcc aacttcgagc gtttcgtgtt cgacctgatg
     4441 gatcgcgatc ctcaggaaat caatacgctg tgggcggaag tagcggcggg caaaggcttt
     4501 gacctgcggt ttgctttaga aaaagtcggt ggcaaatacg gttttacctc cggcaaatcc
     4561 acccaccccg accgcctcgc caccatcaga caggtttatg agcaagacca agaactcatc
     4621 gacccgcaca ctgccgacgg cgtaaaagtc gcccgcgaag tgcgcgaaga aggggaaacg
     4681 gtggtttgtt tggaaaccgc gttggcagcg aaattcgatg cgaccatacg cgaagccgtc
     4741 ggcgatgccg ccattccgcg ccctgccgcg ctggaaggtt tggaaaacct gccgcagcgc
     4801 gtgcaaaccg tgccgaacag tgcggatgcg gtaaaaggca tcatcgaaca aacccttgcc
     4861 tgatgttccg tacaggggca ctccgtccga acttaagatt gaaagaaaat gaccttacct
     4921 atgcaggaaa cccgtttttc catactgcta gacgaattgg cggcaaaaca gaaggcagcc
     4981 atcgcccccc acctgcttgc cgacgggagc aaggtatgga tacgcaaagc aggcaggcac
     5041 aatgcgcgat ggcgttacgc gctgctcggt atggttgccc gatatttgaa actgggggtg
     5101 ttgaagccgg ttcccagcct cggcggcgag cctgccattg caaccgaatc aaaacgcctg
     5161 tacgaattgc gcgcggcggg gatagccgtt cccgaattgc tcgccgtcag gaaaaatgcc
     5221 cttatgttcg gaaatttgga aggtatcccg ctcgatacgc aaatccgcca agaagccgaa
     5281 gccggaaagg cggacgcttg gcttgccggt ttggaagcca ttgcacgcgt gcataaaaaa
     5341 cagcagttcc tcagtcaggc gtttgcacga aatatgatgt cggacggaaa aaacatcagc
     5401 tttttggatt ttgaagacga cccttccgag gtcctgacca tagcgcaatg ccaagcccgc
     5461 gattggctct gctacattca ttcgaccgcg ctgatattga aaaacggcgg actgctggaa
     5521 gcggctgcgg aaaaatgggg cggcgtattg tcggatcagc ctgccgaaat acaaaagctg
     5581 attgccgcca ccgtcaaacc gatcctcccg atccgcaggc tggaacaccc acgctgggga
     5641 cgggacgcac tcaggctggc agcctcgatt tccctgattt cccttgccga tatgccgcca
     5701 taagccgccg cccgccccgc gatgccgtct gaagcccttc agacggcata taaccaacgc
     5761 gcatcaagca ttgtcgcaac catccgtttc gtttagaatt ttggctttat cccgaatcgg
     5821 gcagacattt ccactctgcc gcacctcccg aacaagcact atccatttct tttactgaca
     5881 ggaaacccaa atggcagcat tcaataccca aaaagtattg tccgtacacc actggacaga
     5941 cgcatatttt acctttacct gcacccgcga cgaatcgttg cgctttgaaa acggacagtt
     6001 cgttatggtc ggattgatgg tggacggcaa gccgctgatg cgcgcataca gcgtcgcctc
     6061 cgccaactgg gaagaacacc tcgaattttt cagcattaaa gtccaagacg gtccgctgac
     6121 cagccgcctg caacacctca aagtcggcga cgacgtgtta atcagcaaaa aaccgaccgg
     6181 aactctggtt gccggcgacc tgaatccggg caaacacctt tacttgttga gcaccggtac
     6241 cggcatcgcc cctttcttga gcatcaccaa agaccccgag atttacgagc aatttgaaaa
     6301 aatcatcctc gtacacggcg tgcgctacaa aaaagatttg gcgtactacg accgctttac
     6361 caaagaattg cccgaacacg aatacctcgg cgacttggtt aaagaaaaac tgatttacta
     6421 cccaattgtt tcccgagaag aattcgaaca ccacggccgc ctaaccgacc tgatggtgag
     6481 cggcaaactg tttgaagaca tcggcctgcc caaaatcaac ccgcaagacg accgcgcgat
     6541 gctgtgcggc agccccgcga tgctgaaaga cacctgcaaa gttttggacg atttcggact
     6601 aaccgtttct ccgaaaacag gcgtgcgcgg cgattacctg attgagcgcg cgtttgtgga
     6661 tcaataagct gcttgaaaat gccgtctgaa cggcatcagc gataaaaaaa cccgaatcct
     6721 gccaatcagg attcggggtt tttatagtgg gtaaaaatta gaaatgcaca tttccgtcat
     6781 tccaacacag gtgggaatcc ggacttacct gtttcattat cgtttgaaaa taaaagagaa
     6841 accaaacata tagattcccg cttgcgcggg aatgacgacg gtgttttgcc gtagccaaag
     6901 cagaaaaaca tccctattgt catttcatca tgatatgaca ataggatgtt aaaaattaat
     6961 tatcattata tgattgatat ataagaaaaa ctgtcccaat aagaaatgtt atgcagaaaa
     7021 taaaatgaaa aggatggttt tcattgaaaa tggttgttct gccaccgtca tacacagaac
     7081 cggtatttgg aaaaaaaata atccatattg acatcattat tccatttatc gcataaatcc
     7141 actttttaat tttttttcct cattaatata atctcttatt taataaaatc aaatacctag
     7201 caattcgatc tcaaatttta aacgccaacg tgtttgagcg gtaacaatgc atactttaag
     7261 tttgtaatcc ttcatcgtct catttttgtt ttaatcgact atacgtctaa agcaacgccg
     7321 tccgtcattg ttcggacggc attttttcag acggcatttt cccccgtttg tgaaggcgca
     7381 aggcattgcc caaaaccgcc agcgaactga aactcatacc cagtgcggct atccacggtt
     7441 ggacatagcc caaaacggca agcggtacgg caatgatatt gtacgcgccc gcccatatca
     7501 ggttttgccg gataatctgc cgggtgcgcc gcgcctgatc gagcaggtgg gcgacggtac
     7561 gcaaatcttc gttcaataac acaatgtccg cgccgtccct cgcaatatcc gtcccgcccg
     7621 ctgcggcggc ggatacgtct gcctgcgcca aaacgggcgc gtcgttgatg ccgtcgccta
     7681 tcatcagtac ttttttccct tctttttgca aggctttgac gtattccagt ttgtcctcgg
     7741 gcatggcttg ggcgcggtag tgcgtgatac ccagggcgcg ggcggtttcg gcaacggcgg
     7801 tttcgcggtc gccgctgagg atgtgcaggg tcaggttttt gcctgccaac tgccgcaccg
     7861 cctccgccgc gctgtctttc aaggggtcgg tcaggtagaa cacggcttgg aaaccgcttt
     7921 gactgccgag gtaaaccgcg ctgccgccgc cttctgtttg cggttcttta cctgaaattt
     7981 cggcgacata ggatgccctg cccaatgccc aaacctgtgt ttcgccgttg acggtcagtt
     8041 gcgcgcccac gccttcgccg atgcggttga ggcgttgttt aatagcgatg tcggggacgc
     8101 tgccgtctga aatgcggcag ttgaggatgg cgcgggcaag gggatgttcg gactgttgtt
     8161 ctaaagcctg cgccaccgcg agaacaaagg cttcgtctgt gcctctcaac aatgagatac
     8221 ggcggacggc gggtttgcct tgggtcagcg tgccggtttt gtcgaagatg atgtcggtgg
     8281 tttgggcgag ggtttcgatt gcctgctttc cgccgattaa aataccttcg cgcgccagcg
     8341 taccggtaga agctgccagc gcggtcggcg tggcaagcga taaggcgcag gggcaggtaa
     8401 tgaccagcag ggcgacggta atccacaatg cggtgtgcgc gtcggcgtac agcgtccagc
     8461 cgatgaagac ggggacggca agcaggagtt cgccgaatat gaaagacgag gcgtattgtt
     8521 ccgccaactc ggcagtgcgc ggtttttgcg ctaaggcgcg gtcgagcagg cggacgatgt
     8581 gcgacagtcg cgtgccgccg ccggtgcggt cggtgcgtat aatcaggggg ctttgcgtgt
     8641 tgagtgtgcc ggcggttact ttttcagacg gcattttggc gacgggcagg ctctcgccgg
     8701 tcagcataga ttcgttgacg gcactgcttc cttccagcac cgtgccgtca acggggatgg
     8761 tttcgcccgg tttgaccagc acgatatcgc ccgccttcaa tttgacgaca gctgcctcgc
     8821 aggtttcctg cgtatcgggg taatcgggca tatgatggca aaacgcagga atcagcttca
     8881 ccagcctctc ggcggcatcg cctgccttac ggcgggcaat gtgttccata aagcgtccgc
     8941 ccagcaggaa aaacagcagc atcgcgatgg attcgaaata catcccctgc cccgcatttg
     9001 tcgcaaggct gtaaacgccg gcgataaagg tcatgatgat ggcgacggta atcggcgtat
     9061 ccatgccgac gcggcggttt ttcaagtcgc gcagcgcgcc ttgataaaac gggacggcgc
     9121 aatagaatac gacgggcagc accattaaaa agccgcccca atggaggatt tgcaggaaat
     9181 cgggttcgat gtcgccgccg taaaggtagg tcggcagcgc gaacatcatc gtctgcatca
     9241 tccccagccc ggcaacggcg aggcggacga tgtattgttt gcgttctttt tggttggcgg
     9301 cttcgatttt ttgcgcgtca tagggtgcgg cggtgtagcc tatctgcctg attttcaaca
     9361 gaatgtcgga aaggcggatt ttgccgtcgt cccagacgac gcggcagcgg tgcgtgctgt
     9421 aattgaggtc gatgcggacg atgccgtctg tacgcaaaag ctgctgttcg atcagccaga
     9481 cgcaggcggc gcaggtgatg ccgccgagca ttaaaaccgc ctcgcgcgtg ccgccgtggg
     9541 tttccacaaa gtcggactgg acttcgggca ggtcgtacag gcggatttgg tcgaggattt
     9601 cttggggcgg cagctcggtt ttttgcgcgt cggcggtgcg ttgtttgtaa taactgccca
     9661 agcccgcgtc aataatgctt tgtgcgactg cctgacaacc ggcgcagcag gtttcgcggt
     9721 cttcgttttc gtaacggacg gtcagatgca ggttttcggg aacgtccagc ccgcagtgga
     9781 aacaggtttt tttcatggca tttcggtttc gtctgtgttt ggtgcggcgg cacaatactc
     9841 ggcaatggct tcgcgcagtg cgtctatacc ggtattttca gcaacggaaa tgcggacggc
     9901 ggcaattttt cccgcagcgt cgcgccatat gcccgtgttt tgttcttcag acggcagcag
     9961 gtcggttttg ttgtacacct tgatgcacgg aatatcgccg gcatggattt cttgcagtac
    10021 gttttccacg tcttcaatct gctgtccgct gttcggagcg gcggcatcga cgacgtgcag
    10081 cagcacatcg gcttgcgcgg tttcttccag cgtggcggaa aaggcggaaa tcagtttgtg
    10141 cggcagatcg ctgacgaatc cgacggtatc ggtcaggata atgctgcatt cgggactgat
    10201 gtacagccgc cgcgccgtcg tgtcgagtgt ggcgaaaagc tggtctttcg catatatgcc
    10261 cgacttggtc agccggttga acagactgga tttgccgaca ttggtatagc cgaccagcgc
    10321 aaacgttttg attgtgcccg attcgcggga cttgcggcgc agggcgcgct gttttttgag
    10381 gttggcaagc tgttttttca aggcattgat ccgatgggcg atcaatcggc ggtcggtttc
    10441 cagtttggtt tcgccggggc ctttcatgcc gataccgccg cgctggctct gcagatggcc
    10501 gtaaccgcgt atcaagcgtc ccgccaaatg gctcaattgt gccaactcga cttgcagcct
    10561 gccttcctgc gtgcgggcgc ggcgggcgaa aatcgccaga atcagcccca ctctgtccaa
    10621 tacgcggcat tggaggattt tttccaaatt gcgttcctgc gtgggcgtaa gttcgtggtt
    10681 gaatacgacc aaatcgatgc cgtctgcggc aactgcttcc gacagctccg ccgccttgcc
    10741 cgtgccgaca aacagcgcgg tgtgcggacg gtcgcgtttg gcagtctcca cgcgcacgga
    10801 atcgccgccc gccgctttga ccagctcgac agcttccgcc aatgccgtct gaaaaccgtt
    10861 cagacgggtg gcactgctgc ccgtaccatc tttgtccaac attacgccca ccagcatgac
    10921 gcgttcgggt tgcgcttggg tactgccgtt gcggcctgtt ctgcctgtca tgtattcaat
    10981 cctgtaaata aagggttacg cctcgttccg tttctccttc cggtgcaagc gtgatgcggc
    11041 tgcccgccat tccgtcaacg ctgaagacga tgccgcccgc cttgtgcctt cctatggaca
    11101 ggcggctgcc gggtcgctgc cggtaggtat aacgggtaca cgcttccaaa caccagcgtc
    11161 cgcgccagtg gatgaaatat ttttcgcctt ttctaaccgc aagtgtctcg ccgccgttta
    11221 cctcaaaata agggtaatcg ggttttcggg ttctaaactg ccatttcgcc tgcgcgcgcc
    11281 gtccgttgcg gacatagtcg aataccgccg tataaagcgt accgtattcc aaaggcttga
    11341 gcgggaaaag cgcgaattgg tacgcggtca gcctgccgtt ggggtcgttg ccggcggtta
    11401 aaaccctgac ggggcggatt tcgtttttac cctgatacag cttgaaactt ttcatcgtaa
    11461 ttttgcctgc cgcctcggaa aaatcaatgc tggcaggatt gcccgtgatt tcatattccg
    11521 gcacggggtc tggacgctcg ccgtggaaat aaggcagtgc gccgttgccg acgggatagg
    11581 ctgtatagag cagctcctgt gcgggcatgg cttcgtcggt gtacacgacc gcaccgttat
    11641 ggcaggcgtt gcggtaatat ttccgtcctg cttccggctg atttctgcct tgggcgcaat
    11701 gccgctcaaa cctgccgttg ccctgattga atacgagaac ggttttaccg ttttcgcgca
    11761 caaatgccgc tcctgcctca tccgtatggc ggtcaagtag ggaaaggcgg tggtagattg
    11821 cgctcattaa tccgtccact tggcgttgct gcgtgcggat gtcgctgtcg gacgattcgg
    11881 cggcttcctc ttccgtgctg atgttttcat gcacgccgtt gtagagatac ccggcaaggc
    11941 gtgtgcgttc ggtcagcttt tgtgcggtgt agtgcggatt gtcgggatgg tgttcgccgt
    12001 gtccgtcttc gggattgagc gtgagatagc gtgcgtgcct gcgggcggaa ttttccaaaa
    12061 ccggcgcgtg tgccagcttg tgcaaaccga tttgggcgcg gatgcggttg aggtagtgca
    12121 gcgcatcgcc gccgtccctg atttgcggtg cggacggata gacaagttcg cccgcgggca
    12181 gggattggtt ttgggtatga tagaaaacgc ctgccgccga acccaacagg agcagccgaa
    12241 taaaaaggga tttcataatg ccgtcctccc gacgcggcaa cggggtgttt tatcaaaacg
    12301 gcaaacttgc caatgcggtt tccgattgca gattgccaaa ccgacaaacc tttccccgtg
    12361 ccgatgccga acccgatgcc gtctgaacct tcagacggca tcgggtgttt atttgtccac
    12421 tcggatgggt gcaggttcgt attgtgtcga ttcgtccccg taatacagca cgccgagttt
    12481 gatggggatt ctgccctgcg atttgcggtg ggcgttggaa tcacgcaagg aataggcgca
    12541 gccgcaatat tcctgctggt agaagttttc gcgtttgcta atttcaatca tacgcgcgct
    12601 gccgccgcct ttgcgccagt tgaaatccca atacaccaca tcatcgtaag gcgcggcggc
    12661 gcggcggccg cagtcgttaa tctggttcat gtttttccaa cgggaaatgc ccagcgaact
    12721 ggtaaagacg gggaacccgt gttcatgcgc gtattgcgcg gctttttcaa aacgcatatc
    12781 gaaacacatc gtacagcgga tgccgcgttc cggctcaaac tccatgcctt tggctttggc
    12841 aaaccattct ttgcggtcgt tttcgtagtc gtcgtcttta tcgatgaagg ggatgccgaa
    12901 cttttccgca aagcgcacgt tttcctcttt tcggagcata tactctttgt gcggatggat
    12961 attgggattg taaaaataaa tggtgtagtc gatgccggag gccagcatgg cttccatcac
    13021 ttcgccgctg cacggggcgc aacaggaatg cagcaagact tttttatgtc cgccgggcgg
    13081 gacgagtatg gggcggtcaa tgtcggtaac ggtaggtttg ttttgtgttt ccattaactt
    13141 aacaatatct gtcgaatacg gttgaagcgg ctattttatc agagccgccg catgtaaaac
    13201 agggtgtcag ggcatcagcc cgagctgtct gaacgaacgg acggtttgcg ccgttacgat
    13261 aaaatggtcg agcagcgaca catcgaccag cgacattgcc tgtgccagcc gccttgtgaa
    13321 catgatgtct tcctgcgaag gttcgggcga gccgcccgga tggttgtgcg cgataatcag
    13381 gctgtcggca tattcgtcca atgccagttt gacgatttcg cggatgtaaa tcgtgttttc
    13441 cgcaaccgta ccgcgcgaca gctctctgac cgcaatcagt tggttttggc ggttcagcag
    13501 cagcgcgacg ctgacttcga ctttttcctg ccccaaatga aagcgtaaat aatcggcaac
    13561 ggtatcggga tcggacagga cgatgctctc ctgcaattct tccgccaata tccgccgccc
    13621 gatttccctg actacggcaa actgtgtgaa acttgccgtc cccatccctt tgtatgccga
    13681 cagtttgccg acctccgcgc tcatcagcct ccccaaactg ccgaactcct gcagcaaata
    13741 acgcgccaaa tcaaccgcac tcattccgcg cgtgccgacg cgcagcagga ttgccaaaag
    13801 ttcggcatca ctcaaagccg ccgccccgcg ttccaacagc ttttccctgg gcctttcccc
    13861 ctccggccat tgcttgatgc tcatgttttc ccttttttaa atagtctgag atgccgtctg
    13921 gaacaaatgt tcccacacgc caaatatccg aaatgccgtc tgaaccggat ttccgcttca
    13981 gacggcatct gtatttcaaa acagtcttac gccgtttctt ccaactcgat ggacgccgcc
    14041 agaagcgaca ggcgtgccat tacgccgtaa acgtagaggc ggttgtgttc gttgtccacg
    14101 tcgcagtctt tttcagagcg cggcataccc agcgagtccc attgttcgaa tacgcgcttg
    14161 caggcttcgg gcgcttcttg ggagttgtcg ccgttgccgg tggggatgct gttggacagc
    14221 ggcacaaaca ccataccgcc ggcgttgagg ttttcgtccg caccgcgccc ttcgtgtacg
    14281 cggaaaaagc cgccgatgac gaagcggtcc atcatataca cgacgggttc gcacaccgcg
    14341 ccgtttaagg tttcataagt ataaatccct tcttggacaa tcacttcgct gacttccaag
    14401 ccttctttga ctttcgccat tttattgcgg tttttacggt tcaatccgcg cacttcgtcg
    14461 gcggatttga cgctcatcac gcccatgccg taagtgccgg catcggcttt gacgatgacg
    14521 aaaggtttgt cggtaatgcc cgattcgtcg tatttggctt gaattttcgc cagcacacgt
    14581 tctaccgctt ccgccaacgc gtcttcgcct tcacgccctt ggaagtccaa accgccgatt
    14641 ttttcaaaat aagggttaat ttgccattcg tcgatgccga ttaacttggc aaattcggcg
    14701 gtaacttggt tgtacgcgcc gaaatgattt gttttgcggc gcgtcgtcca accgccgtgc
    14761 aacggcggca aaacggtttg gctgatgcct ttgaggatgt cgggaatgcc ggcggacaaa
    14821 tcgttgttca acaaaaccac gcaaggcgaa aagccgtctg caagatggac gcggtcgcgg
    14881 gtacgcaata aaggttccaa caggattttg tcgcccaatg cggtttcaaa ttcggtcggt
    14941 tcggttactt ccggattcag gctgcccaag cgcacttcat accctgccga acacaaaatc
    15001 tcgccgaggg cgtaaacgtt ttgcaggtaa aacgtattgc gcgtgtggtt ttcgggaata
    15061 atcaatacgg atttcgccgt ttcgcaggcg cgttgcaccg catcttgcgc ggcaaccgcc
    15121 gccagcggga taaagttggg attcagatta ttgaagccgc cggggaacaa attcatatcg
    15181 atagacgaaa ttttgtaacc ggcattgcgt atatcgaccg aaccgtaaaa cggcgggcgg
    15241 tgcgcgttcc actgcgtgcg gaaccacgcc tcgattttgg cgtgattgga caggattttt
    15301 gcctcaaacg cctgaagttg cgccgaatgt tcgggcgaca tcaccggtaa tttcatcttt
    15361 cgtctgcctc tgtgtgtttt ttgacaagat gcagatgata atgcctttga aagaatgacg
    15421 acaagtattc tttcgtatcg aatcatgctt tagatataac tgtttactga aatggacaat
    15481 acgtctaatt ttttcgttaa aattgtttgc aaaataacac cggctcaaaa attagacaaa
    15541 atttgttgcg cggtataaag aatacgtcta aaatccgccc aatccgcatt accatttatc
    15601 caaaagaaca acatcatgac agcacaaacc ctctacgaca aactttggaa cagccacgtc
    15661 gtccgcgaag aagaagacgg caccgtcctg ctctacatcg accgccattt ggtgcacgaa
    15721 gttaccagcc ctcaggcatt tgaaggcttg aaaatggcgg ggcgcaagct gtggcgcatc
    15781 gacagcgtcg tctccaccgc cgaccacaac accccgaccg gcgattggga caaaggcatc
    15841 caagacccga tttccaagct gcaagtcgat actttggaca aaaacattaa agagtttggc
    15901 gcactcgcct attttccgtt tatggacaaa ggtcagggca tcgtacacgt tatgggcccc
    15961 gaacaaggcg cgaccctgcc cggtatgacc gtcgtctgcg gcgactcgca cacttccacc
    16021 cacggcgcat tcggcgcact ggcgcacggc atcggcactt ccgaagtcga gcacacgatg
    16081 gcgacccagt gcattaccgc gaaaaaatcc aaatccatgc tgattgccgt tgacggcaaa
    16141 ttaaaagcgg gcgttaccgc caaagacgtg gcactttaca tcatcgggca aatcggcacg
    16201 gcgggcggta caggctacgc cgtcgagttt ggcggcgaag ccatccgcag cctttctatg
    16261 gaaggccgca tgactttatg caatatggcg atcgaagccg gtgcgcgctc aggcatggtt
    16321 gccgtcgacc aaaccaccat cgactatgta aaagataaac ccttcgcacc cgaaggcgaa
    16381 gcgtgggaca aagccgtcga gtactggcgc acgctggtgt ctgatgaagg tgcggtattc
    16441 gacaaagaat accgtttcaa cgccgaagac atcgaaccgc aagtcacttg gggtacctcg
    16501 cctgaaatgg ttttagacat cagcagcaaa gtgccgaatc ctgccgaaga aaccgatccg
    16561 gtcaaacgca gcggtatgga acgcgccctt gaatacatgg gcttggaagc cggtacgcca
    16621 ttaaacgaaa tccccgtcga catcgtattc atcggctctt gcaccaacag ccgcatcgaa
    16681 gacttgcgcg aagccgccgc catcgccaaa gaccgcaaaa aagccgccaa cgtacagcgc
    16741 gtgttaatcg tccccggctc cggtttggtt aaagaacaag ccgaaaaaga aggcttggac
    16801 aaaattttca tcgaagccgg ttttgaatgg cgcgaaccgg gctgttcgat gtgtctcgcc
    16861 atgaacgccg accgcctgac cccggggcaa cgctgcgcct ccacctccaa ccgcaatttt
    16921 gaaggccgtc aaggcaacgg cggacgtacc cacctcgtca gccccgctat ggcagccgcc
    16981 gccgccgtta ccggccgctt taccgacatc cgcatgatgg cgtaagtatt ttcaggcggt
    17041 ctttaagaat ttgacgcggc cgtctgaaat atgtcccgta aggcagaaac acctttaata
    17101 ttcaaaccaa ggagtttaac catgaacaaa cttttcatta ccgccctgtc cgccctcgcc
    17161 ttgtccgcct gcgccggcac ttgggagggc gcgaaacaag acaccgcccg caaccttgac
    17221 aaaacacagg ccgccgccga acgcgccgcc gaacaaacag gcaacgccgt cgaaaaaggc
    17281 tgggacaaaa ccaaagaagc cgtcaaaaaa ggcggcaatg ccgtcggacg cggcatttcc
    17341 catctcggcg gaaaaatcga aaacgccacc gaataaccga ttcgcgatgc cgtctgaaac
    17401 cgcttcagac ggcatcgtca gcacaagacg caaacccatg aaagccttta ccaaaattac
    17461 cgccatcgtc gccccgctcg accgcagcaa cgtcgatacc gacgccatca tccccaaaca
    17521 atttttaaaa tccatcaaac gcagcggctt cggccccaat gcctttgacg aatggcgtta
    17581 cctcgaccac ggcgaaccag gcatggacaa cagcaaacgc ccgttgaacc ctgatttctc
    17641 gctgaaccag ccgcgttacc aaggcgcgca aatcctgttg acgcgtaaaa acttcggttg
    17701 cggctcttca cgcgaacacg ccccttgggc attggacgac tacggcttcc gcgccgtcat
    17761 cgcccccagc ttcgccgaca tcttcttcaa caactgctac aaaaacggcc ttttacctat
    17821 cgtgttgacc gaagaacaag tcgatcggct tttcaaagaa gttgaagcca acgaaggcta
    17881 tcagctctcc atcgaccttg ccgaacaaac cctgaccacc cctggcggcg aaacattcac
    17941 attcgacatt accgaacacc gcaaacactg cctcttaaac ggcttggacg aaatcggact
    18001 gaccctgcaa catgccgatg aaattcacgc ctttgaagaa aaacgccgcc aaagccagcc
    18061 ttggctgttt aacggttaaa acctatgccg tctgaaggcc gttcagacgg catttctgat
    18121 aacatataat tgctgcaact gatgtaaaca gagggattat caattgcttt catctttcaa
    18181 gcgggcttag caacgctcta aattaatgca atacaactct atttcaaata aatttttaga
    18241 tttttaatat gcaacaaatt aaatttattg acttattttc cggaatgagt ggcatcagga
    18301 aaggattcga acaagcctgt cggaaacagt cggttgcttg cgaatgtgtt tttacttcag
    18361 aaatcaaacc ggcagctttg gaagtattga agcaaaacta ccctgatgaa gtgccgtatg
    18421 gagacataac gaaaattgaa acaggggata ttcccgattt tgacattctg ttggcaggct
    18481 tcccttgtca ggctttttct ttcgccggaa aaagattggg ctttgaagat acacggggaa
    18541 cgcttttctt tgatgtggca aggattttaa aagcaaaaaa accaaaaggt tttattttgg
    18601 aaaatgtgga aggattggtg acacacgata gaaaagattc gacacaaaaa tagggcgcac
    18661 cctgaccgtt attttggaaa ccttggaagc attgggctac tatgtttctt ggaaagtttt
    18721 aaatgcaaaa gatttcggca ttccccaaaa caggaagcgc atttatctga caggcagttt
    18781 gaaatccaaa cccgacttat ctttcgaaac aagcccaagt ccgaaattaa aaaatatttt
    18841 ggaatcggga ctgcctactg aaagcagccc tttcatcaag aaattgctaa aaaaatttcc
    18901 cccgtccgaa ctgtacggaa aatcagtaaa agacaaacgg ggagggaaaa acaatattca
    18961 cagttgggat attgaattaa aaggcgcagt aaccgaagaa gagaagcaat tgttaaatat
    19021 ccttctaaaa gaacggagga aaaaaaatgg gcttcagaaa tcggcataga ttggatggat
    19081 gggatgcctt tgacaaaagc gcaaatttca actttctata aacaccccga tctccaaaat
    19141 attttggaca gcctgacaga taaaggctat ttggttttag agcatccgaa acaaaaaatt
    19201 ggcgggcaaa gaatcaaaga tgaatccctg cccaaaggct acaatattgt ttcaggtaaa
    19261 aaatcttttg aaatcaataa aatattagat ccaaacgatg ttgcgccaac cttggttgca
    19321 atggatatgg agcacctttt cgtcgttgac aacggcggtt tgcgtacact taccggaaaa
    19381 gaagggttgc gcttattcgg ctatccggac gattattcgt ttgatattcc caaaaaagac
    19441 agatgcgatt tattgggtaa taccgttgcc gtccctgtga ttaaggcggt atctgaaaga
    19501 cttctgcata ctttataaac cgacagggat aaaatgataa aacttactgc acaacaaata
    19561 tttgataagt tgctggatga agaaaaaatc ttatcggcca atggtcaaat tagatttttc
    19621 ttgggcgatg tggatattat cgtcaaacaa aaagatgttg tcggcaacat cattcaggaa
    19681 tggctcggcg gatgattgag aaaaagggaa attgaatttg atgtttcaac caatacccaa
    19741 atgcctcccg atttcttttt aaataaaaaa gaccgcagca gagaattgtt ggaagtaaag
    19801 gcgttcaacc gaaataccgg cccgggtttt gatattgcag attttaaaat gtattctgat
    19861 gaaatcattc ataagcccta tatgctggat gtagactatt taatattcgg ttacgatatg
    19921 gacgacaacg gcaatgtaac catcaaggat ttatggctta aaaaagtatg gcaaattacg
    19981 agaagcatgg atgggtgggc aattaatctt caagtcaaaa aaggcgtggt gcataaaatc
    20041 cgcccgggtg tttggtacag cataaataaa aagaatatgc ctatgtttga atgcttggaa
    20101 gattttgttt ccgcaattga agaaaccgtt tatcaaaacc cggcaacacg gcataacgca
    20161 tccttatgga aaaagaaatt tgaggaagcc tataaaaaac actacaaccg atcgatttcc
    20221 atacctcgtt ggcacgaaat tgcacacaaa tacaaaaaga aataaccctt caaccatcaa
    20281 cccataagga aacttgaaat gaccaaacat atcgccatcc tccgaggtga cggcatcggt
    20341 cccgaaatcg tcgccgaaac cgtccgcgta ctcgacaaac tcatcgccca aggtttggat
    20401 gccggctacg aatacgcccc attgggcggc gaagcctatg acgaatacgg tcatccttat
    20461 cccgaattta cgcaaaacct ctgccgcaaa gccgatgccg tcctgcttgg tgcagtcggt
    20521 tctcctcaat acgacaacct cgaccgtccg ttgcgccctg agcgcggcct gttggcaatc
    20581 cgtaaggatt tgaacctgtt tgccaatttg cgtcctgctg ttttatatcc cgaattagcc
    20641 aacgcctcca cgctgaagcc tgaaatcgtt gctggtttga atattttgat tgtgcgcgaa
    20701 ctcaccggcg acatctattt cggcgaaccg cgcggcatcc gcgttctgga aaacggcgaa
    20761 cgcgaaggct acaacaccat gaaatacagc gaaagcgaaa tccgccgcat cgcccacgtc
    20821 gctttccaat ccgcccaaaa acgcagcaaa aaagtctgct ccgtaggcaa agccaacgtt
    20881 ttggaaacca ccgaactgtg gcgcgaaatc tttgaagaaa tcggcaaaca atatcccgat
    20941 gtcgaacttt cccatatgta tgtggacaac gccgctatgc agctcgtgcg cgcgcccaaa
    21001 cagtttgacg tgattgccac cggcaacatc ttcggcgaca tcctctccga cgaagcctcc
    21061 atgctgaccg gctccatcgg tatgctgcct tccgcttctt tggacgaaaa cggcaaaggc
    21121 ctgtacgaac cgtcccacgg ctccgctccc gacatcgccg gacaaaacaa agccaacccg
    21181 ctggccacca tcctctcgct cgcaatgttg ctgcgttaca gcctgaacga cgaagcgcgc
    21241 gcgcaacaag ttgaaaacgc cgtccaaaaa gtgctgcaac aaggcttgcg taccagcgac
    21301 atttacgaag aaggcacaaa actcgtttcc tgctccgaaa tgggcgatgc ggtactcgcc
    21361 gccttgtaaa aaaacaaagc gcggatcaca ccgcgctttt tcatctgccc ttttccgctc
    21421 gccccgttcg tcaaccgcct gcaaagccac cgtttaccgg caggaaatgc cataaatccc
    21481 cgcctatgtt aggataaacg cctttactgg ctcacacaaa ggattatcat catgaaaaaa
    21541 atcatcttcg ccgcactcgc agcggcagcc gttggcactg cctccgccgc cacctacaaa
    21601 gtggacgaat atcacgccaa cgcccgtttc gccatcgacc atttcaacac cagcaccaac
    21661 gtcggcggtt tttacggtct gaccggttcc gtcgagttcg accaagcaaa acgcgacggt
    21721 aaaatcgaca tcaccatccc cgttgccaac ctgcaaagcg gttcgcaaca ctttaccgac
    21781 cacctgaaat cagccgacat cttcgatgcc gcccaatatc cggacatccg ctttgtttcc
    21841 accaaattca acttcaacgg caaaaaactg gtttccgttg acggcaacct gaccatgcac
    21901 ggcaaaaccg cccccgtcaa actcaaagcc gaaaaattca actgctacca aagcccgatg
    21961 gagaaaaccg aagtttgcgg cggcgacttc agcaccacca tcgaccgcac caaatggggc
    22021 gtggactacc tcgttaacgt tggtatgacc aaaagcgtcc gcatcgacat ccaaatcgag
    22081 gcagccaaac aataaatctt gatgcgaatc agcacaaatg ccgtctgaac gtccttcaaa
    22141 cggcatttgt gccgtcttca tcaaaccgcc ccgccaaccg taagccgata tggcggagta
    22201 caacccgccg aaagatattt cagcggcagg cagggcttgc cggaaagtcc gga
//
LOCUS       DAXIDM010000025        22100 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000025 DAXIDM010000000
VERSION     DAXIDM010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 22100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22100
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.025"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(104..1888)
                     /gene="lpdA"
                     /locus_tag="ACFOAE_000780"
     CDS             complement(104..1888)
                     /gene="lpdA"
                     /locus_tag="ACFOAE_000780"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFC6884302.1"
                     /translation="MSLVELKVPDIGGHENVDIIAVEVNVGDTIAVDDTLITLETDKA
                     TMDVPAEVAGVVKEVKVKVGDKISEGGLIVVVEAEGAAAAPKAEAAAAPAQEAPKAAA
                     PAPQAAQFGGSADAEYDVVVLGGGPGGYSAAFAAADEGLKVAIVERYKTLGGVCLNVG
                     CIPSKALLHNAAVIDEVRHLAANGIKYPEPELDIDMLRAYKDGVVSRLTGGLAGMAKS
                     RKVDVIQGDGQFLDPHHLEVSLTAGDAYEQAATTGEKKIVAFKNCIIAAGSRVTKLPF
                     IPEDPRIIDSSGALALKEVPGKLLIIGGGIIGLEMGTVYSTLGSRLDVVEMMDGLMQG
                     ADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVA
                     AGRAPNGKLISAEKAGVAVTDRGFIEVDKQMRTNVPHIYAIGDIVGQPMLAHKAVHEG
                     HVAAENCAGHKAYFDARVIPGVAYTSPEVAWVGETELSAKASGRKITKANFPWAASGR
                     AIANGCDNGFTKLIFDAETGRIIGGGIVGPNGGDMIGEVCLAIEMGCDAADIGKTIHP
                     HPTLGESIGMAAEVALGTCTDLPPQKKK"
     gene            complement(1965..3554)
                     /gene="aceF"
                     /locus_tag="ACFOAE_000781"
     CDS             complement(1965..3554)
                     /gene="aceF"
                     /locus_tag="ACFOAE_000781"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004742 - dihydrolipoyllysine-residue
                     acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFC6884303.1"
                     /translation="MSIVEIKVPDIGGHENVDIIAVEVKVGDTIAVDDTLITLETDKA
                     TMDVPADAAGVVKEVKVKVGDKISEGGVILTVETGASAAEAAPAAAAETQPAPAAAPA
                     AAGGATVQVAVPDIGGHTDVDVIAVEIKVGDTVAEDDTLITLETDKATMDVPCTAAGV
                     VKAVFLKVGDKVSEGTAIIEVETAGSAAAAPAPAAQAAAPAPAAAPTPTAPAAAPAPA
                     AKIDEAAFAKAHAGPSARKLARELGVDLGQVKGTGLKGRIMGEDVKAFVKSVMQSGAG
                     KPAAASLGGGLDLLPWPKVDFSKFGSVEVKELSRIKKISGQNLSRNWVVIPHVTVHEE
                     ADMTELEEFRKQLNKEWEREGVKLSPLAFIIKASVSALKAFPEFNASLDGDNLVLKNY
                     FNIGFAADTPNGLVVPVIKDVDQKGLKQISQELTELSKKAREGKLKPQEMQGACFTIS
                     SLGGIGGTGFTPIVNAPEVAILGVCKSQIKPVWNGKEFAPRLMCPLSLSFDHRVIDGA
                     AGMRFTVFLAKLLKDFRRITL"
     gene            complement(3700..6363)
                     /gene="aceE"
                     /locus_tag="ACFOAE_000782"
     CDS             complement(3700..6363)
                     /gene="aceE"
                     /locus_tag="ACFOAE_000782"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004738 - pyruvate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HFC6884304.1"
                     /translation="MSTQLHDVDPIETQEWLDALSSVLEYEGGERAQYLLENLVKYCR
                     DKGVRMPHGTTTPYLNTVSVENEKGIPGDQNIEHRIRAFVRWNAAAIVLRAGKKDLEL
                     GGHIASFQSAATMYEVGFNHFWKAKGEGEEGDLVFFQGHVAPGIYARAFVEGRLTEDQ
                     LNNFRQEVDGHGLPSYPHPHLLPDFWQFPTVSMGLGPIMAIYQARFLKYLESRGLAKT
                     KGRKVWCFCGDGEMDEPESQGAIALAAREGLDNLIFVINCNLQRLDGPVRGNGKIIQE
                     LEGNFAGAGWNVVKVIWGRRWDRLLAKDKDGILRQRMEECLDGDYQTYKSKDGAYVRE
                     HFFNTPELKALVADMTDEQLWALNRGGHDPQKVYNAYDRAANHADGKPTVILAKTIKG
                     YGMGASGEGQNVAHQAKKMDKASLKQFRDRFDIPVTDEQIESGDLPYLTFAPDTEEYK
                     YLHARRDALGGYLPQRKPTQEVLEVPELSAFDAQLKSSGEREFSTTMAFVRILSTLLK
                     DKKIGKRVVPIVPDESRTFGMEGMFRQYGIWNPKGQQYTPQDKDQLMFYKESVDGQIL
                     QEGINEPGAMADWIAAATSYANSNFAMIPFYIYYSMFGFQRIGDLAWAAGDMHARGFL
                     LGGTAGRTTLNGEGLQHEDGHSHIQADLIPNCVSYDPTFQYEVAVIVQDGLRRMYANN
                     EDVFYYITLMNENYAHPDMPEGAEQDILKGMYLLKAGGKGDKKVQLMGSGTILQEVIA
                     GADLLKADFGVEADIWSCPSFNLLHRDAIEAERFNRLNPLETAKVPFVTSQLQGHDGP
                     VIAATDYIRSYADRIRAYIPNDYHVLGTDGFGRSDSRANLRSFFEVDRYNVAVAALSA
                     LANQGKVSKETVQQAIEKYGIKADSAPSWKR"
     gene            7058..8770
                     /locus_tag="ACFOAE_000783"
     CDS             7058..8770
                     /locus_tag="ACFOAE_000783"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFC6884305.1"
                     /translation="MKASQFFISTLKEAPAEAALASHKLMIRAGLIKANASGLYTWMP
                     MGLRVLRKVENIVREEMARAGSVELLMPVVQPAELWQESGRWEFYGKELLRLKDRHDR
                     DFCMGPTCEEVIADIVRKEINSYKQLPKNFYHIQTKFRDEVRPRFGVMRAREFVMKDA
                     YSFHADYASLQTTYDAMYDAYCRIFTRLGLAFRPVAADTGSIGGTGSHEFQVLAESGE
                     DVIAYSDTSDYAANIELAPTLPLKGERAAAQAVLTKVHTPNVKTIESLVEFLNIPVEQ
                     TLKSIVVEGENEGEIVLLLLRGDHEFNDIKAEKLAGVKSPLTMASPAAIVEQFGANGG
                     SLGPVGFAGKVYADFATEKGADWVIGANEDGYHYTGFNFGRDAAEPEFVDLRNVVEGD
                     ESPDGQGRLKLARGIEVGHVFQLRDKYTQAMNVSFLDNNGKSQIMEMGCYGIGITRVV
                     AAAIEQNNDEKGIIWTKAMAPFEVVIVPMNYKKSDTVREAADKIYAELLAAGADVLLD
                     DRDERAGVLLNDSELLGIPHRIVIGDRALKEGNVEYAERRNNEAQAVAIGEIVARVTA
                     SLNG"
     gene            8833..9489
                     /locus_tag="ACFOAE_000784"
     CDS             8833..9489
                     /locus_tag="ACFOAE_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HFC6884306.1"
                     /translation="MASVFLEGEAVEVGNIFCIGRNYAAHIEELKNEIPSEPVVFMKP
                     SGSILNSGGTILLPEFSRDVQFECELVLLVGKDSDGMGEGEDILGCVAGYGVGLDLTA
                     RDIQCHLKAQGLPWLKAKGFRHSACVSDFAAAGRISNPEKVLFSLKQNGVLKQRGDTG
                     LMIYPIREILHKLAADYGLGKGDLVFTGTPSGVGAIGAGDNLALELDGLVRASFTVGC
                     "
     gene            complement(9499..9954)
                     /gene="ruvX"
                     /locus_tag="ACFOAE_000785"
     CDS             complement(9499..9954)
                     /gene="ruvX"
                     /locus_tag="ACFOAE_000785"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFC6884307.1"
                     /translation="MHKIPKGTALAFDFGEARIGVAQGDAELGLSHPLSTVTGGSNDE
                     KFAAIAKLVQEWQPRYFVVGLPVHTDGTKHEMTHLSRKFGRRLNGRFNLPVYWVDERL
                     SSVYAESLLSEAQVFGKKRKSVLDQVAAQAILHGFFEGGPAECFNGREG"
     gene            complement(9947..10495)
                     /locus_tag="ACFOAE_000786"
     CDS             complement(9947..10495)
                     /locus_tag="ACFOAE_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HFC6884308.1"
                     /translation="MNLSNHFLVAMPDMEDAFFSQSVVYICKHDEDGALGIAINKPSP
                     ITMDMIFSATGKNIPMRMQHDSVMMGGPVQVERGYVVHTPIGNWQSSIGVSDNIALTS
                     SRDVIENISREGAVDKALISIGYSSWGKGQLERELADNAWLTVPADEHILFDIPYEHR
                     YAAAFAKLGIDPLALFSGAGHA"
     gene            complement(10497..11057)
                     /locus_tag="ACFOAE_000787"
     CDS             complement(10497..11057)
                     /locus_tag="ACFOAE_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CreA family protein"
                     /protein_id="HFC6884309.1"
                     /translation="MNRLLLLSAAVLLTACGSGETDKIGRASTVFNILGKNDRIEVEG
                     FDDPDVQGVACYISYAKKGGLKEMVNLEEDASDASVSCVQTASSISFDETAVRKPKEV
                     FKHGASFAFKSRQIVRYYDPKRKTFAYLVYSDKIIQGSPKNSLSAVSCFGGGIPQTDG
                     VQADTSGNLLAGACMISNPIENPDKR"
     gene            11385..13175
                     /locus_tag="ACFOAE_000788"
     CDS             11385..13175
                     /locus_tag="ACFOAE_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFC6884310.1"
                     /translation="MRYKPLLLALMLVFSTPAVAAHDAAHNRSAEVKKQTKNKKEQPE
                     AAEGKKEKGKNGAVKDKKTGGKEAAKEGKESKKTAKNRKEAEKEATSRQSARKGREGD
                     KKSKAEHKKAHGKPVSGSKEKNAKTQPENKQGKKEAKGQGNPRKGGKAEKDTVSANKK
                     VRSDKNGKAVKQDKKYREEKNAKTDSDELKAAVAAATNDVENKKALLKQSEGMLLHVS
                     NSLKQLQEERIRQERIRQARGNLASVNRKQREAWDKFQKLNTELNRLKTEVAATKAQI
                     SRFVSGNYKNSQPNAVALFLKNAEPGQKNRFLRYTRYVNASNREVVKDLEKQQKALAV
                     QEQKINNELARLKKIQANVQSLLKKQGVTDAAEQTESRRQNAKIAKDARKLLEQKGNE
                     QQLNKLLSNLEKKKAEHRIQDAEAKRKLAEARLAAAEKARKEAAQQKAEARRAEMSNL
                     TAEDRNIQAPSVMGIGSADGFSRMQGRLKKPVDGVPTGLFGQNRSGGDVWKGVFYSTA
                     PATVESIASGTVSYADELDGYGKVVVVDHGENYISIYAGLSEISVGKGYMVAAGSKIG
                     SSGSLPDGEEGLYLQIRYQGQVLNPSSWIR"
     gene            13302..14786
                     /locus_tag="ACFOAE_000789"
     CDS             13302..14786
                     /locus_tag="ACFOAE_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HFC6884311.1"
                     /translation="MSKPVFKKIALYTLGAISGVAVSLAVQGFAAEKDRRDNEVLPVQ
                     SIRTMAEVYGQIKANYYQDKPDADLFEGAMKGMVAGLDPHSEYMDKKGYAEIKESTSG
                     EFGGLGMEIGQEDGFVKVVSPIEDTPAERAGVKSGDFIVKIDNVSTRGMTVSEAVKKM
                     RGKPGTKITLTLSRKNADKPIVVNLTRAIIKVKSVRHHLIEPDYGYIRVSQFQERTVE
                     SVNTAAKELLKENKGKPLKGLVLDLRDDPGGLLTGAVGVSAAFLPSEAVVVSTKGREG
                     MEGFVLKARPEDYIFKAGADPLAGIPAELKTIPMTVLINSGSASASEIVAGALQDHKR
                     AVIVGTQSFGKGSVQTLIPLSNGSAVKLTTALYYTPNDRSIQAQGIVPDVEVKDKERI
                     FESREADLVGHIGNPLGGEDVNGETLAVPLEKDADKPAVKEKGKKKKDEDLSSRRIPN
                     PAKDDQLRKALDLVKSPEQWQKSLGLAAKKPVSNKDKKDKKDKK"
     gene            15043..17142
                     /gene="uvrB"
                     /locus_tag="ACFOAE_000790"
     CDS             15043..17142
                     /gene="uvrB"
                     /locus_tag="ACFOAE_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFC6884312.1"
                     /translation="MPSERRFRPIPTTHFVRKRITGKIMEVIQYPNSPFKLHQPFPPA
                     GDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQ
                     LYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNL
                     MTRNDVIIVATVSAIYGIGDPTEYKQMVLSVKEGDTLEQRDIISTLVSMQYERGEMDF
                     KRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLIQRVGRYTVFPS
                     SHYVTPRDTVLRACDSIKEELRDRIEFFANEQRPVEQQRIEQRTRFDLEMLYEMGFCK
                     GIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLV
                     DYGFRLPSARDNRPLKFHEFEKVMPQTVFVSATPAKYEEEHAGQVVEQVVRPTGLVDP
                     QIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKGRYLHSD
                     IDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQ
                     TIGRAARNVNGVAILYADKITDSMKAAIDETERRREKQIKFNEEHGIVPQQIKKQVKD
                     IIDGVYHEDDGGKGRRQGKNKVKVGEIHNEEDAIKEIAKLEKAMQQAAKDLQFEEAAV
                     LRDRIRGIKENLLFEAE"
     gene            17177..18154
                     /locus_tag="ACFOAE_000791"
     CDS             17177..18154
                     /locus_tag="ACFOAE_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884313.1"
                     /translation="MEKIYLDYQFIIDEVDDRKNWKLSNIDDNKYQIVYSPAHIEEIV
                     RGKKCNKLKGNIFLYTNYVSNLTKDRQLIRTDASTAKILEKPFGENGIFLVEENPRYC
                     CQRVLKYLDKNEIAEEGQKQILEDGNRKFEQFNQKNRQKKVVGIQKLSILDIFNRDDD
                     VFNEFLTKIVYSYILKNIVSENLNKFNLDNNLYMELLCKSFFSNININNRIEKERNRF
                     EKIFRDKDNIFKEISSEHHLVENIIDNLMKTLMSCGFYLEAERKATSNLHDTTHCIYA
                     AYSDFFITRDKKLKYRVEAIYKYLGVKTQVIFVDSSDNEDILVDRFGKP"
     gene            18523..18963
                     /locus_tag="ACFOAE_000792"
     CDS             18523..18963
                     /locus_tag="ACFOAE_000792"
                     /inference="COORDINATES: protein motif:HMM:NF020904.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC6884314.1"
                     /translation="MQAIREYTQNRLPESYYLFLQQCGTGDFFYSWYTSVIDQTVSQM
                     PKIEIYNLTQLKEENIYYQQLLREELDDIPPDEHPDIGKILIIGAHHSMGDWFGFDLS
                     RAEPNFDIFIHDAANHATYAEEAEWRRFEDWIIRCVESEGEDTL"
     gene            complement(19123..19470)
                     /locus_tag="ACFOAE_000793"
     CDS             complement(19123..19470)
                     /locus_tag="ACFOAE_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010357745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884315.1"
                     /translation="MTYLKIITISIVLYILLLQINLKMLEKRIDFLVENIDKYYQQYG
                     SYPNNFDFISTKTNFTTESYCDFWDKNIAGYGNCYFVKNDKDYTILVMGFSSKILFSS
                     HNKIKEFNSNKYD"
     gene            complement(19802..20518)
                     /gene="trmB"
                     /locus_tag="ACFOAE_000794"
     CDS             complement(19802..20518)
                     /gene="trmB"
                     /locus_tag="ACFOAE_000794"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFC6884316.1"
                     /translation="MTDTAENQTPNDRQAGHPRSIRSFVLRQSHMTAAQQRAIDTLWD
                     SFGIDYQATPADLDANFGSNRPKILEIGFGMGTATAEIARRLPETDFLAIDVHGPGVG
                     NLLKLIDENHLENIRVMRHDAVEVVENMLQDGSLDGIHIFFPDPWHKKRHHKRRLIQT
                     PFIAKLLPKLKTGGYIHLATDWEEYAQQMLEVLSSFDSLQNTAADYAPTPDYRPETKF
                     EVRGKRLGHGVWDLVFKRIR"
     gene            complement(20640..22048)
                     /locus_tag="ACFOAE_000795"
                     /pseudo
     CDS             complement(20640..22048)
                     /locus_tag="ACFOAE_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674669.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
BASE COUNT         5516 a         5299 c         5863 g         5422 t
ORIGIN      
        1 ccggagaaga tattttaatc cgctgtaaaa tagaaaatgc cgtctgaaca tttcagacgg
       61 catttgctca aataaacctt atcggctgtt tattcagtcg gatttatttt ttcttttgcg
      121 gaggcaggtc ggtacaagta cccaatgcca cttccgccgc cataccgatg gattcgccca
      181 aggtcgggtg cgggtggatg gttttgccga tgtctgccgc gtcgcagccc atttcgatgg
      241 caaggcagac ttcgccgatc atgtcgccac cgttcggacc gacaatgccg ccgccgatga
      301 tgcggccggt ttcggcatca aaaatcagct tggtaaagcc gttgtcgcaa ccgttggcaa
      361 tcgcacggcc ggaagccgcc cacgggaagt tggctttggt gattttgcgg ccggatgctt
      421 tggcggacaa ctcggtttcg cccacccacg ccacttcggg ggaagtgtag gcaacgcccg
      481 gaatcacgcg cgcgtcgaag taggctttgt ggccggcgca gttttcagca gcaacgtggc
      541 cttcgtgaac ggctttgtgt gccaacattg gttgaccgac gatgtcgccg atggcgtaga
      601 tgtgcggcac attggtacgc atttgtttgt ccacttcgat gaagccgcga tcggtaacgg
      661 caacgcctgc tttttccgcg ctgatgagtt tgccgttggg cgcgcggccg gcggcaacca
      721 atacggcatc gtaacgttgc ggctctttag gcgcatttgc accttcaaag gtaacgtaaa
      781 cgccgtcttc tttcggctcg actgcaacgg ttttggtgtt gaccataatg ttgtcaaaac
      841 ggtattcgtt ttgtttttgc catactttta ccaaatcgcg gtctgcgcct tgcatcaggc
      901 cgtccatcat ttcaaccaca tccaaacgcg aacccagcgt gctgtaaacc gtacccatct
      961 cgaggccgat aatgccgccg ccgataatca gcagtttgcc cggtacttct ttcagagcca
     1021 atgcgccgct ggaatcgatg atgcgcggat cttcaggaat gaaaggcagt ttggttacgc
     1081 ggctgcctgc tgcaatgata cagtttttga aggcaacgat ttttttctcg ccggtagtgg
     1141 ctgcctgttc gtacgcgtcg ccggcagtca gcgacacttc caagtggtgc ggatctaaga
     1201 attgcccgtc gccttggata acgtccactt tacggctttt cgccatacct gccaaaccgc
     1261 ccgtgaggcg ggaaactacg ccgtctttgt aggcgcgaag catatcgatg tcgagttccg
     1321 gctcggggta tttgataccg ttggcagcca agtggcgcac ttcgtcgata acggcggcat
     1381 tgtgcaacaa ggctttggaa gggatacagc cgacgttcag gcaaacgccg cccaaagttt
     1441 tgtaacgttc gacgatggcg actttcaagc cttcatcggc agcggcaaat gcagcggagt
     1501 aaccgccggg accgccaccc aatacgacca cgtcgtactc ggcatcggca gaaccgccga
     1561 attgcgcggc ttgcggtgca ggagcggcgg ctttgggtgc ttcttgtgcc ggggcggcag
     1621 ccgcttcggc tttaggagcg gcagccgcgc cttcggcttc aacgacgaca atcaaaccgc
     1681 cttcggagat tttgtcgccg actttgactt tcacttcttt gaccacgcca gcaacttcgg
     1741 caggtacgtc catcgtcgct ttgtcggttt ccaaggtaat cagggtgtcg tcaacggcga
     1801 tggtgtcgcc cacgtttact tcaaccgcga taatatctac attttcgtgt ccgccaatgt
     1861 cgggcacttt taattcaact aagctcatgt ctcatctttc tgaatgatgt tcaaacttcc
     1921 ttttcagacg gcacagaccg ctatgccgtc tgaagccgat cgggttacag ggtaatgcgg
     1981 cggaagtctt tcaacagctt cgccaagaat acggtgaagc gcataccggc cgcaccgtcg
     2041 atgacgcggt ggtcgaagga caggctcaac gggcacatca ggcgcggggc aaactctttg
     2101 ccgttccaaa ccggtttgat ttgggatttg cacacgccca agatagcaac ttcaggagca
     2161 ttcacaatcg gcgtgaagcc tgtaccgccg ataccgccca agctggaaat ggtaaagcac
     2221 gcgccttgca tttcttgcgg tttgagcttg ccttcgcggg cttttttaga caattcggtc
     2281 agctcttggc tgatttgttt caagcctttt tgatccacgt ctttgatgac gggaacaacc
     2341 aagccgttcg gcgtatcggc tgcgaaaccg atgttgaagt agtttttcag caccaggttg
     2401 tcgccgtcca aagaagcgtt gaattcgggg aaggctttca gcgcggaaac ggaggctttg
     2461 ataatgaacg ccaacgggga cagtttcacg ccttcgcgtt cccattcttt gttcaactgt
     2521 ttgcggaatt cttccaattc ggtcatgtcc gcttcttcgt gtacggtaac gtgaggaatc
     2581 acaacccagt tgcgagacag gttttgaccg gagattttct taatgcgtga cagttcttta
     2641 acttcgacgc tgccgaattt agagaagtca actttaggcc atggcaacaa gtccagaccg
     2701 ccacccaaag aagcagcggc aggtttgcct gcaccgcttt gcataacgga tttaacgaaa
     2761 gctttaacgt cttcgcccat gatacggcct ttcagaccag tacctttaac ttgacccaag
     2821 tccacgccca attcgcgtgc cagtttacgt gcagaaggac ctgcgtgcgc tttggcaaac
     2881 gcagcttcgt cgattttggc ggcaggtgca ggtgcggcgg ccggagcggt aggagttgga
     2941 gcggcagccg gtgcaggtgc ggcagcttga gcggcaggcg caggggctgc tgcggcagag
     3001 ccggcggttt ctacttcgat aatggcagta ccttcggaca ctttgtcgcc gacttttaag
     3061 aatacggctt taacgacacc ggcagcggta caaggtacgt ccattgtcgc tttatcggtt
     3121 tccaaagtaa tcagcgtgtc gtcttcggca acggtatcgc cgactttgat ctcgacggcg
     3181 attacatcta catcggtatg gccgccgatg tcgggaacgg ctacttgaac ggttgcaccg
     3241 cctgcggcag cgggtgcggc ggcaggtgca ggttgtgttt cagcggcagc agccggagcg
     3301 gcttcggcgg cggaggcacc ggtttcaacg gtcagaataa cgccgccttc agagatttta
     3361 tcgcccactt taactttaac ttctttcaca acgccggctg catcagcagg tacgtccata
     3421 gtagctttgt cggtttccaa agtaatcagg gtgtcgtcaa cggcaatagt gtcgcctact
     3481 ttgacttcta cggcgatgat gtcgacgttt tcatgaccgc cgatatcagg gactttgatt
     3541 tctacgatac tcatttgagt tcctttaata ttttcagttt gatgccgtct gaaaatttgt
     3601 ttcacacggc atcggtacag tttgttcaaa ccattcaagc attcggtttt cagacggcct
     3661 gatgtctgaa tgaagcaaac aggccgtctg aaacatcaat tagcgtttcc agctaggagc
     3721 tgaatcggct ttgataccat atttttcaat ggcttgttga acggtttctt tgctgacttt
     3781 gccttgattg gccaatgcgc tcaatgcagc aacggcaacg ttgtagcggt caacttcgaa
     3841 gaagctacgc aggttggcac ggctgtcgga gcggccgaag ccgtcagtac ccaagacgtg
     3901 gtagtcgtta gggatgtagg cacggatgcg gtcagcatag ctacggatat agtcggtagc
     3961 ggcaatcacc gggccgtcat gaccttgcag ttgagaagta acaaacggta cttttgcagt
     4021 ttccaaagga ttcaggcggt tgaaacgttc tgcttcgata gcatcgcgat gcaacaggtt
     4081 gaaagatggg caagaccaga tgtctgcttc tacgccgaag tcggctttca gcagatcggc
     4141 accggcaatc acttcttgca ggatggtacc agaacccatc agttggactt tcttgtcacc
     4201 tttgccgccg gctttcagca agtacatacc tttgaggatg tcttgttccg caccttccgg
     4261 catatccggg tgagcgtagt tctcgttcat cagggtgatg tagtagaaca cgtcttcatt
     4321 attggcatac atacggcgca gaccgtcttg tacgatgacg gcgacttcgt attggaaggt
     4381 cgggtcgtaa gaaacgcagt tcggaatcaa atctgcttga atatggctgt ggccgtcttc
     4441 gtgttgcaga ccttcgccgt tcagcgtcgt acggccggca gtaccgccca acaggaagcc
     4501 gcgtgcgtgc atatcgcctg ccgcccaagc caagtcgccg atacgttgga aaccgaacat
     4561 agagtagtag atgtagaaag gaatcatcgc aaagttgctg ttggcgtagc tggttgcagc
     4621 agcgatccag tcagccattg cgcccggttc gttaatacct tcttgcaaga tttgaccgtc
     4681 aacggattct ttatagaaca tcagttggtc tttgtcttga ggggtatatt gctgaccttt
     4741 cggattccaa ataccgtatt ggcggaacat accttccatg ccgaaagtac ggctttcgtc
     4801 gggaacgata ggtacgacgc gtttgccgat ttttttgtct ttcagcaaag tggacaggat
     4861 gcggacgaat gccatcgtgg tcgagaactc gcgttcaccg ctggatttga gttgtgcgtc
     4921 gaatgctgac agctcgggca cttccaatac ttcctgcgtc ggtttgcgtt gcggcaggta
     4981 gccgcccaaa gcatcgcggc gtgcgtgcag gtatttgtat tcttccgtat cgggggcaaa
     5041 agtcaggtaa ggcagatcgc cgctttcgat ttgttcgtcg gtaaccggaa tgtcaaagcg
     5101 gtcgcggaat tgtttcaggg acgctttgtc catttttttg gcttggtggg caacgttctg
     5161 accttcgccg gatgcgccca taccgtaacc tttaatggtt ttcgccaaga tgacggtagg
     5221 tttgccgtcg gcatggttcg ctgcgcggtc gtaggcgttg tacacttttt gcgggtcgtg
     5281 gccgccgcgg ttcaatgccc agagttgctc atcggtcata tcggcaacca atgctttcag
     5341 ttcgggcgta ttgaagaagt gttcgcgcac atacgcgccg tctttggatt tgtaagtttg
     5401 gtagtcgccg tccaaacatt cttccatacg ttggcgcagg ataccgtctt tgtctttcgc
     5461 caagaggcgg tcccagcggc ggccccaaat gactttgacg acattccagc cggcgccggc
     5521 aaagttgcct tccaattctt ggatgatttt gccgttgccg cgtaccggac cgtccaagcg
     5581 ttgcagattg cagttgatga cgaaaatcag gttgtccaag ccttcgcgtg cagccagtgc
     5641 gattgcacct tgagattcgg gttcgtccat ttcgccgtct ccgcagaaac accatacttt
     5701 acggcctttg gtttttgcca aaccacgcga ttccaagtat ttcaggaaac gcgcctgata
     5761 aatcgccatg atgggcccca agcccatgga tacggtcggg aactgccaaa agtcgggcaa
     5821 gaggtggggg tgcggatagg aaggcagacc gtgtccgtcc acttcttggc ggaagttgtt
     5881 cagctggtct tcggtcagac ggccctcgac gaatgcgcgt gcatagatgc ccggggcgac
     5941 gtgaccttgg aagaagacca aatcgccttc ttcgccttcg cctttggctt tccaaaagtg
     6001 gttgaaaccg acttcgtaca tggtggcggc agattggaaa gatgcgatgt gcccacccag
     6061 ttccaaatct ttcttgccgg cgcgcaatac gatggcggcg gcgttccagc gcacgaatgc
     6121 gcggatgcgg tgttcgatgt tttggtcgcc cggaatgcct ttttcgtttt caaccgaaac
     6181 ggtattcaaa tacggggtgg tcgtgccgtg tggcatacgt acgcccttgt cgcggcagta
     6241 tttgaccagg ttttccaaga ggtattgtgc gcgttcgccg ccttcatatt cgaggacgga
     6301 gcttaacgcg tccagccact cttgggtttc gatagggtca acatcgtgta attgggtgga
     6361 catagtatct atcctttatg ttgagtgttt aatcggcagg gagggtgtag ccaacccctt
     6421 tattttcgtt tgtgaaaaat aataagcaaa aacgaaaatt tctaaatcaa accgaaaaaa
     6481 aataatttaa gtttaatgtt ttcaaaaaat tataaaagtt ttggaaacaa gggaaaactt
     6541 gaaaaaaatg ttcgatctgc tccacacgaa atcctatcag caatcgggtc tgctggcaaa
     6601 taaccatgcc tgtaaaagca ggttttatac tgaagttggc gtttggtaag gtcaagtctt
     6661 tttgatttcg aaatattctg tttgattttg gcgatatttt ttcggaattg tggtatatcg
     6721 aatcattatg tctctgtcgg caattttcct attgtagaaa atctatacac aagctttgtg
     6781 gataaccgtg ttgataagcc acggcttgtg ttaaaaaagt cttacgcaac aaatgtacgc
     6841 ttattttgat taaaaaatag gcacatttaa atctataaaa atcatgtgct tatgttcaat
     6901 atgatgtttc tggtcatgtt tttgccgtct gttatgggat ttgtcccgcg cttggggcag
     6961 ggggtgaatt ttggaggttg gtgcaaaacc tgcttttttc gcgttacaat ctgcacccga
     7021 tttacttttg aatttgcctg tttggaaaaa tacttttatg aaagccagcc aattctttat
     7081 ctctacttta aaagaagccc ctgccgaagc cgcacttgcc agccacaagc tgatgattcg
     7141 tgccggtttg atcaaagcca acgcatccgg tctttatact tggatgccga tgggtctacg
     7201 cgtattgcgc aaagttgaaa atatcgtgcg cgaggaaatg gcgcgcgcgg gcagcgtgga
     7261 gttgctgatg ccggtggtgc agcctgccga gctgtggcag gaatccggcc gctgggagtt
     7321 ttacggtaaa gaactgctgc gcctgaaaga ccgccacgac cgcgatttct gcatgggccc
     7381 gacctgcgag gaagtcatcg ccgacatcgt gcgcaaagaa atcaacagct acaaacagct
     7441 gccgaaaaac ttttaccaca tccaaaccaa attccgcgac gaagtgcgcc cgcgtttcgg
     7501 cgtgatgcgc gcgcgcgagt tcgtcatgaa agacgcttat tccttccatg ccgactacgc
     7561 ctcgcttcag acgacctatg atgccatgta tgacgcttac tgccgcatct tcacccgtct
     7621 gggcttggca ttccgccccg tcgccgcaga caccggcagc atcggcggta cgggttcgca
     7681 cgagtttcaa gtgttggcgg aaagcggcga agatgttatt gcgtacagcg acacttccga
     7741 ttacgccgcc aatatcgagt tggcaccgac cttgccgctt aaaggcgaac gcgccgctgc
     7801 tcaggctgtg ttgaccaaag tgcatacacc aaacgtcaaa accattgagt ctttggttga
     7861 attcctgaat attccggttg aacaaaccct caaatccatc gtggtcgaag gcgaaaacga
     7921 aggcgaaatc gtcttattac tgttgcgcgg cgaccatgag ttcaacgaca tcaaggcaga
     7981 aaaactggcg ggcgtgaaat cgccattgac gatggcaagt cctgccgcga ttgtcgaaca
     8041 gttcggcgca aacggcggct cgctgggtcc ggtcggcttt gcaggtaaag tttatgccga
     8101 tttcgccact gaaaaaggcg cggactgggt catcggtgcg aacgaagacg gctaccacta
     8161 taccggcttc aacttcgggc gcgatgccgc cgagcctgaa ttcgtcgatt tgcgtaatgt
     8221 ggtcgaaggc gacgaaagcc ccgacgggca aggccgtctg aaactggcgc gcggcatcga
     8281 agtcggacac gtcttccagt tgcgcgacaa atacacccaa gccatgaacg taagcttcct
     8341 tgacaacaac ggcaaatcgc aaattatgga aatgggctgc tacggcatcg gcatcacccg
     8401 cgtcgttgcc gccgccatcg agcagaataa cgacgaaaaa ggcatcatct ggaccaaagc
     8461 aatggcgccg tttgaagtcg ttatcgtgcc gatgaactac aaaaaatcag acaccgtacg
     8521 cgaagccgcc gacaaaatct atgccgaatt gctggcggca ggcgcagacg tcctcctcga
     8581 cgaccgcgac gaacgcgcag gcgtattgct gaacgactcc gagcttctcg gtattccgca
     8641 ccgcatcgtc atcggcgacc gcgctttgaa agaaggcaat gtcgaatacg ccgaacgccg
     8701 caacaacgaa gcgcaggcag ttgcaatcgg agaaattgtt gcgcgtgtaa cagcttcatt
     8761 aaatgggtaa gcttggtcaa atgctgtctg aaaataattt cagacggcat ttttatttgg
     8821 ggagaaagtg aagtggcttc agtattttta gaaggagaag cagtcgaggt cggcaatatt
     8881 ttctgtatcg gcaggaacta tgccgcacat attgaagagt taaaaaacga aataccttcc
     8941 gaacctgtgg tgtttatgaa gccgtcaggc agcattttga acagcggcgg tacaatctta
     9001 ctgcccgagt tcagtaggga tgtgcagttt gagtgcgaac tcgtgctgct ggtcggtaag
     9061 gattcagacg gcatgggaga gggtgaagat attttgggat gtgtggcggg gtacggcgtg
     9121 ggtttggatt tgaccgcgcg agacatccaa tgccatctga aggcgcaggg gctgccctgg
     9181 ctgaaggcaa aagggttcag gcattccgcg tgcgtgtcgg attttgcggc ggcaggcaga
     9241 atcagcaatc ccgagaaggt gttgttttca ttaaaacaaa acggcgtatt gaaacagcgc
     9301 ggggataccg gtttgatgat ttacccgatt cgggaaattt tacacaaact ggcggcggat
     9361 tacggtttgg ggaaagggga tttggtgttt accggaacgc cctccggcgt gggcgcaatc
     9421 ggtgcggggg acaatttggc attggagctg gacggcttgg tgcgcgcctc tttcacggta
     9481 gggtgttaac cgcgccgctt aaccctcacg cccgttgaaa cattccgccg gaccgccctc
     9541 gaaaaaaccg tgcaagatgg cttgcgccgc cacttggtcg agcaccgatt tgcgtttttt
     9601 gccgaagacc tgtgcttccg aaagcaggct ttcggcatag acggacgaca gccgttcgtc
     9661 aacccaatag acggggagat tgaacctgcc gttcagcctg cgtccgaact tgcgcgacag
     9721 gtgcgtcatt tcatgtttcg tgccgtcggt atgcacgggc agtccgacga caaaataacg
     9781 cggctgccat tcttgaacca gcttggcgat tgccgcgaac ttttcatcgt tgctgccgcc
     9841 ggtaacggtg ctcaaaggat gggatagccc taattccgcg tctccttgtg ccacgccgat
     9901 acgcgcttcg ccgaagtcga atgccagtgc cgttcctttt ggaattttat gcatggccgg
     9961 ctcccgaaaa cagggcgagc gggtcgatgc cgagtttggc gaatgcggcg gcgtaacggt
    10021 gttcgtaggg gatgtcgaac aggatgtgtt cgtcggcggg aacagtcagc cacgcattgt
    10081 cggcaagttc gcgttcgagc tggccttttc cccagcttga atagcctatg ctgatcaagg
    10141 ctttgtcaac cgcaccttcg cgtgaaatat tttcaatcac gtctcgggaa gaagttagcg
    10201 cgatattgtc tgaaacgccg atactgcttt gccagttgcc gatcggggta tgcacgacat
    10261 aacctcgctc gacttgcacc ggcccgccca tcatcacgct gtcgtgctgc atccgcatgg
    10321 ggatgttttt gccggtggcg gaaaaaatca tgtccatcgt aatcggagag ggtttgttga
    10381 tggcgatgcc gagtgcgccg tcttcatcgt gtttgcagat atagacgacc gattgtgaaa
    10441 aaaacgcgtc ttccatatcg ggcatggcga cgagaaagtg gttggagagg ttcatatcag
    10501 cgtttgtcgg gattttctat cgggttggaa atcatgcagg cgccggcaag caggttgccg
    10561 gaagtatcgg cttgcacccc atcggtttgc ggtatgccgc cgccgaaaca ggaaaccgcg
    10621 cttaaggaat ttttcggcga gccttggatg attttatcgc tgtacaccaa ataggcgaag
    10681 gttttgcgtt tggggtcgta ataacggaca atctgccggc tcttgaacgc gaagctcgca
    10741 ccgtgtttga aaacttcttt cggtttgcgc acggcggttt cgtcaaaaga aatcgaagat
    10801 gccgtctgaa cgcacgaaac cgatgcgtcg gacgcgtcct cttccaaatt gaccatttcc
    10861 ttcaagccgc ctttttttgc atacgaaata taacaggcaa ccccttgaac gtcgggatcg
    10921 tcgaatcctt ccacttcgat acggtcgttt ttgcccagta tgttgaaaac ggtacttgcc
    10981 cgtccgattt tatcggtttc gccgctgccg caggcagtca gcaggacggc ggcagacagc
    11041 agtagcagtc tgttcatcaa aatttcctta tcggttgaat ccccgttttc cgtgaaggcg
    11101 gcagggcttg ctttgtttgg aggggcgcac gttcccaaaa tcgggcaaca tacggtatgc
    11161 ggcttaatgt gctaccctgt gtgtcggaac acaatatccg ttgcggcatt gaaaatatga
    11221 cgcacaatat aaggctgttt gagccgattg caagtatccg cgcaaagaag gcgcaagatt
    11281 gggcaaacgg cattttcaga cggcataact gacagtataa tccaaacgtc cggctgcttt
    11341 cgtgcagcct tcagtattat ccaacttttt ccgaaggtcg aaccatgcgc tacaaacccc
    11401 ttctgcttgc cctgatgctc gttttttcca cgcccgccgt tgccgcccac gacgcggcac
    11461 acaaccgttc cgccgaagtg aaaaaacaga cgaagaacaa aaaagaacag cccgaagcgg
    11521 cggaaggcaa aaaagaaaaa ggcaaaaatg gcgcagtgaa agataaaaaa acaggcggca
    11581 aagaggcggc aaaagagggc aaagagtcca aaaaaaccgc caaaaaccgc aaagaagcag
    11641 agaaggaggc gacatccagg cagtctgcgc gcaaaggacg cgaaggggat aagaaatcga
    11701 aggcggaaca caaaaaggca catggcaagc ccgtgtccgg atccaaagaa aaaaacgcaa
    11761 aaacacagcc tgaaaacaag caaggcaaaa aagaggcaaa aggacagggc aatccgcgca
    11821 agggcggcaa ggcggaaaaa gacactgttt ctgcaaataa aaaagtccgt tccgacaaga
    11881 acggcaaagc agtgaaacag gacaaaaaat acagggaaga gaaaaatgcc aaaaccgatt
    11941 ccgacgaatt gaaagccgcc gttgccgctg ccaccaatga tgtcgaaaac aaaaaagccc
    12001 tgctcaaaca aagcgaagga atgctgcttc atgtcagcaa ttccctcaaa cagcttcagg
    12061 aagagcgtat ccgccaagag cgtatccgtc aggcgcgcgg caaccttgct tccgtcaacc
    12121 gcaaacagcg cgaggcttgg gacaagttcc aaaaactcaa taccgagctg aaccgtttga
    12181 aaacggaagt cgccgctacg aaagcgcaga tttcccgttt cgtatcgggg aactataaaa
    12241 acagccagcc gaatgcggtt gccctgttcc tgaaaaacgc cgaaccgggt cagaaaaacc
    12301 gctttttgcg ttatacgcgt tatgtaaacg cctccaatcg ggaagttgtc aaggatttgg
    12361 aaaaacagca gaaggctttg gcggtacaag agcagaaaat caacaatgag cttgcccgtt
    12421 tgaagaaaat tcaggcaaac gtgcaatccc tgctgaaaaa acagggtgta accgatgcgg
    12481 cggaacagac ggaaagccgc agacagaatg ccaaaatcgc caaagatgcc cgaaaactgc
    12541 tggaacagaa agggaacgag cagcagctga acaagctctt gagcaatttg gagaagaaaa
    12601 aggccgaaca ccgcattcag gatgcggaag caaaaagaaa attggctgaa gccagactgg
    12661 cggcagccga aaaagccaga aaagaagcgg cgcagcagaa ggctgaagca cgacgtgcgg
    12721 aaatgtccaa cctgaccgcc gaagacagga acatccaagc gccttcggtt atgggtatcg
    12781 gcagtgccga cggtttcagc cgcatgcaag gacgtttgaa aaaaccggtt gacggtgtgc
    12841 cgaccggact tttcgggcag aaccggagcg gcggcgatgt ttggaaaggc gtgttctatt
    12901 ccactgcacc ggcaacggtt gaaagcattg cgtcgggaac ggtaagctat gcggacgagt
    12961 tggacggcta cggcaaagtg gtcgtggtcg atcacggcga gaactacatc agcatctatg
    13021 ccggtttgag cgaaatttcc gtcggcaagg gttatatggt cgcggcagga agcaaaatcg
    13081 gctcgagcgg gtcgctgccg gacggggaag aggggcttta cctgcaaata cgttatcaag
    13141 gtcaggtatt gaacccttcg agctggatac gttgatcgga ttgccgaaac ggtaggcttt
    13201 atgcaaatcg tgccgatatg gtgcgctgtt ccgtgaagtt tgccgtttgc cgtacctgta
    13261 tcttccggtt tttggaaatc aagagagaaa gttaaagaag aatgtcgaaa cctgttttta
    13321 agaaaatcgc actttatact ttgggtgcaa tcagcggcgt ggccgtcagt ctggcggtgc
    13381 agggttttgc cgccgagaag gacaggcggg ataacgaagt cctgccggtg caatccatcc
    13441 gcacaatggc ggaggtttac ggtcaaatca aggcaaacta ctatcaggac aaacccgatg
    13501 ccgatttgtt tgaaggtgcg atgaagggta tggtggccgg tttggatccg cattccgaat
    13561 atatggataa aaaaggttat gccgagataa aggagtccac cagcggcgaa tttggcggct
    13621 tggggatgga aatcgggcag gaagacggat ttgtcaaagt ggtttcgccg attgaggaca
    13681 cgcctgcgga acgggcgggg gtgaaaagcg gcgatttcat tgtgaaaatc gataatgttt
    13741 cgacacgcgg catgacggtc agcgaagcgg tgaagaaaat gcggggcaag ccgggtacga
    13801 agattacttt gacgctgtcg cgcaaaaatg ccgacaagcc gatagtcgtc aacctgaccc
    13861 gtgccattat taaagtgaaa agcgtccgcc atcacctgat cgaacccgat tacggctata
    13921 tccgcgtgtc gcagttccaa gagcggacgg tcgaaagcgt caataccgcc gcaaaagagc
    13981 tgctaaagga aaataaagga aaaccgctca aggggctggt gttggatttg cgcgacgacc
    14041 ccggcgggct tttgactggc gcggtcggcg tgtcggcggc atttctgccg tctgaagcgg
    14101 tcgtcgtcag tacgaaaggg cgggaaggta tggaaggctt tgtgttaaag gcgcgtcccg
    14161 aagattatat ttttaaagcc ggcgcggatc ctttggcggg tattcctgcc gagttgaaaa
    14221 ccataccgat gacggttctg attaattcgg gttcggcttc cgcgtcggag attgtcgcag
    14281 gtgcattgca ggatcataaa cgcgcggtca tcgtcggtac gcagagcttc ggcaaaggtt
    14341 cggttcagac tttgattcct ttgtccaacg gcagcgcggt caagctgaca acggcactgt
    14401 attatacgcc gaacgaccgt tctattcagg cgcaggggat tgttcccgat gtcgaagtaa
    14461 aagataagga acgcattttt gaaagccgcg aggcggattt ggtcggacac atcggcaatc
    14521 ccttgggcgg cgaggatgtg aacggtgaaa cccttgccgt gccgcttgaa aaagatgcgg
    14581 ataagcccgc tgtaaaagaa aaaggtaaaa agaaaaagga cgaggatttg tcttcaaggc
    14641 ggattcccaa ccctgccaaa gacgaccagt tgcggaaagc tttggattta gtcaagtcgc
    14701 ccgagcagtg gcagaagtct ttggggctgg cggcgaaaaa gccggtttca aataaagata
    14761 agaaagataa aaaagataag aagtaggttt tgacgatgcc gtctgaaagg atttcagacg
    14821 gcatattatg tttgaaagga caggttatga gcgatttttt accggaattt gaaccgtgcg
    14881 gcatttatag tggattaaca aaaatcagga caaggcgacg aagccgcaga cagtacaaat
    14941 agtacggcaa ggcgaggcaa cgccgtactg gtttttgtta atccactata cttgggtagc
    15001 gattgggttt cagacggcat acattcagga tttcaccgcc ttatgccgtc tgaaagacgt
    15061 ttccgaccca tccctactac acactttgtc cgcaaacgca tcacaggcaa gattatggaa
    15121 gttatccaat acccaaattc ccccttcaaa ctccaccaac ccttcccgcc cgcaggcgac
    15181 cagcccaccg ccattgcagg cctgctcgaa gggctttcag acggccttgc ctatcaaacc
    15241 ctgctcggcg taaccggttc gggcaaaacc tacaccatgg cgaacgtcat cgcccaaagc
    15301 ggccgacccg ccatcatcat ggcgcacaac aaaacgctgg ccgcccagct ttacgccgaa
    15361 atgcgcgaat tttttcccga aaatgcggtg gaatatttcg tgtcttacta tgattattac
    15421 cagcccgaag cctatgtgcc gagccgtgac ttattcattg aaaaagattc ggcgattaac
    15481 gaacacatcg agcaaatgcg gttgagtgcc accaaaaacc tgatgacgcg caacgacgtg
    15541 attatcgtcg ccaccgtgtc cgcgatttac ggtatcggcg acccgactga atacaagcaa
    15601 atggtgttgt cagtgaaaga aggcgacaca ctcgagcagc gcgacatcat ttctacgctg
    15661 gtatcgatgc agtatgaacg cggcgaaatg gatttcaaac gcggctcatt ccgtgtgcgc
    15721 ggcgatgtga ttgacgtgta tccggcggaa agctcagaaa acgccttgcg tatcagcctg
    15781 ttcgacgacg aaatcgaccg cctcgatatg ttcgacccgc tttcaggcag ccttatccaa
    15841 cgcgtcggcc gctacaccgt cttcccgtcc agccactacg ttaccccgcg cgacaccgtc
    15901 ttgcgcgcct gtgactccat caaagaagaa ttgcgcgacc gcattgaatt ttttgccaat
    15961 gaacaacgcc ccgtcgaaca acaacgcatc gaacagcgta cccgtttcga tttggaaatg
    16021 ctctacgaaa tgggcttctg taaaggaatc gaaaactact cccgccactt ctccggcaaa
    16081 aaagaaggcg aaccgccgcc cacgctgatg gactacctgc ccgacaacgc catcatgttc
    16141 atcgacgaaa gccacgttac cgtcacacaa atcggcggca tgtacaaagg cgacgcatcg
    16201 cgcaagcaaa acctcgtgga ctacggcttc cgcctacctt ccgcccgcga caaccgcccg
    16261 ctcaaattcc acgaatttga aaaagtcatg ccgcaaaccg tcttcgtttc cgccaccccc
    16321 gccaaatacg aagaagaaca cgccggacaa gtggtcgaac aagtcgtccg ccccacaggg
    16381 ctggtcgacc ctcaaatcat catccgcccc gtcgccaccc aagttgatga cttaatgagc
    16441 gaaatcaacg accgcatcca aaaaggcgaa cgcgtactcg ttaccaccct taccaaacgc
    16501 atggcggagc aactcaccga ctattacagc gaactcggca tcaaagggcg ctacctgcac
    16561 agcgacatcg acaccgtaga gcgcgttgaa attattagag atttgcggct cggactgttt
    16621 gacgtactcg tcggcatcaa cctcttgcgc gaaggcctcg acatccccga agtctccctt
    16681 gttgccatcc tcgacgccga caaagaaggc ttcctgcgct cccaccgcag cctgattcaa
    16741 accataggcc gcgccgcgcg caacgtgaac ggcgtcgcca tcctgtacgc cgacaaaatc
    16801 accgactcca tgaaagccgc catcgacgaa accgaacgcc gccgcgaaaa acagattaaa
    16861 ttcaacgaag aacacggtat tgttccgcag cagattaaaa aacaggtcaa agacatcatc
    16921 gacggcgtgt accacgaaga cgacggcggc aaaggccgta gacaaggcaa aaacaaggtt
    16981 aaagtcggcg aaatccacaa cgaagaagac gcgattaaag aaatcgccaa actggaaaaa
    17041 gccatgcagc aggcagctaa ggatttacag tttgaagaag ctgctgtgtt gagggatagg
    17101 atacggggta ttaaagagaa tttgttgttt gaggctgagt aaagtattca tattgattta
    17161 attattaggg taatttatgg aaaagatata tcttgattat caatttatta ttgatgaggt
    17221 tgatgacagg aaaaactgga aactatcaaa tattgatgat aacaaatacc aaattgttta
    17281 ttctcctgcg catatagaag aaatagtgcg tgggaaaaag tgtaataaat taaaaggaaa
    17341 tattttttta tatactaatt atgtaagtaa tcttactaaa gataggcaac taataagaac
    17401 agatgcgtct actgcaaaaa ttttggagaa accttttgga gaaaatggga tatttctagt
    17461 tgaagaaaac cccagatact gctgtcaaag ggtcttaaaa tatttagata aaaatgaaat
    17521 agcagaagaa ggtcaaaaac aaattttgga agatggaaat aggaaattcg aacaatttaa
    17581 tcagaaaaat aggcaaaaaa aggtagtagg aatacagaaa ttaagtattt tagatatttt
    17641 taatagggat gatgatgttt ttaatgaatt tctaactaaa atagtttatt catatatttt
    17701 aaaaaatatt gtatcagaaa atttaaataa atttaattta gataataatt tgtatatgga
    17761 gttgttatgt aaaagtttct tctctaatat caacattaat aataggatag aaaaagaaag
    17821 aaataggttt gaaaaaatat ttcgcgataa agataatatt tttaaagaaa tttcctctga
    17881 acatcattta gttgaaaata ttattgataa tcttatgaaa acattaatga gttgtggatt
    17941 ttatttagaa gcagaaagaa aagccacttc taatttacat gacacaacac attgtatata
    18001 cgctgcgtat agtgattttt ttattactag agacaaaaag ctcaaatata gagtcgaggc
    18061 tatctataaa tatttaggcg tgaaaacaca agtaattttt gtagatagct cagataatga
    18121 agatatttta gtagatagat tcggtaagcc gtagcaagcc gtagcccgct tccccaccaa
    18181 ccgcgtgcat gactgcacca cacactctac ctgcgggcgg cacaaacttt aaaaccgagg
    18241 tgtagggtgt gtgcggtacg cacgtgcgcg ttttgtgccg tttacaccat tgtttcaaac
    18301 tttcagacga cctttgtttc atttcaggca acgaatataa taacgcatag gctgattcct
    18361 accagttgat tcaaagtcca acgataatcc attaaaaaga agaatctgac catcatgacc
    18421 tatccgcaag ccctgcaata acttcaatat tggctcacaa acagccaatt ctctcacaca
    18481 aaccatctaa attttaatgc acatcccctt ttaaccgatg aattgcaggc gatacgcgaa
    18541 tatacgcaaa acagactgcc tgaaagctat tatttatttt tacaacaatg cggcacgggg
    18601 gatttcttct attcatggta caccagcgtg atagatcaaa ccgtatctca aatgcccaaa
    18661 atagaaatct acaacctcac ccaactgaaa gaagaaaata tctattacca acaactatta
    18721 cgcgaagaac ttgatgacat accgcctgac gaacaccccg acataggtaa aatccttatc
    18781 atcggcgcac atcacagcat gggagattgg ttcggctttg acctatcccg tgccgaaccc
    18841 aacttcgata tttttatcca cgatgccgcc aatcacgcca cctatgccga ggaagccgaa
    18901 tggcggcgtt ttgaagactg gattattcgt tgcgtggaaa gcgagggaga agatacgctt
    18961 taaacaagcc gtagcaagag taggtcggat acttgtatcc gacaaaatct ttaatattcc
    19021 tgtcgttgca attcattgca gaaataacca aaatgtcgga ttcgagaatc cgacctacgg
    19081 aaaactaaag attttatgcg tgttacggct tgcttgttgt atttaatcat atttatttga
    19141 attgaattct tttattttat tgtgagatga aaatagtatt ttcgatgaga aacccatgac
    19201 taaaatagta tagtctttat cattctttac gaagtaacaa ttaccatatc ctgcaatatt
    19261 tttatcccaa aaatcacaat atgattcagt agtaaaatta gttttagttg atataaaatc
    19321 aaaattattt gggtaagatc catattgctg gtagtattta tctatatttt ctactaagaa
    19381 atcaattctt ttttctaaca ttttgagatt aatttgtaat aataaaatgt ataaaactat
    19441 actgattgtt attattttta aataagtcat tttattttcc agtaaataga ggtttagttg
    19501 ttttgttaac tatgcctgaa tgtacaccta agtctttgtt taataacgat gaataattag
    19561 caagccgtag cctacatcac accaaccgcg tgcgtagcta tcacatacta cctgcgggcg
    19621 gcacaaactt taaaaccgat gtgcataaaa cctactaagg atgcgtgcgg tacacacgcg
    19681 ttttgccgtt caaaccattg ttttaaaaat tgtatcgaaa catcactcgc tgctttatct
    19741 tgaaaaaatg ccgtctgtaa gcaaacatgc ttcaaacggc atttttttat ccggcggttt
    19801 gttatctgat ccgtttgaat accaagtccc aaacgccgtg cccgaggcgt ttgccgcgca
    19861 cttcgaattt ggtttcgggg cggtagtccg gggtgggggc gtagtctgcc gccgtatttt
    19921 gcaggctgtc gaagctactg aggacttcaa gcatctgctg tgcatattct tcccagtctg
    19981 tcgccaggtg gatatagccg ccggttttga gtttgggcag tagtttggcg atgaaggggg
    20041 tttgtatcag acggcgtttg tggtggcgtt ttttgtgcca cgggtcgggg aagaatatgt
    20101 ggatgccgtc gagcgagccg tcttgcagca tattttcgac aacttctacg gcatcgtgcc
    20161 gcatcacgcg gatgttttcc aaatgatttt cgtctatgag tttgagcagg ttgcctacgc
    20221 cgggaccgtg tacgtcgatg gcgaggaagt cggtttcggg caggcggcgg gcgatttctg
    20281 cggttgccgt ccccataccg aagcctattt cgaggatttt gggccggttg cttccgaaat
    20341 tggcatcaag atcggccggt gttgcttggt aatcgatgcc gaagctgtcc cataaggtat
    20401 cgatggcgcg ttgctgcgcg gcggtcatat ggctttggcg gaggacgaag ctgcggatgc
    20461 tgcgggggtg tccggcttga cggtcgtttg gtgtttggtt ttcggcggtg tctgtcataa
    20521 tgctttcatg cggttgtgca atcaggatgc cgtctgaatg tgaaatgtct gttcggacgg
    20581 cgggaaggga aaggggcgat tatacctgtt tcgtttttgc ggggtaaatg taccggtgtt
    20641 cagacggcat tttgccactg ttgcaacagt tcttgcagaa agcttttttg ttcgtgtccg
    20701 ctgtttatgg cttcttgtag gtagcggtag gctttttcgt tgtccggctc gacgccgtgt
    20761 ccgttgtaat ggatgcaggc gaggttataa agtgccatgc tgtctttttg cgcggcggct
    20821 tgctcaaacc atttgcgtgc ttcattgtag tcggcggtca taccctgtcc gaagtaatgc
    20881 atgctgccca gattggtttg ggctttgctg tggccgagtt ctgctgcttc tgtgtagagt
    20941 ttgagcgcgg ctgcgtattc gggcgcgcat tgtaatccgt aatgaagggc ttgggctttt
    21001 tgataaagct gttctgccct ttgccgcttg atggcggaat ctttgatgct gccatattgc
    21061 tcgggatggt ttaacgcgct gtcggatatg agtttctgat aggcggaaag gctgccggct
    21121 tcggctgcct gccggtaata atgccgggct ttttccgtat cgggggctat gcccaaaccg
    21181 tagtggcaga tgtcgcccag tatccgcaaa ccttcgggat ggcgttctgc tgcggctgct
    21241 tcggcatgat gcagggcaag tttgtggttt ctttcctgat atttgccttg taggtagatg
    21301 tcggccagtg cggcatgggc atcggggtca ttttcctgtg ccgcctgttg gaaccggtaa
    21361 acggcttcat cgggagccgt aggtaggatg agttcggcaa gcggggtgta ggcgggaatg
    21421 tatccttgtt gcgcggcggc gcgcaaatga ttgacggcct gtgccgtgtc gactttcgtc
    21481 ccttgcccga aacggtattg aaggccgagc tgccattgtg ccgccgccaa gccttgtgcc
    21541 gccgctttgc ggtagagcag gtgcgccgtt tcaaaatccg gcggtgtgcc gtaccggcag
    21601 tattgggcga gcaggtattg cccgtgggga ttgttgtttt ttgcgcttgt ttttgcccat
    21661 ttcatttcag ggcttcttca aaatgtcggg acgcatacag caggtacatc aggcggactt
    21721 gtgcttcagg cagcccttcc tctgccaacg gtctgtaaag cggtttcagg gtttcagggg
    21781 gtgcaccttc caattcttgg atatatgcca gattgtaacg cgcgtaggga tgtccctgtt
    21841 cggcggcgat gcggagcatt tccatacctt gttcgcggtc ttggtagggg ctgtccgcgt
    21901 ccatcaggtg ttttgccaac tcgaatgcgg cggcgggatg acctgccgag gccgcttctg
    21961 tcagcagtcg gcggacttcg gtaaagttat attgtttttg agacaggcgt tctaaggcct
    22021 gccgataggg taagtcggga ttgttcatat caggtcgttt tccgttttgt caaatcatcg
    22081 ttattgtgtt atgaagttag
//
LOCUS       DAXIDM010000026        21480 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000026 DAXIDM010000000
VERSION     DAXIDM010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 21480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21480
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.026"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(590..1174)
                     /gene="rnhB"
                     /locus_tag="ACFOAE_000796"
     CDS             complement(590..1174)
                     /gene="rnhB"
                     /locus_tag="ACFOAE_000796"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFC6884317.1"
                     /translation="MHILTAGVDEAGRGPLVGSVFAAAVILPETFDLPGLTDSKKLSE
                     KKRDALAEMIKNQAVAWHVSAATPEEIASLNILHATMLAMKRAVDGLAVRPEKIFIDG
                     NRIPEHLNIPAEAVVKGDSKIIEISAASVLAKTARDAEMYALAQRHPQYGFDKHKGYG
                     TKQHLEALEKYGVLPEHRRDFAPVRNLLAQQTLF"
     gene            complement(1243..3138)
                     /gene="mnmG"
                     /locus_tag="ACFOAE_000797"
     CDS             complement(1243..3138)
                     /gene="mnmG"
                     /locus_tag="ACFOAE_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFC6884318.1"
                     /translation="MTHMIYPKTYDVIVVGGGHAGTEAALAAARMGAQTLLLTHNIET
                     LGQMSCNPSIGGIGKGHLVRELDALGGAMALATDKSGIQFRRLNASKGAAVRATRAQA
                     DRILYKAAIREMLENQENLDLFQQAVEDVTLDGDRISGVITAMGVEFKARAVVLTAGT
                     FLSGKIHIGLENYEGGRAGDPAAKSLGGRLRELNLPQGRLKTGTPPRIDGRTIDFSQL
                     TEQPGDTPVPVMSVRGNAEMHPRQVSCWITHTNTQTHDIIRSGFDRSPMFTGKIEGVG
                     PRYCPSIEDKINRFADKDSHQIFLEPEGLTTHEYYPNGISTSLPFDIQIALVRSMKGL
                     ENAHILRPGYAIEYDYFDPRNLKASLETKTIAGLFFAGQINGTTGYEEAAAQGLLAGA
                     NAVQYVREQDPLLLRREQAYLGVLVDDLITKGVNEPYRMFTSRAEYRLQLREDNADMR
                     LTEDGYKIGLVGEAQWRMFNEKREAIEREIQRLKTTWYTPQKLAEDEQIRVFGQKLSR
                     EANLHDLLRRPNLDYAALMTLEGAMPSERLSAEVVEQVEIQVKYQGYIDRQNEEIDSR
                     RDIETLKLPDGIDYGKVKGLSAEVQQKLNQHKPETVGQASRISGVTPAAVALLMVHLK
                     RGFKDAK"
     gene            complement(3463..4890)
                     /locus_tag="ACFOAE_000798"
     CDS             complement(3463..4890)
                     /locus_tag="ACFOAE_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HFC6884319.1"
                     /translation="MNENFTEWLHGWVGAINDPMWSYLVYMLLGTGLFFTVTTGFVQF
                     RLFGRSIKEMLGGRKQGDDPHGITPFQAFVTGLASRVGVGNIAGVAIAIKVGGPGAVF
                     WMWVTALIGMSSAFVESSLAQLFKVRDYDNHHFRGGPAYYITQGLGQKWLGVLFALSL
                     IFCFGFVFEAVQTNTIADTVKAAWGWEPHYVGVALVILTAPIIFGGIRRISKAAEIVV
                     PLMAVLYLFIALFIILTNIPMIPDVFGQIFSGAFKFDAAAGGLLGGLISQTMMMGIKR
                     GLYSNEAGMGSAPNAAAAAEVKHPVSQGMIQMLGVFVDTIIVCSCTAFIILIYQQPYG
                     DLSGAALTQAAIVSQVGQWGAGFLAVILFMFAFSTVIGNYAYAESNVQFIKSHWLITA
                     VFRMLVLAWVYFGAVANVPLVWDMADMAMGIMAWINLVAILLLSPLAFMLLRDYTAKL
                     KMGKDPEFKLSEHPGLKRRIKSDVW"
     gene            5050..6039
                     /gene="pdxA"
                     /locus_tag="ACFOAE_000799"
     CDS             5050..6039
                     /gene="pdxA"
                     /locus_tag="ACFOAE_000799"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HFC6884320.1"
                     /translation="MKQPVFAVTSGEPAGIGPDICLDLAFARLPCRCAVLGDKNLLRA
                     RAEALGKSVVLRDFDPESGGAAYGELEVLHIPAVEAVEAGKLNPANAAYVLQLLDTAL
                     AGISDGIFDGIVTAPLHKGIINDARASTGFFSGHTEYLAEKSGTGQVVMMLAGKGLRV
                     ALVTTHLPLKDVAAAITQPLIESVARILHHDLKHKFCIKNPKILVAGLNPHAGEGGHL
                     GHEETDTIIPALENLRREGINLAGPYPADTLFQPFMLEGADAVLAMYHDQGLPVLKYH
                     SFGQGVNITLGLPFIRTSVDHGTALDLAATGRADSGSLITAVETAVEMARGSL"
     gene            complement(7364..10123)
                     /locus_tag="ACFOAE_000800"
     CDS             complement(7364..10123)
                     /locus_tag="ACFOAE_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HFC6884321.1"
                     /translation="MKRMLFNATQAEELRVAIVDGQNLLDLDIETLGKEQRKGNIYKG
                     IITRIEPSLEACFVDYGTDRHGFLPFKEVSRSYFQDYEGGRARIQDVLKEGMEVIVQV
                     EKDERGNKGAALTTFISLAGRYLVLMPNNPRGGGVSRRIEGEERQELKAAMAELDIPN
                     GMSIIARTAGIGRSAEELEWDLNYLKQLWQAIEEAGKAHHDPYLLFMESSLLIRAIRD
                     YFRPDIGEILVDNQEVYDQVAEFMSYVMPGNIGRLKLYEDHTPLFSRFQIEHQIESAF
                     SRSVSLPSGGAIVIDHTEALVSIDVNSARATRGSDIEDTAFKTNMEAAEEVARQMRLR
                     DLGGLVVIDFIDMENPKHQRDVENVLRDALKKDRARVQMGKLSRFGLLELSRQRLKPA
                     LGESSHVACPRCAGTGVIRGIESTALHVLRIIQEEAMKDNTGEVRAQVPVDVATFLLN
                     EKRAELFAMEERLDVNVVLIPNIHLENPHYEINRIRTDDVEEDGEPSYKRVAEPEEDE
                     SAKPFGGEKAKAARPEPAVKGVRHTSPAPTAAPEKKTSWWDSFKAWLKRIFGGSETQA
                     ASAAETSEKRSTANRSGSRVNNRRQNPRRSKREGSKVEVREVAGKTAGQEARADKAET
                     RNNGNRRRNERGDRAAERANEAEIQGRNVQPAATVADAAPSETEVQTSKRRRNGSRSE
                     RGQTAPETATVAETTVQTAENTPSEPHTAEDKGSKPKSERNRRERDSRDAKERRERNN
                     QRDRRQNGKKRNIPSAAKIEQYLNIHDTADKVRSAAAHVFGETDANAPITVSIADPVA
                     ERDLPTASPAVSNGDAPVYDAAEKIRRATAAILPEGATPKAEAQEMPSETATFTAAAE
                     QARETAQTGGLVLIETDPAALKAWAAQPEVQAGRGLRRSEQPKPSEVATVPAEEMIQV
                     ETRQG"
     gene            10617..11609
                     /locus_tag="ACFOAE_000801"
     CDS             10617..11609
                     /locus_tag="ACFOAE_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFC6884322.1"
                     /translation="MKTHEISKDSVSLIGVAEHEAGQRLDNYLIKILKGVPKSHIHRI
                     IRAGEVRLNKKRCKPDSRIAEGDTVRIPPVRVAEKEMPSERRAAVPARAFEAVYEDDA
                     LLVIDKPSGVAVHGGSGVSFGVIEQLRRARPEARYLELVHRLDKDTSGLLMVAKKRSA
                     LVKLHEAIRNDHPKKIYLALGVGKLPDDNFHVRLPLSKYTGAQGEKMVRVSADGQSAH
                     TVFRVLSRFSDGILHGVGLSHLTLVRATLKTGRTHQIRVHLQSQGCPIAGDERYGDYQ
                     ANRRLQKLGLKRMFLHASELHLNHPLTGEPLVLKVGLPPDLAQFAVMLENGTKM"
     gene            11657..12829
                     /gene="lpxB"
                     /locus_tag="ACFOAE_000802"
     CDS             11657..12829
                     /gene="lpxB"
                     /locus_tag="ACFOAE_000802"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008915 - lipid-A-disaccharide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HFC6884323.1"
                     /translation="MWGQTNMADKKSPLIAVSVGEASGDLLGAHLIRAIRKRCPQARF
                     VGIGGELMKAEGFESLYDQERLAVRGFVEVVRRLPEILRIRRGLVRDLLSLKPDVFVG
                     IDAPDFNLGVAERLKRSGIPTVHYVSPSVWAWRRERVGKIVHQVNRVLCLFPMEPQLY
                     LDAGGRAEFVGHPMAQLMPLEDDRETARKTLGVDAGIPVFALLPGSRVSEIDYMAPVF
                     FQTALLLLERYPAARFLLPAATEATKRRLAEVLQRPEFAGLPLTVTDRQSETVCRAAD
                     AVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKIKVPHVGLPNILLGKEAVPEL
                     LQSEAKPEKLAAALADWYEHPDKVAALQQDFRALHLLLKKDTADLAARAVLEEAGC"
     gene            12837..12995
                     /locus_tag="ACFOAE_000803"
     CDS             12837..12995
                     /locus_tag="ACFOAE_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884324.1"
                     /translation="MDYFPEAARITKKGGEIVINGTSNNKYLRGIPNETELARMGLRL
                     KYNGQLTD"
     gene            complement(13039..13428)
                     /locus_tag="ACFOAE_000804"
     CDS             complement(13039..13428)
                     /locus_tag="ACFOAE_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF596 domain-containing protein"
                     /protein_id="HFC6884325.1"
                     /translation="MNVKIKYNLLEYCEYLGGIFGVYKNYLNMDIKDPNLKIRFFDFL
                     EELLSDGVIELCDYRENPPKILTGSPKTQVDELRRIWPDMEEMLLYFPDNPWFYVEHF
                     WWGATCPIELTQLPKIEIYEEQMKQGK"
     gene            13651..14061
                     /locus_tag="ACFOAE_000805"
     CDS             13651..14061
                     /locus_tag="ACFOAE_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884326.1"
                     /translation="MTTYTIPKKDYQFLYIYEGTLLNYTLKNDEFHIIVNCVDYPDLP
                     QEIPMPNYSDWVKIKFKQFSYLKFVYGYATKNRDKDIDNTLELGELKQDDEILDYGGA
                     LELIGGRCDLLTGFSIDIVCREIELEFLDQEGFN"
     gene            complement(14325..15134)
                     /gene="dapB"
                     /locus_tag="ACFOAE_000806"
     CDS             complement(14325..15134)
                     /gene="dapB"
                     /locus_tag="ACFOAE_000806"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFC6884327.1"
                     /translation="MTPLKIAIAGANGRMGRVLVEAVNNHPDTVLSGALEHSGSEALG
                     LDAGYAVGLKTGIAISDDVDAVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTG
                     FDDAGKAAIHTAAEQTGIVFAANFSVGVNLTFHILDTVARVLNEGYDIEIIEGHHRHK
                     VDAPSGTALRMGEVIAGALGRDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHT
                     ALFATDGERVEITHKASSRMTFAAGAVRAAVWVNGKTGLYDMQDVLGLNNR"
     gene            complement(15144..15521)
                     /locus_tag="ACFOAE_000807"
     CDS             complement(15144..15521)
                     /locus_tag="ACFOAE_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HFC6884328.1"
                     /translation="MNKTLILALSALLGLAACSAERASLFPSYKLKVIQGNEIDPRAA
                     AALRLGMTKDQVLLLLGSPLLRDAFHTDRWDYTFNTSRNGIIKERSNLTVYFENGVLV
                     RTEGDALQNAAEALKDRQNTDKP"
     gene            15740..16174
                     /gene="fur"
                     /locus_tag="ACFOAE_000808"
     CDS             15740..16174
                     /gene="fur"
                     /locus_tag="ACFOAE_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HFC6884329.1"
                     /translation="MEKFNNIAQLKDSGLKVTGPRLKILDLFETHSEEHLSAEDVYRI
                     LLEEGVEIGVATIYRVLTQFEQAGILQRHHFETGKAVYELDKGDHHDHIVCVKCGEVT
                     EFHNPEIEALQDKIAEENGYRIVDHALYMYGVCSDCQAKGKR"
     gene            16244..16969
                     /gene="aat"
                     /locus_tag="ACFOAE_000809"
     CDS             16244..16969
                     /gene="aat"
                     /locus_tag="ACFOAE_000809"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008914 - leucyl-tRNA--protein transferase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HFC6884330.1"
                     /translation="MRIPLLAPDNYAFPDPAYALARCDGLVGVSGDLDAGRLLEAYRN
                     GVFPWFSRDGWFFWYAVGPRAVVFPDRLHIPRSLAKTLRNGSYRVAVNGCFAEVVAHC
                     AAAARPNQDGTWIAPEFQTAYLKLHEMGHAHSFECHYPDESGETRLAGGFYGVQIGSV
                     FYGESMFALQPDASKIAFACAVPFLADLGVELIDCQQDTGHMRRFGSELLPFADFAER
                     LRMLNAVPLKEEIGRREVACKGL"
     gene            complement(17216..18247)
                     /gene="gap"
                     /locus_tag="ACFOAE_000810"
     CDS             complement(17216..18247)
                     /gene="gap"
                     /locus_tag="ACFOAE_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFC6884331.1"
                     /translation="MGIKVAINGYGRIGRQVLRAIYDYQIQDQLQIVAVNASGSLETN
                     AHLTKFDTVHGRFEADVSHDGGNLIVNGDKIPFFSTRNPAELPWKELGVDLVMECTGA
                     FTSKEKAKVHLESGAKKVLISAPGGDDVDATVVYGVNDSILTADMTVVSNASCTTNCL
                     SPVAKVLSESVGIVKGAMTTIHALTNDQTVTDVRHKDLRRARSGVENMIPTKTGAAKA
                     VGLVLPELKGKLDGLAIRVPTINVSLVDLSFQAARDTTVEEINALMKAASEAGALKGV
                     LGYNTLPLVSMDFNHTTEASHFDATLTKVVDGNMIKVFAWYDNEWGFSCQMLNTARRM
                     FGLEVRPLK"
     gene            complement(18448..19287)
                     /locus_tag="ACFOAE_000811"
     CDS             complement(18448..19287)
                     /locus_tag="ACFOAE_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HFC6884332.1"
                     /translation="MTATAAAIDRLLPQTQCRECGYDGCLPYAQAVATGEAYNLCAPG
                     GEAVIRDISALLGKPLVAPAKTQAKALARIDETACIGCTACIRACPADAIMGAGKLMH
                     TVIADECTGCGLCVAPCPVDCIHMQPVADTVLPRARRFSLSADSRFAAAEHARARYLK
                     RNERKQREADERKAMLAEREAAVRNARPQTPDTPKKPAFNPADLIAKAMAKAQTQQDR
                     LAAADNRKDYQAKQIAEARERAELRRAQRDMKYGSDSEKAAALEYLKQYKAKQEAAQN
                     TAS"
     gene            19436..21412
                     /locus_tag="ACFOAE_000812"
     CDS             19436..21412
                     /locus_tag="ACFOAE_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFC6884333.1"
                     /translation="MNEFSLAPIVVVLLVSVITVILCRKFNIPSMLGYLLVGFLAGPG
                     MLSLIPKSHATDYLGEIGIVFLMFSIGLEFSLPKLRAMRRLVFGLGGLQVGVTMLSVM
                     GILMLTGVPFNWAFAVSGALAMSSTAIVSRILSEKTELGQPHGQMAMGVLLMQDIAVV
                     PLMILIPALAGGGDGNIWAALGLAFAKMLLTLGLLFFVGSKIMSRWFRMVAKRKSSEL
                     FMINVLLVTLGVAYLTELEGLSMALGAFVAGMLLSETEYRFQVEDDIRPFRDILLGFF
                     FITVGMKLDIQALIGGWRQVLMLLAMLLVLKALVVFAIAFKMKHSVGDSLKTALYLAQ
                     GGEFGFVMLAIAGQLDMVSPEWEQAATAAVLLSMIIAPFLLGGSDALVGRLVKSSWDM
                     KSLDLHSMLVETMSKSDHVLIVGFGRGGQTVGRVLAQEDIPYFALDLDIARVQVARSA
                     GEPVSFGDAKRREVLEAAGLGRAKMVVVTLNNMHETQHVLDNVLSMYPNMPVYVRATN
                     DDYVKTFTDIGAEEAVSDTKETGLVLAGYAMLGNGASYRHVYQTMANIRHSRYAALEG
                     LFVGSDDEAGFGETGETVRHAFPLAAEAYAVGKTVGTLPMAAYGIKLLFVRRRTGRIE
                     NPDASFTLEGGDVLVVAGKKEEIISFENWSLQGI"
BASE COUNT         4302 a         5129 c         6596 g         5453 t
ORIGIN      
        1 tcattcccgc aaaaacaaaa aaatcaaaaa cacaaaactg aaatatcgtc attcccgcgc
       61 aggcgggaat ctaggtctgt cggtacggaa acttatcggg aaaaacggtt tttccaaccc
      121 tgagactccg gattcctgtt ttcgcgggaa tccggttttt tgagtttcag tcatttttga
      181 taaattcttg cagctttgag tttctagatt cccgcttttg cgggaatggc ggtttggaag
      241 tttcccgaaa ttcaaaaaaa acggaaaccg gacggattgg attcccgcct gcgcgggaat
      301 gacggatttt aggtttcttt tttgagtttc agtcattttt gataaattct tgcagctttg
      361 agtttctaga ttcccgcttt cgcgggaatg acggtttgga agttacctga aattcaaaaa
      421 aaaacggaaa ccggacggat tggattcccg tctgctcggg aatgacggat tttaggtttc
      481 ttttttgatt ttctgttttt cgcgggaatg acggtttggg ttctttctct ttgaagttgc
      541 gatgctgaaa atgccgtctg aaggcttcag acggcatttt tgtgtcggtt taaaacagcg
      601 tctgctgcgc gagcaggttt ctgacggggg cgaagtcgcg gcggtgttcg ggcagcacgc
      661 cgtatttttc gagggcttcc aaatgctgct tcgtgccgta acctttgtgt ttgtcgaaac
      721 cgtattgggg atggcgttgc gccagtgcgt acatttccgc atcgcgggcg gtctttgcca
      781 aaacggatgc ggcggatatt tcgatgattt tgctgtcgcc tttgacgacg gcttcggcag
      841 ggatgttcaa atgttcggga atgcggttgc cgtcgatgaa tattttttcg ggacgcacag
      901 ccaaaccgtc aacggcgcgt ttcatcgcga gcatggtggc gtgcaggatg ttgaggctgg
      961 cgatttcttc gggcgtggcg gcggagacgt gccacgcaac cgcctgattt tttatcattt
     1021 cggcaagcgc gtcgcgtttt ttctcgctga gttttttgga gtcggtcagt ccgggcaggt
     1081 cgaatgtttc cggaaggatg acggcggcgg caaacacgct gccgactaaa ggtccgcgtc
     1141 ctgcctcgtc cacgccggcg gtcagtatgt gcatgatgtt tcctgtcggg atggtgggaa
     1201 tgccgtctga acggtgtttc agacggcatc gtaccgatgt gtttatttcg cgtctttaaa
     1261 tccgcgcttc aaatgcacca tcagcagtgc gacggcggca ggcgttacac cggaaatgcg
     1321 gcttgcctgc ccgacggttt caggtttgtg ctggttgagc ttttgctgca cttctgccga
     1381 taagcctttg actttgccgt aatcgatgcc gtcgggcagt tttaaggttt cgatgtcgcg
     1441 gcggctgtcg atttcttcgt tttggcggtc gatatagcct tggtatttga cttggatttc
     1501 gacttgttcg accacttcgg cggagaggcg ttcagacggc atcgcgcctt cgagcgtcat
     1561 cagcgcggcg tagtcgaggt tcgggcggcg caggaggtcg tgcaggttgg cttcgcggct
     1621 gagcttttgc ccgaatacgc ggatttgttc gtcttcggcg agtttttgcg gcgtgtacca
     1681 cgttgttttc aaacgttgga tttcgcgttc gatggcttcg cgtttttcgt tgaacatgcg
     1741 ccattgcgct tcacccacca agccgatttt gtagccgtct tcggtcaggc gcatatcggc
     1801 gttgtcttcc ctgagttgca ggcggtattc ggcacggctg gtgaacattc ggtagggttc
     1861 gttcacgcct ttggtgatga ggtcgtccac caatacgccg agataggctt gttcgcggcg
     1921 cagcaggagc gggtcttgtt cgcggacgta ttgcacggcg ttcgcgcctg ccagcagtcc
     1981 ttgcgcggcg gcttcttcat aacctgtcgt accgttgatt tgcccggcga aaaacaatcc
     2041 ggcaatggtt ttggtttcga ggcttgcttt gaggttgcgc ggatcgaagt agtcgtattc
     2101 gatggcgtag ccggggcgca ggatatgggc gttttccaaa cctttcatac tgcggacgag
     2161 cgcgatttgg atgtcgaacg gcaggctggt ggagataccg ttggggtagt attcgtgcgt
     2221 agtcaggcct tcgggttcta ggaaaatctg gtggctgtct ttgtcggcga agcggttgat
     2281 tttgtcttcg atagacggac aataacgcgg gcccacgcct tcgattttgc cggtaaacat
     2341 cgggctgcgg tcgaagcctg agcggatgat gtcgtgggtt tgcgtgttgg tatgcgtaat
     2401 ccagcaggac acttggcgcg ggtgcatttc ggcgttgccg cgtacggaca tgacgggaac
     2461 gggcgtgtcg ccgggctgtt cggtcagttg ggagaagtca atcgtgcgtc cgtcgatgcg
     2521 cggcggcgtg ccggttttca gacggccttg cggcaggttc aattcgcgca aacgtccgcc
     2581 cagcgatttg gcggcggggt cgccggcgcg tccgccctcg tagttttcca aaccgatgtg
     2641 gattttgccg gacaaaaacg tgcctgcggt caacaccacg gcgcgtgctt taaactccac
     2701 gcccatcgcg gtgattacgc ctgaaatgcg gtcgccatcg agcgttacgt cttcgacggc
     2761 ttgttggaaa aggtcgaggt tttcttggtt ttccaacatt tcgcggatgg cggctttata
     2821 taggatacga tccgcctgcg cgcgcgtggc ccgtactgcc gcgcctttgc tggcgttcag
     2881 acggcggaac tggatgccgg atttgtcggt tgccaacgcc atcgcgccgc cgagcgcgtc
     2941 gagttcgcgc accaaatgcc ctttgccgat gccgccgatg gaagggttgc acgacatttg
     3001 tccgagcgtt tcaatattgt gtgtgagcaa aagcgtctgc gcgcccatac gggcggcggc
     3061 gagcgcggct tctgtgccgg cgtgtccgcc gccgacgacg ataacgtcgt aggttttggg
     3121 gtaaatcatg tgggtcatgt gtgtattgcc tgacggtgtt tcagacggca tttatagtgg
     3181 attaacaaaa accagtacag cgttgcctcg ccttagctca aagagaacga ttctctaagg
     3241 tgctgaagta ccaagtgaat cggttctgta ctatctgtac tgtctgcggc ttcgccgcct
     3301 tgtcccgatt tttgttaaac cactatattc aatatgccgt ctgaaaaacg aaatggattc
     3361 aaaagtaaag ggttgggatt gtacgcttgt tcgccctgtt tttacagtgt gcggaaaggg
     3421 aaaagccgct tcgcggggaa gcggctccgg taagggcggg atttaccaaa cgtcggattt
     3481 gatacggcgt ttcaggcccg gatgttcgga aagtttgaac tcggggtctt tgcccatttt
     3541 cagcttggcg gtgtaatcgc gcagcagcat aaacgccagt ggcgagagca gcaggatggc
     3601 gacaaggttg atccacgcca taatgcccat cgccatatcc gccatatccc agaccaaagg
     3661 cacattggca accgcgccga aatagaccca cgccaaaacc agcatacgga aaacggcggt
     3721 aatcagccaa tggcttttga tgaattggac gttggactcg gcataggcat agttgccgat
     3781 aacggtggaa aaggcaaaca taaacaggat gacggcgagg aagcccgcgc cccattgccc
     3841 cacttggctg acaatcgccg cctgcgtcag cgccgcaccg ctcaaatcgc cgtaaggctg
     3901 ttggtaaatc aagatgatga aggcggtgca agaacaaacg atgatggtat cgacaaacac
     3961 gcccagcatt tgaatcatac cttgcgaaac agggtgtttc acttcggcgg cggcggcggc
     4021 gttcggcgcg gaacccatac ccgcctcgtt ggaatacagg ccgcgtttga tgcccatcat
     4081 catcgtttgc gaaatcagac cgccgagtaa gccgcctgct gccgcgtcga atttgaacgc
     4141 gcccgaaaaa atctgaccga acacgtccgg aatcatcgga atattggtca aaatgatgaa
     4201 aagcgcgata aagaggtaca aaaccgccat cagggggacg acgatttccg ccgctttaga
     4261 tatgcgcctg atgccgccga agataatcgg cgcggttaaa atcaccaggg cgacgccgac
     4321 ataatgaggc tcccaacccc acgccgcttt gacggtatcg gcaatggtat tggtctgaac
     4381 cgcttcaaac acaaagccga aacagaaaat caggctcagg gcgaacaaca cgcccagcca
     4441 tttctgcccc agcccttgag tgatgtagta ggcagggccg ccccggaaat ggtggttgtc
     4501 gtagtcgcgg actttaaaga gctgcgccag cgaagattcg acaaacgccg aactcatacc
     4561 gattaaggcg gttacccaca tccaaaacac cgcgcccggt ccgccgactt tgatggcgat
     4621 ggccacgccc gcgatattgc ccacgcccac gcggctggca aggccggtta caaatgcctg
     4681 aaacggcgtg atgccgtgag ggtcgtcccc ctgtttgcgg ccgccgagca tttctttgat
     4741 gctgcgcccg aacaggcgga attggacaaa gcccgtggtt acggtgaaga aaagccccgt
     4801 acccaaaagc atataaacca agtatgacca catcggatcg ttgatggcgc cgacccagcc
     4861 gtgcagccat tcggtaaagt tctcgttcat atcgcttcct taaagttgaa actcgcacat
     4921 attggcggta tgcaagcagg gtttaaattt tgtaaacgcc cattctagca gattgtcaac
     4981 aaaatcagaa aaatttacat cgccgcgcgg ctgcggcgtt agaatcgcat tttgtttgga
     5041 gcaaacacga tgaaacagcc tgtttttgcc gttacttccg gcgagcctgc cggcatcggc
     5101 cccgatattt gtttggactt ggcgtttgca cgcctgccct gccgctgcgc ggtattgggc
     5161 gacaaaaacc tattgcgcgc gcgcgccgaa gccttgggca aaagcgtcgt cctgcgcgac
     5221 ttcgatccag aatcaggcgg cgcggcatac ggcgagctgg aagtgctgca catccctgcc
     5281 gtcgaagcgg ttgaggcggg caaactcaat cccgccaacg ccgcctatgt gctgcaactt
     5341 ttggacaccg cgctcgcagg catttcagac ggcattttcg acggcatcgt taccgcgccg
     5401 ctgcacaaag gcatcatcaa cgacgcgcgc gcaagcacag gttttttcag cggacacacc
     5461 gaatatctgg cggaaaaaag cggcacgggg caggtcgtga tgatgcttgc cggcaaaggc
     5521 ctgcgcgtcg ccctcgtaac gacccacctg ccgctgaaag acgttgccgc cgccatcacg
     5581 caaccgctga ttgaaagcgt cgcacgcatt ttgcatcacg acttaaaaca caaattctgc
     5641 atcaaaaatc ccaaaatcct ggtcgccgga ctcaaccccc acgccggtga gggcggacac
     5701 ctcggacacg aagaaaccga caccattatc cccgcgctcg aaaacctgcg ccgcgaaggg
     5761 ataaacctcg ccggcccgta tccggcggat accttgttcc aaccgtttat gctcgaaggt
     5821 gcggatgccg tattggcgat gtaccacgac caagggctgc ccgtgttgaa ataccacagt
     5881 ttcgggcagg gcgtgaacat cacactgggg ctgcccttta tccgcacctc cgtcgatcac
     5941 ggcaccgcgc tcgatttggc ggcaaccggc agggcggatt ccggcagcct gataactgcc
     6001 gtggagaccg ccgtcgagat ggcgcgcggc agcctttaaa gatgataaaa gacccgtcat
     6061 ttccgcgcag gcgggaatcc ggtctgttcg gtttcagttg tttttgggtt tcgggtaatt
     6121 tccaaatcgt cattcccgcg caggcgggaa tccagacctt cgggcgacgg caatattcaa
     6181 agattatctg aaagtttgag gttctagatt cccgttttca cgggaatgac gaaaggttgc
     6241 gggaatccgg cttgttcggt ttcggttttt tttgaggttt cgggcaactt ctaaaccgtc
     6301 attcccgcgc aggcggaaat ccaggccttt gggcgacggc aatattcaaa gattatctga
     6361 aagtttagag gttctagatt cccgttttca cgggaatgac ggaatgttgt gggaatccgg
     6421 cttgttcggt ttcggttttt ttgaggtttc gggcaacttc taaaccgtca ttcccgcgca
     6481 ggcgggaatc cagaccattg gacagcggca atattcaaag attatctgaa agtttagagg
     6541 ttctagattc ccgttttcac gggaatgacg gaatgttgcg ggaatccggc ttgttcggtt
     6601 tcggtttttt ttgaggtttc gggcaacttc taaaccgtca ttcccgcgca ggcgggaatc
     6661 caggcctttg ggcgacggca atattcaaag attatctgaa agtttagagg ttctagattc
     6721 ccgttttcac ggaaatgacg aaatgttgtg ggaatccaga ccttcgggcg gcggcaatat
     6781 tcaaagatta tctgaaagtt tagaggttct agattcccgt tttcacggga atgacggaat
     6841 gttgtgggaa tccagacctt tgggcggcgg caatattcaa agattatccg aaagtttgag
     6901 gttctagatt cccgttttca cgggaatgac gaaatgttgc gggaatctgg cttgttcggt
     6961 ttcggttttt tttgagattt cgggcaattt ctaaaccgtc attcccgcgc aggcgggaat
     7021 ccagaccttt gggcggcggc aatattcaaa gattatctga aagtttgagg ttctagattc
     7081 ccgttttcac gggaatgacg aaaggttgtg ggaatctaga cctttgggcg gcggcaatat
     7141 tcaaaaatta tctgaaagtt tagaggttct agattcccgt tttcacggga atgacggaat
     7201 gttgcgggaa tcatgggaat gacggaatgt tgcgggaatc atgggaatgg aggaatgttt
     7261 cggtaatcac gggaatggcg aagtttcaga cggcattgca ggtatccgaa cccatgtaaa
     7321 aaagaggttc tgcggaacag aacctctttt tgccgccgtc ggttcagcct tgccgggttt
     7381 cgacttggat catttcttcg gcagggacgg ttgcgacttc agacggcttg ggctgttcgg
     7441 aacggcgcaa accgcgtccg gcttggactt cgggttgtgc cgcccatgcc ttcaatgcgg
     7501 cagggtcggt ttcgatcagg acgagtccgc cggtttgtgc ggtttcccgt gcctgttccg
     7561 ccgcagccgt aaaggttgcg gtttcagacg gcatttcctg tgcttcggct ttcggtgtcg
     7621 cgccttcggg caggatggcg gcggtggcac ggcggatttt ttccgccgca tcataaaccg
     7681 gtgcgtcgcc gtttgaaacg gcgggagatg ctgtcggaag atccctttct gcaaccggat
     7741 cggcaatgct gacggtaatc ggcgcgtttg cgtcggtttc gccgaaaacg tgcgcggcgg
     7801 cggaacggac tttgtcggcg gtgtcgtgaa tattcaggta ctgctcgatt ttggcggcag
     7861 acggaatatt gcgttttttg ccgttttgac ggcggtcgcg ctgattgttg cgctcgcggc
     7921 gttctttggc atctcggctg tcgcgttcgc ggcggttgcg ttcggatttg ggcttgctgc
     7981 ctttgtcttc tgcggtatgc ggttcggacg gcgtgttttc cgctgtctga acggttgttt
     8041 cggcaacggt ggcggtttcc ggcgcggttt ggccgcgttc gctgcggctg ccgttgcggc
     8101 ggcgtttgct ggtttgcact tcggtttcgg acggtgcggc atctgcaacg gttgcggcag
     8161 gctgtacgtt gcgaccttgg atttccgctt cgttggcgcg ttcggcggca cggtcgccgc
     8221 gttcgttgcg gcggcggttg ccgttgttgc gcgtttcggc tttgtcggcg cgcgcttcct
     8281 gtccggcagt tttgcctgcc acttcgcgga cttctacttt gctgccttcg cgtttgctgc
     8341 ggcgcgggtt ttggcggcgg ttgttgacgc ggctgccgct gcggtttgcc gtgctgcgtt
     8401 tttcggaggt ttcggcagcg gacgcggctt gggtttcgct gccgccgaaa atgcgtttga
     8461 gccaagcttt gaagctgtcc caccaggagg tttttttctc gggggcggca gtcggggcgg
     8521 ggctggtgtg gcgcacgcct ttgacggcgg gttcggggcg ggcggctttg gctttttcgc
     8581 cgccgaacgg tttggcggat tcgtcttctt caggctcggc gacgcgcttg tagctcggtt
     8641 cgccgtcttc ttctacgtcg tcggtgcgga tgcggttgat ttcgtagtgc gggttttcga
     8701 ggtggatgtt cggaatcagg acgacgttga catccaaacg ctcttccatc gcaaacagct
     8761 cggcgcgttt ttcgttcagc aggaaggtgg cgacatcgac gggcacttgg gcgcgcactt
     8821 ctccggtgtt gtccttcatc gcttcttctt gaatgatgcg taaaacgtgc agggcggtgg
     8881 attcgatgcc ccgaatcacg ccggtgccgg cacagcgcgg acacgcaaca tggctgcttt
     8941 cgcccaaagc cggtttcaaa cgttggcggc tcaattccaa aaggccgaaa cgggacagtt
     9001 tgcccatctg cacgcgggcg cggtcttttt tgagcgcgtc gcgcaggacg ttttccacat
     9061 cgcgctggtg tttggggttt tccatatcga tgaagtcgat gacgaccaaa ccgcccaagt
     9121 cgcgcaggcg catttgtcgg gcgacttctt cggcggcctc catattggtt ttgaacgcag
     9181 tgtcttcaat gtcagatccg cgtgtggcac gtgcagagtt aacgtcgatg gagacgaggg
     9241 cttcggtatg gtcgatgacg atcgcgccgc cggagggcag gctgacgctg cgcgaaaacg
     9301 cgctttcgat ttggtgttcg atttggaagc gggaaaacag cggcgtgtgg tcttcgtaga
     9361 gtttcagacg gcctatattg cccggcatga cgtagctcat gaactcggca acttggtcgt
     9421 aaacttcttg attgtccacc agaatttcgc cgatgtcggg gcggaaatag tcgcggatgg
     9481 cgcggatgag cagcgagctt tccataaaga gcaggtaagg gtcgtgatgc gcttttcctg
     9541 cttcttcaat cgcctgccag agttgtttga gatagttcaa atcccattcc aactcttccg
     9601 cgctgcggcc gatgccggcg gtacgggcga tgatgctcat gccgttcgga atgtcgagtt
     9661 ccgccatggc ggctttcaac tcttgacgct cttcaccttc gatacggcgg gatacgccgc
     9721 cgccgcgcgg gttgttcggc atcaatacca gatagcgtcc ggcgaggctg atgaaggtgg
     9781 tcagcgccgc gcctttgttg ccgcgctcgt ctttttcgac ttggacgatg acttccatgc
     9841 cttctttgag cacgtcttgg atgcgcgcgc gtccgccttc gtagtcttgg aagtatgagc
     9901 gggagacttc tttaaacggc aagaagccgt ggcggtcggt tccgtaatcc acgaaacacg
     9961 cttccagcga cggctcgatg cgggtaatga tgcctttgta gatattgcct ttgcgctgtt
    10021 ctttgcccag cgtttcgatg tccaaatcca gcaggttttg tccgtcgacg atggcaacgc
    10081 gcagctcttc ggcctgcgtt gcgttgaata acattctttt catgatcacc tcgtggacgg
    10141 gcggcattcg ggcgcgccgg tccggttcgg cattccgtaa ggctgggttt tccgatgttt
    10201 tcggataaaa ccggtaatca gtttttgagt tgaaaatccg cagggatgca cgttccggag
    10261 aaccgtgtgc ggaagggtcg gatacagaag gctataaaga tcgatgcggc ggtttgtctg
    10321 ccgcgttccg agcggtatgg tcggaaaaat gggtgccggc ttcttcttgt tatcgtgatg
    10381 cctgtgtttt cgggcggttt gcgtttggga cttggggccc ggctgccgtc ttacttccgc
    10441 gccgaaacgg caaaatcaat tcaaacttga ttacgttctg cgcctgccgg ctgggaacag
    10501 gcgcagggaa aatgctttgc ggagtgcgtt tttaatataa aattccgttt taaagtaaac
    10561 cgtttcagga ggcgcggcgg gcgcgctttt tgctgaaacg gatgttcgga ttatagatga
    10621 aaacgcacga aataagcaaa gattcggtca gcctgatagg ggttgccgaa cacgaggcgg
    10681 ggcaacgcct tgataactat ctgataaaaa tcctcaaggg ggttcccaag agccatatcc
    10741 accgcattat ccgcgccggc gaggtgcggt tgaacaagaa acgctgcaaa cccgacagcc
    10801 gtattgcgga gggggatacg gtgcggattc cgcctgtgcg cgtggcggag aaggaaatgc
    10861 cgtctgaaag gcgtgccgcc gtaccggcgc gtgcgtttga ggcggtgtat gaggacgacg
    10921 cgcttttggt gatcgataag ccttccggcg tggcggtgca tggcggcagc ggcgtgagtt
    10981 ttggcgttat cgaacagttg cgccgcgccc gtccggaggc gcgttatctc gaactcgtcc
    11041 accgtttgga caaggatacg agcggtttgt tgatggtggc gaagaaacgc agcgcgctcg
    11101 tcaaacttca cgaagccatc cgtaacgacc accccaaaaa aatctacctt gcgctggggg
    11161 tgggcaaact gccggacgat aatttccacg tcaggctgcc gctgtccaaa tatacgggcg
    11221 cacagggcga aaagatggtg cgcgtcagtg cggacgggca gtcggcgcat acggtgttcc
    11281 gtgtgttaag ccgtttttca gacggcattt tgcacggtgt cgggctgtcg cacctgactt
    11341 tggtgcgggc gacgttgaaa acggggcgca cgcaccaaat ccgcgtccac ctgcaatctc
    11401 aaggctgtcc gattgcgggc gacgaacgct acggcgatta tcaggcgaac cggcgtttgc
    11461 agaagttggg tttgaagcgg atgtttttgc acgcgtccga gctgcacctg aaccatccgc
    11521 tcacgggcga gccgctggtg ttaaaggtgg ggctgccgcc ggatttggca cagtttgcgg
    11581 tgatgttgga aaacgggacg aaaatgtgaa ccccgatgcc gtctgaagcc ttcagacggc
    11641 atcgggacgt gaaagtatgt ggggacagac gaatatggct gataaaaaaa gccctttgat
    11701 tgccgtcagt gtcggcgaag cgtcgggcga cctgttgggg gcgcacctga tacgcgccat
    11761 ccgcaagcgt tgtccgcagg cgcgttttgt cggtatcggc ggcgaactga tgaaggcgga
    11821 aggtttcgag agcctttatg atcaggagcg gctggcggtg cgcggctttg tcgaagtggt
    11881 caggcggctg ccggaaattt tacggatacg cagggggctg gtacgggatt tgctgtcgtt
    11941 gaaacctgat gtctttgtcg gtatcgatgc gcccgatttt aatctgggtg tggcggagcg
    12001 gctcaaacgg tcggggattc cgaccgtgca ttatgtcagt ccgtcggttt gggcgtggcg
    12061 gcgggaacgc gtgggcaaaa tcgtgcatca ggtcaaccgc gtgctgtgcc tgttcccgat
    12121 ggagccgcag ctttatcttg atgcgggcgg acgtgcggag tttgtcggtc atccgatggc
    12181 gcagcttatg cccttggaag acgaccgtga aacggcgcgg aaaactttgg gcgtggatgc
    12241 cggcatcccc gtattcgccc tgctgcccgg cagccgcgtc agcgaaatcg actatatggc
    12301 gccggtgttt tttcagacgg cattattgtt gttggaacgc tatcccgccg cacgcttcct
    12361 gctgcctgcc gcaactgagg cgacgaagcg gcgtttggcg gaagttttgc agcgtccgga
    12421 gtttgccgga ttgccgctga cggtaaccga cagacagtct gaaacagtgt gcagggcggc
    12481 ggatgcggtg ctggtaacga gcggtacggc aactttggag gtggcgttgt gtaagcgtcc
    12541 gatggtcatc agctacaaga tttcgccgct gacctatgct tatgtgaaac gcaaaatcaa
    12601 agtgccgcat gtcggcctgc cgaatatcct gttgggtaag gaggctgtgc cggaattatt
    12661 gcaatctgaa gcaaaaccgg aaaaactggc ggcggcgttg gcggactggt acgaacaccc
    12721 cgataaggtt gccgcgctgc aacaggattt cagggcgttg cacctgctgt tgaaaaaaga
    12781 tacggcggat ttggccgcgc gcgcggtttt ggaagaggcg ggatgttgag cggttaatgg
    12841 attattttcc cgaagcagca cgtattacaa aaaaaggggg agaaattgtg attaatggca
    12901 catcaaacaa taagtattta agaggaattc caaatgaaac agaactggcc cgaatgggat
    12961 taaggttaaa atataatggt cagttaactg attaattttg ttatatatga tttatgatta
    13021 tagcttatac taatacgctt acttaccttg tttcatttgt tcttcgtaaa tttctatttt
    13081 aggcaattgt gtcagttcaa tagggcaagt tgctccccac caaaaatgtt ctacataaaa
    13141 ccaaggatta tctggaaaat atagcaacat ctcttccata tccggccaaa ttcttcttaa
    13201 ttcatctacc tgtgtttttg gcgaaccagt taatattttt ggaggatttt cacgataatc
    13261 gcataattca ataacaccat ctgataaaag ttcttccaaa aaatcaaaaa atctaatttt
    13321 taaatttgga tctttgatat ccatatttaa ataattttta taaacaccaa aaataccacc
    13381 taaatattca caatattcta aaagattata ttttatcttc acattcataa cgtaaccttt
    13441 atctaaattt taattctaat ctttgcccat gtactgaatc aggttgattc ctaaactcaa
    13501 tcgtccattt tgctccagtt tgttctcggc tagttgaaaa attccttaaa ataaaggaag
    13561 agtttaaaca actgaaattt cataagagta gtagaaccaa cttggactca aaaaatctta
    13621 aactcattgt ttttgaaaag gtaaaataat atgacaactt ataccattcc aaaaaaagat
    13681 tatcaatttc tgtatatata tgagggcact ctattaaact atactttgaa aaacgatgaa
    13741 ttccatatca tcgtcaattg tgtggattat ccggatttac ctcaagaaat ccctatgcct
    13801 aattattcag actgggtaaa aattaaattc aagcagttca gctatttgaa atttgtctat
    13861 ggatacgcca caaaaaaccg agataaagat atcgataata cattggaact tggcgaatta
    13921 aagcaggatg atgaaatctt ggattatgga ggtgcgctgg aattgatagg cggtagatgt
    13981 gatcttctaa ctggttttag tatagatata gtttgccggg aaatagagtt agaattttta
    14041 gatcaggagg gtttcaatta aacgagccgt agcttgttat gccgcgcagg caactttatc
    14101 gtatttcctt ttcggttgaa accccgccac tcggacatct gtccttcggg gcggtagaat
    14161 cagattttat ttgggagggg cgtaacccct tccgaatcag ggcaacacat agggcgacgc
    14221 tttatgtgtc gtcctgtgtg ttgaaacatt gatatgccga tacggagcct gtcggcaaaa
    14281 tgccgtctga acaatatctt ttcagacggc attttgtatg ggggttaacg gttgttcagc
    14341 ccgagtacgt cctgcatatc gtacaaaccc gttttgccgt tgacccaaac tgcggcgcgg
    14401 acggcaccgg cggcaaaggt catgcggctg ctggccttgt gggtgatttc cacgcgctcg
    14461 ccgtcggtgg cgaagagggc ggtgtggtcg ccgacgatgt cgcctgcgcg gacggtggca
    14521 aagccgatgg tcgacggatc gcgcggaccg gtgtggcctt cgcggccgta aacggcgcat
    14581 tgtttgaggt ctctgccgag cgcgccggcg atgacttcgc ccatgcgtaa cgcggtgccg
    14641 ctgggggcat cgactttgtg gcggtggtgg ccttcaatga tttcgatgtc gtagccttcg
    14701 tttaatacgc gtgcgacggt gtcgaggatg tggaaggtga ggttgacgcc gacgctgaag
    14761 ttggcggcga aaacgatgcc tgtttgttcg gcggcagtgt ggatagcggc tttgcccgca
    14821 tcgtcgaagc ctgttgtgcc gatgatgatg ttgacttgtt tttcaacgca tttttgcagg
    14881 tgtttgaggg tgggctcggg gcgggtgaag tcgatgagta cgtcgctttg tgcgagaacg
    14941 gcgtcaacgt cgtctgaaat ggcgatgccg gttttgagtc cgacggcgta gcctgcgtcc
    15001 agtccgaggg cttctgagcc tgagtgttcg agcgcgccgg aaaggacggt gtcgggatgg
    15061 ttgttgacgg cttcaaccaa tacgcgtccc atacggccgt ttgcgccggc gatggcgatt
    15121 ttgagcggtg tcatgtgtgt tccttatggt ttgtctgtgt tttggcggtc tttgagggct
    15181 tcggcagcgt tttgcagggc gtcgccttcg gtgcggacga gtacgccgtt ttcaaaatag
    15241 acggtcagat tgctgcgttc tttgatgatg ccgttgcggg aggtgttgaa ggtatagtcc
    15301 cagcggtcgg tgtggaacgc gtcgcgcaac agggggctgc cgagcaggag caggacttgg
    15361 tctttggtca taccgaggcg gagtgcggcg gcggcgcggg ggtcgatttc gttgccctgt
    15421 atgactttga gcttgtatga ggggaacagc gaggcgcgtt cggcactgca cgcggcaagg
    15481 ccaaggaggg cggaaagggc gaggatgagg gttttgttca cggaaatgcc tttctgtgca
    15541 aatcgggatg ggtagtgtaa cactgcttga atattttata aaagcgaacg ataatcatac
    15601 gattaagcgg tatccgccct gtccgcgcat cggccgccgg tgcggtttta ctattgcaaa
    15661 ctgctatggt gcgatagtgg gcaaacaggc cgaaattgcg tattataacg tctattgttt
    15721 tacaggggta ttgaatatta tggaaaaatt caacaatatt gcacaactga aagacagcgg
    15781 tctgaaggtt accggcccgc gtttgaagat tttggatttg ttcgagacgc attcggaaga
    15841 gcatttgagt gcggaagatg tgtaccgcat tttgttggaa gagggtgtgg aaatcggtgt
    15901 ggcgacgatt taccgtgtgc tgacccagtt tgagcaggcg ggtattctgc aacgccatca
    15961 ttttgaaacg ggcaaggcgg tttatgagtt ggacaaaggc gaccaccatg accacatcgt
    16021 ctgcgtgaag tgcggcgagg taacggaatt ccacaatccc gaaatcgaag ccctgcaaga
    16081 caaaatcgct gaggaaaacg gctaccgcat cgtcgatcac gcgctttata tgtacggcgt
    16141 gtgcagcgac tgtcaggcca agggcaaacg ttaaatccgg acggtttgtt gttcagacgg
    16201 cattcatgat tttggatgcc gcctgtgttt ttggagaact gtcatgcgta ttccgctgct
    16261 tgcccctgac aattatgcct ttcccgatcc tgcctatgct ttggcccggt gcgacgggct
    16321 ggtcggcgtg agcggcgatt tggatgcggg gcggctgctt gaggcgtatc ggaacggcgt
    16381 gtttccgtgg ttttcccggg acgggtggtt tttttggtat gcggtcgggc cccgtgcggt
    16441 ggtgtttccc gacaggctgc atattccgcg ctcgctggcg aaaacgctgc gcaacggcag
    16501 ctatcgggtt gcggtcaacg gctgttttgc ggaagtggtc gcgcattgtg cggcagcggc
    16561 gcgcccgaat caggacggaa cttggattgc gcccgagttt cagacggcat atttgaagct
    16621 gcacgaaatg ggacacgcgc attcgttcga gtgccattat cccgatgaaa gcggtgaaac
    16681 gaggttggcg ggcggctttt acggcgtgca gatcggcagc gtgttttacg gcgaatcgat
    16741 gtttgcgttg caaccggatg cgtcgaaaat cgcgtttgcc tgcgccgtgc cgtttttggc
    16801 ggatttgggt gtggaactga tagactgcca gcaggatacg gggcatatgc gccgtttcgg
    16861 atcggaattg ctgccgtttg cggattttgc cgaacgtctg cggatgttga acgccgtgcc
    16921 gttgaaagag gaaatcgggc ggcgcgaagt ggcgtgcaag gggctttgat ggcggcttat
    16981 gcttcggtca ggttcaaata tggtggatta tagtggatta acaaaaacca gtacggtgtt
    17041 gcctcgcctt gccgtactat ttgtactgtc tgcggcttcg tcgccttgtc ctgatttttg
    17101 ttaatccact ataaaattgg aaatgacgac agccgggtaa aatcacggtg aaaaaagccg
    17161 tctgaaactt gaaaacatcg ggtttcagac ggctttttgt ttgacggttt gttgcttatt
    17221 tgagcgggcg cacttcaagt ccgaacatgc ggcgtgcagt gttcagcatt tggcagctga
    17281 agccccattc gttgtcatac catgcgaaga ctttaatcat gttgccgtca acgactttgg
    17341 tcagtgtggc gtcgaagtgg ctggcttcgg tagtgtggtt gaagtccatg gaaaccaagg
    17401 gcagggtgtt gtagcccaaa acgcctttga gcgcacccgc ttccgaggcg gctttcatca
    17461 gtgcgttgat ttcttcgact gtggtgtcgc gcgcggcttg gaagctcaaa tctaccaatg
    17521 atacgttgat ggtcggcacg cggatggcga gtccgtcgag tttgcctttc aattcgggca
    17581 gtaccagtcc gacggctttt gccgcgccag ttttggtcgg aatcatgttt tccacgccgc
    17641 tgcgggcgcg gcgcaggtct ttgtggcgca cgtcggtaac ggtttggtcg ttggtcagcg
    17701 cgtggatggt ggtcatcgcg cctttgacga tgccgacgct ttcgctcaac actttggcaa
    17761 ccggcgagag gcagttggtg gtgcaggaag cgttggaaac gacggtcatg tcggcggtca
    17821 ggatgctgtc gttcacgccg tacacgacgg ttgcatcgac atcgtcgccg cccggtgcgg
    17881 aaatgaggac ttttttcgcg ccgctttcca gatgaacttt ggctttttct ttgctggtga
    17941 acgcgccggt gcattccatg accaaatcga caccgagttc tttccacggc agttcggcag
    18001 ggttgcgggt cgagaagaag gggattttgt cgccgttgac gatgaggttg ccgccgtcgt
    18061 gggatacgtc ggcttcaaag cgtccgtgca cggtgtcgaa tttggtgagg tgggcgttgg
    18121 tttcaaggct gccgctggcg ttgacggcga cgatttggag ttggtcttga atctgataat
    18181 cgtagatggc gcgcaaaacc tggcggccga tgcgtccgta gccgttgatg gcgactttga
    18241 tgcccatggt ttgttccttt gttgaggggt tgggtagatt ttcggggcgg attatagcaa
    18301 atttgtagtg gcgtgtaatt aatattttat tgaaaacggc gcggccggaa gggtgggcgg
    18361 taagatgcgg acggcacggg tgcggcggac ggagagcttg ataaaatgcc gtctgaaacg
    18421 gttttcagac ggcatatcag ggaagggtca ggaggcggta ttctgtgcgg cttcctgttt
    18481 ggctttgtat tgtttgagat attcgagggc ggcggctttt tcgctgtcgc tgccgtattt
    18541 catatcgcgt tgggcgcggc gcaactcggc gcgttcgcgg gcttcggcta tctgtttcgc
    18601 ctgatagtct ttgcggttgt cggcggcggc gaggcggtct tgttgggttt gcgcttttgc
    18661 catggctttg gcgatgaggt cggcagggtt aaacgccggt tttttcggtg tgtcgggtgt
    18721 ttgcggacgc gcgttgcgga cggcggcttc gcgttcggca agcatggcct tgcgttcgtc
    18781 ggcttcgcgc tgtttgcgtt cgttgcgttt gaggtagcgc gcacgcgcgt gttcggcggc
    18841 ggcaaaacgg ctgtcggcgg acaggctgaa gcggcgcgcg cggggcagga cggtgtcggc
    18901 aacgggctgc atatggatgc agtcgacggg gcagggggcg acgcagagtc cgcagccggt
    18961 gcattcgtcg gcgatgacgg tgtgcataag tttgcccgca cccataatgg catcggcagg
    19021 gcaggcgcgg atgcaggcgg tgcagccgat acaggcggtt tcgtctatcc gggcgagtgc
    19081 tttggcttgg gttttggcag gtgcgacaag gggtttgccg agcagggcgg aaatgtcccg
    19141 aatgacggct tctccgcccg gggcgcagag gttgtacgct tcgcctgttg cgactgcctg
    19201 tgcgtagggc aggcagccgt cgtagccgca ttcgcggcat tgggtttggg gaagcaggcg
    19261 gtctatggcg gcggctgtgg cggtcatgtc ggtgtgcggc tcaaaatcga aagggcgtat
    19321 tttagcagaa ttgtatgccg cgcccgtttc ggatggtgcg cggtgttttg ttataatacg
    19381 gcggcgtatg ccgtttcaga cggcattttt ctgtattttc ctgttcggac ggtctatgaa
    19441 cgaattttcg cttgccccta ttgtggttgt tttgctggtg tcggtcatta cggtgatcct
    19501 gtgccgcaag ttcaacattc cctccatgct gggctacctg ctggtgggct ttttggcggg
    19561 gcccggtatg ctcagcctga ttccgaaaag ccatgcgacg gattatttgg gtgaaatcgg
    19621 gattgtgttc ctgatgttca gcattggttt ggagttctcg ctgcccaagt tgagggcgat
    19681 gaggcggctg gtattcgggc tgggcggttt gcaggtcggc gttacgatgc tgtcggtaat
    19741 gggcatactg atgctgacgg gcgtgccgtt caattgggcg tttgccgtgt cgggcgcgtt
    19801 ggcgatgtcg tccacggcga ttgtgagccg gattttgtcg gaaaagacgg aattggggca
    19861 gccgcacggt cagatggcga tgggcgtgct gctgatgcag gacatcgccg tcgtgccgct
    19921 gatgattctg attcccgcgc tggcgggcgg aggggacgga aatatttggg cggccttggg
    19981 tttggcgttt gcaaaaatgc tgctgacgct ggggctgctg tttttcgtcg gcagcaaaat
    20041 tatgtcgcga tggttcagga tggtggcaaa acgcaaatcg tccgaactct ttatgatcaa
    20101 tgtgctgctg gtaaccttgg gtgtggctta tctgactgag ctggaaggtt tgtctatggc
    20161 gttgggcgcg tttgtggcgg ggatgctgct ttcggaaacg gaataccgtt tccaagtcga
    20221 agacgacatc cgcccgttcc gcgatatttt gctcggcttt ttctttatca cggtcggcat
    20281 gaagctggac attcaggcat tgatcggcgg ctggcggcag gtattgatgc tgttggcaat
    20341 gctgctggtg ttgaaggcac tggttgtgtt tgccattgcc ttcaaaatga aacattcggt
    20401 cggcgacagc ctcaaaacgg ctttgtatct cgcgcagggc ggcgagttcg gcttcgtgat
    20461 gctggccatt gccgggcagc ttgatatggt ttcgccagaa tgggaacagg cggcgacggc
    20521 ggcggttctg ctgtcgatga ttatcgcgcc cttcctcttg ggcggcagcg atgcactggt
    20581 cgggcgtttg gtcaagtcaa gctgggacat gaagtcgctc gatctgcaca gtatgctggt
    20641 agaaaccatg agcaagtccg accatgtgct gattgtcggc ttcggcaggg gcgggcagac
    20701 ggtcggacgc gtccttgccc aagaggatat tccgtatttc gcgctcgact tggacattgc
    20761 gcgggtgcag gttgccagaa gtgcgggcga accggtgtcg ttcggcgatg cgaaacgcag
    20821 ggaagtattg gaagccgccg gtctgggacg ggcgaaaatg gtggtggtta cgctcaacaa
    20881 tatgcacgaa acgcaacacg ttttagacaa tgtgctgtcc atgtatccca atatgcccgt
    20941 atatgtgcgc gccaccaacg acgattatgt gaaaacgttt accgatatag gtgcggaaga
    21001 agccgtgtcg gacaccaaag aaaccggact cgtgctggca ggctatgcga tgttaggcaa
    21061 cggcgcgtcg tatcggcacg tctatcagac gatggcaaat atccgccaca gccgttatgc
    21121 cgcgttggag ggactgtttg tcggtagtga tgatgaggca ggattcggcg aaaccggcga
    21181 aaccgtccgc cacgcctttc ctttggctgc agaagcatac gccgtcggca aaacagtcgg
    21241 cacgcttccg atggcggctt acggcatcaa actcttgttc gtccgccgcc gcaccggccg
    21301 gattgaaaac ccggatgcct cgtttacatt ggaaggcggt gacgtgttgg tggtcgcagg
    21361 caaaaaagaa gaaattatct cttttgaaaa ctggagtttg cagggaatat aaatgaaatg
    21421 ccgaaataag gcttgcgcca tttccggtta tttggtttaa taacgatttc gcaaatcgca
//
LOCUS       DAXIDM010000027        20868 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000027 DAXIDM010000000
VERSION     DAXIDM010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 20868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20868
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.027"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(24..716)
                     /locus_tag="ACFOAE_000813"
     CDS             complement(24..716)
                     /locus_tag="ACFOAE_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFC6884334.1"
                     /translation="MFHAFIPRIHIMIKNLYKLINYAALIGFAPNIVFAWPMFVDPPA
                     SYQNIHVRSWKARRDSGIVKQDLDFSCGAASIATLLNNFYGRHYSEAEILDKMDKTQM
                     RASFDDMQRIMPELGFEAQGYALPFEQLVQLKIPVIVYLKYRKNNHFSVLNGINGETV
                     LLADPSLGHVSMSKSQFLSAWKTRDGEMEGKILAIVPKNTDFVRNQMFFNKNPVRQTR
                     FTVEQIQMRQKR"
     gene            complement(975..1577)
                     /locus_tag="ACFOAE_000814"
     CDS             complement(975..1577)
                     /locus_tag="ACFOAE_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884335.1"
                     /translation="MMQKHKCLIDFILTVASQIAYADLPLSLEELLTDKGKFKLESSI
                     SYINTERNQSEFANPIYVQTSATKIATVMAMMITPVMAQNLDSQVFDSQNVKAIQLSQ
                     AEMKETQGEFVPIIAAAAFGGALGAWGYHGANLYNHGKLGTAQGAATAAGIGAATGVA
                     ATGLAAAAGGGLAGNLAWRPGIHALGFGANAANNAVNSRK"
     gene            complement(1822..1980)
                     /locus_tag="ACFOAE_000815"
     CDS             complement(1822..1980)
                     /locus_tag="ACFOAE_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884336.1"
                     /translation="MKPPLPICTLSALAACTLSGQGGSRVYGEIKARDLCVTAPILLS
                     AFCLACSR"
     gene            complement(1977..2819)
                     /locus_tag="ACFOAE_000816"
     CDS             complement(1977..2819)
                     /locus_tag="ACFOAE_000816"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC6884337.1"
                     /translation="MLVCNPYEVVIHGTTSSGKIFRPSDWAERLCGILSSFTKDHRLS
                     YSKWVRPMLVDNIRCVAVDKKLETDNPQMFRFLMDFAADNDLRVIDCKALLEEREQGG
                     QNNPADEHVMLAQAIEEKHAAEKAQEQTASGASYVLREIGADDTATAFAALSVLRSAL
                     TDINRFTEQINKVQRPQGYRLLGIFEEGKHNAVAVCGFREACTLASGRHIHIDDIVTL
                     PQSRRKGYASRLLEEVRKIGAETGVTKIHLNVHVNHDRADAHRLYFKNGFEICAYHFR
                     CDPK"
     gene            3057..3977
                     /gene="pyrB"
                     /locus_tag="ACFOAE_000817"
     CDS             3057..3977
                     /gene="pyrB"
                     /locus_tag="ACFOAE_000817"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HFC6884338.1"
                     /translation="MPNPLYRQHIISISDLSREQLECLLQTALKLKAHPRGDLLEGKL
                     IGSCFFEPSTRTRLSFETAVQRLGGKVIGFSDGANTSAKKGETLADTARIISGYTDAI
                     IQRHPKDGAARVAAEFSRVPVINAGDGTNQHPSQTLLDLVTIYETQGRLDKLKIAMAG
                     DLKYGRTVHSLCQALKRWGCEFAFVSPPSLAMPDYITEELDEAGCRYRILGSLEEAAE
                     WADILYMTRVQRERFDEQEFAKIQGKFNLDASMLARAKPNLRVLHPLPRVDEIHPDVD
                     ATPHAYYFEQATNGVYARMAILSLVLNEEV"
     gene            3987..4445
                     /gene="pyrI"
                     /locus_tag="ACFOAE_000818"
     CDS             3987..4445
                     /gene="pyrI"
                     /locus_tag="ACFOAE_000818"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009347 - aspartate carbamoyltransferase
                     complex [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HFC6884339.1"
                     /translation="METPKLSVEAIEKGTVIDHIPAGRGLTILRQFKLLHYGNAVTVG
                     FNLPSKTQGSKDIIKIKGVCLDDKAADRLALFAPEAVVNTIDNFKVVQKRHLNLPDEI
                     AEVFRCPNTNCAGHGEPVKSRFYVKKHNGQTRLKCHYCEKTYSRDSVAEA"
     gene            4510..5175
                     /locus_tag="ACFOAE_000819"
     CDS             4510..5175
                     /locus_tag="ACFOAE_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884340.1"
                     /translation="MMMHASVQSRFAPILYVLIFFAGFLTAQIWFNQKAYTEELPPLL
                     SALSAVALVWLAWAFVSARSKAKAEKFYREKMIQNESIHPVLHASLQHLEHKPQMLAL
                     LVKNHGKGVAEQVRFKAEVLPDDEDARTIAAELAKMDMFALGTDAVASGETYGRVFAD
                     IFELSAALEGRAFKGMLKLTAEYKNIFGDACRSETALELGALNQALQEISKTSEKSKR
                     IFY"
     gene            complement(5238..6455)
                     /locus_tag="ACFOAE_000820"
     CDS             complement(5238..6455)
                     /locus_tag="ACFOAE_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFC6884341.1"
                     /translation="MQRRIITLLCAAGMAFSTQTLAANLEVRPNAPERYTVKQGDTLW
                     GISGKYLYSPWQWGRLWDANRDQIHNPDLIYPDQVLVLRHVDGEPRLGLEQTDGIPVV
                     KMSPDKEVSGYGIPAIDVNFYRIFMRHPQIVSRKETAAAPRLLSGPEGRLLYTKGTRV
                     YTKGLKEPGRYLTYRINKNITDPDTGKFLGQEVAFSGIVRSLDYTDSVLEQRSKQAGE
                     RPKDNEYHTRTHPLITPLRTPSIQPLVVETAISEIQQGDYLMKMPEDTDRFNMMPHEP
                     SRPVQAKIVSVFEGTRIAGQFQTITIDKGEADGLDKGTVLSLYKRKKTMQVDLSNNFK
                     SRDTVELISTPAEEVGLAMVYRTSEHLSSAIILENISDISVGDTAANPGRDLDNIPDQ
                     GRSRVKFGFNRSE"
     gene            6639..7142
                     /gene="def"
                     /locus_tag="ACFOAE_000821"
     CDS             6639..7142
                     /gene="def"
                     /locus_tag="ACFOAE_000821"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFC6884342.1"
                     /translation="MALLNILQYPDERLHTVAKPVEQVDERIRKLIADMFETMYESRG
                     IGLAATQVDVHERVVVMDLTEDRSEPRVFINPVIVEKDGETTYEEGCLSVPGIYDTVT
                     RAERVKVEALNEKGEKFTLEADGLLAICVQHELDHLMGIVFVERLSQLKQGRIKTKLK
                     KRQKHTI"
     gene            7229..8155
                     /gene="fmt"
                     /locus_tag="ACFOAE_000822"
     CDS             7229..8155
                     /gene="fmt"
                     /locus_tag="ACFOAE_000822"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFC6884343.1"
                     /translation="MKVIFAGTPDFAAAALKAVAAAGFEIPLVLTQPDRPKGRGMQLT
                     APPVKQAALELGLRVEQPEKLRNNAEALQMLKEVEADVMVVAAYGLILPQDVLDVPKH
                     GCLNIHASLLPRWRGAAPIQRAIEAGDAETGVCIMQMDIGLDTGDVVSEHRYAIQPTD
                     TVNEVHDALMEIGAAAVVADLQQLQSKGRLNAVKQPEEGVTYAQKLSKEEARIDWSES
                     AAVIERKIRAFNPVPAAWVEYQGKPMKIRRADVVAQQGTAGEVLSCSADGLVVACGEN
                     ALKITELQPAGGRRMNIAAFAAGRHIEAGTKL"
     gene            8234..9493
                     /gene="rsmB"
                     /locus_tag="ACFOAE_000823"
     CDS             8234..9493
                     /gene="rsmB"
                     /locus_tag="ACFOAE_000823"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFC6884344.1"
                     /translation="MSMALAQKLAADSIAAVAEGRNLQDVLAQIRTAHPDLMAQENGA
                     LQDIAYGCQRYLGSLKHMLAQMLKKPIGNPQLESLLLAALYQLHYTRNAPHAVVNEAV
                     ESIAKIGRGQYRSFANAVLRRFLRERDKLVASCKKDDVAKHNLPLWWVAYLKNHYPKH
                     WHNIAAALQSHPPMTLRVNRRHGNAESYLEKLVAEGIAAKALDEYAVTLEEAVPVNRL
                     PGFSDGIVSVQDFGAQQAAYLLNPKDGERILDACAAPGGKTGHILELADCRVTALDID
                     AGRLKRVEDNIARLGFQTASTACADAQDLSAWYDGKPFDAVLADVPCTASGVARRNPD
                     VKWLRRPTDALKTARQQEALLDALWQVLKSGGRMLIATCSVFVEENDGQLQKFLNRHA
                     DAELIESRVLLPNKHQDGFYYALIQKQ"
     gene            9459..10055
                     /locus_tag="ACFOAE_000824"
     CDS             9459..10055
                     /locus_tag="ACFOAE_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4390 domain-containing protein"
                     /protein_id="HFC6884345.1"
                     /translation="MAFITRLFKSSKWLIVPLMLPAFQNVAAEGIDVSRAEARITDGG
                     QLSISSRFQTELPDQLQQALRRGVPLNFTLSWQLSAPIIASYRFKLGQLIGDDDNIDY
                     KLSFHPLTNRYRVTVGAFSTDYDTLDAALRATGAVANWKVLNKGALSGAEAGETKAEI
                     RLTLSTSKLPKPFQINALTSQNWHLDSGWKPLNIIGNK"
     gene            10055..12175
                     /locus_tag="ACFOAE_000825"
     CDS             10055..12175
                     /locus_tag="ACFOAE_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFC6884346.1"
                     /translation="MRRFLPIAAICAVVLLYGLTAATGSTSSLADYFWWIVAFSAMLL
                     LVLSAVLARYVILLLKDRRDGVFGSQIAKRLSGMFTLVAVLPGVFLFGVSAQFINGTI
                     NSWFGNDTHEALERSLNLSKSALNLAADNALGNAVPVQIDLIGAASLPGDMGRVLEHY
                     AGSGFAQLALYNAASGKIEKSINPHKLDQPFPGKARWEKIQRAGSVRDLESIGGVLYA
                     QGWLSAGTHNGRDYALFFRQPVPKGVAEDAVLIEKARAKYAELSYSKKGLQTFFLATL
                     LIASLLSIFLALVMALYFARRFVEPVLSLAEGAKAVAQGDFSQTRPVLRNDEFGRLTK
                     LFNHMTEQLSIAKEADERNRRREEAARHYLECVLEGLTTGVVVFDEQGCLKTFNKAAE
                     QILGMPLTPLWGSSRHGWHGVSAQQSLLAEVFAAIGAAAGTDKPVHVKYAAPDDAKIL
                     LGKATVLPEDNGNGVVMVIDDITVLIHAQKEAAWGEVAKRLAHEIRNPLTPIQLSAER
                     LAWKLGGKLDEQDAQILTRSTDTIVKQVAALKEMVEAFRNYARSPSLKLENQDLNALI
                     GDVLALYEAGPCRFAAELAGEPLTVAADTTAMRQVLHNIFKNAAEAAEEADVPEVRVK
                     SETGQDGRIVLTVCDNGKGFGREMLHNAFEPYVTDKPAGTGLGLPVVKKIIEEHGGRI
                     SLSNQDAGGACVRIILPKTVKTYA"
     gene            12168..13445
                     /locus_tag="ACFOAE_000826"
     CDS             12168..13445
                     /locus_tag="ACFOAE_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HFC6884347.1"
                     /translation="MRSSDILIVDDEIGIRDLLSEILQDEGYSVALAENAEEARKLRH
                     QARPAMVLLDIWMPDCDGITLLKEWAKNGQLNMPVVMMSGHASIDTAVEATKIGAIDF
                     LEKPISLQKLLSAVENALKYGAAQTETGPVFDKLGNSAAIQEMNREVGAAVKCASPVL
                     LTGEAGSPFETVARYFHKNGTPWVSPARVEYLIDMPMELLQKAEGGVLYVGDIAQYSR
                     NIQAGIAFIVGKAEHRRVRVVASGSRAAGSDGIACEEKLAELLSESVVRIPPLRMQHE
                     DIPFLIQGIACNVAESQKIAPAAFSEEALAALTRYDWPGNFDQLQSVVATLLLEADGQ
                     EIGAAAVSSLLGQNVPAEGAEDMVGGFNFNLPLRELREEVERRYFEYHIAQEGQNMSK
                     VAQKVGLERTHLYRKLKQLGIGVSRRAGEKTEE"
     gene            13536..14723
                     /gene="dprA"
                     /locus_tag="ACFOAE_000827"
     CDS             13536..14723
                     /gene="dprA"
                     /locus_tag="ACFOAE_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFC6884348.1"
                     /translation="MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQV
                     APAVRHKQAAEAWRNAEKRASARQAAEAALEWEMRDGCRLMLLQDEDFPEMLTQGLTA
                     PPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
                     AAHQGALQAEGDTVAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFP
                     RRNRLIAALSQVTLVVEAALESGSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIK
                     DGAKLVECLDDILNECPGLLQNTGASSYSINKDTPDTGSRAVQTAYAPPPAAKMPSEG
                     AAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQR
                     IRT"
     gene            14749..15210
                     /locus_tag="ACFOAE_000828"
     CDS             14749..15210
                     /locus_tag="ACFOAE_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 family protein"
                     /protein_id="HFC6884349.1"
                     /translation="MTEVIAYLIEHFQDFDTCPPPEDLGMLLEEAGFDTMEIGNTLMM
                     MEVLLNSSEFSAEPADSGALRVYSKEETDNLPQEVMGLMQYLIEEKAVSCEQREIIIH
                     ALMHIPGDEITVDTAKVLTLLLLWANKSELPVLVGDELMSALLLDNKPTMN"
     gene            15282..17588
                     /gene="topA"
                     /locus_tag="ACFOAE_000829"
     CDS             15282..17588
                     /gene="topA"
                     /locus_tag="ACFOAE_000829"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFC6884350.1"
                     /translation="MAKNLLIVESPSKAKTLKKYLGGDFEILASYGHVRDLVPKSGAV
                     DPDNGFAMKYQLISRNSKHVDAIVAGAKEAENIYLATDPDREGEAISWHLLEILKSKR
                     GLKNIKPQRVVFHEITKNAVLDAVAHPREIEMDLVDAQQARRALDYLVGFNLSPLLWK
                     KIRRGLSAGRVQSPALRLICERENEIRAFEAQEYWTVHLDSHKGRSKFTAKLAQYNGA
                     KLEQFDLSNEAAQADVLKELEGKEAVVTAIEKKKRSRNPAAPFTTSTMQQDAVRKLGF
                     TTDRTMRTAQQLYEGIDVGQGAIGLITYMRTDSVNLADEALTEIRHYIENKIGKEYLP
                     SAAKQYKTKSKNAQEAHEAIRPTSVYRTPESVKPFLSADQFKLYQMIWQRTVACQMTP
                     AKFDQTTVDITVGKGVFRVTGQVQTFAGFLSVYEESSDDEEGEDSKKLPEMSEGDKLP
                     VDKLYGEQHFTTPPPRYNEATLVKALEEYGIGRPSTYASIISTLKDREYVTLEQKRFM
                     PTDTGDIVNKFLTEHFAQYVDYHFTAKLEDQLDEIADGKRQWIPLMDKFWKPFIKQVE
                     EKEGIERAKFTTQELDETCPKCGEHKLQIKFGKMGRFVACAGYPECSYTRNVNETAEE
                     AAERIAKAEAEQAELDGRECPKCGGRLVYKYSRTGSKFIGCTNYPKCKHVEPLEKPKD
                     TGVQCPQCKKGNLVERKSRYGKLFYSCSTYPDCNYATWNPPVAESCPKCAWPVLTIKT
                     TKRWGVEKVCPQKECGWKEQIEPPAPKE"
     gene            complement(17661..18356)
                     /locus_tag="ACFOAE_000830"
     CDS             complement(17661..18356)
                     /locus_tag="ACFOAE_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884351.1"
                     /translation="MMKDLNLSNSLFKGYNDKHGLMICGYEWGWSKADEAAYVAGEYK
                     LPENKIDHTFANKSLYFGEQAKKWRYDNTIKNWFEMWGHPLDENGLGGAFEKSLVQTN
                     WAATQGNTIDNPDKFTQPEHIDNFLYHIEKLRPKVILFMGSRLADFLNNQNVLPRFEQ
                     LVGKQTKPLETVQKEFDGTRFNVKFQSFEDCEVVCFPHPSASRGLSYDYIALFAPEMN
                     RILSDFKTTRGFK"
     gene            complement(18376..18927)
                     /locus_tag="ACFOAE_000831"
     CDS             complement(18376..18927)
                     /locus_tag="ACFOAE_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884352.1"
                     /translation="MEFLSLYPWWSFFIILTIILSYIGFCAHLHIQNRAVFFYSYRDV
                     TIIFLTPVILIALSYLIKNKEILSACILCITLIAFSWAWIITYRSNTKRFFLSLLIVW
                     GKLLLSTIVWAILAISLGLAVITGNSKRKKYERRDRHAERNEKAFIGALLVGFELSRN
                     LLNLCCLHKDFSTPSKNIEVNRS"
     gene            19045..19422
                     /locus_tag="ACFOAE_000832"
     CDS             19045..19422
                     /locus_tag="ACFOAE_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiprotein-bridging factor 1 family protein"
                     /protein_id="HFC6884353.1"
                     /translation="METHEKIRLMRELNKWSQEDMAEKLAMSAGGYAKIERGETQLNI
                     PRLEQLAQIFKIDMWDLLKSGGGGMVFQINEGDSGGDIALYASGDVSMKIEFLKMELK
                     HCKEMLEQKDKEIELLRKLTETV"
     gene            19511..20080
                     /gene="rsmD"
                     /locus_tag="ACFOAE_000833"
     CDS             19511..20080
                     /gene="rsmD"
                     /locus_tag="ACFOAE_000833"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFC6884354.1"
                     /translation="MAAGKHTKHSNRVRIIGGQCRGRKLSFTSADGLRPTPDSVREKL
                     FNWLGQDLTGKTVLDLFGGSGALGIEAASRNAKRVLISDNNRQTVQTLQKNSRELGLG
                     QVQIVCSDGIAYLKTVSEQFDVVFLDPPFAWQDWQILFDALKPCLNPRAFVYLEAGTL
                     PDIPDWLTEYREGKSGQSTFELRVFQVAE"
     gene            20203..20454
                     /locus_tag="ACFOAE_000834"
     CDS             20203..20454
                     /locus_tag="ACFOAE_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HFC6884355.1"
                     /translation="MSLFITDECINCDVCEPECPNDAISQGEEIYEINPNLCTQCVGH
                     YDEPQCQQVCPVDCILIDEEHPETHDELMAKYEKIIQFK"
     gene            20551..20634
                     /locus_tag="ACFOAE_000835"
     tRNA            20551..20634
                     /locus_tag="ACFOAE_000835"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20585..20587,aa:Tyr,seq:gta)
     gene            20665..20738
                     /locus_tag="ACFOAE_000836"
     tRNA            20665..20738
                     /locus_tag="ACFOAE_000836"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20697..20699,aa:Gly,seq:tcc)
     gene            20748..20822
                     /locus_tag="ACFOAE_000837"
     tRNA            20748..20822
                     /locus_tag="ACFOAE_000837"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20780..20782,aa:Thr,seq:ggt)
BASE COUNT         5229 a         5294 c         5698 g         4647 t
ORIGIN      
        1 ataaatgggc aaaaatcggt ttattatcgt ttttgccgca tttggatttg ttctaccgta
       61 aaacgtgttt gacgaacggg attcttatta aaaaacatct gatttctaac aaaatcagta
      121 ttttttggca cgatggctaa aatttttcct tccatttcgc catcacgtgt tttccatgcg
      181 ctcaagaatt gtgatttgct cattgagacg tgccccagcg atggatcagc cagcaaaaca
      241 gtttctccgt taataccgtt caataccgaa aaatggttgt ttttacggta ttttaaatac
      301 acaattacag gaatttttag ttgtaccaac tgttcaaatg gcaaagcata accttgtgct
      361 tcaaaaccca gttcgggcat tatgcgttgc atatcatcaa aagaagcacg catttgggtt
      421 ttatccattt tgtctaagat ttctgcttca gaataatgtc tgccataaaa attattcagt
      481 aacgtggcaa tcgaagccgc gccgcaagaa aaatccaaat cttgttttac tatgccggaa
      541 tctcgccgtg ctttccaact ccgtacatgg atgttttggt aagaagcggg ggggtcaaca
      601 aacataggcc aagcaaaaac tatatttggg gcgaaaccaa tcaaagccgc ataatttatc
      661 aatttataaa gattttttat cataatatgt atacgcggaa taaacgcatg aaacataaaa
      721 aaataaaatc atatgcaatt ttattgcatg aataaatatg aataaaatag ataatgatgg
      781 gagtaaatac gccatgtatt ttggaagttt aaatttatta ataataaaat aatttatcgt
      841 agcgcaaata aatcccaaaa ttggaacgat tagaaaaaaa attaatacac ccatcatcat
      901 gcaaactcta tattaataaa tagctaacta attctattgt ggaaattaat tagctaacta
      961 aaagttatta atgattattt tcgagaattg actgcattgt tggcagcatt ggcaccaaaa
     1021 cctagtgcat gaatacccgg tctccatgcc aaattcccag ccaatccgcc tccggcagca
     1081 gcagccagcc ctgttgccgc tactcctgtt gccgcaccga ttcctgccgc agtagccgcg
     1141 ccttgcgcag ttcctaattt accatgatta tacaaattag caccatgata cccccatgca
     1201 cctaatgcac cgccaaaagc agcggctgca ataatgggaa caaattcacc ttgtgtttct
     1261 ttcatttcag cctgtgataa ttgaattgct ttcacatttt ggctgtcaaa aacttggctg
     1321 tctaaatttt gcgccattac aggtgtaatc atcatagcca ttacagttgc aattttcgtt
     1381 gcgctggttt gcacataaat aggattagca aattcgcttt gattgcgttc agtgttgatg
     1441 tagctaatac tgctttctag tttgaattta cccttgtcag tcaataattc ttccaaactt
     1501 aaaggtaagt cagcataagc aatttggctg gcaacagtca aaataaaatc tattagacat
     1561 ttgtgttttt gcatcatttc gtttgatttt ctagtttttg agaatgatac aaagtttttt
     1621 tacaaagtaa agagtcactc tgaaaaacat tttttcatta taaatcaaaa tattgataga
     1681 ataaatagcg agcatcgatt cacggtgtac tttagtgcaa agcgtacaac gcgagcctga
     1741 accaccagcc gcaacaggaa aagaaagccg atagagtgca atgcttgcca acgtgcaagc
     1801 gagcttgcaa gaacgcttgg ctcaacgaga gcaggcaaga cagaaagcag aaagcaggat
     1861 aggagcggta acgcaaaggt ctcgggcttt gatttcgccg taaaccctgc tgccgccttg
     1921 tccggaaagg gtgcaggcgg cgagtgccga cagggtgcag atggggaggg ggggtttcat
     1981 ttggggtcgc aacggaagtg gtatgcgcag atttcaaaac cgtttttgaa atacaggcgg
     2041 tgcgcgtcgg cacggtcgtg gttgacgtgg acgttgaggt ggattttggt tacccctgtt
     2101 tccgcgccga ttttgcggac ttcttccaaa aggcgcgagg cgtagccttt gcggcggctt
     2161 tgcggcaggg taacgatgtc atcgatgtgg atgtggcggc cgctggcgag ggtgcaggct
     2221 tcgcggaagc cgcagacggc gacggcattg tgtttgcctt cttcaaaaat acccagcagg
     2281 cggtagcctt gggggcgttg gactttgttg atctgttcgg taaagcggtt gatgtcggtc
     2341 agggcggaac gcaaaacgct caaggctgca aaggcggtgg cggtgtcgtc cgcgccgatt
     2401 tcgcgcaaaa cgtaggatgc gcccgaggcg gtctgttcct gtgctttctc ggcggcgtgt
     2461 ttttcttcga ttgcctgtgc cagcatgacg tgttcgtcgg cagggttgtt ttgtccgccc
     2521 tgttcgcgtt cttcgagcag ggctttgcag tcgatgacgc gcaggtcgtt gtcggcggca
     2581 aagtccatca ggaagcggaa catttggggg ttgtcggttt ccagtttttt atcgacggcg
     2641 acgcagcgga tgttgtccac cagcatgggg cgcacccatt tcgaatagga aagcctgtgg
     2701 tctttggtga acgaggacag aatgccgcac aggcgttccg cccagtcgct gggacggaaa
     2761 atcttgccgg aactcgttgt gccgtggatg acgacttcgt aggggttgca gactaacatg
     2821 gcggcttcct gaaaagaaat gtctggcgcg attatacctt atgcttatgc gggcgtgttt
     2881 ggatatgccg tctgaaaagt acgggattcg tgcggtaaaa ctttgcggcg gcaaatgtgc
     2941 gataatacgc gccgtattgc cgcttttgcg aagctgttcc gcaaacatac gggcggcgtg
     3001 gacgacgtat aaccggatac ccgcctgacg cgggtttttt acggaagggg gcaaaaatgc
     3061 ctaatccgct ttacagacag cacatcatct cgatttcgga tttgtcgcgc gaacagttgg
     3121 aatgcctgct tcagacggca ttgaagctga aggcgcatcc gcgcggcgat ttgttggaag
     3181 gcaaacttat cggttcgtgc ttctttgaac cgtccacgcg cacgaggctg tcgtttgaaa
     3241 cggcggtgca gcggctgggc ggcaaggtca tcggcttttc ggacggcgcg aataccagtg
     3301 ccaaaaaagg cgagacgctt gccgataccg cccgcatcat ttccggctac accgacgcaa
     3361 tcatccaacg ccaccccaaa gacggcgcgg cgcgcgtggc agcggagttt tcgcgcgtcc
     3421 ccgtcatcaa cgccggcgac ggcaccaacc agcaccccag ccagaccttg ttggatctgg
     3481 taacgattta tgaaacgcag gggcgtttgg acaagctcaa aatcgccatg gcgggcgact
     3541 tgaaatacgg gcgcaccgtg cattcgcttt gtcaggcgtt gaaacgctgg ggctgcgaat
     3601 ttgcctttgt ttcgccgccc agcctcgcga tgcccgacta cattaccgaa gagttggacg
     3661 aagccggctg ccgataccgt atcctcggca gtttggaaga ggcggcggaa tgggcggaca
     3721 tcctgtatat gacccgcgtc cagcgcgaac gtttcgatga acaggaattt gccaaaatcc
     3781 aaggcaaatt caatctcgac gcatccatgc ttgcccgcgc caaaccgaac ctgcgcgtgc
     3841 tgcacccttt gccgcgcgtg gacgaaatcc atcccgatgt cgatgctacg ccgcatgcct
     3901 attatttcga gcaggcgacc aacggcgttt atgcgcgtat ggcgatattg tcgctggtgt
     3961 tgaacgaaga agtgtgagga accgatatgg aaaccccgaa actcagtgtc gaagccattg
     4021 aaaaaggtac ggttatcgac catattcccg ccggcagggg gctgaccatc ctgcgccagt
     4081 tcaaactttt gcactacggc aacgcggtaa ccgtgggctt caacctgccc agcaaaaccc
     4141 aaggcagcaa agacatcatc aaaatcaaag gcgtgtgctt ggacgacaaa gccgccgacc
     4201 gcctcgccct gttcgccccc gaagcggtgg tcaataccat cgacaatttc aaggtcgtgc
     4261 agaagcggca tttgaacctg cccgatgaaa ttgccgaagt gttccgttgc ccgaacacga
     4321 attgcgccgg ccacggcgag ccggtcaaaa gccggtttta tgttaaaaaa cacaacgggc
     4381 agacgcggct gaaatgccat tactgcgaaa aaacctacag ccgggattcg gtggcggaag
     4441 cctgacggat tcccttaaac cgagcgggcg gcatttcgtc tgccgcttgt tttgccaatc
     4501 tgaaatggaa tgatgatgca cgcttctgtc caaagccgtt tcgcaccgat actttatgtt
     4561 ttgattttct ttgccggttt tttgaccgcg caaatctggt tcaatcagaa agcctatact
     4621 gaagagctgc ctccgcttct gtccgcattg tccgccgtcg cgctggtgtg gctggcgtgg
     4681 gcgttcgtgt cggcgcgttc aaaggctaag gcggaaaagt tctaccgcga aaaaatgata
     4741 cagaacgaaa gcatacaccc cgtcctgcac gcttctttgc aacacttgga acacaagccg
     4801 caaatgctcg ccctgctggt caaaaaccac ggcaaagggg tggcggaaca ggtcaggttc
     4861 aaggcggaag tgctgcccga cgacgaagac gcgcgcacga ttgccgccga gttggcaaaa
     4921 atggatatgt tcgcattggg gacggacgcg gtcgcctcgg gcgaaaccta cgggcgcgtg
     4981 ttcgccgata ttttcgagtt gtcggcggct ttggaagggc gcgcgttcaa aggaatgttg
     5041 aaactgacgg cggaatataa aaacatcttc ggcgatgcct gccgttcgga aacggcgttg
     5101 gagttgggcg cgctcaatca ggcgttgcag gagatttcaa aaacatcgga aaagtccaaa
     5161 cggatatttt attgaagatg gaaaaatgcc gtctgaaacg gaaggtgttt cagacggcat
     5221 ttttgtcgga tgattaatta ttcggagcgg ttgaagccaa acttcacgcg gctgcggccc
     5281 tgatccggta tattgtccaa atcgcgtccc ggattggcgg cggtgtcgcc tacggaaata
     5341 tcggagatgt tttccaaaat gatggcggac gacaggtgtt cggaggtgcg gtaaaccatt
     5401 gccaagccca cttcttcggc aggagtggaa atcagctcga cggtatccct gcttttgaaa
     5461 ttgttggaga ggtcgacctg catcgttttc ttgcgtttgt agaggctcaa aaccgtgcct
     5521 ttgtccaaac cgtccgcctc gcctttgtcg atggtgatgg tttgaaactg gccggcaatc
     5581 cttgtacctt caaacacgga aacgatttta gcctgaaccg ggcgggacgg ttcgtgcggc
     5641 atcatgttga agcggtcggt gtcttccggc attttcatca ggtagtcgcc ctgctgtatt
     5701 tcggaaatgg cggtttcgac caccagcggc tgtatcgaag gggtgcgcag cggggtaatc
     5761 aaaggatggg tgcgggtatg gtattcgttg tctttcggcc gttctccagc ctgtttcgag
     5821 cgttgttcga ggacagagtc ggtatagtcg agggagcgca cgatgccgct gaatgcgact
     5881 tcctgcccga ggaatttacc cgtatccgga tcggtgatgt ttttattgat tcggtaggtc
     5941 aggtagcggc ccggctcttt caggcctttg gtgtaaaccc tggtgccttt ggtgtacagc
     6001 agcctgcctt ccgggcccga gagcaggcgc ggcgcggcag cggtttcttt gcgggaaacg
     6061 atttgcgggt gccgcataaa gatgcggtag aagttgacat cgatggcggg aataccgtat
     6121 ccggacactt ccttatccgg actcattttg acgacgggga tgccgtctgt ctgttccaag
     6181 ccgaggcgcg gttcgccgtc aacgtggcgc aacaccaata cctggtccgg ataaatcagg
     6241 tcgggattgt ggatttgatc ccggttcgcg tcccacaggc ggccccattg ccacgggctg
     6301 tacaggtatt tgcccgaaat gccccacagg gtgtcgccct gtttgaccgt gtagcgttcc
     6361 ggcgcgttcg ggcgcacctc caaatttgcc gccaaagttt gtgttgagaa tgccatacct
     6421 gccgcgcaga gcagggttat aatacgacgt tgcataaccg ttccccttat ctgataaatt
     6481 tcggtttgtc ttgcttgatt gggttggaaa aagcggcggc agcccctcgg gatgtgccgc
     6541 gtgataaaaa atgttccgca ttttaacatc gaattatccg caccatcacg gtaattatga
     6601 aaaacaggcg gcgtatccgc cgaaggaaag agaaaattat ggctttattg aatatcttgc
     6661 aatatcccga cgagcgtctg cacacggtgg caaagcctgt cgaacaagtc gacgagcgca
     6721 tccggaagct gattgccgat atgtttgaaa cgatgtacga atcgcgcggc atcgggctgg
     6781 cggcgacgca ggtcgatgtg cacgagcgcg tggtcgtgat ggatttgacc gaagaccgca
     6841 gcgaaccgcg cgtgttcatc aaccccgtca tcgttgaaaa agacggcgaa accacttacg
     6901 aagagggctg cctgtccgtg ccgggcattt acgacaccgt aacccgcgcc gaacgcgtca
     6961 aggtcgaggc tttgaacgaa aaaggcgaaa agttcacgct ggaggcggac ggcttgctgg
     7021 cgatttgcgt gcagcacgag ttggaccacc tgatgggcat cgtgtttgtc gaacgcctgt
     7081 cgcagctcaa gcagggacgc atcaaaacca agctgaaaaa acgtcagaaa catacgattt
     7141 gacccttttg ccgtgccgtc tgaacgctgc aaagttttca gacggcacgg tcttgtccga
     7201 caattttacg cacacgcagg aacacgctat gaaagtcatc ttcgccggca cgcccgattt
     7261 tgccgccgcc gccttaaaag ccgttgccgc cgccggtttt gaaatcccgc tggtgctgac
     7321 ccagcccgac cgtccgaaag ggcgcggtat gcaactgact gccccgcccg tcaaacaagc
     7381 cgcgctggaa ctcggtttgc gcgtcgaaca gcccgaaaag ctgcgcaaca acgccgaagc
     7441 cctgcaaatg ctcaaagagg tcgaggcaga cgtaatggtg gttgccgcct acggtttgat
     7501 tctgccgcaa gacgtgttgg atgtgccgaa acacggctgc ctcaatatcc acgcctcgct
     7561 gctgccccgt tggcgcggcg cggcgccgat tcagcgcgcg attgaggcag gcgatgccga
     7621 aaccggcgtg tgcattatgc agatggacat cggtttggac accggcgatg tggtcagcga
     7681 acaccgctac gccatccaac cgaccgatac cgtcaacgaa gtccacgacg cgctgatgga
     7741 aatcggtgcg gcggcggttg ttgccgattt gcaacagctt caaagcaaag gccgtctgaa
     7801 cgcggtcaaa cagcccgaag aaggcgtaac ttacgcccaa aaactaagca aagaagaggc
     7861 gcgtatcgat tggagcgaaa gtgcggcggt tatcgaacgc aaaatccgcg ccttcaaccc
     7921 cgtgcctgcc gcgtgggttg agtatcaggg caagccgatg aaaatccggc gggcggacgt
     7981 ggtggcgcaa caaggcacgg caggcgaagt gttgtcctgt tcggcggacg gtttggtcgt
     8041 tgcctgcggc gaaaacgcgc tgaagattac cgaattgcag cctgccggcg gcaggcgtat
     8101 gaatatcgcg gcgtttgcag caggacggca tatcgaagca gggacgaagc tgtaaatccc
     8161 ttcagacggc attccgatcc gcaaacggga atgccgtctg aaaccatcag tcgaagaaag
     8221 cgaatcacat aatatgagta tggcacttgc ccaaaaactt gccgccgaca gcattgcggc
     8281 ggttgccgaa ggacgtaacc ttcaggacgt gttggcgcaa atccgcaccg cgcatcccga
     8341 ccttatggcg caggaaaacg gcgcgttgca ggacatcgcc tacggctgcc agcgttattt
     8401 gggcagtttg aaacatatgc tcgcgcagat gctgaaaaag ccgattggca atccgcagct
     8461 cgaaagcctg cttttggcgg cgttgtacca gctgcattac acgcgcaacg cgccccacgc
     8521 cgtggtcaat gaggcggtgg aaagcatcgc gaaaatcgga cgcgggcagt accgttcgtt
     8581 tgccaacgcg gttttgcgcc gctttttgcg cgaacgcgac aagcttgtgg cttcctgtaa
     8641 aaaagacgat gtagcgaaac acaacctgcc gctgtggtgg gtggcttact tgaaaaacca
     8701 ttatccgaaa cactggcaca acatcgccgc cgcgctgcaa tcccatccgc cgatgacttt
     8761 gcgcgtcaac cgccgacacg gcaatgccga aagctatttg gaaaaactgg tggcggaagg
     8821 tatcgcggct aaggcgttgg acgaatatgc ggttacgttg gaagaagccg tgccggtgaa
     8881 ccgcctgcct ggtttttcag acggcattgt ttcggtacag gacttcggcg cgcagcaggc
     8941 ggcgtatttg ttaaacccga aagacggcga acggattttg gacgcgtgcg ccgcgccggg
     9001 cggcaagacg gggcatatct tggaactggc ggattgccgt gttaccgcct tggacattga
     9061 tgcaggccgt ctgaaacggg tggaagacaa tatcgcgcgt ctgggctttc agacggcatc
     9121 gacggcgtgt gccgatgcac aggacctgtc ggcatggtat gatgggaaac cgtttgatgc
     9181 cgtccttgcc gacgtgccgt gtaccgcctc gggcgtggcg cggcgcaatc ccgacgtgaa
     9241 atggctacgc cgtccgaccg acgcgctcaa aaccgcccgc cagcaggaag ccctgctaga
     9301 tgcattgtgg caggtgctga aaagcggggg aaggatgttg atcgctacct gttccgtgtt
     9361 cgtcgaggaa aacgacggac aattgcaaaa attcctcaac cgccatgccg atgcagaact
     9421 gatcgaatcg cgggtactct taccgaacaa acaccaagat ggcttttatt acgcgcttat
     9481 tcaaaagcag taaatggctg attgtgccgc tgatgctccc cgcctttcag aatgtggcgg
     9541 cggaggggat agatgtgagc cgtgccgaag cgaggataac cgacggcggg cagctttcca
     9601 tcagcagccg cttccaaacc gagctgcccg accagctcca acaggcgttg cgccggggcg
     9661 tgccgctcaa ctttacctta agctggcagc tttccgcccc gataatcgct tcttatcggt
     9721 ttaaattggg gcaactgatt ggcgatgacg acaatattga ctacaaactg agtttccatc
     9781 cgctgaccaa ccgctaccgc gttaccgtcg gcgcgttttc gacagactac gacaccttgg
     9841 atgcggcatt gcgcgcgacc ggcgcggttg ccaactggaa agtcctgaac aaaggcgcgc
     9901 tgtccggtgc ggaagcaggg gaaaccaagg cggaaatccg cctgacgctg tccacttcaa
     9961 aactgcccaa gccttttcaa atcaatgcat tgacttctca aaactggcat ttggattcgg
    10021 gttggaaacc tctaaacatc atcgggaaca aataatgcgc cgttttctac cgatcgcagc
    10081 catatgcgcc gtcgtcctgt tgtacggact gacggcggca accggcagca ccagttcgct
    10141 ggcggattat ttctggtgga ttgttgcgtt cagcgcaatg ctgctgctgg tgttgtccgc
    10201 cgttttggca cgttatgtca tattgctgtt gaaagacagg cgcgacggcg tattcggttc
    10261 gcagattgcc aaacgccttt ctgggatgtt tacgctggtt gccgtactgc ccggcgtgtt
    10321 tctgttcggc gtttccgcac agttcatcaa cggcacgatt aattcgtggt tcggcaacga
    10381 tacccacgag gcgcttgaac gcagcctcaa tttgagcaag tccgcattga atttggcggc
    10441 agacaacgcc ctcggcaacg ccgtccccgt gcagatagac ctcatcggcg cggcttccct
    10501 gcccggggat atgggcaggg tgctggaaca ttacgccggc agcggttttg cccagcttgc
    10561 cctgtacaat gccgcaagcg gcaaaatcga aaaaagcatc aacccgcaca agctcgatca
    10621 gccgtttcca ggtaaggcgc gttgggaaaa aatccaacgg gcgggttcgg tcagggattt
    10681 ggaaagcata ggcggcgtat tgtacgcgca gggctggctg tcggcgggta cgcacaacgg
    10741 gcgcgattac gccttgtttt tccgtcagcc ggttcccaaa ggcgtggcag aggatgccgt
    10801 cttaatcgaa aaggcaaggg cgaaatatgc tgagttgagt tacagcaaaa aaggtttgca
    10861 gacctttttc ctggcaaccc tgctgattgc ctcgctgctg tcgatttttc ttgcactggt
    10921 catggcactg tatttcgccc gccgtttcgt cgaacccgtc ctatcgcttg ccgagggggc
    10981 gaaggcggtg gcgcaaggcg atttcagcca gacgcgcccc gtgttgcgca acgacgagtt
    11041 cggacgcttg accaagttgt tcaaccacat gaccgagcag ctttccatcg ccaaagaagc
    11101 agacgagcgc aaccgccggc gcgaggaagc cgccaggcat tatcttgaat gcgtgttgga
    11161 ggggctgacc acgggcgtgg tggtgtttga cgaacaaggc tgtctgaaaa ccttcaacaa
    11221 agcggcggaa cagattttgg ggatgccgct tacccccctg tggggcagca gccggcacgg
    11281 ttggcacggc gtttcggcgc agcagtccct gcttgccgaa gtgtttgccg ccatcggcgc
    11341 ggcggcaggt acggacaaac cggtccatgt gaaatatgcc gcgccggacg atgccaaaat
    11401 cctgctgggc aaggcaaccg tcctgcccga agacaacggc aacggcgtgg taatggtgat
    11461 tgacgacatc accgttttga tacacgcgca aaaagaagcc gcgtggggcg aagtggcgaa
    11521 gcggctggca cacgaaatcc gcaatccgct cacgcccatc cagctttccg ccgaacggct
    11581 ggcgtggaaa ttgggcggga agctggatga gcaggatgcg caaatcctga cgcgttcgac
    11641 cgacaccatc gtcaaacagg tggcggcatt gaaggaaatg gtcgaagcat tccgcaatta
    11701 tgcgcgttcc ccttcgctca aattggaaaa tcaggatttg aacgccttaa tcggcgatgt
    11761 gttggcattg tatgaagccg gtccgtgccg gtttgcggcg gagcttgccg gcgaaccgct
    11821 gacggtggcg gcggatacga ccgccatgcg gcaggtgctg cacaatattt tcaaaaatgc
    11881 cgccgaagcg gcggaagaag ccgatgtgcc cgaagtcagg gtaaaatcgg aaacagggca
    11941 ggacggtcgg attgtcctga cggtttgcga caacggcaaa gggttcggca gggaaatgct
    12001 gcacaacgcc ttcgagccgt atgtaacgga caaaccggcg ggaacgggat tgggtctgcc
    12061 tgtggtgaaa aaaatcattg aagaacacgg cggccgcatc agcctgagca atcaggatgc
    12121 gggtggcgcg tgtgtcagaa tcatcttgcc aaaaacggta aaaacttatg cgtagcagcg
    12181 atattttaat tgtagacgac gaaatcggca tccgcgacct gctgtcggaa atcctgcagg
    12241 acgaaggtta ttcggtcgca ttggcggaaa acgccgaaga ggcgcgcaag ctgcgccatc
    12301 aggcgcgccc cgcgatggtg ctgctggata tttggatgcc tgattgcgac ggcatcaccc
    12361 ttttgaagga gtgggcgaaa aacgggcagc tcaatatgcc ggtggtgatg atgagcgggc
    12421 atgccagcat cgataccgcc gtggaagcca ccaaaatcgg cgcgatcgat tttttggaaa
    12481 aaccgatttc cctgcaaaag ctgctgtctg ccgtcgaaaa cgcgttgaag tacggtgcgg
    12541 cgcaaaccga aacggggcct gtattcgaca agctgggcaa cagtgcggcg attcaggaaa
    12601 tgaaccgtga ggtaggggct gcggtgaaat gtgcctctcc cgtacttttg acgggcgagg
    12661 cgggttcgcc gtttgaaacg gtggcacgct atttccataa aaacggtacg ccgtgggtca
    12721 gcccggcaag ggtcgaatat ctgatcgata tgccgatgga actgttgcag aaggcggagg
    12781 gcggcgtttt gtatgtcggc gacatcgccc agtacagccg caacatccaa gccggtattg
    12841 cctttattgt cggaaaggcg gaacaccgcc gcgtcagggt ggtcgcatcg ggcagcaggg
    12901 cggcaggttc agacggcatt gcctgcgagg aaaagctggc ggaactgctg tcggagtcgg
    12961 tcgtccgcat tccgccgctg cgtatgcagc atgaagatat tcccttcctg atacagggga
    13021 ttgcctgcaa tgtggcggaa agtcaaaaga ttgcgcccgc cgcattcagt gaagaggcac
    13081 ttgccgcatt gacccgttac gactggccgg gaaatttcga ccaactgcaa agcgtcgttg
    13141 caacgctgtt gttggaggcg gacggacagg aaatcggcgc ggcggcggtt tcttcccttt
    13201 tggggcagaa tgtgcctgcc gagggagcgg aagatatggt gggcgggttt aatttcaacc
    13261 tgcccctgcg cgaattgagg gaggaggtgg agcggcgtta tttcgagtac cacatcgccc
    13321 aagaaggtca gaatatgagc aaagtggcgc agaaggtcgg tttggaacgc acgcaccttt
    13381 accgcaaact caaacagctc ggcatcggcg tttcgcgccg ggcgggggaa aaaaccgaag
    13441 aataggcccg gacggtcggt tttccggctg cgggcttttg ttttcagacg gcatttggtg
    13501 caaatgccgt ctgaaatcgt aaggggacgg attttatgac agaggacgaa cgtttcgcgt
    13561 ggctgcaatt ggcgtttacg ccctatatcg gcgcggaaag cttcctgctg ctgctgcgcc
    13621 gtttcggcag cgcgtcaaac gccctgtccg caccggcgga acaggtcgcc ccggcggtgc
    13681 ggcacaagca ggcggccgag gcttggcgca atgcggaaaa acgcgcctcg gcgcggcagg
    13741 cggcagaagc ggcgttggaa tgggaaatgc gggacggatg ccgcctgatg ctgcttcagg
    13801 atgaagattt ccccgaaatg ctgacgcagg ggctgaccgc gccgccggtt ttgtttttgc
    13861 gcggcaacgt gcggctgctg cacaagcctt ccgccgccat cgtcggcagc cgccatgcca
    13921 cgccgcaggc aatgcggatt gccaaagatt tcggcagggc gttgggagag aaaggcattc
    13981 ccgttgtgtc gggtatggct tcgggcatcg acaccgccgc ccatcagggc gcgttgcagg
    14041 cggaaggcga caccgtcgcc gtgtggggga cgggtataga ccgcatttat ccgccgtcca
    14101 acaaaaacct tgcctatgaa atcgccgaaa aaggattgat tgtcagcgag ttccccatcg
    14161 gtacgcggcc gtatgccggc aattttccgc gccgcaaccg cctgattgcc gccctgtcgc
    14221 aagtaacgct ggtggttgaa gccgccttgg aatccggttc gctgattacc gccggcttgg
    14281 cggcagaaat ggggcgcgaa gtgatggcgg tacccggttc gatagacaac ccccacagca
    14341 aaggctgcca caaactgatt aaagacggcg cgaaattggt ggaatgcctg gacgacatcc
    14401 tgaacgaatg cccggggcta ttgcaaaata cgggtgcttc atcatattct ataaataagg
    14461 atacgcccga cacgggcagt cgcgccgttc agacggcata cgccccgccg cctgccgcaa
    14521 aaatgccgtc tgaaggggcg gcaggcggca cagccgtcgg cggcatactg gataaaatgg
    14581 gtttcgaccc catccatccc gacgtgcttg ccggacagtt ggctatgcct gccgcagatt
    14641 tgtatgccgc actgttggaa ttggaattgg acggcagcgt tgccgcaatg cccggcggca
    14701 gataccagcg tatccgaact tgaacgcact ttatattaag gaacacgaat gaccgaagtc
    14761 atcgcctacc tcatcgaaca tttccaagat ttcgatacct gtccgccgcc cgaagacttg
    14821 ggtatgctgc ttgaagaagc gggtttcgat acgatggaaa tcggcaacac cctgatgatg
    14881 atggaagtat tgctcaacag ctccgaattt tccgccgaac ctgccgacag cggcgcattg
    14941 cgcgtgtaca gcaaagaaga aaccgacaac ctgccgcagg aagtgatggg gctgatgcag
    15001 tatctgattg aagaaaaagc cgtcagctgc gaacagcggg aaatcatcat ccacgcgctc
    15061 atgcacattc cgggcgacga aattaccgta gataccgcca aagtgctgac cctgctgctt
    15121 ttatgggcaa acaagagcga gctgcccgtg ttggtcggcg acgagctgat gagcgcgctt
    15181 ttactcgaca acaaacccac gatgaactga agcggcttca gacggcccgc ccgaggccgt
    15241 ctgaaacgtc ggcatcaaaa ccaccatcca gagaacgaca aatggcgaaa aacctattaa
    15301 tcgtcgaatc cccgtccaaa gccaaaaccc tgaaaaaata tttgggcggc gattttgaaa
    15361 tccttgcatc ctacggacac gtccgcgacc tcgtccccaa aagcggcgcg gtcgatcccg
    15421 acaacggctt tgcgatgaaa taccaattga ttagccgcaa cagcaaacac gtcgatgcca
    15481 tcgttgccgg tgccaaagaa gctgaaaaca tctacctcgc caccgacccg gatagggaag
    15541 gcgaagccat ttcctggcat cttttggaaa tcctcaaatc caaacgcggc ttgaaaaaca
    15601 tcaagccgca gcgtgtcgtg ttccacgaaa tcaccaaaaa cgccgtgctc gatgccgttg
    15661 cccatccgcg cgaaatcgaa atggacttgg tcgatgcaca acaagcccgc cgtgctttgg
    15721 actatttggt cggctttaac ctttcgccat tgttatggaa aaaaatccgc cgaggtttga
    15781 gcgcggggcg tgtgcaaagc cctgctttgc gcctgatttg tgagcgcgaa aacgaaatcc
    15841 gcgcgtttga agcgcaggaa tattggacgg tgcatctcga cagccacaaa ggccgcagca
    15901 agttcaccgc caaactcgcc caatacaacg gcgcgaaact cgaacaattc gacctgtcga
    15961 acgaagccgc gcaagccgac gtattgaaag aactcgaagg caaagaagcc gtcgttaccg
    16021 ccattgaaaa gaaaaagcgc agccgcaatc ctgccgcgcc gttcaccact tctaccatgc
    16081 agcaggatgc cgtgcgcaaa ctcggcttca ccaccgaccg caccatgcgt accgcccaac
    16141 agctttatga aggtatagac gtagggcagg gcgcgatcgg tctgattacc tatatgcgta
    16201 ccgacagcgt gaatttggcg gatgaagcgt taaccgaaat ccgccattac attgaaaaca
    16261 aaatcggcaa agaatatctg ccgagtgccg ccaaacaata caaaaccaaa tccaaaaacg
    16321 cccaagaagc ccacgaagcc atccgtccga cttccgtgta ccgcacgccc gaaagcgtca
    16381 aacccttcct gagcgcagac cagttcaaac tctatcaaat gatttggcag cgtaccgtcg
    16441 cctgtcagat gacgcctgcc aaattcgacc aaaccaccgt cgatattacc gtcggcaaag
    16501 gcgtattccg cgtaaccgga caagtgcaaa ccttcgcagg cttcttgagc gtttatgaag
    16561 aaagcagcga cgatgaagaa ggcgaagaca gcaaaaaact gcccgaaatg agcgaaggcg
    16621 ataaattgcc cgtggacaaa ctctacggcg aacaacactt taccactccg ccgccgcgct
    16681 acaacgaagc cacgctggtt aaagccctcg aagaatacgg catcggccgc ccctcgacct
    16741 acgccagcat catctccacg ctcaaagacc gcgaatacgt tacccttgag caaaaacgct
    16801 tcatgcccac cgacacaggc gacatcgtca acaaattcct gaccgaacac ttcgcccaat
    16861 acgtcgatta ccacttcacc gccaaactcg aagaccagct tgacgaaatt gccgacggca
    16921 aacgccaatg gattcccttg atggacaaat tctggaaacc gttcatcaaa caagtggaag
    16981 aaaaagaagg catcgaacgc gccaaattta ccacgcagga acttgatgaa acctgcccga
    17041 aatgcggcga acacaaactg caaatcaaat tcggcaaaat gggtcgtttt gttgcgtgtg
    17101 ccggttatcc cgagtgcagc tacacgcgca acgtcaacga aactgccgaa gaagccgccg
    17161 agcgcatcgc caaagccgag gctgaacaag ccgaactcga cggacgcgaa tgtcctaaat
    17221 gtggtggtcg cctagtgtac aaatacagcc gaaccggcag caaattcatc ggctgcacca
    17281 actaccccaa atgcaaacac gtcgagccgc tggaaaaacc gaaagatacc ggcgtccagt
    17341 gtccgcaatg caaaaaaggc aacctcgtcg agcgcaaatc ccgctacggc aaactgtttt
    17401 acagttgcag cacctatccc gactgtaact acgccacatg gaacccaccc gttgcagaaa
    17461 gctgtccaaa atgcgcatgg ccggttttga ccatcaaaac caccaaacgc tggggtgtag
    17521 aaaaagtctg cccacaaaaa gaatgcggct ggaaagaaca gattgaaccg cccgcgccga
    17581 aggagtaaga ttaggttggt ttgaaagaga aaaggtcgtc tgaaaaattt tcagacgacc
    17641 tttgcttttc tgtgattggt ttatttgaat ccgcgtgttg ttttaaagtc cgataaaatc
    17701 cggttcattt caggcgcaaa caaggcgatg taatcgtaag atagaccgcg actggcactg
    17761 ggatggggaa agcagacgac ttcgcaatct tcaaacgatt ggaatttgac attgaaacgt
    17821 gtaccgtcaa attctttttg caccgtctcc agcggtttgg tctgcttacc gaccaactgc
    17881 tcgaagcgtg gcagtacatt ttggttgttc agaaaatccg ccaacctgct gcccatgaag
    17941 aggatgactt tcggacgcag tttttcgatg tggtagagaa aattatcgat gtgctcgggt
    18001 tgtgtgaact tgtctggatt gtcgatagtg ttgccctgtg tagcagccca gttggtttga
    18061 accagggatt tttcaaatgc accgcccaat ccattttcgt ctaaggggtg tccccacatt
    18121 tcaaaccaat tttttatcgt attatcgtaa cgccactttt ttgcctgctc tccgaaatag
    18181 agggatttgt ttgcaaatgt atggtcgatt ttgttttcag ggagtttgta ttcacctgct
    18241 acataagcag cctcatcggc tttactccaa ccccattcat acccacaaat cattaaacca
    18301 tgtttgtcgt tgtagccttt gaacagactg ttgctcaaat tcaaatcctt catcatgaac
    18361 tcttcctttt aaaatttaag agcgattgac ttcaatgttt ttagatgggg tggaaaaatc
    18421 cttgtgtagg caacataaat tcaataaatt tcttgataat tcgaaaccta ctaatagcgc
    18481 acctataaaa gctttttcat tacgttcagc atgacggtca cgtcgttcat attttttacg
    18541 cttgctgttc cctgttatta cagctaagcc aagtgatatg gcgagaattg cccaaacaat
    18601 agtacttaat aacaattttc cccatactat caataaggaa agaaaaaacc ttttagtatt
    18661 agatcgatag gttataatcc atgcccatga aaatgcaata agagttatac ataagataca
    18721 agctgacagg atttctttat ttttaattaa ataacttaga gcgatgagga tgacaggtgt
    18781 caagaaaata atagttacat cccgatagct ataaaagaaa actgccctat tttgaatgtg
    18841 gagatgtgca cagaatccaa tatagctaag gataatagtt aatataataa aaaaagacca
    18901 ccaagggtaa agagatagga attccatgtt ttcctttttt tgtaaaaagg aaaaaatttt
    18961 atctaagagt taattgccta accagccaga agaagtttaa aatctatccc aataattcaa
    19021 ccatctatac agaaagttca gcttatggaa acccacgaaa aaatccgcct gatgcgcgaa
    19081 ttgaataaat ggtcccagga ggatatggcg gaaaagctgg cgatgtcggc aggcgggtat
    19141 gccaaaatcg aacggggcga aacgcagtta aatatcccgc gtttggagca gttggctcag
    19201 attttcaaaa tcgatatgtg ggacttgctc aaatcgggcg gtggtgggat ggtgtttcag
    19261 attaatgaag gtgatagtgg tggcgatatt gcgttgtatg cgtcgggtga tgtttcgatg
    19321 aaaatagaat ttttaaaaat ggagttgaaa cactgcaaag aaatgttgga acaaaaagac
    19381 aaagaaatcg agctgctccg caagctgacc gaaaccgttt aaacagatat gccgtctgaa
    19441 aaaagttttc agacggcata ttctttgaca ggtcttgtat aataccgttt gaacttacag
    19501 gtttttgatt atggcggcag gcaaacatac caaacacagc aaccgggtac gcattatcgg
    19561 cgggcaatgc cggggcagga aattgagttt cacatccgcc gacggactgc gtccgacacc
    19621 cgacagcgtg cgtgaaaagc tgtttaactg gctgggacag gatttgacgg gtaaaacggt
    19681 tttggatctc ttcggaggca gcggcgcact cggtatagaa gccgcttcgc gcaacgccaa
    19741 acgcgtgctg atttcggata acaaccgcca aaccgtgcag accttgcaga aaaacagtcg
    19801 cgaactgggt ttggggcagg tgcaaatcgt ctgttcagac ggcatcgcat atttgaagac
    19861 cgtatccgaa cagtttgatg ttgtctttct cgacccgccg tttgcatggc aggactggca
    19921 aatcctgttc gatgccttga agccgtgcct gaacccccgg gcattcgtct atctcgaggc
    19981 gggtacgctg ccggatattc ccgattggct gacggaatat agagaaggga aatcagggca
    20041 gagtacattt gaattaaggg ttttccaagt ggctgaataa tatgcgcttt gataatcatt
    20101 tccgagttgt aaacattcgt ttgcaaccgt ccggttcaaa aaaaccttgt gctataatcc
    20161 gcgcccgccc ggttttgata atttagtgga aaaggaaaag aaatgtcgct ttttattacc
    20221 gacgagtgca tcaactgcga cgtatgcgaa cccgaatgcc ccaatgatgc catttcccaa
    20281 ggcgaggaaa tttacgaaat caaccccaac ctctgcacgc agtgcgtcgg acactacgat
    20341 gagccgcagt gccagcaggt ttgcccggtg gactgcatcc tgattgacga agaacatccc
    20401 gaaacccatg acgagttgat ggcgaaatac gaaaagatta tccagtttaa ataaattctt
    20461 tttaaaacat caaattatgt ctgttttgaa ataaaatcaa aaaaaaactt gacggaaaag
    20521 caagccgcta ataaactaac gttctctttt ggagggattc ccgagcggtc aaagggggca
    20581 gactgtaaat ctgttgcgaa agcttcgaag gttcgaatcc ttctccctcc accaaaattc
    20641 ttacttgggg cagtagcgag taatgcgggt gtagctcaat ggtagagcag aagccttcca
    20701 agcttacggt gagggttcga ttcccttcac ccgctccaaa caattaggcc catgtagctc
    20761 aggggtagag cactcccttg gtaagggaga ggtcggcagt tcaaatctgc ccatgggcac
    20821 catctctcga ttattcattt ctttaaggct tagatatata ggatattg
//
LOCUS       DAXIDM010000028        20223 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000028 DAXIDM010000000
VERSION     DAXIDM010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 20223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20223
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.028"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(533..1675)
                     /locus_tag="ACFOAE_000838"
     CDS             complement(533..1675)
                     /locus_tag="ACFOAE_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFC6884356.1"
                     /translation="MKKSVLAVLAALSLAACGGSEKNAVQPQADAASVANAEAAATDT
                     LNIYNWSNYVDESTVEDFKKANNLKLTYDLYENNETLEAKMLTGKSGYDLVVPGIAFL
                     PRQIEAGAYQKVNKDLIPNYKNIDPELLKMLETADPGNQYAVPYFSGVNTIAITAKGK
                     ELLGGKLPENGWDLLFKPEYTHKLKSCGIALWDTPSEMFPILLNYLGKDPKGSNPEDL
                     KAAAEVLKSIRPDVKRFSPSIIDELARGDICLAAGNGGDLNLAKARSEEVKNNVGIEV
                     LNPKGMGFWIESWLIPADAKNVANAHKYINYTLDPEIAAKNGIAVTFAPASKPAREKM
                     PAELVNTRSIFPNEQDMKDGFVMPQMSTDAKKLSVSLWQKIKVGTN"
     gene            1979..2242
                     /gene="rpsT"
                     /locus_tag="ACFOAE_000839"
     CDS             1979..2242
                     /gene="rpsT"
                     /locus_tag="ACFOAE_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFC6884357.1"
                     /translation="MANSAQARKRARQSVKQRAHNASLRTAFRTAVKKVLKAVEAGDK
                     AAAQAVYQESVKVIDRIADKGVFHKNKAARHKSRLSAKVKALA"
     gene            2402..3550
                     /locus_tag="ACFOAE_000840"
     CDS             2402..3550
                     /locus_tag="ACFOAE_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HFC6884358.1"
                     /translation="MPTMGAEMNTRNMRYILLTGLLPMASAFGETALQCAALTDNVTR
                     LACYDRIFAAQLPSSAGQEGQESKAVLNLTETVRSSLDKGEAVIVVEKGGDALPADSA
                     GETADIYTPLSLMYDLDKNDLRGLLGVREHNPMYLMPLWYNNSPNYAPGSPTRGTTVQ
                     EKFGQQKRAETKLQVSFKSKIAEDLFKTRADLWFGYTQRSDWQIYNQGRKSAPFRNTD
                     YKPEIFLTQPVKADLPFGGRLRMLGAGFVHQSNGQSRPESRSWNRIYAMAGMEWGKLT
                     VIPRVWVRAFDQSGDKNDNPDIADYMGYGDVKLQYRLNDRQNVYSVLRYNPKTGYGAI
                     EAAYTFPIKGKLKGVVRGFHGYGESLIDYNHKQNGIGIGLMFNDLDGI"
     gene            3693..4394
                     /locus_tag="ACFOAE_000841"
     CDS             3693..4394
                     /locus_tag="ACFOAE_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF502 domain-containing protein"
                     /protein_id="HFC6884359.1"
                     /translation="MTEPAAEGGKAAKALKKYLITGILVWLPIAVTVWVVSYIVSASD
                     QLVNLLPKQWRPQYVLGFNIPGLGVIVAIAVLFVTGLFAANVLGRQILAAWDSLLGRI
                     PVVKSIYSSVKKVSESLLSDSSRSFKTPVLVPFPQSGILTIAFVSGQVSNAVKAALPQ
                     DGDYLSVYVPTTPNPTGGYYIMVKKSDVRELDMSVDEALKYVISLGMVIPDDLPVKTL
                     AGPMPSEKADLPEQQ"
     gene            4452..6260
                     /gene="aspS"
                     /locus_tag="ACFOAE_000842"
     CDS             4452..6260
                     /gene="aspS"
                     /locus_tag="ACFOAE_000842"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFC6884360.1"
                     /translation="MRTNYCGLISEQYLDQTVTVKGWVHRRRDHGGVIFIDLRDREGI
                     VQVVIDPDTPEAFAAADSSRNEYVLSITGRVRNRPEGTTNDKMISGKIEILAKEIEVL
                     NAAATPPFQIDDENISENVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFID
                     IETPMLTRSTPEGARDYLVPSRVHPGEFFALPQSPQLFKQLLMVAGFDRYYQITKCFR
                     DEDLRADRQPEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALGVDLGDFPRMPYSEA
                     MFYYGSDKPDMRINLKFTELTDLMKTEEFKVFRGAADMKGGRVVALRVPNGAKFSRKE
                     IDEYTKFVGIYGAKGLAYIKVNDVGNLSNGEDSGLQSPIVKFLSENALKEIIARTGAE
                     NGDIIFFGADKAKVVNEAIGALRIKVGLEHGAENGYFTDEWKPLWVVDFPMFEYDEEA
                     DRYVAVHHPFTAPKEGHEDLMVSDPANCLARAYDMVLNGWEIGGGSIRIHRADVQEKV
                     FAALKISPEEQQEKFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKT
                     QRAQCLLTNAPNSVDDKQLRELSLRLRQKVAETKEA"
     gene            6411..6695
                     /locus_tag="ACFOAE_000843"
     CDS             6411..6695
                     /locus_tag="ACFOAE_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFC6884361.1"
                     /translation="MKKLLLAAVVSLSAATAFAGDSAERQIYGDPHFEQNRTKAVKML
                     EQRGYQVHDVDADDHWGKPVLEVEAYKDGREYDIVLSYPDLKIIKEQLDR"
     gene            6862..8754
                     /gene="speA"
                     /locus_tag="ACFOAE_000844"
     CDS             6862..8754
                     /gene="speA"
                     /locus_tag="ACFOAE_000844"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008792 - arginine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HFC6884362.1"
                     /translation="MPILTIREVCNINHWGIGYYDVDDSGEIIVRPNPAQHNQTASLQ
                     KLTEAVQQKHQARLPVLFCFPQILEHRLRDINRAFQTAREECGYKGGYCLVYPIKVNQ
                     HRRVIESLMSSGQPHGLEAGSKAELMAVLAHAGTRQTLIVCNGYKDREYIRFALMGEK
                     LGHQVYLVIEKLSEIQMVLEEAEKLGIKPRLGVRARLASQGSGKWQSSGGEKSKFGLS
                     ASQVLQLVDILKQKNRLDCLQLLHFHLGSQLGNIRDVATGVHESARFYVELHKLGVNI
                     RCFDVGGGLGVDYEGNRTQSDCSVNYSLNEYAATVVWGISQACLEHGLPHPTIITESG
                     RGITAHHAVLVANVIGVERYKPRRLDAPSPEAPRVLHSMWETWTDISASREKRSLRSW
                     IHEGQFDLADVHNQYNVGLLSLAQRAWAEQLYLNICHEVGELFNEKHRSHRTIIDELQ
                     ERFADKLYVNFSLFQSLPDAWGIDQLFPVCPITGLNEPIARRAVLLDITCDSDGTIDR
                     YIDGDGIAGTMPMPDYPEEEPPLLGFFMVGAYQEILGNMHNLFGDTATADVVVGEDGQ
                     FTVIDYDEGNTVADMLEYVYQDPKELMKRYREQIEHSDLPASQAMSFLKELEAGLNGY
                     TYLEDE"
     gene            8853..9776
                     /gene="speB"
                     /locus_tag="ACFOAE_000845"
     CDS             8853..9776
                     /gene="speB"
                     /locus_tag="ACFOAE_000845"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008783 - agmatinase activity [Evidence
                     IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HFC6884363.1"
                     /translation="MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESQADWVITGVPY
                     DMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRD
                     FVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNG
                     SEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKI
                     KETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVE
                     VAPSYDQSDITALAGATIALEMLYLQGAKKD"
     gene            9974..11440
                     /locus_tag="ACFOAE_000846"
     CDS             9974..11440
                     /locus_tag="ACFOAE_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008509 - monoatomic anion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006820 - monoatomic anion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HFC6884364.1"
                     /translation="MMKLGFKPIPLAIAAVLCALVLALPVPDGVKPQAWTLLAMFVGV
                     IAAIIGKAMPLGALSIIAVGLVAVTGVTADKPGAAMSDALSAFANPLIWLIAIAVMIS
                     RGLLKTGLGMRIGYLFIAVFGRKTLGIGYSLALSELLLAPVTPSNTARGGGIIHPIMQ
                     SIAGSYGSNPAKGTEGKMGKYLALVNYHSNPISSAMFITATAPNPLIVNLIAENLGSS
                     FRLSWGAWAWAMAVPGVIAFFVMPLILYFLYPPEIKETPNAVQFAKDRLREMGKMSAD
                     EIIMAVIFGILLLLWADVPALITGNHAFSINATATAFIGLSLLLLSGVLTWDDVLKEK
                     SAWDTIIWFGALIMMAAFLNKLGLIKWFSGVLAESVGGLGVSGTAAGVILVLAYMYAH
                     YMFASTTAHITAMFGAFLAAAVSLNAPAMPTALMMAAASNIMMTLTHYATGTSPVIFG
                     SGYTTMGEWWKAGFIMSVVNFLIFFVIGSIWWKVLGYW"
     gene            complement(11647..12723)
                     /locus_tag="ACFOAE_000847"
     CDS             complement(11647..12723)
                     /locus_tag="ACFOAE_000847"
                     /EC_number="2.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0071972 - peptidoglycan L,D-transpeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0018104 - peptidoglycan-protein
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HFC6884365.1"
                     /translation="MICRKPIGHTPYFDMNKTICRTAALLISGFSYANTVIPDVSPVA
                     QGQHVFINIPQQRLFLYTDGKLTKVYPVAVGRAMTQTNLGEHKIGAKAYNPVWYIPKS
                     IQKERGDGVKTIAAGPDNPLGPVFVRLGDPKLGLGIHGTNAPASVPGVRSHGCIRMKS
                     PDALEFAKTIASGSPASVIYQMAGLNEDADRNLWLAAFRDPYGKNNLDIASLKKSIAQ
                     WAKTQGKTIAPEKVDAVLKDRTGSAVCLTCGKNGKMKMPLKSLAWIQGSSSYSQAEVI
                     EQTEETNSAEISETRTPEVPDVHTPEAQPHLNTQSDGTPTAYTEPAADSSPQVETPDQ
                     AASEPVDVLFSIDVIRQGNLRLGN"
     gene            12787..12924
                     /locus_tag="ACFOAE_000848"
     CDS             12787..12924
                     /locus_tag="ACFOAE_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase"
                     /protein_id="HFC6884366.1"
                     /translation="MATETNVAEISALDYEGRGVAKVGGKTVFIKRALLDCLMLGWFR
                     L"
     gene            12946..14088
                     /gene="bioF"
                     /locus_tag="ACFOAE_000849"
     CDS             12946..14088
                     /gene="bioF"
                     /locus_tag="ACFOAE_000849"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HFC6884367.1"
                     /translation="MKVFKQQLEQLGAQNQYRSIPDLIHQGRYITRENCKMLNMSSND
                     YLGLASDENLRRSFLQQYGGNFPSFTSSSSRLLTGNFPIYTDLEELVAQRFQRESALL
                     FNSGYHANLGILPALTTTKSLILADKFVHASMIDGIRLSRCAFSRYRHNDYEHLKNLL
                     EKNVGKFDRTFIVTESVFSMDGDVADLKQLVQLKKQFPNTYLYVDEAHAIGVYGQNGL
                     GIAERDNLIAEIDLLVGTFGKALASVGAYAVCNQVLKECLINQMRPLIFSTALPPFNV
                     AWTYFIFERLPQFSKERSHLEQLSAFLRREVAHRTQIMPSQTCIVPYILGGNEAALAK
                     AEYLQRQGYYCLPIRPPTVPKNTSRIRLSLTADMTTDEVRQFAVCL"
     gene            14098..14745
                     /locus_tag="ACFOAE_000850"
     CDS             14098..14745
                     /locus_tag="ACFOAE_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl esterase BioG family
                     protein"
                     /protein_id="HFC6884368.1"
                     /translation="MKTKFYNHQGGHLILYFAGWGTPPDAVNHLILPENHDLLICYDY
                     QDLNLDFDFSAYRHIRLVAWSMGVWAAERALQGIRLKSATAVNGTGLPCDDNFGIPCT
                     VFKGTLENLTENTRLKFERRMCGDKASFEDYQQFPARPFGEIHQELIALFAMIGQDRR
                     TDLIRWTNALVGSGDKIFMPANQHRYWTPRCTVREIDVGHYLFSRFTHWSALWNH"
     gene            14733..15515
                     /gene="bioC"
                     /locus_tag="ACFOAE_000851"
     CDS             14733..15515
                     /gene="bioC"
                     /locus_tag="ACFOAE_000851"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010340 - carboxyl-O-methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HFC6884369.1"
                     /translation="MESLTAINKSRIRQAFQKALNDYDRHALIQQKMTINLMTHLQDY
                     LPDMPLENVLELGCGSGMLSALLQKQISANYWLFNDLCDVQPQLAEKLPQSFDFYCGD
                     AENFPFQRQFDLIASASAVQWFHQPDAFIAHCKTGLKANGLLAVATFGKDNLKEVRQI
                     TNIGLNYPTLSQWQTWLAKDFELLWCEDFKVILDFDTPLDVLKHLKYTGVTATNQKNW
                     TRKNLNEFIGDYLSAFSMPSGKVHLTYHPLFFIARYSAAGRQ"
     gene            15735..17171
                     /locus_tag="ACFOAE_000852"
     CDS             15735..17171
                     /locus_tag="ACFOAE_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC6884370.1"
                     /translation="MENSLIIGLALAVLLMLLVMRAKQGKKTPKRKSQGVGNTQGQTP
                     GSNDSDWVDQIGQSVSDGTQPDWSWNESAETASAAVSAQEVDPLTEYQVYKQFGYQGK
                     AAESLAAYLDGIPDGEAKPENLIRELLDINLEVGDVDVLADNLQKYGKLIPSELLAKY
                     IEQALQRDSNHLRIRVLAEEGLGWGTQEIEKRAEGGSATAASASPPPDAGGKAYEAEE
                     IKRIPIVRGKKDVSGISQEEIGAIAGLVRADQGAKILKDKVSYETASKQYDRAIQTSE
                     KPANLIIDALKLDYQHADIDRFAGHLWKLYQTLGNYGRQVKERMLGWGYSLGYHEVFD
                     DLEKGPNDRQIKDIGMGHGYLPKNIQKFKSQHRDLVLQDSSLINTGSSPADDAVKEVE
                     SLLMYGQIEAAMDVLEQAVLKYPDESQLYITLIDIYERTEDWDRLGQFLRVLRERADR
                     LPEEVVMLMSRLLQRMNQNIKKIKRYGK"
     gene            17174..18271
                     /locus_tag="ACFOAE_000853"
     CDS             17174..18271
                     /locus_tag="ACFOAE_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC6884371.1"
                     /translation="MEVQLPKIKTVRVMLAGMTAQQESVFKMAFKMHNTTRYETVSPS
                     DGSAVPDLVLADTDAEGGFELWKELAERYKDIPVAVCSEKVPDSEVPYLPKPIRFETL
                     FPMLRKLLQGENVYGKSFIAPADRSAKNNGNVQRTVTIRQFNPNKGLLGALRFAEKNR
                     QDIAILHGNKPVLIVFPSIQRVLLTESVQKLEELCKDENLQVSCKTVPDNPQWREKAK
                     VGIMSCMWQFSIWTVQGRLIYPISPDTPFTLKSWPNLTRLANVPGSIRLSAFLTKASV
                     NLNVLYKVMPLNLNDILNYLAATYTTGFLSVDLKTVSQQAYSDMADKINIGADSASDS
                     EMMKKAEKITTSSQSQSRGLLQRLMKKLLGS"
     gene            18283..18819
                     /locus_tag="ACFOAE_000854"
     CDS             18283..18819
                     /locus_tag="ACFOAE_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HFC6884372.1"
                     /translation="MRENKIIFTGPVGVGKTTAIAAISDEALVQTDASASDMTLDRKR
                     NTTVAMDYGAISLDEDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLLDNARTNPLKD
                     LEFFLHSFRGLLEKAPVVVGITKMDIRSQPGIDVYHKYLAKHNLNVPVFEIDARKEDD
                     VKQLVSAMLFSIDPGLEV"
     gene            18821..19465
                     /locus_tag="ACFOAE_000855"
     CDS             18821..19465
                     /locus_tag="ACFOAE_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFC6884373.1"
                     /translation="MESTLSLQANLYPRLTPAGAFYAVSSDAPSAGKTLLHSLLKADA
                     DEMVSSEKLLTWADTADIDTALNLLYRLQKLEFLYGDENGHSDGINLSDEQLPLLMEQ
                     LSGSGKALLVDRNGLYLANANFHHEAAEELGLLAAEVAQMEKKYRLLIKNNLYINNNA
                     WGVCDPSGQSELTFFPLYIGSTKFILVIGGIPDLGKEAFVTLVRILYRRYSNRV"
     gene            19488..19847
                     /locus_tag="ACFOAE_000856"
     CDS             19488..19847
                     /locus_tag="ACFOAE_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="HFC6884374.1"
                     /translation="MQQLLISILEDLNNTSTDIIASAVISTDGLPMATMLPSHLNSDR
                     VGAISATLLALGSRSVQELACGELEQVMIKGKSGYILLSQAGKDAVLVLVAKETGRLG
                     LILLDAKRAARHIAEAI"
     gene            19940..20015
                     /locus_tag="ACFOAE_000857"
     tRNA            19940..20015
                     /locus_tag="ACFOAE_000857"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19973..19975,aa:Asn,seq:gtt)
BASE COUNT         5098 a         4695 c         5235 g         5195 t
ORIGIN      
        1 cgtgggaatg acgggatgca ggttttcgtg cggacgcgtt cggattcacg actgcgcggg
       61 aatgacggga tttcagtttg cggattgatt tgaagttgca aaatcccaac ggatcggatt
      121 accgctttcg cgtttcaaag ttatggcgtt atcggaaaaa cagaaaatca aagctgcaag
      181 aatttattta aaacaaccga atttcaacgg atcggattct cgcctgtagg gaatgacggc
      241 ggaaggtttt ttgtcttttc tgacagatgt ccgcaatctg aaatcctgac cgtgggaacg
      301 acggtatagt ggattaacaa aaaccagtac ggcgttgcct cgctttagct caaagagaac
      361 gattctctaa ggtgctgaag caccaagtga atcggtttcg tactatttgt actgtctgcg
      421 gctttgtcgc cttgttctga tttttgttaa tccactatat aaatatttct atttcaatcc
      481 aatataaaat gccgtccgaa cgatgttcgg acggcatttt taatgcttca aatcagttgg
      541 tgccgacttt gattttctgc cacaggctga cagacagttt tttcgcatcc gtactcattt
      601 gcggcatcac gaaaccgtct ttcatatcct gctcgttcgg gaagatggaa cgggtgttca
      661 ccagctcggc aggcattttt tcgcgcgccg gtttgctggc gggggcgaag gttacggcga
      721 tgccgttttt cgccgcgatt tcggggtcga gcgtgtagtt gatgtatttg tgggcattgg
      781 cgacgttttt cgcatcggcg ggaatcagcc aagactcaat ccagaagccc atgcctttcg
      841 gattcagcac ttcgatgccg acgttgtttt tcacttcttc ggaacgtgct ttcgccaagt
      901 tcaaatcgcc gccgttgcct gccgccaggc agatgtcgcc gcgcgccagc tcgtcgatga
      961 tggacgggct gaaacgtttg acatccggac ggatagactt caacacttcc gccgctgcct
     1021 tcaaatcttc aggattcgaa cctttggggt ctttgcccaa gtagttcagc aaaatcggga
     1081 acatttcgct cggggtgtcc cacagggcga tgccgcagga tttcagcttg tgggtgtatt
     1141 cgggtttgaa cagcaaatcc cagccgtttt cgggcagctt gccgcctaaa agctctttgc
     1201 ctttcgccgt aatcgcaatc gtgttcacgc cggagaaata ggggacggca tactggttgc
     1261 ccgggtcggc ggtttccagc attttcaaga gttcgggatc gatgttttta tagttgggaa
     1321 tcaggtcttt gttgactttt tgatacgcgc ccgcctcgat ttggcgcggc aggaaggcga
     1381 tgcccggcac aaccaaatcg taaccggatt tgccggtcag cattttggct tccagcgttt
     1441 cattgttttc gtacaagtcg taagtgagct tcagattgtt ggctttttta aagtcttcga
     1501 ccgtactctc gtcaacatag ttcgaccagt tgtagatgtt cagagtatcg gtggcagcgg
     1561 cttcggcatt ggcaacagac gcagcgtctg cttgaggttg cacggcgttt ttttcgctgc
     1621 cgccgcaggc tgccagagac agcgcggcca aaacggctaa tacggatttt ttcatacggg
     1681 cagattcctg atgaaagagg ttggaaaaaa aagaaaaccc cgcgccccat aaacaccccg
     1741 gcgcaaggtt tgggcattgt aaagtaaatt tgtgcaaact caaagtgata ttggactgat
     1801 ttccctaaaa aattaccctg ttttcaaaag agggggaaaa cgtccgcccg attttgccgt
     1861 ttttttgcgc tgtcagggtg tccgacgggc ggatagagag aaaaggcttg catataatgt
     1921 aaaccccctt taaaattgcg cgtttacaga atttattttt cttctaggag attccaatat
     1981 ggcaaacagc gcacaagcac gcaaacgtgc ccgccagtcc gtcaaacaac gcgcccacaa
     2041 cgctagcctg cgtaccgcat tccgcactgc agtgaaaaaa gtattgaaag cagtcgaagc
     2101 aggcgataaa gctgccgcac aagcggttta ccaagagtcc gtcaaagtca tcgaccgcat
     2161 cgccgacaag ggcgtgttcc acaaaaacaa agcggcacgc cacaaaagcc gtctgtctgc
     2221 aaaagtaaaa gcactggctt gatttttgca aaaccgccaa ggcggttgat acgcgataag
     2281 cggaaaaccc tgaagcccga cggtttcggg gttttctgta ttgcgggggc aaaatcccga
     2341 aatggcggaa agggtgcggt ttttatccga atccgctata aaatgccgtt tgaaaaccaa
     2401 tatgccgaca atgggggcgg agatgaatac acggaatatg cgctatattc ttttgacagg
     2461 actgttgccg atggcatccg cttttggaga gaccgcgctg caatgcgccg ctttgacgga
     2521 caatgttacg cgtttggcgt gttacgacag gatttttgcg gcacagcttc cgtcttcggc
     2581 agggcaggaa gggcaggagt cgaaagccgt actcaatctg acggaaaccg tccgcagcag
     2641 cctggataag ggcgaggcgg tcattgttgt tgaaaaaggc ggggatgcgc ttcctgccga
     2701 cagtgcgggc gaaaccgccg acatctatac gcctttgagc ctgatgtacg acttggacaa
     2761 aaacgatttg cgcgggctgt tgggcgtacg cgaacacaat ccgatgtacc ttatgccgct
     2821 ctggtacaac aattcgccca actatgcccc gggttcgccg acgcgcggta cgactgtaca
     2881 ggaaaaattc ggacagcaga aacgtgcgga aaccaaattg caggtttcgt tcaaaagcaa
     2941 aattgccgaa gatttgttta aaacccgcgc ggatctgtgg ttcggctaca cccaaagatc
     3001 cgattggcag atttacaacc aaggcaggaa atccgcgccg ttccgcaata cggattacaa
     3061 acctgaaatt ttcctgaccc agcctgtgaa ggcagatttg ccgttcggcg gcaggctgcg
     3121 tatgctcggt gcgggttttg tccaccagtc caacggacag agccgtcccg aatcgcgttc
     3181 gtggaacagg atttacgcca tggcaggcat ggaatggggc aaattgacgg tgattccgcg
     3241 cgtgtgggtg cgtgcgttcg atcagagcgg cgataaaaac gacaatcccg atattgccga
     3301 ctatatgggg tatggcgacg tgaagctgca gtaccgcctg aacgacaggc agaatgtgta
     3361 ttccgtattg cgctacaacc ccaaaacggg ctacggcgcg attgaagccg cctacacgtt
     3421 tccgattaag ggcaaactca aaggcgtggt acgcggattc cacggttacg gcgagagcct
     3481 gatcgactac aaccacaagc agaacggtat cggtatcggg ttgatgttca acgacttgga
     3541 cggcatctga accgcgtgtt cagacggtat atcaagttgc cgtgccgtct gaagccgccg
     3601 gcggtttggc ggggcgggat aaaaatttcg tttgaatccg ggcaaacgcg tataatgtgc
     3661 ggtttgtacg gactttgtcg gaatcaagca agatgacgga acctgcggcc gaaggcggta
     3721 aagctgccaa ggcgttaaaa aaatatctga ttacgggcat tttggtctgg ctgccgattg
     3781 cggtaacggt ttgggtggtt tcctatatcg tttccgcgtc cgatcagctc gtcaacctgc
     3841 tgccgaagca atggcggccg caatatgttt tggggtttaa tatcccgggg ctgggcgtta
     3901 tcgttgccat tgccgtattg tttgtaaccg gattatttgc cgcaaacgta ttgggccggc
     3961 agattcttgc cgcgtgggac agcttgttgg ggcggattcc ggttgtgaag tccatctatt
     4021 cgagtgtgaa aaaagtatcc gaatcgttgc tgtccgacag cagccgttcg tttaaaacac
     4081 cagtactcgt gccgtttccc caatcgggta ttttgacaat cgcattcgtg tccggtcagg
     4141 tgtcgaatgc ggttaaggcc gcattgccgc aggatggcga ttatctttcc gtgtatgttc
     4201 cgaccacgcc gaatccgacc ggcggttact atattatggt aaagaaaagc gatgtgcgcg
     4261 aactcgatat gagcgtggac gaagcattga aatatgtgat ttcgctgggt atggtcatcc
     4321 ctgacgacct gcccgtcaaa acattggcag gacctatgcc gtctgaaaag gcggatttgc
     4381 ccgaacaaca ataaagccgc cgttcagacg gcattttctg ttttcagttt aaatcaataa
     4441 aaggtgattt tatgcgtacc aactattgcg gtctgattag cgagcaatac ttagaccaaa
     4501 ccgttaccgt caaaggctgg gtacaccgtc gacgcgacca tggcggtgtg atttttatcg
     4561 acctgcgcga ccgcgaaggc atcgtccaag tcgtgatcga tcccgacacg cccgaagcgt
     4621 ttgccgctgc cgattcctcc cgcaacgaat acgttttgag cattaccggc cgcgtacgca
     4681 accgtcccga aggtacgacc aacgacaaaa tgatttccgg caaaatcgaa atccttgcca
     4741 aagaaatcga agtgttgaac gctgccgcta cgccgccgtt ccaaatcgac gacgaaaaca
     4801 tcagcgaaaa cgtgcgcctg accaaccgcg ttatcgactt gcgtcgtccg gtaatgcagc
     4861 gcaacctgcg cctgcgttac caagttgcta tgggcgttcg ccgctacttg gacgcgcaag
     4921 gtttcatcga cattgaaacc ccgatgctga cccgctccac gcccgaaggc gcgcgcgact
     4981 acctcgtgcc gagccgcgtt catccgggcg agttcttcgc gctgccgcaa tcgccgcaat
     5041 tgttcaaaca actgttgatg gtggcgggtt tcgaccgtta ctaccaaatc accaagtgct
     5101 tccgcgacga agacttgcgt gccgaccgtc agcctgaatt cacgcaaatc gacttggaaa
     5161 cctcgttctt aaacgaggat gaaatcatgg acatcaccga aggtatggcg aaacaagtct
     5221 tcaaagacgc gctgggcgtg gacttgggcg acttcccacg catgccttac tctgaagcca
     5281 tgttctacta cggctctgac aaaccggaca tgcgtatcaa cttgaaattc accgagttga
     5341 ccgacctgat gaaaacggaa gaattcaaag tcttccgtgg cgcagccgac atgaaaggcg
     5401 gccgcgtggt tgccctgcgt gtgccgaacg gtgcgaaatt cagccgcaaa gaaatcgacg
     5461 aatacactaa atttgtcggc atctacggtg cgaaaggtct ggcatacatc aaagtaaacg
     5521 atgtgggcaa cctttccaac ggcgaagaca gcggcctgca atccccgatt gtgaaattcc
     5581 tgtccgaaaa cgccctgaag gaaatcattg cgcgtaccgg cgcggaaaac ggcgacatca
     5641 tcttcttcgg tgcggacaaa gccaaagtcg tgaacgaagc catcggcgca ttgcgtatca
     5701 aagtcggctt ggaacacggc gcggaaaacg gctatttcac agacgaatgg aaacctttgt
     5761 gggttgtcga cttcccaatg tttgaatacg acgaagaagc cgaccgctac gttgccgtac
     5821 accatccgtt taccgcacca aaagaaggcc atgaagacct gatggtttcc gacccggcaa
     5881 attgtttggc gcgcgcctac gatatggtat tgaacggctg ggaaatcggc ggcggctcta
     5941 tccgtatcca ccgcgcagac gtgcaagaga aagtgtttgc cgcgctgaaa atcagccctg
     6001 aagagcaaca agagaaattc ggcttcctct tggacaacct gaaattcggt gcgcctcctc
     6061 acggcggcct tgcattcggc ctcgaccgtc tggtaacgct gatgaccgga gccgaatcca
     6121 tccgcgacgt gattgccttc ccgaaaacac aacgcgcaca atgcctgctg accaacgcgc
     6181 ccaacagcgt ggacgacaag cagttgcgtg aattgagcct gcgcctgcgc caaaaggtgg
     6241 ctgaaaccaa agaagcataa ggaaaacaga gccgtttgac ggctctgttt ttttcagacg
     6301 gcatttacgc ttcttgactt ccctctaatt caaacctaat tttgctgtgt tttaatggcg
     6361 gtattgaaaa acacatcttg ttcaatcaac cgataaaaaa aggactgaaa atgaaaaaac
     6421 tgttattggc cgccgttgtt tccctgagtg ccgcaaccgc atttgccggc gattctgccg
     6481 agcgtcagat ttacggcgat ccccattttg aacaaaaccg cacaaaagcc gtgaaaatgt
     6541 tggaacagcg tggttatcag gttcacgatg tcgatgccga cgaccattgg ggtaagcctg
     6601 tgctggaagt ggaagcctat aaagacggcc gcgaatacga catcgtgttg tcttaccccg
     6661 acctgaaaat catcaaagag cagctcgatc gctgactcct ttgatggcaa gctgaaccaa
     6721 aatgccgtct gaagcgttca gacggcattt tgcctgttcc tcatcaggta tgaggcaggc
     6781 ttttcttatt aaaaaaatga catttcacgc tgatttgtta taatcattcc ttttcaacac
     6841 gacagacgga gcaggtttat tatgcctatc cttaccatcc gtgaagtgtg caacattaat
     6901 cattggggca taggttatta tgatgttgac gattccggcg aaatcatcgt ccgccccaat
     6961 ccggcgcaac acaatcaaac tgcttcactg caaaaactga ctgaagccgt gcaacaaaaa
     7021 catcaggcgc gcctgcctgt tttgttttgt tttccgcaaa tcctcgaaca ccgcctccgc
     7081 gacattaacc gcgcctttca gacggcacgg gaagagtgcg gctataaggg cggttattgt
     7141 ttggtttacc ctatcaaggt caaccaacac cgccgcgtca tcgaatcgct tatgtcaagc
     7201 ggacaaccgc atggtttgga agctggttct aaagccgaac tgatggcggt tttggcacac
     7261 gccggcaccc ggcaaacatt aatcgtctgc aacggctata aagaccgtga atatatccgt
     7321 ttcgccttga tgggcgaaaa actggggcat caggtttatt tggtgattga gaagctgtcc
     7381 gaaatacaaa tggtattgga agaggcggaa aaactcggca tcaagccccg tttgggtgtg
     7441 cgcgccagac tggcttccca aggttcggga aaatggcagt cttcgggtgg ggaaaaatca
     7501 aaattcggct tgtcggcttc ccaagttttg caactggtcg atattttgaa acaaaaaaac
     7561 aggctggatt gcctgcagct tttgcatttc catttgggct cgcagcttgg gaacatccgt
     7621 gatgttgcca caggtgtaca cgaatcggct cggttttatg ttgagttgca caaactgggg
     7681 gtaaatatcc gctgttttga tgtaggcggc gggcttggcg tggattacga aggaaaccgc
     7741 acacaatcgg attgttccgt taattacagc ctcaacgaat atgccgccac agtcgtatgg
     7801 ggcatcagtc aggcttgtct cgaacacggg ctgccgcatc cgacaatcat caccgagagc
     7861 gggcgcggca ttaccgcaca tcacgccgtt ttggttgcta atgttatagg cgttgagcgt
     7921 tacaaaccgc gccggctgga tgcgccatcg cccgaagcgc cgcgtgtgtt gcacagtatg
     7981 tgggaaactt ggacggatat ttccgcctcg cgggaaaaac gttccttacg cagctggata
     8041 cacgaagggc agtttgatct tgccgatgtg cataatcagt ataatgtcgg gctgttgagt
     8101 ttggcgcaac gtgcgtgggc ggagcaactg tatttaaata tctgtcatga agtcggcgaa
     8161 ttgtttaatg aaaaacaccg gtctcaccga accattattg acgaattgca agaacgtttt
     8221 gccgataagc tgtatgtcaa tttctcactc ttccaatctt tgcccgatgc ttggggcata
     8281 gatcaacttt tccctgtttg tcccattacc ggtttgaatg aaccgattgc gcgccgcgcc
     8341 gtgttgttgg acattacctg cgattcagac ggtacgattg accgctacat cgacggcgac
     8401 ggcatcgccg gtacgatgcc tatgcctgat tatcccgaag aagagccgcc gcttttaggc
     8461 ttttttatgg tgggagcata tcaggaaata ctcggcaata tgcacaatct tttcggcgac
     8521 actgccactg ctgatgttgt tgtaggggaa gacggacaat ttaccgtcat cgattacgat
     8581 gaaggaaaca ccgttgccga tatgctcgaa tacgtttatc aagatccgaa agagctgatg
     8641 aaacgctatc gcgaacaaat cgaacattca gaccttcctg cctcgcaggc tatgtctttc
     8701 ttaaaagaac tcgaagcggg gcttaatggt tatacctatt tggaagacga atagacgcat
     8761 caaggcatcg gatatgccgt ctgaagcccg attttcttcc tcaaacacca atcaccacga
     8821 ccgattgaaa ccaattacaa ggaatcatta cgatgcaata cagcacactg gcaggacaaa
     8881 ccgacaactc cctcgtttcc aataatttcg ggtttttgcg cctgccgctt aattttatgc
     8941 cgtatgaaag ccaagcagat tgggtcatta ccggcgtgcc ttatgatatg gcggtttcag
     9001 ggcgttccgg cgcgcgtttc ggtcctgaag ccatccggcg cgcctccgtc aacctcgctt
     9061 gggagcaccg caggtttcca tggacatttg atgtgcgcga acgcctgaac attattgatt
     9121 gcggcgactt ggttttttct tttggcgaca gcagggattt tgtcgaaaaa atggaagcgc
     9181 acgccggcaa attactttct tccggcaaac gctgtttgag tttgggcggc gaccatttca
     9241 ttaccctacc gttgttgcgc gcccacgccc gctatttcgg caaactcgca ctgattcatt
     9301 ttgacgcgca caccgacacc tacgacaacg gcagcgaata cgaccacggt acgatgttct
     9361 ataccgcccc caaggaaggc ctcatcgacc cgtcccgttc cgtacaaatc ggcatacgca
     9421 ccgaacacag taaaaaattg ccttttactg tgttgaccgc cccccaagtc aatgaagaca
     9481 gtgttgaaga gaccgtccgt aaaatcaaag aaaccgtcgg caatatgccc gtttacctga
     9541 ctttcgacat agactgcctc gacccgtcgt tcgcccccgg gaccggtacg cccgtatgcg
     9601 gcggcttgag cagcgacagg gcattaaaaa tcctacgtgg gctgacggat ctcgacatcg
     9661 tcggtatgga tgttgtagaa gttgccccct cttacgacca atccgacatt accgctttgg
     9721 ccggcgccac aattgccttg gaaatgcttt accttcaagg tgcgaaaaag gactgaacgt
     9781 ccggcatccc ccgggttttc gccgtgccgt tcaaacggcg tattcagtct aatgaaaatt
     9841 caaatactga aacaaaagtt gcccggagcc gcatatcgga aagacggtga aatatctaaa
     9901 tatatcttat aaaacaatta gttaaatatt atttttccga tttttcggga cggtcttttt
     9961 tacggaggtc aatatgatga aattgggttt caaaccgata cccctcgcca ttgccgcagt
    10021 attgtgcgcc ctggttttgg cactgcccgt acccgacggg gtcaagcctc aggcttggac
    10081 gctgctggcc atgtttgtcg gtgtgattgc cgccattatc ggcaaggcca tgccgttggg
    10141 cgcgctgtcg attattgccg tcgggttggt cgcagtaacc ggcgtaaccg ccgacaaacc
    10201 gggcgcggcg atgagcgatg cgttgagtgc gttcgccaat ccgttgattt ggctgattgc
    10261 catcgcagtt atgatttcgc gcggtttgct caaaacaggg ctggggatgc gtatcggata
    10321 tttgtttatc gccgtttttg gaagaaaaac gctgggcatc ggttacagtc tcgctctttc
    10381 cgaactgctg ctggctcccg ttaccccttc caataccgcg cgcggcggcg gcattataca
    10441 tccgattatg cagtcgattg ccggcagtta cggctccaat cccgcaaaag gcacagaagg
    10501 caagatgggt aaatatttgg ctttggtcaa ctatcattcc aatcccattt cgtcggctat
    10561 gtttattact gcaactgccc ccaacccttt aatcgtcaac ttgattgccg aaaatttagg
    10621 cagtagtttc cgtctttctt ggggggcgtg ggcgtgggca atggctgttc ccggcgttat
    10681 cgcctttttc gttatgcctt tgattttata ttttttgtat ccgcctgaaa ttaaagaaac
    10741 gcccaatgcc gttcaatttg ccaaagaccg tctgagggag atgggtaaaa tgtcggcaga
    10801 cgaaatcatt atggcggtca ttttcggtat cttgctgctg ttgtgggcag atgttcccgc
    10861 ccttattacc ggcaatcacg cttttagtat caacgccacc gccaccgcat ttatcggatt
    10921 aagcctgctt ttgctttccg gtgtattgac ttgggacgat gttttgaaag aaaaaagtgc
    10981 gtgggatacg attatttggt ttggcgcatt gattatgatg gccgcatttt taaataaact
    11041 cggactgatt aaatggttct ccggagtgtt ggcggaaagt gtcggcggtt tgggcgttag
    11101 cggcacggct gcgggcgtaa tcctcgtgct tgcttatatg tatgcgcatt atatgtttgc
    11161 cagtactact gcacatatta ccgctatgtt cggcgcattt ctcgctgctg ccgtttcact
    11221 gaatgcaccg gcgatgccga ccgcgctgat gatggcggcc gcatccaaca ttatgatgac
    11281 cctcactcat tatgcgaccg gtacttcgcc tgtgattttc ggttcgggct acaccacaat
    11341 gggagaatgg tggaaggcgg gttttatcat gagcgtagtc aattttctga tttttttcgt
    11401 tatcggcagc atttggtgga aagttctggg gtattggtaa gggaaaaata aaataaattt
    11461 ccaatctgtg tttatttgat tgggcgacta ttatcgtgaa atatgccgtc taaagccttc
    11521 agatggcata tttgtgcgct tgaatgttgc agaaagcggc aggcggcggt gtaggaaaag
    11581 tcaaacaaaa accaaaccgc ctatcaactt ctgataaaca taagcattaa ataatcagaa
    11641 ggttattcaa ttacctaaac gcaaatttcc ctgccgtatc acatctattg aaaataatac
    11701 atcaaccggc tcggaagcag cctgatcagg tgtttctact tgcggcgatg aatcggcagc
    11761 cggttcggta taggcagtcg gcgtgccgtc ggattgggta tttaaatgcg gttgcgcctc
    11821 gggcgtgtgt acatcaggca cttcgggcgt gcgtgtctcg gatatttcgg cagagttggt
    11881 ttcctcagtt tgttcaatga cttcagcttg gctgtatgag gaagaaccct gtatccacgc
    11941 cagcgatttg agcggcatct tcatcttgcc gtttttgccg caggtcaggc agacggccga
    12001 tccggtgcgg tctttgagta cagcatcgac tttctcgggc gcgatggttt taccctgtgt
    12061 ttttgcccat tgcgcaatac tttttttcag agaggcgatg tcaaggttgt tcttaccgta
    12121 agggtcgcgg aaggcggcaa gccacaggtt gcgatccgca tcttcattga gccccgccat
    12181 ttgatagatg acggaggcgg gcgagccgct ggcgatggtt ttggcaaact cgagcgcgtc
    12241 gggcgatttc atgcggatgc agccgtgact ccgaaccccg gggacgctgg ccggcgcatt
    12301 ggtcccgtgt atgcccaaac cgagtttggg gtcgcctaag cggacaaaaa ccggccccaa
    12361 agggttgtcc gggccggcgg ctatggtttt tacgccgtcg ccgcgttctt tctgtatgga
    12421 tttggggatg taccaaacag ggttataggc tttcgcaccg attttatgtt cgcctagatt
    12481 ggtttgcgtc atcgcccgac ctactgcaac gggataaacc ttggtcagtt tgccgtcggt
    12541 gtagaggaac aggcgttgct gagggatgtt aatgaagaca tgttgacctt gtgcgacggg
    12601 ggagacatcg ggaatgacgg tgtttgcgta tgaaaaaccg cttatcaata gtgcagcagt
    12661 gcggcagatt gttttattca tatcaaaata tggtgtgtgt ccgataggtt ttcggcaaat
    12721 catacctgaa accgtaccaa tttgtgcgaa aatatgcgct tcggtacagt gcggacggat
    12781 tgggtaatgg caacggaaac aaatgtcgcg gaaatttccg ccttggatta tgaaggcagg
    12841 ggtgtggcaa aggtcggcgg caaaacggtt tttattaaaa gggcattact tgattgtttg
    12901 atgctgggtt ggttcaggct ttaactcagg aatatttaca tcataatgaa ggtttttaaa
    12961 caacagcttg aacaactcgg cgcgcaaaac caatatcgtt cgattccgga tttgattcat
    13021 caagggcggt atattacgcg ggaaaactgc aaaatgctga atatgtcgtc taatgattat
    13081 ttgggtttgg catcagatga aaacttgcgc cggtcttttt tgcagcaata cggcggtaat
    13141 tttccctctt ttaccagttc ttcatcgcgt ttattaacgg gcaactttcc tatttatacc
    13201 gatttggaag agcttgtcgc acaacgtttc caacgggaaa gcgcgttatt gttcaacagc
    13261 ggctatcacg ccaatctcgg tattttgcct gctttgacga cgacgaaaag tttgattttg
    13321 gcagataaat ttgttcacgc cagtatgatt gacggcatcc gtttgagccg gtgtgcgttt
    13381 tcccgttatc gtcataatga ttatgaacat ttgaaaaatc tgcttgaaaa aaacgtcgga
    13441 aaatttgacc gcacttttat cgttaccgaa tctgttttca gtatggacgg cgatgtggcg
    13501 gatttgaaac agcttgtcca attaaaaaaa cagtttccca atacttatct ttatgtggat
    13561 gaagcccacg caatcggtgt ttatgggcaa aacggattgg ggattgccga acgggataat
    13621 ttgattgccg agattgattt actggtcggc actttcggta aagccttagc ctcggtgggg
    13681 gcgtatgccg tctgcaacca agtattgaaa gaatgtttga ttaatcaaat gcgcccattg
    13741 attttttcaa ccgcattgcc gccgtttaat gtggcttgga cttattttat ttttgaacga
    13801 ttgccgcaat tctcaaaaga aagaagccat cttgagcagt taagtgcatt tttacggcgg
    13861 gaagtggcgc atcggacgca aataatgccg agccaaacct gtatcgtccc ctatatttta
    13921 ggcgggaatg aagccgccct tgccaaagcg gaatatctgc aaaggcaggg ttattattgc
    13981 ctgcccatca gaccgccgac agtacccaaa aacacatcca gaatccgcct gtctttaacg
    14041 gcagatatga caacggatga agtgcggcag tttgcggtgt gcctgtaagg atatgatatg
    14101 aaaacaaaat tttacaatca tcaaggcgga catttaatcc tgtattttgc aggttgggga
    14161 acgccgcccg atgctgtaaa tcatttgatt ttgccggaaa atcacgattt attgatttgc
    14221 tatgattatc aagatttaaa tttggatttt gatttttccg cctatcggca catccgtttg
    14281 gtggcgtggt caatgggcgt ttgggcggca gagagggcat tgcaaggaat aagattaaaa
    14341 tccgcaacgg cagtgaatgg cacaggtttg ccttgcgatg ataatttcgg tatcccttgc
    14401 accgttttta aaggcacatt ggagaacctc acggaaaaca cccgtttaaa atttgaacgc
    14461 agaatgtgtg gcgataaagc atcttttgaa gattaccaac aatttcccgc acgcccgttt
    14521 ggcgaaattc atcaagaact tatcgcactt tttgcgatga tcgggcaaga tagacgtaca
    14581 gatcttatcc gctggacaaa tgccttggtc ggatcgggcg ataaaatttt tatgcctgcc
    14641 aatcagcacc gatattggac accgcgttgc accgttcggg aaattgacgt cggacattac
    14701 ctgttttcaa gattcaccca ttggtcggca ctatggaatc actgactgcc ataaataaat
    14761 cgcgcattcg gcaggctttc caaaaagcat taaacgatta tgaccggcac gccttaatcc
    14821 aacaaaaaat gacgattaat ttaatgacgc atttgcaaga ttatttgccg gatatgccat
    14881 tggaaaacgt gttggaattg ggctgcggct caggaatgtt gagtgccttg ctgcaaaaac
    14941 agatttcagc gaattattgg ttatttaatg atttgtgcga tgtgcagccc caactggctg
    15001 aaaaactgcc gcaatccttt gatttttatt gcggcgatgc ggaaaacttt ccttttcaac
    15061 gacaatttga cttaatcgca agcgcatctg ccgtgcaatg gtttcatcaa cccgacgctt
    15121 ttatcgccca ttgcaaaaca ggcttgaaag caaacggatt attggcggtt gcaacctttg
    15181 gcaaagacaa tttaaaagaa gtccgccaaa ttacaaatat aggcttaaat tacccgactt
    15241 tatcccaatg gcagacttgg ttagccaaag attttgagct tttatggtgt gaggatttta
    15301 aggtaatact agactttgat acgccgttag atgtactcaa acaccttaaa tatacaggcg
    15361 taacagccac gaaccaaaaa aattggacaa gaaaaaatct caatgaattt attggcgatt
    15421 acttgtcggc gttcagtatg ccgtcgggca aagtgcacct gacttatcat ccgttatttt
    15481 ttatcgcgcg ctactctgcg gcgggcaggc aataaggcag cttatgggca aagttatttt
    15541 tatatcgggt attgatactg atgtgggtaa aaggtaatat ggcgaggctt gtgcagaagg
    15601 catattgtta aacgttaaat tatggtatga tttaaaactt acaagtctat ttcagtaaat
    15661 cgttaataat aaaagcggac aatggccgtt gcaggcggtc agctatccgc tcgttacggt
    15721 atcgggagta tcctttggaa aactcattaa ttatcggttt ggcactggcg gtattgctga
    15781 tgcttttggt tatgcgtgcg aagcagggta agaaaacacc gaagcgcaaa tcccaaggtg
    15841 tcggcaatac gcaggggcag acacccggaa gcaatgattc ggactgggtc gatcagattg
    15901 gacaatcggt ttcagacggc acgcaacccg actggtcttg gaacgaaagt gccgagaccg
    15961 catccgccgc cgtatccgcg caagaagtcg atccgcttac ggagtatcag gtttataagc
    16021 aattcggtta tcagggcaag gctgccgaat ctttggctgc ctatctggac ggcattccgg
    16081 atggtgaagc gaaacctgaa aaccttatcc gcgagctgct cgatatcaat ctcgaagtgg
    16141 gggatgtcga tgttttggca gacaatctgc aaaaatacgg caaactgatt ccttccgaac
    16201 ttttggcaaa atatatcgaa caggcattac agcgcgattc aaaccatttg cgtatccgtg
    16261 tcttggcgga agaaggtttg ggatggggca ctcaggagat tgaaaaacgt gcggaaggcg
    16321 gttctgcgac ggcagcttcc gcatcgcccc cgccggatgc cggcggtaag gcttatgaag
    16381 ccgaagaaat caagcgcatc ccgattgtgc ggggcaaaaa agacgtgtcc ggaatcagtc
    16441 aagaggaaat cggtgcgatt gccggtttgg ttcgcgccga tcaaggtgcg aaaatcctta
    16501 aagacaaagt cagctatgaa acggcatcga aacaatacga ccgtgccatc caaacttccg
    16561 aaaaacctgc aaacctgatt atcgatgcgt tgaaactcga ttaccaacac gcggacatag
    16621 accgttttgc cggacatttg tggaaacttt accaaacgtt gggcaactac ggcaggcagg
    16681 ttaaagagcg gatgctgggg tgggggtaca gcttgggtta ccatgaagtt ttcgatgatt
    16741 tggaaaaagg gccgaacgac cggcaaatca aagacatcgg tatggggcac gggtatctgc
    16801 cgaaaaatat acagaaattc aaatcgcaac atcgggattt ggtgcttcaa gattcttcgt
    16861 tgatcaacac cggttcgtct ccggcagacg atgcggttaa ggaagtagag tcgttgctga
    16921 tgtatggtca gattgaagcg gcaatggatg tgttggagca ggcggtattg aaatatcccg
    16981 acgagtccca gctttatatt acgttgatcg atatttatga acgtactgaa gattgggata
    17041 ggttggggca gtttttaagg gtattgaggg aacgtgcgga caggcttcct gaagaggtcg
    17101 ttatgctgat gagccggctg ctgcagcgta tgaatcaaaa tattaaaaaa ataaaacggt
    17161 acggaaaata aaaatggaag ttcaactgcc gaaaattaaa acagtacgcg taatgttggc
    17221 ggggatgacg gcgcagcagg aatccgtttt caaaatggca ttcaaaatgc acaataccac
    17281 ccgttatgaa acagtatccc cttcagacgg cagtgccgtg cccgatttgg ttttggcgga
    17341 taccgatgcc gagggcggtt ttgaactttg gaaagagctt gccgagcgtt ataaggatat
    17401 acccgtcgcc gtctgttcgg agaaagttcc cgattctgaa gttccctacc tgcccaaacc
    17461 gattcggttt gaaacattgt ttcctatgct ccgcaaattg ttgcagggcg agaatgttta
    17521 tgggaaatcg tttattgcac ccgcagaccg gtcggcgaaa aataacggga atgtgcagcg
    17581 tacggttacg atacgccagt ttaacccgaa taaaggatta ttgggggcgt tgcggtttgc
    17641 ggaaaagaac aggcaggaca tcgctatctt gcatggaaat aagccggtcc ttattgtttt
    17701 cccctcgata caacgggttt tgctgacaga aagtgtgcaa aaactcgaag aattgtgcaa
    17761 agacgaaaat ttgcaggtca gctgcaagac tgttcccgat aacccgcaat ggcgcgaaaa
    17821 ggctaaagta ggcattatgt cctgtatgtg gcagttttcc atttggacag tgcagggcag
    17881 gttgatttat ccgatttctc ccgatactcc gtttacgttg aaatcttggc caaacctgac
    17941 ccggttggca aatgtgccgg ggtcgatacg cttgtcggca tttctgacca aggcatccgt
    18001 caaccttaac gtgttgtata aagtgatgcc tttaaacctc aatgatattc tgaattatct
    18061 tgcggcaacc tatacaaccg ggtttttgtc ggtagattta aaaacggttt cacaacaggc
    18121 atactccgat atggcggata aaataaatat cggagccgat tctgcctctg atagtgaaat
    18181 gatgaaaaaa gcggaaaaaa tcacaacatc atcccaatcc cagtcgcgcg gtcttctgca
    18241 aaggctgatg aaaaaactgt tgggcagcta agaggcggag agatgagaga aaataaaatt
    18301 attttcacag gacctgtcgg cgtagggaaa accactgcca ttgcggctat ttcggacgaa
    18361 gcactcgttc agaccgatgc ttccgcatcc gatatgactt tggataggaa aaggaatacg
    18421 acagtggcga tggactacgg ggccatcagc ttggatgagg ataccaaagt ccatttatat
    18481 ggtacgcccg gtcaggaacg gttcaacttt atgtgggaaa tcttaagcca aggcagtatg
    18541 ggtttggtct tgcttttaga taatgcccga accaatccgt tgaaagattt ggaattcttt
    18601 ttacattcgt ttcgagggct gctggagaag gcacccgtcg ttgtcggtat taccaagatg
    18661 gatatacgct ctcagcccgg tatcgacgtg tatcacaaat atcttgcaaa acataatctt
    18721 aatgttccgg tttttgaaat tgatgcccgt aaggaagatg acgtaaaaca attggttagc
    18781 gcaatgttat tttctattga tccgggactg gaggtttaat atggaatcaa cactttcact
    18841 acaagcaaat ttatatcccc gcctgactcc tgccggtgca ttttatgccg tatccagcga
    18901 tgcccccagt gccggtaaaa ctttgttgca cagcctgttg aaagcggatg cggacgaaat
    18961 ggtcagcagt gagaagctgc ttacttgggc ggacaccgcc gacatcgata ccgctttgaa
    19021 cctgttgtac cgtttgcaaa aactcgaatt cctctatggc gatgaaaacg gtcattcaga
    19081 cggcatcaat ttgtcggacg agcaattgcc gttgctgatg gaacaattgt ccggcagcgg
    19141 taaggcgtta ttggtcgatc ggaacggtct gtatcttgcc aacgccaatt tccatcatga
    19201 ggcggcggaa gagttggggt tgttggcggc agaagtcgca cagatggaaa aaaaataccg
    19261 gctgctgatt aagaacaacc tgtatatcaa caataacgct tggggcgttt gcgatccttc
    19321 cggtcagagc gaattgacat ttttcccatt gtatatcggt tcaaccaaat ttattttggt
    19381 tatcggcggc attcccgatt tgggcaaaga ggcatttgtt actttggtaa ggattttata
    19441 ccgccgttac agcaaccgcg tgtaaaactt gggagagagg aggggttatg cagcaattat
    19501 tgatttcaat ccttgaagat ttaaacaata catctacgga tattatcgcg tctgccgtta
    19561 tctcaaccga cggattgccg atggcgacaa tgcttccttc acatttgaat tcggacaggg
    19621 taggggcgat ttctgccact ttgcttgctt tggggagtcg ctcggtgcag gaactcgcct
    19681 gcggggaatt ggaacaagtg atgattaaag gaaaatcagg ctatatcctt ttaagtcagg
    19741 cgggtaaaga tgccgtgttg gtgctggtgg caaaagaaac cggcagactt ggtttaatcc
    19801 tattggatgc caaacgtgcg gcaaggcata ttgcggaagc catataacat ataaagattg
    19861 cgggcttgca gataaagtgc aatcgattgt caatttatat tgacacgttc ggtatttctg
    19921 ttttattatt cgcgcttatt ccccgatagc tcagtcggta gagcgacgga ctgttaatcc
    19981 gcaggtccct ggttcgagcc caggtcgggg agccaaattt caaaaccctc taagtatttt
    20041 cttagagggt tttgttttac cggcggtcag aaacgcattt ttgagatgat tgttttgaga
    20101 tggaataaaa tctttgcaaa attcctttcg tgatggttat gaaaaaatag gggctgtcct
    20161 ggacaactag gataaactcg attttatagt ggattaacaa aaaccagtac ggcattggct
    20221 cgc
//
LOCUS       DAXIDM010000029        19907 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000029 DAXIDM010000000
VERSION     DAXIDM010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19907
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.029"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(368..922)
                     /locus_tag="ACFOAE_000858"
     CDS             complement(368..922)
                     /locus_tag="ACFOAE_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884375.1"
                     /translation="MKKIIASALIATFALAACQDDTQARLEQQQKQIEALQQQLAQQA
                     DDTVYQLTPEAVKDTIPAEAQANGNNGQPVTGKDGQQYIYDQSTGSWLLQSLVGAAAG
                     AFIGNALANKFTRTGNQDSPVARRARAAYHQSAHPNARTSRDLNTRSLRAKQQAAQAQ
                     RYRPTTRPPANYRRPAMRGFGRRR"
     gene            complement(1007..1507)
                     /locus_tag="ACFOAE_000859"
     CDS             complement(1007..1507)
                     /locus_tag="ACFOAE_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884376.1"
                     /translation="MNAMPQTAAQNETLHICSIIVDDAQDFSPMLLDAGRDDTLISES
                     MIPQIRTVAALIAAERHDFSRSSPAEFTDAADFFAARILVLGVRRFHLDVSLLQILKT
                     ANSRARRFAEKHRLFFTPAQAELSLNKHKNRRLLTVETEHEVENKGNPVANSLAFVRK
                     LHTLPL"
     gene            1911..3107
                     /locus_tag="ACFOAE_000860"
     CDS             1911..3107
                     /locus_tag="ACFOAE_000860"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HFC6884377.1"
                     /translation="MQNYLTPNFAFAPMIPERASGSRVWDTEGREYIDFSGGIAVNAL
                     GHCHPALADALNTQMHKLWHISNIYTTRPAQELAQKLVKNSFADKVFFCNSGAEANEA
                     ALKLARKYARDRFGGGKSEIVACINSFHGRTLFTVSVGGQPKYSKDYAPLPQGITHVP
                     FNDIAALEAAVGEQTCAVIIEPIQGESGILPATAEYLQTARRLCDRHNALLILDEVQT
                     GMGHTGRLFAYEHYGIVPDILSSAKALGCGFPIGAMLATEKIAAAFQPGTHGSTFGGN
                     PMACAVGSRAFDIINAPETLNHVREQGQKLQTALRSLGEQTGVFKQVRGMGLLLGCVL
                     DEAYRGRASEITAAALKHGVMILVAGADVLRFAPSLLLNDEDMAEGLRRLEHALTEFA
                     ATSDNP"
     gene            complement(3210..4454)
                     /gene="clpX"
                     /locus_tag="ACFOAE_000861"
     CDS             complement(3210..4454)
                     /gene="clpX"
                     /locus_tag="ACFOAE_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFC6884378.1"
                     /translation="MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHED
                     GNDGTSSESVGQTSEEPGKLPTPAEIVANLNDHVIGQEQAKKALAVSVYNHYKRLRHP
                     KAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQ
                     IITKLLGKCDFDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VASVPPQGGRKHPNQEFINVDTTNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSK
                     DENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDALINILTEPKNALVK
                     QYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGL
                     KKVVVGKAVIEEGREPELVFES"
     gene            4644..5015
                     /gene="rbfA"
                     /locus_tag="ACFOAE_000862"
     CDS             4644..5015
                     /gene="rbfA"
                     /locus_tag="ACFOAE_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFC6884379.1"
                     /translation="MRKPQRGYARQDRVKEQIMRELAELVRTGLKDPRAGFITVNEVE
                     VTRDYSHATVFYTILNQDAREITEEVLEHARGHLRSELAKRIKLFKIPELHFKYDESL
                     ERGMNLSALIDQVAAEKPVED"
     gene            5048..5971
                     /gene="truB"
                     /locus_tag="ACFOAE_000863"
     CDS             5048..5971
                     /gene="truB"
                     /locus_tag="ACFOAE_000863"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFC6884380.1"
                     /translation="MNTGKPQKRAVNGVLLLDKPEGLSSNTALQKARRLFRAEKAGHT
                     GVLDPLATGLLPVCFGEATKFSQYLLDADKAYTATLKLGEASSTGDAEGEIVATARAD
                     ISLAEFQTACKALTGDIRQVPPMFSALKHEGKPLYEYARKGIVIERKARYITVYAIDI
                     AEFDAPKAVIDVRCSKGTYIRTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEA
                     LANLNETERDSLLLSCDVLVSHFPQTVLNDYAVHMLRCGQRPRFEEDLPSGTPVRVYT
                     EIGEFVGLAEYQKEICRLKALRLMNTAASAA"
     gene            6188..8374
                     /locus_tag="ACFOAE_000864"
     CDS             6188..8374
                     /locus_tag="ACFOAE_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HFC6884381.1"
                     /translation="MKTDIQTELTQALLSHEKVWANEEKTILAKNILLDLVEKTDPTI
                     IGLLLNNDELKRHFFVEVNGVLVFKLQDLRFFLDKHSVNNSYTKYANRIGLTDGNRFL
                     KDNSDIVLDFPFKDCVLNGGQSTEEGEEIYFKRSNSQPASQPASQPASQPASQLYTKL
                     TRKRQEIFFNQTLAFDEIDRLFDAKAFSKFSRYTADGKQAVGEIKRHSDGTPAENLII
                     KGNNLIALHSLAKQFKGKVKLIYIDPPYYFVKKKQQDSFGYNTNFKLSTWLTFMKNRL
                     SIAKELLTDDGIIVISIDDDGNAYLKILLDEIFGFENFIGNLPTIMNLKGNNDEYAFA
                     GTHEYTLVFAKNKDKSTFYEFPIDEDNFLEKWEEDEIGFYKKGAPMRATGTEDKREDR
                     PEMFYPFLVKNNTVSTITDEEFSQIYNKDLEVFNDDFIQKLKEKYENLGYNFILPIAD
                     KQWGRWRWGYSIKNKARLQTDIIVSQSKNGISLYKKQRPELDDLPTKKPKTIFYKPEY
                     SSGNGTEQMKNLFGEKAFKNPKPEELIQDFITITTNESDIVLDYHLGSGTTAAVAHKM
                     NRQYIGIEQMDYIETLAVERLKKVIDGEQGGISKAVNWQGGGEFVYAELAPFNETAKQ
                     QILACEDSDGIKTLFEGLCERYFLKYNVSVNEFSQIIQEPEFQSLALDEQKQMVLEML
                     DLNQMYVSLSEMDDEQFAGCLNDDDKALSREFYQSAKNQAEKKDGE"
     gene            8364..11138
                     /locus_tag="ACFOAE_000865"
     CDS             8364..11138
                     /locus_tag="ACFOAE_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFC6884382.1"
                     /translation="MANNKTLFDWVEDRKSTLEEIEQTDFFALPEFVERNLKYPFFEW
                     QKSALENFVIFDRASKLKDFPDIKNRPTHLLFNMATGAGKTMMMAALILYYFEKGYRH
                     FLFFVNQNNIVDKTENNFIDPAHSKFLFTEKILQGDQVIPIHKVETFSPHSDGIEIKF
                     TSIQKLYNDIHTERENQTTLADLHELNLVMLGDEAHHLNAQTKGKKQGELDLEVELKA
                     NAGDAEFERKGWEHMVLELLLNKNGNPGQNVLLEFTATPPEKADVQQKYADKIITKFG
                     LKEFLQKGYTKEINLVSSTLSKKERVLHALLFAWYRHQIALKYGIANFKPVMLFRSKT
                     VDESKADYLAFLNWVENVQADDFSFLKTFSMSLNDSDNANEQGKTRTEQALKFMQENG
                     FEFAHLANWIKQNYQKHNIIITNSETNKSKTEKTDSETEKLLNNLEAVDNPIRAIFTV
                     GRLTEGWDVLNLFDIVRLYEGQNGGGSNKKSCKTANTTVSEKQLIGRGVRYFPFSFED
                     KQPNKRKFDNDMQHELRILEELFYYTHDEQSRYITELKNELRKDGYLPEKDDDKVLAT
                     FKLKSEFADNENFKNLLIWANKKIPNPNAKSNNADSLKANPQTLSFQIHGNQLLQETQ
                     FTADKNDEKVKQLGIQNNFSQTIKMSEMERHIFNKALHIKGKNSQSLFHFNRLQSKLN
                     IQNRNELQNNLLKDWQIEFLGLEQDKQVRPDDKLAGCLKILEMVEKHLNESDKPFIGT
                     KEFTPKTLWEIFGTPKQKWVKKDDIKTAIAMQNDWYVMDNFAGTGLEEALIQFISARL
                     GDLKSQYDIHLIRNEEVFKLNNFANGEGFMPDFILLLKDKQKSSSNGVNDFLHYQIFI
                     EPKGEHLVETDGWKEEFLEAITVEYGMDKILQKDTPHYRLIGLPFFTDHQKNGQFTES
                     FPLGVASLKK"
     gene            complement(11279..12451)
                     /locus_tag="ACFOAE_000866"
     CDS             complement(11279..12451)
                     /locus_tag="ACFOAE_000866"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFC6884383.1"
                     /translation="MKRDLSKMTCIEDLRRVAKRKMPRMFYDYIDSGSWTETTYRENT
                     SDFKDIRFRQKVLVNMEGRSLETKMIGQDVKMPVAIAPTGFTGMAHADGEILAARAAE
                     KFGIPFTLSTMSICSIEDVAENTSAPFWFQLYVMRDREFMENLIKRAKDAKCSALVLT
                     ADLQVLGQRHKDIKNGLSAPPKPTIANLINLATKPEWCMKMLNTERRTFRNIVGHAKN
                     VGDLSSLSSWTSEQFDPRLSWDDVARIKDLWGGKLIIKGIMEPEDAEKAAKSGADALI
                     VSNHGGRQLDDTVSAIKALPDIVSAVGSDIEVWMDSGIRSGQDILKAWALGAKGTMIG
                     RAFLYGLGAYGEEGVTRALEILYKEMDISMAFTGHRDIQDVDASILRGKDWGRETV"
     gene            12801..13247
                     /gene="iscR"
                     /locus_tag="ACFOAE_000867"
     CDS             12801..13247
                     /gene="iscR"
                     /locus_tag="ACFOAE_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003690 - double-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HFC6884384.1"
                     /translation="MRLTTKGRFAVTAMLDLAMNAQTGAVKLSAISERQNISLSYLEQ
                     LFGKLRRAGLVESLRGPGGGYILAAPAARINIAQIIAAAEDRLDATQCGSKANCHHGA
                     PCLTHDLWENLNKTINDYLGSVTLQSIIEQKNNGDGSRVVQFTHIH"
     gene            13276..14490
                     /locus_tag="ACFOAE_000868"
     CDS             13276..14490
                     /locus_tag="ACFOAE_000868"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IscS subfamily cysteine desulfurase"
                     /protein_id="HFC6884385.1"
                     /translation="MTVKTPVYLDYAATTPVDKRVAEKMIPYLTETFGNPASNSHSFG
                     WEAEEAVEKARADIAALINADSKEIVFTSGATESNNLAIKGAAHFYKSKGNHLITVKT
                     EHKAVLDTMRELERQGYEVTYLDVQENGLVDLDVLKAAIREDTILVSVMWVNNEIGVV
                     QDIPAIGEICRERKIIFHVDAAQACGKVPVDVEAAKIDLLSMSAHKVYGPKGIGALYV
                     RRKPRVRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAFRIAKEELEQDMAHYRKLRDI
                     FLKGIEGIEEVYVNGDLEHRAPNNLNVSFNFVEGESLIMAVKELAVSSGSACTSASLE
                     PSYVLRALGRNDELAHSSLRITFGRMTTEEEVQFAAELIKSKIGKLRELSPLWEMFKD
                     GIDLNSIEWAAH"
     gene            14556..14684
                     /locus_tag="ACFOAE_000869"
     CDS             14556..14684
                     /locus_tag="ACFOAE_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884386.1"
                     /translation="MNEQDLDLDNLDNLLEDFDGVTVEGGVDSENDDGCEGGACKI"
     gene            14754..15140
                     /gene="iscU"
                     /locus_tag="ACFOAE_000870"
     CDS             14754..15140
                     /gene="iscU"
                     /locus_tag="ACFOAE_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HFC6884387.1"
                     /translation="MAYSDKVIDHYENPRNVGTFDKGDDSVGTGMVGAPACGDVMRLQ
                     IKVNDEGIIEDAKFKTYGCGSAIASSSLITEWVKGKSLDDALAIKNSEIAEELELPPV
                     KIHCSILAEDAVKAAVADYRKRQENR"
     gene            15227..15547
                     /gene="iscA"
                     /locus_tag="ACFOAE_000871"
     CDS             15227..15547
                     /gene="iscA"
                     /locus_tag="ACFOAE_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003764837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HFC6884388.1"
                     /translation="MITLTENAAKHINDYLAKRGKGLGVRLGVKTSGCSGMAYNLEFV
                     DEADGDDLIFEGHGARIYIDPKSLVYLDGTQVDYTKEGLQEGFKFENPNVKDSCGCGE
                     SFHV"
     gene            complement(15507..15728)
                     /locus_tag="ACFOAE_000872"
     CDS             complement(15507..15728)
                     /locus_tag="ACFOAE_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor A"
                     /protein_id="HFC6884389.1"
                     /translation="MGGKVQHNKGKIRDNALKALVKSDLFRHKVERKRKGKGSYNRQE
                     AKKWRDGFDTVPPFLCLKRGSFRRSRRSL"
     gene            15810..16310
                     /gene="hscB"
                     /locus_tag="ACFOAE_000873"
     CDS             15810..16310
                     /gene="hscB"
                     /locus_tag="ACFOAE_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001671 - ATPase activator activity
                     [Evidence IEA];
                     GO_function: GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA];
                     GO_process: GO:0044571 - [2Fe-2S] cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly co-chaperone HscB"
                     /protein_id="HFC6884390.1"
                     /translation="MSQYFTLFRIEPAFDIDTENLEQTYRALAARFHPDKFASASAFE
                     QKQAVMMSSTINDAYRTLKNPIDRAAYLLKTSGIDADAPEHTAFAPEFLMQQMEWRET
                     LMEARAGNDLESLKNLDNEIRDEQEKLFCGLKQSFARQDYDTAAQQVRQGRFLDKLRN
                     EISSAL"
     gene            16408..19158
                     /gene="gyrA"
                     /locus_tag="ACFOAE_000874"
     CDS             16408..19158
                     /gene="gyrA"
                     /locus_tag="ACFOAE_000874"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFC6884391.1"
                     /translation="MTDATIRHDHKFALETLPVSLEDEMRKSYLDYAMSVIVGRALPD
                     VRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGDVIGKYHPHGDTAVYDTIVRMAQ
                     NFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGS
                     EHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLSDTVNACLRLLDAPDTEIDELID
                     IIQAPDFPTGATIYGLSGVREGYKTGRGRVVMRGKTHIEPIGRNGEREAIVIDEIPYQ
                     VNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNENAEVVLNQLYKLTP
                     LQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAEGK
                     AVALSNIDEIIKLIKESPNAAEAKDKLLARPWRSSLVEEMLTRSGLDLEMMRPEGLAA
                     NIGLKEQGYYLSEIQADAILRMSLRNLTGLDQEEIVESYKNLMGKIIDFVDILSKPER
                     ITQIIRDELEEIKTNYGDERRSEINPFGGDIADEDLIPQREMVVTLTHGGYIKTQPTT
                     DYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRN
                     SRGRPINNVIQLEEGEKVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGI
                     KAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEYWEKSGNDEAEDADIETEISD
                     GIEDETADSENALPSGKHGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEESGLQV
                     LTATANGYGKRTPIADYSRKNKGGQGNIAINTGERNGDLVAATLVGETDDLMLITSGG
                     VLIRTKVEQIRETGRAAAGVKLINLDEGETLVSLERVAEDESELSDASVISNVTEPEV
                     EN"
     gene            19315..19718
                     /locus_tag="ACFOAE_000875"
                     /pseudo
     CDS             19315..19718
                     /locus_tag="ACFOAE_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060537127.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5653 a         4994 c         4632 g         4628 t
ORIGIN      
        1 ccttttccgc tttggcaacg attgaaaatt tccgtaaatt caaatatcta gattccttcc
       61 tgcacgggaa tgacacggaa gggtttcaga tgcagggtgg gcattcctgc ccacccaatc
      121 ccgcccttgc aacggtgggc aagaatgctc gccctatggt ctgacggttc gatatgatgc
      181 cgtctgaaaa cccaacggcg gcatgacaat gccgccctgc caacgcacgt aaatcagaat
      241 tgccatcccg acatcaaacg cttggaaaca aaatgccgtc taaaaatcaa acggcaacat
      301 aacaatgccc ctaacaaatg caaaaatgcc gtctgaaagc ccttcagacg gcattggcac
      361 gccggattta ccgccttctg ccgaaaccgc gcatggcggg gcggcggtaa ttggcgggcg
      421 ggcgcgttgt cgggcggtaa cgctgcgcct gcgccgcctg ttgttttgca cggaggctgc
      481 gcgtgttcaa atccctgctg gtgcgcgcat tgggatgtgc ggactgatgg taggctgcac
      541 gcgcgcgccg ggcgacggga ctgtcttggt tgcctgtccg tgtgaatttg tttgccagcg
      601 cgttgccgat aaacgcgcct gccgccgcgc cgaccaggct ttgcagcagc cagcttcctg
      661 tcgattggtc gtaaatatac tgctgcccgt ctttaccggt aacgggttgc ccgttgttgc
      721 cgtttgcctg tgcttcggca ggaatggtgt ctttgactgc ttcgggagtc agttggtaaa
      781 ccgtatcgtc tgcctgctgt gcgagctgct gttgcagggc ttcaatctgt ttctgctgct
      841 gttcgagccg cgcctgcgtg tcgtcttggc aggcggcgag tgcgaatgtt gcgataagcg
      901 cggaggcgat gatttttttc atgtgtgtcc tgtttgggtg gaaaatcggt tttattgtat
      961 cgccgtcggg aattttggca agcattctgc cgacaaatcg tgatgtttac aggggcaggg
     1021 tgtgcagttt gcggacaaat gcgaggctgt tggcgactgg gttgcctttg ttttcgactt
     1081 cgtgttcggt ttctacggtc agcaggcggc ggtttttgtg tttgttcagg ctcaattcgg
     1141 cttgtgcggg tgtgaaaaac aggcggtgtt tttcggcaaa gcggcgggcg cggctgttgg
     1201 cggttttcaa aatctgaagc agcgatacgt ccagatggaa gcgtcgcacg cccaatacga
     1261 gaatccgtgc ggcaaaaaaa tcggcggcat cggtaaactc ggcggggctg ctgcggctga
     1321 agtcgtgccg ttcggcggct atcagggcgg caacagtgcg gatttgcgga atcatcgatt
     1381 cgctgataag tgtgtcgtcc cgccctgcat cgagaagcat gggggaaaaa tcctgtgcat
     1441 catcgacaat aatgctgcaa atgtgcaggg tttcgttttg tgcggcggtt tggggcattg
     1501 cattcatggt cattttcctg attctgtcgt gtgttgccga atcgggcgac ctgtgtgaag
     1561 gtaacaaaaa agccgccccg ttttcgagcg gcctgttttg cgtatgggat ggatttcaag
     1621 caagcgcaaa aaagtaccgc acgtctgtgt ggtaccaata gcaataagcg gttgtaaatt
     1681 ttttgccttg catgatgaaa tgccgtctga agataaaaat attggggaga ttctaaatca
     1741 aaacgctgcc gcgcctcaag cattttatcg aaattttttt gatttttcat ctatccgatt
     1801 gaaaatattt cggtttattt ttaccgctgc ccgatattgt cggcaatttc cctttatctg
     1861 ctttgaaaaa cggtgcataa tcccgagcaa aaccgcaatc aggagcaatt atgcaaaact
     1921 atctgacccc caatttcgcc tttgccccga tgattcccga acgcgcttca ggcagccgcg
     1981 tttgggatac ggaagggcgt gaatatattg acttttcagg cggcatcgcc gttaacgcgc
     2041 tgggacactg ccaccctgcc cttgccgatg ctttaaacac gcagatgcac aagctgtggc
     2101 acatttccaa tatctatacg acacgtccgg cgcaggaatt ggcgcaaaaa ttggtgaaga
     2161 acagctttgc cgacaaggtt tttttctgca actcgggcgc ggaagcgaat gaggcggcgt
     2221 tgaagctggc gaggaaatac gcgcgcgacc gtttcggcgg aggaaaaagc gaaatcgtcg
     2281 cctgtatcaa cagtttccac ggacgcacgc tgtttaccgt gtccgtcggc ggtcagccga
     2341 aatacagcaa ggattatgca cccctgccgc aaggcattac gcacgttccg ttcaacgata
     2401 ttgccgcgct ggaagctgcc gtcggcgaac agacctgcgc ggtcatcatc gagccgatac
     2461 agggcgaaag cggcatcctg cccgccactg cggaatattt gcaaaccgcg cgccgtctgt
     2521 gcgaccggca caatgcgttg ttgattttgg acgaagttca aaccgggatg gggcatacgg
     2581 gcaggctgtt tgcctatgaa cattacggca ttgttcccga tattttgagt tcggcaaaag
     2641 ccttgggctg cggctttccg atcggcgcga tgctggcgac agaaaagatt gccgccgcct
     2701 tccaaccggg cacgcacgga tcgactttcg gcggcaaccc gatggcgtgt gcggtcggca
     2761 gccgcgcctt cgacatcatc aacgcgccgg aaactttaaa ccatgtccgt gaacaggggc
     2821 agaaacttca gacggcattg cggtctttgg gagaacaaac gggcgtgttt aagcaagttc
     2881 gcggcatggg gctgctgctc ggctgcgtgt tggacgaagc ctatcgcgga cgcgcatccg
     2941 aaatcaccgc cgccgccttg aaacacggcg tgatgatttt ggttgcgggt gcggacgtat
     3001 tgcgtttcgc gccttcgcta ctgttgaacg atgaggatat ggcggaaggt ttgcgacgtt
     3061 tggaacacgc gctgacggaa tttgccgcga catcagacaa tccgtaaaac tcaaatgccg
     3121 tctgaaggcg ggaaggcttc agacggcatc agaaacaaaa aaccgcttca gaaacgtggt
     3181 tcaacgttcc gaagcggttt tgtttgccat caggactcga acaccaattc cggttccctg
     3241 ccctcttcga tgactgcctt accgaccacc acttttttca agcctttcaa atcaggcagg
     3301 cggtacatgg tatcgagcag gcagcgttcg acgatggaac gcaggccgcg cgcgccggtt
     3361 ttgcgctcca ttgcctgacg cgcgatggaa cgcaatgcgc cttcttcaaa ttccaactcg
     3421 acattttcca taccgaacaa ggcttgatac tgcttgacca aagcattttt cggctcggtc
     3481 aaaatattaa tcagcgcgtc ctcatccagt tcttctagtg ttgcaatcac gggcaaacgt
     3541 ccgattaatt ccggaatcag accgaattta atcaaatctt ccggttcgac gatgccgaac
     3601 agcttggtaa tgtcggcatt ttcgtccttg ctgtgaacag acgcaccgaa accgataccg
     3661 cctttttcag tacgctggcg gatgactttt tccaagcctg caaacgcgcc gccgcagata
     3721 aacaggatgt tggtggtatc gacgttgata aattcctgat tcggatgctt gcggccgcct
     3781 tggggcggaa cgctggccac cgtaccttca atcagtttca gcaaggcttg ttgcacgcct
     3841 tcgccggaca cgtcacgcgt gatggacgga ttgtcgcttt tgcgtgaaat cttatcgatt
     3901 tcgtcgatat agacgatgcc gcgttgggct ttttcgacat cgaaatcaca tttgcccaag
     3961 agtttggtga tgatttgctc gacatcttcg ccgacataac ctgcttcggt cagcgtggtt
     4021 gcatctgcca tcacgaacgg cacatccagt ttgcgcgcca aagattgcgc cagcagggtt
     4081 ttacccgatc cggtcgggcc gataagcagg atgttggatt tcgacaattc gacattagct
     4141 ccggctttcg ggtggcgcag gcgtttgtaa tggttgtaca ccgacaccgc caaggctttc
     4201 ttggcttgtt cctgaccgat aacgtggtcg ttgaggttgg cgacgatttc ggcgggcgtg
     4261 ggcagcttgc cgggctcttc cgatgtctgt ccgacacttt ccgaagacgt gccgtcattt
     4321 ccgtcttcat gcaatatttc aatacagttt gagacgcatt cgtcacagat aaaggcgttt
     4381 tcgccctcaa ttaaatgttt gacgtgtgat ttggattttc cgcaaaagga acaggtacgg
     4441 ttttcgttgg acatagcttt ctttacaatg tatgcgttac agaaacggca cgcgccgttc
     4501 gggttgccaa gtataataac tatatccgtt cttatcaatg tattacctta aaatcccgcc
     4561 gattaggcta taatacgccc tttcgcaacc gccccggcgg caaaaatgcc gtctgaaacc
     4621 aaatctgaaa tctgaggata ttcatgagaa aaccccaacg cggctatgcc cgccaagacc
     4681 gtgtcaaaga acaaattatg cgcgagcttg ccgaactcgt ccgtaccgga ctgaaagacc
     4741 cgcgcgccgg cttcattacc gtcaacgaag tcgaagttac ccgcgattac agccacgcca
     4801 ccgtgttcta caccatttta aaccaagacg cgcgcgaaat tacggaagaa gtgctggaac
     4861 acgcgcgcgg acacctccgc agcgaattgg ccaaacgcat caagctgttc aaaatccccg
     4921 agctgcattt caaatacgac gaatccttgg aacgcggtat gaacctgtcc gcccttatcg
     4981 accaagtagc ggcggaaaaa ccggttgaag actgacggat atgcccatgc cgtccgaaca
     5041 tcgaaccatg aatacaggca aaccccaaaa acgtgccgtc aacggtgttt tgctcttgga
     5101 caaacccgaa ggcctttcca gcaacaccgc gctgcaaaaa gcgcggcgtt tgttccgtgc
     5161 cgaaaaagcc ggacataccg gcgtgctcga tcctttggca accggacttt tgcccgtctg
     5221 cttcggcgaa gcgaccaagt tctcccaata cctgctggat gccgacaaag cctacaccgc
     5281 cacgctgaaa ctcggcgaag ccagcagcac gggtgatgcc gaaggcgaaa tcgttgccac
     5341 cgcccgtgcc gatatttcct tagccgaatt tcagacggcc tgcaaagcat taacgggcga
     5401 catccgccaa gtgccgccaa tgttttccgc gctcaagcac gaaggcaaac cgctgtacga
     5461 atacgcccgc aaaggcatcg tcatcgaacg caaagcgcgc tacattaccg tttacgccat
     5521 cgatattgcc gaatttgacg cgcccaaagc cgtcatcgac gtacgttgca gcaaaggcac
     5581 ctacatccgc accctcagcg aagacatcgc caaacacatc ggcacgttcg cccacctgac
     5641 cgccttgcgc cgcaccgaaa ccgccggctt taccatcgcc caaagccaca cgcttgaggc
     5701 cttggcaaat ttgaacgaaa cagaacgcga cagcttgctg ctatcctgcg acgtattggt
     5761 ttcacacttt ccccaaaccg ttttaaacga ttatgccgtc catatgctcc gctgcggaca
     5821 acgtccgcgt ttcgaggaag acctaccttc cggcacgccg gtacgcgttt acactgaaat
     5881 tggagaattt gtcggtttgg cagaatatca aaaggaaata tgccgtctga aagccttgcg
     5941 cctgatgaac acggcggcat ccgccgcctg aacgacggtt aaaaatacgg gctgtgtttg
     6001 aataatgtgt tgatatttcc gcaaaatccc gacacactcg gacaccctcc ccgcttatcg
     6061 caactttgcg aacgcccccc gaaacagaaa agacatcaaa ggattgattt tattagaatt
     6121 tatttgcaaa gccatttgcc gttacacaag aatggcacat taaaatgact gatgaggatt
     6181 tataacgatg aagacagaca ttcaaaccga attaacccaa gccctgctat cacacgaaaa
     6241 agtatgggcg aacgaagaaa aaaccatttt agccaaaaac attctgttgg atttggtgga
     6301 aaaaaccgac ccgaccatta tcggtttgtt attgaataat gatgagttaa aacgccattt
     6361 ctttgtggaa gtgaatggtg ttttggtgtt taaattgcag gatttacgtt ttttcttgga
     6421 caaacacagc gtcaataatt cctacacaaa atacgccaac cgcattggtt tgacggacgg
     6481 caaccgcttt ttgaaagaca attcggatat tgtgttggat tttccgttta aagattgcgt
     6541 attgaatggc ggacaaagca ccgaagaagg cgaagagatt tattttaaac gcagtaatag
     6601 ccagccagcc agccagccag ccagccagcc agccagccag ccagccagcc aattatacac
     6661 taaattaacc cgaaaaagac aagaaatctt ttttaatcaa acgcttgctt ttgatgaaat
     6721 cgatcggctt tttgacgcaa aagcattctc aaaattctct cgctataccg cagacggcaa
     6781 acaagcggtt ggcgaaatca aacgtcattc agacggcaca cccgccgaaa atctcattat
     6841 caaaggcaat aatctgatag ccctacattc gcttgccaaa cagtttaaag gcaaagtgaa
     6901 gttgatttat attgatccgc cttattattt tgttaaaaag aaacaacaag atagttttgg
     6961 ttataacact aactttaaat tatctacttg gcttacattt atgaaaaatc gtttatcaat
     7021 tgccaaagaa ttattaactg atgatgggat tattgttatt tccattgatg atgacggaaa
     7081 tgcttattta aagattttgt tagatgaaat ttttggattt gaaaatttta tcggaaattt
     7141 acccactatt atgaatttaa aaggtaataa tgatgaatat gcttttgcag gcactcacga
     7201 atacacacta gtctttgcta aaaataaaga taaatctact ttttatgaat ttccaataga
     7261 tgaagataat tttttagaga aatgggaaga agatgaaatt gggttttata aaaaaggagc
     7321 tccaatgcga gcaacaggaa ccgaagataa aagagaagat agacctgaaa tgttctatcc
     7381 ttttttggta aaaaataaca cagttagtac aattacagat gaagaatttt ctcaaatcta
     7441 taataaagat ttagaagtat tcaatgatga ttttattcaa aaactaaaag agaaatacga
     7501 aaatcttgga tacaatttta ttttacctat tgctgataaa caatgggggc gttggcgttg
     7561 ggggtattca ataaagaata aggcaaggct gcagacggat attattgtta gccaatctaa
     7621 aaatggaatt tccttgtata aaaaacaaag acctgaatta gatgatttac ctacaaaaaa
     7681 acctaaaact attttttata aacctgaata cagtagtggt aatggaactg aacagatgaa
     7741 aaatcttttt ggtgaaaagg catttaaaaa tcctaaacca gaagaactta tccaagattt
     7801 tattaccatc acaaccaacg aatccgacat cgtcttagac taccatcttg gtagtggcac
     7861 aaccgccgcc gttgcccaca aaatgaaccg acaatatatc ggtattgaac aaatggatta
     7921 tattgaaacg cttgccgttg aacgcttgaa aaaagtgatt gatggcgagc aaggcggtat
     7981 ttccaaagcc gtgaattggc aaggtggtgg cgagtttgtt tatgccgaac ttgccccatt
     8041 taacgaaacc gcaaaacaac aaattttggc ttgcgaagat tcagacggca tcaaaacgct
     8101 gtttgaaggt ttatgcgaac gctatttctt gaaatacaac gtcagcgtaa atgaatttag
     8161 tcaaatcatt caagagcctg aatttcaatc cttggcatta gacgaacaaa aacaaatggt
     8221 gcttgaaatg ttggatttaa atcaaatgta tgtttcatta tccgaaatgg atgatgagca
     8281 atttgcaggt tgcttaaatg atgacgataa agcgttaagc cgtgaattct atcaatcagc
     8341 aaaaaatcaa gcggagaaaa aagatggcga ataataaaac gttatttgat tgggtggaag
     8401 accgcaaatc aacgctggaa gaaatagaac agacagattt tttcgcgctg cctgaatttg
     8461 tagaacgcaa tttaaaatat ccgttttttg aatggcaaaa atcggcttta gaaaactttg
     8521 tgatttttga ccgcgcttca aaattaaagg atttccctga catcaaaaac cgccctaccc
     8581 atttgctgtt caatatggca acaggtgctg gcaaaacgat gatgatggcg gcgttgattt
     8641 tgtattattt tgaaaaaggt tatcggcatt ttttgttttt cgtcaatcaa aataatatcg
     8701 tggataaaac ggaaaataat tttattgacc cggcgcactc aaaattttta tttaccgaga
     8761 agattttgca aggcgaccaa gttattccca ttcacaaagt agaaacgttt agcccacatt
     8821 cagacggcat tgaaattaaa tttaccagta ttcaaaaact gtataacgat atccacaccg
     8881 aacgggaaaa ccaaaccaca ttggcagatt tgcacgaatt gaaccttgtg atgctgggcg
     8941 atgaagcgca ccatttaaac gcacaaacca aaggcaaaaa acaaggcgag ttggatttgg
     9001 aagtggaatt aaaagccaat gcaggcgatg ccgaatttga acgcaaaggc tgggagcata
     9061 tggttttgga attgttgctc aataaaaatg gcaatcccgg ccaaaatgtg ctgttggaat
     9121 ttaccgccac gccacctgaa aaagctgacg tgcaacaaaa atacgctgat aaaatcatca
     9181 caaaatttgg tttaaaagaa tttttgcaaa aaggttatac caaagaaatc aatttggtat
     9241 ccagtacact gagcaagaaa gagcgggtgt tgcacgcttt attgtttgct tggtatcgcc
     9301 atcaaatcgc tttgaaatat ggcattgcca atttcaagcc tgtgatgttg tttagaagta
     9361 agacggttga tgaatcaaaa gcggattatt tggcattttt aaattgggta gaaaatgtgc
     9421 aagcagatga tttttcgttt ttaaagacat tttcaatgag cttaaacgat agcgataacg
     9481 ccaacgaaca aggcaaaacc cgcaccgaac aagccctaaa atttatgcag gaaaatggct
     9541 ttgagtttgc acatttagca aattggataa aacaaaatta tcaaaaacac aatatcatta
     9601 ttaccaactc cgaaaccaac aaaagcaaaa ccgaaaaaac cgacagcgaa acggaaaaat
     9661 tgctaaacaa tctggaagcg gttgataatc cgattcgtgc tatttttacg gtgggtagat
     9721 taaccgaagg ttgggacgtt ttaaatttgt ttgatattgt gcgtttgtat gaagggcaaa
     9781 acggcggcgg ttcaaataaa aaatcatgca aaacggcaaa tacaacggta tcagaaaaac
     9841 agttgattgg tcgaggcgtg cgttattttc cattttcgtt tgaagataaa cagccgaata
     9901 agcgtaaatt tgacaacgac atgcaacacg aattgcgtat tttggaagaa ttgttttatt
     9961 acacgcacga tgagcaatcc cgctatatta cagaactgaa aaacgagtta cgaaaagacg
    10021 gttatttgcc tgaaaaagac gatgataagg tattggcaac atttaaactc aaatctgaat
    10081 ttgcagataa tgaaaatttt aaaaacttat tgatttgggc gaataaaaaa atccccaatc
    10141 ccaatgctaa aagtaataat gcagacagcc taaaagccaa tccgcaaaca ctttcattcc
    10201 aaattcacgg caatcaactg ttgcaggaaa cgcaatttac agccgataaa aatgatgaaa
    10261 aggtcaagca acttggcata caaaataatt tttctcaaac cataaaaatg agtgaaatgg
    10321 aacggcacat cttcaataaa gcattacata tcaaagggaa aaatagtcaa tctttattcc
    10381 atttcaaccg tttgcaaagc aaactcaaca ttcaaaatcg caatgaattg caaaataact
    10441 tgttgaaaga ctggcaaatt gaatttttag gattagagca agataaacag gttcgcccgg
    10501 atgataaact tgcaggctgc ctgaaaatct tggaaatggt tgaaaagcat ttgaatgaaa
    10561 gtgataagcc atttatcggt acaaaagaat ttacgcctaa aacattatgg gaaattttcg
    10621 gcacgccaaa acaaaaatgg gtcaaaaaag atgatataaa aactgctatt gccatgcaaa
    10681 atgattggta tgtgatggat aattttgccg gaacgggttt ggaagaagcg ttaattcaat
    10741 ttatttcagc gcgtttgggc gatttgaaat ctcaatatga cattcattta atccgtaacg
    10801 aagaagtgtt taaattgaat aactttgcca atggcgaagg atttatgccc gactttattt
    10861 tattgctgaa agataaacaa aaatcttctt ccaatggcgt gaatgacttt ttgcattacc
    10921 aaattttcat tgagcccaaa ggtgagcatt tagtggaaac tgatggatgg aaagaagaat
    10981 ttttagaagc catcacagtg gaatatggga tggataagat cctgcaaaaa gatacaccgc
    11041 attatcgttt gatcggttta ccgtttttta ctgatcatca gaaaaatgga caatttacgg
    11101 agtcattccc tttaggtgtg gcatcgctta aaaaatagag tagtgcattg caggcagccc
    11161 cgtttgacaa aacttccttt acaaaagggc gttttgtcaa atagttcatt attaaaatac
    11221 agccaaattt taatgccgtc cgaaccatgt gttcagacgg catcgtattt ttcagtattt
    11281 aaaccgtttc cctaccccaa tctttacccc ttaaaatcga ggcatcgaca tcttgaatat
    11341 cgcggtgtcc cgtaaacgcc atagatatat ccatttcttt atacaggatt tccagcgcac
    11401 gggttacgcc ttcttcgcca tacgcaccca agccatacag gaacgcccga cctatcattg
    11461 tacctttcgc acccaaagcc cacgccttca aaatatcctg accgctgcgg atgccgctgt
    11521 ccatccaaac ttcgatgtcg ctgccgactg cactaacgat gtcgggcaag gctttgatgg
    11581 cggacacggt atcgtcgagc tggcggccgc cgtggttgga aacaatcaat gcgtccgcgc
    11641 cgcttttcgc tgctttttcc gcatcttcag gttccataat gcctttgata atcagcttgc
    11701 caccccacaa atctttaatg cgtgcaacgt cgtcccagct caggcgcggg tcgaattgtt
    11761 cggaagtcca tgaagacagc gaggacaaat cgccgacgtt tttggcgtgt ccaacgatat
    11821 tgcggaacgt gcggcgttcc gtgttcagca ttttcataca ccattcgggc ttggtcgcca
    11881 gattgattaa attggcgatg gtcggtttcg gcggcgcgga caggccgttt ttgatgtctt
    11941 tgtggcgttg ccccaaaacc tgcaaatcgg cggtcaaaac caatgccgaa catttggcat
    12001 ccttcgcgcg cttaatcagg ttttccataa actcgcggtc gcgcatcaca taaagctgaa
    12061 accaaaacgg cgcgctggtg ttctcggcaa cgtcttcaat cgagcagatg gacatggtgg
    12121 acaacgtaaa cggaataccg aacttctccg ccgcccgcgc cgccaaaatt tcgccgtctg
    12181 cgtgtgccat gccggtaaaa cccgtcggcg caatcgccac cggcattttc acatcctgcc
    12241 cgatcatttt agtctcaagg ctgcgtccct ccatattgac caatactttt tgacggaagc
    12301 ggatgtcttt gaaatccgaa gtattttccc gataagtcgt ttccgtccac gaacccgaat
    12361 cgatgtaatc gtaaaacata cgcggcattt tgcgcttggc aacgcggcgc aagtcttcga
    12421 tgcaggtcat tttgctcaaa tcacgtttca tcttgttttt ccctgtttga cagcctgatg
    12481 gaatatgccg tccgaaaccg cttgagcctt cagacagcat ttcaggcaat acccaaataa
    12541 atcactaaga tttagataat ctatatcaat atcaaaaata aatcaaatcg ttttgaaacc
    12601 gcttgccggc aaaatacccc gaccgccgct cctcaaaaaa cataaccaac tgatttaaaa
    12661 aaccaaacaa ataaagcaaa atcagactat accgccattt aaacaaacaa tcggcaacag
    12721 ctccccctta cttgactgaa acactcagat attggacaat tctccccact ataaaaaagc
    12781 cgacacgggc aaccaccacc atgagactga ccaccaaagg gcgtttcgcc gttaccgcta
    12841 tgctggattt ggcgatgaac gcgcaaaccg gcgccgtcaa actcagtgcc atcagcgaac
    12901 gccaaaacat atccctctcc tatctcgagc aattgttcgg caaactccgc cgcgccggac
    12961 tggttgaaag cctgcgcggg cccggcggcg gctacatcct cgccgcaccg gcggcacgca
    13021 tcaacatcgc ccaaatcatc gccgccgccg aagaccggct ggacgcaacc caatgcggca
    13081 gcaaagccaa ctgccaccac ggcgcgccct gcctgacgca cgatctttgg gagaatttaa
    13141 acaaaaccat caacgactac ctcggcagcg ttaccctgca aagcatcatc gaacagaaaa
    13201 acaacggcga cggcagccgc gtcgtccaat ttacacacat ccattaaata acacccgaaa
    13261 aagaaagagc aaaccatgac cgtcaaaacc cccgtttacc tcgactacgc cgccaccacc
    13321 cccgttgaca aacgcgttgc cgaaaaaatg attccctatc tgaccgaaac cttcggcaac
    13381 ccagcctcca acagccacag cttcggctgg gaagcagaag aagctgtaga aaaagcacgt
    13441 gcagacattg ccgccctgat taacgccgac tctaaagaaa tcgttttcac cagcggcgca
    13501 accgagtcca acaacctcgc tatcaaaggc gcggcgcact tctacaaatc taaaggtaat
    13561 cacctcatca ctgtaaaaac cgaacacaaa gccgtactcg acaccatgcg cgaactcgaa
    13621 cgccaaggtt acgaagtaac ttatctggac gtacaagaaa acggtttggt tgatttagac
    13681 gtactgaaag ccgccatccg cgaagacacc atcctcgttt ccgtaatgtg ggtaaacaac
    13741 gaaatcggcg tggttcaaga tattcctgcc atcggcgaaa tctgccgcga acgcaaaatc
    13801 attttccacg ttgacgcagc acaagcatgc ggcaaagtgc ctgtcgatgt cgaagccgcc
    13861 aaaatcgacc tgctctcgat gtccgcgcac aaagtgtacg gccccaaagg catcggcgcg
    13921 ctgtacgtcc gccgcaaacc ccgcgtccgc ctcgaagccc aaatgcacgg cggcggccac
    13981 gaacgcggct tccgcagcgg cacattgccg acccaccaaa tcgtcggtat gggcgaagcc
    14041 ttccgcatcg ccaaagaaga actcgaacaa gatatggcgc actaccgcaa actgcgcgac
    14101 atcttcctca aaggcatcga aggcatcgaa gaagtctatg tcaacggcga cctcgaacac
    14161 cgcgccccga acaacctgaa cgtcagcttc aacttcgtcg aaggcgaaag cctgattatg
    14221 gcggtgaaag aactcgccgt atccagcggc tccgcctgta cttctgccag tctcgaaccc
    14281 agctacgtcc tgcgcgcgct cggccgcaac gatgaactgg cgcactcatc cctgcgcatc
    14341 accttcggtc gcatgaccac cgaagaagaa gtgcaattcg ccgccgaact gattaaatcc
    14401 aaaatcggca aactgcgcga actgtcgccg ctgtgggaaa tgttcaaaga cgggattgat
    14461 ttgaactcga ttgaatgggc agcgcattaa agcgtaccaa catgccgtcc gaacctttag
    14521 acggcattcc aaaaacaaag caatcaagag aaaatatgaa cgaacaagat ttagatttgg
    14581 acaatctcga caacctgctt gaagattttg acggcgttac cgtggaaggc ggcgtcgatt
    14641 cggaaaacga cgacggctgc gaaggcgggg cgtgcaaaat ctaaacttca ggccgtctga
    14701 aaatcggcaa acaaaccact taaaccatca aaaaacatta aggaaaccac atcatggcat
    14761 acagcgataa agtaatcgac cactatgaaa atccgcgcaa cgtcggcaca ttcgacaagg
    14821 gagacgattc cgtcggcacc ggcatggtcg gcgcgcccgc ctgcggcgac gtcatgcgcc
    14881 tgcaaatcaa agtgaacgac gagggcatca tcgaagatgc gaaatttaaa acttacggct
    14941 gcggctcggc catcgcttcg tccagcctga ttaccgagtg ggttaaaggc aaaagcctgg
    15001 atgacgcgct ggcaatcaaa aacagcgaaa tcgccgagga gttggaattg ccgccggtaa
    15061 aaatccactg ctccatcttg gctgaagatg cggtaaaagc ggccgttgcc gactaccgca
    15121 aacgtcagga aaacagataa agcccttcag acggcatcat cccgcaatgc cgtccgaacc
    15181 acccgccgct tcaggtccgt ccggggcggt acaacaagga agaaatatga ttacccttac
    15241 cgagaatgcc gcaaaacaca tcaatgacta tctcgccaaa cgcggcaaag gcttgggcgt
    15301 acgcttgggt gtgaaaacca gcggctgctc ggggatggcg tacaaccttg aatttgtcga
    15361 cgaagccgat ggcgacgacc tgattttcga aggacacggc gcgcgcattt atatcgatcc
    15421 gaaaagcctg gtttatctgg atggcacgca agtcgattac accaaagaag gtttgcagga
    15481 aggtttcaaa tttgaaaacc ccaatgtcaa agactcctgc ggctgcggcg aaagcttcca
    15541 cgtttaaggc ataaaaacgg cgggaccgta tcaaaaccgt cccgccattt tttcgcttcc
    15601 tgcctgttgt agctgccttt gcctttcctt ttccgttcca ccttgtgccg gaacaaatcg
    15661 gatttcacta aggcttttaa agcattgtcg cgtattttgc ctttattgtg ctgcactttg
    15721 ccgcccatat tcagtccttt cgtttaagaa gcggcagatt ataaggcaaa aacagttttc
    15781 tgccaaaatc ttacatttat catcctacta tgtcccaata tttcaccctc ttccggattg
    15841 aacccgcttt cgatatcgac accgaaaact tggaacaaac ctaccgcgcc ttggccgccc
    15901 gtttccatcc cgataaattc gcttcagctt ccgcctttga gcaaaagcag gcagtgatga
    15961 tgtcttccac catcaacgat gcctaccgca ccttgaaaaa ccccatcgac cgcgccgcct
    16021 acctgctgaa aacatcgggc atcgatgccg acgcgccgga gcataccgct ttcgcccccg
    16081 aattccttat gcagcaaatg gaatggcgcg aaacgctgat ggaggcacgg gcaggcaacg
    16141 accttgaatc cttgaaaaat ctcgacaacg aaatccgcga cgaacaagaa aaactgttct
    16201 gcggtctgaa acagtcgttt gcccgacaag attacgacac agccgcacaa caagtccgcc
    16261 aaggcaggtt tctcgacaaa ctccgcaacg aaatttcctc ggcattataa tccgcaccgt
    16321 gtttcagacg gcgtaaccgc cgcaccgttc cgcgtcaaaa tatgctaaaa taagcaacaa
    16381 ttttttgcca tacgaaacat tgaaaccatg accgacgcaa ccatccgcca cgaccacaaa
    16441 ttcgccctcg aaaccctgcc ggtaagcctt gaagacgaaa tgcgcaaaag ctatctcgac
    16501 tacgccatga gcgtcattgt cgggcgcgcg ctgccggacg ttcgcgacgg tctcaagccg
    16561 gtacaccgcc gcgtactgta cgcgatgcac gagctgaaaa acaactggaa tgccgcctac
    16621 aaaaaatcgg cgcgcattgt cggcgacgtc atcggtaaat accaccccca cggcgatacc
    16681 gccgtatacg acaccatcgt ccgtatggcg caaaatttcg ctatgcgtta tgtgctgata
    16741 gacggacagg gcaacttcgg atcggtggac gggcttgccg ccgcagccat gcgctacacc
    16801 gaaatccgca tggcgaaaat ttcccacgaa atgctggcag acattgagga agaaaccgtc
    16861 aatttcggcc cgaactacga cggtagcgaa cacgagccgc ttgtactgcc gacccgtttc
    16921 cccacactgc tcgtcaacgg ctcgtccggc atcgccgtcg gcatggcgac caatatcccg
    16981 ccgcacaacc tttctgatac cgtcaatgcc tgcctgcgcc tgctcgatgc acccgacacc
    17041 gaaatcgacg aactgatcga cattatccaa gcccccgact tcccgaccgg ggcaaccatc
    17101 tacggcttga gcggcgtgcg cgaaggctat aaaacaggcc gcggccgcgt cgttatgcgc
    17161 ggtaagaccc atatcgaacc cataggcaga aacggcgaac gcgaagccat cgttatcgac
    17221 gaaatcccct atcaggtcaa caaagccaag ctggtcgaga aaatcggcga tttggttcgg
    17281 gaaaaaacac tggaaggcat ttccgagctc cgcgacgaat ccgacaaatc cggtatgcgc
    17341 gtcgttatcg agctgaaacg caacgaaaat gccgaagtcg tcttaaacca actctacaaa
    17401 ctgactccgc tgcaagacag tttcggcatc aatatggtgg ttttggtcga cggacaaccg
    17461 cgcctgttga acctgaaaca gattctctcc gaattcctgc gccaccgccg cgaagtcgtt
    17521 acccgacgta cgcttttccg gctgaagaag gcacgccatg aagggcatat cgccgaaggc
    17581 aaagcggtcg cactgtccaa tatcgatgaa atcatcaagc tcatcaaaga atcgcccaac
    17641 gcagccgagg ccaaagacaa actgcttgcg cgtccttggc gcagcagcct cgttgaagaa
    17701 atgctgacgc gttccggtct ggatttggaa atgatgcgtc cggaaggatt ggctgcaaac
    17761 atcggcttga aagagcaagg ttattacctg agcgagattc aggcagatgc tattttacgc
    17821 atgagcctgc gaaacctgac cggcctcgat caagaagaaa ttgtcgaaag ctacaaaaac
    17881 ctgatgggta aaatcatcga ctttgtggat atcctctcca aacccgaacg cattacccaa
    17941 atcatccgcg acgaactgga agaaatcaaa accaactatg gcgacgaacg ccgcagcgaa
    18001 atcaacccgt tcggtggcga cattgccgat gaagacctga ttccgcaacg cgaaatggtc
    18061 gttaccctga cacatggcgg ctatatcaaa acccagccga ccaccgacta tcaggcgcag
    18121 cgtcgcggcg ggcgcggcaa acaggcggct gccaccaaag acgaagactt tatcgaaacc
    18181 ctgtttgttg ccaacacgca tgattatttg atgtgcttta ccaatttggg caagtgtcat
    18241 tggattaagg tttacaaact gcccgaaggc ggacgcaaca gccgcggccg tccgattaac
    18301 aacgtcatcc agttggaaga aggcgaaaaa gtcagcgcga ttctggcagt acgcgagttc
    18361 cccgaagacc aatacgtctt cttcgccacc gcgcagggaa tggtgaaaaa agtccaactt
    18421 tccgccttta aaaacgtccg cgcccaaggc attaaagcca tcgcgctcaa agaaggcgac
    18481 tacctcgtcg gcgctgcgca aacaggcggt gcggacgaca tcatgctgtt ctccaactta
    18541 ggtaaagcca tccgcttcaa cgaatactgg gaaaaatccg gcaacgacga agcggaagat
    18601 gccgacatcg aaaccgaaat ttcagacggc atcgaagatg aaaccgccga cagcgaaaac
    18661 gcactgccga gcggcaaaca cggtgttcgc ccgtccggtc gcggcagcgg cggtttgcgc
    18721 ggtatgcgcc tgcctgccga cggcaaaatc gtcagcctga ttaccttcgc ccctgaaacc
    18781 gaagaaagcg gtttgcaagt tttaaccgcc accgccaacg gatacggaaa acgcaccccg
    18841 attgccgatt acagccgcaa aaacaaaggc gggcaaggca atattgccat taacaccggc
    18901 gagcgaaacg gcgatttggt cgccgcaacc ttggtcggcg aaaccgacga tttgatgctg
    18961 attaccagcg gcggcgtact tatccgcacc aaagtcgaac aaatccgcga aaccggccgc
    19021 gccgcagcag gcgtgaaact gattaacttg gacgaaggcg aaaccttggt atcgctggaa
    19081 cgtgttgccg aagacgaatc cgaactctcc gacgcttctg taatttccaa tgtaaccgaa
    19141 ccggaagtcg agaactgaaa atcatctccc gatgccgtct gaagattcag acggcattta
    19201 ttttatccct catccgtcat ccagcttctc acaatatagc ggattatagt caattaaaaa
    19261 caaggggctg tcctagataa ctagggaaat tcaaattaag ttagagttgc ccctatgaga
    19321 aaaagtcgtc taagccggta taaacaaata aactcattga actgtttgtc gcaggtgtaa
    19381 ctgcaagaac gacagcagag ttagtaggcg ttaataaaag taccgcagcc tattattttc
    19441 atcgtttacg attacttatt tatcaaaaca gtccgcattt ggaaatgttt gatggcgaag
    19501 tagaagcaga tgaaagttat tttgctgaac gacaaaacca tatcaatgga attgagaact
    19561 tttggaaccg ggcaaaacgt catttacgca agtttgacgg cattcccaaa gcgcattttg
    19621 agctgtattt aaaggggtac gaacggcgtt ttaacaacag tgagataaaa gttcaaattt
    19681 ccattttaaa acaattagta aaatcgagtt tatcctagtt atctaggaca gccccaaaaa
    19741 caaaatagta caatattcaa ctttgaaggt ctaaccatgg catactctgc ggacttaaga
    19801 aacaaagctt taaactatag tggattaaca aaaatcagga caagacgacg aagccgcaga
    19861 cagtacaaat agtacggcaa ggcgaggcaa caccgtactg gtttaaa
//
LOCUS       DAXIDM010000030        19874 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000030 DAXIDM010000000
VERSION     DAXIDM010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19874
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.030"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(121..630)
                     /locus_tag="ACFOAE_000876"
     CDS             complement(121..630)
                     /locus_tag="ACFOAE_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003662333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HFC6884392.1"
                     /translation="MTMILSILSLFFIIRLLFLAVSIKHEKALIAKGAKQYGKTNSTL
                     LAAVHTLYYLACFVWVWLSDTAFNGISLIGTLTVMASFVILSLIIKQLGEIWTVKIYI
                     LPNHQINRSWLFKTFRHPNYFLNIIPELIGIALLCQAWYVLLIGLPIYLLVLFKRIRQ
                     EEQAMATLF"
     gene            complement(962..1294)
                     /locus_tag="ACFOAE_000877"
     CDS             complement(962..1294)
                     /locus_tag="ACFOAE_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884393.1"
                     /translation="MQILSFQPDIAERMLEGTEGESVNENAQFVRTDNGYWIAWHEGV
                     AALLAPDTPPGIPCFWVEGAESLEELCVMVERGEFDEVEEFDGDDDEWLETAQGCGHH
                     GEACACGH"
     gene            complement(1339..1446)
                     /locus_tag="ACFOAE_000878"
                     /pseudo
     CDS             complement(1339..1446)
                     /locus_tag="ACFOAE_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            1585..2421
                     /gene="cysT"
                     /locus_tag="ACFOAE_000879"
     CDS             1585..2421
                     /gene="cysT"
                     /locus_tag="ACFOAE_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysT"
                     /protein_id="HFC6884394.1"
                     /translation="MLPLKTPGVLPGFKLSLGLTVLCLSLLVVLPFAMMAAKAAEIGW
                     GGFWNTIAEPNVLAAVWLSLRMSFYAMLTNVVFGTLVAWVLVRYEFPGKGLANALVDL
                     PFALPTAVTGIALATLYAPNGWIGRFFEPLGIKIAFTPVGIWIALVVVSLPFIVRAVQ
                     PVLEELSGEYEEAAATLGANRFTTFRRVLLPEITPALLTGAGMMFARATGEYGSVIFI
                     AGNIPMVSEILPLIITGKLEQFDVQGASAVALFMLLVSFVILFALNVMQWALGRRSGA
                     KG"
     gene            2676..3536
                     /gene="cysW"
                     /locus_tag="ACFOAE_000880"
     CDS             2676..3536
                     /gene="cysW"
                     /locus_tag="ACFOAE_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015419 - ABC-type sulfate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter permease subunit CysW"
                     /protein_id="HFC6884395.1"
                     /translation="MKPYSANPNLTEPRWLRVLLIAAALGFLLLMLVVPLVAVFYEAL
                     KGGWDLYLKSLNDPEAWSAIKLTLITALIVVPVNAVLGVAMAWLLTRFDFRGKQLLTT
                     LLDLPFSVSPVVAGLMFVLLFGAHTALGGWLEAQGIQIIFAIPGIILATLFVTFPFVA
                     REIIPLMQAQGDSEEQAALILGASGWQMFWRVTLPNIKWALLYGIILTNARAMGEFGA
                     VSVVSGHIRGETNTVPLLVEIFYNEYNFTGAFALSGVLALLALATLAVQNIITKLQDK
                     KLAAAERNAV"
     gene            3533..4606
                     /locus_tag="ACFOAE_000881"
     CDS             3533..4606
                     /locus_tag="ACFOAE_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HFC6884396.1"
                     /translation="MSITIQNLNKHFGNFHALKNINLNVPTGKLVSLLGPSGCGKTTL
                     LRIIAGLENADGGKILFDGQDVTAKHVRERKVGFVFQHYALFRHMNVFDNVAFGLTVL
                     PKSERPSKGQIRAKVEELLKLVQLSHLAKSYPHQLSGGQRQRIALARALAVEPKLLLL
                     DEPFGALDAKVRKELRTWLRDIHHNLGVTSILVTHDQEEALEVSDEIVVMNHGKIEQT
                     GSAEAIYRKPENAFVTEFLGETDAFEGRIEKGFWHYNGFAWKLDAQYKWQEQTATGYI
                     RPHEWQIAAEHETPMICAEIEKVHAVGALTHILVKHGKQDVHITLAGSDAARYPIAEG
                     KELKLIPKQVYVFSQNELIEYSI"
     gene            complement(4663..6189)
                     /gene="ilvA"
                     /locus_tag="ACFOAE_000882"
     CDS             complement(4663..6189)
                     /gene="ilvA"
                     /locus_tag="ACFOAE_000882"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HFC6884397.1"
                     /translation="MNTPLPYSNYLIRILTASVYDVAVETPLEPARSLSVRLKNNILL
                     KREDLQPVFSFKIRGAYNKMSKLPKDALACGVIAASAGNHAQGVALSAQRLGCRAVIV
                     MPETTPKIKVDAVKSRGGEVVLRGVSYNDAYDYAMELAEQEGLTYIAPFDDPDVIAGQ
                     GTVGMEIVSQHPDPIRAVFVPIGGGGLAAGVAAFIKQVRPEIKVIGVQTNDSCCMKQS
                     VEAGEIVHLKDVGLFSDGTAVKVVGNETFRLCKELLDEIITVDTDAVCGAVKDIFDDT
                     RSITEPAGALALAGLKAYIAREGAENQTLIAVTSGANMNFHRLRHVSERSELGEGNEG
                     IFAVTIPEERGSFLKFVNILGNRNITEFNYRYGDDEKAHIFVGLQAAGPQDLAVIGSR
                     LDEAGLPNVDLTDDEIAKIHIRYMVGGRTDKVENERLVSFEFPERPGALARFLNHMQG
                     GWNITLFHYRNHGADYGRILVGIDVPPHDAAAFDGFLESLGYSYHEETQNAAYKLFLA
                     "
     gene            6337..7506
                     /locus_tag="ACFOAE_000883"
     CDS             6337..7506
                     /locus_tag="ACFOAE_000883"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFC6884398.1"
                     /translation="MTAHKILPVLLSIILGVSHATAASPAPNKPAVHAAPTFQTPETL
                     TAAHIVIDLQSKQILSAKNINTPVEPAALTQLMTAYLVFKNMKSGNIRSEENLKIPES
                     AWASEGSRMFVRPGDTVSTDKLLKGMIALSANDAALTLAGRLGNGSIENFVQQMNKEA
                     RRLGMKNTVFKNPTGLSREGQVSTAKDLAQLSEALMRDFPEYYPLFSIKSFKFKNIEQ
                     NNRNILLYRDNNVNGLKAGHTESGGYNLAVSYSGNGRHILVITLGSESAETRASDNSK
                     LLNWALQAFDTPKIYPKGKTVAQIQISGGSKKTVRAGFLKEAYITLPHKEAKMAEQIL
                     ETIQPIPAPVKKGQILGKIKIRQNGYTITEKEIVALENVEKRSRWQRLWMRLTGQ"
     gene            complement(7631..8203)
                     /locus_tag="ACFOAE_000884"
     CDS             complement(7631..8203)
                     /locus_tag="ACFOAE_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003755233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFC6884399.1"
                     /translation="MTYEIQASVREAQGTGASRRLRREGQIPGILYGEGQEPVAIAVD
                     HKTVFYALEKESFHTALIKLSLNGETKDVIVRDFQMHPFRREVQHIDFQAVKADQLVR
                     IRVPLHIVNAENSQAVKLQGGRVSLLNTTVEVLALPANIPAFLDLDCAEVVAGDILHL
                     SDIKLPEGVESVSLKRNENLAVATVTGKKR"
     gene            complement(8270..9253)
                     /locus_tag="ACFOAE_000885"
     CDS             complement(8270..9253)
                     /locus_tag="ACFOAE_000885"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0006015 - 5-phosphoribose 1-diphosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009165 - nucleotide biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HFC6884400.1"
                     /translation="MAAYDSLMVFTGNANPELAQRVVRHLDISLGNASVSKFSDGEVA
                     VELLENVRGRDVFILQPTCAPTNDNLMEILTMADALKRASAGRITTAIPYFGYARQDR
                     RPRSVRVPISAKLVANMLYSAGIDRVLTVDLHADQIQGFFDIPVDNIYATPILLNDIK
                     QQRIENLTVVSPDIGGVVRARAVAKSLNADLAIIDKRRPKANVAEVMNIIGDIQGRTC
                     LIVDDMIDTANTLCKAAVALKERGAERVLAYASHAVFSGEAVSRIASSEIDQVVVTDT
                     IPLSEAAKNCDRIRQVTIAGLLAETVRRISNEESVSYLFNEEVMTGSMLLP"
     gene            complement(9420..9495)
                     /locus_tag="ACFOAE_000886"
     tRNA            complement(9420..9495)
                     /locus_tag="ACFOAE_000886"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9460..9462),aa:Gln,seq:ttg)
     gene            complement(9504..9579)
                     /locus_tag="ACFOAE_000887"
     tRNA            complement(9504..9579)
                     /locus_tag="ACFOAE_000887"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9544..9546),aa:Gln,seq:ttg)
     gene            complement(9592..9667)
                     /locus_tag="ACFOAE_000888"
     tRNA            complement(9592..9667)
                     /locus_tag="ACFOAE_000888"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9632..9634),aa:Gln,seq:ttg)
     gene            complement(9675..10520)
                     /gene="ispE"
                     /locus_tag="ACFOAE_000889"
     CDS             complement(9675..10520)
                     /gene="ispE"
                     /locus_tag="ACFOAE_000889"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFC6884401.1"
                     /translation="MNIADGRQAFPAPAKLNLDLRITGKREDGYHNIESIFCLIDLQD
                     TVYLKLRDDGKIILHNPVDGMPQEADLSYRAASLLQKYARNPAGVEIWLDKKIPTGAG
                     LGGGSSDAATVLLVLNRWWQCGLTQRQLIDSGAALGADVPFFIFGKNAFARGIGDRLD
                     EMDIPKQWYVIVKPPVHVSTAKIFTHEGLTRNSASSIMPTFQNLQPFRNDMQAVVFKE
                     YPEVWKAYSELSRYGFALMTGSGACVFTACQDRNSAYNIYRQVSDLYEAYLAEGLSKH
                     PLLSV"
     gene            complement(10530..11111)
                     /locus_tag="ACFOAE_000890"
     CDS             complement(10530..11111)
                     /locus_tag="ACFOAE_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein LolB"
                     /protein_id="HFC6884402.1"
                     /translation="MKHTVSASVILLLTACAQLPQNNENLWQPSEHTRSFTAEGRLAV
                     KAEGKGSYANFDWTYQPPVETININTPLGSTLGQLCQDRDGALAVDGKGNVYQAESAE
                     ELSRQLVGFKLPIQYLHIWADGRRVAGAPYRILPDGILEQYGWTVGRTADSGGQVRTL
                     QLNNGNLNIRLVFTEIGMPSETETPERCAARTR"
     gene            complement(11251..13089)
                     /locus_tag="ACFOAE_000891"
     CDS             complement(11251..13089)
                     /locus_tag="ACFOAE_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC6884403.1"
                     /translation="MLPARFTILSVLAAALLAGQAYAAGAADAKPPKEVGKVFRKQQR
                     YSEEEIKNERARLAAVGERVNQIFTLLGGETALQKGQAGTALATYMLMLERTKSPEVA
                     ERALEMAVSLNAFEQAEMIYQKWRQIEPIPGKAQKRAGWLRNVLRERGNQHLDGLEEV
                     LAQADEGQNRRVFLLLAQAAVQQDGLAQKASKAVRRAALKYEHLPEAAVADVVFSVQG
                     REKEKAIGALQRLAKLDTEILPPTLMTLRLTARKYPEILDGFFEQTDTQNLSAVWQEM
                     EIMNLVSLHRLDDAYARLNVLLERNPNADLYIQAAILAANRKEGASVIDGYAEKAYGR
                     GTGEQRGRAAMTAAMIYADRRDYTKVRQWLKKVSAPEYLFDKGVLAAAAAVELDGGRA
                     ALRQIGRVRKLPEQQGRYFTADNLSKIQMFALSKLPDKREALRGLDKIIEKPPAGSNT
                     ELQAEALVQRSVVYDRLGKRKKMISDLERAFRLAPDNAQIMNNLGYSLLSDSKRLDEG
                     FALLQTAYQINPDDTAVNDSIGWAYYLKGDAESALPYLRYSFENDPEPEVAAHLGEVL
                     WALGERDQAVDVWTQAAHLTGDKKIWRETLKRHGIALPQPSRKPRK"
     gene            complement(13254..14090)
                     /gene="panC"
                     /locus_tag="ACFOAE_000892"
     CDS             complement(13254..14090)
                     /gene="panC"
                     /locus_tag="ACFOAE_000892"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HFC6884404.1"
                     /translation="MQIIHTIQELRAWRKNAGKVAFVPTMGNLHEGHLALVREAKKRA
                     DNVVVSIFVNRLQFGQGEDFDKYPRTLQQDADKLEAEGVAVVFAPDEKELYPNVEQRY
                     NVEPPNLQNELCGKFRPGHFRGVATVVSKLFNIVAPDVACFGKKDYQQLAVIKGLTED
                     LNFDVEIVPVDTGRAEDGLALSSRNQYLSAAERDEAPRLSRELKAVAESLAQGSLDYA
                     GLERQAADHLTAAGWVVDYVEIRRADTLEVARAGDKKLVVLAAARLGTTRLIDNLEIK
                     LP"
     gene            complement(14213..15004)
                     /gene="panB"
                     /locus_tag="ACFOAE_000893"
     CDS             complement(14213..15004)
                     /gene="panB"
                     /locus_tag="ACFOAE_000893"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HFC6884405.1"
                     /translation="MITVNTLQKMKAVGEKIAMLTAYESSFAALMDDAGVEMLLVGDS
                     LGMAVQGRQSTLPVSLRDMCYHTECVARGAKNAMIVSDLPFGAYQQSKEQAFAAAAEL
                     MAAGAHMVKLEGGVWMAETTEFLQMRGIPVCAHIGLTPQSVFAFGGYKVQGRGGKAQA
                     LLNDAKAHDDAGAAVVLMECVPAELAKKVTETVSCPTIGIGAGADCDGQVLVMHDMLG
                     IFPGKTAKFVKNFMHGQSSIQAAVRAYVEEVKAKTFPAAEHIFAD"
     gene            complement(15146..15221)
                     /locus_tag="ACFOAE_000894"
     tRNA            complement(15146..15221)
                     /locus_tag="ACFOAE_000894"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15186..15188),aa:Thr,seq:tgt)
     gene            complement(15256..15331)
                     /locus_tag="ACFOAE_000895"
     tRNA            complement(15256..15331)
                     /locus_tag="ACFOAE_000895"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15296..15298),aa:Thr,seq:tgt)
     gene            15497..16288
                     /locus_tag="ACFOAE_000896"
     CDS             15497..16288
                     /locus_tag="ACFOAE_000896"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HFC6884406.1"
                     /translation="MARHPYRRLRPAKSSFPEVGISEEGNIRSLHLGSDTIQSSMNLD
                     HPSELVLSYSRAMMGWLLFTDALPQHITQIGLGGGSFARWIDTYLPDTRQTAVDINPQ
                     VIAIARSLFELPFEGEKFEIIEADGAEYIKVFRHNTDVILVDGFDGEQIIDALVEEPF
                     FRDCRNALSSDGIFVTNWWSGDKRYQRFIERLLSVFEGRVLELPAESHGNVAVMAFQS
                     SPKEQNIDKLKKRADKLSNAYGLDFHRMLAGLKASNPNNGKHFHL"
     gene            16343..16984
                     /locus_tag="ACFOAE_000897"
     CDS             16343..16984
                     /locus_tag="ACFOAE_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFC6884407.1"
                     /translation="MLKPETIHISGPAGILETIHIPSEQVPARGVAVINHPNPLQGGT
                     NTNKVIQTAAKALSKLGFHCYLPNLRGVGGSEGTHDYGRGETQDCLAVIDYARAQHPE
                     APEFALSGFSFGGYVATFAAQARIPDLLLLIGAAVCHYTGRPEPSAVPNVAKTLMIHG
                     AEDEVVEIEKALKWAEPQDLPVITIAGSTHFFHGKLIVLRDTILRFAPVCLNG"
     gene            complement(17062..17985)
                     /locus_tag="ACFOAE_000898"
     CDS             complement(17062..17985)
                     /locus_tag="ACFOAE_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFC6884408.1"
                     /translation="MKKRNNPLPLLNGVKPSYLVLPHEKQFYGLPLLHFLCIRFPFVG
                     ADDWRRRLNSGFVVGSDGAALDEHTLFEPGKVMFYYRETSRESEPRIPFEEKILHIDE
                     HLIVVDKPHFLPVIPSGRFLRETLLTRLRLRPELQHLNVEDITPLHRLDKDTAGVMLL
                     SHNPATRGAYQTMFQNKTVWKTYEALAPTRTDLPYPIDVVSRLVRGEKFFTTQEAEGE
                     PNAHTTVELIENRGEFSLYRLTPHTGKKHQLRVHMMGLGMPLLNDALYPVPSEAGSED
                     YRKPLKLLAKKIAFADPLSGRERVFCSGFCL"
     gene            18149..19018
                     /locus_tag="ACFOAE_000899"
     CDS             18149..19018
                     /locus_tag="ACFOAE_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="meta-pathway of phenol degradation family
                     protein"
                     /protein_id="HFC6884409.1"
                     /translation="MKRIFLPALPAILPLSAYADLPLTIEDIMTDKGKWKLETSLTYL
                     NSENSRAALAAPVYIQTGATSFIPIPTEIQENGSNTDMLAGTLGLRYGLTGNTDIYGS
                     GSYLWHEERKLDGNGKTRNKRMSDISAGISHTFLKDDKNPALIGFLESTVYEKSRNKA
                     SSGKSWLIGATTYKAIDPVVLSLTAAYRINGSKTLSSNTKYKAGNYWMLNPNISFAAN
                     DRISLTGGIQWLGKQPDRLDGKKESARNTSTYAHFGAGFGFTKTTALNASARFNVSGQ
                     SSSELKFGVQHTF"
     gene            19061..19483
                     /locus_tag="ACFOAE_000900"
     CDS             19061..19483
                     /locus_tag="ACFOAE_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="wall-associated protein precursor"
                     /protein_id="HFC6884410.1"
                     /translation="MKKQITAAVMMLSMIAPAMANGLDNQTFENQVFHTQADAPIQLA
                     ELSQKEMKETEGAALWFAPVLAGGGRFALTGFTRHGLNQAISRGGVGVSNKAIMNTMR
                     NPTKITSQSGGRTRFTGADGGVVLNSQGKVITTWGKPR"
     gene            19529..19777
                     /locus_tag="ACFOAE_000901"
     CDS             19529..19777
                     /locus_tag="ACFOAE_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884411.1"
                     /translation="MNIKNEIVALISKKIDGGQYSSLENFALSVLREKIIKNTVSSDE
                     KLLIINDFLSGFLEFDPETGKPVGETLKIEQMIDFFLV"
BASE COUNT         4952 a         5560 c         4657 g         4705 t
ORIGIN      
        1 cccgtgtatt gctgtaaatc ttagagatgg cggaatatag cggattaaca aaaaccagta
       61 cggcaaggcg aggcaacgcc gtactggttt ttgttaatcc gctataattg atgaaacggg
      121 ttaaaaaagt gttgccatcg cctgttcttc ttgtcggata cgcttaaata agaccagcaa
      181 ataaatgggc aggccaatca ataaaacata ccacgcttga cataataagg cgatgccaat
      241 cagttcgggt atgatgttta aaaaataatt ggggtggcgg aatgttttaa acaaccacga
      301 acgattaatt tgatgatttg gtaaaatata gattttaacc gtccaaatct cccccaactg
      361 cttaataatc aatgacaata tcacaaacga agccatcacc gtcagcgtac caatcaagga
      421 tatgccatta aaagcagtgt cagaaagcca tacccaaaca aaacacgcca aataataaag
      481 cgtatgaact gccgcaagca gcgtggaatt ggtttttccg tattgtttcg cccctttggc
      541 aatcaaggct ttttcatgtt taatagagac ggctaaaaat aacagtctga tgataaaaaa
      601 caggcttaaa atgcttaaaa tcattgtcat tgatgttttt ccattgaaat tgaaataaat
      661 ataaatcgga ttaatggtat ttttaattaa tgatgtttca gaccatcatg ctctataaac
      721 aattcccatt aagtccgcgc cgcaacctgc tataataagt ctgcaatcgg cgcaaatcaa
      781 tgctttgcgt ttattgccat cccaaaataa ttgatgatgc cttaattata ataccaagat
      841 aagttttttt attcaataaa atacaaaggg aagcgttccg cccattgcaa acagatgcaa
      901 tccaccgatt atttaaaaaa cggcaaagcc ttgcacccct tgcggcaagc ctgcaatgcc
      961 tttaatgtcc gcaggcgcaa gcttcgccgt ggtgcccgca accctgtgcc gtttcgagcc
     1021 attcgtcgtc atcgccgtca aactcttcca cttcgtcaaa ctcgccgcgt tccaccatga
     1081 cgcacaactc ttcaaggctt tccgcgcctt ccacccaaaa acagggaatg cccggcggcg
     1141 tatcgggcgc aagcagtgcc gctacgcctt catgccacgc aatccaatag ccgttgtccg
     1201 tacggacgaa ttgtgcgttt tcgttgaccg actcgccttc cgtaccttcc agcatacgtt
     1261 ccgcaatgtc cggctgaaaa gataaaatct gcataagtgt tcctttatat gatggttttc
     1321 cgtcaaaaca aggcgttata gtggattaaa tttaaaccag tacggcgttg cctcgccttg
     1381 ccgtactatt tgtactgtct gcggcttcgt cgccttatcc tgatttaaat ttaatccact
     1441 atattttaaa acatcgcgcc cgcttgagaa actgccaacc gctttataac aaattcgtct
     1501 ttgcaccaaa ctttccattc tttccgtttt tcggacggca tcgttaaagt agtccttcct
     1561 tttccttatt ttcagcattg ttttatgtta ccgctcaaaa cgcccggcgt actgcccggc
     1621 ttcaaactca gccttggtct gaccgtattg tgcctgtcgc tgcttgtggt cttgccgttt
     1681 gcgatgatgg cggcgaaggc ggcggaaatc ggctggggcg gcttttggaa cacgattgcc
     1741 gagccgaacg tgttggcggc ggtgtggctg agtttgcgga tgtcgtttta tgcgatgctg
     1801 accaatgtcg tgttcggcac gctggtggcg tgggtattgg tgcgttatga attcccgggc
     1861 aagggtctgg cgaacgcgct ggtcgatttg ccgtttgcgc tgccgacggc ggttacgggt
     1921 atcgcgttgg caaccctgta tgcgcccaac ggttggatag gccgtttttt cgagcctttg
     1981 ggcatcaaaa tcgcgtttac gcccgtcggc atttggattg cgctggtcgt cgtcagcctg
     2041 ccctttatcg tccgcgccgt gcagccggtg ttggaggaat tatcgggcga atatgaggaa
     2101 gcggcggcga ctttgggcgc aaaccgcttt acgacgttcc gccgcgtgct gctgccggaa
     2161 atcacgccgg cactcttgac cggcgcggga atgatgttcg cgcgggcaac gggggaatac
     2221 ggctcggtga tttttatcgc gggcaatatt ccgatggttt ctgaaatcct gccgctgatt
     2281 attacgggca agctggaaca gttcgacgtg cagggcgcgt cggcggtggc gttgtttatg
     2341 ctgctggttt cgtttgtgat tctgtttgcg ctgaacgtga tgcagtgggc gttgggcagg
     2401 cgttcgggcg cgaagggttg aggtcgtctg aaatacctgt taccgtcatt cccgcgcagg
     2461 cgggaatcca ttggtgaatt tcggctgcct tatttatttt ctgttttcct gttgccctgc
     2521 ggtggattcc cgcctgcgcg ggaatgacgg tagctagacg tttttattcc cttaatcaat
     2581 aaaaggttgt ctgaaaacga atccgcccca caaaaaacgg tttttcagac ggcatccgaa
     2641 caccttaaaa caaccaaccg gggaacacca ccgccatgaa accctattcc gccaatccca
     2701 acctgaccga accgcgctgg ctgcgcgtgt tgctgattgc cgccgcgctg ggctttctgc
     2761 tgctgatgct ggtcgtgccg ctcgtcgccg tgttttacga agccttaaaa ggcggttggg
     2821 atttgtacct gaaatcctta aacgatcccg aagcgtggtc tgccatcaaa ttgacgctga
     2881 ttaccgcgct gattgtcgtc cccgtcaatg ccgtcttggg cgtggcgatg gcgtggctgc
     2941 tgacccgttt tgattttcgc ggcaagcagt tgctgactac cctgctcgat ttgccgtttt
     3001 ccgtatcgcc cgtggtggcc ggtttaatgt tcgtcttatt gttcggcgcg cacacggcat
     3061 tgggtggctg gctcgaagcg caaggcatac agattatctt cgccatcccc ggcattattc
     3121 tggcgacgct gttcgttact ttcccctttg tcgcacgcga aatcatcccg ctgatgcagg
     3181 ctcagggcga cagcgaagaa caggcggcat tgatactcgg cgcaagcggc tggcagatgt
     3241 tttggcgcgt taccctgccc aacatcaaat gggcgttact ctacggcatc atcctcacca
     3301 acgcccgcgc gatgggcgag ttcggcgcgg tcagcgtggt atcgggacac atacgcggcg
     3361 aaaccaacac cgtcccgctt ttggtcgaaa tcttctacaa cgaatacaac ttcaccggcg
     3421 cattcgccct ctccggcgta ttggcacttt tggcactggc gacgctggcg gtgcagaaca
     3481 tcattaccaa attacaagac aaaaaactcg ccgccgccga aaggaacgca gtatgagtat
     3541 caccatccaa aacttaaaca aacacttcgg caattttcac gcgctgaaaa acatcaacct
     3601 caacgtcccc accggcaaac tcgtttccct gctcggcccg tccggctgcg gcaaaaccac
     3661 gcttttacgc attatcgccg gactggaaaa cgccgacggc ggcaagattc tgtttgatgg
     3721 gcaagacgta accgccaagc acgtgcgcga gcgcaaagtc ggcttcgtgt tccaacacta
     3781 cgcccttttc cgccatatga acgtgtttga caacgttgcc ttcggtttga ccgtattgcc
     3841 caagtccgaa cgcccgtcca aaggacaaat ccgcgccaaa gtcgaagaat tgctgaaact
     3901 cgtacaactc tcgcatttgg caaaatccta tccgcaccaa ctctccggcg ggcaacgcca
     3961 gcgcatcgcc ctcgcccgtg cgcttgcggt cgaaccgaaa ctcctgcttt tggacgaacc
     4021 cttcggcgcg ttggatgcca aagtacgcaa agaattacgc acctggctgc gcgacatcca
     4081 tcacaacctg ggtgtaacca gcattctggt tacgcacgac caagaagaag ccctcgaagt
     4141 ttccgacgaa atcgtcgtga tgaaccacgg caaaatcgaa caaaccggca gcgccgaagc
     4201 tatttaccgc aaacccgaaa atgccttcgt taccgagttc ctcggcgaaa ccgacgcttt
     4261 tgaaggacgc atcgaaaaag gcttctggca ttataacggc ttcgcgtgga aattggacgc
     4321 acaatacaaa tggcaggaac aaaccgccac cggctatatc cgcccgcacg aatggcagat
     4381 cgccgccgaa cacgaaacac cgatgatttg tgccgaaatc gaaaaagtcc acgccgtcgg
     4441 ggcattgacg catattttgg tgaaacacgg caaacaagac gtgcatatca cgctggctgg
     4501 cagcgatgcc gcgcgttacc caatcgccga aggcaaagaa ttgaagctga ttccgaaaca
     4561 ggtttatgtc ttctctcaaa acgaactgat tgaatattcg atttaaccat gaaagcgcaa
     4621 tgccgtctga aaggctttca gacggcattg tgctttcaag cgtcaggcaa gaaacagctt
     4681 gtacgcggca ttttgcgttt cctcgtgata gctgtatccc agactttcca agaaaccgtc
     4741 aaatgcggcg gcatcgtgcg gcggcacatc gataccgacc aaaatccgcc cgtaatccgc
     4801 accgtggttg cggtaatgga agagcgtaat gttccaaccg ccctgcatat ggttcaaaaa
     4861 acgcgccaac gcccccggac gctccggaaa ctcaaaactg accagacgct cgttttctac
     4921 tttgtccgtc cgccctccga ccatatagcg gatatggatt ttggcaatct catcatcggt
     4981 caggtcgaca ttgggcaatc ccgcctcatc caaccggctg ccgataaccg ccaaatcctg
     5041 cgggcctgcc gcttgaagtc cgacaaagat atgcgctttt tcatcgtccc cgtagcggta
     5101 gttgaactcg gtaatattcc tatttcccaa tatattgaca aacttaagga agctgccgcg
     5161 ctcttcgggg atggtaacgg caaaaatacc ttcgttgccc tcgcccaatt cgctccgttc
     5221 cgaaacgtgg cgcaaacggt gaaaattcat attcgcgccg ctggtaacgg caatcagggt
     5281 ttggttttcc gcgccttctc gggcgatata ggctttcaga cctgccaatg ccaatgcacc
     5341 cgccggctcg gtaatgctgc gcgtgtcatc gaaaatatcc ttgaccgcgc cgcaaaccgc
     5401 atcggtatcg actgtaatga tttcatccaa aagttctttg cagaggcgga aggtttcgtt
     5461 tccgacgact ttgaccgcag tgccgtctga aaacagcccg acatctttca aatggacgat
     5521 ttcacccgct tcgaccgact gcttcataca gcaggaatcg ttggtctgaa cgccgataac
     5581 tttgatttcg gggcggacct gcttgataaa tgccgccacg cccgccgcca aaccgccacc
     5641 gcctatcggt acgaatacgg cgcggattgg atcgggatgc tggctgacaa tttccatccc
     5701 taccgtccct tgtcctgcaa tcacatcagg atcgtcaaac ggtgcgatat aggtcagccc
     5761 ttcctgttcc gccagctcca tcgcataatc gtaagcatcg ttgtatgaaa caccgcgcaa
     5821 aaccacctcg ccgccacggc ttttgaccgc atccactttg attttcggcg tagtctccgg
     5881 catgacgata acggcacggc aacccaaacg ctgtgcggac aatgccacgc cttgtgcgtg
     5941 attgcccgcg cttgccgcaa tcacgccgca agcgagcgca tctttcggca acttggacat
     6001 tttgttgtac gcgccgcgta ttttgaacga aaaaaccggc tgcaaatctt cgcgtttcaa
     6061 aaggatgttg tttttcaaac gtacagaaag gctgcgtgcc ggttccaaag gcgtttcgac
     6121 cgcgacatca tagacagatg ccgtcaggat gcggatgagg taattggaat aaggaagggg
     6181 cgtgttcata attcaatatg ggataatcgg tttattaaaa tcgcaaaacc caaaaccata
     6241 cgcccaagac ggcgcgaaag caagaaaaat ccgcccgatc agacacccta agcgtataat
     6301 cggcagactg aaacacgcac acaattagaa tatttcatga cagcacataa aatcctgccc
     6361 gtcctgcttt ccatcatctt aggcgtttct cacgcaacgg ccgcatcgcc cgcgcccaac
     6421 aaaccggcgg tacacgccgc ccccacgttc caaacacccg aaaccctcac agcggcacac
     6481 atcgttatcg accttcaaag caaacagatt ttatccgcca aaaacatcaa tacccctgtc
     6541 gaaccggcgg cactaaccca actgatgacc gcatatctgg ttttcaaaaa catgaaatcg
     6601 ggaaatatcc gatctgaaga aaacttaaaa atacccgaat ccgcatgggc ttcagaagga
     6661 agcagaatgt ttgtacgtcc cggcgatacg gtcagcaccg acaaactctt aaaaggcatg
     6721 attgcactat ccgcaaacga tgccgcccta acccttgccg gccggctggg caacggctcg
     6781 attgaaaatt ttgtgcaaca aatgaacaaa gaagcccgac gcttgggcat gaagaacact
     6841 gtattcaaaa atccgacagg cttgagtaga gaaggacagg tttccaccgc caaagacctc
     6901 gcccagctgt ctgaagcatt gatgcgcgac tttccggaat attacccgct gttttccatc
     6961 aaatctttca aattcaaaaa tatagagcaa aacaaccgca atatcctttt atatagggac
     7021 aacaatgtaa acggtctgaa agccggacac acagaaagcg gcggctacaa ccttgccgtg
     7081 tcatactccg gcaacggcag gcacatcctt gtcatcacat tgggttcgga atcggcggaa
     7141 acacgcgcat cagacaacag caagctgctg aactgggcat tgcaggcctt cgatacgccc
     7201 aaaatatatc cgaaaggcaa aaccgttgcc caaatccaaa tttccggagg cagcaaaaaa
     7261 accgtccgcg caggcttcct caaagaagcc tacatcactc tgccacataa ggaagcgaaa
     7321 atggcagaac aaattctaga aaccatacag ccgattcccg ccccggtaaa aaaggggcag
     7381 attttaggaa aaatcaaaat caggcaaaac ggatacacca ttaccgaaaa agaaattgtc
     7441 gcactggaaa atgtagaaaa aagaagccgg tggcaaaggc tttggatgcg tctgacggga
     7501 cagtaatctg ccgtttcaaa tatcccgttt ttccaacaaa taaagaaatg ccgtctgaaa
     7561 cacggttcag acggcataaa acaacagggc ggtacgtatt gcatacgcgc cgccctgctg
     7621 ctgaaatcaa ttagcgtttt ttaccggtaa cggtggcaac agccagattt tcgttacgtt
     7681 tcaaggaaac gctttctaca ccttcaggca gtttgatgtc ggacagatgc agaatgtcgc
     7741 cggcaaccac ttcggcacaa tccaaatcca agaaagcagg gatattggca ggcaatgcaa
     7801 gcacttcaac agtcgtgttc aacagagata cacggccgcc ttgcagtttg accgcttggg
     7861 aattttcagc gttaacgatg tgcaggggaa cacggatgcg tacaagttga tcggctttca
     7921 cagcttggaa gtcgatgtgt tgaacttcgc ggcggaacgg gtgcatttgg aaatcacgga
     7981 cgataacgtc tttggtttcg ccgttcagag acaatttaat caacgcggta tggaaagatt
     8041 ctttttccaa tgcgtagaat acggttttgt gatccacagc gattgcaaca ggctcttgac
     8101 cttcaccgta cagaatgccg gggatttggc cttcgcgacg caggcggcgg ctcgcaccag
     8161 tgccttgtgc ttcacgaaca gaggcttgaa tttcataagt catgttaaat actccaagtt
     8221 aggtaaaatc gccgtcatcg gccgcgacca gcttaagacg gcttcgggct tatggcagca
     8281 acatactgcc tgtcatcact tcttcattga aaagatatga gacggattct tcattgctga
     8341 tgcggcggac ggtttcggcc aacagaccgg caatcgttac ctgacggata cggtcgcagt
     8401 ttttagccgc ttcagacaaa ggaatggtat cggttacgac cacctggtcg atttcggatg
     8461 aggcgatacg gctgaccgcc tctccggaga atacggcgtg gctggcatat gccaagacac
     8521 gttccgcccc ccgctctttc agagcgacgg cggctttgca cagcgtattt gcagtgtcaa
     8581 tcatatcgtc cacaatcaga caggttctgc cttgaatatc gccgatgatg ttcatgactt
     8641 ccgccacatt ggctttcggg cggcgtttgt cgatgattgc caagtcggca ttcagggatt
     8701 ttgccacggc gcgggcgcgg acgacaccgc cgatgtccgg gctgacgacg gtcagatttt
     8761 caatccgctg ttgtttgatg tcgttcaaca gaatcggggt ggcataaata ttgtccactg
     8821 gaatatcgaa gaaaccttga atctggtcgg catgcaaatc gacagtcaaa acacggtcga
     8881 tccctgccga atacagcata tttgccacca gtttggcaga aatcggaacg cggacggaac
     8941 gcggacggcg gtcttggcgc gcatagccga aatacggaat ggctgtggta atacgacctg
     9001 ccgaagcacg cttcagtgca tccgccatcg tcaggatttc catcaggttg tcattggtcg
     9061 gcgcacaggt cggctgaagg atgaaaacat cgcgcccgcg tacgttttcc aacagttcga
     9121 cggcaacttc gccgtctgaa aacttggata cggaagcatt gcccaaagaa atgtccaaat
     9181 gcctgacaac acgttgtgcc aattcgggat tggcattgcc tgtaaatacc atcaaactgt
     9241 cgtacgcagc catattctca cctgatttta tgtttaactt ccgctcagaa aacacaatgc
     9301 ttccctctgc ttgtaccaag cccgacatta tacctgcaac atccgacaca aacaaaggca
     9361 tttcaatatt tttatttcta tgaaataaaa gcgtgtaagc aggcttacac gcttttattt
     9421 ggctggggag gaaggattcg aaccttcgca tgctggaatc aaaatccagt gtcttaaccg
     9481 cttgacgact ccccaaaaag ggctggctgg ggaggaagga ttcgaacctt cgcatgctgg
     9541 aatcaaaatc cagtgtctta accgcttgac gactccccaa ctcgtttgac ttggctgggg
     9601 aggaaggatt cgaaccttcg catgctggaa tcaaaatcca gtgtcttaac cgcttgacga
     9661 ctccccaaca atgtttatac ggacaacaaa ggatgttttg aaagaccctc tgccaaatat
     9721 gcctcgtaca aatctgaaac ttgtcggtat atattgtatg cgctattcct atcttgacac
     9781 gccgtgaata cacacgcacc agaacctgtc attaaggcaa atccatatcg ggacaattcg
     9841 gaataggctt tccaaacttc agggtattct ttaaatacaa ctgcctgcat gtcatttcta
     9901 aacggttgca ggttttggaa agtcggcatt atgcttgagg cggaatttcg tgtcaagcct
     9961 tcgtgtgtga aaatttttgc agtggaaacg tggacgggcg gtttgacgat gacataccac
    10021 tgtttcggaa tatccatttc gtccagcctg tcgcctatac cccgcgcaaa cgcatttttg
    10081 ccgaaaataa aaaacggtac gtccgccccc agagccgcgc ccgaatcaat gagctgccgc
    10141 tgcgtcagac cgcactgcca ccaacggttc aacaccagca aaacggttgc cgcatccgag
    10201 cttccgccgc ccaaacccgc ccctgtcggg atttttttgt ccagccatat ttccacgccg
    10261 gcggggttgc gcgcatattt ttgcagcaac gatgcggcac ggtagctcaa atcggcttcc
    10321 tgcggcatgc catcaaccgg attgtgcagg atgattttgc cgtcgtccct tagtttcaaa
    10381 tatacggtat cctgcaaatc tatcaggcag aatatgcttt cgatattgtg ataaccgtct
    10441 tcccgctttc cagtaatcct caaatcgaga ttcagttttg caggtgcggg aaacgcctgc
    10501 cgtccgtccg caatattcat ctgtccgcct tatctcgtgc gcgccgcaca gcgttccggg
    10561 gtttcagttt cagacggcat accgatttcg gtgaaaacca gcctgatgtt caaatttccg
    10621 ttattcagtt gcaacgttcg gacttgcccc ccactgtcgg cggttctgcc gacagtccaa
    10681 ccgtattgtt ccaatatgcc gtccggcagg atgcggtaag gcgcgcccgc cacacgcctg
    10741 ccatctgccc agatatgcag atattggatt ggcagtttga aaccgaccag ctgcctgctc
    10801 aattcttccg cactttccgc ctgatagaca tttcctttgc cgtccactgc caatgcgccg
    10861 tccctgtctt gacacaactg cccgagcgta ctgcccaaag gggtattgat attgatggtt
    10921 tccacgggcg gttggtatgt ccaatcgaaa tttgcatacg aacctttccc ttccgctttc
    10981 actgccaacc gcccttccgc cgtgaaactg cgggtgtgtt cggacggctg ccacaggttt
    11041 tcgttatttt gaggcaattg cgcgcaagcg gtcaaaagca ggatgaccga tgcggatacg
    11101 gtatgtttca tcagaatttc cttaacggat gccatcctgc cggccgatgg gttcggcgtg
    11161 ccgtgcaaaa cgcgtgcgaa ctgcgtgcgg tttgcccgaa tgccgcagct tcccggcaaa
    11221 ccttatgccg tctgaaagga tggacctgca ttatttccgg ggtttgcggg aaggttgggg
    11281 caatgcgatg ccgtgacgtt tgagcgtttc ccgccatatt ttcttgtctc ccgtaaggtg
    11341 tgccgcctgc gtccatacgt caaccgcctg atcgcgttcg cccaatgccc acaacacttc
    11401 gcccaaatgg gcggcaactt cgggctcggg gtcgttttca aacgaatacc gcagatacgg
    11461 cagcgcgctt tccgcgtcgc ctttcaggta atacgcccag cctatgctgt cgttgacagc
    11521 ggtatcgtcc gggttgattt ggtatgccgt ctgaagcagg gcgaagcctt cgtccaaacg
    11581 tttggaatcg gaaagcaggc tgtagcccag attattcata atctgagcgt tatcgggtgc
    11641 aagcctgaac gccctttcaa gatctgaaat catttttttc cgcttgccaa gccgatcgta
    11701 aacaactgac cgctgtacca atgcctctgc ctgtaactct gtattactgc cggcaggcgg
    11761 tttttcgata atcttgtcca accccctcaa agcctcccgt ttgtcgggca gcttcgacag
    11821 ggcgaacatc tgtattttgg acaaattgtc tgccgtaaaa taccgcccct gctgttcggg
    11881 aagtttccgc accctgccga tctgccgcaa agccgccctg ccgccgtcca actcgacagc
    11941 cgccgcagcc gccagcacac ctttgtcgaa caggtattcc ggcgcggaca cttttttcaa
    12001 ccactgcctg actttggtgt aatcccttcg gtcggcatat atcatcgccg ccgtcattgc
    12061 cgccctgccc cgctgttccc ccgtccccct gccgtatgcc ttttcggcgt agccgtcgat
    12121 aacggaagca ccttcttttc ggtttgccgc caatatcgct gcctgaatat acaggtctgc
    12181 attcggattg cgttccaaca gcacgttcaa acgcgcatag gcatcatcca gcctgtgcag
    12241 ggaaaccaga ttcataattt ccatttcctg ccagacggcc gaaaggtttt gggtgtctgt
    12301 ctgctcgaaa aagccgtcga gtatttcggg atatttgcgt gcagtcagac gcaacgtcat
    12361 taaagtgggg ggcaatattt ccgtatcgag cttcgccaaa cgctgcaaag ctccgattgc
    12421 cttttccttt tcgcgtccct gtacgctgaa caccacatcg gcaaccgccg cttcgggcag
    12481 atgttcatat ttcaacgccg cgcggcgaac cgctttcgat gctttttgcg ccaacccgtc
    12541 ctgttgcacg gcggcttgtg ccaacaataa aaacaccctg cggttctgtc cttcgtccgc
    12601 ctgagccagc acttcttcca gtccgtccag atgctgattt cctctttccc tcagcacgtt
    12661 ccgcagccac cccgcccgtt tttgcgcctt acccggtata ggctcaatct gccgccattt
    12721 ctgataaatc atttccgcct gttcaaacgc gttcagcgac acggccattt ccaaggcgcg
    12781 ttcggcgact tcgggggatt ttgtgcgttc caacatcagc atataggttg ccagagccgt
    12841 tcccgcctgc cccttttgca aggcggtttc ccctcccagc aacgtaaata tctgattaac
    12901 ccgctcgccc actgccgcaa gccgtgcgcg ttcgtttttg atttcttcct cgctgtaacg
    12961 ctgctgcttt ctgaaaacct ttccgacttc cttcggcggc ttcgcatccg ccgcgccggc
    13021 ggcatacgcc tgcccggcaa gcagggctgc cgcgagcaca gataaaatgg tgaaacgggc
    13081 gggtaacata atcttccttt atccgacagc cgtccgaacc ttcagacggc atataatcag
    13141 gcgtaacttt atcacaagca gaatcgtttg tagatttgcg aaaccccgtt caaaaaaata
    13201 aatgccgtct gaaacgcaaa tccgcttcag acggcattcc cgacgcttgc ggtttaaggg
    13261 agttttattt ccaaattgtc aatcaggcgc gtcgtcccca gacgggcggc ggccaagacc
    13321 accagtttct tatctcccgc ccgcgccact tcgagcgtat cggcgcggcg gatttcgaca
    13381 taatcgacca cccagcccgc agcggtcaaa tggtcggcag cctgccgctc caaacctgca
    13441 taatccaaac tgccctgcgc caaggattcg gcaacagcct ttaattcgcg ggacaggcgc
    13501 ggtgcttcgt cgcgttccgc cgcactcaaa tactggttgc ggctggagag tgccaaaccg
    13561 tcttccgcgc gccccgtatc gacaggcact atttcaacat caaaattcaa atcctcggtc
    13621 aaacctttaa tcacggcaag ctgctgatag tcttttttgc cgaaacaggc aacatccggc
    13681 gcgacaatat tgaacagctt ggacactacc gttgccaccc cgcggaaatg tcccggacga
    13741 aacttgccgc acaactcatt ttgcaggttg ggcggttcga cgttataccg ttgctccacg
    13801 ttcggataga gttctttctc atcgggcgcg aaaacaacgg caacaccctc ggcttccagc
    13861 ttgtccgcat cctgttgcaa agtacgcgga tatttgtcga aatcctcgcc ctgaccgaat
    13921 tgcaggcggt tgacgaatat gctgacaaca acgttgtcgg cgcgtttttt ggcttcgcga
    13981 acgagggcaa gatgcccttc gtgcaggttg cccatggtcg gcacaaatgc cacctttccc
    14041 gcatttttac gccacgcgcg cagttcttga atggtatgta tgatttgcat aacggtaatc
    14101 cttatccttc gggcttcctg cccgacaaaa cgcgccgatt atacgcgccg cacacggcaa
    14161 aacaaaatgc cgtctgaaac ggctttcaga cggcattggc agcaaacctt gttcagtctg
    14221 caaaaatatg ttccgcagca gggaaggttt tggctttaac ttcttcgaca tacgcccgaa
    14281 ccgccgcctg aatgctgctt tgcccatgca taaagttttt gacgaatttc gccgtcttac
    14341 ccgggaaaat gccgagcata tcgtgcatca ccaaaacctg cccgtcgcaa tccgcacccg
    14401 cgccgatgcc gatggtcgga caggaaacag tttcagttac cttttttgcc agttccgccg
    14461 gtacgcactc catcagcacg accgccgccc ccgcatcgtc atgcgccttg gcatcgttaa
    14521 gcaacgcctg cgccttgccg ccgcgcccct gaactttata tccgccgaag gcaaacacgg
    14581 attgcggtgt cagaccgatg tgcgcacaaa ccggaatacc gcgcatttgc aaaaattcag
    14641 tcgtttccgc catccacaca ccgccttcaa gtttaaccat atgcgctcct gccgccatca
    14701 gttcggcggc ggcggcaaac gcctgctcct tactctgctg atatgcacca aacggcaaat
    14761 cactgacaat catcgcattt tttgcaccgc gtgctacaca ttcggtgtga tagcacatat
    14821 cgcgcaggct gacgggcagc gtcgactgcc gcccttgaac cgccataccc aaagagtcgc
    14881 cgaccagcag catttccacg ccggcatcgt ccatcagcgc ggcaaaactg gattcgtaag
    14941 cggtcagcat cgcgattttc tcacctaccg ccttcatttt ttgcagtgtg ttcacagtaa
    15001 tcatcagata ttgttacccc gcccttttca gacggccttt tcagtttgaa acgggctatt
    15061 atagtgaaat gcccgcagcc ctgccaccga ccgtgccgca aatgcaaaac agcccgactg
    15121 ttttacacaa tcgggctgtc aaatctggtg ccggcaccaa gagtcgaact cgggaccccc
    15181 tgattacaag tcaggtgctc taccaactga gctataccgg cttactgaaa tgttttgcaa
    15241 caccatcagc agaaatggtg ccggcaccaa gagtcgaact cgggaccccc tgattacaag
    15301 tcaggtgctc taccaactga gctataccgg caaagaaagc gaattatgca ggcaatgccg
    15361 caccttggca aggaatttat ccgaaagccc cggcaaatcc gaataagtaa tttatttgaa
    15421 aagaaattaa tttgaagcag gacaaccatc ggcattctga taaaatatct gcctttcaaa
    15481 ccgaccgttc acaccgatgg caagacatcc ctaccgccgc ctgcgtcctg caaaatccag
    15541 ctttcccgaa gtcggcattt ccgaagaagg caatatccgt tcgcttcact tgggcagcga
    15601 caccatccaa agctcaatga acctcgacca cccgtccgag ctggtactct cttacagccg
    15661 cgcgatgatg ggctggctgc tgtttaccga cgctcttccg cagcatatca cccaaatcgg
    15721 cttgggcggc ggttcgtttg cacgctggat agacacctac ctgcccgaca cgcgccaaac
    15781 cgccgtggac atcaacccgc aggtcatcgc cattgcccgc agcctgttcg agttgccttt
    15841 cgagggcgag aaatttgaaa ttatcgaagc agacggtgca gaatatatca aagtcttccg
    15901 ccacaacacc gatgtgattt tggtggacgg gttcgacggc gaacaaatca tcgatgcgct
    15961 ggttgaagaa ccgtttttcc gagactgccg aaacgcactc tcttcagacg gcatattcgt
    16021 aaccaactgg tggagcggcg acaaacgcta ccaacgcttc atcgaacggt tgttgagcgt
    16081 ttttgaaggg cgcgtcttgg aacttcctgc cgaaagccac ggcaatgtcg cggtaatggc
    16141 cttccaaagc agccccaaag agcaaaacat agacaaactc aaaaaacgtg ccgacaaact
    16201 gagcaacgca tacggattgg acttccaccg tatgcttgcc ggcctgaaag cgtccaaccc
    16261 caacaacggc aagcatttcc acctttaagc aactatcttc acggctgcat cggaacatgc
    16321 ggaaaatcaa gaggaaatca ttatgctgaa acccgaaacc atacacatat ccggtcctgc
    16381 cggcatttta gaaaccatcc atatcccgtc cgaacaagta ccagcacgcg gtgttgccgt
    16441 catcaatcat cccaaccccc tccagggcgg aacaaacacc aacaaagtta tccaaactgc
    16501 cgccaaagcc ttaagcaaac tcggcttcca ctgctacctg cccaaccttc gcggcgtagg
    16561 cggcagcgaa ggcacacacg attacggacg cggcgaaacg caagactgcc tcgccgtcat
    16621 cgactatgcc cgtgcccaac atcccgaagc ccccgaattt gccttatccg gcttctcctt
    16681 cggcggttat gtcgccacat ttgccgcaca agcgcgcata cccgatttat tgctgctcat
    16741 cggcgcggca gtctgccact ataccggccg ccccgagccg tccgccgttc ccaatgttgc
    16801 caaaacgctg atgatacacg gcgcggaaga cgaagtcgtc gaaatcgaaa aagccctgaa
    16861 atgggcggaa ccgcaagatt tgcccgtcat taccatcgcc ggttccacgc atttctttca
    16921 cggcaaactc atcgtcctgc gcgacaccat cctccgcttc gcgcccgtat gcctgaacgg
    16981 ataaaacccc tttccgacgg catcgataat gtaaaacccg tatcggcggc atctgccgat
    17041 acgggtttgc gttccctctc attataggca aaatccgctg caaaacaccc tttcccgacc
    17101 cgacaaagga tctgcaaacg caatcttttt tgccaatagc ttcaaaggtt tccgataatc
    17161 ctcgctgccc gcttcagacg gcacgggata gagcgcgtca ttcaacagcg gcatacccaa
    17221 acccatcata tgcacgcgca actggtgttt cttgccggta tgcggcgtaa ggcggtaaag
    17281 gctgaattcc cccctgtttt caatcagttc gaccgtcgta tgtgcgtttg gttcgccttc
    17341 cgcctcttgc gtcgtaaaaa atttctcacc ccttaccaaa cgcgaaacca catcaatcgg
    17401 atacggcaaa tccgtccttg tcggcgcaag cgcctcatac gttttccata ccgttttgtt
    17461 ttgaaacatc gtctgataag ccccacgcgt ggcaggattg tgcgacaaca acatcacgcc
    17521 tgccgtatcc ttgtccaagc ggtgcagcgg cgtaatgtcc tcaacattca aatgctgcaa
    17581 ttcaggccgc aaacgcaggc gcgtgagcag ggtttcccgc aaaaacctgc cgctggggat
    17641 gacgggcaga aaatgcggtt tgtccaccac aatcaaatgc tcatcaatat gcaaaatctt
    17701 ttcttcaaac ggaatacgcg gctcgctctc acggctggtt tcccgataat aaaacatcac
    17761 cttacccggc tcgaacaaag tatgttcgtc caacgccgca ccatccgaac cgaccacaaa
    17821 accgctgttc aaccgcctgc gccaatcgtc cgcgcccaca aaaggaaagc ggatgcacag
    17881 aaaatgcagc agcggcagcc cgtaaaactg cttttcatgc ggcagcacca aataactggg
    17941 tttgacaccg ttcaacagcg gaagaggatt attgcgtttt ttcatgcggc ggattgtaac
    18001 cgtttttcac aaacttttca gacggcatat caaaacataa ttgataaaaa caaacatatt
    18061 gttttttatg atttaaaaat ttatttagac aagattatcg gatattcatt attatcagta
    18121 aataagaatt aatatcaata ggagaaatat gaagcgcatc tttttgcccg ccttgcccgc
    18181 catcctgcct ttatccgctt atgccgacct gcccttgacg attgaagaca taatgaccga
    18241 caagggcaaa tggaaactgg aaacttccct tacctacctg aatagcgaaa acagccgcgc
    18301 cgcacttgcc gcaccggttt acattcaaac cggcgcaacc tcgtttatcc ccattccgac
    18361 cgaaattcaa gaaaacggca gcaataccga tatgctcgcc ggcacgctcg gtttgcgcta
    18421 cggactgacc ggcaataccg acatttacgg cagcggcagc tatctgtggc acgaagaacg
    18481 caaactcgac ggcaacggca aaacccgaaa caaacggatg tccgacatat ccgccggcat
    18541 cagccacacc ttcctcaaag acgacaaaaa ccccgcccta atcggctttc ttgaaagcac
    18601 ggtttacgaa aaatcgcgca acaaagcctc gtcgggaaaa tcgtggctca tcggcgccac
    18661 cacctacaaa gccatcgacc ccgtcgtcct ctcattgacc gctgcctacc gtatcaacgg
    18721 cagcaaaacc ctttcaagca acaccaaata caaagcaggc aattactgga tgctgaatcc
    18781 caatatatcc ttcgccgcca acgacagaat cagcctcacg ggcggcatcc aatggctggg
    18841 caagcagccc gaccgtctgg acggcaaaaa agaatccgca agaaacacat ccacctatgc
    18901 ccatttcggc gcaggtttcg gtttcaccaa aaccacggct ttaaacgcat ccgcacgttt
    18961 caacgtttca gggcaaagca gttccgaact gaaatttggc gtacagcata cgttttaagc
    19021 aggttttgat tttccaacct tgtaatccaa aggagttatt atgaaaaaac aaatcaccgc
    19081 agccgtaatg atgctgtcta tgattgcccc cgcaatggca aacggcttgg acaatcagac
    19141 atttgaaaac caagtgttcc acacgcaggc agatgcgccg atacagttgg cggagctttc
    19201 tcaaaaggag atgaaggaaa ctgagggggc tgcattatgg tttgctcccg tgttggcagg
    19261 tggtggcaga tttgcactga caggatttac tcggcatggt ttaaatcagg ctatttctcg
    19321 tggtggtgtg ggagtttcaa ataaagcgat tatgaacact atgcgtaacc ctacaaaaat
    19381 tacaagccaa tcaggaggaa gaacccgttt tacaggagct gatggtggtg ttgttttgaa
    19441 tagtcaaggt aaagtaatta ctacatgggg caaacctcgt taatcaaaaa aagggggctt
    19501 tgcccctttt ataacttaag ggtaatttat gaatattaaa aatgaaatag ttgctttaat
    19561 ttctaaaaaa attgatgggg ggcaatatag ttctttagaa aattttgctt tatccgtact
    19621 aagggaaaaa attataaaaa atactgtttc cagtgatgaa aaattattga ttattaatga
    19681 ttttttatca ggttttcttg agtttgatcc tgagaccggg aaacctgtcg gggagacgct
    19741 taaaattgag caaatgattg atttcttttt agtctaaatc atacatacca gtgaacaagc
    19801 taggcgtata tccggctttt aaatacgatt gtcaggttta tacttgggat aaaatcaaaa
    19861 ataaagttgt ttaa
//
LOCUS       DAXIDM010000031        19351 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000031 DAXIDM010000000
VERSION     DAXIDM010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19351
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.031"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(122..325)
                     /locus_tag="ACFOAE_000902"
     CDS             complement(122..325)
                     /locus_tag="ACFOAE_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HFC6884412.1"
                     /translation="MNGLKADRPSANKANLSIDDVIKQEEIKRISFDMSESLHRELKK
                     YAAENGVTIRVVLNKLVSDLLNK"
     gene            complement(368..775)
                     /locus_tag="ACFOAE_000903"
     CDS             complement(368..775)
                     /locus_tag="ACFOAE_000903"
                     /inference="COORDINATES: protein motif:HMM:NF025001.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HFC6884413.1"
                     /translation="MIDGAPQTADLAISAIKASDLVLIPVQPSPYDIWATADLVNLIK
                     QRIKLIDGNLKAAFLINRTIKGTKIGGEIRAALEEYELPVLSTVIVQRIIYPTSAITG
                     STVLDKEPNGEAAKEIQSLANEIINLINIDNHI"
     gene            complement(788..1012)
                     /locus_tag="ACFOAE_000904"
     CDS             complement(788..1012)
                     /locus_tag="ACFOAE_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC6884414.1"
                     /translation="MKVISVLNQKGGSGKTTVATHLARALQLAGNSILLVDSDPQGSS
                     RDWAAVHEEQPVPVIGIDSPTIDRDLKSVV"
     gene            complement(1359..2366)
                     /locus_tag="ACFOAE_000905"
     CDS             complement(1359..2366)
                     /locus_tag="ACFOAE_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC6884415.1"
                     /translation="MSTFFRQTAQAMIAKHINRFPLLKLDQVIDWQPIEQYLNRQRTR
                     YLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNWLAQDDTLSELLKLINCQLTEKGLKVEKASAAVIDATIIQTAGSEQRQAIE
                     VDEEGQVSGQTTLSKDKNARWTKKNSLYKLGYKQHTRTDAEGYIEKLYITPTNAHECT
                     HLSPLLEGLPKGTTVYADKGYDSKENRQHLKEHRLQNGIMRKACRNRPLTETQTKRNR
                     YLSKTRYVVEQSFGTLHRKFRYARAAYFGLLKVSAQSHLKAMCLNLLKAANRLSAPAA
                     A"
     gene            complement(2538..3707)
                     /gene="metK"
                     /locus_tag="ACFOAE_000906"
     CDS             complement(2538..3707)
                     /gene="metK"
                     /locus_tag="ACFOAE_000906"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFC6884416.1"
                     /translation="MSEYLFTSESVSEGHPDKVADQVSDAILDAILAQDPKARVAAET
                     LVNTGLCVLAGEITTTAQVDYIKVARETIKRIGYNSSELGFDANGCAVGVYYDQQSPD
                     IAQGVNEGEGIDLNQGAGDQGLMFGYACDETPTLMPFAIYYSHRLMQRQSELRKDGRL
                     PWLRPDAKAQLTVVYDSETGKVKRIDTVVLSTQHDPSIAYEELKNAVIEQIIKPVLPS
                     ELLTDETKYLINPTGRFVIGGPQGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVD
                     RSAAYACRYVAKNIVAAGLATQCQIQVSYAIGVAEPTSISIDTFGTGKISEEKLITLV
                     REHFDLRPKGIVQMLDLLRPIYSKSAAYGHFGREEPEFTWERTDKAAALRAAAGL"
     regulatory      complement(3881..3991)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01725"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SAM-I-IV-variant riboswitch; SAM riboswitches
                     modulate the expression of downstream genes in response to
                     levels of S-adenosylmethionine; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01725"
     gene            4044..4940
                     /locus_tag="ACFOAE_000907"
     CDS             4044..4940
                     /locus_tag="ACFOAE_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFC6884417.1"
                     /translation="MFRLQFGLFPPLRTAMHILLTALLKCLSLLPLSCLHTLGNRLGH
                     LAFYLLKEDRARIVANMRQAGMNPDPKTVKAVFAETAKGGLELAPAFFRKPEDIETMF
                     KAVHGWEHVQQALDKHEGLLFITPHIGSYDLGGRYISQQLPFPLTAMYKPPKIKAIDK
                     IMQAGRVRGKGKTAPTSIQGVKQIIKALRSGEATIVLPDHVPSPQEGGEGVWVDFFGK
                     PAYTMTLAAKLAHVKGVKTLFFCCERLPGGQGFDLHIRPVQGELNGDKAHDAAVFNRN
                     AEYWIRRFPTQYLFMYNRYKMP"
     gene            complement(4984..6048)
                     /gene="tsaD"
                     /locus_tag="ACFOAE_000908"
     CDS             complement(4984..6048)
                     /gene="tsaD"
                     /locus_tag="ACFOAE_000908"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFC6884418.1"
                     /translation="MLVLGIESSCDETGVALYDTERGLRAHCLHTQMAMHAEYGGVVP
                     ELASRDHIRRLVPLTEGCLAQAGASYGDIDAVAFTQGPGLGGALLAGSSYANALALAL
                     DKPVIPVHHLEGHLLSPLLAEEKPDFPFVALLVSGGHTQIMAVRGIGDYALLGESVDD
                     AAGEAFDKTAKLLGLPYPGGAKLSELAESGRPEAFVFPRPMIHSDDLQMSFSGLKTAV
                     LTAVEKVRAENGADDIPEQTRNDICRAFQDAVVDVLAAKVKKALLQTGFRTVVVAGGV
                     GANRKLRETFGSMTVQIPTPTGKPKHPSEKVSVFFPPTAYCTDNGAMIAFAGAMHLKT
                     GREAGAFNVRPRWPLSEIVK"
     gene            6055..6180
                     /locus_tag="ACFOAE_000909"
     CDS             6055..6180
                     /locus_tag="ACFOAE_000909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884419.1"
                     /translation="MPLKTEKRILADFGTTAVSQKRNMPSEDRSDGIVAPYQSVP"
     gene            complement(6165..7352)
                     /gene="ccsB"
                     /locus_tag="ACFOAE_000910"
     CDS             complement(6165..7352)
                     /gene="ccsB"
                     /locus_tag="ACFOAE_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="c-type cytochrome biogenesis protein CcsB"
                     /protein_id="HFC6884420.1"
                     /translation="MTEHYKTLPEHELLIQKSLISNLNLWDWVFAVLVFAATVFVQTR
                     SGMHMDIYETVMLWASAGIAVFLGWFFKPMRWFVPLSVLLAYAAVGLYGGNIKSAEIF
                     LLRYFLSSQSAIMWQCAFVFFALFAYISGAVLASVKNVPTNTLLGMGTVFAWVSAVAG
                     FTGLLVRWHESYLLRPDAGHIPVSNLYEVFILFLVITALMYLYYEGKFAIQKLGGFVF
                     GFMAVVVGFVLWYSVSREAHTIQPLIPALQSWWMKIHVPANFIGYGAFCISAMLGIAE
                     LVSLRAEGKGGKLWLPPSALIDEVMYKAIAVGFLFFTIATILGALWAADAWGRYWSWD
                     PKETWAFIVWLNYAVWLHLRLVAGWRGKVLAWWAIIGLFVTAFAFIGVNMFLSGLHSY
                     GTL"
     gene            complement(7345..9297)
                     /locus_tag="ACFOAE_000911"
     CDS             complement(7345..9297)
                     /locus_tag="ACFOAE_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="HFC6884421.1"
                     /translation="MRFAVALLSLLGIASVIGTVLQQNQPQTDYLVKFGPFWAQIFGF
                     LGLYDVYASAWFVVIMMFLVVSTSLCLIRNVPPFWREMKSFREKVKEKSLAAMRHSSL
                     LDVKIAPEVAKRYLEVQGFQGKTVSREGGSVLIAAKKGTMNKWGYIFAHVALIVICLG
                     GLIDSNLLLKLGMLTGRIVPDNQAVYAKDFKPESILSASNLSFRGNVNISEGQSADVV
                     FLNADNGILVQDLPFEVKLKKFHIDFYNTGMPRDFASDIEVTDKATGEKLERTIRVNH
                     PLTLHGITIYQASFADGGSDLTFKAWNLGDASREPVVLKATSIHQFPLEIGKHKYRLE
                     FDQFTSMNVEDMSEGAEREKSLKSTLNDVRAVTQEGKKYTNIGPSIVYRIRDAAGQAV
                     EYKNYMLPVLQEQDYFWITGTRSGLQQQYRWLRIPLDKQLKADTFMALREFLKDGEGR
                     KRLVADATKGAPAEIREQFMLAAENTLNIFAQKGYLGLDEFITSNIPKEQQDKMQGYF
                     YEMLYGVMNAALDETIRRYGLPEWQQDEARNRFLLHSMDAYTGLTEYPAPMLLQLDGF
                     SEVRSSGLQMTRSPGALLVYLGSVLLVLGTVLMFYVREKRAWVLFSDGKIRFAMSSAR
                     SERDLQKEFPKHVESLQRLGKDLNHD"
     gene            complement(9574..10197)
                     /locus_tag="ACFOAE_000912"
     CDS             complement(9574..10197)
                     /locus_tag="ACFOAE_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC6884422.1"
                     /translation="MKRLTLLAFVLAAGAVSASPKADVEKGKQVAATVCAACHAADGN
                     SGIAMYPRLAAQHTAYIYHQTIGIRDGKRTHGSAAVMKPMVMNLSDQDILNVSAFYAK
                     QQPKSGEANPKENPELGAKIYRGGLSDKKVPACMSCHGPSGAGMPGGGSEIQAYPRLG
                     GQHQAYIVEQMNAYKSGQRKNTIMEDIANRMSEEDLKAVANFIQGLR"
     gene            10403..11032
                     /gene="yihA"
                     /locus_tag="ACFOAE_000913"
     CDS             10403..11032
                     /gene="yihA"
                     /locus_tag="ACFOAE_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFC6884423.1"
                     /translation="MNLFQNAKFFTTVNHLKDLPDTPLEIAFVGRSNAGKSSAINTLT
                     NHVRLAYVSKTPGRTQHINFFELQNGNFMVDLPGYGYAQVPEAVRAHWVNLLGDYLQQ
                     RKQLIGLVLIMDARHPLKELDIRMLDFFHTTGRPVHILLSKADKLSKNEQIKTLSQVK
                     KLLKPYSDRQNISVQLFSSLKKQGIDEANRTVGSWFDAADAAASSPEEN"
     gene            complement(11153..13549)
                     /locus_tag="ACFOAE_000914"
     CDS             complement(11153..13549)
                     /locus_tag="ACFOAE_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HFC6884424.1"
                     /translation="MIKKILTTCFGLVFGFCVFGVGLVAIAILVTYPKLPSLDSLQHY
                     QPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWG
                     VARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDK
                     ILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPE
                     RAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRQELYE
                     KYGEDAYTQGFKVYTTVRADHQKVATEALRKALRNFDRGSSYRGAENYIDLSKSEDVE
                     ETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVTLDRRALGFAARAVNNEK
                     MGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFN
                     RAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRY
                     SGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRSSELPASLSMALGTGETT
                     PLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIM
                     YKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPK
                     SMGRVGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLT
                     LDNSGIAPQPSRREKEDDGGAAEGGRQAADDEVRQDMQETPVLPSNTGSKQQQLDSLF
                     "
     gene            13701..14816
                     /gene="pilM"
                     /locus_tag="ACFOAE_000915"
     CDS             13701..14816
                     /gene="pilM"
                     /locus_tag="ACFOAE_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HFC6884425.1"
                     /translation="MRLFKSLKNPKKTDAKLPKKSSGLNNRAAIGIDIDQHSIKMVQL
                     SGRSLNQIQLEKYVIAKLPKNIIQGNKVQNYDQLVTYLQQAYAKLGTSCKNIIASVPQ
                     NLATIEQLTYTDKDAELDLQGFVESSISEVSSISLEEANYDYQVLSQSAAGEAVLAVA
                     SRKDEIEPLIDAFNAAGMKLSALDVDIFGQYNAYALWINHFAPELAAEKVAIFGVYAA
                     QTYALVIQDGKILYKQETSVSEEQLNQLIQRTYQVTEEKAEEIINSPQKPSDYQESVA
                     NYFNQQITQEIQRVLQFYYTTQTADDMTDIKHILLTGEAARQEGIAQTVASQTNADVQ
                     CVHPARYFADNLKTDKQQFELDAPTLTRAFGLAVRGL"
     gene            14819..15418
                     /locus_tag="ACFOAE_000916"
     CDS             14819..15418
                     /locus_tag="ACFOAE_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HFC6884426.1"
                     /translation="MNNLITINLLPYREEMNKRKQQQFKTLMYGAVLTGVAAVAATYL
                     FIDNMINNQSERNTLLETSIAHLDTELSEIQKLKQEKDAFLIKKNKIEELQLKRLQAA
                     KILDSLNEAVPGSTYLTSLDAVTADSYRLSGRTSSDNRVAAMMRAMPNTGIFKQPELL
                     SIKKNNSHQEFTLQATLQPIVKAAESKENPASGNAQEAN"
     gene            15419..16066
                     /locus_tag="ACFOAE_000917"
     CDS             15419..16066
                     /locus_tag="ACFOAE_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HFC6884427.1"
                     /translation="MASKSSKTNLDLNNLHLLNLPARLFIALLAVAAVLGLGYAGLFK
                     SQMESLEEYEAKETELKNTYKQKSIDAASLNNLRDELASIRSAFDIMLKQLPTDAEIP
                     NLVQELHQAGSSNGLRLDSVMPQPPVDDGPIKRLPYSISITGNYEQISQFTRDVGSLS
                     RIITLESLKIAQSPENGGNPDGKSSILNLSAIATTYQAKSVEELAAEAAQNAEQK"
     gene            16084..16629
                     /locus_tag="ACFOAE_000918"
     CDS             16084..16629
                     /locus_tag="ACFOAE_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilP"
                     /protein_id="HFC6884428.1"
                     /translation="MKHYALLISFLALSACSQGSEDLNEWMAQTRREAKAEIIPFQAP
                     TLPVAPVYSPPQLTGPNAFDFRRMETDKKGENAPDTKRIKETLEKFSLENMRYVGILK
                     SGQKVSGFIEAEGYVYTVGVGNYLGQNYGRIESITDDSIVLNELIEDSTGNWVSRKAE
                     LLLNSSDKNTEQAAAPAAEQN"
     gene            16648..18933
                     /gene="pilQ"
                     /locus_tag="ACFOAE_000919"
     CDS             16648..18933
                     /gene="pilQ"
                     /locus_tag="ACFOAE_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009297 - pilus assembly [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus secretin PilQ"
                     /protein_id="HFC6884429.1"
                     /translation="MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKV
                     SFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVLEYADPLLSKISAAQNSSRARLV
                     LNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
                     SVSKPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQTAAPAKQQAAAPAKQT
                     NIDFRKDGKNAGIIELAALGFAGQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKT
                     PVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKKQNLESGGVNNAPKT
                     FTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQ
                     ARNLDMRQQGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRS
                     ILRLDNADTTGNRNTLVSGRGSVLIDPATNTLIVTDTRSVIEKFRKLIDELDVPAQQV
                     MIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGAETKINL
                     PITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIP
                     FTVTSIANGGSSTNTELKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTIL
                     CISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPLLGDIPVIGNLFKTRGKKTDR
                     RELLIFITPRIMGTAGNSLRY"
BASE COUNT         5143 a         5311 c         4390 g         4507 t
ORIGIN      
        1 tttatatgtc aagttttgca atgaaaagac gttctgtttt tggaagaagg tattttgtta
       61 tttttagata aagttggata ttgctttgac attatggtca aatacattct gccgtgtgtt
      121 attatttatt caataaatct gaaacgagtt tattgagcac gacgcgaata gttacaccat
      181 tctcagccgc gtatttcttc aattctctat gcagagattc agacatatca aaactgattc
      241 tcttgatttc ttcttgcttg atcacatcat caatagataa gtttgctttg tttgcactag
      301 gacgatctgc ttttaatccg ttcataatta tttcctacaa tatttaaaaa tttaaaataa
      361 tatttcatta aatatgatta tctatattta tcaaatttat tatctcattc gcaagtgatt
      421 gaatttcctt agctgcttct ccatttggtt ctttatccag tacagtgcta cctgtgatag
      481 cagatgttgg ataaataata cgttgcacaa tcacggttga taaaacaggt aactcatatt
      541 cttctaacgc tgctctaatt tctccgccaa tctttgttcc tttaatagtt cggttaatta
      601 aaaaagcagc ctttaaattt ccatctatga gttttatccg ctgcttgatt aaattaacca
      661 aatcagcggt tgcccaaata tcgtatggcg acggttgaac agggattaaa actaaatcag
      721 aggctttaat cgctgatatg gctaaatcgg ctgtttgtgg tgcgccatca ataataacaa
      781 aatcttttta aacaacgctt tttaaatcac gatcaattgt cgggctgtca ataccaatca
      841 caggaacagg ttgctcttcg tgaacagcag cccagtccct actgcttcct tgtggatcgc
      901 tatcaaccaa taagatgcta tttcctgcta attgcaaggc gcgtgccaag tgagttgcga
      961 ctgtggtttt accacttcca cccttttgat ttaatacgga aataactttc atgttagctc
     1021 ctttgaatat ctacgctcat tatgctttta attaaataat attttaatct attatttaaa
     1081 taaataaaag aatatttaca ttttgtttta aattttagca agaaaagctg ttaaagagat
     1141 tactgtatca aactagactt ttttgagata tgtggcagaa aatgagttga tattgcgtta
     1201 aagtttaaat tgagaccttt gcaaaaaagc ccttccccca acagccgaaa cccaaacaca
     1261 ggttttcgtc tatttccgct cctaattact cctgatttta cccaaatgcc cccttaatcc
     1321 tccccggacg ccccataatc aggcatccgg gctgcctttt aggcggcagc gggcgcactt
     1381 agcctgttgg cggctttcaa caggttcaaa cacatcgctt tcagatggct ttgcgcactc
     1441 actttgagca gcccgaaata ggctgcccgc gcatagcgga atttacggtg cagcgtaccg
     1501 aagctctgtt caaccacata acgggtcttc gacaaatacc ggttgcgttt ggtttgcgtt
     1561 tccgtcagcg gacggttgcg gcaggctttg cgcataatgc cgttctgcaa ccgatgttct
     1621 ttcagatgtt gccggttttc cttgctgtcg tagcctttgt cggcatagac ggtcgtacct
     1681 ttgggcagtc cttccaacaa cggcgacagg tgtgtgcact catgggcatt ggtgggagtg
     1741 atgtacagtt tctcgatata gccttccgca tcggtacggg tatgttgttt gtaaccgagt
     1801 ttgtagaggc tgtttttctt tgtccaacgg gcatttttgt ccttactcag tgtggtttga
     1861 ccgctgactt gtccctcttc atcgacttct atggcctgac gctgttcgct gccggcggtc
     1921 tgaataatgg tggcgtcaat gacggcggcg gatgctttct ctacttttaa gcctttttcg
     1981 gtcagttggc agttaatcag tttgagtaat tcggacaggg tgtcgtcttg cgccagccag
     2041 ttgcggtagc ggcataaggt gctgtaatcg gggatgctca gttcgtcaaa acggcaaaac
     2101 aggttgaaat cgatgcgggt gatgaggctg tgttcgagtt cgggatcgga gaggctgtgc
     2161 cattgtccga gcaggacggc tttgaacatg gatagcaggg gataggcggg acggccgcgg
     2221 tggtctctaa ggtaacgggt tctttgacgg ttcaggtatt gttcgatcgg ctgccaatca
     2281 atcacttggt ccaacttcaa tagcgggaaa cggttgatgt gtttggcaat catggcttgg
     2341 gcggtttgcc ggaagaaggt actcatggaa aatcccctaa atgtcttggt gggaatttag
     2401 gggattttgg ggaattttgc aaaggtctct atctgtactg tctgcggctt cgtcgccttg
     2461 tcctgatttt tgttaatcca ctatataaaa atgccgtctg aactgttcag acggcatttt
     2521 tgattttcaa accggaatta cagccccgct gccgccctca atgcagcagc tttgtcggtg
     2581 cgctcccaag tgaactcagg ttcttcgcgg ccgaaatgtc cgtaagcggc ggatttactg
     2641 taaatcgggc gcaagaggtc gagcatttgg acgatgcctt tggggcgcag gtcgaaatgt
     2701 tcgcgaacta aggtaatcag tttttcttcg ctgattttgc ctgtgccgaa agtatcgatg
     2761 gaaatcgaag tcggttcggc aacgccgatg gcgtaggaaa cttggatttg gcattgggtt
     2821 gccaatcctg cggcgacgat gtttttcgcc acatagcggc aggcgtaggc ggcggaacgg
     2881 tcaaccttgg acgggtcttt gccggaaaac gcgccgccgc cgtgcggagc cgcgccgccg
     2941 taggtatcga cgatgatttt acggccggtc aaaccgcagt cgccttgcgg gccgccgatg
     3001 acgaagcggc cggtcgggtt gatcaggtat ttggtttcgt cggtcagcag ttcagacggc
     3061 aggacgggct tgataatctg ctcgatgacg gcgtttttca gttcttcgta agcgatggac
     3121 ggatcgtgct gggtagagag gacgacggtg tcgatgcgtt ttactttgcc ggtttcgctg
     3181 tcgtaaacca cggtcagttg ggcttttgcg tcagggcgca gccaaggcag gcggccgtct
     3241 ttgcgtaatt cgctttgacg ctgcatcagg cggtggctgt aatagatggc aaacggcatc
     3301 agggtcgggg tttcgtcgca ggcatagccg aacatcaaac cttggtcgcc cgcgccctgg
     3361 ttcaggtcga tgccttcgcc ttcgttcacg ccttgggcga tgtcggggga ttgctggtcg
     3421 tagtacacgc cgaccgcgca gccgttggca tcaaagccca gctcggacga gttgtagccg
     3481 atgcgtttga tggtttcgcg tgcgactttg atgtagtcca cttgggcggt ggtggtgatt
     3541 tcgcccgcca atacgcacaa gcctgtgttg accaaggttt ctgcagcgac acgcgctttg
     3601 gggtcttgcg ccaagatggc atccaaaatc gcatcggaca cttggtcggc aactttgtcc
     3661 ggatggcctt cggataccga ttcggaagta aacagatatt cgctcattgc tattctttca
     3721 ttaaaaacag gctgctgtgt tttcagacgg ccttttattt cggacagcgg aaatcataac
     3781 aaaaactccg ctttttctct atacaagtga gaaacattcg cacttgtctg ctgtttcgga
     3841 atcctgttgc gcgtttctta caggcaaaaa aattcccgca ttaagcgggt ttggattgct
     3901 ctggtgagcc acatcggctt ttcaaccgtc caccttactt ttccttttga aaagcaggtt
     3961 ggcatggaat tcccaactct taatgcagcg cggatggtag cagaaaagcc tttccgccgc
     4021 aatacttccc tttttcagac ggcatgtttc gtttacaatt cgggctgttt ccccctttgc
     4081 gaaccgccat gcacatcctg ttgaccgccc tgctcaaatg cctctccctg ctgccacttt
     4141 cctgtctgca cacgctggga aaccggctcg gacatctggc gttttacctt ttaaaggaag
     4201 accgcgcgcg catcgtcgcc aatatgcgtc aggcaggcat gaatcccgac cccaaaacag
     4261 tcaaagccgt ttttgcggaa acggcaaaag gcggtttgga acttgccccc gcgtttttca
     4321 gaaaaccgga agacatagaa acaatgttca aagcggtaca cggctgggaa catgtgcagc
     4381 aggctttgga caaacacgaa gggctgctat tcatcacgcc gcacatcggc agctacgatt
     4441 tgggcggacg ctacatcagc cagcagcttc cgttcccgct gaccgccatg tacaaaccgc
     4501 cgaaaatcaa agcgatagac aaaatcatgc aggcgggcag ggttcgcggc aaaggaaaaa
     4561 ccgcgcctac cagcatacaa ggggtcaaac aaatcatcaa agccctgcgt tcgggcgaag
     4621 caaccatcgt cctgcccgac cacgtcccct cccctcaaga aggcggggaa ggcgtatggg
     4681 tggatttctt cggcaaacct gcctatacca tgacgctggc ggcaaaattg gcacacgtca
     4741 aaggcgtgaa aaccctgttt ttctgctgcg aacgcctgcc tggcggacaa ggtttcgatt
     4801 tgcacatccg ccccgtccaa ggggaattga acggcgacaa agcccacgat gccgccgtgt
     4861 tcaaccgcaa tgccgaatat tggatacgcc gttttccgac gcagtatctg tttatgtaca
     4921 accgctacaa aatgccgtaa cgaaaataaa aatgccgtct gaacaatttc agacggcatt
     4981 ttgtcatttg acgatttccg acagcggcca gcgcgggcgt acattaaatg caccggcttc
     5041 cctacccgtt ttcaaatgca tcgcgcctgc aaaggcaatc atggcaccgt tgtccgtgca
     5101 gtatgccgtc ggcgggaaaa acacgctgac tttttcggac ggatgtttcg gcttgcctgt
     5161 tggggtcggg atttgcaccg tcatgctgcc gaaagtttca cggagtttgc ggtttgcacc
     5221 gaccccgccg gcgaccacta cggttctgaa ccctgtctgc aacagggctt ttttcacttt
     5281 cgccgccaac acatcgacca ccgcatcttg aaacgcacgg cagatgtcgt tgcgtgtctg
     5341 ctcaggaatg tcatccgccc cgttttccgc gcgcactttc tcaacggcgg tcaatacggc
     5401 ggttttcaaa cctgaaaaac tcatctgcaa atcgtcggaa tgaatcatcg ggcgcggaaa
     5461 aacaaacgct tcgggcctgc ccgattccgc aagttccgac agtttcgcac cgcccggata
     5521 cggcaagccc agcagtttcg ccgttttgtc gaatgcctcg cccgccgcat catcgacgct
     5581 ctcgcccaaa agcgcgtagt cgcctatgcc cctgaccgcc ataatctgcg tatgcccgcc
     5641 cgaaaccagc agcgcgacaa aaggaaagtc gggtttttcc tccgccaaca gcggcgacag
     5701 cagatgtcct tccaaatgat ggacgggaat aacaggcttg tccaacgcta aagccagcgc
     5761 gttggcgtag ctcgaacccg ccagcagcgc accgcccaaa ccgggcccct gcgtaaaggc
     5821 aaccgcgtca atgtcgccat acgatgcgcc cgcctgcgcc aaacagcctt cagtcaacgg
     5881 aacaaggcgg cggatatggt cgcggcttgc caattccggc acaaccccgc cgtattcggc
     5941 gtgcattgcc atttgagtgt gcaggcagtg cgcccgcaat ccacgttccg tatcgtaaag
     6001 cgcaacgccg gtttcgtcgc aagaagactc gattcctaat accaacatgg tctgatgccg
     6061 ttaaaaactg aaaaacgtat tttagcggat ttcggcacga ctgccgtatc ccaaaaacgg
     6121 aacatgccgt ctgaagaccg ttcagacggc atcgtcgcac cgtatcaaag cgttccgtaa
     6181 gaatgcagcc cgctcaaaaa catattcacg ccgataaagg caaatgcggt tacgaacaaa
     6241 ccgataatcg cccaccacgc cagcactttg ccgcgccaac cggcaaccag ccgcaagtgc
     6301 agccaaacgg cgtaattgag ccagacgatg aacgcccacg tctctttcgg atcccaactc
     6361 caatagcgtc cccaagcatc tgccgcccac agcgcaccca aaatggtggc aatggtaaag
     6421 aacagaaagc cgacggcaat cgccttatac atcacctcgt cgatcaatgc cgacggcggc
     6481 agccacagtt ttccgccttt tccttccgca cgcagggaaa ccagttcggc aataccgagc
     6541 atcgcggaaa tgcaaaacgc gccgtaaccg ataaagtttg ccggaacgtg gattttcatc
     6601 caccaagatt gcaatgccgg aatcagcggc tggatggtat gcgcctcgcg ggacacgctg
     6661 taccacaaga caaatccaac cacgaccgcc ataaagccga acacgaagcc gcccaatttc
     6721 tgtatggcga acttaccttc ataataaaga tacatcagcg cggtaatcac caaaaacagg
     6781 atgaacactt catacaggtt ggaaaccgga atatgccccg catcgggacg gagcagatag
     6841 ctttcgtgcc aacgtaccag cagaccggta aagcctgcta cggcagacac ccatgcaaac
     6901 acggttccca tacccaacag cgtgttggtc ggcacatttt ttacgcttgc caaaaccgcg
     6961 cccgaaatat aggcgaacag ggcgaagaag acaaaggcgc actgccacat aatcgccgac
     7021 tggctgctga ggaaataccg caacaggaaa atctctgccg atttgatgtt gccgccatac
     7081 agaccgacgg cggcataggc aagcaatacg cttaaaggaa caaaccagcg catcggtttg
     7141 aaaaaccaac ccaaaaacac ggcaataccg gcacttgccc acaacatgac cgtttcgtaa
     7201 atgtccatat gcataccgga acgggtctgt acgaaaaccg tagccgcaaa aaccagcacg
     7261 gcaaataccc aatcccaaag attcagattg ctgatcaaag acttctgaat cagcagctcg
     7321 tgttccggaa gggttttata gtgttcagtc atgattcaag tccttgccga gccgttgcag
     7381 actctcgacg tgttttggaa attccttctg caaatcccgt tcgctgcggg ccgaagacat
     7441 ggcaaaacgg attttgccgt ctgaaaacaa tacccacgcc cgtttttcgc gcacataaaa
     7501 catcaatacc gtacccaata ccaacagcac cgagccgaga tagaccaaaa gcgcacccgg
     7561 ggaacgggtc atctgcaaac ccgacgaacg cacctcggaa aacccatcaa gttgcagcag
     7621 cataggcgcg ggatattcgg tcaaacccgt gtacgcatcc atactgtgca gcaggaaacg
     7681 gttccgcgct tcatcctgct gccattcggg caagccgtac cggcgtatgg tttcatccaa
     7741 agcagcgttc atcacgccgt aaagcatttc gtagaaatag ccctgcatct tatcctgctg
     7801 ctctttcggg atattggacg taataaattc gtccaatccc aaatagcctt tttgtgcaaa
     7861 gatgttcagc gtgttttccg cagccagcat gaattgttcg cggatttcgg caggtgcgcc
     7921 tttggttgcg tcggcaacca gacgtttgcg cccttcccca tctttcaaaa actcacgcaa
     7981 tgccataaag gtgtccgctt tcaactgctt gtccaagggg atacgcagcc agcggtattg
     8041 ctgctgcaag ccgctgcgcg tgccggtaat ccaaaaataa tcctgttcct gcaaaaccgg
     8101 cagcatatag tttttatatt cgaccgcctg ccctgccgca tcacggatac ggtaaacaat
     8161 ggaagggccg atattggtgt attttttacc ttcctgagta acggcgcgga catcgttcag
     8221 cgtggatttc aggctttttt cccgttccgc gccctcgctc atgtcctcca cattcataga
     8281 agtgaactga tcgaactcaa gacgatattt gtgtttgcca atttccaacg gaaactggtg
     8341 tatggatgtt gccttcaaca cgacaggctc gcgcgaagca tcacccaaat tccacgcctt
     8401 gaatgtcaaa tccgaaccgc cgtcggcaaa actcgcctga taaatcgtga tgccgtgcaa
     8461 ggtcaaagga tggttcacgc ggatggtgcg ctcgagtttc tcaccggttg ccttatccgt
     8521 tacttcaata tcactggcaa aatcgcgcgg catacccgta ttgtaaaaat cgatatggaa
     8581 ttttttcagt ttgacttcaa aaggcaagtc ctgaaccaat atcccgttgt cggcattcag
     8641 gaaaaccaca tccgcactct gcccctcgga aatattgacg ttgcccctaa atgagagatt
     8701 ggacgcactc aaaatacttt cgggcttgaa atccttggca taaaccgcct gattgtccgg
     8761 aacaatccga ccggtcagca tacccagttt caacagcagg ttactgtcta tcaacccgcc
     8821 caggcaaatg acaatcaaag caacatgggc aaagatatag ccccatttgt tcatcgtgcc
     8881 ttttttggcg gcaatcagaa ccgacccgcc ctcacggctg acggtttttc cctgaaaacc
     8941 ctgcacctcc agataacgtt tggcaacctc gggcgcaatt tttacatcca acagcgaaga
     9001 atggcgcatc gccgccagag atttttcttt aaccttttcc cgaaaagact tcatttcgcg
     9061 ccagaacggc ggcacattgc gaatcaggca caaactggta gaaaccacca aaaacatcat
     9121 gataacgaca aaccatgccg aagcatagac gtcatacagt cccagaaaac caaaaatctg
     9181 cgcccaaaaa ggtccgaatt tgaccaaata atccgtctgc ggctggtttt gctgcaacac
     9241 cgtaccgata accgatgcaa tacccagcag actgagcaaa gcgactgcaa agcgcatgga
     9301 gctgaaaaaa gcgaaccacg gacgggaaag aagtggggga gatctacggg atttactcat
     9361 tgtgtgttta ttccgccatc aggaatatgg gaaagcagaa ttgggcaaac agaaaacaac
     9421 gtcccgattc tactgtcttg atgcttttta tttcaagaca atgaagacag cctgcatcga
     9481 ttccaacggt tgcgattgaa aaaacttatc gcagaattgc ctgaagccgt ctgaaaactt
     9541 ttcagacggc ctctaaaaca gactattgcg gaattaacgc aaaccttgga taaagttggc
     9601 gaccgctttc aaatcttctt cagacatacg gtttgcaata tcttccatga tggtattttt
     9661 acgctgaccg gacttgtagg cattcatctg ttcaacaata tatgcctgat gctgaccgcc
     9721 caaacgcgga taagcctgaa tttcgcttcc gcctcccggc atacccgcac cgctcggacc
     9781 gtggcaggac atacacgccg gcactttttt atcgctcaaa ccgccgcgat agattttcgc
     9841 gcccaattcg ggattttcct taggattggc ttcaccggat ttgggctgct gtttggcata
     9901 gaatgcggat acgttcaaaa tatcctgatc gctcaaattc attaccatcg gtttcatcac
     9961 agctgccgaa ccgtgggtgc gtttgccgtc tcggataccg atggtttgat gatagatgta
    10021 agcagtatgc tgtgccgcca aacgcggata catcgcaatg ccgctgttac cgtctgctgc
    10081 atggcaagcc gcacaaaccg ttgcggcaac ctgtttgcct ttttccacgt ctgctttggg
    10141 agaggcggaa accgcaccgg cagccaaaac aaaggccaat aaagtcaatc gtttcatgga
    10201 gtgctcctga ttacagcatt ggataacgca acaatgctct ttttatattc aaatacggga
    10261 tttttgaccc gattaaaacc gatgattctg taaacgtgtt attctatact aaatttacat
    10321 taaattacca ctgtgtttca cataaaacca accgcatatt tttgctgtcg gacaaacggc
    10381 ggcggaaaac aaggatatgc ccatgaacct ttttcaaaac gccaaattct tcacgacggt
    10441 caaccacctt aaagacctgc ccgacacccc tctcgaaatt gcctttgtcg gcaggagcaa
    10501 tgccggaaaa tccagtgcca tcaataccct gaccaaccat gtccgtcttg cctacgtttc
    10561 aaaaacaccc ggacggacgc agcatatcaa cttcttcgag ctgcagaacg gcaattttat
    10621 ggtcgatttg cccggctacg gttatgccca agtccccgaa gcagtacgcg cacattgggt
    10681 caatctgctc ggcgactatc tgcaacagcg caaacagctt atcgggctgg ttttgattat
    10741 ggatgcccgc catcctttaa aagaactcga catccgtatg ctggattttt tccacacgac
    10801 cggcagaccg gttcacatcc tgctgtcaaa agccgacaaa ttatccaaaa acgaacagat
    10861 aaaaaccctg tcccaagtca aaaaactgct caaaccttat tccgacaggc aaaacatcag
    10921 cgtacagctg ttttccagcc tgaaaaaaca aggtattgac gaggccaacc gaactgtcgg
    10981 aagctggttt gacgcagcag atgccgccgc ttcctctcca gaggaaaact gaccccaatt
    11041 atacggaaac cgtatttccc ccacttgacc gaccgcaaac atttaaaaaa ttgccactgc
    11101 caaatctaaa atgccgtctg aaagactttt cagacggcat tttgcggagt ctttaaaaca
    11161 gagaatccaa ctgctgctgt ttggaaccag tattactcgg aagcaccggc gtttcctgca
    11221 tatcttggcg gacttcgtca tccgccgcct gccgtccgcc ttctgccgcg cccccgtcat
    11281 cttctttttc ccgtcgggaa ggttgcggcg caataccgct gttgtccagc gtcaagcccg
    11341 gatcggttac catacgttcc ttcatatagt attcgccatt gctgctgacc acaccttcag
    11401 gcattttcat ccccttgccc tgctttcctt tcaacgcaaa acgcatatag tccacccaaa
    11461 ccggcaccgc aatcgtaccg ccgtagccga cacgccccat actcttaggt ttgtcgaatc
    11521 cgatatatac ggcagtaacc acatcagggt taaaaccgac aaaccacgca tccttattgt
    11581 cattggtcgt acccgtttta ccggcaatat ccgttcttcc caacgcagct gccccccttg
    11641 ccgtaccaac acggaccaca tcctgcataa tcttatacat aatataggca ttgcgcggat
    11701 cgattgcctg aggcgcattt tgcccggcca ccaaaggttg catttgggcg cgcaacctgc
    11761 cgtctctgtc ataaatctta tcgattacgt gcgaagaaac cctatatccg ccgttcgcaa
    11821 atacgctata tgcctccgcc actttcaacg gcgttgtctc gcccgtacct aaagccatag
    11881 acaggcttgc cggcagctcg gacgacctga agccgaaacg ccggatatac tgttgcgcgt
    11941 aaccgacacc gatagacatc aaaatacgga tggaaaccat attcttggaa gccgtcagag
    12001 cctgtctcaa agtaatgtag ccggaatatc tgccgtctga atttttaggt gtccaaaccg
    12061 aaccgttcgg ccctttcccc ggcagggaaa tcggcgcatc gttaaccact gtggacgcgg
    12121 tcatcccctt agataatgcc gccgaataga caaacggctt aaaggtcgaa cccggctgcc
    12181 gcattgcctg aacggcacga ttgaatgttt tgctgtgaaa atcataaccg ccgaccagcg
    12241 cgcgcacagc tccggttttt gcatccagcg aaaccaaagc cccctgcagc aacggctctt
    12301 gaaccaccgc ccaacgcccg ccgttgtttt tgacacggat gaccgcgccc ctgcggatac
    12361 ggtcctcccc cattttttca ttattgaccg cgcgggccgc aaaacccaag gcgcgcctgt
    12421 caagcgtaac ccgcctgccg ccgggcagct gtatgacgac atttttcttt ttagtcacat
    12481 ccaacacaac ggcgggaacc attttatcga cggtatagag tcccgacaga tactggctga
    12541 cagtctcctc gacatcttca ctcttactca aatcgatata gttttccgca ccgcggtagc
    12601 tgctgccgcg atcgaaattc cgtagagcct tgcgcaatgc ctcggttgcc accttctgat
    12661 gatcggcgcg gaccgtggta taaaccttaa aaccctgcgt ataggcatct tcaccgtatt
    12721 tctcatacag ttcctgacgc accatttccg ccacatataa agcactctga tcgattttcc
    12781 gaacaaaccg ctcgtaatgc agttcctcat tcaacgcctg atcgcgctgt tgcacggtaa
    12841 tcatcttctc ctcgagcata ttgttcaaaa tatacttctg gcgcaacttg gcacgttctg
    12901 gattaacaat cggattatag gcagacggag ccttgggcag tcccgcaagc atggcggctt
    12961 ccgccaaagt caaatctcgg acattcttat tgaaatagat ttgcgcggca gatgcaaaac
    13021 cataggcgcg ctgaccgagg taaatctgat tgaaatacaa ctcgaggatt ttgtctttgc
    13081 ttaaagactg ctcgatttta taggcaagca acacctcatt gaatttgcgt gtgaacgttt
    13141 tttcactgct caaataaaaa tttttcgcca cctgctgcgt aatcgtactc gcacccgact
    13201 gcacgctgcc ggacacgaca ttgccgacgg cagcgcgggc aacaccccaa acatccaccc
    13261 cccaatgccg gtaaaagcgt ttgtcctcgg cggcgataac cgcattccgc aacacctctg
    13321 ggaaatcgcc gatttttgta aattcgcgcc gctgctcccc atacataccg atgacttccc
    13381 catccgccga ataaatagtc aacggcattt taggctggta atgctgcaaa gaatccaaag
    13441 acggcagttt cggatacgtt accaaaatag caatggcaac caaacccact ccaaatacac
    13501 aaaacccaaa aaccaaacca aaacaagtcg ttaaaatctt tttaatcata gctgaataat
    13561 aatttaccat tattggtatt aaataaagta aaatagcaac cgatttctac aaagcacggt
    13621 ttcaatgtgc aaagaacaag gaatccatta cggataccga aacggttact cactgtacaa
    13681 ataaagcagg aactttcatc atgcgcttgt ttaaaagctt gaaaaaccct aaaaaaacag
    13741 atgccaagct ccctaaaaaa tcttcgggac tcaataaccg cgcggcaatc ggcatcgata
    13801 tcgaccagca ttccatcaaa atggtccaat tgtcaggacg tagtttaaac caaattcaat
    13861 tggaaaaata cgtcattgcc aaattaccaa agaatatcat tcaaggcaat aaagtccaaa
    13921 attacgatca acttgttaca tatttgcaac aagcctatgc caaactgggt acttcgtgca
    13981 aaaacatcat cgcgtccgtc ccgcaaaatc tggcaaccat cgaacaattg acctacacag
    14041 acaaagatgc agaattagac ctgcaggggt tcgtggagtc ctccatctcc gaagtcagct
    14101 cgatatcgct cgaagaagcc aattacgact atcaggtctt gtcccaatcg gccgccggcg
    14161 aagctgtgtt ggccgtcgca tcgagaaagg atgaaatcga acccctgatt gacgcattca
    14221 acgccgccgg tatgaaatta tccgcgcttg atgtggacat tttcggacaa tacaacgcct
    14281 acgcgctatg gataaaccat ttcgcccccg agcttgcagc cgaaaaagtc gccattttcg
    14341 gcgtatatgc cgcacagacc tacgccttgg tcatccaaga cggaaaaatc ctatacaaac
    14401 aggaaacctc cgtcagcgaa gaacagctca accaactcat ccagcgcacc tatcaggtaa
    14461 cagaagaaaa agcggaagaa atcatcaact ccccgcaaaa accttccgat taccaagaaa
    14521 gcgtggcaaa ctatttcaac cagcagatta cccaagaaat acaaagggtc ttgcagtttt
    14581 attacaccac gcagaccgca gacgatatga ccgacatcaa gcatatcctg ctgaccgggg
    14641 aagcggcgcg ccaggaaggc atcgcccaaa ccgtcgcctc acaaaccaat gcagatgtac
    14701 aatgcgtcca tcccgcgcgt tattttgcgg acaacctcaa aacagacaaa caacaattcg
    14761 aacttgatgc gccgacactg accagggcgt tcggtttggc ggtacgggga ttataattat
    14821 gaacaattta atcacaatca acctcctccc ctacagggaa gagatgaaca agcgcaaaca
    14881 gcagcagttt aaaacgctga tgtacggtgc cgtgctgacg ggcgttgccg ccgttgcggc
    14941 aacctacctg tttatcgaca atatgatcaa taaccagtcg gaaagaaaca cgctgctgga
    15001 aacctccatc gcacacttgg ataccgagct gtcggaaata caaaagctca aacaggaaaa
    15061 agatgccttc ctgattaaga aaaacaaaat cgaggagctc cagctcaaac gcctccaagc
    15121 cgcaaaaatc ctcgacagcc tgaatgaggc cgtccccgga agcacctacc tgacctcgct
    15181 ggatgccgtt accgccgact cttatcggct cagcggcagg acatccagcg acaaccgcgt
    15241 tgccgccatg atgagggcga tgcccaatac cggcatattc aagcaacccg aattgttaag
    15301 catcaagaaa aacaattcgc atcaagaatt tacccttcag gcaacattac aacccatcgt
    15361 aaaggcggcc gaatccaaag agaatccggc ttcgggaaac gcacaggagg caaactgaat
    15421 ggcttctaaa tcatctaaaa ccaacttgga tctcaacaac cttcacctgc tcaaccttcc
    15481 tgccaggctt tttatcgccc tgctggccgt tgccgccgtg ctggggctcg gttatgccgg
    15541 attgttcaaa agccagatgg aatcccttga ggaatacgaa gcaaaagaaa ccgaactgaa
    15601 aaacacctac aaacagaaaa gtatcgacgc ggccagcctg aacaacctga gggacgaact
    15661 tgcctcaatc cgctctgcct tcgatatcat gttgaaacag ctgccgacag atgcagaaat
    15721 tcccaatctg gttcaagagc ttcatcaggc aggttcgagc aacggcctgc gcttggacag
    15781 cgttatgccc caacctcccg tagatgacgg ccccatcaaa agattaccct attccatttc
    15841 cattaccgga aattacgaac agatcagcca atttacccgc gatgtcggca gcctctcccg
    15901 aatcattacc cttgagtcgc tgaaaatcgc ccaatctccg gaaaacggcg gcaatcctga
    15961 cggcaagagc agcatcctga acctcagtgc cattgccacc acctaccaag caaaatccgt
    16021 agaagagctt gccgcagaag cggcacaaaa tgccgagcaa aaataactta cgttagggaa
    16081 accatgaaac actatgcctt actcatcagc tttctggctc tctccgcgtg ttcccaaggt
    16141 tctgaggacc taaacgaatg gatggcacaa acgcgacgcg aagccaaagc agaaatcata
    16201 cctttccaag cacctaccct gccggttgcg ccggtataca gcccgccaca gcttacaggg
    16261 ccgaacgcat tcgacttccg ccgcatggaa accgacaaaa aaggggaaaa tgcccccgac
    16321 accaagcgta ttaaagaaac gctggaaaaa ttcagtttgg aaaatatgcg ttatgtcggc
    16381 attttgaagt ctggacagaa agtctccggc ttcatcgagg ctgaaggtta tgtctacact
    16441 gtcggtgtcg gcaactattt gggacaaaac tacggtagaa tcgaaagcat taccgacgac
    16501 agcatcgtcc tgaacgagct gatagaagac agcacgggca actgggtttc ccgtaaagca
    16561 gaactgctgt tgaattcttc cgacaaaaac accgaacaag cggcagcacc tgccgcagaa
    16621 caaaattaag aagaggatta ctccattatg aataccaaac tgacaaaaat catttccggt
    16681 ctctttgtcg caaccgccgc ctttcagaca gcatcggcag gaaacattac agacatcaaa
    16741 gtttcctccc tgcccaacaa acagaaaatc gtcaaagtca gctttgacaa agagattgtc
    16801 aacccgaccg gcttcgtaac ctcctcaccg gcccgcatcg ccttggactt tgaacaaacc
    16861 ggcatttcca tggatcaaca ggtactcgaa tatgccgatc ccctgttgag caaaatcagt
    16921 gccgcacaaa acagcagccg tgcgcgtctg gttctgaatc tgaacaaacc gggccaatac
    16981 aataccgaag tacgcgggaa caaagtttgg atattcatta acgaatcgga cgataccgtg
    17041 tccgcccccg cacgccccgc cgtaaaagcc gcgcctgccg caccggcaaa acaacaggct
    17101 gccgcaccgt ctaccaagtc cgcagtatcc gtatccaaac cctttacccc ggcaaaacaa
    17161 caggctgccg caccgtttac cgagtccgta gtatccgtat ccgcaccgtt cagcccggca
    17221 aaacaacagg cggcggcatc agcaaaacaa cagacggcag caccagcaaa acaacaggcg
    17281 gcagcaccag caaaacaaac caatatcgat ttccgcaaag acggcaaaaa tgccggcatt
    17341 atcgaattgg ctgcattggg ctttgccggg cagcccgaca tcagccaaca gcacgaccac
    17401 atcatcgtta cgctgaaaaa ccataccctg ccgaccacgc tccaacgcag tttggatgtg
    17461 gcagacttta aaacaccggt tcaaaaggtt acgctgaaac gcctcaataa cgacacccag
    17521 ctgattatca caacagccgg caactgggaa ctcgtcaaca aatccgccgc gcccggatac
    17581 tttaccttcc aagtcctgcc gaaaaaacaa aacctcgagt caggcggcgt gaacaatgcg
    17641 cccaaaacct tcacaggccg gaaaatctcc cttgacttcc aagatgtcga aatccgcacc
    17701 atcctgcaga ttttggcaaa agaatccggg atgaacattg ttgccagcga ctccgtcaac
    17761 ggcaaaatga ccctctccct caaagacgta ccttgggatc aggctttgga tttggttatg
    17821 caggcacgca acctcgatat gcgccaacaa gggaacatcg tcaacatcgc gccccgcgac
    17881 gagctgcttg ccaaagacaa agccttctta caggcggaaa aagacattgc cgatctgggc
    17941 gcgctgtatt cacaaaactt ccaattgaaa tacaaaaatg tggaagaatt ccgcagcatc
    18001 ctgcgtttgg acaatgccga cacaaccgga aaccgcaata cgcttgtcag cggcaggggc
    18061 agcgtgctga tcgatcccgc caccaatacc ctgattgtta ccgatacccg cagcgtcatc
    18121 gaaaaattcc gcaaactgat tgacgaattg gacgtacccg cgcaacaagt gatgattgag
    18181 gcgcgtatcg tcgaagcggc agacggcttc tcgcgcgatt tgggcgttaa attcggcgcg
    18241 acaggcaaga aaaagctgaa aaatgataca agcgcattcg gctggggggt aaactccggc
    18301 ttcggcggcg acgataaatg gggggccgaa accaaaatca acctgccgat taccgctgcc
    18361 gcaaacagca tttcgctggt gcgcgcgatt tcctccggtg ccttgaattt ggaattgtcc
    18421 gcatccgaat cgctttcaaa aaccaaaacg cttgccaatc cgcgcgtgct gacccaaaac
    18481 cgcaaagagg ccaaaatcga atccggttac gaaattcctt tcaccgtaac ctcaatcgcg
    18541 aacggcggca gcagcacgaa cacggaactc aaaaaagccg tcttggggct gaccgttacg
    18601 ccgaacatca cgcccgacgg ccaaatcatt atgaccgtca aaatcaacaa ggactcgcct
    18661 gcgcaatgtg cctccggtaa tcagacgatc ctgtgtattt cgaccaaaaa cctgaatacg
    18721 caggctatgg ttgaaaacgg cggcacattg attgtcggcg gtatttatga agaagacaac
    18781 ggcaatacgc tgaccaaagt ccccctgttg ggcgacatcc ccgttatcgg caacctcttt
    18841 aaaacacgcg ggaaaaaaac cgaccgccgc gaactgctga ttttcattac cccgaggatt
    18901 atgggtacgg ccggcaacag cctgcgctat tgatgcgtca aaataagggc atatgtttta
    18961 cggcatatgc cctttcttta tgctttttgc cgcgaccgaa atgccgtcat tcccgcgcag
    19021 gcagaaatcc aacttgtccg gttccggttg tttttcgtct cgtaactttt gagccgtcat
    19081 tcccgcgcag gcagaaatcc agtccgttca gtttcggtca tttccgataa attcctgttg
    19141 cttttcattt ctggattccc acttttgtgg gaatgacggc ggagaggttt ttgttgtttc
    19201 ggagaagttt ctgcaaccct agaatctcgt tatttccaca aaaaacagaa acccgaaaca
    19261 gcaacttaaa acctcgtcat tcccgcaaaa gcgggaatcc ggtccgttca gtttcggtcg
    19321 tttccgataa attcctgctg cttttcattt c
//
LOCUS       DAXIDM010000032        19303 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000032 DAXIDM010000000
VERSION     DAXIDM010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 19303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19303
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.032"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(327..1220)
                     /locus_tag="ACFOAE_000920"
     CDS             complement(327..1220)
                     /locus_tag="ACFOAE_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFC6884430.1"
                     /translation="MPHPCQTVHTLTARVPKCRLKLNAARRQRYNRPQLFFPNIIMTT
                     TEHDNDDAFLLRYSRHILLDEIGIEGQQKLSAAHILVVGCGGLGAAALPYLAASGVGT
                     LTIADSDTVELHNLQRQVAFDEGDVGKPKAEALADRLKRINHNVDVRTVNEKLDGCRL
                     TGLVQTADIVLDCCDNYATRQAVNRVCVQTKTPLVSGAAVRFEGQLAVYRPDLPDSPC
                     YACLFDGGSASDGICSLFGVFSPLVGIIGSTQAAEALKILLDAGEPSHGRLAVYRALE
                     GGWQYFDLPRNPECPICGAER"
     gene            1263..3965
                     /gene="ppc"
                     /locus_tag="ACFOAE_000921"
     CDS             1263..3965
                     /gene="ppc"
                     /locus_tag="ACFOAE_000921"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HFC6884431.1"
                     /translation="MQLHILNNPKDAALAADAEFLKQSLFNLLHEEASPLVVETVKLL
                     STSDDSAALIEKVLPQLDEQQTHDLTLACGLFAQILNIAEDVHHERRRQIHEEAGRGG
                     AEGSLTETVRRLKAGKADGKSVQRQLDNTSVTAVLTAHPTEVQRQTVLSFNRRIRALL
                     PQRERCTNADALARLRREIDTILLGLWQTSETRRHKLSVNDEINNGVSIFPMSFFEAL
                     PKLYRNMEHDFQMVYPDVCVPNILKIGGWIGGDRDGNPFVSAETLRFAFRRHADAVFR
                     FYRGELDKLYRELPLSIRRVKVNDDVMALAALSPDEELARTEEPYRRAIAYIMARAMG
                     KARALGLGMGCKFGFLEPYASAQEFLDDLKKLQRSLIDNGSRLLAEGRLADLIRSVSV
                     FGFHMMPLDLRQHAGKHADVVAELFQHAGLEDYNSLNEEQKQAVLLRELSHQRPLYSP
                     FITYSDHTRHELAIFNEARKIKDEFGEDAVTQSIISNCEQPSDLLALALLLKESGLLA
                     VENGKPHSRINIVPLFETIEALENACPVMETMFRLDWYDALLESRGNIQEIMLGYSDS
                     NKDGGYVTSSWCLYQAELGLVELFKKYDVRMRLFHGRGGSVGRGGGPSYQAILAQPAG
                     SVAGQIRITEQGEVITAKYADPGNAQRNLETLVAATLEASILPDKKDPDAKLMQALSD
                     VSFKYYRELITHPDFIDYFLQTSPIQEIATLNLGSRPASRKTLARIQDLRAIPWVFSW
                     MQNRLMLPAWYGFGSAVETLCEDKPETLAALREHAQSNPFFQAMLSNMEQVMAKTDIT
                     LAENYAGLSESPEKAAVIFGMIKEEYQRSRKALLDLLQTEELLRDNRSLARSLALRIP
                     YLNALNGLQVAMLKRLRKEPDNPHALLMVHLTINGVAQGLRNTG"
     gene            4088..5077
                     /locus_tag="ACFOAE_000922"
     CDS             4088..5077
                     /locus_tag="ACFOAE_000922"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046167 - glycerol-3-phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFC6884432.1"
                     /translation="MKITVIGAGSWGTALALHFSQHGNRVSLWTRNADQVRQMQEARE
                     NKRGLPGFSFPETLEVCADLADALKDSGLVLIVTSVAGLRSSAELLKQYGAGHLPVLA
                     ACKGFEQDTGLLTFQVLKEVLPDNKKIGVLSGPSFAQELAKQLPCAVVLASENQEWIE
                     ELVPQLNTTVMRLYGSTDVIGVAVGGAVKNVMAIATGLSDGLEYGLNARAALVTRGLA
                     EITRLASAMGAQPKTMMGLAGIGDLILTCTGALSRNRRVGLGLAEGKELHQVLVEIGH
                     VSEGVSTIEEVFNTACKYQIDMPITQTLLQLIRKEMTPQQVVERLMERSARFE"
     gene            5132..5461
                     /locus_tag="ACFOAE_000923"
     CDS             5132..5461
                     /locus_tag="ACFOAE_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884433.1"
                     /translation="MKQNIEKLESSVYTLVQKFETLVSENRRLKETVAELKRAHERQK
                     LEHETAVDELSEALLVQVGKLKEDLQNKIDSLTEENTRYRSLLEQSREKISALAARLP
                     QWQETQQ"
     gene            5472..5777
                     /locus_tag="ACFOAE_000924"
     CDS             5472..5777
                     /locus_tag="ACFOAE_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFC6884434.1"
                     /translation="MNIEQVHIEVMHARLTVNTPAEEKDTLLQAVGMLNGKAEAIREG
                     GRVADSEKIVIMAALNVVHDLLKTSLNGGDLAIGDFARKIADMDNACQKALSRLAQE"
     gene            5783..5962
                     /gene="ssrS"
                     /locus_tag="ACFOAE_000925"
     ncRNA           5783..5962
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACFOAE_000925"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            6140..6571
                     /gene="rplM"
                     /locus_tag="ACFOAE_000926"
     CDS             6140..6571
                     /gene="rplM"
                     /locus_tag="ACFOAE_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFC6884435.1"
                     /translation="MKTFSAKPHEVKREWFVIDAQDKVLGRVAAEVASRLRGKHKPEY
                     TPHVDTGDYIIVINADKLRVTGAKFEDKKYFRHSGFPGGIYERTFREMQEQFPGRALE
                     QAVKGMLPKGPLGYAMIKKLKVYAGAEHAHAAQQPKVLELK"
     gene            6581..6973
                     /gene="rpsI"
                     /locus_tag="ACFOAE_000927"
     CDS             6581..6973
                     /gene="rpsI"
                     /locus_tag="ACFOAE_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019958115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFC6884436.1"
                     /translation="MNGKYYYGTGRRKSSVARVFLIKGTGQIIVNGRPVDEFFARETS
                     RMVVRQPLVLTENAESFDIKVNVVGGGETGQSGAIRHGITRALIDFDAALKPALSQAG
                     FVTRDAREVERKKPGLRKARRAKQFSKR"
     gene            complement(7228..8157)
                     /locus_tag="ACFOAE_000928"
     CDS             complement(7228..8157)
                     /locus_tag="ACFOAE_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC6884437.1"
                     /translation="MDSIIELRHLKTLLALEETGSVSLAAKRVFLTQSALSHQIRMLE
                     NHYGTPLFERKSTPLRFTPVGERLLRLAHELIPQVAVAEWDLARITEGEAGELRIAVE
                     CHTCFDWLMPAMGEFRPMWPQVELDIVSGFQADPVGLLLQHRADLAIVSEAEKQNGIS
                     FQPLFAYEMVGICAPDHPLAAKNVWTAEDFIGETLITYPVPDEMLDLPKKILIPKNIN
                     PPRRHSELTIAIIQLVASRRGIAALPYWTVMPYLEKGYVVHRQITADGLQSKLYAAIR
                     TEDTDKSYLNNFCQIIRERGFADLPGLSELESV"
     gene            8288..9037
                     /locus_tag="ACFOAE_000929"
     CDS             8288..9037
                     /locus_tag="ACFOAE_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFC6884438.1"
                     /translation="MVLRRDFLTWCNETLQTALFKDYAPNGLQVEGREYIGKIVTSVT
                     ASRAAIDFAVEQKADLLLVHHGMFWKNELPTVTGWKKERIAALLRHDINMAGYHLPLD
                     AHPTLGNNAQLADRLGFATEKRFGEQNLLNSGSLKQAKTLGALAAHIETVLQRKPVVI
                     GKPEREIRRVAWCSGGAQGFFQTAIDEGVDLYLTGEISEAQYHLANETGTAFISAGHH
                     ATERYGVRALAESAAEVFGLEVCHFDENNPA"
     gene            9160..9741
                     /gene="petA"
                     /locus_tag="ACFOAE_000930"
     CDS             9160..9741
                     /gene="petA"
                     /locus_tag="ACFOAE_000930"
                     /EC_number="7.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045275 - respiratory chain complex III
                     [Evidence IEA];
                     GO_function: GO:0008121 - ubiquinol-cytochrome-c reductase
                     activity [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_process: GO:0009060 - aerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="HFC6884439.1"
                     /translation="MDNQEINNGRRRFLTLATCGAGGVAALGVATPFVASFFPSEKAK
                     AAGAAVEVDVSKIEAGQLLTAEWQGKPIWVLNRTDQQLKDLKGLNGELTDPNSDAEQQ
                     PEYAKNETRSIKPNILVAIGICTHLGCSPTFRPDIAPADLGADWKGGFFCPCHGSKFD
                     LAGRVYKGVPAPTNLVVPPYKYLSDTTILVGED"
     gene            9760..11109
                     /locus_tag="ACFOAE_000931"
     CDS             9760..11109
                     /locus_tag="ACFOAE_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bc complex cytochrome b subunit"
                     /protein_id="HFC6884440.1"
                     /translation="MANQTNSKAKALLGWVDARFPLSKMWKEHLSEYYAPKNFNFWYF
                     FGSLSMLVLVIQIVSGIFLTMNYKPDGNLNAYHLPAAFTAVEYIMRDVSGGWIIRYMH
                     STGASFFFIVVYLHMFRGLIYGSYKKPRELVWIFGSLIFLALMAEAFMGYLLPWGQMS
                     FWGAQVIINLFSAIPVIGPDLSTWIRGDFNVSDVTLNRFFALHVIAVPLVLLGLVVAH
                     IIALHEVGSNNPDGVEIKKLKDENGVPLDGIPFFPYYVVHDILAVTIFLIVFCAVMFF
                     APEGGGYFLEAPNFDAANALKTPPHIAPVWYFTPFYAILRAIPSFLGTQVWGVIGMGA
                     AVVLIALLPWLDKGEVKSVRYRGPIFKTALVLFIIAFIGLGILGAMVATDTRTLVARI
                     LSFVYFAFFLGMPFYTKLDTNKPVPERVTMSTTKQKIMFFVYVGITVVGAYLFATNI"
     gene            11124..11909
                     /locus_tag="ACFOAE_000932"
     CDS             11124..11909
                     /locus_tag="ACFOAE_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c1"
                     /protein_id="HFC6884441.1"
                     /translation="MKQTLKNWFAALLLAVPMSAAVASGGGHYEKVDIDLRDQVSLQH
                     GAQIFTNYCLSCHSASGMRFNRLKDIGLTDEEIKKNLMFTTDNVGDVMHSAMNPKDAA
                     KWFGAAPPDLTLIARSKGADYLYAYMRGFYKDPTRPSGWNNTVFDKVGMPHPLWEQQG
                     VQAVELDAKGQPVMVKDEHGEMKPKLYWESTGLHSRRLPNGKVIQKEYDAYVRDLVNY
                     LVYMGEPAQLQRKRIGYVVMIFLFAVMLPLAYFLNKEFSKDIH"
     gene            12283..14067
                     /gene="rmuC"
                     /locus_tag="ACFOAE_000933"
     CDS             12283..14067
                     /gene="rmuC"
                     /locus_tag="ACFOAE_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HFC6884442.1"
                     /translation="MELMTVLLPLAALVSGVLFTWLLMKGRFQGEFAGLNAQLAEKAA
                     RCDFVEQAHGKTVSELAVLDGKYRHLQDENYALGNRFSAAEKQIAHLQEKEAESARLK
                     QSYIELQEKAQGLAVENERLATQLGQERKAFADQYALERQIRQRVETDLEESRQTVRD
                     VQNDLSDVGNRFAAAEKQIAHLQEKEAEAERLRQSHIDLQEKAQGLAVENERLATQIE
                     QERLASEEKLSLLGEARKSLSDQFQNLANTILEEKSRRFTEQNREQLHQVLNPLNERI
                     HGFGELVKQTYDKESRERLTLENELKRLQGLNAQLHSEAKALTNALTGTQNKVQGNWG
                     EMILETVLENSGLQKGREYVVQAASVRKEEDGGTRRLQPDVLVNLPDNKQIVIDSKVS
                     LTAYVRYTQAADADTAARELAAHVASIRAHMKGLSLKDYTDLEGVNTLDFVFMFIPVE
                     PAYLLALQNDAGLFQECFDKRIMLVGPSTLLATLRTVANIWRNEQQNQNALAIADEGG
                     KLYDKFVGFVQTLESVGKGIDQAQNSFQTAFKQLAEGRGNLVGRAEKLRLLGVKANKQ
                     LARDLTERANETTALSESLEYVAEDEAV"
     gene            complement(14273..14905)
                     /locus_tag="ACFOAE_000934"
     CDS             complement(14273..14905)
                     /locus_tag="ACFOAE_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFC6884443.1"
                     /translation="MTLRYEILSVTPFRQNCTLIWDDESGEAVLTDVGGDVPFLLQAL
                     ANRKLTLTAIWLTHGHLDHAGGVVEMLKTRKVPVLGPHPDDEFLLQSLPQTTAQYGFP
                     VSPAFAPNHWLEEGETLKVGRYAFQVLHIPGHTPGHVVFYCAEAELLIAGDVLFYETI
                     GRTDFPRGNHADLINNIRNKLFALPETVQVVAGHGRMTSIGHEKRHNPFF"
     gene            14996..15820
                     /locus_tag="ACFOAE_000935"
     CDS             14996..15820
                     /locus_tag="ACFOAE_000935"
                     /EC_number="6.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HFC6884444.1"
                     /translation="MIKKTIGGIIPIFMAVFIPASAGAADLMLAQEYKDQEIAGWAMS
                     EKLDGVRAYWDGKHLISRQGYAFTPPKGFTAQFPPYPLDGELYSGRGQFEQISATVRS
                     VSSDWRGIRLHVFDVPKAQGNLYQRLAVATQWLKTHPNAPITIIPQIKVRDRQHAMDF
                     LKQIEAQGGEGVMLRQPESRYSGGRSSQLLKLKSQYDDECTVTRHYEGKGRNAGRLGA
                     VGCKNRHGEFRIGSGFKDKDRDNPPKIGTLITYRYRGFTRKGTPKFATFVRVRTDR"
     gene            15889..16452
                     /locus_tag="ACFOAE_000936"
     CDS             15889..16452
                     /locus_tag="ACFOAE_000936"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine-guanine phosphoribosyltransferase"
                     /protein_id="HFC6884445.1"
                     /translation="MTDLETKRLETQAMLENADLLFDQGQCRAALQKVADEITRDLGG
                     KYPLLLPVMGGAVVFTGQLLPLLRFPLDFDYVHVSRYGDKLEGGAFNWKRMPDAEQIR
                     GRHVVVLDDILDEGHTMSAIQAKLLEMGAASCRAAVFANKLIDKPKPIRADYVGLDVP
                     NRYVFGYGMDAAGCWRNLGEIYALDGK"
     gene            16534..16971
                     /locus_tag="ACFOAE_000937"
     CDS             16534..16971
                     /locus_tag="ACFOAE_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFC6884446.1"
                     /translation="MIGLLIITHETIGEAYRKLAHHFFPGGLPENVRILGVQPTEDQD
                     DIINNAIAALQEFPDNDGVLIMTDIFGATPCNAARRLVRENKSAILTGLNAPMMVKAV
                     QYSPAAEDLAAFTECVREAAVKGIFAITSAPEDLVCRRSGDAV"
     gene            17040..17309
                     /locus_tag="ACFOAE_000938"
     CDS             17040..17309
                     /locus_tag="ACFOAE_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009174431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HFC6884447.1"
                     /translation="MLKQSIEIINKLGLHARASNKFTQTASQFKSEVWVTKNDSRVNG
                     KSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE"
     gene            17309..19084
                     /gene="ptsP"
                     /locus_tag="ACFOAE_000939"
     CDS             17309..19084
                     /gene="ptsP"
                     /locus_tag="ACFOAE_000939"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFC6884448.1"
                     /translation="MSIVLHGVAAGKGIAVGCAHLIARGTEEVPQYDVAEADTDAEAE
                     RFDAAVKATRKELEQLRSAIPENAPTELGAFISLHLMLLTDVTLSREPVDILREQKIN
                     AEWALKQQSDKLAAQFDNMDDAYLRERKQDMLQVVRRIHNNLIGQGNELEVADNLFDE
                     TVLIANDLSPADTVLFKEQRIAAFVTDAGGPTGHTAILGRSLDIPSVVGLHNARKLIT
                     EGETVIVDGINGVLIIAPDESVLNEYRRRAREYRSHKRDLNKLKKTAAATADGVCIEL
                     VGNIESAEDVKPLHNLGADGIGLFRSEFLYLNRDTMPSEDEQYEVYSAIVKKMKGKSV
                     TIRTVDLGVDKNPRWFGKNSTPNGSLNPALGMTGIRLCLAEPVMFRTQMRAILRAAVH
                     GPVRMMWPMITSVSEVRQCLIHLDTAQRQLAERGDAFGKVGIGCMIEIPSAALTVGSI
                     LKLVDFISVGTNDLIQYILSVDRGDDSVSHLYQPGHPAVLKMLQHVIRTANRMDKDVS
                     VCGEMAGDTAFTRVLLGMGLRRFSMNPNNILPVKNIILHSNVGQLESDIAKVIRCEDE
                     EKSEKLIKQINSVSVEEEADFKGRK"
BASE COUNT         4824 a         5091 c         5234 g         4154 t
ORIGIN      
        1 tttaatcagt cggacaaaat gccttttatc cgatggaacc gttttccgcc cgaacggaaa
       61 taagcggttt tcccctgtaa acagataaaa ccaaccgggt attcatacac agccaaaaaa
      121 aagccgtccg aacccaaagg ggacagacgg ccaaacacat tacggggaaa acgtcttact
      181 caatgagtct gcgaaacaga cattgctaaa acaactgcaa ttataaggta agtttatttt
      241 tttcttgcaa agaaatgtaa atttttaaat ttttaaaacc gttccgccgc atccgtttgg
      301 ataccgtctg aaacggcggc agggttttac cgttccgcgc cgcaaatcgg gcattcgggg
      361 ttgcgcggca ggtcgaaata ttgccagccc ccttccaagg cacggtaaac cgccagcctg
      421 ccgtgcgacg gttcgcccgc atccagcagg attttcagag cctccgccgc ttgggtactg
      481 ccgatgatgc cgaccagcgg cgagaacacg ccgaagaggg aacagatgcc gtctgaagcc
      541 gatccgccgt caaacaggca ggcgtaacac ggcgagtcgg gcaagtcggg acggtacacg
      601 gcaagttgcc cttcaaagcg caccgctgct cctgaaacca gcggtgtttt cgtttgtacg
      661 cagacacggt tgacggcttg gcgcgtggcg tagttgtcgc agcagtctaa aacgatgtcg
      721 gcggtttgaa ccaaaccggt caggcggcag ccgtcgagtt tttcgttgac ggtgcggaca
      781 tcgacgttat ggttgatgcg tttcaggcgg tctgccaagg cttcggcttt gggcttgccg
      841 acatcgccct cgtcaaatgc gacttggcgt tgcaggttgt gcagctcgac cgtgtcggaa
      901 tcggctatgg tcagcgtgcc gacacccgaa gcggcaaggt agggcagtgc ggcggcaccc
      961 aaaccgccgc agccgacgac caaaatatgc gcggcggaaa gtttctgctg cccttcgatg
     1021 ccaatttcgt ccaagaggat gtggcggctg taccgcagca ggaatgcatc gtcgttgtcg
     1081 tgttcggtcg tggtcatgat gatgttcgga aaaaacagtt gtgggcgatt gtaacgctgc
     1141 cgtcgggcgg cgttcaactt cagacggcat ttcgggacac gggcggttaa agtgtgaacg
     1201 gtttggcacg gatgcggcat ttgaggtaca tttacagtat ttacggcaat gagagaaaaa
     1261 tcatgcaact gcatattctg aacaatccaa aggacgcggc tttggcggcg gacgcggaat
     1321 ttctgaaaca atccctgttc aacctcctgc acgaagaagc ctcgccattg gttgtcgaaa
     1381 cggtcaaact cttgtccact tccgacgaca gcgcggcatt gattgaaaaa gtattgccgc
     1441 aattggacga acaacaaacc cacgatttaa ccttggcctg cggcctgttc gcccagattt
     1501 tgaatatcgc cgaagacgtg caccacgaac gccgccgcca aatccacgaa gaagccggac
     1561 gcggcggcgc ggaaggcagc ctgacggaaa ccgtccgcag gctcaaagcg gggaaagccg
     1621 acggcaaatc ggtgcagcgg cagttggaca atacgtccgt taccgccgtt ttgaccgcgc
     1681 acccgaccga agtgcaacgc caaaccgtct taagcttcaa ccgccgcatc cgcgcactgt
     1741 tgccgcaacg cgaacgctgc accaatgccg acgcgctggc acggctgcgc cgcgaaatcg
     1801 acactatcct gctgggcttg tggcagacca gcgaaacgcg ccgccacaaa ctcagcgtca
     1861 acgacgaaat caacaacggc gtgtccatct tcccgatgag ctttttcgaa gccctgccca
     1921 agctctaccg caatatggaa cacgactttc agatggtcta tcccgatgtc tgcgttccga
     1981 atatcctcaa aatcggcggc tggatcggtg gcgaccgcga cggcaatccg ttcgtttctg
     2041 ccgaaacctt gcgttttgcc ttccgccgcc acgccgatgc cgtgttccgt ttttaccgtg
     2101 gcgaactcga caaactttac cgcgaactgc cgctctccat ccgccgcgtc aaagtcaacg
     2161 acgacgtaat ggcactggca gccctctcgc ctgacgaaga acttgcccgc acggaagaac
     2221 cctaccgccg cgccattgct tacatcatgg cgcgcgctat gggcaaagcg cgcgcgctcg
     2281 gtttgggcat gggctgcaaa ttcggctttc tcgagccgta tgcttcggca caagaatttc
     2341 tcgatgattt gaaaaaattg caacgttccc ttatcgacaa cggcagccgc ctgcttgccg
     2401 aaggccgttt ggcagacctc atccgttccg tgtccgtgtt cggcttccac atgatgccgc
     2461 tcgacctgcg ccaacacgca ggcaaacacg ccgatgtggt tgccgagctt ttccaacacg
     2521 caggcttgga agactacaac agcctgaacg aagaacaaaa acaagccgtc ctgttgcgag
     2581 aattgagcca tcaacgtccg ctgtacagcc cgttcatcac atacagcgac catacccgcc
     2641 acgaactggc aattttcaac gaagcgcgca aaatcaaaga cgaatttggc gaagatgccg
     2701 taacacaaag cattatttcc aactgcgaac aacccagcga cctgctcgcc ttggcattgc
     2761 tgctgaaaga aagcggcctg ttggcggtgg aaaacggcaa accgcacagc cgcatcaata
     2821 tcgtgccgct gtttgaaacc atcgaagcac tcgaaaacgc ctgtccggtc atggaaacca
     2881 tgttccgcct cgattggtac gatgccctgc tcgaaagccg cggcaacatc caagaaatta
     2941 tgctcggcta ctccgactcc aacaaagacg gcggctatgt taccagctca tggtgtctgt
     3001 atcaggcgga attgggcttg gtcgaactct tcaaaaaata cgatgtccgc atgcgcctgt
     3061 tccacggtcg cggcggcagc gtcggacgcg gcggcggtcc gtcttaccaa gccattctcg
     3121 cccaaccggc gggcagcgtt gccggacaaa tccgcattac cgaacaaggc gaagtcatta
     3181 ccgccaaata cgccgacccc ggcaatgccc aacgcaactt ggaaaccttg gttgccgcga
     3241 ctttggaagc cagcatcctg ccggataaaa aagaccctga tgccaaactg atgcaggcat
     3301 tgtcggacgt atcgttcaaa tactaccgcg aactgattac ccaccccgac ttcatcgact
     3361 acttcctgca aaccagcccg attcaggaaa tcgccaccct caacctcggc agccgtcccg
     3421 ccagccgcaa aaccttggca cggattcagg acttgcgcgc gattccgtgg gtattttcct
     3481 ggatgcaaaa ccgcctcatg ctgccggctt ggtacggttt cggcagcgcg gtggaaacct
     3541 tgtgcgaaga caaacccgaa acgctcgccg ccctgcgcga acacgcccaa agcaacccgt
     3601 tcttccaagc catgctttcc aatatggagc aagtgatggc gaaaaccgac atcaccctcg
     3661 cggaaaacta tgccggcttg agcgaatcgc cggaaaaagc cgccgtcatc ttcggcatga
     3721 ttaaggaaga ataccaacgc agccgcaaag ccctgctcga cctgctgcaa accgaagaac
     3781 ttttacgcga caaccgcagc ctcgcccgtt cgcttgcctt gaggattccc tacctgaacg
     3841 cgctcaacgg cctgcaggtc gccatgctca aacgcctgcg taaagaaccc gacaatccgc
     3901 acgcgctgct gatggttcac ctgaccatca acggcgtggc gcaaggtttg cgcaatacag
     3961 gctgattgtg ccgcatcggg gcaaaatgcc gtctgaacac ctttcagacg gcatttccct
     4021 gaccgcactt gcagagaaac accgattgtt ttaaagtgaa cggcagtgat atgttgaaag
     4081 acgaccaatg aaaattaccg ttatcggcgc aggttcgtgg ggtacggcgc tcgccctgca
     4141 cttttcccaa cacggcaacc gcgtatccct gtggacgcgc aacgcagacc aagtccgcca
     4201 aatgcaggaa gcgcgtgaaa acaaacgcgg actgcccggc ttttcctttc ccgaaacctt
     4261 ggaagtgtgt gcggatttgg cagacgcgct caaagacagc ggacttgtcc ttatcgtaac
     4321 ctccgttgcc ggattgagaa gcagcgcaga gctgctcaaa cagtacggcg cgggacacct
     4381 ccccgtcctc gccgcctgca aaggattcga gcaggataca gggctgctga cctttcaagt
     4441 attgaaagaa gtattgcccg acaataagaa aatcggcgta ctctccggcc cgagttttgc
     4501 acaggaactc gccaaacaac tgccctgtgc cgtcgtcctc gcctccgaaa accaagagtg
     4561 gattgaagaa ctcgtaccgc agctcaacac gactgtcatg aggctttacg gcagtaccga
     4621 cgttatcggc gtggcggttg gcggcgcggt aaaaaatgtt atggcgattg ccaccggatt
     4681 gtccgatggc ctagagtacg ggcttaacgc ccgtgccgca ctggttacgc gcggattagc
     4741 tgaaattacc cgccttgcct ccgcaatggg cgcacagccc aaaaccatga tggggctggc
     4801 aggcatcggc gacctcatct tgacctgcac tggcgcactc tcacgcaacc gccgcgtcgg
     4861 cttgggtttg gcagaaggca aggaactgca tcaggtgctg gtcgaaatcg gacacgtttc
     4921 cgaaggggtc agcacgatag aagaagtctt caatactgcc tgtaagtacc aaatcgatat
     4981 gccgattacc caaaccctgc tgcaactcat ccgtaaggaa atgacccctc agcaggtcgt
     5041 cgaaagactg atggaacgca gcgcgcgttt cgaataaaca acagacagat gccgtctgaa
     5101 gccttcagac ggcatacgga caggtaaggt tatgaaacaa aatatcgaaa aactcgaaag
     5161 cagcgtttat acgctggtac aaaaattcga aaccctcgtc agcgaaaacc gccgcctcaa
     5221 agaaaccgtc gccgaactca aacgggcgca cgagcggcaa aaactcgaac acgaaaccgc
     5281 cgtcgacgaa ctcagcgaag ccctgctcgt ccaagtcggc aaactcaaag aagacctgca
     5341 aaacaaaatc gacagcctga cagaagaaaa tacacgatac cgcagcctgc tcgaacagag
     5401 cagggaaaaa atcagcgcac tggcagcgcg cctcccccaa tggcaggaaa cgcagcaata
     5461 aggattaaag gatgaacatc gaacaagtcc acatcgaagt catgcacgcc cggctgaccg
     5521 tcaacacgcc ggcagaagaa aaagacacac tgttgcaggc agtcggaatg ctcaacggca
     5581 aagccgaagc catccgcgaa ggcggacgcg tcgcggacag cgaaaaaatc gtcattatgg
     5641 ccgcgctcaa cgtcgtccac gacctgttga aaacctctct gaacggcggc gatttggcaa
     5701 tcggcgattt tgcgcgtaaa atagccgata tggacaacgc ctgccaaaaa gcactatccc
     5761 gcttggcgca ggaataaccc ctttttccct gcggtgtccg cgaaggcata tattcctttg
     5821 aaccaataag ttcgcttaag gttgccggga gcagtagtgg gcgcgagcgt ccttttgcgg
     5881 acgcacccga aactacccga ggcagccgcc ttgtcagcaa ggttcaagcg gattcggccg
     5941 aaacggctct cgcggggatt cccattcaaa accgcatcgc aacgatgcgg tttttcacat
     6001 tggccgccgc cccgcccgaa aaagcagtat gcagtctgcc gaaatccgga aaatccttcc
     6061 gtaacgcggt aatgcgattg acaaaatcga atcctgtctt taaaatttac aactttctat
     6121 atctatctgg atttccacta tgaaaacctt ttcagcgaaa ccccacgagg tgaagcgcga
     6181 atggttcgtc atcgatgccc aagacaaagt cttgggtcgc gttgcggccg aagtcgccag
     6241 ccgtctgcgt ggcaaacaca aacctgaata caccccccac gtcgataccg gcgattacat
     6301 cattgttatc aatgcggaca aactgcgtgt aaccggtgcc aaattcgaag ataaaaaata
     6361 cttccgccat tccggtttcc caggcggtat ctacgaacgc actttccgcg aaatgcaaga
     6421 gcaattcccg ggccgcgctt tggaacaagc tgtaaaaggt atgctgccca aaggtccttt
     6481 gggttacgcc atgattaaaa aactgaaagt gtatgcgggt gcggaacacg cccatgctgc
     6541 gcaacaaccc aaagttttgg aactgaaata aggacgcgac atgaacggta aatactacta
     6601 cggcacaggc cgccgcaaaa gttcagtggc tcgtgtattc ctgattaaag gtacaggtca
     6661 aatcatcgta aacggccgtc ccgttgacga attcttcgca cgcgaaacca gccgaatggt
     6721 tgttcgccaa cccttggttc tgactgaaaa cgccgaatct ttcgacatca aagtcaatgt
     6781 tgttggcggc ggcgaaaccg gccagtccgg cgcaatccgc cacggcatta cccgtgccct
     6841 gatcgacttc gatgccgcgt tgaaacccgc cttgtctcaa gctggttttg ttacccgcga
     6901 tgcccgcgaa gttgaacgta aaaaaccggg tctgcgcaaa gcacgccgtg caaaacaatt
     6961 ctccaaacgt taatgttgga aattcaaaaa accctgctta tcgcagggtt ttttatttgt
     7021 agtagacggt ttcccattgg caatctaaag attacagatt gggcaaaaat caaaaacagt
     7081 atagtggatt aacaaaaatc aggacaaggc gacgaagccg cagacagtac aaatagtacg
     7141 gcaaggcgag gcaacgctgt actggttttt gttaatccac tatacatgaa aaaatagaaa
     7201 aactgccggg tatggttgaa taaggggtca gaccgattcc agttcgctca gtccgggcaa
     7261 atctgcaaaa ccgcgttcgc gtatgatttg gcaaaaattg ttcagatagc tcttgtccgt
     7321 atcttcggta cggatggcgg catacagttt gctttgcagt ccgtcggcag taatttggcg
     7381 gtggacgaca tagccttttt caaggtaggg catgactgtc caataaggaa gggcggcaat
     7441 gccacgtctg ctggcaacca gttggataat ggcgatggtc agttcgctgt gtcggcgcgg
     7501 cgggttgatg tttttcggaa tcaggatttt tttgggcaaa tccagcatct cgtcgggaac
     7561 gggataagta atcagggttt ccccgataaa gtcttccgcc gtccaaacgt ttttggcggc
     7621 aagcggatgg tctggtgcgc aaatgccgac catttcgtag gcaaacagcg gttggaaaga
     7681 aataccgttt tgtttttccg cttcggaaac aatggcaagg tcggcacggt gttgcagcag
     7741 cagtccgacg ggatccgctt ggaatcccga tacgatatcc aattcgactt ggggccacat
     7801 cgggcggaat tcgcccatgg cgggcatcag ccagtcgaaa caggtatggc attcgacggc
     7861 aatccgcagc tctcccgcct ctccttccgt gattcgcgct aaatcccatt ctgcaacagc
     7921 aacttgaggt atcagttcgt gggcgaggcg cagcagcctt tcgcccaccg gggtaaagcg
     7981 caagggcgtg gatttgcgtt cgaacagcgg cgtgccgtag tggttttcaa gcatacggat
     8041 ctggtgggaa agggcggatt gggtaaggaa aacccgtttg gcggcaaggg agacgctgcc
     8101 ggtttcttca agtgccagca gggttttgag gtggcgcaat tcgataatgg aatccatggg
     8161 gcttcagacg gcatattgaa ccggcgcata ttaaaataat tcatatgcgg gtgcaaatcg
     8221 gaaaaatgtg aattccggac attttgcgat tagaatgccc gcttgtttaa agcgattagg
     8281 aaaaaagatg gtattgcgca gggattttct gacttggtgt aatgaaacat tgcagacagc
     8341 gttgtttaaa gattacgccc ctaacggttt gcaggttgaa gggagggaat atatcgggaa
     8401 aatcgttacg tcagtaacgg caagcagggc agcgattgat tttgctgtgg agcagaaggc
     8461 agatttgctt ttggtacatc acggtatgtt ttggaaaaac gagttgccga ccgttactgg
     8521 ttggaaaaaa gaacggattg ccgcactgtt acggcacgac atcaatatgg caggctacca
     8581 tctgccccta gatgcacatc ccacactggg caacaatgcc caactcgccg acagattggg
     8641 ttttgcgaca gaaaaacggt tcggcgaaca aaacctgctc aactcgggca gcctgaaaca
     8701 agccaagaca ctcggcgcat tggcggcgca tattgaaaca gttttgcaac gtaagcctgt
     8761 cgtcatcggc aaacccgaac gcgaaatccg acgggttgca tggtgcagcg gcggggcgca
     8821 ggggtttttt cagacggcaa tagacgaagg tgtcgatctg tatttgacgg gggaaatctc
     8881 tgaagcccaa taccaccttg ccaatgaaac gggtacggct ttcatttcgg cagggcatca
     8941 cgcgacggaa cgttacggcg tacgcgcgct ggcagaatcg gcggcagagg ttttcgggtt
     9001 ggaagtgtgc cattttgacg aaaacaatcc ggcttgagtc ttgagaaata tcataaaact
     9061 ttaccttatt ttaaataatg ctttgagtat cactgcaaac tgggtaaaat tgcaacgttt
     9121 aatggctcgg tattcccaaa atattaggac gactgaataa tggataatca agaaatcaac
     9181 aacggccgcc gccgtttcct gacactcgcg acctgcggcg cgggcggagt ggcagcattg
     9241 ggtgtggcaa cgccgtttgt ggccagtttt ttcccttcgg aaaaagccaa ggccgccggt
     9301 gctgccgtcg aggtggatgt cagtaaaatc gaagcgggtc agctgctgac cgccgagtgg
     9361 caaggcaaac cgatttgggt gctcaaccgt acagatcagc agcttaaaga cctgaaaggc
     9421 ctgaacggcg aacttaccga tcccaattcc gatgcggaac agcagccgga gtatgcgaaa
     9481 aacgagaccc gttcgattaa gccgaacatc cttgtcgcca tcggtatctg cacccatttg
     9541 ggctgctcgc ccaccttccg tcccgacatt gcccccgccg atttgggtgc agactggaaa
     9601 ggcggcttct tctgcccctg ccacggttcg aaattcgact tggccggccg cgtatataaa
     9661 ggtgttcctg ccccgaccaa cctggttgtc ccgccatata aatacttgag cgacacaact
     9721 atcttggtgg gcgaagacta agaataagga acgataatta tggcaaacca aaccaatagc
     9781 aaagcaaaag cattgttagg ctgggtagat gcccgttttc cattaagtaa aatgtggaaa
     9841 gagcatctgt ctgaatacta tgcgcctaaa aacttcaact tctggtattt cttcggctca
     9901 ttgtctatgc tggtgctggt gattcaaatc gtcagcggta ttttcctgac catgaactac
     9961 aaaccggacg gcaaccttaa cgcctaccat ctgcctgctg cctttaccgc agtagagtac
    10021 atcatgcgcg acgtgtccgg cggctggatt atccgctata tgcactctac cggcgcatct
    10081 ttcttcttca tcgtcgttta tctgcacatg ttccgtggtc tgatttacgg ttcgtacaaa
    10141 aaaccgcgcg aattggtgtg gattttcggt tccctgattt tcttggcatt gatggcagaa
    10201 gcctttatgg gttacctgtt gccttggggt caaatgtcct tctggggtgc gcaggtaatt
    10261 attaacctgt tctccgccat ccctgttatc ggtcctgatt tgtccacttg gatccgcggt
    10321 gacttcaacg tttccgatgt tactttgaac cgattcttcg ccctgcacgt tatcgctgta
    10381 cctttggtat tgctcggctt ggttgtggct catatcattg ccttgcatga agtgggttcc
    10441 aacaaccctg acggtgtaga aatcaaaaag ctgaaagatg aaaacggtgt ccctctagat
    10501 ggcatacctt tttttccgta ttatgttgtg catgatatat tggcagtaac gatattcttg
    10561 attgtcttct gtgccgtgat gttctttgca ccagaaggcg gcggctactt cctcgaagcg
    10621 ccgaacttcg atgctgcgaa tgcgctgaaa acacctccgc acattgcacc ggtatggtac
    10681 ttcactccgt tctacgccat tttgcgtgcg attccctcgt tcttgggaac acaggtatgg
    10741 ggtgtaatcg gtatgggtgc ggcagttgta ctgattgccc tgttgccttg gttggataaa
    10801 ggcgaggtta aatctgtccg ctatcgcggc ccaatcttca aaaccgcatt ggttctgttc
    10861 atcattgcct tcatcggttt gggtattttg ggtgcaatgg tagcaactga tactcgtact
    10921 ttggttgcac gtatcctgtc tttcgtctac tttgcattct tcctgggtat gccgttctat
    10981 accaaactgg ataccaacaa accagttcct gaacgcgtaa ccatgagcac tactaaacaa
    11041 aaaattatgt tctttgttta cgtcggtatt accgttgttg gtgcttactt gtttgcaacc
    11101 aatatctgat gagggcagcg aaaatgaaac aaactctgaa aaactggttt gctgccttat
    11161 tgctggcagt gcctatgagt gcagccgtcg ccagcggcgg cggacactac gaaaaagtcg
    11221 atatcgacct gcgtgaccaa gtcagcctgc agcacggtgc gcaaatcttt acaaactact
    11281 gtttgtcttg ccactctgca agcggtatgc gcttcaaccg tctgaaagac atcggtttga
    11341 ctgacgaaga aatcaagaaa aacctgatgt ttaccaccga taatgtcggc gatgtcatgc
    11401 attcggcgat gaacccgaaa gatgcggcaa aatggtttgg tgctgctccg cccgatttga
    11461 cgttgattgc gcgttccaaa ggtgcagact acctttacgc ctatatgcgc ggcttctata
    11521 aagatccgac ccgtccgagc ggctggaaca atactgtatt cgataaagtc ggtatgcccc
    11581 acccgttgtg ggagcaacaa ggtgttcaag ccgttgagtt ggatgccaaa ggtcagccgg
    11641 ttatggtaaa agacgaacac ggcgagatga agcctaagct gtattgggaa tctaccggtt
    11701 tgcacagccg ccgcctgcct aacggcaaag tgatccaaaa agagtacgac gcatatgtac
    11761 gcgatttggt caattacctt gtgtacatgg gcgaacctgc acaactgcaa cgcaaacgta
    11821 taggctatgt cgtgatgatt ttcctatttg cggttatgct gcctttggct tacttcctaa
    11881 ataaagaatt ttctaaagat attcattaat cattaaaaaa gaatattgga aagacgtaca
    11941 ctaagcgttt ggaacaaaag ggcaaatcct ttagggtttg cccttttttc attttgcctg
    12001 ccgtttgaaa agcctgaatc cgtatgccgt ctgaacatag ctgcaacatt tcagacggca
    12061 tcattctaaa aatgtcagac atcgggaact taatcagggt ttgtggcaga ttgatattga
    12121 attaggaaaa ggtctgaaac cgcaagcagc atggtaaggc gatgtcgaac aggtttaaag
    12181 ccaatccgct atattttttg gagctatgtc gaacaaacag gtagaatcgg aataagcggc
    12241 ggttttgtcc ggtgtgaaaa tgtttgaata ttaggatgat tgatggaact gatgactgtt
    12301 ttgctgcctt tggcggcgtt ggtgtcgggc gtgttgttta catggttgct gatgaagggc
    12361 aggtttcagg gcgagtttgc cggtttgaac gcgcaactgg cggaaaaggc ggcaagatgt
    12421 gattttgtcg aacaggcaca cggcaaaacc gtgtcggaat tggcggtgtt ggacgggaaa
    12481 taccggcatt tgcaggacga aaattatgct ttgggcaacc gtttttccgc agccgaaaag
    12541 cagattgccc atttgcagga aaaagaggcg gagtcggcgc ggctgaagca gtcgtatatc
    12601 gagttgcagg aaaaggcaca gggtttggcg gttgaaaacg aacgtttggc aacgcagctc
    12661 ggacaggaac ggaaggcgtt tgccgaccaa tatgcgctgg aacgccaaat ccgccaaaga
    12721 gtcgaaaccg atttggaaga gagccgccaa actgtccgcg acgtgcaaaa cgacctttcc
    12781 gatgtgggca accgttttgc cgcagccgaa aaacagattg cccatttgca ggaaaaagag
    12841 gcagaagcgg agcggttgag gcagtcgcat atcgatttgc aggaaaaggc acagggtttg
    12901 gcggttgaaa acgaacgttt ggcaacgcaa atcgaacagg aacgccttgc ttctgaagag
    12961 aagctgtcct tgctgggcga ggcgcgcaaa agtttgagcg atcagtttca aaatcttgcc
    13021 aacacgattt tggaagaaaa aagccgccgt tttaccgagc agaaccgcga gcagctccat
    13081 caggttttga acccgctaaa cgaacgcatc cacggtttcg gcgagttggt caagcaaacc
    13141 tatgataaag aatcgcgcga gcggctgacg ttggaaaacg aattgaaacg gcttcaagga
    13201 ttgaatgcgc agctgcacag cgaggcaaag gccctgacca acgcgctgac tggtacgcag
    13261 aataaggttc agggtaattg gggcgagatg attctggaaa cggttttgga aaattccggc
    13321 cttcagaaag ggcgggaata tgtggttcag gcggcatccg tccgaaaaga ggaagacggc
    13381 ggcacgcgcc gcctccagcc cgacgttttg gtcaacctgc ccgacaacaa gcagattgtg
    13441 attgactcca aggtctcgct gacagcttat gtgcgctaca cgcaggcggc ggatgcggat
    13501 acggcggcac gcgaactggc ggcacacgtt gccagcatac gcgcgcatat gaaaggcttg
    13561 tcgctgaagg attacaccga tttggaaggt gtgaacacat tggatttcgt ctttatgttt
    13621 atccctgtcg aaccggccta cctgttggcg ttgcagaatg acgcgggctt gttccaagag
    13681 tgtttcgaca aacggattat gctggtcggc cccagtacgc tgctggcgac tttgcggacg
    13741 gtggcgaata tttggcgcaa cgagcagcaa aaccaaaacg cgctggcgat tgcggacgaa
    13801 ggcggcaagc tgtacgacaa atttgtcggc tttgtacaga cgctcgaaag cgtcggcaaa
    13861 ggcatcgatc aggcgcaaaa cagctttcag acggcattta agcaacttgc cgaggggcgc
    13921 gggaatctgg tcggccgcgc cgagaagctg cgtctgttgg gcgtgaaggc aaacaagcag
    13981 cttgcacgcg atttgaccga acgtgccaat gaaacaacgg cgttgtcgga atctttggaa
    14041 tatgtggcag aagatgaagc agtctgactt gtgcggaaaa gcttgtttca gcaggggcgg
    14101 gaatgccgaa agcgcggcgt aactgtaccg gttctgattt ggggttggtt tgaagtactt
    14161 accaaagcct tgtccggcga ggtacaccgg caaggcggcg gttgtctgag ccttttgcgt
    14221 ttcagacggc atcagtgcag atgatgccgt ctgaagaccg tagggaaggc ggttagaaaa
    14281 acggattgtg ccgcttttcg tgtccgatgg aagtcatacg cccgtgtccg gcgacaactt
    14341 gcacggtttc ggggagggcg aataatttgt tgcggatatt attgattaag tcggcgtggt
    14401 tgccgcgcgg aaaatcggtt ctgcctatgg tttcgtaaaa cagcacgtcg cccgcaatca
    14461 gcagctccgc ttcggcacaa tagaaaacca cgtgtcccgg cgtgtgcccc ggaatatgca
    14521 gcacttggaa ggcgtagcgt ccgactttga gcgtttcgcc ttcttcgagc caatggttcg
    14581 gcgcaaaggc gggcgagacg gggaatccgt attgcgcggt ggtttgcggc agcgattgga
    14641 gcaggaattc atcgtccgga tgaggcccga ggacgggaac tttacgcgtt ttcagcattt
    14701 cgaccacgcc gcccgcgtga tcgagatggc cgtgcgtcag ccagattgcc gtgagcgtga
    14761 gtttgcggtt tgccaacgct tgcagcagga acggcacgtc gccgccgaca tcggtcagga
    14821 cggcttcgcc gctttcgtcg tcccaaatca gggtgcagtt ttggcggaag ggggtaacgg
    14881 agaggatttc gtaacgtagg gtcatggcgt gttcctaaac ggtttttcag acggcatcgg
    14941 gtttgccgtt tgttttatgg cggtttgccg cctgtttgga tattggggga atcgggtgat
    15001 taagaagaca atcggcggca tcataccgat ttttatggcg gttttcatcc ctgcatcggc
    15061 aggcgcggcg gatttgatgt tggcgcagga atacaaagac caagagattg caggctgggc
    15121 aatgagcgag aaactcgacg gcgtgcgcgc ctattgggac ggaaagcacc tgataagccg
    15181 tcagggctat gcgtttacgc cccccaaagg ctttaccgcg cagtttccgc cttatccttt
    15241 ggacggcgaa ttgtatagcg gacgcggtca gttcgagcag atttccgcta ccgtgcgttc
    15301 tgtttcttca gactggcgcg gcatccgtct gcacgttttc gacgtaccca aggcgcaggg
    15361 caatctctac caacgtttgg cagtcgcaac gcagtggctg aaaacgcatc cgaacgcgcc
    15421 gattaccatc atcccgcaaa tcaaagtgcg cgaccggcag cacgcgatgg actttttaaa
    15481 acaaatcgaa gcgcagggcg gcgaaggcgt gatgctgcgc cagcccgaat cccgttatag
    15541 cggcggcagg agcagccaat tattgaagct gaaaagccaa tacgacgacg aatgcacggt
    15601 aacgcggcac tatgagggca aagggcgaaa cgccggacgg ctgggcgcgg tcggctgcaa
    15661 aaaccgacac ggcgaattcc gcatcggcag cggtttcaaa gacaaagacc gcgacaaccc
    15721 gcccaaaatc ggcacactga ttacctaccg ctaccgtggt tttacgcgga aaggcacgcc
    15781 gaaatttgcc acatttgtgc gcgtgcgtac cgaccgctga gcaggacagt tcagacggca
    15841 gccgatactt tggtttataa ttttcctttt accgaccgat tccgacatat gaccgattta
    15901 gaaaccaaac gccttgaaac acaggcgatg cttgaaaacg ccgatctttt gttcgaccaa
    15961 ggccaatgcc gtgccgcact gcaaaaagtg gcggacgaga ttacgcgcga tttgggcggc
    16021 aaatatccgc tgctgctgcc cgtgatgggc ggcgcggtgg tgtttacggg gcagttgctg
    16081 ccgctgttgc gttttccctt agattttgat tatgttcacg tttcccgtta cggcgacaag
    16141 ctggagggcg gcgcgttcaa ctggaagcgt atgcccgatg cggaacaaat ccggggcagg
    16201 cacgtcgtcg tgctggacga tattttggac gaagggcata cgatgtccgc cattcaagcc
    16261 aaacttttgg aaatgggtgc ggcaagctgc cgtgcggcgg tgttcgccaa caagctgatt
    16321 gacaaaccca agcctatccg agccgattat gtcggactgg atgtgccgaa ccgttatgtt
    16381 ttcggttacg gcatggatgc ggcgggctgc tggcgcaatc tgggcgagat ttacgcattg
    16441 gacggaaaat aaggacgcga tgccgtctga aggcctttca gacggcatcg cgcccatacg
    16501 ccggcaggat aatgaagaac aggacgcatc aatatgatag ggcttttaat catcacacac
    16561 gaaaccatag gcgaagccta ccgcaagctg gcacatcatt ttttcccggg cgggctgcct
    16621 gaaaacgtcc gcatactcgg cgtgcaaccg acggaagacc aagacgacat catcaacaac
    16681 gccattgccg cgcttcagga atttcccgac aacgacggcg tgctgattat gaccgatatt
    16741 ttcggcgcga ccccctgcaa tgcagcccgc cgcctcgtgc gcgaaaacaa atcggcgatt
    16801 ttgaccggac tgaacgcgcc gatgatggtt aaggccgtcc aatattcgcc ggcggcggaa
    16861 gaccttgccg cctttaccga atgtgtcaga gaggcggctg taaaaggcat tttcgccatc
    16921 acgtccgcgc ccgaagattt ggtgtgccgg cgcagcggcg atgccgtctg aagaagcggc
    16981 agggcaggaa aacattttaa acggcgtctg ctgccgatat acataacacg ggaaccgaaa
    17041 tgctcaaaca atccatcgaa atcatcaaca aactcggact ccacgcccgc gcgtccaaca
    17101 agttcaccca aaccgcgtcc caattcaaaa gcgaagtctg ggttacgaaa aacgacagcc
    17161 gcgtcaacgg caaaagcatt atggggctga tgatgctcgc cgccgccaag ggtacggtca
    17221 tcgaactgga gacggacggc gcggacgagg cggaagcgat gcgcgccctg accgacttaa
    17281 tcaacggcta cttcggcgag ggcgaataat gagtatcgtg ctgcacggtg tggcggcggg
    17341 caaaggcatt gccgtcggtt gcgcccacct gattgcgcgc ggtacggagg aagtgccgca
    17401 gtatgatgtt gcggaggcgg acaccgatgc cgaagccgaa cgtttcgatg ccgccgtcaa
    17461 agccacgcgc aaagagttgg aacagctccg cagcgcaatt cccgaaaacg ccccgaccga
    17521 gttgggcgcg ttcatctcgc tgcacctgat gctcttgacc gatgttacct tgtcgcgcga
    17581 acccgtcgat attttaaggg aacaaaaaat caacgccgag tgggcattga agcagcagag
    17641 cgacaaactc gccgcccaat tcgacaatat ggacgatgcc tatttgcgcg aacgcaagca
    17701 ggatatgctg caagtcgtcc gccgcatcca caacaacctg atcgggcagg gcaacgagtt
    17761 ggaagttgcc gacaacctgt ttgacgaaac cgttctgatt gcaaacgacc tttcgcccgc
    17821 cgacacggtt ttgtttaaag agcagcgcat tgccgccttc gttaccgatg ccggcggccc
    17881 caccgggcat acggcgattt tgggcaggag cttggacatc ccgtccgtcg tcgggctgca
    17941 caacgcgcgc aaactgatta ccgaaggcga aacggtcatt gtggacggta tcaacggcgt
    18001 gttgattatc gcgccggatg agtcggtgtt gaacgaatac cgccgccgtg cccgcgaata
    18061 ccgcagccac aaacgcgatt tgaacaagct caaaaaaacc gccgccgcca ccgccgacgg
    18121 ggtctgcatc gagcttgtgg gcaatataga atccgccgaa gacgtgaaac cgctgcacaa
    18181 cctcggcgca gacggcatcg ggctgttccg cagcgagttt ctttacctga accgcgatac
    18241 gatgccgtct gaagacgagc agtacgaagt gtacagcgcg attgtcaaaa aaatgaaagg
    18301 caaaagcgta acgatacgga cagtcgattt aggtgtggac aaaaacccgc gctggttcgg
    18361 gaaaaacagc acgcccaacg gcagcctcaa ccccgcgctg ggcatgaccg gcatccgcct
    18421 gtgccttgcc gaaccggtca tgttccgcac ccagatgcgc gccatcctcc gtgcggcggt
    18481 acacggcccc gtgcggatga tgtggccgat gattacctcc gtatccgaag tgcgccagtg
    18541 cctcatccac ctcgacaccg cgcaacgcca gcttgccgaa cgcggcgatg ccttcggtaa
    18601 agtcggcatc ggctgtatga ttgaaattcc gtctgccgcg ctgaccgtcg gcagtatttt
    18661 gaaactggtc gatttcatct ccgtcggtac caacgacctg attcaataca tcttgtccgt
    18721 cgatcgcggc gacgacagcg tcagccacct ctaccagccc ggccatcccg ccgtgctgaa
    18781 aatgctgcaa cacgtcatcc gtaccgccaa ccgcatggac aaagacgtat ccgtatgcgg
    18841 cgagatggcg ggcgataccg cgtttacccg cgttttattg ggtatggggc tgcgccgttt
    18901 ttccatgaac cccaacaaca tcctgcccgt caaaaacatc attctgcaca gcaatgtcgg
    18961 acagctcgaa agcgatattg cgaaagtcat ccgctgcgaa gacgaagaga agtcggaaaa
    19021 gctgatcaaa cagatcaaca gcgtgtctgt cgaggaagaa gccgacttca aggggcggaa
    19081 ataaatacgg caggtaaaaa atagaaatac ttaacaatgc ccgcaatctg aaattttgcc
    19141 attcttgcaa aatagaaaac cgaaacagaa acccaaaatc ggtcattccc tcaaaaacag
    19201 aaaaccaaaa tcagaaacct aaaatccgtc attcccgcgc aggcgggaat ctaggtttgt
    19261 cggcacagaa acttgtcggg aaaaacggtt tctttagatt tta
//
LOCUS       DAXIDM010000033        18998 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000033 DAXIDM010000000
VERSION     DAXIDM010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18998
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.033"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(1063..1731)
                     /locus_tag="ACFOAE_000940"
     CDS             complement(1063..1731)
                     /locus_tag="ACFOAE_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC6884449.1"
                     /translation="MKNLAIFDLDNTLINTDSDHAWPQYLIKKGLVDAAETEAQNEKF
                     YRDYQNGCLDIDAFLKFHLAPLARYSKEELAEFHREFMAEYIIPHISPMQRMLVQSHQ
                     MAGDETLVISSTNEFIITPVCRLFGITNIIGTQLESGSDGRYTGNYIGTPSLKEGKIT
                     RLNQWLAERGETLESYGKTYFYSDSKNDLPLLRLVDEPVAVNPDAELEKEAKEKGWPV
                     LNFK"
     gene            complement(1728..2396)
                     /gene="hda"
                     /locus_tag="ACFOAE_000941"
     CDS             complement(1728..2396)
                     /gene="hda"
                     /locus_tag="ACFOAE_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003693249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA regulatory inactivator Hda"
                     /protein_id="HFC6884450.1"
                     /translation="MNQLIFDFAAHDYPSFDKFLGTENAELVYVLRHKHGQFIYVWGE
                     EGAGKSHLLQAWVAQALEAGKNAAYIDAASMPLTDAAFEAEYLAVDQVEKLGNEEQAL
                     LFSIFNRFRNSGKGFLLLGSEYTPQQLVIREDLRTRMAYCLVYEVKPLTDQEKIDALA
                     SMAAARQVTVDSEIFEYLLKHWRRDMDSLMMMLDTLDNYAVTMGKRITLPLLRQLLKQ
                     QETQ"
     gene            complement(2428..4123)
                     /locus_tag="ACFOAE_000942"
                     /pseudo
     CDS             complement(2428..4123)
                     /locus_tag="ACFOAE_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707572.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(4412..5059)
                     /locus_tag="ACFOAE_000943"
     CDS             complement(4412..5059)
                     /locus_tag="ACFOAE_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF799 domain-containing protein"
                     /protein_id="HFC6884451.1"
                     /translation="MKPLILGLAAVLALSACQVQKAPDFDYTSFKESKPASILVVPPL
                     NESPDVNGTWGVLASTAAPLSEAGYYVFPAAVVEETFKQNGLTNAADIHAVRPEKLHQ
                     IFGNDAVLYITVTEYGTSYQILDSVTTVSAKARLVDSRNGKELWSGSASIREGSNNSN
                     SGLLGALVSAVVNQIANSLTDRGYQVSKTAAYNLLSPYSHNGILKGPRFVEEQPK"
     gene            complement(5056..5424)
                     /locus_tag="ACFOAE_000944"
     CDS             complement(5056..5424)
                     /locus_tag="ACFOAE_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4810 domain-containing protein"
                     /protein_id="HFC6884452.1"
                     /translation="MNPKTLSRLSLCAAVLALTACGGNGQKSLYYYGGYPDTVYEGLK
                     NDDTSLGKQTEKMEKYFVEAGNKKMNAAPGAHAHLGLLLSRSGDKEGAFRQFEEEKRL
                     FPESGVFMDFLMKTGKGGKR"
     gene            complement(5434..6105)
                     /locus_tag="ACFOAE_000945"
     CDS             complement(5434..6105)
                     /locus_tag="ACFOAE_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsgG/HfaB family protein"
                     /protein_id="HFC6884453.1"
                     /translation="MKTVSTAVVLAAAAVSLTGCATESSRSLEVAKVASYNTQYHGVR
                     TPISVGTFDNRSSFQKGIFSDGEDRLGSQAKTILVTHLQQTNRFNVLNRTNLNALKQE
                     SGISGKAHNLKGADYVVTGDVTEFGRRDVGDHQLFGIFGRGKSQIAYAKVALNIVNVN
                     TSEIVYSAQGAGEYALSNREIIGFGGTSGYDATLNGKVLDLAIREAVNSLVQAVDNGA
                     WQPNR"
     gene            complement(6270..6989)
                     /locus_tag="ACFOAE_000946"
     CDS             complement(6270..6989)
                     /locus_tag="ACFOAE_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC6884454.1"
                     /translation="MATLSNKTILVTGASQGLGEQVAKAYAAAGATVILVARHQKKLE
                     KVYDAIVEAGHPEPFAIRFDLMSAEEKEFNQFAATIAEATQGKLDGIVHCAGYFYALS
                     PLDFQTVAEWVNQYRINTVAPMGLTRALFPLLKQSPDASVIFVGESHGETPKAYWGGF
                     GASKAALNYLCKVAADEWERFGNLRANVLVPGPINSPQRIKSHPGEAKSERKSYGDVL
                     PAFVWWASAESKGRSGEIVYL"
     gene            complement(7073..8386)
                     /gene="hpnE"
                     /locus_tag="ACFOAE_000947"
     CDS             complement(7073..8386)
                     /gene="hpnE"
                     /locus_tag="ACFOAE_000947"
                     /EC_number="1.17.8.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="HFC6884455.1"
                     /translation="MMNTPHPRPKIAVIGAGWAGLSAAVTLARHADVTLFEAGRQAGG
                     RARTLAGNTDGFGFLDNGQHILLGAYRGVLRLMKTIGSDPRAAFLRVPLHWHMHGGLQ
                     FRALPLPAPLHILGGVLLARRAPTALKAKLLADMSDLQKSARLGQPDTTVAQWLKQRN
                     VPRAAVMQFWQPLVWGALNTPLETASLRVLCNVLSDGVLTKKSGSDYLLPKQDLGAIV
                     AEPALADLQRLGADIRLETRVCRLNTLPDGKVLVNGEAFDAAVPATAPYHAAALLPEG
                     TPEHVQTAYQNLRYHAITTVYLRYAEPVRLPAPLTGLADGTVQWLLCRGRLGLPENEV
                     SAVISVSDRVGAFTNRAWADKVHADLKRILPHLGEPEAVRVITEKRATTAADAPPPDL
                     SWLHRHRIFPAGDYLHPDYPATLEAAVQSGFAAAETCLQSLSDAV"
     gene            complement(8465..9337)
                     /gene="hpnD"
                     /locus_tag="ACFOAE_000948"
     CDS             complement(8465..9337)
                     /gene="hpnD"
                     /locus_tag="ACFOAE_000948"
                     /EC_number="2.5.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA];
                     GO_process: GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="HFC6884456.1"
                     /translation="MKGLDYCRQKAEESRSSFLSGFRFLTQEKRDAVTILYAFCRELD
                     DVVDECSNPDVAQATLNWWRGDLDKVFGGAMPEHPVNQALRQVKETFKLPKYELEALI
                     DGMQMDLVQARYGSFEELKLYCHRVAGVVGCLIARILGFSDNKTLEYADKMGLALQLT
                     NIIRDVGEDARNGRIYLPMEEMRRFDVPASVILQCRPTENFTELMAFQIKRARETYRE
                     AVSLLPDADKKAQKVGLVMAAVYYALLNEIDRDGAQNVLKYKIALPSPRKKRIALKTW
                     LFGFKPRPGTPERA"
     gene            9499..11361
                     /gene="hscA"
                     /locus_tag="ACFOAE_000949"
     CDS             9499..11361
                     /gene="hscA"
                     /locus_tag="ACFOAE_000949"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HFC6884457.1"
                     /translation="MALLQISEPGMSAAPHRHRLAAGIDLGTTNSLVATVRSGSAACL
                     PDAEGRVTLPSVVRYLENGGIEVGKTALSAQKTDPLNTVSSAKRLIGRTLADLHQNTH
                     YLPYRFGDNQRVIELHTRQGVKTPVEVSAEILKTLKSRAEETLGGDLVGVVITVPAYF
                     DDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNASEGTFVVYDLGGGTFDVSVL
                     QLTKGLFEVKATGGNSALGGDDFDHRLFCYLLEQNGLSQLNEQDSQLLLSLVRAAKEQ
                     LTTQTEARIQATLSDGMAIDTSISRAEFHNLTQHLVMKTLEPVKQALKDAGVGKNEVK
                     GVIMVGGSTRMLHVQQAVATFFGQTPLNNLNPDEVVALGAAIQANVLAGNKADGEWLL
                     LDVTPLSLGLETYGGLAEKIIPRNSTIPTARAQDFTTFKDGQTAMTIHVVQGERELVA
                     DCRSLAKFTLRGIPPMAAGAARIRVTFQIDADGLLSVSAQEQSTGVHAQIEVKPSYGL
                     DDGAITRMLKDSMDNAAEDMAARARAEAVVEAESLTDAVNAALELDSDLLDAEELQQI
                     RQGIADLQGRLKDGKAEDIRAAAAKLGSITDNFAAKRMNRNIQRALTGQSVDNI"
     gene            11438..12094
                     /locus_tag="ACFOAE_000950"
     CDS             11438..12094
                     /locus_tag="ACFOAE_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFC6884458.1"
                     /translation="MEKSGIVYLMKTVIKGVYKIGISEVSNFEGRMRHLENNGYANVA
                     GLERILAVKTDNYKEKENLLHEIFSKSRIGDTELFAVDENLVKRLFLSLRGEIVFPKN
                     ETAESEFEKSVHERRQEGNAGSGRKQLLDLVRRGHREYPYALPRLLAGAASYKPKKSK
                     IRLFKEAYFGKSGTRLTDEIADGIHIYTCFSRADLEKAYSEYLELFKSESDAEGRKPQ
                     "
     gene            12131..12892
                     /locus_tag="ACFOAE_000951"
     CDS             12131..12892
                     /locus_tag="ACFOAE_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2314 domain-containing protein"
                     /protein_id="HFC6884459.1"
                     /translation="MMGDSVIYYVEQADKPVNRAGERARKTFKYFWRELFWERRRIIP
                     ALDFAMVKAPFFQDGEDGEICEHMWIDDIYFDGLYIYGVLNNEPGELTNVEQGESVCV
                     PVDDISDWMFVCNGIPYGGFTIQAMRGQMTEEERTEHDAAWGIDFGDPGQVLLVYEEK
                     EHPENLEEHPMCRNCIDDFRQQLSQNPDFLHEQDEDGYTPLHHEAIAGNALMVQAMLE
                     YGANPASKTSEGYTALDFARLAGWQNVADLLEPRH"
     gene            12947..13288
                     /gene="fdx"
                     /locus_tag="ACFOAE_000952"
     CDS             12947..13288
                     /gene="fdx"
                     /locus_tag="ACFOAE_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009425374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HFC6884460.1"
                     /translation="MPKITVLPHTTLCPEGAVIEDAPEGKTVLDVLLDHDIEVDHACE
                     KSCACTTCHVIIRKGFDSLEEPTELEEDLLDQAWGLEADSRLSCQAVVAGEDLIVEIP
                     KYTINHAREEH"
     gene            complement(13608..14162)
                     /locus_tag="ACFOAE_000953"
     CDS             complement(13608..14162)
                     /locus_tag="ACFOAE_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFC6884461.1"
                     /translation="MNNMFAAKLSKLVYTASDHPDPLSEMGEFDRLILLIRKLYQILD
                     GQHTLSRVTVCLHYRSRRGLIALDKAAAGCDAAMLRAQRWRIYTQIAERLAGSDGGFT
                     VTAESVSAACPELEGRYLELVRRAAVSFGFTQGWENPAGGQEKTQAVPDAASGHSVRK
                     PIKINIEAKVECYPAYRPTVALKV"
     gene            14375..14572
                     /gene="iscX"
                     /locus_tag="ACFOAE_000954"
     CDS             14375..14572
                     /gene="iscX"
                     /locus_tag="ACFOAE_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HFC6884462.1"
                     /translation="MKWTDTQRIAEDLYDLHGEDIDPKSLRFTQLRDLIMALPEFDDD
                     PARCGERILEAVQQAWIDEAE"
     gene            complement(14640..15041)
                     /locus_tag="ACFOAE_000955"
     CDS             complement(14640..15041)
                     /locus_tag="ACFOAE_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFC6884463.1"
                     /translation="MKDKHHSSAMRLDKWLWAARFFKTRSLAQKHIELGRVQVNGSKV
                     KNSKTIDIGDIIDLTLNSLPYKIKVKGLNHQRRPASEARLLYEEDTKTATLREERKQL
                     DQFSRITSAYPDGRPTKRDRRQLDRLKKGDW"
     gene            15252..16211
                     /locus_tag="ACFOAE_000956"
     CDS             15252..16211
                     /locus_tag="ACFOAE_000956"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HFC6884464.1"
                     /translation="MKPVFLDFEQPIAELTNKIDELRFVQDESAVDISDEIHRLQKKS
                     NDLTKSIFSKLTPAQVSQVSRHPQRPYTLDYIEALFTDFEELHGDRHFADDHAIVGGL
                     ARFNGQSVMVVGHQKGRDTKEKIRRNFGMPRPEGYRKALRLMKTAEKFGLPVMTFIDT
                     PGAYPGIGAEERGQSEAIGKNLYELTRLRVPVLCTVIGEGGSGGALAVAVGDYVNMLQ
                     YSTYSVISPEGCASILWKTAEKAADAAQALGITADRLQKLDLVDTVIKEPLGGAHRDF
                     GQTMKNVKAVLEKQLHEAQSIPLADLLSRRFDRIMAYGKFSEQ"
     gene            16279..17589
                     /gene="tilS"
                     /locus_tag="ACFOAE_000957"
     CDS             16279..17589
                     /gene="tilS"
                     /locus_tag="ACFOAE_000957"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFC6884465.1"
                     /translation="MLTLDAFEQCLKDCFPQGLNGKKTAVALSGGLDSVVLLHLLVRA
                     GKKGGFIPNALHIHHGLSPRADDWADFCQNYCDMLGVGLETVKVCVEKNGLGIEAAAR
                     QKRYAAFAEKGFDVLALAHHRDDQIETFMLAVARGGGLRALAAMPAVRPFGEKGIIWR
                     PLLPFSRQDIWDYAQKHGLLNIEDESNTDTAYLRNRFRHRILPELSAQIPHFGRHVLN
                     NVRALQEDLALLDEVVVQDCRWVCGAGYFDTARWLTFSPRRKTHILRHFLKENGIPVP
                     NQNALADIARVLTEAKTGRWNVQGFELHHYAGRLFVFRLEKTDKLRFLKDRQISGNLR
                     EILTRQGFVLKRHPFGLPGHLLEQDGILRAVAASDTLAVGGIHKDVKKILQEKRVLPV
                     LRPFWPVVADKDNRPLVLANYGTDFQISVSDGILPVHPDFPILF"
     gene            17663..18448
                     /locus_tag="ACFOAE_000958"
     CDS             17663..18448
                     /locus_tag="ACFOAE_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFC6884466.1"
                     /translation="MKHISSTNNEHIRHLHHLLSQGKFRRQYAQSVLEGVHLLQVFLQ
                     SGRKPVGVYIPEAKMPSEEARKLTAVLPEDRIFSVSDGILKKISSLSCADDILALIDI
                     PLGGTLPDKGDCVVLDGVQDPGNVGTVLRSAAAAGIGVVVLGKGCADAWSPKVLRAGM
                     GAHFLLDIYSQADLEIWLASYKGRVFATALREEKQAVLYGEDLCEPTAWVFGNEGAGV
                     GKAVLDRADKCVRIPMHDATESLNVAMAATICLFEQMRQRSAY"
     gene            18458..18655
                     /locus_tag="ACFOAE_000959"
     CDS             18458..18655
                     /locus_tag="ACFOAE_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884467.1"
                     /translation="MPSEKIYYGVLIFLCIASMLLSPFFYAGALKPKKAALRKDGQWK
                     LILLSNTVAAAVLFWMWWKWF"
BASE COUNT         4382 a         4668 c         5347 g         4601 t
ORIGIN      
        1 tcgccttgtc ctgatttttg ttaatccact atacgtccta gattcccact ttcgtgggaa
       61 tgacgggatg tgggtttttg tgcggatttg aaccggtaag ggtggtgtgg gattggtggt
      121 ttgcttagga tcttttggat tgtattttgt atatacattt acttgttgat aaaagataaa
      181 ataaaattag aaactaaaag tgagaaaaaa ttaataataa tagggatgta taaatgtaaa
      241 ggctccgttt catagctaag gttatctgaa tatatggaaa aaaagtaaaa gtcaaaacta
      301 aaatatatag ataatgctaa tgataataga attatcactt tcctagagta aggataatat
      361 ttttttatcg taaaaaaata taaaatagga taaataattg ccatatagat agattttgta
      421 acaaaattaa aaataaataa taaaaataat gtaataaagt atattttttg gctatgaaat
      481 aaaattgtac ataattgaac gagcagatca aaaaatgaac tacatataac aataaataat
      541 aacgtattta ccatactaaa tttaataggt ctcattatca tatttaataa ccacttcata
      601 gtatagtgga ttaaatttaa accagtacag cgttgcctcg ccttgccgta ctatctgtac
      661 tgtctgcggc tttgtcgcct tgtcctgatt tttgttaatc cactataaat gcagagtggg
      721 tggaaacact cactttatgg tttgctacgc tctgctcaat tagcaacccg ataacccaat
      781 atggataata gggtaattaa tccaatctaa tttgtcagta tccgttaatt tattgcaaaa
      841 taaagtattg aattatgtcg ggtgcaaatg acgaaatata agtttccgtg cggacggatc
      901 aagattccca ctttcgtggg aatgacggtg gaaagattgt tgtttttccc gatgaattcc
      961 tgtgtttttt gtttttccgg ataaattcct gtggctttga gttttttgga tttcagcctc
     1021 aatgccgtct gaacgccgaa tcgggcttca gacggcattg cgtcatttga aattcaaaac
     1081 cggccagcct ttttctttgg cttctttttc cagctcggca tcggggttga cggcgacggg
     1141 ttcgtcgacg aggcgcagca gcggcaggtc gtttttggag tcgctgtaaa aataggtttt
     1201 gccgtagctt tcgagcgttt cgccgcgttc ggcgagccat tggttcaggc gggtgatttt
     1261 accttctttg aggctgggcg tgccgatgta attgccggtg tagcggccgt cggaaccgga
     1321 ttcgagttgt gtgccgatga tgttggtaat gccgaaaagg cggcagacgg gggtgatgat
     1381 gaactcgttg gttgaggaaa tcacaagggt ttcgtcgcct gccatttggt ggctctgcac
     1441 cagcatacgc tgcataggcg agatgtgggg gatgatgtat tccgccataa attcgcggtg
     1501 aaactctgcc agctcttctt tgctgtagcg ggcgagcggg gcgaggtgga atttgaggaa
     1561 tgcgtcgatg tcgaggcagc cgttttggta gtcgcggtag aatttttcgt tttgcgcttc
     1621 ggtttcggca gcgtcaacca agcctttttt gatgaggtat tgcggccagg cgtggtcgga
     1681 atcggtgttg atgagggtgt tgtcgaggtc gaagatggcg aggtttttca ttgggtttcc
     1741 tgttgtttca aaagctggcg caaaagcggc agggtgatgc gtttgcccat tgtgacggcg
     1801 tagttgtcca gcgtgtcgag catcatcatc aggctgtcca tatcgcgccg ccagtgtttg
     1861 agcaggtatt cgaaaatttc ggaatcgacg gttacttggc gtgccgccgc catactggcg
     1921 agcgcgtcga ttttttcttg gtcggttaag ggcttgactt cgtaaacgag gcagtacgcc
     1981 atacgcgtcc gcaaatcttc gcggatgacg agctgctggg gcgtgtattc cgaaccgagc
     2041 agcaaaaagc ctttgccgct gttgcggaag cggttgaaga tggaaaaaag cagggcttgt
     2101 tcttcgttgc ccagcttttc gacttgatcg acggcgaggt attccgcctc gaacgcggca
     2161 tcggtcagcg gcatggaggc ggcatcgata taggcggcgt ttttgccggc ttcgagcgcc
     2221 tgtgcgaccc acgcctgcaa aagatggctt ttgcccgcac cttcttcacc ccagacatag
     2281 ataaactgtc cgtgtttgtg tcggaggaca tagaccagtt ccgcgttttc cgtgccgagg
     2341 aatttgtcga aactcggata gtcgtgtgcg gcaaagtcga aaataagctg gttcacggtt
     2401 cggcattccg aggggtggta aacgggttta ttgtacgttg ttttcgcgcg cctttccaat
     2461 ttgaacgatg ccgacatcga ggcgcatatt gtggaacgcg ttgagcgtgc ttcggtgtcc
     2521 gatgctgatg atgatgctgt cgggcagttt ttgctttaag gcgcggtaga gcgcggcttc
     2581 ggccggttcg tccaaggcgg cggtggcttc gtcgagcagg acgattttgg gcttggaaag
     2641 cagggcgcgg acgaaggcga cgcgttgcag ttcgcccggg gagagtttgt gctgccagtc
     2701 gtctgttttg tccaatttgt caatcagata acccaagcgg caggtgttca tggcttcggc
     2761 taactcggga tgctgtttgt cgatgtccgg ataacaaacc gcgtcgcgca ggctgccctg
     2821 tgccgtgtac gggcgttgcg gcaggaagag gatgtcttga tgcggcggac ggctgacttt
     2881 gccgctgctg ccgaacggcc aaagcccagc cagcgcgcgc agcagcgagg ttttgccgca
     2941 accgctcggg ccgcgtatca gcagcgaatc gccgcttttg agtttgatgt tgatgccgtc
     3001 caataaaact tcgccgttgt ggcggaacag ggcgacgttt tcctgtgcaa tgccgtctga
     3061 aacttcgcta atctcgggtt gccgcgcgct gtgttgttct tcggtactca gcaaaaagcc
     3121 gtacagacgc tccaatcggg cgcggtaggc ggtgaatttg ttgtagaaca ttcgaaagaa
     3181 agaaagcgcg ttttgcagtc gcgcgaaggc ttggacggtt tgctggatgt cgccgatttt
     3241 gatttgtccg gcaaacaggc gcggagcttg caaaataatc gggaagagtt tgatgccgtt
     3301 ggtgaacata tcgttaaagc cgcttaagca gacgctttgc cgcgcaatgc gccaacggtt
     3361 gcggataatg gctttaaagc ggtcggaaag ctggtcgtat tcatgttttt cgccgttgta
     3421 aaacgccacg ctttcggcgt ggtcgcgcac gcggatgagg gaataacggt agtcgccgtt
     3481 gagtttttcg ttttcataat tgtaacgaat caaagggttg cctatccaca tggcgataaa
     3541 ggtcgccaaa atcacaaata tatagacaaa ccaaacgatg ccgtgcggaa tgtcgaagcc
     3601 gaacacggtc aggatgccag ccaagccccg caaaacaacg gcaaattcca gagaagtaac
     3661 gaccgaattg accatgccgc gcacaaattc gatggtcgaa gcgataaatt cctgcgcgtc
     3721 ctgttggata cgctggtcga tgttgtctgg cgcgtggcgg cgcatttgca ggcggtagta
     3781 gtttttgtcg gcaagccagc gtgctgtcag cacttcgttg agccgctccg accatttaat
     3841 cgccaagcct tgatcgagga agtcgttgac gacgttgtta aacgcccgta tcagcaccac
     3901 gcccgcgttc attgcagcaa acatccaaaa tgccgaagca tttcaaatcc tgcatcgagt
     3961 cgtaaagccc tttggacata aaggtactca acacattcag ccgcatttcg gttaacacca
     4021 gcgtaatcat cgccgtaatc agcagcaaga ctttgaccgc gcttttcagt gtcagacaaa
     4081 gccaaagcgg tgtggaataa agctcggttt gccatttctg catgggaaat ttcttacggt
     4141 atcaatgccg tctgaaaaag acgggtacag ttgatttttt gatgaagttt ggggaagttt
     4201 tgcaggtcag ggcatattgc gtgttaattt accatacaac cacgccggaa ttaagtttaa
     4261 atttgaataa aaggttcggg ttctgcaaaa tacagaaccc gaaccttgtt cggatattga
     4321 aaccggccgc ccgattttgg gcggtgcggc ttgcaagtat caagattcgc atatgccgtc
     4381 tgaagctcgg agaggttcag acggcatatg cttatttggg ctgctcttcg acgaatctcg
     4441 gacctttcaa gatgccgttg tgagaatagg gcgacagcag gttgtatgcg gcggttttgg
     4501 aaacctgata accgcggtcg gtcaggctgt tggcaatctg attgaccact gcgctgacca
     4561 aagcccccaa caggccgctg ttgctgttgt tgctgccttc gcggatgctg gccgaacccg
     4621 accacaactc ttttccgttg cgggaatcga ccagccgtgc tttggcggat acggtcgtca
     4681 cgctgtctaa aatttgatat gaagtgccgt attcggtaac cgtaatgtac aaaaccgcat
     4741 cattgccgaa aatctgatgc agtttttccg gccggacggc gtgaatatcg gcggcattgg
     4801 tcaagccgtt ttgtttgaag gtttcctcca cgactgcggc ggggaagacg taatagccgg
     4861 cttcggaaag cggcgcggcg gtcgaagcca gtacacccca tgttccgttg acatcgggcg
     4921 attcgttcag cggcggaacc accaaaattg aagccggttt gctttccttg aatgacgtgt
     4981 agtcgaaatc gggcgctttt tgaacttggc aggcagacag cgccaacacg gcggcaagcc
     5041 ctaaaatcaa aggtttcatc gcttgcctcc tttaccggtt ttcatcagga agtccataaa
     5101 tacgcccgat tcgggaaaca gccttttctc ttcttcaaac tggcggaacg cgccctcttt
     5161 gtctcccgaa cgggaaagca gcagtcccag atgggcgtgc gcacccgggg cggcattcat
     5221 ttttttgttg ccggcttcca caaagtattt ttccatcttt tcggtctgct tgcccaacga
     5281 agtgtcgtcg tttttcaaac cttcatagac ggtatcggga tagccgccgt aataatacag
     5341 ggatttttgc ccgttgccgc cgcaggcggt cagagccaag accgccgcac acagcgacaa
     5401 acggctcaag gttttcggat tcatcatttc tccttaacgg ttgggttgcc atgcgccgtt
     5461 gtcaacagcc tgaaccaggc tgttgacggc ttcgcggatt gccaagtcta aaactttgcc
     5521 gttcaaagtc gcatcgtagc cggaagtgcc gccgaaaccg atgatttcac ggttggaaag
     5581 tgcgtattcg cccgcgccct gtgcggaata gacgatttcg gaagtattga cgttgacgat
     5641 attcagagcc acttttgcat aggcgatttg cgatttgccg cgaccaaaaa tgccgaagag
     5701 ctgatgatcg ccgacatctc tgcgtccgaa ttcggttaca tcgccggtaa cgacataatc
     5761 tgcgcctttc aggttatgcg ctttgccgga aatgccggat tcctgtttta atgcgttcaa
     5821 attggtgcgg ttcagtacgt tgaagcggtt ggtctgttgc aggtgcgtta ccagaatggt
     5881 ttttgcctgg ctgcccaaac ggtcttcccc gtcggagaaa atgccttttt ggaagctgga
     5941 gcggttgtcg aatgttccga cggaaatcgg ggtacgaaca ccgtgatatt gcgtattgta
     6001 ggaggcgact tttgctacct cgagactgcg tgaggattcg gtcgcacagc cggtcagtga
     6061 aacggcagcg gcggcaagga caacggcggt ggaaacggtt ttcataaaat ttaccctaag
     6121 gtcaagttaa ggaaataacg ggttgtcatt attgtcctta tgtaaattta agtcaaggtg
     6181 tttgtctgtg cgggacggat gcgcgcggaa ggtacggata tttttcaaac ggaatcgcgg
     6241 cgcgggcggg atgcctgcct tttccggatt tagaggtaaa cgatttcgcc actccgccct
     6301 ttgctttcgg cacttgccca ccagacaaat gcgggcagca cgtccccgta gcttttgcgt
     6361 tcgcttttgg cttcgcccgg atgggatttg atgcgttgcg gggaattgat gggtccgggg
     6421 acgaggacgt tggcgcgcag gttgccgaag cgttcccatt cgtcggcggc gactttgcac
     6481 aggtagttca acgcggcttt ggacgcgccg aagccgcccc agtaggcttt gggtgtttcg
     6541 ccgtggcttt cgccgacgaa gatgacggac gcgtcgggcg actgcttcag cagcgggaac
     6601 agggcgcggg tcagccccat aggtgcgacg gtgttgatgc ggtattggtt gacccattcg
     6661 gcgacggttt ggaaatccag cggcgagagg gcgtaaaaat agccggcgca gtggacgatg
     6721 ccgtccagtt tgccttgcgt ggcttcggca atggtggcgg cgaactgatt gaattctttt
     6781 tcttccgcac tcatcaggtc gaaacggatg gcgaagggtt cggggtgtcc ggcttcgaca
     6841 atcgcgtcat agactttttc cagttttttc tgatggcgtg ccaccagaat cacggttgcg
     6901 cctgccgccg cataggcttt ggcgacctgt tcgcccagac cttgcgatgc gccggtaact
     6961 aagatggttt tgttggacag tgtcgccata ctttttcctt tttggtggtc ggtcgggggt
     7021 attttagcgt tttgccgcac cttgtaaagc gtcccgatac cagccggcgt tttcagacgg
     7081 catcgctcag gctttgcagg caggtttccg ccgccgcgaa acctgattgt acggcggctt
     7141 cgagcgtggc ggggtagtct gggtggaggt agtcgccggc ggggaagatg cggtgccggt
     7201 gcagccacga caaatccggc ggcggggcat cggctgcggt tgtggcgcgt ttttcggtga
     7261 tgacgcgcac ggcttcgggt tcgcccaaat gcggaaggat gcgtttgagg tcggcgtgaa
     7321 ctttgtccgc ccacgctcgg tttgtaaacg cgccgacgcg gtcggaaacg ctgatgacgg
     7381 cggacacttc gttttcaggc agtccgagcc tgccccggca aagcagccat tgcaccgtgc
     7441 cgtcggcaag gccggtcagc ggggcgggca ggcggacggg ttcggcgtag cgcagataga
     7501 cggtggtgat ggcgtggtag cgaaggtttt gatatgccgt ctgaacgtgt tcgggcgtgc
     7561 cttcgggcag gagcgcggcg gcgtggtagg gcgcggtggc ggggacggcg gcatcgaaag
     7621 cttcgccgtt gacgagcact ttcccgtccg ggagggtgtt cagacggcat acgcgcgttt
     7681 cgaggcggat gtccgcgccg agccgttgaa gatccgccaa ggcgggttcg gcgacgattg
     7741 cgcccaaatc ctgcttgggt aggagatagt cgctgccgga ttttttcgtc agcacgccgt
     7801 cggacaaaac gttgcacaac acgcgcaggc ttgcggtttc caaaggcgtg ttgagcgcgc
     7861 cccaaaccaa gggctgccaa aactgcatca cggcggcacg cggcacgttc cgctgtttca
     7921 gccattgcgc cactgtcgtg tcgggctgtc cgaggcgtgc ggacttctgc aaatcggaca
     7981 tatcggcaag cagtttggct tttaatgcag tcggtgcacg ccgggcaagc agcacgccgc
     8041 ccaaaatatg cagcggcgcg ggcaggggga gggcgcggaa ctgcaaaccg ccgtgcatat
     8101 gccagtgcag cggtacgcgc aaaaaggcgg cacggggatc cgaaccgatg gttttcatca
     8161 ggcgcaacac gccccggtat gcgccgagca aaatgtgctg cccgttgtcc aaaaaaccga
     8221 aaccgtcggt atttccggcc agtgtgcgcg ccctgccgcc cgcctgccgg ccggcttcaa
     8281 acagggtaac gtcggcgtgc cgcgccaagg tgacggcggc ggacagtcct gcccagcctg
     8341 cgccgatgac ggcgattttc gggcgcggat gcggcgtgtt catcatttat tcctccaatg
     8401 gttgaaaccc cgtttttcgg ggcggcgggg gttgggtttt cctgaagggc gggcggtatg
     8461 cgccttatgc ccgttccggc gtgccggggc gcggtttgaa tccgaataac caggttttca
     8521 gggcaatgcg ttttttgcgc ggcgaaggga gggcgatttt gtatttgagg acgttttgcg
     8581 cgccgtctcg gtcgatttcg tttaaaagcg cgtaataaac cgccgccata accagtccga
     8641 ctttttgggc ttttttgtcg gcatcaggca gcagcgatac ggcttcacgg taggtttcac
     8701 gcgcacgctt tatttggaat gccatcaatt cggtgaaatt ttctgtcggc cggcactgca
     8761 aaatcacact tgcggggaca tcaaaccgcc gcatttcctc catcggcagg taaatccgcc
     8821 cattacgggc gtcttcgccg acatcgcgga tgatgttggt cagttgcagc gcaagtccca
     8881 ttttgtcggc gtattccagt gttttgttgt ctgaaaaccc caaaatccgc gcaatcaggc
     8941 agccgactac gcctgcgacg cggtggcaat acagtttcaa ttcctcaaaa ctgccgtaac
     9001 gcgcctgaac caaatccatc tgcatcccgt cgattaaggc ttccagttca tatttcggca
     9061 gcttgaaggt ttccttaact tgccgcaagg cctgattgac ggggtgttcc ggcatcgcgc
     9121 cgccgaatac cttgtccaaa tcgccgcgcc accagttcaa tgttgcctgt gcaacatcgg
     9181 ggttggaaca ttcgtcaacc acatcgtcca attcgcggca aaaggcatat aaaatcgtta
     9241 ccgcatcccg tttttcctga gtcaggaaac ggaagcccga taaaaaactg gagcggcttt
     9301 cttctgcttt ttgacggcaa tagtcgagtc ctttcacgat ttatattcct aatgatgggc
     9361 gggaaaggcg gattttatcg gcatttggcg gtagagggca atttcggcgg cacgacccaa
     9421 tccttagcgg tttgctcaac tatcggcgcg aattctgtta aaatgccgct ttacacaccg
     9481 caccgacagg cagaatttat ggctcttttg cagatttcag aaccgggtat gtccgccgcc
     9541 ccgcaccggc accgtttggc agcaggcatc gatttgggta cgaccaacag cttggttgcc
     9601 accgtccgca gcggcagtgc cgcctgcctg cccgatgccg aagggcgcgt taccctgcct
     9661 tccgtcgtcc gctatctgga aaacggcggc attgaagtcg gcaaaaccgc cctgtccgcc
     9721 caaaaaaccg acccgctgaa caccgtcagc tccgccaaac gccttatcgg gcggacgctt
     9781 gccgatctgc atcaaaatac gcactacctg ccttaccgtt tcggcgacaa tcaacgcgtt
     9841 atcgaattgc atacgcggca gggggtgaaa acgcctgtcg aagtgtcggc ggaaatcctc
     9901 aaaaccctta aatcgcgcgc cgaagaaacc ttgggcggcg atttggtcgg cgtggtgatt
     9961 accgtccccg cctatttcga cgatgcccaa cgccaggcca ccaaagatgc cgcgcggctg
    10021 gcgggtttga acgtattgcg cctgctcaac gaacccaccg ccgccgcaat cgcctacggg
    10081 ctggacaacg cctcggaagg cacgtttgtc gtgtacgact tagggggcgg cacattcgac
    10141 gtatccgtat tgcaactgac caaaggactg tttgaagtca aagccaccgg cggcaacagc
    10201 gcgttgggcg gcgatgactt cgaccatcgt ttgttctgct acctgctcga acaaaacgga
    10261 ctctcccaac tcaacgaaca agacagccaa ctcctgcttt cgctcgtccg cgccgccaaa
    10321 gaacaattaa ccacgcaaac cgaagcgcgc attcaggcga cgctttcaga cggcatggca
    10381 atcgacacaa gcatcagtcg cgccgagttc cacaacctga cgcagcattt ggtgatgaaa
    10441 acgctcgaac cggtcaaaca ggcgttgaaa gatgccggtg tcggtaaaaa cgaagtcaaa
    10501 ggcgtaatta tggtcggcgg ttcgacccgt atgctgcacg tccagcaggc agtcgccacc
    10561 tttttcgggc aaaccccgct gaacaacctc aaccccgacg aagtcgtcgc gctcggcgca
    10621 gccatacagg cgaacgtcct cgcaggcaac aaagccgacg gcgaatggct gctgctggac
    10681 gttacgccct tgtcgctcgg tttggaaacc tatggcggct tggcggaaaa aatcatcccg
    10741 cgcaattcca ccatccccac cgcgcgcgcg caggacttta ccaccttcaa agacggtcag
    10801 accgcgatga cgatacacgt cgtacaaggc gaacgcgaac tggttgccga ctgccgcagc
    10861 cttgccaaat tcaccctgcg cggcattccg ccgatggcgg cgggtgcggc gcgtatccgc
    10921 gtaaccttcc aaatcgatgc ggacgggctg ctgtccgttt ccgcccaaga acaaagtacc
    10981 ggcgtacacg cgcaaatcga agtcaaacct tcctacggtt tggacgacgg cgcgattacc
    11041 cgaatgctta aagacagtat ggacaacgcc gccgaagata tggcggcacg cgcccgcgcc
    11101 gaagccgtgg tcgaagccga aagcctgacc gatgccgtca acgccgccct cgagttggac
    11161 agcgatttgc tggatgccga agaattgcaa cagattcggc aaggtatcgc cgatttgcaa
    11221 ggccgtctga aagacggaaa agccgaagac atccgcgccg ccgccgccaa actcggcagc
    11281 atcaccgaca atttcgccgc caaacgcatg aaccgcaaca tccaacgtgc gctgacaggc
    11341 cagagtgtcg ataatatttg atacttaaac ggtttcagac ggcatagaga taacctgatg
    11401 ccgtctgaag gctcgaaaac acttgaaaaa catcgatatg gaaaagtcag gcattgtcta
    11461 tctgatgaaa accgtcatca agggcgtata taaaatcggc atttcggagg taagcaattt
    11521 tgaaggcaga atgcgccatt tggaaaacaa cggctatgcg aacgttgccg gattggagcg
    11581 catcctcgcc gtcaaaaccg acaattacaa agaaaaagaa aacctgctcc atgaaatttt
    11641 cagcaaaagc aggataggcg ataccgaatt gttcgccgtg gacgaaaacc ttgtaaaacg
    11701 tttgttttta tcgcttcgcg gcgaaatcgt gtttccgaaa aacgaaacgg cggaatcgga
    11761 atttgaaaaa agcgtccacg aacgcaggca ggaagggaat gccgggtccg gccgcaaaca
    11821 actgcttgat ttggtacggc gcggacaccg ggaataccct tacgcgctgc cccggctttt
    11881 ggcgggcgcg gcatcctaca agccgaaaaa atcgaaaatc cgccttttta aagaagcata
    11941 tttcggcaaa agcggcacga ggctgaccga cgaaattgca gacggcatcc atatttacac
    12001 ctgtttttcg cgggcggatt tggaaaaagc ctattccgaa tatttggaac ttttcaaatc
    12061 cgaatcggat gccgaaggca gaaagccgca gtaaggtgca aacagatacc gtacacgttg
    12121 aggagcagat atgatgggcg attccgtcat ttattatgta gaacaggcag acaaaccggt
    12181 aaaccgtgcc ggcgaacgcg cccgcaaaac attcaaatat ttttggcgcg agcttttttg
    12241 ggaacgccgc cgcatcattc ccgccttaga ttttgccatg gtcaaagccc cttttttcca
    12301 agacggcgaa gacggcgaaa tttgcgaaca tatgtggatc gacgatattt attttgacgg
    12361 tctttacatt tatggcgtgc tgaacaatga acccggcgaa ctgaccaatg tcgaacaagg
    12421 cgaaagcgtt tgcgttccgg ttgacgacat cagcgactgg atgttcgtgt gcaacggcat
    12481 tccctacggc ggctttacca tacaggcaat gcgtggacag atgacggaag aggagcgtac
    12541 cgaacacgat gccgcatggg gaatcgattt cggcgatccc gggcaggtat tgctggtgta
    12601 tgaagaaaaa gaacatcccg aaaatctgga agagcatccg atgtgccgga actgtattga
    12661 cgattttcgg caacagttgt cccaaaatcc ggattttctg catgagcagg acgaagacgg
    12721 ctatacgccg cttcatcatg aagccatcgc aggaaatgca cttatggttc aagccatgct
    12781 tgaatacggc gcaaatcctg cctcaaagac atcggaaggc tataccgccc tcgattttgc
    12841 ccgcctggcg ggctggcaaa atgttgccga cctgctcgaa ccgcgacatt aggcggacag
    12901 ttttccgaaa acgaacacaa acacttttta cagaaagaca ataaaaatgc ccaaaatcac
    12961 cgtacttcca cacacgacat tatgccccga aggcgcggtt atcgaagacg cgcccgaagg
    13021 caaaaccgtc cttgacgtgc tgctcgacca tgatatcgaa gtcgatcacg cctgcgaaaa
    13081 atcctgcgcc tgcaccacct gccacgtcat catccgcaaa ggtttcgaca gtttggaaga
    13141 accgaccgaa ttggaagaag acctgctcga ccaggcttgg ggtttggaag ccgattcacg
    13201 cctgagttgt caggcggttg tcgccggcga ggatttgatt gtggaaatcc ccaaatacac
    13261 catcaaccac gcgcgagaag aacactgaaa acaggccgtc tgaagccggc gcgcttcaga
    13321 cggcattgtt gcgcggataa ggcgcaatta ccggaaacag gcgttcgtac aggcggaaat
    13381 ttcgattcta tattgatttt tatcggtttt ctgacggaat gatccagtgc ggcatccgag
    13441 acggattgct cggacgcgat gcacgggtat ttatcggttt tgcagccgga aaaaccgccg
    13501 gcgggttata gtggattaaa tttaaaccag tacagcgttg cctcgccttg ccgtactatt
    13561 tgtactgtct gcggcttcgt cgccttgtcc tgatttttgt taatccacta tacttttagg
    13621 gcgacggtcg ggcggtatgc cggatagcat tccactttcg cttctatatt gattttgatt
    13681 ggttttctga cggaatgacc cgatgcggca tccgggacgg cttgtgtttt ttcctgcccg
    13741 cctgccggat tttcccatcc ttgcgtgaaa ccgaaagaga cggcggcgcg gcggacaagc
    13801 tcgagatagc gtccttcaag ctccgggcag gcggcggaca cgctttctgc cgtaaccgtg
    13861 aagccgccgt ccgacccggc aaggcgttcc gcaatctgcg tgtagatgcg ccaacgttgg
    13921 gcgcgcaaca ttgccgcatc gcaaccggca gccgctttat ccaaggcaat caggccgcgc
    13981 ctgctccggt agtgaaggca aaccgttact ctggagaggg tatgttgccc gtccaatatt
    14041 tgatacagct tgcgtatcag caaaatcagg cggtcaaact cccccatctc cgacaggggg
    14101 tcgggatggt cggaagcggt ataaaccagt ttggacaatt ttgcggcaaa catattgttc
    14161 atcaatcttc cttgtcggtt gaaaccccgc tcttcagggc ggtagaatca gatttgtttg
    14221 ggagaggcag ctcctcccga atcaggacga cacataaggt ggtgcttgat gtgttgtccg
    14281 gcgagttgaa acattcagcc atcctcaaag ggcggcagtt ttgccgaaac atattctaca
    14341 cggcttcaat gccggacgat aaaaggaaat tcatatgaaa tggacagaca cacaacgtat
    14401 cgctgaagac ctttacgacc ttcacggcga agatatcgac cccaaaagcc tgcgctttac
    14461 ccaattgcgg gatttgatta tggcgcttcc cgaattcgac gacgaccccg cccgttgcgg
    14521 cgaacgcatc ctcgaagccg tgcagcaggc atggatagac gaggcggaat aagtttcggg
    14581 aatgccgtct gaaatgcggc ggtacgcggt tcgtgcttct gtttgcagcg ggaacggttt
    14641 taccagtctc cttttttcag cctgtccagt tggcggcggt cgcgcttggt cggtctgccg
    14701 tcgggatagg cggaagtgat gcggctgaat tggtcgagct gtttgcgctc ttccctcaat
    14761 gttgctgttt tcgtgtcttc ttcatacaga agtcgcgcct cggatgccgg gcggcgttgg
    14821 tggttcaaac ctttaacctt gattttatag ggaagggaat tgagcgtcag gtcgataata
    14881 tcgccgatgt ctatggtttt actgtttttg accttcgagc cgtttacttg aaccctaccc
    14941 agttcgatgt gcttttgcgc aagggaacgg gtcttgaaaa aacgtgccgc ccaaagccat
    15001 ttgtccagcc gcatggcgga agaatggtgc ttgtctttca tacgattttg tttgaaataa
    15061 ttgaatttgt ttcgagttta gcataagata cgccgcctat aactagtata tatgcactaa
    15121 tccactgttt tccatgctgt ccgaacacaa aaagagggtg tggaaaagcc gttttggaca
    15181 ataaattaac tgcggaatat gcacaaatag cgtatgatag cggcagaatc tgttgatgag
    15241 agcttcattc tatgaaacct gtttttttgg attttgaaca acccatagcc gaactgacca
    15301 acaaaatcga tgagctgcgt ttcgtccaag acgagtctgc cgtcgatatt tcggacgaaa
    15361 tacaccgttt gcagaaaaaa agcaacgacc tgaccaaatc gattttcagc aaacttacgc
    15421 ccgcccaggt ttcacaggtt tcccggcatc cgcagcgtcc ctatactttg gattacattg
    15481 aggcactgtt taccgatttt gaagaactgc acggcgaccg ccactttgcc gacgatcatg
    15541 cgattgtcgg cggattggcg cgtttcaacg gacaaagcgt gatggtcgtc gggcatcaga
    15601 aagggcgcga caccaaagaa aaaatccgcc gcaacttcgg tatgccccgt cctgaaggct
    15661 accgcaaagc cctgcgcctg atgaaaacgg ctgagaaatt cggcttgccc gtcatgacct
    15721 ttatcgatac accgggcgcg tatcccggca tcggcgcgga agaacgcggg cagtcggaag
    15781 ccatcggcaa aaacctgtac gaactgacac gcctgcgcgt tcctgttttg tgtaccgtca
    15841 tcggcgaagg cggttcgggc ggtgcgttgg cggtcgccgt gggcgattac gtcaatatgc
    15901 tgcaatactc gacctattcc gttatttccc ccgaaggctg cgcttcgatt ttgtggaaaa
    15961 ccgccgaaaa ggcggcggat gcggctcagg ctttgggcat tactgctgac cgcctgcaaa
    16021 agctggactt ggtcgatacc gtcatcaaag aaccattggg cggcgcgcat cgggattttg
    16081 ggcaaaccat gaaaaacgtg aaagccgttt tggaaaaaca actgcacgaa gcgcaaagca
    16141 tcccgcttgc cgatttgctt tcgcgccgtt tcgaccgcat tatggcttac ggcaaatttt
    16201 cggaacaata attcaggtag aacaagcagc aagcagtttg tctgaaactg cttgcttttt
    16261 ctttatcggg acggaaccgt gctgacttta gatgcgtttg agcaatgctt gaaggattgt
    16321 tttcctcaag gtctgaatgg aaaaaaaaca gcggtggcat taagcggcgg cttggattcc
    16381 gtcgttttgc tgcatctgct tgtccgcgcc gggaaaaaag gcggttttat tccgaatgca
    16441 ttgcatatcc atcacggctt gagtccccgt gccgacgatt gggcagattt ctgccaaaac
    16501 tattgcgata tgctcggggt ggggctggaa acggttaagg tctgcgtgga aaaaaacggt
    16561 ttgggcatcg aggcggcggc aagacaaaag cgttatgccg cgtttgccga aaaaggcttt
    16621 gacgttttgg cgttggcgca ccacagggac gatcaaatcg aaacttttat gctggcggtc
    16681 gcgcgcggcg gcggtttgcg cgctttggcg gctatgcccg ccgtccgccc ttttggggaa
    16741 aaaggcatca tctggcggcc cttgctgcct ttttcgcgcc aagatatatg ggattatgcc
    16801 caaaaacacg gtttgctgaa tatcgaggat gaaagcaata ccgatacggc ttatttgcga
    16861 aaccgcttcc ggcaccgtat tttgcccgaa ctttcggcgc agattcccca tttcgggcgg
    16921 catgtgctga acaatgtccg cgctttgcag gaagatttgg ctttgttgga cgaggtcgtc
    16981 gttcaggact gccgttgggt ttgcggggcc ggttatttcg atacggcgcg gtggctgacg
    17041 ttttccccgc gccggaaaac ccatattttg cggcattttc tgaaggaaaa cggcattccc
    17101 gtgccgaatc agaatgccct tgccgacatt gcccgggttt tgacggaggc aaaaaccgga
    17161 cgttggaacg tgcaaggctt tgaattgcat cattatgcag gcaggctgtt tgtgttccga
    17221 ctggaaaaaa cggataaact gcggtttttg aaagacaggc agataagcgg aaatttgagg
    17281 gaaatattga cgaggcaggg atttgttttg aaacgtcatc cgttcgggct tcccgggcat
    17341 cttttggagc aggacgggat tttgcgagcg gtagcagcat cggatacgtt ggctgtcggc
    17401 ggcatccata aggatgtgaa aaaaatcctt caggaaaaac gggttttgcc cgtgctgcgc
    17461 ccgttttggc cggtcgtcgc cgacaaggac aaccgtccgc tggtgttggc aaattacggt
    17521 acggattttc aaatctcggt ttcagacggc attttgcccg tccatcctga ctttcccatt
    17581 ttattttgat aatatcgcaa acagattttg gcggcgttca gtcgggtatt gtccggttgc
    17641 atatttctaa aaggcttgtg aagtgaaaca catcagttcg accaataatg aacacatcag
    17701 acacctgcac cacctgttgt cgcaaggaaa gttcagacgg caatacgccc aatccgtttt
    17761 ggagggcgtg cacctgcttc aggttttcct gcaatccggc agaaaaccgg tcggggtata
    17821 tattcccgaa gctaaaatgc cgtctgaaga agcccgtaaa ttgacagcag ttttgccgga
    17881 agacaggatt ttttccgttt cagacggcat attgaaaaaa atcagcagct tgagttgtgc
    17941 agacgatata cttgcactga ttgatatccc attgggcgga accttgccgg acaaaggcga
    18001 ctgtgtggtt ttggacggcg tgcaagaccc gggcaatgtc ggcacggtgt tgcggagcgc
    18061 ggcggcggcg ggaatcggcg tggtcgtttt gggcaaaggt tgcgcggacg cgtggtcgcc
    18121 caaggtatta cgcgcgggga tgggcgcgca tttcttgttg gacatttatt cgcaggcgga
    18181 tttggaaata tggttggcga gctataaagg ccgtgtgttt gccaccgcct tgcgagagga
    18241 aaagcaggcg gttttgtacg gcgaagattt gtgcgaaccg acagcctggg tgtttggcaa
    18301 cgaaggcgcg ggggtcggta aagcggtttt ggacagggcg gacaagtgtg tcaggattcc
    18361 gatgcacgat gcaaccgagt ctttaaatgt cgcgatggcg gcgacaatct gcctgtttga
    18421 acagatgcgg cagcggtcgg cgtattgagg aaaagaaatg ccgtctgaaa aaatctatta
    18481 cggcgtattg attttcttat gtatcgcttc tatgctgctg tcgccgtttt tttatgcggg
    18541 tgctttgaag cccaagaagg cggcattgcg gaaggacggg cagtggaaac tcatcttatt
    18601 gtccaatacc gtggcggcgg cggttttgtt ttggatgtgg tggaaatggt tttgacagat
    18661 attgctcaaa attgggttaa tggaatccga acaaataaat aatttggtaa aaaatttgtt
    18721 aaatcaatgg attaaagttt ttcgggaaac aaaacagctc taagcaaata gggcgtttgt
    18781 cggtaaatac ggaagagttg cggcattatc gggcatcttt aacaagtagt gccggcttgg
    18841 caggcaattg gtttttatgg gcagcttgca aaatcgcgga tataaaattg cgaatcggtt
    18901 aaagtgtggg gacgctatga aaaattgcga atttttttat gacccgacaa gggcaatcta
    18961 tgatagcggt gcagattatt taaccagaga aaaacata
//
LOCUS       DAXIDM010000034        18937 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000034 DAXIDM010000000
VERSION     DAXIDM010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18937
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.034"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..79)
                     /locus_tag="ACFOAE_000960"
     CDS             complement(<1..79)
                     /locus_tag="ACFOAE_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-fructose-6-phosphate
                     aminotransferase"
                     /protein_id="HFC6884468.1"
                     /translation="MKPAVWAALLLCACTSNFGDREHQFL"
     gene            282..1610
                     /gene="miaB"
                     /locus_tag="ACFOAE_000961"
     CDS             282..1610
                     /gene="miaB"
                     /locus_tag="ACFOAE_000961"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HFC6884469.1"
                     /translation="MKKVFIRTFGCQMNEYDSDKMLAVLAEEHGGIEQVTQADEADII
                     LFNTCSVREKAQEKVFSDLGRVRPLKEKNPGLIIGVAGCVASQEGENIIKRAPYVDVV
                     FGPQTLHRLPKMIVDKETSGLSQVDISFPEIEKFDHLPPARVEGGAAFVSIMEGCSKY
                     CSFCVVPYTRGEEFSRPLNDVLTEIANLAQQGVKEINLLGQNVNAYRGEMDDGEICDF
                     ATLLRIVHEIPGIERMRFTTSHPREFTDSIIECYRDLPKLVSHLHLPIQSGSDRVLSA
                     MKRGYTALEYKSIIRKLRAIRPDLCLSSDFIVGFPGETEREFEQTLKLVKDIAFDLSF
                     VFIYSPRPGTPAANLHDDTPHEEKVRRLEALNEVIEAETARINQTMIGTVQRCLVEGI
                     SKKDPDQLQARTANNRVVNFTGTPDMINQMIDLEITEAYTFSLRGKVVEA"
     gene            complement(1695..3608)
                     /gene="dxs"
                     /locus_tag="ACFOAE_000962"
     CDS             complement(1695..3608)
                     /gene="dxs"
                     /locus_tag="ACFOAE_000962"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFC6884470.1"
                     /translation="MNPSPLLDLIDSPQDLRRLDKKQLPRLAGELRAFLLESVGQTGG
                     HFASNLGAVELTIALHYVYNTPEDKLVWDVGHQSYPHKILTGRKNQMHTMRQYGGLAG
                     FPKRCESEYDAFGVGHSSTSIGAALGMAAADKLLGSDRRSVAIIGDGAMTAGQAFEAL
                     NCAGDMDVDLLVVLNDNEMSISPNVGALPKYLASNVVRDMHGLLSTVKAQTGKVLDKI
                     PGAMEFAQKVEHKIKTLAEEAEHAKQSLSLFENFGFRYTGPVDGHNVENLVDVLKDLR
                     SRKGPQLLHVITKKGNGYKLAENDPVKYHAVANLPKESAAQMPSEKEPKPAAKPTYTQ
                     VFGKWLCDRAAADSRLVAITPAMREGSGLVEFEQRFPDRYFDVGIAEQHAVTFAGGLA
                     CEGMKPVVAIYSTFLQRAYDQLVHDIALQNLPVLFAVDRAGIVGADGPTHAGLYDLSF
                     LRCIPNMIVAAPSDENECRLLLSTCYQADAPAAVRYPRGTGTGVPVSDGMETVEIGKG
                     IIRREGGKTAFIAFGSMVAPALAVAGKLNATVADMRFVKPIDEELIVRLARSHDRIVT
                     LEENAEQGGAGGAVLEVLAKHGICKPVLLLGVADTVTGHGDPKKLLNDLGLSAEAVER
                     RVRAWLSDRDAAN"
     gene            complement(3693..4610)
                     /gene="xerC"
                     /locus_tag="ACFOAE_000963"
     CDS             complement(3693..4610)
                     /gene="xerC"
                     /locus_tag="ACFOAE_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFC6884471.1"
                     /translation="MVLDGFAAHFDAYLENIVREGKSEHTVAAYRRDLEELFALLAQM
                     PSEDAGGVPQDLSRRDFTAALRRLSQRGLNARTLARKLSSWRQYCVWLVERGLLHTDP
                     TADIKPPKQPERVPKALPQEWLNRMLDLPVDGGDPLAVRDHALFELMYGSGLRVSEIH
                     GLNADDVYLDEAWVHVTGKGRKQRQVPLTGKSVEALKNYLPLRQTASDGKALFTGRNG
                     TRLSQRQIQKRLAQWAAQNGDGRHVSPHMMRHSYAGHLLQASRDIRAVQELLGHSSLS
                     TTQIYTKLDFDHIARLYDEAHPRAKRQDE"
     gene            4804..5868
                     /gene="fba"
                     /locus_tag="ACFOAE_000964"
     CDS             4804..5868
                     /gene="fba"
                     /locus_tag="ACFOAE_000964"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219833.1"
                     /note="catalyzes the reversible aldol condensation of
                     dihydroxyacetonephosphate and glyceraldehyde 3-phosphate
                     in the Calvin cycle, glycolysis, and/or gluconeogenesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFC6884472.1"
                     /translation="MALVSMRQLLDHAAENSYGLPAFNVNNLEQMRAIMEAADQVNAP
                     VIVQASAGARKYAGAPFLRHLILAAVEEFPHIPVVMHQDHGASPDVCQRSIQLGFSSV
                     MMDGSLMEDGKTPSSYEYNVNATRTVVNFSHACGVSVEGEIGVLGNLETGEAGEEDGV
                     GAVGKLSHDQMLTSVEDAVRFVKDTGVDALAIAVGTSHGAYKFTRPPTGDVLRIDRIK
                     EIHQALPNTHIVMHGSSSVPQEWLKVINEYGGNIGETYGVPVEEIVEGIKHGVRKVNI
                     DTDLRLASTGAVRRYLAENPSDFDPRKYLSKTIEAMKQICLDRYLAFGCEGQAGKIKP
                     VSLEKMASRYAKGELNQIVK"
     gene            5888..6865
                     /locus_tag="ACFOAE_000965"
     CDS             5888..6865
                     /locus_tag="ACFOAE_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="factor H-binding protein"
                     /protein_id="HFC6884473.1"
                     /translation="MPSEPLFGRHLIFASLTCLIDAVCKKRYHNQNVYILSILRMTRS
                     KPVNRTTFCCLSLTTALILTACSSGGGGSGGGGVAADIGAGLADALTAPLDHKDKGLQ
                     SLTLDQSVRKNEKLKLSAQGAEKTYGNGDSLNTGKLKNDKISRFDFIRQIEVDGQLIT
                     LESGEFQVYKQSHSALTALQTEQEQDPEHSEKMVAKRRFKIGDIAGEHTSFDKLPKDV
                     MATYRGTAFGSDDAGGKLTYTIDFAAKQGHGKIEHLKSPELNVDLAAADIKPDEKHHA
                     VISGSVLYNQDEKGSYSLGIFGGQAQEVAGSAEVETANGIQHIGLAAKQ"
     gene            7004..7681
                     /gene="tsaB"
                     /locus_tag="ACFOAE_000966"
     CDS             7004..7681
                     /gene="tsaB"
                     /locus_tag="ACFOAE_000966"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFC6884474.1"
                     /translation="MQADFNRPVLAVDTGTSHLSLALRADGETRLFHQEVGSRQSELI
                     LPEIRTLFRNAGITAADLGAIVYAKGPGAFTGLRIGIGVAQGLATPFDTPLIGIPTLD
                     AAASLPPPQSCILAAADARMGEVFYAWFDTLNRRRLSDYQVGRAADIRLPEGCAFSDG
                     IGSAFALEETPPFSGKPDMPTAADFLNLAAEGGFPAVAAAHAELLYVRNKIALTAKEQ
                     AERRARL"
     gene            7678..8118
                     /gene="rimI"
                     /locus_tag="ACFOAE_000967"
     CDS             7678..8118
                     /gene="rimI"
                     /locus_tag="ACFOAE_000967"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFC6884475.1"
                     /translation="MNIRRAVYADCAALAALDAVCNPSAWTQRQFESALVSLSEQVFL
                     AEKDGGLAAFIVWQNLPDESELHLIATAPECRRQGIASALLEYWFAHLPEGTQRLLLE
                     VRAGNTAAQALYAAHGFSIAGRRKNYYRATDGQTEDAVLMEKIC"
     gene            8112..8849
                     /locus_tag="ACFOAE_000968"
     CDS             8112..8849
                     /locus_tag="ACFOAE_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010791194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HFC6884476.1"
                     /translation="MLSARYLHLHEALGLGPMWLKQAAAVLPPKNTPATPAQARPQTV
                     RAAPIRPSQPHNGQARLETMKALETAAVPTRKPAPETETPLPGLSDGIAPVPAASGIT
                     KLAVVSLCPPIEDAVYGQLFHGKAGVLLDNILKAVGLDAAYVHKTCWVKTAAVGNPMP
                     SEQAVANALGQIARELDGCRAPAVLFLGQAFVQPERQTMIETLCGSRPFFIIDHPARL
                     LRQPELKARAWQVLKQLKRALRQGGGS"
     gene            8911..9552
                     /gene="pyrE"
                     /locus_tag="ACFOAE_000969"
     CDS             8911..9552
                     /gene="pyrE"
                     /locus_tag="ACFOAE_000969"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFC6884477.1"
                     /translation="MTDFRQDFLKFSLAQNVLKFGEFTTKAGRRSPYFFNAGLFNDGL
                     STLQLAKFYAQSIIESGIRFDMLFGPAYKGIILAAATAMMLAEKGVNVPFAYNRKEAK
                     DHGEGGVLVGAPLKGRVLIIDDVISAGTSVRESIKLIEAEGATPAGVAIALDRMEKGT
                     GELSAVQEVEKQYGLPVAPIASLNDLFILLQNNPEFGQFLEPVRAYRRQYGVE"
     gene            9626..10060
                     /locus_tag="ACFOAE_000970"
     CDS             9626..10060
                     /locus_tag="ACFOAE_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MJ0042-type zinc finger domain-containing
                     protein"
                     /protein_id="HFC6884478.1"
                     /translation="MPACFCPHCKTRLWVKETQLNVAQGFVVCQKCEGLFKAKDHLAS
                     TKEPIFNDLPEAVSDVKLVHRIGTRAIGKKQISRDEIAGILNGGTTQPDIPPATAATP
                     AAAPQVTVPPAAPARQDGFNWTIATLFALIVLIMQLSYLVIL"
     gene            10057..11367
                     /gene="argA"
                     /locus_tag="ACFOAE_000971"
     CDS             10057..11367
                     /gene="argA"
                     /locus_tag="ACFOAE_000971"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HFC6884479.1"
                     /translation="MIVPDLFVAHFREAAPYIRQMRGKTLVAGIDDRLLEGDTLNKLA
                     ADIGLLSQLGIRLVLIHGARHFLDRHAAAQGRTPHYCRGLRVTDETSLEQAQQFAGTV
                     RSRFEAALCGSVSGFARAPSVPLVSGNFLTARPIGVIDGTDMEYAGVIRKTDTAALRF
                     QLDAGNIVWLPPLGHSYSGKTFHLDMLQTAASVAVSLQAEKLVYLTLSDGISRPDGTL
                     AVTLSAQEAQSLAEHAGGETRRLISSAVAALEGGVHRVQILNGAADGSLLQELFTRNG
                     IGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLHRSREYLENHISEFSILEHD
                     GNLYGCAALKTFAEADCGEISCLAVSPQAQDGGYGERLLAHIIDKARSMGISRLFALS
                     TNTGEWFAERGFQTASEDELPETRRKDYRSNGRNSHILVRRLHR"
     gene            11463..13478
                     /locus_tag="ACFOAE_000972"
     CDS             11463..13478
                     /locus_tag="ACFOAE_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family protein"
                     /protein_id="HFC6884480.1"
                     /translation="MKSYPDPYRHFENLDSAETQNFAAEANAETRARFLNNDKARALS
                     DGILNQMQDTRQIPFCQEHRARMYHFHQDAEYPKGVYRVCTAATYRSGYPEWKILFSV
                     ADFDELLGDDVYLGGVSHLVEKPNRALLTLSKSGGDTAYTLEVDLEAGELVEGGFHFP
                     AGKNQVSWRDENSVWVCPAWDERQLTESGYPREVWLVERGKSFEESLPVYQIDKDAMM
                     VNAWRYLDPQGSPIDLIEASDGFYTKTYLQVSAEGEAKPLNLPNDCDVVGYLAGHLLL
                     TLRKDWNRANQSYPSGALVAVKLNRGELGAAQLLFAPDETQALESVETTKRFVVASLL
                     ENVQGRLKAWRFADGKWQEVELPRLPSGALEMTDQPWGGDVVYLAAGDFTTPLTLFAL
                     DLNVMELTVMRRQPQQFDSDGIEVRQFWVMSSDGERIPYFHVGKNAAPDTPTLVYAYG
                     GFGVPELPHYLGSIGKYWLEEGNAFVLANIRGGGEFGPRWHQAAQGISKHKSVDDLLA
                     VVRDLSERGISSPQHIGLQGGSNGGLITAAAFVREPQSIGALVCEVPLTDMIRYPLLS
                     AGSSWTDEYGNPQKYEVCKRRLGELSPYHNLSDGIDYPPALITTSLSDDRVHPAHALK
                     FYAKLRETSPQSWLYSPDGGGHTGNGTQREAADELACVLLFLKEFLG"
     gene            complement(13592..14548)
                     /locus_tag="ACFOAE_000973"
     CDS             complement(13592..14548)
                     /locus_tag="ACFOAE_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC6884481.1"
                     /translation="MNTAAIYRQYQTYVRSDKSGWALDGCSDSALIAQAKQPGLHLEM
                     CINRFDSGITLSRMRGGGTGAFPTEIHNFSHNCALFVMVSGQNRLQMGGREYRPSAGE
                     IWLVRGELADVSETLLPDNSGMCALHLDFSLEKLRRWHDEGLLDERLFSPQTIGRFAL
                     QRLAQNAAALTAAACPLLQRPFESDGFGLLADEAAALELSARLLRFTFRRHDNGYRRR
                     RIDEAADILQHEFARPLTIAEIARRVGLNECYLKRYFKAQTGETVAGCLRRLRLEHAL
                     ALIESGSTVQAAMHFCGYRHAGRFNEAFRRHYGFLPSDVKKC"
     gene            14784..15749
                     /locus_tag="ACFOAE_000974"
     CDS             14784..15749
                     /locus_tag="ACFOAE_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6884482.1"
                     /translation="MKPRFYWAACAVLLTACSPEPAAEKTVSAASASAATLTVPTARG
                     DAVVPKNPERVAVYDWAALDTLTELGVNVGATTAPVRVDYLQPAFDKAATVGTLFEPD
                     YEALHRYNPQLVITGGPGAEAYEQLAKNATTIDLTVDNGNIRTSGEKQMETLARIFGK
                     EARAAELKAQIDALFAQTREAAKGKGRGLVLSVTGNKVSAFGTQSRLASWIHGDIGLP
                     PVDESLRNEGHGQPVSFEYIKEKNPDWIFIIDRTAAIGQEGPAAVEVLDNALVRGTNA
                     WKRKQIIVMPAANYIVAGGSRQLIQAAEQLKAAFEKAEPVAAGKE"
     gene            complement(16111..16248)
                     /locus_tag="ACFOAE_000975"
     CDS             complement(16111..16248)
                     /locus_tag="ACFOAE_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884483.1"
                     /translation="MASFSGRSCNESVIDFDASLRLTALSLTLSHRERGRVAVASLFA
                     A"
     gene            16294..16617
                     /locus_tag="ACFOAE_000976"
     CDS             16294..16617
                     /locus_tag="ACFOAE_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003775941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFC6884484.1"
                     /translation="MQNETINLKQHLAAIKEYWQPEIINRHGFQFRLVKLLGDYGWHT
                     HGYSDKVLFAVEGDMAVDFADGGSMTIREGEMAVVPKSVSHRPRSENGCSVVLIELSD
                     PSEAV"
     gene            16731..18908
                     /gene="tdfF"
                     /locus_tag="ACFOAE_000977"
     CDS             16731..18908
                     /gene="tdfF"
                     /locus_tag="ACFOAE_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010950972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent iron piracy receptor TdfF"
                     /protein_id="HFC6884485.1"
                     /translation="MTRFKYSLLFAALLPVYAQADVSVSDDPKPQESTELPTITVTAD
                     RTASSNDGYTVSGTHTPLGLPMTLREIPQSVSVITSQQMRDQNIKTLDRALLQATGTS
                     RQIYGSDRAGYNYLFARGSRIANYQINGIPVADALADTGNANTAAYERVEVVRGVAGL
                     LDGTGEPSATVNLVRKRPTRKPLFEVRAEAGNRKHFGLGADVSGSLNAEGTLRGRLVS
                     TFGRGDSWRQRERSRDAELYGILEYDIAPQTRVHAGMDYQQAKETADAPLSYAVYDSQ
                     GYATAFGPKDNPATNWANSRHRALNLFAGIEHRFNQDWKLKAEYDYTRSRFRQPYGVA
                     GVLSIDHNTAATDLIPGYWHADPRTHSASVSLTGKYRLFGREHDLIAGINGYKYASNK
                     YGERSIIPNAIPNAYEFSRTGAYPQPSSFAQTIPQYGIRRQIGGYLATRFRAADNLSL
                     ILGGRYSRYRTGSYDSRTQGMTYVSANRFTPYTGIVFDLTGNLSLYGSYSSLFVPQSQ
                     KDEHGSYLKPVTGNNLEAGIKGEWLEGRLNASAAVYRARKNNLATAAGRDPSGNTYYR
                     AANQAKTHGWEIEVGGRITPEWQIQAGYSQSKTRDQDGSRLNPDSVPERSFKLFTAYH
                     FAPEAPSGWTIGAGVRWQSETHTDPATLRIPNPATKARAADNSRQKAYAVADIMARYR
                     FNPRAELSLNVDNLFNKHYRTQPDRHSYGALRTVNAAFTYRFK"
BASE COUNT         4246 a         5896 c         5162 g         3633 t
ORIGIN      
        1 gcaggaactg atgttccctg tcgccaaaat tgctggtaca cgcacacagc agcaatgccg
       61 cccacacagc cggtttcata cacacctccc attaaagcca aacattatac agccgtcctg
      121 accgattaaa ttcatatttt aaaacaatat cctgcctcca aaacccacat cgtgctataa
      181 tccacaccga ttttcagacg gcatcgtcat gccgtctgaa attttttcat tccaacaaca
      241 atcagccccg cgattacggc tgcctgagaa agacacaaac catgaaaaaa gtatttatcc
      301 gtaccttcgg ctgccagatg aacgaatacg acagcgacaa aatgctcgcc gtcctcgccg
      361 aagaacacgg cggcatcgaa caggttaccc aagccgacga agccgacatc atcttgttca
      421 acacctgctc cgtgcgcgaa aaagcacagg aaaaagtgtt ctccgatttg gggcgcgtgc
      481 gtccgctcaa agaaaaaaac cccggcctca tcatcggcgt tgccggctgc gtcgcctcgc
      541 aagaaggcga aaacatcatc aaacgcgcgc cttatgttga cgtggtcttc ggcccgcaaa
      601 cgctgcaccg cctgcccaaa atgattgtgg acaaagaaac cagcgggctg tcgcaagtcg
      661 atatttcctt ccccgaaatc gaaaaattcg accacctgcc gcccgcccgc gtcgaaggcg
      721 gcgcggcatt tgtatcgatt atggaaggct gttccaaata ctgctcattc tgcgtcgtcc
      781 cctacacgcg cggcgaagaa ttctcccgcc cgctcaacga cgtattgaca gaaatcgcca
      841 accttgccca gcaaggcgtg aaagaaatca acctcttggg acaaaacgtc aacgcctatc
      901 gcggcgaaat ggacgacggc gaaatctgcg acttcgccac cctgctgcgc atcgtccacg
      961 aaatccccgg catcgaacgt atgcgcttca ccaccagcca cccgcgcgag tttaccgact
     1021 cgattatcga gtgctaccgc gacctgccca aattggtttc ccacctgcac ctgccgattc
     1081 aaagcggttc cgaccgcgta ttgagcgcga tgaaacgcgg ctacaccgct ttggaataca
     1141 aatccatcat ccgcaaactg cgtgccatcc gtcctgattt atgcctgagc agcgatttca
     1201 tcgtcggctt ccccggcgag accgaacgcg agttcgagca aaccttgaaa ctggtgaaag
     1261 acatcgcctt cgacttgagc ttcgtgttta tttacagtcc gcgccccggc acgcctgccg
     1321 ccaacctgca cgacgacacg ccgcacgaag aaaaagtgcg ccgcctcgaa gccttgaacg
     1381 aagtcatcga agccgaaacc gcgcgcatca accaaaccat gatcggcacg gttcaacgct
     1441 gcctggtcga aggcatctcc aaaaaagacc ccgaccaact gcaagcccgt accgccaaca
     1501 accgcgtcgt caacttcacc ggcacgcccg acatgattaa ccaaatgatc gatttggaaa
     1561 tcaccgaggc ctacaccttc tccctgcgcg gcaaagttgt cgaagcctaa accctcacgc
     1621 cgaaaaaatg ccgtctgaag cgtttcagac ggcattttgc cttgtatcgg cagacgacgg
     1681 cgcggccggg cggcttaatt tgccgcatcc cgatccgaca gccacgcgcg cacacgccgt
     1741 tccaccgctt cggcactcaa gcccaaatcg ttcaaaagtt ttttcggatc gccgtgtccg
     1801 gttacggtat cggcaacgcc caaaagcaaa acgggtttgc agatgccgtg tttcgccaat
     1861 acttccagca ccgcgccgcc tgcgccgccc tgttcggcgt tttcttcaag ggtaacgatg
     1921 cggtcgtggc ttcgggcaag gcggacaatc aactcttcgt ctatcggttt gacgaagcgc
     1981 atatcggcga cggtggcgtt cagttttccg gcaaccgcca atgcgggggc gaccatactg
     2041 ccgaaggcaa tgaatgcggt tttcccacct tcgcggcgga taatgccctt gccgatttcc
     2101 acggtttcca tgccgtctga aaccggcacg cccgtacccg tgccgcgcgg atagcggacg
     2161 gcggcgggcg cgtctgcctg atagcaggtc gaaagcagca ggcggcattc attttcatcg
     2221 ctcggcgcgg cgacaatcat attcggaatg cagcgcaaaa agcttaaatc gtacaaaccg
     2281 gcatgggtcg ggccgtccgc gccgacgatg cccgcgcggt cgacggcaaa caaaacgggc
     2341 aggttttgca gggcgatgtc gtgcaccagt tggtcgtagg cgcgttgtaa aaaggtggaa
     2401 taaatcgcca cgacgggctt catcccttcg caagccaaac cgccggcaaa ggtaacggcg
     2461 tgctgctcgg cgatgccgac atcgaaatag cggtcgggga atcgttgttc aaactcaacc
     2521 aagccgctgc cctcgcgcat ggcgggggta atcgcaacca gtcgggaatc tgccgccgcc
     2581 cggtcgcaca gccatttgcc gaacacttgg gtataggtcg gtttggcggc gggcttgggt
     2641 tctttttcag acggcatttg cgccgcgctt tctttaggca ggttggcgac ggcgtggtat
     2701 ttgacgggat cgttttcggc gagtttgtag ccgttgccct ttttggtgat gacgtgcagc
     2761 agttgagggc ctttgcggct gcgcaagtct ttcaatacgt ccaccagatt ttcgacgttg
     2821 tgtccgtcca cggggccggt gtagcggaag ccgaagtttt caaacaaaga cagcgactgt
     2881 ttggcgtgtt cggcttcttc ggcaagggtt ttgattttgt gttcgacttt ttgggcaaac
     2941 tccatcgcgc cgggtatttt gtctaatacc ttgcccgttt gcgctttgac ggtactcaac
     3001 aggccgtgca tatcgcgcac gacgttgctg gcgaggtatt tcggcagcgc gccgacgttg
     3061 ggggaaatcg acatttcgtt gtcgttgagg acgaccagca aatccacatc catatcgcct
     3121 gcgcaattca aggcttcaaa cgcctgcccc gccgtcatcg cgccgtcgcc gatgatggcg
     3181 acgctgcggc ggtcgctgcc caagagtttg tctgccgccg ccatgcccaa cgccgcgccg
     3241 atggaggtgg aggaatgccc cacgccgaac gcgtcgtact cggactcgca acgtttcgga
     3301 aaacccgcca aaccgccgta ttggcgcatg gtgtgcatct ggtttttgcg tccggtaagg
     3361 attttgtgcg gatagctttg gtgtccgaca tcccacacca gcttgtcttc gggcgtgttg
     3421 tacacatagt gcagggcgat ggtcagctcg accgcaccta agttgctggc gaaatgaccg
     3481 ccggtttgac cgacggattc cagcagaaag gcgcgcaact cgccggcaag gcgcggcagc
     3541 tgttttttgt ccagacggcg caaatcttgc gggctgtcaa tcaggtcgag tagggggctt
     3601 gggttcatgg tgtgtctttt ttatgtgtcg tccgggtgca acggccaatt atatatcaag
     3661 agtgtgcggc tgacggctga ttttgccgta tgtcattcgt cctgccgctt ggcgcgcggg
     3721 tgggcttcgt catacaggcg ggcgatgtgg tcgaaatcga gtttggtgta aatctgcgtg
     3781 gtcgaaaggc tgctgtgccc gagcagctcc tgcaccgccc tgatgtcgcg cgaagcctgc
     3841 aacaggtgtc cggcgtagct gtggcgcatc atatgcggcg aaacgtgcct gccgtcgccg
     3901 ttttgcgccg cccattgcgc caaacgtttt tggatttggc gttggctcag gcgcgtgccg
     3961 ttcctgccgg taaacagggc tttgccgtcc gatgccgtct gacgcagcgg cagatagttt
     4021 ttcagggctt ccacgctttt gccggtcagc ggcacctgcc gctgcttgcg ccctttgccg
     4081 gtaacgtgta cccacgcctc gtccaaatag acatcatctg cattcaagcc gtgtatctcg
     4141 ctcacgcgca aaccgctgcc gtacatcagt tcgaacagag cgtggtcgcg caccgccagc
     4201 gggtcgccgc cgtccacggg caaatccagc atccggttca gccattcctg cggcagggct
     4261 ttgggtacgc gctcgggctg cttcggcggt ttgatgtcgg cggtcgggtc ggtatgcagc
     4321 agaccgcgtt ccaccagcca aacacaatac tgccgccaag acgacagctt gcgcgccagc
     4381 gtccgcgcat tcaaaccgcg ctgcgacagc cgccgcaacg ccgccgtaaa atcgcgccgc
     4441 gacaagtcct gcggcacgcc gcctgcatct tcagacggca tttgtgccaa cagcgcaaac
     4501 agttcttcca aatcgcgccg gtatgccgcc accgtgtgct ccgacttgcc ctcgcgcacg
     4561 atgttttcca aataagcgtc aaaatgcgcc gcaaacccgt ccaaaaccat aaccgcccca
     4621 cacaaatatc aaaaaaacag tgaaaacatt atcataaacg acacaccaaa accccgaacc
     4681 gcccaaaatc cgacccgtcc gcccgccgtt atcgttaaca taaaatcaat gagccgttta
     4741 tggttttttg ccgcaaaaaa cattataatc cgccttattt acctattgcc caaggagaca
     4801 caaatggcac tcgtatccat gcgccaactg cttgatcatg ctgccgaaaa cagctacggc
     4861 ctgcccgcgt tcaacgtcaa caacctcgaa caaatgcgcg ccattatgga agccgccgac
     4921 caagtcaacg cgcccgtcat cgtacaggcg agtgcaggtg cgcgcaaata tgcgggcgcg
     4981 ccgtttttgc gccacctgat tctggcggca gtcgaagaat ttccgcacat ccccgtcgtg
     5041 atgcaccaag accacggcgc atcgcccgac gtgtgccaac gctccatcca actgggcttt
     5101 tcctccgtga tgatggacgg ctcgctgatg gaagacggca aaaccccttc ttcttatgaa
     5161 tacaacgtca acgccacccg taccgtggtt aatttctccc acgcttgcgg cgtatccgtc
     5221 gaaggcgaaa tcggcgtgtt gggcaacctc gaaaccggcg aagccggcga agaagacggt
     5281 gtaggcgcag tgggcaaact ttcgcacgac caaatgctca ccagcgtcga agatgccgtg
     5341 cgtttcgtta aagataccgg cgttgacgca ttggcgattg ccgtcggcac cagccacggc
     5401 gcgtacaaat tcacccgtcc gcccacaggc gacgtgttgc gtatcgaccg catcaaagaa
     5461 atccaccaag ccctgcccaa tacacacatc gtgatgcacg gctccagctc cgttccgcaa
     5521 gaatggctga aagtcatcaa cgaatacggc ggcaatatcg gcgaaaccta cggcgtgccg
     5581 gttgaagaaa tcgtcgaagg catcaaacac ggcgtgcgca aagtcaacat cgataccgac
     5641 ttgcgccttg cttccaccgg cgcggtacgc cgctaccttg ccgaaaatcc gtccgacttt
     5701 gacccacgca aatacctgag caaaaccatt gaagcgatga aacaaatctg cctcgaccgc
     5761 tacctcgcgt tcggctgcga aggtcaggca ggcaaaatca aaccggtttc cttggaaaaa
     5821 atggcaagcc gttatgccaa gggcgaattg aaccaaatcg tcaaataaca ggttgcctgt
     5881 aaacaaaatg ccgtctgaac cgttgttcgg acggcatttg atttttgctt ctttgacctg
     5941 cctcattgat gcagtatgca aaaaaagata ccataaccaa aatgtttata tattatctat
     6001 tctgcgtatg actaggagca aacctgtgaa ccgaactacc ttctgctgcc tttctctgac
     6061 caccgccctg attctgaccg cctgcagcag cggaggcggc ggaagcggag gcggcggtgt
     6121 cgccgccgac atcggtgcgg ggcttgccga tgcactaacc gcaccgctcg accataaaga
     6181 caaaggtttg cagtctttga cgctggatca gtccgtcagg aaaaacgaga aactgaagct
     6241 gtcggcacaa ggtgcggaaa aaacttatgg aaacggcgac agcctcaata caggcaaatt
     6301 gaagaacgac aaaatcagcc gcttcgactt tatccgtcaa atcgaagtgg acgggcagct
     6361 cattaccttg gagagcggag agttccaagt gtacaaacaa agccattccg ccttaaccgc
     6421 ccttcagacc gagcaagaac aagatccaga gcattccgag aagatggttg cgaaacgccg
     6481 gttcaaaatc ggcgacatag cgggcgagca tacatctttt gacaagcttc ccaaagacgt
     6541 catggcgaca tatcgcggga cggcgttcgg ttcagacgat gctggtggaa aactgaccta
     6601 caccatagat ttcgccgcca agcagggaca cggcaaaatt gaacatttga aatcgccaga
     6661 actcaatgtt gacctggccg ccgccgatat caagccggat gaaaaacacc atgccgtcat
     6721 cagcggttcc gtcctttaca accaagacga gaaaggcagt tactccctcg gtatctttgg
     6781 cgggcaagcc caggaagttg ccggcagcgc ggaagtggaa accgcaaacg gcatacagca
     6841 tatcggcctt gccgccaagc agtaaccatt gtgaaaatgc cgtccgaaca caataattta
     6901 ccgttcggac ggcatttttg cgccataccg ccctaggaca cgacggcacg gcaggcaagc
     6961 cgatttcact atataatgcc gtctgaacca acgagagaat gccatgcaag ctgatttcaa
     7021 ccgccccgtc ctcgccgtcg ataccggtac ttcccatttg tcgctcgcgc tgcgtgctga
     7081 cggcgaaacc cgtctgttcc atcaggaagt cggcagccgc cagtccgaac tgattctgcc
     7141 ggaaatccgc actctattcc gaaatgcggg cattaccgcc gccgatttgg gggcgattgt
     7201 ttatgcgaaa ggccccggcg cgtttacggg actgcgtatc ggtatcggcg tggcgcaagg
     7261 tttggcaacg ccgtttgata cccctttaat cggcatcccc acgctcgatg ccgccgcctc
     7321 gctgccgccg ccgcaaagct gcatactcgc cgctgcggac gcgcgtatgg gcgaagtgtt
     7381 ttatgcgtgg ttcgacacgc tgaaccgccg ccgtttgagc gattatcagg tcgggcgggc
     7441 ggcagacatc cggctgccgg agggatgtgc cttttcagac ggcataggca gcgcgttcgc
     7501 gttggaagaa acgccgccgt tttcaggcaa acccgatatg ccgaccgccg ccgacttcct
     7561 caatctggcg gctgaaggcg gttttcccgc cgtcgctgcg gcacacgccg agctgctcta
     7621 cgtccgcaac aaaatcgccc tgactgccaa agaacaggcg gaacggaggg cgcgcctgtg
     7681 aacatccgcc gcgccgttta tgccgattgc gcggcactcg ccgcactcga tgccgtctgc
     7741 aacccgtccg cgtggacgca acgccaattt gagtctgcat tggtttcgct gtccgaacag
     7801 gttttcctcg cggaaaaaga cggcgggttg gccgccttta tcgtttggca gaacctgccc
     7861 gacgaatccg aactgcacct gattgccacc gcgcccgaat gccgccgcca aggaattgcg
     7921 tccgccctgc tcgaatattg gttcgcacat ctgcccgaag gcacgcaacg cctgctgctc
     7981 gaagtccgcg caggcaacac cgccgcgcag gcactgtacg cggcgcacgg cttcagcatt
     8041 gcgggcaggc ggaaaaacta ttaccgcgcc accgacgggc aaaccgaaga tgccgtctta
     8101 atggagaaaa tatgttaagc gcgcgctacc tccacctgca cgaagctttg ggtttgggtc
     8161 cgatgtggct gaaacaggcc gctgccgtcc tgccgcccaa aaacacaccc gcaaccccgg
     8221 cacaggcacg tcctcaaacc gtccgcgccg ccccgatccg cccttcccaa ccccataacg
     8281 gtcaggcgcg gctcgaaacg atgaaagcgt tggaaaccgc cgccgtacct acgcgcaaac
     8341 ccgcgcctga aaccgaaacg cctctgcccg gcctttcaga cggcatcgcc cccgttcccg
     8401 ccgcttcggg cataaccaaa cttgccgtcg tcagcctttg cccaccgatc gaggatgcgg
     8461 tttacgggca gctgttccac ggcaaagcgg gtgtcctgct tgacaacata ctcaaagccg
     8521 taggactgga tgccgcctat gtccacaaaa cctgttgggt gaaaaccgcc gccgtcggca
     8581 acccgatgcc gtctgaacag gccgtcgcga atgcgctggg tcaaatcgcc cgcgaactcg
     8641 acggctgccg cgccccggct gtcctattcc tcgggcaggc ttttgtccag cctgaacggc
     8701 aaacgatgat tgaaactttg tgcggcagcc gtcccttctt catcatcgac catcccgccc
     8761 ggctgttgcg ccaacccgaa cttaaagccc gcgcctggca ggtgttgaaa cagttgaaac
     8821 gcgccttgcg gcaaggcggc ggcagttgaa gcgcaccgca cggggcggta gaatcgcaac
     8881 tgcgtcccaa tatctgacag aaagcacaaa atgaccgatt tccgccaaga tttcctcaaa
     8941 ttctccctcg cccaaaatgt tttgaaattc ggcgaattta ccaccaaagc cggacggcgg
     9001 tcgccctatt tcttcaatgc cggcctcttt aacgacggct tgtccacgct gcaactggca
     9061 aaattttacg cacaatccat cattgaaagc ggcatccgat tcgatatgct gttcggcccc
     9121 gcctacaaag gcattatttt ggcggcggca accgcgatga tgctggcgga aaaaggcgtg
     9181 aacgtcccgt ttgcctacaa ccgcaaagaa gccaaagacc acggcgaagg cggcgtgttg
     9241 gtcggtgcgc cgcttaaagg ccgcgtgctg attatcgacg acgtgatttc cgccggcaca
     9301 tccgtacgcg aatcgatcaa gctgattgaa gcggagggcg caacccccgc cggtgtcgcc
     9361 atcgcgctcg atcgcatgga aaaaggcacg ggtgagttga gcgcggttca ggaagtggaa
     9421 aaacaatacg gtctgcccgt cgcccccatc gccagcctga acgatttgtt tattctgttg
     9481 caaaacaacc ccgaattcgg acagttcctc gaacccgtcc gagcctaccg tcggcagtac
     9541 ggcgtagaat aaaaacaaag catatgccgt ccgaaccgcc ttacgcctca gacggcatca
     9601 aacctgacac acacgaggaa ataccatgcc cgcctgtttc tgcccccact gcaaaacccg
     9661 tctctgggtc aaagaaaccc aactcaatgt cgcccaaggc ttcgtcgtct gccaaaaatg
     9721 cgaaggactg tttaaagcca aagaccatct ggcaagcacg aaagaaccca tattcaacga
     9781 tttgcccgag gctgtttcgg atgtcaaact cgttcaccgt atcggcacgc gcgccatcgg
     9841 caagaaacag atttcccgtg acgaaatcgc cggcatcctc aacggcggca caacccagcc
     9901 cgatattccg cccgcaaccg ccgccacccc tgctgccgca ccgcaggtta ccgtaccgcc
     9961 cgccgcgccc gcccgtcagg atgggttcaa ctggacgatt gcaaccctgt ttgcccttat
    10021 cgtcctcatt atgcagcttt cctacctcgt catcctatga tcgtgcccga cctctttgtc
    10081 gcccacttcc gcgaagccgc cccctacatc cgccaaatgc gcggcaaaac gctggtcgcc
    10141 ggcatagacg accgcctgct cgaaggtgat accttaaaca agctcgccgc cgacatcggg
    10201 cttttgtcgc aactgggcat caggctcgtc ctcatccacg gcgcgcgcca cttcctcgac
    10261 cgccacgccg ccgcgcaagg ccgcacgccg cattattgcc ggggcttgcg cgttaccgac
    10321 gaaacctcgc tcgaacaggc gcagcagttt gccggcaccg tccgcagccg ttttgaagcc
    10381 gcattgtgcg gcagcgtttc cgggttcgcg cgcgcgcctt ccgtcccgct cgtatcgggc
    10441 aacttcctga ccgcccgtcc gataggtgtg attgacggaa ccgatatgga atacgcgggc
    10501 gttatccgca aaaccgacac cgccgccctc cgtttccaac tcgacgcggg caatatcgtc
    10561 tggctgccgc cgctcggaca ttcctacagc ggcaagacct tccatctcga tatgcttcaa
    10621 accgccgcct ccgtcgccgt ctcgcttcag gccgaaaaac tcgtttacct gaccctttca
    10681 gacggcattt cccgccccga cggcacgctc gccgtaaccc tctcggcaca ggaagcgcaa
    10741 tcgctggcgg aacacgccgg cggcgaaacg cgacggctga tttcgtccgc cgttgccgcg
    10801 ctcgaaggcg gcgtgcatcg cgtccaaatc ctcaacggtg ccgccgacgg cagcctgctg
    10861 caagaactct tcactcgcaa cggcatcggc acgtccattg ccaaagaagc cttcgtctcc
    10921 atccggcagg cgcacagcgg cgacatcccg cacattgccg ccctcatccg cccactggaa
    10981 gaacaaggca tcctgctgca ccgcagccgc gaatacctcg aaaaccacat ttccgaattt
    11041 tccatcctcg aacacgacgg caacctgtac ggttgcgccg ccctgaaaac ctttgccgaa
    11101 gccgattgcg gcgaaatctc ctgccttgcc gtctcgccgc aggcacagga cggcggctac
    11161 ggcgaacgcc tgcttgccca cattatcgat aaggcgcgca gtatgggcat aagcaggctg
    11221 ttcgccctct ccacaaatac cggcgaatgg tttgccgaac gcggctttca gacggcatcg
    11281 gaagacgagt tgcccgaaac gcggcgcaaa gactaccgca gcaacggacg aaactcgcat
    11341 attctggtac gtcgcctgca ccgctgaccg caacggaaag ccgccgcaga aatgccgtct
    11401 gaaccccgtt tcagacggca tttccccgat tataaagacc tgcccaaccc tcaaggaccc
    11461 cgatgaaatc ctaccccgac ccctaccgcc attttgaaaa cctcgattcc gccgaaacgc
    11521 aaaacttcgc tgctgaagcg aatgccgaaa cgcgcgcgcg ttttttaaac aacgacaagg
    11581 cgcgcgcgct ttcagacggc attttgaatc aaatgcagga cacgcggcag attccgtttt
    11641 gtcaggaaca ccgcgcgcgg atgtaccatt tccatcagga cgcggaatat ccgaagggcg
    11701 tgtaccgcgt gtgcacggcg gcgacctacc gttcgggcta tccggagtgg aaaatcctgt
    11761 tttcagtggc ggacttcgac gaattgctcg gcgacgatgt atatttgggc ggcgtgtcgc
    11821 acttggtgga aaagcccaac cgcgcgttgt tgacactaag caaatcaggc ggcgatacgg
    11881 cgtacacgct ggaagtggat ttggaagcag gggaattggt agaaggtggt tttcactttc
    11941 cggcaggcaa aaaccaagtg tcgtggcgcg atgaaaacag cgtgtgggtg tgtccggctt
    12001 gggacgaacg ccagttgacc gaatcgggct atccgcgtga ggtgtggctg gtggaacgcg
    12061 gcaagagttt cgaggaaagc ctgcctgtgt atcaaatcga taaagatgca atgatggtga
    12121 acgcgtggcg ttatctcgat ccgcagggtt cgccgattga tttgattgaa gcgtcggacg
    12181 gtttttacac caaaacctat ttgcaggtgt cggccgaagg cgaggcgaaa ccgttaaacc
    12241 tgcccaacga ttgcgatgtg gtcggctatc tggcggggca tcttttgctg acgctgcgca
    12301 aggactggaa ccgcgcgaac caaagctatc cgagcggtgc gctggtggcg gtgaagctga
    12361 atcggggtga actcggggcg gcgcagcttt tgtttgcgcc tgatgaaacg caggcattgg
    12421 aaagcgtgga aacgaccaag cgttttgtgg tggcgagcct gctggaaaac gtacaaggcc
    12481 gtctgaaagc gtggcgtttt gccgacggca aatggcagga agtcgaactg ccgcgcctgc
    12541 cttcgggcgc gttggaaatg accgaccagc cttggggcgg cgacgtggtt taccttgccg
    12601 ccggcgattt caccacaccg ctgacgctgt ttgcgctgga tttgaacgtg atggaactga
    12661 ccgtcatgcg ccgccagccg cagcagttcg attcagacgg catcgaagtg cggcagtttt
    12721 gggtgatgtc gtccgacggc gaacgcatcc cttatttcca cgtcggcaaa aacgccgcgc
    12781 ccgacacgcc gacgctggtt tatgcctacg gcggtttcgg cgtacccgag ctgccgcatt
    12841 atctgggcag catcggcaaa tactggctgg aagagggcaa cgccttcgtg ttggcgaaca
    12901 tacgcggcgg cggcgagttc ggcccgcgct ggcatcaggc ggcgcaggga atcagcaaac
    12961 acaaaagcgt cgatgatttg cttgccgtcg tgcgcgattt gtccgagcgc ggcatcagtt
    13021 cgccccaaca catcggtttg cagggcggca gcaacggcgg cctgattacc gccgccgcct
    13081 tcgtgcgcga accgcaaagc ataggcgcac tggtgtgcga agtgccgctg accgacatga
    13141 tccgttatcc gctgctctcc gccggttcaa gctggacaga cgaatacggc aatccgcaaa
    13201 aatacgaagt ctgcaaacgc cggttgggcg aattgtcgcc gtatcacaat ctttcagacg
    13261 gcatcgatta tccgcccgcg ctcatcacca ccagcctcag cgacgaccgc gtccatcccg
    13321 cccacgcgct caagttttac gccaaactgc gcgaaacctc gccgcaatct tggctctact
    13381 cgcctgacgg cggcggccat accggcaacg gcacgcagcg cgaagccgcc gacgaactcg
    13441 cctgcgtgtt gctgtttttg aaagagtttt tgggctaagg gcggggagcg gcactgccgc
    13501 cgcgaatgaa aaaaggtcgt ctgaaactgc tttttcagac gacctttttt aatggttgtt
    13561 tcaaatcaaa atatctatgc cgccggcccc atcagcactt cttcacatcc gaaggcaaaa
    13621 atccgtaatg ccgtctgaac gcttcgttga accgtcccgc gtggcggtag ccgcaaaagt
    13681 gcatggcggc ttggacggtg ctgccggatt cgatgagggc gagcgcgtgt tccagccgca
    13741 ggcggcgcag gcatccggcg acggtttcgc cggtttgcgc tttgaaatag cgtttcaggt
    13801 agcattcgtt cagtccgacg cggcgggcga tttcggcgat ggtcagcgga cgggcgaatt
    13861 cgtgttgcag gatgtcggcg gcttcgtcta tgcgccgacg gcggtaaccg ttgtcgtggc
    13921 ggcggaaggt gaagcgcaat aatcgggcgg agagttccag cgcggcggct tcgtcggcaa
    13981 gcaggccgaa gccgtccgat tcgaacgggc gttgcagcag tgggcaggcc gccgccgtca
    14041 gtgccgccgc gttttgcgcc agccgttgca gggcgaatcg gcctattgtt tgcggcgaaa
    14101 acaggcgttc gtccagcaag ccttcgtcgt gccagcggcg cagtttttcc agcgaaaaat
    14161 ccaaatgcag cgcgcacatg ccgctgttgt cgggcagcag ggtttcggat acgtccgcca
    14221 actcgccgcg taccagccag atttcgccgg cagacgggcg gtattccctg ccgcccattt
    14281 gtaaccggtt ctgccccgac accatgacga acaaggcgca gttgtggctg aaattgtgga
    14341 tttcggtggg aaacgcgccc gttccgccgc cgcgcatccg cgacaaggtg atgcccgaat
    14401 cgaagcggtt gatgcacatt tccagatgca aaccgggctg ttttgcctgc gcaatgagcg
    14461 cgctgtcgga acagccgtcc aacgcccagc cggatttatc ggagcggaca taggtttggt
    14521 actggcggta gatggcggcg gtgttcatga ttggatagga acgagttgtc taacaaatga
    14581 attaaatagg aattattacc aataatcaag cgcagggatt ggttgaaacg gaaaaggtcg
    14641 tctgaaaggg tgtttcagac gaccttttcc gtatcgggaa tttgttttgc cgtatcggga
    14701 attttgcgtt ttgcggcgtg gtttctgcag gttgtttgct taataataaa cattcttatt
    14761 cgtatgcaaa ggaaccgcac accgtgaaac cgcgttttta ttgggcagcc tgcgccgtcc
    14821 tgctgaccgc ctgttcgccc gaacctgccg ccgaaaaaac tgtatccgcc gcatccgcat
    14881 ctgccgccac actgaccgtg ccgaccgcgc ggggcgatgc cgttgtgccg aagaatcccg
    14941 aacgcgtcgc cgtgtacgac tgggcggcgt tggatacgct gaccgaattg ggcgtgaatg
    15001 tgggcgcaac caccgcgccg gtgcgcgtgg attatttgca gcctgcattt gacaaggcgg
    15061 caacggtggg gacgctgttc gagcccgatt acgaagccct gcaccgctac aatcctcagc
    15121 ttgtcattac cggcgggccg ggcgcggaag cgtatgaaca gttggcgaaa aacgcgacca
    15181 ccatagatct gacggtggac aacggcaata tccgcaccag cggcgaaaag cagatggaga
    15241 ccttggcgcg gattttcggc aaggaagcgc gcgcggcgga attgaaggcg cagattgacg
    15301 cgctgttcgc ccaaacgcgc gaagccgcca aaggcaaagg acgcgggctg gtgctgtcgg
    15361 ttacgggcaa caaggtgtcc gccttcggca cgcagtcgcg gttggcaagt tggatacacg
    15421 gcgacatcgg cctaccgcct gtagacgaat ctttacgcaa cgaggggcac gggcagcctg
    15481 tttccttcga atacatcaaa gagaaaaacc ccgattggat tttcatcatc gaccgtaccg
    15541 ccgccatcgg gcaggaaggg ccggcggctg tcgaagtatt ggataacgcg ctggtacgcg
    15601 gcacgaacgc ttggaagcgc aagcaaatca tcgtcatgcc tgccgcgaac tacattgtcg
    15661 cgggcggctc gcggcagttg attcaggcgg cggagcagtt gaaggcggcg tttgaaaagg
    15721 cagaacccgt tgcggcgggg aaagagtagg gagtcgtctg aaaacggagc ttccgaagga
    15781 agcggggggg tttctgcgaa gctaaagtgc ggtttcaacg aattgaaaag cagcctgtat
    15841 gttgaaaata ccgctcaagc aaacctacgg tttgccgccc tctccctagc cctctcccac
    15901 agggagaggg gattgggttg caggctgcct ttaaggttta ggcaaatttt taacttcgtt
    15961 gaagctgcga tttcagaagc tccgttttag cttcgcagaa actctgcttc cttcgaaagc
    16021 tccgttttca gacgaccttt tggagtaccg caggcacacg catcgaacgg ctgaatcaaa
    16081 gttcagaccg atggcagccc gcacccgagt ttatgcggca aacagcgagg ctacggcaac
    16141 ccgtcccctc tccctgtggg agagggttag ggagagggcg gtaagccgca ggcttgcatc
    16201 aaagtcgata acgctttcgt tacaactccg cccactgaac gaagccaaaa cgacaaaccg
    16261 catcgtaaac cacccaaccc ataggagaac cccatgcaaa acgaaaccat caacctgaaa
    16321 cagcaccttg ccgccatcaa agaatactgg cagcccgaaa tcatcaaccg ccacgggttc
    16381 caattccgtt tggtcaaact tttgggcgat tacggctggc atacgcacgg atacagcgac
    16441 aaagtgctgt ttgccgtgga gggcgacatg gcggtggact tcgccgacgg cggcagcatg
    16501 acgatacgcg agggcgagat ggcggtcgtg ccgaagtcgg tgtcgcaccg cccacgttcg
    16561 gaaaacggct gctcggtggt gctgattgag ttgtccgacc cgtccgaggc cgtctgaaaa
    16621 cgaagtttcc gaaggaagct gagtttctgc gaagctaaaa gcagcctgca ccttcaatca
    16681 atatgccgaa aatacaaccc caccgcacac caacacacaa aggaaatccc atgacacgct
    16741 tcaaatattc cctgctgttt gccgccctgt tgcccgtgta cgcgcaggcc gatgtttctg
    16801 tttcagacga ccccaaaccg caggaaagca ctgaattgcc gaccatcacc gttaccgccg
    16861 accgcaccgc gagttccaac gacggctaca ctgtttccgg cacgcacacc ccgctcgggc
    16921 tgcccatgac cctgcgcgaa atcccgcaga gcgtcagcgt catcacatcg caacaaatgc
    16981 gcgaccaaaa catcaaaacg ctcgaccgcg ccctgttgca ggcgaccggc accagccgcc
    17041 agatttacgg ctccgaccgc gcgggctaca actacctgtt cgcgcgcggc agccgcatcg
    17101 ccaactacca aatcaacggc atccccgttg ccgacgcgct ggccgatacg ggcaatgcca
    17161 acaccgccgc ctatgagcgc gtagaagtcg tgcgcggcgt ggcggggctg ctggacggca
    17221 cgggagagcc ttccgccacc gtcaatctgg tgcgcaaacg cccgacccgc aagccattgt
    17281 ttgaagtccg cgccgaagcg ggcaaccgca aacatttcgg gctgggcgcg gacgtatcgg
    17341 gcagcctgaa tgccgaaggc acgctgcgcg gccgcctggt ttccaccttc ggacgcggcg
    17401 actcgtggcg gcagcgcgaa cgcagccgcg atgccgaact ctacggcatt ttggaatacg
    17461 acatcgcacc gcaaacccgc gtccacgcag gcatggacta ccagcaggcg aaagaaaccg
    17521 ccgacgcgcc gctcagctac gccgtgtacg acagccaagg ttatgccacc gccttcggcc
    17581 cgaaagacaa ccccgccaca aattgggcga acagccgcca ccgtgcgctc aacctgttcg
    17641 ccggcatcga acaccgcttc aaccaagact ggaaactcaa agccgaatac gactacaccc
    17701 gcagccgctt ccgccagccc tacggcgtag caggcgtgct ttccatcgac cacaacaccg
    17761 ccgccaccga cctgattccc ggttattggc acgccgaccc gcgcacccac agcgccagcg
    17821 tgtcattgac cggcaaatac cgcctgttcg gccgcgaaca cgatttaatc gcgggtatca
    17881 acggttacaa atacgccagc aacaaatacg gcgaacgcag catcatcccc aacgccattc
    17941 ccaacgccta cgaattttcc cgcacgggcg cctatccgca gccatcatcg tttgcccaaa
    18001 ccatcccgca atacggcatc aggcggcaaa tcggcggcta tctcgccacc cgtttccgcg
    18061 ccgccgacaa cctttcgctg attttgggcg gcagatacag ccgttaccgc accggcagct
    18121 acgacagccg cacacaaggc atgacctatg tgtccgccaa ccgtttcacc ccctacacag
    18181 gcatcgtgtt cgacctgacc ggcaacctgt cgctttacgg ctcgtacagc agcctgttcg
    18241 tcccgcaatc gcaaaaagac gaacacggca gctacctgaa acccgtaacc ggcaacaatc
    18301 tggaagccgg catcaaaggc gaatggcttg aaggccgtct gaacgcatcc gccgccgtgt
    18361 accgcgcccg taaaaataac ctcgccaccg cagcaggacg cgacccgagc ggcaacacct
    18421 actaccgcgc cgccaaccaa gccaaaaccc acggctggga aatcgaagtc ggcggccgca
    18481 tcacgcccga atggcagata caggcaggct acagccaaag caaaacccgc gaccaagacg
    18541 gcagccgcct gaaccccgac agcgtacccg aacgcagctt caaactcttc accgcctacc
    18601 actttgcccc cgaagccccc agcggctgga ccatcggcgc aggcgtgcgc tggcagagcg
    18661 aaacccacac cgaccctgcc acgctccgca tccccaaccc cgccaccaaa gcccgcgccg
    18721 ccgacaacag ccgccaaaaa gcctacgccg tcgccgacat catggcgcgt taccgcttca
    18781 atccgcgcgc cgaactgtcg ctgaacgtgg acaacctgtt caacaaacac taccgcaccc
    18841 agcccgaccg ccacagctac ggcgcactgc ggacagtgaa cgcggcgttt acctatcggt
    18901 ttaaataagg tcgtctgaaa acagagtttc tgcgaag
//
LOCUS       DAXIDM010000035        18431 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000035 DAXIDM010000000
VERSION     DAXIDM010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 18431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18431
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.035"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(7..615)
                     /locus_tag="ACFOAE_000978"
     CDS             complement(7..615)
                     /locus_tag="ACFOAE_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003694442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BON domain-containing protein"
                     /protein_id="HFC6884486.1"
                     /translation="MKPKPHTVRTLIAAIFSLALSGCVSAVIGSAAVGAKSAVDRRTT
                     GAQTDDNVMALRIETTARSYLHQNNQTKGYTPQISVVGYNRHLLLLGQVATEGEKQFV
                     GQIARSEQAAEGVYNYITVASLPRTAGDIAGDTWNTSKVRATLLGISPATQARVKIVT
                     YGNVTYVMGILTPEEQAQITQKVSTTVGVQKVITLYQNYVQR"
     gene            complement(679..1272)
                     /locus_tag="ACFOAE_000979"
     CDS             complement(679..1272)
                     /locus_tag="ACFOAE_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008968 - D-sedoheptulose 7-phosphate
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoheptose isomerase"
                     /protein_id="HFC6884487.1"
                     /translation="MTTLQERVAAHFAESIRAKQEAEKVLVEPTVQAAELMLQCLMND
                     GKILACGNGGSAADAQHFAAEMTGRFEKERMELAAVALTTDTSALTAIGNDYGFNHVF
                     SKQVRALGRAGDVLVGISTSGNSANVIEAIKAAHERDMHVIALTGRDGGKIAAMLKDT
                     DVLLNVPYPRTARIQENHILLIHAICDCIDSVLLEGM"
     gene            complement(1277..1624)
                     /locus_tag="ACFOAE_000980"
     CDS             complement(1277..1624)
                     /locus_tag="ACFOAE_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HFC6884488.1"
                     /translation="MRLNHKQGEAGEDAALAFLQSQGCTLLARNWHCAYGEIDLIVKN
                     GGMILFVEVKYRKNRQFGGVAYSISPSKLLKLQRSVEYYLQQNRLTNVPCRLDAVLIE
                     GNRPPEWIQNITG"
     gene            1678..2553
                     /gene="rsmI"
                     /locus_tag="ACFOAE_000981"
     CDS             1678..2553
                     /gene="rsmI"
                     /locus_tag="ACFOAE_000981"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFC6884489.1"
                     /translation="MFQKHLQKASDSVVGGTLYVVATPIGNLADITLRALAVLQKADI
                     ICAEDTRVTAQLLSAYGIQGKLVSVREHNERQMADKIVGYLSDGMVVAQVSDAGTPAV
                     CDPGAKLAGRVREAGFKVVPVVGASAVMAALSVAGVEGSDFYFNGFVPPKSGERRKLF
                     AKWVRAAFPIVMFETPHRIGATLADMAELFSERRLMLAREITKTFETFLSGTVGEIQT
                     ALSADGNQSRGEMVLVLYPAQDEKHEGLSESAQNIMKILTAELPTKQAAELAAKITGE
                     GKKALYNLALSWKNK"
     gene            complement(2588..2992)
                     /locus_tag="ACFOAE_000982"
     CDS             complement(2588..2992)
                     /locus_tag="ACFOAE_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="HFC6884490.1"
                     /translation="MGSLFGLHKSFGFLTLTVITLRIVWAVANRAKRPQSDSKAAAAG
                     HGILYLLMLAVPVIGMIRQYGSGRGPLKVFGVEVMQGSPEKIEWMANLGNTFHGNLGW
                     LLFAAVVGHVAMVVVHRVQGKDVLYRMTGRVR"
     gene            complement(3057..3221)
                     /locus_tag="ACFOAE_000983"
     CDS             complement(3057..3221)
                     /locus_tag="ACFOAE_000983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884491.1"
                     /translation="MNTNQPAVYDPLTRTLHWLTVAGFIGIPTTIVLWTIYSGLTKIR
                     TRRRSRRQYK"
     gene            3498..4652
                     /gene="obgE"
                     /locus_tag="ACFOAE_000984"
     CDS             3498..4652
                     /gene="obgE"
                     /locus_tag="ACFOAE_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFC6884492.1"
                     /translation="MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGS
                     VWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTD
                     EIVADLTYHGQRVCLAKGGKGGLGNIHFKSSVNRAPKQSTPGEEGEARSLQLELKVLA
                     DVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLI
                     EGAAEGAGLGHRFLKHLSRTGLLLHVVDLAPFDETVNPAEEALAIINELRKYDEELYG
                     KPRWLVLNKLDMLDEEEAQTRTAAFLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQ
                     GTQELVHQINQYLTEKKRIEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE"
     gene            4735..5784
                     /locus_tag="ACFOAE_000985"
     CDS             4735..5784
                     /locus_tag="ACFOAE_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC6884493.1"
                     /translation="MSSNQYIQSLELTNFTVLPNDTFEFSENLNVIVAENGCGKTHLL
                     KILYSLLEVTSNTKNRLLKTELQKSFADKLLNVFRPDSLGRLSKRLQGRGRTEIVLKL
                     QNGTTHSSLNFSSNSSSQVNVQSIGLKENEYTPTPIFLPSRELITLCPWFTSLYQNQS
                     IPFEETWFDTCMQLNHPLAKGPRETKIRELLEPIENAMGGKVSEEQGRFYLSLTNTGG
                     KIEAPLVAEGLRKFVMIARLIATGALLDKGYLFWDEPEANLNPKLIKVAARIIWSLSQ
                     QGIQVFIATHSLFLLRELELLKLENNTDLPVRFFSLIASDDGTKVEQGNSINDLNTLI
                     LLDENIMQADRYLNI"
     gene            6472..7893
                     /gene="cysS"
                     /locus_tag="ACFOAE_000986"
     CDS             6472..7893
                     /gene="cysS"
                     /locus_tag="ACFOAE_000986"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFC6884494.1"
                     /translation="MTTIYNTLTRQKEPFSPIDPENVRMYVCGMTVYDYCHLGHARVM
                     VVFDMIARWLRECGYPLTYVRNITDIDDKIIARAAENGETIGKLTARFIQAMHEDADA
                     LGVLRPDIEPKATENIPQMIAMIETLIQNGKAYPAANGDVYYAVREFAAYGQLSGKSL
                     DDLRAGERVEVDGFKRDPLDFVLWKAAKAGEPAWESPWGNGRPGWHIECSAMSENLFG
                     DTFDIHGGGADLQFPHHENEIAQSVGATGHTCGHHHAQTHHGQSIASHVKYWLHNGFI
                     RVDGEKMSKSLGNFFTIREVLKQYDPEVVRFFILRAHYRSPLNYSDAHLDDAKGALTR
                     LYTTLKNTPPADPMPSEAGDDYTRRFYVAMNDDFDTVKAVAVLFELAGEVNKTNDAQL
                     AGRLKALGGIIGLLQRDPTEFLQGSAASDGLSNEEIEDLIARRKQARADKNWAESDRI
                     RDLLNEHKIILEDNAGGTTWRRG"
     gene            8064..8843
                     /locus_tag="ACFOAE_000987"
     CDS             8064..8843
                     /locus_tag="ACFOAE_000987"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFC6884495.1"
                     /translation="MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADL
                     SADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFDR
                     LSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLK
                     NWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGW
                     RIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVMEYDYAAE"
     gene            8830..9174
                     /locus_tag="ACFOAE_000988"
     CDS             8830..9174
                     /locus_tag="ACFOAE_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884496.1"
                     /translation="MLPNKVLGKYDWNVDGKTGIGAAWVVAAFILPILVWAIFMLSRM
                     QGWLAPTKANPTWALVWLLICMPCLLIASKCLGWKGWRRVVNIFACLTVCAILSVPAS
                     LLIAFTLRDLLK"
     gene            9185..9715
                     /locus_tag="ACFOAE_000989"
     CDS             9185..9715
                     /locus_tag="ACFOAE_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFC6884497.1"
                     /translation="MQGFELEDLTLWLIRDAGEDQMWIDRWAISYPVVQMSEASAGQS
                     IGEWQAGLRTAFERIRGKYVAVVAHGAGAAAFLAWLYQADILTRKKIANIILVPQRPD
                     IFPDDAEHTFQRVRCPCRAALVVPEHGGVPHGWAQKQADLWNARLLVSPHSGSLNGML
                     GGWQWGMKLMQEMLLA"
     gene            complement(9808..10923)
                     /gene="asd"
                     /locus_tag="ACFOAE_000990"
     CDS             complement(9808..10923)
                     /gene="asd"
                     /locus_tag="ACFOAE_000990"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA];
                     GO_process: GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFC6884498.1"
                     /translation="MKVGFVGWRGMVGSVLMQRMQEENDFAHIPEAFFFTTSNVGGAA
                     PDFGQAAKTLLDANDVAELAKMDIIVTCQGGDYTKSVFQALRDSGWNGYWIDAASSLR
                     MKDDAIIVLDPVNRNVIDNGLKNGVKNYIGGNCTVSLMLMALGGLFQNDLVEWATSMT
                     YQAASGAGAKNMRELISGMGAVHAQVADELADPSSAILDIDRKVSDFLRSEDYPKANF
                     GVPLAGSLIPWIDVDLGNGQSKEEWKGGAETNKILGRSDNPTVIDGLCVRIGSMRCHS
                     QALTLKLKKDLPISEIEAILAGANDWVKVIPNEKEASIRELTPAKVTGTLSVPVGRIR
                     KLGMGGEYISAFTVGDQLLWGAAEPLRRVLRIVLGSL"
     gene            11099..11680
                     /locus_tag="ACFOAE_000991"
     CDS             11099..11680
                     /locus_tag="ACFOAE_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFC6884499.1"
                     /translation="MEEKNDYTDAASDNRNGQEIEVGIAGAGDRILAALLNQLFTFLV
                     LLVPFAGLIAFAIKNEGRIGGSEEIFGLLLGMTSFWVGLAGILVYTVVQIYYMSRDGQ
                     SLGKKIMRIRVLKTDGRNPGFVGTVLVREIAWSVLVAIIAAVIGLIAGDNGENAINLL
                     AFLANFVLLFMVKRDRRTLYDILADTVVVKLPK"
     gene            complement(11742..12596)
                     /gene="folD"
                     /locus_tag="ACFOAE_000992"
     CDS             complement(11742..12596)
                     /gene="folD"
                     /locus_tag="ACFOAE_000992"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HFC6884500.1"
                     /translation="MSAQLINGKEVSQKRLQAVAEAVAQRQQDNLHTPCLAVVLVGGD
                     PASAVYVRNKKTACQKCGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLP
                     KHLDSQAVLERISPDKDVDGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGK
                     KAVVVGASNIVGRPQALELLLARATVTVCHSATENLADEVAGADILVVGVGIPNFVKG
                     EWIKPGAVVIDVGINRLDDGSLCGDVEFETAKERAAMITPVPGGVGPMTIATLMENTL
                     HAASLHDA"
     gene            12819..12896
                     /locus_tag="ACFOAE_000993"
     tRNA            12819..12896
                     /locus_tag="ACFOAE_000993"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12854..12856,aa:Pro,seq:tgg)
     gene            12921..12997
                     /locus_tag="ACFOAE_000994"
     tRNA            12921..12997
                     /locus_tag="ACFOAE_000994"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12955..12957,aa:Arg,seq:tct)
     gene            13025..13100
                     /locus_tag="ACFOAE_000995"
     tRNA            13025..13100
                     /locus_tag="ACFOAE_000995"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13058..13060,aa:His,seq:gtg)
     gene            13236..13742
                     /gene="rfaE2"
                     /locus_tag="ACFOAE_000996"
     CDS             13236..13742
                     /gene="rfaE2"
                     /locus_tag="ACFOAE_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase"
                     /protein_id="HFC6884501.1"
                     /translation="MVDAWSVPDFESKICPPEALAARLALLPRPLVFTNGCFDILHRG
                     HVTYLAQARSMGDALVLALNTDASVRRLGKGGDRPVNPLENRAAVAAALESVDLVTWF
                     DGDTPAALIEAVKPEILVKGGDWAADKIVGAAETLARGGQVFSIPFLHQTSTTKTLAK
                     IRAAEGGK"
     gene            13739..15517
                     /locus_tag="ACFOAE_000997"
     CDS             13739..15517
                     /locus_tag="ACFOAE_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/type III pantothenate kinase"
                     /protein_id="HFC6884502.1"
                     /translation="MTVLKPSHWRVLAELADGLPQHVSQLARMADMKPQQLNGFWQQM
                     PAHIRGLLRQHDGYWRLVRPLAVFDAEGLRELGERSGFQTALKHECASSNDEILELAR
                     IAPDKAHKTICVTHLQSKGRGRQGRKWSHRLGECLMFSFGWVFDRPQYELGSLSPVAA
                     VACRRALSRLGLDVQIKWPNDLVVGRDKLGGILIETVRTGGKTVAVVGIGINFVLPKE
                     VENAASVQSLFQTASRRGNADAAVLLETLLVELDAVLLQYARDGFAPFVAEYQAANRD
                     HGKAVLLLRDGETVFEGTVKGVDGQGVLHLETAEGKQTVVSGEISLRSDDRPVSVPKR
                     RDSERFLLLDGGNSRLKWAWVENGTFATVGSAPYRDLSPLGAEWAEKADGNVRIVGCA
                     VCGEFKKAQVQEQLARKIEWLPSSAQALGIRNHYRHPEEHGSDRWFNALGSRRFSRNA
                     CVVVSCGTAVTVDALTDDGHYLGGTIMPGFHLMKESLAVRTANLNRHAGKRYPFPTTT
                     GNAVASGMMDAVCGSVMMMHGRLKEKTGAGKPVDVIITGGGAAKVAEALPPAFLAENT
                     VRVADNLVIHGLLNLIAAEGGESEHT"
     gene            15630..16454
                     /locus_tag="ACFOAE_000998"
     CDS             15630..16454
                     /locus_tag="ACFOAE_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HFC6884503.1"
                     /translation="MKWLFTLLAVLNIAVFGGTVGYKLAVKATGGVPENRAVENTPPA
                     TPAADNAAASVEDTAALLKPGDILTEEQAEQLRLKKEAEQKKLREKKQREEKARREKL
                     AAEKAQAERENGAADALCAAQASLTMDEDDYHRIKGLLGKWSHVASRSVEKRTAKAKP
                     ADKTYRVVLPVSADAENQAAELSAKGFNPIPFDGALSLGVGNSRENAQALQNRLAGAG
                     FGGAYIVEHFAEADRQDDSLSVSRMTVLFTGVNAADADEIRKITSLYGKLNLKSCK"
     gene            complement(17215..18003)
                     /locus_tag="ACFOAE_000999"
     CDS             complement(17215..18003)
                     /locus_tag="ACFOAE_000999"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HFC6884504.1"
                     /translation="MLTLYGETFPSRLLLGTAAYPTPEILKQSVRIAQPAMITVSLRR
                     TGSGGEAHGQGFWSLLQETGVPVLPNTAGCQSVQEAVTTAQMAREVFETDWIKLELIG
                     DDDTLQPDVFQLVEAAEILIKDGFKVLPYCTEDLIACRRLLDVGCQALMPWAAPIGTG
                     LGAVHAYALNVLRERLPDTPLIIDAGLGLPSQAAQVMEWGFDGVLLNTAVSRSGDPVN
                     MARAFALAVESGRLAFEAGPVEARTKAQASTPTVGQPFWHSAEY"
     gene            complement(18217..18411)
                     /gene="thiS"
                     /locus_tag="ACFOAE_001000"
     CDS             complement(18217..18411)
                     /gene="thiS"
                     /locus_tag="ACFOAE_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HFC6884505.1"
                     /translation="MNIILNGEPAELHGTSVADLIAQTAPQKPFAVAVNTVFVPKGAY
                     AETVLNENDKIDIVRPVVGG"
BASE COUNT         4256 a         4678 c         5239 g         4258 t
ORIGIN      
        1 gccgagtcag cgttggacgt agttttggta gagggtgatg actttttgta cgccgacggt
       61 ggtgctgact ttttgggtaa tctgcgcctg ttcttcgggg gtgaggatgc ccataacgta
      121 ggttacgttg ccgtaggtaa cgattttgac gcgcgcctgt gtggcggggc tgatgcccaa
      181 cagcgtggcg cggactttgg atgtgttcca agtgtcgccg gcgatgtcgc cggcagtgcg
      241 cggcagggag gcgacggtaa tgtagttgta cacgccttcg gcggcctgtt cggaacgtgc
      301 aatctgaccg acgaactgtt tttcgccttc ggtggcgact tgtccgagca gcagcaggtg
      361 gcggttgtag ccgacgacgg agatttgggg cgtgtagcct ttggtttggt tgttttggtg
      421 caggtaggaa cgggcggtgg tttcgatacg caacgccata acgttgtcgt cggtttgcgc
      481 gccggtggtt cggcggtcga cggcggattt cgcgccgacg gcggcgcttc cgattactgc
      541 gctgacgcag ccgctaaggg caaggctgaa aatggcggca atcagggtgc ggacggtgtg
      601 cggtttgggt ttcatcgggt gcttcctttc ttgggcgttt cagacggcat tgctttgcgc
      661 catgccgtct gaaaagggtt acattccttc cagcagtacg gagtcgatac agtcgcatat
      721 ggcgtgtatc agcaggatgt ggttttcctg aatgcgggcg gtgcgcggat aggggacgtt
      781 gagcagaacg tcggtgtctt tgagcatggc ggcgattttg ccgccgtcgc ggccggtcag
      841 ggcgatgacg tgcatatcgc gttcgtgtgc cgctttaatg gcttcgatga cgttggcgga
      901 gttgccggaa gtggaaatgc cgaccaagac gtcgcctgca cgtccgaggg cgcgtacctg
      961 tttgctgaag acgtggttga agccgtagtc gttaccgatg gcggtcagcg cggatgtgtc
     1021 ggtggtcagg gcgacggcgg cgagttccat gcgctctttt tcaaagcgtc cggtcatttc
     1081 ggcggcgaag tgctgggcat cggcggccga accgccgttg ccgcacgcca gaatcttgcc
     1141 gtcgttcatc aggcattgca gcatcagctc ggcagcctgt acggtcggct cgaccagtac
     1201 tttttcggct tcctgtttgg cacggatgct ttcggcaaaa tgggcggcaa cgcgttcttg
     1261 taatgtcgtc atatcgtcaa cctgtaatat tctgtatcca ctcgggcggg cggtttcctt
     1321 caatcagtac cgcatcgagg cggcacggta cgtttgtcaa cctgttctgt tgcagataat
     1381 actctacact tcgttgcagt ttcaataatt tggatgggga aatgctgtat gcgacaccgc
     1441 cgaattgccg atttttgcgg tattttactt caacaaacag aatcataccg ccgtttttga
     1501 caatcaggtc gatttcgccg taggcgcagt gccagttgcg ggcaagcagt gtgcagcctt
     1561 gggattggag gaaggcaagc gcggcatctt cccctgcctc gccctgtttg tggtttaggc
     1621 gcataatcgg tttaaccttt ataatttata atgtttgttt ttcagacggc attttttatg
     1681 tttcagaaac acttgcagaa agcctccgac agcgtcgtcg gagggacatt atacgtggtt
     1741 gccacgccca tcggcaattt ggcggacatt accctgcgcg ctttggcggt attgcaaaag
     1801 gcggacatca tctgtgccga agacacgcgc gttaccgcgc agcttttgag cgcgtacggc
     1861 attcagggca aacttgtcag tgtgcgcgaa cacaacgaac ggcagatggc ggacaagatt
     1921 gtcggctatc tttcagacgg catggttgtg gcacaggttt ccgatgcggg tacgccggcc
     1981 gtgtgcgacc cgggtgccaa actcgccggc cgcgtgcgtg aggccgggtt taaagtcgtt
     2041 cccgtcgtgg gcgcaagcgc ggtgatggcg gctttgagcg tggccggtgt ggaaggatcc
     2101 gatttttatt tcaacggttt tgtaccgccg aaatcgggcg aacgtaggaa actgtttgcc
     2161 aaatgggtgc gggcggcatt tcctatcgtc atgtttgaaa cgccgcaccg aatcggggcg
     2221 acgcttgccg atatggcgga actgttctcc gaacgccgat taatgctggc gcgcgaaatt
     2281 acgaaaacgt ttgaaacgtt cttaagcggc acggttgggg aaattcagac ggcattgtct
     2341 gccgacggca accaatcgcg cggtgagatg gtgttggtgc tttatccggc gcaggatgaa
     2401 aaacacgaag gcttgtccga gtccgcgcaa aacatcatga aaatcctcac agccgagctg
     2461 ccgaccaaac aggcggcgga gcttgccgcc aaaatcacgg gcgagggaaa aaaagctttg
     2521 tacaatctgg cactgtcttg gaaaaacaaa tgatgccgga cggaccggca ccatagtgcg
     2581 aacggaatca acggacacgc cccgtcatgc ggtacagcac gtctttgcct tgaacacggt
     2641 ggacgacgac catggcgacg tgtccgacga cggcggcaaa cagcagccag cccaaattgc
     2701 cgtggaacgt gttgcccaag tttgccatcc actcgatttt ttccggcgaa ccctgcatca
     2761 cctcaacgcc gaacactttc aacgggccgc ggccgctgcc gtattggcgg atcatgccga
     2821 taacgggaac ggcaagcatg agcagataca gaatgccgtg tcctgccgcc gcagccttgc
     2881 tgtcgctttg cggacgcttg gcgcggttgg caaccgccca cacgatgcgc aatgtaatca
     2941 ccgtcagcgt aaggaaaccg aaagatttgt gcaggccgaa caggctgccc acccattccg
     3001 cctcttcgta tagtggatta acaaaaacca gtacggcgtt gcctcgcctt gccgtactat
     3061 ttgtactgtc tgcggcttcg tcgccttgtc ctgatttttg ttaatccact ataaatcgtc
     3121 cacaggacaa tggtggtcgg aatgccgatg aaaccggcaa cggtcagcca gtgcagcgta
     3181 cgtgtcaacg ggtcgtaaac ggcaggttgg tttgtgttca taaaaaactt attatatgta
     3241 acggtttgaa cggacattcc gtcgggtcgg aatgtcaaaa aggcgcgatt gtaccaaaga
     3301 agttggacat aattttgttt gcaggctgaa gatttgctta aaaattcatt aagatgggcg
     3361 gaacaaatag tttgggtacg gcgtgttgaa ataccgctta tcccttataa tagcgtccga
     3421 aattctgttc ggacggcatc aaaacacacg gtaatccgtc tgaaccccca tttgaaacca
     3481 acaaacaaga gcattgaatg aaattcatcg acgaagcaaa aatcgaagtc gccgcaggca
     3541 aaggcggtaa tggcgcaacc agtttccgcc gcgaaaaatt cgtaccgcgc ggcggcccgg
     3601 acggcggcga cggcggcaaa ggcggtagcg tctgggcgga agccgacgaa aacaccaaca
     3661 ccctcgtcga ataccgcttc gttaaacgct accaagccaa aaacggcgaa aaaggccacg
     3721 gttccgaccg ttacggcgca ggtgcggacg acatcgtcct caaaatgccc gtcggcaccc
     3781 tcatccgcga cctcgacacc gacgaaatcg ttgccgacct cacttaccac ggacagcgcg
     3841 tctgcctagc caaaggcggc aaaggcggct tgggcaacat ccacttcaaa tcctccgtca
     3901 accgcgcccc aaaacaatcc acgcccggcg aagaaggcga agcccgttcc ctgcaactcg
     3961 aactcaaagt cctcgccgat gtcggcttat tgggtatgcc caacgccggc aaatccaccc
     4021 tgattaccgc cgtatccgcc gcacgcccca aaatcgccaa ctaccccttc accaccctgc
     4081 atccaaactt aggcgtggta cgcatcgacg aaaaccacag cttcgtgatg gccgacatcc
     4141 ccggcctgat tgaaggcgcg gcagaaggcg cgggtttggg gcatcgtttc ctcaaacact
     4201 tatcgcgcac cggattattg ctgcacgtcg tcgatttggc gcccttcgac gaaaccgtca
     4261 accctgccga agaagcactt gctatcatca acgaattgcg caaatacgat gaagaacttt
     4321 acggcaaacc gcgctggctg gtgctgaata aactcgacat gcttgacgaa gaagaagccc
     4381 aaacgcgcac tgccgccttc ctcgaagccg tcggctggga ctaccccaaa cccgacgacc
     4441 gtttccaatt tgacatggaa accccgcgcc tcttccaaat cagcgcgctg acccaccaag
     4501 gcacgcagga attggtacac caaatcaacc aatacctgac cgagaaaaaa cgtatcgaag
     4561 ctgaaaaagc cgaagcggag aaagcagcgg caaatgttga aattatcgaa cagcagccta
     4621 aaacggatac gggcgtgttt aagccggagt gaaaaaagaa agggtttcag acgatatttg
     4681 ttctacaaaa ggttgtttga aacaatttta aagcaagatt gaaatggatt aaaaatgtca
     4741 tctaaccaat atatccagtc gcttgagttg acaaacttta ccgttcttcc aaacgatact
     4801 tttgaatttt ctgaaaatct caatgttatt gttgccgaaa acggttgtgg caaaacacat
     4861 ttgttaaaaa ttttatacag cctgctagaa gtaacatcta acaccaaaaa cagattactg
     4921 aaaacagaat tgcaaaaaag ttttgccgat aaattactga atgttttccg tcccgattcc
     4981 ttgggcaggt tgagcaaacg tttgcagggg cgcgggcgta cggaaatcgt tttaaaactg
     5041 caaaacggca ctacgcatag tagtctgaat ttttccagta actcatcatc gcaagtcaat
     5101 gttcaaagca tcggattgaa agaaaatgaa tatactccga cacctatctt cttacccagc
     5161 cgcgaattaa ttacactttg cccttggttc acttctttgt atcaaaacca aagcatccct
     5221 ttcgaagaaa cttggtttga tacctgtatg caattaaatc acccgcttgc caaaggcccc
     5281 agagaaacaa aaattcgaga attgctcgaa cctattgaga acgcgatggg cggaaaagta
     5341 tctgaagaac aaggaaggtt ttatctatcg ctgacaaata cgggcggtaa gattgaagca
     5401 cctttggtag cagagggttt gcggaaattt gtcatgattg cccggttaat cgcaacaggg
     5461 gcattgctgg ataaaggcta tctattttgg gatgaaccgg aagctaatct gaatcctaaa
     5521 ttgatcaaag tggctgcccg tattatttgg tctttatctc aacagggtat tcaggttttt
     5581 attgcaacac actctttatt cttattgaga gaattggaac ttttgaagct tgaaaataac
     5641 acggatttac ctgtacgttt tttctcgttg attgcttccg atgatggaac aaaagtggag
     5701 caagggaaca gtattaatga tttgaacaca ttgatattgt tagatgaaaa cattatgcag
     5761 gcagacaggt atctgaatat ttgaggttaa gctatgacta caatcacaga aaagagatta
     5821 acctttgctt ttcctgaaga ttattacgtt accaagtatg acgaatggga acattataaa
     5881 atttttcaga acagttgtaa tttacgtaat aaaattgata caaatgaaaa gggaaagaac
     5941 gggataaatc aaagtgtaga tgacgataat ggcagctcag gtgtagatat aatagccctt
     6001 catgaatcga cactttggct aatcgaaatt aaagattatt accgacttgg gcttgagcca
     6061 aatgcccaat caatagatga aaaactttct gacctaccat atttaatcgc aagaaaaatt
     6121 cgagattcat tggcaggatt ggtttctgct aaatttaaag cagaaaaaca ggaagaaaaa
     6181 gatttttctc gcttggcttt agattgtaac gaaataaaaa tagtccttca tattgaaatg
     6241 cctagtataa gaagtaaact ttatccctcg tcatcagatt tagcaaactt attaaaagat
     6301 aagtttaaat tatcagaatt tacaaaaaat tttgcaaact gttatgcaga accaattttc
     6361 acaaatatca gccatattaa taatccgcaa ctacgtaatg ttccttggtc cgtatctaca
     6421 ggaacagaac agaaattatc atccgagcaa caaagattaa tccataatcc catgaccacc
     6481 atctacaaca ccctaacccg tcaaaaagaa cccttttccc ccatcgaccc tgaaaacgtg
     6541 cgtatgtacg tctgcggtat gaccgtttac gattactgcc atttgggaca cgcccgcgtg
     6601 atggtggtgt tcgacatgat tgcccgttgg ttgcgcgagt gcggctatcc gctcacttat
     6661 gtacgcaaca tcaccgacat cgacgataaa atcattgccc gcgcggctga aaacggcgag
     6721 accatcggca aactgactgc gcgtttcatc caagccatgc acgaagatgc cgatgctttg
     6781 ggcgtgttgc gtccggatat tgagccgaag gcaacggaaa acattccgca aatgattgcc
     6841 atgattgaaa ccctgattca aaacggcaag gcatatcctg ccgcaaatgg cgacgtttac
     6901 tacgccgtgc gcgagtttgc cgcttacgga caattgtcgg gcaaatcgtt ggacgacctg
     6961 cgtgcgggcg aacgcgtgga agtggacggt ttcaaacgcg atccgcttga ttttgtgttg
     7021 tggaaagccg ccaaagcagg cgaaccggcg tgggaaagcc cgtggggcaa cggccgtccg
     7081 ggttggcaca ttgaatgctc tgccatgagt gaaaacctgt tcggcgatac cttcgacatc
     7141 cacggcggcg gcgcggattt gcagtttccg caccacgaaa acgaaattgc ccaaagcgtc
     7201 ggcgcgacgg ggcatacctg cggtcatcat cacgcgcaaa cccaccacgg gcaaagcatc
     7261 gccagccacg tcaaatactg gctgcacaac ggctttatcc gcgtggacgg cgaaaagatg
     7321 tccaaatcgc tgggcaactt cttcaccatc cgcgaagtgt tgaaacaata cgatccggaa
     7381 gtcgtgcgct tcttcatcct gcgcgcccac taccgcagcc cgttgaacta ttccgacgcg
     7441 catttggatg atgcaaaagg cgcgttgacg cgtttgtata cgactttgaa aaatacgccg
     7501 cccgccgatc cgatgccgtc tgaagccggc gatgactaca cgcgccgctt ttatgttgcg
     7561 atgaatgatg attttgatac ggtgaaagcg gtggcggtgt tgttcgaact tgccggcgaa
     7621 gtgaacaaaa ccaatgacgc gcaactggca ggccgtctga aagccttggg cggcatcatc
     7681 ggcctgctgc aacgcgaccc gaccgagttc ctgcaaggca gcgcggcttc agacggcctc
     7741 tccaacgaag aaatcgaaga cttgatcgcc cgccgcaaac aggcgcgcgc cgataaaaac
     7801 tgggcggaat ccgaccgcat ccgcgacctt ctgaacgaac acaaaatcat tttggaagac
     7861 aacgccggcg gcacgacttg gcggcgcggt tgaactgtat cggaaagggc aaaagtaccg
     7921 ccttttgctc tttttccgtt ttcagacggc atttcccgct tgaagccccg ccgttttcag
     7981 caggcagggc cgaatgggaa atgccgggcg gcgcaccggg tgctgctttg tgtatgggaa
     8041 cattgtgaga acttattttt attatgctta aaatcatttc cgccaacgtc aacggcatcc
     8101 gctccgccta caaaaaaggt ttttacgaat atatcgccgc atcgggcgcg gacattgtct
     8161 gcgtgcagga actcaaagcg caggaggctg atttgtctgc cgatatgaaa aatccgcacg
     8221 ggatgcacgg ccattggcat tgcgccgaga agcgcggtta cagcggcgtg gcggtgtaca
     8281 gcaaacgcaa acccgacaat gtgcaaatcg gtatgggcat tgaagaattc gacagggaag
     8341 ggcggtttgt gcgttgcgat ttcgacaggt tgagcgttat ttcgctttac ttgcccagcg
     8401 gcagcagcgc ggaagaacgc cagcaggtga aataccgttt ccttgatgcg ttttacccta
     8461 tgctcgaagc gatgaaaaac gaaggacgcg acattgtcgt ttgcggcgac tggaacatcg
     8521 cccaccaaaa catcgacctg aaaaactgga aaggcaatca gaaaaattcg ggcttcctac
     8581 cggaagaacg cgagtggata ggcaaggtta tccacaagct cggttggacg gatatgtggc
     8641 gcacgcttta tcccgatgtg ccgggctaca cgtggtggag caaccgcggg caggcgtatg
     8701 cgaaagatgt cgggtggcgc atcgattatc agatggttac gcccgaactt gccgccaaag
     8761 ccgtgtccgc acacgtttat aaagatgaaa aattttccga ccatgcgccg ctggtcatgg
     8821 agtatgacta tgctgccgaa taaagttttg ggtaaatatg attggaatgt ggacggaaaa
     8881 acaggaatag gcgcagcatg ggttgtcgct gcgtttatcc tgcccatatt ggtgtgggcg
     8941 atatttatgt tgtcgcggat gcaaggctgg cttgcgccga ccaaggcaaa cccgacatgg
     9001 gcgttggtgt ggctgctgat ctgcatgccc tgcctgctga ttgcgtccaa atgtttgggt
     9061 tggaaaggct ggcggcgggt ggtgaatatt tttgcctgcc tgaccgtctg cgccatattg
     9121 agcgtacccg cttcgctgct catcgccttt accctccggg acctgctgaa ataggcgggg
     9181 cggtatgcag ggttttgaac tcgaagattt gacgctttgg ctgatacgcg atgccggaga
     9241 ggatcagatg tggatagacc gttgggcgat cagttatccc gtcgtgcaga tgtccgaagc
     9301 gtcggccggt caaagcatag gggaatggca ggcagggctt cggacggcat ttgaacgcat
     9361 acgtggcaaa tacgtcgccg ttgtcgcaca cggtgcgggc gcggccgcat ttttggcgtg
     9421 gctgtatcag gcagacatcc tgacacggaa gaaaattgcc aacatcatcc ttgtaccgca
     9481 gcgtcccgat atttttcccg acgatgcgga acacactttc caacgcgtcc gctgtccctg
     9541 ccgtgccgca ttggttgtac ccgaacacgg cggcgtgccg cacggttggg cgcaaaaaca
     9601 ggcggatttg tggaacgccc gcctgttggt ttccccgcat tcgggcagtt tgaacggcat
     9661 gctcggcggc tggcagtggg gtatgaagct gatgcaggaa atgttgctgg cgtgaacgct
     9721 tgccttatcg gaatttcggt taactggggt tgcaaggaaa atgccgtctg aaacaggctt
     9781 cagacggcat ttccattcaa acagggctta caggctgccc aacacgatac gcaatacgcg
     9841 gcgcagcggc tcggccgcgc cccacaagag ctggtcgccg acggtgaacg cgctgatgta
     9901 ttcgccgccc atacccagtt tgcggatgcg tccgacgggg acggacagcg tgccggtaac
     9961 tttggcgggg gtcagctcgc ggatgctggc ttctttttcg ttggggatga ctttcaccca
    10021 gtcgttcgcg cctgccaaaa tcgcttcgat ttcggaaatg ggcaggtctt ttttcaactt
    10081 cagggtaagg gcttggctgt ggcagcgcat agagccgatg cggacgcaca ggccgtcaat
    10141 cacggttgga ttgtcgctgc ggccgaggat tttgttggtt tccgcgccgc ctttccattc
    10201 ttctttggac tggccgttgc ccaaatccac gtcaatccac ggaatcaggc tgccggcgag
    10261 cggtacgccg aagttggctt tcggatagtc ttcgctgcgc aggaaatcag atactttgcg
    10321 gtcgatgtcg agaatcgcgc tggaaggatc ggcaagctcg tccgccactt gggcgtgaac
    10381 cgcgcccata ccgctgatga gttcgcgcat atttttcgca cctgcgccgg aagcggcttg
    10441 gtaggtcatg ctggttgccc attcaaccaa atcgttttgg aacaggccgc ccaaagccat
    10501 cagcatcagg gagacggtgc agttgccgcc gatgtagttt ttcacgccgt ttttgaggcc
    10561 gttgtcgatg acattgcggt tgacggggtc gaggacgata atcgcatcgt ctttcatacg
    10621 cagtgaggac gccgcgtcaa tccagtagcc gttccagccg ctgtcgcgca gggcttggaa
    10681 cacggatttg gtgtaatcgc cgccttggca ggtaacgatg atgtccattt ttgccaattc
    10741 ggcaacatcg ttggcatcca acaatgtttt ggctgcctga ccgaaatcag gggctgcgcc
    10801 gccgacgttg gaagtggtaa agaaaaacgc ttcgggaata tgggcgaagt cgttttcttc
    10861 ttgcatacgc tgcatcaaaa cagagccgac catgccgcgc cagccgacga aacctacttt
    10921 cattgtgttg ctccttgagg aaaaatcgtt aacaaaatta tgtatggcgt aaaggaagcg
    10981 ttttaacgcc gtattgggaa aatgtaaagt tctttatcgg gatttcttta agtattggcg
    11041 ttttcggtgt cgtggcggta gaatcggggt cagttaagaa caattatcag gaacggatat
    11101 ggaagaaaaa aacgactaca ccgacgcggc atccgacaac cgcaacgggc aggaaattga
    11161 agtcggaatt gccggcgcag gcgaccggat acttgccgcg ctgctgaacc aattgtttac
    11221 ctttttggtt ttgttggtgc cgtttgccgg actgattgct ttcgccatca agaatgaagg
    11281 caggattggc ggcagtgagg aaatattcgg gctgcttttg ggcatgactt ccttttgggt
    11341 aggactggcg ggcattttgg tttataccgt cgttcaaatc tactatatga gtcgggacgg
    11401 gcagtcattg ggtaagaaaa tcatgagaat ccgcgtgttg aaaaccgacg gccgcaatcc
    11461 cggttttgtc ggcacggttt tggtacgcga aatcgcatgg tcggttttgg ttgccattat
    11521 tgccgccgtt atcggtctta tagcaggtga caacggagaa aacgccatca acctgctggc
    11581 attccttgcc aactttgtcc tgctctttat ggtcaaacgc gaccgccgca cgctttacga
    11641 catactggcg gatacggttg tcgtcaagct gcccaaataa acggacacgg caaaatgccg
    11701 tctgaaagcc tttcagacgg catttttatc ttcagaaccg ctcaagcatc gtgcagtgaa
    11761 gccgcgtgca gggtgttttc catcaatgtg gcaatcgtca tcggacccac gccgccggga
    11821 acgggcgtaa tcatcgccgc ccgttctttt gccgtttcaa attccacgtc gccgcacagg
    11881 ctgccgtcgt ccaaacggtt gatgcccaca tcgataacga ccgcgccggg tttgatccat
    11941 tcgcctttga caaagttcgg aatgcccacg ccgaccacca aaatatcggc tccggcaacc
    12001 tcgtctgcca gattttcggt tgcgctgtgg cagaccgtta ccgttgcgcg cgccagcagc
    12061 aattccaacg cctgcgggcg gccgacgata ttcgacgcgc cgaccacgac cgcttttttc
    12121 cccttcggat caatgccgta agcttccaaa agcgtcatca cgcccttggg cgtacacggg
    12181 cgcatcagcg gcattttgac cgccagcctg ccgacattgt aaggatggaa gccgtccacg
    12241 tccttatccg gcgaaatacg ttccaaaacc gcctggctgt cgaggtgctt cggcagcggt
    12301 agctgaacca gaataccgtc cacttcggaa tcggcattca ggcggtcgac cagtgccagc
    12361 agttcttcct gcgatgttga ttcgggcagc tcgtaagaca gtgatttgat gccgcatttt
    12421 tggcaggcag ttttcttgtt gcggacataa accgcgctgg cagggtcgcc accgaccaaa
    12481 accacggcca ggcaaggcgt gtgcagattg tcctgttggc gttgcgccac cgcttcggca
    12541 accgcctgca ggcgtttttg cgaaacttct ttaccattga tcagttgtgc cgacatatcc
    12601 gtccttttgt taaacaggta gaaaatgctg aaaattatcg cattttccgt ttgtttttac
    12661 agcaggatgc cgaaaataaa tttgccctga aataaaatac ggctgtttgg acggattaaa
    12721 tattttttca aatcaaaaaa ctatattttt catcttggtg tcttgaaaat aaatattgac
    12781 gcatctttcc ctgagttgta tagttcgctt cttcaagtcg gggcgtagcg cagcccggtt
    12841 agcgcatctg ctttgggagc agagggtcgt gagttcgaat cccaccgccc cgaccaatca
    12901 atcagcacga atcggcatga gcgcccgtag ctcaaccgga tagagcaccg accttctaag
    12961 tcgggggtta caggttcgat tcctgtcggg cgtgccaaga atttgattga aaaccgtttt
    13021 tatggtggct gtagctcagt tggtagagcc ccggattgtg attccggttg tcgtgggttc
    13081 gagccccatc agccacccca gataaaggcc cgtacttttc ggtacgggtc tttttccgtt
    13141 tgcgcgtact gtccgcgccg ccggctttgc ctttcgcata tgcttctgta tcatgtgggt
    13201 ttttctgtct tttatggttt ttgtcggagg ctttgatggt tgacgcttgg tctgtccctg
    13261 attttgaatc gaaaatctgt ccgcccgagg cgttggcggc gcgtttggcg ttgttgccgc
    13321 gcccgctggt gtttaccaac ggctgtttcg acatcctcca cagggggcac gttacttatc
    13381 tggcgcaggc gcgttcgatg ggggacgcgt tggtgctggc gttgaatacc gatgcttcgg
    13441 tgcggcgtct gggcaagggc ggtgaccgcc cggttaatcc tttggagaac cgtgccgccg
    13501 ttgccgccgc tttggaaagt gtggatttgg taacgtggtt tgacggggat acgccggcgg
    13561 cgttgattga ggcggtcaaa cctgagattt tggtcaaggg cggcgattgg gctgcggata
    13621 agattgtcgg tgcggcagaa acgttggcgc gcggcggtca ggtgttttca attccgtttc
    13681 tgcaccagac ttcgacaacg aagactttgg caaaaatccg tgcggcagag ggcggaaaat
    13741 gacggttttg aagccttcgc actggcgggt gttggcggag cttgccgacg gtttgccgca
    13801 acacgtctcg caactggcgc gtatggcgga tatgaagccg cagcagctca acggtttttg
    13861 gcagcagatg ccggcgcaca tacgcgggct gttgcgccaa cacgacggct attggcggct
    13921 ggtgcgccca ttggcggttt tcgatgccga aggtttgcgc gagctggggg aaaggtcggg
    13981 ttttcagacg gcattgaagc acgagtgcgc gtccagcaac gacgagatac tggaattggc
    14041 gcggattgcg ccggacaagg cgcacaaaac catatgtgtg acccacctgc aaagtaaggg
    14101 cagggggcgg caggggcgga agtggtcgca ccgtttgggc gagtgtctga tgttcagttt
    14161 tggctgggtg tttgaccggc cgcagtatga gttgggttcg ctgtcgcctg ttgcggcagt
    14221 ggcgtgtcgg cgcgccttgt cgcgtttagg tttggatgtg cagattaagt ggcccaatga
    14281 tttggttgtc ggacgcgaca aattgggcgg cattctgatt gaaacggtca ggacgggcgg
    14341 caaaacggtt gccgtggtcg gtatcggcat caattttgtc ctgcccaagg aagtagaaaa
    14401 tgccgcttcc gtgcaatcgc tgtttcagac ggcatcgcgg cggggcaatg ccgatgccgc
    14461 cgtgctgctg gaaacgctgt tggtggaact ggacgcggtg ttgttgcaat atgcgcggga
    14521 cggatttgcg ccttttgtgg cggaatatca ggctgccaac cgcgaccacg gcaaggcggt
    14581 attgctgttg cgcgacggcg aaaccgtgtt cgaaggcacg gttaaaggcg tggacggaca
    14641 aggcgttctg cacttggaaa cggcagaggg caaacagacg gtcgtcagcg gcgaaatcag
    14701 cctgcggtcc gacgacaggc cggtttccgt gccgaagcgg cgggattcgg aacgttttct
    14761 gctgttggac ggcggcaaca gccggctcaa gtgggcgtgg gtggaaaacg gcacgttcgc
    14821 aaccgtcggt agcgcgccgt accgcgattt gtcgcctttg ggcgcggagt gggcggaaaa
    14881 ggcggatgga aatgtccgca tcgtcggttg cgctgtgtgc ggagaattca aaaaggcaca
    14941 agtgcaggaa cagctcgccc gaaaaatcga gtggctgccg tcttccgcac aggctttggg
    15001 catacgcaac cactaccgcc accccgaaga acacggttcc gaccgctggt tcaacgcctt
    15061 gggcagccgc cgcttcagcc gcaacgcctg cgtcgtcgtc agttgcggca cggcggtaac
    15121 ggttgacgcg ctcaccgatg acggacatta tctcggggga accatcatgc ccggtttcca
    15181 cctgatgaaa gaatcgctcg ccgtccgaac cgccaacctc aaccggcacg ccggtaagcg
    15241 ttatcctttc ccgaccacaa cgggcaatgc cgtcgccagc ggcatgatgg atgcggtttg
    15301 cggctcggtt atgatgatgc acgggcgttt gaaagaaaaa accggggcgg gcaagcctgt
    15361 cgatgtcatc attaccggcg gcggcgcggc aaaagttgcc gaagccctgc cgcctgcatt
    15421 tttggcggaa aataccgtgc gcgtggcgga caacctcgtc attcacgggc tgctgaacct
    15481 gattgccgcc gaaggcgggg aatcggaaca tacttaaaaa atacaccctt tttcaacacg
    15541 gggcggcatc cgtccgaatc cgtccggatt ctgccgcccg acagactgcc gcccaggcgg
    15601 gcggggtttc aaacattgag gaaattctaa tgaaatggct cttcaccctt ttggcggtac
    15661 tcaatattgc cgtattcggc ggcacggtgg gctataaatt ggccgttaaa gcgacgggcg
    15721 gcgtgccgga aaaccgggcc gtcgaaaaca cgccccccgc aacgcccgcc gccgacaatg
    15781 cggcggcatc cgtggaggat acggcggcac tgctcaaacc gggcgacatc ctgaccgaag
    15841 agcaggccga gcagttgcgc ttgaaaaagg aagcggaaca gaaaaaactg agggagaaaa
    15901 aacagcgtga agaaaaagcc cgccgcgaaa aactcgccgc agaaaaggcg caggcggaac
    15961 gcgaaaacgg cgcggcggat gccttatgcg ccgcgcaggc aagcctcacg atggacgaag
    16021 atgactacca ccgcatcaaa ggacttttgg gcaaatggtc gcacgttgcc agcaggagcg
    16081 tcgaaaaacg caccgccaaa gccaaacctg ccgacaaaac ctaccgcgtc gtcctgcccg
    16141 tttccgccga tgccgaaaat caggcggcgg agctgtctgc caaaggtttc aaccccatac
    16201 cgtttgacgg cgcattgagt ttgggtgtcg gcaacagccg ggaaaacgcc caagccctgc
    16261 aaaaccggct tgccggcgcc ggattcggcg gggcgtatat tgtcgaacac tttgccgaag
    16321 ccgacaggca ggacgattct ttgagcgtgt cgcgtatgac ggttttgttt accggcgtga
    16381 atgccgccga tgcggacgaa attcgtaaaa tcacgtccct atacggcaaa ctgaacctca
    16441 agtcttgcaa ataggcgcga aagccggacg ataaacgcca aacccaccgc gaaggtgggt
    16501 ttggcgtttc ggttttgagt atctgatata taaaaaggga atgtatgtct cgtatatgcc
    16561 gactccaagt gtgaaagtga tgatggggaa atatggtgtt taatggttcg gaacggacgg
    16621 cttccgagtg gttttgatta tacgctaata ataataatta tcaataaaaa tttaaaaata
    16681 aatgcagatt ttttgtaata cgatgaaaaa taaacaaatt aacctgtccg ccgatgtttg
    16741 tgattcgggt cggcaaactt tcattgtgtc ggacaaatcg gggtcggcag tcatagctga
    16801 gggcttcgtg cctgacggaa ataagcctgc cgtgtttgaa catccgtccg atttggcgcg
    16861 gacagggttg ctattcgggg ggggtgagcg tggattcggg gatgcgaaag cggtaaaacc
    16921 gttgcggatg aaggcttacg gatggcttta ggtattttta aatgtattca aacaacaaca
    16981 aaacgcttct tctattgccg tatttagggc ttgtgcggca gcctgcacac cgtggagtcc
    17041 gggtgtttct ttggttgcgg tgtcggggcg ggcggcaagg ttttctggcc ggtttccctg
    17101 ttcctcacga caaagccgtg atgcccggga atggcggttt gcccgtttca gaccgccgcc
    17161 gttttgggcc gcgatgccgt ctgaaccgtt cagacggcat ttttgccgcc tttttcaata
    17221 ttccgccgaa tgccaaaacg gttgtccgac tgtcggcgtg ctggcttggg ctttggttcg
    17281 cgcctcgacc ggtccggctt caaatgccag ccgtccggat tcgacggcga gtgcgaaggc
    17341 gcgcgccata ttgaccggat cgccgctgcg ggaaacggcg gtgttcaaaa gcacgccgtc
    17401 aaagccccat tccatcactt gtgccgcctg tgagggcaaa cccaagcccg cgtcgataat
    17461 cagcggcgtg tcgggcaggc gttcgcgcag gacgttcaac gcgtaggcgt gaaccgcgcc
    17521 caaacccgtg ccgatcggag ccgcccacgg cattaacgcc tgacagccca catcgagcag
    17581 gcggcggcag gcaatcaggt cttcggtgca ataaggcagc actttgaagc cgtctttaat
    17641 caggatttcc gccgcttcga caagttggaa cacatccggc tgcaaggtgt cgtcgtcgcc
    17701 gatgagttcg agtttaatcc aatcggtttc aaacacttcg cgcgccattt gcgccgtcgt
    17761 taccgcttcc tgcacgcttt ggcagcctgc cgtgttcggc aggacgggaa cgccggtttc
    17821 ttgaagcagc gaccaaaacc cctgaccgtg cgcctcgccg ccgcttcccg tgcggcgcag
    17881 cgagacggta atcatcgcgg gttgggcgat acggacggat tgtttgagga tttcaggggt
    17941 cgggtaggca gccgtgccga gcagcagccg cgaggggaaa gtttctccgt atagggtgag
    18001 cataatgggt tcctttgtat agtggattaa caaaaaccag tacggcgttg cctcgcctta
    18061 gctcaaagaa aacgattctc taaggtgctg aagcactaag tgaatcggtt ccgtactatc
    18121 cgtactgtct gcggcttcgt cgccttgtcc tgatttaaag ttaatccacc ataacgttgt
    18181 tttggggaca ggggtcgtct gaaaaggcaa aaccgcctag ccgccgacca ccggccgcac
    18241 gatatcgatt ttgtcgtttt cgtttaaaac cgtttccgca tacgcgcctt tggggacgaa
    18301 aacggtgttg accgccacgg caaagggctt ttgcggcgcg gtttgggcga tgaggtcggc
    18361 aacgcttgtg ccgtgaagtt cggcgggttc gccgtttaag atgatgttca tggtttctcg
    18421 atgtttctgt a
//
LOCUS       DAXIDM010000036        17890 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000036 DAXIDM010000000
VERSION     DAXIDM010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17890
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.036"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(122..1447)
                     /locus_tag="ACFOAE_001001"
     CDS             complement(122..1447)
                     /locus_tag="ACFOAE_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HFC6884506.1"
                     /translation="MKKYLFRAALYGIAAAILAACQSKSIQTFPQPDTSVINGPDRPV
                     GIPDPAGTTVGGGGAVYTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCA
                     QAFQTPVHSFQAKQFFERYFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIY
                     GIPDDFISVPLPAGLRSGKALVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIK
                     GRFEGSRFLPYHTRNQINGGALDGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIR
                     IGYADKNEHPYVSIGKYMADKGYLKLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFF
                     RELTGSGNDGPVGALGTPLMGEYAGAVDRHYITLGAPLFVATAHPVTRKALNRLIMAQ
                     DTGSAIKGAVRVDYFWGYGDEAGELAGKQKTTGYVWQLLPNGMKPEYRP"
     gene            1658..2497
                     /gene="efeU"
                     /locus_tag="ACFOAE_001002"
     CDS             1658..2497
                     /gene="efeU"
                     /locus_tag="ACFOAE_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0033573 - high-affinity iron permease
                     complex [Evidence IEA];
                     GO_function: GO:0005381 - iron ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034755 - iron ion transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter permease EfeU"
                     /protein_id="HFC6884507.1"
                     /translation="MLVAFLIMLREGIEAALIVGIVAGFLKQSGHSKLMPKVWFGVVL
                     ASLMCLGLGYGIHSATGEIPQKQQEFVVGIIGLVAVAMLTYMILWMKKAARSMKRQLQ
                     DSVQAALNRGSGQGWALVGMAFLAVAREGLESVFFLLAVFKQSPTWQMPAGAVAGVLA
                     AAVIGALIYQGGMRLNLAKFFRWTGAFLIIVAAGLLAGSLRALHEAGIWNALQDIVFD
                     SSKYLHEDSPLGVLLGGFFGYTDHPTQGEALVWLLYLIPVITWFLCGSRPSETLTRKE
                     ELK"
     gene            2494..3660
                     /gene="efeO"
                     /locus_tag="ACFOAE_001003"
     CDS             2494..3660
                     /gene="efeO"
                     /locus_tag="ACFOAE_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HFC6884508.1"
                     /translation="MRKFNLTALSVMLALGLTACQPPEAEKAAPAASGETQSANEGGS
                     VSIAVNDNACEPMELTVPSGQVVFNIKNNSGRKLEWEILKGVMVVDERENIAPGLSDK
                     MTVTLLPGEYEMTCGLLTNPRGKLVVTDSGFKDTTNEADLEKLSQPLADYKAYVQGEV
                     KELVAKTKTFTEAVKAGDIEKAKSLFADTRVHYERIEPIAELFSELDPVIDAREDDFK
                     DGAKDAGFTGFHRIEYALWVEKDVSGVKEIAAKLMTDVEALQKEIDALAFPPGKVVGG
                     ASELIEEVAGSKISGEEDRYSHTDLSDFQANVDGSKKIVDLFRPLIEAKNKALLEKTD
                     TNFKQVNEILAKYRTKDGFETYDKLGEADRKALQASINALAEDLAQLRGILGLK"
     gene            3924..5189
                     /gene="efeB"
                     /locus_tag="ACFOAE_001004"
     CDS             3924..5189
                     /gene="efeB"
                     /locus_tag="ACFOAE_001004"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA];
                     GO_process: GO:0033212 - iron import into cell [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake transporter
                     deferrochelatase/peroxidase subunit"
                     /protein_id="HFC6884509.1"
                     /translation="MSKNQPAQPTRRTLFKTAIAAGAVGAIGGYLGGKKQGETAERTA
                     ESQHSPQAYPCYGEHQAGIVTPQQAFSIMCAFDVTAQSAKQLENLFRTLTARIEFLTQ
                     GGEYQDGDDKLPPAGSGILGKAFNPDGLTVTVGVGSSLFDGRFGLKDKKPIHLQEMRD
                     FSNDKLQKSWCDGDLSLQICAFTPETCQAALRDIIKHTVQTAVIRWSIDGWQPKSEPG
                     AMAARNLLGFRDGTGNPKVSDPKTADEVLWTGVAANSLDEPEWAKNGSYQAVRLIRHF
                     VEFWDRTPLQEQTDIFGRRKYSGAPMDGKKEADQPDFAKDPEGDITPKDSHIRLANPR
                     DPEFLKKHRLFRRAYSYSRGLASSGQLDVGLVFVCYQANLADGFIFVQNLLNGEPLEE
                     YISPFGGGYFFVLPGVEKGGFLGQGLLGV"
     gene            complement(5261..5590)
                     /locus_tag="ACFOAE_001005"
     CDS             complement(5261..5590)
                     /locus_tag="ACFOAE_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFC6884510.1"
                     /translation="MSLPPCPQCASEYTYEDGGQYICPECAHEWNETESAADLAAQVL
                     DANGAVLQNGDTVILIKDLKVKGSSMVIKQGTKVKGIRLQEGDHNIGCKIDGSAMNLK
                     SEFVKKA"
     gene            complement(5667..7037)
                     /gene="glmU"
                     /locus_tag="ACFOAE_001006"
     CDS             complement(5667..7037)
                     /gene="glmU"
                     /locus_tag="ACFOAE_001006"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0000902 - cell morphogenesis [Evidence
                     IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFC6884511.1"
                     /translation="MPQNTLNIVILAAGKGTRMYSKMPKVLHEIGGETMLGRVIDTAA
                     ALNPQNICVVVGHGKEQVLDTVKRDVVWVEQTEQLGTGHAVKTALPHLAAEGRTLVLY
                     GDVPLIDVETLETLLEAAGNEVGLLTDVPADPSGLGRIIRDGSGSVTAIVEEKDASAA
                     QKAVKETNTGILVLPNAKLENWLNSLSSNNAQGEYYLTDLIAKAVADGIKVHPVRVRA
                     SHLAAGVNNKRQLAELERIFQTEQAQELLKAGVTLRDPARFDLRGRLKHGQDVVIDVN
                     CIFEGEVEIGDNVEIGANCVIKNAKIGANSKIAPFSHLEDCEVGENNQIGPYARLRPQ
                     AKLANDVHVGNFVEIKNAAIGKGTKANHLTYIGDAEVGSKTNFGAGTIIANYDGVHKH
                     KTVIGDEVRIGSNCVLVSPVKIGNKVTTGAGSTITRNVEDGKLALARSRQTIIDGWVR
                     PEKNKQ"
     gene            complement(7092..7364)
                     /locus_tag="ACFOAE_001007"
     CDS             complement(7092..7364)
                     /locus_tag="ACFOAE_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex protein"
                     /protein_id="HFC6884512.1"
                     /translation="MRKTFLILMTATALLSGCAWETYQDGNGKTAVRQKYPAGTPVYY
                     QDGSYSKNMNYNQYRPERHAVLPNQTGNNADEEHRQHWQKPKFQNR"
     gene            complement(7390..8070)
                     /locus_tag="ACFOAE_001008"
     CDS             complement(7390..8070)
                     /locus_tag="ACFOAE_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HFC6884513.1"
                     /translation="MQENPTVWLFDLDNTLHNADAGIFTLINRAMTRYMAHRLKLSES
                     AASDLRQEYWHRYGATLAGLQIHHPEIDIADFLRESHPIDAILTRLHGMPETQNTLSR
                     LKGRKAVFSNGPSFYVRAVVGALGLENRFDALFGTDDFGLLYKPNPQAYLNVCRLLDV
                     PPECCIMVDDSADNLHQAKALGMKTVWFGAKSHALPFIDACARDMAQLARYAETLSEH
                     RQNHYNTP"
     gene            8129..9130
                     /locus_tag="ACFOAE_001009"
     CDS             8129..9130
                     /locus_tag="ACFOAE_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6884514.1"
                     /translation="MKRKIWLLPLLAVSAYLQAQTEVRLAVHKSFSLPKGLIARFERA
                     NDAKVSIIQAGGANEMLNKLILSRANPIADAVYGLDNANIGKAREMGILAAAQPESAP
                     VAVGLPSALAVDYGYVSINYDKKWFEGKKLPLPQTLQDLTRPEYKNLLVVPSPATSSP
                     GLGFLMANISGLGEEGAFKWWAQMRQNGVKVAKGWSEAYYTDFSHNGGAYPLVVGYAA
                     SPAAEVYFSKGKYSEPPTGNLFLKGGVFRQVEGAAVLKGAKQPELAAKLVQWLQSREV
                     QQAVPSEMWVYPAVKNTRLPDVFRFAQAPTHTTAPAQRDIDANQRGWVSRWIRTVLK"
     gene            9224..10072
                     /locus_tag="ACFOAE_001010"
     CDS             9224..10072
                     /locus_tag="ACFOAE_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFC6884515.1"
                     /translation="MDFKQFDFLHLISVSGWEHLAEKAWAFGLNLAAALLIFLVGKWA
                     AKRIVAVMRAAMTRAQVDATLISFLCNVANIGLLILVIIAALGRLGVSTTSVTALIGG
                     AGLAVALSLKDQLSNFAAGALIILFRPFKVGDFIRVGGFEGYVREIKMVQTSLRTTDN
                     EEVVLPNSVVMGNSIVNRSTLPLCRAQVIVGVDYNCDLKVAKEAVLKAAVEHPLSVQN
                     EERQAAAYITALGDNAIEITLWAWANEADRWTLQCDLNEQVVENLRKVNINIPFPQRD
                     IHIINS"
     gene            10098..10583
                     /locus_tag="ACFOAE_001011"
     CDS             10098..10583
                     /locus_tag="ACFOAE_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family protein"
                     /protein_id="HFC6884516.1"
                     /translation="MDALHTIARNLTKKRQTVSCAESCTGGMLAAAFTSVAGSSQWFD
                     QSFVTYSNKAKEDRLGVLPETLLEHGAVSRQTVYEMARGAKAVAQADYAVGISGIAGP
                     GGGSESKPVGTVWFGFAFPGGSCEAMRRFDGNRESVRAQAVAFALERLAGLIENGGDA
                     V"
     gene            complement(10685..12253)
                     /gene="msrAB"
                     /locus_tag="ACFOAE_001012"
     CDS             complement(10685..12253)
                     /gene="msrAB"
                     /locus_tag="ACFOAE_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional peptide-methionine (S)-S-oxide
                     reductase MsrA/peptide-methionine (R)-S-oxide reductase
                     MsrB"
                     /protein_id="HFC6884517.1"
                     /translation="MKHRTFFSLCAKFGCLLALGACSPKIVDAGAATVPHTLSTLKTA
                     DNRPASVYLKKDKPTLIKFWASWCPLCLSELGQTEKWAQDAKFSSANLITVASPGFLH
                     EKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVYPSWALIGKDGDVQRIVKGSI
                     NEAQALALIRDPNADLGSLKHSFYKPDTQKKDSKIMNTRTIYLAGGCFWGLEAYFQRI
                     DGVVDAVSGYANGNTKNPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYFFRVVDP
                     TSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAE
                     EYHQDYLIKNPNGYCHIDIRKADEPLPGKTKAAPQGKGFDAATYKKPSDAELKRTLTE
                     EQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPID
                     AKSVTEHDDFSYNMRRTEVRSHAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQ
                     MDAAGYGALKSKVK"
     gene            12398..13663
                     /gene="ftsY"
                     /locus_tag="ACFOAE_001013"
     CDS             12398..13663
                     /gene="ftsY"
                     /locus_tag="ACFOAE_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFC6884518.1"
                     /translation="MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVE
                     SLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAEEAAEKAAEQVEAAKEAIAETVG
                     EAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
                     VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPET
                     KEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNN
                     VTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKA
                     MPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRP
                     VPVRYIGVGEGIDDLRPFDARAFVDALLD"
     gene            14476..14760
                     /locus_tag="ACFOAE_001014"
     CDS             14476..14760
                     /locus_tag="ACFOAE_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFC6884519.1"
                     /translation="MQPAVYILASQRNGTLYIGVTSDLVQRIYQHREHLIEGFTSRYN
                     VTMLVWYELHPTMESAITREKQLKKWNRAWKLQLIEENNVSWQDLWFDII"
     gene            15294..17890
                     /gene="pilC"
                     /locus_tag="ACFOAE_001015"
                     /pseudo
     CDS             15294..17890
                     /gene="pilC"
                     /locus_tag="ACFOAE_001015"
                     /inference="COORDINATES: protein motif:HMM:NF040838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PilC family type IV pilus tip adhesin"
BASE COUNT         4168 a         4474 c         5148 g         4100 t
ORIGIN      
        1 aatttgatcc actataattc cgtcaaataa gaaaggaatt ttgtgcctgc ggtatcgcaa
       61 aacttcgcct taatgcgccc gattgcctag ggatgggctt cagacggcat tgttttccgg
      121 tttacgggcg gtattcgggc ttcataccgt tgggcagaag ctgccagaca tatcccgtgg
      181 ttttctgttt gccggcaagt tcgccggctt cgtcgccgta accccaaaaa taatccacgc
      241 gcaccgcgcc tttaatcgcg ctgccggtat cctgcgccat aatcaggcgg ttgagggctt
      301 tgcgggtaac cggatgggcg gtggcgacaa ataagggcgc acccaaggta atgtagtgcc
      361 ggtcgactgc gccggcatat tcccccatca gcggcgtgcc cagtgcgccg acagggccgt
      421 cattgccgct tccggtaagc tcgcggaaaa agatatagct ggggttttga cccaaaactt
      481 cggcgaggcg ttgcggattt tgccgcatat aagacttaat gccctgcatg gaggtttgtc
      541 cgagtttgag gtagccctta tccgccatgt attttccgat ggaaacatac ggatgctcgt
      601 ttttgtcggc atagccgatg cggatgtatt tgccggacgg ggttttcaga cggcccgagc
      661 cttggatgtg cataaaaaaa agttcgacag ggtcttcggc gtaaccgagt atcggtgctt
      721 tgccgtcaag cgcgccgccg ttgatttggt tgcgcgtgtg gtaggggagg aagcggcttc
      781 cttcaaacct gcctttgatt gccgttgtgc gcgcagtgat ggggaattgg gagaggtcgg
      841 cggtatgtgt gccgccggta ttgtcgattg tgccgctgtt ttttcctgtc tgcctgatgc
      901 ggacaagggc ttttccgctc cgcaaaccgg caggcagggg gacggagata aaatcgtcgg
      961 gaataccgta aatcgggaag cgggcttgtg ccgtccgcct gtcgtcgccc ttcagcaccg
     1021 gctcgtaata gccggtaacc gtgccagcaa ggcttccgtt gcctgcaacc tgccacggcg
     1081 tgaaatagcg ttcaaaaaac tgttttgcct gaaaggaatg gacgggggtt tgaaaggctt
     1141 gggcacacac atcctgccag ccttggcggt ttttcaaatt ggcgcagccg aggcggaagg
     1201 attgcaggct tttggcgaaa tcctgcgccg cccagtgggg cagggacagg tgcggcacaa
     1261 cggtataaac ggccccgccg ccgccgaccg tcgttccggc ggggtcgggg atgccgaccg
     1321 gccggtccgg gccgttgatg acggatgtgt cgggttgcgg aaaggtttgg atgctcttgc
     1381 tttggcaggc ggcgaggatg gcggcggcga tgccgtacag ggcggcgcgg aataggtatt
     1441 ttttcataat ggacaatgtt gccggcagta ataagaaaga tggtttcggg cggcgttgcg
     1501 gcagccgtgg agaggggatt ttaacacagg gcgcagctgc agcctgcgga actttccgcc
     1561 gcgcggcaat gcagataaaa ataacttgca tttgtattta caaacaatga aaatattccg
     1621 ataatatatt attcatcatc cttgttcgtt cgcgtttatg ctggtcgctt ttttaattat
     1681 gttgcgcgag ggtatcgaag ccgcgctcat cgtcggcatc gttgccggtt ttctgaaaca
     1741 gtccggacat tccaaactga tgcctaaggt ctggttcggg gtcgtccttg cttctttgat
     1801 gtgtttgggg ctggggtacg gcatccattc ggcaacgggc gagattcccc aaaagcagca
     1861 ggagttcgtc gtcggcatta ttggtctggt tgctgtcgcg atgctgactt atatgatttt
     1921 atggatgaaa aaggcggcgc gttcgatgaa gcggcagctt caggactccg tgcaggcggc
     1981 tttgaaccgt ggcagcggtc aaggatgggc cttggtcggt atggcgtttc ttgccgtggc
     2041 gcgcgaaggt ctggagagcg tttttttcct gcttgccgta ttcaaacaga gcccgacgtg
     2101 gcagatgccg gccggtgcgg tagcgggggt tttggctgcc gccgtgattg gcgcgttgat
     2161 ttatcagggt gggatgcgcc tgaatctggc gaagtttttc cgttggacag gggcgtttct
     2221 gattatcgtt gccgctggtc tgcttgccgg ttcactgcgt gcgctgcacg aagcaggcat
     2281 ttggaacgcg cttcaggaca ttgtgttcga ctcatcaaaa tatttgcacg aagacagccc
     2341 gttgggcgtg ctgctcggcg gatttttcgg ctataccgac catccgacgc agggcgaggc
     2401 cttggtttgg ctgctgtacc ttattcccgt cataacttgg tttttgtgcg gcagcaggcc
     2461 gtctgaaact ttaacccgta aagaggagct gaaatgagaa aattcaattt gaccgcattg
     2521 tccgtgatgc ttgccttagg tttgaccgcg tgccagccgc cggaggcgga gaaagctgcg
     2581 ccggccgcgt ccggtgagac ccaatccgcc aacgagggcg gttcggtcag tatcgccgtc
     2641 aacgacaatg cctgcgaacc gatggaactg accgtgccga gcggacaggt tgtgttcaat
     2701 attaaaaaca acagcggccg caagctcgaa tgggaaatcc tgaaaggcgt gatggtggtg
     2761 gacgagcgcg aaaacatcgc ccccggactt tccgataaaa tgaccgtcac cctgttgccg
     2821 ggcgaatacg aaatgacttg cggtcttttg accaatccgc gcggcaagct ggtggtaacc
     2881 gacagcggct ttaaagacac caccaacgaa gcggatttgg aaaaactgtc ccaaccgctc
     2941 gccgactata aagcctacgt tcaaggcgag gttaaagagc tggtggcgaa aaccaaaacc
     3001 tttaccgaag ccgtcaaagc aggcgacatt gaaaaggcga aatccctgtt tgccgacacc
     3061 cgcgtccatt acgaacgcat cgaaccgatt gccgagcttt tcagcgaact cgaccccgtc
     3121 atcgatgcgc gtgaagacga cttcaaagac ggcgcgaaag atgccggatt taccggcttt
     3181 caccgtatcg aatacgccct ttgggtggaa aaagacgtgt ccggcgtgaa ggaaattgca
     3241 gcgaaactga tgaccgatgt cgaagccctg caaaaagaaa tcgacgcatt ggcgtttcct
     3301 ccgggcaagg tggtcggcgg cgcgtccgaa ctgattgaag aagtggcggg cagtaaaatc
     3361 agcggcgaag aagaccggta cagccacacc gatttgagcg acttccaagc caatgtggac
     3421 ggatcgaaaa aaatcgtcga tttgttccgt ccgctgatcg aggccaaaaa caaagccttg
     3481 ttggaaaaaa ccgataccaa cttcaaacag gtcaacgaaa ttctggcgaa ataccggact
     3541 aaagacggtt ttgaaaccta cgacaagctg ggcgaagccg accgcaaagc gttacaggcc
     3601 tctattaacg cgcttgccga agaccttgcc caacttcgcg gcatactcgg cttgaaataa
     3661 gccgcaagcg ttcagacggt atttggcggc agataccgtc tgaagtttta tagtggatta
     3721 acaaaaacca gtacggcatt gcctcgcctt gccttgccgt actatttata ctgtctgcgg
     3781 cttcgtcgcc ttgtcctgat ttttgttaat ccactatatc cgccatatat tgcagggcag
     3841 gatttcaacc tgccgctatc ggttaatgga aaaacggcgt gcagggatac ccatcctgct
     3901 gcacggatat tgaaggaaac accatgagca aaaaccaacc cgcacaaccg accaggcgca
     3961 ctctttttaa aaccgcgatc gcagccggag cagtcggcgc aatcggaggt tatctcggcg
     4021 gcaaaaaaca gggcgaaacc gccgaacgca ccgccgaaag ccaacactcg ccccaagcct
     4081 atccctgcta cggcgaacat caggcaggca tcgttacgcc gcagcaggcg ttttcgatta
     4141 tgtgcgcctt cgacgtaacc gcgcaaagtg ccaagcagct ggaaaacctg ttccgcacgc
     4201 tgaccgcccg catcgagttt ctcacccaag gcggcgaata ccaagacggc gacgacaaac
     4261 ttccgccagc cggcagcggc attttgggca aagccttcaa ccccgacggg ttgaccgtta
     4321 ccgtgggggt gggcagcagc ctgtttgacg gcaggttcgg actcaaagac aaaaaaccga
     4381 ttcatttgca ggaaatgcgc gacttctcca acgataagct gcaaaaaagc tggtgcgacg
     4441 gcgatttgag cctgcaaatc tgtgccttca cccccgaaac ctgccaagcc gccctgcgcg
     4501 acatcatcaa acacaccgtc caaaccgccg ttatccgttg gagtatcgac gggtggcagc
     4561 ccaaatccga acccggcgcg atggcggcgc gcaacctgtt gggcttcagg gacggcacgg
     4621 gcaaccccaa agtttccgat cccaaaactg ccgacgaggt tttgtggacg ggtgtggccg
     4681 ccaacagcct cgacgaaccg gagtgggcga aaaacggcag ctatcaggca gtccgcctta
     4741 tccgccactt tgtcgagttt tgggacagga cgccgcttca agagcaaacc gacattttcg
     4801 ggcggcgcaa atacagcggt gcgccgatgg acggcaaaaa agaagccgac caaccggatt
     4861 ttgccaaaga ccccgagggt gatatcacgc ccaaagacag ccatatacgc ctggcgaatc
     4921 cgcgcgatcc cgaattcctc aaaaaacacc gcctcttccg ccgcgcctac agctattcgc
     4981 gcggactcgc ctcaagcgga cagcttgatg tcgggctggt gttcgtctgc tatcaggcaa
     5041 accttgccga cggattcatc ttcgtgcaaa acctcctcaa cggcgaaccg ctggaagaat
     5101 acatcagccc cttcggcggc ggctatttct tcgtcttgcc cggcgtggaa aaaggcggct
     5161 ttttggggca agggctgctg ggcgtataaa tccgccatat aaaaaacgcc gtccgaacct
     5221 tgccaaacgg gttcggacgg cgtttcttgt ttttgggcgg tcaggctttt ttgacgaatt
     5281 cggattttaa attcatcgcg ctgccgtcga ttttgcagcc gatgttgtga tcgccttctt
     5341 gcaggcgtat gcctttgact tttgtgcctt gtttgatcac catcgagctg ccttttacct
     5401 tgaggtcttt gatgaggatg acggtatcgc cgttttgcag cactgcgccg ttggcatcga
     5461 gcacttgagc cgcaaggtcg gcggcggatt cggtttcatt ccattcgtgg gcgcattcgg
     5521 ggcagatgta ttgtccgccg tcttcataag tgtattcgga ggcgcattgt gggcatgggg
     5581 gtaatgacat ggtttgcagt ccttatctga tatcggagga gtttgatgcc gtctgaaacc
     5641 tgaaaccggc ttcagacggc atagctttat tgtttgtttt tttcaggcct cacccagccg
     5701 tcgatgatgg tttggcggga gcgggcgagg gcgagtttgc cgtcttcgac attgcgggta
     5761 atcgtgctgc ccgcgccggt ggttactttg ttgccgattt tgacggggga gaccaagacg
     5821 cagtttgaac cgatgcgcac ttcgtcgccg atgacggttt tgtgtttgtg cacgccgtcg
     5881 tagttggcaa taatcgtacc tgcgccgaag ttggttttgc tgccgacttc ggcatcgccg
     5941 atgtaggtga ggtggttggc tttggtgcct ttgccgatgg cggcgttttt gatttcgacg
     6001 aagttgccga cgtgtacgtc gttagctagt ttggcttgcg gacgcaaacg ggcgtatggg
     6061 ccgatttggt tgttttcgcc gacttcgcag tcttcaaggt gggagaaggg ggcgattttg
     6121 ctgtttgcgc cgattttggc gtttttgatg acgcagtttg cgccgatttc gacgttgtcg
     6181 ccgatttcga cttcgccttc aaagatacag ttcacatcaa ttacgacatc ctgtccgtgt
     6241 ttcagacggc ctcgtaaatc gaaacgtgcc ggatcgcgca gggttacgcc tgctttgagc
     6301 aattcttgtg cctgttcggt ttggaagatg cgttcgagtt cggcgagctg gcgtttgttg
     6361 ttcacgccgg cggcgaggtg ggaggcgcgc actcggacgg gatgaacttt aataccgtcg
     6421 gcaacggctt tggcgatgag gtcggttaaa taatattcgc cttgggcatt gttgctggaa
     6481 aggctgttca gccagttttc cagtttggcg ttgggcagga cgagaatgcc tgtgttggtt
     6541 tctttcacgg ctttttgggc ggcacttgcg tctttttctt cgacaatggc ggttacgctg
     6601 ccgctgccgt cgcggatgat gcgccccaaa cctgacgggt cggcgggcac gtcggtcaac
     6661 agcccgactt cgttgcctgc ggcttcgagc agggtttcga gggtttcaac gtcaattaaa
     6721 ggaacgtcgc cgtacaacac cagcgtgcgg ccttcggcgg caaggtgggg cagggcggtt
     6781 ttgacggcgt ggccggtgcc gagctgttcg gtttgttcaa cccagacgac atcgcgtttg
     6841 acggtgtcta aaacttgctc tttgccgtgg ccgacgacga cgcagatgtt ttgcggattc
     6901 agcgcggcgg cggtgtcgat aacgcgcccg agcattgttt cgccgccgat ttcgtgcaaa
     6961 accttgggca ttttggaata catgcgcgtg cctttgccgg cggcgaggat gacgatgttt
     7021 aaagtgtttt gcggcatagc gttttcctgt gcaatgccgt ctgaaagggc ttcagacggc
     7081 atagggtggg tttatcggtt ttgaaatttg ggcttttgcc agtgttggcg atgctcttcg
     7141 tcggcgttgt tgccggtttg gttgggtaac acggcatggc gttcggggcg gtattggttg
     7201 tagttcatat ttttcgagta gctgccgtct tggtaataaa cgggcgtgcc ggcaggatat
     7261 ttttgacgga cggcggtttt gccgttgccg tcttgataag tttcccacgc gcagcccgac
     7321 aaaagggcgg tggcagtcat caggataagg aaggttttac gcatggcttt tctttcgtat
     7381 tttcgggggt tagggggtat tgtaatgatt ttggcggtgt tctgacaaag tttctgcata
     7441 ccgagccagt tgcgccatat cgcgtgcgca ggcatcgata aagggcagcg cgtgggattt
     7501 tgcgccgaac cagacggttt tcatgcccaa tgcttttgcc tgatgcaggt tgtccgcgct
     7561 gtcgtccacc ataatgcagc attcgggcgg tacgtccaaa aggcggcaga cattgagata
     7621 cgcttgcgga ttgggtttgt acagcagtcc gaaatcatcc gtgccgaaca gtgcgtcgaa
     7681 acggttttcc aaaccgagtg cgccgacaac ggcgcggacg taaaacgacg ggccgttgga
     7741 aaaaactgcc ttgcgccctt ttaggcggct cagggtgttt tgtgtttcag gcatgccgtg
     7801 cagcctggtc aggattgcat cgatcggatg gctttcgcgc aaaaaatcgg cgatgtcgat
     7861 ttcgggatgg tggatttgca gtccggcaag cgttgcgccg tagcggtgcc aatattcctg
     7921 acgcaggtcg gacgcggcgg attcggagag tttgaggcgg tgtgccatat agcgtgtcat
     7981 agcgcggttg atgagtgtga agatgccggc atcggcattg tgcagcgtgt tgtcgaggtc
     8041 gaacagccac acggtcgggt tttcttgcat gttgaaccgt gaaaatttgt tagaatgtta
     8101 ttttacagcg aatagaggag gactcggaat gaaacggaaa atttggctgc tgccgctgct
     8161 ggcggtttcg gcatacctgc aggcgcagac ggaagtcagg ctggcggtgc ataagtcgtt
     8221 cagcctgccc aaagggttga ttgcgcgctt cgagcgggca aacgatgcga aggtgtcgat
     8281 tattcaggcg ggcggcgcga acgaaatgct caacaaactg attttgagcc gcgccaaccc
     8341 gattgccgac gcggtgtatg gtttggacaa cgccaatatc ggcaaggcgc gggaaatggg
     8401 cattttggcg gcggcgcaac ccgaatccgc ccccgtcgcg gtcgggctgc cttcggcttt
     8461 ggcggtcgat tacggctatg tgtccatcaa ttacgacaaa aaatggtttg aaggcaaaaa
     8521 gctgcccctg ccgcaaaccc tgcaggattt gacccgcccc gaatataaaa acctattggt
     8581 cgtgccgtcc cccgccacgt cgtccccggg gctgggcttc ctgatggcga acatcagcgg
     8641 tctgggcgaa gaaggcgcgt tcaaatggtg ggcacagatg cggcagaacg gcgtgaaggt
     8701 cgccaaaggc tggagcgagg cgtattacac cgacttttcg cacaacggcg gcgcgtatcc
     8761 gctggtggtc ggttatgccg ccagcccggc ggcggaagtg tatttttcca aaggcaagta
     8821 cagcgagccg ccgacgggca acctgttttt aaaaggcggc gtattccgtc aggtcgaagg
     8881 tgcggcggtc ttgaagggcg cgaaacagcc ggaattggcg gcaaaactgg tgcaatggct
     8941 gcaaagtcgg gaagtgcagc aggcggttcc gtccgaaatg tgggtttacc ccgccgtcaa
     9001 aaacacgcgc ctgcccgacg tgttccgctt cgcccaagcc ccgacgcaca ccaccgcccc
     9061 cgcgcagcgc gatattgatg cgaaccagcg cggatgggtt tcccgttgga ttagaacggt
     9121 tttgaaataa aacaaacata ccgccccgca gggcttcata cggcattttt acacctgtgc
     9181 cgattacgcc gcatggggcg gatgttcgat caagaggaaa acaatggact tcaaacaatt
     9241 tgatttttta cacctgatca gtgtttccgg ttgggagcat ctggctgaaa aggcgtgggc
     9301 gttcgggctg aaccttgccg ccgcgctgct tatttttttg gtcggaaaat gggcggcgaa
     9361 acgcattgtc gccgtgatga gggcggcgat gacgcgcgcg caggtcgatg ccacgctgat
     9421 tagttttttg tgtaatgttg ccaatatcgg cttattgatt ttggtgatta ttgccgcatt
     9481 gggcagattg ggcgtttcca caacatccgt aaccgcctta atcggcggcg cgggtttggc
     9541 ggtggcgttg tccttgaaag accagctgtc caattttgcc gccggcgcgc tgattatcct
     9601 gttccgcccg ttcaaagtcg gcgattttat ccgcgtcggc ggttttgaag gatatgtccg
     9661 agagattaaa atggtgcaga cttctttgcg gacgaccgac aacgaagaag tcgtgctgcc
     9721 caacagcgtg gtgatgggca acagcatcgt caaccgttcc acactgccgc tgtgccgcgc
     9781 ccaagtgata gtcggcgtcg attacaactg cgatttgaaa gtggcgaaag aggcggtgtt
     9841 gaaagccgcc gtcgaacacc ccttgagcgt tcaaaacgaa gagcggcagg ccgccgccta
     9901 catcaccgcc ttgggcgaca atgccatcga aatcacatta tgggcttggg caaacgaagc
     9961 agaccgctgg acgctgcaat gcgacttgaa cgaacaagtg gtcgaaaacc tccgcaaagt
    10021 caatatcaac atcccgttcc cgcaacgcga catacacatc atcaattctt aaacgccgtc
    10081 tgaaagggga gtgggaaatg gacgcgctgc acaccatcgc ccgaaacctg acgaaaaaac
    10141 gtcaaaccgt aagctgtgcc gaatcctgta cgggcggaat gcttgccgcc gcattcacaa
    10201 gcgttgcagg cagttcgcaa tggttcgatc aaagttttgt aacatacagc aacaaagcca
    10261 aagaagaccg cttgggcgtg ttgcccgaaa ccctgctcga acacggcgcg gtcagccgcc
    10321 aaaccgtcta tgagatggcg cgcggcgcga aagccgtggc gcaggcggat tacgccgtcg
    10381 gtatttccgg catcgccgga ccgggcggcg gcagcgaaag caaacccgtc ggcacggttt
    10441 ggttcgggtt tgcctttccg ggcggaagtt gcgaagcaat gcgccgtttt gacggcaacc
    10501 gcgaatccgt ccgcgcgcag gcggtcgcct tcgcgttgga acggttggcg gggctgattg
    10561 aaaacggcgg cgatgccgtc taaacaaaat ctccgtctgg acaaaatccc cgccggataa
    10621 aaaataccgt ctgaaacgtt gcaggtttca gacggtattt tgtcgggtta ggcggcggtg
    10681 cggcttattt cactttactc ttcaacgcgc cgtagcctgc cgcgtccatt tgttccagcg
    10741 ggatgaattt caagctcgcg ccgttgatgc agtagcgcag tccgcctttg tcgcgcgggc
    10801 cgtcggggaa gacgtgtccc aaatgcgaat cggcggcgtg gctgcgcact tcggtgcggc
    10861 gcatgttgta gctgaaatca tcgtgttcgg taacggattt tgcatcaatc gggcgcgtga
    10921 agctcggcca gccgcagccg gaatcatatt tgtcggcgga gctgaacaaa ggttcgccgc
    10981 tgacaacgtc cacataaatg ccgggtttga acaaatggtc gtattcgtgg ctgaaggcgt
    11041 attcggtcgc gctgttttgg gtcacttggt attgctcttc ggtcagggtg cgtttgagtt
    11101 cggcatcact gggtttttta tacgttgccg catcgaagcc tttgccttgc ggggcggctt
    11161 tggttttgcc cggcagtggt tcgtcggctt tgcggatatc gatgtggcag tagccgttgg
    11221 ggtttttaat caggtagtcc tgatggtatt cctcggcatc gtagaagttt ttcagcggct
    11281 cgttttcaac aacgaggggc agttggtatt tttgctgctc gcgtttgagg gcggcggcga
    11341 tgacggcttt ttcggcgggg tcggtgtagt acacgccgct gcggtattgc gtaccggtgt
    11401 cgttgccctg tttgttgagg ctggtcggat caacgacgcg gaagaaatat tgcaggatgt
    11461 cgtcgaggct gagtttgtcg gcatcgtagg taactttgac ggtctcggcg tgccccgtat
    11521 ggcggtagga cacgtcttcg tagctcggat ttttcgtgtt gccgttggcg tagccggata
    11581 ccgcgtcaac cacgccgtcg atgcgttgga aataggcttc caagccccag aagcagccgc
    11641 cggcgaggta aatggtgcgc gtgttcatga tttttgaatc ctttttctga gtgtcgggtt
    11701 tgtagaacga atgtttcaag ctgcccaaat cggcattcgg gtcgcggatt aacgccaacg
    11761 cctgcgcttc gttgatgctg cctttgacga tgcgctgcac gtcgccgtct ttaccgatta
    11821 acgcccacga ggggtaaacg ctgatattca ggctttgggc gatcgtgccg ccgttgtcgg
    11881 ttacgacggg cagcttggga taattcaaac cggcatacca tttttggaag tcgccgtctt
    11941 ttttctcgtg caaaaagccc ggagacgcga cggtaatcag gttggcggag ctgaattttg
    12001 catcttgcgc ccatttttcg gtctgtccca attcggacag acacaaagga caccagctcg
    12061 cccaaaattt aatcagcgtc ggtttgtctt ttttcaagta aacactggcg gggcggttgt
    12121 ccgcagtttt caaagtggat aaagtgtgcg gcacggtcgc ggctccggca tcgacgattt
    12181 tgggcgaaca agcacccagc gcaagcaggc agccgaactt ggcgcaaagg gaaaagaaag
    12241 tacggtgttt cattttgagt ttcctgtgtg gacggtttgc atgattagac gtttgagatg
    12301 ccgaaacctt acagctcgga ttttcagaca accttgccgc gtaaaatacg ctacaatacg
    12361 ccctgtttca agtttctaaa attaaaagga aaattcaatg ttcagcttct tccgtcgcaa
    12421 gaaaaaacag gaaacgccgg ctcccgagga ggctcaagtt caggaaactg cagcaaaagc
    12481 agaatccgaa gttactcaaa tagttgaaaa tattaaagaa gaagtcgaat ctttaacgga
    12541 aagcgtcaaa gggcaggtcg aatcggctgt tgaaaccgtc agcggtgcgg ttgaacaagt
    12601 aaaggaagcc gttgccgaga tgctgtctga agcagaggaa gcggcggaaa aagcagcgga
    12661 acaagtcgaa gcggcaaaag aagccattgc cgaaaccgtc ggcgaggctg tcgggcaagt
    12721 tcaagaagcc gttgcaacaa ctgaagaaca caagctcggt tgggcggcgc gtttgaaaca
    12781 aggtttgacc aaatcgcgcg acaaaatggc gaaatcgctg gcgggcgtgt tcggcggcgg
    12841 acaaatcgac gaagatttgt acgaagagct ggaaaccgtg ctgattacca gcgatatggg
    12901 catggaagcc accgaatacc tgatgaaaga cgtgcgcgac cgcgtcagcc tcaaagggct
    12961 gaaagacggc aacgaattgc gcggcgcgct gaaagaagcc ttgtacgacc tgattaagcc
    13021 tctagagaaa ccgctggttt tgcccgaaac caaagagccg tttgtcatca tgcttgctgg
    13081 catcaacggc gcgggcaaaa ccacgtctat cggcaaactc gccaaatatt tccaagcgca
    13141 gggcaaatcc gtattgctgg cggcaggcga tactttccgc gccgccgcgc gtgagcagct
    13201 tcaagcttgg ggcgagcgca acaacgttac cgtgatttcg caaaccacgg gcgattccgc
    13261 cgccgtgtgc ttcgatgccg tccaagccgc caaagcgcgc ggcatcgaca tcgtgctggc
    13321 cgacaccgcc ggccgcctgc ccacgcagct tcatttgatg gaagaaatca aaaaagtgaa
    13381 acgcgtgctg caaaaagcca tgcccgacgc gccgcacgaa atcatcgtcg tgcttgatgc
    13441 caacatcggg caaaacgccg tcaaccaagt caaagccttt gacgacgcat tagggctgac
    13501 cggtttaatc gtgaccaaac tcgacggcac ggcaaaaggc ggcatccttg ccgcgcttgc
    13561 ctccgaccgc ccagttcccg tccgctacat cggcgtgggc gaaggcatag acgatttgcg
    13621 cccgtttgac gcgcgcgcgt ttgtggacgc actgctggat tgagccgaaa tgccgtccga
    13681 aaacagcaga ccgatgccgt cattcccgcg caggcgggaa tccagacctt gggataacgg
    13741 caatattcaa agtttataaa agacccgtca ttcccgcgca ggcgggaatc cagaacgtaa
    13801 aatctaaaga aaccgtgttg taacggcaga ccgatgccgt cattcccgcg taggcgggaa
    13861 tctaggcctt agaacaacag taatattcaa aggttagctg aagctttaga gattctggat
    13921 tcccactttc gtgggaatga cgggatttta ggtttctgat tttggttttc tgtttttgta
    13981 ggaatgatga aattttgagt tttaggaatt tatcggaaaa aacagaaacc gctccgccgt
    14041 cattcccgcg caggcgggaa tccagacctt agaacaacag taatattcaa agattataaa
    14101 agacccgtca ttcccgcgca ggcgggaatc tagaatcatc ggcacggaaa cttatcgggt
    14161 aaacggtttc ttgagattcc gcgtcctaga ttcccacttt cgtgggaatg acgggatttg
    14221 agattgcggc atttatcgga aaaaacagaa accgctccgc cgtcattccc gcgtaggcgg
    14281 gaatctaggt ttgtcggtgc ggaaacttat cgggtaaaac ggtttcttta gattttgcgt
    14341 tctagattcc cactttcgtg ggaatgacga agagttgcgg gaatgatgga aagctatggg
    14401 aataacgaag ggttaaagta atcacgggat ggtgttcgcg ggaatataaa tttaaataat
    14461 tcaaaagggt attatatgca gcctgcggtt tatattttag caagccaacg taatggcacg
    14521 ttatacattg gcgttacatc tgatttggtg caacgtattt accaacatag ggagcatttg
    14581 attgagggat ttacatcacg gtacaacgtt actatgctgg tttggtatga actgcatcct
    14641 acgatggaga gcgcaattac tcgggaaaaa cagttgaaga aatggaacag ggcttggaaa
    14701 ttgcaactga ttgaagaaaa taatgtttct tggcaggatt tatggtttga tattatttag
    14761 cccgtcattc ccgcgcaggc gggaatccag accttagaac aacagcaata ttcaaaggtt
    14821 agctgaagct ttagagattc tggattccca ctttcgtggg aatgacggga tttgagattg
    14881 cggcatttat cggaaaaaac agcaaccgct ccgccgtcat tcccgcgcag gcgggaatcc
    14941 agaccttaga acaacagcaa tattcaaaga ttataaaaga cccgtcattc ccgcgtaggc
    15001 gggaatccag actgtcgggc atctgcagcg gtttgctaaa aaacgcttta ccgtgatcag
    15061 tgtgcaaagt taaaatgggg aagtaagctt ttcaatcagc aattcggcgg gcgcggaatc
    15121 gggcggttta ccgaacctcg gcgttcgcgg cgcgccgccc cgtcccgtga aggcaaactc
    15181 aaggaataaa agatgaataa aacttggaaa cggcaggttt tccgccatac cgcgctttat
    15241 accgccatat tgatgttttc ccataccggc gggggggggc gcaagcgcaa acgtattcat
    15301 acgctcttgt aatgaacgga caacagctgc ctgaggtaaa gtgggggaat tcatataatc
    15361 aattgacgca caaaaacaat acccgccaag ctacctttca ttcatatttt cagggagcta
    15421 gaaaaaaaac tactttctca ttcaataata ccgatgaagt tgttgctcaa aaaggcgata
    15481 ctgtcgtttt cggcgcggcg acctacctgc cgccctacgg caaggtttcc ggttttgatg
    15541 aaagaaagct gaaagagcgc accaatgccc ttaattggat taatacgact cgcccggggt
    15601 tggtaggcta ccactaccaa gatagcacat gctccagcgg aaactgtcct gaacttagct
    15661 ataaaaccca atttaccttc ggtcattcca gtttggcaaa aaagacaaac ggcggcaagc
    15721 tggatatata cgaagacaaa agccgcgacg gttcgcccat ttacaaattg caaggttatt
    15781 cttggttggg cgtgtctttc aatttgagcg gcgaaagcac cgccgaatca aagaaactca
    15841 agaacttggt atcttctttt agcgaggaag taacgcagaa caatggtgcg gacagccaac
    15901 acaaagacaa aaacctcgtc tatacgacag gcgatggccg taataataat aaaacccatc
    15961 aggacaaaca ccacgccgtc gccttttatc tgaacgccaa actgcacctg ctggataaac
    16021 aacaaatcaa aaatatcacg caaggcagtg aacttaattt gggtgtcttg aaaacgcgca
    16081 tcgagccgac ggacgcgtgg aagaataaga gacatctcgt tattaatgct gattgggagt
    16141 ttaaagatac cggaatagtc agcgtcaaac tcaaattgcc ggaagtcaaa gcaggccgct
    16201 gcatcaataa accgaacccc aataaaaaca gcaaagccct ttcgccggca ctgactgccc
    16261 ccgcgctgtg gttcggacct gtgcaaaatg gtaaggtgca gatgtattcc gcttcggttt
    16321 ccacctaccc cgacagttcg agcagccgca tcttccttca aaatctgaaa agaaaaaacg
    16381 accccaacaa acccggccgc tattccctcg cagacttgag tgcgttggat attcaaagta
    16441 aagagccgac tttcacaggg cggcaaacaa tcatccgatt ggatggcggc gtacggcata
    16501 tccaactgga taaaagcaat gaggccaccg gtttaaatgg aaatgacggc aaaaacgaaa
    16561 ctttcggcat tgttagcgaa gggagcttca tgcctgatac cagcgagtgg aaaaaagtat
    16621 tgctgccttg gacggttcgg gattctgctg atgacagtaa atttaaagca ttcaacaaag
    16681 aagaaaacaa cggcaacaag ccaaaataca gtcaaaaata ccgcatccgc gacaacggca
    16741 acaacaacaa tcgcaatttg ggcgacatcg tcaacagccc gattgtggcg gtcggcgagt
    16801 atttggctac ttccgccaac gacgggatgg tgcatatctt caaaaaaggc aacggcgggg
    16861 atgaccgcag ctacaatctg aagctcagct acatccccgg cacgatgccg cgcaaggata
    16921 ttgaaagcaa agaatccacc ctcgccaaag agctgcgcgc ctttgccgaa aaaggctatg
    16981 tgggcgaccg ctacggcgtg gacggcggct ttgtcttgcg caaagtcgaa cggaacggga
    17041 aagaccatgt gtttatgttc ggcgcgatgg gctttggcgg cagaggcgcg tatgccttgg
    17101 atttgaccaa aatcgacagc aataacctga ccggcgtttc catgtttgat gtcccaaacg
    17161 acaaaaataa caataagaat gacaataatc gcgtggaatt aggctacacc gtcggcacac
    17221 cgcaaatcgg caaaacccac gacggcaaat acgccgcttt cctcgcctcc ggttatgcga
    17281 ctaaaaccat tgacgaccaa caaaataaaa ccgcgctgta tgtgtatgat ttggaaagca
    17341 gcggtacgct gattaaaaaa atcgatgtac ccggcggcaa gggcgggctt tcgtccccca
    17401 cgctggtgga taaagatttg gacggcattg tcgatatcgc ctatgccggc gatcgcggcg
    17461 ggaatatgta ccgctttgat ttgagcagcg acaatccgtc cagctggact gtacgcacta
    17521 ttttcagcgg caacaaaccg attacttccg cgcccgccat ttcccaactg aaagacaaac
    17581 gcgtggttat cttcggcacg ggcagcgatt tgagtgagga tgatgttgat aaaacggacg
    17641 aacaatatat ttacggtatc tttgacgacg atacggcgac gacgggtcct gtaaacttca
    17701 gcggtacggg aggcgggctg ctcgagcaag tgcttactga ggaaaataaa accttattcc
    17761 tgaccgatta caagcgatcc gacggctcgg gcagcaaagg gtgggtagtg aaattgaagg
    17821 acggacagcg cgttaccgtc aaaccgaccg tggtattgcg taccgccttt gtaaccatcc
    17881 gcaaatataa
//
LOCUS       DAXIDM010000037        17530 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000037 DAXIDM010000000
VERSION     DAXIDM010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 17530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17530
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.037"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..1016
                     /gene="mafB"
                     /locus_tag="ACFOAE_001016"
     CDS             <1..1016
                     /gene="mafB"
                     /locus_tag="ACFOAE_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polymorphic toxin MafB class 1"
                     /protein_id="HFC6884520.1"
                     /translation="EEHAPFDNHAADSASKEQGNVDDGFTVYRLNWEGHEHHPADAYD
                     GPKGGNYPKPTGARDEYTYHVNGTARSIKLNPTDTRSIRQRISDNYSNLGSNFSDRAD
                     EANRKMFEHNAKLDRWGNSMEFINGVAAGALNPFISAGEALGIGDILYGTRYAIDKAA
                     MRNIAPLPAEGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAK
                     VAKLAKAAKPGKAAVSGDFSDSYKSAPMGSRYNQMNQPRNPNYQSVRNIATEINGRQY
                     SGHALDRMQDRGIMPSVIENTIQTGQQIGIKDGKTSYYDSKNNVKVIINQSGGVVTTT
                     YGK"
     gene            1006..1506
                     /locus_tag="ACFOAE_001017"
     CDS             1006..1506
                     /locus_tag="ACFOAE_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884521.1"
                     /translation="MENRFAKIVKDIFSFAQFVSETENEIPNQSSRYYDCWWELEILN
                     ASALEDWEISGKPEKWEKWTGKYQTEALQLVKNLFAEEVPENNIVCDISHFLHFADRA
                     EADIPNQSRLYAEYWWEMEMFKMSVLEDWERSGKPLDWEKWQRQYRSEAFELVKKLHQ
                     SKRKPD"
     gene            1599..2393
                     /gene="mafB"
                     /locus_tag="ACFOAE_001018"
                     /pseudo
     CDS             1599..2393
                     /gene="mafB"
                     /locus_tag="ACFOAE_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951255.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 1"
     gene            2383..2931
                     /locus_tag="ACFOAE_001019"
     CDS             2383..2931
                     /locus_tag="ACFOAE_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HFC6884522.1"
                     /translation="MDYNQTVLSHLQKFWKHHDIKGFTWTLGRIVEELPDFQVFQVIP
                     NHEDEPWVYVSSGIGQFLGQEFFIISPFETPEHIETLAMLASASMHYPDQFQLGKTVN
                     IGRPWIEQSSFRHFLISLPYPYGQELEYMDNVRFFWLLPITQTERLFLNTHSVEELET
                     KFDEAGIDYLDINRASTVWQAG"
     gene            3228..3581
                     /locus_tag="ACFOAE_001020"
     CDS             3228..3581
                     /locus_tag="ACFOAE_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884523.1"
                     /translation="MGIKNEQIIICKKYNTEIYPVSDVSKIGVAENVKQTGLYPINGL
                     RHRPKGDTNGWYIWAGENFSYDKNFFLPLHTFHLQIWRPEIIPFLTLPPGYRFLIGEN
                     GYEDVWFDELLLNDN"
     gene            3571..3894
                     /locus_tag="ACFOAE_001021"
     CDS             3571..3894
                     /locus_tag="ACFOAE_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HFC6884524.1"
                     /translation="MIIDKKSTSDVLKQYQELGFDLTKPMIIEFFIGGSQKNLQSIES
                     RLISYRQDFQISIEQDEFGEMWTCYCSVNIVPSLENILAIETTLFGIAQKNDCNYEGF
                     GSYGN"
     gene            3953..4180
                     /locus_tag="ACFOAE_001022"
     CDS             3953..4180
                     /locus_tag="ACFOAE_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884525.1"
                     /translation="MDIKFNTLGVILNGVNPEEKFIKIIDDQENTGGFLILLSSNDKF
                     SSFDSYDDWVENLEILKEYLQESHWIIKWVG"
     gene            4308..4850
                     /locus_tag="ACFOAE_001023"
     CDS             4308..4850
                     /locus_tag="ACFOAE_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="suppressor of fused domain protein"
                     /protein_id="HFC6884526.1"
                     /translation="MINHIEKYIGTISHGSKSDSGSQYKLNIAAIPSSPNRDLKTYIT
                     LGLSKHDLNYKSRSEILFVCSLKYDENQIFPFLRWLAETIIENKKILLRGQVVYLPRS
                     IVDSTKMDALYVSAPFYFDDDFQVCYGEHYNIVFPLLVPLYKQEAEWVEKKGWNAFEQ
                     FLLDNEVGNLSDMNRKPFTW"
     gene            4986..5660
                     /locus_tag="ACFOAE_001024"
     CDS             4986..5660
                     /locus_tag="ACFOAE_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HINT domain-containing protein"
                     /protein_id="HFC6884527.1"
                     /translation="MVKTADGYKAIAHIQAGDRVLSKDEASGKTGYKPVTTRYGNPYR
                     ETVYIEISDGIGNNQTLVSNKIHPFYSQGKWIQAGRLKKGDTLLSESGAKQTVQNITL
                     KQQPLKAYNLTVADWHTYFVKGNQAETEGVWVHNACPIKPKPTNHAQQRKEEAKNDSH
                     RSVGDSNRVVREGKQYLDSDTGNHVYVKGDKVVILTPDGRQVTQFKNSKANTSKRVKN
                     GKWTPK"
     gene            5638..5919
                     /locus_tag="ACFOAE_001025"
     CDS             5638..5919
                     /locus_tag="ACFOAE_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884528.1"
                     /translation="MGNGHQNNRSPLEKRIFYLEHSGQYLMICALSDYSQNKHTVVMA
                     NFLYPNEKMDWRNLDDLFNELVLEELQSSFMDWYPTIEEAISHHLEDFS"
     gene            6298..7431
                     /locus_tag="ACFOAE_001026"
     CDS             6298..7431
                     /locus_tag="ACFOAE_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884529.1"
                     /translation="MFKKFKPVLLSFFALVFAFWLGTGIAYEINPRWFLSDTATEIPE
                     NPNAFVAKLARLFRNADRAVVIVKESMRTEESLAGAVDDGPLQSEKDYLALAIRLSRL
                     KEKAKWFHVTEQEHGKEVWLDYHIGEGGLVAVSLSQRSPEAFVNAEYLYRNDRPFSVN
                     VYGGTAHGENYETTGEYRVVWQPDGSVFDAAGRGKIGEDVYEHCLGCYQMAQVYLAKY
                     RDVANDEQKVWDFREESNRIASDSRDYVFYQNMRELMPRGMKANSLVVGYDADGLPQK
                     VYWSFDNGKKRQSFEYYLKNGNLFIAQSSTVALKADGVTADIQTYHAQQTWYLDGGRI
                     IREEKQGDRLPDFPLNLENLEKEVRRYAEAAARRSGGRRDLSH"
     gene            complement(7518..7793)
                     /locus_tag="ACFOAE_001027"
     CDS             complement(7518..7793)
                     /locus_tag="ACFOAE_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884530.1"
                     /translation="MNESEVVLTPEQIQTLRGYASRGDTYGGWRYLANLGDRYADDAA
                     AIVGKDANLNGLNLWMKKGVENLWDDTVGKKIRLMCISVFWIVVFNL"
     gene            complement(7810..8577)
                     /locus_tag="ACFOAE_001028"
     CDS             complement(7810..8577)
                     /locus_tag="ACFOAE_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RTX iron-regulated FrpC family protein"
                     /protein_id="HFC6884531.1"
                     /translation="MRPYATTIYQLFILFIGSVFTMTSCEPVNEQTSFNNPEPMTGFE
                     HTVTFDFQGTKMVIPYGYLARYTQDNATKWLSDTPGQDAYSINLIEISVYYKKTDQGW
                     VLEPYNQQNKAHFIQFLRDGLDSVDDIVIRKDACHLNQDLGKSLLDLGFKKIPSVYPE
                     YEAYEDKRSIPENPYIHELQYIKKGENPAIITHQNYHRYGENDYSTDIGSCINGFTVQ
                     YYPFIREKQQLTQQELVGYHQQVEQLVQSFVNNSSKK"
     gene            complement(8976..9251)
                     /locus_tag="ACFOAE_001029"
     CDS             complement(8976..9251)
                     /locus_tag="ACFOAE_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFC6884532.1"
                     /translation="MNASNWSVYLILCENSAFYCGISPNPQQRLAAHTTGKGAKYTRV
                     FKPVAMRIVAGGMDKGTALRQEIAVKKLTAAQKRQLWEQAEKMPSET"
     gene            complement(9248..10531)
                     /locus_tag="ACFOAE_001030"
     CDS             complement(9248..10531)
                     /locus_tag="ACFOAE_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC6884533.1"
                     /translation="MTASKSGFIGQIFSRNMLVCIFTGFTSGLPLYFLINLIPAWLRS
                     EQVDLKSIGLMALIGLPFTWKFLWSPLMDAVRLPVLGRRRGWMLLTQAGLLAALAAYA
                     FLNPRNHLPLIAGLSVLVAFFSASQDIVLDAFRREILSDEELGLGNSVHVNAYRIAAL
                     IPGSLSLVLADRMPWSEVFVITSLFMLPGLLMTLFLAREPVLPPAVPKTLKQTVVEPF
                     KEFFTRKGIASAVCVLLFIFLYKLGDSMATALATPFYLDMGFSKTDIGLIAKNAGLWP
                     AVAAGILGGVWMLKIGVNKALWIFGAVQAVTVLGFVWLAGFGHFDTVGTGERLMLAAV
                     IGAEAVGVGLGTAAFVSYMARETNPAFTATQLALFTSLSAVPRTVINSFAGYLIEWLG
                     YVPFFQLCFILALPGMLLLLKVAPWNGEKTQDAGR"
     gene            complement(10687..12105)
                     /gene="glnA"
                     /locus_tag="ACFOAE_001031"
     CDS             complement(10687..12105)
                     /gene="glnA"
                     /locus_tag="ACFOAE_001031"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFC6884534.1"
                     /translation="MSIKNAVKLIEESEARFVDLRFTDTKGKQHHFTVPARIVLEDPE
                     EWFENGQAFDGSSIGGWKGIQASDMQLRPDASTAFVDPFYDDVTVVITCDVIDPADGQ
                     GYDRDPRSIARRAEAYLKSSGIGDTAYFGPEPEFFVFDGVEFETDMHKTRYEITSESG
                     AWSSGLHLDGQNTGHRPTVKGGYAPVAPIDCGQDLRSAMVNILEELGIKVEVHHSEVG
                     TGSQMEIGTRFATLVKRADQTQDMKYVIQNVAHNFGKTATFMPKPIMGDNGSGMHVHQ
                     SIWKDGQNLFAGDGYAGLSDTALYYIGGIIKHAKALNAITNPSTNSYKRLVPHFEAPT
                     KLAYSAKNRSASIRIPSVNSSKARRIEARFPDPTANPYLAFAALLMAGLDGIQNKIHP
                     GDPADKNLYDLPPEEDALVPTVCASLEEALAALKADHEFLLRGGVFSKDWIDSYIAFK
                     EEDVRRIRMAPHPLEFEMYYSL"
     gene            12189..12338
                     /locus_tag="ACFOAE_001032"
     CDS             12189..12338
                     /locus_tag="ACFOAE_001032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884535.1"
                     /translation="MPSETRPASNFKLENIVSDGKIVNNMLLFVCSKAEYPPFCPNAD
                     KTDAV"
     gene            complement(12379..12756)
                     /locus_tag="ACFOAE_001033"
     CDS             complement(12379..12756)
                     /locus_tag="ACFOAE_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-adhesin E family protein"
                     /protein_id="HFC6884536.1"
                     /translation="MKKMLCLAVFALGLATPAVAADWVLVDSNTATFGDADSRTDNSA
                     WFETRFAKPQKYGNGKFFNTAKTLEEMDCSGKRFRILTATWYSKSGNSIASYTPSYAE
                     WNYVIPGTLGEAQYKFVCNGYPR"
     gene            12928..13737
                     /gene="aroE"
                     /locus_tag="ACFOAE_001034"
     CDS             12928..13737
                     /gene="aroE"
                     /locus_tag="ACFOAE_001034"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFC6884537.1"
                     /translation="MTALPRYSVFGNPVAHSKSPQIHQQFALQEGVDIEYERICADIG
                     GFAQAVSTFFETGGCGANVTVPFKQEAFHLADEHSERALAAGAVNTLIPLKNGKLRGD
                     NTDGLGLVGDIVKVQHTEIEGKNILLLGAGGAVRGVIPVLKEHRPARIVIANRTRAKA
                     EELSRLFGIEAVPMADLNGGFDIIINGTSGGLNGQIPDIPPDIFQNCALAYDMVYGCA
                     AKPFLDFARQSGAKKTADGLGMLVGQAAASYALWRGFTPDIRPVIEYMKAM"
     gene            13739..14440
                     /gene="mtgA"
                     /locus_tag="ACFOAE_001035"
     CDS             13739..14440
                     /gene="mtgA"
                     /locus_tag="ACFOAE_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009274 - peptidoglycan-based cell wall
                     [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HFC6884538.1"
                     /translation="MFRIVKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMR
                     MKQFEQEGRDVALDYRWMPYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNR
                     NSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSI
                     EWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIV
                     LRRMGSAELPESDTD"
     gene            complement(14766..14841)
                     /locus_tag="ACFOAE_001036"
     tRNA            complement(14766..14841)
                     /locus_tag="ACFOAE_001036"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14806..14808),aa:Phe,seq:gaa)
     gene            complement(15032..15766)
                     /gene="lptB"
                     /locus_tag="ACFOAE_001037"
     CDS             complement(15032..15766)
                     /gene="lptB"
                     /locus_tag="ACFOAE_001037"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HFC6884539.1"
                     /translation="MSANVSRLVVQNLQKSFKKRQVVKSFSLEIESGEVVGLLGPNGA
                     GKTTSFYMIVGLIAADAGSVMLDGQELRHLPIHERARLGVGYLPQEASIFRKMTVEQN
                     IRAILEISTKDKSRIDGEVEKLLADLNIERLRNNPAPSLSGGERRRVEIARVLAMKPH
                     FILLDEPFAGVDPIAVIDIQKIIGFLKSRGIGVLITDHNVRETLSICDRAYIISDGTV
                     LASGKPDDLVGNEQVRSVYLGKNFKY"
     gene            complement(15840..16370)
                     /gene="lptA"
                     /locus_tag="ACFOAE_001038"
     CDS             complement(15840..16370)
                     /gene="lptA"
                     /locus_tag="ACFOAE_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_function: GO:0001530 - lipopolysaccharide binding
                     [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide transport periplasmic protein
                     LptA"
                     /protein_id="HFC6884540.1"
                     /translation="MIQKICKLFVLIAFFSASPAFALQSDSRQPIQIEADQGSLDQAN
                     QSTTFSGNVVIRQGTLNISAARVNVTRGGKGGESVRAEGSPVRFSQTLDGGKGTVRGQ
                     ANNVAYSSAGSTVVLTGNARVQRGGDVAEGAVITYNTKTEVYTISGSTKSGAKSASKS
                     GRVSVVIQPSSTQKSE"
     gene            complement(16351..16932)
                     /gene="lptC"
                     /locus_tag="ACFOAE_001039"
     CDS             complement(16351..16932)
                     /gene="lptC"
                     /locus_tag="ACFOAE_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015920 - lipopolysaccharide transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HFC6884541.1"
                     /translation="MKVRWRYGIAFPLILAVALGSLSAWLGRISEVEIEEVRLNPDEP
                     QYTMDGLDGRRFDEQGYLKEHLSSKGAKQFPESSDIHFDSPHLVFFQEGRLLYEVGSD
                     EAVYHTENKQVLFKNNVVLTKTADGKRQAGKVEAEKLHVDTESQYAQTDTPVSFQYGA
                     SHGQAGGMTYDHKTGMLNFSSKVKATIYDTKDM"
     gene            complement(16929..17465)
                     /locus_tag="ACFOAE_001040"
     CDS             complement(16929..17465)
                     /locus_tag="ACFOAE_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KdsC family phosphatase"
                     /protein_id="HFC6884542.1"
                     /translation="MQAISPELQARAAKIKLLILDVDGVLTDGRIFIRDNGEEIKSFH
                     TLDGHGLKMLQASGVQTAIITGRDAPSVGIRVKQLGINYYFKGISDKRAAYEELRAQV
                     GVEEAECAFVGDDVVDLPVMVRCGLPVAVPDAHWFTLQHAAYIAKRPGGAGAVREVCD
                     LIMQAQGTLGAALNEYIK"
BASE COUNT         4829 a         4103 c         4173 g         4425 t
ORIGIN      
        1 acgaagaaca cgcccccttc gacaaccacg ccgccgacag cgcaagcaaa gaacaaggca
       61 acgttgacga cggctttacc gtataccggc tcaactggga aggacacgaa catcatcccg
      121 ccgatgccta cgacggcccg aagggcggca attaccccaa acctacgggc gcacgcgacg
      181 aatacaccta tcacgtcaac ggcacagcac gcagcatcaa actcaatccg accgacaccc
      241 gcagcatccg gcaacgcata tccgacaatt acagcaacct cggcagcaat ttctccgacc
      301 gcgccgatga agccaacaga aaaatgttcg agcacaatgc caagctcgac cgctggggca
      361 acagcatgga gtttatcaac ggcgtcgccg ccggcgcgct caaccccttt atcagcgcgg
      421 gcgaagcctt gggcataggc gacatactgt acggaacgcg ctatgccata gacaaagccg
      481 caatgcgcaa catcgccccc ttacccgccg agggcaaatt cgccgtcatc ggcggcttgg
      541 gcagcgtggc gggctttgaa aagaatacgc gcgaagccgt tgaccggtgg atacaggaaa
      601 accccaatgc cgccgaaacc gtcgaagccg tcttcaacgt tgccgctgcc gccaaagtcg
      661 cgaagttggc aaaggcggca aaaccgggga aagctgcggt tagcggggat ttttcagact
      721 cttataaatc tgctccaatg ggaagtagat ataatcagat gaatcaacct agaaatccta
      781 attatcaatc agtaagaaat atagcaacgg aaataaatgg aagacaatat tctggtcatg
      841 ctcttgatag aatgcaggat cgagggatta tgccgtctgt tattgaaaat accatacaaa
      901 caggacaaca aatcggtatc aaagatggca aaacttcata ttatgattcc aaaaacaatg
      961 ttaaagttat tattaatcaa tctggagggg tagttacaac aacctatgga aaatagattt
     1021 gcaaaaatcg ttaaggatat ttttagtttt gcccaatttg tttccgaaac agaaaatgag
     1081 attcctaacc aatcctctcg ttattacgac tgttggtggg aattggaaat cttgaatgct
     1141 tccgcattgg aagattggga aatatcggga aagcctgaaa aatgggagaa atggacagga
     1201 aaatatcaga ccgaagcgtt acagttagtc aagaatctat ttgccgaaga agttcctgaa
     1261 aataatatag tttgcgatat ttctcatttt ttgcattttg ccgatcgggc agaagccgac
     1321 attcccaatc aatcacgttt atatgccgaa tattggtggg aaatggaaat gttcaaaatg
     1381 tcggttttag aagattggga acgctcggga aagccgttag attgggaaaa gtggcaaagg
     1441 caatatcgat ctgaagcatt tgaattagtt aaaaaattgc atcaaagcaa gcgtaagccg
     1501 gattgaaaac cggcaattcg atgccgtctg aagcgttatc cgactttcag acggcatttt
     1561 gatgaatgaa acaggatatt gagaactaag ttcttcaaaa atcctacacc tgctccttcc
     1621 acggcagcac cttggtcaaa acggcagacg gctacaaagc cattgcccat attcaagccg
     1681 gcgaccgcgt cctttccaag gacgaggcaa gcggagaaac gggatacaaa cccgttaccg
     1741 cccgatacgg caatccgtat caagaaaccg tttacattga aatttcagac ggcatcggca
     1801 acaaccaaac cctgatttcc aaccgcatcc acccgtttta ttcggacggc aaatggatta
     1861 aagcggaaga tttgaaagcg ggaagcaggc tgtttgccga aaacggtgcg gagcagacgg
     1921 ttcaaaacat taccctcaaa cagcagccgc tcaaagccta caatctgacc gttgccgact
     1981 ggcatactta cttcgtcaag ggcagtcagg cggaaacgga aggggtttgg gttcataatg
     2041 attgtccaac caaactaaaa ccgacagaac gttataatcg tcaaacgcat tatggaggtt
     2101 ctcaaacaga tggagcaagg gctcaggcag caagacaggc aggagaaggt aaaccttgtc
     2161 caacttgtgg tagaattcag atatttggta cgaaaaccgc accaagtccg caacatgaac
     2221 ccccattagt aaaacattac tatgaacatg gtggtcactc tatgagcaat gctgatcgag
     2281 cgaaacatgc cagggaaagc ataaaaggaa ctcaatgttt aacatgtcaa aggaaagagg
     2341 gtgcgatgat gtcaagatat tcgagagaac aggctaaaaa gcatggacta taaccaaact
     2401 gttttatctc acttgcaaaa attttggaaa catcatgata ttaaaggatt tacttggact
     2461 ttaggaagaa ttgttgaaga acttcccgat ttccaagttt tccaagtgat tcctaatcat
     2521 gaagatgagc cttgggttta tgtcagctct gggataggtc aatttttagg gcaggagttt
     2581 tttatcatca gcccgtttga aacacctgaa catattgaga ccttggcaat gctggcatct
     2641 gcaagtatgc attatcctga tcaatttcaa ttagggaaaa ccgtcaatat cggtagaccg
     2701 tggatcgagc aatcatcctt ccggcatttt ctgatttctc tgccttatcc ttatgggcaa
     2761 gagttggaat atatggataa tgtccgattt ttctggttat tgccaattac ccagacagaa
     2821 agacttttct tgaatactca ttcggtagaa gaattggaaa cgaaatttga tgaagcgggt
     2881 attgattatt tagatataaa tcgtgcgagt actgtctggc aggcaggata aaaattcggc
     2941 aatcaaaatg ccgtctgaaa caagtttgga ctttcagacg gtattctgat gaatggaaca
     3001 ggatactggg aactgagttc ttcaaaaatc ctatctccgt cccttatacg tcggtgcttt
     3061 agtcaaaacg gcagacggat gaaaaattat tgcccgtatc cttgccaaag atgaagcaag
     3121 atgaagccag gtaattgaat cggtacaagc gcaatgtccg acttgttctg caaaacaggg
     3181 agggagatta agccaatatt caaaagaaca gaaaaggaaa ctgagtaatg ggaataaaaa
     3241 atgaacaaat aataatttgt aaaaaatata atacagaaat atatcctgtt tccgatgttt
     3301 caaaaatcgg tgttgctgaa aatgtcaaac agacaggcct gtatccgatt aacgggttaa
     3361 ggcaccgtcc caaaggtgat actaacggtt ggtatatctg ggccggtgaa aacttctcct
     3421 atgataaaaa ttttttcctg cccttgcata cgttccattt gcaaatatgg cgacccgaaa
     3481 tcatcccctt tttaacactt ccgcccggtt accgtttttt aattggggaa aacggttatg
     3541 aagatgtatg gtttgatgaa ttgctattaa atgataattg acaaaaaatc tacttcagat
     3601 gtactgaaac aatatcaaga actagggttt gatttgacaa aacctatgat aatagagttt
     3661 tttataggag gttctcaaaa gaatctgcaa tcaatagaaa gccggctcat ttcttatcgg
     3721 caagattttc aaatcagtat tgaacaagat gaattcggag aaatgtggac ttgctattgt
     3781 tccgtcaata tcgtcccttc ccttgaaaac attttagcta ttgaaactac gttatttggt
     3841 attgcacaaa aaaatgattg taattatgaa ggttttggtt cgtatgggaa ctaacaaaaa
     3901 gtgtaggttg ggttgaaaaa accatattcc cattaaagat tagggtgtgt ctatggacat
     3961 aaaattcaat actttggggg ttatcctgaa tggggtcaat cctgaagaaa aattcataaa
     4021 aattattgat gatcaggaaa ataccggggg atttctgata ctgttatctt caaatgacaa
     4081 attctcatca tttgacagtt acgatgactg ggtcgaaaac ttagaaatat taaaagaata
     4141 cctgcaagaa tctcattgga taataaagtg ggtcggatag tcggcaaacg tagtccgtct
     4201 gaaacgcttt tacttttcag acggactttc tatcaatggg aacaaggcgt tttgtctcaa
     4261 tctggtctat gattatttcg atacagtgat gggaagctaa gaaaaatatg attaatcata
     4321 ttgaaaaata tataggcact atttctcatg gctcgaaaag tgattcggga agtcagtaca
     4381 aattaaatat cgcagctatt ccctcttccc ctaacaggga tttaaaaact tatattactt
     4441 tagggttaag caaacatgat ctgaattata aaagcagatc tgaaatactt tttgtatgtt
     4501 ctttaaaata tgatgaaaat cagatttttc catttttaag atggttggca gaaaccatca
     4561 ttgagaataa aaaaatcctt cttcgggggc aggttgttta tttgcccaga agcattgttg
     4621 attcaacaaa aatggatgca ctgtatgttt ccgccccatt ttatttcgac gatgattttc
     4681 aggtctgtta tggcgaacac tacaatatcg ttttcccttt gcttgtcccc ttgtataaac
     4741 aggaagccga atgggtggaa aaaaagggtt ggaatgcttt tgagcagttc ttgctggata
     4801 atgaagttgg caacctttcg gatatgaatc ggaaaccgtt tacttggtaa ggattttctt
     4861 aaatttaatc aaagtgccgt ctgaaaccgt gtttaatttt caggcgacct tccccttatt
     4921 ttaaacagga tattgggaac taagttcttc aaaaatccta cacctgctcc ttccacggca
     4981 gcaccttggt caaaacggca gacggctaca aagccattgc ccatattcaa gccggagacc
     5041 gcgtcctttc caaggacgag gcaagcggga aaacgggata caaacccgtt accacccgat
     5101 acggtaatcc gtatcgggaa accgtttaca ttgaaatttc agacggcatc ggcaacaacc
     5161 aaacccttgt ttccaataaa atccacccgt tttacagtca aggaaaatgg atacaggcag
     5221 gtcgtctgaa aaaaggcgac accctgcttt ccgaaagcgg tgcaaaacag acagttcaaa
     5281 acattaccct caaacagcag ccgctcaaag cctacaatct gaccgttgcc gattggcata
     5341 cttacttcgt taagggtaat caggcggaaa cggaaggggt ttgggttcat aatgcgtgtc
     5401 cgatcaaacc aaaaccaacc aatcatgccc aacaaagaaa agaagaagct aaaaacgatt
     5461 ctcatcgaag tgtgggagat tccaatcgtg tcgttcgcga aggaaagcaa tatttagatt
     5521 ccgacacagg aaaccatgtt tatgtaaaag gagataaagt ggttattcta actcctgatg
     5581 gaagacaggt aactcaattt aagaactcga aagccaatac gtcaaaaagg gtaaaaaatg
     5641 ggaaatggac accaaaataa tcgatctccc ttagaaaaaa gaatttttta tctggagcat
     5701 tcggggcagt atctgatgat ttgcgcccta tcagattact cccaaaataa acatactgtc
     5761 gttatggcga attttctcta tccaaatgaa aaaatggatt ggagaaattt agatgatttg
     5821 ttcaatgagt tggttttaga ggaattacag tcttcattta tggattggta tccgactatt
     5881 gaagaggcaa ttagccatca tttagaagac ttttcgtaac aagcataaat taaaggttgt
     5941 ctgaaactat gttcgatttt cgacgacatt ttcctcattg gagggggcgg caatttatgg
     6001 aaaatagatt tgaaaaaatc gttaaggata tttttagttt tacccaattt gttccgaagc
     6061 agaaaatgag attcccaccc catcctcccg ttatgacgac tgttggtggg aattggaaat
     6121 cttgaatgcc tctgcatttg aattagtcaa aaaattgaat caaagcaaac aagagtaaca
     6181 agctgcagcc tgcatagggg tttttaaagt acggcagcaa ccgtagatta aattaaaaat
     6241 caaacaatca aagctcgtct gatataatcg atatattctg ttaaacgaaa aataaatatg
     6301 tttaaaaaat tcaaaccggt actgttgtca ttttttgcac ttgtatttgc cttttggctg
     6361 ggaacgggta ttgcctatga gattaatccg cgttggtttt tgagcgatac ggcaactgaa
     6421 atacctgaaa atccgaatgc ttttgtggcg aaacttgccc gcctgttccg aaatgccgac
     6481 agggcggttg tcatcgtgaa ggaatcgatg aggacggagg aaagtcttgc cggagctgtg
     6541 gatgacggtc cgttgcagtc ggagaaggat tatctcgcgc tcgctatccg gctcagtcgt
     6601 ttgaaagaaa aggcgaaatg gtttcacgta acggagcagg aacatgggaa agaggtttgg
     6661 ctggattacc atatcggcga gggcggtttg gttgcggttt cgctttcgca acgctcgccg
     6721 gaagcgtttg ttaatgccga atatctgtat cggaacgatc gtccgttttc tgtaaatgtg
     6781 tacggcggaa cggctcacgg agaaaattat gaaacgacag gagaatatcg ggttgtttgg
     6841 caaccggacg gttcggtatt tgatgcggca gggcgcggga aaatcgggga agatgtttat
     6901 gagcattgcc tcgggtgtta tcagatggcc caggtatatt tggcgaaata ccgggatgtc
     6961 gcgaatgatg agcagaaggt ttgggacttc cgcgaagaga gcaaccggat tgcatcggac
     7021 tcgcgcgatt atgtgtttta tcagaatatg cgggaattga tgccccgagg gatgaaggca
     7081 aacagtcttg tggtcggcta tgatgcggat ggtctgccgc agaaagtcta ttggagtttc
     7141 gacaatggaa aaaaacgcca gagtttcgaa tattatttga aaaacggaaa tctttttatt
     7201 gcacaatctt cgacggtagc attgaaagcg gatggcgtaa cggcggatat acagacctat
     7261 catgcgcaac agacgtggta tttggatggc gggcggatta tccgcgaaga gaaacaggga
     7321 gacagactgc ctgattttcc tttgaacttg gaaaatttgg aaaaagaggt gcgccgttat
     7381 gcagaggctg cggcgagacg ttcgggcggc aggcgcgacc tttctcactg aacgcaaatg
     7441 ccgtctgaaa ccggttttca gacggcattg gagagtcaaa cgctttttgc aatgccgtat
     7501 atgccgaatc caattcgcta caaattgaaa accacaatcc aaaaaacaga aatacacatt
     7561 aaacggatct ttttaccgac cgtatcatcc cataggtttt ccacaccttt tttcatccat
     7621 aaattcaaac catttaagtt tgcatcctta ccgacaattg cagcagcatc atccgcataa
     7681 cggtcaccca aattagccaa ataacgccaa ccgccatagg tatcgccacg ggaagcataa
     7741 ccacgcaagg tttggatttg ttctggtgtt aaaacaactt cactctcatt cataataaga
     7801 tcctttaaat tattttttac ttgaattgtt tacaaaactc tgtaccaatt gctctacttg
     7861 ttggtgataa cctaccaact cctgctgtgt gagctgctgc ttttcccgaa taaacgggta
     7921 atactgtacc gtgaaaccgt taatacagga acctatatca gtactgtaat cgttctctcc
     7981 atacctatga tagttctgat gagtaataat cgccggattt tctcctttct taatatactg
     8041 tagttcatga atatatgggt tttcaggaat cgacctttta tcttcataag cttcatattc
     8101 aggatagaca gacgggattt ttttaaatcc caaatcaagc aacgattttc ctaagtcttg
     8161 attcaaatga cacgcatctt ttcggataac aatatcgtcc acgctatcca aaccgtcgcg
     8221 tagaaattgg ataaagtgcg ctttgttttg ctggttgtat ggctcaagaa cccagccttg
     8281 gtcggttttt ttgtaataga cgctaatctc tatcaaatta atggagtaag catcctgccc
     8341 gggcgtgtcg gaaagccatt ttgtggcatt gtcttgcgta taccgtgcaa gatagccata
     8401 ggggataacc attttggtgc cctgaaaatc aaatgtaacc gtatgttcaa atcctgtcat
     8461 tggctcggga ttgttgaaac tggtttgttc attaacaggt tcacatgagg tcatagtaaa
     8521 aacactccca ataaacaaaa taaaaagttg ataaatagta gtagcatatg gtctcataat
     8581 ttcaagccta gaaattagtt aaagaatata ttatggtaga tactaactct ttaagttgac
     8641 atattgtgcg atatcgaggg ctgtaccgta ttttcccatc gtattttccc atcgtatttt
     8701 cccgttcttt atatgagcgg caggcatcct cataaaagaa gggataccga taaggaaaaa
     8761 taccccagca taaaaaatat actgattaat caatacaaat ccaacaaaca gttcatcgta
     8821 ttcttttctg ttggcgtata aaaaatactg atatatgcct tcactttcat agggcgacgc
     8881 tttatgtacc gtcctgtgtg ttgaaacgtc ggttttcctt accgcctgcc ccgcttttcc
     8941 ctgattgctg ccaactgccg tccgaacttg aaccgtcagg tttcagacgg cattttttct
     9001 gcctgctccc acaattgccg tttttgtgcg gcggtcagtt ttttgacggc gatttcctgc
     9061 ctgagtgccg ttcctttatc catcccgcct gcaacgatac gcatcgccac cggtttgaat
     9121 acgcgggtat atttcgcgcc tttaccggtt gtgtgggcgg caagccgctg ttgcggattc
     9181 gggctgatgc cgcaatagaa cgcgctgttt tcacacaata tcaggtaaac gctccagttt
     9241 gacgcgttca tctgcctgca tcctgagttt tctccccgtt ccaaggcgca actttcagca
     9301 gcagcagcat acccggcagg gcaagtatga aacacagctg gaaaaacggt acatacccga
     9361 gccattcaat cagataaccg gcaaaggaat tgatgaccgt acggggaaca gcggacaggc
     9421 tggtaaacag tgcaagctgc gttgcggtaa atgcgggatt ggtctcgcgc gccatatacg
     9481 atacaaacgc cgccgtcccc aaacccacgc cgactgcctc tgcgccgata actgccgcca
     9541 gcatcagcct ctcgcctgtg ccgaccgtgt cgaaatgtcc gaaccctgcc agccatacaa
     9601 accccaaaac ggttacagcc tgcaccgcgc caaatatcca caaggctttg tttacgccga
     9661 ttttcagcat ccacacgccg cccaagatac ctgccgccac tgccggccac agtcctgcat
     9721 tttttgcaat caaaccgatg tctgtcttgc tgaaacccat atccagataa aacggcgttg
     9781 ccaacgcggt tgccatactg tcgccgagtt tgtaaaggaa gataaacagc agcacgcaca
     9841 ccgccgaagc gatgcccttg cgcgtaaaaa attctttaaa cggctctacc acggtctgct
     9901 tcaacgtttt aggaacggca ggcggcaaca cgggttcgcg cgcgagaaac agcgtcatca
     9961 gaaggccggg cagcataaat aatgaagtga taacaaatac ttctgaccac ggcatcctgt
    10021 ctgccaacac caaactcaat gaaccgggaa tcagggcggc aatccggtag gcgttcacat
    10081 gaaccgagtt gcccaaaccc aattcttcgt ctgacaaaat ctcgcgcctg aacgcatcca
    10141 atacaatatc ctgactggcg gaaaaaaaag cgacaagcac cgacaagccg gcaatcagcg
    10201 gcagatgatt acgggggttt aaaaaggcat aggccgccaa agccgccagc aaccctgcct
    10261 gcgtcagcag catccacccg cgccgccgtc ccaaaacggg cagcctgacc gcgtccatca
    10321 gcggcgacca caaaaatttc caagtaaacg gcagaccgat taacgccatc agcccgatgc
    10381 tcttcaaatc cacctgctcg ctgcgcaacc acgccggaat caggttaatc agaaagtaca
    10441 gcggcagccc cgaggtaaac cccgtaaaaa tacagacaag catattgcgg gaaaagattt
    10501 gcccgataaa acctgatttc gatgcagtca tcgttcgtgc agcccaaaaa aaacaaaagc
    10561 ctattgtagc aaatatcgcc cgcctgctga aaaatgccgc cccgcgccgc cggtttgccg
    10621 ttccaatgca aaatgccgtc tgaaactgtg ttcagacggc attgcttttc tgaaaaccag
    10681 acgtgcttac aggctgtaat acatttcaaa ttccagcggg tgcggcgcca tgcggatgcg
    10741 gcggacatct tcctctttaa aggcgatgta gctgtcgatc cagtctttgc tgaacacgcc
    10801 gccgcgcagg aggaattcgt ggtcagcttt gagcgcggcg agggcttctt ctaaagaagc
    10861 gcaaacggtc gggacgagcg cgtcttcttc cggcggcagg tcgtacaggt ttttatcggc
    10921 agggtcgccc ggatggattt tgttttgaat gccgtccaaa cccgccatca acagggcggc
    10981 aaatgccaaa tacgggttgg cggtcggatc ggggaaacgc gcttcgatgc ggcgcgcctt
    11041 gctgctgttc acggacggaa tgcggatgga agcggaacgg tttttggcgg agtatgccag
    11101 tttggtcggc gcttcaaagt gcggcacaag gcgtttgtag gagttggtgg acggattggt
    11161 aatcgcgttc agggctttgg cgtgtttgat gatgccgccg atgtaataaa gggcggtgtc
    11221 gctcaaaccg gcatagccgt cgccggcgaa caggttttga ccgtctttcc agatggattg
    11281 gtgaacgtgc ataccgctgc cgttgtcgcc cataatcggt ttgggcatga aggtggcggt
    11341 tttgccgaag ttgtgggcaa cgttttgaat cacatatttc atgtcttggg tttggtcggc
    11401 gcgtttaacc aaagtggcga agcgcgtgcc gatttccatt tggctgccgg taccgacttc
    11461 gctgtggtgg acttcgactt tgatgccgag ttcttccaaa atgttcacca tggcggagcg
    11521 caaatcttga ccgcagtcaa tcggggcaac gggcgcgtaa ccgcctttga cggtcggacg
    11581 gtggccagta ttttgaccgt ccaaatgcaa gccgcttgac catgcgccgc tttcggaagt
    11641 gatttcgtaa cgggttttgt gcatgtcggt ttcaaattct acgccgtcaa aaacgaagaa
    11701 ttcaggctcg gggccgaaat aggcggtgtc gccgatgccg gaagatttca aataggcttc
    11761 ggcgcggcgg gcgatggagc gcgggtcgcg gtcgtaaccc tgaccgtcgg cagggtcgat
    11821 gacgtcgcag gtaatgacga cggtaacatc atcataaaaa ggatcgacga aggctgtaga
    11881 cgcatcggga cgcagctgca tatcggaagc ctgaatgcct ttccagccgc cgatagacga
    11941 accgtcaaac gcctgaccgt tttcgaacca ctcttcgggg tcttccaaca cgatgcgcgc
    12001 aggcacggta aagtggtgct gcttgccttt ggtatcggta aagcgcaaat cgacaaagcg
    12061 ggcttcgctt tcttcaatca attttacggc gtttttaata gacatttttc agctcctgga
    12121 aaagggaaat agcaaaatat gcggaacgcg gcggcttgac gcaaagtcgg catgattcta
    12181 ccacgtccat gccgtctgaa actcgccctg cgtcaaattt caagctggaa aatatagttt
    12241 cagacggcaa gattgtcaac aatatgcttc tgtttgtctg ttcaaaagcg gaatacccgc
    12301 ccttttgtcc gaatgccgac aaaacagatg ccgtctgaaa gcagttcaga cggcatctgt
    12361 tgtttggttt gaaaacggtc agcgaggata gccgttgcag acaaatttgt actgagcctc
    12421 tccaagcgta ccgggaataa cataattcca ttcggcatag gatggtgtat aagaagcgat
    12481 agagtttccc gatttggaat accacgttgc cgtcaatatc ctaaaacgtt taccactgca
    12541 atccatttct tccaacgttt tagctgtatt aaaaaatttt ccattgccat acttttgcgg
    12601 cttggcgaac cttgtttcaa accatgcact gttgtccgta cggctgtctg catcaccaaa
    12661 cgtggcagta ttactatcta ccaataccca atccgccgcc accgccggcg ttgccaaccc
    12721 caatgcaaat actgccaagc acaacatctt tttcatgtcc gaccctctcg tccttgtcaa
    12781 caaaataaag ttaaattgta aaaaaaaaac gacttttttc aagagaaaaa tattccgtca
    12841 tgctatctga caaccgtttc agacggcatc gtttccatct gtacgccgcc gttataaaat
    12901 agccttcccg tcttttggaa cacgaccatg accgccctcc cccgttactc cgttttcggc
    12961 aaccccgttg cacacagtaa atcgccgcaa atccatcagc aatttgccct tcaggaaggc
    13021 gttgacattg aatacgaacg catttgcgcc gacatcggcg gttttgcaca ggcggtttcg
    13081 acattttttg aaacaggcgg ttgcggggca aacgttaccg taccgttcaa acaggaagcg
    13141 tttcatctgg cggacgagca ttccgaacgc gcattggcgg caggtgcggt caatacgctg
    13201 attccgttga aaaacggcaa gctgcgtggc gacaacaccg acggtttggg tttggtcggc
    13261 gatatagtga aggtgcaaca cacagaaatt gaaggcaaaa atatcctatt gctcggcgcg
    13321 ggcggcgcgg tgcgcggcgt gattccggtt ttgaaagaac accgtcctgc ccgtatcgtc
    13381 attgccaacc gtacccgcgc caaagccgag gaattgtcgc ggcttttcgg cattgaagcc
    13441 gtcccgatgg cggatttgaa cggcggtttt gatatcatca tcaacggcac gtcgggcggt
    13501 ctaaacggtc agattcccga tattccgccc gatatttttc aaaactgcgc gcttgcctac
    13561 gatatggtgt acggctgcgc ggcaaaaccg tttttagatt ttgcacgaca atcgggtgcg
    13621 aaaaaaactg ccgacggact gggtatgcta gtcggtcaag cggcggcttc ctacgccctc
    13681 tggcgcggat ttacgcccga tatccgccct gttatcgaat acatgaaagc catgtaatat
    13741 gttccgcatc gtcaaatggc tgattgccct gcccgtcggc atctttatct ttttcaatgc
    13801 ctatgtgtac ggcaacatca ttacctaccg cgccgtcgcg ccccatcgga ctgcctttat
    13861 gtcgatgcgg atgaagcagt ttgaacagga aggtcgcgat gtcgcactgg attaccgctg
    13921 gatgccctac aaacgcattt ccaccaacct gaaaaaagcc ctgattgctt ccgaagatgc
    13981 ccgtttcgcc gggcacggcg gcttcgattg gggcggcatt caaaacgcca tcaggcgcaa
    14041 ccggaacagc ggcaaagtga aggcgggcgg ctcgaccatc agccagcagc ttgccaaaaa
    14101 cctgttttta aacgaaagcc gcagctatat ccgcaaaggc gaagaagcgg cgattaccgc
    14161 gatgatggaa gccgttaccg acaaagacag gatttttgaa ctgtatttaa actcaatcga
    14221 atggcactac ggcgttttcg gcgcggaagc cgcgtcccgg tatttttatc aaatacccgc
    14281 cgccaagctg accaaacagc aggcggcaaa actgacggca cgcgtccccg ccccgctcta
    14341 ctacgccgac catccgaaaa gcaaacggct gcgcaacaaa accaatatcg tgctcagacg
    14401 catgggttcg gcagagttgc ctgaaagcga cacggactga ttgtttcaga tatggaaatg
    14461 ccgtctgaac tgcggttcgg acggcatatg ttttctggtt tttatagtgg attaacaaaa
    14521 atcaggacaa ggcgacgaag ccgcagacag tacaaatagc acggaatcga ttcacttggt
    14581 gcttcagcac cttagagaat cgttctcttt gagctaaggc gagccaacgc tgtaccggtt
    14641 taaatttaat ccactatacc tgcccgacag ccgcaaagac cgtatcatac atagcaggca
    14701 ttgcggtgcg ggattactgc cgcaaacggc aggcaaaaaa aaataaccgc ttataagcgg
    14761 ttttttggtg gccagaggcg gaatcgaacc gccgacacac ggattttcaa tccgttgctc
    14821 taccaactga gctatctagc ctttgtctgt ctcgttaaga gatgcgtatt aaaccaaatt
    14881 atgggacgac atgcaagcat atcgggcaat attctttgaa aacaggttta agtcaatgtt
    14941 ttaaatttga attaatttat gtaaaaacaa cataaatccg tatttttgcc gcctgcccga
    15001 cgatattagg tcgcccgtct gaaaaatatt ttcaatattt gaagttctta cccagataaa
    15061 cagaacgaac ctgttcgttt ccgaccaaat catcaggttt tcccgatgcc aacaccgtgc
    15121 cgtctgaaat aatgtaggcc cgatcgcaga tgctgagggt ttcgcgtacg ttgtggtcgg
    15181 taattaatac gccgataccg cgcgacttga gaaatccgat gattttttgg atgtcgatga
    15241 cggcgatggg atcgacgccg gcaaaaggct cgtccaacaa aataaaatgc ggtttcatgg
    15301 caagtacgcg ggcgatttcg acgcgtcggc gttcgccgcc cgacaaagat ggggcaggat
    15361 tattgcgcaa acgctcgata ttcaggtcgg caagcagttt ttcaacttcg ccgtcgatgc
    15421 ggcttttgtc tttggtactg atttctaaaa tggcgcggat gttttgttcg acggtcattt
    15481 tacggaaaat agaggcttcc tgcggtaggt agccgacacc caggcgggcg cgttcgtgta
    15541 tgggcaggtg acgcaattcc tgcccgtcca gcatcacgct gcccgcatcg gcggcaatga
    15601 gtccaacaat catgtagaag ctggtggttt tacccgcacc gttgggcccg agcaggccga
    15661 cgacttcccc gctttcgatt tcaagggaga agcttttaac gacttggcgt tttttgaaac
    15721 ttttttgcag gttttgaaca acaaggcggc tgacgtttgc gctcataaat atctcttcaa
    15781 tatcttcggt cggcaaatgc cgtccgaacc aggtttatgt ttcagacggc attttgggat
    15841 tattcggatt tttgcgtact cgaaggctgg ataacgacgc tgaccctgcc ggatttggaa
    15901 gcggattttg cgccggattt tgtgctgccg ctgatggtat agacttcggt tttggtgttg
    15961 tatgtaatca ccgcaccttc ggcgacatcg ccgccgcgct gtactctggc attaccggtt
    16021 aagactacgg tgctgcctgc agacgaataa gcaacgttgt ttgcctgtcc gcgcaccgtg
    16081 cctttgccgc cgtccaatgt ctggctgaag cggactggcg aaccttccgc cctcacggat
    16141 tcgccgcctt tgccgccgcg tgtaacattg acgcgggcgg cggaaatatt gagcgtaccc
    16201 tgtctgatga cgacgtttcc gctgaatgtg gtgctttggt tggcttgatc gagcgaacct
    16261 tggtcggcct caatctgaat aggctgcctg ctgtcgcttt gaagggcaaa agcgggggac
    16321 gccgaaaaaa atgctattaa aacaaatagc ttacatatct tttgtatcat aaatcgtggc
    16381 tttcacttta gatgagaagt tcaacatgcc tgttttgtgg tcgtaagtca tgccgcccgc
    16441 ctgaccgtgc gatgcaccat attggaaact gacaggcgta tcggtttggg catattgaga
    16501 ttcggtatcg acgtgcagct tttcggcttc aactttaccc gcctgccgtt tgccgtcggc
    16561 ggttttggtc agcacaacgt tgtttttaaa aagaacctgt ttgttttcgg tatggtaaac
    16621 ggcttcatcg ctgccgactt cgtacaacaa cctgccttct tggaagaaca cgagatgcgg
    16681 tgagtcgaaa tgaatgtcgc tgctttcggg aaactgtttc gcgcccttcg aactcaaatg
    16741 ttctttcaag tatccctgtt cgtcaaaccg cctgccatcc aatccgtcca ttgtgtattg
    16801 cggttcgtcg ggattgagcc tgacttcttc aatctcgact tcgctgatgc gtcccaacca
    16861 tgccgacagg ctgcccaagg caaccgccaa tatcaatggg aacgcaattc cgtaccgcca
    16921 tcttactttc atttgatgta ctcgttcaaa gccgcgccca aagtcccttg cgcctgcata
    16981 atcaggtcgc acacttcgcg caccgcgccc gcaccgccgg ggcgtttggc aatataggcg
    17041 gcgtgttgca gcgtaaacca atgcgcgtcg gggacggcaa ccggcaatcc gcagcgtacc
    17101 ataacgggca aatcgaccac gtcgtcgccg acaaaggcac actcggcttc ttccacgccg
    17161 acctgagcgc gcagctcttc atacgcggcg cgtttgtccg aaatgccttt gaagtagtaa
    17221 tttatgccca actgtttgac gcggatgccg acggagggcg cgtcccgacc tgtgataatc
    17281 gcagtctgca cgccgcttgc ctgaagcatt ttcagaccgt gtccgtccag tgtgtgaaac
    17341 gatttgattt cttcgccgtt atcgcggata aagatgcgcc cgtcggtcaa aacgccgtcc
    17401 acatccagga tcaacagttt gattttggcg gcgcgcgcct gtaattcggg agaaattgcc
    17461 tgcatgggat ttccttgttt tcagacggca tatcttacca caaatgccgt ctgaaacggc
    17521 tgcaacgcct
//
LOCUS       DAXIDM010000038        16867 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000038 DAXIDM010000000
VERSION     DAXIDM010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16867
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.038"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(148..342)
                     /locus_tag="ACFOAE_001041"
     CDS             complement(148..342)
                     /locus_tag="ACFOAE_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HFC6884543.1"
                     /translation="MKHKLASWWKTIKLTANLMAGVPDYENYVAQQRKHNPNAPVMTK
                     LQFQDYCRKRRCGANGGRCC"
     gene            complement(332..2413)
                     /locus_tag="ACFOAE_001042"
     CDS             complement(332..2413)
                     /locus_tag="ACFOAE_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009267 - cellular response to starvation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation CstA family protein"
                     /protein_id="HFC6884544.1"
                     /translation="MKSLKTFLIWGIVVLVGLASFTTLALSRGEQVSAVWMVTAAISV
                     YCIAYRFYSLYIANRVMRLDPNRLTPAERHNDGLDYVPTHKGVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGTLWIIFGVVFAGAVQDMMVLFVSMRRDGKSLGDIVKQELGTVPG
                     VIASIGILMIMVIIMAVLALIVVKALVHSPWGTFTIAATMPIALFMGIYTRYIRPGKI
                     GEISIVGFILLMLAVIYGEDVAKSSIGHWFDLDGIQLTWAIMIYGFVASVLPVWLLLT
                     PRDYLSTFLKIGTIAALALGIVIVNPALQMPAVTHFIDGSGPVFSGALFPFLFITIAC
                     GAVSGFHALISSGTTPKMLENETHVRMIGYGGMLMESFVAIMALAAAASLDPGVYFAM
                     NSPAALIGTDANTAAEVITTKLQFPVDAATLLHTAKEVGENTILSRAGGAPTLAVGMA
                     HIMSRLIPGEAMMAFWYHFALLFEALFILTAVDAGTRVARFMIQDLGSIFYKPFGNTD
                     SIPANLIATFFAVALWGYFLYTGVTDPLGGINSLWPLFGIANQMLAGVALIMCAVVLI
                     KMKRDRYVWVVLVPAVGVLFVTCYAGLQKLFHSDPRISFLAHAGKYSDALAKNEVLAP
                     AKDIGEMAQIIFNDKINAGLTILFLSVVVIVAAYGLRTALKARKVGWPTAKEIPAVYR
                     DSKQPEAQSEA"
     gene            2931..3311
                     /locus_tag="ACFOAE_001043"
     CDS             2931..3311
                     /locus_tag="ACFOAE_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MliC family protein"
                     /protein_id="HFC6884545.1"
                     /translation="MNIRFFALTVPVLSLAACAVPETYDGGGRGHMPPVQNQARPADF
                     RAFSCENGLSVRVRRLDGGRIALRLDGRRAVLSSDVAASGERYTAEHGLFGNGTEWHQ
                     KGGEAFFGFTDAYGNSVETSCRAR"
     gene            3375..3509
                     /locus_tag="ACFOAE_001044"
     CDS             3375..3509
                     /locus_tag="ACFOAE_001044"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884546.1"
                     /translation="MQFGLRQGFGYLIPSVTSGIAKFVGNGRCDLVGVSAELLRYFPL
                     "
     gene            complement(3595..4227)
                     /locus_tag="ACFOAE_001045"
     CDS             complement(3595..4227)
                     /locus_tag="ACFOAE_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884547.1"
                     /translation="MEKIEKFKSELLDNIFEYIQCISIFVHKKKIYYLIDYKENFILN
                     MKLDLDFDFKNGNITLEQYQDEINSCYYRNGIWQLTKDNFESYLQSDSVIVLKKDELK
                     ELMFQGFTSAEAVRLYSVVENKLSYNDPISDSGRQSDFLKINQISSRLPLFYVNFDTE
                     VYLHMDWDRCHEDYVYDGWFSKAMDFGYLIPDEFCYWKIEGRDYWKFGQL"
     gene            complement(4385..4876)
                     /locus_tag="ACFOAE_001046"
     CDS             complement(4385..4876)
                     /locus_tag="ACFOAE_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contact-dependent growth inhibition system
                     immunity protein"
                     /protein_id="HFC6884548.1"
                     /translation="MIFKQNQNYWAVFYTNEEALIVQTCSGLGLTAIDHLYPPHILPL
                     DTDNETLGTTVLQALANSRTLDNEAERIDFLKQENFKPRYEDWVAKLCGNLGYKTKRA
                     LFKNMMSVDIWLHNGCLKISPSRHVKLEAWDAIDADDVILSLDNSHEEIGAGLKLALS
                     RCR"
     gene            5013..5177
                     /locus_tag="ACFOAE_001047"
     CDS             5013..5177
                     /locus_tag="ACFOAE_001047"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884549.1"
                     /translation="MYKKVFFLNDRDCARAIFRHRPDVALPDRMLQTASEGFAVLEYE
                     DDNVREIDGI"
     gene            5210..6643
                     /locus_tag="ACFOAE_001048"
     CDS             5210..6643
                     /locus_tag="ACFOAE_001048"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFC6884550.1"
                     /translation="MNEYYQLIKHPDISLSPISDGIGVDNPATGEILAYVRKTDSDKL
                     KNLIQKAAAAQKLWAAKTALERADVLWRWYFQIKENKEALARLMTMEQGKSLTEARGE
                     IDYAASFVRWFAEEARRIDGDVLTSVKASQKLVVLKQPVGVTAAITPWNFPSAMIARK
                     AAPALAVGCAMIVKPASLTPLSAYALVVLAYEAGVPQDLLPVVSGRASEIGREFATNP
                     IIRKISFTGSTEVGAKIFADSAADIKKLSLELGGNAPFIVFDDADLDKAVEGALASKF
                     RNSGQTCVCTNRVYAQSAIYDEFCRKLSEKAAALKLGNGLEDGVNQGPLIEEKAVEKV
                     EQHIADALAKGASCLTGGKRSALGGTFFEPTVLSGVTAQMAVAREETFGPLCPVFRFE
                     TEAEVIEAANNTEYGLAAYLFTADTARQWRVGEALEYGMVGINTGLISNEAAPFGGVK
                     RSGLGREGSKYGADEYLELKYLCMDVG"
     gene            6753..7541
                     /locus_tag="ACFOAE_001049"
     CDS             6753..7541
                     /locus_tag="ACFOAE_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimb protein"
                     /protein_id="HFC6884551.1"
                     /translation="MMENGKTVPRWRFALKSAGWHLLISLSVAGLAALLVFKVWYPYP
                     YAELTGGLSLYQLVVAVDIVCGPLLTLILASPKKKTKARMVDFSMVGIIQLAALVYGL
                     HSVSLARPVIEAFEKDRINIVTAAEVAVEDLHKAPEGLQSLSWFGIRRIALKEPEDAD
                     EKNKTLDLSLKGIEPSMRPDRWLPYSDKEAEKIRKHLKPLKVLADARKTTVADILKQA
                     GLAEGEELYYLPFTSSRQKEWIVITDKEGNTKGYAPIDGFIITP"
     gene            7909..9465
                     /locus_tag="ACFOAE_001050"
     CDS             7909..9465
                     /locus_tag="ACFOAE_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter associated domain-containing
                     protein"
                     /protein_id="HFC6884552.1"
                     /translation="MDFSWLAEPHTWIGFATLLVLEVVLGIDNLVFVAILANKVQPAR
                     RDRARIIGLGLAVVIRIIMLAFMAHIITLTEPLFQIGGLAVSGKDMIMLAGGIFLLYK
                     ATTELHERLEGHNRFTVADSQKKHAPFWGVVAQILILDAVFSIDSVITAVAMVDHIVV
                     AMGAVVVAMAVMISASKLLTEFVDRHPTVVMLCLGFLLMIGFSLIAEAFHFHIPKGYL
                     YAAIGFSILIELFNQISQRNSRKNDYIGSSWRKRTAENVLGMMGIRESVLADAGGESG
                     DDAHFEENEKSMIRSVLTLAERPIMGVMIPRRDIERLDISQSREEQCAQLQNTPYSRL
                     LVVGKAGVDEPLGYINKKDLLSQLLETGGLDIQTALRQPLVLPDSTTALGAIELFRQS
                     SADYALVVDEFGAVLGMVTMKDLLETIAGEFPEEFEREEEPAVQGNPDESLTVEGALE
                     YVELASQLNLPQQEEDADFHTVAGLIMEELQTIPDVGDFADFHGWRFEVVEKEGQRIE
                     RVKITKLPEE"
     gene            9482..10228
                     /gene="surE"
                     /locus_tag="ACFOAE_001051"
     CDS             9482..10228
                     /gene="surE"
                     /locus_tag="ACFOAE_001051"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008252 - nucleotidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HFC6884553.1"
                     /translation="MNVLISNDDGYLSEGIAVLARVTAEFANVRVVAPERDRSGVSNS
                     LTLERPLQLKQAQNGFYYVNGTPTDCIHIGQSVFSDFQADFVFSGINRGANMGDDTLY
                     SGTVAAATEAYLMGIPAVAFSLNDASGRYWATAEQALWTLLAHFFKNPPQSPILWNIN
                     IPAVEPEDVRGIKIARLGRRHHGQNVIPARNPRGEQIYWIGPVGEVSDREEGTDFGEC
                     GAGFITVTPLQIDLTAYPDMAETAAFWHAD"
     gene            10484..11731
                     /locus_tag="ACFOAE_001052"
     CDS             10484..11731
                     /locus_tag="ACFOAE_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HFC6884554.1"
                     /translation="MLKQTTLLAACASFAALLGGCATQQPAPVIAGNSGMQDAPSSAV
                     YNNPYGATPYSPAPAGDAPYVPPVQSAPVYTPPAYVPPSAPAVSGTYVPSYAPVDINA
                     ATHTIVRGDTVYNISKRYHISQDDFRAWNGMTDNTLSIGQIVKVKPAGYAAPKTAAVE
                     SRPAVPAAAQPLVQSAPVDINAATHTIVRGDTVYNISKRYHISQDDFRAWNGMTDNML
                     SIGQIVKVKPAGYAAPKTSAVESRPAVPAAVQTPVKPAAQPPVQSAPQPAAPAAENKA
                     VPAPAPQSPAASPSGTRSVGGIVWQRPTQGKVVADFGGNNKGVDIAGNAGQPVLAAAD
                     GKVVYAGSGLRGYGNLVIIQHNSSFLTAYGHNQKLLVGEGQQVKRGQQVALMGNTDAS
                     RTQLHFEVRQNGKPVNPNSYIAF"
     gene            complement(12092..12574)
                     /locus_tag="ACFOAE_001053"
     CDS             complement(12092..12574)
                     /locus_tag="ACFOAE_001053"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFC6884555.1"
                     /translation="MTQQRQLPSHELIMSELMMPDTANFSGNVHGGELLLLLDQVAYS
                     CASRYSGNYCVTLSVDKVLFKEPIHIGDLVTFYAAVNYTGHTSMEIGIRVEAQNIRTG
                     EIRHTNSCYFTMVAVKGGKPVPVPPLEILTDRQRCRYEKAKKRRDISLQASEDMSCGC
                     "
     gene            complement(12727..12888)
                     /locus_tag="ACFOAE_001054"
     CDS             complement(12727..12888)
                     /locus_tag="ACFOAE_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884556.1"
                     /translation="MSGQPEKHHTSPIEDERKNPVYRMGQAVAGFMLVVWAGVLALVF
                     FLVFRFWLS"
     gene            complement(12962..13423)
                     /gene="recX"
                     /locus_tag="ACFOAE_001055"
     CDS             complement(12962..13423)
                     /gene="recX"
                     /locus_tag="ACFOAE_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFC6884557.1"
                     /translation="MKPQKSLRARAMDILSRQELSRIGLKRKLAPHAESEEELENVLN
                     EFAERNWQSDLRYAEAYIRSKSRKHGSLRLKQALAQQGIDEETSRNLLPDRSSEKQAA
                     IAVLRKKFKHPAADLKEKQKQARFLAYRGFDADTVQTALKHAWDENWEDGC"
     gene            complement(13491..14198)
                     /locus_tag="ACFOAE_001056"
     CDS             complement(13491..14198)
                     /locus_tag="ACFOAE_001056"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008967 - phosphoglycolate phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HFC6884558.1"
                     /translation="MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPA
                     KVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETE
                     AGLALLKSLGIPLAVITNKNEILAAELLKQLGLADYFSLILGGDSLPEKKPSPLPLRH
                     AAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIG
                     SLPEIYENLQPQKNKEE"
     gene            14605..15870
                     /locus_tag="ACFOAE_001057"
     CDS             14605..15870
                     /locus_tag="ACFOAE_001057"
                     /EC_number="1.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HFC6884559.1"
                     /translation="MSDAVAKETLNPFEIARKQVKTACDRLKTDPAVYEILKSPTRVL
                     EVNFPVKLDDGTVKTFTGYRSQHNNAVGPYKGGVRFHPGVNLDEVKALSIWMTIKCCV
                     AGIPYGGGKGGVTLDPRDYSEAELERIARAYSEAISPLIGEKIDIPAPDVNTNGKIMS
                     WMVDAYENVVKHSAPGVFTGKPVEFGGSLARTEATGYGVNLAAVQALEKLGKDVKGAT
                     YAIQGFGNVGYHTGYYAHQSGAKVVAVSTVDVAIYNENGLDMEALFKEFQEKGFITNE
                     AGYGKEITNAELLALDVDVLAPCALENQLTSENAGKVRAKIVVEGANGPTTPEADVIL
                     RQNGVLVVPDILANCGGVVVSYFEWVQNLQGYYWEFDEVQEKETVVLRRAFRDIWNLA
                     QEYDVDLRTASYMMSIRRVEKAMKLRGWY"
     gene            complement(15928..16734)
                     /locus_tag="ACFOAE_001058"
     CDS             complement(15928..16734)
                     /locus_tag="ACFOAE_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HFC6884560.1"
                     /translation="MKKTLTLLAVSALFATSAHAHRVWVETAHTHGGEYLKADLGYGE
                     FPELEPIAKDRLHIFSKPMQLVTEKGKENMIQRGTYNYQYRSNRPVKDGSYLVIAEYQ
                     PTFWSKNKAGWKQAGIKEMPDASYCEQTRMFGKNIVNVGHESADTAIITKPVGQNLEI
                     VPLDNPANIHVGERFKVRVLFRGEPLPNATVTATFDGFDTSDRSKTHKTEAQAFSDST
                     DDKGEVDIIPLRQGFWKANVEHKADFPDQSVCQKQANYSTLTFQIGHSHH"
BASE COUNT         3909 a         4156 c         4669 g         4133 t
ORIGIN      
        1 tctaaggtgc tgaagcaccg agtgaatcgg tttcgtacta tttgtactgt ctgcggcttc
       61 gtcgccttgt cctgattttt gttaatccac tatattataa aaattccgtc tgaagcggcg
      121 ttcagacgga atttgtttca agcaggctta acagcagcgt ccgccgtttg cgccgcagcg
      181 gcgtttgcgg caatagtctt gaaactgcag cttggtcatc acgggggcgt tgggattatg
      241 tttgcgctgc tgtgcaacgt agttttcata atcgggcacg cctgccatca agtttgccgt
      301 cagcttgatg gttttccacc aagacgcgag cttatgcttc actttgtgcc tccggctgtt
      361 tgctgtcgcg gtacaccgcc gggatttctt tggcggtcgg ccagccgact ttgcgtgctt
      421 tgagggcggt acgcaaaccg tacgcggcga caatcacgac aaccgacaag aagaggatgg
      481 tcagaccggc attaatcttg tcgttgaaga tgatttgcgc catttcgccg atgtctttgg
      541 caggcgcaag gacttcgttt ttagccaatg cgtcgctgta tttgccggcg tgggcaagga
      601 agctgatgcg cgggtcgctg tggaacagtt tttgcaggcc ggcgtagcag gttacgaaca
      661 gtacgccgac ggcgggaacg agtaccaccc aaacataacg gtcgcgtttc atcttaatca
      721 gcaccacggc gcacataatc aaggccacgc ctgccagcat ttggttggcg atgccgaaca
      781 aaggccagag cgagttgatg ccgcccagcg ggtcggttac gccggtgtag aggaagtagc
      841 cccacaatgc cacggcgaag aaggtcgcaa tcaggttggc ggggatggag tcggtgttgc
      901 cgaaaggttt gtagaagatg ctgcccaagt cttgaatcat aaaacgtgcg acgcgcgtac
      961 cggcatcgac ggcggtcagg atgaacaagg cttcaaacaa tagggcgaag tgataccaga
     1021 acgccatcat cgcctcgccc ggaatcaggc ggctcataat gtgcgccata ccgactgcga
     1081 gggttggcgc accgcctgca cgggaaagga tggtgttttc gcccacttcc ttagcggtat
     1141 gcaacagggt tgccgcatcg acagggaatt gcagcttggt ggtaatcact tcggcggcgg
     1201 tgttggcatc cgtaccgatc agggcggcag ggctgttcat ggcgaagtac acgccgggat
     1261 caagcgatgc ggcggcggca agcgccataa tggctacgaa actttccatc aacataccgc
     1321 cgtaaccaat catacggacg tgggtttcgt tttccagcat tttcggcgtg gtgccggagg
     1381 aaatcagcgc gtggaagccc gaaaccgcac cgcaggcgat ggtaatgaac aagaacggga
     1441 acaatgcgcc tgagaatacc ggacccgaac cgtcgataaa gtgggtaacc gcaggcattt
     1501 gcaaagcggg attgacgatg acgataccca aagccaaggc cgcaatcgta ccgattttca
     1561 ggaaggtaga gagatagtcg cgcggagtga gcagcaacca tacgggcaat acggaggcga
     1621 caaagccgta aatcataatc gcccaagtga gctggatgcc gtcaaggtcg aaccaatgtc
     1681 cgatggaact tttcgccaca tcttcgccgt aaattaccgc cagcatcagc aaaataaagc
     1741 cgacgatgga aatctcgccg attttgcccg gacggatata gcgcgtgtaa atacccataa
     1801 acagggcaat cggcatagtg gcggcgatgg tgaacgtacc ccaagggctg tgaaccaatg
     1861 cttttacgac aatcaacgcc aacaccgcca taatgatgac cataatcatc aaaataccga
     1921 tggaggcaat cacgccgggg acagtgccga gttcctgttt cacaatatcg cccaaagact
     1981 taccgtcgcg gcgcatagag acgaacaaga ccatcatatc ctgtaccgcg ccggcaaaca
     2041 ccacgccgaa gataatccac aaagtaccgg gcaggtaacc catttgcgcc gccaaaaccg
     2101 ggccgaccaa agggcccgcg cccgcaatcg cggcaaagtg gtgtccgaac aatacgccct
     2161 tgtgcgtcgg aacgtagtcc aagccgtcgt tgtggcgttc tgccggagtc aggcggttag
     2221 gatcgagccg cattacgcgg ttggcgatgt agaggctgta aaaacggtag gcgatgcagt
     2281 aaacggatat ggcggcggtg accatccata ccgcgctgac ctgttcgcct cggctgaggg
     2341 ccagagtggt aaaggatgct aagccgacca gtaccactat gccccaaatg aggaaggttt
     2401 tgagtgattt catcgaataa atccttatct cacactgtcg gaatatgcct gaacggcggg
     2461 aaacggccga accatctgcc ggcacgggca caaaccggag tctgaatgat tgacgaagta
     2521 tgaaacagtg cgcttgtcgg gatttgtgcc ttatgcccgc atcaaacagt gcagggatgc
     2581 gggcgcacaa aacgttaaac gccgaatagg attttaacgc aaattagcac actgatagcg
     2641 gtttttactt ggaatttgga aaaaatttac attccttcgg gcggacaggc gggtttggac
     2701 ggcatcgtca ggcaaaaggc ggcgccggaa gacgggtaaa gaaggggcgc gcaatccgga
     2761 ttattgattc atcgtgtttc cttttcggtt gaacctcagc cctttggggc ggtagaatca
     2821 gactttattt tgggggcgca accccttccg aatcaggacg gcacataggg cggtgcttta
     2881 tgtgtcgtcc tgtgtgttga aacatatttt ctttttattt gggagctttt atgaatatca
     2941 ggtttttcgc actgaccgtg ccggttttgt ctctggcggc ctgtgccgtg ccagagacgt
     3001 atgatggcgg cggacgcggg catatgccgc ccgttcaaaa ccaagcccgc ccggcagatt
     3061 ttcgggcatt ttcctgcgag aacggtttgt ctgtgcgcgt ccgccgtttg gacggcggca
     3121 gaatcgcgtt gcggttggac ggcaggcgtg ccgtcctctc ttccgacgtt gccgcatccg
     3181 gcgaacgcta taccgccgaa cacggtttgt tcggaaacgg aaccgagtgg caccagaaag
     3241 gcggcgaagc ctttttcggc tttaccgatg cctacggcaa ttcggtcgaa acttcctgcc
     3301 gcgcccgtta aacggggcag cctgtttgaa ccgccgtccg gatttttcgg gcggtttttt
     3361 atgtcggatt tgttttgcag ttcggcctcc ggcagggttt tggctacctg ataccgtccg
     3421 taacttcggg tattgccaag tttgtcggca acggccgctg cgacttggtc ggcgtttctg
     3481 ccgaactcct gcgttacttc cctttgtagg ttgatctctt tggcaaccgc gtctttgtcg
     3541 aagctgtttt tcagacgacc ttttgaattc atacaagcta tggcttgctt atctttataa
     3601 ttgtccaaat ttccaataat cccgtccttc aattttccaa taacaaaatt cgtccggtat
     3661 taaataccca aaatccatcg cctttgaaaa ccagccgtca taaacataat cttcatgaca
     3721 tctgtcccaa tccatatgta agtatacttc agtgtcaaaa ttgacataga ataaaggcag
     3781 cctcgaggaa atctgattga tttttaagaa atcactttgc cggccggagt ctgagatagg
     3841 atcattgtac gacagcttgt tctcgacaac ggaatataac cttaccgctt cagcagaagt
     3901 aaatccctga aacatcagtt ccttcaattc atcctttttt aatacaatga ctgaatccga
     3961 ttgaagatag ctttcaaaat tgtccttagt taactgccag ataccattac ggtaataaca
     4021 actatttatt tcatcctgat attgttctaa cgtaatattc ccgtttttaa aatcaaaatc
     4081 taaatccaac ttcatgttta atatgaaatt ttccttataa tcaatcaaat aatatatctt
     4141 tttcttgtgg acaaaaatag atatgcattg aatgtactca aaaatgttat ccaataattc
     4201 agatttaaat ttctcaatct tttccatatt tgccaaattc cttaataact ttatcttcag
     4261 caagtcgtag cccgcattaa atctgcagct aaggtgtgcg cggtacgcac gcccgtgagt
     4321 ttgagtctaa taaaaaggtt gtctgaaaca tttttccggc tttcagacga ccttttgtca
     4381 aatattatcg gcagcggctc aatgccaact ttaaacctgc tccgatttct tcatggctgt
     4441 tatccaatga taaaattaca tcgtctgcat caatggcatc ccacgcttcc agcttgacat
     4501 ggcggctcgg gctgattttc aggcagccgt tgtgcagcca aatatccacg ctcatcatgt
     4561 ttttaaatag ggcgcgtttg gttttatagc ccaagttccc gcatagcttg gcaacccaat
     4621 cctcatagcg tggtttaaaa ttttcctgtt ttaaaaaatc aatacgttca gcttcgttgt
     4681 ctaacgtcct gctgtttgcc aacgcttgca agaccgttgt gcctaaagtt tcattgtcgg
     4741 tatccaatgg caggatatga gggggatata ggtggtctat tgccgttaat cccaaacctg
     4801 aacatgtttg aacaatcaga gcttcttcat tcgtataaaa aactgcccaa taattttgat
     4861 tctgtttaaa aatcattatt ttatctccgt aattttgact gtaatgtttt gacttttgcc
     4921 atactctacc acacgttgca actgcaatct ttgctcctta tatattgcac cccatcaaag
     4981 ggctgcatta cttttctttc taaagattac cattgtataa aaaagtattt ttcttaaacg
     5041 acagggattg cgcccgcgcc atattcagac accgcccaga tgttgcgctg cccgatcgga
     5101 tgcttcagac ggcatcggaa gggtttgcag ttttggaata tgaagatgat aatgtccgcg
     5161 agattgacgg catttgaaag cggttattcc gcataccgga ggacacgaaa tgaacgaata
     5221 ttaccaatta atcaagcatc ccgatatttc cctttccccg atttcagacg gcatcggggt
     5281 cgacaatccg gcaacgggcg aaattttggc gtatgtccgc aagacggatt cggacaagct
     5341 gaaaaacctg attcaaaaag cagctgcagc acaaaaatta tgggcggcaa aaactgcgtt
     5401 ggaacgcgcc gatgtgttgt ggcgttggta ttttcagatt aaagaaaaca aagaagcatt
     5461 agcgcgcctg atgacgatgg agcagggcaa aagcctgacc gaggcgcgtg gcgaaatcga
     5521 ttatgcggct tcgtttgtgc gctggtttgc cgaagaggcg cggcggattg acggcgatgt
     5581 gttaacgagt gtgaaagcgt cgcaaaaact ggttgtgttg aaacagcctg tcggtgttac
     5641 cgccgcgatt acgccgtgga acttcccgtc tgcgatgatt gcgcgcaagg ctgcgcctgc
     5701 tttggcggtg ggctgcgcga tgatcgtcaa acccgcatcg ctcacgcctt tgagtgcgta
     5761 tgcgttggtc gtgctggctt atgaagcggg cgtaccacag gatttgttgc ccgtcgtcag
     5821 cggtcgcgca tcggaaatcg gccgtgaatt tgccacgaac ccgattatcc gcaaaatcag
     5881 cttcaccggc tcgaccgaag tcggcgcaaa aatttttgcc gacagcgcgg cggacattaa
     5941 aaaactcagt ttggagctgg gcggcaacgc gccgtttatc gtgtttgacg atgccgattt
     6001 ggacaaagcc gtcgaaggcg cgctcgccag caagttccgt aacagcggtc agacctgcgt
     6061 ctgcaccaac cgcgtttacg ctcaatccgc catttacgac gaattttgcc gcaaattgag
     6121 tgaaaaagca gccgcgctca aattgggcaa cggcttggag gatggtgtga accaagggcc
     6181 gctgattgag gaaaaagcgg tggagaaagt cgagcagcac atcgccgacg cgcttgctaa
     6241 aggtgcaagc tgcctgaccg gcggcaaacg cagcgcgttg ggcggaacgt ttttcgaacc
     6301 gactgtttta agcggcgtaa cggcgcaaat ggcggtggca cgcgaagaaa ccttcgggcc
     6361 gttgtgtccg gtattccgtt ttgaaaccga agccgaggtc atcgaggctg cgaacaatac
     6421 ggaatacggt ttggcagctt accttttcac cgccgacacc gcccgccaat ggcgcgtcgg
     6481 cgaagccttg gaatacggta tggtcggcat caatacgggc ttaatcagca atgaagcggc
     6541 accgttcggc ggcgtgaaac gtagcggttt gggacgtgaa ggcagcaaat acggtgcgga
     6601 cgaatatctg gaattgaaat atctgtgtat ggatgtcggg tgacggatgc cgtctgaacg
     6661 gcagggtttc agacggtgcc gcattttaag cagtctctat ctgttgtaca atgcgccctg
     6721 tttttacggt tatttttgat gtgaattaag atatgatgga aaacggaaaa acagtcccga
     6781 gatggcgttt tgccttgaaa agtgcgggtt ggcatctctt aatcagcctg tcggttgcag
     6841 ggctggcggc attgctggtt tttaaggttt ggtatcctta tccttatgcc gagctgacgg
     6901 gagggctgtc gctttatcag ctggtggtgg ctgtcgatat tgtatgtggt ccgctgctga
     6961 ctttaatttt ggcaagcccg aagaaaaaga caaaggcacg catggtcgat ttttccatgg
     7021 tcggcatcat ccagctggcg gctttggtgt acggtctgca cagcgtttcg ctggcgcgcc
     7081 ctgtgataga ggcgtttgaa aaagacagga ttaatattgt aaccgccgcc gaagtggcgg
     7141 ttgaagacct gcacaaagcg ccggaagggc tgcaaagcct gtcgtggttc ggcatccgcc
     7201 gcattgcatt gaaagaacct gaggatgcgg atgagaagaa caagacgctg gatttgtccc
     7261 tgaaaggtat cgagccgagt atgcgtcccg accggtggct gccgtattcc gacaaggaag
     7321 cagaaaaaat ccgcaaacat ctgaaaccgc tgaaagtctt ggcggatgcg agaaaaacga
     7381 cggttgcgga cattctgaaa caggcaggtc tcgccgaagg ggaggagctg tattacctgc
     7441 cgtttaccag cagcaggcag aaagagtgga tagtcattac cgataaagag ggcaacacca
     7501 aaggctacgc gccgatagac ggcttcatca tcacccctta agcgttggga ctccgtccgc
     7561 actcgaacat ccgttcttcg cggcggtaga atcagactgt atttgagagg ggcgcaaccc
     7621 ctcaatcagg gcaacacata ggggaaggct ttatgtgccg tccgtgtgtt gaaacatttc
     7681 aaaataagct catgccgtcc gaacatcctt tcagacggta tggcattttg ccattgcccc
     7741 gataagctgt taaactattt aaattatttc gaccgaaggt acacgcacat gcaagacccc
     7801 gagcagagca gcaagcccgc ccgccgtttt ttgtgcgtac cgtctgttca ggcagcttga
     7861 gcgcttcagg ctgccttttc gcgtttgaac ttgaggaata cgaaaatcat ggatttcagt
     7921 tggttggcag aaccgcatac ctggataggt tttgccacgc ttttggtgtt ggaagtcgta
     7981 ttggggatag acaatcttgt ctttgtggcg attttggcaa acaaggtcca gcccgcacgg
     8041 cgcgaccgcg cacggattat cgggctgggg ctggcagtcg tcatccgcat cattatgctt
     8101 gcttttatgg cgcacatcat cacgctgacc gagccgctgt tccaaatcgg cggcctcgcc
     8161 gtttccggca aggacatgat tatgctcgcg ggcggtattt tcctgcttta caaagccacc
     8221 accgaactgc acgaacgcct cgaagggcac aaccggttta ccgttgccga cagccagaaa
     8281 aaacacgcgc cgttttgggg cgtggtcgcg caaatcctga tactggatgc tgtgttttcc
     8341 atcgattcgg tcatcaccgc cgtagcgatg gtcgatcata tcgtcgtggc gatgggtgcg
     8401 gtcgtcgtcg cgatggctgt aatgatttct gccagcaaac tcttgaccga atttgtcgac
     8461 agacacccta ccgtcgtgat gctctgcctt ggttttttgt tgatgatcgg tttcagcctg
     8521 attgccgaag ccttccattt ccacattccc aaaggctacc tctacgccgc catcggcttc
     8581 tcgattttaa tcgaactgtt taaccagatt tcccagcgca acagccgcaa aaacgactac
     8641 atcggcagct cgtggcgcaa gcgcaccgcc gaaaacgttt tgggtatgat gggcatacgc
     8701 gaaagcgtgc ttgccgatgc gggcggcgaa tccggggacg acgcgcattt tgaagaaaac
     8761 gaaaaatcga tgatacgcag cgtgctgacg cttgccgaac gcccgattat gggggtgatg
     8821 atcccacgcc gcgacatcga acggctggac atttcccaaa gccgcgaaga acagtgtgcc
     8881 caactgcaaa acacgcctta cagccgcctg ctcgttgtcg gtaaggcggg cgtggacgaa
     8941 cctttgggct acatcaacaa aaaagacctg ctgtcccaac tgctggaaac aggcggtctc
     9001 gacattcaga cggcattgcg ccagccactc gtcctgcccg acagcaccac cgcgctgggc
     9061 gcaatcgaac tcttccgcca aagcagcgcg gattatgctt tggtggtgga cgagttcggc
     9121 gcggtattgg gcatggtaac catgaaagac ctgctcgaaa ccatcgcagg cgagttcccc
     9181 gaagaatttg agcgcgaaga agaaccagcc gttcagggga atcccgatga aagcctgacg
     9241 gtggaaggcg cgttggaata tgtggagctg gcatcccaac tcaatctgcc gcagcaggag
     9301 gaagatgccg atttccatac ggttgccggg ctgattatgg aagaattgca aaccatcccc
     9361 gatgtcggcg attttgccga tttccacggc tggcggtttg aagtggtcga aaaagaaggg
     9421 cagcgcatcg agcgggtcaa aatcaccaaa ttgcccgaag aataagcatt caggatagaa
     9481 aatgaacgtt ttgatttcca acgacgacgg ctacctctcc gaaggtattg ccgttttggc
     9541 gcgcgttacg gcggaatttg ccaacgtcag ggtggttgcg cccgaacgcg acaggagcgg
     9601 ggtcagcaat tcgctgacgc tggaacgccc tttgcagttg aaacaggcgc aaaacgggtt
     9661 ctactatgtc aacggcacgc cgaccgactg catccacatc gggcagtctg tattttcgga
     9721 ttttcaggcc gattttgtct tttcgggcat caaccggggc gcgaatatgg gggacgacac
     9781 gctttattcg gggacggttg cggcggcaac cgaagcctac cttatgggca tacccgctgt
     9841 ggcgttttcc ttaaacgacg cttccggacg ctattgggcg accgcagaac aggcactgtg
     9901 gacattgttg gcgcattttt tcaaaaaccc cccgcagtcc cctattttgt ggaacatcaa
     9961 tatccccgcc gtcgagccgg aagatgtgcg gggcattaaa atcgcccgtt tgggcaggag
    10021 gcatcacggt cagaacgtca tccccgcgcg caatccgcgc ggcgaacaga tttattggat
    10081 aggaccggtc ggcgaagttt ccgatcggga agagggaacg gatttcggtg aatgcggcgc
    10141 aggtttcatt accgtaacgc cgctgcaaat cgacctgacc gcctatccgg acatggcgga
    10201 aacagcggcg ttctggcatg cggactgacc gtttcatcaa atatagtgga ttaacaaaaa
    10261 ccagtacggc gttgcctcgc cttagctcaa agagaacgat tctctaaggt gctgaagcac
    10321 caagtgaatc ggttccgtac tatttgtact gtctgcggct tcgtcgcctt gtcctgattt
    10381 ttgttaatcc actataccgt cgggctttgc gcttgagaag aacgcgcatt tttattatga
    10441 tataccgcat tcaggctata tatcggaaca tgaaggttat cttatgttga aacaaacgac
    10501 acttttggcg gcttgcgcct cctttgccgc actgttgggc ggttgtgcta cccagcagcc
    10561 tgcccccgtc attgcaggca attcaggtat gcaggacgcg ccgtcttcgg cagtttacaa
    10621 caacccctat ggagcaacgc cgtacagccc ggctcctgcc ggcgatgcgc cttatgtgcc
    10681 gccggtgcaa agcgcgccgg tttatacgcc tcctgcttat gttccgccgt ctgcacctgc
    10741 cgtttcgggt acatacgttc cttcttacgc acccgtcgac atcaacgcgg cgacgcatac
    10801 tattgtgcgc ggcgacacgg tgtacaacat ttccaaacgc taccatatct ctcaagacga
    10861 tttccgtgcg tggaacggca tgaccgacaa tacgttgagc atcggtcaga ttgttaaagt
    10921 caaaccggca ggatatgccg caccgaaaac cgcagccgta gaaagcaggc ccgccgtacc
    10981 ggctgccgcg caaccgctcg tacagtccgc acccgtcgac atcaacgcgg cgacgcatac
    11041 tattgtgcgc ggcgacacgg tgtacaacat ttccaaacgc taccatatct ctcaagacga
    11101 tttccgtgcg tggaacggca tgaccgacaa tatgttgagc atcggtcaga ttgttaaagt
    11161 caaaccggca ggatatgccg caccgaaaac ctcagccgta gaaagcaggc ccgccgtacc
    11221 ggctgccgtg caaacccctg tgaaacccgc cgcgcaaccg cctgtgcagt ccgcgccgca
    11281 acctgccgcg cccgctgcgg aaaataaagc ggttcccgcg cccgccccgc aatctcctgc
    11341 cgcttcgcct tccggcacgc gttcggtcgg cggcattgtt tggcagcgtc cgacgcaagg
    11401 taaagtggtt gccgatttcg gcggcaacaa caagggtgtc gatattgccg gtaatgcggg
    11461 acagcccgtt ttggcggcgg ctgacggcaa agtggtttat gcaggttccg gtttgagggg
    11521 atacggcaat ctggtcatca tccagcataa ttcttccttc ctgaccgcat acgggcacaa
    11581 ccaaaaattg ctggtcggcg aaggccagca ggtcaaacgc gggcagcagg tcgctttgat
    11641 gggcaatacc gacgcttcca gaacgcagct tcatttcgag gtgcggcaaa acggcaaacc
    11701 ggttaatccg aacagctata tcgcgttctg actttctgcc tgaaatcaag ttggaaatgc
    11761 cgtctgaaag gttttcagac ggcatttttg tttttggcgg ctgtgttttc aaattattcg
    11821 gaagggatgg ggcatataaa tttgtttgac tgtgtttggg tatagtggat taacaaaaat
    11881 caggacaagg cgacgaagcc gcagacagta cagatagtac ggagccgatt cacttggtgc
    11941 ttcagcacct tagagaatcg ttctctttga gctaaggcga ggcaacgccg tactggtttg
    12001 aatttaatcc actatatttg cttgatttca tccgtttgca atggaaacgg atggcgcgat
    12061 gtgcctgtct ttcagacggc atagtccgcc gtcagcagcc gcaggacatg tcttcagagg
    12121 cttgcaggct gatgtctctg cgttttttgg ctttttcgta gcggcagcgt tggcggtcgg
    12181 tcaggatttc cagcggaggg acagggacgg gtttgccgcc tttgaccgca accatcgtga
    12241 agtagcagct gttggtatgg cggatttcgc cggtgcggat gttttgtgct tcgacacgga
    12301 tgccgatttc catcgaggtg tgtcccgtgt agttgacagc ggcgtaaaag gtaaccaaat
    12361 cgccgatgtg gatgggttct ttaaacagga ctttgtcaac cgacagggta acgcaataat
    12421 tgccgctgta acggctggcg caggaatagg cgacttggtc gagcaggagc aggagttcgc
    12481 cgccgtgtac gttgccgctg aaattggcgg tgtccggcat catcagttcg gacataatga
    12541 gttcgtggga aggcagttgg cgttgttgtg tcatagtgta cctgttttaa gaaagggtgt
    12601 tttgaaatgg gtgtgggaaa attttaggga atggggaagt ggaattcaag ctaaaaaaag
    12661 ctatggcggg atagtctgca gaaatgggcc gccgatgccg tctgaagcct tcagacggca
    12721 ttttgtttag gaaagccaaa aacggaagac caggaaaaac acgagtgcca atacgcctgc
    12781 ccaaacgacg agcatgaatc cggcaactgc ctgccccatg cggtaaaccg ggtttttgcg
    12841 ttcgtcttcg atgggggagg tgtggtgttt ttcgggttgt ccggacattt tgttctcaat
    12901 cggaaaagtt ggaaacgggc gtaaggttat gttgccgtgc aaaaagattc aagaaggaag
    12961 gtcagcagcc gtcttcccaa ttttcgtccc aagcgtgttt caatgccgtc tgaacggtat
    13021 cggcatcgaa tccgcgatag gcgaggaaac gcgcctgttt ttgtttttct ttaaggtcgg
    13081 cggcggggtg tttgaatttt ttacgcaaca cggctatggc ggcctgtttt tcgcttgagc
    13141 ggtcgggaag caggttgcgg ctggtttctt catctatgcc ctgttgcgcc aaagcctgtt
    13201 tcagcctcaa tgaaccgtgt ttgcggcttt tgctgcggat ataggcttcg gcatagcgca
    13261 aatccgactg ccagttgcgt tcggcaaatt cgtttaacac gttttccaac tcctcttcgc
    13321 tttcggcgtg cggtgcaagt ttgcgtttca gaccgatgcg gctgagttct tggcgcgaga
    13381 ggatgtccat cgcgcgggcg cgtagggatt tttgcggttt catggcggcg gtttcggcgt
    13441 ggggcaggtt tcagacggca tagcggcgca aaccggagcc gtccgaatgc ctactcttct
    13501 ttgtttttct gaggttgcag gttttcgtaa atttcgggca gcgagccgat aatccagtcg
    13561 gggcgggtcg catcgtcttg cgagagcagc gtcatatcgc cgtaaccgaa ggtaacgccg
    13621 acgctcaggc agccggcggc tttggcggcg atgatgtcgt tgcgcgagtc gccgaccata
    13681 accatgtttg caacatcgat acccaaaact tcggcggcat gccgcagcgg cagggggctg
    13741 ggttttttct cgggcaggct gtcgccgccg agtatcaggc tgaagtagtc ggcaagtccg
    13801 agctgtttca acagttcggc ggcaaggatt tcgtttttat tggtaatgac tgccagcggg
    13861 atgcccaaag atttgagcaa tgccagcccg gcttcggttt cgggataggg gcgggtgaag
    13921 acgctcaaat ggtcgcggta gtatttcata taggatacga aacctttttc ccacagttcg
    13981 gaatcggctt cgcggtcgcg gtcgttggtg aggacgcggt gaaccagttt gccgatgccg
    14041 tcgcccacat agctttcgac cacttttgca ggcagcggtt tcataccgag ttgttccaac
    14101 atcgcttctg cggcggcggc aaggtcgggg acggaatcgc acagtgtgcc gtccaaatcg
    14161 aaggcgacgg cttggacgtg ttcgatggct gcattcataa tctgatttcc tgtcgggttg
    14221 aaagggttta ttttaacatc gtttgcacag ggcttctaat gtatagattg ttaacaatcg
    14281 caacaggttt tgcaggcggt gttttcggat ttcggggcgg aatcgggcaa gggtttgaaa
    14341 tcccggcgat gttccaatta aatttttaaa aaataaaagg atgcctatat ctttatttaa
    14401 tttgacattt atttttcgga cgcgcgcgct gctttttcag gcggagtcca ggctgattcc
    14461 gtgcggcttg aaaaataaaa tcatatatag attaatcaaa tcgggcttat gccgactaca
    14521 cgctattaca ttttgtcggg aaattggtta tagtaatgag cgaaatgcac gcccctgaaa
    14581 atctttttgt gaaaaggaag caaaatgtct gatgccgttg caaaagaaac cctcaatccg
    14641 tttgaaatcg cgcgcaaaca ggtcaaaacc gcctgcgacc ggctgaaaac cgatccggcc
    14701 gtttatgaaa tcctgaagag tccgacccgc gtgttggaag tcaatttccc cgtcaaactc
    14761 gacgacggca cggtcaaaac cttcacgggc taccgttcgc aacacaacaa cgccgtcggc
    14821 ccctataaag gcggcgtgcg cttccatccc ggtgtgaatc tggacgaagt caaagccctg
    14881 tcgatttgga tgaccatcaa atgctgcgtg gccggcattc cttacggcgg cggcaaaggc
    14941 ggcgttacct tggatccgcg cgattattcc gaggcggaac tggaacgcat cgcccgcgct
    15001 tattccgaag caatttctcc gctgattggc gagaaaatcg atattcccgc ccccgatgtg
    15061 aataccaacg gcaaaattat gtcgtggatg gtggatgcct atgaaaacgt ggtgaaacat
    15121 tctgcaccgg gcgtatttac cggtaaaccg gttgagttcg gcggctcttt ggcgcgtacc
    15181 gaagccacgg gttacggcgt gaacctcgcc gccgtccaag ccttggaaaa actgggcaaa
    15241 gacgtgaagg gtgccactta cgccattcaa ggtttcggta atgtgggtta ccacacaggt
    15301 tattacgcgc atcaatccgg cgcgaaagtt gttgcggttt ctactgtcga tgttgccatt
    15361 tacaacgaaa acggtttgga tatggaagcc ctgttcaaag agttccaaga aaaaggcttc
    15421 atcaccaacg aagccggtta cggcaaggaa attaccaacg ccgaactttt ggctttggat
    15481 gtggacgtac tcgccccttg cgcgctggaa aatcaactga cttctgaaaa cgccggtaaa
    15541 gtccgcgcga aaatcgtggt cgaaggcgcg aacggcccga ctacgcccga agccgacgtt
    15601 atcctgcgtc aaaacggcgt attggtcgtg cctgatattc tggcgaactg cggcggcgtg
    15661 gtcgtttcct atttcgagtg ggtgcaaaac ctgcaaggct attattggga gtttgacgaa
    15721 gttcaagaga aagaaaccgt cgtcctgcgc cgagcgttcc gcgatatttg gaacttggct
    15781 caagaatacg atgtcgattt gcgaaccgcg tcttatatga tgagtatccg ccgtgttgaa
    15841 aaagcgatga aactgcgcgg ttggtattga tgtttgaaca aaaaatgccg tctgaagcct
    15901 tcagacggca tttttgtgcg ggcgggatta atggtgcgaa tggccgattt ggaaggttaa
    15961 agtcgagtag ttcgcctgtt tttggcacac gctttgatcg gggaagtcgg ctttgtgttc
    16021 gacattggct ttccagaagc cttggcgcaa ggggatgatg tccacttcgc ctttgtcgtc
    16081 tgtgctgtcg gagaaagcct gtgcttcggt tttgtgcgtt ttgctgcggt cgctggtgtc
    16141 gaagccgtca aaggtggcgg taacggtggc attgggcagc ggttcgccac ggaacagaac
    16201 gcggactttg aagcgttcgc ctacgtgaat gttggcggga ttgtccagcg ggacgatttc
    16261 caagttttgt ccgaccggtt tggtgatgat ggcggtgtcc gcgctttcgt gtccgacgtt
    16321 gacgatgttt ttgccgaaca tacgggtttg ttcgcaatag cttgcgtcag gcatttcttt
    16381 gatgcccgcc tgtttccagc ctgctttgtt ttttgaccag aaagtaggct gatattcggc
    16441 gatgacgagg taactgccgt ccttaacggg acggttgctt cggtactggt agttgtatgt
    16501 gccgcgttga atcatgtttt ccttgccttt ttcggtaacc agctgcatcg gtttgctgaa
    16561 gatgtgcagg cggtctttgg cgatgggttc gagttcggga aattcgccgt agcccaagtc
    16621 ggctttaagg tattcgccgc cgtgcgtgtg ggcggtttcg acccagacgc ggtgggcgtg
    16681 ggcggatgtg gcaaataggg cggaaacggc gagcagtgtc aatgttttct tcatggtgca
    16741 gcctttgtct cgtgtgggtt aaagattttg ttatgttata acaaaatagg tatcgtgtga
    16801 agacggattt gctgtctgaa aactgtcttt ttgtatagtg gattaacaaa aaccagtacg
    16861 gcgttgc
//
LOCUS       DAXIDM010000039        16719 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000039 DAXIDM010000000
VERSION     DAXIDM010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16719
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.039"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            50..1180
                     /locus_tag="ACFOAE_001059"
     CDS             50..1180
                     /locus_tag="ACFOAE_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HFC6884561.1"
                     /translation="MFTDENMTAKEELFAWLRHMNQNKGSDLFVTTHFPPAMKLDGKI
                     TRITDEPLTAEKCMEIAFSIMSAKQAEEFSSTNECNFAISLPDTSRFRVNAMIQRGAT
                     ALVFRAITSKIPKFESLNLPPVLKDVALKKRGLVIFVGGTGSGKSTSLASLIDYRNEN
                     SFGHIITIEDPIEFVHEHKNCIITQREVGVDTENWMAALKNTLRQAPDVILIGEIRDR
                     ETMDYAIAFAETGHLCMATLHANSTNQALDRIINFFPEERREQLLTDLSLNLQAFISQ
                     RLVPRDGGKGRVAAVEVLLNSPLISELIHNGNIHEIKEVMKKSTTLGMQTFDQHLYQL
                     YEKGEISLQDALKNADSAHDLRLAVQLRSRRAQSSSPDLELL"
     gene            1214..2191
                     /locus_tag="ACFOAE_001060"
     CDS             1214..2191
                     /locus_tag="ACFOAE_001060"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFC6884562.1"
                     /translation="MIYPWHNEQWRQIAEHWERRPNAWLFAGKKDTGKTTFARFAAKA
                     LLCETPAPGCKPCGECMSCHLFGQGSHPDFYEITPLSDEPENGRKLLQIKIDAVREII
                     DNVYLTSVRGGLRVILIHPAESMNVQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTI
                     KSRCRKMVLPAPSHEEALAYLRERGVAEPEERLAFHSGAPLFDEADGVRALRIKLLDI
                     LAEPRLLKILDYAALFDKEKLPLAVFVGWMQKWLVDLGLCLQHMKPVYYPAYEDRLLQ
                     TVSGFRPRNVFAAEDMLKQLAPYGFHTLNVKMQIEHLLINYLELKKENG"
     gene            2195..2545
                     /locus_tag="ACFOAE_001061"
     CDS             2195..2545
                     /locus_tag="ACFOAE_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0035438 - cyclic-di-GMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PilZ domain-containing protein"
                     /protein_id="HFC6884563.1"
                     /translation="MSDGQNIPAKMMSLQLKDMNLLYSSYMPFLEHGGLFVQTNDVFS
                     IGDDILLAVEILNFPKLFLPTKVAWINPARTSSKPKGVGLAFTKHENCLKVKDQIEVE
                     LGNTIGGSRPTFTM"
     gene            2550..3329
                     /locus_tag="ACFOAE_001062"
     CDS             2550..3329
                     /locus_tag="ACFOAE_001062"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFC6884564.1"
                     /translation="MHIIDSHCHLNFEGLKERLPEVLSNMEANGVGQALAISVSRESF
                     AEVSAIAEVYEHIYCTIGVHPDSKEAEEFSIAEMVAAAAHPKVVGIGETGLDYYWCKG
                     DLSWQHKRFADHIEAANQTGLPVIVHTRDAAADTLSILKECRVNSGVIHCFSEDIGFA
                     RAAMDLGLYISFSGIVTFKNAPLVQEAAKYVPDDRILVETDAPFLAPVPKRGRQNEPA
                     FVRHTAEHIAKLRNQTLEQVAAYTTENFYRLFKKVPDMRAV"
     gene            3355..3569
                     /locus_tag="ACFOAE_001063"
                     /pseudo
     CDS             3355..3569
                     /locus_tag="ACFOAE_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
     gene            3670..3981
                     /gene="grxD"
                     /locus_tag="ACFOAE_001064"
     CDS             3670..3981
                     /gene="grxD"
                     /locus_tag="ACFOAE_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Grx4 family monothiol glutaredoxin"
                     /protein_id="HFC6884565.1"
                     /translation="MASIHDQIKEVVTTHRVVLFMKGTKQFPQCGFSSRAVQILNAAG
                     CTDYVTVNVLENPEVRQGIKEYSDWPTIPQLYVNGEFVGGSDILMEMYEAGELQELLK
                     A"
     gene            4087..4713
                     /gene="upp"
                     /locus_tag="ACFOAE_001065"
     CDS             4087..4713
                     /gene="upp"
                     /locus_tag="ACFOAE_001065"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006223 - uracil salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFC6884566.1"
                     /translation="MNVNVINHPLVRHKLTLMREADCSTYKFRTLAIELARLMAYEAS
                     RDFEIEKYLIDGWCGQIEGDRIKGKTLTVVPILRAGLGMLDGVLDLIPTAKISVVGLQ
                     RDEETLKPVSYFEKFVDSMDERPALIIDPMLATGGSMVATIDLLKAKGCKNIKALVLV
                     AAPEGVKAVNDAHPDVTIYTAALDSHLNENGYIIPGLGDAGDKIFGTR"
     gene            4736..5056
                     /locus_tag="ACFOAE_001066"
     CDS             4736..5056
                     /locus_tag="ACFOAE_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2322 family protein"
                     /protein_id="HFC6884567.1"
                     /translation="MNFQDYLATFPSIDHLGGLDVQDADGKTVHHIPAVQGKLGSLKL
                     YNALAERFDGKLDKEAAEQGLIWFAEHVADARAHPGKHPNIDLLEKVVQSGETLLLKP
                     LAAQ"
     gene            5306..5728
                     /locus_tag="ACFOAE_001067"
     CDS             5306..5728
                     /locus_tag="ACFOAE_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein Gly1ORF1"
                     /protein_id="HFC6884568.1"
                     /translation="MKKTFLSAVLLLSAATQTVWADTVFSCKTDNNKYIEVQKINRNL
                     YEYSFGSAAKKEIAIRNSKADLLGRSDRWQGWGRGRWATMKFQNGEFMYTIWTGFDSV
                     THTESSGVVVERRGKEVARVGCTPQTAQANFNDADFSR"
     gene            5746..6507
                     /locus_tag="ACFOAE_001068"
     CDS             5746..6507
                     /locus_tag="ACFOAE_001068"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004852 - uroporphyrinogen-III synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006780 - uroporphyrinogen III biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HFC6884569.1"
                     /translation="METVKPIMLIVRPSGRAKDDVETCRRAGWQAEVLSPIEIEADAA
                     GLELLSEQYARADAVFWVSPTAVETAVPYLNLSDGIKMHISVGQGSRRVLERCLGRTV
                     IAPEDGNDSEAVLRLTVWNSLPEGARVLFVRGHGGRDFLMNALQEKGFRTEVAEVYFR
                     RHKPLNFQNFQTENIAAAYITSTELVRLLFGQLPPQFSRFFKSLLYFTHHPRIAEALK
                     REGVCSVETVPTLEAALSHSSISVSDGMVFPGTSN"
     gene            6582..7856
                     /locus_tag="ACFOAE_001069"
     CDS             6582..7856
                     /locus_tag="ACFOAE_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HFC6884570.1"
                     /translation="MPSETSSPRKENETEVHIPAAPFIVKQSGSNALAVCALVLAALG
                     LGTSGFLFVQGQNVLKNQELAFNQKIDKAALGESENAALLKDNLNRQAAIQSELDRLD
                     GNVKANGEQILEMQKSYRELTKGRADWLVDETETILNLAAQQLVLTGNIQTAVGVLEH
                     IDSRLSRFNQAELLPIKQAVSSDLAELKNRPYVDISGTALRLDRLETAVSGLPLMLDG
                     VLKPGVQVKNEAASASWWQNVWEKSLGTLKGLVEIRRLENNDAMLLSPEQAYFVRENL
                     RLRLLDARIALMQRNGEVYQGDLNNAEAAVRQYFDAKSPATQSWLKELAELKALDVRM
                     TADDGLKNSLNAVRAYRDGTRMTAAENQEAEQAASEPANENTASEPAAASDVKTIEAP
                     SLPSERKPEQPAKKQPVPEKAGRSPSAKGERA"
     gene            7853..9070
                     /locus_tag="ACFOAE_001070"
     CDS             7853..9070
                     /locus_tag="ACFOAE_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme biosynthesis protein HemY"
                     /protein_id="HFC6884571.1"
                     /translation="MKTVVWIVVLFAAAVGLALASGIYTGDVYIVLGQTMLRINLHAF
                     VLGSLIAVVVWYFLFKFIIGVFNIPEKMQRFGSARKGRKAALALNKAGLAYFEGRFEK
                     AELEASRVLVNKEAGDNRTLALMLGAHAAGQMENIELRDRYLAEIAKLPEKQQLSRYL
                     LLAESALNRRDYEAAEANLHAAAKMNANLTRLVRLQLRYAFDRGDALQVLAKTEKLSK
                     AGALGKSEMERYQNWAYRRQLADAADAAALKTCLKRIPDSLKNGELSVSVAEKYERLG
                     LYADAVKWVKQHYPHNRRPELLEAFVESVRFLGERDQQKAIDFADAWLKEQPDNALLL
                     MYLGRLAYGRKLWGKAKGYLEASIALKPSISARLVLAKVFDETGEPQKAEAQRNLVLA
                     SVAEENRPSAETH"
     gene            9145..10209
                     /gene="hemE"
                     /locus_tag="ACFOAE_001071"
     CDS             9145..10209
                     /gene="hemE"
                     /locus_tag="ACFOAE_001071"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004853 - uroporphyrinogen decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HFC6884572.1"
                     /translation="MTLLKNDTFLRALLKQPVEYTPIWMMRQAGRYLPEYKATRAKAG
                     SFLDLCKNTELATEVTIQPLERFDLDAAILFSDILTVPDAMGLGLYFAEGEGPKFKRA
                     LQHEDDIAKLHVPDMEKLQYVFDAVTSIRKALDGRVPLIGFSGSPFTLACYMVEGGSS
                     KEFRTIKTMMYSRPDLLHKILDTNAQAVTAYLNAQIDAGAQAVQIFDTWGGVLSDAAF
                     KEFSLKYIRQIVAGLKRESEGRRVPVIVFAKGGGLWLESMAEIGADALGLDWTCNIGE
                     ARRRVGKQVALQGNFDPFALFGTPESIRTEVARILADYGHGSGHVFNLGHGINQHADP
                     EHAKILVDTVHELSRQYHGG"
     gene            10398..11777
                     /gene="radA"
                     /locus_tag="ACFOAE_001072"
     CDS             10398..11777
                     /gene="radA"
                     /locus_tag="ACFOAE_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFC6884573.1"
                     /translation="MAKTLKTLYQCTECGGTSPKWQGKCPHCGEWNTLQESLAAPEPK
                     NARFQSWAADTSTVQSLSAVTATEVPRNPTGMGELDRVLGGGLVDGAVILLGGDPGIG
                     KSTLLLQTIAKMAQSRKVLYVSGEESAQQVALRAQRLELPTDGVNLLAEIRMEAIQAA
                     LKQHQPEVVVIDSIQTMYSDQITSAPGSVSQVRECAAQLTRMAKQMGIAMILVGHVTK
                     DGAIAGPRVLEHMVDTVLYFEGDQHSNYRMIRAIKNRFGAANELGVFAMTENGLKGVS
                     NPSAIFLASYRDDTPGSCVLVTQEGSRPLLVEIQALVDDAHGFTPKRLTVGLEQNRLA
                     MLLAVLNRHGGIACFDQDVFLNAVGGVKIGEPAADLAVILAMLSSFRNRPMPEKTVVF
                     GEIGLSGEVRPVARGQERLKEAEKLGFKRAIVPKANMPRNAKEFPNLKIYGVSSLQEA
                     IDICREDRD"
     gene            complement(12049..12528)
                     /locus_tag="ACFOAE_001073"
     CDS             complement(12049..12528)
                     /locus_tag="ACFOAE_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF302 domain-containing protein"
                     /protein_id="HFC6884574.1"
                     /translation="MKHILPLIAASALCISTASAHPAGEPSTQNETAMTTHTLTSKYS
                     FDETVSRLETAIKSKGMDIFAVIDHQEAAHRNGLTMQPAKVIVFGTPKAGTPLMVKDP
                     AFALQLPLRVLVTETDGKVRAAYTDTRALIAGSRIGFDEVANTLANAEKLIQKTVGE"
     gene            complement(12653..13012)
                     /locus_tag="ACFOAE_001074"
     CDS             complement(12653..13012)
                     /locus_tag="ACFOAE_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFC6884575.1"
                     /translation="MNIKHLITAALIASAAFAAQAAPQKPVSAAQTAQHSAVWIDVRS
                     EQEFSEGHLHNAVNIPVDQIVRRIHEAAPDKDTPVNLYCRSGRRAEAALQELKKAGYT
                     NVANHGGYEDLLKKGMK"
     gene            complement(13051..16665)
                     /gene="recB"
                     /locus_tag="ACFOAE_001075"
     CDS             complement(13051..16665)
                     /gene="recB"
                     /locus_tag="ACFOAE_001075"
                     /EC_number="3.1.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009338 - exodeoxyribonuclease V complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008854 - exodeoxyribonuclease V activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HFC6884576.1"
                     /translation="MSAPIQAFDPLTVPIAGTNLIEASAGTGKTYGIAALFTRLIVLE
                     QKNVERVLVVTFTKAATAELKTRLRARLDDVLQVLESKEIAKLGDDTLSDGIAAYCAE
                     HHKGDTFLPALLKQALQKEGRTRLIVRLKAAIGQFDNAAIYTIHGFCQRILRDYAFLC
                     QAPFDVELTEEDGDRLLVPAQDFWRERVSNDPVLAALAFKRKAVPQTVLAQIRAYLSR
                     PYLNFRRPQADLKQAQRNAETSWQTVCRLLPELEAGFWRIHPDLNGNSYRKNSFGNLF
                     KELAQKSAAGQLPFLDKDTHDRLLKLASDKLEAGLKKGKTPDAAVFAELQKLADFRRD
                     LDALEEAEEATIIRLQLDLIGYLNRSLAEMKKSRRERGFDDLLLDVHTALTDNPHAET
                     LARAVAENWETALIDEFQDTDPLQYEIFQKIFIAQNRPLFLVGDPKQAIYSFRGADIY
                     AYLQAAEDARHRYTLATNYRSHAALIGSIGALFRLKERPFVLENIGYSEVGAARAESR
                     LSPERPAVQVRWLHENDNEKANKDVLRRRAADYCADEIAHALNEAAECRLNFKGCPLQ
                     SGDIAVLVRTHNEAVMVSAALKKRQVQSVLLSRESVFASPEAAALSALIGFWLEPRRA
                     GTLRFVLTSSIFGYNAQQLHDFNQNESEILHWAESARTALDNWNQYGIFAAMQQFSQT
                     HGIETRLLSRNNGRSLTNYFQLLELLAAEDAQNRNPAALHKWLRDQISLAGNNSGDNR
                     AIRLESDEDLVKIVTMHASKGLQYPLVYCPFAWDAQDTGPSDWQILHQSANRTELLAK
                     AQLSEDEQKQYADEEMAERLRLLYVALTRAEEQLNIYAAYSSDTADNPLAYLIEGLPQ
                     DSRETVRRAYACEKDGITMLKRNWQRVTDNAPADTNFSFTEDAPPPAVYCGNAGQTAE
                     FAASDIPKRGFRFIRHTSFTALSRQTQTPDGGEEDACPSLDAAETSVAAMPSETPTAS
                     DGISIHNFPKGTQAGLCLHEILEDFKFGQAAAGQETLIADKLKKYGFEEIWLPAVAEM
                     AEACRKTPLTGAYCLSDIPPECRCPEMGFTLHTEDFGLKRLRDWLTRDDIRLPEVCRA
                     AAETLDFHTVNGFLNGFVDMVCQDPDGNICVIDYKSNHLGADASAYTQQAMDEAVAHH
                     HYYLQALIYAVAAMRYFKLRGQPPAAVSVRYLFLRGFDGKGGGVWHWDIDAAALEQIK
                     "
BASE COUNT         3828 a         4353 c         4800 g         3738 t
ORIGIN      
        1 ttttggtaga atgggaaggt acagattgtt tgaagattag gggacgagga tgtttaccga
       61 tgaaaatatg accgcaaagg aagaactgtt cgcatggctg cgccatatga accaaaacaa
      121 aggttccgac ctgttcgtga cgacccattt cccgcccgcg atgaagttgg acggcaaaat
      181 cacccgcatc acggacgagc cgctgacggc ggaaaaatgt atggaaatcg ccttttcgat
      241 tatgagtgcg aagcaggcgg aagaattttc atcgaccaac gagtgcaact tcgccatcag
      301 tctgccggac accagccgct tccgcgtcaa tgcgatgata cagcgcggcg cgacggcgtt
      361 ggtattccgt gcgattacca gcaagattcc caagtttgaa agcctgaacc tgccgccggt
      421 cttgaaggat gtcgcgctga aaaaacgcgg gctggttatt tttgtcggcg gcaccggctc
      481 gggcaaatcg acttcgcttg cctcgcttat cgactaccgc aatgaaaatt cgttcggaca
      541 catcatcacc atcgaagacc cgatcgagtt tgtccacgaa cacaaaaact gcatcatcac
      601 ccagcgcgag gtcggcgtgg atacggaaaa ctggatggcg gcgttgaaaa acacgctgcg
      661 tcaggcgccg gatgtcatcc ttatcggcga aatccgcgac cgcgaaacga tggactacgc
      721 cattgccttt gccgaaacgg ggcatttgtg tatggcgacg ctgcacgcca acagcaccaa
      781 tcaggcactc gaccgcatca tcaacttttt ccccgaggag cggcgcgaac aattgctgac
      841 ggatttgtcg ctcaaccttc aggcgtttat ttcgcaacgc ctcgttccgc gagacggcgg
      901 caagggcagg gtggcggcag tcgaggtgct gctcaattcg cccctgattt cggagttgat
      961 tcacaacggc aacatccatg aaatcaaaga agtgatgaaa aaatccacta ccttgggtat
     1021 gcagaccttc gaccaacacc tttaccaatt gtatgaaaaa ggcgagattt ccttgcagga
     1081 tgccttgaaa aatgccgatt ccgcacacga tttgcgtttg gcggtgcagt tgcgcagccg
     1141 ccgcgcgcaa agttccagcc ccgatttgga actgctctga tggcggtatg gatttccgga
     1201 cggatggttt gaaatgattt atccgtggca taatgagcaa tggcggcaga ttgcggaaca
     1261 ttgggagcgt cgtcccaatg catggctgtt tgccggcaaa aaagatacgg ggaaaactac
     1321 atttgcccgc tttgcggcga aggcactgtt gtgcgaaacc cctgcaccgg gctgcaaacc
     1381 ctgtggcgaa tgtatgtcct gccatctgtt tggacaggga agccatcccg atttttacga
     1441 aatcaccccc ttgtcggacg aacccgaaaa cggacgcaaa ctgttgcaga tcaaaatcga
     1501 tgccgtcagg gaaatcatcg ataatgtgta cctgacttcg gtacggggcg gtttgcgcgt
     1561 gattctgatt catcctgcgg aaagtatgaa tgtccaagcc gccaacagtt tgttgaaagt
     1621 gttggaagag ccgccgccac aagtggtctt tttgctggtc agccacgcgg cggacaaggt
     1681 tttaccgacc attaaaagcc gctgccggaa gatggttttg cccgcgcctt cccatgaaga
     1741 ggcattggca tatctgcgtg aaaggggtgt ggcggaacct gaggaacgtc tggctttcca
     1801 ttccggagcg ccgctgtttg atgaggcgga cggtgtccgt gcgttgcgga ttaaactgtt
     1861 ggatattttg gcagaaccaa ggttgttgaa gattttggat tacgccgcgc ttttcgataa
     1921 ggaaaaactt ccgctcgccg tatttgtcgg gtggatgcag aaatggctgg tcgatttggg
     1981 attgtgcctg caacacatga aacccgtcta ttatcccgct tatgaagaca ggctgcttca
     2041 gacggtatcc ggtttccgtc cgcgcaatgt atttgcggcg gaggatatgc tcaaacagct
     2101 tgccccctac gggtttcata ctttaaatgt caaaatgcag atcgagcatc tgctcatcaa
     2161 ctatttggaa ttgaagaaag agaacgggtg aattatgtca gacggacaaa atattccggc
     2221 aaaaatgatg tcgttgcagc tgaaagacat gaatctgctg tacagctcct acatgccgtt
     2281 tttggaacac ggcggtctgt ttgtgcagac caacgacgta ttttccatcg gggacgatat
     2341 tctgcttgcc gtagaaatcc tcaacttccc caaactgttc ctgccgacca aagtcgcctg
     2401 gatcaatcct gcgcgtactt cctccaaacc caaaggggtg gggctggcat tcacaaaaca
     2461 cgaaaactgc ctgaaagtca aagaccagat cgaagtcgaa ctgggcaaca caatcggcgg
     2521 cagcagacct acgtttacca tgtaacgcca tgcatatcat cgattcgcac tgccacctca
     2581 attttgaagg tttgaaagaa cgcctgcccg aagttttgtc caacatggaa gcaaacggcg
     2641 tggggcaggc gctcgccatc agcgtcagca gggaaagttt tgccgaagta tccgctatcg
     2701 ccgaagttta tgaacatatt tactgcacaa taggcgtaca tcccgacagc aaggaagccg
     2761 aagaattttc tattgcggaa atggttgctg cagccgccca tccgaaagtg gtcggcattg
     2821 gcgagacggg cttggattat tactggtgca aaggcgattt gtcctggcaa cacaaacgct
     2881 ttgcagacca catcgaagca gccaatcaaa ccggactgcc cgttatcgtc catacgcgtg
     2941 atgcggcggc ggacaccttg tctatcctga aagaatgccg ggttaattcg ggcgttatcc
     3001 actgtttttc cgaagacatc ggttttgccc gtgcagcaat ggatttgggg ctttatattt
     3061 ctttctcggg aatcgttacc tttaaaaacg cacccttggt tcaggaggcg gcaaaatacg
     3121 ttccggacga ccgcattttg gtggaaaccg atgcgccgtt cctcgccccc gttcccaaac
     3181 gcggcaggca gaacgaaccg gcttttgtgc gccataccgc cgaacatatc gccaaattgc
     3241 ggaaccaaac attggaacag gttgcggcat atacgacgga aaacttttac cggctgttta
     3301 aaaaagtacc cgatatgcgg gccgtctgac cctgtaccga cgataaggaa aaccatgaag
     3361 gcaattcatc cgtatgcatg tccgcgctgc tgccggctgc ctgccaacac gtttcggaca
     3421 ggcatggcaa attccgcttc caaattctgc attgccaaag gcggcagacg ggaagcaaaa
     3481 aagacgaaag cggcggcgga tatgccctgt gccatttgcc ggacagcagg attgtcgagg
     3541 agtgggaata tttccgttca caacattgat actgcgcgat atacggcaaa tattgtggga
     3601 agtttccgct tttgcgtata atgcgtccta cctgacaaat tttgtcaact ttatcaaaag
     3661 gaataagcga tggcttccat ccacgaccaa attaaagaag tagtaacgac acaccgcgtc
     3721 gtattgttta tgaaaggtac gaagcagttt ccgcaatgcg gtttctcttc ccgcgccgtg
     3781 caaatcctga acgcggcagg ctgcaccgat tacgttaccg tcaacgtatt ggaaaatccc
     3841 gaagtacgcc aaggcattaa ggaatacagc gactggccga ccatccccca actttatgtg
     3901 aacggcgagt ttgtcggcgg ttcggacatc ctgatggaaa tgtatgaggc aggcgagctg
     3961 caagagctgc tgaaagcctg atggattcgg caatgccgtc tgaacgtgtt tcagacggca
     4021 ttttcttttc cggcaaatca aaaaaaagta taatggcgcg tctcaaaatc acactggaac
     4081 accgcgatga acgttaatgt tatcaaccat ccgctcgtcc gccacaaatt aaccctgatg
     4141 agggaggcgg attgcagcac ctacaaattc cggacgcttg ccatcgagct ggcgcgcctg
     4201 atggcatacg aggcaagccg tgattttgaa atcgaaaaat accttatcga cggatggtgc
     4261 ggtcagattg aaggcgaccg catcaagggc aaaacattga ccgtcgttcc catactgcgt
     4321 gcaggtttgg gtatgcttga cggcgtactc gacctgattc cgactgccaa aatcagcgta
     4381 gtcggactgc agcgcgacga ggaaacgctg aaacccgttt cctacttcga gaaattcgtg
     4441 gacagcatgg acgaacgtcc tgccctgatt atcgacccga tgctggcgac aggcggttcg
     4501 atggttgcca ccatcgacct gttgaaagcc aagggctgca aaaacatcaa ggcactggtg
     4561 ctggttgccg cgcccgaggg tgtgaaggcg gtcaacgacg cgcatcccga cgttacgatt
     4621 tacaccgccg cgctcgacag ccacttgaac gagaacggct acatcatccc cggcttgggc
     4681 gatgcgggcg acaagatttt cggcacgcgc taactgactg attttcggat ttgatatgaa
     4741 tttccaagac tatctcgcca catttccttc aatcgaccat ctgggcggtt tggacgttca
     4801 ggatgccgac ggcaaaacgg ttcaccacat tcccgccgtt cagggtaagc tcggttcgct
     4861 caagctgtac aatgctttgg cagaacgttt tgacggaaaa ttggacaaag aagcggcaga
     4921 acagggtttg atatggtttg ccgaacacgt tgccgacgcg cgcgcccatc ccggcaagca
     4981 tcccaatatc gacctgcttg aaaaagttgt gcaaagcggc gaaaccttgc tgctcaagcc
     5041 gcttgccgcg caataatttt cgaccatgcc gtctgaaatc cgtttcagac ggcattttgt
     5101 cggaaagaag accgtaaaac gggcattttc ttttctattt caggatacgg gcaatgatgt
     5161 ttcaacacac aggacgacac ataaagcgtt gccctatgtg ttgccctaat ttggaagagg
     5221 ttacaccctt tcaaataaaa tctgatgctg ccgccacgaa ggacggatgt ccaagtggcg
     5281 gggttttaac cattaaggaa atacgatgaa aaaaacgttc ctttctgccg tattgcttct
     5341 gtcagctgcg acccaaaccg tgtgggcaga tacggtgttt tcctgtaaaa cggacaacaa
     5401 caaatatata gaagttcaaa aaattaaccg caatctttac gaatattcgt tcggcagtgc
     5461 ggcaaaaaaa gaaattgcca tacgcaacag caaagctgat ctgttggggc gttccgacag
     5521 gtggcaaggc tggggcagag gccgttgggc gacgatgaaa ttccaaaacg gcgaatttat
     5581 gtacaccata tggacaggct tcgattccgt gactcatacg gaaagcagcg gtgtcgttgt
     5641 ggagcgtagg ggcaaggaag tcgcacgggt tggctgtacg ccgcaaaccg cgcaggcgaa
     5701 tttcaacgat gctgattttt cccggtaatc ggggcggata aggcgatgga aacagtgaaa
     5761 cccatcatgc tgattgtccg accgtcgggc agggcgaagg acgatgtgga aacctgccgt
     5821 cgtgccggat ggcaggcgga agtgttgagc ccgattgaaa tcgaagcaga tgctgccgga
     5881 ctggaacttt tgtccgaaca atatgcccgt gcggatgccg tgttttgggt cagtccgacc
     5941 gccgttgaaa ccgccgtccc gtaccttaac ctttcagacg gcataaagat gcacatttcc
     6001 gtagggcagg gcagccgccg cgtattggaa cgctgtttgg gcagaacggt catcgcgcct
     6061 gaagacggca acgacagcga ggcggttttg cgcctgacgg tttggaacag tctgcccgaa
     6121 ggtgcgcgcg tattgtttgt gcgcggacac ggcgggcggg attttctgat gaatgccttg
     6181 caggagaaag gttttcggac ggaggtggca gaagtctatt tcagacggca taaacctttg
     6241 aactttcaaa atttccaaac cgaaaatatt gccgccgcct atattacgtc cacagaactc
     6301 gtgcgcttgc tgttcggaca gcttccgccg caattttccc gattcttcaa atccttgcta
     6361 tactttaccc atcatccgcg cattgcggag gcattgaagc gcgaaggcgt gtgttcggtc
     6421 gaaaccgtcc ctacgctgga agccgcgctt tcccattctt ccatttccgt ttcagacggc
     6481 atggtctttc ccggaacctc aaattaataa ggagcaaaac ggtgggcgaa cctgaaaaca
     6541 aatcatccga acccgtacgc gagatacagg catcaaaaga aatgccgtct gaaacctctt
     6601 ccccacgcaa agaaaacgaa acagaagtac acattcctgc cgctcctttt atcgtcaaac
     6661 agtccggcag caacgctttg gcagtctgcg ccctggtatt ggcggcattg ggtttgggta
     6721 caagtggttt tttgtttgtc caaggacaga atgtcttgaa aaaccaagag ctggcattca
     6781 accaaaaaat cgacaaagcc gccttgggcg agtcggaaaa cgccgccctg ttgaaagaca
     6841 acctcaaccg gcaagccgcc atacaatcag agctcgaccg tttggacgga aacgtcaaag
     6901 caaacggcga acaaatcttg gaaatgcaaa aatcctatcg cgagttgacc aaaggacgcg
     6961 ccgattggct ggtggacgaa accgagacca tactcaatct ggcggcgcaa cagctggtgt
     7021 tgactggcaa tatccaaacg gcagtcggcg tattggagca tatcgacagc cgcctgtccc
     7081 gtttcaatca ggcagagctt ctgccgatca agcaggcggt cagcagcgac ttggcggaac
     7141 tgaaaaaccg tccctatgtc gatatttccg gcacggcatt gcgcctcgac aggctggaaa
     7201 ccgccgtatc cggactgccg ctgatgctcg acggcgtatt gaaaccgggc gtacaggtga
     7261 agaacgaagc cgcttctgct tcatggtggc agaacgtatg ggaaaaatcc ctcggcacat
     7321 tgaaggggct ggtcgaaatc cgccgtttgg aaaacaacga tgccatgctg ctttcaccgg
     7381 aacaggcata ttttgtgcgt gaaaacctgc gcctccgcct tttggatgcg cgcattgcat
     7441 taatgcagcg caacggcgaa gtctatcagg gcgatttgaa caatgccgaa gccgccgtca
     7501 gacagtattt cgatgccaag tctcccgcca cgcagtcgtg gctgaaagaa ctggcggaat
     7561 tgaaggcgtt ggatgtgcgc atgacggcgg atgacggttt gaaaaacagc ctaaatgccg
     7621 tccgcgccta tcgcgacggt acgcgcatga cggcggcgga aaatcaagaa gcggaacagg
     7681 cggcttccga accggcaaac gaaaacacag cttccgaacc ggctgccgca tcggatgtga
     7741 agaccataga agcaccgtcc ctgccttcgg aacgcaaacc ggaacagcct gcaaaaaaac
     7801 agcccgtacc ggaaaaggca gggcgttcgc cgtccgctaa aggagaacgc gcatgaaaac
     7861 ggtagtctgg atcgtcgtcc tgtttgccgc cgccgtcgga ctggcactgg cttcgggcat
     7921 ttacaccggc gacgtgtata tcgtactcgg acagaccatg ctcagaatca acctgcacgc
     7981 ctttgtgtta ggttcgctga ttgccgtcgt ggtgtggtat ttcctgttca aattcattat
     8041 cggcgtattc aatatccccg aaaagatgca gcgtttcggt tcggcgcgta aaggccgcaa
     8101 ggccgcgctt gccttgaaca aggcgggttt ggcgtatttt gaagggcgtt ttgaaaaggc
     8161 ggaactagaa gcctcacgcg tgttggtcaa caaagaggcc ggagacaacc ggactttggc
     8221 attgatgttg ggcgcacatg ccgccgggca gatggaaaac atcgagctgc gcgaccgtta
     8281 tcttgcggaa atcgccaaac tgccggaaaa gcagcagctt tcccgttatc ttttgttggc
     8341 ggaatcggcg ttgaaccggc gcgattacga agcggcggaa gccaatcttc atgcggcggc
     8401 gaagatgaat gccaacctta cgcgcctcgt gcgtctgcaa cttcgttacg ctttcgacag
     8461 gggcgacgcg ttgcaggttc tggcaaaaac cgaaaaactt tccaaggcgg gcgcgttggg
     8521 caaatcggaa atggaacggt atcaaaattg ggcataccgc cgccagctgg cggatgctgc
     8581 cgatgccgcc gctttgaaaa cctgcctgaa gcggattccc gacagcctca aaaacgggga
     8641 attgagcgta tcggttgcgg aaaagtacga acgtttggga ctgtatgccg atgcggtcaa
     8701 atgggtcaaa cagcattatc cgcacaaccg ccgacccgaa cttttggaag cctttgtcga
     8761 aagcgtgcgc tttttgggcg aacgcgatca gcagaaagcc atcgattttg ccgatgcttg
     8821 gctgaaagaa cagcccgata atgcgcttct gctgatgtat ctcggtcggc tcgcctacgg
     8881 ccgcaaactt tggggcaagg caaaaggcta ccttgaagcg agcattgcat taaagccgag
     8941 tatttccgcg cgtttggttc tggcaaaggt ttttgacgaa accggagaac cgcagaaggc
     9001 ggaggcgcag cgcaacttgg ttttggcaag cgttgccgag gaaaaccgac cttccgccga
     9061 aacccattga aactttcaga cggcatcgtt gaaatgccgt ctgaaaacca tttcacttga
     9121 caaacagact gacagaaaac ccgtatgact cttttaaaaa acgatacctt cctccgcgcc
     9181 ctgcttaaac agcccgtcga atacacgccg atttggatga tgcgtcaggc ggggcgttat
     9241 ctgcccgaat acaaagccac acgcgcgaaa gcgggcagct tcctcgattt gtgcaaaaac
     9301 accgaattgg cgaccgaagt taccatccaa cctttggaac gtttcgattt ggacgcggcg
     9361 attttgtttt ccgacatcct gaccgtcccc gacgcaatgg gcttgggact gtattttgcc
     9421 gaaggcgaag gcccgaaatt caaacgcgcc ctgcaacacg aggacgacat tgccaaattg
     9481 cacgtccccg atatggaaaa actgcaatac gttttcgacg cggtaacttc catccgtaaa
     9541 gcattggacg gccgcgtacc gcttatcggc ttctccggca gtccgttcac gctcgcctgt
     9601 tacatggtcg aaggcggcag cagcaaagaa ttccgcacca tcaaaaccat gatgtactcg
     9661 cgccccgatt tgctgcacaa aatcctcgat accaacgccc aagccgttac cgcctacctc
     9721 aacgcccaaa tcgacgcggg cgcgcaggct gtgcagattt tcgacacttg gggcggcgtc
     9781 ttgagcgatg cggcgtttaa agaattcagc ctcaaataca tccgccaaat tgttgccgga
     9841 ctgaaacgcg aaagcgaagg caggcgcgtg cctgtcatcg tgtttgccaa aggcggcggg
     9901 ctgtggctgg aaagcatggc agaaatcggc gcagacgcat tgggcttgga ctggacgtgc
     9961 aacatcggcg aagcacgccg ccgcgtcggc aagcaagtcg ccctgcaagg caacttcgac
    10021 ccgtttgctc tctttggcac acccgaatcc atccgcaccg aagtcgcgcg catcctagcc
    10081 gactacggac acggcagcgg ccacgtcttc aatctcggac acggcatcaa ccaacacgcc
    10141 gaccccgaac acgccaaaat cttagtcgat accgtacacg agctgtctcg gcagtatcac
    10201 ggcgggtaag ccggcaggaa accgcccgat atgccgtctg aagccgagag atggccggtt
    10261 agggtaaaaa taaggcaatg cggcaatatc cgccgtgtat ggatagtaca tgacggcggc
    10321 ggcgttgtcg tattggcgca atcccaaccg tccctatttt cagacggcat ttttgttttc
    10381 agatgcaggg aaaaccgatg gcaaaaacgc ttaaaaccct ttaccaatgc accgaatgcg
    10441 gcggcacctc cccgaaatgg caaggcaaat gcccgcattg cggcgagtgg aacacgcttc
    10501 aggaaagcct tgccgcgccc gagccgaaaa acgcccgttt ccaatcttgg gcggcggaca
    10561 cttcgaccgt ccaatccctc tccgccgtta ccgccaccga agtgccgcgc aatccgaccg
    10621 gtatgggcga actcgaccgc gtattgggcg gcggtttggt cgatggtgcg gtcatcctgc
    10681 tcggcggcga ccccggcatc ggcaaatcca cgctgctgtt gcaaaccatc gccaaaatgg
    10741 cgcaaagccg taaagtgcta tacgtttccg gcgaagaatc cgcccaacaa gtcgccctgc
    10801 gcgcgcagcg tttggaactg ccgaccgacg gcgtaaacct tcttgccgaa atccgcatgg
    10861 aagcgattca ggcggccttg aaacagcatc agcccgaagt tgtcgtcatc gactctatcc
    10921 aaaccatgta ttccgaccaa atcacgtccg cccccggctc cgtgtcgcag gtgcgcgagt
    10981 gtgccgccca actgacgcgc atggcgaaac agatgggcat cgccatgata ctggtcggac
    11041 acgtgaccaa agacggcgcg attgccggcc cgcgcgtgct ggaacacatg gttgataccg
    11101 tgctgtattt cgagggcgac cagcattcta attatcgaat gatacgcgcc atcaaaaacc
    11161 gtttcggcgc ggcaaacgaa ttgggcgtat tcgctatgac cgaaaacggt ttgaaaggcg
    11221 tatccaaccc gtccgccatc ttcctcgcca gctaccgcga cgatacgccc ggctcgtgcg
    11281 ttttggttac acaagaaggc agccgcccgc ttttggtcga aattcaggca ttggtcgatg
    11341 acgcgcacgg tttcaccccc aaacgcctca ccgtcggact ggaacaaaac cgccttgcga
    11401 tgctgcttgc cgtgttaaac cgacatggcg gcattgcctg tttcgaccaa gacgtattcc
    11461 ttaacgccgt cggcggcgtc aaaatcggcg aaccggcggc ggatttggca gtcatcctcg
    11521 cgatgctttc cagcttccgc aaccgcccta tgcctgaaaa aaccgtggtt ttcggcgaaa
    11581 tcggcttaag cggcgaagtc cgccccgtcg cacgcgggca agagcggctc aaagaagcgg
    11641 aaaaactcgg ctttaaacgc gccatcgtcc caaaagccaa tatgccgcgc aacgccaaag
    11701 agtttccgaa cctgaaaatc tacggcgttt cgagtttgca ggaagccatc gatatttgtc
    11761 gggaagatag ggattgaaag gaaatgccgt ctgaaggttc agacggcatt tggtttgtgg
    11821 cggattgaaa acaagaaggc ataccggcga cagataagat ttgtggcaaa gttacctgtg
    11881 atatggcaaa aacacacacg cccgtcatcc ccgcaagggt gggaatctgg agtcgtccgt
    11941 ttcggcaatg attgaaaatc acggtaaccc aaccgcttgg attcccgact tcgtgggaat
    12001 gaggggcgtg tgtgtttgat ttccatccgc catatgtcgg cgacgggctt attcgcctac
    12061 ggttttttgt atcagttttt cggcgtttgc caaagtgttt gccacttcgt caaaaccgat
    12121 gcggctgccg gcgatgaggg cgcgcgtatc ggtataggcg gcgcgtactt tgccgtctgt
    12181 ttcggtaacg aggacgcgca ggggcagttg cagggcgaag gcggggtctt tgaccatcag
    12241 cggcgtgccg gctttgggcg tgccgaagac gatgactttt gccggctgca tcgttaagcc
    12301 gtttcggtgg gcggcttcct gatggtcgat gacggcaaaa atgtccatcc ctttgctttt
    12361 tatggcggtt tcaaggcggc tgacggtttc gtcaaaactg tattttgagg tgagggtatg
    12421 cgtggtcata gcggtttcgt tttgggtgga cggttcgccg gcaggatgtg ccgaagcggt
    12481 tgaaatgcag agtgcggatg cggcaatcag ggggagtatg tgtttcatcg tatttcctta
    12541 tcggtttgtt tatcaggctt cggacggggc ggcacgcgcc gcgcccgatg ttgcgccgcg
    12601 tgccggaacg ccgtatgccg tctgaaagcc tgtcctttca gacggcattg cgtcatttca
    12661 tccctttttt gagcaggtct tcataaccgc cgtgattggc aacatttgta taacctgctt
    12721 ttttcagctc ttgaagggcg gcttcggcac gccgtccgct gcggcagtag aggttgaccg
    12781 gcgtgtcttt gtcgggcgcg gcttcgtgta tgcggcggac gatttggtcg acggggatgt
    12841 tgaccgcgtt gtgcaaatga ccttcgctaa attcctgttc gctgcggaca tcgatccaaa
    12901 cggctgaatg ttgcgcggtt tgggcggcgg atacgggttt ttgcggggct gcctgcgcgg
    12961 caaaggcggc tgaggcaatg agtgcggcgg taatcaggtg tttgatattc atagggttct
    13021 cctgcggttg tcgtcttaag ggacgggaag ttattttatc tgttccaaag cggcggcatc
    13081 tatgtcccaa tgccaaacgc cgccgccttt gccatcgaat ccgcgcaaaa acaggtagcg
    13141 gacggaaacg gcggcgggcg gttgtccgcg cagtttgaag tagcgcatgg cggcaacggc
    13201 gtaaatcagt gcttgaaggt aatagtggtg gtgtgcgacg gcttcgtcca ttgcctgttg
    13261 cgtgtaggcg gatgcgtccg cgccgaggtg gttcgacttg tagtcgatga cgcagatatt
    13321 gccgtcgggg tcttggcaga ccatatcgac aaagccgttt aaaaagccgt tgacggtgtg
    13381 gaagtcgagc gtttcggcgg cggcacggca gacttcgggc agcctgatgt cgtcgcgggt
    13441 aagccagtcg cgcagccgtt tgaggccgaa gtcttcggtg tggagggtaa agcccatttc
    13501 gggacagcgg cactcgggcg ggatgtcgga caggcagtat gcccccgtca gcggcgtttt
    13561 gcggcaggct tccgccattt cggcaacggc gggcagccat atttcttcaa aaccgtattt
    13621 tttcagcttg tcggcaatga gggtttcctg tccggcggct gcttgtccga atttgaaatc
    13681 ttcaagaatt tcgtgcaggc acagccccgc ctgcgtgcct ttcgggaagt tgtgtatcga
    13741 tatgccgtct gaagccgtcg gcgtttcaga cggcatcgcc gctaccgagg tttcggcggc
    13801 atccaaggac gggcaggcat cttcttcgcc gccgtcgggc gtttgggttt ggcggcttaa
    13861 ggcggtgaag ctggtgtggc ggatgaagcg gaaaccgcgc ttgggaatgt cggaggcggc
    13921 aaattcggcg gtttgaccgg cgttgccgca atatacggca ggcggcggag catcttctgt
    13981 gaaggagaaa tttgtgtcgg ccggggcgtt gtccgtcacg cgctgccagt tgcgtttgag
    14041 catcgttatg ccgtcttttt cacacgcata ggcacggcgg acggtttcac ggctgtcttg
    14101 cggcaagcct tcaatcaggt aggcgagggg gttgtcggcg gtatcggaag aataggcggc
    14161 gtagatgttg agctgttcct cggcacgcgt cagcgcgaca taaagcaggc gcaggcgttc
    14221 cgccatttcc tcatcggcgt attgcttctg ttcgtcttcc gacagttgcg cctttgccaa
    14281 cagttcggtt cgatttgcgc tttggtggag gatttgccag tcggacggcc cggtatcttg
    14341 cgcgtcccac gcaaacgggc agtacaccag cggatactgc aaacctttcg aggcgtgcat
    14401 ggtaacgatt ttgaccaaat cttcgtcgct ttccagacgg atggcgcggt tgtcgccgct
    14461 gttgttgccg gccaggctga tttggtcgcg caaccatttg tgcagcgcgg cggggttgcg
    14521 gttttgcgcg tcttcggcgg caagcagttc gagcagttgg aaataattgg tcaggctgcg
    14581 cccgttgttc cggcttaaga ggcgcgtttc gatgccgtgt gtttgggaaa attgctgcat
    14641 ggcggcgaaa atgccgtatt gattccagtt gtcgagcgcg gttcgggcag attccgccca
    14701 atgcaaaatc tcgctttcgt tttggttgaa gtcgtgcaat tgctgcgcgt tatagccgaa
    14761 tatgctgctt gtcaggacaa agcgcagcgt tccggcgcgg cgcggttcga gccagaagcc
    14821 gatgagtgcg gaaagggcgg cggcttcggg cgaggcgaac acggattcgc gcgaaagcag
    14881 gacgctttgc acctgccgtt ttttcagggc agcggaaacc atcaccgcct cgttgtgcgt
    14941 gcgtaccagc acggcaatat cgcccgactg caacgggcag cctttgaaat tcagacggca
    15001 ttcggcggct tcgttgagcg cgtgggcgat ttcgtcggcg caatagtcgg cggcacggcg
    15061 gcgcaaaacg tctttgttgg ctttttcatt gtcgttttcg tgcagccaac gaacctgtac
    15121 ggcaggacgt tcgggggaca acctgctttc ggcacgcgcc gcaccgactt ccgaatagcc
    15181 gatgttttcc aaaacgaacg ggcgttcttt gaggcggaac agcgcgccta tgctgccgat
    15241 aagcgcggcg tggctgcggt agttggtggc gagcgtgtag cggtgccgcg cgtcttccgc
    15301 cgcctgaagg taggcgtaaa tgtccgctcc gcgaaagctg taaatcgcct gtttgggatc
    15361 gccgacgagg aacagcggtc ggttttgggc gatgaagatt ttttggaaga tttcgtattg
    15421 cagcgggtcg gtgtcttgga actcgtcgat cagcgcggtt tcccagtttt cggcaacggc
    15481 gcgggcgagg gtttcggcgt gcggattgtc ggtcagcgcg gtgtggacat cgagcagcag
    15541 gtcgtcgaaa ccgcgttcgc ggcgcgattt tttcatctcg gcaaggctgc ggttgaggta
    15601 tccgattaaa tccagttgca gccggattat tgttgcttct tccgcttctt cgagtgcgtc
    15661 caaatcacgc ctgaagtctg ccagtttctg caattcggca aatactgccg catcgggcgt
    15721 tttgcctttt ttcagtccgg cttcgagttt gtcggacgca agtttcaaga gtctgtcgtg
    15781 tgtgtctttg tccagaaagg gcagttgtcc ggcggcggat ttttgtgcca gttctttaaa
    15841 aaggttgccg aagctgtttt tgcggtaact gttgccgttg aggtcgggat ggatgcgcca
    15901 aaagccggct tccagctcgg gcagcaggcg gcagacggtt tgccatgagg tttcggcgtt
    15961 gcgctgcgcc tgtttcaaat ccgcctgcgg acggcggaaa ttcaggtacg ggcgggacag
    16021 gtaggcgcgg atttgggcaa ggacggtttg cggcacagct ttgcgtttaa acgccaatgc
    16081 ggcaagcacc ggatcattgc tgacgcgttc ccgccaaaaa tcttgcgccg ggacaagcag
    16141 gcggtcgccg tcttcttcgg tcagttcgac atcgaacggt gcttggcaca aaaacgcgta
    16201 gtcgcgcagg atgcgctggc agaagccgtg gatggtatag atggcggcgt tgtcgaattg
    16261 cccgatggcg gctttgaggc ggacaatcag acgcgtccgg ccctcttttt gcaaagcctg
    16321 ttttaagagt gcgggcagga aggtgtcgcc tttgtggtgt tcggcgcagt aggcggcgat
    16381 gccgtctgaa agcgtgtcgt ctccaagttt ggcaatttct ttactttcta aaacctgcaa
    16441 cacatcgtcc aaacgtgcgc gcaggcgtgt tttcaactcg gcggtggcgg ctttggtgaa
    16501 ggtaacgacc aatacgcgct cgacgttttt ttgttccaat acgatcaggc gcgtaaacag
    16561 ggcggcaatg ccgtaggttt ttccggtgcc ggcagaggcc tcaatcaggt tggtgccggc
    16621 aatggggacg gtcagcgggt caaatgcttg gatgggtgca gacatagtgc gcgctcggaa
    16681 aacggttgga cggtatagtg gattaacaaa aatcaggat
//
LOCUS       DAXIDM010000040        16481 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000040 DAXIDM010000000
VERSION     DAXIDM010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16481
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.040"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            208..1272
                     /locus_tag="ACFOAE_001076"
     CDS             208..1272
                     /locus_tag="ACFOAE_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HFC6884577.1"
                     /translation="MKAARFHDKGDIRIEDIPEPTVAPGTVGINVAWCGICGTDLHEF
                     MEGPIFIPPCGHPHPISGESAPVTMGHEFSGVVYAVGEGVDDIKVGQHVVVEPYIIRD
                     DVPTGEGSNYHLSKDMNFIGLGGCGGGLSEKIAVKRRWVHPISDKIPLDQAALIEPLS
                     VGHHAYVRSGAKAGDVALVGGAGPIGLLLAAVLKAKGIKVIITELSKARKDKARESGV
                     ADYILDPSEVDVVEEVKKLTNGEGVDVAFECTSVNKVLDTLVEACKPAANLVIVSIWS
                     HPATVNVHSVVMKELDVRGTIAYCNDHAETIKLVEEGKINLEPFITQRIKLDELVSEG
                     FERLIHNNESAVKIIVSPNL"
     gene            1413..1736
                     /locus_tag="ACFOAE_001077"
     CDS             1413..1736
                     /locus_tag="ACFOAE_001077"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004636 - phosphoribosyl-ATP diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-ATP diphosphatase"
                     /protein_id="HFC6884578.1"
                     /translation="MGDSVLSAIQQTITQRKSANPSESYVAQLLHKGEDKILKKVIEE
                     AGEVLMASKDKNPSHLVYEVADLWFHTMILLTHHDLKAEDVLDELARRQGLSGLAEKA
                     ARTES"
     gene            1808..2131
                     /locus_tag="ACFOAE_001078"
     CDS             1808..2131
                     /locus_tag="ACFOAE_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HFC6884579.1"
                     /translation="MDNCIFCKIAAKDIPAQTVYEDGEMVCFKDINPAAPVHLLLIPK
                     VHFDSLAHAAPEHQPLLGKMMLKVPEIAKAAGLADGFKTLINTGKGGGQEVFHLHIHI
                     MGTPV"
     gene            2178..2381
                     /gene="tatA"
                     /locus_tag="ACFOAE_001079"
     CDS             2178..2381
                     /gene="tatA"
                     /locus_tag="ACFOAE_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0043953 - protein transport by the Tat
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HFC6884580.1"
                     /translation="MGSFSLTHWIIVLIIVVLIFGTKKLRNVGKDLGGAVHDFKQGLN
                     EGTDGKEAQKDDVIEHKKDEDKA"
     gene            2385..3071
                     /gene="tatB"
                     /locus_tag="ACFOAE_001080"
     CDS             2385..3071
                     /gene="tatB"
                     /locus_tag="ACFOAE_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008320 - protein transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase protein
                     TatB"
                     /protein_id="HFC6884581.1"
                     /translation="MFDFGLGELVFVGIIALIVLGPERLPEAARTAGRLIGRLQRFVG
                     SVKQEFDTQIELEELRKAKQEFEAAAAQVRDSLKETGTDMEGNLHDISDGLKPWEKLP
                     EQRTPADFGVDENGNPLPDAANTLSDGISDVMPSERSYASAETLGDSGQTGSTAEPAE
                     TDQDRAWREYLTASAAAPVVQTVEVSYIDTAVETPVPHTTSLRKQAISRKRDLRPKSR
                     AKPKLRVRKS"
     gene            3085..3855
                     /gene="tatC"
                     /locus_tag="ACFOAE_001081"
     CDS             3085..3855
                     /gene="tatC"
                     /locus_tag="ACFOAE_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HFC6884582.1"
                     /translation="MSETQNEQPVQPLVEHLIELRRRLMWTVVGILVCFFGLMPFAQQ
                     LYTFIADPLMANLPKDTSMIATDVIAPFFVPVKVTLMAAFLISLPHTLYQIWAFVAPA
                     LYQNEKRLITPLVLSSVSLFFIGMAFAYFLVFPVIFKFLASVTPVGVNMATDIDKYLS
                     FILGMFVAFGTTFEVPIVVILLTKIGVVTTEQLKRARPYVIVGAFVIAAVITPPDVIS
                     QTLLAIPLILLYEAGIWFGRFFTPRSEQDGDIQPPATT"
     gene            3908..4513
                     /locus_tag="ACFOAE_001082"
     CDS             3908..4513
                     /locus_tag="ACFOAE_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030428 - cell septum [Evidence IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0000917 - division septum assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Maf family nucleotide pyrophosphatase"
                     /protein_id="HFC6884583.1"
                     /translation="MNTLYLGSNSPRRMEILTQLGYQVVKLPADINETVRQNEDPARY
                     VQRMAEEKNRTALTLFCETNGTMPDFPLITADTCVVSDGIILGKPRSQAEAATFLNLL
                     SGTGHTVLTAVCIHYRGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAVQG
                     IGGIFIQSIEGSFSGIMGLPVYETVSMLQDLGYRTPPFIRA"
     gene            4529..4882
                     /locus_tag="ACFOAE_001083"
     CDS             4529..4882
                     /locus_tag="ACFOAE_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2069 domain-containing protein"
                     /protein_id="HFC6884584.1"
                     /translation="MNRQTAYLLTSFSLIALIILSLSWELWIAPLRPGGSWLALKALP
                     LCLPLSGILKKKIYTYQYSSMLVLIYFAEAVMRLFDAYPAEQICAALSAVFSIIFFIS
                     CLSFVKQYKETNNAR"
     gene            4872..6686
                     /locus_tag="ACFOAE_001084"
     CDS             4872..6686
                     /locus_tag="ACFOAE_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Wzy polymerase domain-containing protein"
                     /protein_id="HFC6884585.1"
                     /translation="MPAETTVSGAHPAAKLPIYILPCFLWIGIVPFTFALKLKPSPDF
                     YHDAAAAAGLIVLLFLTAGKKLFDVKIPAISFLLFAMAAFWYLQARLMNLIYPGMNDI
                     VSWIFILLAVSAWACKSLVAHFGQERIVTLFAWSLLIGSLLQSCIVVIQFAGWEDTPL
                     LQNLIVYSGQGVIGHIGQRNNLGHYLMWGILAAAYLNGQRKIPPALGAICLIMQTAVL
                     GLVNSRTILTYIAAIALILPFWYFRSDKSNRRTMLGIAAAVLLTALFQFSMNTILETF
                     TGIRYETAVERVANGGFTDLPRQIEWNKALAAFQSAPIFGHGWNSFAQQTFLINAEQH
                     NIHDNLLSNLFTHSHNIVLQLLAEMGISGTLLVAATLLTGIAGLLKRPLTPASLFLIC
                     TLAVSMCHSMLEYPLWYVYFLIPFGLMLFLSPAEASDGIAFKKAANLGILTASAAIFA
                     GLLHLDWTYTRLVNAFSPATDDSAKTLNRKINELRYISANSPMLSFYADFSLVNFALP
                     EYPETQTWAEEATLKSLKYRPHSATYRIALYLMRQGKVAEAKQWMRATQSYYPYLMPR
                     YADEIRKLPVWAPLLPELLKDCKAFAAAPGHPEAKPCK"
     gene            6876..7553
                     /gene="misR"
                     /locus_tag="ACFOAE_001085"
     CDS             6876..7553
                     /gene="misR"
                     /locus_tag="ACFOAE_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator MisR"
                     /protein_id="HFC6884586.1"
                     /translation="MSRVLLVDDDALLTELLTEYLSAEGLNVRSVPDGEAGVQEILSG
                     QYDVVVLDSMMPKMNGLDVLKNVRARSTVPIIMLTAKGDDIDRIIGLEMGADDYVPKP
                     CTPRELLARINAILRRAQHSGEQNNAPNSISVSDVVLYPAKRQASVKDMPLELTSTEF
                     NLLEVLMRHAGQVVSKETLSVEALDRKLAKFDRSIDVHISSIRHKLGDASLIQTVRGL
                     GYLFVKN"
     gene            7566..8972
                     /gene="misS"
                     /locus_tag="ACFOAE_001086"
     CDS             7566..8972
                     /gene="misS"
                     /locus_tag="ACFOAE_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     MisS"
                     /protein_id="HFC6884587.1"
                     /translation="MKLFQRIFATFCAVIVCAIFVASFSFWLVQNTLAENQFNQRRTI
                     ETTLMGSIISAFRARGDAGAREILTEWKDSPVSSGVYVIQGDEKKDILNRYIDSYTIE
                     RARLFAAGHPHSNLVHIEYDRFGEEYLFFTKDWDKLQARRLPSPLLIPGLPLAPIWHE
                     LIILSFIIVVGLLMAYILAGNIAKPIRILGNGMDRVANGELETRISQQVDDRDDELSH
                     LAIQFDKMVEKLEKLVAKERHLLHHVSHEMRSPLARMQAIVGLIQAQPQKQEQYLKRL
                     EGELTRMDTLAGELLTLSRLETSNMALEKESLKLLPFLGNLVEDNQSIAQKNGQTVTL
                     SADGKIPENTTILANESYLYRAFDNVIRNAVNYSPEGSTILINIGQDHKHWIIDVTDN
                     GPGVDEMQLPHIFTAFYRADSSANKPGTGLGLALTQHIIEQHCGKIIAENIKPNGLRM
                     RFILPKKKTGSKTEKSAN"
     gene            9090..11516
                     /locus_tag="ACFOAE_001087"
     CDS             9090..11516
                     /locus_tag="ACFOAE_001087"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC6884588.1"
                     /translation="MSAQTDPGYFFMPNHIILIGASERPYSLGERVLSNLLSTPFQGK
                     ITPVNPRHHTIAGLPAYTSLNKIPGNADLIIAVTLPDSYDTLFKTCRKKQLRHIILIQ
                     DWDSLPAAELHTAETAIRKHHGNGLNITACTTAGIQLPSLGLNISTQDGYAAGHTAIL
                     TGNAAVSRQIDNILNKLRQGTSRHISLHPGISPITSSDWLNRFGHSLHTKTAVLHHNP
                     EEDQRKLFSAIRQFTRHTPLILHITCRTTETDRAVLHCLARHCNFLISFNADDLEAAL
                     RAQLSDLPPLSRLDILSDTPAEWLNAHAPKTLALHFPNLPHHIRNGHLTGTPTPSICH
                     DIASRQLARPDTQAVLTILSPSGHEDYKKTARALIRLSEQTAKPLLVSSPFSDGITHF
                     DTPTQAIRTLSYRNTAAALKQAQLDIAPPQPCRLKTPQPQNIKKALEAADPALLAEAL
                     HLPPYRHTTHNAVQFQFGSHPLYGDILTACCNGQTTAVLPPFTTLDSRHLARFAELDG
                     TQTLDQFLHTLTVIPEYRQHILGITLNLNGGQYSSDFILKTPETHDTPKRKNTGKAAQ
                     TLEHAAAKMQSAAAYLKHKNPTAAEFLRHTSEAAAELLGSKTETGAAVPNVLAPYPAA
                     HLKTLSLKNNTTVTITPLLPEDAEAKQQFVRSLSPEARYTRFMTHTNELPAATLARLC
                     NPDYHCEAAWTARDADSNIVAVVRHSRLNRNECEFGITLAEHMRGSGLAQKMMELIIQ
                     TAAQQGYRTMSADILKTNTPMIKLAEKSGFTLKESDTEKNLYRAYLNLAADKTTEKTN
                     KNLHTDHKIT"
     gene            11561..11806
                     /gene="rpsP"
                     /locus_tag="ACFOAE_001088"
     CDS             11561..11806
                     /gene="rpsP"
                     /locus_tag="ACFOAE_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFC6884589.1"
                     /translation="MVVIRLARGGSKHRPFYNVIVTDSRSRRDGRFIERVGFYNPVAN
                     EKQERVRLNADRLNHWIAQGAQVSDSVAKLIKEQKAA"
     gene            11822..12331
                     /gene="rimM"
                     /locus_tag="ACFOAE_001089"
     CDS             11822..12331
                     /gene="rimM"
                     /locus_tag="ACFOAE_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003748672.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFC6884590.1"
                     /translation="MTDTQNRVAMGYIKGVFGIKGWLKIAANTEYSDSLLDYPEWHLV
                     KDGKTISVTLEAGKVVNSELQVKFEGINDRDLAFSLRGYTIEIPREAFAPTEEDEYYW
                     TDLVGMTVVNKDHTVLGKVSNLMETGANDVLMIDGEHGQILIPFVSQYIETVDTGSKT
                     ITADWGLDY"
     gene            12331..13080
                     /gene="trmD"
                     /locus_tag="ACFOAE_001090"
     CDS             12331..13080
                     /gene="trmD"
                     /locus_tag="ACFOAE_001090"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFC6884591.1"
                     /translation="MLIQAVTIFPEMFDSITRYGVTGRANRQGVWQFEAVNPRKFADN
                     RLGYIDDRPFGGGPGMIMMAPPLHAAIEHAKAQSSQAAKVIYLSPQGKPLTHPKAAEL
                     AELPHLILLCGRYEGIDERLLQTSVDEEISIGDFVVSGGELPAMMLMDAVLRLVPGVL
                     GDMQSAEQDSFSSGILDCPHYTKPLEFQGMAVPEVLRSGNHGLIAEWRLEQSLRRTLE
                     RRPDLLEKRVLIPKESRLLNKILQEQREIQS"
     gene            13096..13461
                     /gene="rplS"
                     /locus_tag="ACFOAE_001091"
     CDS             13096..13461
                     /gene="rplS"
                     /locus_tag="ACFOAE_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFC6884592.1"
                     /translation="MNLIQQLEQEEIARLNKEIPEFAPGDTVVVSVRVVEGTRSRLQA
                     YEGVVIARRNRGLNSNFIVRKISSGEGVERTFQLYSPTVEKIEVKRRGDVRRAKLYYL
                     RGLTGKAARIKEKLPARKG"
     gene            13481..13786
                     /locus_tag="ACFOAE_001092"
     CDS             13481..13786
                     /locus_tag="ACFOAE_001092"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884593.1"
                     /translation="MPSEPSDGISYCRNIRNGTAPKSTPLPAHPESPSEPNKIYRLNV
                     IQYHISHITINALPPSLSKPQIIMTPSLLLSGLTFRLILALIAVSLLWGVYFWAVSA"
     gene            13783..14508
                     /locus_tag="ACFOAE_001093"
     CDS             13783..14508
                     /locus_tag="ACFOAE_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010361246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFC6884594.1"
                     /translation="MSIIVENLTVSYRRRPAVHHVDITFEEHSMWAVFGPNGAGKSTF
                     LKSLMGLQPIDTGSIRLDGLTRQNIAYLPQQSDIDRSQPMTVFDLAAMGLWYEIGFFR
                     GINAVQKQRVHESLERVGMRQFAGRQIAHLSNGQFQRVLFARMLVQNAKFLLLDEPFN
                     AVDARTTYELLDVLQKCHCGGHAIIAVLHDYEQVRAYFPNTLLLAREKIAAGATETIL
                     TEPYLAQANAKMQQQESPEWCAS"
     gene            14532..15407
                     /locus_tag="ACFOAE_001094"
     CDS             14532..15407
                     /locus_tag="ACFOAE_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFC6884595.1"
                     /translation="MNLYDLLLAPFTEFDFMRYALASVFCLSLSAAPVGVFLVMRRMS
                     LIGDALSHAVLPGAAVGYMFAGLSLPAMGLGGVAAGMLMALLAGLVSRFTTLKEDANF
                     AAFYLSSLAIGVVLVSKNGSSVDLLHLLFGSVLAVDIPALQLIAAVSTLTLLTLAVIY
                     RPLVLESIDPLFLKSVGGKGGLWHVLFLVLVVMNLVSGFQALGTLMSVGLMMLPAITA
                     RLWAKHMGALILLSVLTALLCGLSGLLISYHIEIPSGPAIILCCSVLYLFSVILGKEG
                     GILTKWLKNHRHHTT"
     gene            15484..16398
                     /locus_tag="ACFOAE_001095"
     CDS             15484..16398
                     /locus_tag="ACFOAE_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003696733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFC6884596.1"
                     /translation="MKHLKLTLIAALLTASTTAAPLPVVTSFSILGDVAKQIGGERVS
                     IQSLVGANQDTHAYHMTSGDIKKIRSAKLVLLNGLGLEAADVQRAVKQSKVSYAEATK
                     GIQPLKAEEEGGHHHDHDHDHEGHHHDHGEFDPHVWNDPVLMSAYAQNVAEALIKADP
                     EGKVYYQQRLGNYQMQLKKLHSDAQAAFNAVPAAKRKVLTGHDAFSYMGKRYHIEFIA
                     PQGVSSEAEPSAKQVAAIIRQIKREGIKAVFTENIKDTRMVDRIAKETGVNVSGKLYS
                     DALGNAPADTYIGMYRHNIKALTNAMKQ"
BASE COUNT         4288 a         5296 c         3625 g         3272 t
ORIGIN      
        1 cgtctgaagc cgattcggtt ttcagacgac atcattattt gacctgacgc aaacagaaag
       61 ccttccgcgt gcttaaacac atctcttgta gtaaaatatc taaacagatt caactggaaa
      121 cggtcaggct tcttcacgcc attcccattt caaccgccgc ctgccagatt cagacggtat
      181 tcctacttga aaacaaggag cgttacaatg aaagcagcac gttttcacga taaaggcgac
      241 atccgcatcg aagacatccc cgaaccgacc gtcgcccccg gcactgtcgg catcaatgtt
      301 gcttggtgcg gcatctgcgg taccgacctg cacgaattca tggaaggccc gattttcatt
      361 ccgccttgcg gtcatccgca cccgatttct ggcgagtccg cacccgtcac gatgggacac
      421 gagttctccg gcgtggtcta tgccgtcggc gaaggcgtgg acgacatcaa agtcggccaa
      481 cacgtcgtgg tcgaacccta catcatccgc gatgacgtac cgaccggaga aggcagcaac
      541 taccacctct ccaaagatat gaactttatc ggcttgggcg gctgcggcgg cggtctgtcc
      601 gaaaaaatcg ccgtcaaacg tcgttgggtg catccgattt ccgacaaaat cccgttggat
      661 caagccgctt tgatcgaacc gctgtctgtc ggacaccacg cctatgtacg cagcggcgcg
      721 aaagctggcg acgtcgcatt ggtcggcggc gcaggtccga tcggtttgct gttggctgcc
      781 gtgttgaaag ccaaaggcat caaagtcatc atcaccgagt tgagtaaagc acgcaaagac
      841 aaagcgcgcg aatccggcgt tgccgactac atcctcgacc cgtccgaagt cgatgttgtc
      901 gaagaggtga aaaaactgac caacggcgaa ggcgtggacg tggcattcga atgtaccagc
      961 gtgaacaaag tgttggatac tttggtcgaa gcctgcaaac ctgccgccaa tttggttatc
     1021 gtatccatct ggagccaccc tgcaaccgtc aacgtccaca gcgtcgtgat gaaagagctg
     1081 gatgtgcgcg gcacgattgc ctactgtaac gaccacgccg aaaccatcaa actggtcgaa
     1141 gaaggcaaaa tcaacctcga acccttcatc acccagcgca tcaagctgga cgaactggtt
     1201 tccgaaggct tcgagcgtct gatccacaac aacgaatccg ccgttaaaat tattgtgagt
     1261 ccaaacctgt aagcaaatta catttgcaac agcacaaatg ccgtctgaaa cgctcagacg
     1321 gcattttcca acgaagcgca acaggcgtat tgcccgagag cagccgttta gcctatcatt
     1381 ccgaacaaac agaaacaaac agaaggaaaa tcatgggaga ttccgtacta tccgccatcc
     1441 aacaaaccat cacccagcga aaatctgcca atccgtccga atcttacgtc gcacagctct
     1501 tgcataaggg cgaagacaaa atcctaaaaa aagtgattga agaggcgggc gaagtgttga
     1561 tggcatccaa agacaaaaac ccgtcccacc tggtttacga agttgccgac ttatggtttc
     1621 acaccatgat tcttctgaca caccacgacc tgaaggcgga agacgtattg gacgaacttg
     1681 cgcgccgcca aggtttgtcg ggcttggccg aaaaagccgc tcgcacagaa tcttgaattt
     1741 atattaaaat ccgcactttc ccacattcaa tccgtctgac cgctgttcag acggcaacgg
     1801 agccgttatg gacaactgta ttttctgcaa aatcgccgcc aaagacattc cggcgcaaac
     1861 cgtctatgaa gacggcgaaa tggtttgttt caaagacatc aaccccgctg ctccggttca
     1921 tctgctgctg attcccaaag tccatttcga ttcgttggca cacgccgcgc ccgaacatca
     1981 gccccttttg ggaaaaatga tgctgaaagt tcccgaaatc gccaaagcgg caggactggc
     2041 agacggcttc aaaaccctga ttaacaccgg aaaaggcggc ggacaagagg tcttccacct
     2101 gcatatacac atcatgggca cacccgtata aaccgttatt tcacaatcaa cccctaatac
     2161 ttacttaagg atacatcatg ggcagttttt ctctgacgca ctggattatc gtactgatta
     2221 tcgtcgtttt gatattcggc accaaaaaac tgcgcaacgt cggcaaagac ctcggcggtg
     2281 cggttcatga cttcaaacag gggctgaacg aaggtacaga cggcaaagaa gcccaaaaag
     2341 acgatgtaat cgaacacaaa aaagacgaag acaaagcgta atttatgttt gatttcggtt
     2401 tgggcgagct ggtttttgtc ggcattatcg ccctgattgt cctcggcccc gaacgcctgc
     2461 ccgaggccgc ccgcaccgcc ggacggctca tcggcaggct gcaacgcttt gtcggcagcg
     2521 tcaaacagga atttgacact caaatcgaac tggaagaact gaggaaggca aagcaggaat
     2581 ttgaagctgc cgccgctcag gttcgagaca gcctcaaaga aaccggtacg gatatggaag
     2641 gcaatctgca cgacatttcc gacggtctga agccttggga aaaactgccc gaacagcgga
     2701 cacctgccga tttcggtgtc gatgaaaacg gcaatccgct tcccgatgcg gcaaacaccc
     2761 tatcagacgg catttccgac gttatgccgt ccgaacgttc ctacgcttcc gccgaaaccc
     2821 ttggggacag cgggcaaacc ggcagtacag ccgaacccgc ggaaaccgac caagaccgcg
     2881 catggcggga atacctgact gcttctgccg ccgcacccgt cgtacagacc gtcgaagtca
     2941 gctatatcga taccgctgtt gaaacccctg ttccgcatac cacttcgctg cgtaaacagg
     3001 caataagccg caaacgcgat ttgcgtccca aatcccgcgc caaacctaaa ttgcgcgtcc
     3061 gtaaatcata aagagggcaa tccggtgtcc gaaacacaaa acgaacaacc cgtccaaccg
     3121 cttgtcgagc atctcatcga gctgcgccgc cgcctgatgt ggacggttgt cggtatctta
     3181 gtctgctttt tcggcctaat gccgtttgcc caacaactct atacttttat cgccgacccg
     3241 ctgatggcaa acctgcccaa agacaccagc atgattgcca ccgatgtcat cgcaccattt
     3301 ttcgtgccgg tcaaagttac cctgatggcg gcatttttaa tttcgctgcc gcatacgctc
     3361 taccaaatct gggcattcgt cgcccccgca ctctaccaaa acgaaaaacg cctgattacg
     3421 ccgctcgtcc tctccagcgt cagcctgttt ttcatcggca tggcatttgc ctactttctg
     3481 gttttccccg tcattttcaa attccttgcc agcgttaccc ctgtcggtgt caatatggcg
     3541 acagacatcg acaaatacct ctccttcatc ttggggatgt ttgttgcgtt cggcacaacg
     3601 tttgaagtcc ccattgtcgt tatcctgtta accaaaattg gtgtggtaac aaccgaacag
     3661 ctcaaacgcg cccgccccta tgtgattgtc ggcgcgtttg tcattgccgc agtcatcaca
     3721 ccgcccgatg tgatttcaca aaccctgctt gccattccgc tgattctctt atacgaagca
     3781 ggtatttggt tcggacgctt tttcacgcca cgttcagaac aggatggcga catacagccg
     3841 cctgcaacaa cctgacacta tgccgtccga acctccgcct cataccgcaa cagattaagg
     3901 aatacctttg aataccctct atttaggttc aaacagcccg cgccgaatgg aaatcctgac
     3961 acagttgggc tatcaggtcg tcaagctgcc tgccgacatc aatgaaacgg tcagacagaa
     4021 cgaagaccct gcccgttacg ttcaaaggat ggcagaagaa aaaaaccgaa ccgccctgac
     4081 cctcttttgc gaaaccaacg gcacaatgcc cgatttcccc ctgattaccg ccgacacctg
     4141 cgtcgtttca gacggcatca tattgggcaa accccgctcc caagctgaag cggcaacctt
     4201 tctaaacctg ctgtcgggaa ccgggcatac cgtcctgact gctgtctgca ttcattatcg
     4261 cggcaaaacg tcaagccgcg tccaaaccaa ccgcgtcgtt ttcaagcccc tgagttcgga
     4321 agaaatttcc gcctatgtcc aaagcggcga accgatggac aaagccggcg cctacgccgt
     4381 acaaggcata ggcggcatct ttatccaatc tatcgaaggc agcttcagcg gcattatggg
     4441 gctgcccgtt tatgaaaccg tttcgatgtt acaggatttg ggataccgta ccccaccttt
     4501 catccgagcc taacccgtaa agaccgccgt gaacagacaa accgcttacc tccttacctc
     4561 tttcagcctg atcgcactga taatcctgtc cctttcctgg gaactgtgga ttgcaccgtt
     4621 gcgcccgggc ggctcgtggc tcgcgctcaa agccctcccc ctctgtctgc cgctttcagg
     4681 catcttgaaa aagaaaatct atacctacca atacagctcc atgctggttc tgatttactt
     4741 tgccgaagcc gtcatgcgcc tgttcgacgc ctatcccgca gaacagattt gcgccgcgct
     4801 ttccgcagta ttcagcatca tcttcttcat atcctgcctg tcgttcgtca aacaatacaa
     4861 ggaaacaaac aatgcccgct gaaacgaccg tatccggcgc gcaccccgcc gccaaactgc
     4921 cgatttacat cctgccctgc ttcctttgga taggcatcgt cccctttacc ttcgcgctca
     4981 aactgaaacc gtcgcccgac ttttaccacg atgccgccgc cgcagccgga ctgattgtcc
     5041 tgttgttcct cacggcagga aaaaaactgt ttgatgtcaa aatccccgcc atcagcttcc
     5101 ttctgtttgc aatggcggcg ttttggtatc ttcaggcacg cctgatgaac ctgatttacc
     5161 ccggtatgaa cgacatcgtc tcttggattt tcatcttgct cgccgtcagc gcgtgggcct
     5221 gcaagagttt ggtcgcacac ttcggacaag aacgcatcgt gaccctgttt gcctggtcgc
     5281 tgcttatcgg ctccctgctt caatcctgca tcgtcgtcat ccagtttgcc ggctgggaag
     5341 acacccccct gcttcaaaac ctcatcgttt acagcgggca aggcgtaatc ggacacatcg
     5401 gacagcgcaa caacctcgga cactacctga tgtggggcat actcgccgcc gcctacctca
     5461 acggacaacg aaaaatcccg cccgccttgg gcgcaatctg cctgattatg cagaccgccg
     5521 ttttaggttt ggtcaactcg cgcaccatct tgacctacat agccgccatc gccctcatcc
     5581 ttcccttctg gtatttccgt tcggacaaat ccaacaggcg gacgatgctc ggcatagccg
     5641 cagccgtact cctaaccgcg ctgttccaat tttccatgaa caccattctg gaaaccttta
     5701 ccggcatccg ctacgaaact gccgtcgaac gcgtcgccaa cggcggtttc acagacttgc
     5761 cgcgccaaat cgaatggaat aaagcccttg ccgccttcca gtccgccccg atattcgggc
     5821 acggctggaa cagttttgcc caacaaacct tcctcatcaa tgccgaacag cacaacatac
     5881 acgacaacct cctcagcaac ttgttcaccc attcccacaa catcgtcctc caactccttg
     5941 cagagatggg aatcagcggc acgcttctag ttgccgcaac cctgctgacg ggcattgccg
     6001 ggctgctgaa acgccccctg acccccgcat cgcttttcct aatctgcacg cttgccgtca
     6061 gtatgtgcca cagtatgctc gaatatcctt tatggtatgt ctatttcctc atccccttcg
     6121 gactgatgct cttcctgtcc cccgcagagg cttcagacgg catcgccttc aaaaaagccg
     6181 ccaatctcgg catactgacc gcctccgccg ccatattcgc aggattgctg cacttggact
     6241 ggacatacac ccggctggtt aacgcctttt cccccgccac tgacgacagt gccaaaaccc
     6301 tcaaccggaa aatcaacgag ttgcgctata tttccgcaaa cagtccgatg ctgtcctttt
     6361 atgccgactt ctccctcgta aacttcgccc tgccggaata ccccgaaacc cagacttggg
     6421 cggaagaagc aaccctcaaa tcactaaaat accgccccca ctccgccacc taccgcatcg
     6481 ccctctacct gatgcggcaa ggcaaagttg cagaagcaaa acaatggatg cgggcgacac
     6541 agtcctatta cccctacctg atgccccgat acgccgacga aatccgcaaa ctgcccgtat
     6601 gggcaccgct gctacccgaa ctgctcaaag actgcaaagc cttcgccgcc gcgcccggtc
     6661 atccggaagc aaaaccctgc aaatgacccg cgccggcgga tgcggatacc gcccgaaatg
     6721 taaagctcca tgcaagacat tgcaaaaaac agcaaaccgg tagggaaata cgctatcaaa
     6781 aaacattgca gccgtgttaa gataaaccgt caaacaatct tttcacgccc cgcccgaaac
     6841 agggtcgggg cataccctta cgaaaaggaa acaccatgag ccgcgtatta ctcgtagatg
     6901 acgatgccct gctaaccgaa ctgctgaccg aatacctgag cgccgaaggt ctgaacgtcc
     6961 gcagcgttcc cgacggggaa gcaggcgtac aggaaatcct gagcgggcag tacgatgtag
     7021 tcgtattgga ttccatgatg cccaaaatga acggcttgga tgtcttgaaa aacgtacgcg
     7081 cccgaagcac cgtccccatc atcatgctga ccgccaaagg cgacgacatc gaccgaatca
     7141 tcggcttgga aatgggcgcg gacgactatg tccccaaacc ctgcacacca cgcgaactct
     7201 tggcacgcat caatgccatc ctgcgccgcg cacaacacag cggcgaacag aacaacgcac
     7261 ccaacagcat ctccgtcagc gatgtcgtcc tgtaccccgc caaacgccag gcatccgtca
     7321 aagacatgcc gctcgaactg accagcaccg aattcaacct gctcgaagtc ctgatgcgcc
     7381 atgccggaca ggtagtcagc aaagaaaccc tgtccgtcga agcactcgac cgcaagctgg
     7441 caaaattcga ccgcagtatc gacgtacaca tctccagcat ccgccacaag ttgggcgatg
     7501 cctctctgat tcaaaccgta cgcggcttgg gctacctgtt tgtcaaaaac tgaagcaacg
     7561 ggcaaatgaa actgttccaa cgcattttcg ccacattttg cgcagttatc gtctgtgcaa
     7621 tctttgtggc gagtttttct ttttggctgg tgcagaacac ccttgccgaa aaccagttca
     7681 accaacgccg caccatcgaa accactttga tgggcagcat catttccgca ttccgggcac
     7741 gcggggacgc gggcgcgcgc gaaatcctga cggaatggaa agacagcccc gtctcatcgg
     7801 gcgtgtacgt tatacagggc gacgagaaaa aagatatcct gaaccggtat atcgacagct
     7861 acaccatcga acgcgcccgg cttttcgccg ccggacaccc gcattccaac ctcgtccata
     7921 tcgaatacga ccgcttcggc gaagaatacc tgttcttcac caaagactgg gacaaactcc
     7981 aagcccgccg cctgcccagc cccctgttga tccccggtct gccgctcgcc ccgatttggc
     8041 acgaactcat catattgtcc ttcatcatcg tcgtcggact gctgatggcg tacatcctcg
     8101 ccggcaatat cgccaaaccc atcagaatct taggcaacgg catggacagg gtggcaaacg
     8161 gagaacttga aacccgtatc tcccaacagg tcgacgaccg cgacgacgaa ttgtcccatc
     8221 ttgccatcca attcgacaaa atggtggaaa aacttgaaaa actcgttgcc aaagaacgcc
     8281 acctgctcca tcacgtctcc catgaaatgc gttctcccct tgcgcgcatg caggcaattg
     8341 tcggactgat tcaggcgcag ccccaaaaac aggagcaata tctcaaacgg ctggaaggcg
     8401 aactgacccg catggatacg ctggccgggg aactgttaac cctgtcccgt ctcgaaactt
     8461 ccaatatggc tttggaaaaa gaaagcctga aactcctgcc cttcctgggc aacctggtag
     8521 aagacaatca aagcattgcc cagaaaaacg gacaaacggt taccctgtct gccgacggaa
     8581 aaatccccga aaacacaacc atccttgcca acgaaagcta cctgtaccgc gccttcgaca
     8641 acgtcatccg caacgccgtc aactacagtc ccgaaggcag caccatcctg atcaacatcg
     8701 gacaagacca caaacactgg atcatcgacg ttaccgacaa cggccccggc gtggacgaaa
     8761 tgcagctccc gcacatcttc accgctttct accgtgcaga ctccagtgcc aacaaacccg
     8821 gaacaggact ggggcttgca ttgacccaac atattattga acagcactgc ggcaaaatca
     8881 tcgccgaaaa catcaaaccg aacggtctgc ggatgcgctt tatcctgccc aagaaaaaaa
     8941 ccggttccaa aacagaaaaa agtgcgaact gaccataata ccgtctgaac cggcttcaga
     9001 cggcattgca caaacagtta ccccaaaaca aacacacagc gggtgcatct ccaaaaatca
     9061 cgcacatacc gtccgcaaag gaatatatca tgtcggcaca aaccgatccg ggctactttt
     9121 tcatgcccaa ccacattatt ctgataggcg cgagcgaacg tccgtacagc ctgggcgaac
     9181 gcgtactcag caacctgctg agtacgccct ttcaaggaaa aatcaccccc gtaaacccgc
     9241 gccaccacac catagctggg cttcccgcct acaccagcct caacaaaatc cccggcaatg
     9301 cagacctgat tattgccgtt accctacccg acagttacga caccctcttc aaaacctgcc
     9361 gcaaaaagca gctccgacac atcatcctca tacaggactg ggacagcctg cctgccgcag
     9421 aactgcacac cgccgaaact gccatccgca aacaccacgg caacggactc aacatcaccg
     9481 cctgcaccac cgcaggcatc caactgccct cactcggact taacatcagt acccaagacg
     9541 gatacgccgc aggccatacc gccatactga ccggcaatgc cgccgtcagc cgccaaatcg
     9601 acaacatcct gaacaaactc cgtcaaggca catcccgcca catcagcctg catcccggca
     9661 tcagccccat cacttcctca gactggctca accgcttcgg acacagcctg cacaccaaaa
     9721 ccgccgtcct acaccacaac cctgaagagg atcagcgcaa actgttcagc gcaatccgcc
     9781 aatttacccg ccatacgccg ctgattctcc acatcacctg ccgcacgaca gaaaccgacc
     9841 gtgccgtact gcactgcctc gcccgacact gcaacttcct catcagtttc aacgccgacg
     9901 accttgaagc cgcactgcgc gcccaactgt ccgaccttcc acccctgtcc cgactcgaca
     9961 tcctgtccga cacgcctgcc gaatggctga acgcgcacgc gccaaaaacc ctcgccctcc
    10021 actttcccaa ccttccccac cacatccgca acggacacct gaccggcaca cccacaccct
    10081 caatctgcca cgacatcgcc tcacgtcagc ttgcccgccc cgacacccaa gccgtcctga
    10141 ccatcctcag cccctccgga cacgaggatt acaaaaaaac agcacgcgcc cttatccgcc
    10201 tgtccgaaca gaccgccaaa cccctgctcg tcagcagccc cttttcagac ggcataaccc
    10261 atttcgacac ccccactcag gcaatccgca ccctttccta ccgcaacacc gccgccgccc
    10321 tgaaacaggc acagctcgac attgcaccgc cgcaaccgtg ccgtctgaaa acaccgcaac
    10381 cccaaaacat caaaaaagcc ctcgaagccg ccgaccccgc cctgctcgcc gaagccctgc
    10441 acctcccccc ctaccggcac actacccata acgccgtcca attccaattc ggcagccacc
    10501 ccctctatgg cgacatcctg accgcatgct gcaacggaca aaccactgcc gtactcccgc
    10561 cgtttaccac gctcgacagc cgccaccttg cccgctttgc cgaactcgac ggcacacaaa
    10621 ccctcgacca gttcctgcac acactgaccg tcattcccga ataccgccaa cacattctcg
    10681 gcatcaccct caacctcaac ggcggacaat acagcagcga tttcatctta aagacacccg
    10741 aaacacacga cacgcccaaa cgcaagaaca caggcaaagc cgcccaaacc ctcgaacatg
    10801 ccgccgcaaa aatgcagagt gccgccgcat acctgaaaca caaaaacccg acagccgccg
    10861 aatttctccg ccacacaagc gaagccgccg cagaactgct cggcagcaaa accgaaaccg
    10921 gagcagccgt acccaacgta cttgccccct atcccgcagc acacctcaaa acactgtccc
    10981 taaaaaacaa cacgaccgtt accattaccc cccttttgcc cgaagacgca gaagccaaac
    11041 agcagttcgt ccgcagcctc agccccgaag cacggtacac acgcttcatg acccacacca
    11101 acgaactgcc cgcagccacg ttggcacgcc tgtgcaaccc cgactaccac tgtgaagccg
    11161 catggacggc aagggatgcc gacagcaaca tcgtcgccgt cgtccgccac agccgcctga
    11221 accgcaacga atgcgaattc ggcatcacac tggcggaaca tatgcgcggc agcggactgg
    11281 cacagaaaat gatggaactc atcatccaaa ccgccgcaca gcaaggctac cggactatga
    11341 gtgccgacat tctcaaaacc aatactccca tgatcaaact tgctgaaaaa tcaggattta
    11401 ccctcaagga atcggacacc gaaaaaaacc tgtaccgcgc atatctgaac cttgcggcag
    11461 acaaaacaac agaaaaaaca aataaaaact tgcacaccga ccacaaaata acctaaaatc
    11521 ggcagtttcc atatatccga ttttctcaaa aggactcaaa atggtagtta tccgtttggc
    11581 acgcggcggc tcgaaacacc gccctttcta caacgtcatc gttactgact cacgcagccg
    11641 ccgcgacggc cgcttcatcg aacgcgtagg cttctacaac cccgtagcca acgaaaaaca
    11701 agagcgcgtc cgcctcaacg cagaccgcct gaaccactgg attgcacaag gcgcgcaagt
    11761 cagcgactcc gttgcaaaac tgattaaaga acaaaaagcc gcctaatcca catttgccgc
    11821 catgacagac actcaaaacc gggtagccat gggctacatc aaaggcgtat tcggcataaa
    11881 aggctggttg aaaattgccg ccaacaccga atattccgac agccttttgg actaccccga
    11941 gtggcatttg gtcaaggacg gcaaaaccat cagcgttacc cttgaagccg gaaaagtcgt
    12001 caacagcgaa ctccaagtca aattcgaagg cataaacgac cgcgacttgg cattctcatt
    12061 gcgcggttac accatcgaaa taccccgtga agcattcgcc ccgacagaag aagacgaata
    12121 ctactggaca gacttggtcg gcatgaccgt cgtcaacaaa gaccataccg ttttaggcaa
    12181 ggtaagcaac ctgatggaaa ccggcgcaaa cgacgtattg atgattgacg gagaacacgg
    12241 gcagattctg attccgttcg tttcccaata tatcgaaacc gtcgataccg gcagcaagac
    12301 cattactgcc gactggggtt tggactactg atgcttatcc aggcagttac cattttcccc
    12361 gaaatgttcg acagcattac ccgctacggc gtaacgggac gcgcgaacag acagggagtc
    12421 tggcagtttg aagcagtcaa tccccgaaag tttgccgaca acagattggg ctacatcgac
    12481 gaccgcccgt tcggcggcgg cccgggaatg attatgatgg ctccgccgct tcatgcagca
    12541 atagaacacg ccaaagcaca atcttcccaa gctgcaaaag tcatttacct cagcccccaa
    12601 ggaaaaccgc tgacacaccc aaaagcggca gaactggcag aacttccgca tctgattctg
    12661 ctgtgcggac gctatgaggg aatagacgaa agactgctgc aaaccagcgt cgatgaagaa
    12721 atcagcatcg gagacttcgt tgtttccggc ggagagcttc ccgccatgat gctgatggat
    12781 gcggtattga ggctcgtacc cggcgtattg ggcgatatgc agtctgccga acaagattcg
    12841 ttctcaagcg gcattttgga ctgcccccac tacaccaaac ccttagaatt tcaaggcatg
    12901 gctgttccgg aagtattgcg ttccggcaat catggcttga tagcggaatg gcggttggaa
    12961 caatcgctgc gccgcacctt ggagcgcaga cccgatcttt tggaaaagcg cgttttaatc
    13021 ccaaaggaat cccgcctctt gaataaaatc ctacaagagc aacgggaaat ccaatcataa
    13081 tttaggaaaa aaacaatgaa cctgattcaa cagctcgagc aagaagaaat tgcccgcctg
    13141 aataaagaaa tccccgaatt cgcaccgggc gacaccgtag tcgtatccgt acgcgtcgtg
    13201 gaaggtaccc gcagccgtct gcaagcctac gaaggcgttg tcattgcacg ccgcaaccgt
    13261 ggtctgaaca gcaacttcat cgtccgcaaa atctccagcg gcgaaggcgt tgaacgtact
    13321 ttccaactgt actctccgac cgtcgaaaaa atcgaagtca aacgccgtgg cgacgtacgc
    13381 cgtgccaaac tgtactacct gcgcggtctg accggcaaag ctgcacgcat caaagaaaaa
    13441 ctgcctgcac gcaaaggttg attcaaaccc gttttcccca atgccgtctg aaccttcaga
    13501 cggcatttct tattgccgca acatccgcaa cggaacagca ccaaaaagca caccccttcc
    13561 ggcacatccc gaatccccgt ccgaaccgaa caaaatttac agactaaacg ttatacagta
    13621 tcatatcagc catataacga taaacgcttt accgccttcc ctttcaaaac cgcaaatcat
    13681 catgacacct tcccttttac tatcaggatt gaccttccgc ctcatccttg ccctgattgc
    13741 cgtatccctt ttatggggcg tttacttttg ggcagtatcc gcatgagcat cattgtcgaa
    13801 aacctgaccg tcagctaccg ccgccgacct gccgtgcacc atgtggacat tacttttgaa
    13861 gaacatagta tgtgggcggt tttcggtccc aacggcgcag ggaaatccac ctttctcaaa
    13921 tccttaatgg gattgcagcc tatcgatacg ggcagcatcc ggctggacgg attgacccgt
    13981 cagaacattg cctaccttcc ccagcagtcc gacatcgacc gctcgcagcc tatgaccgtt
    14041 ttcgacttgg cggcaatggg gctatggtat gaaatcggtt ttttcagagg aataaatgcc
    14101 gttcaaaaac aacgcgttca cgaatctttg gaacgcgtcg ggatgcggca gtttgccggc
    14161 cgccaaatcg cccacctctc aaacggacaa ttccagcgtg tcctttttgc ccgaatgctg
    14221 gttcaaaacg ccaaattcct acttctagac gaacctttca acgctgttga tgcacggacg
    14281 acctacgaac ttctcgacgt attgcagaaa tgccattgcg gcggacacgc catcatcgcc
    14341 gtactgcacg attacgaaca agtccgtgcc tactttccca ataccctgct gctcgcccgc
    14401 gaaaaaattg cggcaggcgc aaccgagacc attctgacag aaccctacct cgcccaagcc
    14461 aacgccaaaa tgcagcaaca ggaaagcccc gagtggtgcg cgtcataaat gccgtctgaa
    14521 accgaaaaac catgaacctc tacgacctgc tccttgcccc ctttacagaa ttcgacttta
    14581 tgcgctacgc cctcgcatcc gtcttctgcc tgtccctcag tgccgcaccc gtcggcgtat
    14641 tcctcgtcat gcgccgtatg agcctgatag gcgacgcatt gagccacgcc gtcctgcccg
    14701 gtgccgccgt cggctacatg tttgccggct tgagcctgcc cgccatgggt ttgggcggcg
    14761 tagccgcagg catgctgatg gcactgcttg ccggacttgt tagccgcttc accaccctga
    14821 aagaagatgc caactttgcc gccttttatc tcagcagcct cgccataggc gtagtcctcg
    14881 tcagcaaaaa cggcagcagc gtcgatctgc tgcatctgct tttcggctct gtacttgccg
    14941 tcgatattcc tgccctgcag ctcatcgccg ccgtatccac cctcacactg cttacccttg
    15001 ccgtcatcta ccgcccgctc gtactcgaaa gcatcgaccc cctgtttctc aaatctgtcg
    15061 gcggcaaagg cgggctttgg cacgtcctct ttctcgtcct ggtcgtcatg aacctcgtat
    15121 ccggctttca agccctcggc acactcatgt ccgtcggact catgatgctg ccagccatta
    15181 ccgcccgcct gtgggcgaag cacatgggcg cactcatcct cctatccgtt ctgacagccc
    15241 tgctgtgcgg cttgagcggg ctgctcattt cctaccacat cgaaatccct tccggccccg
    15301 ccatcatcct ctgttgcagc gtcctttatc tcttttccgt catactcggc aaagaaggcg
    15361 gcattctgac caaatggctc aaaaaccacc gccaccacac cacctgaccc cgcaagccgc
    15421 ttgaacaaac aggcggcttg ttttaccata acagatgtta cgttatatca caggagaaca
    15481 gttatgaaac acctcaaact cacccttatt gccgcattgc tgaccgcctc cacaactgcc
    15541 gcccccctgc cggttgtaac cagcttcagc attttaggcg acgtagccaa acaaatcggc
    15601 ggagagcgcg tatccataca aagtttggtc ggagccaacc aagatacgca cgcctatcat
    15661 atgaccagtg gcgacattaa aaaaatccgc agtgcaaaac tcgtcctgct caacggctta
    15721 ggacttgaag ctgccgatgt acaacgtgcc gtcaaacaga gcaaagtatc ctatgccgaa
    15781 gcgaccaaag gcatccaacc cctcaaagcc gaagaagaag gcggacacca tcatgaccac
    15841 gatcatgacc acgaaggaca ccaccatgac cacggcgaat tcgaccccca cgtctggaac
    15901 gaccccgtcc ttatgtccgc ctatgcccaa aacgtcgccg aagccctgat aaaggccgac
    15961 cccgaaggca aagtttatta tcaacaacgt ttgggcaact accaaatgca gctcaaaaaa
    16021 ctgcacagcg acgcacaagc cgcatttaac gccgtccctg ccgccaaacg caaagtcctg
    16081 accgggcacg atgccttttc ctacatgggc aaacgttacc atatcgaatt catcgccccg
    16141 caaggtgtga gcagcgaagc cgagccttca gccaaacaag tcgccgccat catccgacaa
    16201 atcaaacgcg aaggcatcaa agccgtcttt accgaaaata tcaaagacac ccgcatggtt
    16261 gaccgtatcg ccaaagaaac cggtgtcaac gtcagcggca aactgtattc cgacgcactc
    16321 ggcaacgcgc ccgcagacac ctacatcgga atgtaccgcc acaacatcaa agccttgacc
    16381 aacgcgatga agcaataaaa ccgtttgatt ggtttgaatt tgaaaaggca aaaggccgtc
    16441 tgaaaattat agtggattaa caaaaatcag gacaaggcga c
//
LOCUS       DAXIDM010000041        16336 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000041 DAXIDM010000000
VERSION     DAXIDM010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16336
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.041"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(684..1046)
                     /locus_tag="ACFOAE_001096"
     CDS             complement(684..1046)
                     /locus_tag="ACFOAE_001096"
                     /inference="COORDINATES: protein motif:HMM:NF018933.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HFC6884597.1"
                     /translation="MKAARRQLYYTFANRIAEQSRIICIKKLNLLNLQCIQIEVNKLH
                     QKIVAPSPLLHTLKEGAAKNGVHIEEIKANATSQSCYSCGRLNKRIGVAATRTNMVCE
                     GFGRHYDTDENASSNIRK"
     gene            1466..2830
                     /locus_tag="ACFOAE_001097"
     CDS             1466..2830
                     /locus_tag="ACFOAE_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFC6884598.1"
                     /translation="MQHLTERMTQIAKLLNSSPNNPDIDIPDFLTEIKDYSEFSVTDE
                     NGTYLHWDKFRRIHTEDTRMKWRAVKESRKKIQKPIDFPFEHQFWFCIPDSLQARLHL
                     IDKSCSSSIGTSSLSGFGRSEQNRFLLKSLIMEEAITSAQLEGAATTRKVAKDMLKSQ
                     RKPKTKDEIMIVNNYHLMKKAVELKNTPLSVEMILDLHRIATSNAIENKAEPGQFRQD
                     DEIFIADINGNSLYQPPPHGQVHTLMEEVCAFANNTYDGVENPFIHPVVQAIILHFLI
                     GYIHPFGDGNGRTARALFYWFMLKNGYWLFEYISISRLLKNAPAQYAKSYLYAETDDL
                     DLTYFIYYQCDIIKRAVADLEHYISDKQKHQQEFKAAIAQYTEKIGKLNQRQIGILQK
                     AVEESGKIFTAQEIANQYGISLNTARSDLSKLGEYRFLVPFKSGNALEYVAPQDLLER
                     LEKK"
     gene            3191..3697
                     /locus_tag="ACFOAE_001098"
     CDS             3191..3697
                     /locus_tag="ACFOAE_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884599.1"
                     /translation="METTFALLNFKESLCYIYPPTEPDRYVSSIVALNVHSPNGTGDW
                     HSAKALSDRAYPEKFYIYGENQERNTNHLLGDNGIIDGTDRLNKMGYFPENIPVWLAD
                     HPRACVDYLYTAVLQTGSIGRVILDDWFPSDEDKQSVYDLLNQIEPHLNTQEWENLQL
                     WKRKNPIM"
     gene            3824..5113
                     /locus_tag="ACFOAE_001099"
     CDS             3824..5113
                     /locus_tag="ACFOAE_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family
                     toxin"
                     /protein_id="HFC6884600.1"
                     /translation="MMKSILTVSGNRMRKPRITYLDVWANDERIGTLEKGAMYRFTYD
                     NPNSSLLGLHYQDRSKVYISNNMPHIFAQYFPEGFLAAHITSKYAFHDAPFEDNEMLR
                     LAILGREALGRIHVRCNDPLFNEWIDGLEMKNPRILTERDLLGINARQVFQQYMAEIF
                     HHGRFVSVSGIQQKMSLDAISRNTKQTASYIAKGFDASEYPCLAANEFLCMQTIKQAG
                     IAVAQTSLSEDSSVLLVRRFDVSEQGYFLGMEDFTSLRQYSAEDKYKGSYAAIAQIIR
                     QISGRPDEDLIHFFNQLAASCILKNGDAHLKNFSVLYHDEYDVRLAPAYDVLDTSIYR
                     VGTQGIFDAYDDTLALNLTNHGKKTYPSKNTLLDFAEKYCDLGREDASFMIDTIVQAK
                     EQVLVKYSDVLRENEWLAQKWHFIPDENEEGLPFTFR"
     gene            complement(5450..7237)
                     /locus_tag="ACFOAE_001100"
     CDS             complement(5450..7237)
                     /locus_tag="ACFOAE_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046930 - pore complex [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA];
                     GO_process: GO:0006811 - monoatomic ion transport
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HFC6884601.1"
                     /translation="MKLPLSYLPNIRFLSWCCLLAGIIAPATLLASPNPAEIRMQQDI
                     QQRQREEQLRQTMQPESDVRLHQKNTGETVNQLMGDDSSQPCFAINEVVLEGEHHDRF
                     QFALKRALRETGFQAGKCLHAGNINQIMSLAQNALIGRGYTTTRILAAPQDLNSGKLQ
                     LTLIPSYLRSIRIDRSNDDQTHAGRIAAFQNKFPTRSNDLLNLRDLEQGLENLKRLPT
                     AEADLQIVPVEGEPNQSDVVVQWRQRLLPYRVSVGMDNSGSEATGKYQGNITFSADNP
                     FGLSDMFYVNYGRSIGGTPDEESFDGHRKEGGSNNYAVHYSAPFGKWTWAFNHNGYRY
                     HQAVSGLSEVYDYNGKSYNTDFGFNRLLYRDAKRKTYLGVKLWTRETKSYIDDAELTV
                     QRRKTAGWLAELSHKEYIGRSTADFKLKYKRGTGMKDALRAPEEAFGEGTSRMKIWTA
                     SADVNTPFQIGKQLFAYDTSVHAQWNKTPLTSQDKLAIGGHHTVRGFDGEMSLSAERG
                     WYWRNDLSWQFKPGHQLYLGADVGHVSGQSAKWLLGQTLAGTAIGIRGQIKLGGNLHY
                     DIFTGRALKKPEFFQSRKWASGFQVGYTF"
     gene            complement(7292..7750)
                     /locus_tag="ACFOAE_001101"
     CDS             complement(7292..7750)
                     /locus_tag="ACFOAE_001101"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009404 - toxin metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein-lysine palmitoyltransferase"
                     /protein_id="HFC6884602.1"
                     /translation="MPITPPLNIISPKLYLNEQWNESEALGAITWLWYQSPTHRQVPI
                     VEMMTYILPVLKNGQFALFCKGTQPIGYISWAHFDEVAQAHYLESDRHLRDNSDWNCG
                     DNIWLIQWFAPLGHSHQMRSAVRQLFPSTTVRALYHKGSDKGLRILTFKT"
     gene            complement(7914..8228)
                     /locus_tag="ACFOAE_001102"
     CDS             complement(7914..8228)
                     /locus_tag="ACFOAE_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884603.1"
                     /translation="MKKILSNLMLISFCSTMLTACPFWGSCANWNCSELNPRWVKSVH
                     NCRSNNYKVVLSAIGSKFNYQSTSQVQDSDIGQHISGQCTYYDGRYDVRKDKQYGHLF
                     VQ"
     gene            complement(8209..15741)
                     /locus_tag="ACFOAE_001103"
     CDS             complement(8209..15741)
                     /locus_tag="ACFOAE_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin repeat-containing protein"
                     /protein_id="HFC6884604.1"
                     /translation="MNKTLYRVIFNRKRGAVVAVAETTKREGKSCADSDSGSAHVKSV
                     PFGTTHAPVCRSNIFSFSLLGFSLCLAVGTANIAFADGIIADKAAPKTQQATILQTGN
                     GIPQVNIQTPTSAGVSVNQYTQFDVGNRGAILNNSRSNTQTQLGGWIQGNLWLARGEA
                     RVVVNQINSSHSSQMNGYIEVGGRRAEVVIANPAGIAVNGGGFINASRATLTTGQPQY
                     QTGALTGFQVRSGHIAITGQGLDARDTDFTQILSHAVKIDGPVWGKDVRVSAGKNDVS
                     ADGSIQSSHSPATNINSDNSLYAIDTGALGGMYAGKITLISTDRDASVRNQGQWFASA
                     GNVAIDANGRLVNSGTMAAANVQDMNNTAEHKVNIRSQAFENSGTAVSQQGTQIHSQS
                     IQNTGTLLSSGEILIHNSGSLKNETSGTIEAARLAIDTDTLNNQGKLSQTGSQKLHID
                     AQGKMDNRGRMGLQDTAPTASNGSSNQTGNSYNASSHSSTTTPTTATGTGTATVSISN
                     ITAPTFADGIIRTHGALDNSGSIIANGQTDVSAQQGLNNAGQIDIHQLNAKGSAFDNH
                     NGTIISDAVHIQAGSLNNQNGNITTRQQLEIETDQLDNAHGKLLSAEIADLAVSGSLN
                     NQNGEIATNQQLIIHDGQQSTAVIDNTNGTIQSDRDVAIQAKSLSNNGTLAADNKLDI
                     ALQDDFYVERNIVAGNELSLSTRGSLKNSHTLQAGKRIRIKANNLDNAAQGNIQSGGT
                     TDIGTQHNLTNRGLIDGQQTKIQAGQVNNIGTGRIYGDNIAIAATRLDNQDENGTGAA
                     IAARENLNLGIGQLNNRENSLIYSGNDMAVGGALDTNSQATGKAQSIRNASATIEAAG
                     KMRLGVEKLHNTNEHLKTQLVETGREHIVDYEAFGRHELLREGTQHELGWSVYNDESD
                     HLRTPDGAAHENWHKYDYEKVTQKTQVTQTAPAKIISGNDLTIDGKEVFNTDSQIIAG
                     GDLLVQTEKDGLHNEQTFGEKKVFSENGKLHSYWREKHKGRDSTGHSEQNYTLPEEIT
                     RNISLGSFAYESHRKALSHHAPSQGTELPQSNGISLPYTSNSFTPLPSSSLYIINPVN
                     KGYLVETDPRFANYRQWLGSDYMLDSLKLDPNNLHKRLGDGYYEQRLINEQIAELTGH
                     RRLDGYQNDEEQFKALMDNGATAARSMNLSVGIALSAEQVAQLTSDIVWLVQKEVKLP
                     DGGTQTVLVPQVYVRVKNGDIDGKGALLSGSNTQINVSGSLKNSGTIAGRNALIINTD
                     TLDNIGGRIHAQKSAVTATQDINNIGGILSVEQTLLLNAGNNINSQSTAASSQNTQGS
                     STYLDRMAGIYITGKEKGVLAAQAGKDINIIAGQISNQSEQGQTRLQAGRDINLDTVQ
                     TSKHQATHFDADNHVIRGSTNEVGSSIQTKGDVTLLSGNNLNAKAAEVSSANGTLAVS
                     AKNDINISAGINTTHVDDASKHTGRSGGGNKLIITDKAQSHNETAQSSTFEGKQVVLQ
                     AGNDANILGSNVISDNGTRIQAGNHVRIGTTQTQSQSETYHQTQKSGLMSAGIGFTIG
                     SKTNTQENQSQSNEHTGSTVGSLKGDTTIVAGKHYEQIGSTVSSPEGNNIIHAQSIDI
                     QAAHNKLNSNTTQTYEQKGLTVAFSSPVTDLAQQAIAVAQSSKQVGQSKNGRVNAMAA
                     ANAGWQAYQTGKSAQNLANGTTNAKQVSISITYGEQQNRQTTQVQASQAQASQIQAGG
                     KTTLIATGAAEQSNINIAGSDIAGKAGTILIADNDITLQSAEQSNTERSQNKSTGWNA
                     GAAVSFGQGGWSLGVTAGGNVGKGYGNGDSVTHRHSHIGDKGSQTLIQSGGDTTIKGA
                     QVRGKGVQVNAKNLSIQSVQDSETYQSKQQNASAQVTVGYGFSASGDYSQSKIRANHA
                     SVTEQSGIYAGEDGYQIKVGNHTDLKGGIITSTPSAEDKGKNRFQTATLTHSDIKNHS
                     QYKGESFGLGASASISGKTLGQGAQNKPQNKHLTSVADKNGASSSVGYGSDSDSQSSI
                     TKSGINTQNIQITDEAAQIRLTGKTAAQTKADIGTNVTTDTAERHSGSLKNTFNREAV
                     QNELDLQREVTQEFDKTRQGVKQELYAVVDSKRAQATQERLKNGGYDNDKSRALNKEA
                     NELDEKIRWLDAGLGLVWGAGSSDMAWSMFATTQADRAVRSATAPKEMWFHKKIIDEK
                     TGKVSFDTRQIWSLNDLSKEELASIQDTNGKVITVSNPGIFNNREDSLSNAAKQNRNS
                     TNGSGVIAVMNPPTGKYKSDSNNKIKDFLWLGSSLVSELMYVGYDQLNNKVFQGYLPK
                     TNSEKLNQDIYREVQKMGNGWSVDTSNHSRGGITASVSLKDWVNNQKQNGIAPIRKAR
                     FYGTATNVQNDYADVLQKNGYTYTGADGKTYNSGSYSIVHDKDFVGNKWIPFLLGTND
                     TTQGTCKGFCYSHSSYFAEVPEQYKRDKNGNFVTDNEGNKIETKDWDSYTKIWGIPKK
                     GTDGKDINHAIPKLVNPNKPNGEKYEENPF"
     gene            15897..16049
                     /locus_tag="ACFOAE_001104"
                     /pseudo
     CDS             15897..16049
                     /locus_tag="ACFOAE_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4163 a         3491 c         3584 g         5098 t
ORIGIN      
        1 acaggtatta gatactgcct tttcttacaa gagtgatggt aggatggttc tcttcaagtc
       61 aatcaaacag gaaagtattt cttttctatc tgaagatttg aaaaaggact ggatgttaca
      121 caaggttaaa actgggaaaa agatggatat ggttcagatg aaatgctgag cgtaccctgt
      181 gtctatttgg aaatgatgtc gcggaaaacg ggagtcccct actccagtat tctttaaagt
      241 ctaagtagaa gacttcttcg tcggtctttt tttgttgttt ggtttgcatg gagtaaaact
      301 gtacaactgt tgaagcataa aaccagcaag aaggtaaaaa agaaagaagc agttctttgg
      361 attttagata ttaccgcaat tagtttcctt tcctaaaatt tgtttaaatt atttgcaata
      421 ttaatataaa cgagatatta atgatgagaa atcaaaaagg catactaaat acaatttgta
      481 caaaataatt gcagtattta aaaatgttga ttcgtatatg aaaagttaaa aatgccaaaa
      541 tgtacagttg ctaaactgta aaactgccaa agcaacaaaa cataaaaagg aatgcaggga
      601 tgcaatcact acatcttttt attccgtaag catttatgac tttacggtca actgctactc
      661 tatgtttcca gcttttcagc tccctatttt cgaatattgg acgaggcatt ttcatcagtg
      721 tcgtaatgcc ggccgaaacc ctcacaaacc atattggttc ttgtggcagc aacacctatc
      781 cgtttgttca agcggccaca agagtaacat gattggctgg tggcattggc tttaatctct
      841 tcgatatgaa ctccattttt agctgcacct tctttcagcg tatgcaacag tggggatggg
      901 gcaactatct tctggtggag tttgttgact tcaatctgta tgcactgtag gttgagcaga
      961 ttcagttttt tgatacagat tatccggctt tgttcggcaa ttctgttggc gaacgtatag
     1021 tagagctgtc gtcttgccgc tttcaatttg cggtaggtat tttaccattc catgcgtagc
     1081 cgctcggtac gtttgagcca aatggtatct tcgccatttg taccaattgg tttttacatt
     1141 cggctgtgtt ttagtaattt attaatttca attatttgca agggaaaaga caattgtttc
     1201 cggttaggaa taaacctatc ctattgaata tattgaagcc aagtacgtct atcaacacta
     1261 tattaaaaca cagccttttt taatatagta gacacaatct ttccctattt atgaaggtga
     1321 tcgcttcttt cagattcgta ttttaatact ttctatttct agaaaatttg actaaaataa
     1381 ctcaattata aaaaattgcg cgattttggt atttatcatg aaaatttcca gacctccgga
     1441 atttaccctg ttgcaacagg aatatatgca gcatctcact gaaagaatga cgcaaattgc
     1501 caagctgctg aattcttccc caaacaatcc tgatatagac attcccgatt ttcttactga
     1561 aatcaaagat tattcagaat tttccgtgac agatgaaaat ggaacctacc tgcattggga
     1621 caaattccgc cggattcaca cggaagatac gcggatgaaa tggcgcgccg ttaaggaaag
     1681 ccgcaaaaaa atccaaaaac caattgattt cccgtttgaa catcagtttt ggttctgcat
     1741 tcccgactct ttgcaggcac ggcttcattt gattgacaaa agctgcagca gttctatcgg
     1801 cacgtctagc ttgagtggtt tcggcagaag cgagcaaaac agattcttgc tcaagtctct
     1861 gattatggaa gaagcgatta catccgccca actggaaggt gcggctacca cgcgtaaagt
     1921 ggccaaggat atgctcaaat cgcagcgtaa acccaaaaca aaagacgaaa tcatgatagt
     1981 gaacaactat cacttgatga aaaaagcggt agaattgaaa aatacgccgt taagtgttga
     2041 aatgattttg gatttgcacc gcattgctac cagcaacgct attgaaaaca aggccgagcc
     2101 cggacaattc aggcaggatg acgaaatctt tatcgccgat atcaatggta acagcctgta
     2161 tcaaccaccg ccgcacggac aggttcatac gctgatggaa gaggtgtgtg cgtttgccaa
     2221 taatacctat gacggcgtgg aaaatccgtt tatccatccg gttgtccaag ctattatcct
     2281 gcatttcctc atcggctaca tccacccatt tggtgatggc aacgggcgga cagcgcgggc
     2341 tttgttctat tggtttatgc tcaaaaacgg ctactggcta tttgaataca tatccatcag
     2401 ccgtcttctg aaaaacgctc ctgcccaata cgccaaatcc tatttgtatg cggaaactga
     2461 cgatttagat ttaacctatt tcatctatta ccaatgcgat attatcaagc gggcggttgc
     2521 tgatttggag cactacattt ctgacaaaca aaaacaccaa caggaattca aagcagcgat
     2581 tgcccaatat actgaaaaga taggaaagtt gaaccaacgg caaattggta tcctgcaaaa
     2641 agcagtggaa gaaagcggaa aaatctttac tgcacaagaa attgccaacc aatacggcat
     2701 ctccctgaat actgcccgta gcgatttgag caaactggga gaatatagat tcctagtgcc
     2761 gttcaaatca ggaaatgctt tagagtatgt tgctcctcag gatttattgg aaaggttaga
     2821 aaaaaaatag tttgctagcc taaaatgcag ctttaaccga gtcaaaatca atacagtccg
     2881 caccttcaaa aagaagctgc ggactgcttg ctttttgctc tacaaatgat ctttgtagct
     2941 gatttaacca agattgtagc aattttgctt tccgagcaag cagggttaga aaattcgata
     3001 cttttaatta ttggctgtgt tttaatatga tgttgatagg cgtgtttggc tttaaggtat
     3061 tcaacaggat aggtttattc ctaaccggaa aataattgtc ttttcccttg caagtaattg
     3121 aaatcaacag attactaaaa cacagcctta cattattggg gtgactatcc tgtaaaatat
     3181 gtcctaaaac gtggaaacca cttttgctct gctaaatttt aaggaatctt tatgttacat
     3241 atacccccca acggaacctg atcgatatgt tagcagtatt gtagccttaa acgtgcatag
     3301 tcctaacggt acaggcgact ggcatagtgc aaaggcattg agtgatcggg cttaccctga
     3361 aaaattttat atttacggtg aaaatcaaga gcgaaatacc aatcatctat taggtgacaa
     3421 tggcattatt gatgggacgg atcgactgaa caaaatgggt tatttccctg aaaacatccc
     3481 agtttggctc gcagatcacc cccgtgcttg cgtggattat ctttacacag cagtgttaca
     3541 aactggctca atcggtcggg tgattttaga tgattggttt ccaagcgatg aagacaagca
     3601 atcagtttat gacttactta accaaatcga accgcacttg aatactcaag aatgggagaa
     3661 tttacagcta tggaaacgca aaaacccaat aatgtaatgc taaccgaacg agataaaagg
     3721 cacgagaagc ggtattactg aatttcatcc gcaatacgcc atgtacaatt aaatcagcag
     3781 atgtgtctaa acgtaccgct gttcccgttt gaaagaaatt ttcatgatga agtctatcct
     3841 caccgtatcc ggaaatcgta tgcgtaaacc cagaatcacc tatttggatg tttgggcaaa
     3901 cgatgaaaga atcggtactt tggaaaaggg ggccatgtat cggttcacat acgacaatcc
     3961 caattcttcg ttgctgggcc tgcattatca agacagaagc aaggtatata tcagcaacaa
     4021 catgccacat atctttgcac agtattttcc ggaaggcttt ttggccgcac acatcacaag
     4081 caaatatgct tttcatgatg cgccttttga agacaatgag atgctgcgct tggcaattct
     4141 gggcagagag gctttgggtc ggatacatgt gcgctgtaat gacccgcttt ttaatgaatg
     4201 gattgacggg ttggagatga aaaatccaag aatattgact gaacgggatt tgctgggcat
     4261 aaatgcccga caggtttttc agcaatatat ggcagaaatc ttccatcacg gccgtttcgt
     4321 cagtgtatcc gggatacagc agaagatgtc cttagatgcc atcagcagaa ataccaagca
     4381 aactgcctca tatattgcca aaggttttga tgcatccgaa tatccttgct tggctgccaa
     4441 tgaattttta tgcatgcaga ccatcaaaca agccggcatt gccgttgcac agaccagcct
     4501 gtcggaagat tcatcagtct tattggtacg tcggtttgat gtcagtgaac aggggtattt
     4561 cttaggcatg gaagacttta ccagtctgcg tcagtattca gcagaagata agtataaagg
     4621 cagttatgcg gctattgcac agattatccg acagatatcc ggcagacccg atgaagattt
     4681 aatccatttc tttaaccaac ttgccgccag ttgcatattg aaaaacggcg atgcacacct
     4741 caaaaatttt tcagtactct atcatgacga atacgatgta cgtcttgcac ctgcctatga
     4801 tgtattggat acatcaatat acagggttgg aacacaagga atttttgatg cttatgacga
     4861 tacgctggca ttaaacctga ctaaccacgg taagaaaaca tatccttcca agaatacatt
     4921 gttggatttt gctgagaaat attgcgattt gggaagagaa gatgcatcct ttatgataga
     4981 tacaatcgtt caagctaaag aacaggttct tgttaaatac tcggatgtat tgcgtgagaa
     5041 tgaatggttg gcgcagaagt ggcattttat cccggatgaa aatgaagaag gtctaccgtt
     5101 tacattccgg tagctgccgg gtttgaaccg gctgtcagag atggccggtc gactttcacc
     5161 ctgaaaatca cttcatctta tggtgtttga aaccgagaaa ttagaagaat cgtattcggt
     5221 aggagatata ctaggaagat tggaaaactg gtaaatcatt ctattgattg agttggcggc
     5281 ctatatgttt aatgtaggca aacgagaagg aatcatgtat ttcatgattc cttcttaaat
     5341 tcctgtgtca atctaatatc aaaacacagc catctcttac cataatcatg ataggtgttt
     5401 tattatgaaa agctatatct ataattaccg ttgatttgac tatgccgttt taaaacgtat
     5461 agcctacctg aaaaccgctt gcccatttcc ttgattggaa aaattcgggc tttttcaatg
     5521 cgcggccggt aaatatatcg taatgcaggt tgccgccaag ctttatctgc ccgcgtatcc
     5581 caattgctgt gccggctaga gtttggccca ataaccattt ggcggattgt cctgaaacat
     5641 gtcctacatc agccccaaga taaagctgat ggcctggttt aaattgccag ctcaaatcgt
     5701 tgcgccaata ccatccccgc tcggcagaca aactcatttc accgtcgaag ccacgtacgg
     5761 tgtggtgtcc gccgatagcc agtttgtctt gcgatgttag cggggttttg ttccattgtg
     5821 catgaacgga tgtgtcatag gcaaatagct gtttaccgat ttgaaaagga gtatttacat
     5881 cagccgatgc cgtccaaatt ttcatacgtg acgtgccttc tccaaaggct tcttcaggcg
     5941 cgcgcagagc atctttcatg ccggtgccgc gtttatattt caacttaaaa tctgccgtac
     6001 tgcggccgat atattctttg tgggaaagtt ctgccaacca acccgcagtt ttacgccgtt
     6061 gtacagtcag ttcggcatca tcaatgtaac tttttgtttc cctcgtccac agttttacac
     6121 caagataggt tttgcgtttg gcatcacgat acaacaggcg gttgaagccg aaatcagtat
     6181 tgtaactttt tccattatag tcatagactt ccgataatcc ggaaaccgcc tgatggtaac
     6241 ggtagccatt gtgattgaat gcccatgtcc atttaccgaa aggggctgaa taatgtacgg
     6301 cgtaattgtt tgatccgcct tctttgcgat ggccgtcaaa actttcctcg tcgggcgtac
     6361 cgccaattga acgtccataa tttacataga acatatcact cagtccaaaa ggattgtcgg
     6421 cagagaaagt gatatttcct tggtattttc ctgtcgcctc actacccgaa ttatccatcc
     6481 ccacactcac acggtagggc agcagacgtt gccgccattg caccacgaca tcactttggt
     6541 ttggttctcc ctctacggga acgatttgga gatcggcttc cgcagtcggg agacgtttga
     6601 gattttccag tccttgttcc aaatcacgca gattcaacag atcgttcgag cgggtgggaa
     6661 atttgttctg gaatgctgca atacgtcctg catgggtttg atcatcgtta gaccgatcga
     6721 ttcgtatgga gcgcagatag ctcggtatca gggttaattg aagcttgcca ctattcaaat
     6781 cctgtggcgc agccaagata cgggtcgtgg tatatcccct gccgatcaaa gcattttgtg
     6841 ctaaggacat gatttgatta atgttgcccg catgcagaca cttgccagcc tgaaaacccg
     6901 tttcgcgcaa ggcacgtttt agggcaaact gaaaccgatc atggtgttca ccttccaaca
     6961 ccacttcgtt aatggcaaaa cacggttggc tgctgtcatc gcccatcaac tgattaaccg
     7021 tttcccccgt gtttttttga tgcaaacgca catcgctttc aggctgcatg gtttggcgca
     7081 actgctcttc gcgttggcgt tgctgaatat cttgctgcat acggatttcg gcagggttgg
     7141 gggaagccaa caaagtagca ggagcgatga tacctgccaa taagcagcac caagacaaaa
     7201 agcgaatatt aggcaaatag gataaaggaa gtttcatggc atggtcgcaa aatcaataaa
     7261 atcatcaatg ggcattcaat acacgattgc atcaagtttt aaaagttaaa attctcaaac
     7321 ccttatcgct ccctttatga tacaaggcgc gtactgtcgt actaggaaat aactggcgca
     7381 cagctgagcg catttgatga ctgtgtccca atggcgcaaa ccattgaatc agccaaatat
     7441 tgtcgccaca gttccaatcg ctgttgtcgc gcaaatggcg gtcagattct aaataatgcg
     7501 cctgcgccac ttcatcaaaa tgagcccatg agatataacc gattggttgg gtacccttgc
     7561 aaaacaaagc gaactgcccg ttttttaaca caggcaatat atacgtcatc atctccacaa
     7621 taggtacttg gcgatgcgta ggcgactgat accatagcca agtgatggca ccgagtgctt
     7681 cgctttcgtt ccattgttca ttgaggtaga gtttagggga gatgatgttt aagggtggag
     7741 tgatgggcat attttaagtt agggttggtg ttggttaaaa caaaaaatgg tttcagcctg
     7801 aaatgaaata tctcacgtta aaacatagct ttagcatacg agactgaatt gtggggcaat
     7861 aagcaacgac cctaccattc aacaattctc gttaattgca caggttacgc tggttattgc
     7921 acaaacaaat gaccatactg cttatctttg cgaacatcgt atctgccatc atagtaagta
     7981 cattgtccag aaatatgttg cccaatgtca ctatcttgaa cttggcttgt tgattgatag
     8041 ttaaatttac ttcctattgc cgataacaca actttatagt tatttgatcg acaattatga
     8101 actgatttca cccagcgtgg attgagttcg gaacaattcc agtttgcaca actgccccaa
     8161 aaagggcaag ctgttagcat tgttgagcag aatgatatta gcattaaatt agaaaggatt
     8221 ttcttcatac ttttctccat ttggcttgtt tggattgact aatttgggaa tagcgtgatt
     8281 tatgtctttt ccatcagtac cttttttagg aattccccat atttttgtgt aactgtccca
     8341 gtctttcgtt tcaattttat tcccttcatt atcagtaaca aaatttccat ttttgtctcg
     8401 cttatactgt tcaggcactt ccgcaaaata tgaactgtgc gaataacaaa accccttaca
     8461 tgtaccttgt gtggtgtcat tggttcctaa taagaaaggt atccatttgt tccccacaaa
     8521 atctttatca tgcacgattg agtaggatcc gctgttataa gttttgccgt ctgcacccgt
     8581 ataggtatag ccgtttttct gtaaaacatc ggcgtaatca ttctgcacat ttgtggctgt
     8641 accatagaaa cgtgcttttc tgattggggc aatgccattt tgtttttgat tgtttaccca
     8701 atcttttaag gaaacgcttg ctgtaattcc cccacgactg tgattactgg tatcaaccga
     8761 ccagccgtta cccatttttt gaacctctcg ataaatatct tgattcagtt tttctgaatt
     8821 ggttttgggt aaatagcctt ggaacacttt attatttaat tggtcgtaac cgacatacat
     8881 cagttcagaa acaagacttg aaccgagcca taaaaaatct tttattttgt tattagaatc
     8941 agatttatat ttccctgttg gaggattcat aactgcaata acaccactac cgtttgtact
     9001 attacgattt tgttttgctg cgttgcttaa tgaatcttct cgattattga aaataccagg
     9061 attagacaca gtaataactt tgccatttgt gtcttgaatg cttgccagtt cttccttgct
     9121 taaatcattc aatgaccaaa tttgtctggt atcaaaggat actttacctg ttttttcatc
     9181 tattatcttc ttatggaacc acatttcttt aggtgcagtt gcagacctta ccgctctatc
     9241 ggcttgggtt gtggcaaaca tactccaagc catatcagaa ctccctgcgc cccaaacgag
     9301 tcctaatccc gcatcaagcc aacgaatttt ttcatctaat tcattagctt ccttatttaa
     9361 tgctctagat ttatcattgt catatccacc atttttgagt ctctcttgtg tggcttgcgc
     9421 tcgtttgcta tctactactg cataaagttc ttgtttcact ccttgtctag ttttatcaaa
     9481 ctcttgggtt acttcccttt gcaaatccag ctcgttttgc accgcttctc tgttgaaggt
     9541 gttcttcaag ctgcccgaat gtcgttcggc ggtgtctgtg gttacgtttg taccaatatc
     9601 ggctttggtt tgtgccgctg ttttgcctgt cagcctgatt tgtgcggctt cgtcggtgat
     9661 ttgaatgttt tgggtgttga tgccgctttt cgtgatgctg ctttgactgt cgctgtcgct
     9721 gccataaccc actgatgaac ttgcgccgtt tttatcggct acgcttgtca ggtgtttgtt
     9781 ttgaggctta ttttgtgcgc cctgtcccag tgttttgccg cttatggacg cacttgcgcc
     9841 caatccaaaa ctttcgcctt tgtattggct gtggtttttg atgtcgctat gggtgagggt
     9901 ggccgtctga aagcggtttt tacccttgtc ttctgcgctt ggggtactgg tgatgatgcc
     9961 gcctttgagg tctgtatggt ttccgacctt gatttgatag ccgtcttctc cggcataaat
    10021 accgctttgc tcggttaccg aagcatgatt ggctcggatt ttgctttggc tgtaatcgcc
    10081 actggcactg aagccataac cgacggtcac ttgtgcactg gcgttttgtt gtttgctttg
    10141 ataggtttcg ctatcttgta cgctttgaat acttaggttt ttggcattga cttgtacgcc
    10201 tttgccgcgt acttgcgcgc ctttgatggt agtgtcgcca ccgctttgga taagggtttg
    10261 gctgcctttg tcgccaatat ggctatggcg gtgggttacg ctatcgccat tgccgtagcc
    10321 tttgccgaca ttgccgcctg cggtaacgcc taatgaccag cctccttgtc cgaatgatac
    10381 ggcagcacct gcgttccaac ctgtcgattt gttttggctg cgttcggtat tgctttgctc
    10441 ggctgattgg agtgtgatgt cgttatcggc aatcaggatt gtgcctgctt tgccggcaat
    10501 atctgagcct gcgatgttga tattggattg ttctgctgcg cctgtggcga ttaatgtggt
    10561 tttaccgcct gcttgaattt gactcgcttg ggcttggctt gcttgaactt gggtggtttg
    10621 tcggttttgc tgttcgccgt aggttatgga gatgctgact tgtttggcat tggttgtacc
    10681 attggctaag ttttgtgcac tcttacctgt ttgataggct tgccagcctg cattggcagc
    10741 tgccatggca ttgacacgac catttttgct ttgtccgact tgtttgctgc tttgtgcgac
    10801 ggcaatcgct tgttgtgcca aatcggtaac gggcgaactg aatgccaccg ttaagccttt
    10861 ttgttcatag gtttgggtgg tattactgtt taatttgttg tgtgccgctt gaatgtctat
    10921 gctttgggca tggatgatat tgttgccttc tgggctggaa acggtactgc cgatttgttc
    10981 gtagtgtttg cctgcaacaa tggtggtatc gcctttcaag ctgcctacgg tactgcctgt
    11041 atgttcgttg ctttgggatt ggttttcttg tgtgtttgtc ttgctgccaa tagtgaagcc
    11101 gatacctgca ctcatcaatc ctgatttctg ggtttgatga taggtttcgc tttggctttg
    11161 agtttgggtt gtaccaatgc gaacatgatt gcctgcttga atccgggtgc cattatcgga
    11221 aataacattg ctgccaagga tattggcatc gtttcctgcc tgcaatacaa cttgcttgcc
    11281 ttcaaaggtg ctgctttgag cagtttcgtt atggctctgg gctttgtcgg taataatcaa
    11341 tttattgcca ccaccgcttc tgcctgtgtg tttggacgca tcatcaacat gggtcgtgtt
    11401 gatgcctgca ctgatgttga tgtcattttt ggcagacaca gcgagtgtac cgtttgcgct
    11461 gctgacttcg gcagctttgg cattgaggtt attccctgac aatagggtaa catcgccttt
    11521 tgtttgaatg ctgctgccga cttcgttcgt tgaaccgcga ataacatggt tatcggcatc
    11581 aaaatgggtt gcttgatgtt tgctggtttg taccgtatct aggttaatgt cgcgccctgc
    11641 ttgcagccgg gtttgccctt gctctgattg attgctgatt tgaccggcaa tgatgttgat
    11701 gtcttttcct gcctgcgctg ctaaaacacc tttttctttg cctgtgatat aaatacctgc
    11761 cattcggtct aggtaggtgc tgctgccttg tgtattttga ctgctggcgg cggtgctttg
    11821 gctgttgatg ttgttgcctg cgttgagcaa taatgtctgt tcgacagaaa gaatgccgcc
    11881 aatattattg atgtcttgtg tggccgtaac cgctgatttt tgcgcatgaa tacgcccacc
    11941 gatattgtct agcgtatcgg tattgataat aagcgcattg cgccctgcaa tcgtgcctga
    12001 gtttttcagg ctgcctgaaa cattgatttg tgtattgctg cctgacaaca atgcaccttt
    12061 accgtctatg tcgccattct taacgcgtac ataaacctgt ggcaccaata cggtttgtgt
    12121 gccgccatca ggaagtttaa cttctttttg taccaaccaa acaatatcgc tggtcagttg
    12181 cgctacttgc tcggcactta atgcaatgcc aacgctgaga ttcatggagc gtgccgcagt
    12241 cgcgccatta tccattaagg ctttaaattg ttcttcgtcg ttttgataac cgtctaaacg
    12301 acgatgccct gtcagctctg cgatctgttc attgattaaa cgttgctcgt aataaccatc
    12361 acccaaacgt ttatgtaaat tgtttgggtc tagtttgagg ctgtccagca tatagtcact
    12421 acccaaccat tgacggtagt tggcaaagcg tggatcggtt tcaacaagat agcctttatt
    12481 gacaggattg ataatgtata agctgctgct gggtaatggg gtaaaagaat tggacgtata
    12541 gggtagcgaa ataccgttgc tttgcggcaa ctcagtgcct tggctgggcg catgatggct
    12601 taatgctttg cgatgcgatt cataggcaaa tgaacccagt gaaatgttgc gtgtgatttc
    12661 ctccggcaaa gtgtaatttt gttcgctatg tcccgttgag tctcgtcctt tatgtttctc
    12721 acgccaatag ctgtgtaatt tgccattttc actgaatact ttcttttcgc caaaggtttg
    12781 ctcgttatgc aaaccgtctt tttctgtttg cacaagcaaa tcgccgccgg cgatgatttg
    12841 gctatcggta ttaaatactt ctttaccatc aatggttaaa tcattacctg aaatgatttt
    12901 ggctggcgca gtttgggtaa cttgggtttt ttgggtgact ttttcataat cgtatttatg
    12961 ccaattttca tgcgccgctc catcaggggt gcgtaagtgg tctgattcat cgttatagac
    13021 agaccagcct aattcatgtt gcgtgccttc ccgcaataat tcgtgtcgtc caaatgcttc
    13081 gtaatcaaca atatgctcgc gccctgtttc taccaactgc gttttcaaat gctcattggt
    13141 attgtgcagc ttttctacac ctaaacgcat tttgccggcg gcttcaatgg ttgcgctggc
    13201 attgcgtatg ctttgggctt tgcctgtggc ttggctattg gtatctaatg cgccgccaac
    13261 cgccatatcg ttaccgctgt aaatcagact gttttcacgg ttgtttaatt gtccgatgcc
    13321 taaattcagg ttttcgcgtg ccgcaatggc ggcacctgta ccgttttcat cttgattgtc
    13381 taagcgggta gccgcaatag cgatattgtc accataaatc cgacctgtac cgatattatt
    13441 cacttgcccg gcttggattt tggtttgttg tccgtcaatc aagcctctat tggttaaatt
    13501 gtgctgcgtg ccaatgtctg tcgtaccgcc ggattgaatg ttgccttgtg ctgcattatc
    13561 aaggttattt gctttaatcc gaatgcgttt tcctgcttgc aaggtatgtg aatttttcag
    13621 gctgcctcgt gtactgagcg acaattcatt gcccgccacg atattgcgtt ctacataaaa
    13681 atcatcttgt aacgcaatat ccagtttatt atcagcggca agtgtgccgt tgttggataa
    13741 cgattttgcc tgaatagcaa catcacggtc tgattgtatc gtgccattcg tattatcaat
    13801 gacagcggta gattgctgac catcgtgaat aatcagttgt tgattggtcg ctatttcgcc
    13861 attttgattg ttcaggctgc ctgaaacggc taaatccgct atttctgctg ataataactt
    13921 gccatgagcg ttatccagtt gatcggtttc aatctctaac tgttggcgtg ttgtgatgtt
    13981 gccgttttga ttattcaggc tgccggcttg aatgtggacc gcatcactga taattgttcc
    14041 attgtgattg tcaaacgccg aaccttttgc atttaactga tgaatgtcta tttgtcctgc
    14101 attatttaaa ccttgttgcg cactaacatc tgtttgacca ttggcaataa tactgcctga
    14161 attatccagt gcaccatgag tacgaattat cccatcagca aaggtaggcg cagttatgtt
    14221 tgatatagaa acggttgcag tccccgtacc tgttgccgtt gttggtgtgg tagtggatga
    14281 atgggaagat gcattgtaac tattgccggt ttgattgctt gaaccatttg acgcggttgg
    14341 tgcggtatct tgtaaaccca tgcggccacg gttatccatt ttgccttgtg catcaatatg
    14401 gagtttttgt gaacctgttt gagagagttt gccttgatta ttaagtgtgt cggtatcaat
    14461 agccaaacga gcggcttcaa tggtgcctga tgtttcattt ttcaggctgc ccgaattgtg
    14521 aatcaatatt tcgcctgagg acaataatgt gccagtgttt tgaatcgact gactgtgaat
    14581 ttgagtgcct tgttgcgata ccgccgtacc gctgttttca aaggcttgac tgcggatatt
    14641 gactttgtgt tccgctgtat tattcatatc ttgcacattg gcggcagcca tcgtgccact
    14701 attgaccaaa cggccatttg catcaatcgc cacattgccg gctgaggcaa accattgccc
    14761 ctgattgcgc acggatgcat cacgatcagt gctgatcagg gtgatcttac cggcatacat
    14821 accgcccaat gcccctgtat cgatggcata cagtgagttg tcggaattta tattcgtagc
    14881 aggggagtgt gaagactgga tagagccatc agctgagaca tcatttttcc ctgccgacac
    14941 acgcacatct ttaccccaca caggcccatc aatcttaacc gcatggctca atatctgcgt
    15001 gaaatcggta tcacgtgcat ccaaaccttg tcccgtgatc gcaatatgac ccgaacgaac
    15061 ctgaaagcct gttaatgcgc ctgtttgata ttgcggttgg cctgtcgtca aagtggcacg
    15121 ggaagcattg ataaaaccac caccattgac tgcaatccct gccggattgg caataacgac
    15181 ttctgcacgt cgtccgccca cttcaatata gccattcatt tgtgaagaat ggctgctgtt
    15241 gatttggttt acaaccacac gtgcttcgcc ccttgccaac caaagattgc cttgaatcca
    15301 accgcctagc tgtgtttggg tgttgctgcg gctgttgttt aaaatcgccc cgcgattacc
    15361 cacatcaaac tgtgtatatt gattaacaga aacccctgcc gaagtagggg tttgaatatt
    15421 gacttgcggt atgccgttac ctgtttgcag aatcgtggct tgttgggttt taggagcagc
    15481 tttatcagca ataatgccat cagcaaaagc aatattggcc gtacctacag ccaaacataa
    15541 agaaaagccc aataaagaaa aagaaaagat atttgaacga caaacaggtg catgagtagt
    15601 accaaaagga acagatttca catgagcgct gcctgaatca ctatcggcac agcttttacc
    15661 ttcgcgcttg gtagtttcag caacggctac cacagcccca cgtttgcggt tgaaaattac
    15721 acgatagaga gttttattca tgatttcagt tatttgattt ttatagagtt attagaaaaa
    15781 attggatagt ctgaccattc tagatcaagg attttggcga gtcaattacc gccattttac
    15841 tgccatttgt ttattaaatt agggacttta ctagataacg gttaaaaatc ccattcgaac
    15901 gaaatggcaa ggtttatacc gtcgttgtcc ctaatgcgca atcagcaaca ttattgccga
    15961 ttatccgaga gaaagttaag tctgatggca ttgtgtatac ggataccttt cgtagttatg
    16021 atgtacttga tgtcagtgaa tttagccatt tacgcaagtt ttccagtatt tgactggcaa
    16081 tttaaaacaa tcggaagttg tcccatttcc agtatttgac tggcaattta aaacagtcgg
    16141 attttgtccc atttgttggc caagtcttta cttgcttggc cgtttgaatt taaaaagcag
    16201 tctttctact ttccgacctt ttttctgttg taaggtctat gatccaatag cattcccaaa
    16261 gagcattttg gacggtattt aaaggaatgt gaatagcgtt ttaacaacag tgaaatagaa
    16321 tctaaaattc agattt
//
LOCUS       DAXIDM010000042        16114 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000042 DAXIDM010000000
VERSION     DAXIDM010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 16114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16114
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.042"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(355..777)
                     /locus_tag="ACFOAE_001105"
     CDS             complement(355..777)
                     /locus_tag="ACFOAE_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HFC6884605.1"
                     /translation="MQVTSKWIDGMCFVGTTEGGHSVVMEGSAAEGAAKRGPSPLEML
                     LLGVAGCSSIDVVMIAEKQRQKVTDCRATVTAKRADDAPRVFTEIHIHFKVFGHDLKE
                     SAIERAVQMSAEKYCSASIMLGKAAKITHSFEIAGADK"
     gene            complement(895..1566)
                     /locus_tag="ACFOAE_001106"
     CDS             complement(895..1566)
                     /locus_tag="ACFOAE_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3108 domain-containing protein"
                     /protein_id="HFC6884606.1"
                     /translation="MMKTFKNIFSAAILSAALPCAYAAGLPQSAVLHYSGSYGIPATM
                     TFERSGNAYKIVSTIKVPLYNIRFESGGTVVGNTLHPTYYRDIRRGKLYAEAKFADGS
                     VTYGKAGESKTEQSPKAMDLFTLAWQLAANDAKLPSGLKITNGKKLYSVGGLNKAGTG
                     KYSIGGVETEVVKYRVRRGDDTVMYFFAPSLNNIPAQIGYTDDGKTYTLKLKSVQING
                     QSAKP"
     gene            complement(1582..2208)
                     /gene="purN"
                     /locus_tag="ACFOAE_001107"
     CDS             complement(1582..2208)
                     /gene="purN"
                     /locus_tag="ACFOAE_001107"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFC6884607.1"
                     /translation="MKNIVILISGRGSNMQAIVNAAIPNVRIAAVLSNSETAAGLQWA
                     AGQGIPTDSLNHKNFESRLAFDTAMMEKIDAYQPDLVVLAGFMRILTPEFCAHYEGRL
                     MNIHPSVLPSFTGLHTHERALEAGCRVAGCTIHFVTAELDCGPIVSQGIVPILDGDTA
                     DDVAARVLAVEHKLYPKAVADFAAGRLIIEGNRVRNSENADAARFLTA"
     gene            complement(2315..3121)
                     /locus_tag="ACFOAE_001108"
     CDS             complement(2315..3121)
                     /locus_tag="ACFOAE_001108"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFC6884608.1"
                     /translation="MNTIFKISALTLSAALALSACGKKEAASEPAAASAAQGDTSSIG
                     STMQQASYAMGVDIGRSLKQMKEQGAEIDLKVFTEAMQAVYDGKEIKMTEEQAQEVMM
                     KFLQEQQAKAVEKHKAEAKANKEKGEAFLKENAAKDGVKTTASGLQYKITKQGEGKQP
                     TKDDIVTVEYEGRLIDGTVFDSSKANGGPVTFPLSQVIPGWTEGVQLLKEGGEATFYI
                     PSNLAYREQGAGDKIGPNATLVFDVKLVKIGAPENAPAKQPAQVDIKKVN"
     gene            complement(3380..3820)
                     /locus_tag="ACFOAE_001109"
     CDS             complement(3380..3820)
                     /locus_tag="ACFOAE_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HFC6884609.1"
                     /translation="MPKATFYTHVAQVPIFTCRLIARAIRDGGRILVWSDSFGRLQEL
                     DKMLWQYEAESFIPHEIWEMEEAMPSETSVLLACGGNPPRIPEGMTVLNLSDGFWNTA
                     PVLPARVLEIVGNSLEDLADARERFTAYRRSGFAIEHHGMEGKA"
     gene            complement(3883..5289)
                     /locus_tag="ACFOAE_001110"
     CDS             complement(3883..5289)
                     /locus_tag="ACFOAE_001110"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0019538 - protein metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HFC6884610.1"
                     /translation="MEFSTKTEILQEQQAGAQLFVCTEEAQLNHPTALALLSSLEEGQ
                     NFADTKIPTGNGLQAVAVCCLKSTGRAALNKAAAEAAKWAQNQETVNVDIHAFDEAQA
                     AAVAEAFAIAFGNAAYRFDRYKKEAKPAKFETAVFHSAHEAVVKEALRVAEAQVYGQS
                     LCRDLGNAAPNECTPEFLARTAKAEAEKLGAHAKIIEKDYIKENMGSFWSVAKGSAEA
                     PYLVELSYFGAADKEAAPVVLVGKGITFDTGGISLKPGLNMDEMKFDMCGAATVISTF
                     CAAVKLQLPINLIAVVATCENMPSGAANKPGDVVKSMKGLTIEVLNTDAEGRLILCDA
                     LTYAEQFKPKAVIDVATLTGACIVALGHDVSGVMGNNQDLIDSLLAASYNVDDKAWQL
                     PLFETYKDQLKSNFADIPNIGTPGAGTITAATFLSYFTEGYPWAHLDIAGTAWKSGAE
                     KGATGRPVPLLLNYLRNL"
     gene            5459..6574
                     /gene="lptF"
                     /locus_tag="ACFOAE_001111"
     CDS             5459..6574
                     /gene="lptF"
                     /locus_tag="ACFOAE_001111"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HFC6884611.1"
                     /translation="MIYQRNLIKELSFTAVGIFVVLLAVLVSTQAINLLGRAADGRVA
                     IDAVLALVGFWVIGMTPLLLVLTAFISTLTVLTRYWRDSEMSVWLSCGLALKQWIRPV
                     MQFAVPFAVLVAVMQLWVIPWAELRSREYAEILKQKQELSLVEAGGFNSLGKRNGRVY
                     FVETFDTESGIMKNLFLREQDKNGGDNIIFAKEGNFSLNDNKRTLELRHGYRYSGTPG
                     RADYNQVSFQKLNLIISTTPKLIDPVSHRRTIPTAQLIGSSNPQHQAELMWRISLTVS
                     VLLLCLLAVPLSYFNPRSGHTYNILIAIGLFLIYQNGLTLLFEAVEDGKIHFWLGLLP
                     MHIIMFVIAIVLLRVRSMPSQPFWQAVGKSLTLKGGK"
     gene            6571..7641
                     /gene="lptG"
                     /locus_tag="ACFOAE_001112"
     CDS             6571..7641
                     /gene="lptG"
                     /locus_tag="ACFOAE_001112"
                     /EC_number="7.5.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015221 - lipopolysaccharide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HFC6884612.1"
                     /translation="MNLISRYIIRQMAVMAVYALLAFLALYSFFEILYETGNLGKGSY
                     GIWEMLGYTALKMPARAYELMPLAVLIGGLVSLSQLAAGSELTVIKASGMSTKKLLLI
                     LSQFGFIFAITTVALGEWVAPTLSQKAENIKAAAINGKISTGNTGLWLKEKNSIINVR
                     EMLPDHTLLGIKIWARNDKNELAEAVEADSAVLNSDGSWQLKNIRRSTLGEDKVEVSI
                     AAEENWPISVKRNLMDVLLVKPDQMSVGELTTYIRHLQNNSQNTRIYAIAWWRKLVYP
                     AAAWVMALVAFAFTPQTTRHGNMGLKLFGGICLGLLFHLAGRLFGFTSQLYGIPPFLA
                     GALPTIAFALLAVWLIRKQEKR"
     gene            7951..10536
                     /gene="acnB"
                     /locus_tag="ACFOAE_001113"
     CDS             7951..10536
                     /gene="acnB"
                     /locus_tag="ACFOAE_001113"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HFC6884613.1"
                     /translation="MLEAYRKAAAERAALGIPALPLNAQQTADLVELLKSPPAGEGEF
                     LVELLAHRVPPGVDDAAKVKASFLAAVAEGSASSPLISPEYATELLGTMLGGYNIHAL
                     IELLDDDKLAPIAAKGLKHTLLMFDSFHDVQEKAEKGNKYAQEVLQSWADAEWFASRA
                     KVPEKITVTVFKVDGETNTDDLSPAPDAWSRPDIPLHALAMLKNPRDGITPDKPGEVG
                     PIKLLEELKAKGHPVAYVGDVVGTGSSRKSATNSVIWHTGEDIPFVPNKRFGGVCLGG
                     KIAPIFFNTQEDSGALPIEVDVSALKMGDVVDILPYEGKIVKNGETVAEFELKSQVLL
                     DEVQAGGRINLIIGRGLTAKAREALKLPASTAFRLPQAPAESKAGFTLAQKMVGRACG
                     LPEGQGVRPGTYCEPRMTTVGSQDTTGPMTRDELKDLACLGFSADMVMQSFCHTAAYP
                     KPVDVKTHKELPAFISTRGGVSLRPGDGVIHSWLNRLLLPDTVGTGGDSHTRFPIGIS
                     FPAGSGLVAFAAATGVMPLDMPESVLVRFSGKLQPGVTLRDLVNAIPLYAIKQGLLTV
                     AKAGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTVKLNKEPIIEYMKSN
                     VVLMKNMIANGYQDPRTLERRIKAMEKWLANPELLEADKDAEYAAVIEINMDDIKEPI
                     IACPNDPDDVCFMSERSGTKIDEVFIGSCMTNIGHFRAASKLLEGKADTPVRLWIAPP
                     TKMDAKQLSDEGHYGVLGRAGARMEMPGCSLCMGNQAQVREGATVMSTSTRNFPNRLG
                     KNTFVYLGSAELAAICSKLGKIPTVEEYQANIGIINEQGDKIYRYMNFNEIDSYNEVA
                     ETVNV"
     gene            10678..11673
                     /locus_tag="ACFOAE_001114"
     CDS             10678..11673
                     /locus_tag="ACFOAE_001114"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006591 - ornithine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFC6884614.1"
                     /translation="MNLKNRHFLKLLDFTPEEITAYLDLAAELKAAKKAGREIQRMKG
                     KNIALIFEKTSTRTRCAFEVAARDQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDA
                     IEYRGFGQEVVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYV
                     GDARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAH
                     EAVKNVDFIHTDVWVSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAF
                     HNRETKVGEWIYETFGLNGVEVTEEVFESPASIVFDQAENRMHTIKAVMVAALGD"
     gene            complement(11896..12909)
                     /gene="ilvC"
                     /locus_tag="ACFOAE_001115"
     CDS             complement(11896..12909)
                     /gene="ilvC"
                     /locus_tag="ACFOAE_001115"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011239815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HFC6884615.1"
                     /translation="MQVYYDKDADLSLIKGKTVAIIGYGSQGHAHAANLKDSGVNVVI
                     GLRQGSSWKKAEAAGHVVKTVAEATKEADVVMLLLPDETMPAVYHAEVTANLKEGATL
                     AFAHGFNVHYNQIVPRTDLDVIMVAPKGPGHTVRSEYKRGGGVPSLIAVYQDNSGKAK
                     DIALSYAAANGGTKGGVIETTFREETETDLFGEQAVLCGGVVELIKAGFETLTEAGYA
                     PEMAYFECLHEMKLIVDLIFEGGIANMNYSISNNAEYGEYVTGPEVVNASSKEAMRNA
                     LKRIQTGEYAKMFIQEGNVNYASMTARRRLNADHQVEKVGAQLRAMMPWITANKLVDQ
                     DKN"
     gene            complement(12989..13282)
                     /locus_tag="ACFOAE_001116"
     CDS             complement(12989..13282)
                     /locus_tag="ACFOAE_001116"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative quinol monooxygenase"
                     /protein_id="HFC6884616.1"
                     /translation="MSNIKIVALVTVKPEYTETLAAQFKELVKASRAEEGNISYDLHQ
                     EIGKPNRFVFVENWKSQAAIDEHNASAHFQAFVQSVDGKTEALEIVLMNEVAD"
     gene            complement(13349..13840)
                     /gene="ilvN"
                     /locus_tag="ACFOAE_001117"
     CDS             complement(13349..13840)
                     /gene="ilvN"
                     /locus_tag="ACFOAE_001117"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HFC6884617.1"
                     /translation="MRHILSVLIENESGAMSRVVGLFSARDYNIDSLAVAPTEDKTLS
                     RMTIVTHGDEQVIEQITKQLNKLIEVIKVVDLNESRFVERELMLVKVRAAGKDRDEFL
                     RLTEIYRGSIIDVTDRSYTIEITGSTDKLDSFLETVGRAQILETVRTGAAGIGRGERI
                     LKI"
     gene            complement(13851..15578)
                     /gene="ilvB"
                     /locus_tag="ACFOAE_001118"
     CDS             complement(13851..15578)
                     /gene="ilvB"
                     /locus_tag="ACFOAE_001118"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HFC6884618.1"
                     /translation="MQLSGAQIIVQSLKAEGVEYVFGYPGGAVIEIYDALFQLNKFKH
                     ILTRHEQAAVHAADAYARVSGKVGVALVTSGPGVTNALTGIATAYTDSIPMVVISGQV
                     GNSLIGTDAFQEVDTVGITRPCVKHNFLVTDINELAETIKKAFQIAASGRPGPVVVDV
                     PKDVTQAMAKFSYPQEDIFIRSYQPVVQGHIGQIKKAVQMLASAKRPVVYFGGGVVLG
                     NASEELTRFVRMTGAPCTGTLMGLGAYPSGDRQFLGMLGMHGTYEANLAMQNADVVLA
                     VGARFDDRVVSVPSKFFEKAKKVIHIDVDPSSIAKRVKADIPIVGDVKNVLSEMVALW
                     QKQESVPSEDALGKWWKTIEEWRSRDCLWFDNGSEIIKPQYVIQKLAEITGNSAIITS
                     DVGQHQMFAAQYYPFERPRQWLNSGGLGTMGVGLPYAIGAKLAAPDQDVFCITGDGSI
                     QMNIQELSTCFQYRIPVNVITLNNGYLGMVRQWQEIYYGGRESETYFDSLPDFVKLAE
                     AYGHIGIRVDKKSDVEGALLEALNQKDRLVFIDFLTDQKQNVMPMVGNGKGLDEMVLP
                     PHMRADEKA"
BASE COUNT         3777 a         4370 c         4090 g         3877 t
ORIGIN      
        1 aaggcgaggc aacgccgtac tggtttttgt taatccacta taattcaata aattaatata
       61 tggcttaaaa taacaggatg cccgccttcc gcccgcccgc agaagcaggc gggtatcatt
      121 ttaaaacgcg gcatttaaaa tttgaccgaa aattgttgac aatccggaat caagtctgca
      181 caataccccg acaagtccaa gtattataaa ggctgaataa agaggaaaca gcaggcagat
      241 atattcggga ggtgcagtcc gaatatatct gcttttttat gcgcctccgg cttgcctgcc
      301 gcacctttcc ccttcagacg gcatcagccg tttctccata atgccgcccg atgcctattt
      361 atctgccccg gcaatttcaa aactgtgggt aatctttgcc gctttgccca acataatcga
      421 agccgaacag tatttttcgg cagacatctg aacggcgcgc tcaatggccg attctttcaa
      481 atcatgcccg aatactttga aatggatgtg gatttcggta aacacgcgcg gcgcatcgtc
      541 cgcccgtttc gccgtaaccg tcgcacggca gtcagtcact ttctgacgct gtttttcggc
      601 aatcatcacc acatcgatgc tcgaacagcc cgccacgccc aacagcagca tttccaaagg
      661 gctgggcccg cgcttggccg caccttctgc cgccgaaccc tccataacga cgctgtgccc
      721 gccttccgtc gtgccgacaa agcacattcc gtctatccat tttgatgtaa cctgcatggt
      781 gtcattcctg aaaatagcgt taaaaccgct ttgcatatgg cgttattgta aacaatttca
      841 agcggcttat gcagaaatat ggacaaaacg gcaaaaaaac acttgaaaac cgatttacgg
      901 tttggcggac tggccgttga tctgcaccga tttgagtttc agcgtatagg ttttgccgtc
      961 gtcggtatag ccgatttgtg ccggaatatt gttcagggac ggtgcgaaga aatacattac
     1021 cgtatcgtcg ccgcgccgca cccgatattt gacgacttcg gtttccacgc cgcctatgct
     1081 gtattttcct gtacccgcct tattcaaacc gccgacggaa taaagttttt tgccgttggt
     1141 gattttcagc cccgagggga gtttcgcgtc atttgccgcc aactgccagg caagcgtgaa
     1201 caaatccata gccttggggc tttgctcggt tttgctctcg cccgctttgc cgtaggttac
     1261 gctgccgtcg gcgaatttgg cttccgcata cagtttgccc ctgcgtatgt ctctatagta
     1321 ggtagggtgc agggtattgc cgacaaccgt accgccggac tcgaaacgga tattgtatag
     1381 cggcacttta atcgtcgaaa cgattttgta agcattgccg ctgcgttcaa atgtcatcgt
     1441 ggcgggaatg ccgtagctgc cggaatagtg cagcacggcg gattggggca gccctgccgc
     1501 atacgcgcac ggcagggcgg cggacaaaat ggcggcggaa aatatatttt taaaagtctt
     1561 catcatttgc tcccgcccgg tttacgccgt caggaaacgg gcggcatcgg cgttttccga
     1621 atttctgacg cggtttccct cgataatcag gcggccggcg gcaaaatcgg caacggcttt
     1681 cggataaagt ttatgctcaa cagccaaaac ccgggcggca acatcgtctg ccgtatcgcc
     1741 gtcgagtatc ggcacaatcc cttgcgatac aatcgggccg caatccagtt cggcagtaac
     1801 gaaatggatg gtgcagccgg caacgcggca gcccgcctcc aaagcgcgtt cgtgcgtatg
     1861 aagtccggta aacgagggca ggacggacgg gtgaatgttc atcagcctgc cttcgtaatg
     1921 ggcacagaac tcaggggtca gaatccgcat aaaacctgcc aaaaccacca agtcgggttg
     1981 atatgcgtcg attttttcca tcatggcggt atcgaaggca agtcgtgatt caaagttttt
     2041 atgattcagg ctgtcggtcg gaataccctg accggccgcc cattgcaaac cggcagccgt
     2101 ttcgctgttg ctcaacacgg cggcaatacg gacgttggga atggcggcat tgacgattgc
     2161 ctgcatattg ctgccgcgtc cggaaatcag gatgacgatg tttttcataa tggtgcgctt
     2221 ttgaaaggga tgccatctga accgctgttt ggtggtttca gacggcattt gccgtaaaaa
     2281 tgcccgaaaa cctgtttcgg gcatggattc ggacttaatt tacttttttg atgtcgactt
     2341 gagccggctg cttggcgggc gcgttttcgg gtgcgccgat tttgaccagt ttcacatcaa
     2401 ataccaaagt ggcgttcggg ccgattttgt cgcccgcacc ctgttcgcgg taggcaaggt
     2461 tggacgggat gtagaacgtg gcttcgccgc cttctttcag aagctgtacg ccttcggtcc
     2521 aacccggaat cacttggctc aaagggaagg tgaccgggcc gccgttggct ttgctgctgt
     2581 cgaataccgt accgtcaatc aggcggcctt cgtattccac ggtaacgatg tcgtctttgg
     2641 tcggctgttt gccttcgccc tgtttggtga ttttgtattg caggccggaa gcagtggtct
     2701 tcacgccgtc tttggcggca ttttctttca gaaaggcttc gcctttttct ttattggcct
     2761 tcgcttccgc cttgtgtttt tctacggctt tagcctgttg ttcctgaagg aatttcatca
     2821 tgacttcctg agcctgctct tcagtcattt tgatttcttt gccgtcatac actgcctgca
     2881 tggcttcggt aaagactttc aaatcgattt ccgcaccctg ttccttcatt tgcttcaggg
     2941 agcgtccgat gtccacgccc atcgcatagc ttgcctgctg catcgtgctg ccgatcgaag
     3001 aggtgtcgcc ctgcgcggca gaagcggcgg caggttcgga tgctgcttct tttttgccac
     3061 aggcggaaag tgccaaagcg gcggaaaggg tcagtgcgct gattttgaaa atggtgttca
     3121 tgatggatct tcgctgtcga taaggtcgga aaaacgggat tatagccgag tttgaatgtt
     3181 tcaacacaca ggatgacaca taaagcgtca atcgtgtgtt gccctgtttt ggaagggatt
     3241 gaaccttcca aaataagttt tgattctacc gccccgaggg acagatgtcc aagtggcggg
     3301 gttcaaccga taaggaaatt ttaatcaaat agaatcaagc ctgtttaaat tttgtaaatg
     3361 cggcatttca gacggcattt tatgccttgc cctccatgcc gtgatgttcg atggcaaaac
     3421 cgcttcggcg gtaggcggta aagcgttcgc gcgcgtcggc gagatcttcc aagctgttgc
     3481 cgacgatttc caaaacgcgc gcgggcaaga ccggagcggt gttccaaaaa ccgtcggaca
     3541 ggttcaaaac agtcatgcct tcgggaattc ggggcggatt gccgccgcaa gcaagcagga
     3601 cggatgtttc agacggcatg gcttcttcca tttcccaaat ttcgtgcgga atgaaactct
     3661 cggcttcgta ttgccaaagc attttgtcca attcctgaag ccgcccgaac gaatcggacc
     3721 acaccagtat cctgccgccg tcccgaatcg cacgggcaat caggcggcag gtgaaaatcg
     3781 gaacttgggc aacgtgcgtg taaaaggtgg ctttcggcat attgtttgag catttggcag
     3841 gacgatgccg tctgaaaggc ttcagacggc attgtggcaa aattaaagat tccgcagata
     3901 gttcagcagc aagggaacgg gacggccagt cgcacctttt tccgctccgg atttccacgc
     3961 cgtacccgcg atgtcaaggt gcgcccacgg gtagccttcg gtgaagtaag acaggaatgt
     4021 tgcggcggta atcgtgcccg cgccgggcgt gccgatgttt ggaatgtcgg caaagttgga
     4081 tttgagttgg tctttgtagg tctcaaagag cggcagttgc catgctttgt cgtccacgtt
     4141 gtaggaagcg gcaagcaggc tgtcgatcaa atcctgattg ttgcccatca cgccgctgac
     4201 atcgtgcccc aaggcaacaa tacacgcgcc ggtcagggtg gcgacgtcga tgacggcttt
     4261 gggtttgaac tgctcggcgt aagtgagcgc gtcgcacaaa atcagacggc cttcggcatc
     4321 ggtgttcaac acttcgatgg tcagaccttt catacttttc acgacatcgc ccggtttgtt
     4381 tgccgcgccg gaaggcatat tttcacaagt ggcgacgacg gcaatcaggt taatcggcag
     4441 ttgcagtttg acggcggcgc agaaggtgct gatgacggtt gccgcgccgc acatatcaaa
     4501 cttcatttcg tccatgttca ggccgggctt gagggagatg ccgccggtgt cgaaggtaat
     4561 gcctttgccg accaatacca caggcgcggc ttctttgtcg gctgcaccga aatagctcag
     4621 ttcgaccaaa tagggggctt ccgcgctgcc tttggcgacc gaccaaaacg aacccatgtt
     4681 ttctttgatg tagtcttttt cgatgatttt ggcgtgcgcg cccagttttt cggcttcggc
     4741 tttggcggtg cgcgctaaaa attcgggcgt gcattcgttg ggcgcggcgt tgcccaagtc
     4801 gcggcagagg ctttgtccgt aaacttgcgc ttcggcgacg cgcaaggctt ctttaacgac
     4861 ggcttcgtgt gcgctgtgga acacggcggt ttcaaatttg gcgggcttgg cttctttttt
     4921 gtagcggtcg aaacggtagg cggcgttgcc gaacgcaatc gcaaacgctt cggctacggc
     4981 ggcggcttgc gcttcatcga aggcatggat gtccacattg accgtttcct gattttgcgc
     5041 ccatttggcg gcttcggcgg cggccttgtt caatgcggcg cggccggtgc ttttcagaca
     5101 gcatacggca acagcctgca aaccgttgcc tgtcgggatt tttgtgtcgg caaaattttg
     5161 accttcttca agcgaagaca aaagggcaag ggcggtcgga tggtttaatt gcgcctcttc
     5221 ggtgcagaca aataactgtg cgcctgcctg ctgttcctgc aagatttcgg tttttgtgct
     5281 aaattccacg tttattctcc tgattgagac ggttgtcggt agttttcgga cggcctttcg
     5341 ctcaaaagac cgtctgaaga cggctggcac gattgtaccc catttgaagc accgtctgaa
     5401 accttgcgcg gacaatccgc ctgcgccgaa ccgcttaccg ccccctgacc gcgattctat
     5461 gatttatcaa agaaacctca tcaaagaact ctcttttacc gccgtcggca ttttcgtcgt
     5521 cctcttggcg gtattggtct ccacgcaggc aatcaacctg ctcggccgtg ccgccgacgg
     5581 gcgtgtcgcc atcgatgccg tgttggcatt ggtcggcttc tgggtcatcg gtatgacgcc
     5641 gcttttgctg gtgttgaccg catttatcag tacgttgacc gtgttgaccc gctactggcg
     5701 cgacagcgaa atgtcggtct ggctatcctg cggattggca ttgaaacaat ggatacgccc
     5761 ggtgatgcag tttgccgtgc cgtttgccgt tttggttgcc gtcatgcagc tttgggtgat
     5821 accgtgggca gagctacgca gccgcgaata cgctgaaatc ctgaagcaga agcaggaatt
     5881 gtctttggtg gaggcaggcg ggttcaacag tttgggcaag cgcaacggca gggtttattt
     5941 tgtcgaaacc ttcgataccg aatccggcat catgaaaaac ctgttcctgc gcgaacagga
     6001 caaaaacggc ggcgacaaca tcatcttcgc caaagaaggt aacttctcgc tgaacgacaa
     6061 caaacgcacg ctcgaattgc gccacggcta ccgttacagc ggcacgcccg gacgcgccga
     6121 ctacaatcag gtttccttcc aaaaactcaa cctgattatc agcaccacgc caaaactcat
     6181 cgaccccgtt tcccaccgcc gtaccattcc gaccgcccaa ctgattggca gcagcaaccc
     6241 gcaacatcag gcggaattga tgtggcgcat ctcgctgacc gtcagcgtcc tcctactctg
     6301 cctgcttgcc gtgccgcttt cctatttcaa cccgcgcagc ggacatacct acaatatctt
     6361 gattgccatc ggtttgtttt taatttacca aaacgggctg accctgcttt ttgaagccgt
     6421 ggaagacggc aaaatccatt tttggctcgg actgctgcct atgcacatca tcatgttcgt
     6481 catcgcaatc gtacttctgc gcgtccgcag catgcccagc cagcccttct ggcaggcggt
     6541 tggcaaaagt ctgacattga aaggcggaaa atgaacctga tttcacgtta catcatccgt
     6601 caaatggcgg ttatggcggt ttacgcgctc cttgccttcc tcgctttgta cagctttttt
     6661 gaaatcctgt acgaaaccgg caacctcggc aaaggcagtt acggcatatg ggaaatgctg
     6721 ggctacaccg ccctcaaaat gcccgcccgc gcctacgaac tgatgcccct cgccgtcctt
     6781 atcggcggac tggtctctct cagccagctt gccgccggca gcgaactgac cgtcatcaaa
     6841 gccagcggca tgagcaccaa aaagctgctg ttgattctgt cgcagttcgg ttttattttt
     6901 gctattacca ccgtcgcgct cggcgaatgg gttgcgccca cactgagcca aaaagccgaa
     6961 aacatcaaag ccgcggccat caacggcaaa atcagtaccg gcaataccgg cctttggctg
     7021 aaagaaaaaa acagcattat caatgtgcgc gaaatgttgc ccgaccatac cctgctgggc
     7081 attaaaatct gggcccgcaa cgataaaaac gaactggcag aggcagtgga agccgattcc
     7141 gccgttttga acagcgacgg cagttggcag ttgaaaaaca tccgccgcag cacgcttggc
     7201 gaagacaaag tcgaggtctc tattgcggct gaagaaaact ggccgatttc cgtcaaacgc
     7261 aacctgatgg acgtattgct cgtcaaaccc gaccaaatgt ccgtcggcga actgaccacc
     7321 tacatccgcc acctccaaaa caacagccaa aacacccgaa tctacgccat cgcatggtgg
     7381 cgcaaattgg tttaccccgc cgcagcctgg gtgatggcgc tcgtcgcctt tgcctttacc
     7441 ccgcaaacca cccgccacgg caatatgggc ttaaaactct tcggcggcat ctgtctcgga
     7501 ttgctgttcc accttgccgg acggctcttc gggtttacca gccaactcta cggcatcccg
     7561 cccttcctcg ccggcgcact acctaccata gccttcgcct tgctcgccgt ttggctgata
     7621 cgcaaacagg aaaaacgcta aaccaatgcc gtctgacccc cttcggacgg cattggtttt
     7681 tattatcata ttcctgtaga cagatagccg ttccctatta tagtggatta acaaaaacca
     7741 gtacggcgtt gcctcgcctt gccgtactat tgtactgtct gcggcttcgt cgccttgtcc
     7801 tgatttttgt taatccacta tacattacct gtcataacag ttccattttt gttaaaacta
     7861 gtctatgata gcggtacaaa tattgtttac aatatttaac gcaaatcatt tgcaacccga
     7921 caaaagaaaa acagaaaaag gaacaaagag atgttagaag cctatcgtaa agccgccgcc
     7981 gagcgcgccg ccctcggcat tcccgccctc cctttgaacg cgcagcaaac cgccgatttg
     8041 gttgagctgc tgaaaagccc gcccgcaggc gaaggcgagt tcttggtcga actgcttgcc
     8101 caccgtgttc cgcccggtgt ggacgatgcc gccaaagtca aagcctcatt cctggctgcc
     8161 gttgccgaag gcagcgcgtc cagcccgctg atctcccccg aatatgcgac cgaactctta
     8221 ggtacgatgc tcggcggtta caatatccac gccttaatcg aactcttgga cgacgacaaa
     8281 ctcgcgccca ttgccgccaa aggcttgaaa catacgcttc tgatgttcga ttccttccac
     8341 gacgttcagg aaaaagccga aaaaggcaac aaatacgcgc aagaagtttt gcaatcttgg
     8401 gcagatgccg aatggttcgc ctcacgcgcc aaagttcccg aaaaaatcac cgttaccgtt
     8461 ttcaaagttg acggcgaaac caatacagac gacctctccc ccgcgcccga cgcgtggagt
     8521 cgtcccgata ttccgctgca cgcgctggca atgctgaaaa acccgcgcga cggcatcacg
     8581 cccgacaaac cgggcgaagt cggtccgatt aaattgttgg aagaactcaa agccaaaggc
     8641 catccggttg cttacgtcgg cgacgtggtc ggtactggtt cttcacgcaa atccgcgacc
     8701 aactccgtca tttggcatac cggcgaagac attccgttcg tgccgaacaa acgcttcggc
     8761 ggcgtatgtt tgggcggcaa aatcgcgccg attttcttca atacccaaga agattccggc
     8821 gcgctgccga ttgaagtcga tgtatctgct ctaaaaatgg gcgatgtcgt cgatatcctg
     8881 ccttatgaag gcaaaatcgt gaaaaacggc gagactgttg ccgagtttga attgaaatca
     8941 caagtattgc tggacgaagt gcaagccggc ggccgtatca acctgattat cggccgaggt
     9001 ctgaccgcca aagcgcgcga agccctgaaa ctgcctgcct ctactgcatt ccgcctgccg
     9061 caagcgcctg ccgaaagcaa agccggtttc accttggcgc aaaaaatggt cggccgcgcc
     9121 tgcggtctgc ccgaaggaca aggcgtgcgc ccgggtactt actgcgaacc gcgtatgacg
     9181 acggtcggct cgcaagacac gaccggcccg atgacccgcg acgagttgaa agacttggct
     9241 tgtttgggct tctccgccga tatggtgatg cagtctttct gccacaccgc cgcctatccg
     9301 aaacctgtcg atgtaaaaac ccataaagaa ctgcccgcct ttatttccac ccgtggcggc
     9361 gtgtcactgc gtccgggcga cggcgtcatc cactcgtggc tcaaccgcct gctgctgccc
     9421 gataccgtcg gcaccggcgg cgacagccat acccgtttcc ccatcggtat ttccttcccc
     9481 gccggctccg gcttggttgc ctttgccgcc gcaacgggcg taatgccgct cgatatgccc
     9541 gagtctgtat tagtacgctt cagcggcaag ctgcaaccgg gcgtaaccct gcgcgatttg
     9601 gtgaacgcca tcccgctgta cgcaattaaa caaggtttgc tgaccgttgc caaagccggt
     9661 aagaaaaaca tcttctctgg ccgcatcctc gaaatcgaag gcctgcccga tttgaaagtg
     9721 gaacaagcct ttgaattgac cgacgcatcc gccgaacgct ccgccgccgg ctgtaccgtg
     9781 aagctcaata aagagccgat tatcgagtac atgaaatcca acgtcgtgtt gatgaaaaac
     9841 atgattgcca acggctatca agacccgcgc actttggaac gccgcatcaa agccatggaa
     9901 aaatggctgg caaatcccga gttgctcgaa gcggataaag atgccgaata cgccgccgtg
     9961 attgaaatca acatggacga catcaaagag ccgattatcg cctgcccgaa cgacccggac
    10021 gacgtgtgct tcatgtccga acgctccggc accaaaatcg acgaagtatt catcggttcg
    10081 tgtatgacca acatcggcca cttccgcgcc gcctccaaac ttttggaagg caaggcagac
    10141 acccccgtcc gcctgtggat tgcgccgccg accaaaatgg acgcgaaaca attgtccgac
    10201 gaaggacact acggcgtact cggacgtgcc ggcgcgcgta tggaaatgcc gggttgctcc
    10261 ttatgtatgg gtaatcaggc gcaagtacgc gaaggtgcga ccgttatgtc cacctccacc
    10321 cgcaacttcc cgaaccgttt gggtaaaaac acctttgttt acctcggttc ggcggaattg
    10381 gcagcgattt gctccaaact gggtaaaatc ccgaccgttg aagaatatca agccaatatc
    10441 ggcatcatca acgaacaggg cgataaaatc taccgctata tgaacttcaa cgaaatcgac
    10501 agctacaacg aagtagccga gaccgtgaac gtttaatccc cgtcatccgt atgaagtaag
    10561 ggattgaccg caatgccgtc tgaacaacct tcagacggca ttgcaacatt ccgctaaccc
    10621 ttctttccgc aaacgctgca aatacggcgt tcacgccccc acataaagga aacgacagtg
    10681 aacctgaaaa accgccattt tctgaaactt ttagacttca cgccggaaga aatcaccgcc
    10741 tacctcgacc ttgccgccga attgaaagcc gccaaaaaag cagggcgcga gattcagcgg
    10801 atgaaaggga aaaacatcgc cctgattttt gaaaaaacct ctactcggac gcgctgcgcg
    10861 tttgaagtcg ccgcgcgcga tcaaggcgcg ggagtgactt atttagagcc gtccgccagc
    10921 caaatcgggc ataaggaaag catcaaagac accgcccgcg tgttgggcag gatgtacgat
    10981 gccatcgaat atcgcggttt cggtcaggaa gttgttgaag aattggcgaa atacgcgggc
    11041 gtacccgtgt tcaacgggct gaccaacgag ttccatccca cacaaatgct tgccgacgca
    11101 ctgactatgc gcgaacacag cggcaaacct ttgaaccaaa ccgcgtttgc ctacgtcggc
    11161 gacgcgcgtt acaacatggg caattccctg ctgattttag gggcaaaatt ggggatggac
    11221 gtgcgtatcg gcgcaccgca aagcctgtgg ccgtctgaag gcattattgc cgccgcacac
    11281 gccgccgcca aagaaaccgg cgcaaaaatt accctgaccg aaaacgcgca tgaagccgtg
    11341 aagaatgttg attttattca taccgatgtg tgggtcagca tgggcgagcc gaaagaagtc
    11401 tggcaggaac gcatcgattt gctgaaagat taccgcgtta cgcccgaact gatggcggca
    11461 tcgggcaatc cgcaagtcaa attcatgcac tgcctgcccg ccttccacaa ccgcgaaacc
    11521 aaagtcggcg aatggattta cgaaaccttc gggctgaacg gtgtggaagt tacagaagaa
    11581 gtattcgaaa gccccgccag catcgtgttc gatcaggcgg aaaaccgtat gcacacgatt
    11641 aaagcggtaa tggtcgcggc tttgggcgac tgacagaact gtgcctgttt aaattcatcc
    11701 gcaacacaga taccgtctga acacgatgtt cagacggtat ccatatatag tggattaaat
    11761 ttaaaccagt acggcgttgc ctcgccttgc cgtactattt gtactgtctg cggcttcgtc
    11821 gccttgtcct gatttttgtt aatccactat aaaaaactgc ctacacgatg tgtaggcagt
    11881 cccgtttgaa aacaatcagt ttttgtcttg gtcaaccaat ttgttggcag taatccaagg
    11941 catcatggca cgcagttgtg cgccgacttt ttcaacttgg tggtcggcat tcagacggcg
    12001 gcgggcagtc atagacgcat agttgacatt accctcttgg ataaacattt ttgcgtattc
    12061 gccggtttgg atgcgtttca gggcattgcg catggcttct ttgctggaag cattgaccac
    12121 ttcagggccg gtaacgtatt cgccgtactc cgcattgttg gaaatggagt agttcatatt
    12181 ggcaataccg ccttcgaaaa tcaggtcaac gatcagtttc atttcgtgca gacattcgaa
    12241 gtaagccatt tcaggcgcgt aaccggcttc ggtcagggtt tcaaaacctg ctttgatcaa
    12301 ctcgaccacg ccgccgcaca atacggcttg ttcgccgaac agatcggttt cggtttcttc
    12361 gcggaaagtg gtttcaatca caccgccttt ggtgccgccg ttggcagccg cataagacag
    12421 ggcgatgtct ttggccttgc cggaattgtc ttggtaaacg gcaatcagag aaggcacgcc
    12481 gccgccgcgt ttgtattcac tgcgtacggt atgacccgga cctttggggg caaccataat
    12541 cacgtccaag tcggtacgcg gaacgatttg gttgtagtgc acgttgaagc cgtgtgcaaa
    12601 tgccagcgtt gcgccttctt tcaaattggc tgtaacttcg gcgtgataga cggcaggcat
    12661 ggtttcgtca ggcagcagca gcataacgac atcggcttct ttggtcgctt cagcaacggt
    12721 tttgacgaca tgaccggctg cttcggcttt tttccaagaa gaaccttggc gcagaccaat
    12781 caccacgttt acacccgaat ctttcaggtt ggcggcatgg gcatgacctt gcgaaccgta
    12841 accgatgatg gcaacggttt tgcctttgat tagggacaga tcggcatctt tatcgtaata
    12901 gacttgcatt tgatttcctt taaggtaaat ggttgtcgaa gccttaaaat gttgagcggc
    12961 ttcggacggg ttaaacagag tgtgccgctt aatcggcaac ttcattcatc aatacgattt
    13021 ccaacgcttc ggttttgccg tcgacggact ggacgaaggc ttggaaatgc gcgctggcgt
    13081 tatgttcgtc aatagctgct tgagatttcc aattttccac gaaaacaaaa cggttcggtt
    13141 tgccgatttc ctgatggaga tcgtagctga tgttgccctc ttctgcacgg ctggctttga
    13201 ccagttcttt aaactgtgct gccagtgttt ctgtgtattc cggtttgacg gtaaccagtg
    13261 cgacaatttt aatgttcgac ataaatctct cctgccgttc gtttttcaga cgacattcaa
    13321 ataccgtgcc gtctgaaagg ttacggcgtt aaattttcaa aatacgctca ccgcgaccga
    13381 tgccggccgc gcctgtgcgt acggtttcca aaatttgggc gcgtccgacc gtttccaaaa
    13441 aggaatccag cttgtctgtc gagccggtaa tttcaatcgt atagctgcgg tcggttacgt
    13501 cgatgatgct gccccggtag atttcggtca agcgtaaaaa ttcgtcgcgg tctttgccgg
    13561 cggcacggac ttttaccaac atcagttcgc gttcgacaaa acggctttcg ttcaaatcga
    13621 ccactttaat cacttcaatc aatttattga gttgcttggt gatttgttcg atgacctgct
    13681 cgtcgccgtg ggtaacgatg gtcatacggg acagggtttt gtcttcggtc ggcgcaaccg
    13741 ccaaagaatc gatattgtaa tcgcgtgcag agaacaaacc gaccacgcgg ctcatcgcac
    13801 ctgattcgtt ttcaatcaga acagataaga tatgtcgcat ttgcctctcc ttacgccttt
    13861 tcgtccgcac gcatatgcgg cggaagtacc atttcgtcca aacctttgcc gttaccgacc
    13921 atgggcatca cattctgttt ctggtcggtc aggaagtcga taaacaccag cctgtctttt
    13981 tggttcaatg cttccaacaa cgcaccttcc acatcagact tcttgtccac gcggatgccg
    14041 atatgaccgt atgcctcggc aagtttgacg aaatcgggca aagaatcgaa ataagtttcc
    14101 gactctcggc cgccgtaata tatttcctgc cactggcgta ccataccgag ataaccgttg
    14161 ttcagcgtaa tgacgttaac cggaatccga tattggaaac aggtggacag ctcttggatg
    14221 ttcatctgga tcgagccgtc gccggtaata cagaatacgt cttgatccgg ggcggcaagt
    14281 tttgcaccaa tcgcataagg cagaccaacg cccatcgtac ccaaaccgcc ggagttgagc
    14341 cattggcgcg gacgttcgaa gggataatat tgagccgcaa acatttgatg ctgccctaca
    14401 tccgatgtga tgattgccga attgccggta atctcggcaa gcttctgaat cacatattgt
    14461 ggcttgataa tttcgctgcc gttgtcaaac cacaagcaat cgcgggaacg ccattcctct
    14521 atggttttcc accatttgcc caaagcatct tcagacggca cggactcttg tttttgccac
    14581 agcgcaacca tctcggacaa aacgtttttc acgtcgccga caatcggaat gtccgccttc
    14641 acgcgtttgg cgatgctgga aggatcgaca tcgatatgga taaccttctt cgccttctcg
    14701 aaaaatttgg acggtacgga aaccacacgg tcgtcaaaac gcgcacctac ggcaagaacg
    14761 acatctgcat tctgcatggc aaggtttgcc tcgtaagtac cgtgcatacc gagcataccg
    14821 aggaattggc ggtcgccgga aggataagcg cccaagccca tcagcgtacc cgtgcacgga
    14881 gcacccgtca ttcggacaaa tcgggtcagc tcttcagaag cattacccaa caccacgccg
    14941 ccgccaaaat agacgaccgg acgtttggca gatgccaaca tctgcacggc ctttttaatc
    15001 tgaccgatat gcccttgaac aaccggttga tacgaacgga taaaaatgtc ttcctgagga
    15061 tagctgaatt tcgccatcgc ctgcgtaaca tctttcggga catcaaccac cacgggcccc
    15121 ggtcggccgc ttgcggcaat ttggaacgcc tttttaatgg tttccgccaa ctcattgatg
    15181 tccgtaacca ggaaattgtg tttgacgcac ggacgggtaa tacccaccgt atcaacttct
    15241 tggaacgcat ccgtaccaat cagggaattg cctacctgcc cgctgatgac caccatcgga
    15301 atcgaatccg tataggcagt agcaataccg gtcagtgcat tggtaacgcc cgggccggat
    15361 gtaaccaatg ccacgcccac cttaccgctg acgcgcgcat acgcatctgc cgcgtgtact
    15421 gccgcctgct cgtgacgggt cagaatgtgc ttgaatttat tgagttggaa aagggcatcg
    15481 tagatttcga taaccgcacc gccgggataa ccgaaaacgt actcgacacc ttcggctttg
    15541 agactctgca ctatgatttg cgcgcctgat aactgcataa cgacctcttt tatacggttt
    15601 caaaccaata gggacaaacc gctttgccac agcacctgta atgcaattcc accaagcagc
    15661 gatttagggt acgcgcattg ggggaacacg gcaacagacg gattatccaa tcaattggaa
    15721 aggaacacag agtttgtgaa aaagagtaga aacgataacg caaaccgaca gttcaatcaa
    15781 gaaaaatctt tcatctttta atattttttg aaagcagaga aattattgat tgattttaaa
    15841 agaataaaat caggagtacc ttttttgaaa gatggaaatt gttgacagtt tgtgtaggag
    15901 gggcagatgt gaaaaaccct tcttcgatat caagaattgt aaaatttaca gggtttcatc
    15961 ccaataaaga ctcgggatat tgattgaact tgattttatt tttgatatat caaaaatatt
    16021 cccaaccata cttcctgaaa atggctcatt gcaccggact gtattggacg gcattgacag
    16081 aaccaagagg gctaacaacg acttaatata ttga
//
LOCUS       DAXIDM010000043        15528 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000043 DAXIDM010000000
VERSION     DAXIDM010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 15528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15528
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.043"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            6..81
                     /locus_tag="ACFOAE_001119"
     tRNA            6..81
                     /locus_tag="ACFOAE_001119"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Trp,seq:cca)
     gene            196..474
                     /gene="secE"
                     /locus_tag="ACFOAE_001120"
     CDS             196..474
                     /gene="secE"
                     /locus_tag="ACFOAE_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFC6884619.1"
                     /translation="MTEHTPEKKNVKVDQLVVQDKESASNSGKEGFFAYFSNSWSEFK
                     KVVWPKREDAVRMTVFVIVFVAVLSIFIYAADTAISWLFFDVLLRREG"
     gene            476..1012
                     /gene="nusG"
                     /locus_tag="ACFOAE_001121"
     CDS             476..1012
                     /gene="nusG"
                     /locus_tag="ACFOAE_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFC6884620.1"
                     /translation="MSKKWYVVQAYSGFEKNVQRILEERIAREEMGDYFGQILVPVEK
                     VVDIRNGRKTISERKSYPGYVLVEMEMTDDSWHLVKSTPRVSGFIGGRANRPTPISQR
                     EAEIILQQVQTGIEKPKPKVEFEVGQQVRVNEGPFADFNGVVEEVNYERNKLRVSVQI
                     FGRETPVELEFSQVEKIN"
     gene            1113..1547
                     /gene="rplK"
                     /locus_tag="ACFOAE_001122"
     CDS             1113..1547
                     /gene="rplK"
                     /locus_tag="ACFOAE_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFC6884621.1"
                     /translation="MAKKIIGYIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNA
                     ATQGMEPGLPIPVVITAFADKSFTFVMKTPPASILLKKAAGLQKGSSNPLTNKVGKLT
                     RAQLEEIAKTKDPDLTAADLDAAVRTIAGSARSMGLDVEGVV"
     gene            1547..2242
                     /gene="rplA"
                     /locus_tag="ACFOAE_001123"
     CDS             1547..2242
                     /gene="rplA"
                     /locus_tag="ACFOAE_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFC6884622.1"
                     /translation="MAKVSKRLKALRSSVEANKLYAIDEAIALVKKAATAKFDESVDV
                     SFNLGVDPRKSDQVIRGSVVLPKGTGKITRVAVFTQGANAEAAKEAGADIVGFEDLAA
                     EIKAGNLNFDVVIASPDAMRIVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VQYRTDKAGIVHATIGRASFAEADLKENFDALLDAIVKAKPAAAKGQYLKKVAVSSTM
                     GLGIRVDTSSVNN"
     gene            2472..2972
                     /gene="rplJ"
                     /locus_tag="ACFOAE_001124"
     CDS             2472..2972
                     /gene="rplJ"
                     /locus_tag="ACFOAE_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFC6884623.1"
                     /translation="MSLNIETKKVAVEEISAAIANAQTLVVAEYRGISVSSMTELRAN
                     ARKEGVYLRVLKNTLARRAVQGTSFAELADQMVGPLVYAASEDAVAAAKVLHQFAKKD
                     DKIVVKAGSYNGEVMNAAQVAELASIPSREELLSKLLFVMQAPVSGFARGLAALAEKK
                     AGEEAA"
     gene            3030..3401
                     /gene="rplL"
                     /locus_tag="ACFOAE_001125"
     CDS             3030..3401
                     /gene="rplL"
                     /locus_tag="ACFOAE_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFC6884624.1"
                     /translation="MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPA
                     GAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVS
                     KAEAEDIQKQLEEAGAKVEIK"
     gene            3592..7770
                     /gene="rpoB"
                     /locus_tag="ACFOAE_001126"
     CDS             3592..7770
                     /gene="rpoB"
                     /locus_tag="ACFOAE_001126"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFC6884625.1"
                     /translation="MSYSFTEKKRIRKSFAKRENVLEVPFLLATQIDSYAKFLQLENA
                     FDKRTDDGLQAAFNSIFPIVSHNGYARLEFVHYTLGEPLFDIPECQLRGITYAAPLRA
                     RIRLVILDKEASKPTVKEVRENEVYMGEIPLMTPSGSFVINGTERVIVSQLHRSPGVF
                     FEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDLLYFRIDRRRKMPVTILLKALG
                     YNNEQILDIFYDKETFYLSSNGVQTDLVADRLKGETAKVDILDKEGNVLVAKGKRITA
                     KNIRDITNAGLTRLDVEPESLLGKALAADLIDSETGEVLASANDEITEELLAKFDING
                     VKEITTLYINELDQGAYISNTLRTDETAGRQAARVAIYRMMRPGEPPTEEAVEQLFNR
                     LFFSEDSYDLSRVGRMKFNTRTYEQKLSEAQQNSWYGRLLNETFAGAADKGGYVLSVE
                     DIVASIATLVELRNGHGEVDDIDHLGNRRVRSVGELTENQFRSGLARVERAVKERLNQ
                     AESENLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEVTHKRRVSALGPGGLT
                     RERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNDYGFLETPYRRVIDG
                     KVTEEIDYLSAIEEGRYVIAQANADLDSDGNLIGDLVTCREKGETIMATPDRVQYMDV
                     ATGQVVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPMVGTGIERSVAVDSA
                     TAIVARRGGVVEYVDANRVVIRVHDDEATAGEVGVDIYNLVKFTRSNQSTNINQRPAV
                     KAGDVLQRGDLVADGASTDLGELALGQNMTIAFMPWNGYNYEDSILISEKVAADDRYT
                     SIHIEELNVVARDTKLGAEDITRDIPNLSERMQNRLDESGIVYIGAEVEAGDVLVGKV
                     TPKGETQLTPEEKLLRAIFGEKASDVKDTSLRMPTGMSGTVIDVQVFTREGIQRDKRA
                     QSIIDSELKRYRLDLNDQLRIFDNDAFDRIERMIVGQKANGGPMKLAKGSEITTEYLA
                     GLPSRHDWFDIRLTDEDLAKQLELIKVSLQQKREEADELYEIKKKKLTQGDELQPGVQ
                     KMVKVFIAIKRRLQAGDKMAGRHGNKGVVSRILPVEDMPYMADGRPVDIVLNPLGVPS
                     RMNIGQILEVHLGWAAKGIGERIDRMLKEQRKAGELREFLNRLYNGSGKKEDLDALTD
                     EEIIELASNLRKGASFASPVFDGAKESEIREMLNLAYPSDDPEVEKLGFNDSKTQITL
                     YDGRSGEAFDRKVTVGVMHYLKLHHLVDEKMHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYENIVKGEHKIDAGMPESFNVLVK
                     EIRSLGLDIDLERY"
     gene            7927..12102
                     /gene="rpoC"
                     /locus_tag="ACFOAE_001127"
     CDS             7927..12102
                     /gene="rpoC"
                     /locus_tag="ACFOAE_001127"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFC6884626.1"
                     /translation="MNLLNLFNPLQTAGMEEEFDAIKIGIASPETIRSWSYGEVKKPE
                     TINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKFKGVTCEKCGVEVTLSKVRRE
                     RMGHIELAAPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAFVVTDPGMTPLQRRQ
                     LLTEDDYYNKLDEYGDDFDAKMGAEGIRELLRTLNVAGEIEILRQELESTGSDTKIKK
                     IAKRLKVLEAFHRSGMKLEWMIMDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVIN
                     RNNRLKRLLELHAPDIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIK
                     GKGGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIFHKLEKQGL
                     ASTVKAAKKLVEQEVPEVWDILEEVIREHPIMLNRAPTLHRLGIQAFEPILIEGKAIQ
                     LHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLSPANGEPIIVPSQDI
                     VLGLYYMTRDRINAKGEGSLFADVKEVHRAYHTKQVELGTKITVRLREWVKNEAGEFE
                     PVVNRYETTVGRALLSEILPKGLPFEYVNKALKKKEISKLINASFRLCGLRDTVIFAD
                     HLMYTGFGFAAKGGISIAVDDMEIPKEKVALLAEANAEVKEIEDQYRQGLVTNGERYN
                     KVVDIWGRAGDKIAKAMMDNLSKQKVIDRDGNEVDQESFNSIYMMADSGARGSAAQIK
                     QLSGMRGLMAKPDGSIIETPITSNFREGLTVLQYFIATHGARKGLADTALKTANSGYL
                     TRRLVDVTQDLVVVEDDCGTSDGFVMKAVVQGGDVIEALRERILGRVTASDVVDPSSG
                     ETLVEAGTLLTEKLVDMIDQSGVDEVKVRTPITCKTRHGLCAHCYGRDLARGKLVNAG
                     EAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQVEAKSNGTARFSSQMRYVANN
                     KGELVVIGRSCEVVIHDDIGRERERHKVPYGAILLVQDGMAIKAGQTLATWDPHTRPM
                     ITEHAGMVKFENVEEGVTVAKQTDDVTGLSTLVVIDGKRRSSSASKLLRPTVKLLDEN
                     GVEICIPGTSTPVSMAFPVGAVITVREGQEIGKGDVLARIPQASSKTRDITGGLPRVA
                     ELFEARVPKDAGMLAEITGTVSFGKETKGKQRLIITDVDGVAYETLISKEKQILVHDG
                     QVVNRGETIVDGAVDPHDILRLQGIEALARYIVQEVQEVYRLQGVKISDKHIEVIIRQ
                     MLRRVNIADAGETGFITGEQVERGDVMAANEKALEEGKEPARYENVLLGITKASLSTD
                     SFISAASFQETTRVLTEAAIMGKQDELRGLKENVIVGRLIPAGTGLTYHRSRHQQWQE
                     VEQETAETQVTDE"
     gene            12360..12731
                     /gene="rpsL"
                     /locus_tag="ACFOAE_001128"
     CDS             12360..12731
                     /gene="rpsL"
                     /locus_tag="ACFOAE_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003093744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFC6884627.1"
                     /translation="MPTINQLVRKGRQKPVYVNKVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSL
                     DTAGVKDRKQARSKYGAKRPK"
     gene            12849..13319
                     /gene="rpsG"
                     /locus_tag="ACFOAE_001129"
     CDS             12849..13319
                     /gene="rpsG"
                     /locus_tag="ACFOAE_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008955889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFC6884628.1"
                     /translation="MPRRREVPKRDVLPDPKFGSVELTKFMNVLMIDGKKSVAERIVY
                     GALEQIEKKTGKVAIEVFNEAIANAKPIVEVKSRRVGGANYQVPVEVRPSRRLALAMR
                     WVRDAARKRGEKSMDLRLAGELIDASEGRGGALKKREEVHRMAEANKAFSHFRF"
     gene            13338..15443
                     /gene="fusA"
                     /locus_tag="ACFOAE_001130"
     CDS             13338..15443
                     /gene="fusA"
                     /locus_tag="ACFOAE_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFC6884629.1"
                     /translation="MARKTPISLYRNIGISAHIDAGKTTTTERILFYTGLTHKLGEVH
                     DGAATTDYMEQEQERGITITSAAVTSYWSGMAKQFPEHRFNIIDTPGHVDFTVEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYQVPRLAFVNKMDRQGANFFRVVEQMKT
                     RLRANPVPIVIPVGAEDNFSGVVDLLKMKSIIWNEADKGTTFTYGDIPAELVETAEEW
                     RQNMIEAAAEASEELMDKYLGGDELTEEEIVGALRQRTLAGEIQPMLCGSAFKNKGVQ
                     RMLDAVVELLPAPTDIPPVQGVNPNTEEADSRQASDEEKFSALAFKMLNDKYVGQLTF
                     IRVYSGVVKSGDTVLNSVKGTRERIGRLVQMTAADRTEIEEVRAGDIAAAIGLKDVTT
                     GETLCAESAPIILERMEFPEPVIHIAVEPKTKADQEKMGIALNRLAKEDPSFRVRTDE
                     ESGQTIISGMGELHLEIIVDRMKREFGVEANIGAPQVAYRETIRKAVKAEYKHAKQSG
                     GKGQYGHVVIEMEPMEPGGEGYEFIDEIKGGVIPREFIPSVDKGIRDTLPNGIVAGYP
                     VVDVRIRLVFGSYHDVDSSQLAFELAASQAFKEGMRQASPALLEPIMAVEVETPEEYM
                     GDVMGDLNRRRGVVLGMDDDGIGGKKVRAEVPLAEMFGYSTDLRSATQGRATYSMEFK
                     KYSEAPAHIAAAVTEARKG"
BASE COUNT         4143 a         3456 c         4014 g         3915 t
ORIGIN      
        1 tttagaggcc aatagctcaa ttggtagagt atcggtctcc aaaaccgagg gttgggggtt
       61 cgagaccctc ttggcctgcc aaataaaaaa ttaaccggcc ttgtgtcggt taattttttt
      121 gtatttgtta tttagtaaac tctcttgcca tttacatgga ttgagaatag acagatgcta
      181 tgatggataa ataatatgac agaacatacg cctgaaaaaa agaacgttaa agtggatcaa
      241 ctggttgttc aagataaaga atctgcatct aattccggta aggaagggtt ttttgcatat
      301 ttctcaaatt cttggtccga attcaaaaag gtggtttggc ctaagcgtga agatgctgtc
      361 agaatgactg tatttgttat agtgtttgtt gctgtgcttt ctatatttat ctatgcggca
      421 gatacagcaa tttcgtggtt attttttgat gtattgctga gaagggaagg ttgagatgtc
      481 gaaaaaatgg tatgttgtac aggcgtattc ggggtttgag aagaatgtcc aacgaatatt
      541 ggaagagcgc attgcccgtg aggagatggg agattatttc ggacaaattc tggtgcctgt
      601 agagaaagtt gttgatatcc gcaatggtcg taagactatt agtgaaagaa agtcatatcc
      661 tggttatgtg ctagttgaga tggaaatgac agatgactct tggcatcttg taaaaagcac
      721 cccccgtgtt tccggtttta ttggagggag ggctaataga cctacgccga ttagtcagag
      781 agaggctgaa attattttac agcaggttca gaccggcata gagaagccga aaccaaaagt
      841 tgaatttgag gtcggtcaac aggttcgtgt aaatgaaggg ccgtttgcgg attttaacgg
      901 ggtggttgag gaggtcaatt atgaacggaa taagttacgc gtgtctgttc agatatttgg
      961 tagagaaaca cccgttgagc tggagttcag ccaggttgaa aagattaact gatttttata
     1021 cttgaaaaaa aagcaataag aggatagaat caaaaattaa cttggggagc ggaaatggtt
     1081 ccgcgtctta cccgttttta ggagttcgtt aagtggcaaa gaaaattatc ggctatatta
     1141 aactgcaaat tcctgcaggt aaagccaatc catctcctcc ggttggtcct gctttgggtc
     1201 agcgcggttt gaatattatg gaattttgta aggcatttaa tgctgcaacc caaggtatgg
     1261 agcctggctt accgattccg gttgtgatta ctgcatttgc agataaatca ttcacatttg
     1321 tgatgaaaac cccgccagct tctatcttgt tgaaaaaggc tgccggtttg caaaaaggta
     1381 gttctaatcc tctgaccaac aaagtgggta aattgacccg tgcccagttg gaagaaattg
     1441 ctaaaactaa agatcctgat ttgactgctg ctgacttgga tgcggctgtc cgtactatag
     1501 caggttctgc tcgctcaatg ggcttggatg tggagggtgt tgtataatgg ctaaagtatc
     1561 taaacgcttg aaagctcttc gctcttctgt ggaagccaat aaattatatg caattgatga
     1621 agcaattgct ttggtaaaaa aagcagcgac tgctaaattt gacgagtctg ttgacgtatc
     1681 tttcaacttg ggcgttgatc cgcgtaaatc tgaccaagtt atccgtggat cggtcgttct
     1741 gcctaaaggc accggtaaga taacccgtgt ggctgtattt actcaaggtg caaatgcaga
     1801 agctgctaaa gaagctggtg cagatatcgt cggtttcgaa gatttggctg ctgaaatcaa
     1861 agcaggcaat ctgaactttg acgttgttat tgcttctccc gatgcaatgc gtattgttgg
     1921 tcaattgggt accatcttgg gtcctcgtgg tctgatgcca aaccctaaag taggtacggt
     1981 tacccctaat gttgccgaag cagtaaaaaa tgcaaaagca ggtcaagtgc agtaccgtac
     2041 cgacaaggca ggtattgttc atgcaacgat tggtcgtgct tcattcgctg aagctgattt
     2101 gaaagagaac tttgatgcgt tgctggatgc tatcgttaaa gccaagcctg ctgccgctaa
     2161 aggtcagtat ctgaaaaaag ttgctgtgtc tagcaccatg ggtttgggta ttcgcgttga
     2221 tacatcaagc gtaaataact aatcttaagg aattttcaag cagtttggtt ttctgggctg
     2281 cttgaatttg ggctacttaa aattaagtag atgtccaaga ccgtagggat cgtaagattt
     2341 aatcgtaact gccctacgca gacggtagtc ctgaaacaca ttgcaagatt gcttgtaaga
     2401 tgtcttttta ggttaccgcg ctggtgggat atcgttttgg tatcctgttt ataaacagtg
     2461 ggaggtagac cttgagtctc aatattgaaa ccaagaaagt ggcggtcgag gaaattagcg
     2521 cggcaattgc taatgctcaa accctcgtag tcgctgaata tcgcggtatc agtgtttcca
     2581 gtatgactga gcttcgtgcg aatgcacgta aagaaggcgt ttatttgcgc gttctgaaaa
     2641 atactttggc tcgtcgtgca gtgcaaggta cttcatttgc agaattggcc gatcaaatgg
     2701 ttggtccgtt ggtttacgct gcttctgaag atgctgttgc tgctgctaaa gtgttgcacc
     2761 aattcgcgaa aaaagatgac aaaattgtcg ttaaagccgg ttcttacaat ggcgaagtaa
     2821 tgaatgctgc tcaggttgct gagttggctt ctattccgag ccgcgaagag ctgttgtcca
     2881 aactgttgtt cgttatgcaa gctcctgtat cgggctttgc gcgcggtttg gctgctttgg
     2941 cagagaaaaa agccggcgaa gaagccgctt aatcgatttt gtttctgtta atcaattatt
     3001 ttttaataca atatttggag taaaatagca tggctattac taaagaagac attttggaag
     3061 cagttggttc tttgaccgta atggaattga acgacttggt taaagctttt gaagaaaaat
     3121 tcggtgtttc tgctgctgct gttgcagttg caggtcctgc tggtgccggt gctgccgatg
     3181 ctgaagaaaa aaccgaattt gatgtcgttt tggcttctgc cggcgatcaa aaagtcggcg
     3241 tgattaaagt tgtccgtgca attaccggtt tgggtctgaa agaagctaaa gacatcgttg
     3301 acggcgcacc taaaaccatt aaagagggtg tttctaaagc tgaagccgaa gacatccaaa
     3361 aacaactgga agaagccggc gctaaagtcg aaatcaaata atttgatgct tcttatgaag
     3421 gctggcagtt ttctgccagc cttattttgc ttcttaaaat aagcattaag tattgtttac
     3481 atttatttgc atagttttta tcaaatcatt gcaaataaat gtaaacatca gattgatgcg
     3541 tgccgttgct ttcagacggc ctattattga aaattacttt tcggagtgta tatgagctat
     3601 tcgtttaccg agaaaaaacg tatccgtaag agttttgcaa agcgggaaaa tgttttggaa
     3661 gttcctttct tgctggcaac ccaaattgat tcttatgcga agtttttgca gctggaaaat
     3721 gcttttgaca aacgtaccga tgacggtctg caggcggcat ttaattctat tttcccgatt
     3781 gtgagccata acggttatgc gcgattggag tttgtgcatt acacattggg cgagcctttg
     3841 ttcgatattc ccgaatgtca gttgcgcgga atcacttatg cagccccctt gcgcgcgcgt
     3901 atccgtttgg tgattttgga taaggaagca tctaaaccga cggtaaaaga agttcgtgaa
     3961 aacgaagtgt atatgggcga aattccgttg atgaccccga gcggttcttt tgtgattaac
     4021 ggcacagagc gtgtgattgt ctcccagttg caccgttcgc ccggcgtatt cttcgagcat
     4081 gacaaaggta agacgcactc ttccggcaaa ttgttattct ccgcccgcat cattccctac
     4141 cgtggttcat ggttggattt tgaatttgat ccgaaagatt tgctgtattt ccgtatcgac
     4201 cgccgccgta aaatgccggt aacgattttg ttgaaggctt taggctacaa caatgagcaa
     4261 atcttggata ttttctacga caaagaaacg ttctatttgt cttcaaacgg tgttcaaacc
     4321 gatttggtcg cagaccgtct gaaaggcgaa actgccaagg tcgatatctt ggataaagaa
     4381 ggcaatgtat tggttgccaa aggtaagcgc attactgcga aaaatatccg tgatattacc
     4441 aatgcaggcc tgacccgttt ggatgtagaa ccggaaagcc tgctgggcaa agcattggct
     4501 gccgatctga ttgattcgga aaccggcgag gtattggctt ctgccaatga tgaaattaca
     4561 gaagagttgt tggccaaatt tgatatcaac ggcgtaaaag aaattacgac cctttatatc
     4621 aatgagctgg atcagggtgc ttatatctcc aataccttgc gtacggatga gactgccggc
     4681 cggcaggcgg ctcgtgttgc gatttaccgt atgatgcgtc cgggcgaacc gcccaccgaa
     4741 gaggcggtcg agcaattgtt taaccgcttg ttcttcagtg aagacagcta cgatctgtcc
     4801 cgcgtaggcc gtatgaaatt taatacgcgc acatacgaac aaaaactgtc cgaagcccaa
     4861 caaaactctt ggtacggccg cctgctgaac gaaacgtttg ccggtgctgc cgacaaaggc
     4921 ggttatgtcc tgagcgtcga agatattgtc gcctcgattg cgactttggt cgagttgcgt
     4981 aacggccatg gcgaagtgga cgatatcgat cacttgggca accgccgagt acgttcggta
     5041 ggcgagctga ctgaaaacca attccgtagc ggtttggccc gtgtggaacg tgccgtaaaa
     5101 gaacgtttga atcaggcgga atcagaaaac ttgatgccgc acgatttgat taatgcaaaa
     5161 cctgtttctg ccgctattaa agaattcttc ggctccagcc aattgagtca gtttatggat
     5221 cagaccaatc ccttgtctga agtaacccat aaacgccgcg tatccgcatt gggtccgggc
     5281 ggtttgaccc gcgaacgtgc aggatttgag gtgcgggacg tgcatccgac ccactacggt
     5341 cgcgtatgtc cgattgaaac gcctgaaggt ccgaacatcg gtttgatcaa ctcattgtcc
     5401 gtttatgcgc gcaccaatga ttacggtttc ttggaaacgc cttaccgccg cgttatcgac
     5461 ggcaaagtaa ccgaggaaat cgattacttg tctgccatcg aagaaggccg ctatgtgatt
     5521 gcacaggcga atgccgattt ggattcagat ggcaatctga ttggcgattt ggttacctgt
     5581 cgtgaaaaag gcgaaaccat tatggcaacg cccgaccgcg tccaatatat ggacgtggca
     5641 actggtcaag tggtatccgt tgcagcatcc ctgattccgt tcttggaaca tgatgacgcg
     5701 aaccgcgcat tgatgggtgc caacatgcaa cgtcaggcag tgccttgctt gcgtcctgaa
     5761 aaaccgatgg tcggtaccgg tatcgagcgt tccgttgccg ttgactctgc tactgcaatc
     5821 gttgcccgcc gaggcggcgt ggtcgagtat gtcgatgcca accgtgttgt gattcgtgtc
     5881 catgacgacg aagcgactgc cggcgaagtg ggtgtcgata tttacaactt ggttaaattt
     5941 acccgttcca atcaatctac taacatcaac caacgtccgg ctgtcaaagc aggcgatgtt
     6001 ttgcaacgcg gcgatttggt ggccgatggc gcgtccaccg atttgggcga attggctttg
     6061 ggtcaaaata tgaccatcgc cttcatgccg tggaacggtt acaactacga agactcgatt
     6121 ctgatttccg aaaaagtggc tgcggacgac cgctatactt cgattcacat tgaggaattg
     6181 aatgtcgttg cccgcgatac caagctgggt gcggaagaca ttacccgcga tattccgaac
     6241 ttgtccgagc gtatgcaaaa ccgtttggac gaatccggta tcgtttacat cggtgcggaa
     6301 gtagaagccg gcgatgtgtt ggtaggcaag gtaacgccta aaggcgaaac ccagctgacg
     6361 ccggaagaaa aactgctgcg cgccatcttc ggtgaaaaag catctgacgt aaaagatact
     6421 tcattgcgta tgcctaccgg catgagcggt accgttatcg acgttcaagt cttcactcgt
     6481 gaaggtattc aacgcgacaa acgtgctcaa tccattatcg attccgagtt gaaacgctac
     6541 cgtttggatt tgaacgacca attgcgtatt ttcgacaacg acgcattcga ccgtatcgag
     6601 cgtatgattg tcggtcagaa agccaacggc ggcccgatga agctggccaa aggcagtgaa
     6661 atcacgaccg aatatctggc gggtctgccg agcaggcacg attggttcga tatccgtctg
     6721 accgatgaag atttggccaa gcagttggaa ctgattaaag tgagcctgca acaaaaacgc
     6781 gaagaagcgg acgagttata cgaaatcaag aagaaaaaac tgacccaagg cgacgaattg
     6841 caacccggcg tacaaaaaat ggtgaaagtt tttatcgcca tcaaacgccg tctgcaagcc
     6901 ggcgacaaaa tggcgggccg ccacggtaac aaaggcgtgg tatcgcgcat tctgccagtg
     6961 gaagacatgc cttacatggc ggacggccgt ccggtagaca tcgtactgaa cccattgggc
     7021 gtaccttccc gtatgaacat cggtcagatt ttggaagttc acttgggttg ggcagcaaaa
     7081 ggtatcggcg agcgtatcga ccgtatgctg aaagagcaac gcaaagcagg cgagttgcgc
     7141 gagttcttga acagactcta caacggcagc ggcaagaaag aagatttgga tgccctgact
     7201 gatgaagaaa tcatcgaact ggcctccaac ctgcgtaaag gtgcatcttt cgcctctcct
     7261 gtattcgacg gtgcgaaaga gtctgaaatc cgcgaaatgt tgaacttggc ttatccgagc
     7321 gacgatcctg aggttgaaaa actgggcttc aacgacagta aaacccaaat cacgctgtat
     7381 gacggccgtt caggcgaagc atttgaccgc aaggttacag taggtgtgat gcactatctg
     7441 aaactgcacc acttggttga cgaaaaaatg cacgcgcgtt ctaccggtcc atacagtctg
     7501 gttacccaac agcctttggg cggtaaagct cagttcggtg gccaacgttt cggtgagatg
     7561 gaggtttggg cattggaagc atacggtgcg gcatacacgc tgcaagagat gctgactgtg
     7621 aagtctgatg acgtgaacgg ccgtaccaaa atgtacgaga acatcgtcaa aggcgaacac
     7681 aaaatcgatg ccggtatgcc cgagtccttc aacgtattgg ttaaagagat tcgttcactg
     7741 ggcttggata tcgatttgga acgctactaa gcagaagttt tcagacggcc tttcaaggtc
     7801 gtctgaaaaa gcggtttcag aataagaatg aagcaatcgg catttaggcc gtctgaaatc
     7861 gaaagtaccg tttcccaata tcgaaaatcc gccacgcggt aaaaatactt ccttcaagga
     7921 gcaaaaatga atttgttgaa cttatttaat ccgttgcaaa ctgccggcat ggaagaagag
     7981 tttgatgcca tcaaaatcgg cattgcttct cccgaaacca tccgttcatg gtcttacggc
     8041 gaagttaaaa aacctgaaac catcaactac cgtacgttca aacctgagcg tgacggtctg
     8101 ttctgcgcca aaatctttgg tccggtcaaa gactacgaat gcttgtgcgg aaaatacaaa
     8161 cgcttgaaat ttaaaggcgt aacctgtgaa aaatgcggcg tagaagtgac cctgtccaaa
     8221 gtgcgccgcg aacgcatggg ccacattgaa ttggcagcac ccgttgccca tatttggttc
     8281 ttgaaatccc tgccttcccg cttgggtatg gtactggaca tgactttgcg cgacatcgaa
     8341 cgcgtattgt actttgaagc atttgtggta accgaccccg gtatgactcc gctgcaacgc
     8401 cgccaattgc tgactgaaga cgattactac aacaaactgg acgaatacgg cgatgacttc
     8461 gatgccaaaa tgggtgcgga aggtatccgc gaattgctgc gtaccttgaa tgtggcgggc
     8521 gaaatcgaaa tcctgcgcca agagttggaa tcgaccgggt ccgacaccaa aatcaaaaaa
     8581 atcgccaaac gtttgaaagt attggaagcc ttccaccgtt ccggtatgaa gctggaatgg
     8641 atgattatgg atgtgctgcc ggtattgccg cctgatttgc gtccgttggt tccattggat
     8701 ggcggtcgtt ttgccacttc cgatttgaac gatttgtacc gtcgcgtcat caaccgtaac
     8761 aaccgtctga aacgtctgtt ggaactgcat gcgcccgaca ttatcgtccg caacgaaaaa
     8821 cgtatgttgc aagaagcggt cgactctctg ttggataacg gccgtcgcgg taaagccatg
     8881 accggcgcca acaaacgccc gctgaaatca ttggcagaca tgattaaagg taaaggcggt
     8941 cgcttccgtc aaaacctgtt gggcaaacgt gtggactact ccggccgttc cgtgattacc
     9001 gtaggcccat acctgcgtct gcaccaatgc ggtctgccga aaaaaatggc tttggaactg
     9061 ttcaaaccgt tcattttcca caaattggaa aaacaaggtt tggcctctac cgttaaagca
     9121 gcgaaaaaat tggtagagca agaagtaccg gaagtatggg acatcttgga agaagtcatc
     9181 cgcgaacatc cgattatgct gaaccgtgcg ccgaccctgc accgtttggg tattcaagcg
     9241 ttcgaaccta tcttgattga aggtaaagcg attcagttgc acccattggt gtgtgctgcg
     9301 ttcaacgccg actttgacgg cgaccaaatg gcggtacacg ttccattgag cttggaagca
     9361 caaatggaag cacgcacgct gatgctggct tcaaacaacg tattgtctcc tgccaacggc
     9421 gaaccgatta tcgtaccttc ccaagacatc gtattgggcc tgtactacat gacccgcgac
     9481 cgtatcaatg ccaaaggcga gggcagcctg tttgccgatg tgaaagaagt gcatcgcgca
     9541 taccatacca aacaggttga actgggtacg aaaattaccg tacgtctgcg cgaatgggtg
     9601 aaaaacgaag caggtgagtt tgagcctgtc gttaaccgtt acgaaacaac cgtcggccgt
     9661 gcattgttga gcgaaatcct gccgaaaggc ctgccgtttg aatatgtcaa caaagcgttg
     9721 aagaaaaaag aaatttctaa actgattaac gcatcgttcc gcctgtgcgg cttgcgcgat
     9781 acggttatct ttgctgacca cctgatgtac accggtttcg gatttgcggc aaaaggcggt
     9841 atttccattg ccgttgacga tatggaaatt ccaaaagaaa aagtggcctt gctggctgaa
     9901 gccaatgccg aggttaaaga aatcgaagac caataccgtc aaggtttggt taccaacggc
     9961 gaacgctaca acaaggtggt cgatatttgg ggtcgtgccg gcgataagat tgctaaagcg
    10021 atgatggaca acttgtccaa acaaaaagtt atcgaccgtg acggcaacga agtcgatcaa
    10081 gagtcattca actccattta tatgatggcg gactccggtg cccgtggttc tgcagctcag
    10141 attaaacagt tgtccggtat gcgtggcttg atggcaaaac ctgacggctc gattattgaa
    10201 acgccgatta cctcaaactt ccgtgaaggt ctgaccgtat tgcaatactt tattgcgacc
    10261 cacggtgcgc gtaagggttt ggcggatacc gcattgaaaa ccgcgaactc cggttacctg
    10321 acccgtcgtc tggtagacgt aactcaagat ttggtcgttg ttgaagacga ttgcggtact
    10381 tcagacggct ttgtcatgaa ggcagtggta caaggcggtg atgtgattga agcattgcgc
    10441 gagcgtattt tgggccgtgt tactgcgtct gacgttgtcg atccgtcaag cggcgagacc
    10501 ttggttgaag caggcacgtt gttgactgaa aaactggtgg atatgattga ccaatccggt
    10561 gtcgatgaag tcaaagtccg tactccgatt acttgtaaaa cccgccacgg tttgtgcgcg
    10621 cactgttacg gccgcgactt ggcgcgcggc aaactggtca atgccggaga ggcagtcggc
    10681 gtgattgccg cccaatcaat cggcgaaccg ggtacccagc tgactatgcg tacgttccac
    10741 atcggtggtg cggcatcccg tgcggcagca gccagccaag tggaagccaa atccaacggt
    10801 acggcacgat tcagcagcca aatgcgttat gttgccaaca ataaaggcga gttggttgtc
    10861 atcggccgtt cttgtgaagt cgtgattcac gatgacatcg gccgtgaacg cgaacgccac
    10921 aaagtacctt acggtgccat cctgctggta caagacggta tggccattaa agccggtcaa
    10981 accttggcaa cctgggatcc gcatacccgt ccgatgatta ccgaacacgc aggtatggtg
    11041 aaattcgaaa acgtggaaga gggcgttacc gttgccaaac aaaccgatga tgtaaccggt
    11101 ttgtccactt tggtagtgat cgacggtaaa cgtcgttcct ctagtgcttc caaactgctg
    11161 cgtccgactg tgaaactctt ggacgaaaac ggcgtggaaa tctgtattcc cggtacttct
    11221 actccggtat ccatggcatt ccccgttggt gcggtgatta ccgtacgcga aggtcaggaa
    11281 atcggtaaag gcgacgtatt ggcgcgtatc ccgcaagcct cttccaaaac ccgcgacatt
    11341 accggtggtc tgccgcgcgt tgccgaattg tttgaagcac gcgtgccgaa agatgccggt
    11401 atgttggcgg aaattaccgg taccgtttcc ttcggcaaag agaccaaagg caagcaacgt
    11461 ctgattatta ccgacgtgga cggcgtagca tacgagactt tgatttccaa agagaaacag
    11521 attttggtac acgacggtca agtggtaaac cgcggcgaaa ccattgtgga cggcgcggtc
    11581 gatccgcacg atattctgcg tctgcaaggt atcgaagcac tggcacgcta cattgtccaa
    11641 gaggtgcaag aggtttaccg tctgcaaggt gtgaagattt ccgacaaaca catcgaagtc
    11701 atcatccgtc aaatgttgcg ccgtgtgaac attgcggatg ccggcgaaac cggcttcatt
    11761 accggcgagc aggtcgaacg cggcgatgtg atggctgcca atgaaaaagc tttggaagaa
    11821 ggcaaagaac cggcacgtta cgaaaacgta ttgctgggta ttaccaaagc ctccctgtct
    11881 accgacagct tcatttctgc cgcatcgttc caagaaacga cccgcgttct gaccgaagcc
    11941 gcgattatgg gcaaacaaga cgagctgcgc ggtctgaaag agaacgtgat tgtcggtcgt
    12001 ttgattcctg ctggtactgg tttgacttac caccgcagcc gtcatcaaca atggcaagag
    12061 gtggagcagg agactgctga aacccaagta acggatgaat aatctttggt gcgtttattc
    12121 aatacaaaac cgcaagcttt aggcttgtgg tttttctttc agacggcatt taaattatta
    12181 gtgatttcct ttccggtaat agttgtttat gagcataagg gacctaaatg tttatctgaa
    12241 aaaagaaaaa tgatgaatct tcctgatctc acgcttgact gtctgcttgc aataaaaata
    12301 taattccact cttgccgaca tggtgtcggc aagtatttaa ctcaacagga cgagaaaata
    12361 tgccaactat caaccaattg gtacgcaaag gccgtcaaaa gcccgtgtac gtaaacaaag
    12421 tgcccgcact ggaagcctgc ccgcaaaaac gcggcgtgtg cacccgtgta tacacgacta
    12481 cccctaaaaa acctaactct gcattgcgta aagtatgtaa agtccgcctg accaacggtt
    12541 ttgaagtcat ttcatacatc ggcggcgaag gccacaacct gcaagagcac agtgtcgtat
    12601 tgattcgcgg cggtcgtgta aaagacttgc caggtgtgcg ttaccacact gtacgcggtt
    12661 ctttggatac tgcaggtgtt aaagaccgta aacaagcccg ttccaaatat ggtgctaagc
    12721 gtcctaaata attactggga cttaaatagg cacgtcggcc gcctaagcag aacaacggcc
    12781 gagtaagtga atactcaatt gggtattcat gggaatagac ccgactgaat agattaaagg
    12841 aaattaaaat gccaagacgt agagaagtcc ccaagcgcga cgtactgcca gatcctaaat
    12901 tcggcagcgt cgagttgacc aaattcatga acgtattgat gattgacggt aaaaaatccg
    12961 ttgccgagcg tatcgtttac ggtgcgttgg aacagattga gaaaaaaacc ggcaaagtag
    13021 caatcgaagt atttaacgaa gccattgcaa acgccaaacc tatcgtggaa gtgaaaagcc
    13081 gccgtgtagg tggtgcaaac taccaagttc ctgttgaagt tcgtccttca cgccgtttgg
    13141 ctttggcaat gcgctgggtt cgcgatgcgg cccgcaaacg tggtgagaaa tccatggacc
    13201 tgcgtttggc aggcgaattg attgatgcgt ccgaaggccg tggcggtgcg ttgaaaaaac
    13261 gtgaagaagt acaccgtatg gctgaagcca acaaagcatt ctctcacttc cgtttctaat
    13321 tttgaaaggc taataaaatg gctcgtaaga ccccgatcag cctgtaccgt aacatcggta
    13381 tttccgccca tatcgatgcg ggtaaaacca cgacgacaga acgtattttg ttctataccg
    13441 gtttgaccca caagctgggc gaagtgcatg acggtgcggc tactaccgac tacatggaac
    13501 aagagcaaga gcgcggtatt accattacct ccgctgccgt tacttcctac tggtccggta
    13561 tggcgaaaca attccccgag caccgcttca acatcatcga caccccggga cacgttgact
    13621 ttaccgtaga ggtagagcgt tctatgcgtg tattggacgg cgcggtaatg gtttactgcg
    13681 cggtgggcgg tgttcaaccc caatctgaaa ccgtatggcg gcaagccaac aaataccaag
    13741 tgccgcgctt ggcgtttgtc aataaaatgg accgtcaggg tgccaacttc ttccgcgttg
    13801 tcgagcaaat gaaaacccgt ttgcgcgcaa accctgtacc tatcgtcatt ccggttggtg
    13861 cggaagacaa cttcagcggt gtggttgatt tgttgaaaat gaaatccatc atttggaatg
    13921 aagccgataa aggtacaacc tttacctatg gcgatattcc tgccgaattg gtcgaaactg
    13981 ccgaagaatg gcgtcaaaat atgattgaag ccgcagccga agccagcgaa gaactgatgg
    14041 acaaatactt aggcggcgac gagctgaccg aagaagaaat cgtaggcgcg ttgcgtcaac
    14101 gtactttggc aggcgaaatt cagcctatgc tgtgtggttc tgcatttaaa aacaaaggtg
    14161 ttcaacgtat gttggacgca gttgtagaat tgctgccagc tcctaccgat attcctccgg
    14221 ttcaaggtgt caacccgaat accgaggaag ccgacagccg tcaagccagc gatgaagaga
    14281 aattctctgc attggcgttc aaaatgttga acgacaaata cgtcggtcag ctgaccttta
    14341 tccgcgttta ctcaggcgta gtaaaatccg gcgataccgt attgaactcc gtaaaaggca
    14401 ctcgcgaacg tatcggtcgt ttggtacaaa tgactgccgc agaccgtact gaaatcgaag
    14461 aagtacgcgc cggcgacatc gcagccgcta ttggtctgaa agacgttact accggtgaaa
    14521 ccttgtgtgc ggaaagcgcg ccgattatct tggaacgtat ggaattcccc gagccggtaa
    14581 tccatattgc cgttgagccg aaaaccaaag ccgaccaaga gaaaatgggt atcgccctga
    14641 accgcttggc taaagaagac ccttctttcc gtgtccgtac agacgaagaa tccggtcaaa
    14701 ccattatttc cggtatgggt gagctgcact tggaaattat tgttgaccgt atgaaacgcg
    14761 aattcggtgt ggaagcaaat atcggtgcgc ctcaagtggc ttaccgtgaa actatccgca
    14821 aagccgttaa agccgaatac aaacatgcaa aacaatccgg tggtaaaggt caatacggtc
    14881 acgttgtgat tgaaatggaa cctatggaac cgggtggtga aggttacgag tttatcgatg
    14941 aaattaaagg tggtgtgatt cctcgcgaat ttattccgtc tgtcgataaa ggtatccgcg
    15001 atacgttgcc taacggtatc gttgccggct atcctgtagt tgacgtacgt atccgtctgg
    15061 tattcggttc ttaccatgat gtcgactctt cccaattggc atttgaattg gctgcttctc
    15121 aagcgtttaa agaaggtatg cgtcaagcat ctcccgccct gcttgagccg attatggcag
    15181 ttgaagtgga aaccccggaa gaatacatgg gcgacgtaat gggcgacttg aaccgccgtc
    15241 gcggtgttgt attgggtatg gatgatgacg gtatcggcgg taaaaaagtc cgtgccgaag
    15301 tacctctggc agaaatgttc ggttactcga ccgacctgcg ttctgcaacc caaggccgcg
    15361 ctacttactc tatggagttc aagaaatatt ctgaagctcc tgctcacata gctgctgctg
    15421 taactgaagc ccgtaaaggc taatcaggca aataggccgt ccgaaaggct gaaatgattt
    15481 ttcagacggc attgttcttt aatcgatctt taatgtaaag gaattagc
//
LOCUS       DAXIDM010000044        15498 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000044 DAXIDM010000000
VERSION     DAXIDM010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 15498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15498
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.044"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..460)
                     /locus_tag="ACFOAE_001131"
     CDS             complement(<1..460)
                     /locus_tag="ACFOAE_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6884630.1"
                     /translation="MSTFFRQTAQAMIAKHINRFPLLKLDQVIDWQPIEQYLNRQKTR
                     YLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNWLAQDDTLSELLELINRQLTEKGLKIEKASAAVVDATIIQTAGS"
     gene            632..2041
                     /gene="murC"
                     /locus_tag="ACFOAE_001132"
     CDS             632..2041
                     /gene="murC"
                     /locus_tag="ACFOAE_001132"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFC6884631.1"
                     /translation="MMKNRVTNIHFVGIGGVGMSGIAEVLHNLGFKVSGSDQARNAAT
                     EHLGSLGIQVYPGHTAEHVNGADVVVTSTAVKKENPEVVAALEQQIPVIPRALMLAEL
                     MRFRDGIAIAGTHGKTTTTSLTASILGAAGLDPTFVIGGKLNAAGTNARLGKGEYIVA
                     EADESDASFLHLTPIMSVVTNIDEDHMDTYGHSVEKLHQAFIDFIHRMPFYGKAFLCI
                     DSEHVRAILPKVSKPYATYGLDDTADIYATDIENVGAQMKFTVHVQMKGHEQGSFEVV
                     LNMPGRHNVLNALAAIGVALEVGASVEAIQKGLLGFEGVGRRFQKYGDIKLPNGGTAL
                     LVDDYGHHPVEMAATLSAARGAYPEKRLVLAFQPHRYTRTRDLFEDFTKVLNTVDALV
                     LTEVYAAGEEPIAAADSRALARAIRVLGKLEPIYCENVADLPEMLLNVLQDGDIVLNM
                     GAGSINRVPAALLELSKQI"
     gene            2154..3068
                     /locus_tag="ACFOAE_001133"
     CDS             2154..3068
                     /locus_tag="ACFOAE_001133"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003764621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFC6884632.1"
                     /translation="MQNFGKVAVLMGGFSSEREISLDSGTAILNALKSKGIDAYAFDP
                     KETPLSELKAQGFQTAFNILHGTYGEDGAVQGALELLGIPYTGSGVAASAIGMDKYRC
                     KLIWQALGLPVPEFAVLHDDTDFDAVEEKLGLPMFVKPAAEGSSVGVVKVKEKGRLKS
                     VYEELKHLQGEIIAERFIGGGEYSCPVLNGKGLPGIHIIPATEFYDYEAKYNRNDTIY
                     QCPSEDLTEAEESLMRELAVRGAQAIGAEGCVRVDFLKDTDGKLYLLEINTLPGMTSH
                     SLVPKSAAVTGVGFADLCIEILKTAHVG"
     gene            3058..3786
                     /locus_tag="ACFOAE_001134"
     CDS             3058..3786
                     /locus_tag="ACFOAE_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFC6884633.1"
                     /translation="MWDNAEAMERLTRWLLVMMAMLLAASGLVWFYNSNHLPVKQVSL
                     KGNLVYSDKKTLGSLAKEYIHGNILRTDINGAQEAYRRYPWIASVMVRRRFPDTVEVV
                     LTERKPVARWGDHALVDGEGNVFEARLDRPGMPVFRGAEGTSAEMLRRYDEFSTVLAK
                     QGLGIKEMTYTARSAWIVVLDNGITVRLGRENEMKRLRLFTEAWQHLLRKNKNRLSYV
                     DMRYKDGFSVRYASDGLPEKESEE"
     gene            3872..5116
                     /gene="ftsA"
                     /locus_tag="ACFOAE_001135"
     CDS             3872..5116
                     /gene="ftsA"
                     /locus_tag="ACFOAE_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFC6884634.1"
                     /translation="MEQQQRYISVLDIGTSKVLALIGEVQDDDKINIVGLGQAPSRGL
                     RAGMVTNIDATVQAIRQAVNDAELMADTKITHVTTGIAGNHIRSLNSQGVVKIKDGEV
                     TQADIDRAIETAKAINIPPDQKILDAVVQDYIIDTQLGVREPIGMSGVRLDTRVHIIT
                     GASTAVQNVQKCIERCGLKSDQIMLQPLASGQAVLTEDEKDLGVCVIDIGGGTTDIAV
                     YMNGAIRHTSVIPAGGNLITKDLSKSLRTPLDAAEYIKIHYGVASCDTEGLGEMIEVP
                     GVGDRTSRQVSSKVLAAIISARIQEIFGVVLGELQKSGFPKEVLNAGIVLTGGVSMMT
                     GIVEFAEKIFDLPVRTGAPQEMGGLSDRVRTPRFSTAIGLLHAACKLEGNLPQPENGA
                     VQEREVGGGLLARLKRWIENSF"
     gene            5235..6413
                     /gene="ftsZ"
                     /locus_tag="ACFOAE_001136"
     CDS             5235..6413
                     /gene="ftsZ"
                     /locus_tag="ACFOAE_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFC6884635.1"
                     /translation="MEFVYDVAESAVSPAVIKVIGLGGGGCNAINNMVANNVRGVEFI
                     SANTDAQSLAKNHAAKRIQLGTNLTRGLGAGANPDIGRAAAQEDREAIEEAIRGANML
                     FITTGMGGGTGTGSAPVVAEIAKSLGILTVAVVTRPFAYEGKRVHVAQAGLEQLKEHV
                     DSLIIIPNDKLMTALGEDVTMREAFRAADNVLRDAVAGISEVVTCPSEIINLDFADVK
                     TVMSNRGIAMMGSGYAQGIDRARMATDQAISSPLLDDVTLDGARGVLVNITTAPGCLK
                     MSELSEVMKIVNQSAHPDLECKFGAAEDETMSEDAIRITIIATGLKEKGAVGFVPARE
                     VEAVAPSKQEQSHNVEGMIRTNRGIRTMNLTAADFDNQSVLDDFEIPAILRRQHNSDK
                     "
     gene            6552..7862
                     /locus_tag="ACFOAE_001137"
     CDS             6552..7862
                     /locus_tag="ACFOAE_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFC6884636.1"
                     /translation="MDTSKQTLLDGIFKLKANGTTVRTELMAGLTTFLTMCYIVIVNP
                     LILGETGMDMGAVFVATCIASAIGCFVMGFVGNYPIALAPGMGLNAYFTFAVVKGMGV
                     PWQVALGAVFISGLIFILFSFFKVREMLVNALPMGLKMSIAAGIGLFLALISLKGAGI
                     IVANPATLVGLGDIHQPSALLALFGFAMVVVLGHFRVQGAIIITILTITVIASLMGLN
                     EFHGIIGEVPSIAPTFMQMDFEGLFTVSMVSVIFVFFLVDLFDSTGTLVGISHRAGLL
                     VDGKLPRLKRALLADSTAIVAGAALGTSSTTPYVESAAGVSAGGRTGLTAVTVGVLML
                     ACLMFSPLAKSVPAFATAPALLYVGTQMLRSARDIDWDDMTEAAPAFLTIVFMPFTYS
                     IADGIAFGFISYAVVKLLCRRTKDVPPMVWIVAVLWALKFWYLG"
     gene            8488..9363
                     /gene="prpB"
                     /locus_tag="ACFOAE_001138"
     CDS             8488..9363
                     /gene="prpB"
                     /locus_tag="ACFOAE_001138"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003779818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046421 - methylisocitrate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HFC6884637.1"
                     /translation="MSQHSAGARFRQAVKESNPLAVAGCVNAYFARLATQSGFKAIYL
                     SGGGVAACSCGIPDLGITTMEDVLIDARRITDNVDTPLLVDIDVGWGGAFNIARTIRN
                     FERAGVAAVHIEDQVAQKRCGHRPNKAIVSKDEMVDRIKAAVDARVDENFVIMARTDA
                     LAVEGLDAAIERAQACVEAGADMIFPEAMTDLNMYRQFADAVKVPVLANITEFGSTPL
                     YTQSELAENGVSLVLYPLSSFRAASKAALNVYEAIMRDGTQAAVVDSMQTRAELYEHL
                     NYHAFEQKLDKLFQK"
     gene            9448..10602
                     /gene="prpC"
                     /locus_tag="ACFOAE_001139"
     CDS             9448..10602
                     /gene="prpC"
                     /locus_tag="ACFOAE_001139"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050440 - 2-methylcitrate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HFC6884638.1"
                     /translation="MTETTQTPTFKPKKSVALSGVAAGNTALCTVGRTGNDLSYRGYD
                     ILDLAQKCEFEEVAHLLIHGHLPNKFELAAYKAKLKSMRGLPIRVIKVLESLPAHTHP
                     MDVMRTGVSMLGCVHPERESHPESEARDIADKLIASLGSILLYWYQYSHNGKRIEVES
                     DEETIGGHFLQLLHGKRPSESHIKAMHVSLILYAEHEFNASTFTARVIAGTGSDMYSS
                     ITGAIGALKGPKHGGANEVAYDIQKRYRNADEAEADIRERIGRKEIVIGFGHPVYTIS
                     DPRNVVIKEVARGLSKETGDMRLFDIAERLESVMWEEKKMFPNLDWFSAVSYQKLGVP
                     TAMFTPLFVISRTTGWSAHVLEQRKDGKIIRPSANYTGPEDLAFVEIEER"
     gene            10695..11417
                     /locus_tag="ACFOAE_001140"
     CDS             10695..11417
                     /locus_tag="ACFOAE_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HFC6884639.1"
                     /translation="MDKDKGSYAGIPVQNTKELVWQKIQDIPISECGEPLVSVGNTGR
                     IRVNPVYFSQGIEGAINSVLLRRSVADRLTQVVSLLPEVYGLEIFDGWRPVIVQRALR
                     ENMKQEIEKRHPEYDEVQVREALDCFAADPDRAGMPLPHLTGGSVDVGLFDIKSGKSL
                     DMGSEFDATGHLSYSDALEKEGEYFSSARNLRRILIHAMKEAGFSNLPTEWWHFDYGN
                     QNWAYFTQQSNAVFGAVEEQDT"
     gene            11443..12648
                     /locus_tag="ACFOAE_001141"
     CDS             11443..12648
                     /locus_tag="ACFOAE_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HFC6884640.1"
                     /translation="MQTLISADNHLLLWAFVMLAAAAAIFIEQNSRLAGKVPGAVLAL
                     LIALIASNLGVIPTDAPVFDAVWSYIVPLAIPLLLFQLDLHALFKESGRMLFIFLISS
                     LGTVIGTLVSFALLKNYIPELDKVAGMISASYTGGGVNFAAMSAKLNPAKDVIAATIV
                     ADNLMMACYFFILIGISSSYWVRKVWGSPYQDKLEQEYHDPSVNKAAEYWKPKSISLQ
                     SIALSLAASILLVAVSFSLSSFLQNHFQSVDGVALKMLTGLISDKYLLLTTFTLAVVL
                     FFRKGIQKLDGSQELGTYCIYLFFVVIGVPASIPLIIKTAPLLFVFTLIIAVLNLLLT
                     LVLGKLFKFSIEEIVLACNANIGGPTTAAALAISKGWRDLVGAILLIGTVGYIIGNYI
                     GSFVYALLS"
     gene            12751..15357
                     /gene="acnD"
                     /locus_tag="ACFOAE_001142"
     CDS             12751..15357
                     /gene="acnD"
                     /locus_tag="ACFOAE_001142"
                     /EC_number="4.2.1.99"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047456 - 2-methylisocitrate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019679 - propionate metabolic process,
                     methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe/S-dependent 2-methylisocitrate dehydratase
                     AcnD"
                     /protein_id="HFC6884641.1"
                     /translation="MAANQRYRKPLPGTDLEYYDARAACEDIKPGSYDKLPYTSRILA
                     ENLVNRADKVDLPTLQSWLGQLIEGKQEIDFPWYPARVVCHDILGQTALVDLAGLRDA
                     IAEKGGDPAKVNPVVQTQLIVDHSLAVECGGYDPDAFRKNREIEDRRNEDRFHFINWT
                     KTAFENVDVIPAGNGIMHQINLEKMSPVVQVKNGVAFPDTCVGTDSHTPHVDALGVIS
                     VGVGGLEAETVMLGRASMMRLPDIVGVELNGKRKAGITATDIVLALTEFLRKERVVGA
                     FVEFFGEGARSLSIGDRATISNMTPEFGATAAMFAIDEQTIDYLKLTGRDDAQVKLVE
                     TYAKTAGLWADALKTAVYPRVLKFDLSSVTRNMAGPSNPHARFATVDLAAKGLAKPYE
                     EPSDGQMPDGAVIIAAITSCTNTSNPRNVVAAALLARNANRFGLKRKPWVKTSFAPGS
                     KVAEIYLKEAGLLPEMEKLGFGIVAFACTTCNGMSGALDPKIQKEIIDRDLYATAVLS
                     GNRNFDGRVHPYAKQAFLASPPLVVAYALAGSIRFDIENDVLGVADGKEIRLKDIWPA
                     DEEIDAVVAEYVKPQQFRDVYVPMFDTGTAQKAPSPLYDWRPMSTYIRRPPYWEGALA
                     GERTLSGMRPLAILPDNITTDHLSPSNAILASSAAGEYLAKMGLPEEDFNSYATHRGD
                     HLTAQRATFANPKLFNEMVRNEDGSVRQGSLARVEPEGQTMRMWEAIETYMNRKQPLI
                     IIAGADYGQGSSRDWAAKGVRLAGVEAIVAEGFERIHRTNLIGMGVLPLQFKPGTNRH
                     TLQLDGTETYDVVGERKPRCDLTLVIHRKNGETVEVPVTCRLDTAEEVLVYEAGGVLQ
                     RFAQDFLEGNAA"
BASE COUNT         3804 a         3705 c         4140 g         3849 t
ORIGIN      
        1 tgctgccggc ggtctgaata atggtggcgt caacaacggc agcggatgct ttctctattt
       61 ttaaaccttt ttcggtcagt tggcggttga tcagttccaa cagttcggac agggtgtcgt
      121 cttgcgccag ccagttgcgg tagcggcata aggtgctgta atcggggatg ctcagttcgt
      181 caaaacgaca aaacaggttg aaatcgatgc gggtaatgag gctgtgttcg agttcgggat
      241 cggagaggct gtgccattgt ccgagcagga cggctttgaa catggacaac agcgggtagg
      301 cgggacggcc gcggtggtct cgaaggtaac gggttttttg acggttcagg tactgttcga
      361 tcggctgcca atcaatcact tggtccaact tcaatagcgg gaaacggttg atgtgtttgg
      421 caatcatggc ttgcgcggtt tgccggaaga aggtgctcat ggaaaatccc ctaaatgtct
      481 tggtgggaat ttaggggatt ttgggggatt ttgcaaaggt ctcatcctgt atgccgaaac
      541 atctgtaatt tacaagaaaa ctatggcgta gaagcggata gccctttaaa ataacgcctt
      601 tacgcatcga aatccaccgg aacgcaacat tatgatgaaa aatcgagtga ccaacatcca
      661 ttttgtcggt atcggcggcg tcggcatgag cggtatcgcc gaagtcttgc acaatttggg
      721 ttttaaagtt tccggttcgg atcaggcgcg aaatgccgct accgagcatt tgggcagcct
      781 gggcattcaa gtttatcccg gccataccgc agaacacgtt aacggtgcgg atgtcgtcgt
      841 tacctctacc gccgtcaaaa aagaaaatcc cgaagttgtc gctgcgttgg agcagcaaat
      901 tcccgttatt ccgcgcgccc tgatgttggc ggagttgatg cgcttccgtg acggcatcgc
      961 cattgccggc acgcacggca aaaccacgac caccagcctg accgcctcca tcctcggcgc
     1021 ggcaggactt gacccgactt tcgttatcgg cggcaaactc aacgccgcag gcaccaacgc
     1081 ccgcttgggc aaaggcgaat acatcgttgc cgaagccgac gagtcggatg catcctttct
     1141 gcacctgaca ccgattatgt ccgtcgttac caatatcgac gaagaccata tggataccta
     1201 cgggcacagc gtcgaaaaac tgcatcaggc gtttatcgat ttcatccacc gtatgccctt
     1261 ctacggcaaa gcctttttgt gtattgacag cgaacacgtc cgcgcgattt tgcccaaagt
     1321 gagcaaacct tatgctactt acggtttgga cgataccgcc gacatctacg ccaccgacat
     1381 cgaaaacgtc ggcgcgcaaa tgaaattcac cgtccatgtt caaatgaaag gacatgagca
     1441 ggggtcgttt gaagtcgtgc tgaatatgcc cggcagacac aacgtgctga acgcattggc
     1501 agccatcggc gtggcgctgg aagtcggcgc atcggttgaa gcgatccaaa aaggcttgct
     1561 cggctttgaa ggtgtcggcc gccgcttcca aaaatacggc gacatcaagt tgccaaacgg
     1621 cgggaccgcg ctcttggtgg acgactacgg acaccacccc gtcgaaatgg cggcgaccct
     1681 ttccgccgca cgcggcgcgt atccggaaaa acgtttggta ctcgccttcc agccgcaccg
     1741 ctatacccgc acgcgcgatt tgtttgaaga ctttaccaaa gtcctcaata ccgttgacgc
     1801 gctggtgctg accgaagttt atgccgccgg tgaagagccg attgccgccg ccgattcccg
     1861 cgctcttgcc cgcgccatcc gcgtgttggg caaactcgag ccgatttact gcgaaaacgt
     1921 tgccgatctg cccgaaatgc tgttgaacgt tttgcaggac ggcgacatcg tgttgaatat
     1981 gggcgcggga agcatcaacc gcgtccccgc cgcgctgctg gaattgtcga aacagatttg
     2041 aggcacaccc gcctgacaga cggaacatca tataaaggtc gtctgaaacc gcaaatcagg
     2101 tttcagacga cctctggcaa caagcataaa gcaatcagga aagaacaaaa acaatgcaga
     2161 attttggcaa agtggccgta ttgatgggcg gtttttccag cgaacgagaa atctcgctgg
     2221 acagcggcac cgccattttg aatgctttaa aaagcaaagg catagacgca tacgccttcg
     2281 atcctaaaga aaccccattg tctgaattga aggcacaagg ttttcagacg gcattcaaca
     2341 tccttcacgg tacttacggc gaagacgggg cggttcaggg tgcattggaa ctgttgggca
     2401 ttccctatac cggcagcggt gtcgccgcat ccgccatcgg catggacaaa taccgctgca
     2461 aactgatttg gcaggcattg ggattgcccg ttcccgagtt cgccgtcctg cacgacgaca
     2521 ctgatttcga tgccgtcgaa gaaaaattgg gcctgccgat gtttgtgaaa ccggcggccg
     2581 aaggcagcag cgtcggtgtg gtaaaagtca aagaaaaagg ccgtctgaaa agcgtttacg
     2641 aagaattgaa acaccttcag ggcgaaatca ttgccgaacg ttttatcggc ggcggcgaat
     2701 attcctgccc cgtcctgaac ggcaaagggc tgcccggcat acacatcatt cccgcaaccg
     2761 agttttacga ctacgaagcc aagtacaacc gcaacgacac catttatcaa tgtccttcgg
     2821 aagatttgac cgaagccgaa gaaagcctga tgcgcgaact ggcggttcgc ggcgcgcagg
     2881 caatcggtgc ggaaggctgc gtgcgcgtcg atttcctcaa agataccgac ggcaaactct
     2941 atctgttgga aatcaacacc ctgcccggta tgacgagcca tagtttagta ccgaaatccg
     3001 ctgccgttac gggcgtgggt tttgccgatt tatgtattga aattttgaag accgcacatg
     3061 tgggataatg ccgaagcgat ggaacggctg acgcgctggc tgcttgtcat gatggcgatg
     3121 ctgcttgctg cgtccgggct ggtttggttt tacaattcga atcatctgcc cgtcaagcag
     3181 gtgtcgctga agggcaacct ggtttattcc gataagaaga cattgggcag tttggcgaaa
     3241 gaatacatcc atgggaatat tttgaggacg gacatcaatg gcgcacagga agcctaccgc
     3301 cggtatccgt ggattgcgtc ggtcatggtg cgccgccgtt ttcccgatac ggttgaggtc
     3361 gtcctgaccg agcgcaagcc ggtcgcgcgt tggggtgacc atgccttggt ggacggcgaa
     3421 ggcaatgttt ttgaagcccg cttggacaga cccggaatgc cggtattcag aggcgcggaa
     3481 ggaacgtctg ccgaaatgct ccgccgttat gacgaatttt cgactgtttt ggcaaaacag
     3541 ggtttgggca tcaaagagat gacctatacg gcacgttcgg cgtggattgt cgttttggac
     3601 aacggcatca ccgtcaggct cggacgggaa aacgagatga aacgcctccg gctttttacc
     3661 gaagcgtggc agcatctgtt gcgtaaaaat aaaaatcggt tatcctatgt ggatatgagg
     3721 tataaggacg gattttcagt ccgctatgct tccgacggtt tacccgaaaa agaatccgaa
     3781 gaatagtggg aacaggtatc ggacagatta cggccgtgcc gtctgaaacg gtgcgacgca
     3841 aatttcaatc agttttaaga gcagacgaac aatggaacag cagcaaagat acatcagcgt
     3901 actggatatc ggtacgtcta aagtcctcgc actgatcggg gaagttcaag atgacgacaa
     3961 aatcaacatc gtcggtttgg ggcaggctcc ttcacggggc ttgcgcgcgg gcatggtaac
     4021 caatatcgat gccaccgtcc aagccatcag gcaggcggtc aatgatgccg agctgatggc
     4081 ggataccaaa attacccacg ttaccacagg tatcgcaggc aaccacatcc gcagtctcaa
     4141 ttcgcaaggt gtggttaaaa ttaaagacgg ggaagtcacg caggcagaca tcgaccgcgc
     4201 cattgaaacg gcaaaggcaa tcaatatccc gcccgatcaa aaaattctcg atgccgtggt
     4261 tcaagactac attatcgaca cccaacttgg cgtgagggag cccatcggta tgagcggtgt
     4321 gcgtctggat acgcgggtgc acatcattac cggtgcaagt acggcagtgc agaatgtcca
     4381 aaaatgtatc gagcggtgtg gtttgaaaag cgatcagatt atgcttcagc cgttggcaag
     4441 cgggcaggcg gtgctgactg aagatgaaaa agacctcggc gtatgcgtca tcgacattgg
     4501 tggcggaacg accgatattg ccgtttatat gaacggtgcc atccgccata cgtccgtcat
     4561 tccggccggt ggtaatctga ttaccaaaga tttgtccaaa tcgttgagaa cacctctcga
     4621 tgccgccgag tacattaaaa tccattatgg cgtggcatca tgcgatacgg aaggcttggg
     4681 tgagatgatt gaagttccgg gcgtgggtga ccggacatcg cgtcaggttt ccagtaaggt
     4741 tttggcagca atcatcagcg cacgtattca ggagattttt ggcgtagtgc tgggcgagct
     4801 gcaaaaatcg ggtttcccca aagaagtgct gaatgcgggt atcgttctga ccggcggtgt
     4861 gtccatgatg accgggattg tggaatttgc cgaaaaaatc ttcgatttgc ctgtacgcac
     4921 cggtgcgccc caagaaatgg gcggtttgtc cgaccgcgtc cgcacaccgc gcttttctac
     4981 cgccatcggg ctgcttcatg cagcatgcaa gctggaagga aacttgccgc agccggaaaa
     5041 cggtgcagtg caagagaggg aagtgggcgg cggtttgttg gcaagattga aacggtggat
     5101 tgaaaacagc ttctgaacag gtggattgcc gtttgacagg tgagaagtat tttgccagca
     5161 gcaagatact tcttatataa tgaataataa tttatttaaa ccgtcctctg aatggggcga
     5221 gcaggagttt ttgaatggaa tttgtttacg acgtggcaga atcggcagtc agccctgcgg
     5281 tgattaaagt aatcggcttg ggcggcggcg gttgcaatgc aatcaataac atggttgcca
     5341 acaatgtgcg cggtgtggag tttatcagtg ccaatacgga tgcgcagtct ctggcaaaaa
     5401 accatgcggc gaagagaatc cagttgggta cgaatctgac acgcggtttg ggcgcgggcg
     5461 cgaatcccga tatcggccgt gcggcagccc aggaagaccg ggaagccatt gaagaagcca
     5521 ttcgcggtgc gaatatgctg tttatcacga ccggtatggg tggcggtacc ggtaccggtt
     5581 ccgcgccggt tgttgctgag attgccaagt ctttgggcat tctgaccgtt gccgtggtta
     5641 cccgaccgtt cgcatatgaa ggtaagcgcg tccatgtcgc acaggcaggg ttggaacagt
     5701 tgaaagaaca cgtcgattcg ctgattatca tcccgaacga caaactgatg actgcattgg
     5761 gtgaagacgt aacgatgcgc gaagccttcc gtgccgccga caatgtattg cgcgatgcgg
     5821 tcgcaggcat ttccgaagtg gtaacttgcc cgagcgaaat catcaacctc gactttgccg
     5881 acgtgaaaac cgtgatgagc aaccgcggta tcgctatgat gggttcgggt tatgcccaag
     5941 gtatcgaccg tgcgcgtatg gcgaccgacc aggccatttc cagtccgctg ctggacgatg
     6001 taaccttgga cggagcgcgc ggtgtgctgg tcaatattac gactgctccg ggttgcttga
     6061 aaatgtccga gttgtccgaa gtcatgaaaa tcgtcaacca aagcgcgcat cccgatttgg
     6121 aatgtaaatt cggtgcggct gaagacgaga ccatgagcga agatgccatc cggattacca
     6181 ttatcgctac cggtctgaaa gaaaaaggcg cggtcggttt tgttccggca agggaggtag
     6241 aagcggttgc cccgtccaaa caggagcaaa gccacaatgt cgaaggtatg atccgcacca
     6301 atcgcggtat ccgcacgatg aaccttaccg ctgcggattt cgacaatcag tccgtacttg
     6361 acgactttga aatccctgcg attttgcgtc gtcaacacaa ttcagacaaa taatgtgctg
     6421 tttgcccgta aacctgctgc ctcccgaatc ggtttgtccg gtttgggagg tatgtttttc
     6481 aagatgttgc aatttcgtac ggtttgcggt cggcggattc agatttttcc acttgataca
     6541 gactttcaga tatggacact tcaaaacaaa cactgttgga cgggattttt aagctgaagg
     6601 caaacggtac gacggtgcgt accgagttga tggcgggttt gacaactttt ttgacgatgt
     6661 gctacatcgt tatcgtcaac cctctgattt tgggcgagac cggcatggat atgggggcgg
     6721 tattcgtcgc tacctgtatc gcgtctgcca tcggctgttt tgttatgggt tttgtcggca
     6781 actatccgat tgcactcgca ccggggatgg ggctgaatgc ctatttcacc tttgccgtcg
     6841 ttaagggtat gggcgtgcct tggcaggttg cgttgggtgc ggtgttcatc tccggtctga
     6901 ttttcatcct gttcagcttt tttaaagtca gggaaatgct ggtcaacgca ctgcctatgg
     6961 gtttgaaaat gtcgattgct gccggtatcg gtttgttttt ggcactgatt tccctgaaag
     7021 gcgcaggcat tatcgttgcc aatccggcaa ccttggtcgg tttgggcgat attcatcagc
     7081 cgtccgcgtt gttggcactg ttcggttttg ctatggtggt cgtattggga catttccgcg
     7141 ttcaaggcgc aatcatcatc accattttga cgattaccgt cattgccagc ctgatgggtt
     7201 tgaatgaatt tcacggcatc atcggcgaag taccgagcat tgcgccgact tttatgcaga
     7261 tggattttga aggcctgttt accgtcagca tggtcagtgt gattttcgtc ttcttcttgg
     7321 tcgatctgtt cgacagtacc ggaacgctgg tcggcatatc ccaccgtgcc gggctgctgg
     7381 tggacggtaa gctgccccgc ctgaaacgag cactgcttgc agactctacc gccattgtgg
     7441 caggtgcggc tttgggtact tcttccacca cgccttatgt ggaaagcgcg gcgggcgtat
     7501 cggcaggcgg acggaccggc ctgacggcgg ttaccgtcgg cgtattgatg ctcgcctgcc
     7561 tgatgttttc acctttggcg aaaagtgttc ccgcttttgc caccgcgccc gccctgcttt
     7621 atgtcggcac gcagatgctc cgcagtgcga gggatattga ttgggacgat atgacggaag
     7681 ccgcacccgc attcctgacc attgtcttca tgccgtttac ctattcgatt gcagacggca
     7741 tcgccttcgg cttcatcagc tatgccgtgg ttaaactttt atgccgccgc accaaagacg
     7801 ttccgcctat ggtatggatt gttgccgtat tgtgggcact gaaattctgg tatttgggct
     7861 gattgattcg atattaaaaa tgccgtctga aaggttttca gacggcattt tgtttgccga
     7921 tatatttaat ttttattaaa ttatataaaa atcaaataca taataaaata catcggattg
     7981 cttaaaaata atacattgtt tttatgtata aaatatttta taagttttca ggattttgat
     8041 tatcgaaaat ttttcttgat ttcctgacaa ttttattgaa acaaataatt caaaattaat
     8101 ctagtttaat catggaatta aaataaaata ttaaaattat gtaatgagtc tccttaaaaa
     8161 tgtttgacat tttcagtctt gtgttttaga ttatcgaaaa ataaaactac ataacactac
     8221 aaaggaacat tactatgaaa ccaattcaga tgttttcccc ttttctgaat aatccccttg
     8281 ttttcttctt gtctgcggtt ttgccgcata attccgaacg gtctgctgtt tttctttgat
     8341 tcgttttaaa tatcaataag ataatttttc ccatatattt ttaatgattg gattgggatg
     8401 cccgacgcgt cggatggctg tgttttgccg tccgaatgtg atggaagcct gtccatactg
     8461 aaaaaaagtc tataaaggag aaatatgatg agtcaacact ctgccggagc acgtttccgc
     8521 caagccgtga aagaatcgaa tccgcttgcc gtcgccggtt gcgtcaatgc ttattttgca
     8581 cgattggcca cccaaagcgg tttcaaagcc atctatctgt ccggcggcgg cgtggcagcc
     8641 tgttcttgcg gtatccctga tttgggcatt accacaatgg aagatgtgct gatcgacgca
     8701 cgacgcatta cggacaacgt ggatacgcct ctgctggtgg acatcgatgt gggttggggc
     8761 ggtgcattca atattgcccg taccattcgc aactttgaac gcgccggtgt tgcagcggtt
     8821 cacatcgaag atcaggtagc gcaaaaacgc tgcggccacc gtccgaacaa agccattgta
     8881 tctaaagatg aaatggtcga ccgtatcaaa gctgccgtag atgcgcgcgt tgatgagaac
     8941 ttcgtgatta tggcgcgtac cgatgcgctg gcggtagaag gtttggatgc cgctatcgaa
     9001 cgcgcccaag cttgtgtcga agccggtgcg gacatgattt tccctgaagc catgaccgat
     9061 ttgaacatgt accgccaatt tgcagatgcg gtgaaagtgc ccgtgttggc gaacattacc
     9121 gagtttggtt ccactccgct ttatacccaa agcgagctgg ctgaaaacgg cgtgtcgctg
     9181 gtgctgtatc cgctgtcatc gttccgtgca gcaagcaaag ccgctctgaa tgtttacgaa
     9241 gcgattatgc gcgatggcac tcaggcggcg gtggtggaca gtatgcaaac ccgtgccgag
     9301 ctgtacgagc atctgaacta tcatgccttc gagcaaaaac tggataaatt gtttcaaaaa
     9361 tgatttaccg ctttcagacg gccttccaat ctatccgcat cggccgtctg aaaattgaaa
     9421 atccataaaa aacaaaggag aaatacgatg actgaaacta ctcaaacccc gactttcaaa
     9481 cctaaaaaat ccgttgcgct ttccggcgtt gcggcgggta atacagcatt gtgtaccgtc
     9541 ggccgtaccg gcaacgattt gagctatcgc ggttacgaca tcttggattt ggcacaaaaa
     9601 tgcgagtttg aagaagtcgc ccacctgctg attcacggtc atttgcccaa caaattcgag
     9661 ctggccgctt ataaagccaa gctcaaatcc atgcgcggcc tgcctatccg tgtgattaaa
     9721 gttttggaaa gcctacctgc acatacccat ccgatggatg tgatgcgtac cggcgtatcc
     9781 atgctgggct gcgttcatcc tgaacgtgaa agccatccgg aaagcgaagc gcgcgacatc
     9841 gccgacaaac tgatcgccag cctcggcagc atcctcttgt actggtatca atattcgcac
     9901 aacggcaaac gcattgaggt tgaaagcgac gaagagacca tcggcggtca tttcctgcaa
     9961 ctgttgcacg gcaaacgccc aagcgaatcc cacatcaaag ccatgcacgt ttcactgatt
    10021 ctgtatgccg aacacgagtt caacgcttct accttcaccg cccgcgtgat tgccggtaca
    10081 ggctctgata tgtactccag cattaccgga gcaatcggcg cgttgaaagg tccgaaacac
    10141 ggcggcgcga acgaagtggc ttacgatatt caaaaacgct accgcaatgc cgacgaagcc
    10201 gaagccgaca tccgcgaacg catcggccgc aaagaaatcg tgatcggttt cggtcatccg
    10261 gtgtacacca tctccgaccc tcgcaacgtt gtcattaaag aagtggcacg cggtttgagc
    10321 aaagaaaccg gcgatatgcg cctctttgac attgccgaac gtttggaaag cgtgatgtgg
    10381 gaagagaaaa aaatgttccc gaatctggac tggttctctg ccgtttccta ccaaaaattg
    10441 ggcgtaccga ccgctatgtt cacaccgctg ttcgtaattt cccgtacaac cggttggagc
    10501 gcacacgttc ttgagcaacg caaagacggc aaaatcatcc gtccgagcgc aaactacacg
    10561 ggccctgaag atttggcgtt tgtggagatt gaagaacgct gatgattttc agacgacctt
    10621 gtttgtacaa ggtcgtctga aaaaagaaat ttaatgaatt tattggcaca ctaattatta
    10681 atgcggaaca tttgatggat aaggacaagg ggtcttatgc gggtattcct gtacaaaata
    10741 ccaaagagtt agtttggcag aaaatacaag acatacctat ttctgaatgt ggggaaccgt
    10801 tggtcagtgt tggtaatacc ggacgcattc gtgtcaatcc tgtttatttt tctcagggta
    10861 ttgaaggggc gataaatagt gttttattgc gtagaagtgt tgctgatagg ctgactcagg
    10921 ttgtctcttt gctgccggaa gtgtacgggt tggaaatttt tgatggttgg cgtcctgtca
    10981 tagtgcaaag agcattacga gaaaatatga agcaagaaat tgaaaaacgc catccggaat
    11041 atgatgaagt tcaagttaga gaagcactgg actgttttgc tgctgatcca gatcgggcag
    11101 gaatgcctct gccccatttg acaggcggat ctgttgatgt cggattgttt gatataaaaa
    11161 gtggcaaaag tttggatatg ggaagtgagt ttgatgcaac tggacattta tcttatagcg
    11221 atgctttaga gaaagaaggt gagtatttct cctctgctcg taatttacgc cggattttga
    11281 ttcatgcgat gaaagaggca ggatttagta atttgccaac cgaatggtgg catttcgatt
    11341 atggcaacca aaattgggct tattttaccc aacaaagcaa cgcagttttt ggggcggtag
    11401 aagagcagga tacttaaatt aaaataaaaa ttgggaggaa aaatgcaaac tttaatttca
    11461 gcagataatc atttgctgct gtgggctttt gttatgttag ctgccgctgc tgcgattttt
    11521 attgagcaaa acagtcgctt ggctgggaaa gtccctggtg cagtattagc tttattgatt
    11581 gcgttgattg cttctaattt gggtgttatt ccgacggatg ctccagtatt tgatgctgta
    11641 tggtcttata ttgtacctct tgctattccg ttgttattgt ttcaattaga tcttcatgct
    11701 ctatttaagg aaagtggacg tatgctgttt attttcctga ttagttcact agggacggtc
    11761 attggaacgc ttgtctcatt tgcactattg aaaaactata ttcctgaact agataaggta
    11821 gctggcatga tttcagcatc ttatacggga ggtggtgtta attttgcagc tatgtcagct
    11881 aagcttaacc ctgctaaaga tgttattgca gcaacaattg ttgctgataa tttgatgatg
    11941 gcttgttact tttttatttt gattggtatc tcttcctcat attgggtcag aaaagtttgg
    12001 ggaagtccat atcaggataa attggagcag gaatatcatg atccgagtgt gaataaggct
    12061 gccgagtatt ggaaacctaa atccatttcg ctacagagta tagccttatc tttggctgcc
    12121 tcgattttgt tggtcgcagt ttcattctca ttatccagtt ttttgcaaaa tcattttcaa
    12181 agtgttgatg gtgttgcatt aaaaatgctg acaggtttaa ttagtgacaa atatttgctg
    12241 ttaacgacat ttacattggc agttgtttta tttttccgta aaggcattca aaaactagat
    12301 ggcagtcaag aattagggac atattgtatt tatctgtttt ttgttgtgat tggtgttcct
    12361 gcctctatac cgttaattat taaaacagca ccattactct ttgtttttac tttgattatt
    12421 gcggtattga atttgttact gacgttagtg ttaggcaagc tgttcaaatt cagtattgaa
    12481 gaaattgtat tggcttgtaa tgccaatatt ggagggccga ctactgcagc agccttagcc
    12541 atcagtaaag gttggcgtga tttagtcggt gcaattttgt taattggtac tgtaggctac
    12601 attatcggta actatatagg ttcgtttgta tatgccctat tgagctgaag actaatctaa
    12661 caatccatga accttttcag acgaccccct tccaaaaacg tcggctgaaa cctcaaacca
    12721 caagaaaaac agatccccag gagaaccgac atggctgcca accaacgtta ccgcaaaccg
    12781 ctgcccggta cggatttgga atactacgac gcgcgtgcgg cgtgtgagga catcaagccc
    12841 ggctcttacg acaagctgcc ttatacaagc cgtatcttgg ctgagaactt ggtcaaccgc
    12901 gcggacaaag tcgatttgcc gacgctgcaa agctggctgg gccagttgat agaagggaag
    12961 caggaaatcg actttccgtg gtatcccgcg cgggtggtgt gccacgatat tctggggcag
    13021 accgcgctgg tggatttggc gggcttgcgc gatgcgattg ccgaaaaagg cggcgatcct
    13081 gccaaagtga atccggtggt gcaaacccag cttatcgtcg accactctct ggcggtggag
    13141 tgcggcggtt acgatcctga tgccttccgc aaaaaccgcg aaatcgaaga tcgacgcaac
    13201 gaagaccgtt tccacttcat caactggaca aaaaccgcgt ttgaaaatgt ggacgtgatt
    13261 ccggcgggca acggcatcat gcaccaaatc aatctagaaa aaatgtcgcc ggttgttcaa
    13321 gttaaaaacg gcgtggcttt ccccgatacc tgcgtcggca cggattcgca cacgccgcac
    13381 gtcgatgcgc tgggcgtgat ttccgtgggc gtgggcggat tggaagcgga aaccgtaatg
    13441 ctgggacgcg cgtccatgat gcgcctgccc gatattgtcg gcgttgagct gaacggcaaa
    13501 cggaaggcgg gcattacggc gacggatatt gtgttggcac tgaccgagtt tctgcgcaaa
    13561 gaacgcgtgg tcggggcgtt tgtcgaattc ttcggcgagg gcgcgagaag cctgtctatc
    13621 ggcgaccgcg cgaccatttc caacatgacg ccggagttcg gcgcgactgc cgcgatgttc
    13681 gctattgatg agcaaaccat tgattatttg aaactgaccg gacgcgacga cgcgcaggtg
    13741 aaattggtgg aaacctacgc caaaaccgca ggcttgtggg cagatgcctt gaaaaccgcc
    13801 gtttatcctc gcgttttgaa atttgatttg agcagcgtaa cgcgcaatat ggcaggtcca
    13861 agtaacccgc atgcccgttt tgccaccgtc gatttggcgg cgaaagggct ggcgaagcct
    13921 tacgaagagc cttcagacgg acaaatgccc gacggcgcgg tcatcatcgc cgcgattacc
    13981 agttgcacca acacttccaa cccgcgcaac gtcgttgccg ccgcgctctt ggcgcgcaac
    14041 gccaaccgct tcgggctgaa acgcaaaccg tgggtcaaaa cctcgtttgc ccccggttcg
    14101 aaagtggcgg aaatttattt gaaagaagca ggcctgctgc ccgaaatgga aaaactcggc
    14161 ttcggtatcg tcgccttcgc ctgcaccacc tgcaacggca tgagtggcgc gctggatccg
    14221 aaaatccaga aagaaatcat cgaccgcgat ttgtacgcca ccgccgtatt atcaggcaac
    14281 cgcaacttcg acggccgtgt ccatccgtat gcgaaacagg ctttcctcgc ttcgcctccg
    14341 ttggtcgttg cctacgcgct ggcaggcagt atccgtttcg atattgaaaa cgacgtactc
    14401 ggcgttgcag acggcaagga aatccgcctg aaagacattt ggcctgccga tgaagaaatc
    14461 gatgccgtcg ttgccgaata tgtgaaaccg cagcagttcc gcgatgtgta tgtaccgatg
    14521 ttcgacaccg gcacagcgca aaaagcacct agtccgctgt acgattggcg tccaatgtcc
    14581 acctatatcc gccgcccacc ttactgggaa ggcgcattgg caggggagcg cacattgagc
    14641 ggtatgcgtc cgctggcgat tttgcccgac aacatcacca ccgaccacct ctcgccatcc
    14701 aatgcgattt tggcaagcag tgccgcaggc gaatatttgg cgaaaatggg tttgcctgaa
    14761 gaagacttca actcttacgc aacccaccgc ggcgaccact tgaccgccca acgcgcaacc
    14821 tttgccaatc cgaaactgtt taacgaaatg gtgagaaacg aagatggcag tgtacgccaa
    14881 ggttcgctgg cacgcgttga acccgaaggc caaaccatgc gcatgtggga agccatcgaa
    14941 acctatatga accgcaaaca gccgctcatc atcattgccg gtgcggacta cggtcaaggc
    15001 tcaagccgcg actgggctgc aaaaggcgta cgcctcgccg gtgtggaagc gattgttgcc
    15061 gaaggcttcg agcgtatcca ccgtaccaac ttgatcggta tgggcgtatt gccgctgcag
    15121 ttcaaaccgg gtaccaaccg ccacaccttg caactggacg gtacggaaac ctacgacgtg
    15181 gtcggtgaac gcaaaccgcg ctgcgatctg accctcgtga ttcaccgtaa aaacggcgaa
    15241 accgtcgaag ttcccgttac ctgccgcctc gatactgcag aagaagtatt ggtatatgaa
    15301 gccggcggcg tgttgcaacg gtttgcacag gattttttgg aagggaacgc ggcttagagg
    15361 tcgtctgaaa agcaagacgt agcgtgggtc gggttcaaca ttttgctcat tcacgtaatt
    15421 ctcgatatgg caggcatcta ctgtaaatcg tcattcccgc gcaggcggga atccagaaag
    15481 tggaattgag gaaacctt
//
LOCUS       DAXIDM010000045        14377 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000045 DAXIDM010000000
VERSION     DAXIDM010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 14377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14377
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.045"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            113..3211
                     /locus_tag="ACFOAE_001143"
     CDS             113..3211
                     /locus_tag="ACFOAE_001143"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HFC6884642.1"
                     /translation="MNLETKPIAETPNFIVLDQYEKIEQSGSYQSENRLEAELIADLQ
                     NQGYEYRKDLNSQSRLLENLRAQLQRLNDVAFSDGEWARFLTEYLDRPSENITDKTRK
                     IHDDHIYDFAFDDGRLKNIYLLDKKNLARNHVQLINQFEQTGTHANRYDVTVLVNGLP
                     LVQIELKKRGVAVREAFNQVHRYSKESFNSENSLFKFLQIFVISNGTDTRYFANTTKR
                     DKNSFDFTMNWARSDNHPIKDLKDFTATFLQKSVLLGVLLHYSVFDANNTLLIMRPYQ
                     IAAAERILWKINSSALAKNWSKPESGGYVWHTTGSGKTLTSFKAARLATESAFIDKVF
                     FVVDRKDLDYQTMKEYQRFSPDSVNGSESTTGLKRNLEKDDNKIIVTTIQKLNNLMKS
                     EDNLPVYHQRVVFIFDECHRSQFGEAQKNLKKKFKKFCQFGFTGTPIFPENALGAETT
                     AGVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKAVEAEQDEKKLSAAENRQALL
                     HPERIREITQYILNQFRQKTHRLNAGGKGFNAMFAVSSVDAAKCYYEAFKTQQAGSLH
                     PLKVATIFSFAANEEQNAVGEIVDETFEPEAMDSSAKEFLQAAINDYNACFKTNFGTD
                     SKAFQNYYRDLAKRVKNQEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLMQAFSR
                     TNRIYDATKTFGNIVCFRDLEQATIDAITLFGDKNTKNVVLEKSYEEYMNGYTDSQTG
                     EARRGYLDVAKELRQRFPDPDKIETEKDKKDFAKLFGEYLRAENVLQNYDEFAALREL
                     QSVDAADEDAMKAFQEKYYLSDEDVQEMRQVPMPSERAVQDYRSAYNDIRDWLRRQKA
                     GEQKEQSKIDWDDVVFEVDLLKSQEINLDYILQLVFEHHKKIKGKAELVEEIRRIIRA
                     SIGHRAKEGLIVDFINDTDLDKVPDVPAILETFYTYGQEVMRHEAAGLIVAEGLNETA
                     AKRYLTGSLKRGYASENGTELTETLPKMSPINPQYLTKKQSVFQKIAAFVEKFAGIGT
                     DI"
     gene            complement(3259..5538)
                     /gene="clpA"
                     /locus_tag="ACFOAE_001144"
     CDS             complement(3259..5538)
                     /gene="clpA"
                     /locus_tag="ACFOAE_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003746132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0043335 - protein unfolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HFC6884643.1"
                     /translation="MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNV
                     LKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVETRPTLGFQRVMQRAMVHTQSAGK
                     AAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDDEDGNDSDGLGREG
                     EEAEQKTGSLSDYTVNLNTEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAG
                     VGKTALAEGLAHQIVNGGIPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLE
                     KIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGSLRCIGATTYDEYRTIFDK
                     DHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINE
                     RFLPDKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVSRIPEKTVSHDDKQVL
                     QFLGRDLKNMVYGQENAIDALVAAVKMSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQ
                     LAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNKQPHCVLLLDE
                     IEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKR
                     ERGDEMQAINKLFTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAE
                     FTSALHKYLAEKGFDPQMGARPMHRLIQEKIRKPLADELLFGKLADGGFVRIDWDAAK
                     EEAVLKFKKNKVKPEAEPV"
     gene            complement(5540..5842)
                     /gene="clpS"
                     /locus_tag="ACFOAE_001145"
     CDS             complement(5540..5842)
                     /gene="clpS"
                     /locus_tag="ACFOAE_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HFC6884644.1"
                     /translation="MTAQHQSDTLLHRLNTLPPKRYGVFLLNDDYTTMEFVVEILTEI
                     FMLGQEQAVAVMLLVHHEGKGLCGTYTRDIAQTKQQQVMQRAKAEGHPLQCIVEEI"
     gene            6085..6288
                     /locus_tag="ACFOAE_001146"
     CDS             6085..6288
                     /locus_tag="ACFOAE_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFC6884645.1"
                     /translation="MATGIVKWFNDAKGFGFITPDEGGEDLFAHFSAINMEGFKTLKE
                     GQRVSFDVTTGPKGKQAANIQAA"
     gene            complement(6585..7916)
                     /gene="pmbA"
                     /locus_tag="ACFOAE_001147"
     CDS             complement(6585..7916)
                     /gene="pmbA"
                     /locus_tag="ACFOAE_001147"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HFC6884646.1"
                     /translation="MLFNHTASELLDLCRRTLDLAKATGATAAEADFSESLGQSVSVR
                     LGEIEQIEFQQDKSLDITVYVGKRKGRAGTADFSEQALRDTVRAAADIARHTAEDGCA
                     GLADACLMAKHIGDPDLYHEWDLDTEAAVELAKQCEQAALNEDERIENSEGAAVQTGH
                     YQYVYGNTHGFAAHRQGTHHSISCSVVAADENGMQRDYWYDSACRHPDMDSPETIGQT
                     AARRTLRRLGSRSIPTGSYPVLFDTTVSGGLIGHLVGALSGGALYRQSSFLIDSIGKK
                     VLPDFLNLREEPHIPRSFRSSYFDAEGVATAPRFVIQNGIVEGYFLSSYSARKLGMQT
                     TGNAGGAHNLYLNHTHETQSDLLKEMGTGLLVTELMGQGANTITGDYSRGAAGFWVEN
                     GVIAYPVHEITVAGRLQDMYRDIVGVADDALRRSSNKIGSILIAGMTVAGS"
     gene            8070..8576
                     /gene="yjgA"
                     /locus_tag="ACFOAE_001148"
     CDS             8070..8576
                     /gene="yjgA"
                     /locus_tag="ACFOAE_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis factor YjgA"
                     /protein_id="HFC6884647.1"
                     /translation="MFEQEDEWISKTQMKKQMNGLQDLGMELTKLSNDTLKKIGLDED
                     LYEAVVTYKKITSNGALKRQAQFIGRLMRDTDPAPIEAFLAKLRGDDAAHNAFLQRVE
                     QARVRLLADDGALTQFMSDFPHADAGKLRTLIRNTKKEQEQNKPPKNFRALFQELKTV
                     MENGDAEI"
     gene            8623..9339
                     /locus_tag="ACFOAE_001149"
     CDS             8623..9339
                     /locus_tag="ACFOAE_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884648.1"
                     /translation="MLFRKTTAAVLAATLMLNGCTAMMWGMNDPFSQTTAYKHVDKDQ
                     IRAFGVVAKDNAQLEKGSLVMMGGKYWFVVNPEDSAKLTGILKIGLDKPFQIVEDTPS
                     YARYQALPVKLESPASQNFSTEGLCLRYDTDRPADIAKLKQLEFEAVELDNRTIYTRC
                     VSAKGKYYATPQKLNADYHFEQSVPADIYYTVTKKHTDKSKLFENIAYTPTTLILDAV
                     GAVLALPVAALIAATNSSDK"
     gene            9408..11108
                     /gene="recJ"
                     /locus_tag="ACFOAE_001150"
     CDS             9408..11108
                     /gene="recJ"
                     /locus_tag="ACFOAE_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFC6884649.1"
                     /translation="MSVKIQTRSVNTNVFNHLLTAGADPLIARLCASRGVQSPAELDD
                     KLAALLPYQTLTNCEAAAGRLADAVERQEKILIVADYDADGATACSVGMSGLAAMGAK
                     VDFLVPNRFEHGYGLTPELAEIAAEQGVDLLITVDNGIASIAGVARAQELGLDVIVTD
                     HHLPAETVPDCIIVNPNQKGCGFQSKSLAGVGVIFYVLMALRAELRRRDYFSDGIKEP
                     NLGDLLDLVALGTVADVVTLDHNNRILVSQGLKRMRSGKMRPGIRALFEVARRDWRKA
                     QPFDMGFALGPRINAAGRLDDMSVGIACLLARDDTEAQELAAQLNNLNIERREIEQSM
                     LQDALNAFPETLPSGQMTLVAYRDDFHQGVVGIVASRLKDRFYRPTIVFAPADNGEVR
                     GSGRSIPNLHLRDALDLVSKRHPDLILKFGGHAMAAGLSILEHNIPAFQTAFEEAVRE
                     MVCEDDLSQTFITDGSLPARDITLEQAQNLAKHVWGQGFAPPSFTDEFHVVRQQPLGA
                     EGKHKKAWLQKDGCEFEAMFWRCSEDIPEYIRTVYRPVANEWRNNLELQLYIDYWEAA
                     "
     gene            11405..12766
                     /locus_tag="ACFOAE_001151"
     CDS             11405..12766
                     /locus_tag="ACFOAE_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HFC6884650.1"
                     /translation="MLKKWLNKMLPSGRSSKKAESKTVIPAERHNIRAEMLSFAAENV
                     IRRLKGAGFQAYVVGGAVRDLLLGIEPKDFDVATDATPEQVHKLFRRSRIIGRRFQIV
                     HVMNGAEIIEVTTFRGGAKVHQNAHGRIMKDNTYGSIEEDAMRRDFTCNALYYDPEKE
                     EILDFHNGIADVAAHRLVMIGDAAERYQEDPVRILRAIRLSGKLGFDLSEETAAPIAE
                     SICRLKHEPVARLFDEIMKLLFSGHARECLKRLNGFDIPDDIHPLLNALRVSDGIAGK
                     MTVLALKNTDERLRADKSVSVGFVLAALMWPELERHWKSNLQQGLKPVPALSDAINTM
                     RETVERGWGVPQRFSATMREIWMFQPQFENRKGARPHKLFAQARFRAAYDFLLLRAET
                     GNADRALAEWWTAFQTASTEQRSEMTKNEAAARHEKNEGQAKKRRRRRRKPKPKVVGT
                     DWE"
     gene            12939..13262
                     /locus_tag="ACFOAE_001152"
     CDS             12939..13262
                     /locus_tag="ACFOAE_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884651.1"
                     /translation="MKKCILGILTACAAMPAFADRIGDLEARLAQLEHRVAVLESGSN
                     TVKIDLFGSNSTMYVCSVTPFQKTFEASDRNEGVARQKVRQACNRETSAMFCEDEAIR
                     CRKFD"
     gene            complement(13373..14326)
                     /locus_tag="ACFOAE_001153"
     CDS             complement(13373..14326)
                     /locus_tag="ACFOAE_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFC6884652.1"
                     /translation="MTHTVHLHLEETDNLALQRLCGSFDNNLDLLAKALDIHISRRFE
                     HFTFNGAFAHAGKRALLKLLETAQTRDLNDGDIRLAAVEAQTEDAGHQEKNHDHAYYF
                     RTKRGSIGGRTPRQNGYIRALLNHDIVFGLGPAGTGKTYLAVAAAVDAMEKHQVERII
                     LVRPAVEAGEKLGFLPGDLTQKVDPYLRPLYDALYDLMGFDRVTKLIEKGLIEIAPLA
                     YMRGRTLNGAYIILDEAQNTTPEQMKMFLTRIGFGAKAVITGDTSQIDLPKNIKSGLK
                     DAREKLHGVEGLYFHTFTGEDVVRHPLVQKIVEAYESAEHD"
BASE COUNT         3368 a         3611 c         4093 g         3305 t
ORIGIN      
        1 ggacacaacc accccgcatt ccgccgaagc cgaccaaagc agcctgcaca ttttcaggca
       61 gcccaatccg aacatcaaac tgtttaaaac ccgaccctgc aaaggacgaa ctatgaacct
      121 cgaaaccaaa cccatcgccg aaacgccgaa tttcatcgtg ctcgaccaat atgaaaaaat
      181 cgaacagtcg ggcagctacc aatcggaaaa ccggttggaa gcggagttaa tcgccgattt
      241 gcagaatcag ggttacgaat accgcaagga tttgaacagc caaagcaggc tgctggaaaa
      301 cctgcgcgcg cagttgcagc ggctgaacga tgtggcgttt tcagacggcg aatgggcgcg
      361 gtttttgacg gaatatctgg acaggccgtc tgaaaacatt accgataaaa cccgcaaaat
      421 ccacgacgac catatttacg atttcgcttt tgatgacggc cgtctgaaaa acatttatct
      481 gctggacaaa aaaaaccttg cccgcaacca tgtgcagctt atcaaccagt ttgagcagac
      541 gggcacgcat gcaaaccgct atgacgttac cgtgttggta aacggcctgc cgctggtgca
      601 gattgaattg aaaaaacgcg gtgtggcggt gcgcgaggca ttcaatcagg tgcaccgtta
      661 cagcaaagag agcttcaaca gcgaaaattc gttgttcaaa ttcctgcaaa tcttcgtgat
      721 ttccaacggc acggacacgc gctatttcgc caacaccacc aagcgcgaca aaaatagctt
      781 cgatttcacg atgaattggg cgcggtcgga caatcatccg attaaggatt tgaaagactt
      841 tactgccacg ttcctgcaga aaagcgtatt gctgggcgtt ttgctgcatt acagcgtgtt
      901 cgatgcgaat aatacgctgc tgattatgcg gccgtaccag attgccgccg ccgaacgtat
      961 tttgtggaaa atcaacagtt cggctctggc aaagaattgg agtaagcccg aaagcggcgg
     1021 ctatgtttgg cataccacgg gcagcggcaa aacgctgacc agctttaagg cggcgcgtct
     1081 ggcgacagaa tcggcgttta tcgacaaggt tttcttcgtg gtggacagga aggatttgga
     1141 ctatcagacg atgaaggaat accagcgttt ttctcccgac agcgtaaacg gttcggaaag
     1201 cacgacgggc ttgaaacgca atttggaaaa agacgacaac aaaatcatcg ttaccaccat
     1261 ccaaaagctg aacaacctga tgaagagtga agataatctg ccggtttacc atcagcgggt
     1321 tgtctttatt ttcgacgaat gccaccgctc gcaattcggc gaagcgcaaa aaaacctgaa
     1381 aaagaaattt aaaaaattct gccagttcgg ctttaccggc acgccgattt ttcccgaaaa
     1441 cgctttgggc gcggaaacca cggcgggcgt gttcgggcgg gagctgcatt cttatgtgat
     1501 taccgatgcc atccgcgatg aaaaagtatt gaaattcaaa gtggattaca acgatgtgcg
     1561 cccgcagttc aaagccgtgg aagcggaaca ggacgagaag aaactgagtg ccgccgaaaa
     1621 tcgccaagcc ctgctgcacc ccgaacgcat ccgcgaaatc acgcaatata tcctgaacca
     1681 gttcaggcag aaaacgcacc ggctgaacgc aggcggcaaa ggcttcaacg ccatgtttgc
     1741 cgtcagcagc gtggatgcgg cgaagtgcta ttatgaagcg ttcaaaacac aacaggcagg
     1801 cagcctgcac ccgctgaaag tggccaccat tttttccttt gcggccaacg aagagcagaa
     1861 cgccgtcggt gaaattgttg acgagacctt tgaaccggaa gcgatggaca gcagcgcgaa
     1921 agaatttttg caggctgcca tcaacgatta caacgcctgt ttcaaaacca atttcggcac
     1981 ggacagcaaa gcctttcaga actactaccg cgatttggca aaacgggtga aaaaccagga
     2041 agtggatttg ctgattgtgg tcggcatgtt tttgacgggt tttgacgcgc cgacgctgaa
     2101 tacgctgttc gtcgataaaa acctgcgcta tcacggcctg atgcaggcgt tttctcgcac
     2161 caaccgcatt tatgatgcta ccaaaacctt cggcaatatt gtctgcttcc gcgatttgga
     2221 gcaggcaacc attgatgcga tcacgctctt cggcgataaa aacaccaaaa atgtagtgct
     2281 ggaaaaaagc tacgaagaat atatgaacgg ctataccgac agccagaccg gcgaagcgcg
     2341 gcgcggttat ctggatgtgg caaaagaatt gcgccaacgt ttccccgatc ccgacaaaat
     2401 cgaaacggaa aaagacaaaa aagattttgc caaactcttc ggcgaatacc tgcgggcgga
     2461 aaacgtattg cagaactacg atgaatttgc cgcgctgcgt gaattgcaga gtgtggatgc
     2521 ggcggacgaa gatgcgatga aggcgtttca ggaaaaatac tacctgagcg atgaagacgt
     2581 gcaggaaatg cggcaagtgc cgatgccgtc tgaaagggcg gtgcaggact accgttccgc
     2641 ctacaacgac atccgcgact ggctgcgccg ccaaaaagca ggcgaacaga aagagcaatc
     2701 gaaaatcgat tgggacgatg tggtttttga ggtggatttg ctcaaatcac aggaaatcaa
     2761 tctggattac atcctgcaac tggttttcga acaccacaaa aaaatcaaag gcaaagcgga
     2821 gctggtggaa gaaatccgcc gcatcatccg cgccagcatc ggccaccgcg ccaaagaggg
     2881 tctgattgtg gatttcatca acgatacgga tttggacaaa gtacccgacg ttcccgccat
     2941 actggaaacc ttttacacct acgggcaaga ggtgatgcgg cacgaagcgg caggattgat
     3001 tgtcgccgaa ggcctgaacg aaaccgccgc caaacgctat ttgaccggct cgctcaaacg
     3061 cggctatgcc agcgaaaacg gcacggaact gaccgaaacc ctgccgaaaa tgagtccgat
     3121 caacccgcaa tatctgacga agaaacaaag tgtttttcaa aagattgcgg cgtttgtgga
     3181 gaagtttgcc ggaataggga ccgatatttg acaaaatgcc gtctgaacct ttcagacggc
     3241 tttttatttt tcaactggtt aaacaggttc tgcttcaggt ttgactttgt ttttcttgaa
     3301 tttcaacacg gcttcttctt ttgcagcatc ccagtctatc cgcacaaagc cgccgtcggc
     3361 gagtttgccg aacagcagtt cgtcggcgag cggtttgcgg attttttcct gaatcaggcg
     3421 gtgcatcggg cgcgcaccca tttgcgggtc gaaacctttt tccgccagat atttgtgcaa
     3481 tgccgacgtg aattcggctt cgactttttt gtcgaggagc tggtgttcga gctggagcag
     3541 gaatttgtcc acgactttga cgatgatggg ttcggacaag ggtgcaaacg ggataatcgc
     3601 gtccaagcgg ttgcggaact cgggcgtgaa gagcttgttg attgcctgca tttcgtcgcc
     3661 gcgttcgcgc ttggcggtaa agccgaggct ggggcggctg aggctttccg cgcctgcgtt
     3721 ggtggtcata atcaggatga cgttgcggaa atcggcactc ttgccgttgt tgtcggtcag
     3781 tttgcctgcg tccatgactt gcaggaggac gttgaaaatg tcggggtggg ctttttcgat
     3841 ttcgtccaag agcaatacgc aatgcggctg tttgttgacg gcttcggtca aaaggccgcc
     3901 ttgttcaaag ccgacgtagc ccggtggcgc gccgatgagg cgcgatacgg catggcgttc
     3961 catgtattcg gacatatcaa agcgttgcag cggtacgccc agcgagtagg caagctgttt
     4021 ggcggcttcg gttttgccca cgccggtcgg gccggagaag aggaagctgc ctatcggttt
     4081 gtcgggcagg gcaaggccgg aacgcgacat tttgacggcg gcaaccagcg cgtcgatggc
     4141 gttttcttga ccgtaaacca tgtttttcaa atcgcgaccg aggaattgca gcacttgttt
     4201 gtcgtcgtgc gacacggttt tttcgggaat ccgcgaaact ttggcgatga cggtttcgat
     4261 ttgtgctttg ccgatgactt ttttctgttt ggatttgggc agaatccgtt gcgccgcgcc
     4321 tgcttcatcc attacgtcga tggctttgtc gggcaggaaa cgctcgttga tgtagcgtgc
     4381 ggagagttcg gcggcggctt cgagtgcgcc ttgagtgtag cggacttggt ggaaggcttc
     4441 aaacatcggt ttcaagccgc gcaggatttg aacggtttcg gaaacggtgg gttcgaccac
     4501 gtcgattttt tggaagcggc ggcttaaggc atggtctttg tcgaaaatgg tgcggtattc
     4561 gtcgtaggtg gtcgcgccga tgcagcgcag cgaacctttt gccagcgcgg gtttgagcag
     4621 gttggacgcg tccatggtgc cgccgctggt gctgcccgcg ccgatgatgg tgtggatttc
     4681 gtcgataaac aaaatggcgt gcgggatttt ttcgagctgt ttcaagacgg atttgacccg
     4741 cgcttcaaag tcgccgcggt atttcgtgcc cgccaacagc gagcccatat ccagcgcgta
     4801 cacttcggca tctttaagcg cgtctggaat gccgccgttg acgatttgat gtgccaaacc
     4861 ttccgccagc gcggttttgc ccacgcccgc ttcgccgacc aaaagcggat tgtttttgcg
     4921 gcggcggcat aggatttgca ccagccgttc catttcgtgt ttgcgaccaa tcaaagggtc
     4981 gatacggccg gctttgactt cggtgttgag gttgacggtg tagtcggaaa gggagccggt
     5041 tttttgttcc gcttcttcgc cctcgcgtcc caggccgtct gaatcattgc catcctcgtc
     5101 atcgggcgag ccatgggcaa tacagcgcaa aacttcaaaa cgcgtaaccg attgcagctt
     5161 gaggaaatag acggtgtggc tgtcggtttc gctcatcagc gcgaccaaaa cgtccaacgg
     5221 ttcgactgcg gcttttccgg cagactgggt atgcaccatc gcccgttgca tcacgcgttg
     5281 gaagccgagc gtgggccggg tttcgaccgt gtctaaaagg tgttcgggaa tcaggggggt
     5341 gttttcggca acgctggcgg cgagctgttc ggacaccact ttcaaatccg cgccgcatag
     5401 ttttaagacg ttcggcacgg aggcatcttc ttcgatgagt accaaaagca gatgctcgag
     5461 gctgataaat tcataatgag ccttacgcgc ctcgcggtaa agctgctgca aaatctgttc
     5521 caattcgggt gcaagcatat taaatctcct cgacaataca ttgcagcgga tgcccttcgg
     5581 cttttgcccg ctgcatgact tgttgttgtt tggtttgggc aatatcgcgc gtgtaagtgc
     5641 cgcacaggcc tttgccttcg tgatgaacca agagcatcac cgctaccgcc tgttcttgtc
     5701 cgagcataaa gatttcggtc aggatttcga cgacaaattc catcgtggtg taatcgtcgt
     5761 tcaataggaa aacgccgtaa cgtttcggcg gcagggtgtt cagacggtgc aagagcgtgt
     5821 cggattggtg ttgcgcggtc atagtgtgtc ccatttgaaa gccgcgttca gacggcattt
     5881 ttgttgtatt ttcggtactt ttgcctattt tcccactttt ttgaaaacat agcttgacgt
     5941 tttgtcttaa caaatgtaaa aagacggtta agcaggattg ggcatccgcc gagtatatca
     6001 agctggaagg aacgccagac ggctcggttt gccgtatgcc ttgttttgct gattttgtta
     6061 atttttgagt ataggaagtt tctaatggca accggtatcg taaaatggtt taacgacgct
     6121 aaaggttttg gtttcatcac tcctgatgaa ggcggcgaag atttgttcgc tcacttctca
     6181 gcaatcaata tggaaggttt caaaaccctg aaagaaggcc aacgcgtctc tttcgacgta
     6241 accaccggcc ctaaaggcaa acaggccgcc aacattcagg ctgcttaatt cctgatgtac
     6301 ggtcaaatgt atatttgaaa acggcgggac aggcaatgtc ccgccgtttt tgtctgccgt
     6361 tttgccggcg gcggaaaaac cccaatcccc gcacgcctta tcctgagctt gtgtgtaccc
     6421 tgttgtggac aagtggctta gtattttgac ggataaggga aaatcagtgc tgatgaaaaa
     6481 atgtgcaatg ttgtcggcaa aaggcggtgc ggcataaaac ggcaaacggg caggcacggg
     6541 gcaaaacgtg ctgccttcgt cttcagacgg catcggcagg gcgttcagct tccggcaacc
     6601 gtcatccccg caatcagaat cgagccgatt ttgttggacg aacgccgcaa agcgtcatcc
     6661 gccacgccga caatgtcgcg gtacatatcc tgcaagcgtc cggctacggt aatctcgtgg
     6721 acggggtagg caatcacgcc gttttccacc caaaaacccg ccgcgccgcg cgagtagtca
     6781 ccggtaatgg tgttcgcgcc ctgtcccatc agttcggtaa ccaataatcc cgtccccatt
     6841 tctttcagca ggtcggattg cgtttcgtgc gtatggttca aatacaggtt gtgcgcgccg
     6901 ccggcgttgc ccgtggtctg cataccgagt ttgcgcgcgc tgtaactgct gaggaaatag
     6961 ccttcgacaa tgccgttttg aatcacgaag cgcggtgcgg tggcaacgcc ttccgcatca
     7021 aaatagctgc tgcggaaaga gcgggggatg tgcggttctt cgcgcaggtt gaggaaatcg
     7081 ggcaggactt ttttgccgat gctgtcgatc aggaaactgc tttggcggta gagcgcgccg
     7141 ccggagagtg cgccgacgag gtgtccgata agaccgcccg aaacggtggt atcgaagagg
     7201 acggggtagc tgcctgtcgg gatgctgcgg ctgccgagtc ggcgcaaagt gcggcgggcg
     7261 gcggtttgac cgatggtttc ggggctgtcc atatccggat ggcggcaggc ggaatcgtac
     7321 cagtagtcgc gctgcatccc gttttcgtcg gcggcaacga cgctgcagga aatgctgtgg
     7381 tgcgtgcctt gccggtgtgc ggcaaaaccg tgggtgttgc cgtaaacgta ttggtaatgg
     7441 ccggtttgca ccgccgcgcc ttcggagttt tcgatgcgct catcctcatt cagggcggct
     7501 tgttcgcatt gttttgccaa ctcgacggcg gcttccgtat ccaaatccca ttcgtggtaa
     7561 aggtcggggt cgccgatgtg ttttgccatc agacaggcat cggcaagtcc ggcgcaaccg
     7621 tcttcggcgg tgtggcgggc gatgtcggcg gcggcgcgga cggtgtcgcg cagggcttgt
     7681 tcggagaaat cggcggtgcc ggcgcggcct ttgcgtttgc cgacgtaaac ggtaatgtcc
     7741 agcgacttgt cctgctgaaa ctcgatttgt tcgatttcgc ccagccgcac gctgacgctt
     7801 tgtcccaatg attcgctgaa atcggcttcg gcggcggttg cgcccgtcgc ttttgccaag
     7861 tcgagcgtgc ggcggcagag gtcgaggagt tcggaagcgg tgtggttgaa cagcatagaa
     7921 atctttcttg atgatgcttt gcggcatttt aaccgtttcg ggcggcaggg gcaaaagcgc
     7981 gccgcttgca gggcgtgcgg tgcaaaatgc cgtctgaacg cggcggcatt ctgttaaaat
     8041 gcgctattgg aaaaaattcg agaaccaaga tgtttgaaca agaagacgag tggatcagta
     8101 aaacccaaat gaaaaagcag atgaacggtt tgcaggattt gggtatggaa ctgaccaagc
     8161 tctcaaacga tacgctgaaa aaaatcggct tggacgaaga tttgtacgaa gccgtcgtta
     8221 cctataaaaa aattacgtcc aacggcgcgc tcaagcggca ggcgcaattt atcggcaggc
     8281 tgatgcgcga cacggatccc gcgcccatcg aggcgtttct tgccaagctg cgcggcgacg
     8341 atgcggcgca caacgccttt ttgcaacgcg tggaacaggc gcgcgtacgg ctgttggcag
     8401 acgacggcgc gttgacgcag tttatgtcgg attttccgca tgcggacgcc ggtaaattgc
     8461 gtaccttgat ccgcaacacc aaaaaagagc aggagcaaaa caaaccgccg aaaaacttcc
     8521 gcgcgctgtt tcaagaattg aaaaccgtga tggaaaacgg ggacgcggaa atttaggcat
     8581 attttcagac gacatccgcc gttatttaga ttggaggata aaatgttgtt ccgtaaaacg
     8641 accgccgccg ttttggcggc aaccttgatg ctgaatggct gtacggcaat gatgtggggc
     8701 atgaacgacc cgttcagcca aacgaccgcc tataaacacg ttgacaaaga ccaaatccgc
     8761 gccttcggtg tggttgccaa agacaatgcc caattggaaa agggcagttt ggtgatgatg
     8821 ggcgggaaat actggttcgt cgtcaatccc gaagattcgg cgaagctgac gggcattttg
     8881 aagattgggt tagacaagcc cttccaaata gttgaggaca ccccgagcta tgcccgctac
     8941 caagccctgc cggtcaaact cgaatcgccc gccagccaga atttcagtac cgaaggcctt
     9001 tgcctgcgct acgataccga cagacctgcc gacatcgcca agctgaaaca gcttgagttt
     9061 gaagcggtcg aactcgacaa tcggaccatt tacacgcgct gcgtctccgc caaaggcaaa
     9121 tactacgcca caccgcaaaa actgaacgcc gattatcatt ttgagcaaag tgtgcctgcc
     9181 gatatttatt acacggttac gaaaaaacat accgacaaat ccaagttgtt tgaaaatatt
     9241 gcatatacgc ccaccacgtt gatactggat gcggtgggcg cggtgctggc cttgcctgtc
     9301 gcggcgttga ttgcagccac gaattcctca gacaaatgaa cggcaatgcc gtctgaaaag
     9361 ccttcagacg gcatttcaaa cacatccgca ctgtaaagtt ccacgctatg tccgtcaaaa
     9421 tccaaacccg atccgtcaat accaacgttt ttaatcattt gctcaccgcc ggtgccgatc
     9481 ctttaatcgc ccggctttgt gcctcgcgcg gtgtgcaaag tcctgccgaa ttggacgaca
     9541 agcttgctgc gcttttgccg tatcaaacgt tgacaaactg cgaagccgcc gccggccgtt
     9601 tggcggatgc ggttgagcgt caggaaaaaa tcctgattgt cgccgactac gatgccgacg
     9661 gcgcgacggc gtgttccgtc ggtatgagcg gtttggcggc gatgggggct aaagtggatt
     9721 tcctcgtacc caaccgcttt gaacacggct acggcttaac gcccgagctg gctgaaatcg
     9781 cggcagagca aggtgtggat ttgctgatta cggtcgataa cggtatcgcc agcatcgcag
     9841 gcgtggcgcg tgcgcaggaa ttgggtttgg atgtgattgt aaccgaccac catctgcctg
     9901 ccgagaccgt gccagactgc atcatcgtca atccgaacca aaaaggctgc ggtttccaaa
     9961 gcaaaagctt ggcgggcgtg ggcgtgattt tttatgtgtt gatggctttg cgtgccgaac
    10021 tgcgccgccg cgattatttt tcagacggca tcaaagagcc gaatctgggc gaccttttgg
    10081 atttggtcgc actcggtacc gtcgccgacg tcgttactct agaccacaac aaccgtatcc
    10141 tcgtgtcgca aggtttgaaa cggatgcgtt cgggcaaaat gcgccccggc atccgcgcct
    10201 tgtttgaagt ggcgcggcgc gattggcgca aggcgcagcc gtttgatatg ggttttgcgt
    10261 tgggcccgcg catcaacgcc gccggacggc tggacgatat gtcggtcggt attgcctgcc
    10321 tgttggcgcg agatgatacc gaggcgcagg aactggcggc gcagttaaac aacctcaata
    10381 tcgaacgtcg cgaaatcgag cagtctatgc tgcaagacgc gctgaatgct tttcctgaaa
    10441 ccctgccttc aggtcagatg actttggtgg cgtatcgcga cgacttccat caaggcgtgg
    10501 tcggcatcgt tgccagccgc ctcaaagacc gtttttatcg tccgaccatc gtgtttgcgc
    10561 ctgccgacaa cggtgaagtg cgcggttcgg ggcgttccat tcccaatctt cacttgcgcg
    10621 atgctttgga cttggtgtcc aaacgccatc ccgatttgat tttgaaattc ggcggacacg
    10681 cgatggcggc gggcttgagc atactcgaac acaacattcc cgcgtttcag acggcctttg
    10741 aagaagccgt gcgcgaaatg gtgtgcgaag acgatttgtc gcaaaccttc atcaccgacg
    10801 gcagcctgcc tgcacgcgac attacgctgg aacaggcgca aaaccttgct aaacacgttt
    10861 gggggcaggg cttcgcgccg ccgagtttta ccgacgagtt ccacgtcgtc cgccagcagc
    10921 ctttgggcgc ggaaggcaaa cacaaaaaag cgtggctgca aaaagacggc tgcgaatttg
    10981 aagcaatgtt ctggcggtgc agcgaagaca ttcccgaata catccgcacg gtttaccgcc
    11041 ccgttgccaa cgaatggcgc aacaatctcg aattgcagct gtatatcgat tactgggaag
    11101 ccgcgtagag gcggcggaac actgtttgaa tgtgatttct gttccttcat ttgcctgttt
    11161 gtacgacggg aatgttccca atcggagaag gtgcatcaaa tttcagactc cgccacaaaa
    11221 gcagggtctg atttttttgg agggcaatct gttataatga cgcgttgccg ccgcgagggc
    11281 ggcgtgattc ggacggcgta gtttctacgc cttttgttta tggttacggc atcttgcaaa
    11341 ccgcgcctga tgccgtctga acacggttgc ctgtggagat gccgctcttc gggtcagaat
    11401 atttatgctg aaaaaatggt tgaataagat gctgccttcc ggtcggagca gtaaaaaagc
    11461 ggaaagtaaa acggtcattc ctgccgaaag acacaacatc cgtgccgaaa tgttgagctt
    11521 tgccgccgaa aacgtcatac gccgcctgaa aggggcgggg tttcaggctt atgtggtcgg
    11581 cggcgcggtc agggacctgc tgctcggcat cgaacccaag gatttcgatg tggcaaccga
    11641 tgccacgccc gaacaggtgc acaaactctt ccgccgcagc cgcatcatcg gcaggcgttt
    11701 tcagattgtc catgtgatga acggtgcgga gattatcgaa gtaacgacgt ttcgcggcgg
    11761 tgcaaaggtt catcagaacg cgcacggcag aatcatgaag gacaacacct acggcagcat
    11821 cgaagaagat gcgatgcggc gcgattttac ctgcaatgcc ttgtattacg atcctgaaaa
    11881 agaagagatt ttggatttcc acaacgggat tgccgatgtt gccgcccaca ggctggttat
    11941 gattggcgat gccgccgaac gctatcagga agaccctgtc aggattttgc gcgccatccg
    12001 cctgtcgggc aaattgggct ttgatctgtc ggaagaaacc gccgcaccga ttgccgaatc
    12061 gatatgccgt ctgaagcacg aaccggtagc gaggctgttc gacgaaatta tgaaattgct
    12121 gttttcaggg cacgctcgcg agtgtctgaa acgtttgaac ggatttgaca taccggacga
    12181 catccatccg ctgctcaatg ctttgcgcgt ttcagacggc atcgccggaa aaatgacggt
    12241 gcttgccctg aaaaataccg atgagcggct gcgtgccgac aaatcggttt cggtcggttt
    12301 cgtactggcg gccctgatgt ggcccgagtt ggaacgccat tggaaaagca atctgcaaca
    12361 gggtttgaaa cccgtgcccg ccctgtccga tgcaatcaat acgatgcgcg aaaccgtcga
    12421 acgcggttgg ggcgtaccgc aacgcttttc cgccacgatg cgcgaaattt ggatgttcca
    12481 gccgcagttt gaaaatcgca aaggcgcacg tccgcacaaa ctgtttgcac aggcgcgttt
    12541 ccgtgccgcc tatgatttcc tgctcttgcg cgccgaaacc ggcaatgcgg accgcgccct
    12601 tgccgagtgg tggacggcgt ttcagacggc atcgacggaa cagcggtcgg agatgaccaa
    12661 aaacgaagcc gccgcccgac acgaaaaaaa cgaaggacag gcgaaaaaac gccgccgtcg
    12721 caggcgcaaa cccaagccga aggttgtggg aacggattgg gaataagggt caacagacaa
    12781 ggagcaatga agtttcaaca catgggatga agcataaagt gccgttctat gtattatcct
    12841 gatttgtaag gggattcatc cccgtaaata aagtctaacc ctgcctctcg gaaaaaggat
    12901 gtccgggtgg gcagggttca agaaacaagg aaaaattgat gaaaaaatgt attttgggca
    12961 ttttgaccgc gtgtgccgcc atgcctgcat ttgccgacag aatcggcgat ttggaagcac
    13021 gtctggcgca gttggaacac cgtgtcgccg tattggaaag cggcagcaat accgtcaaaa
    13081 tcgacctttt cggttcaaat tccaccatgt atgtatgcag cgttacgcct tttcagaaga
    13141 cgtttgaggc aagcgatcgg aatgaaggcg tggcgcggca gaaagtgcgt caggcgtgca
    13201 accgcgaaac ttcggcaatg ttttgcgaag atgaggcaat ccgatgcaga aaattcgatt
    13261 gatgtatcgg ttggacggat aaagaaacgg atacggatac ggagcttggc ttccgtatct
    13321 gtttttctct gcccgatttt ccatgcatcg ggtttcagac ggcattggaa tgtcagtcgt
    13381 gttctgccga ttcgtaggct tcgacgattt tttgcaccaa aggatgccgg acaacgtctt
    13441 cgccggtaaa ggtgtggaaa tacagccctt ccacgccgtg cagtttctca cgcgcatctt
    13501 ttaatcccga tttgatgttt ttgggcaggt cgatttggct ggtgtcgccg gtaatgacgg
    13561 ctttcgcgcc gaagccgatg cgggtcagga acattttcat ttgttcgggc gtggtgtttt
    13621 gcgcttcgtc gaggatgatg tatgcgccgt tgagcgtcct gccgcgcata taggcgagcg
    13681 gggcgatttc aatcaggcct ttttcaatca gcttggtgac acggtcaaag cccatcaggt
    13741 catagagggc atcataaagc ggacgaaggt agggatcgac tttctgggtc aggtcaccgg
    13801 gcagaaaacc cagtttctcg ccggcttcga cggcaggccg cactaaaatg atgcgttcga
    13861 cttggtgttt ttccatcgca tcgacggcgg cggcgacggc gagataggtt ttgcccgtac
    13921 ctgccggccc gagaccgaat acgatgtcgt ggttgagtag ggcgcggata tagccgttct
    13981 gccgtggcgt tctgccgccg atgctgccgc gcttggtgcg gaaataatag gcgtggtcat
    14041 ggtttttttc ttgatgaccg gcatcttcgg tttgggcttc gacggcggca agcctgatgt
    14101 cgccgtcgtt taggtcgcgc gtctgcgccg tttccaagag tttgagcagt gcgcgtttgc
    14161 cggcgtgtgc aaatgcgccg ttgaaagtga aatgttcaaa acggcggctg atgtggatat
    14221 cgagtgcttt agcaagtaaa tcaaggttgt tgtcaaaaga accgcacaga cgctgcaacg
    14281 ccaagttgtc ggtttcttct aaatgcaggt ggacggtatg tgtcatatga aggtccgaat
    14341 agttggatat tgtgtgattt taatctatag tggatta
//
LOCUS       DAXIDM010000046        13638 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000046 DAXIDM010000000
VERSION     DAXIDM010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 13638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13638
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.046"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            228..344
                     /locus_tag="ACFOAE_001154"
                     /pseudo
     CDS             228..344
                     /locus_tag="ACFOAE_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            354..1323
                     /locus_tag="ACFOAE_001155"
                     /pseudo
     CDS             354..1323
                     /locus_tag="ACFOAE_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225028.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter six-transmembrane
                     domain-containing protein"
     gene            complement(1374..2426)
                     /gene="sohB"
                     /locus_tag="ACFOAE_001156"
     CDS             complement(1374..2426)
                     /gene="sohB"
                     /locus_tag="ACFOAE_001156"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HFC6884653.1"
                     /translation="MWKEILLNYGIFLLELLTVFGAIALIVLAIVQSKKQSESGSVVL
                     TDFSENYKKQRQSFEAFFLSGEEAKHQEKEEKKKEKAEAKAEKKRLKEGGEKSSETQK
                     SRLFVLDFDGDLYAHAVESLRHEITAVLLIAKPEDEVLLRLESPGGVVHGYGLAASQL
                     RRLRERNIPLTVAVDKVAASGGYMMACVADKIVSAPFAIVGSVGVVAEVPNIHRLLKK
                     HDIDVDVMTAGEFKRTVTFMGENTEKGKQKFRQELEETHQLFKQFVSENRPQLDIEEV
                     ATGEHWFGRQALALNLIDEISTSDDLLLKAFENKQVIEVKYQEKQSLIQRIGLQAEAS
                     VEKLFAKLVNRRADVM"
     gene            complement(2530..2619)
                     /locus_tag="ACFOAE_001157"
     tRNA            complement(2530..2619)
                     /locus_tag="ACFOAE_001157"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2583..2585),aa:Leu,seq:taa)
     gene            complement(2722..2795)
                     /locus_tag="ACFOAE_001158"
     tRNA            complement(2722..2795)
                     /locus_tag="ACFOAE_001158"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2761..2763),aa:Cys,seq:gca)
     gene            complement(2821..2896)
                     /locus_tag="ACFOAE_001159"
     tRNA            complement(2821..2896)
                     /locus_tag="ACFOAE_001159"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2861..2863),aa:Gly,seq:gcc)
     gene            complement(2918..2993)
                     /locus_tag="ACFOAE_001160"
     tRNA            complement(2918..2993)
                     /locus_tag="ACFOAE_001160"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2958..2960),aa:Gly,seq:gcc)
     gene            complement(3017..3092)
                     /locus_tag="ACFOAE_001161"
     tRNA            complement(3017..3092)
                     /locus_tag="ACFOAE_001161"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3057..3059),aa:Gly,seq:gcc)
     gene            complement(3118..3193)
                     /locus_tag="ACFOAE_001162"
     tRNA            complement(3118..3193)
                     /locus_tag="ACFOAE_001162"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3158..3160),aa:Gly,seq:gcc)
     gene            complement(3273..3836)
                     /gene="pgsA"
                     /locus_tag="ACFOAE_001163"
     CDS             complement(3273..3836)
                     /gene="pgsA"
                     /locus_tag="ACFOAE_001163"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFC6884654.1"
                     /translation="MPWNLPIFLTWLRVLLIPVMTALFYLPFPWFAEETINLTAAVIF
                     AVAALTDWFDGFLARLWKQTSDFGAFLDPVADKLMVAVSLLLLVKLDRTYVLFAMIII
                     GREITISALREWMAQMGKRNSVAVATVGKFKTAAQMLAIFLLLLNIPDFYGFNLVVIG
                     NVLMFIASLLTVWSMLYYLKMAWKEIA"
     gene            complement(3942..4365)
                     /locus_tag="ACFOAE_001164"
                     /pseudo
     CDS             complement(3942..4365)
                     /locus_tag="ACFOAE_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4695..5030)
                     /locus_tag="ACFOAE_001165"
     CDS             complement(4695..5030)
                     /locus_tag="ACFOAE_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003699221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFC6884655.1"
                     /translation="MFKDWKEHTALVKKSFGELGKAHPKMLQAYGALEQAAAAEALDA
                     KTRELIAIAVAITTRCESCISVHAAAAAKAGATDSEIAGALATAIALNAGAAYTYALR
                     ALEAVETQK"
     gene            5159..6064
                     /gene="mtrA"
                     /locus_tag="ACFOAE_001166"
     CDS             5159..6064
                     /gene="mtrA"
                     /locus_tag="ACFOAE_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter MtrCDE transcriptional
                     activator MtrA"
                     /protein_id="HFC6884656.1"
                     /translation="MDILDKLVDFAQLTGSVDVQCLLGGQWSVRHETLQREGLVHIVT
                     SGSGYLCIDGETSPRPVSTGDIVFFPRGLGHVLSHDGKCGESLQPDMRQHGAFTVKQC
                     GNGQDMSLFCARFRYDTHADLMNGLPETVFLNIAHPSLQYVVSMLQLESKKPLTGTVS
                     MVNALSSVLLVLILRAYLEQDKDVELSGVLKGWQDKRLGHLIQKVIDKPEDEWNVDKM
                     VAAANMSRAQLMRRFKSRVGLSPHAFVNHIRLQKGALLLKKNPDSVLSVALSVGFQSE
                     THFGKAFKRQYHVSPGQYRKEGGQK"
     gene            complement(6126..6614)
                     /locus_tag="ACFOAE_001167"
     CDS             complement(6126..6614)
                     /locus_tag="ACFOAE_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFC6884657.1"
                     /translation="MKKYLIPLSIVAVLSGCQSIYVPTLTEIPVNPINTVKTEAPAKG
                     FRLASSHWTDVAKISDEATRLGYQVGIGKMTKVQAAQYLNNFRKRLVGRNAVDDSMYE
                     IYLRSAIDSQRGAINTEQSKLYIQNALRGWQQRWKNMDVKPNNPAFTNFLMEVMKMQP
                     LK"
     gene            6761..7663
                     /locus_tag="ACFOAE_001168"
     CDS             6761..7663
                     /locus_tag="ACFOAE_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC6884658.1"
                     /translation="MDTAKKDILGSGWMLVAAACFTIMNVLIKEASAKFALGSGELVF
                     WRMLFSTVALGAAAVLRRDTFRTPHWKNHLNRSMVGTGAMLLLFYAVTHLPLATGVTL
                     SYTSSIFLAVFSFLILKERISVYTQAVLLLGFAGVVLLLNPSFRSGQETAALAGLAGG
                     AMSGWAYLKVRELSLAGEPGWRVVFYLSVTGVAMSSVWATLTGWHTLSFPSAVYLSCI
                     GVSALIAQLSMTRAYKVGDKFTVASLSYMTVVFSALSAAFFLAEELFWQEILGMCIII
                     LSGILSSIRPTAFKQRLQSLFRQR"
     gene            complement(7704..8834)
                     /locus_tag="ACFOAE_001169"
     CDS             complement(7704..8834)
                     /locus_tag="ACFOAE_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6884659.1"
                     /translation="MTKHLPLAVLTALLLAACGGSDKPPAEKPAPAENRNVLKIYNWS
                     EYVDPETVADFEKKNGIKVTYDVYDSDETLESKVLTGKSGYDIVAPSNAFVGRQIKAG
                     AYQKIDKSLIPNYKHLNPEMMRLMDGVDPGHEYAVPFYWGTNTFAINTERVKKALGTD
                     KLPDNQWDLVFDPEYTSKLKQCGISYLDSAAEIYPMVLNYLGKNPNSSNTEDIREATA
                     LLKKNRPNIKRFTSSGFIDDLARGDTCVTIGFGGDLNIAKRRAEEAGGKEKIRVMMPK
                     EGVGIWVDSFVIPKDAKNVANAHKYINDFLDPEVSAKNGNFVTYAPSSKPARELMEDE
                     FKNDNTIFPTEEDLKNSFIMVPIQPAALKFMVRQWQDVKAGK"
     gene            9039..11663
                     /gene="alaS"
                     /locus_tag="ACFOAE_001170"
     CDS             9039..11663
                     /gene="alaS"
                     /locus_tag="ACFOAE_001170"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFC6884660.1"
                     /translation="MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQ
                     FKDVFLGFDKRPYSRATTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFK
                     RDAIHFAWEFLTSPEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKG
                     AKYVSDNFWQMGDTGPCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFN
                     RDEQGNMNPLPKPSVDTGMGLERMAAVMQHVHSNYEIDLFQDLLKAVARETGAAFSMD
                     EPSLKVIADHIRSCSFLIADGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLV
                     ADLVKEMGDAYPELKEKQVQIEEALKNEESRFAQTLETGMALLENALAKGGKTLDGEI
                     IFKLYDTYGFPYDLTADICRERNIELDEAGFEREMEAQRARARAAQSFKANAQLPYDG
                     QDTEFKGYSERQTESKVLALYKDGEQVDELNEGDSGAVVIDFTPFYAESGGQVGDVGY
                     IFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATH
                     LMHKALRDVLGEHVEQKGSLVTAESTRFDISHPQAVTAEEIAEVERRVNEAILANVAV
                     NAAIMSMEDAQKTGAMMLFGEKYGDEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIIS
                     EGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETKAQTEKDVLAKIQAGAAHAKA
                     LEKELAKAKAELAVHAGAKLLDDAKDLGAAKLVAAQIEADAAALREIVTDLTGKSDNA
                     VILLAAVNDGKVSLCAGVSKPLTGKVKAGDLVKFAAEQVGGKGGGRPDLAQAGGTDAG
                     KLPEMLVSVESWLCQKLS"
     gene            11725..12456
                     /locus_tag="ACFOAE_001171"
     CDS             11725..12456
                     /locus_tag="ACFOAE_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884661.1"
                     /translation="MNTKTELQKLLEEDISTLTETLICADALPPRYVRSIATPIVRRW
                     LIDKQLNILAKEIGLTIELPILDTSLVFEKLSTLENKVNFYMAGGVYLGGEFISSIYH
                     SSQEFSGEPIIYAEPNIILCPAEKFLTLKRVFHNGNIFNMNQIITFLSNKQGGVHFDK
                     NYDKYKTWQVAIEKAANFLKLGNPYNEDKLSLSEEHDTILVVLPLEKGYEWNCLEIEV
                     LSAAQSLANIYCNKVRLIDGHVWKE"
     gene            12763..>13638
                     /locus_tag="ACFOAE_001172"
     CDS             12763..>13638
                     /locus_tag="ACFOAE_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IIL restriction-modification enzyme MmeI"
                     /protein_id="HFC6884662.1"
                     /translation="MKTLLQLQTAAQNFAAYYKDQTDERREKDTFWNEFFAIFGIDRK
                     NVAHFEYPVKDPADNTQFVDIFWEGIFLAEHKSANKNLTKAKEQAERYLQEIGRTKPS
                     ALPEYYAVSDFAHFHLYRRVPEEGVENQWQFPLEALPEYITRGVFDFMFGIEAKVRQI
                     QEEADIQAAAAIGRLHDALKEEGIYEEHELRLFITRLLFLFFADDSAVFQRNYLFQDF
                     LESCKETDTLGDKLNQLFEFLNTPDQKRSKTQSEKFKGFEYVNGGLFKERLRTFDFTA
                     KQHRALIDCGNFDWRN"
BASE COUNT         3450 a         3539 c         3280 g         3369 t
ORIGIN      
        1 tcaaagtgag tgcacaaagc catctgaagg cgatgtgttt gaacctgttg aaagccgcca
       61 acaggctaag tgcgcccgct gccgcctaaa aggcagcacg gatgcctgat tatcgggtat
      121 ccggggagga ttaagggggt atttgggtaa aattaggagt gatttgaggt gaaaacagcc
      181 gaaaacctgt gttgggattt cggttgtcgt gagggaaagg aattttgcaa aggtctcaca
      241 aagtatttgc cacattcggc gacaagcgca caactcggct gtttgccgat ttggatgcac
      301 tggcggaagt gatggaaaaa acaatctcgg aaaataaaaa atagggagca aagatgtgga
      361 aaatgttgaa acacatagcc aaaaccaccg caagcgattg attggcacat tttttctggt
      421 cggactggaa aaccttttga tgctggtgta tccggtgttt ggcggctggg caattaatgc
      481 cgtaattgcg gggaaggtgt ggcaggcgtt gctgtacgct ttggttgtgc ttttaatgtg
      541 gctggtcggt gcggcgcggc ggattgccga tacacgcacg tttacgcgga tttataccga
      601 aatcgccgtg ccggttgtgt tggaacagcg gcagcggtaa gtcccgcatt cggcaatata
      661 gtggattaaa tttaaaccag tacggcgttg tctcgccttg ccgtactatt tgtactgtct
      721 gcggcttcgt cgccttgtcc tgatttttgt taatccacta taactgcacg ggttgccctg
      781 tcgcgtgagt ttgtcagctt ttttgaagaa cacctgccga ttgccgcgac atccgtcgta
      841 tccatattcg gcgcgtgcat catgctgctg gtgctggaat tttgggtcgg cgtgtcggcg
      901 gtgggcatac ttgcgttgtt tttatggctt ttgccacgtt ttgccgccat cagcgaaaac
      961 ctgtatttcc gcctgaagaa cagcttggaa cgcgacaacc actttatccg aaaaggcgac
     1021 cggcggcagc tgtaccgcca ttacggactg cttgcgcgcc tgcgtgtgct gatttccaac
     1081 cgcgaagcct tcggctatct ctgcgtcggc acggcgatgg gtattttgtt cggctttgct
     1141 tttgtgatga tgacgctcaa aggctacagc agcgcggggc atgtctattc ggtcggcact
     1201 tatctgtgga tgtttgccat gagtttggac gacgtgccgc gattggtcga acaatattcc
     1261 aatttgaaag acatcggaca acggatagag tggtcggaac ggaacatcaa agccggaact
     1321 tgaaaaatgc cgtctgaaca cgcttcagac ggcatttcca tccgttcggc aaactacatc
     1381 acatccgccc gccggttgac aagtttggca aacaactttt caacagaagc ttccgcctgc
     1441 aaaccaatgc gctggatcag gctttgcttc tcctgatatt tcacttcgat aacctgtttg
     1501 ttttcaaacg ctttcaacaa caaatcatca ctggtcgaaa tctcgtcaat caagttcaac
     1561 gccaacgcct gccgaccgaa ccaatgctcg cccgttgcca cttcctcaat atccaattga
     1621 gggcggttct cgctgacaaa ctgcttgaac aactgatgcg tttcctccag ttcctgtcgg
     1681 aatttctgtt tgcccttttc cgtattttca cccataaaag taaccgtgcg cttaaattcg
     1741 cccgccgtca tcacatccac atcaatatca tgttttttca acaggcggtg gatattcggt
     1801 acttccgcca ccacacccac cgaaccgaca atcgcaaacg gagcggaaac aattttatcc
     1861 gccacacacg ccatcatata accaccgctc gctgccacct tatcgacggc gacggtcagc
     1921 ggaatattgc gttcgcgcaa acgcctaagc tgcgaagccg ccaaaccgta accgtgaacc
     1981 acgccgcccg gactttccaa tctaagcaga acctcatctt caggcttggc aatcaaaagc
     2041 accgccgtaa tctcatgacg caaggattct acggcgtgtg catacaaatc gccgtcaaaa
     2101 tccaacacaa aaaggcggga tttttgcgtt tcggaagatt tctccccacc ctccttcaaa
     2161 cgctttttct ctgctttggc ttccgccttt tcctttttct tttcctcttt ttcctgatgt
     2221 tttgcctctt ccccgcttaa aaagaatgct tcaaacgatt gccgctgttt tttataattt
     2281 tccgaaaaat ccgtcagtac gacactgccg ctttccgact gtttcttact ctgtacgata
     2341 gccaacacaa tcagcgcaat tgcgccgaac acggtaagca gttcgagcag gaaaataccg
     2401 taattcagta aaatttcttt ccacattgat tggatttcct cttgttcagg catgaacatg
     2461 tcaatattgt ccatcaccgt ccgacagata aaaaaataac cgcttggagc ggcattgtca
     2521 ttttcagctt ggtgcccgga gccggaatcg aaccggcacg ggatgtttag tcccgacgga
     2581 ttttaagtcc gttgtgtcta cctatttcac cacccgggca tttgtgaaag gtggaggcgg
     2641 gggcgcggat tttaaccggc ctatatgaag attgcactcc tcatagcata aacactctgc
     2701 caccccgccg tagtacgata atggaggcga gagtcggaat cgaaccggcg tagacggatt
     2761 tgcaatccgc tgcataacca ctttgctatc tcgccctaaa actggcttat ctaaaaaact
     2821 tggagcggga aacgagtctc gaactcgcga cctcaacctt ggcaaggttg cgctctacca
     2881 actgagctat tcccgcgcgt tcaaacatat cggtttttgg agcggaaaac gagtctcgaa
     2941 ctcgcgacct caaccttggc aaggttgcgc tctaccaact gagctattcc cgcgttgata
     3001 tgtttgaaat aaaacttgga gcgggaaacg agtctcgaac tcgcgacctc aaccttggca
     3061 aggttgcgct ctaccaactg agctattccc gcaatgattg tgggaaaatg aaatttttgg
     3121 agcgggaaac gagtctcgaa ctcgcgacct caaccttggc aaggttgcgc tctaccaact
     3181 gagctattcc cgcccgattt cattctccaa catcgaagag acgcaattat tatggattct
     3241 gtttttgccg tcaagctatt tttatgtttt tttcaggcga tttctttcca cgccattttc
     3301 agataataca gcatcgacca gactgtcagc aaagatgcga taaacatcaa tacattgccg
     3361 ataacaacaa gattaaatcc gtaaaaatcg ggaatattca gcagcagcag gaaaattgcc
     3421 agcatttgcg cggcggtttt gaacttaccg acggtggcga cggcaacgct gttccttttg
     3481 cccatttgcg ccatccattc gcgcaatgcg gaaatggtaa tttccctgcc gataatgatc
     3541 atggcaaaca aaacataggt cctgtcgagt ttgaccagta aaagtagcga tacggcaacc
     3601 atcagcttgt cggcgacggg atcgaggaag gcgccgaaat cggaagtctg tttccacagt
     3661 cttgccaaaa atccgtcaaa ccagtcggtt aaggcggcaa cggcaaaaat gacggcggcg
     3721 gtgagattaa tcgtttcctc cgcgaaccac ggaaaaggca ggtaaaaaag ggctgtcatg
     3781 acaggaatga gcaagaccct caaccatgtg aggaagatag ggagattcca aggcatcggt
     3841 tttctctgtg cagactgtaa agttgtgatt ataacggtta tcctcataac ccaaaacgta
     3901 aaattgctgc atgggcattc ccccgccccg ccaatctgtt ttcacattct tttcaaacgc
     3961 aggaaaatgg cgggcaataa aagcaaaata cccagtttca ggcagaaaac ggcaggttgt
     4021 gccaacactt cgacaaggcg gtcttccgtg cgggcaaaat ctttattgct tatagacact
     4081 gccactgttg cggtattcca acagaacgcc gtttaaaaaa cctttgccga cggtttcgct
     4141 taaaacggct ctaacctgct ccgccctgat ggttctgccg atattgccgc ctgtgcacaa
     4201 actgtcgaac ccatagcagg aaagccggta atgctgcccg tctgcatcca gtttgattgc
     4261 ccgtccgctg cggttggggg cggtaacggt caattccgca tattcgaatg ttttttcttg
     4321 ttcgtgaaat gccgtcaggt aaggtgcaat aaaaacggcg gacaacagca gacagcttat
     4381 ggcggcaaac catacccagc ggtgatatag tggattaaca aaaaccagta cagcgttgcc
     4441 tcgccttagc tcaaagagaa cgattctcta aggtgctgaa gcaccaagtg aatcggttcc
     4501 gtactatttg tactgtctgc ggcttcgtcg ccttgtcctg atttttgtta atccactata
     4561 tttcacgctt accccttgtt tctcaaatgc cgtctgaaat aagcggctta atatattgtt
     4621 tacagtattg ggaagcataa cagacaaaat gccgtctgaa atattttcag acggcatttc
     4681 ttatccgaaa cggattattt ttgcgtttca accgcttcca atgcacgcag ggcgtaagtg
     4741 taagcggcac cggcattcag ggcgatggcg gttgccaatg cgcctgcgat ttcgctgtcg
     4801 gtcgcaccgg ctttggcggc agcggcggcg tgaacgctga tgcagctctc gcaacgagtg
     4861 gtaatggcaa cggcgatggc aatcagttcg cgcgttttgg catcaagtgc ttcggcggcg
     4921 gcggcctgtt ccaatgcgcc gtaggcctgc agcattttag gatgcgcctt acccagctcg
     4981 ccgaacgatt ttttaaccaa tgcggtatgt tctttccaat ctttaaacat tttcttttcc
     5041 tttctcttgc gtttaaccct gatacgcgct tgcgtatctg ttttcgatgt gcgtattatt
     5101 gcaattattc agttgtgttt ctcgtttaat catctcattt tatggttcaa aaagatttat
     5161 ggacattctg gacaaactgg tcgatttcgc ccaattgacg ggcagtgtgg atgtgcagtg
     5221 ccttttgggc ggacaatggt cggtacggca tgaaaccttg caacgcgaag gattggtaca
     5281 cattgttaca tcgggcagcg gctatctctg catcgacggc gaaacttccc cgcgtccggt
     5341 cagtacaggg gatattgtat ttttcccgcg cggcttgggt catgtgttga gccacgacgg
     5401 aaaatgcgga gaaagtttac aaccggatat gcggcagcac ggtgcgttta cggtcaagca
     5461 gtgcggcaac ggacaggata tgagcctgtt ttgcgcccgt ttccgctacg acacccacgc
     5521 cgatttgatg aacgggctgc ctgaaaccgt ttttctgaac attgcccatc cgagtttaca
     5581 gtatgtggtt tcaatgctgc aactggaaag caaaaaacct ttgacgggga cggtttccat
     5641 ggtcaacgca ttgtcgtccg tcctgctggt gcttatcctg cgcgcctatc tcgaacagga
     5701 taaggatgtc gaactctcgg gcgtattgaa aggttggcag gacaaacgtt tgggacattt
     5761 aatccaaaag gtgatagaca aaccggaaga cgaatggaat gtcgacaaaa tggtggcggc
     5821 tgccaatatg tcgcgcgcgc aactgatgcg ccgtttcaaa agccgggtcg gactcagccc
     5881 gcacgccttt gtgaaccata tccgcctgca aaaaggcgcg ttgctgctga aaaaaaaccc
     5941 ggattcggtt ttgtcggtcg cactgtcggt aggctttcag tcggaaacgc acttcggcaa
     6001 ggcgttcaaa cggcaatatc acgtttcgcc gggtcaatac cggaaagaag gcgggcaaaa
     6061 ataaatcggg gcttcaaacg caaatgccgt ctgaaaaggc tttcatacag catttgcgta
     6121 ccgcgtcatt tcaagggctg catcttcatc acttccatca aaaagttggt aaatgcgggg
     6181 ttgttgggtt tgacatccat atttttccaa cgctgctgcc agccgcgcaa ggcattctgg
     6241 atatacagct tggactgttc cgtattgatt gcgccccgct ggctgtctat cgccgaacgc
     6301 aggtagattt catacatact gtcatcgacg gcattgcgtc cgaccaggcg ttttctgaag
     6361 ttgttcagat attgcgccgc ctgaaccttg gtcattttac cgatacccac ctgatagccc
     6421 aagcgcgtcg cttcatcgct gattttggca acatccgtcc aatgcgaaga ggcaaggcgg
     6481 aaaccttttg caggtgcttc cgttttgacg gtattgatag gattcacggg gatttccgtc
     6541 aatgtgggca cataaataga ctggcagccg gaaagaactg ccacaatgga aagagggata
     6601 aggtattttt tcatgccccc attataatca agtttgcctt gagaaaacaa attgttcggc
     6661 aagaaaaata aaatttcggc atcagaagca ggcaaaaaca cattccacaa gccttgccgc
     6721 aaggtttaca atccgaccgt ccttatcgca acgaccgttt atggataccg caaaaaaaga
     6781 cattttagga tcgggctgga tgctggtggc ggcggcctgc ttcaccatta tgaacgtatt
     6841 gattaaagag gcatcggcaa aatttgccct cggcagcggc gaattggtct tttggcgcat
     6901 gctgttttca accgttgcgc tcggggctgc cgccgtattg cgtcgggaca ccttccgcac
     6961 gccccattgg aaaaaccact taaaccgcag tatggtcggg acgggggcga tgctgctgct
     7021 gttttacgcg gtaacgcatc tgcctttggc caccggcgtt accctgagtt acacctcgtc
     7081 gatttttttg gcggtatttt ccttcctgat tttgaaagaa cggatttccg tttacacgca
     7141 ggcggtgctg ctccttggtt ttgccggcgt ggtattgctg cttaatccct cgttccgcag
     7201 cggtcaggaa acggcggcac tcgccgggct ggcgggcggc gcgatgtccg gctgggcgta
     7261 tttgaaagtg cgcgaactgt ctttggcggg cgaacccggc tggcgcgtcg tgttttacct
     7321 ttccgtgaca ggtgtggcga tgtcgtcggt ttgggcgacg ctgaccggct ggcacaccct
     7381 gtcctttcca tcggcagttt atctgtcgtg catcggcgtg tccgcgctga ttgcccaact
     7441 gtcgatgacg cgcgcctaca aagtcggcga caaattcacg gttgcctcgc tttcctatat
     7501 gaccgtcgtt ttttccgctc tgtctgccgc attttttctg gccgaagagc ttttctggca
     7561 ggaaatactc ggtatgtgca tcatcatcct cagcggtatt ttgagcagca tccgccccac
     7621 tgccttcaaa cagcggctgc aatccctgtt ccgccaaaga taaaaaatgc cgtccgaaca
     7681 tccttcagac ggcatatcgg gctttatttc cccgccttca catcctgcca ctggcgcacc
     7741 ataaacttca atgccgccgg ctggataggc accatgataa agctgttttt caaatcctcc
     7801 tcggttggga aaatcgtatt gtcgttttta aattcgtctt ccatcagctc acgcgcaggc
     7861 ttgctcgaag gcgcgtaagt aacgaaattg ccgtttttcg ccgacacttc cgggtcgagg
     7921 aagtcgttga tgtatttgtg cgcgttggcg acgtttttcg catctttcgg aatcacgaaa
     7981 gaatccaccc aaatccccac gccctctttg ggcatcatca cgcggatttt ttccttgccg
     8041 cccgcttctt cggcacggcg tttggcgatg ttcaaatcgc cgccgaaacc gattgttacg
     8101 caggtatcgc cgcgcgccaa atcatcgata aagccggacg aagtaaagcg tttgatattg
     8161 gggcggtttt tcttgagtag ggcggttgcc tccctgatgt cttccgtatt gctgctgttc
     8221 gggtttttac ccaaatagtt caacaccata ggatagattt ccgccgcgct gtccaaatag
     8281 ctgatgccgc attgcttgag tttggacgtg tattcggggt cgaacaccaa atcccactgg
     8341 ttgtccggca gcttgtccgt acccaaagcc tttttcacgc gttcggtatt gatggcgaag
     8401 gtatttgtcc cccaataaaa cggcacggcg tattcgtggc cgggatcgac cccgtccatc
     8461 agcctcatca tttcggggtt gaggtgttta taattgggaa tcagcgactt atcgattttc
     8521 tgatacgcac ctgccttaat ctgcctgccc acaaacgcat tggacggcgc gacaatgtcg
     8581 taaccggact tgcctgtcag caccttgctt tccagcgttt catcgctgtc gtacacatca
     8641 taagtaacct tgatgccgtt tttcttttca aaatcggcaa cggtttccgg atcgacgtat
     8701 tccgaccagt tgtaaatttt caatacgttt cggttttccg ccggcgccgg tttttcggca
     8761 ggcggtttgt ccgaaccgcc gcacgctgca agcagcaaag cagtcaggac ggccaggggc
     8821 agatgtttgg tcattatcat tccttgcata tcgggttgga gaaagcggcc attatagccg
     8881 atattggcaa cagggcttca gacggcattc aaaatcccgc cacactcttc cgaaaaccgc
     8941 cgcttccata gctagaaaca gggatttgcg gtaagatacc gccgttcgtt ttccctgctt
     9001 ttaccatgac aagacatttg agagacattg aaaaaattat gaaaacctcc gaactgcgcc
     9061 aaaaattcct aaaatttttt gaaaccaaag gccacaccgt cgtccgctct tccagcctcg
     9121 tgccgcacga cgacccgacc ctgctgttta ccaacgcggg catgaaccag tttaaagacg
     9181 tattcttagg tttcgacaaa cgcccgtaca gccgcgccac caccgcgcaa aaatgcgtac
     9241 gcgcaggcgg caagcacaac gacttggaaa acgtcggcta caccgcccgc caccacacct
     9301 tctttgaaat gatgggcaac ttctccttcg gcgactactt caaacgcgac gccatccact
     9361 tcgcttggga atttctgact tccccggaat ggttgaacat ccctaaagac aaactgttgg
     9421 cgaccgttta cgcggaagac gacgaagcct acaacatctg gttgaacgaa atcggtatgc
     9481 cgtccgagcg catcgtccgc atcggcgaca acaaaggcgc gaaatacgtg tccgacaact
     9541 tctggcaaat gggcgacacc ggcccttgcg gcccctgctc cgaaattttc tacgaccacg
     9601 gcgaagaaat ctggggcggc attcccggca gccccgaaga agacggcgac cgctggatcg
     9661 aaatttggaa ctgcgtattt atgcagttca accgcgacga acaaggcaat atgaatccgc
     9721 tgcccaagcc gtccgtcgat accggtatgg gcttggaacg tatggccgcc gtcatgcagc
     9781 atgttcacag caactacgaa atcgacttgt tccaagacct gctcaaagcc gttgcccgcg
     9841 aaaccggcgc agctttcagc atggatgaac ccagcctgaa agtcatcgcc gaccacatcc
     9901 gctcctgctc gttcttgatt gcagacggcg tgttgccttc caacgaaggc cgcggctacg
     9961 tattgcgccg catcatccgc cgcgccgtgc gccacggtta caaactgggt caaagcaaac
    10021 cgttcttcca caaactggtg gccgatttgg tcaaagagat gggcgatgcc taccctgaat
    10081 tgaaagaaaa acaagttcaa atcgaagaag cgttgaaaaa cgaagaaagc cgttttgccc
    10141 aaacgctgga aaccggtatg gctttgttgg aaaacgcgtt ggctaaaggc ggcaaaacac
    10201 tcgacggcga aatcatcttc aaactctacg atacttacgg tttcccatac gatttgaccg
    10261 ccgacatctg ccgcgaacgc aatatcgaac tggacgaagc aggcttcgag cgcgaaatgg
    10321 aagcccaacg cgcacgcgca cgcgccgccc aaagcttcaa agccaacgcc caactgcctt
    10381 atgacggtca agacaccgag tttaaaggtt atagcgaacg ccaaaccgaa tccaaagtcc
    10441 tcgccctcta caaagacggc gagcaagtcg acgaattgaa cgaaggcgac agcggcgcag
    10501 tcgtcatcga ctttaccccg ttctatgcag aatccggcgg ccaagtcggc gacgtcggct
    10561 atatcttctc aggcgaaaac cgctttgaag tacgcgatac ccaaaaaatc aaagcagccg
    10621 tattcggcca attcggtgta caaacttcag gccgtctgaa agtcggcgac agcgttaccg
    10681 ccaaagtgga cgacgaaatc cgcaatgcca atatgcgcaa ccacagcgcg acccacctga
    10741 tgcacaaagc cctgcgcgac gtattgggcg aacacgtcga acaaaaaggc tctttggtta
    10801 ccgccgaatc cacccgtttc gacatttccc atccccaagc ggtaactgcc gaagaaattg
    10861 ccgaagtcga acgccgcgtc aacgaagcca ttttggcgaa cgttgccgtc aatgcagcca
    10921 ttatgagcat ggaagacgcg caaaaaaccg gcgcgatgat gcttttcggc gaaaaatacg
    10981 gcgacgaagt gcgcgtactg caaatgggcg gtttctcaac cgaattgtgc ggcggcacac
    11041 acgtttcacg caccggcgac atcggcctct tcaaaatcat cagcgaaggc ggtattgccg
    11101 caggcgtgcg ccgtatcgaa gccatcaccg gcctgaacgc actcaaatgg gcgcaagagc
    11161 aagagcgttt ggtgaaagac attattgctg aaaccaaagc ccaaaccgaa aaagacgtac
    11221 tggcgaaaat ccaagcaggc gcggcacacg ccaaagcctt ggaaaaagag ttggcaaaag
    11281 ccaaagccga actcgccgtc cacgcaggcg caaaactctt ggacgacgca aaagacttgg
    11341 gcgcagccaa actcgttgct gcccaaatcg aagccgacgc agccgccctg cgcgaaatcg
    11401 ttaccgattt aaccggtaaa tccgacaacg ccgtgattct tttagcggca gtaaacgacg
    11461 gcaaagtctc cctgtgcgcc ggcgtatcca aaccgttgac cggcaaagtg aaagcaggcg
    11521 atctggttaa atttgcagcc gaacaagtcg gcggcaaagg aggcggccgt cccgacttgg
    11581 cgcaggccgg cggcacggat gccggcaaat tgcccgaaat gctggtaagc gtggaaagct
    11641 ggctttgtca gaaattaagt taaatttaaa tcttaataag ccatttgagt cttgttcaaa
    11701 tggcttatat tttggattgt tagaatgaat actaaaacag agttacaaaa acttttagaa
    11761 gaggatatat caactttaac agaaacacta atttgtgcag atgctcttcc tccaagatat
    11821 gtacgtagca ttgcaactcc tattgtccgt cgatggttaa ttgacaaaca attaaatatt
    11881 ctcgcaaaag aaataggttt aactatagaa ttgcccatcc ttgatacaag tttggtattt
    11941 gaaaaattgt caaccttaga gaataaagtt aatttttata tggctggtgg agtttattta
    12001 ggcggagaat ttattagctc tatatatcat tcatcacaag aattttctgg tgaaccaata
    12061 atctatgctg aaccaaatat aattttatgt cctgctgaaa aatttttaac tttaaaacga
    12121 gttttccata atggaaatat ttttaatatg aatcagataa ttactttttt atccaataaa
    12181 caaggaggag tacattttga taaaaattac gataaatata aaacttggca agttgctata
    12241 gaaaaagcag caaatttttt aaaactcggt aatccatata atgaagataa attatctctt
    12301 agtgaagaac atgatactat tttagtagtt ttaccattag aaaaaggata tgaatggaat
    12361 tgtcttgaga tagaagtact atccgctgct caatctctag caaatatcta ttgcaacaaa
    12421 gttcgcctca tagatggtca tgtttggaag gaataaaaga aaaagcatag ttggtaattt
    12481 ttagttacgt agggtgggct tcagcccacc gttttttcat ttttgattgt tgattggtgg
    12541 gctaaagccc accctacggt tactaaaatc ccgtcattac ctcgcaggcg ggaatccggt
    12601 ttgttcggtt tcggtttttt agggacagtg ccgcaacatt aaatttccag attcccactt
    12661 tcgcacaaat aacagcgcaa atagggcaaa gataaggata tgggtttttt tctttgaatt
    12721 tactatacaa ttcgcccgtc cccgttatag aaacccaagc cgatgaaaac cctgctccaa
    12781 ctccaaaccg ccgcacaaaa cttcgccgcc tactacaaag accaaaccga cgaacgccgc
    12841 gagaaagaca ccttctggaa cgaatttttc gccattttcg gcatcgaccg caaaaacgtc
    12901 gcccacttcg aataccccgt caaagaccct gccgacaaca cccaattcgt cgatatattt
    12961 tgggagggca tcttccttgc cgaacacaaa tccgccaaca aaaacctgac caaggccaaa
    13021 gagcaggcgg agcgttattt gcaggaaatc gggcgcacca agccctctgc gctgcccgaa
    13081 tattacgccg tcagcgattt tgcccatttc cacctttatc gccgcgtacc tgaagaaggc
    13141 gtggaaaacc aatggcagtt ccctttggaa gcattgcccg aatacatcac gcgcggcgtt
    13201 ttcgacttca tgttcggcat cgaagccaaa gtccgccaaa ttcaagaaga agccgatatt
    13261 caagcggcgg cggccatcgg caggctgcac gacgcgctca aagaagaagg catttacgaa
    13321 gaacacgagc tgcgcctctt catcacgcgc ctacttttcc tcttttttgc cgacgacagc
    13381 gccgttttcc agcgcaacta tctctttcaa gactttttag aaagctgcaa agaaaccgac
    13441 acgctcggcg acaagctcaa ccaactcttt gaattcctca acacacccga ccaaaagcgc
    13501 agcaagaccc aaagcgaaaa atttaaaggt ttcgaatacg tcaacggcgg cctgtttaaa
    13561 gaacgcctgc gcaccttcga cttcaccgcc aagcagcacc gcgccttaat cgactgcggc
    13621 aatttcgact ggcgcaac
//
LOCUS       DAXIDM010000047        13465 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000047 DAXIDM010000000
VERSION     DAXIDM010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 13465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13465
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.047"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(148..483)
                     /locus_tag="ACFOAE_001173"
     CDS             complement(148..483)
                     /locus_tag="ACFOAE_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFC6884663.1"
                     /translation="MFGKAGLGGLMKQAQQMQENMKKAQAKLAETEIEGEAGNGLVKI
                     TMTCAHEVRKIDISPDLIQEAADDKEMLEDLILAALKSARDKAEETANKTMGAFTQGL
                     PPGVGDFFR"
     gene            complement(563..2683)
                     /gene="dnaX"
                     /locus_tag="ACFOAE_001174"
     CDS             complement(563..2683)
                     /gene="dnaX"
                     /locus_tag="ACFOAE_001174"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFC6884664.1"
                     /translation="MAYQVLARKWRPKTFSDLVGQEHVVKALQNALDEGRLHHAYLLT
                     GTRGVGKTTIARILAKSLNCENAQHGEPCGVCESCTQIDAGRYVDLLEIDAASNTGID
                     NIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH
                     KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKITYAPPALQLLGRAAAGSMRDAL
                     SLLDQAIALGSGKVAENDVRQMIGAVDKQYLYELLTGIINQDGAALTAKAQEMAACAV
                     GFDNALGELAILLQHLALIQAVPNALAHDDPDSDILHRLAQTISGEQIQLYYQIAVHG
                     KRDLSLAPDEYAGFMMTLLRMLAFAPLAAASCDANAVIENTELKSPSAQTAEKETAAK
                     KPQPRPEAETAQTSVQTASAAAMPSESKTAEPVSNQENNDVPPWEDAPDEAQAAAGTA
                     QTSAKSIQTASEAETPPENQVSKNKAADNETETSLSEVPSENPIQATPNDEAVETETF
                     AHEAPAEPFYGYGFPDNDCPVEDNAEIPPPDWEHATPADAEEENNADEGSNDENNTPS
                     APPPEFSTENWAAIVRHFARKLGAAQMPAQHSAWTEYHPDTGLMVLAMTAEARATADK
                     KRLDKIRDTLAQAYGLQLTLQTQDWRDEAGRETPAMQDKRVQAEDRQKAQALLEADPA
                     AQKILQAFGAQWQPESLELAANRP"
     misc_feature    complement(1455..1494)
                     /gene="dnaX"
                     /locus_tag="ACFOAE_001174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01843"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="This ribosomal frameshift element is known only in
                     the genus Neisseria; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01843"
     gene            complement(2778..4754)
                     /gene="mutL"
                     /locus_tag="ACFOAE_001175"
     CDS             complement(2778..4754)
                     /gene="mutL"
                     /locus_tag="ACFOAE_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFC6884665.1"
                     /translation="MPRIAALPDHLVNQIAAGEVVERPANALKEIVENSIDAGATAID
                     VELDGGGIRLIRVSDNGSGIHPDDIELALHRHATSKIKTLNDLEHVASMGFRGEGLAS
                     IASVSRLTLTSRQEDSSHATQVKAEDGKLSSPTAAAHPVGTTIEAAELFFNTPARRKF
                     LKSEATEYAHCATMLERLALAHPHIAFSLKRDGKQVFKLPAQSLHERIAAIVGDDFQT
                     ASLEIDSGNGALRLYGAIAKPTFAKGKTDKQYCFVNHRFVRDKVMLHAVKQAYRDVLH
                     NALTPAFVLFLDLPPEAVDVNVHPTKTEIRFRDSRQVHQLVFHTLNKALADTRADLTE
                     SVGNAGEVLHDITGVTPAPMPSENDSENLFNRASDYPTGNKPDTRNAFGASGKTAPMP
                     YQSAYAPQQRSLSLRESRAAMNTYAELYKKTDDIDLELSRFEQARFGNMPSETPAPQT
                     DTPLSDGIPSQSELPPLGFAIAQLLGIYILAQAEDSLLLIDMHAAAERVNYEKMKRQR
                     QENGRLQSQRLLIPVTFAASHEECAALADHADALAGFGLELSDMGGNTLAVRAVPAML
                     GKSDIVSLARDVLGELAQVGSSQTIEEHENRILATMSCHGSIRAGRRLTLPEMNALLR
                     DMENTPRSNQCNHGRPTWVKLTLKELDALFLRGQ"
     gene            4897..5082
                     /locus_tag="ACFOAE_001176"
     CDS             4897..5082
                     /locus_tag="ACFOAE_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3460 family protein"
                     /protein_id="HFC6884666.1"
                     /translation="MYHYQSEATQFLNRLIEEKPELEQQRLENRGLLWDVELNPEEQE
                     NFEAAKVAKKPYTYYQD"
     gene            5093..5761
                     /locus_tag="ACFOAE_001177"
     CDS             5093..5761
                     /locus_tag="ACFOAE_001177"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC6884667.1"
                     /translation="MTTHLSNVAPDLQNYLNAIGEPEHPVLTRLREKTGHHRMGKMAI
                     AREQAAVLVWLAKLIRAEKYLEIGVFTGYSSTALALALPEHGRITACDINVTFTDTAR
                     QVWNEAGVAHKISLHLQPALLTLDDLIAQGEAGSYDLALIDADKPPTPQYFERCLKLV
                     RQGGIIAIDNILLNGRVMREAASDAPPSVGILKDFNQNLPNDTRIVPITLPVGDGLTL
                     LLKK"
     gene            5761..6477
                     /locus_tag="ACFOAE_001178"
     CDS             5761..6477
                     /locus_tag="ACFOAE_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system YbgF family protein"
                     /protein_id="HFC6884668.1"
                     /translation="MKTKLPLFIIWLSVSAACSSPVSRNIQDMRPEPQAEAGSSDAIP
                     YPVPTLQDRLDYLEGTLVRLSNEVETLNGKVKALEHAKTHPSSRAYVQKLDDRKLKEH
                     YLNTEGGSASAHTVETAQNLYNQALKHYKSGRFSAAASLLKGADGGDGGSIAQRSMYL
                     LLQSRARMGNCESVIEIGGRYANRFKDSPTAPEAMFKIGECQYRLQQKDIARATWRSL
                     IQAYPSSPAAKRAAAAVRKR"
     gene            6525..7010
                     /gene="purE"
                     /locus_tag="ACFOAE_001179"
     CDS             6525..7010
                     /gene="purE"
                     /locus_tag="ACFOAE_001179"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFC6884669.1"
                     /translation="MIQIGIIMGSNSDWPVMRQAAQFLEEFGVEYEARVVSAHRTPDL
                     MFQYAETARARGIKAIIAGAGGAAHLPGMVAAKTTVPVLGVPVPSKYLRGEDSLLSIV
                     QMPKGVPVATFAIGEAGAANAALFAVSMLANETPELAQKLADFRAKQEQAVLSMELEQ
                     I"
     gene            complement(7193..8647)
                     /locus_tag="ACFOAE_001180"
     CDS             complement(7193..8647)
                     /locus_tag="ACFOAE_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LutB/LldF family L-lactate oxidation iron-sulfur
                     protein"
                     /protein_id="HFC6884670.1"
                     /translation="MTTQTIKFHMKPETFKQNAAISLQDKPLRKSLRTAMDMLMTKRK
                     AVLTDEEELQSLRDLCEHVRQRSLSKLPALLEQLEENLTKLGVKVHWAETPTEACQII
                     HDIITAKNGKLMVKGKSMVSEEIELNHYLEAKGIKAVESDLGEFIVQMAGEKPTHIVM
                     PAIHKTKEQVSELFHQNLGTPLTDDVDQLTGFARKALRDIYSTADVGLSGVNFAVAET
                     GTLCLVENEGNGRLSTTVPPVHIAITGIEKVVAKLSDIPPLYSLLPRSAIGQNITTYF
                     NMITGPRRSEELDGPQEMHLVLLDNGRSQAYAEDQMRRTLQCIRCGACMNHCPVYTRI
                     GGAAYGTTYPGPIGEIISPHLLGLDATRDLPTACTMCGACVEVCPVRIPITEQMQRLR
                     VEAQRSPTETVPHPIRGQGASHTFGEQMAWRTFNGIFSGSKTYRAFGWAATKFRNLTP
                     RKQLGWTQNRVPMKPAKKTLHELMAEKMRQKEQA"
     gene            complement(8644..9345)
                     /locus_tag="ACFOAE_001181"
     CDS             complement(8644..9345)
                     /locus_tag="ACFOAE_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HFC6884671.1"
                     /translation="MSARENILAKLKKADALPMEEPAVFDYYREKGVSWDSEAERLKH
                     WAAAMRAVKTEIYWVTKSNWMQVFREAAEGKGLKNILLPLATEHGQIARAALAGSNIE
                     PIVFEREIDTWKTEFFTNINAGFSGAQCGIARTGTLMLFSSPEEPRTLSLVPPVHFCL
                     FDTSKMYNEFHNAVEGEKLVENGMPTNVFLISGPSKTADIQLTLAYGAHGPRDLVILA
                     ILPDHISPADLEENA"
     gene            complement(9342..10121)
                     /locus_tag="ACFOAE_001182"
     CDS             complement(9342..10121)
                     /locus_tag="ACFOAE_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HFC6884672.1"
                     /translation="MSATIPPKIIRYDSNPTDVYFFGTCVLDLFMPEAGMDAIALIEQ
                     QGIRVHFPMAQSCCGQPAYSSGHPTEAFDVARAQLDLFPEEWPIVVPSGSCGGMMKHH
                     WPTLFKGSEYEERAVDCAGRIIEFTHFLLAIGFKPEDKGEPLKVAVHTSCAARREMNV
                     HLSGWQLIDGMENVERIVHDHESECCGFGGTFSVKQADISGAMVTDKVAALKETGATE
                     IISADCGCMMNIGGKIAKDEPDMPRPKHIASFLLERTGGKA"
     gene            10405..11811
                     /locus_tag="ACFOAE_001183"
     CDS             10405..11811
                     /locus_tag="ACFOAE_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC6884673.1"
                     /translation="MEKNTLSARAPSPWLPLLLAIAIFMQMLDATILNTALPEIATDL
                     DESPLDMQLAVVAYTLTVALLIPLSGYLADRFGTKKVFFGSIAVFMLGSALCAASGSL
                     FELTLSRVVQGIGGSMLVPIPRLTILRVYDKSKLLNAINYAVMPALIGPVLGPLAGGY
                     LVEYASWHWIFLLNLPIGLLGFILGRNIMPDVKGNDTALDFKGYLIFSAAACLLLLSA
                     ESLSHALPPYFALLPLCGGLLFARRYFRHMKTASKPIYSADLFLIRTFRLGLAGNLFS
                     RLGISSIPFLMPLMFQVAFGFGASLSGWLVAPVALSSLLVKPLIAPLMKRFGYRMVLL
                     WNTKLLAAFIMLLALPDGNSPLWIWIFLSLAIGACNSLQFSAMNTLTLADLRPQQTGS
                     GNSLMAVNQQLAISMGIVVGALILKNWTFLIPASSGLHSAFRMTLLSIGGITLASSLV
                     FKRLHVSDGANLTRNTLS"
     gene            11923..13449
                     /locus_tag="ACFOAE_001184"
     CDS             11923..13449
                     /locus_tag="ACFOAE_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003765285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HFC6884674.1"
                     /translation="MKTRSLISLLCLLLCSCSSWLPPLEERTESRHFNTSKPVRLDNI
                     LQIRHTPHTNGLSDIYLLNDPHEAFAARAALIESAEHSLDLQYYIWRNDISGRLLFNL
                     VYLAAERGVRVRLLLDDNNTRGLDDLLLALDSHPNIEVRLFNPFVFRKWRALGYLTDF
                     PRLNRRMHNKSFTADNRATILGGRNIGDEYFKVGEDTVFADLDILATGSVVGEVSHDF
                     DRYWASHSAHNATRIIRSGNIGKGLQALGYNDETSRHALLRYRETVEQSPLYQKIQTG
                     RIDWQSVQTRLISDDPAKGLDRDRRKPPIAGRLQDALKQPEKSVYLVSPYFVPTKSGT
                     DALAKLVQDGIDVTVLTNSLQATDVAAVHSGYVKYRKPLLKAGIKLYELQPNHAVPAT
                     KDKGLTGSSVTSLHAKTFIVDGKRIFIGSFNLDPRSARLNTEMGVVIESPKIAEQMER
                     TLADTTPEYAYRVTLDRHNRLQWHDPATRKTYPNEPEAKLWKRIAAKILSLLPIESLL
                     "
BASE COUNT         2706 a         3649 c         3803 g         3307 t
ORIGIN      
        1 accgttcacg ccgaatcctg caaactgatg ccgtcattcc cgcgaaggcg ggaatctaga
       61 cccgtcggca cggaaattta tcgagtaaaa cggtttctta gattctacgt tctagattcc
      121 cgcctgcgtg ggaatgacgg tcgggtatca gcggaagaag tcgcccactc cggggggtag
      181 accttgcgtg aatgcgccca ttgttttgtt tgcggtttct tcggctttgt cacgggcgga
      241 tttgagggcg gcgaggatga ggtcttcgag catttctttg tcgtcggcgg cttcttgaat
      301 caaatcgggg ctgatgtcga ttttgcgtac ttcgtgcgcg caggtcattg tgattttgac
      361 caagccgttg cctgcttcgc cttcgatttc ggtttcggca agtttggctt gcgctttttt
      421 catattttcc tgcatttgct gcgcctgttt catcaggccg cctaatccgg cttttccgaa
      481 catactgaat actcctgtct gttttgattg aataagggaa acggcaatgc cgtccgaagg
      541 gttcgggcgg cattatatct gtttatggcc ggtttgccgc caattccagt gattcgggct
      601 gccattgcgc gccgaatgct tggaggattt tttgtgcggc ggggtcggct tcgagcaatg
      661 cttgtgcttt ttgcctgtct tcggcttgga cgcgcttgtc ctgcatcgcg ggggtttccc
      721 ggccggcttc gtcacgccag tcttgggttt gcagggtgag ttgcagcccg taggcttggg
      781 caagggtgtc gcggattttg tcgaggcgtt ttttgtcggc ggtggcgcgg gcttcggcgg
      841 tcatcgccaa aaccatcagg ccggtgtcgg gatggtattc cgtccacgcg gagtgttgcg
      901 ccggcatttg cgccgcgccg agtttgcggg cgaaatgccg gacgatggct gcccagtttt
      961 cggtggaaaa ttcgggcggc ggggcggacg gcgtgttgtt ttcgtcgttg ctgccttcgt
     1021 cggcgttgtt ttcttcttcc gcatcggcag gggtggcgtg ttcccaatcg ggcggcggga
     1081 tttccgcgtt gtcttctacg gggcagtcat tatccggaaa gccgtaaccg tagaaaggtt
     1141 ctgcaggggc ttcgtgtgca aatgtttccg tttcaacggc ttcatcattc ggtgttgcct
     1201 gaatggggtt ttcagacggc acttcggaca aggaagtctc ggtttcgttg tcggctgcct
     1261 tgttcttgga aacttggttt tcgggcggcg tttcggcttc ggatgccgtc tgaatgcttt
     1321 ttgccgacgt ttgcgccgtg ccggctgcgg cttgggcttc gtccggcgcg tcttcccaag
     1381 gcggaacatc gttgttttct tgattggaaa cgggttcggc agttttgctt tcagacggca
     1441 ttgccgctgc ggatgccgtc tgaacggatg tttgggcggt ttccgcttca gggcgcggtt
     1501 ggggcttttt tgcggcggtt tccttttcgg cggtttgtgc cgatggggat tttagttcgg
     1561 tattttcaat cacggcattt gcatcacacg atgctgctgc caagggcgca aacgccagca
     1621 tacgcagcag ggtcatcata aagccggcgt attcgtcggg ggcgaggctc aggtcgcgtt
     1681 tgccgtggac ggcgatttgg tagtaaagct ggatttgttc gccgcttatg gtttgggcga
     1741 ggcggtgcaa aatatcggaa tcggggtcgt cgtgcgccaa ggcattcggc actgcctgta
     1801 tcagggcgag gtgttgcagc agtatggcaa gttcgcccaa ggcgttgtca aagccgacgg
     1861 cacacgccgc catttcctgc gctttggcgg tcagggctgc gccgtcttgg ttgatgatgc
     1921 ctgtcagcag ttcgtaaagg tattgtttgt caaccgcgcc gatcatttgg cggacatcgt
     1981 tttcggcaac tttgcccgaa cccagggcga tggcttggtc gagcaggctc aaggcatcgc
     2041 gcatcgatcc ggcggcggcg cgtcccaaaa gttgcagggc ggggggggcg taggtgattt
     2101 tttcgctgtc gaggacgtgg gcgaggtggt cggcaacctg ctgcgcggtc atattgcgta
     2161 agacgaattg caggcagcgg cttaatacgg taacggggac tttgtgcgga tcggtcgtgg
     2221 caaggatgaa tttgacgtgt tcgggcggct cttccagcgt tttgagcata gcgttgaacg
     2281 cgcttttgga aagcatatgc acttcgtcga tgatatagac tttgtatttg ccggcagtcg
     2341 gtgcatattg ggcgttttcc aatacttcgc ggatgttgtc gatgcctgtg ttggaggcgg
     2401 cgtcgatttc cagcaggtcg acgtagcgtc cggcatcgat ctgcgtacag ctttcgcata
     2461 cgccgcaagg ttcgccgtgt tgcgcgtttt cgcagttgag gcttttggca aggatgcggg
     2521 caatggtggt tttgcccacg ccgcgcgtac cggtcagcag gtaggcgtgg tgcagcctgc
     2581 cttcgtctag agcgttttgc agggctttga cgacgtgttc ctgaccgact aagtcggaaa
     2641 aggttttggg ccgccatttt cgggcgagaa cttgataggc catatttttc tcttggtttc
     2701 ggtcgtgatg tttctgtcgg tgcgtcggaa tgccgtctga acggcggctt cgggcggcgt
     2761 attctagcac tttcggctta ctgtccgcgc aagaacagtg cgtccaattc tttcaaagtc
     2821 agtttgaccc aagtcggcct gccgtggttg cactggttgc tgcgcggcgt attttccata
     2881 tcgcgcagaa gggcgttcat ttcgggcagg gtgagccggc ggccggcgcg gatcgagccg
     2941 tggcaggaca tagtggcgag gatgcggttt tcgtgttctt cgatggtttg gctgctgccg
     3001 acttgggcga gttcgcccaa tacgtcgcgg gcgagcgaga cgatgtcgga tttgcccaac
     3061 attgcgggaa cggcgcggac ggcgagggtg ttgccgccca tatcggacaa ttccaagccg
     3121 aagcctgcca gtgcatcagc atggtcggca agggcggcgc attcttcgtg ggacgcggca
     3181 aaggttacgg gaataagcag gcgttggctt tgcagcctgc cgttttcctg acgttggcgt
     3241 ttcatttttt cgtagttgac gcgttcggcg gcggcgtgca tatcgatgag cagcaggctg
     3301 tcttcggctt gggcaagaat gtagatgcct aatagttggg caatggcaaa accgagcggc
     3361 ggcagttcgg attgggacgg gatgccgtct gaaagcggcg tatctgtttg gggagcaggc
     3421 gtttcagacg gcatattgcc gaaacgtgcc tgctcgaatc ggcttaactc aaggtcgatg
     3481 tcgtcggttt ttttgtagag ttcggcatag gtgttcattg ccgcgcggct ttcgcgcagg
     3541 gacaggctgc gttgttgcgg cgcatatgcg gactgatagg gcataggcgc ggttttgcct
     3601 gatgcaccaa aggcattgcg cgtatcgggt ttgttgcctg tcgggtagtc ggatgcgcga
     3661 ttaaacagat tttcgctgtc gttttcagac ggcattggtg caggcgtaac gccggtaatg
     3721 tcatgcagca cttcgcctgc gttgccgacg ctttcggtca ggtcggcacg cgtgtcggca
     3781 agggctttgt tgagcgtatg gaacacgagt tggtgcacct gccggctgtc gcggaagcgg
     3841 atttctgttt tggtcgggtg gacgttgaca tctacggctt cgggcggcag gtcgaggaaa
     3901 aggacgaaag cgggtgtcag cgcgttgtgc aatacgtcgc ggtatgcctg cttgacggcg
     3961 tggagcatca ctttgtcgcg gacaaaacga tggttgacga agcagtattg tttgtcggtt
     4021 ttgcctttgg cgaaagtcgg cttggcaatc gcgccataga gccgcaatgc gccattgccg
     4081 ctgtcgattt ccaatgatgc cgtctgaaaa tcatcgccga caatggcggc aatccgttca
     4141 tgcaggcttt gtgcagggag tttgaacact tgtttgccgt cgcgtttgag tgagaaggca
     4201 atgtgcggat gcgccagtgc gaggcgttcg agcatagtgg cgcagtgggc gtattcggtg
     4261 gcttcagact tgaggaactt gcgccgcgcc ggtgtattga agaagagttc ggcagcttcg
     4321 atggtcgtgc cgacggggtg ggcggcggcg gtggggctgc tgagtttgcc gtcttcggct
     4381 ttgacttggg ttgcgtgcga actgtcttct tgacggctgg tcagggtcag gcggctgacg
     4441 gaggcgatgc ttgccaagcc ttcgccgcga aagcccatgc tggcgacgtg ttccaagtca
     4501 tttaaggttt tgattttgct ggtggcgtgg cggtggagcg cgagttcgat gtcgtccgga
     4561 tggataccgc tgccgttgtc gctgacgcga atcaggcgga tgccgccgcc gtccagctcg
     4621 acatcaatcg ccgttgcgcc tgcatcgata ctgttttcaa cgatttcttt caaggcgttg
     4681 gcagggcgtt cgactacttc gccggcggcg atttggttga cgagatggtc gggcagggcg
     4741 gcaatgcgtg gcataaggta ggcttccgtt gcaaaaacgc tttattctat aataaaaccc
     4801 cttatctttc tgcctgtatt cttgataaaa gccgtttatc ccgtttggaa aataccagta
     4861 taatcacgcc gtatcccgta aaattggagc gcaaagatgt atcactacca atccgaagcc
     4921 acacaattcc tcaaccgcct gattgaagaa aaacctgagt tggaacagca gcgtttggaa
     4981 aaccgggggc ttttgtggga tgtcgaactc aatcccgaag aacaggaaaa cttcgaggcg
     5041 gcaaaagtag cgaaaaaacc ttatacctat taccaagact gaacccgccg aaatgacgac
     5101 ccatctgtcc aatgttgcac cggacctgca aaactatttg aacgccatcg gcgaacccga
     5161 acatcccgtt ttgacgcggc tgcgtgagaa gaccgggcat caccgtatgg gcaaaatggc
     5221 gattgcgcgc gaacaggcgg cggttttggt ttggctggca aagctgatcc gtgcggaaaa
     5281 atatctggaa atcggcgtat ttaccggata cagcagcacc gcgcttgcat tggcgttgcc
     5341 cgaacacggg cggattaccg cctgcgacat caatgtaacc tttaccgata cggcgcgtca
     5401 ggtttggaac gaggccggtg tggcacataa aatcagcctg cacctgcaac ccgcattgct
     5461 gacattggat gatttgattg cacagggtga agccggaagc tacgatttgg cactgataga
     5521 cgcagacaaa ccgcccacgc cgcaatattt cgagcgttgc ctcaagcttg tccggcaagg
     5581 cggcatcatc gccatcgaca atattttgct gaacggaagg gtgatgcgcg aagcggcttc
     5641 cgatgcgccg cccagcgtcg gcatcctcaa agatttcaat caaaacctgc cgaacgatac
     5701 gcggattgtc cccatcaccc tgcccgtcgg cgacggcttg accctgcttc tgaaaaaata
     5761 atgaagacca aattaccgct ttttatcatt tggctgtccg tatctgccgc ctgttcttcc
     5821 cctgtttccc gcaatattca ggatatgcgg cccgaaccgc aggcagaggc aggtagttcg
     5881 gacgctattc cctatcccgt tcccactctg caagaccgtt tggattatct ggaaggcaca
     5941 ctcgtccgcc tgtcgaacga agtggaaacc ttaaacggca aagtcaaagc actggagcat
     6001 gcgaaaacac acccttccag cagggcatac gtccaaaaac tcgacgaccg caagttgaaa
     6061 gagcattacc tcaataccga aggcggcagc gcatccgcac ataccgtcga aaccgcacaa
     6121 aacctctaca atcaggcact caaacactat aaaagcggca ggttttctgc cgctgcctcc
     6181 ctgttgaaag gcgcggacgg aggcgacggc ggcagcatcg cgcaacgcag tatgtatctg
     6241 ttgctgcaaa gcagggcgcg tatgggcaac tgcgaatccg tcatcgaaat cggagggcgt
     6301 tacgccaacc gtttcaaaga cagcccaacc gcgcccgaag ccatgttcaa aatcggcgaa
     6361 tgccaataca ggttgcagca gaaagacatt gcaagggcga cttggcgcag cctgatacag
     6421 gcttacccga gcagcccggc ggcaaaacgc gccgccgcag ccgtgcgcaa acgatagttt
     6481 ttccattttt ccgcttttta ccccatccgc accaaggagg atttatgata caaatcggca
     6541 tcatcatggg cagcaacagc gattggcccg ttatgcggca ggcagcgcag tttcttgaag
     6601 agttcggcgt agaatatgag gcgcgcgttg tttccgcaca ccgcaccccg gatttgatgt
     6661 tccaatacgc cgaaaccgca cgggcgcgcg gcatcaaagc catcatcgcg ggtgcgggcg
     6721 gcgcggcgca tttacccggt atggttgccg ccaagaccac cgtccccgtt ttgggcgtac
     6781 ccgtccccag caaatacctg cgcggcgaag attcgctttt atcgattgta caaatgccca
     6841 aaggcgtacc cgtcgccaca ttcgccatcg gcgaggcagg cgcggcaaat gccgcattgt
     6901 tcgccgtttc catgctcgcc aacgaaaccc ccgaactggc gcaaaaactg gcagacttcc
     6961 gagccaaaca ggaacaggct gttttgagta tggaattgga acagatttaa aacccgccgt
     7021 ccgcgaatat atagtggctt aaatttaaac cagtacggcg ttccctcgcc ttgccgtact
     7081 atttgtactg tctgcggctt cgtcgccttg tcctgatttt tgttaatcca ctatacaaat
     7141 gccgtctgaa gccctgtttc gggtttcaga cggcattttt gcgaacaact ttttatgcct
     7201 gttctttttg gcgcattttt tctgccatta gttcgtgcag ggttttcttc gccggtttca
     7261 tcggcacgcg gttttgcgtc caacccaact gtttgcgcgg ggtcaggttg cggaacttgg
     7321 tggctgccca accgaaggcg cggtaggttt tgctgccgct gaaaataccg ttgaatgtgc
     7381 gccacgccat ttgttcgccg aaggtatgcg atgcgccttg ccctcggatg gggtgcggca
     7441 cggtttcggt cggcgaacgt tgcgcttcaa cgcgcaaacg ctgcatttgt tcggtaatcg
     7501 ggatgcgtac cggacagact tccacacacg caccgcacat ggtacaggcg gtcggcaggt
     7561 cgcgggtggc atccagaccc aacaggtgag gggaaataat ctcgccaatc gggccgggat
     7621 aggttgtgcc gtatgccgcg ccgccgatgc gggtataaac cgggcaatgg ttcatacacg
     7681 cgccgcaacg gatacattgc agggtgcggc gcatttggtc ttcggcataa gcctggctgc
     7741 ggccgttgtc gagcagaacc aagtgcattt cttgcggacc gtctaattct tcactgcggc
     7801 gcgggccggt aatcatattg aaataggttg tgatgttctg accgatggcg gagcgcggca
     7861 gcagactgta caagggtggg atgtcggaca atttcgccac cactttttca atgccggtaa
     7921 tagcgatatg cacgggcgga acggtggtac tcaagcgacc gttgccctcg ttttccacca
     7981 gacacagcgt acctgtttca gcaacggcaa agtttacgcc actcaagccg acatcggcag
     8041 tgctgtaaat atcgcgcagg gctttgcggg cgaagccggt cagttggtcc acatcgtctg
     8101 taagcggtgt gccgaggttt tggtggaaca gttcgctcac ctgttctttg gttttatgga
     8161 ttgcaggcat cacgatatgg gtcggttttt cgcctgccat ttggacgatg aactcgccca
     8221 agtcgctttc taccgcttta atgccttttg cttcaagata atggttcagc tcgatttcct
     8281 cgctgaccat cgatttgcct ttgaccatca gcttgccgtt tttggctgtg atgatgtcgt
     8341 ggataatttg gcaggcttcg gtcggggttt ctgcccagtg cactttcacg cccaacttag
     8401 tcaggttttc ttccagctgc tccagcaggg caggtaattt agacaatgaa cgctgacgga
     8461 cgtgttcgca caaatcgcgc aagctttgca gctcttcttc gtcggtcaaa acggctttgc
     8521 gtttggtcat cagcatatcc atcgcggtac gcaggctttt gcgcaaaggc ttgtcttgaa
     8581 gggaaattgc ggcgttttgc ttgaaagttt ccggcttcat gtggaacttg atggtttgcg
     8641 tagtcatgcg ttttcctcca aatcggcagg ggaaatgtgg tcgggcagga tggcgaggat
     8701 gaccaaatcg cgcgggccgt gcgcgccgta agcaagcgtc agttggatgt ctgcggtttt
     8761 ggacgggccg gaaatcagga atacattggt cggcataccg ttttccacca gtttttcgcc
     8821 ttcgacggca ttatgaaact cgttgtacat cttggacgta tcgaacaggc agaaatgcac
     8881 gggcggaacg agactcaaag tacgcggttc ttcggggctg gaaaacagca tcagcgtgcc
     8941 ggtgcgggcg atgccgcatt gcgcgccgct gaagcccgca ttgatgttcg tgaaaaactc
     9001 ggttttccaa gtatcgattt cgcgctcgaa gacaatcggt tcgatattgc tgcccgccaa
     9061 tgcggcacgg gcaatttgtc cgtgttcggt cgccaagggc agcaggatgt ttttcaaacc
     9121 cttgccttct gccgcttcgc ggaaaacctg catccaattg cttttcgtca cccaataaat
     9181 ttcggttttg accgcgcgca ttgcggcagc ccaatgtttc agacgctcgg cttcgctgtc
     9241 ccaagaaacg cccttttcgc ggtaataatc gaaaaccgca ggctcttcca tcggcaaggc
     9301 atcggctttt ttcagttttg ccaaaatatt ttcacgcgcg ctcatgcttt gcctccggtg
     9361 cgttccaaca agaaggatgc gatatgtttc ggacgcggca tatccggctc gtccttggcg
     9421 attttgccgc cgatgttcat catacagccg cagtccgcgc tgatgatttc ggttgcgccg
     9481 gtttctttca gcgcggcgac tttgtcggtt accatcgcgc cggaaatatc ggcttgtttg
     9541 acggagaatg tgccgccgaa gccgcaacat tcgctttcgt ggtcgtggac gatgcgttcg
     9601 acgttttcca taccgtcaat cagttgccag cctgaaagat ggacattcat ttcgcggcgg
     9661 gcggcgcagg aagtgtgaac ggcgactttg agcggttcgc ccttgtcttc gggtttgaaa
     9721 ccgatggcaa gcaggaaatg ggtaaactcg atgatgcggc cggcgcaatc cacagccctt
     9781 tcctcgtact cgctgccttt aaacagcgtc ggccaatggt gtttcatcat accgccgcac
     9841 gaaccggacg gtacgacaat cggccactcc tcggggaaaa ggtcgagttg cgctctggcg
     9901 acatcaaagg cttcggtcgg atggccggat gaataggcgg gctggccgca gcagctttgc
     9961 gccatcggga aatggacgcg tatgccctgt tgctcgatta gggcaatggc atccatgcct
    10021 gcttcgggca taaaaagatc aaggacgcaa gtgccgaaaa aatagacatc ggtcggattg
    10081 ctgtcgtatc ggatgatttt tgggggaatg gttgcgctca tgttttttga taacgggaaa
    10141 cccgtttttt tctgtagaaa ggtaagcgtt tactttaagt aattgactgt tgcgggtcaa
    10201 gtctaatttt aaaaaataat ccggttttcc ttacaaacta ccccataacg cttactgtac
    10261 cttaatctga tggttttcga taataattat cattacaatg caataccggt tcgtttgctt
    10321 gtgaacattc aagatgccga ctctgacggc attcagacag cgtctgaaaa caataacggc
    10381 acaaggatgg ggtacaatcg ccctatggaa aaaaacaccc tatccgcccg cgcaccatcc
    10441 ccttggctgc cgcttctgct ggcaattgcc atttttatgc agatgttgga tgcgaccatt
    10501 ttaaataccg cactgcctga aattgccacc gacctggacg aatcgcctct ggatatgcaa
    10561 ctggcagtcg ttgcctatac gctgacggtt gccctgctga ttcctttgag cggttatttg
    10621 gcggacaggt tcggaacgaa aaaagtcttt ttcggttcga ttgccgtttt tatgctcgga
    10681 tcggcattgt gcgccgcatc gggttcgctg tttgaattga cgctttcccg tgtcgttcag
    10741 ggcatcggcg gttcgatgct ggttccgata ccgcgtctga ccatcttgcg tgtgtacgac
    10801 aagtccaagc tgctcaacgc catcaattat gcggttatgc ccgcattaat cggaccggtt
    10861 ttagggcctt tggcgggcgg ttatctggtc gaatacgctt cgtggcactg gattttcctg
    10921 ctcaacctgc ccatcggtct tctgggtttc atattgggac gcaacatcat gcccgatgtc
    10981 aaaggcaacg ataccgctct ggatttcaaa ggctatctga ttttttctgc cgccgcgtgc
    11041 ctcttgttac tttcggcaga aagcctgtcg cacgcgctgc ctccgtattt tgcactgttg
    11101 ccgctgtgcg gcggactgct gtttgcacgc cgttatttcc gacatatgaa aactgcgtcc
    11161 aaaccgattt attccgccga cctgtttctg atacgcactt tccgtctggg actggcgggc
    11221 aatctgttca gccgtctcgg catcagctcg attccttttc tgatgcccct gatgtttcaa
    11281 gtcgctttcg gcttcggcgc aagcctgtcg ggttggctgg tcgcccccgt cgccctgtct
    11341 tcgctgctgg tcaaaccgct gattgcaccg ctcatgaaac gtttcggcta ccgcatggta
    11401 ctgctttgga acaccaagct gcttgccgcc ttcatcatgc tgctcgccct gcctgatgga
    11461 aactcgccgc tgtggatttg gattttcctc tcgctggcga tcggcgcgtg caactcccta
    11521 cagttttctg ccatgaacac actgaccctc gccgatttgc gcccgcaaca gaccggcagc
    11581 ggcaacagcc tgatggcggt caaccaacag cttgccatca gcatgggcat tgttgtcggc
    11641 gcattaatcc ttaaaaactg gacatttctg ataccggctt cttcaggtct gcattccgcc
    11701 ttccgtatga ccctgctcag catcggcggc atcacccttg cctcgtcgtt ggttttcaag
    11761 cgtctgcacg tttcagacgg cgcaaacctg acacggaaca cactgtccta aagcggtccg
    11821 cacgcaaaac ttttacccgt ttcaacgttt ggattatgat tccgcacatc catgcgcgcc
    11881 aaccccaaaa cacaggcaat gccgtctgaa accatatccc tgatgaaaac acgcagccta
    11941 atttcccttt tatgcctcct tctctgttca tgttcttcat ggttgccccc actggaagaa
    12001 cggacggaaa gccgtcattt caatacttcc aaacccgtcc gcctggacaa catcctgcaa
    12061 atccggcaca cccctcatac caacgggcta tccgatatct atctgctgaa cgacccccac
    12121 gaagcctttg ccgcccgcgc cgcccttatc gaatctgccg aacacagcct cgatttgcaa
    12181 tactacatct ggcgcaacga catttccggc cgactgctgt tcaacctcgt gtaccttgcc
    12241 gcagaacgcg gtgtgcgcgt acgcctgctg ttggacgaca acaacacgcg cggattggac
    12301 gacctcctgc tcgccctcga cagccatccc aatatcgaag tgcgcctgtt caaccccttc
    12361 gtcttccgca aatggcgcgc actcggctac ctgactgact tcccccgcct caaccgccgc
    12421 atgcacaaca aatcctttac cgccgacaac cgcgccacca tactcggcgg acgcaatatc
    12481 ggcgacgaat acttcaaagt cggtgaggac accgttttcg ccgacctgga tatcctcgct
    12541 accggcagcg tcgtcggcga agtatcgcac gacttcgacc gctactgggc aagccattcc
    12601 gcccacaacg ccacgcgcat catccgcagc ggcaacatcg gcaagggtct tcaagcactc
    12661 ggatacaacg acgaaacgtc cagacacgcg ctcctgcgct accgcgaaac cgtcgaacag
    12721 tcgcccctct accaaaaaat acagacagga cgcatcgact ggcagagcgt ccaaacccgc
    12781 ctgatcagcg acgaccctgc aaaaggactc gaccgcgacc gccgcaaacc gccgattgcc
    12841 gggcggctgc aagacgcgct caaacagccc gaaaaaagcg tctatctggt ttcaccctat
    12901 ttcgtcccca caaaatccgg cacagacgca ctggcaaaac tggtgcagga cggcatagac
    12961 gttaccgtcc tgaccaactc gctacaggcg accgacgttg ccgccgtcca ttccggctat
    13021 gtcaaatacc gaaaaccgct gctcaaagcc ggcatcaaac tctacgagct gcaacccaac
    13081 catgccgtcc ctgccacaaa agacaaaggc ctgaccggca gctccgtaac cagcctgcat
    13141 gccaaaacct tcattgtgga cggcaaacgc atcttcatcg gctcattcaa cctcgacccc
    13201 cgttccgcac ggctcaatac tgaaatgggc gttgttatcg aaagccccaa aatcgcagaa
    13261 cagatggagc gcacccttgc cgataccaca cccgaatacg cctaccgcgt taccctcgac
    13321 aggcacaacc gcctgcaatg gcacgatccc gccacccgaa aaacctaccc gaacgaaccc
    13381 gaagccaaac tttggaaacg catcgccgca aaaatcctat ccctgctgcc catagaaagt
    13441 ttattataga aatatagtgg attaa
//
LOCUS       DAXIDM010000048        13235 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000048 DAXIDM010000000
VERSION     DAXIDM010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 13235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13235
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.048"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(175..303)
                     /locus_tag="ACFOAE_001185"
                     /pseudo
     CDS             complement(175..303)
                     /locus_tag="ACFOAE_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242091.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            complement(378..1721)
                     /gene="argG"
                     /locus_tag="ACFOAE_001186"
     CDS             complement(378..1721)
                     /gene="argG"
                     /locus_tag="ACFOAE_001186"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HFC6884675.1"
                     /translation="MNQNHTILQNLPVGQKVGIAFSGGLDTSAALLWMKLKGALPYAY
                     TANLGQPDEDDYNAIPKKAMEYGAENARLIDCRAQLAHEGIAAIQCGAFHVSTGGIAY
                     FNTTPLGRAVTGTMLVSAMKEDDVNIWGDGSTYKGNDIERFYRYGLLTNPALKIYKPW
                     LDQQFIDELGGRHEMSEFLIANGFNYKMSVEKAYSTDSNMLGATHEAKDLEFLNSGIK
                     IVKPIMGVAFWDENVEVSPEEVSVRFEEGVPVALNGKEYADPVELFLEANRIGGRHGL
                     GMSDQIENRIIEAKSRGIYEAPGMALFHIAYERLVTGIHNEDTIEQYRINGLRLGRLL
                     YQGRWFDSQALMLRETAQRWVAKAITGEVTLELRRGNDYSILNTESPNLTYQPERLSM
                     EKVEDAAFTPLDRIGQLTMRNLDITDTRAKLGIYSQSGLLALGEGSVLPQLGNKK"
     gene            1846..2646
                     /locus_tag="ACFOAE_001187"
     CDS             1846..2646
                     /locus_tag="ACFOAE_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFC6884676.1"
                     /translation="MNAFNLIIIGDEILHGSRQDKHFVFFKSLLESKGLKLNQVQYLP
                     DEPDLLVRQLRRSFSDGIPTFVTGGIGATPDDHTRQAAAAALELPVVRHPEAAKFIEG
                     VTLKRGEPLDSPEHAQRLKMADFPEGAELVPNPFNNIAGFSIREHYFFPGFPVMAHPM
                     AEWVLDTYYVGRFNQTKRGSRSVYVFEQPESRITPLMEHIEQTYPGVRSYSLPSVGWT
                     HSDGTQVKPHIEFGIKAEGEAVNLLDAAWAEVLHSLDGLGAELKNRVN"
     gene            2686..3672
                     /locus_tag="ACFOAE_001188"
     CDS             2686..3672
                     /locus_tag="ACFOAE_001188"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HFC6884677.1"
                     /translation="MQYRIRRENEAPEAKNAGETLWERDIMREVLLSAYRDRRRERMW
                     KNIWRAVSTLILVALIAGIFQKDEAALQLAGNTPHTAVVNLYGEIGNGVEDQVKKLKD
                     GMEAAYKNPQAKAIIIRANSPGGSPVVSNTAFEEIRRLKAQHPGIPVYLVAEDMCASG
                     CYYIAAAADKIYADPSSIIGSIGVIGSSFDATGLMEKIGVKRRVKIAGSNKGMGDPFS
                     PETPEQSKIWEEMLTGIHGEFIKAVKTGRGDRLKFRQYPDVFSGRVYTGADALKVGLV
                     DGLGNIYSVARDVVKAPDVVDYTPKDDFGRILGRRFGAELKASVREALQAVR"
     gene            4329..4591
                     /locus_tag="ACFOAE_001189"
                     /pseudo
     CDS             4329..4591
                     /locus_tag="ACFOAE_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021111752.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4629..5003)
                     /locus_tag="ACFOAE_001190"
     CDS             complement(4629..5003)
                     /locus_tag="ACFOAE_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC6884678.1"
                     /translation="MIIQNEFNLYPSNMLPERFCYPEKYVRISNDTSLIPYIQPHNFH
                     WWFENYGTEGAEVAYIFRNSILPDLNLIPFASNGEWEAYFDGNDVTGNSRVIVINLDN
                     IENHEFFNSFEDWLELAIKDTW"
     gene            complement(5000..5128)
                     /locus_tag="ACFOAE_001191"
     CDS             complement(5000..5128)
                     /locus_tag="ACFOAE_001191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884679.1"
                     /translation="MPQTWGEAIQFRIKKQIENELAPPNWSTQFPNGSIYDPKVTK"
     gene            complement(5176..5532)
                     /locus_tag="ACFOAE_001192"
     CDS             complement(5176..5532)
                     /locus_tag="ACFOAE_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMP12 family DNA mimic protein"
                     /protein_id="HFC6884680.1"
                     /translation="MNEHNLLIFCLKDNVSISEYTEMIDWAYKNIQSETVVEITENQI
                     IEYQNRGLWRLVSEITDNWLFGPSEGDWLIDKESILAVKEKLQNSDFSTEPLVKNIIH
                     VLEYAIKNEKTVIFHF"
     gene            complement(5537..5641)
                     /locus_tag="ACFOAE_001193"
     CDS             complement(5537..5641)
                     /locus_tag="ACFOAE_001193"
                     /inference="COORDINATES: protein motif:HMM:NF018014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884681.1"
                     /translation="MDDIRGIIQGAVNPLIYKVSKQKIIYNNKLISGT"
     gene            complement(5675..6019)
                     /locus_tag="ACFOAE_001194"
     CDS             complement(5675..6019)
                     /locus_tag="ACFOAE_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884682.1"
                     /translation="MNLENYENILIKLLFYHNNLVNEYSYFIENKNLFKIVSRTKTSK
                     GFFFTIEKPLNFLSKKTYFEFNFKYLHSGKERFGSFMCWINTNLMEFEGVFFNDLLPD
                     NMIINNFFEIND"
     gene            complement(6178..6579)
                     /locus_tag="ACFOAE_001195"
     CDS             complement(6178..6579)
                     /locus_tag="ACFOAE_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884683.1"
                     /translation="MKLKSLDFPTGYFYFDNAAINSDKVEVIAVGYRNTDKTIKIFIE
                     DVIHFRVVDESYFIDTFMDLISEDADRALLHENGGQSFFELLDECYAEWILKESYFPL
                     NREFFKYYIFMFEQTFIEIIGSSATYSIIEG"
     gene            complement(6583..7035)
                     /locus_tag="ACFOAE_001196"
     CDS             complement(6583..7035)
                     /locus_tag="ACFOAE_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884684.1"
                     /translation="MQTKALGTVDEIGDTVQQVGKQASGQKTSGGNPAIDSDPYSPSS
                     VAARIEAGKARSDLQIKDILSNTTQRSKTKGPAVQYDKVGDYNDALNDFNSLNVRNVQ
                     TRPNGTITGNLPDGRAVNARNDSSGGEPTLEITISNNRKIKIRYGNTR"
     gene            complement(7030..7323)
                     /locus_tag="ACFOAE_001197"
                     /pseudo
     CDS             complement(7030..7323)
                     /locus_tag="ACFOAE_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225727.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            complement(7393..7710)
                     /locus_tag="ACFOAE_001198"
     CDS             complement(7393..7710)
                     /locus_tag="ACFOAE_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884685.1"
                     /translation="MKKNIFHNVSLYEIIFSDNGNTLTLSFTDTIEGNYFGYIKCSNI
                     LNFKLDTNNFVDYEDKEDSLFPLFIPEIELYKYQFYSEIIIDVGIIIKISAETINFEP
                     LGK"
     gene            complement(7707..7967)
                     /locus_tag="ACFOAE_001199"
     CDS             complement(7707..7967)
                     /locus_tag="ACFOAE_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFC6884686.1"
                     /translation="MRPTTRDELRQALQEQGFRRTGSDAAQYETWKGPDGVKIDIRPN
                     GEVIRTQRVPRTDGVQGKYPQRQDYEGNPLPNNHHHSGYFVK"
     gene            complement(7965..8309)
                     /locus_tag="ACFOAE_001200"
                     /pseudo
     CDS             complement(7965..8309)
                     /locus_tag="ACFOAE_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225727.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            complement(8735..9079)
                     /locus_tag="ACFOAE_001201"
     CDS             complement(8735..9079)
                     /locus_tag="ACFOAE_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884687.1"
                     /translation="MIIEHNGNIHKIARMTGNKNNFLEIILSDIHENIKIKPLTIKVK
                     GENVINILPEEVSFYVKQGVDLIYEKYKRKFFISEISFCQSDSRPSSIYAFLTFHLLE
                     DIIKNESPSNYT"
     gene            complement(9117..9461)
                     /locus_tag="ACFOAE_001202"
     CDS             complement(9117..9461)
                     /locus_tag="ACFOAE_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884688.1"
                     /translation="MFLDDVNVFLDDLNVFLDDLNTNPITDEWYMSNFADKHIKILES
                     YEAFDILKQFVDYMIEEYDEKSEYEIMEILRQLKYQADTNEKFYTNTQKQKIVELYKQ
                     EISQDILNEIFR"
     gene            complement(9464..9748)
                     /locus_tag="ACFOAE_001203"
     CDS             complement(9464..9748)
                     /locus_tag="ACFOAE_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884689.1"
                     /translation="MAGGNKSLKIGTQSVEKSTGRTIPNNLKEQLAMEEVKANPQGKT
                     PARIPPMSDTKNGWLAKDGWVKRVQNVNKIEIHYIENSRTGEKTDFKFKD"
     gene            complement(9722..10066)
                     /locus_tag="ACFOAE_001204"
                     /pseudo
     CDS             complement(9722..10066)
                     /locus_tag="ACFOAE_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503511.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            complement(10150..10452)
                     /gene="imm40"
                     /locus_tag="ACFOAE_001205"
     CDS             complement(10150..10452)
                     /gene="imm40"
                     /locus_tag="ACFOAE_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Imm40 family immunity protein"
                     /protein_id="HFC6884690.1"
                     /translation="MLNEIFEIYSRQGESLIGIGIREAALPVPIAIDILNLFINERIL
                     VLGGDIYIKKDNYFYQTYDNWYYEGSNLFNSIDKAMHYLSQIKLENAYVSFVLKFI"
     gene            complement(10478..10744)
                     /locus_tag="ACFOAE_001206"
                     /pseudo
     CDS             complement(10478..10744)
                     /locus_tag="ACFOAE_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224185.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10765..10971)
                     /locus_tag="ACFOAE_001207"
     CDS             complement(10765..10971)
                     /locus_tag="ACFOAE_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPCC family cysteine-rich protein"
                     /protein_id="HFC6884691.1"
                     /translation="MMENSKKTWEIDGEIWLHCPVCGTEVMDYDICDVCQWQNTGETN
                     IDGGPNEMTLAEAKEAYAKGLPIR"
     gene            complement(10937..11377)
                     /locus_tag="ACFOAE_001208"
     CDS             complement(10937..11377)
                     /locus_tag="ACFOAE_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafB"
                     /protein_id="HFC6884692.1"
                     /translation="MAGGNKPPKPSTQQHPTHSDNNIGLPASYVKPDTSISPTGTIQD
                     RIRWTKSKFPTEKSLNGHFKAHGKEFGDITIEDYQKMASDLLSKQTSDKILGYQTEHR
                     RVRYDINNNIYVLANPKTFKIKTMFKPNLGKKYYDGEFKKDMGN"
     gene            complement(11357..11686)
                     /locus_tag="ACFOAE_001209"
                     /pseudo
     CDS             complement(11357..11686)
                     /locus_tag="ACFOAE_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225727.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI.; incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
     gene            complement(11792..12163)
                     /locus_tag="ACFOAE_001210"
     CDS             complement(11792..12163)
                     /locus_tag="ACFOAE_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042546 - cell wall biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMI1/KNR4 family protein"
                     /protein_id="HFC6884693.1"
                     /translation="MIKQNSFVPYPEAMLPKGFKYPQSYLKLAQSTHAINYDEQYSFP
                     WWFENAESNISEVIDIYFEITGIPNLLPFARNQEWAACFDISDKSGNPKIIVVNLDNT
                     KYYETFENFDTWLKEAENDGW"
     gene            complement(12160..12515)
                     /locus_tag="ACFOAE_001211"
                     /pseudo
     CDS             complement(12160..12515)
                     /locus_tag="ACFOAE_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012504007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12543..12749)
                     /locus_tag="ACFOAE_001212"
     CDS             complement(12543..12749)
                     /locus_tag="ACFOAE_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884694.1"
                     /translation="MNILSINNQNSTISLTQDEVFVLRAILNEIYAGVCVDSREFENV
                     SGVRKHEVDNLQQQFAGIYKKMTT"
     gene            complement(12759..>13235)
                     /gene="mafB"
                     /locus_tag="ACFOAE_001213"
     CDS             complement(12759..>13235)
                     /gene="mafB"
                     /locus_tag="ACFOAE_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 3"
                     /protein_id="HFC6884695.1"
                     /translation="ATTVWGGKKVELNPTKWDWVKNTGYKKPAARHMQTVDGEMAGGN
                     RPPKSITSNSKADASTQPSLQAQLIGEQISSGHAYNKHVIRQQEFTDLNINSPADFAR
                     HIENIVSHPTNMKELPRGRTAYWDDKTGTIVIRDKNSDDGGTAFRPTSGKKYYDDL"
BASE COUNT         3592 a         2807 c         2603 g         4233 t
ORIGIN      
        1 ttgcaaaaat agtctgttaa cgaaatttga cgcataaaaa tgcgccaaaa aattttcaat
       61 tgcctaaaac cttcctaata ttgagcaaaa agtaggaaaa atcagaaaag ttttgcattt
      121 tgaaaatgag attgagcata aaattttagt aacctatgtt attgcaaagg tctcgacccg
      181 ccagccttcg ggggtttgtt tgttgaggaa cgcgctgaaa ttgacggggt tgacctttgt
      241 cgcgccgaaa aacaggctgg acaacaggct ttcctgataa atgacgactt tgtattcttt
      301 cataggattc cttttaacat aagggatcat cttttcagac gaccccttaa gttgctaatg
      361 atgcaaaaca gcaaacctta tttcttattg cccaactgcg gcaataccga gccttcgccc
      421 aatgccaata aaccgctttg cgagtagatg cccagtttgg cgcgggtgtc ggtgatgtcg
      481 aggttgcgca tagtcagttg tccgatacgg tcgagcggtg tgaacgctgc gtcttcgact
      541 ttttccatac tcaggcgttc gggttggtag gtcaggttgg gcgattcggt gttcagaatc
      601 gagtagtcgt tgccgcgacg caattcgagg gttacttcgc cggtaatggc tttggcgacc
      661 cagcgttggg cggtttcgcg caacatgagt gcttggctgt cgaaccagcg gccttggtag
      721 agcaggcggc cgaggcgcag gccgttgatg cggtattgtt cgatggtgtc ctcgttgtgg
      781 atgccggtaa ccaagcgttc gtaggcgatg tggaacaatg ccatgcccgg ggcttcgtag
      841 atgccgcgcg atttggcttc gatgatgcgg ttttcgattt ggtcgctcat gcccaagccg
      901 tggcggccgc cgatgcggtt ggcttcgagg aagagttcga cgggatcggc gtattctttg
      961 ccgttcagtg caaccggcac gccttcttca aagcgcacgc tgacttcttc ggggctgact
     1021 tcgacgtttt cgtcccaaaa ggcaacgccc ataatgggtt tgacgatttt gatgcccgag
     1081 ttcaaaaatt ccaagtcttt ggcttcgtgg gtggcaccca acatattgga atcggtggag
     1141 taggcttttt ccaccgacat tttgtagttg aagccgttgg caatcagaaa ttcgctcatt
     1201 tcgtgacggc cgccgagttc gtcgataaat tgctgatcga gccagggttt gtagattttc
     1261 agcgcgggat tggtgagcaa accgtagcgg tagaaacgct cgatgtcgtt gcctttgtag
     1321 gtgctgccgt cgccccaaat attcacatcg tcttctttca tggcggaaac aagcatcgtg
     1381 ccggttacgg cgcgacccag aggcgtggtg ttgaaatagg cgatgccgcc ggtggaaacg
     1441 tggaacgcgc cgcattggat ggcggcgatg ccttcgtgtg ccaactgcgc gcggcagtcg
     1501 atcaggcggg cgttttccgc accgtattcc attgcttttt tgggaatggc attgtagtcg
     1561 tcttcgtcgg gctggccgag gttggcggtg taggcgtaag gcagtgcgcc tttgagtttc
     1621 atccacaaca gcgcggcaga ggtatcaaga ccgccggaga aagcgatgcc gactttttga
     1681 ccgacgggga ggttttgtaa aatagtatgg ttttggttca tgaaaaaatc ctcggtagct
     1741 tgaaaaatca aagccattat cttataaata ggaaatattg tcagccatca tgccgtctga
     1801 acgggtattc cgccgtttca ggcggtattt aaaaccgaaa acattatgaa cgcgttcaac
     1861 ctcatcatca tcggcgacga aatcttacac ggcagccgcc aagacaagca tttcgtcttt
     1921 ttcaaatccc tgctcgaatc caaagggctg aagctcaatc aggtgcaata tctgcccgac
     1981 gaacccgatt tgctggtcag gcaactgcgc cgcagctttt cagacggtat accgacgttt
     2041 gttaccggcg gcatcggtgc tacgcccgac gaccacacgc gccaagcggc cgccgccgct
     2101 ttggagttgc ccgtcgtccg ccatcctgaa gccgccaagt ttatcgaagg cgtaaccctg
     2161 aaacgcggcg agccgctcga ttcgcccgaa cacgcccaac gcctgaaaat ggcagatttc
     2221 cccgaaggcg cggaattggt gcccaatccg tttaacaaca tcgccggatt ttctatccgc
     2281 gagcattatt ttttccccgg cttccccgtg atggcgcacc cgatggcgga atgggttttg
     2341 gatacttatt acgtcggccg cttcaaccaa accaaacgcg gcagccgcag cgtgtatgtg
     2401 tttgagcagc ccgaatcgcg cattacgccg cttatggagc atatcgagca aacttatccc
     2461 ggcgtgcgtt cgtacagcct gcccagcgtc ggttggacgc attcagacgg cacgcaggtc
     2521 aaaccgcaca ttgagttcgg catcaaagcc gaaggagaag ccgtcaacct tttggacgcg
     2581 gcgtgggcgg aagtgttgca cagcttggac ggattgggag cagagctgaa aaatcgggta
     2641 aactgaaaac cgtttgccca aatcggacga tatttaagga aaaccatgca ataccgaatc
     2701 agaagagaaa acgaagcacc cgaagcaaaa aatgcggggg aaaccttatg ggagcgcgac
     2761 atcatgcgcg aagtgctgct gtccgcctat cgggacaggc gcagggagcg gatgtggaaa
     2821 aacatctggc gcgccgtcag caccctgatt ctggttgccc tgattgcagg cattttccaa
     2881 aaagacgaag ccgcattgca gttggcgggc aacacgccgc ataccgcagt cgtcaacctg
     2941 tacggcgaaa tcggcaacgg tgtagaagac caggtcaaaa aactcaaaga cggtatggag
     3001 gccgcctaca aaaacccgca ggcaaaagcc atcatcatcc gcgccaacag tccgggcggc
     3061 tctcccgtcg tatccaatac tgcctttgag gaaatacgcc gtctgaaagc gcaacatccc
     3121 ggcatccccg tttatctcgt ggcggaagat atgtgcgcgt ccggctgcta ctacatcgcg
     3181 gcggcggcgg acaaaatcta tgccgacccg tccagcatca tcggcagcat cggcgttatc
     3241 ggcagcagtt tcgacgcgac cggcctgatg gaaaaaatcg gcgtgaaacg cagggttaaa
     3301 attgcaggca gcaacaaagg catgggcgat ccgttttcgc ccgaaacgcc cgaacagtcg
     3361 aaaatctggg aagaaatgct gaccggcata cacggcgagt tcatcaaagc cgtcaaaacc
     3421 ggacgcggcg accgcctcaa attccgacaa tatcccgacg tgttcagcgg tcgcgtgtac
     3481 acaggcgcgg atgcgctgaa agtcgggctg gtggacggac tcggcaatat ttacagcgtg
     3541 gcgcgagacg tggtcaaagc ccccgatgtg gtggattaca ctccgaagga cgatttcggc
     3601 agaatcttgg gcagacgctt cggcgcagaa ctcaaagcaa gcgtgcgcga agccctgcag
     3661 gccgtccggt agcgttgttt acagtatttc taagggaata ccaaaataaa aatatacaca
     3721 aaaacactca cctccccagt atgctgccac taagtcagcc gcgtcactat ttaccgtgca
     3781 cttaaagccg taaaaggcag gttgtccccg ggaggttttg tgcatcctga taccgatcgg
     3841 ttgttgttgc tcaaaggaca gaaggccgct gataaacgag attacctgtt tgtcgctatt
     3901 gacgattttt atactctgcc attttgccgg acaaaaccgc agacagtgct gccaagtttc
     3961 tgaccgaaca tctgtccgac ccctgcttgt acctgattga gtacgtttac tctgacaatg
     4021 ataggtaata taaagagccg tccaacatgc tttcggtgca gcttgttatg ataatgggat
     4081 tggttggagg cttgcccgat ttgcttgtcc gcagaccaac ggtaaggcgg agcgggttat
     4141 ccgtaccttg atggagatgt ggcatgagga acagtcgttt gacagtccgg aacatcggca
     4201 aaaggagttg tgctgcttta ttaatttagg ggctgcccta gatcactagg gaaattcaaa
     4261 ttaagttaga attatcccta tgagaaaaag tcgtctaagc cggtataaac aaaataaact
     4321 cattttgtta tcgtggctat gatgtattgg atgcgggcga atttagccat ttccgtatca
     4381 atcacagcac acattttgcc gaacgacaaa accatattaa tggaactgag aacttttgga
     4441 atcaagcaaa acgtcattta cgcaagttta acggcattcc caaagcgcat tttgagctgt
     4501 atttaaagga gtgcgaatgg cgttttaaca acagtgaaat aaaagttctt gttccatttt
     4561 aaaacaatta gtaaaatcga gtttatccta gttgtccagg gcagcctcat ctctttatag
     4621 atagctgctt accaagtatc cttaattgct aattcaagcc aatcttcaaa actattaaaa
     4681 aattcatggt tttctatatt atctaaatta atgacaataa ccctagaatt tcctgttaca
     4741 tcattaccat caaaataagc ttcccattct ccattactag cgaatgggat aagatttaaa
     4801 tcaggcagga tagaatttct aaatatataa gctacttctg ccccttctgt tccataattc
     4861 tcaaaccacc agtgaaaatt atgtggctga atataaggta ttaaagatgt atcgttagag
     4921 atacgaacat acttttcagg ataacaaaac ctttcaggaa gcatattact aggatataaa
     4981 ttaaattcat tttgaataat catttcgtta ccttaggatc ataaatacta ccattaggaa
     5041 actgggtaga ccaatttggt ggtgctagtt cattttcaat ttgtttttta attctaaatt
     5101 gaatagcttc tccccatgtt tgcggcatct aatgctgctt gctctgcatc aatattacta
     5161 aaaattggat tagtctcaaa aatgaaaaat tactgttttt tcatttttta tagcatattc
     5221 aagtacatga ataatatttt tcactaaggg ctctgtagaa aaatctgaat tttgtaattt
     5281 ttcttttaca gccaaaatac tttccttatc tattagccaa tccccctcac ttggtccaaa
     5341 taaccaatta tcggtaattt cagaaacaag tctccataat ccacgatttt gatattcaat
     5401 aatttgattt tccgtaattt ctacaactgt ttcagattga atgtttttat aagcccaatc
     5461 aatcatttca gtatattcac taattgaaac attgtctttt aaacagaaaa ttaacaggtt
     5521 gtgttcattc atttgtctaa gttcctgata tgagtttgtt gttgtaaata atcttttgct
     5581 tgcttacctt gtaaattaaa ggattaaccg caccttggat gatgccgcga atatcatcca
     5641 tacggttacc ccaccaattt ttattggtgt atcgttaatc atttatttca aaaaagttat
     5701 ttattatcat attatcaggg agcaggtcgt taaaaaaaac cccctcaaat tccattaaat
     5761 tagtatttat ccagcacata aacgaaccaa agcgttcttt ccctgagtgt aaatatttaa
     5821 aattaaactc aaaataagtt tttttgctta gaaaatttaa tggtttttct atagtgaaaa
     5881 aaaagccctt actcgttttc gttcgagata ctattttaaa taaattttta ttttcaataa
     5941 aataagaata ttcatttact aagttgttat gataaaaaag taattttatt aaaatgtttt
     6001 cataattttc taggttcatt tctagctcaa tttaaaatga tttcattgtt gccgtaccaa
     6061 tgcgaaattt accatcaaca aaatttccct tcactgatac aggtacacca tcaacttggg
     6121 tagttttatt ttcaggctgc ctgaaagaaa gataggcaac ttattactca tcttacgcta
     6181 gccctcaata attgaatacg ttgcactaga accaattatt tctatgaatg tttgctcaaa
     6241 cataaaaata tagtatttaa agaattctct attcaaagga aaataacttt ctttcagtat
     6301 ccattccgca taacactcat caagaagttc aaaaaaagat tgaccaccat tttcatgaag
     6361 caaagctcta tctgcatctt ccgaaattaa atccataaaa gtatctataa aatacgattc
     6421 atcaacaacc ctaaaatgaa taacatcttc aataaaaatt tttatggttt tatccgtatt
     6481 tctataacca actgctataa cttctacttt atcagagttt attgctgcat tatcaaaata
     6541 gaaatagcca gttgggaaat ctaagctttt taatttcata atttatcgtg tatttccata
     6601 tctgattttt atttttcggt tattactaat tgttatttca agtgttggtt ctccaccact
     6661 actatcatta cgagcattaa ccgcacgccc atcaggtaaa ttgcccgtta tcgttccatt
     6721 aggacgtgtt tgtacatttc gaacattcag actattaaaa tcatttagtg cgtcattgta
     6781 atcccccact ttatcatact gaacagcggg accttttgtt ttactccttt gagtagtatt
     6841 gctcaaaatg tctttgattt gtaaatcact gcgcgcctta ccggcttcta tgcgagctgc
     6901 cacactactc gggctatagg ggtcgctatc aatcgcagga ttaccaccgc tggttttttg
     6961 tccgctagcc tgtttcccaa cctgctgtac tgtatcgcca atttcatcta ccgtacctaa
     7021 cgccttagtc tgcatatggc gaacagcagg ttttttatag ccggtatttt taacccaatc
     7081 ccatttggtc gggttaagtt ctactttttt acctctccaa accgtacctg cggcctctgc
     7141 tacggcaagg gcagtttggg ctgttgctgt tatattcgga tgggcatcag cccattgtct
     7201 ggcggaattg atgccgtctt ttaccgcaaa agcactgtcc tgtaatatgc tcgcggcagc
     7261 aagttgtgct tccgggctta attttcctga attattaata ccttgtagag tctgctgcgc
     7321 agagatgtag caactgtatt tttaccccgt cgggtaaaaa tacagttgct acggctgctg
     7381 ggaaagcagt tactattttc ccagtggctc aaaattaatt gtttcagcag atatttttat
     7441 aataatccct acatcaataa taatttcact ataaaattgg tatttatata gctctatttc
     7501 gggtataaac aagggaaaca agctatcttc cttatcctca taatctacga aattatttgt
     7561 atctaattta aaattcaaaa tattactgca tttgatatat ccgaaataat taccttcaat
     7621 tgtatctgta aaagataatg taagggtatt tccattatcg gaaaagatta tttcataaag
     7681 gcttacattg tgaaaaatat tttttttcat ttgacaaaat atccagaatg atgatgatta
     7741 tttggcaatg gattgccttc ataatcttgt cgttgcggat attttccctg tacaccatcg
     7801 gttcgcggca ctctttgggt tcttataacc tctccatttg gacgaatatc tattttcacg
     7861 ccatcaggac ctttccatgt ttcatattga gccgcatctg aaccagtacg tctaaaacct
     7921 tgttcttgca atgcttgacg taattcatct cgcgtagttg gtctgataga tttaacaact
     7981 ggcttgtttc ctcctgccat ctcaccgtcc aacgtctgca tagggcgggc agcaggtgtt
     8041 ttatagccgt tatttttaac ccaatcctat ttggtcgggt taagttctac ttttttacct
     8101 ctccaaaccg tacctgcggc ctctgctacg gcaagggcag tttgggctgt tgcagttata
     8161 ttcggatggg catcagccca ttgtctggcg gaattgatac cgtcttttac cgcaaaagta
     8221 ctgtcctata atgcgcttgc ggcagcaagt tgtgctttcg gacttaaatt tcctaaatca
     8281 ttaatacctt gtaaagtttg ctgcgcagag atgtaggtcg gatatttgta tccgacaaaa
     8341 atatttgacg catctatcgt ttccgaaatg ccgctgttgg aaaatgtcgg attcgagaat
     8401 ccgacctacg gctatttcgt ttaagtcata aatagccatt catgttcctt ctgaatttgc
     8461 ttttgctatc cttagaacca atcatataaa cattatcatc attaattaat gttctaagtt
     8521 tatgaagcgg tcaaatctgt caaactacca gagatgaagc atatcctcct ggaagtaatt
     8581 ctgttcgtgc tgtttccata tcttctttgc catcatcagt tacttctctg tctaaataaa
     8641 atcttacgat aagtttttgt ctaatttcat caaattctgc cgtaattaat cttatattga
     8701 tatgaataca cggttcatac ctgctattag ccagtcaggt gtagttggat ggggattcat
     8761 ttttaataat atcttcaagc aagtgaaatg taagaaaagc gtagatactt gaaggccggc
     8821 tatctgattg gcaaaaagaa atttcggaga taaagaattt ccgtttatat ttttcataaa
     8881 ttaaatcaac accttgtttt acataaaaac taacttcctc aggaaggata tttataacat
     8941 tctctccttt tacttttata gttaatggtt tgatttttat gttttcatga atatctgata
     9001 ggattatttc taaaaaatta tttttatttc cagtcattct ggctatttta tgtatatttc
     9061 cattgtgttc gattatcatt ttattttttc caaggatttc cttctatatt gatagtttat
     9121 ctaaagattt catttaaaat atcctgacta atttcttgtt tatataattc tacaattttc
     9181 tgtttctgtg tatttgtata aaatttttcg ttggtatctg cttgatattt taattgtctc
     9241 aatatttcca tgatttcata ttctgatttt tcatcatatt cttcaatcat gtaatcaaca
     9301 aattgtttta gaatatcaaa ggcttcgtaa ctttccaaaa ttttaatatg tttatcggca
     9361 aaattggaca tataccattc gtcagtgatt ggattagtat ttaaatcatc taaaaaaaca
     9421 tttaaatcat ctaaaaaaac atttacatca tctaaaaaca tgactaatcc ttaaacttaa
     9481 aatctgtttt ctcaccggtt cttgagtttt caatgtaatg tatttcaatt ttgtttacgt
     9541 tttgaacacg cttaacccaa ccgtcttttg ctaaccaacc atttttagta tcggacatag
     9601 gaggtattct cgcaggagtt ttgccctgtg ggtttgcctt aacttcttcc attgctaatt
     9661 gttcctttaa attattaggt attgtacgac cggttgattt ttcaacagat tgtgtcccta
     9721 tttttaatga tttgtttccc ccagccattt ccccgtctac agtctgcata gggcgggcag
     9781 caggtttttt atagccggta tttttaaccc aatcccattt agtcgggtta agttctactt
     9841 ttttaccgcg ccaaaccgta cctgcggcct ctgctacgga aagggcagtt tgggctgttg
     9901 cagttatatt cggatgggca tcagcccatt gtctggcgga attaatgccg ttttttaccg
     9961 caaaagcact gtcctgtaat aggctcgcgg cagcaagttg tgcttccgga cttaaatttc
    10021 ctaaatcatt aataccttgt agagtctgct gagcggctgt atctgagccg gtcagtgtag
    10081 gttggattaa aacccagcat tttcaacatc ttgatgtttt actataaatc tattcttgtg
    10141 cttcctttgt tagataaatt tcaacacaaa agatacgtat gcattctcta attttatttg
    10201 agataaataa tgcattgctt tgtcgatact gttaaataaa ttacttccct cgtaatacca
    10261 attatcatat gtttgataaa aataattatc tttcttgata taaatatctc cccccaatac
    10321 aagtattctc tcattgataa ataaatttaa tatatctatt gcaataggga cgggtaatgc
    10381 ggcttctcta attccaattc ctatcaaaga ttccccttgt ctcgaataaa tttcaaaaat
    10441 ttcatttaac atgttaatct ctatctacta tttttcaatc ggtataaacc ctattcacag
    10501 tttcatcttg tatttcttta tgaatactta atatattaag atagcttagg aattttattt
    10561 tctcagattg aggcaactca tcaaaaccaa gccaacaata aaaattgtta tatgatttta
    10621 aaaaatcaac aatttttatt tttcctaaaa ccaaatcttc gactaactgg gttgcataaa
    10681 taatatcatt tatgatttta acaggtaaat tatttgatag gtaaccatgg gattccgtca
    10741 tcattgattt ctctaggtgc ttatttatct gattggtaag ccttttgcgt aagcttcttt
    10801 cgcctccgca agtgtcattt cattagggcc accatctata ttagtttctc ctgtattttg
    10861 ccactgacaa acgtcacaga tatcatagtc cataacttca gttccgcaaa caggacaatg
    10921 tagccatatt tctccgtcaa tttcccatgt cttttttgaa ttctccatca taatacttct
    10981 ttcctaagtt tggtttaaac attgttttga ttttgaatgt ttttggattg gccaaaacat
    11041 agatattgtt attgatatca tagcgcactc gtctatgttc cgtctgataa cctaatatct
    11101 tgtccgatgt ctgttttgat aacaaatcag acgccatttt ttggtagtct tcaatggtta
    11161 tatcgccaaa ttcttttcca tgagctttga aatgtccatt taaagatttc tcagtaggaa
    11221 acttggactt tgtccatctg atgcggtctt gaattgttcc tgtcggagaa atagatgtat
    11281 caggtttaac atatgaggca ggtaagccga tattgttatc agagtgtgta gggtgttgct
    11341 gcgtacttgg ttttggtggc ttattcccac ctgccatctc cccatctaaa gtctgcatag
    11401 ggcgggcagc aggtgtttta tagccggtat ttttaaccca atcccatttg gtcgggttaa
    11461 ggtttacttt tttaccgccc caaaccgtag ttgcggcttc tgctacggaa agggcagttt
    11521 gggctgttgc agttatattc ggatgggcat cagcccattg tctggcggaa ttaatgccgt
    11581 cttttaccgc aaaagcactg tcctgtaata ggctcgcggc agcaagttgt gcttccggac
    11641 ttaaatttcc taattcatta atatcttgta aagtttgctg cgcagagatg taggtcggat
    11701 atttgtatcc gacaaaaata tttgacgcgt ctatcgtttc cgaaatgccg ctgttgaaaa
    11761 acgtcggatt cgagaatccg acctacggct gctaccaacc atcattttca gcttctttta
    11821 gccaagtatc aaaattttca aaagtctcgt aatattttgt attatctaaa ttaactacta
    11881 taattttagg attacctgat ttatctgaaa tatcaaaaca ggcagcccac tcttggtttc
    11941 tagcaaaagg taataggttt ggaatgccag ttatttcaaa ataaatgtca attacttctg
    12001 atatattgct ttctgcattt tcaaaccacc aaggaaaaga atattgttca tcgtagttaa
    12061 tggcatgagt ggattgagct aattttaaat aactttgcgg atatttaaat cctttaggaa
    12121 gcattgcttc aggatacgga acaaaactat tttgttttat catttcctaa gtacctttac
    12181 atcataaata cttccgttag gaaatctttt gctccaccct tctggaactc ctttttgtgt
    12241 ttcttgcttt ctaattcgta gctggatagc ttctccccaa gtttgaggct caataccatc
    12301 atgcttaaac ctgattctct cttttgatga taatcggtca ttaaaattat gaacattcgc
    12361 ttccactttt acccctgctt cacgtgctgc cataatacgc gtgttatcca tactagtagg
    12421 tgctccatca ggcatattaa caacatcaac cctgtcgcca acccatgatt tttttctttc
    12481 atttcggcta caatagaatc atagttgtaa tttgcactag gctctgacaa aaatttgggt
    12541 tgttaagttg tcattttttt ataaattcca gcaaactgtt gttgtaaatt atctacttca
    12601 tgttttctaa caccagatac attttcaaat tctcttgaat ctacacatac gcccgcatat
    12661 atctcattca agatagctcg taaaacaaaa acttcatctt gagttagtga aatagttgag
    12721 ttttgattat ttatggatag tatattcatg gctttttcct ataaatcatc ataatatttt
    12781 ttacctgatg ttggtctaaa tgctgtacct ccatcgtcag aatttttatc tcggataact
    12841 attgtccctg ttttatcatc ccaatacgca gttctaccgc gaggtaactc tttcatattt
    12901 gttggatggc taacaatatt ttcaatatgc cgagcaaaat ctgctggtga attgatattt
    12961 aaatccgtaa attcttgttg tcttatgaca tgcttgttat aagcatgccc actactaatt
    13021 tgttctccaa ttagttgcgc ttgtaaagac ggttgtgtgg aagcatctgc tttgctgttg
    13081 gacgttatag atttaggcgg tctattcccc cctgccatct ccccatctac agtctgcata
    13141 tggcgggcag caggtttttt atagccggta tttttaaccc aatcccattt ggtcgggtta
    13201 agttctactt ttttaccgcc ccaaaccgta gttgc
//
LOCUS       DAXIDM010000049        12925 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000049 DAXIDM010000000
VERSION     DAXIDM010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12925
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.049"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(95..403)
                     /locus_tag="ACFOAE_001214"
     CDS             complement(95..403)
                     /locus_tag="ACFOAE_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884696.1"
                     /translation="MTNNVDLKVPAKRYFTLDELCGLLQISPYGFAQWQHDHGVVVGY
                     GGERYTRLDVVKLLKLQSTFAPYAEGAESGSDGNRPVTLQEIGDGLKELLADLDKELC
                     "
     gene            complement(387..689)
                     /locus_tag="ACFOAE_001215"
     CDS             complement(387..689)
                     /locus_tag="ACFOAE_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002641098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HFC6884697.1"
                     /translation="MTLTKAELADILVDKVSNVTKNDAKEIVELFFEEIRSTLASGEE
                     IKISGFGNFQLRDKPQRPGRNPKTGEEVPITARRVVTFHASQKLKSMVEHYYDKQR"
     gene            complement(763..3126)
                     /gene="pheT"
                     /locus_tag="ACFOAE_001216"
     CDS             complement(763..3126)
                     /gene="pheT"
                     /locus_tag="ACFOAE_001216"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFC6884698.1"
                     /translation="MQFSYSWLKTQADTELSSDKLEHLLTMSGLEVEEAETAAPAFAG
                     VVIAEVKSVEKHPDADRLNVTQVDAGTGELVQIVCGAPNVKPGIKVPCSLPGAVLPGN
                     FKIKPTKMRGVPSNGMLCSTNELGLPDDGVDGLHILPEDAPVGTNIREYLDLDDTLFT
                     LKITPNRADCLSVKGIAREVSALTGCAFRQPEIHTAPITGSRKQPVQINAPADCGRFI
                     SRVIENVNAKAATPDWMKQRLERSGIRSISALVDIGNYVMLEIGQPMHVFDADKLSGS
                     LHIRRAREGETLECLNEKTVSLSENTLVVADEKGVLSLAGVMGGAASAVSDGTQNIVL
                     EAAWFAPEIIAGKSRQYGFGSDSSFRFERGVDYRLQADAIERATELVLQICGGAAGEM
                     VEAQGELPEAKQVGLRLGRLKTVLGVDIPAEQVETILQHLGLQPEKTAEGFRVTAPSF
                     RFDIEIEADLIEEIGRVYGYENIPDDYTSGRLKMLELPETRRPRFAVYNEMAARGYRE
                     VVSYAFVDEQWEQDFAANADPIRLQNPLAAQYAVMRSTLIGGLVEILQNNLNRKQNRV
                     CVFEIARVFSKGSDGQFVQNERIGGLWYGAVMPEQWGGKTRNADFYDIKADVENLLKN
                     KAVEFVKTGHPALHPGRAANIVSDGKVIGFVGELHPKWLQKYDLPQAPLVFEIDMAAV
                     LECGKTRYRAVSKFQPVRRDLAFVMPEAMSHDDLLLVLKGAANKLVQEISVFDVYRGT
                     GLPEGMKSVAVKVILQDMENTLTDEAVEPLIGKLIGAATAAGARLRS"
     gene            complement(3162..3680)
                     /locus_tag="ACFOAE_001217"
     CDS             complement(3162..3680)
                     /locus_tag="ACFOAE_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884699.1"
                     /translation="MSEIINLTESGITFNLVKNNLFYIEPYIRKRRQEGIKTVEFIYL
                     QEDNLLFVEAKQSIPNQERSPERFDEYISEIYQKWCNALNVEILGILGREDIKETIMP
                     SAFSNLQWGSIEIKLLLVIPDVPLNYLGQLNELIKQEFNKKDTLRLISLWNISVEVIN
                     RDLAIQKGLASS"
     gene            complement(3687..4751)
                     /locus_tag="ACFOAE_001218"
     CDS             complement(3687..4751)
                     /locus_tag="ACFOAE_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFC6884700.1"
                     /translation="MIKSFELEKFGPISLLKADNLGKINLIIAENSKGKTFILKALYS
                     VLKSHEEAHKGKNIRDFSEELRDKLYWTFQVEEIGDLVTRGKENPNERPLKLSMTLED
                     SSSVLFSFGRTTKKLIKPELYELSPRINANSIFLPPKEVLSLFDVIKKSEEEKRFGFD
                     ATYIDLVKALDIKPTKGRNYPEAAEARKDLEALFGGYVSYNDKKKAWVYEKDRQTFSI
                     NSTAEGVKKIGILDTLLGNRFLSPGSILFIDEPEANLHPKAINQFLEILFSLSKSKLG
                     IQIFMSTHSYFVIKKLCLLARKHSESIPVFMPGKEKEQTTWVQENLQNSMPDNEIIGE
                     SIRLFREEIGVLSPETAWIG"
     gene            complement(4928..5920)
                     /gene="pheS"
                     /locus_tag="ACFOAE_001219"
     CDS             complement(4928..5920)
                     /gene="pheS"
                     /locus_tag="ACFOAE_001219"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFC6884701.1"
                     /translation="MENVNRIVAEGIAAVEAAQDFNALEQIKARYLGKTGELTGLLKT
                     LGQMSPEERKTIGAHINECKNRFQTAFNAKRDALNEVKLQARLAAEALDITLPGRAQE
                     GGSLHPVTLTLQRVVELFHGMGFEVADGPEIEDDFHNFQALNIPANHPARAMQDTFYV
                     ENGDVLRTHTSPIQIRYMLDKKEPPIRIIAPGRVYRVDSDATHSPMFHQAEGLWVEEG
                     VTFADLKAVFTDFIRRFFERDDLQVRFRPSFFPFTEPSAEIDIMGENGKWLEVGGCGM
                     VHPNVLKNVNIDPEKYTGFAFGIGLDRFAMLRYNVNDLRLFFDNDLNFLKQFVK"
     gene            complement(6266..6625)
                     /gene="rplT"
                     /locus_tag="ACFOAE_001220"
     CDS             complement(6266..6625)
                     /gene="rplT"
                     /locus_tag="ACFOAE_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFC6884702.1"
                     /translation="MPRVKRGVTARARHQKIFALAKGYRGRRKNVYRVAKQAVMKAGQ
                     YAYRDRRQRKRQFRQLWIVRINAGARENGLSYSKFMNGLKRASIEIDRKVLADLAVFD
                     KAAFAQLVEKAKAALAA"
     gene            complement(6638..6835)
                     /gene="rpmI"
                     /locus_tag="ACFOAE_001221"
     CDS             complement(6638..6835)
                     /gene="rpmI"
                     /locus_tag="ACFOAE_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFC6884703.1"
                     /translation="MPKMKTKSSAKKRFKVLGNGGVKRAHAFKRHILTKKTTKNKRQL
                     RGTSMVNDRDLASVAKMLPYA"
     gene            complement(6982..7503)
                     /gene="infC"
                     /locus_tag="ACFOAE_001222"
     CDS             complement(6982..7503)
                     /gene="infC"
                     /locus_tag="ACFOAE_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFC6884704.1"
                     /translation="MIAQEREARINGEITAKEVRLISESGEQLGVVSVREALAMAEGQ
                     DVDLVEISPTAKPPVCKLMDYGKYKYQQAKKRDEAKKNQKQVQIKEIKFRPGTDEGDY
                     QIKMRNINRFLADGDKVKVTLRFRGREMAHQQLGAQLLERVKEDLAEVAQIESFPKME
                     GRQMVMMIAPKKK"
     gene            complement(7521..9434)
                     /gene="thrS"
                     /locus_tag="ACFOAE_001223"
     CDS             complement(7521..9434)
                     /gene="thrS"
                     /locus_tag="ACFOAE_001223"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFC6884705.1"
                     /translation="MLNITLPDGSVRQYESPVTVAQIAASIGAGLAKATVAGRVNGKL
                     VDACDPIVENSAVQIITPKDQEGIEIIRHSCAHLVGHAVKQLYPNAKMVIGPVIEEGF
                     YYDIATEKPFTPEDVAAIEARMKELIAQDYDVVKIMTPRAEAIKIFQERGEEYKLRLI
                     DDMSEVEAMGMYHHQEYVDMCRGPHVPNTRFLKNFKLTKLAGAYWRGDSNNEMLQRIY
                     GTAWATKDELKAYIQRIEEAEKRDHRKLGKQLDLFHLQDEAPGMVFWHPKGWALWQVI
                     EQHMRKELNAAGYKEVKTPQIMDKTFWEKSGHWENYKDNMFVTSSEKREYAVKPMNCP
                     GHVQIFNNGLRSYRDLPMRLAEFGSCHRNEPSGALHGLMRVRGFVQDDAHIFCTEDQI
                     VSEARAFNELLVRIYKQFGFHDVSVKLSLRPEQRAGSDDVWDKAEQGLREALTACGVE
                     WGELPGEGAFYGPKIEYHVRDALGRSWQCGTLQLDFVLPERLDAEYVTENNDRARPVM
                     LHRAILGSLERFIGILIENYAGSFPLWLAPVQLVIMNITENQADYCREVAAKLQAAGF
                     RVELDLRNEKIGYKIRDNSQYRFPYQIVVGDKEKQENKVAVRRKAEDLGSLDLDDFIA
                     QLQQEITDALVNH"
     gene            complement(9487..9563)
                     /locus_tag="ACFOAE_001224"
     tRNA            complement(9487..9563)
                     /locus_tag="ACFOAE_001224"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9527..9529),aa:Val,seq:gac)
     gene            9742..10857
                     /gene="tgt"
                     /locus_tag="ACFOAE_001225"
     CDS             9742..10857
                     /gene="tgt"
                     /locus_tag="ACFOAE_001225"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFC6884706.1"
                     /translation="MLKFTLHKKDGYARRGTLELNHGKIETPVFMPVGTYGSVKAMNP
                     QNLHDIKAQIILGNTYHLWLRPGLEVVEQFGGLHGFIGWDKPILTDSGGFQVFSLSDM
                     RKLTEEGCTFKSPINGDKLFLSPEISMKIQTVLNSDIAMQLDECTPGEATREQARKSL
                     QMSLRWAERSKKAFEDLKNPNALFGIVQGAMYEDLREESLRGLEQFDFPGLAVGGLSV
                     GEPKPEMYRMLRAVGPILPEHKPHYLMGVGTPEDLVYGVAHGIDMFDCVMPTRNARNG
                     WLFTRFGDLKIKNAKHKLDKRPIDESCTCYACQNFSRAYLHHLHRAGEILGAQLNTIH
                     NLHFYQVIMAEMRDAIEQGKFADWQAQFHENRARGTD"
     gene            10867..11949
                     /gene="hemH"
                     /locus_tag="ACFOAE_001226"
     CDS             10867..11949
                     /gene="hemH"
                     /locus_tag="ACFOAE_001226"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HFC6884707.1"
                     /translation="MPSEAASDGILPLYPTRTIFQKPIMLPFFPEPSLSYTQQNRTAV
                     LLLNLGTPDAPTAQAVRPYLKSFLTDRRIVELPKWLWYPILHGLVLTLRPKKSAHAYE
                     KIWFKEGSPLEVYTARQAAALAERMPDLIVRHAMTYGNPSVADVLSELKAQGAGRLLV
                     IPMYPQYAASSSGAAVDKVCEQLLLQRNQMSVRTVSRFYDDTGYIDAMKNHILRYWAE
                     HGRGKKLMLSFHGVPQKHYDLGDPYPDECRHTAKLLAEALELTEDQYVVSFQSQFGRA
                     KWVTPSTQDLFGKLPKQGVTELDVFCPGFLADCLETMEEIALMGREQFYEAGGKSYRY
                     IPCLNDNPDWIDALVALAEENLGGWR"
     gene            12141..12542
                     /locus_tag="ACFOAE_001227"
     CDS             12141..12542
                     /locus_tag="ACFOAE_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC6884708.1"
                     /translation="MNTTRLPTALVLGCLCAAASAADNSIMTKGQKVYESNCVACHGK
                     KGEGRGTMFPPLYRSDFIMKKPQVLLHSMVKGINGTIKVNGKTYNGFMPATAISDADI
                     AAVATYIMNAFDNGGGSVTEKDVKQAKGKKN"
     gene            complement(12605..12895)
                     /locus_tag="ACFOAE_001228"
     CDS             complement(12605..12895)
                     /locus_tag="ACFOAE_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003696797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884709.1"
                     /translation="MAKYFTETGISVREYFDFFGEFVVLPAARSGDLALAYGLRLEAG
                     EEGLSLAELFDKRSDSQEPVECGRIDIGGFMLTAKEVDGGGNIGSMGLKVPR"
BASE COUNT         3309 a         3394 c         2846 g         3376 t
ORIGIN      
        1 gcttcgtcgc cttgtcctga tttttgttaa tccactataa ttatttttta gcgtgtaaaa
       61 caaaaccggc tgcatacctg caaccggcct caaatcagca caattcctta tccaaatccg
      121 ccaacagctc tttcagaccg tctccgattt cctgaagcgt aaccggacgg ttgccgtccg
      181 aacccgactc cgcaccttct gcatacggtg caaacgtgct ctgcaatttc aacagtttca
      241 ccacatccaa acgggtgtag cgttcgccgc cgtaaccgac aaccacaccg tgatcatgct
      301 gccattgcgc aaaaccatag gggctgattt gcaacagtcc gcacaactcg tccagcgtga
      361 aatagcgttt tgcgggaacc ttcaaatcaa cgttgtttgt catagtagtg ttccaccatg
      421 cttttgagtt tctggctggc atggaaagtt accacgcggc gggcggtaat cggcacttcc
      481 tcgccggttt taggattacg acccgggcgt tgcggcttgt cgcgcaactg gaaatttccg
      541 aaaccggaaa ttttgatttc ttcgccgctt gccaaagtgc tgcggatttc ttcaaaaaag
      601 agttcgacga tttctttggc atcgtttttg gtgacgttgc tgactttgtc taccaaaata
      661 tcggccagtt ctgctttagt gagagtcata tgattacctt ctgttgtaac agttgtggat
      721 tattaccaat ttttatttaa aattcaagcg aatatttatt ttttaactgc gaagccgcgc
      781 ccctgccgcc gttgccgcgc caatcagttt tccgataagc ggctcgactg cctcatccgt
      841 cagcgtgttt tccatatcct gcaaaatcac tttgaccgcc acgctcttca tcccttcggg
      901 cagtcccgtg ccgcgataca cgtcaaacac gctgatttcc tgtaccaact tgtttgccgc
      961 gcctttcaag acaagcagca aatcatcatg gctcatagct tccggcatca caaacgccaa
     1021 atcgcggcgc accggctgga atttcgatac ggcccgatag cgcgttttcc cgcattccaa
     1081 cacggccgcc atatcgattt caaataccag cggcgcttgc ggcaggtcgt atttttgcag
     1141 ccatttcgga tgcagttcgc cgacaaagcc gatgactttg ccgtctgaaa cgatattggc
     1201 ggcgcgtccg ggatgcaggg caggatgtcc ggttttaacg aactcgactg ctttgttttt
     1261 caacagattt tccacatctg ccttgatgtc gtaaaaatcc gcattgcgcg ttttcccgcc
     1321 ccattgttcc ggcatgaccg cgccgtacca caatccgccg atgcgttcgt tttggacaaa
     1381 ctggccgtct gaacctttgc tgaacacgcg ggcgatttca aacacgcaca cgcggttttg
     1441 tttgcggttc agattgtttt gcagaatttc caccaagccg ccgatgagcg tggaacgcat
     1501 cacggcatac tgcgccgcca gcgggttttg caggcggatg gggtcggcgt tggcggcaaa
     1561 atcttgttcc cactgctcgt caacgaaggc atagctgacc acttcgcggt aaccgcgagc
     1621 cgccatttcg ttgtaaacgg caaaacgcgg gcggcgtgtt tcgggcagtt ccagcatttt
     1681 cagacggcct gacgtgtaat cgtcggggat gttttcatag ccgtaaacgc gtccgatttc
     1741 ttcaatcaaa tcagcctcaa tttcgatgtc aaaacggaag ctcggcgcgg taacgcggaa
     1801 gccttccgcc gttttctcgg gctgcaggcc caagtgttgc aaaatggttt ccacctgttc
     1861 ggcaggaatg tccacgccca acacggtttt cagacggccc aaacgcaatc caacctgctt
     1921 cgcttcaggc aattcgcctt gcgcttccac catctcgcct gccgcaccac cgcaaatctg
     1981 caacaccaat tcggtagcac gttcaatggc atccgcctgc aaacggtaat ccacgccgcg
     2041 ctcgaagcgg aacgacgaat ccgaaccgaa accgtattgg cgcgatttgc cggcgatgat
     2101 ttcgggcgca aaccaagccg cttccagcac gatattttgc gtgccgtctg aaaccgcgct
     2161 cgccgcgccg cccattacgc ccgccaaact caacacgcct ttttcgtccg ccacgaccag
     2221 cgtgttttca gacagggaaa cggttttctc gttcaggcat tccagcgttt ccccttcgcg
     2281 cgcgcggcgg atgtgcaggc tgccggaaag tttgtcggca tcaaaaacgt gcatcggctg
     2341 accgatttcc agcatcacat aattgccgat gtccaccagc gcggaaatac tgcggatgcc
     2401 gctgcgctcc aaacgttgtt tcatccaatc gggagtagcc gctttcgcat tgacattttc
     2461 aataacgcgg ctgataaaac ggccgcaatc ggcaggcgcg ttaatctgca cgggctgttt
     2521 tcgactgcct gtgatcggcg cggtatggat ttcgggctgc ctgaacgcgc accccgtcaa
     2581 tgcggacact tcgcgcgcaa tacccttaac gctcaagcag tcagcgcggt taggcgtaat
     2641 tttcaacgta aacagcgtat cgtccaaatc caagtattcg cggatgttag taccgacagg
     2701 cgcatcttca ggcagaatgt gcagaccgtc tacaccatca tcaggcaaac ccagttcatt
     2761 ggtcgaacac aacataccgt ttgatggtac gccgcgcatt ttagtcggct taattttaaa
     2821 gttacccggc aaaacggcac ccggcaacga acacggcact ttaatacccg gcttgacatt
     2881 cggcgcacca caaacaatct gaaccaactc gcccgtaccg gcatcaactt gggtaacgtt
     2941 caaacggtct gcatcaggat gtttttcaac ggatttcact tcggcaatca ccacgcccgc
     3001 aaacgcaggc gcggcagttt cggcctcttc cacttccaag ccggacatcg ttaacagatg
     3061 ttccagctta tcggaggaaa gttcggtatc ggcttgggtt ttcagccatg agtaggagaa
     3121 ttgcatgtta tgttctcaat taactaatta actttagatt ttcaagagct agctaaacct
     3181 ttttgaatgg ctaagtccct attaattact tctacagaaa tgttccataa agaaatcaac
     3241 cgcaaagtat ctttcttatt aaattcttgc tttattaatt cattcaattg cccaagataa
     3301 ttaagcggca catccgggat aaccagtaat aatttgattt ctatgctacc ccattgcaaa
     3361 tttgaaaaag cactaggcat aattgtttct ttgatatctt ctctgcctaa tattcccaaa
     3421 atttcaacat ttaatgcatt acaccatttt tgataaatct ctgaaatata ttcatcaaaa
     3481 cgctcaggag atctttcttg atttggaata ctttgttttg cctcaacaaa taacaaatta
     3541 tcttcttgca gatagataaa ctctactgtc ttaatacctt cttgccttct cttccggata
     3601 tatggttcta tataaaacag gttatttttt actagattaa aagttatacc tgattcagtg
     3661 agatttatta tttcactcat aaaaacctaa ccaatccatg ctgtttccgg agataaaaca
     3721 cctatttctt ctctgaacaa tcgaatagac tcaccaataa tttcattatc cggcatgcta
     3781 ttttgtaaat tttcctgcac ccaagtagtc tgttcctttt ctttgccagg cataaaaaca
     3841 ggaatacttt cactatgctt tctagctaat aaacacagct tcttgataac aaaatatgaa
     3901 tgcgtactca taaaaatctg tattcccaat ttggatttag ataaggaaaa cagaatttct
     3961 agaaattgat taattgcttt cggatgtaga ttagcttctg gctcatcaat aaataagatt
     4021 gatccaggac tcaaaaaccg atttcctaat agagtgtcta atatcccaat cttttttacc
     4081 ccctctgctg tagaattgat agagaaagtt tgtctatctt tttcatatac ccatgccttc
     4141 tttttatcat tgtagctaac ataaccgcca aacaatgctt ctagatcctt tctagcttcc
     4201 gctgcctcag ggtaattcct cccttttgtt ggtttaatat ccaatgcttt taccaaatca
     4261 atgtaagtag catcaaaacc aaatctcttt tcttcctctg attttttaat tacatcaaat
     4321 agtgatagaa cttctttggg tggtaaaaaa atagagttag cgtttattct gggagaaagt
     4381 tcgtatagct ccggtttaat tagctttttg gtagttctac caaaagaaaa caaaactgaa
     4441 gaactatctt ctaaagtcat acttaactta agaggccgtt cgtttggatt ttcttttcct
     4501 cttgtaacta aatcaccaat ttcctctact tggaacgtcc aatatagctt atctcgcaat
     4561 tcctcagaaa aatcacgaat attctttcct ttatgagctt cctcatggct ttttaaaaca
     4621 ctatataatg cctttaaaat aaaagttttc cctttgctat tttctgcaat aattaaattt
     4681 attttcccta aattatcagc cttcaataag ctaatcggtc cgaatttttc aagctcaaat
     4741 gatttaatca tataatcccc ctaatatata tcaacaatat ttgtacaagc cacattgtaa
     4801 aaagacagca accacagcac catagtaaac gcatagcagg cggataatgg agcgacatag
     4861 cgtttcatga tttagctttc tgaggtaggc acaggctgct tttttcattt ttaggcagcc
     4921 tacacaatca ttttacaaac tgcttcaaaa aattcaaatc gttatcaaaa aacaagcgca
     4981 gatcattaac gttgtaacgc agcatcgcaa aacggtcgag accgataccg aaagcgaaac
     5041 cggtatattt ttcagggtcg atattgacgt ttttcaacac gttgggatgt accatgccgc
     5101 agccgccgac ttccagccat ttgccgtttt cgcccataat gtcgatttcg gcggacggtt
     5161 cggtaaacgg gaagaaagac gggcggaaac gtacttgcaa atcatcgcgt tcaaaaaagc
     5221 ggcggataaa gtcggtgaac acggctttca aatcggcgaa ggttacgccc tcttctaccc
     5281 acaaaccttc cgcctgatgg aacataggcg agtgcgtggc atcgctgtcc acacggtaaa
     5341 cgcggccggg agcgataatg cggatgggcg gctctttttt atcgagcata tagcggattt
     5401 gaatcgggga agtgtgcgta cgcaaaacat cgccgttttc aacgtaaaac gtatcctgca
     5461 tcgcacgggc aggatggttt gcagggatgt tcagggcttg gaaattgtga aaatcgtctt
     5521 cgatttcagg cccgtccgcc acttcgaaac ccattccgtg aaagagttcg accacacgtt
     5581 gcaaggtcag ggttacggga tgcaggctgc cgccttcctg agcgcgtccg ggcagggtaa
     5641 tatcgagggc ttcggcggca agtcgggctt gcagcttgac ttcgttgagg gcatcgcgtt
     5701 tggcattaaa agccgtctga aaccggtttt tgcattcatt gatatgcgca cctatggttt
     5761 tgcgctcttc aggcgacatt tgccccaaag ttttcagaag tccggtcaac tcgccggttt
     5821 tgccaagata acgggctttg atttgttcta gagcgttgaa gtcttgcgca gcttctactg
     5881 cggcaatgcc ttctgcaacg atgcggttta cattttccat aatatcaagt ctgtcaatta
     5941 atgatatgcc acctgaaaca acgaggccgc ctgtatagcc tgacatatca gactcttcag
     6001 acgaccttat tttcttcacg gtcaatccat tggataaatt ttctgtatag tggattaaat
     6061 ttaaaccagt acggcgttgc ctcgccttgc cgtactatct gtactgtctg cggcttcgtc
     6121 gccttgtcct gatttaaatt taatccacta tattttaacg caaatttatt taaaaaaata
     6181 gactttaaag aaagaaaatc aatcacatag aatttctgca aacaaagaaa aaaggaagcc
     6241 gcagcttcct tttcaatttt ttggattaag cagccaaagc agctttggct ttttcaacca
     6301 attgtgcaaa agcggcttta tcgaacacgg ccaaatcagc caatactttg cggtcgattt
     6361 caatagaggc gcgtttcaga ccattcataa atttgctgta agacaacccg ttttcacgcg
     6421 cacctgcatt gatacggaca atccacaatt gacggaattg gcgtttgcgt tggcggcggt
     6481 cacggtatgc gtattgaccg gctttcatta ccgcctgctt ggcaacgcgg taaacgtttt
     6541 tacgacgacc gcgatagcct ttggctaacg cgaagatttt ttggtgacgg gcacgggcgg
     6601 taacaccgcg ttttacgcgt ggcatattct aaactcctta agcgtagggt aacattttag
     6661 caacagaagc caaatcgcga tcgtttacca tagaggtacc gcgcagttgg cgtttgtttt
     6721 tggtggtctt tttagtcaag atgtggcgtt tgaacgcatg agcgcgtttc acaccgccgt
     6781 tacccagtac tttaaagcgt tttttcgcgc tagacttggt tttcatttta ggcatgggaa
     6841 aactccattc gttatcggat aaggcattag ggggttttaa aacatcggtt tcaaacactt
     6901 gaacccacaa taccacggtt ttttgccgca attgaaaact tactccgaag cggcaatcgg
     6961 agtaagcgga gaattatagc tttatttttt cttcggcgca atcatcatta ccatttggcg
     7021 accttccatt ttgggaaagg actcgatttg cgccacttca gccaaatctt cttttacacg
     7081 ttccaaaagt tgcgcgccga gttgctggtg agccatttca cgaccgcgga aacgcaatgt
     7141 cactttgact ttatcgccgt cggcaaggaa gcggttgatg ttgcgcatct tgatttgata
     7201 atcgccctca tctgtacccg gacggaattt aatttccttg atttgtacct gcttttgatt
     7261 tttcttggct tcgtcgcgct tcttggcttg ttggtatttg tatttaccgt aatccatcag
     7321 tttgcataca ggcggtttag cagttgggga aatctctacc aaatcgacat cctgcccttc
     7381 ggccatagcc aaagcttcac gaactgaaac gacaccaagc tgttcgcctg actcactgat
     7441 taaacgcact tctttggcgg taatttcgcc gttgattcgt gcttcgcgtt cttgagcgat
     7501 gatgaatact cctataaaaa ttaatgattg acgagggcat cagtgatttc ttgctgcaat
     7561 tgcgcaatga aatcatccaa atccaaagaa cccaaatctt ctgctttgcg gcgtaccgcc
     7621 actttgtttt cctgcttctc cttatcgccg acaacgattt gataagggaa acggtattgg
     7681 ctgttgtcgc ggattttgta accgattttt tcgttacgca aatccaattc gacacggaat
     7741 cctgccgcct gcaatttggc agccacttcc cgacaataat ctgcctgatt ttcggtaata
     7801 ttcataatta ccaattgaac cggagccagc cataacggga aagagcctgc atagttctca
     7861 atcagaatgc cgataaatcg ctccaaagaa cctaaaatgg cgcgatgcaa cataacaggt
     7921 cgcgcacggt cattgttttc ggttacatat tctgcatcca agcgttccgg caagacgaaa
     7981 tccagttgta atgtaccgca ttgccaagaa cgacccaagg catctctgac atgatattcg
     8041 attttaggcc cgtaaaacgc accctcgccc ggcaattcgc cccattccac gccgcaggca
     8101 gtcaatgcct cgcgcaaacc ctgctctgcc ttatcccaca cgtcatctga acctgcacgt
     8161 tgttcagggc gaagagaaag cttgacggat acatcatgga aaccgaactg tttgtagatg
     8221 cgaaccaaca attcattgaa cgcacgggcc tcgctgacga tttgatcttc ggtacagaag
     8281 atatgcgcat catcttgcac aaaaccgcga acacgcatca gaccatgcaa tgcaccgctt
     8341 ggttcattgc ggtggcaaga accgaattcc gccaaacgca tcggcaaatc gcgatatgag
     8401 cgcaaaccgt tattaaaaat ttgcacatga cccggacagt tcatcggttt aaccgcatat
     8461 tcgcgttttt ccgaactggt tacgaacata ttgtctttat agttttccca gtggccggat
     8521 ttttcccaga aagttttatc cataatctga ggcgttttca cctctttata accggcagca
     8581 ttcaactctt tacgcatatg ctgttcaatc acttgccaca aagcccagcc tttaggatgc
     8641 caaaacacca tgcccggtgc ttcgtcttgc aaatggaaca gatccaattg cttgccaagt
     8701 ttgcggtggt cgcgcttttc ggcttcttcg atacgttgaa tataggcttt caactcgtct
     8761 tttgtcgccc aagccgtacc gtagatgcgt tgcagcattt cattgttgct gtcgccgcgc
     8821 cagtatgcgc ccgccagctt ggtcagtttg aagtttttca ggaaacgagt attcggaacg
     8881 tgcggtccgc ggcacatatc gacatattcc tgatgatgat acatccccat cgcttccact
     8941 tcggacatat cgtcaatcag gcgcagtttg tattcttcgc cgcgctcttg aaaaatttta
     9001 atcgcctccg cacgcggagt catgattttg accacatcat agtcttgggc aatcaattct
     9061 ttcatacgcg cttcaatggc ggcaacatct tccggtgtaa acggtttttc cgtggcgatg
     9121 tcgtaataaa agccctcttc aatgacgggg ccgataacca tttttgcatt aggatagagt
     9181 tgcttgacgg catgcccgac aagatgggcg caggaatggc ggatgatttc gatgccttcc
     9241 tgatctttcg gagtaatgat ttgaacagca gaattttcaa caatcgggtc gcacgcatcg
     9301 accaatttgc cgtttaccct gcctgccacc gtcgccttcg ccaaaccggc accgatagac
     9361 gcagcaattt gagccacggt aacgggggat tcgtattggc ggactgagcc gtccggcaag
     9421 gtaatattca acatcaaacg ctccgaaaga ttaaaaaata acggcataaa tgccgttatg
     9481 ggaatttggt aggcacgatt ggattcgaac caacgacccc caccatgtca aggtggtgct
     9541 ctaaccaact gagctacgtg ccttcaaaga atttttgcat tttatcgggt cgttttaatt
     9601 tttgcaagag gtatgtgcat ttctttatgc aacattgtgg caagatttgg ggatgtcgtc
     9661 tgaaaaaccg tgggaattca tttataatgc cgtcttttaa aacatatttc gatccctgtc
     9721 gcccaactga cattcaatct tatgcttaaa tttactttac acaaaaaaga cggatacgcc
     9781 cgacgcggca cgctggagtt gaaccacggc aaaatcgaaa cgccggtatt tatgcctgtc
     9841 ggtacttacg gctcggttaa ggcgatgaac ccgcaaaacc tgcacgacat caaggcgcaa
     9901 attattttgg gcaacactta tcatttgtgg ctgcgtccgg gcttggaggt cgtcgaacag
     9961 tttggagggc ttcacggctt tatcggctgg gacaaaccga ttttgaccga ctcgggcggt
    10021 tttcaggttt tttctttgtc ggatatgcgc aagctgacgg aagaaggctg tacgtttaaa
    10081 agcccgatta acggcgacaa gctgttttta tcgcctgaaa tttccatgaa aatccaaacg
    10141 gttttgaact cggacatcgc gatgcagttg gacgaatgca cgccgggcga ggcgacgcgc
    10201 gaacaggcgc gaaaatcgct gcaaatgagc ctgcgctggg cggaacggag caaaaaagcc
    10261 tttgaagatt tgaaaaaccc gaacgcgctg ttcggcatcg tgcaaggcgc gatgtatgag
    10321 gatttgcgcg aagaatcgct gcgcggtttg gaacagtttg attttcccgg ccttgccgtc
    10381 ggcggcttgt ccgtcggcga acccaagccc gaaatgtacc gtatgctgcg cgccgtcggt
    10441 ccgattctgc cggaacacaa gccgcattac ctgatgggcg taggcacgcc ggaagacctc
    10501 gtgtacggcg tggcacacgg catcgatatg ttcgactgcg tgatgcccac ccgcaatgca
    10561 cgcaacggct ggctgttcac ccgtttcggc gatttgaaaa tcaaaaacgc caaacacaag
    10621 ctcgacaagc gtccgataga cgaaagctgc acctgctacg cctgccaaaa cttcagccgc
    10681 gcctacctgc accatctgca ccgcgccggc gaaatcttgg gcgcacagct caacaccatc
    10741 cacaacctgc atttctacca agtcattatg gcggaaatgc gcgatgccat agaacaaggc
    10801 aaatttgccg actggcaggc acaattccac gaaaaccgcg cacgcggcac agactgattc
    10861 ccggcaatgc cgtctgaagc cgcttcagac ggcattttgc cgctttaccc tacccgcact
    10921 atttttcaga aaccgatcat gcttccattc tttccagaac cctccctttc ctatacgcaa
    10981 caaaaccgta ccgccgtttt gctgttgaac ctcggcacgc ccgacgcgcc gaccgcgcag
    11041 gcggtacgac cttatctgaa gtcctttctg accgaccggc gcatcgtcga actgcccaaa
    11101 tggctgtggt atcccattct gcatggtctg gtactgacgt tgcgccccaa aaaaagcgcg
    11161 cacgcctatg aaaaaatctg gtttaaggaa ggttcgcccc tagaagttta cacagcacgc
    11221 caagctgccg cgcttgccga acgtatgccc gacctcatcg tccgccacgc catgacctac
    11281 ggcaatcctt cggtggcaga cgtattgtcg gaactgaagg cgcaaggcgc gggcagactg
    11341 ctggtcatcc cgatgtaccc gcaatatgcc gcttccagca gcggagcggc agtagataag
    11401 gtgtgcgaac aattactgct gcaacggaac caaatgagcg tccgcaccgt ttcgcgcttt
    11461 tatgacgata ccggctacat tgatgcgatg aaaaaccaca tcctccgata ttgggcggaa
    11521 cacggacgtg ggaaaaaact gatgttgagt tttcacggcg taccgcagaa gcactacgac
    11581 ctcggcgacc cctatcccga cgagtgccgc cacaccgcca aactgcttgc cgaagcactg
    11641 gaactgaccg aagaccaata tgtcgtatcg ttccaaagcc aattcggcag ggcaaaatgg
    11701 gttacaccga gcacgcagga tttgttcggc aaactgccca aacagggggt aaccgagctg
    11761 gacgtattct gcccgggctt tttggcagac tgtttggaaa ccatggaaga aatcgccctg
    11821 atggggcggg aacagtttta cgaagcaggc ggcaaaagct accgctacat cccctgcctc
    11881 aacgacaacc ccgactggat agacgcactc gtcgcacttg ccgaagaaaa ccttggcggc
    11941 tggcgttgaa actgtttgac ccatgtctaa aatgccgtct gaacgccgtg ttcagacggc
    12001 attttcccgc tactttagcg tatgatggca tctatgccgg acaacaacat caagtgcaac
    12061 cttactaccg attcggcaaa aaaatctttc acccgctacg caaaatcaac aacaaggttt
    12121 caaacattaa ggaaacacca atgaacacaa cccgactgcc gaccgccctc gtcttgggct
    12181 gcctctgcgc cgccgcttct gccgccgaca acagcatcat gacaaaaggg caaaaagtgt
    12241 acgaatccaa ctgcgtcgcc tgccacggca aaaagggcga aggccgcgga accatgtttc
    12301 cgccgctcta ccgctccgac ttcatcatga aaaaaccgca ggtgctgctg cacagcatgg
    12361 tcaaaggcat caacggtaca atcaaagtca acggcaaaac ctacaacgga ttcatgcccg
    12421 caaccgccat cagcgatgcg gacattgccg ccgtcgccac ttatatcatg aacgcctttg
    12481 acaacggcgg cggaagcgtt accgaaaaag acgtaaaaca ggcaaaaggc aaaaaaaact
    12541 aaacagacaa aatgccgtct gaaaccggca atccggcttc agacggcatt caaatcaaac
    12601 ctttctaacg cggtactttc agccccatag acccgatatt gccgccaccg tcaacctcct
    12661 tcgcggtcag cataaagccg ccgatgtcaa tacggccgca ctcgaccggc tcctgactgt
    12721 cggaacgctt atcgaaaagc tcggcaaggc tcaaaccctc ttcgcccgct tccagcctca
    12781 aaccgtaagc aagtgccaaa tcacccgaac gtgctgccgg caaaacgaca aactcaccga
    12841 agaaatcaaa atactcacgg acgctaatac ccgtctcggt aaagtatttc gccattttat
    12901 agtgaactaa atttaaacca gtacg
//
LOCUS       DAXIDM010000050        12904 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000050 DAXIDM010000000
VERSION     DAXIDM010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12904
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.050"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            147..1199
                     /gene="bioB"
                     /locus_tag="ACFOAE_001229"
     CDS             147..1199
                     /gene="bioB"
                     /locus_tag="ACFOAE_001229"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004076 - biotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HFC6884710.1"
                     /translation="MTVSPVALRRKTECKPHPTARYWKKCDVEALFGLPFLELVHQAA
                     EVHRQNFNPREIQLSTLLSIKTGGCPEDCAYCPQSAHHNTNLGKEQMMDVDEIVEKAK
                     IAKSRGASRFCMGAAWRGPKPKDVETVSAIIKAVKGLGMETCGTFGMLEEGMAEDLKE
                     AGLDYYNHNLDTDPDRYNDIIHTRRHEDRMDTLGKVRNAGLKVCCGGIVGMNETRAER
                     AGLIASLANLDPQPESVPINRLVKVEGTPLADAEDLDWTEFVRTIAVARITMPQSYVR
                     LSAGRSNMPEAMQAMCFMAGANSIFYGDKLLTTGNPDEDGDRILMEKLNLYPLQFELE
                     GEVAKVEKASGIKVDY"
     gene            complement(1361..1927)
                     /locus_tag="ACFOAE_001230"
     CDS             complement(1361..1927)
                     /locus_tag="ACFOAE_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFC6884711.1"
                     /translation="MNIKYSGIENRFETAILKKNGVRYGFVSFAPNLAAVKLNDYAKV
                     KKLIAKTKQKAEIVIVMFHGGAEGKQAEHLPFDTEIFYGENRGNVVEFARLAVDSGAD
                     VVFGQGPHVTRAVELYRDRFISYSGGNFATYGAINTSGISGIAPIFKIITDKQGKFIS
                     GTIIPITQADDKIPKIDPEKPLSGGLFI"
     gene            complement(2051..2290)
                     /locus_tag="ACFOAE_001231"
     CDS             complement(2051..2290)
                     /locus_tag="ACFOAE_001231"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884712.1"
                     /translation="MGGCTFFRRTAFVKQRAFEVADGNVRVLQGRFDVFQNIGIGQVI
                     DRIIAAEHNVAHADNGNGIGCLFVRRILSVRIVGI"
     gene            2277..2510
                     /locus_tag="ACFOAE_001232"
     CDS             2277..2510
                     /locus_tag="ACFOAE_001232"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HFC6884713.1"
                     /translation="MQPPKICYAFRTPSAYGQYLADAGFDYLSFANNHSNDFGAQGIT
                     ATAASGSSFTYSIALKPLPITRPKLRKIPPSPR"
     gene            complement(2573..4432)
                     /gene="ilvD"
                     /locus_tag="ACFOAE_001233"
     CDS             complement(2573..4432)
                     /gene="ilvD"
                     /locus_tag="ACFOAE_001233"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HFC6884714.1"
                     /translation="MPDYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFT
                     QFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIAD
                     SIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQ
                     PERRLDLIDAMIESADDNISNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSL
                     PGNGSYLATHAGRKELFLEAGRMIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDI
                     AMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGG
                     IFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTHAIERFKAAPGGVRTTQ
                     AFSQNRMWKTLDLDREKGCIRDVEHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILK
                     FTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLG
                     KACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLAISDE
                     ELAARRAEMEARGSKAWKPKNRDRYVSAALRAYGAMATSADKGAVRDVAQIER"
     gene            complement(4605..6374)
                     /gene="cysI"
                     /locus_tag="ACFOAE_001234"
     CDS             complement(4605..6374)
                     /gene="cysI"
                     /locus_tag="ACFOAE_001234"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA];
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HFC6884715.1"
                     /translation="MTVQTKTKGLAWQEKPLSDNERLKTESNFLRGTILDDLKDPLTG
                     GFKGDNFQLIRFHGMYEQDDRDIRAERAEAKLEPLKFMLLRCRLPGGIIKPSQWIELD
                     KFARENSHYRSIRLTNRQTFQFHGVPKAKLQTMHRLLHKLGLDSIATAADMNRNVLCT
                     SNPIESELHRQAYEYAKKISEHLLPRTRGYLDVWVDGKKVQSSDDFLQEDEPILGKTY
                     LPRKFKTAVVIPPLNDVDCYGNDLDFVAISDGNGQLAGFNVLAGGGLSMEHGNTKTYP
                     NISLELGFVPPEHALKAAEAVVTTQRDFGNRSDRKNARTRYTIQNMGLDNFRAEVERR
                     MGMPFEPVRPFKFTGRGDRIGWVKGIDGNWHLTLFIESGRLVDEGGKQLLTGVLEIAK
                     IHKGDFRITANQNLIVANVPEGGKARIEQLARSYGLIHDGVSKLRENAMSCVSFPTCP
                     LAMAEAERVLPDFIGELDKIMAKHGTSDDYIVTRITGCPNGCGRAMLAEIGLVGKAVG
                     RYNLHIGGDREGVRIPRLYKENITLPEILSELDDLIGKWAAGRDTDEGFGDFAIRTGI
                     VKPVLDAPVDFWDASKAVPIARA"
     gene            complement(6401..8233)
                     /locus_tag="ACFOAE_001235"
     CDS             complement(6401..8233)
                     /locus_tag="ACFOAE_001235"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009337 - sulfite reductase complex
                     (NADPH) [Evidence IEA];
                     GO_function: GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="HFC6884716.1"
                     /translation="MSEHDMQNTNPPLPPLPPEITQLLSGLDAAQWAWLSGYAWAKAG
                     NGASAGNGASAGLPALQTALPAAEPFSVTVLSASQTGNAKSVADKAADSLEAAGIQVR
                     RAELKDYKAKNIADERRLLLVTSTQGEGEPPEEAVVLHKLLNGKKAPKLDKLQFAVLG
                     LGDSSYPNFCQAGKDFDRRFEELGAKRLLERVDADLDFTASADGWTGRIVARLKEEAA
                     KNRATPAPQTTPPAGLQTASEGRYCKADPFPAALLANQKITSRQSDKDVRHIEIDLSG
                     SDLHYLPGDALGVWFDNDPALVREILDLLGIDPATEIQAGGKTLPVASALLSHFELTQ
                     NTPAFVKGYAPFADDDELDRIAADNAVLQGFVQSTPIADVLHRFPAKLTAEQFAGLLR
                     PLAPRLYSISSSQAEVGDEVHLTVGAVRFEHEGRARVGGASGFLADRLEEDGTVRVFV
                     ERNDGFRLPEDSRKPIVMIGSGTGVAPFRAFVQQRAAENAEGKNWLIFGNPHFARDFL
                     YQTEWQQFAKDGFLHRYDFAWSRDQEEKIYVQDKIREQAEGLWQWLQEGAHIYVCGDA
                     AKMAKDVEAALLDVIIGAGHLDEEGAEEYLDMLREEKRYQRDVY"
     gene            complement(8230..9516)
                     /locus_tag="ACFOAE_001236"
     CDS             complement(8230..9516)
                     /locus_tag="ACFOAE_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit 1"
                     /protein_id="HFC6884717.1"
                     /translation="MTAQHQTPLRFITAGSVDDGKSTLIGRLLYDSKALLSDQIKTLE
                     SGKSKGLKEAIDFSILTDGLEAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRN
                     MVTGASTASAAVVLVDASQLDFGAQPLQLLPQTKRHSAILRQLDCPHIVVAVNKMDLL
                     DYSEDKFNAIVEAYRRLAGRLGLKDVHFVPVSALLGDNLVYPGGNMPWYRGEPLLAIL
                     ENLPGADETGRSAADFYFPVQLVVRQDADKADDFRGYQGRIERGSVAVGQTVRIEPNG
                     LTAEVSEIITPKGEVAQAFAGEAATLRLDRDIDVSRGDLFVDKNSPLAPQKHLEATLC
                     WFDERPLNTARKYLLKHGTQTVPAKVGEIESVLDVRTLEQEAGAESLKMNDIAKVRIN
                     LQKPVTATPYAENTAAGSFILIDEATYGTVAAGMIL"
     gene            complement(9555..10478)
                     /gene="cysD"
                     /locus_tag="ACFOAE_001237"
     CDS             complement(9555..10478)
                     /gene="cysD"
                     /locus_tag="ACFOAE_001237"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA];
                     GO_process: GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HFC6884718.1"
                     /translation="MTKTEPNNAQLDWLESESIHIIREVAAECENPALLFSGGKDSVV
                     LLALACKAFRLGSRPVKLPFPLVHIDTGHNYPEVIAFRDAQAAKLNARLIVGRVEDSI
                     AKGTVVLRKETDSRNAAQAVTLLETIEANGFDALMGGARRDEEKARAKERIFSFRDEF
                     GQWDPKAQRPELWSLYNTRLHKGENMRVFPISNWTELDIWQYIARENLELPPIYYSHR
                     REVVRRRGLLVPVTPLTPKMPSETSEILDVRFRTVGDISCTCPVESTASTPAEIIRET
                     AVADISERSATRLDDQASEAAMEKRKKEGYF"
     gene            complement(10516..11256)
                     /locus_tag="ACFOAE_001238"
     CDS             complement(10516..11256)
                     /locus_tag="ACFOAE_001238"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0004604 - phosphoadenylyl-sulfate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0019379 - sulfate assimilation,
                     phosphoadenylyl sulfate reduction by
                     phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenylyl-sulfate reductase"
                     /protein_id="HFC6884719.1"
                     /translation="METTLLKPALWQIPHIGSGSETALAEKTETLKQRLHRIAGSHRD
                     ARFASSLAAEDMVITDLIAGENLNIGIFTLDTGLLHAETLNLLDRIERVYPHMQIKRF
                     QPIREDALHYVESKGRFAFYDSVEARRECCRIRKIEPLNRAIAGADAWLTGQRREQSA
                     TRTELPFAEYDAGRGIGKYNPIFDWSEHDVWAYILANNVPYNDLYRQGFPSIGCDPCT
                     RPVKAGEDIRAGRWWWEGRNSKECGLHK"
     gene            complement(11267..12718)
                     /gene="cysG"
                     /locus_tag="ACFOAE_001239"
     CDS             complement(11267..12718)
                     /gene="cysG"
                     /locus_tag="ACFOAE_001239"
                     /EC_number="1.3.1.76"
                     /EC_number="2.1.1.107"
                     /EC_number="4.99.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0043115 - precorrin-2 dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0051266 - sirohydrochlorin ferrochelatase
                     activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="siroheme synthase CysG"
                     /protein_id="HFC6884720.1"
                     /translation="MNYFPIFANLAGRPVLVVGGGSVAARKISLLLDAGAQVRVVANQ
                     LNAELSALAAENKILWLAEEFRAEHIRTVFLIIAASSDQALNRRVFQLAESCQKPVNV
                     VDDRDYCSFIFPSIINRNPIQIAVSSSGSAPVLARLLRERLEALLPPSLGDMAEISGR
                     WRDAVKGKLKSVTERRRFWEKQFNGRFATLVKNRQNTLAERELAGQLEQSRQNDQGGS
                     VSLVGAGPGDAGLLTLKGLQEIQQADVVLYDALVSDGILSLVRRDAERIFVGKRARGD
                     RTPQEDTNALMVRLAREGRRVVRLKGGDPFVFGRGGEELETLARHQIPFSVVPGITAA
                     VGATAYAGIPLTHRDYAQSAVFVTGHRKADAPDIEWQTLARSRQTLVIYMGALKAALI
                     AERLQQHGRSPDTPAAVISQGTLPAQKTATGTLANLAELAETAPNPALIVIGEVVGLH
                     EKLAWFGENGEGENRVGQAYPALGGLNAGQRAA"
BASE COUNT         2506 a         3533 c         3776 g         3089 t
ORIGIN      
        1 cggaaaaacc gtttgccccg tattttcaaa cgcgttacac ttgccgccgc tgttttcagc
       61 catttgatta cccgcaaccg ccgtcattgc gccggcggtt tgcctgtcag cgtcattgcg
      121 ccgctgtaaa tacgaaagaa cacattatga ccgtatcccc cgtcgccttg cgccgtaaga
      181 ccgagtgcaa gcctcatccc accgcgcgct attggaaaaa atgcgatgtc gaggcacttt
      241 tcggactgcc gtttttagaa cttgtccatc aggcggcaga agtccaccgc caaaatttca
      301 acccgcgcga aatccagctt tccacgctgt tgtccatcaa aaccggcggt tgtcccgaag
      361 attgcgccta ctgtccgcaa tcggcgcacc acaacaccaa tctgggcaaa gagcagatga
      421 tggatgtgga tgaaatcgtc gaaaaagcca aaatcgccaa atcgcgcggc gcaagccggt
      481 tttgtatggg cgcggcatgg cgcggcccca aacccaaaga cgtggagacg gtttccgcaa
      541 tcatcaaagc cgtcaagggc ttgggtatgg aaacctgcgg cacgttcggt atgctcgaag
      601 aaggtatggc ggaagacttg aaagaggcgg gcttggatta ttacaaccac aacctcgaca
      661 ccgaccccga ccgctacaac gacatcatcc atacacgccg gcatgaagac cgtatggaca
      721 ccttgggcaa agtccgcaac gccggtttga aagtctgctg cggcggcatc gtcgggatga
      781 acgaaacccg cgccgaacgt gccgggctga ttgccagcct cgccaatctc gacccgcagc
      841 ccgaaagcgt accgattaac cggttggtca aagtggaagg tacgccgctt gccgatgccg
      901 aagatttgga ctggacggag tttgtccgca ccatcgccgt ggcgcggatt acgatgccgc
      961 aaagctacgt ccggctgtcg gcagggcgca gcaatatgcc ggaagcgatg caggcgatgt
     1021 gctttatggc gggcgcgaat tcgatttttt acggcgacaa gctgttgacc acaggcaatc
     1081 cggacgaaga cggcgacaga atcctgatgg aaaagcttaa cctgtatccc ttacagtttg
     1141 agctggaagg cgaggtcgcc aaagtggaaa aagcctctgg gattaaagtg gattattgac
     1201 gattgaaaaa tgccgtttga aacgcggatg ccgtctgaaa cccgaaaaaa ggctttcaga
     1261 cgacatttgt tcacggcatt tccaatatct ttttaccggc gcgtgatgct gccgtcgggc
     1321 gagacatcca gtccgttccc gttggggaag tcgctgcggt tcagataaat aatccgcccg
     1381 ataacggttt ttcagggtcg attttgggga ttttatcgtc ggcttgggta atcgggatga
     1441 tggttccgga aataaattta ccctgtttgt cggtgatgat tttgaaaatg ggggcgatgc
     1501 cgctgatgcc ggaggtgttg attgcgccgt aggtggcaaa attgccgccg ctgtaggaga
     1561 tgaagcggtc gcggtaaagt tcgacggcgc gtgtaacgtg cggcccctgc ccgaatacga
     1621 catccgcgcc ggaatcgacg gcaagccgcg caaactcaac gacgttgccc ctgttttccc
     1681 catagaagat ttcggtatcg aacggcaggt gttccgcctg tttcccttct gcgccgccgt
     1741 ggaacatcac aataacgatc tcggcttttt gtttggtttt ggcaatcagt tttttgactt
     1801 tggcatagtc gttcagtttg acggcggcaa ggttgggggc gaaggagacg aagccgtatc
     1861 ttacgccgtt tttcttcagg atggcggttt caaacctgtt ttcgatgccc gaatatttga
     1921 tgttcaattc gtcaaggttc gccctttatg ccgtttccgc accgcaaacc gccggggtca
     1981 agccctcggc gcatcctgcc ggaacggaat ccccgtgctg ccgattgacg gttcaaaccc
     2041 cgcgcccgtt tcaaataccg acgatgcgga cggacaggat gcgcctgacg aaaagacagc
     2101 cgataccgtt tccattatcg gcgtgggcga cattatgctc ggcagcaatt atccggtcga
     2161 ttacctgccc gataccaata ttctgaaaaa cgtcgaatct gccttgcaag acgcggacat
     2221 taccgtcggc aacctcgaag gcacgctgtt tgacgaaggc ggtacgccga aaaaatgtgc
     2281 aaccccccaa aatatgctat gcattccgaa cgccctccgc atacgggcaa taccttgccg
     2341 acgcgggatt cgactacctc agcttcgcca acaaccacag caacgacttc ggcgcgcaag
     2401 gcattacggc aacggcggcg agcggcagct cttttacata ctcgatcgcg ctaaagccgc
     2461 tgccgataac gaggccaaaa ttgcggaaaa taccgccatc gcccagataa atttgtccat
     2521 catcagacct ttactgttca gacgagacag catttgccgc acgttttggg gcttatcttt
     2581 cgatttgcgc tacgtcgcgc accgcgcctt tgtcggcgga agtcgccatc gcgccgtaag
     2641 ctcttaatgc ggcggagacg tagcggtcgc ggtttttagg cttccatgct ttgctgccgc
     2701 gcgcttccat ttcggcacgg cgtgcagcaa gctcttcatc ggaaatggca aggtggatgc
     2761 tgcggttggg gatgtcgatt tcgacggtat cgccttcgtg taccaaaccg atcgcgccac
     2821 cttccgccgc ttcgggcgag gcgtgtccga tggacaaacc tgatgtgccg ccggagaagc
     2881 gtccgtcggt taagagagcg caggctttgc cgaggccttt agatttcagg taggaagtcg
     2941 gatacagcat ttcctgcatg cccgggccgc ctttcgggcc ttcgtagcgg atgatgacga
     3001 tgtcgccggc gacgatttgg ttgcccaaaa tgccttctac tgcgtcttct tggctttcaa
     3061 acacgcgggc gcggccggta aatttgagga tgctctcgtc cacgcctgcg gtttttacca
     3121 cgcagccgcg ctcggcgata ttgccgaaca agaccgccaa accgccgtct tgcgagtagg
     3181 cgtgttccac gtcgcggata cagccttttt cgcggtcgag gtcgagggtt ttccacatac
     3241 ggttttgcga gaacgcttgg gtggtgcgta cgccgccggg cgcggctttg aagcgttcga
     3301 tggcgtgggt gttttcaggg ttggttacgt cccatttttc aatcgcgtct ttcagcgtcg
     3361 gcgcgtggat agtgtgcacg tcggtgtgca gcttgcccgc tttgtccaat tctttcagga
     3421 tggcgaaaat gccgccggcg cggtgcacgt cttccatata gtagtcgtgg ttgttgggtg
     3481 cggttttgca gatgcagggc acaacgcggc ttaagcggtc aatgtcggcc attttgaaat
     3541 cgacaccggc ttcgttggca acggccaaca ggtgcaaaat ggtattggtg ctgccgccca
     3601 tcgcaatatc catcgtcata gcgttttcaa acgctttttt ggtggcaatg ctgcgcggta
     3661 acacggtttc atcgttttgc tcgtaatagc gtttggtgat ttcgacaatc atacggccgg
     3721 cttcgaggaa caattctttg cggccggcgt gggtcgccaa atacgaaccg ttgccgggta
     3781 gggacagacc gagtgcttcg gtcaggcagt tcattgaatt tgccgtaaac atacccgaac
     3841 acgaaccgca ggtcgggcag gcgttttgtt cgacttcttc aacttgccgg ttgctgatat
     3901 tgtcgtccgc cgattcaatc atcgcgtcaa tcaagtccaa acggcgttcg ggttggatgt
     3961 ttgccacgcc gataacttta cctgcttcca tcgggccgcc ggaaacgaag atggtcggga
     4021 tattcagacg catcgcagca atcagcatgc ccggggtgat tttgtcgcag ttggaaatgc
     4081 acaccagcgc gtcggcgcag tgggcgttga ccatatattc gatggagtcg gcaatcaaat
     4141 cgcggctggg cagggagtag agcataccgc tgtgtcccat agcgatgccg tcgtcgatgg
     4201 cgatggtgtt gaattctttg gcgattgcgc cggctttttc gatctcgcgg gcaaccagtt
     4261 ggcccatatt gtgcaggtgg acgtggccgg gcacgaattg ggtgaaggag ttggcaacgg
     4321 cgatgatggg cttgccgaag tcggtttcca tcacgccggt ggcgcgccac aatgcgcgtg
     4381 cacccgccat attgcgaccg tgggtggagg ttttggagcg gtagtccggc atagtgtgtt
     4441 tccttgtctg ctatgccgtc tgaacggcaa aaggctttca gacggcattt ttgttgtgtt
     4501 ttgaaatgaa aaaaaaggta ttttatacca agtatcggaa ttttgcggaa tggaaacgcg
     4561 tgcggcaaaa aaggacatcc cccgcaggaa tgcgggggac ggtttcaggc gcgcgcaatc
     4621 gggacggctt tggatgcgtc ccaaaaatcg acgggcgcat ccaacacggg tttgacgatg
     4681 cccgtccgta tggcgaaatc gccgaaacct tcgtcggtat cgcgtcctgc cgcccatttg
     4741 ccgatcaggt cgtctaattc ggaaaggatt tccggcaggg taatgttttc tttgtagagg
     4801 cgggggatgc gtacgccttc gcggtcgccg ccgatgtgga ggttgtagcg tccgacggct
     4861 ttgccgacca gtccgatttc cgccaacatc gcccgtccgc agccgttcgg gcagccggta
     4921 atgcgggtaa cgatgtagtc gtccgacgtg ccgtgtttcg ccataatctt atccagctcg
     4981 ccgatgaagt ccggcagcac gcgttcggct tccgccattg ccagcgggca ggtcgggaag
     5041 gaaacgcacg acatcgcatt ttcgcgcagt ttgctgacac cgtcgtgtat cagcccgtat
     5101 gagcgggcga gctgttcgat ccgggctttg cctccttcgg gtacatttgc cacgatgagg
     5161 ttttggttgg cggtgatgcg gaagtcgcct ttgtggattt tggcgatttc caacacgccg
     5221 gtcagaagct gtttcccgcc ttcgtcaacc aaacgcccgc tttcgatgaa aagggtcaaa
     5281 tgccagttgc cgtctatgcc tttcacccag ccgatacggt cgccgcgccc ggtaaatttg
     5341 aacgggcgta cgggttcgaa cggcataccc atacggcgtt cgacttcggc gcggaagttg
     5401 tccaagccca tattttgaat ggtgtagcgg gtgcgggcgt ttttgcggtc gctgcggttg
     5461 ccgaagtcgc gctgcgtggt taccaccgct tcggcggcct tcagcgcgtg ttccggaggc
     5521 acgaaaccca gttccagtga aatgttcgga taggttttgg tgttgccgtg ttccatcgaa
     5581 agcccgccgc ccgccaaaac attgaatccg gcaagctgtc cgttgccgtc tgaaatggcg
     5641 acaaaatcca agtcgttgcc gtagcagtcc acatcattta agggcgggat gacgactgcg
     5701 gttttgaatt tgcgcggcag ataggttttg cccaaaatcg gctcgtcttc ttgaaggaag
     5761 tcgtcggaac tttgaacttt tttgccgtcc acccacacat ccagataacc gcgcgtgcgc
     5821 ggcagcaggt gttcggaaat ctttttcgcg tattcgtaag cctgccggtg cagttcggac
     5881 tcgatcgggt tggacgtgca aagcacgttg cggttcatat ccgccgccgt ggcgatggaa
     5941 tccaaaccca gtttgtgcaa gaggcggtgc atcgtctgca acttggcttt cggcacgccg
     6001 tgaaattgga aagtttgccg gttggtcagc cggatggagc ggtaatgact gttttcccgg
     6061 gcaaatttgt ccagttctat ccattgggac ggtttgatga tcccgcccgg cagccggcag
     6121 cgcaaaagca tgaatttcaa aggctcgagt tttgcctcgg cgcgttcggc gcggatgtcg
     6181 cggtcgtcct gctcatacat accgtggaag cggatgagtt ggaagttgtc gcctttgaag
     6241 ccgcccgtga gcgggtcttt caaatcgtcc aaaatcgtgc cgcgtaaaaa attgctttcg
     6301 gttttcagac gttcgttgtc ggatagcggt ttttcttgcc acgccaaacc ttttgtcttg
     6361 gtctgtacgg tcattttgtg ttcctcccga ttatatttaa tcaataaaca tcacgctgat
     6421 agcgtttttc ttcgcgcagc atatccaaat attcttctgc gccctcttcg tccaaatgtc
     6481 ctgccccgat aatcacatcc agcaaggcgg cttccacgtc ttttgccatt tttgccgcat
     6541 cgccgcacac atagatatgc gcgccttcct gcagccattg ccaaagtcct tccgcctgtt
     6601 cgcggatttt gtcctgcaca tagatttttt cttcctgatc gcgggaccag gcgaaatcgt
     6661 acctgtgcag gaaaccgtct ttggcaaact gctgccattc ggtttgatag agaaaatcac
     6721 gggcaaaatg cggattgccg aaaatcagcc agtttttgcc ttccgcattt tctgcggcac
     6781 gttgttggac gaaagcgcgg aacggtgcga cgccggtgcc cgagccgatc atcacaatcg
     6841 gcttgcggct gtcttcgggc agcctgaagc cgtcgttgcg ttccacaaac acgcgcaccg
     6901 tgccgtcctc ttccagccgg tcggcaagga aacccgatgc gccgcccacc ctggcgcgcc
     6961 cttcgtgttc aaaacgcacc gcgccgacgg tcaggtgcac ttcgtccccc acttccgcct
     7021 gcgacgagga aatcgaatac aggcgcggcg caagcgggcg aagcaggccg gcgaattgtt
     7081 ccgccgtcag ttttgccggg aagcggtgca gcacatcggc aatcggcgtg ctttgcacaa
     7141 agccttgcaa aacggcgttg tcggcagcaa tacggtcgag ttcgtcatca tcggcgaacg
     7201 gggcatagcc tttgacaaag gcgggggtgt tttgcgtgag ttcaaaatgg gataacagtg
     7261 cggaggcaac cggcagggtt tttccgcccg cctgtatttc cgttgccgga tcgatgccga
     7321 gcaggtctag gatttccctg accagtgccg gatcgttgtc aaaccaaacg ccgagcgcgt
     7381 cgcccgggag gtagtgcaaa tccgaaccgc tcaaatcgat ttcgatgtgg cgcacgtctt
     7441 tatcggattg gcgggaggtg attttctgat tggccagcag ggcggcggga aaggggtctg
     7501 ccttgcagta cctgccctcc gatgccgtct gaaggccagc ggggggcgtt gtctgcggcg
     7561 cgggcgttgc ccggtttttt gcggcttctt cttttaagcg cgcgacaatg cgacctgtcc
     7621 atccgtctgc ggaggcggta aagtccaaat ccgcatcaac gcgttcgagc aggcgtttcg
     7681 cccccaattc ttcaaaacgc cggtcgaaat ctttacctgc ctgacagaaa ttcggatagg
     7741 agctgtcgcc caagcccagt acggcaaatt ggagtttgtc caatttcggg gcttttttgc
     7801 cgttcagcag tttgtgcagc acgacggctt cttccggcgg ttcgccttcg ccctgggtgg
     7861 acgtaaccag cagcaggcgg cgttcgtcgg cgatgttttt cgccttatag tctttcagtt
     7921 cggcgcgcct gacttggatg ccggcggctt ccaggctgtc cgccgctttg tcggcaacgg
     7981 atttcgcatt gccggtttgc gaggcggaaa ggacggttac ggaaaaaggt tctgccgccg
     8041 gcaatgccgt ctgaagcgcg ggcagtcctg cagatgcccc gtttcctgca gatgccccgt
     8101 ttcctgcttt tgcccaagcg tagccggaca gccacgccca ttgtgccgcg tccagccccg
     8161 acaggagctg cgtgatttcg ggcggcagag gcggtaatgg cggatttgtg ttctgcatat
     8221 cgtgttcact cataaaatca tacctgccgc aacagtgccg tatgtcgctt cgtctatcag
     8281 gataaacgaa ccggcggcgg tgttttccgc ataaggcgtt gccgtaacgg gtttttgaag
     8341 gttgatgcgg actttggcga tgtcgttcat cttcaaggat tccgcgccgg cctcttgttc
     8401 cagcgtgcgg acatccaaaa cgctttcaat ttccccgact tttgccggca cggtttgcgt
     8461 accgtgcttg agcaggtatt tgcgcgcggt gttgagcgga cgttcgtcaa accagcaaag
     8521 cgtggcttct agatgttttt gcggggcgag cggggaattt ttatcgacaa aaaggtcgcc
     8581 gcgcgaaaca tcgatgtcgc gatccagccg gagggttgcc gcctcgccgg caaaagcctg
     8641 cgccacttcc cctttcggcg tgatgatttc ggacacttcg gcggtcagcc cgttcggttc
     8701 gatgcggacg gtttgcccga cggcgaccga accgcgttcg atgcgcccct gatagcctcg
     8761 gaaatcatcg gccttgtcgg catcttggcg gacgaccagt tggacgggga aataaaaatc
     8821 ggcagcggaa cgaccggttt cgtccgcccc cggcaggttt tccaagatgg ccagcagcgg
     8881 ttcgccccga taccacggca tattgccgcc ggggtaaacg aggttgtcgc ccaagagtgc
     8941 ggacaccggt acgaaatgca cgtctttcaa accgagccgt ccggcgagcc ggcggtatgc
     9001 ctccacaatg gcgttgaatt tgtcttcgct gtaatccagc aggtccattt tgttgaccgc
     9061 caccacaata tgcgggcagt cgagttggcg gaggatggcg gaatggcgtt tggtctgcgg
     9121 cagaagctgc aagggctgtg cgccgaaatc cagttgggat gcgtcaacca gcacgactgc
     9181 cgccgaagcg gtgcttgcgc ccgtaaccat attgcgcgtg tattgttcgt gccccggcgt
     9241 gtcggcgatg atgaatttcc gtttcgccgt ggaaaaatag cggtatgcca catcgatcgt
     9301 aatgccctgt tcgcgttcgg cttccagtcc gtcggtcagg atggagaagt ctatggcttc
     9361 tttcaaacct ttgcttttgc cggattccaa ggttttgatt tggtcggaca gcagggcttt
     9421 gctgtcgtag agcagtcgtc cgattagggt gcttttgccg tcatcgacgc tgccggcggt
     9481 aatgaagcgg agcggggtct ggtgttgtgc cgtcatattt tcttcctcat atctgcttaa
     9541 agggtttttg aaatttagaa atagccttct tttttgcgtt tttccattgc cgcctcgctt
     9601 gcctgatcgt ccagccgggt cgcgctgcgt tcggaaatgt cggcaaccgc cgtttccctg
     9661 ataatctccg ccggcgtgga cgcggtgctt tctaccgggc aggtgcagct gatgtcgccg
     9721 acggtgcgga agcggacatc aaggatttcg gaggtttcag acggcatttt cggggtgagc
     9781 ggcgttacgg ggaccagcag ccccctgcgt ctgaccactt cgcgcctgtg gctgtaataa
     9841 atcggcggca gctcgaggtt ttcgcgggcg atgtattgcc agatgtcgag ttccgtccag
     9901 ttggaaatcg ggaagacgcg catattttcg cctttgtgca gcctggtgtt gtacagcgac
     9961 cacagttcgg ggcgttgcgc cttcggatcc cattgtccga actcgtctcg gaacgagaaa
    10021 atccgttctt tggcgcgggc tttttcttcg tcgcgccgcg cgccgcccat cagcgcgtca
    10081 aagccgtttg cctcgatggt ttccaacagc gtaaccgcct gcgccgcatt gcgcgaatcg
    10141 gtttctttgc gtaagaccac cgtgccttta gcgatggagt cttccacgcg ccccactatc
    10201 aggcgggcat tgagttttgc cgcctgcgcg tcgcggaagg caatcacttc gggataattg
    10261 tgtcccgtgt cgatatgcac cagcgggaag ggcagtttta ccggcctgct gcccagccgg
    10321 aaggctttgc aggcgagggc gagcaggacc acggaatctt tgccgccgga aaagagcagg
    10381 gcggggtttt cgcattctgc cgccacttcg cggataatgt ggatggattc ggattccaac
    10441 cagtcgagtt gggcgttgtt cggttcggtt ttcgtcatac catattcctt atttcttctg
    10501 tctgatattt atgaattatt tgtgcagccc gcattctttg ctgtttctgc cttcccacca
    10561 ccaccgccct gcgcggatgt cttcgcccgc cttgacgggg cgggtgcagg ggtcgcagcc
    10621 tatgctggga aatccttgcc ggtacaaatc gttgtaaggc acattgttgg cgaggatgta
    10681 tgcccacacg tcgtgttccg accagtcgaa aatcgggttg tatttgccga tgccccgtcc
    10741 ggcatcgtat tcggcaaacg gcagttccgt gcgtgtggcg gattgttcgc ggcgttgccc
    10801 ggtaagccag gcgtccgcgc ctgcaatggc gcggttgagc ggttcgattt ttcggatgcg
    10861 gcagcattcg cggcgcgctt caacgctgtc gtaaaaggca aacctgcctt tgctttccac
    10921 ataatgcagg gcatcttccc gtatcggttg gaaacgcttg atttgcatat gcggataaac
    10981 acgttcaatc ctatccaaca ggtttaaagt ttccgcgtgc agcagccccg tatccaaagt
    11041 aaaaataccg atattgaggt tttctccggc gataaggtcg gtaattacca tatcttccgc
    11101 agcaaggctg ctggcaaacc gtgcatcccg gtggctgccg gcaatccggt gcaggcgttg
    11161 tttgagggtt tccgtttttt ccgcaagggc ggtttcgctg ccggatccga tatgcggtat
    11221 ctgccacagg gcgggtttga gcagtgtcgt ttccattttt cccgccttat gccgcccgtt
    11281 gtccggcatt cagtccgccc aatgcgggat acgcctgccc gacccggttt tctccttcgc
    11341 cgttttcacc gaaccaggcg agtttttcgt gcagccccac cacttcgcct atgacaatca
    11401 atgccggatt cggcgcggtt tcggcgagtt cggcaaggtt ggcgagcgtg ccggttgcgg
    11461 ttttttgagc cggcaacgtg ccttggctga tgacggctgc cggcgtgtcg ggcgagcgtc
    11521 cgtgctgttg cagccgttcg gcaatcaggg cggctttgag cgcacccata taaatcacca
    11581 aggtctggcg gctgcgggcg agggtctgcc attcgatgtc gggcgcatcc gccttgcggt
    11641 ggccggttac gaaaaccgca ctttgggcat aatcgcggtg cgtgagcggg atgccggcat
    11701 aggcggtcgc gccgacggcg gcggtaatgc cggggacgac cgaaaacgga atctgatggc
    11761 gtgccaaggt ttccaattct tcgccgccgc gtccgaacac gaaagggtct ccgcctttca
    11821 aacgcaccac gcgcctgcct tcgcgggcca gcctgaccat aagcgcattg gtgtcctctt
    11881 gcggggtgcg gtcgccccgg gcgcgcttgc cgacaaaaat ccgttccgca tcgcggcgga
    11941 cgagggacag tatgccgtct gaaaccagcg cgtcgtaaag caccacgtct gcctgctgga
    12001 tttcctgtag ccctttgagc gtcagcagcc ccgcatcgcc gggacccgcg ccgaccagcg
    12061 agacggagcc gccttgatca ttttgacgac tttgttccaa ttggcctgcc aattcccgtt
    12121 cggcaagggt gttttgccgg tttttgacga gggtggcgaa acgtccgtta aactgctttt
    12181 cccaaaagcg gcggcgttcg gtaacggatt tcagtttgcc cttgacggca tcgcgccacc
    12241 ttcctgaaat ttccgccata tcgcccaaag acggcggcag cagggcttcc agcctttcac
    12301 gcagcagtcg ggcgaggacg ggcgcgctgc ccgaactgga aacggcaatt tgaatcggat
    12361 tgcgattgat aatcgaagga aaaataaaac tgcaataatc gcgatcgtcc accacgttga
    12421 ccggtttttg gcagctttcg gcaagctgga aaacgcgccg gttgagggct tggtcgctgc
    12481 ttgccgcaat gatgaggaaa actgtgcgaa tgtgttcggc acgaaattct tcggcaagcc
    12541 acaggatttt gttttctgcc gccagtgcac ttaattcagc attcaactga tttgcaacaa
    12601 ctctgacttg tgcgccggca tccagcaaca agctgatttt gcgcgcggcg accgaaccgc
    12661 cgcctacgac caatacgggg cggccggcga ggttggcgaa aatggggaaa taattcactg
    12721 gcgaactcct ttgctgtttg cacgcacctt gtttccgata tgatgcgtcg cggtattttt
    12781 gtcggaatgc gggtcatttt agacaaaagg attttcccgg ttaaataata aaaaggcatt
    12841 tgttagaagc tgaaagctat atgagggcgg ctgcggatgc ggcggttttc cgttttatag
    12901 tgga
//
LOCUS       DAXIDM010000051        12897 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000051 DAXIDM010000000
VERSION     DAXIDM010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12897
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.051"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            85..1482
                     /gene="aspA"
                     /locus_tag="ACFOAE_001240"
     CDS             85..1482
                     /gene="aspA"
                     /locus_tag="ACFOAE_001240"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HFC6884721.1"
                     /translation="MTVRIEHDLLGDREIPAEVYWGIHTLRAIENFKISTQKISDVPQ
                     FVRSMVMVKKATAQANGELGAVKPEIAAAIEKACDEVLLNNRCLDQFPSDVYQGGAGT
                     SVNMNTNEVIANLALEALGYEKGRYDIVNPMDHVNASQSTNDAYPTGFRLAVYYSIGE
                     LLDKLVVLKNAFAAKAEEFKDVLKMGRTQLQDAVPMTTGQEFQSCQVLLEEEILNLDR
                     TRQLLLEVNLGATAIGTGVNTPKGYAELVVKKLSEVSGLPCKLTENLIEATSDCGAYV
                     MVHGALKRTAVKLSKICNDLRLLSSGPRAGLKEINLPELQAGSSIMPAKVNPVIPEVV
                     NQVCFKVIGNDTTITFAAEAGQLQLNVMEPVIAQCMFETISLLGNAALNLSEKCVKGI
                     TVNREICERYVFNSIGLVTYLNPYIGHHNGDLVGKICAQTGKGVREVVLERGLLSEEE
                     LNRILSPENLMNPHL"
     gene            complement(1554..2429)
                     /locus_tag="ACFOAE_001241"
     CDS             complement(1554..2429)
                     /locus_tag="ACFOAE_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA/RhaT family transporter"
                     /protein_id="HFC6884722.1"
                     /translation="MAYLLISIVFSVSVSILLKMARKKKIDIAQAVAVNYVVAVILTL
                     LVLKPDVGNIGAFLPTWWLFAALGVLLPSVFVIMGKSVEAAGIVKSDAAQRLSLFLPI
                     VAALTLFGEKLSEGKLIGLCLAFAALFCLLWKHSGGKKSGSAWRQAALLLGVWAGYGI
                     IDILFKQLAKSGTAFAGNLLVAFALAGVLMFACLFAKSVRWRVESVVGGILLGGLNFM
                     NIVTYITAHQMMKDNPTLVFAGMNIGVIVLGTLSGALFFKEKINTINTAGIVLALCSI
                     ACLFYWAEVKALFGI"
     gene            complement(2431..3153)
                     /locus_tag="ACFOAE_001242"
     CDS             complement(2431..3153)
                     /locus_tag="ACFOAE_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFC6884723.1"
                     /translation="MDKDLYAVLGVSPQAGADEIKRAYRKLAMKYHPDRNPGNPKAEE
                     KFKEIQRAYDTLSDLSKRMQYDASFRRHEERGRQEEAFRREQARREQFYREQMRREQA
                     FRQAFERQASRSCHTYEPSGGGSGRNYVLAAYILFGLGAIMLFMPIVGVIFAYMPIVG
                     VILAYMKRNSLDSIVYAAHTEYLIKTFWRTFWLYILGALTALLGIGVLIIIATNVWYF
                     YRIIAGFIRFNGGRAVAPEKWI"
     gene            complement(3176..3655)
                     /gene="ybaK"
                     /locus_tag="ACFOAE_001243"
     CDS             complement(3176..3655)
                     /gene="ybaK"
                     /locus_tag="ACFOAE_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFC6884724.1"
                     /translation="MSKHTYPITPAVRVLRENGIEFEPFTYAYEEHGGTAQFARLFGK
                     DEHLVIKTIVLQDENGKGLIVLMHGDKQISTRNLARHLGAKRIEPATPAQANKWTGYL
                     VGGTTPFGIRTKLDIYVEQSVMDLETIYINGGKRGFIIGIRPRDLNILNPKTIQAAV"
     gene            3730..4092
                     /locus_tag="ACFOAE_001244"
     CDS             3730..4092
                     /locus_tag="ACFOAE_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HFC6884725.1"
                     /translation="MDIRYFGTTPRYSEAVGANGLIFLSGMVPENGETAAEQTADVLA
                     QIDRWLAECGSDKAHVLDAVIYLRDMGDYAEMNGVWDAWVAAGRTPARACVEARLARP
                     EWRVEIKITAVKKDAATA"
     gene            4127..4990
                     /locus_tag="ACFOAE_001245"
     CDS             4127..4990
                     /locus_tag="ACFOAE_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate-binding protein YgfZ"
                     /protein_id="HFC6884726.1"
                     /translation="MKTLLPFFGVVRVSGEDRQTFLHGQLSNDINNLQTGQACYATYN
                     TPKGRVIANMIVVNRGGDLLLIMAQDLLEATVKRLRMFVLRAKAVFEILEDYAVDAEL
                     EASAEPLAAQEPSLVFTAECVSDGICTVVLPHRGILHIAPETALPPYDAAAENAWRLH
                     EIRSGYPWICAATKETAVAQMLNQHIIGGVHFKKGCYPGQEIIARAQYRGQVKRGLAV
                     LSGNSAAEAGILLAADGEEAGIVLDSVKDSENFTALAVIKFSAAQKTLSAPNGGSFKA
                     VRTFFKTEGAE"
     gene            5083..6042
                     /gene="ttcA"
                     /locus_tag="ACFOAE_001246"
     CDS             5083..6042
                     /gene="ttcA"
                     /locus_tag="ACFOAE_001246"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HFC6884727.1"
                     /translation="MSKKTKQELENNKLSKRLRHAVGDAINDFNMIEPGDKIMVCLSG
                     GKDSYALLDILRQLQASAPIDFQLVAVNLDQKQPGFPEEVLPTYLESIGVPYKIVEED
                     TYSTVKRVLDEGKTTCSLCSRLRRGILYRTAKELGCTKIALGHHRDDILATLFLNMFY
                     GGKLKAMPPKLVSDNGEHIVIRPLAYVKEKDLIKYAELKQFPIIPCNLCGSQPNLQRQ
                     VIGDMLRDWDKRFPGRIESMFSALQNVVPSHLADTELFDFAGLERGQTLKHGGDLAFD
                     SEKMPERFSDGSEEDESEIKIAPQKAERKVINILANKPKTCGA"
     gene            complement(6176..6730)
                     /locus_tag="ACFOAE_001247"
     CDS             complement(6176..6730)
                     /locus_tag="ACFOAE_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC6884728.1"
                     /translation="MKPKFKTVLTALLLAVSLPSMAATHVLMETDMGNIRLVLDESKA
                     PKTVANFVRYARKGFYDDTVFHRVIDGFVIQGGGFTEDLVQKATDKAVANESGNGLKN
                     TAGTIAMARTADPDSATSQFFINLADNDSLNYKNGQYGYTVFGRVESGMNTVSKIARV
                     KTATRGFYQNVPVQPVKIRRVVVE"
     gene            complement(6795..7721)
                     /locus_tag="ACFOAE_001248"
     CDS             complement(6795..7721)
                     /locus_tag="ACFOAE_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFC6884729.1"
                     /translation="MSEVKKTKVHLISGFLGTGKTTALKSLMAQKDPNEKWVIIVNEF
                     GEIGIDGAVLSDNGIPVAEIAGGCLCCTAGPQMGVTVQKMLRDAKPDRLMIEASGLAH
                     AASVIDELKAKPLDSLLEIGAVFTVVDPRQFINPDYAQQALYKDQIGICDILVASKTD
                     LCTPEQLAEFHDKAAKLFPPKAKVVEVQNAQLDIQWLDIPIIEKSRYRLKALPDNTMG
                     FQSQGFTFPAGRDFDGEKLTNFFNDLPKFTEGLVRAKGVFQVLGTWVWLNWVDGQWGA
                     NQVSWRRDSRFELIAKSFDADLIEQKLKDALE"
     gene            complement(7709..8185)
                     /locus_tag="ACFOAE_001249"
     CDS             complement(7709..8185)
                     /locus_tag="ACFOAE_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFC6884730.1"
                     /translation="MKTNFKQKIIEQARSEGLQVTALREQVLDIVLQQSGVIKAYNVL
                     SQMQQQSEGVLAPPTAYRALDFWAEQGVLHKVAAVNGYILCSHAQHECDDHCHDHEEA
                     EAHHSAFILVCTECGTADEQTLSHEWAALRAGVAESGFVLKEEHVVLTGICKKCQK"
     gene            complement(8256..8711)
                     /locus_tag="ACFOAE_001250"
     CDS             complement(8256..8711)
                     /locus_tag="ACFOAE_001250"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFC6884731.1"
                     /translation="MKKPKILFVCLGNICRSPMAEYILRRRAAEAGIPLEADSAGTSG
                     WHDGEDMHRETAKILKKHGIDASGFTSRKIRQSDAVAFDCIIAMDGKNLSELERTFGR
                     RSEKIFKLTDLIPESGYDHVPDPWYTGDFEETFRLADAGCRALLEKISK"
     gene            complement(8836..9951)
                     /locus_tag="ACFOAE_001251"
     CDS             complement(8836..9951)
                     /locus_tag="ACFOAE_001251"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFC6884732.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLEEKCLQVTGPFGQKEVMRYFQKEQLALFEVADLVGLGKIPLEKR
                     NPLQIQTRGIGELIRHLISQEIKEIYIGVGGTASNDGGIGIAAGLGYQFYDEDGNALP
                     ACGQSLLNLASVSTENRYKIPEDVHIRILADVVSPLCGHQGATYTFGKQKGLDSTMFE
                     AVDQAIQDFYEKVSPATLKLKGAGAGGGIAGGLCAFAQASIVSGIDTCLDLIDFDKKV
                     SDVDLVIVGEGRLDRQSLAGKAPIGVAKRTPVGVPVVAICGSLVEDLPSLPFENIQAA
                     FSILEKSEPLEDSLKNASLYLEHTASNIGHLLNMPKI"
     gene            complement(10065..11162)
                     /locus_tag="ACFOAE_001252"
     CDS             complement(10065..11162)
                     /locus_tag="ACFOAE_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFC6884733.1"
                     /translation="MNQTFTLPDTRPYPQNPIKNHLLLNAYQLAHNSSQASRKLSSGQ
                     LQTEIRGMLEQNHYINLSLALTMSPDAGTYAALLSSVNAVLDCEKEGEVQWFALPVVL
                     VSGCKKERAIEMKLPTEGLFACLQNYPHLRALTQETQWLPYLVHSSDLSAVAPDEWWR
                     AKQNTEAAAQHLRRFAPRPLLLPEGQSVHVVYALGFGSGKVQTALGQNLLQAGLPLMQ
                     VWQENLASEGVTLFANPLSPDSPVRALSDGSHTRQRMAMDVFAANAIRAVRMQSPRVG
                     VVAAAKAGGQILFGFNATDGAFEVVPQVFSWQLSFTDNIGVIQQNFLDLMAECRVEHV
                     YLLHNPLGEQESIPSYAEALKREGHNPFFSA"
     gene            complement(11244..12763)
                     /locus_tag="ACFOAE_001253"
                     /pseudo
     CDS             complement(11244..12763)
                     /locus_tag="ACFOAE_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219202.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase regulatory domain-containing
                     protein"
BASE COUNT         3133 a         3538 c         3140 g         3086 t
ORIGIN      
        1 gccggtatag tgttcgtcct gcggcggcat ctttccgatg gcgcattttt tcaatattaa
       61 ttatccgact tacaaaggta aaacatgact gtccgtatcg aacacgattt attgggcgac
      121 cgcgagattc ccgccgaagt gtattggggc atccacactc tgcgcgccat tgaaaacttt
      181 aaaatctcca cacaaaaaat ttccgacgtg ccgcagtttg tccgcagtat ggtgatggtg
      241 aaaaaagcaa ccgcgcaggc aaacggcgaa ttgggtgcag taaaacccga aatcgccgcc
      301 gccattgaaa aggcttgcga cgaagttctg ctgaacaacc gctgcctcga ccaattcccc
      361 tccgacgtgt atcagggcgg tgcgggtact tcggtcaata tgaacaccaa cgaagtcatc
      421 gccaacctcg cattggaagc cttgggctat gaaaaaggcc gctacgacat cgtcaatccg
      481 atggaccatg tcaacgccag ccaatcgacc aacgatgcct atcccacggg cttccgcctt
      541 gccgtgtatt acagtatcgg cgaattgctc gacaaactgg tcgttctgaa aaacgccttt
      601 gccgccaaag ccgaagaatt taaagacgtt ttgaaaatgg gccgcaccca gcttcaagat
      661 gccgtgccaa tgactacagg acaagaattc caatcttgcc aagtgttgtt ggaagaagaa
      721 atcctcaacc tcgaccgcac gcgccaactg cttttagaag tcaatttggg cgcaacggca
      781 atcggcacgg gcgtgaacac gcccaaaggc tacgccgaac tggtggtcaa aaaactctcc
      841 gaagtcagcg gcttgccttg caaactgacc gaaaacctga ttgaggcgac ctccgactgc
      901 ggcgcatatg tgatggtaca cggcgcattg aagcgcacgg cggtcaaact ctccaaaatc
      961 tgcaacgact tgcgcctgct ctcttccggc ccgcgtgccg gcttgaaaga aatcaacctg
     1021 cccgaattac aggccggttc ttccattatg cctgccaaag tcaatcccgt gattcccgaa
     1081 gtggtcaacc aagtctgctt caaagtcatc ggcaacgaca ccaccatcac ttttgcagcc
     1141 gaagcaggtc agttgcagct gaacgttatg gagccggtaa tcgcccaatg tatgtttgaa
     1201 accatttctc tcttgggcaa tgccgctctc aacctgtccg aaaaatgcgt caaaggcatt
     1261 acggtcaacc gcgaaatctg cgaacgttac gttttcaact ctatcggttt ggtgacttat
     1321 ctgaacccat acatcggcca ccacaatggc gacttggtcg gcaaaatttg cgcccaaacc
     1381 ggcaaaggcg tgcgcgaagt cgtactggag cgcggtttgt tgagtgaaga agagctcaac
     1441 cgcatcctct ctcccgagaa cctgatgaac ccccatctgt aacgttgcag acaaatgccg
     1501 tctgaagcag ggatgctgct tcagacggca ttttgttata tcaatcagcc ggattatatg
     1561 ccgaacagtg ccttgacctc cgcccaataa aacaggcagg cgatggaaca cagtgccaac
     1621 acgattcccg ccgtattgat tgtgttgatt ttttccttaa aaaacagtgc gcccgaaagc
     1681 gtccccaaaa caatcacgcc gatattcata ccggcaaaaa ccagcgtggg attgtccttc
     1741 atcatttggt gcgcggtgat gtaggttacg atgttcatga agttcaaacc gcccaagagt
     1801 atgccgccga ccacactctc aacgcgccat ctgaccgatt tggcaaacag gcaggcaaac
     1861 atcagcacac ctgccagcgc aaatgcaacc agcaggttgc ccgcaaatgc cgttccgctt
     1921 ttggcaagct gtttgaacag gatatcgata atgccgtaac ctgcccacac gcccagcagc
     1981 aatgccgcct gccgccacgc gcttcctgat tttttgccac cgctgtgttt ccaaagcagg
     2041 cagaacagtg cggcaaaggc gaggcacagc ccgatcagtt tgccttcgct gagtttttcg
     2101 ccaaacagcg tcaaagcggc aacaatcggc aaaaacagcg acaaacgctg cgccgcgtcg
     2161 gatttgacga taccggcggc ttccacggat ttacccatta tcacgaatac ggacggcagc
     2221 agcacgccca aagcggcaaa cagccaccac gtcggcaaaa atgcgccgat attgccgaca
     2281 tccggcttca ataccagcag ggtcagtatg accgcgacca cataattgac ggcgaccgcc
     2341 tgcgcgatgt cgattttttt cttccttgcc attttcagca aaatggaaac cgacacgctg
     2401 aacacgatgc tgattaacag gtaagccata ctatatccat ttctcgggtg caaccgccct
     2461 gccgccgttg aagcggataa agccggcgat gatgcggtag aaataccaga cgttcgttgc
     2521 aataataatc agcacgccga tacccaaaag ggcagtcagc gcacccaaaa tataaagcca
     2581 aaatgtgcgc caaaaggttt taatcaggta ttcggtatgt gcggcataga caatgctgtc
     2641 caaactgttc cgtttcatat aggcgagaat cacgccgact atgggcatat aggcgaaaat
     2701 cacgccgact atgggcatga acagcatgat tgcacccaaa ccgaacagga tgtaggcggc
     2761 gaggacatag ttgcgcccgc ttccgccgcc ggacggttcg taagtatggc acgaacgtga
     2821 tgcctgccgt tcaaacgcct gtctgaacgc ctgttcgcgg cgcatctgtt cgcggtaaaa
     2881 ctgctccctg cgcgcctgtt cgcggcggaa tgcctcttcc tgccgcccgc gttcctcatg
     2941 ccgtctgaag gacgcgtcgt attgcatccg tttcgacagg tcggaaagcg tatcgtaagc
     3001 ccgttggatt tctttgaact tttcttccgc cttcggattg cccggattgc ggtcgggatg
     3061 atatttcatc gccagcttgc ggtaggcgcg tttgatttcg tccgctcccg cctgcggcga
     3121 cacgcccaat acggcataca aatctttgtc catattgttc ctttatactt tcccgtcaaa
     3181 ccgccgcctg tattgttttc gggttcaaaa tatttaaatc tctgggacgg atgccgataa
     3241 tgaacccgcg ttttccgccg ttgatataga tggtttccaa atccatcacc gactgttcga
     3301 cgtaaatatc caactttgtc cggatgccga acggcgttgt gccgccgacc aaatagcccg
     3361 tccacttgtt tgcctgtgcg ggcgtagcgg gttcgatgcg tttcgcaccc aaatgccgag
     3421 ccagattgcg cgtggaaatc tgtttgtcgc cgtgcatcaa gacaatcagc cccttaccgt
     3481 tttcatcttg caaaacaatg gttttaatga ccaagtgttc gtctttgccg aatagtcggg
     3541 caaactgcgc cgtgccgccg tgttcctcat aggcataggt aaaaggttca aattcgatgc
     3601 cgttttcacg caaaacgcgc acggcaggtg ttatcggata agtgtgttta ctcatttttc
     3661 gtcatgcaaa acatggaaat cggtcaagcg caatgttacc atatatcccc tttatcgaag
     3721 gaaaccgata tggatatccg atatttcggc acaacgcccc gctattccga agccgtcggc
     3781 gcaaacggct tgattttcct ctccggcatg gttcccgaaa acggtgaaac ggctgccgaa
     3841 cagactgccg acgtgcttgc ccaaatcgac cgctggctgg cggaatgcgg ctcggacaaa
     3901 gcgcacgttt tggatgcggt catctatctg cgcgatatgg gcgactatgc ggaaatgaac
     3961 ggcgtgtggg acgcttgggt tgccgccggc agaacgcccg cccgcgcctg cgtggaagcg
     4021 cggctcgccc gtccggagtg gcgcgtcgaa atcaaaataa ccgccgtgaa gaaagatgcg
     4081 gcaaccgcat aaacagattt cctttatatt tcagagtacg caaatgatga aaaccttact
     4141 gccctttttc ggcgtggtac gcgtcagcgg cgaagaccgc caaaccttcc tgcacggaca
     4201 gctttccaac gacatcaata atcttcagac cgggcaggcg tgttatgcga cttacaacac
     4261 gcccaaaggc cgtgtcatcg ccaatatgat tgtcgtcaac cgaggcggcg atttgctgct
     4321 gattatggcg caagacttgc ttgaagcaac ggtcaaacgt ttgcggatgt ttgtgttgcg
     4381 tgccaaagcc gtttttgaaa tccttgaaga ttacgccgtc gacgcggaat tggaagcatc
     4441 cgccgaaccg cttgccgcgc aagaacccag tctcgtcttt accgccgaat gcgtttcaga
     4501 cggcatctgc accgtcgtcc tgccccatcg gggcattttg cacatcgccc ccgaaaccgc
     4561 cctgccgcct tatgatgccg ccgccgaaaa cgcgtggcgg ctgcacgaaa tccgtagcgg
     4621 ttatccgtgg atatgcgcgg ctaccaaaga aactgccgtt gcccaaatgc tcaaccagca
     4681 catcatcggc ggcgtacact tcaaaaaagg ctgctatccc ggtcaggaaa tcattgcccg
     4741 tgcccagtat cgcggtcagg tcaaacgcgg cttggcggta ttgtcgggaa attcggcagc
     4801 cgaagcaggc atcctgctgg cggcagacgg cgaagaagcc ggcatcgtgc ttgacagcgt
     4861 aaaagattcg gaaaacttta ccgcccttgc cgtgattaaa ttctccgccg cacaaaaaac
     4921 actgtccgcc ccaaacggcg gcagcttcaa agccgtccgc accttcttta aaaccgaagg
     4981 tgcggaataa gccgccgatg ccgtctgaag cacttcagac ggcattgccg ccccgccaat
     5041 cggttacaat gccgcctttc taattttcaa acccaaaccg ttatgtccaa aaaaaccaaa
     5101 caagaactcg aaaacaacaa actcagcaaa cgcctgcgcc acgccgtcgg cgacgcgatt
     5161 aacgatttca atatgatcga gccgggcgac aaaatcatgg tctgtctctc cggcggcaaa
     5221 gacagctacg ccctgttaga catcctgcgc cagctccaag ccagcgcgcc gattgatttc
     5281 caactggttg ccgtcaatct cgaccaaaag cagccgggct tccccgaaga agtattgccg
     5341 acctatctcg aaagcatcgg cgtgccgtac aaaatcgtcg aagaagacac ttattccacc
     5401 gtcaaacgcg tattagacga aggcaaaacg acttgttcgc tgtgcagccg cctgcgccgc
     5461 ggcatcctct accgcactgc aaaagaattg ggctgcacca aaatcgcctt gggacaccac
     5521 cgcgacgaca tcctcgccac cttgttttta aatatgtttt acggcggcaa actcaaagcc
     5581 atgccgccca agctggtgag cgacaacggc gaacacatcg tcatccgtcc gctggcgtat
     5641 gtaaaagaaa aagacttaat caaatacgcc gaattaaaac aattccccat catcccgtgc
     5701 aacctctgcg gctcgcaacc caacctgcaa cgccaagtca tcggcgatat gctgcgcgat
     5761 tgggacaaac gctttcccgg ccgcatcgaa tcgatgttct ccgccctgca aaacgtcgtc
     5821 ccttcccacc ttgccgatac cgaactcttc gactttgccg gattggaacg cggtcaaacc
     5881 ctgaaacacg gcggcgattt ggcgtttgac agcgaaaaaa tgcccgaacg tttttcagac
     5941 ggcagcgaag aagacgaaag cgaaatcaaa atcgcgccgc aaaaagccga acgcaaagtc
     6001 atcaacattc tggcgaacaa gccgaaaacc tgcggcgcgt aaccccccgc cgtcaaaaat
     6061 gccgtctgaa gcccgtttgg cgtttcagac ggcattttaa aatcccgaag cagacgcttt
     6121 tcaaccccaa acacctgctt tttccgtttc agctttctga aggtttcccg ttatattact
     6181 cgacaacaac gcgacggatt ttgacgggct gtacgggtac gttttgataa aagccgcgcg
     6241 tggcggtttt gacgcgggcg attttggaaa cggtgttcat gccgctttcg accctgccga
     6301 aaacggtata gccgtattgt ccgtttttgt agttgagtga atcattgtcc gccagattga
     6361 taaagaattg gctggtggcg gaatccggat cggccgtccg cgccatggcg atggtaccgg
     6421 cagtgttttt caagccgtta ccggattcgt tggcaacggc cttatcggtt gccttttgta
     6481 ccaagtcttc ggtaaatccg ccgccctgga taacgaaacc gtcgataacg cggtgaaaaa
     6541 cggtgtcgtc gtaaaagcct tttcgggcat agcgcacgaa attagcaacg gttttggggg
     6601 ctttggactc gtccaaaacc aaacggatat tgcccatatc ggtttccatc aaaacatggg
     6661 ttgccgccat agacggcagg gaaaccgcca aaagcagcgc ggttaaaacg gttttgaatt
     6721 tgggtttcat cccgtcctcc tcagaccttc agacggcatt ttcatttcat atgccgtctg
     6781 aaggcgcgtg aacgctattc caatgcgtct ttgagctttt gttcgattaa atccgcatca
     6841 aacgatttgg caatcaattc aaaacgcgaa tcgcgccgcc atgagacttg gttcgcgccc
     6901 cactgtccgt ctacccagtt gagccacacc cacgttccca atacttgaaa cacgcctttg
     6961 gcgcggacga gtccttctgt gaatttgggt aggtcgttga agaagttggt cagcttttcg
     7021 ccgtcaaaat cgcgtccggc ggggaatgtg aaaccttgcg actggaagcc catggtatta
     7081 tccggcaggg ctttgaggcg gtagcgtgat ttttcgatga tgggaatatc gagccattgg
     7141 atgtcgagtt gtgcgttttg gacttcgacc actttagcct tgggcgggaa cagttttgcc
     7201 gctttgtcgt gaaattcggc aagctgttcg ggggtgcata aatcggtttt gctggcgacc
     7261 aatatgtcgc agatgccgat ttggtcttta tacaacgcct gttgcgcgta atcggggttg
     7321 atgaactggc gcggatcgac gacggtaaag acggcgccga tttccaaaag gctgtccagc
     7381 ggtttggctt tgagttcgtc gatgacgctg gctgcgtgcg ccagtccgct tgcttcaatc
     7441 atcaggcggt cgggcttggc atcgcgcagc attttctgta cggttacgcc catttgcggg
     7501 ccggcggtac aacacaaaca gccgccggcg atttctgcca cagggatgcc gttgtcgctc
     7561 aataccgcgc cgtcaatacc gatttcgccg aactcgttga cgatgatgac ccatttttcg
     7621 ttcgggtctt tttgcgccat caggcttttg agcgcggtgg ttttgcctgt tcctagaaaa
     7681 cctgaaatca ggtggacttt ggtttttttc acttctgaca ttttttacaa atcccagtta
     7741 aaacaacgtg ttcttctttc agcacaaagc cgctttcggc aacgcctgcg cgcagtgccg
     7801 cccactcgtg gctgagggtt tgctcgtccg ccgtgccgca ttcggtgcag accaaaataa
     7861 acgcgctgtg gtgcgcttcg gcttcttcgt ggtcgtggca atggtcgtcg cactcgtgct
     7921 gcgcgtggct gcacaaaata tagccgttga ccgccgccac tttgtgcaaa acgccctgct
     7981 ccgcccaaaa atcaagggcg cggtaggcgg taggcggtgc aagcacgccc tcgctttgct
     8041 gctgcatctg cgacaagacg ttgtaggctt taatcacgcc gctttgctgc aagacaatat
     8101 ctaatacctg ctcgcgcaaa gcggttacct gcaagccttc gctgcgtgcc tgttcgataa
     8161 ttttctgttt gaaatttgtt ttcataaatt ctctgtttat gccgtctgaa caaccgatac
     8221 ggcaggaggc ggttttatat ttgtattcaa ttgctttatt tggaaatctt ttccaacaat
     8281 gcccgacagc ccgcatccgc aagcctgaag gtttcttcaa aatcgcccgt gtaccacgga
     8341 tcggggacat ggtcgtaacc gctttcgggt atcaggtcgg tcagcttgaa tattttttcc
     8401 gaccgcctgc cgaaggttct ttccaattcg gacaaattct tgccgtccat cgcgatgatg
     8461 cagtcaaacg ccaccgcatc gctttggcgg attttgcggc tggtaaagcc tgaagcatcg
     8521 ataccgtgtt ttttcaatat ctttgccgtc tcgcggtgca tatcttcgcc gtcgtgccag
     8581 cccgatgtcc ccgcgctgtc cgcttcaagg ggaatgcccg cttcggcggc gcggcggcgc
     8641 aaaatgtatt ccgccatcgg cgaacggcag atgttgccga ggcagacaaa aaggattttc
     8701 ggttttttca tatcccctcc ctgttccggc gcgatgccgt ctgaagcgga aaccctttca
     8761 gacgtcatcg gtcggttaat cgtaaccgca taaggcagaa ccagccaaaa catccatctg
     8821 gaagaaatgg tttggctaaa tcttaggcat atttaataag tgtccaatat tagaagccgt
     8881 atgctccaaa tagagactgg catttttcaa actatcttct aaaggttcac ttttctccaa
     8941 aatagaaaag gcagcttgga tattttcaaa tggcagggaa ggcaaatctt caacgagact
     9001 gccacaaata gcgacaacag gaactccgac aggggttctt tttgctacac caataggcgc
     9061 tttccctgct aaactttgac gatctagtct tccttcacca acgataacca agtcaacatc
     9121 tgacactttc ttatcaaagt caatcaagtc caggcaggtg tcaattccag atacgatact
     9181 tgcctgagca aaggcgcaca aaccaccagc gatgcctcca ccagctcctg ctcctttaag
     9241 ttttaatgtt gcaggggaga ctttttcata aaaatcttgt attgcctgat ctacggcctc
     9301 aaacatagta gaatccaacc ctttttgctt gccaaacgta taggtcgcac cttggtgtcc
     9361 acataaggga ctcacaacat ctgctaaaat acgaatgtga acatcttcag gaattttata
     9421 gcgattttct gttgaaacag aagctaggtt tagtaaggat tgaccgcaag cgggtaaggc
     9481 atttccatcc tcatcataaa attgataacc taaaccagca gcaatcccaa tacctccatc
     9541 attactggcc gtaccgccaa cgccaatata gatttcttta atttcttgac taatgaggtg
     9601 gcgaatcaat tctccaatac cacgagtttg gatttgtaat ggatttcgtt tctctagcgg
     9661 gatttttcca agaccaacca aatcagcaac ttcgaatagg gctagttgtt ctttttgaaa
     9721 atagcgcatg acttcttttt gtccaaaagg tcctgtcact tggagacatt tttcttctag
     9781 gtcaagagaa tgtcggatag catctacagt gccttctccc ccatcaccga caggacagag
     9841 gagacattcc acatctgcta tcgattgttg gaagcctctt tttattgctt cagctacctg
     9901 ttgagctgtc aagctttcct taaacgaatc cggtgcaatt acaatcttca tatttataat
     9961 tcatcctttc gtttcactca aggcacaaca cagaatgaaa aagtgttgtg ctctttattt
    10021 tgatttatta tagaaatgag aaagcctatc actactacaa atcactatgc gctgaaaaac
    10081 ggattgtgcc cttcccgttt caatgcttcc gcatagctcg ggatgctttc ctgttcgccc
    10141 aagggattgt gcaacaggta aacgtgttct acacggcatt ctgccattaa atccaaaaaa
    10201 ttttgctgaa taacgccaat attgtcggta aaggaaagct gccacgaaaa cacctgcggc
    10261 acgacttcaa acgcgccgtc ggtcgcatta aacccgaata aaatctgtcc gcccgccttt
    10321 gccgctgcga ccacgccgac gcgcggactc tgcatacgga cggcgcgtat cgcgtttgcc
    10381 gcaaacacat ccatcgccat gcgctggcgc gtgtggctgc cgtcggaaag cgcgcgtacc
    10441 ggagaatccg gggaaagcgg attggcaaac agcgtaacgc cttccgatgc aagattttcc
    10501 tgccatacct gcatcaaggg cagacctgcc tgaagaaggt tctgacccaa tgccgtctga
    10561 actttgccgc tgccgaaacc cagcgcgtaa acgacgtgga cggactgccc ttcgggcaaa
    10621 agcaaagggc gcggggcgaa acggcgtaag tgttgcgccg ccgcttcggt attttgtttg
    10681 gcacgccacc actcatccgg cgcgaccgca ctcaaatcgg aggaatgtac aagataaggc
    10741 agccattgcg tctcttgcgt caacgcgcgc aggtgcggat agttttgcaa acaggcaaac
    10801 aatccctccg tcggcagctt catctcgatt gcccgttctt tcttgcagcc ggacaccagc
    10861 acgaccggca gggcgaacca ctgcacttcg ccttctttct cgcaatcgag taccgcgttc
    10921 acactggaaa gcagcgcggc ataagttccg gcatcgggcg acatcgtcag cgcgagggaa
    10981 aggttgatat agtggttttg ctcaagcatc cccctgattt cggtttgaag ttggccggac
    11041 gagagtttgc gcgaagcctg ggaagaatta tgcgccaact ggtaggcatt gagcagcagg
    11101 tggtttttaa tcggattttg gggatacggg cgcgtatcgg gcaaggtaaa tgtctggttc
    11161 atatatgtcg tgtaccgctt ttcgcagtgt gtgtttttcc tgtttgaaaa tatatcggac
    11221 ggattgccgt cgggacttgc ccgtcaatcc gccgaaacga gaaaatgcct gtctgccaag
    11281 tctgccaata tttcttccac atacacttcg gcaggcggat ggaatgtcaa accgtcgggc
    11341 gtggtgctga cgatgttcaa gttttcggca accgtttcaa tcaatgcctg tttgctcgtc
    11401 ggccgcgaca attgccgcat aatgtacaaa tgcccgtacc cgaatgaggg ggtgctttcg
    11461 ttgtaacggt tggcaggctg gacaaacgct tccgcgccgt gttccacaaa ggcggcgaca
    11521 taatctgtaa aacgcgccgg cacataggtt ttatggtctt caaaaaattg tttgcccgca
    11581 ttgtctgatg aaacagaaaa acgcccgaga atggtttgca ataaaagctg ggaattgatt
    11641 ttcatacggt cgaatgtcaa accgggaaat cggcgggcga gattttccgc aacatcttcc
    11701 gttttaaacg cctctccggt tttcatcaca tcgcgtatgc ccgaaagcag ggtatcgttt
    11761 tcatcaaagt tgattgtttc ccctcttgcc gggcggaaat tcaaactttc tatcacttcg
    11821 acggcaaccg actcgtcacg cctgacagta tccccgactt cctcacggca taaaagcgaa
    11881 cggcggaatt ggcggtcgga taaaatatcg ctgtaaaatt ctttggcaat ataatcgccc
    11941 cctgccaatg ccagaatccg ctcccgcgta tgctccgcca tccaagaaac aaaagacgcg
    12001 tgcaaatcgg tatccccgat atacgccagc cggtggcggt ttgcccattc gatgaagccg
    12061 ttaacgtaaa tcgggtcgtt gaatatttcc atatattcgt gtgcgacata ataagtattg
    12121 tgattcaata ttttttgaat cgccggaagt ttgccgccgc cgcccaagcc tttgtcgttt
    12181 tccaaaattt ccgccagcgc cttgagcgcg tccaagcctt tccgcgtccg cgcttccacc
    12241 agccagggta aacattgtat gaaatatagg caatgccgtg tttggtcagg ttgttccggc
    12301 aaatcgaaaa gattttgtct ttaaccgtat cgggaaccca cgaccaaata ccgtggacga
    12361 tgatatagtc gaacttcccg aatgactcat cgatggtcaa aatatctttt tcttccagac
    12421 gcacattttc caagcccatt ctttcaatga tggcgttgcc ctgcgcaacc tgcctgccgg
    12481 acaagtcgat accgacaaat tccgcatccg ggtaataaag cgcctgcgtg atgatgttgc
    12541 cgcccatcga acagcccagc tccaagacct tggcattggc ggcgggcgcg ggctgcaagc
    12601 ccatcaggcg ggcgcgcgcc tccaaattat tgatggcggt ttgagagaat gcgccggatt
    12661 cgtacatcaa atcatcatat gaatttttga tgttggacac gtccggcaca ccgttctccg
    12721 ttgcagcacg ggcaaaagcg gcttttttct tcttgctcga catattttgt tcactctaaa
    12781 gacaatatgc ccgcaagttt aaccaattca tcctacccgt tcaactaaat caaatgccat
    12841 ctgaaggcgc ggagcgtact tcagacggca tctaggaggc gcgaaggctt cagacgg
//
LOCUS       DAXIDM010000052        12780 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000052 DAXIDM010000000
VERSION     DAXIDM010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12780
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.052"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(617..1387)
                     /gene="xth"
                     /locus_tag="ACFOAE_001254"
     CDS             complement(617..1387)
                     /gene="xth"
                     /locus_tag="ACFOAE_001254"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008311 - double-stranded DNA 3'-5' DNA
                     exonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFC6884734.1"
                     /translation="MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPA
                     AALQMMGWHCVWSGQKTYNGVAIVSRNAPEDVHIGLPALPDDPQRRVIAATVGGVRVI
                     NVYCVNGEALDSPKFKYKEQWFAALTEFVRDEMTRYGKLVLLGDFNIAPADADCYDPE
                     KWHEKIHCSSVERQWFKNLLDLGLTDSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDH
                     ILVSPAMAEALKDVRVDLETRALERPSDHAPVTAEFDW"
     gene            complement(1447..1728)
                     /locus_tag="ACFOAE_001255"
     CDS             complement(1447..1728)
                     /locus_tag="ACFOAE_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFC6884735.1"
                     /translation="MNTIPLHTILKLMAHPERMAILLQLLDGDCNIAELSESLPMPAT
                     AVSNHLNRLRAGGLVDFTRYHRIIEYRLISEDAAAILRTIRDLENKRAV"
     gene            1785..2072
                     /locus_tag="ACFOAE_001256"
     CDS             1785..2072
                     /locus_tag="ACFOAE_001256"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884736.1"
                     /translation="MIVIIFINLIINQIFMDDCTGLYVPFPTFFANTRKGGLSDSIKL
                     PRPSFPLPCRCLRAVGQTKYLPETLFFLKHHDLHEKCRLKNISDGISSLRQ"
     gene            complement(2134..3015)
                     /gene="nadC"
                     /locus_tag="ACFOAE_001257"
     CDS             complement(2134..3015)
                     /gene="nadC"
                     /locus_tag="ACFOAE_001257"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HFC6884737.1"
                     /translation="MPSENTLFPLPDPLLRPMVEQALSEDLGRRGDITSAAVIAPDKT
                     AKLFLVSREDGVIAGMDLARLAFQTMDPSVRFQAEIRDGQVVRAGQTLAAVEGNARAL
                     LAAERTALNYLTHLSGISTATARAVAEVAKYGTDIVCSRKTIPLLRVLQKYAVRAGGG
                     VNHRMGLDDAVLIKDNHLAYCGSIAQAVRQAKQAVGALTCVEIEVDTLAQLDEAIAAG
                     AERILLDNMDDETLKEAANRCHTQTAHPHTVYCEASGGIGFDRLKRVAQTGVDGIALG
                     YLTHSSRSLDIGLDFLA"
     gene            complement(3090..4028)
                     /locus_tag="ACFOAE_001258"
     CDS             complement(3090..4028)
                     /locus_tag="ACFOAE_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884738.1"
                     /translation="MDAYPEAEAPPQSIVELVPVLIAVTDGGLRVLTVAQGTLLPNGP
                     LSPLRNSLQAGVKLWVAKQTSQPMGYVEQLYTFVDTHRRNEHGMPVLYVSYLGLVREA
                     ADSILHPDAKWQDCYGYFPWEDLRTDGGQRDAVVSRLRIWANSADTEEVRQMRLKRIH
                     LCWGVEPENWSEEYVLQRYEMLYESGLIVEAAEPQANFDFALTGQPMRHDHRRVLATA
                     LSRLRAKIKYRPVIFELMPPEFTLLQLQNSVEAISGRLLHKQNFRRQIQQQNLIEPSD
                     TGVSGSKGRPAQLCRFRDDVLPDRLISDIGLPLGSR"
     gene            4335..5447
                     /gene="nadA"
                     /locus_tag="ACFOAE_001259"
     CDS             4335..5447
                     /gene="nadA"
                     /locus_tag="ACFOAE_001259"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008987 - quinolinate synthetase A
                     activity [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HFC6884739.1"
                     /translation="MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETAGRL
                     KDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEASTLVVAG
                     VRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAA
                     VKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVH
                     NEFKGQELAALKAEHPEAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSHPEKKFIVA
                     TDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSLGGIKYALTSGHNEI
                     LLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGLA"
     gene            5501..7009
                     /gene="nadB"
                     /locus_tag="ACFOAE_001260"
     CDS             5501..7009
                     /gene="nadB"
                     /locus_tag="ACFOAE_001260"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008734 - L-aspartate oxidase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HFC6884740.1"
                     /translation="MQTDCDVLIAGNGLAALTLALSLPESFRIVILCKNRLDDTASRH
                     AQGGIAAAWSGEDDIEKHVADTLEAGAGLCDEAAVRAILSQGKPAIEWLLAQGVAFDR
                     NHNDLHLTREGGHTCRRIAHVADYTGEAVMQSLLAQIRRRPHIRVCERQMALDIQTES
                     GVACGLIVLDRRTQETYLIRARHTVLAGGGLGQIYAATTTPPECTGDAIAMAIRAGCA
                     VENLEFIQFHPTGLARSSENGRTFLISEAVRGEGGILTNQAGERFMPYYDRRAELAPR
                     DIVARAIAAEIAKQTQDFVSLDISHQPAAFVRRHFPSIHRHCLSQCGLDITRQAIPVR
                     PVQHYTCGGIQTDPCGRTSLPQLYSLGETACTGLHGANRLASNSLLECVVTARLAAQT
                     IADGQAFQAKTSPRPSESLSSEAGIFSDGIQSAFSRPVLQAFNQRHLGILRNDTGLRC
                     AIAQLRLWKQNQTEPHTASEYENRNLLECSLAVAQAAYRRRQNIGAHFNSDC"
     gene            complement(7173..7838)
                     /gene="pgmB"
                     /locus_tag="ACFOAE_001261"
     CDS             complement(7173..7838)
                     /gene="pgmB"
                     /locus_tag="ACFOAE_001261"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFC6884741.1"
                     /translation="MTFTAVLFDLDGVITDTAEYHYRAWKKLATELGISIDRKFNEQL
                     KGVSRDDSLKRILAHGGKTVSEAEFAELTRRKNDNYVEMIQAVKPEDVYPGILPLLEA
                     LRANGKKIALASASKNGPFLLERMGLTHFFDAIADPAAVAHSKPAPDIFLAAAEGVDA
                     DIRQCIGIEDAVAGVAAIKAAGALPIGVGKAEDLGSDIALVSDTAELTYAYLQNVWAQ
                     SGR"
     gene            complement(7851..10109)
                     /locus_tag="ACFOAE_001262"
     CDS             complement(7851..10109)
                     /locus_tag="ACFOAE_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFC6884742.1"
                     /translation="MYTRIMEISPWTLRSAKLEKEHKRLQESLTSLGNGYMGMRGSFE
                     ETYSADSHLGTYIAGVWFPDKTRVGWWKNGYPKYFGKAINALNFSKVKIFVDGQEVDL
                     AKNDVAGFSVELDMQHGVLRRSFTVFGVRFDVCKFLSVAQKELAVIRWEAVSVDGKTH
                     QVRIDSIIDADVKNEDSNYEEKFWQVLDKGVSDSLSYIAAQTVANPFGVEQFIVNAEQ
                     TFAGSFKALGGSQTDWQVSNSFESEVGGTPKTFEKRVIVTTSRDYQGLEAVKAAGRAL
                     SEKVAGVAFETLLDAHKAGWLHRWEIADVVIEGSDEAQQGIRFNLFQLFSTYYGEDAR
                     LNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAEPEVTRNLLQYRRNQLPQAQHNARE
                     QGLAGALYPMVTFTGIECHNEWEITFEEIHRNGAIPYAIYNYTNYTGDESYLAKEGLE
                     VLVEVSRFWADRVHFSKRSGKYMIHGVTGPNEYENNINNNWYTNTLAAWVLDYTREAL
                     AKYPRPDLNVSAAELEKWADISANMYRPHDEELGVFVQHDGFLDKDIRPVSALSPDDL
                     PLNQKWSWDKILRSPFIKQADVLQGIYFFGDRFNIDEKRRNFDFYEPMTVHESSLSPC
                     IHSILAAELGKEEKAVEMYRRTARLDLDNYNNDTEDGLHITSMTGSWLAIVQGFAQMK
                     TWGGKLSFAPFLPSAWTGYTFHINYRGRLIKVAVGKENVVFTLLKGEPLDLQVYGKDI
                     TLNGSHTVALEK"
     gene            complement(10343..11353)
                     /locus_tag="ACFOAE_001263"
     CDS             complement(10343..11353)
                     /locus_tag="ACFOAE_001263"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFC6884743.1"
                     /translation="MSDTPATRDFGLIDGRAVTGYVLSNRRGTRVCVLDLGGIVQEFS
                     VLADGVRENLVVSFDDAASYADNPFQINKQIGRVAGRIRGAAFDINGRTYRVEANEGR
                     NALHGGSHGLAVTRFNAVAADGRSVVLRSRLQQSADGYPNDLDLDISYRLDEDDRLTV
                     SYRATALGDTVFDPTLHIYWRLDAGLHDAVLHIPQGGHIPADAEKLPVSTVSDDLEVF
                     DFSRPKPLDAAVAALRRETGRAGFDDAYRVPSDIGRPAAVLQAGRRRRISIYSDRNGL
                     VIFTAAPQDFARHDAGVYDALATEAQTLPDSLHWPEFGNIRLNKGDTREATIAYGIES
                     LS"
     gene            complement(11357..12712)
                     /locus_tag="ACFOAE_001264"
     CDS             complement(11357..12712)
                     /locus_tag="ACFOAE_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC45 family MFS transporter"
                     /protein_id="HFC6884744.1"
                     /translation="MSEYTPQTAKQGLPALAKSTIWMLSFGFLGVQTAFTLQSSQMSR
                     IFQTLGADPHNLGWFFILPPLAGMLVQPIVGHYSDRTWKPRLGGRRLPYLLYGTLIAV
                     IVMILMPNSGSFGFGYASLAALSFGALMIALLDVSSNMAMQPFKMMVGDMVNEEQKGY
                     AYGIQSFLANTGAVVAAILPFVFAYIGLANTAEKGVVPQTVVVAFYVGAALLIITSAF
                     TIFKVKEYDPETYARYHGIDVAANQEKANWFELLKTAPKAFWTVTLVQFFCWFAFQYM
                     WTYSAGAIAENVWHTTDASSVGYQEAGNWYGVLAAVQSVAAVICSFVLAKVPNKYHKA
                     GYFGCLALGALGFFSVFFIGNQYALVLSYTLIGIAWAGIITYPLTIVTNALSGKHMGT
                     YLGLFNGSICMPQIVASLLSFVLFPMMGGLQANMFLVGGVVLLLGAFSVFLIKETHGG
                     V"
BASE COUNT         2802 a         3515 c         3593 g         2870 t
ORIGIN      
        1 aacatcgcta gagatgggcg actttgattt tccatttatt gattagtaaa ggatataaat
       61 actaacttgc cattgtcaaa ccacatagat ttatatagtg gattaaattt aaaccagtac
      121 gtcgttgcct cgccttgccg tactatttgt actgtctgcg gcttcgtcgc cttgtcctga
      181 tttttgttaa tccactatag ttattgcctt tgggagaatc aattctgaca gcacataaca
      241 taggttcatc tttacagtcg ttatattggg tttcatcaaa ctcaactgca tagcacaata
      301 aaggcaatag gaaaaaaagg agattaattt attactatac ataaggcagc ctgattattc
      361 attctaaaat aaatccggtt tttaatattt gattctgctc cggattatat acataataaa
      421 ttttactgct ccaaaatctg atattaaccc tatggatttc ataaattttt cagaaaaata
      481 ggctgtgctt gaacaatccg ccgactccgg ctgtttgtca gggaaaaggc aattattttc
      541 ggttagtcag cagcctatcc tattgaatca cttaaagata tggatgtttg tcaacgccat
      601 atcaaaacac ggtcttttac caatcgaatt ctgccgtcac cggcgcgtgg tcgctcggac
      661 gctccagcgc gcgcgtctcc aaatcgacac ggacatcctt caacgcctcc gccatcgcag
      721 gcgacaccaa aatatggtcg atacgcaggc ccagtttgcg ttggaacatc gcgccgcgat
      781 agtcgaacca ggtatagaac gcgccttcgg gatggacttg gcgcaggctg tcggtcagtc
      841 ccaaatccag caggtttttg aaccactgcc gttcgacgga cgaacagtgg attttttcgt
      901 gccatttttc agggtcgtaa cagtccgcat cggcaggcgc gatattgaaa tcgcccagta
      961 gcaccagttt gccgtagcgg gtcatttcat cgcggacaaa ttcggttaac gcggcaaacc
     1021 attgttcttt atatttgaat ttcgggctgt cgagggcttc gccgttgacg caatagacat
     1081 tgatgacgcg cacaccgccg acggttgccg caatcacgcg ccgttgcgga tcgtccggca
     1141 gcgcgggcag cccgatatgc acgtcttccg gcgcgttgcg gctgacgatt gccacgccgt
     1201 tgtaggtttt ctgcccgctc caaacacagt gccagcccat catctgcaag gcggcagccg
     1261 gaaatttgtc ctgatcgagt ttgagttcct gcaaaaccaa aatatcgggc ggattgtcgg
     1321 caagcaggtt ttgcacctgc ggcagccgca cattgagcga attgacgttc caagtggtga
     1381 ttttcataac atttccgaaa aatgccgtct gaaacgttca gacggcaaaa ggaaaggatt
     1441 ttaacactat accgcgcgtt tgttttccaa atcgcggatt gtccgcagaa tcgccgccgc
     1501 gtcttcggaa atcaggcggt attcgataat gcggtggtaa cgcgtaaagt ccaccagacc
     1561 gcccgccctc aggcggttca aatggttgga aaccgctgtc gcaggcatgg gcagggattc
     1621 ggacagctcg gcaatattgc aatcgccgtc caaaagttgg agcagtatcg ccatacgttc
     1681 gggatgcgcc ataagtttga gtatggtgtg gagcggtatt gtgttcatcg gtattcctaa
     1741 aacctttgcc gcccgccaag cggattgacg ggcggcagat atggatgatt gtgattatct
     1801 ttataaatct tattataaat caaatattta tggatgattg tacaggattg tatgttcctt
     1861 ttcccacttt ttttgcaaac acgcgtaaag gcgggctttc agacagcata aaactgccgc
     1921 gcccgtcctt tcccctgccc tgccgatgcc tccgcgctgt cgggcaaaca aaatacctgc
     1981 ctgaaacgct gttttttcta aagcatcacg accttcacga aaaatgccgt ctgaagaata
     2041 tttcagacgg catttcctcc ttgaggcaat aaccggatta cggttaggcg gttccttgtc
     2101 tgacatatca gacaactgcc gacaccctaa aactcatgcc aagaaatcca aacctatgtc
     2161 caacgagcgg ctgctgtggg tcagatagcc gagggcgatg ccgtccacgc cggtttgcgc
     2221 cacgcgcttc aggcggtcga agccgatgcc gcccgatgct tcgcaataga cggtgtgggg
     2281 gtgggcggtt tgcgtgtggc agcggtttgc cgcttctttc agggtttcgt cgtccatgtt
     2341 gtccagcaaa atccgttccg cgcccgctgc gatggcttcg tccagttgtg ccaacgtgtc
     2401 cacttcgatt tccacgcagg tcaatgctcc gaccgcctgt tttgcctgcc gaacggcttg
     2461 ggcgatgctg ccgcaatagg cgaggtggtt gtctttgatg agtacggcat cgtccaaacc
     2521 catgcggtgg ttcacgccgc cgcccgccct gacggcgtat ttttgcagga cgcgcagcag
     2581 ggggatggtt ttgcggctgc acacgatgtc tgtaccgtat ttcgcgactt cggcaacggc
     2641 acgcgcggtg gcggtggaga tgccgctcaa gtgcgtgagg tagttgagcg cggtgcgttc
     2701 ggcggcgagc agcgcgcggg cgttgccttc gacggcggca agcgtctgac ctgcgcggac
     2761 gacttgcccg tctcggattt cggcttggaa gcggacggac ggatccatcg tctgaaaggc
     2821 gaggcgcgcc aagtccatac cggcgataac accgtcttcg cggctgacga ggaagagttt
     2881 ggcggttttg tcgggggcga tgacggcggc ggacgtaata tcgccgcgcc tgcccaaatc
     2941 ttcgctcaag gcttgttcca ccatggggcg caacaggggg tcgggcaggg gaaagagggt
     3001 gttttcagac ggcatggggt ttcctttgtt gaaaaagatg ggtgttgcac cgatgggcaa
     3061 aacttcgttt gatgccgtct gaaaacgggc taacggctgc ccagcggcag tccgatgtcc
     3121 gaaatcagcc tgtcgggcag gacgtcgtcg cggaagcggc aaagctgcgc gggacggcct
     3181 ttgctgcccg atacgccggt atccgacggc tcgatgaggt tttgctgctg aatctggcgg
     3241 cggaagtttt gcttgtgcag caatctgccg ctgatggctt cgacgctgtt ttgcagttgc
     3301 agcagcgtga attcgggcgg catcagttca aaaatcacgg ggcggtattt gattttggcg
     3361 cgcaggcgag acagggcggt cgccagtacg cggcggtggt cgtggcgcat gggctgcccc
     3421 gtgagcgcga agtcgaagtt tgcctgcggc tcggcggctt ccactatcag accgctttca
     3481 tacagcattt catagcgttg taaaacgtat tcttccgacc agttttccgg ttcgaccccc
     3541 cagcacaaat gaatgcgctt gagccgcatt tgacgcactt cctccgtgtc cgccgaattt
     3601 gcccaaatgc gcaggcggct gacgacggcg tcgcgctgtc cgccgtcggt gcgcaagtct
     3661 tcccacggga aatagccgta gcagtcctgc catttcgcat ccgggtgcag gatgctgtcg
     3721 gctgcctcgc gcaccagccc caaatagctg acgtacaaga cgggcatgcc gtgttcgttg
     3781 cggcggtggg tatcgacaaa ggtgtaaagc tgttccacat agcccatagg ctgcgaagtc
     3841 tgcttggcaa cccacagctt cacgcccgcc tgcagggaat tgcgcagagg ggagagcggg
     3901 ccgttgggca ggagtgtgcc ttgggcgacg gttaataccc gcaggccgcc gtcggtaacg
     3961 gcaatcaata cgggaaccag ctcgacgatg ctttgcggcg gggcttcggc ttcggggtag
     4021 gcatccatgc tcggctttct gcgggtggga aaggctttat tgtatagtgg attaaattta
     4081 aaccagtaca gcgttgcctc gccttgccgt actatttgta ctgtctgcgg cttcgtcgcc
     4141 ttgtcctgat ttttgttaat ccactataaa ccaaagcggt ttgtcggaac gaagcgggtc
     4201 ggttttacgg tatcgcaaac ctgttttcag acgaccttgc ttattatact caatttgagc
     4261 ataatataaa aatatttcaa aatataaacg gcaaatcttt atgccgtctg aaaaaccagc
     4321 cataaggaag tctcatgcaa accgccgccc gccgctcgtt cgattacgat atgcccctca
     4381 tccaaacgcc gacttccgcc tgccaaatcc gtcaggcgtg ggcgaaggtt gccgacacgc
     4441 ccgaccgcga gacggcaggc cgtctgaaag acgaaatcaa ggctttgctg aaggagaaaa
     4501 acgcggtctt ggtggcgcat tattacgtcg atccgctgat tcaggatttg gctttagaaa
     4561 cgggcggatg cgtgggcgat tcgctggaaa tggcgcgctt cggcgcggaa cacgaagcta
     4621 gtacattggt ggtggcgggc gtgcgcttca tgggcgagag cgcgaaaatc ctctgccctg
     4681 aaaaaacagt gctgatgcct gatttggagg cggaatgttc tttggatttg ggctgtccgg
     4741 aagaagcgtt ttcagcgttt tgcgaccaac accccgaccg cacggtcgta gtgtacgcca
     4801 acacttccgc cgccgtgaaa gcgcgtgccg actgggtggt aacgtcttcg gtggcgttgg
     4861 aaatcgtatc gtatttgaaa tcgcgcggcg agaagctgat ttggggacct gaccgccacc
     4921 tcggcgacta catccgccgc gaaacgggcg cggatatgct gctgtggcag ggttcgtgca
     4981 tcgtccacaa cgaattcaaa gggcaggagc tggcggcgtt gaaggcggaa caccccgaag
     5041 cggtggtgct ggttcatccc gaatcgccac aaagcgtcat cgaactgggc gacgtggtcg
     5101 gctcgaccag caaactgctc aaagccgccg tatcgcaccc tgaaaaaaaa ttcatcgtag
     5161 cgaccgactt gggcatcctg cacgaaatgc aaaagcaggc acccgacaaa gaatttatcg
     5221 ccgcaccgac ggcgggcaac ggtggaagct gtaaaagctg cgcgttctgc ccttggatgg
     5281 cgatgaattc actgggcggc atcaaatacg ccctgacaag cggacacaac gaaatcctgt
     5341 tggacagaaa gctgggcgaa gccgccaaac tgcctttgca gcgtatgctt gacttcgcgg
     5401 caggactcaa gcgcggggat gtgttcaacg gcatggggct cgcctgattt gccgtcaata
     5461 ttgccgtttc agacggcctc tcaaacaagg acaacaccat atgcaaaccg attgcgacgt
     5521 attgattgcc ggaaacgggc tggcggcact gacgctcgcc ctgtcgctgc ctgaatcgtt
     5581 ccgcatcgtc attttgtgca aaaaccggct ggacgacact gccagccgtc atgcgcaagg
     5641 cgggattgcg gcggcgtggt cgggagagga cgacatcgaa aaacacgttg ccgatacctt
     5701 agaagcgggc gcgggtttgt gcgacgaagc cgccgtccgc gccatcctgt cgcagggcaa
     5761 accggcaatc gaatggctgt tggcgcaggg tgtggcgttc gaccggaatc ataacgacct
     5821 gcacctgacg cgcgaaggcg ggcatacctg ccgccgaatc gcccacgtcg ccgactacac
     5881 gggcgaagcc gtcatgcaga gcctgcttgc ccaaatacgc cgccgcccgc acatccgcgt
     5941 ttgcgagcgg cagatggcgt tggacattca aaccgaatca ggtgtggcgt gcggactgat
     6001 cgtccttgac cgccgaacgc aagaaaccta cctcatccgc gcccgccata ccgtactcgc
     6061 aggcggcggc ttgggacaga tttacgccgc caccaccacg ccgcccgaat gcacgggcga
     6121 cgccatcgcc atggcgatac gcgcaggctg cgcagtcgaa aacctcgaat ttatccaatt
     6181 ccaccccaca ggcttggcaa gatcgtctga aaacggccgc accttcctga tttccgaagc
     6241 cgtgcgcggc gaaggcggca tcctgaccaa ccaagcgggc gaacggttta tgccgtatta
     6301 cgaccgccgc gccgaactcg cgccgcgcga catcgttgcc cgcgccatcg ccgccgaaat
     6361 cgccaaacaa acgcaagact tcgtctcact cgatatcagc catcaacccg cagcgttcgt
     6421 ccgccggcat ttcccgtcca tccatcggca ctgtttatcc caatgcggcc tggatatcac
     6481 gcgccaagcc atccccgtcc gccccgtgca acactacacc tgcggcggca tccaaaccga
     6541 cccctgcggc agaacttccc tgccgcagct ctactcctta ggcgaaaccg cctgcaccgg
     6601 cttgcacgga gccaaccgcc ttgccagcaa ctccctgctc gaatgtgtcg ttaccgccag
     6661 acttgccgcc caaaccatcg cagacggaca agcattccaa gccaaaacgt ctccaaggcc
     6721 gtctgaaagc ctctcctccg aagcaggcat cttttcagac ggcatccaaa gcgcattcag
     6781 ccgccccgtc ctgcaagcgt tcaaccaacg ccatctgggc atcctccgca acgataccgg
     6841 tctgcgctgc gccatcgccc agctgcggct ttggaaacaa aaccaaaccg aaccgcacac
     6901 cgcgtccgaa tacgaaaacc gcaacctgct cgaatgcagc ctcgccgtcg cccaagccgc
     6961 atacaggcgg agacagaaca tcggcgcgca ttttaatagt gattgttaag gttggctggt
     7021 tagaaaaaaa tcgttcaaat aaatttgaat agcatggttg agaaattggc attcagtttt
     7081 tagggttgcg taagttgggt tattattttg ttctaaaagt agaaaggccg tctgaaatat
     7141 ttttcagacg gcctttctac ttcctgagta ttttatctgc ctgactgtgc ccacacgttt
     7201 tgcaggtagg cgtaggtcag ctcggcggtg tcggacacta gcgcgatgtc gctgcccaag
     7261 tcttcggctt tgcccacgcc gatgggcaag gcgccggcgg ctttgatggc ggcgacgccg
     7321 gcgacggcgt cttcaatgcc gatgcattgg cggatgtctg cgtccacgcc ctcggcggcg
     7381 gcgaggaaga tgtcgggggc aggtttggaa tgcgcgacgg cggcagggtc ggcaatggcg
     7441 tcgaagaagt gggtcagccc catgcgttcg agcaggaacg ggccgttttt actggcggac
     7501 gcgagggcga tttttttgcc gtttgccctc aatgcttcca gtaggggcaa aatgccggga
     7561 tacacgtctt cgggtttgac tgcttgaatc atctcaacgt agttgtcgtt tttgcggcgg
     7621 gtcagttcgg cgaactcggc ttcgctgacg gttttgccgc cgtgtgcgag gatgcgtttg
     7681 agcgaatcgt cgcgcgatac gcctttgagc tgctcgttaa acttgcggtc gatgctgatg
     7741 cccagttctg tggcgagctt tttccatgcg cggtagtggt actcggcggt gtcggtgatg
     7801 acgccatcga gatcaaagag cactgcggta aaagtcattt tgcgccctcc ttatttttcc
     7861 aatgcaacgg tgtggctgcc gttgagcgtg atgtctttgc cgtacacctg caaatcgagc
     7921 ggctcgcctt tgagcagggt gaagacgacg ttttctttgc cgacggcgac tttaatcaga
     7981 cggcctcggt agttgatatg gaaggtgtag cctgtccacg cgctcggcag gaacggtgcg
     8041 aagctgagtt taccgcccca agttttcatt tgggcgaaac cttggacgat ggcgagccac
     8101 gagccggtca tagaagtaat gtgcaggccg tcttcggtgt cgttgttgta gttgtccaag
     8161 tccaggcgtg cggtgcgccg gtacatttcc acggcttttt cttctttgcc cagttcggcg
     8221 gcgagaatag agtggataca cggcgacaac gagctttcat gcacggtcat cggctcgtag
     8281 aagtcgaagt tgcggcgttt ttcgtcgata ttgaaacggt cgccgaagaa atagatgcct
     8341 tgcaatacgt ccgcctgttt gataaagggc gaacgcagga ttttgtccca cgaccatttc
     8401 tggttgagcg gcaaatcgtc gggcgaaagc gcggacacgg ggcggatgtc tttgtcgagg
     8461 aagccgtcgt gttgcacgaa tacgccgagt tcttcgtcat gaggacggta catattcgcg
     8521 ctgatgtccg cccatttttc caactcggcg gcgctcacgt tcaaatccgg acgcgggtat
     8581 ttcgccaggg cttcgcgggt gtagtccaat acccatgcgg cgagggtgtt ggtgtaccag
     8641 ttgttgttga tgttgttttc gtattcgttc gggccggtta cgccgtgaat catgtatttg
     8701 ccgctgcgtt tggagaagtg gacgcggtcc gcccagaagc gggacacttc gaccaagact
     8761 tccaagcctt ctttggcaag atagctttcg tcgccggtgt agttggtgta gttgtagatg
     8821 gcgtaaggaa tcgcgccatt gcggtggatt tcctcgaagg tgatttccca ttcgttgtgg
     8881 cactcgatgc cggtaaacgt taccatcgga tagagtgcgc ccgccaagcc ctgttcgcgc
     8941 gcgttgtgct gcgcctgcgg cagttggttg cggcggtatt gcagcaggtt gcgggtaact
     9001 tcgggttccg ccagtgcgag gtagagcggt acggcatagg cttcggtatc ccaataggtc
     9061 gcgccgccgt atttttcgcc ggtaaagcct ttggggccga tgttcaggcg cgcgtcttcg
     9121 ccgtagtagg tggagaacag ttggaacaga ttgaaacgga tgccttgctg cgcttcgtcg
     9181 ctgccttcga tgaccacgtc ggcgatttcc caacggtgca gccagcctgc tttgtgcgcg
     9241 tccagcaagg tttcaaacgc aacgcctgcg actttttccg acaaggcgcg gcctgcggct
     9301 ttcactgctt ccaagccctg ataatcgcgg ctggtggtaa caatcacgcg tttttcaaag
     9361 gttttgggcg tgccgccgac ttcggactcg aaagaattgg agacctgcca gtcggtttgg
     9421 ctgccgccga gggctttgaa gctgccggcg aaagtttgct cggcgttgac gataaattgt
     9481 tccacgccga agggattggc gacggtttgg gcggcaatgt aggagagact gtctgaaacg
     9541 cctttgtcca atacctgcca gaatttttct tcgtagttgg agtcttcgtt tttcacgtcg
     9601 gcatcgatga tggaatcgat gcggacttgg tgggttttgc cgtcaacgga tacggcttcc
     9661 cagcggatga ccgccaactc tttttgcgcg acggacagga atttacacac atcgaaacgc
     9721 acgccgaata cggtgaacga gcggcgcaac acgccgtgct gcatatcgag ttcgacggag
     9781 aagccggcaa catcgttttt cgccaagtcc acttcctgcc cgtcgacaaa gattttgact
     9841 ttgctgaaat tgagcgcgtt gatggcttta ccgaaatatt tggggtagcc gtttttccac
     9901 cagccgacgc gggttttgtc gggaaaccac acaccggcga tgtaggtacc caagtggctg
     9961 tcggcggaat aggtttcctc aaagctgccg cgcataccca tatagccgtt gcccaaactg
    10021 gtcaggctct cttgcagccg tttgtgttct ttttccagct ttgccgaacg cagcgtccaa
    10081 gggctgattt ccataattct tgtgtacatt tatgaagctc ctgtttggat tgatttgagg
    10141 gaatggtgaa atcttatagt ggattaacaa aaatcaggac aaggcgacga agccgcaaac
    10201 agtacaaata gtacggaacc gattcacttg gtgcttcagc accttagaga atcgttctct
    10261 ttgagctaag ccgaggcaac gccgtactgg tttttgttaa tccactataa aaaggccgtc
    10321 tgcaaccggt gttaggaagc tcctaagaaa gggattcgat gccgtaagca atcgtcgcct
    10381 ccctggtatc acccttgttc agacgaatat tgccgaactc gggccaatgc aggctgtcgg
    10441 gcagcgtctg cgcctcggtc gccagcgcgt cgtaaacgcc cgcatcgtgc cgcgcgaaat
    10501 cctgcggggc ggcggtaaag atgaccaagc cattgcggtc gctgtatatg ctgatacgac
    10561 ggcggcgtcc ggcttgcaac acagcggcgg gacggcctat atcggacggc acgcggtaag
    10621 cgtcgtcaaa accggcccga cccgtttcgc ggcgcagggc ggcaacggcg gcatccagcg
    10681 gcttgggccg gctgaaatca aatacttcga ggtcgtctga aaccgttgag acgggcagtt
    10741 tttcggcatc ggccggaata tgtccgccct gcggaatatg cagaaccgca tcgtgcaggc
    10801 ccgcgtccag ccgccagtaa atgtgcagcg tcgggtcgaa caccgtgtcg ccgagcgcgg
    10861 tggcgcgata gctaacggta agccggtcgt cctcgtccaa gcggtaggaa atatccaaat
    10921 ccaaatcgtt gggataaccg tcggccgact gttgcaggcg gctgcgcagc accaccgaac
    10981 ggccgtctgc cgccaccgcg ttgaaacggg taacggccag cccgtgcgaa ccgccgtgca
    11041 gcgcgttcct gccttcgttg gcctccacgc ggtaagtcct gccgttgatg tcgaacgccg
    11101 caccgcggat gcgtccggcc acgcgcccta tctgtttgtt aatctgaaac ggattgtccg
    11161 cataggaagc cgcatcatcg aacgacacca cgaggttttc gcgcacgccg tctgccaaaa
    11221 cggaaaattc ctgcacaatc ccgcccaagt ccagcacgca gacacgcgta ccacgccggt
    11281 tggacagcac atagccggtt acggcacgcc cgtcgatcag accgaaatcg cgggtagcgg
    11341 gggtatcgct catcgctcaa accccgccgt gtgtttcttt aatcaggaac acggaaaacg
    11401 cgcccagcag caggacgacg ccccctacca agaacatatt ggcctgcaaa ccgcccatca
    11461 tcgggaaaag cacgaaactc aacagcgaag cgacgatttg cggcatacag atagagccgt
    11521 taaacaggcc caagtaagtg cccatatgct tgcccgacaa ggcgttggtt acaatcgtca
    11581 gcggataagt gataatgccc gcccaagcga tgccgattaa ggtataagac aacaccagcg
    11641 cgtattggtt gccgatgaag aaaacggaga aaaagccgag cgcgcccaaa gccaaacagc
    11701 cgaaataacc cgccttatgg tatttattcg gcactttcgc caatacaaac gaacaaatca
    11761 ccgccgcaac cgactgcacc gccgccaaaa cgccgtacca gttgcccgcc tcctgataac
    11821 ctacggaaga cgcatcagtg gtgtgccaga cgttttccgc aatcgcgcct gccgagtaag
    11881 tccacatata ttggaaggcg aaccagcaga aaaactgtac cagagtaacc gtccaaaacg
    11941 ctttaggtgc cgtttttaag agttcgaacc agttggcttt ttcctgattc gcggcgacat
    12001 cgatgccgtg gtaacgggca taggtttccg ggtcgtattc tttgactttg aagattgtga
    12061 acgcactggt aataatcagt aatgccgcgc ccacatagaa tgctacgacc acggtttgtg
    12121 gcacaacgcc tttctcggcg gtgttcgcca aaccgatata cgcaaacaca aacggcagaa
    12181 tcgccgccac gaccgcgccc gtatttgcta agaaactttg aatcccgtag gcgtagcctt
    12241 tctgctcctc gttgaccatg tcgccgacca tcatcttaaa cggctgcatc gccatatttg
    12301 acgacacgtc caacagcgca atcatcagcg cgccgaacga caaagccgcc agcgacgcat
    12361 agccgaaacc gaagctgccc gagttcggca tcaaaatcat cacaataacc gcaatcagcg
    12421 tgccataaag cagatacggc agacggcggc cgcccaaacg cggcttccaa gtgcggtcgg
    12481 agtaatggcc gacaatcggc tgcaccagca tccccgccag cggcggcagg atgaaaaacc
    12541 agcccaaatt gtgcgggtct gcgcctagcg tttgaaaaat gcggctcatt tgcgagcttt
    12601 gcagggtaaa ggccgtctga acgccgagaa agccgaaact gagcatccaa atcgtgcttt
    12661 ttgccagcgc gggcaaacct tgttttgctg tttgaggcgt atattccgac ataaggtaaa
    12721 tccttttttg atttgaaaag tatagtagat taacaaaaac cagtacggcg ttgcctcgcc
//
LOCUS       DAXIDM010000053        12137 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000053 DAXIDM010000000
VERSION     DAXIDM010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12137
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.053"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            320..754
                     /locus_tag="ACFOAE_001265"
     CDS             320..754
                     /locus_tag="ACFOAE_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4124 domain-containing protein"
                     /protein_id="HFC6884745.1"
                     /translation="MNFALSVIMLTLASFLPVPPAGAAVFTWKDGGGNSYSDVPKQLH
                     PDQSQILNLRTRQTKPAVKPAQADAGKRTDGAAQENNPDTAEKNRQLEEEKKRIAETE
                     RQNKEENCRISKMNLKAVGNSNAKNKDDLIRKYNNAVNKYCR"
     gene            complement(802..2145)
                     /locus_tag="ACFOAE_001266"
     CDS             complement(802..2145)
                     /locus_tag="ACFOAE_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HFC6884746.1"
                     /translation="MFHSVNVFTGETLYRRPAQDYAEFERRLADLKMRGGAFAQLGVT
                     ERAARLQKFADRLEAEKERFAEMVCEEVGRCLQECRAEIGKSIELIRYYARLAPELLA
                     HKTIATQASLSQVRFEPLGVVFAVMPWNYPVWQVLRFAVPAMCAGNACAVKPAPSVAR
                     VSQALFDLVSDGIPLAGAWLDEAGTLKAVEDTDAMAFTGSTHTGRILAAHAGANLKKT
                     VLELGGSNAFIVMPDADLERAAAEACYSRFRDAGQSCNAAKRIIVTEAAADRFITLFL
                     AECAKLKMGDPKHPDTTLAPLHREDLRDRVHGQVEDAVSNGAVCLTGGKIPQGRGWFY
                     PATVLDRVNPACRVWREEVFGPAALILRAENEEHAIALANDSPFGLGACIYTADTERA
                     WRFAEKIQAGSVFINRHTSSDLRLPFGGVKDSGYGRELSEFGLYEFVNVKTYWQK"
     gene            complement(2150..2803)
                     /locus_tag="ACFOAE_001267"
     CDS             complement(2150..2803)
                     /locus_tag="ACFOAE_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
                     /protein_id="HFC6884747.1"
                     /translation="MGLGMEIGKLIVAFLVLINPFSALSLYLDLTNGHSTKERRKVAR
                     TAAVAVFAVIAVFALIGGTLLKVLGISVGSFQVGGGILVLLIAISMMNGNDNPAKQNL
                     GAQPETGQARPARNAGAIAVVPIAIPITIGPGGISTVIIYASAAKTYGDIALIIAAGL
                     VVSAICYAILIVAGKVSRLLGATGLTILNRIMGMMLAAVSVEIIVSGLKTIFPQLAG"
     gene            2954..3244
                     /gene="gatC"
                     /locus_tag="ACFOAE_001268"
     CDS             2954..3244
                     /gene="gatC"
                     /locus_tag="ACFOAE_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFC6884748.1"
                     /translation="MALTLADVDKIARLSRLHLTAAEKEKSLQELNDIFAMVEQMQTI
                     NTDGIEPMAHPHEAALRLREDEVTETDRAAEYQAVAPEVRNRLYIVPQVIEE"
     gene            3307..4752
                     /gene="gatA"
                     /locus_tag="ACFOAE_001269"
     CDS             3307..4752
                     /gene="gatA"
                     /locus_tag="ACFOAE_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFC6884749.1"
                     /translation="MTQYTLKQASVLLQSKQISAVELASAYLAAIAEKNPALNGYITI
                     DQDKTLAEARAADERIAQGNASALTGVPVAYKDIFCQTGWRSACASKMLDNFISPYTA
                     TVVQNLLDEGMVTLGRTNMDEFAMGSTNENSFYGAAKNPWNHEHVPGGSSGGSAAVVA
                     ARLAPAALGSDTGGSIRQPASHCGITGIKPTYGTVSRFGMVAYASSFDQAGPMAQTAE
                     DCAILLNAMAGFDPKDSTSLEREKEDYTRDLNQPLKGMKIGLPKEYFGEGNSADVQTA
                     LQNTIDLLKTQGAELVEVSLPQTKLSIPAYYVLASAEASTNLSRYDGVRYGHRAAQFG
                     DLEEMYGKTRAEGFGSEVKRRIMIGTYVLSHGYYDAYYLKAQKLRRLVADDFQTAFAR
                     CDLILAPTAPTAAPKIGADASPVETYLSDIYTIAVNLAGLPALTLPAGFSIGGLPIGV
                     QLVGNYFAEAKILGAAHQIQLNSDWHGKRPE"
     gene            4749..5681
                     /locus_tag="ACFOAE_001270"
     CDS             4749..5681
                     /locus_tag="ACFOAE_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HFC6884750.1"
                     /translation="MKQNRTFTFPDFRTVYSYAPLYRLQHLKYTLRKFFGKKEIYAFE
                     QFVNASPIRQGLFLHCPQNAYPLLREFVDRRFNCKRRLDAMTADFLMAEKLFGTDILH
                     QMEDYRFHLVLAHLSDGISLWLNRNDNCVEEGAWSLSLRDEAGNRLYMATFAFVGTHL
                     LTASVQGPAGEEAKDTVRRITKQLHGLRPQQLMVTALQYFAAVLGLDGAMGIAQKHQV
                     KLRWKLKKRVKMNYDAFWQEYGASLERDGYWHLPQTPARKDLADIESKKRSMYRKRYE
                     MLDNMVAEMKDGLKTEARGISDGIQTEKPLRRTA"
     gene            5724..7154
                     /gene="gatB"
                     /locus_tag="ACFOAE_001271"
     CDS             5724..7154
                     /gene="gatB"
                     /locus_tag="ACFOAE_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003698528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFC6884751.1"
                     /translation="MTWETVIGLEIHVQLNTKSKIFSGASTAFGAEPNAHAGVVECAL
                     PGVLPVMNREVVEKAIKLGLALDAKINRKNVFDRKNYFYPDLPKGYQISQLDLPIVEH
                     GKLEIVVGDDVKTINVTRAHMEEDAGKSVHEGLNGATGIDLNRAGTPLLEVVSEPEMR
                     SAAEAVAYAKALHSLVTWLDICDGNMAEGSFRVDANVSVRPKGQAEFGTRREIKNLNS
                     FRFLEQAINYEVEAQIEILEDGGKVQQATMLFDPEKGETRVMRLKEDAHDYRYFPDPD
                     LLPVIISDAQMQKAKAEMPELPKEMAARFVADYGVSEYDARLLTASRAQAAYFEEAAK
                     ESGQGKPTANWMNGELAAALNKEGMELADSPITAPRLAALVGKIADGTLSSKLAKKAF
                     EAMWAESEATIAEIIEKHGLQQMTDTGAIEAMVDEVLANNAKAVEQFKSGNEKALNAI
                     VGQVMKASKGKANPAQVQELIKAKLA"
     gene            7246..8256
                     /locus_tag="ACFOAE_001272"
     CDS             7246..8256
                     /locus_tag="ACFOAE_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="HFC6884752.1"
                     /translation="MNHTVTLPDQTTFAANDGETVLAAAARQNLNLPHSCKSGVCGQC
                     KAELVSGDIQMDGHSEQALSEAEKAQGKILMCRTTAQSDISINIPGYKADALPVRTLP
                     ARIESIIFKHDVALLKLALPKAPPFAFYAGQYIDLLLPGNVSRSYSIANPPDQEGILE
                     LHIRRRKNGVCSEMIFGSEPKVKEKGIVRVKGPLGSFTLQEDSGKPVILLATGTGYAP
                     IRSILLDLIRQNSSRAVHFYWGARHQDDLYALEEAQGLACRLKNACFTPVLSRPGEGW
                     QGRKGHVQDIAAQDHPDLSEYEVFACGSPAMTEQAKNLFVQQHKLPENLFFSDAFTPS
                     AS"
     gene            complement(8385..9017)
                     /gene="pdxH"
                     /locus_tag="ACFOAE_001273"
     CDS             complement(8385..9017)
                     /gene="pdxH"
                     /locus_tag="ACFOAE_001273"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004733 - pyridoxamine phosphate oxidase
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HFC6884753.1"
                     /translation="MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAQVNEPT
                     AVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFAAMTFFWPELE
                     RQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKH
                     PLHVPRPPHWGGYIVIPDLIEFWQGRPSRLHDRIQYRLLDGGWIRERLSP"
     gene            9248..10297
                     /locus_tag="ACFOAE_001274"
     CDS             9248..10297
                     /locus_tag="ACFOAE_001274"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFC6884754.1"
                     /translation="MSKQPTSKRQWRDGVAPSAKKTAKPFKSKARPKDETDKTASQPY
                     GQKASDGIKPQNLPKQRAAKAKKLVVRNPNQKIMEHARDLKERRSDLSRMEPERLQKV
                     LAASGVGSRREMEEWINNGWVTVNGKTAQLGDKVTPDDHVTVKGSIIKLKWADRLPRI
                     ILYYKQEGEIVSRDDPQGRVSIFDRLPQAASSRWVAIGRLDINTSGLLILTTSGELVQ
                     RFAHPSFEVEREYAVRVLGGLTGEQMRVLTEEGVMLEDGLAKVERIREQGGEGANKWY
                     NVVIKEGRNREVRRIFESQGLTVSRLVRVGFGPIGLPNRLKRGQFYELNPAEVANILK
                     WAEMLLPGERRRKKA"
     gene            complement(10366..11907)
                     /locus_tag="ACFOAE_001275"
     CDS             complement(10366..11907)
                     /locus_tag="ACFOAE_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HFC6884755.1"
                     /translation="MKFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPL
                     TKLIGITESAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFS
                     LGFFVSAFGVSTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIM
                     GFGGGAMLASPLSVSLMNAFSNAASVGVVETFAVLGLLYLALMMFGAFTIRVPADGWK
                     PEGYTAPKTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQEL
                     FSETSVGRQASVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL
                     YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAW
                     STAAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMACLLIIGLLCNLAVKSVHEKHH
                     EKDIKTAAHSGNPDDETAISDAYLVGEKVSGGGISVWWRWALAVIPLAYGVVMVFVKA
                     LDLFS"
BASE COUNT         3138 a         3676 c         2975 g         2348 t
ORIGIN      
        1 atttcagcca tcttcaataa attatagtgg attaacaaaa atcagtacgg cgttgcctcg
       61 ccttagctca aagagaacga ttctctaagg tgctgaagca ccaagtgaat cggttccgta
      121 ctatttgtac tttctgcggc ttcgtcgcct tgtcctgatt tttgttaatc cactatattt
      181 ttgggaatct gttttacccc aatatataaa gcaccatatt aaggcggagt ttcttcccca
      241 ctttgacccg aacccggaaa agacaccgcc caagccaatc ctgatgctgc cccgacagcc
      301 aaccattaag gaaatcctaa tgaactttgc tttatccgtc attatgttga ccctcgcctc
      361 tttcctgccc gtcccgcctg ccggagccgc cgtctttact tggaaggacg gcggcggcaa
      421 cagctattcg gatgtaccga aacagcttca tcccgaccaa agccaaatct taaacctgcg
      481 gacgcgccaa accaaaccgg cggtcaaacc cgcccaagcc gacgcaggga agcgcacaga
      541 cggcgcggca caggaaaaca atcccgacac tgccgagaaa aaccggcagc ttgaggaaga
      601 aaagaaaaga attgccgaaa ccgaacggca gaacaaagaa gaaaactgcc ggatttcaaa
      661 aatgaacctg aaggcggtgg gaaattcaaa tgcaaaaaac aaggatgatt tgattcggaa
      721 atacaataac gccgtaaaca aatactgccg ttaatcggct ctagcgcaaa cccgatgccg
      781 tctgaagcgg cacggggttt gtcatttctg ccagtaggtt ttgacgttga cgaactcgta
      841 cagcccgaat tcggacaatt cgcgcccgta accggaatct ttgactccgc cgaaaggcag
      901 gcgcaaatcg ctgctggtat ggcggttgat aaacaccgat cccgcctgta ttttttcggc
      961 aaaccgccaa gcgcgttcgg tatcggcggt ataaatgcag gcacctagcc cgaacgggga
     1021 atcattggca agggcgatgg catgttcttc gttttcggcg cgcaaaatca gggcggccgg
     1081 cccgaatact tcttctctcc agacgcggca ggcaggattt accctgtcta aaaccgtcgc
     1141 gggataaaac cagcctcgcc cttgtgggat ttttccgccg gtcaggcata ccgcgccgtt
     1201 tgaaacggca tcttcaacct gcccgtgaac cctgtcccgc aaatcttcgc ggtgcagcgg
     1261 tgcaagcgta gtatcgggat gtttggggtc gcccattttc aatttggcgc attcggcaag
     1321 aaacagcgtg ataaaacgat cggctgcggc ttcggttacg atgatgcgtt tggcggcgtt
     1381 gcacgattgc cccgcatcgc ggaaacggga ataacaggct tctgcggcgg cgcgttccaa
     1441 atcggcatcg ggcatcacga taaaggcgtt gctgccgccg agttccaaga cggttttctt
     1501 gaggtttgcg cccgcatgtg ccgcaaggat gcgccccgta tgcgtcgagc cggtaaacgc
     1561 catcgcatcg gtatcttcaa ccgccttgag cgtgcccgcc tcatccaacc acgcgcctgc
     1621 caaaggaatg ccgtctgaaa ccaaatcaaa caacgcctga ctgacgcgtg ccacgctggg
     1681 cgcgggtttg acggcgcacg cgttgcccgc gcacatagcg ggaacggcga aacgcaatac
     1741 ctgccagacg gggtagttcc aaggcatgac ggcaaacacc acacccaaag gctcgaagcg
     1801 cacctgactc aggctcgcct gcgtcgcgat ggttttgtgg gcgagcagtt cgggagcgag
     1861 gcgggcgtaa tagcgtatca gttcgataga cttgccgatt tccgcacggc attcctgcag
     1921 gcagcgtccg acttcttcgc acaccatttc cgcaaaacgc tctttctccg cctccaaacg
     1981 gtcggcaaat ttttgcagac gcgcggcacg ttcggttacg cccagttgcg cgaacgcccc
     2041 gccgcgcatt ttcaaatccg ccagccgccg ttcaaactcc gcataatctt gagctggacg
     2101 gcggtaaagc gtttcgcccg taaatacatt gacactgtga aacatcgaat caacctgcca
     2161 gttgcgggaa tatcgttttc agtcccgaca caataatctc caccgatacc gccgccagca
     2221 tcatacccat gatacggttt aaaatcgtca gccccgtcgc gcccagcagg cggctgacct
     2281 tcccggcaac gattaaaatg gcataacaaa tcgcactgac caccaaaccg gccgcgataa
     2341 tcaacgcgat gtcgccgtat gttttagccg ccgaagcgta aataatcacg gtcgaaatac
     2401 cgcccgggcc gatggtgatc ggtatggcga tgggcacgac ggcaatcgct ccggcattgc
     2461 gggcggggcg cgcctgcccc gtttccggct gcgcgccgag attctgcttg gcgggattgt
     2521 cgttgccgtt catcatagaa atggcaatca gcaacaccaa aattccgccg ccgacctgaa
     2581 acgaaccgac gctgatgccc aaaaccttca acagtgtacc gccgatcagc gcaaataccg
     2641 caatcacggc aaacacggca acggcggccg tccgcgcaac cttcctgcgc tccttcgtgc
     2701 tgtgcccgtt ggtcaggtca aggtaaagcg acaacgcgct aaacggattg atcagcacca
     2761 aaaaagccac aatcagcttg ccgatttcca tacccaatcc cattatttcc ccctccttca
     2821 aacccgtgcg gcaggcattc gatgctgcaa attgccgccg caacggattt ttccgttata
     2881 attaaaaatt caagcaatac gccccatcat acccgaacga cggtatcttt accatcagac
     2941 aaggatgctt ttcatggcac tgacacttgc cgacgtagac aaaatcgccc gactctcccg
     3001 actgcacctg actgcggcag aaaaagaaaa atcgcttcaa gaattaaacg acattttcgc
     3061 tatggtcgaa cagatgcaaa ccatcaacac agacggcatc gaaccgatgg cgcatccgca
     3121 cgaggccgcc ctgcgcctgc gcgaagacga agtaaccgaa accgaccgcg ccgccgaata
     3181 tcaggcggtt gctccagaag tacgcaaccg tctgtacatc gtaccgcaag ttatcgaaga
     3241 ataatccgaa tatgcttcag acggcatcag caataccgcc cgaagccctt taaggatgga
     3301 agatttatga cccaatacac attgaaacag gcaagcgtcc tgttgcagtc caaacagatt
     3361 tccgccgtcg aactggcaag cgcatacctt gccgccattg ccgaaaaaaa tcccgccctc
     3421 aacggctata tcaccatcga ccaagataaa acccttgcag aagcccgtgc cgccgacgaa
     3481 cgtatcgcgc agggcaacgc ctccgcgctt accggcgtac ccgtcgccta caaggatatt
     3541 ttctgccaaa ccggctggcg cagcgcgtgc gcttccaaaa tgctcgacaa cttcatctcc
     3601 ccttacaccg ccaccgtcgt ccaaaacctg ctcgacgaag gcatggtaac gctcggccgc
     3661 accaatatgg acgagtttgc tatgggttcg accaatgaaa actcattcta cggcgcggcc
     3721 aaaaatccgt ggaatcacga acacgtcccc ggcggttcgt cagggggttc agcagccgtc
     3781 gttgccgcac gccttgcccc tgccgcactc ggttcggata ccggcggctc catccgccag
     3841 cctgcttcac actgcggcat taccggtatc aaacctacct acggcacggt ttcccgcttc
     3901 ggtatggtcg cctacgcctc cagcttcgat caagccggcc cgatggcgca aactgccgaa
     3961 gactgcgcga ttctgttaaa cgcgatggca ggtttcgacc ccaaagactc caccagcctc
     4021 gaacgcgaaa aagaagacta cacccgcgat ttgaaccaac cgctcaaagg catgaaaatc
     4081 ggcctgccca aagaatactt cggcgaaggc aacagcgccg atgttcagac ggcattgcaa
     4141 aataccatcg acctcctcaa aacccaaggc gcggaattgg tcgaagtttc cctgccgcaa
     4201 accaagctgt ccatccccgc ctactacgtc ctcgcctccg cagaagccag taccaacctt
     4261 tcacgttacg acggcgtacg ttacggacac cgtgccgccc aattcggcga tttggaagaa
     4321 atgtacggca aaacccgcgc cgaaggtttt ggcagcgaag tcaaacgccg catcatgatc
     4381 ggcacttatg tactgtcaca cggctactac gatgcctact atctcaaagc ccaaaaactg
     4441 cgccgcctcg ttgccgatga ctttcagacg gcatttgcac ggtgcgacct catcctcgcg
     4501 ccgaccgcac ccactgcagc ccccaaaatc ggagcggatg cttcgccggt tgaaacctac
     4561 ttgagcgata tctacaccat cgccgtcaat ctcgccggac tacccgcatt gaccctgcct
     4621 gcaggtttca gcatcggcgg actgcccatc ggcgttcagc ttgtcggcaa ctacttcgcc
     4681 gaagccaaaa tcctcggtgc ggcgcatcaa atccaactca acagcgattg gcacggcaaa
     4741 cgacccgaat gaagcagaac cgcaccttta ccttccccga ttttcgcacc gtttacagct
     4801 atgcgccttt atatcggctg caacatttaa aatacacatt gcgaaaattt ttcggaaaaa
     4861 aagaaattta cgccttcgag cagtttgtca acgcctcccc tatccgtcag gggctgttcc
     4921 tccactgccc gcaaaatgcc tatccgctgc tgcgcgaatt tgttgacagg cgttttaact
     4981 gcaaacgccg tttagatgcg atgacggcag attttctcat ggcggaaaaa ctgttcggca
     5041 cagacatcct gcaccaaatg gaagactacc gcttccattt ggtcttggcg cacctttcag
     5101 acggcatcag cttgtggctc aaccgcaacg acaactgcgt cgaagaaggc gcgtggtctt
     5161 tatctttgcg cgacgaagca ggcaaccggc tgtatatggc gactttcgcc tttgtcggca
     5221 cacacctgct gacagcctcc gtacaagggc ctgcgggtga agaagccaaa gacactgtcc
     5281 gccgcataac caaacaactt cacggcttgc gtccccaaca actgatggta accgccctgc
     5341 aatatttcgc cgccgtactc ggcttggacg gcgcaatggg cattgcacaa aaacatcagg
     5401 tcaaactgcg ctggaaactt aaaaagcgtg tcaaaatgaa ttacgacgca ttctggcagg
     5461 aatacggcgc aagtttggaa cgggacggct actggcatct cccccaaacc cccgcccgca
     5521 aagaccttgc cgacatcgaa agcaaaaaac gctcgatgta ccgcaagcgt tatgaaatgc
     5581 tggacaacat ggttgcagag atgaaggacg gtctgaaaac agaagcacgc ggcatttcag
     5641 acggcatcca aacggaaaaa ccgctccgcc ggacagcctg acgcgaagac tatcgaattg
     5701 atattttaga gaaagaagct cttatgacct gggaaaccgt aatcggcttg gaaatccacg
     5761 tccaattgaa caccaaatcc aaaatcttca gcggcgcatc gaccgcattc ggcgcagaac
     5821 ccaacgcgca cgccggcgtg gtggaatgtg ctttgccggg cgtactgccg gtaatgaacc
     5881 gtgaagtcgt tgaaaaagcc atcaaattag gcttggcttt ggatgcgaaa atcaaccgga
     5941 aaaacgtgtt cgaccgtaaa aactacttct atcccgactt accaaaaggc tatcaaatca
     6001 gccagttgga cttaccgatt gtcgaacacg gcaaattgga aatcgtagtc ggcgacgatg
     6061 tgaaaaccat caacgtaacc cgcgcccata tggaagaaga cgcgggcaag tccgtacatg
     6121 aaggcttgaa cggcgcgacc ggtatcgacc tgaaccgcgc cggcacgcct ttattggaag
     6181 tggtgtccga acccgaaatg cgctccgccg ccgaagccgt tgcctacgcc aaagccttac
     6241 acagcttagt aacctggctg gacatttgcg acggcaatat ggcggaaggt tcattccgcg
     6301 tcgacgcaaa cgtatccgtg cgtccgaaag gtcaagcaga gttcggcacg cgccgcgaga
     6361 ttaaaaacct caattccttc cgctttttgg agcaggcaat taattacgaa gtggaagcgc
     6421 aaatcgagat tttggaagac ggcggcaaag tacagcaggc aaccatgctg ttcgaccctg
     6481 aaaaaggtga aacccgcgtg atgcgcttga aagaagacgc gcacgactac cgctacttcc
     6541 ccgaccctga tttgctgccc gtcatcattt cagacgccca aatgcaaaaa gccaaagcag
     6601 aaatgcccga gctgccgaaa gaaatggcag cgcgtttcgt ggcggattac ggcgtgtccg
     6661 aatacgacgc gcgcctgctc accgcaagcc gcgcacaggc cgcctatttt gaagaagccg
     6721 ccaaagagag cggacaaggc aagccgactg ccaactggat gaacggcgaa ctcgccgccg
     6781 cactgaacaa agaaggcatg gaacttgccg acagcccgat taccgctccg cgcctcgccg
     6841 cgctggtagg caaaatcgcc gacggcacat taagcagcaa attagcgaaa aaagcctttg
     6901 aagccatgtg ggcagaatcc gaagccacca ttgccgaaat cattgaaaaa cacggtttgc
     6961 agcaaatgac cgataccggc gcgattgaag ccatggtgga cgaagtgctg gcaaacaacg
     7021 ccaaagccgt ggaacagttc aaatccggca acgaaaaagc cctgaatgcg attgtgggac
     7081 aagtgatgaa ggccagcaaa ggcaaagcca accccgcgca ggttcaagag ctgattaaag
     7141 ccaaacttgc ctgacaagca agatgccgtc tgaaacccaa atccgacgtt cagacggcat
     7201 tttcacagtc tgaccacatt aaaacagcat aaaaaacaat attccatgaa ccacaccgtt
     7261 accctgcccg accaaaccac ctttgccgcc aacgacggcg aaaccgtttt ggccgctgcc
     7321 gcccgacaaa acctcaacct gccccattcc tgcaaaagcg gtgtctgcgg acaatgcaaa
     7381 gccgaactgg tcagcggcga tattcaaatg gacggacact cggaacaggc tttatccgaa
     7441 gcagaaaaag cgcaaggcaa gattttgatg tgccgcacca ccgcgcaaag cgatatcagc
     7501 atcaacatcc ccggctacaa agccgatgcc ctacccgtcc gcaccctgcc cgcacgcatc
     7561 gaaagtatta ttttcaaaca cgatgtcgcc ctcctgaaac ttgccctgcc caaagccccg
     7621 ccgtttgcct tctacgccgg gcaatacatt gatttactgc tgccgggcaa cgtcagccgc
     7681 agctactcca tcgccaatcc gcccgaccaa gaaggcattt tggaactaca catccgcagg
     7741 cgcaaaaacg gtgtctgctc ggaaatgatt ttcggcagcg aacccaaagt caaagaaaaa
     7801 ggcatcgtcc gcgttaaagg tccgctcggt tcgtttaccc tgcaggaaga tagcggcaaa
     7861 cccgtcatcc tgctggcaac cggcacaggc tacgccccca tccgcagcat cctgctcgac
     7921 cttatccgcc aaaacagcag ccgcgccgtc catttctact ggggcgcgcg tcatcaagat
     7981 gatttgtatg ccctcgaaga agcacaaggg ttggcatgcc gtctgaaaaa cgcctgcttc
     8041 acccccgtat tgtcccgccc cggagagggc tggcagggaa gaaaagggca cgtacaagac
     8101 atcgcggcac aagaccaccc cgacctgtcg gaatacgaag tatttgcctg cggctctccg
     8161 gccatgaccg aacaagcaaa aaatctgttt gtgcaacagc ataagctgcc ggaaaacttg
     8221 tttttctccg acgcattcac gccgtccgca tcataattcc ccggtataaa aaagattcag
     8281 gctttccgtt cggaacacaa aaaacttccc gtccgtattt tccccataaa aaatgccgtc
     8341 tgaagcccga ttccggtttt cagacggcat atgttttttc ctgttcaagg cgacagccgc
     8401 tcgcgtatcc agccaccatc cagcaaacgg tattggatgc ggtcgtgcag cctgctcggc
     8461 ctgccctgcc aaaactcaat caaatcggga atcacaatat agccgcccca atgcggcgga
     8521 cgcggcacgt gcaaaggatg tttgagtccg accgccgccg cctttgccac caataccgcc
     8581 ttgttcggaa tcacctcgct ctgcgcactt gcccacgcac ccaaacggct ctgatacggg
     8641 cggctctcaa aatattcgtc cgacaacttc tccgccagcc tttcaacacg cccttccacg
     8701 cgcacctgac gctccagctc cggccaaaaa aacgtcatcg ccgcaaatgg atgagcatcc
     8761 agcgaacgtc ccttacggct gtgataattc gtaaagaaaa caaaaccttc agaattaact
     8821 tccttcagca gcaccatacg gctgttgggt ctgccgcgtc cgtcgaccgc cgccacatta
     8881 accgccgtcg gctcgttgac ctgtgcgcgt accgcctcgt ccaaccaccg ctcgaactgc
     8941 tcgatcggat tgtcggcgca atcgccttcc gacaattccc gtttactgta atcttcccga
     9001 atattgtgca aatccattta ccgctcctct tgtcatttga aagattctac ccccgcacgc
     9061 aaaccgattt caaccgttgc acaaactttg cctcgcttct ccaaacctca ggacacaacg
     9121 atttcatccg caaaaccgcc gcataaggta caatatcgaa ccgtccgacc gagggcggca
     9181 ttttatcaac ccgtcctgcc gcacacgccg cagaagaacc gccttatcag gcgagttagg
     9241 aaaaatgatg tccaaacagc ccaccagcaa acgccaatgg cgcgacggcg tagccccgtc
     9301 tgccaagaaa accgccaaac ctttcaaaag caaagcccgt cccaaagacg aaacggacaa
     9361 aaccgcatcc caaccttacg gacaaaaagc ttcagacggc atcaaacctc aaaacctccc
     9421 caaacagcgc gccgccaaag ccaaaaaact cgtcgtccgc aatcccaacc aaaaaattat
     9481 ggaacacgcg cgcgatttaa aagaacgccg cagcgaccta tcgcgcatgg aacccgaacg
     9541 cctgcaaaaa gtgcttgccg cgtccggcgt cggctcgcgc cgcgaaatgg aagaatggat
     9601 caacaacggc tgggtaacgg tcaacggcaa aaccgcgcaa ctgggcgaca aagtcacccc
     9661 cgacgaccac gttaccgtca aaggcagcat catcaaactc aaatgggccg accgcctgcc
     9721 gcgcatcatc ctatattaca aacaagaagg cgaaatcgtt tcccgcgacg acccgcaagg
     9781 ccgcgtcagc atattcgacc gcctgccgca ggccgccagc agccgctggg tcgccatcgg
     9841 acgcttggac atcaacacca gcggacttct gattcttacc acctccggcg aactcgtcca
     9901 acgtttcgcc caccccagct tcgaagtcga acgcgaatac gccgtgcgcg tactgggcgg
     9961 gctgaccggc gaacaaatgc gcgtcctcac cgaagaaggc gtgatgctcg aagacggctt
    10021 ggcaaaagtc gaacgcatcc gcgaacaagg cggcgaaggc gcgaacaaat ggtacaacgt
    10081 cgtgattaaa gaaggccgca accgcgaagt gcgccgcatt tttgaaagcc aaggactcac
    10141 cgtcagccgc ctcgtgcgcg tcggcttcgg ccccatcgga ctgcccaacc gcctcaaacg
    10201 cggacagttc tacgaactca accccgccga agtcgccaac atcctcaaat gggcggaaat
    10261 gctgctgccg ggcgaacgcc gccgcaaaaa agcctaaacc cgccaaaaca caaaaatgcc
    10321 gtctgaaaca tctactgttt cagacggcat tttattcggg cgttttcagg agaaaaggtc
    10381 gagtgctttg acaaagacca tcaccacgcc gtaggcgagc ggtatgacgg ccaatgccca
    10441 acgccaccag accgatatgc cgccgccgga aactttttcg cccacaaggt aagcgtcgga
    10501 tatggcggtt tcgtcatcgg ggttgccgct gtgtgcggcg gttttgatgt ctttttcgtg
    10561 gtgtttttcg tgtacggatt tgacggcgag gttgcacaac aaaccgataa tcagcaggca
    10621 cgccatgatg tacatggtta cgctgtatgc ctgtgccgcc ggtatgccgc tgtcgatttg
    10681 gctttggcgt atgtaattga ccagtaccgg gccgatgacg gcggcggttg accaggccag
    10741 caggatgcgc ccgtgaatcg cgccgacctg ataggtgccg aacaggtctt tcaggtaggc
    10801 gggaatggcg gcaaatccgc cgccgtacat ggaaataatc acgcaaaagc cgatgatgaa
    10861 cagggctttg ctgccgccct cgccgatgga gggaacggcg aaatacagca gcgaaccgag
    10921 tacgaagaaa atggtgtagg tgtttttgcg tccgattttg tcggaaacgc tcgaccataa
    10981 aaagcgtccg cccatgttaa acaggctcag gaggctgacg aagcctgccg ccgcacctgc
    11041 gccgactgac gcctgcctgc ctacggaggt ttcggaaaag agttcctgaa tcatcacgga
    11101 tgcctgaccc aatacgccaa tgccggcggt tacgttcagg cacaataccc agaacaacag
    11161 ccaaaattgc ggcgttttca tggcttgtga cacgttgaca tgattgctgc tgaccagctt
    11221 gttttgcgtt ttcggcgcgg tatagccttc aggtttccag ccgtcggcag gtacgcggat
    11281 ggtaaacgcg ccgaacatca tcagtgcgag gtaaagcagg cccaatacgg cgaaggtttc
    11341 aacaaccccg actgaagcgg cgtttgaaaa ggcgttcatc agtgatacgg aaagcggaga
    11401 ggccagcatt gcgccgccgc cgaaacccat aatcgccaaa ccggtcgcca tacccggctt
    11461 gtcgggaaac catttcatca gtgtggaaac cggcccgatg tagcctaagc ctaagcctac
    11521 gccaccgatg acgccgttgc ccaaataaag caggaagagg ttgtgcgtac tcacgccgaa
    11581 tgcggatacg aagaagccca ggctgaaaca gcaggcggcg gcaaatatgg ctttgcgcgg
    11641 ccctacccgt tccatccacg taccgaacag ggcggccgac gcgcccagca tcgcgagtgc
    11701 gatactgaaa atccaaccta cggtcgtcag cttccaatct ccggccgccg attcggttat
    11761 gccgataagt ttggtcagcg gcgcgttgaa tacggaatag gcgtaaatct gcccgatggc
    11821 aaggtgcacc gccaatgctg cgggcggtac gagccaacgg ttgaaacccg gcttggcaat
    11881 gcttgcctca cggtctaaaa acttcataac atcctctttc tgtcagttga aaaataaaat
    11941 ttcatttgct caatggaaac ttattgaaaa ctataaaaaa atatcggatc ggttttttat
    12001 ccgccccaag atgccccgtc tgaaacattt cgggtgtacg gaaaggtttc tgttttttcc
    12061 gacaaattcc tgcggctttt cgcttccgga ttcccgcttt tgcgggaatg acgaattaaa
    12121 gattatctta aggtcaa
//
LOCUS       DAXIDM010000054        12096 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000054 DAXIDM010000000
VERSION     DAXIDM010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12096
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.054"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            204..383
                     /locus_tag="ACFOAE_001276"
     CDS             204..383
                     /locus_tag="ACFOAE_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884756.1"
                     /translation="MFWYVIGFCAFVVALLSLWVNAGAFGMQEDDTPQSDYERRLGLG
                     AKLKNKNPDTDEKRQ"
     gene            complement(597..1598)
                     /locus_tag="ACFOAE_001277"
     CDS             complement(597..1598)
                     /locus_tag="ACFOAE_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFC6884757.1"
                     /translation="MIDGQTTEPKQKTRIILAPMQGLVDDVMRDLLTRIGGYDECVSE
                     FVRITHTVHSQSIWLKYVPEIANGNKTFSGTPCTVQLLGSDADNMAANALEAVRFGAN
                     KIDLNFGCPAPTVNKHKGGAILLKEPELIFHIVKTLRGRLPAHIPLTAKMRLGYEDKS
                     RALECACAIAEGGACGLTVHARTKAEAYEPPAHWEWIRKIRDTVNIPVTANGDVFSLQ
                     DYIGIKTISGCNSVMLGRGAVIRPDLARQIKQYENGGPVKDTDFAEVSKWIRQFFELC
                     LTKEANNKYPLARLKQWLGMMKKEFAAAQNLFDRVRTVKDADEVRNILAEFEREMNT"
     gene            complement(1675..5508)
                     /locus_tag="ACFOAE_001278"
     CDS             complement(1675..5508)
                     /locus_tag="ACFOAE_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3683 domain-containing protein"
                     /protein_id="HFC6884758.1"
                     /translation="MTTTTAPQRIREIPYNYTSYTDREIVIRLLGDEAWQILQDLRGQ
                     RKTGRSARMLFEVLGDIWVVVRNPYLVDDLLEHPKRRAALVREMRHRLNEIRKRRDDN
                     RQVDVLVAAAEKAVERFDSSFDETIQKRHQILERLSKITKPHNIMFDGLARVTHVTDA
                     TDWRVEYPFVVVNPDTEAEIAPLVRALIELDLVIIPRGGGTGYTGGAVPLDANSAVIN
                     TEKLDKHRGVEYVELAGLDGKHPIIHCGAGVVTRRVEETAHQAGLVFAVDPTSADASC
                     VGGNVAMNAGGKKAVLWGTALDNLAYWNMVNPQGEWLRIERVHHNFGKIHDEETAVFD
                     VHTLDSDGRNIVNTKRLEIPGHKFRKVGLGKDVTDKFLSGLPGVQKEGTDGIITSVAF
                     VLHKMPKYTRTVCMEFFGTVATATPSIVEIRDFLLAHESVRLAGLEHLDWRYVRAVGY
                     ATKAAGKGRPKMVLLADVVSDDEAAVQAAAEHICELARARDGEGFIAVSPEARKTFWL
                     DRSRTAAIAKHTNAFKINEDVVIPLERLGEYSDGIERINIELSIQNKLKLCAALEQYL
                     SGKLPIDKMGTDLPTAELLGERGKHALAHVSAVKARWEWLLANLDAPLADYKARYGAA
                     VHAAPEAKDDESCFTAFRDFRLRVSVKADVMKPLSEIFSGKTDTKIIQGLGKIHAKTV
                     RSRVFVALHMHAGDGNVHTNIPVNSDDADMLQTAYRSVERIMKIARSLGGVISGEHGI
                     GITKLEFLTDEDLQPFWNYKNQVDPKHTFNRHKLMKGSDLRNAYTPSFELLGAESLIM
                     EKSDLGTIADSVKDCLRCGKCKPVCSTHVPRANLLYSPRNKILGVGLLTEAFLYEEQT
                     RRGVSVKHFEELMDIGDHCTVCHRCVKPCPVNIDFGDVTVAVRNYLADSGHKRFAPAA
                     SMGMAFLNATGPKTIKALRAAMIQTGFPAQNFAYKIGKLLPIGTKKQKAEPKATVGTA
                     SIKEQVIHFINRPLPKSVPAKTPRSLLGIEDGKSIPIIRNPASPEDAEAVFYFPGCGS
                     ERLFSQIGLAVQAMLWHVGVQTVLPPGYMCCGYPQDAGGNKAKAEEMSTNNRVAFHRM
                     ANTLNYLDIKTVVVSCGTCYDQLEKYRFEEIFPGCRIIDIHEYLLEKGVKLNGVKGQQ
                     YLYHDPCHTPIKTMNATQMASNLMGQKVVLSDRCCGESGMFAVKRPDIATQVKFRKQE
                     EIEKNLKELPQGEPVKMLTSCPACLQGLSRYTDDNNMPADYIVIEMAKHILGENWLDE
                     FVKKANNGGVEKVLL"
     gene            5769..5865
                     /gene="ffs"
                     /locus_tag="ACFOAE_001279"
     ncRNA           5769..5865
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACFOAE_001279"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            6086..6505
                     /locus_tag="ACFOAE_001280"
     CDS             6086..6505
                     /locus_tag="ACFOAE_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884759.1"
                     /translation="MKKLLMITLTGMLAACATGVNVGRLMVEMPQGERSVVVQVPATN
                     NPLSDTVAVGMIKTSGSPSASNMIEMLGADNINVGVVGSSQMLNKATALYSLNHAKKV
                     GNNVSVYMMGDSESDKADLENAANAKNIKLHYFFNQK"
     gene            6602..8293
                     /gene="dld"
                     /locus_tag="ACFOAE_001281"
     CDS             6602..8293
                     /gene="dld"
                     /locus_tag="ACFOAE_001281"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016901 - oxidoreductase activity, acting
                     on the CH-OH group of donors, quinone or similar compound
                     as acceptor [Evidence IEA];
                     GO_process: GO:0006089 - lactate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019516 - lactate oxidation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HFC6884760.1"
                     /translation="MNASQLISSLTQTVGEKYIITDPAKTEQYRQGYRFGEGKALAVV
                     RPGSILEMWKILQACVEADVIVITQAANTGLTGGSTPDGNDYDRDIVIVNTMRMNIIQ
                     TINDNEQVVCLPGSTLNQLELLLKPLGREPHSVIGSSCIGASVLGGVCNNSGGALVQR
                     GPAYTEMALFSQINEEGRLELVNHLGIDLGDTPEEILTNLQGHHYQKKDIKQDAGKGH
                     DHAYCEHVRQVDEPTAARFNADPARHYEASGCAGKLMVFAVRLDTFPQEKQTAVFYIG
                     TNDINELTDIRRAALGEFESLPVSGEYIHRHAFDIADVYGKDTFYVIKKFGTHQLPKL
                     FDLKARVDRFGKKASFLPKHFSDKAMQFVSKYLPDHLPKSMRDYRNKYEHHLILKMGG
                     KGVDEARAFLKEYFSHHGGAFFECNAEETQAAMLHRFAVASAAIRYRAVHDDEVEDLV
                     ALDIALRRDDRDWFEKLPQEIDNKIIHKLYYGHFMCHVFHQDYIIKKGNDCMALEHEM
                     LHLLDQRGAQYPAEHNVGHLYEAKPALKQFYRKLDPTNSFNPGIGKTSKKKNWAE"
     gene            8425..8532
                     /locus_tag="ACFOAE_001282"
                     /pseudo
     CDS             8425..8532
                     /locus_tag="ACFOAE_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8588..8959
                     /locus_tag="ACFOAE_001283"
     CDS             8588..8959
                     /locus_tag="ACFOAE_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HFC6884761.1"
                     /translation="MKPYKIYTHPALPPQAVKQGWSWPGLLFGTLWACFKRMWGLGLG
                     LTGAIFVLAVFAQLVYGDTPATDSAFNVLGLAVSVWFGAKGNSLYARHLLSRGYTELP
                     ETVQAANPQAALAQYFGRGGR"
     gene            9114..9662
                     /locus_tag="ACFOAE_001284"
     CDS             9114..9662
                     /locus_tag="ACFOAE_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFC6884762.1"
                     /translation="MARLTVHTLETAPEAAKARVEAVLQNNGFIPNLIGVLANAPEAL
                     SFYQEVGKLNAANSLTAGEVEVIQIIAARTNQCGFCVAGHTKLATLKKLLSEQSVKAA
                     RALAAGEFDDAKLGALAAFTQAVMAKKGAVSDEELKAFFDAGYNQQQAVEVVMGVALA
                     TLCNYVNNLGQTEINPELQAYA"
     gene            9797..10888
                     /locus_tag="ACFOAE_001285"
     CDS             9797..10888
                     /locus_tag="ACFOAE_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HFC6884763.1"
                     /translation="MNAQTLIANVAELVKTKLKPIVDDIDRKGYYPEAFMRELGAIGG
                     FGAVGTEAEGGNGLGLATQIAVLREIGKECGATSFSAWCQAACAWYLHQTPNRAVKDK
                     YLADILQGKVLAGTGMSNTVKHLAGIEKHNLQAERADGGYTVNGALPWVSNIGEDHIW
                     ANTAQIGGGYVMFITGGQWEGVSLQNCPEFCALEGTRTFSLNFKDVFIPDEDIIAAPE
                     QFADYIQSIKAGFILLQIGIGAGVIDGSLGIIRLANIVNAEVNRYLDDGYDSLKARLD
                     GAWAETERLAGLAWNNTPDTLATLKLREAAAVLALAATQSAALHSGAKGYLMRSPAQR
                     RVREAMFVAIVTPAIKHLRKEIAAIEAAK"
     gene            11273..11443
                     /locus_tag="ACFOAE_001286"
     CDS             11273..11443
                     /locus_tag="ACFOAE_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003744701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HFC6884764.1"
                     /translation="MAQYMCGPCGWIYDEEHGDPEHGIPPGTKFEDIPDDWKCPECGV
                     GKEDFYLLDFVI"
BASE COUNT         2906 a         3260 c         3221 g         2709 t
ORIGIN      
        1 tggaagaagg tgctcatgga acatctccta aatgtcttgg tgggaattta gggaattttg
       61 gggaattttg caaaggtctc tatttgtact gtcttcggct cgccgccttg tccttattta
      121 aatttaattc actatatttg cccgtgcgtt tgtgataaat tcggcactgt atttgatatg
      181 attttaacaa atcgggaggg gcaatgtttt ggtatgtgat tggcttttgc gcctttgtcg
      241 tcgcgctgct gtcgctgtgg gtcaatgccg gcgcgttcgg tatgcaggaa gacgataccc
      301 cgcaatcgga ttatgaaagg cgtttgggct tgggtgcgaa gctgaaaaac aaaaatccgg
      361 atacggacga aaaacggcaa taaagacaac aaatgccgtc tgaaaggttt tcagacggca
      421 tttgctttgg agcggatata gtggattaac aaaaatcagg acacggcgac gaagccgcag
      481 acagtacaaa tagtacgaaa ccgattcact tggtgcttca gcaccttaga gaatcgttct
      541 ctttgagcta aggcgaggca acgccgtacc ggtttttgtt aatccactat acatattcaa
      601 gtattcattt ctcgctcaaa ttcagccaag atgttccgaa cttcgtccgc atccttaacc
      661 gttcggacgc ggtcgaacag attttgtgct gctgcaaatt ctttcttcat catacccagc
      721 cactgtttca gccgcgccag cggatatttg ttgtttgcct cttttgtcag gcacagctcg
      781 aaaaactgcc gtatccattt ggaaacttcg gcaaaatccg tgtctttgac cggcccgccg
      841 ttctcgtatt gcttgatttg ccgcgccaaa tcggggcgga tgaccgcgcc gcgaccgagc
      901 atcacgctgt tgcagccgct gattgttttg atgccgatat agtcctgcag gctgaaaacg
      961 tcgccgttgg cggtaacggg aatattgacg gtatctcgga ttttccttat ccattcccaa
     1021 tgcgccggcg gttcgtaagc ctcggctttg gtacgcgcgt gtacggtcag tccgcatgcg
     1081 cccccttcgg caatcgcaca ggcgcattcc aaagcccggc ttttatcttc atagccgagc
     1141 cgcatttttg cggtgagcgg aatatgtgcg ggcaaacgtc cgcgcagcgt tttgacgatg
     1201 tggaatatca gttccggctc ttttaaaagg attgcgccgc ctttgtgttt gttgacggtg
     1261 ggcgcggggc agccgaagtt caaatcgatt ttgttcgcac cgaagcggac ggcttccagc
     1321 gcattcgccg ccatattgtc cgcatcgctg cccaaaagtt ggacggtgca gggcgtgccg
     1381 gaaaacgttt tgtttccgtt ggcgatttcg gggacatatt ttaaccatat ggattgggaa
     1441 tgcacggtat gggtaatgcg tacaaattcg ctgacgcatt cgtcgtagcc gccaatacgc
     1501 gtcagcaggt cgcgcatcac gtcatcgacc agaccctgca taggggcaag gatgattcgg
     1561 gttttttgtt tgggttcggt tgtttgtccg tcaatcatga ttcgggtagg tatttgattc
     1621 aaacaatgcc gtctgaaggc tttcggcgtt cagacggcat ttccgtgtcc gttgttacag
     1681 caatactttt tccacgccgc cgttgttggc ttttttcaca aactcgtcta gccagttttc
     1741 gccgaggatg tgtttcgcca tttcgatgac gatgtagtcg gcaggcatat tgttgtcgtc
     1801 ggtgtagcgg ctcaagcctt gcaggcaggc ggggcaggag gtcagcattt tgacgggttc
     1861 gccctgcggc agctctttga ggtttttctc gatttcttcc tgtttgcgga atttgacttg
     1921 ggtggcgatg tcggggcgtt tgacggcaaa cataccggat tcgccgcagc agcggtcgct
     1981 taaaacgact ttctgcccca tcaggttgct tgccatttgg gtggcgttca tggttttgat
     2041 gggcgtgtgg caggggtcgt ggtagaggta ttgctgacct ttcacgccgt ttagtttcac
     2101 gcctttttca agcaggtatt cgtggatgtc gatgatgcgg cagccgggga agatttcctc
     2161 gaagcggtat ttttcgagct ggtcataaca agtgccgcaa ctgacgacga cggttttgat
     2221 gtcgaggtag ttgagggtgt tcgccatacg gtggaaagcc acgcggttgt tggtgctcat
     2281 ttcttcggct tttgccttat tgccgcccgc gtcttgcgga tagccgcaac acatatagcc
     2341 cggcggcagg acggtttgta cgccgacgtg ccagagcata gcttggacgg caagcccgat
     2401 ttggctgaac aggcgttccg aaccgcaacc ggggaagtag aacacggctt cggcatcttc
     2461 cggagaagcc ggattacgga tgatggggat gcttttgccg tcttcgatgc ccaataagga
     2521 gcgcggtgtt ttggcgggta cgcttttggg cagtgggcgg ttgatgaaat ggataacctg
     2581 ttctttgatt gaggcggtac cgacggttgc cttgggttcg gctttttgct ttttcgtgcc
     2641 gattggaaga agtttgccga ttttgtaggc aaaattctgc gcggggaagc cggtctgtat
     2701 catcgcggcg cgaagggctt tgatggtttt cgggccggtg gcgttcaaaa acgccatacc
     2761 cattgaagcg gcaggcgcaa atcgtttgtg gccggaatcg gcaaggtagt tgcggacggc
     2821 tacggttacg tcgccgaagt cgatgttgac ggggcagggt ttgacgcagc ggtggcacac
     2881 ggtgcagtgg tcgccgatgt ccatgagttc ttcaaagtgt ttgacggaaa cgccgcggcg
     2941 ggtttgttct tcgtataaga aggcttcggt cagcaagccc acgccgagga ttttgttgcg
     3001 ggggctgtac agcaggttgg cacgcggaac gtgggtggag cagacgggtt tgcatttgcc
     3061 gcagcgcagg cagtctttga cggaatcggc aatcgtgccg aggtctgatt tttccataat
     3121 cagcgattcc gcgcccaaaa gctcgaaaga cggcgtgtag gcgttgcgta agtccgagcc
     3181 tttcatcagt ttgtgacggt tgaaggtgtg tttcggatcg acttggtttt tgtagttcca
     3241 aaacggctgc aagtcttcat cggtcaaaaa ttcgagcttg gtgatgccga tgccgtgttc
     3301 gccggaaatc acgccgccga gcgaacgggc gattttcata atgcgttcga ccgaacgata
     3361 ggcagtctga agcatgtcgg catcgtctga attgaccgga atattggtgt gaacgttacc
     3421 gtcgccggcg tgcatatgca gggcgacgaa gacgcggctg cgtacggttt tggcgtggat
     3481 tttgcccaag ccttggataa ttttggtatc ggttttgccg ctgaagattt cagaaagcgg
     3541 cttcattacg tctgctttga cggacacgcg caggcggaaa tcgcggaatg cggtaaagca
     3601 gctttcatcg tctttggctt cgggcgcggc gtggacggct gcgccatagc gtgctttata
     3661 gtcggcaagc ggcgcgtcca agttggcaag cagccattcc caacgcgctt tgacagcgga
     3721 aacgtgggca agggcgtgtt tgccgcgttc gcccaacagt tcggcggtcg gcaggtcggt
     3781 tcccattttg tcgatgggga gtttgcccga aagatattgc tccaaggcgg cacagagttt
     3841 gagtttgttt tgaatggaaa gctcgatgtt gatgcgttcg ataccgtctg aatactcgcc
     3901 gagcctttcg agtgggatga ccacgtcttc gttgatttta aaggcgttgg tatgtttggc
     3961 gatggcggcg gtgcggctgc ggtcgagcca gaaggttttg cgcgcttcgg gcgatacggc
     4021 gataaagcct tcgccgtcgc gggcgcgggc aagttcacag atgtgctcgg cggctgcctg
     4081 tacggcggct tcgtcgtcgg aaaccacgtc cgccagcaag accattttcg gccgcccctt
     4141 gcctgctgct ttggtggcat aaccgacggc acggacgtaa cgccagtcca aatgttccaa
     4201 acccgccagc cgtacgcttt catgggcaag caaaaagtcg cggatttcga caatagatgg
     4261 cgtggcggtg gcaaccgtgc cgaaaaactc catacacacg gtgcgcgtgt atttcggcat
     4321 tttgtgcaat acgaaggcaa cgctggtgat gatgccgtct gtgccttctt tctgcacgcc
     4381 gggcagtccg ctcaagaatt tgtcggtaac gtctttgccc aaaccgactt tgcggaactt
     4441 gtgaccgggg atttccaaac gtttggtatt gacgatattg cggccgtctg aatccagcgt
     4501 atgtacgtcg aacacggcgg tttcttcgtc gtggattttg ccgaaattgt ggtgcacgcg
     4561 ctcgatacgc agccattcgc cttgagggtt aaccatgttc cagtaggcga ggttgtccaa
     4621 cgccgtcccc cacagcacgg cttttttgcc gcccgcgttc atcgccacat tgccgcccac
     4681 acaggacgca tcggcggaag tcggatcgac ggcgaacacc aaacccgcct gatgtgcggt
     4741 ttcttccacc cgccgcgtta ctacgcccgc gccgcaatgg ataatcggat gtttaccgtc
     4801 caagcctgcc agctcaacgt attcaacacc gcgatgcttg tcgagttttt cggtattgat
     4861 aaccgcgctg tttgcatcca gaggcacggc gccgccggta taacccgtgc cgccgccgcg
     4921 cggaataatg accaaatcca gctcgattaa ggcgcgcacc aaaggcgcga tttccgcctc
     4981 cgtgtcggga ttgacgacga caaaaggata ttcgacgcgc cagtcggtcg catcggtaac
     5041 gtgcgttacg cgcgccaatc cgtcaaacat gatgttgtgc ggcttggtaa ttttgcttaa
     5101 gcgttccaaa atttgatggc gtttttggat ggtttcatca aaactgctat caaaacgctc
     5161 cactgctttt tctgctgcgg caaccaacac atcgacttgc cgattatcgt cgcggcgttt
     5221 gcggatttca tttaagcggt ggcgcatttc gcgtaccagc gcggcgcggc gtttcgggtg
     5281 ctccagcaaa tcatcgacca gatacggatt gcgcacgacc acccaaatat cgcccaatac
     5341 ttcaaacagc atccgtgccg aacgtccggt tttgcgctgt ccgcgcaagt cttgcaggat
     5401 ttgccacgcc tcatcgccca gtaggcggat gacgatttcg cggtcggtat aagaagtata
     5461 gttataggga atttctcgaa tacgctgagg ggcagtagtc gtggtcatgg tgtgtccgtg
     5521 tttggcagtt tttatttgaa tgccgtctga aaagtcggtt tcaggcgagt ttgaaaaggc
     5581 gataatgtag ttcaattttt gatatttttc aatgccgaaa caggaaatac ccttatagaa
     5641 acaaaataac gctttgagaa attgttgaca atattatcaa atataaattt taggtggtgt
     5701 ttccggcgta tgaccgtatc aaaacggttg agtttttcag aaaacccgtt ataatgccgt
     5761 ttctctgagg cgggtctccc cgcatggcaa atcggaacac cgggtcaggg gcggaagcca
     5821 gcagcccact ccgatgcgcc agtgccgggg gtttggcccg ccgccctatt tgaaacgccg
     5881 gagcttcgat gttccggcgt tcccgtattg caccgatgcc gtctgaaagc cgttcagacg
     5941 gcattttctt tactttgcca taacgcatca ttacaatgta tccatacagg ccaatgaaga
     6001 accggcttca taaaaatgaa gtatggttca atttcaagtt tatgacgaac agggcagttt
     6061 gattaaagac taaaggagta ggcaaatgaa aaaacttcta atgataaccc tcaccggtat
     6121 gcttgcagct tgcgcaacag gtgtcaatgt cggccggctg atggttgaaa tgccgcaggg
     6181 agaacgttct gtcgttgtgc aggttcccgc gacaaataac ccgctttccg atacggtagc
     6241 tgtcggaatg attaaaacat ccggttcgcc ttcggcatca aatatgattg aaatgctcgg
     6301 cgcggacaat atcaacgtcg gcgtggtggg aagcagccaa atgcttaata aggcgaccgc
     6361 actttattcc ttaaaccatg caaagaaagt cggaaataat gtcagtgttt atatgatggg
     6421 cgacagcgaa agtgacaagg ccgatttgga aaacgcggca aatgccaaaa atatcaaatt
     6481 gcattatttc tttaaccaaa aataatttgc agcgtgcaac ttgccgcacc aaaatatcca
     6541 aattgaacat acggcggcgt accgggattt gcgccgccgc ttatcccgat aggagagtac
     6601 cgtgaacgcc tcgcaattaa tcagcagcct gacccaaacc gtaggcgaaa aatacatcat
     6661 caccgacccc gcgaaaaccg aacaataccg ccagggctac cgcttcggcg agggtaaggc
     6721 gttggcggtg gtgcgccccg gaagcattct ggaaatgtgg aaaattctac aggcgtgcgt
     6781 cgaagcggac gtgattgtga ttacgcaggc ggcgaatacc ggtttgacgg gcggctcgac
     6841 ccccgacggc aacgattacg accgcgacat cgtgatagtg aacactatgc ggatgaacat
     6901 catccaaacc atcaacgaca acgaacaagt cgtctgcctg cccggttcga ccctgaacca
     6961 gcttgaattg ctgctgaaac ctttggggcg cgaaccgcat tcggtcatcg gctcttcctg
     7021 catcggcgcg tccgtcttgg gcggcgtgtg caacaactcc ggcggcgcgt tggtacagcg
     7081 cggtccggcc tacaccgaaa tggcgttgtt ctcccaaatc aacgaagaag gcaggttgga
     7141 actggtcaac cacttgggca tagacttggg cgacacgccc gaagaaatcc tgaccaacct
     7201 gcaaggtcat cattatcaga aaaaagacat caaacaagac gcgggcaaag gacacgacca
     7261 cgcctattgc gaacacgtcc gccaagtgga cgaaccgacc gccgcgcgtt tcaatgccga
     7321 ccccgcccgc cattacgaag cctcgggctg cgcgggcaaa ctgatggttt ttgccgtccg
     7381 tttggacacc ttcccgcaag aaaaacaaac cgccgtgttc tacatcggca cgaacgacat
     7441 caacgagctg accgacatcc gccgcgccgc cttgggcgaa tttgaaagcc tgcctgtttc
     7501 cggcgaatac atccaccgcc acgctttcga cattgccgac gtgtacggca aagacacgtt
     7561 ttacgtcatc aaaaaattcg gtacgcacca actgccgaaa ttatttgact tgaaggcgcg
     7621 cgtggacagg ttcggcaaaa aagccagctt cctgcccaaa catttttccg acaaggccat
     7681 gcagttcgtc agcaaatacc tgcccgacca cctgcccaaa tccatgcgcg attaccgcaa
     7741 taaatacgaa caccacctga ttctgaaaat gggcgggaaa ggcgtggatg aggcgcgcgc
     7801 attcttaaaa gaatattttt cacaccacgg cggcgcgttt ttcgaatgca acgccgaaga
     7861 aacccaagcc gcgatgctgc accgtttcgc cgtcgcctcc gccgccatcc gctaccgtgc
     7921 cgtgcatgac gacgaagtgg aagatttggt cgcgctcgac atcgccctgc gccgcgacga
     7981 ccgcgactgg tttgaaaaac tgccgcagga aatcgacaat aaaatcatcc acaagctcta
     8041 ctacggacat tttatgtgcc acgttttcca tcaggattac atcatcaaaa aaggcaacga
     8101 ctgcatggcg ttggaacacg aaatgctgca tctcttagac caacgcggcg cgcaatatcc
     8161 cgccgaacac aacgtcggtc atttgtatga agccaaaccc gcgctcaaac agttttaccg
     8221 caaacttgac ccgaccaaca gcttcaaccc gggtatcggc aaaaccagca aaaagaaaaa
     8281 ctgggcggaa taagcgcgtc cgctttgaag gcaggcaatg ccgtctgaag gcaaaacgcc
     8341 gttcagacgg cattgtcggg tttgaagttc cccgtcgggt aatcgctttc aagccgtatg
     8401 ccggcacagg cgcgcgcgcc tcccaaatat agtggattaa atttaaatca ggacaaggca
     8461 acgaagccgc agacagtaca gatagtacgg caaggcgagg taacgccgta ctggtttaaa
     8521 tttaatccac tataaagtct gatcctacct tcccaaaggg cagggtttca accgaaaagg
     8581 aaacacgatg aaaccataca aaatctacac ccatcccgcc ctgccgcccc aagccgtcaa
     8641 acaaggctgg tcgtggccgg gtcttttgtt cggcacgctg tgggcgtgtt tcaaaagaat
     8701 gtggggtttg gggctcgggc tgacgggcgc gatattcgtg ctggctgtgt ttgcccaact
     8761 ggtttacggc gacacgcccg ccacagactc ggcgtttaac gtattgggct tggcggtttc
     8821 cgtctggttc ggcgcaaagg gcaacagcct ttatgcacgc caccttttat cgcgcggcta
     8881 taccgaattg cccgaaacag tccaagccgc caacccccaa gccgcattgg cgcaatattt
     8941 cgggcgcggg ggccgataag cgcgttttct tttccatcgt gccgtctgaa aaatgttcag
     9001 acggcatttc ttataacctt tcgtttgcag cacataacca atcagtcttt cctattccgt
     9061 tccgaaatgc gtaccatgcg cccgtaccca atatttgcga acaaggaaag aaaatggcac
     9121 gtttaaccgt acacaccctc gaaaccgccc ccgaagccgc caaagcgcgc gtcgaggcgg
     9181 tacttcaaaa caacggcttt atccccaacc ttatcggcgt attggcaaac gcccccgaag
     9241 ccttgtcgtt ttaccaagaa gtcggcaagc tcaacgccgc caacagcctg accgccggcg
     9301 aagtcgaagt catccagatc atcgccgccc gtaccaacca atgcggtttt tgcgtggcag
     9361 ggcacaccaa actcgcaacc ctgaaaaaac tcctgtccga acaatccgtc aaagccgcgc
     9421 gcgctttggc agcaggcgaa tttgacgatg ccaaactcgg cgcgctcgcc gccttcaccc
     9481 aagccgtaat ggcgaaaaaa ggcgcggtat ccgacgagga actcaaagca tttttcgatg
     9541 cgggctacaa ccagcagcag gcagtcgaag tcgtgatggg cgtagccttg gcaaccctgt
     9601 gcaactacgt caacaacctc ggacaaaccg aaatcaaccc cgaattgcag gcttacgcct
     9661 gatacggcaa accgcccgaa tatcgggcgg tttttcaaaa acaccccctc aaacaaaaac
     9721 aagccgccta agcggcaggg aagcagccgc gcatcaggcg cgcccccgat tcccccgcaa
     9781 accttaagga acaaagatga acgcccaaac cctgattgcc aatgttgccg aactcgtcaa
     9841 aaccaagctc aaacccatag tggacgacat cgaccgcaaa ggatactacc ccgaagcatt
     9901 tatgcgcgaa ctcggcgcaa tcggcggatt tggcgcagtc ggcacagaag ccgaaggcgg
     9961 caacggcttg ggtttggcaa cgcaaatcgc cgttttgcgc gaaatcggca aagaatgcgg
    10021 cgcaacctcc ttcagcgcgt ggtgtcaggc ggcttgcgcg tggtatctgc accaaacacc
    10081 caaccgggcc gtcaaagaca aatacctcgc cgacatcctg caaggcaaag tattggcggg
    10141 caccggaatg tccaataccg tcaaacacct tgccggtatt gaaaaacaca acctccaagc
    10201 cgaacgcgcg gacggcggct acacagtcaa cggcgcgctg ccgtgggtgt ccaacatcgg
    10261 cgaagaccac atctgggcaa ataccgccca aatcggcggc ggctacgtca tgtttatcac
    10321 cggcggacaa tgggaaggcg taagcctgca aaactgcccc gaattttgcg ccctcgaagg
    10381 tacgcgcacc ttcagcctga acttcaaaga cgtatttatc cccgacgaag acatcatcgc
    10441 cgcgcccgaa cagtttgccg actacatcca aagcatcaaa gcaggtttca tcctcctgca
    10501 aatcggcatc ggcgcgggcg tgattgacgg cagcctcggc atcatccgcc tcgccaacat
    10561 cgtcaacgcc gaagtcaacc gctatctcga cgacggctac gacagcctca aagcaaggtt
    10621 ggacggcgca tgggcagaaa ccgaacggct cgccggtttg gcatggaaca acacgccgga
    10681 cacattagcg accctcaagc tgcgcgaagc cgccgccgta ctggcacttg ccgccaccca
    10741 atccgccgcc ctgcattccg gcgcaaaagg ctacctgatg cgcagtcccg cccaaaggcg
    10801 cgtccgcgaa gcaatgtttg tcgccatcgt aactcccgcg atcaaacacc tccgaaaaga
    10861 aatagcggca atcgaagccg caaaataaac aggcggaaaa aaccgaaacc cccaccgcgt
    10921 cattcccgcg aaagcgggaa tccagccccc aacgcaacag gaatccatcg gaaaaaacag
    10981 aaacccccaa accgtcattc ccgcaaaagc gggaatccag ccccctaacg caacaggaat
    11041 ccatcgaaaa aaccgaaacc tccaaaccgt cattcccacg gaagtgggaa tccagtaatc
    11101 gaaaaaccac aggaatctat cgaaaaaaac cccaaccccc aaaaaaaccg ggcggatacc
    11161 gcaccatcct cccaaaccct gatttatagt ggatgaacaa aaatcaggac aaggcgaggc
    11221 aacgccgtac cggtttttgt tcatccgcta tacaaaaaac aaggaaacac aaatggcgca
    11281 atatatgtgc ggcccctgcg gctggattta cgatgaagaa cacggcgacc ccgaacacgg
    11341 catcccccct gggacaaagt ttgaagacat ccccgacgac tggaaatgcc ccgaatgcgg
    11401 cgtaggtaaa gaagatttct acctgttgga tttcgtgata tagcggcagc cgcaccctta
    11461 gggaaaaccc cgtcatccgg cgttccgcct gcggcggcag ggaacgccgt tttatagtgg
    11521 attaacaaaa atcaggacaa ggcgacgaag ccgcagacag tacaaatagt acggaaccga
    11581 ttcacttgtt aaagaatcgt tctctttgag ctaaggcgag gcaacgccgt actggttttt
    11641 gttaatccac tatatccgtt tgcgcccgcc aagccgtgtt gcacagatgc gacacggctt
    11701 ttttctttct gttgtcagaa tgtaaatttt cgtcaaaaaa catcaaaaat cacccccccc
    11761 cgaatttgcg taaaataaag tgtaatccct ttgatcataa gggaatgttg acaattagat
    11821 cgattctcct aggctgactt tcgcaataaa tggggttgtc aataattgtg tatggtcgtt
    11881 tgccgtccgg cggccgtcat tcccgcgcag gcgggaatcc agaaacgcaa cgcagcagga
    11941 ctttatcgga aaaaaccgaa atcccaccgc cgtcattccc gcgcaggcgg gaatccagca
    12001 acacaacgca gcaggacttt atcggaaaaa accgaaaccc caccgaccgt cattcccgca
    12061 aaagcgggaa tccaaaaacg caacgcaaca ggaatc
//
LOCUS       DAXIDM010000055        12060 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000055 DAXIDM010000000
VERSION     DAXIDM010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 12060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12060
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.055"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(18..1310)
                     /locus_tag="ACFOAE_001287"
     CDS             complement(18..1310)
                     /locus_tag="ACFOAE_001287"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HFC6884765.1"
                     /translation="MAVFPLSAKHRKYALRALAVSIILVSAAYIASTERTERVRPQRV
                     EQNLPPLSWGGSGVQTAYWVQEAVQPGDSLADVLARSGMARDEIARITEKYGGEADLR
                     HLRADQSVHVLVGGDGGAREVQFFTDEDGERNLVALEKKGGIWRRSASEADMKVLPTL
                     RSVVVKTSARGSLARAEVPVEIRESLSGIFAGRFSLDGLKEGDAVRLMYDSLYFHGQQ
                     VAAGDILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGRVLQEKGGFNIEPLVYTR
                     ISSPFGYRMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKGRKGGYGNAVMIRHA
                     NGVETLYAHLSAFSQAQGNVRGGEVIGFVGSTGRSTGPHLHYEARINGQPVNPVSVAL
                     PTPELTQADKAAFAAQKQKADALLARLRGIPVTVSQSD"
     gene            1388..2356
                     /locus_tag="ACFOAE_001288"
     CDS             1388..2356
                     /locus_tag="ACFOAE_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884766.1"
                     /translation="MKLTLALPSLNLDEDEIRIPLCLPAFNKILQYGSLHRQSCTASA
                     FYARYLWCGRLAERAAQSLNMPSEAVALATPVWQKMGMHQANVLTAEYLNVGTDEAER
                     LCRDLSAFYGDIPWRFVPVLPELWLVSLPCAYRWGAKPVLDLGGLLGADDQPDGEDAL
                     EWLRVQTEIQMWLAAHPVNHNRKKRGLPELNGLWLWDGTNGGAQGGTLFADTVWSRFH
                     PDRRALPDNFRAYEETAAHLPDTHHILFMDDLRLTALTGDRERYAAILQQWEERWFAP
                     LYEAVRTGKIKRLDITTDGQHGGTLTFKPADRWKFWRGAKTFDGIW"
     gene            complement(2557..4023)
                     /locus_tag="ACFOAE_001289"
     CDS             complement(2557..4023)
                     /locus_tag="ACFOAE_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC6884767.1"
                     /translation="MVIFYFCGKTFMPARNRWMLLLPLLASAAYAEETPREPDLRSRP
                     EFRLHEAEVKPIDREKVPGQVREKGKVLQIDGETLLKSPELLSRAMYSAVVSNNIAGI
                     RVILPIYLQQAQQDKMLALYAQGILAQADGRVKEAISHYRELIAAQPDAPAVRMRLAA
                     ALFDNRQNEAAADQFDRLKAENLPPQLMEQVELYRKALRERDAWKVNGGFSVTREHNI
                     NQAPKRQQYGKWTFPKQVDGTAVNYRLGAEKKWSLKNGWYTTAGGDVSGRVYPGNKKF
                     NDMTAGVSGGIGFADRRKDAGLAVFHERRTYGNDAYSYTNGARLYFNRWQTPKWQTLS
                     SAEWGRLKNTRRARSDNTHLQISNSLVFYRNARQYWMGGLDFYRERNPADRGDNFNRY
                     GLRFAWGQEWGGSGLSSLLRLGAAKRHYEKPGFFSGFKGERRRDKELNTSLSLWHRAL
                     HFKGITPRLTLSHRETRSNDVFNEYEKNRAFVEFNKTF"
     gene            complement(4265..6295)
                     /locus_tag="ACFOAE_001290"
                     /pseudo
     CDS             complement(4265..6295)
                     /locus_tag="ACFOAE_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_180374912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(7707..7952)
                     /locus_tag="ACFOAE_001291"
     CDS             complement(7707..7952)
                     /locus_tag="ACFOAE_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884768.1"
                     /translation="MLKSIEFNSHIRNRLAAYLKGRGLDFQTAMREEKGNKEIASIIH
                     GGLPVLVRKLYSEQKMQKFFWEKRDLIADYISRRMQG"
     gene            8064..8492
                     /locus_tag="ACFOAE_001292"
     CDS             8064..8492
                     /locus_tag="ACFOAE_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopD family protein"
                     /protein_id="HFC6884769.1"
                     /translation="MMFSWFKLFHLFFVISWFAGLFYLPRIFVNMAMIDAPRGNPEYV
                     RLSDMAVRLYRFMSPLGFGAVVFGAAIPFAAGWWGSGWVHVKLCLGLMLLAYQLYCGV
                     LLRRFQNYSNTFSHRWYRVFNEIPVLLMVAALYLVVFKPF"
     gene            8504..8980
                     /locus_tag="ACFOAE_001293"
     CDS             8504..8980
                     /locus_tag="ACFOAE_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFC6884770.1"
                     /translation="MPIEIERRFLIGNDNWRQYADEPLLLRQGYLSVEKERTVRVRIA
                     GKRAWLTLKGYISEISRSEFEYEIPLADAEKMMETMCPFKMEKRRYPVRWGGSLFEVD
                     VFLGENAPLVVAEIELPDENADFDRPDWLGREITADGMFTNAYLSRHPFSSWKNAV"
     gene            complement(9330..9818)
                     /locus_tag="ACFOAE_001294"
     CDS             complement(9330..9818)
                     /locus_tag="ACFOAE_001294"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFC6884771.1"
                     /translation="MLKLTLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIM
                     GRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQ
                     IYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGTSYAFVHYL
                     RY"
     gene            complement(9886..10941)
                     /gene="aroG"
                     /locus_tag="ACFOAE_001295"
     CDS             complement(9886..10941)
                     /gene="aroG"
                     /locus_tag="ACFOAE_001295"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HFC6884772.1"
                     /translation="MTHHYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQE
                     ISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRT
                     TVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLIS
                     WGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAG
                     HSAIVHTGGNPDCHVILRGGKEPNYDAGHVSEAAEQLRAAGVTDKLMIDCSHANSRKD
                     YTRQMEVAQDIAAQLEQDGSNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEE
                     LLALLAGANKKRMARAS"
     gene            11608..11865
                     /locus_tag="ACFOAE_001296"
     CDS             11608..11865
                     /locus_tag="ACFOAE_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884773.1"
                     /translation="MTTQMCASRDVSKSAKGWSVGIGLNVGKQLTDSVGLEFDPYYRH
                     KTICKPREIVLDGDKTKMGRSKSNEYGFRVTATFYSQLKSK"
     gene            complement(11847..>12060)
                     /locus_tag="ACFOAE_001297"
     CDS             complement(11847..>12060)
                     /locus_tag="ACFOAE_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003755953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6884774.1"
                     /translation="YILDNARFHRMGVLREMAEKLGHKVLPLAPYSPELNPIEKVWAN
                     IKRYLQTVLSDYARFDDALLSYFDFN"
BASE COUNT         2770 a         3335 c         2966 g         2989 t
ORIGIN      
        1 cgtcgccggt tcaaacttca atccgattgc gacacggtaa ccggtatgcc gcgcaagcgc
       61 gcaagcagcg cgtccgcctt ctgtttctgc gcggcaaacg ccgccttgtc cgcctgcgtc
      121 aattcgggtg tcggcaatgc gactgaaaca ggattaacgg gctgcccgtt gatgcgcgcc
      181 tcgtaatgca ggtgcggccc ggtcgaacgc ccggtcgaac cgacaaaacc gatgacctcg
      241 ccgccgcgca cattgccttg tgcctgcgaa aacgcgctca agtgcgcgta cagcgtttcc
      301 acgccgttgg cgtggcgtat catcaccgcg ttgccgtatc cgcccttccg gcctttaaag
      361 gtaatcacgc cgtcggcgga agccctgacc ggcgttccct gcggtgcggc ataatcgatg
      421 cccgtgtgca gccgccatgt gtgcaggatg gggtgcatac ggtagccgaa cggcgaagaa
      481 atgcgcgtat agaccagcgg ctcgatgttg aagccgcctt tttcctgcaa caccctgccg
      541 tcttcatcat aataattgcc gccccctccg ccttccttgt ccgaacggta atagaatgcc
      601 tgatgccttg tgccgccctt aacgacttca gccgccaaaa tatcgcccgc cgccacctgc
      661 tgcccgtgga aatacaggct gtcgtacatc aggcgcacgg catcgccttc cttcaaaccg
      721 tcaaggctga agcggccggc gaaaatcccg cttaaggatt cgcggatttc gacgggcact
      781 tccgcccgcg ccagcgaacc gcgcgccgac gttttgacca cgaccgaacg cagcgtcggc
      841 aaaaccttca tatccgcctc agaagccgac cgccgccata tgccgccttt cttttccaaa
      901 gcgaccagat tgcgctcgcc gtcttcgtcg gtaaaaaact gcacttcgcg cgcgccgccg
      961 tcgccgccga ccaaaacatg aaccgactgg tcggcacgca aatgccgcaa atcggcttcg
     1021 ccgccatatt tttccgtgat tcgggcaatc tcgtcccgcg ccatacccga acgcgccagc
     1081 acgtccgcca gcgagtcgcc cggctgcacc gcctcctgca cccaatatgc cgtctgaacg
     1141 ccgctgccgc cccaagacag cggcggcaga ttttgttcca cgcgctgcgg tctgacgcgc
     1201 tccgtcctct ctgtcgaagc aatgtatgcc gccgacacca aaataatcga aacggcaagc
     1261 gcacgcagcg cgtatttccg atgttttgcc gaaagtggga agacagccat attgttcctt
     1321 tttgacggcg tttgcgccga atcctctata atgttgcgcc tgacctgcat ttctgaaacg
     1381 tcaaacgatg aaactcaccc tcgccctccc ctcgctcaat ttggatgaag acgaaatccg
     1441 aatacctcta tgcctgcccg ccttcaacaa aatcctgcaa tacggctcgc tgcaccgcca
     1501 aagctgcacg gcttcggcat tttacgcgcg ttatttgtgg tgcggcagac tggcggaacg
     1561 cgcggcgcaa agcctgaata tgccgtctga agccgtcgcg ctcgccacgc ccgtctggca
     1621 aaagatgggg atgcatcagg caaatgtgct aacggcggaa tatctgaacg tcggtacgga
     1681 tgaagcggaa cggctctgcc gcgacctgtc ggcgttttac ggcgacattc catggcgttt
     1741 cgttcccgtc ctgcccgaat tatggctggt ttcccttcct tgcgcgtacc gctggggcgc
     1801 gaagcccgtt ttggacttgg gcggattgtt gggcgcggac gatcagccgg acggagaaga
     1861 tgcgttggaa tggctgcgcg tccaaaccga aatccaaatg tggctggcgg cgcaccccgt
     1921 caaccataac cgcaaaaaac gcgggctgcc cgagttgaac ggcttatggc tttgggacgg
     1981 cacaaacggc ggcgcgcaag gcggcacact tttcgccgat acggtttgga gccgtttcca
     2041 ccccgaccgc cgcgcattgc ccgacaactt ccgcgcctat gaagaaacgg cggcacacct
     2101 gcctgacacg caccatatcc tgtttatgga cgatttgcgc ctgaccgccc tgacagggga
     2161 cagggagcgg tatgcggcaa tattgcagca gtgggaagaa cgctggttcg caccgcttta
     2221 cgaagccgtc cgtaccggca aaatcaaacg gctggacatc accacggacg gacaacacgg
     2281 cggtacgctg accttcaaac ccgccgacag gtggaaattt tggcgcggcg cgaaaacctt
     2341 tgacggaatc tggtgaaccc gcctgccgca accgcgacaa tgccgtctga agcccgaatc
     2401 gggtttcaga cggcatttta cctcgcatcg ccgttatgcc ggaaaaaccg gaatgcgttt
     2461 ccgcacacgc ggcggcacgc aaagcaccgc ccgaaagccg ccgatgcccg ccgtgatacc
     2521 gccgccggca gggtttcctc cgaaaaggaa cagcaatcag aacgttttat taaactcgac
     2581 aaacgcccga tttttctcgt attcgttgaa cacatcgtta ctccgcgttt cgcggtgcga
     2641 caacgtcagg cgcggcgtga tgcctttgaa atgcaatgcc cggtgccaaa ggctcaagga
     2701 tgtgttcaat tctttatccc tgcgcctttc ccctttaaaa ccgctgaaaa agccgggttt
     2761 ttcataatgc cgtttcgccg cgccgaggcg caacagcgaa gacaggccgc tgccgcccca
     2821 ttcctgcccc caggcaaagc gcaggccgta acggttgaaa ttgtcgcccc ggtcggcggg
     2881 gttgcgctcg cggtaaaaat ccaaaccgcc catccaatat tggcgcgcat tccggtaaaa
     2941 caccagcgaa ttggaaattt gcaaatgggt attgtcggaa cgcgcccggc gcgtattctt
     3001 caaacgcccc cactccgccg aagacaacgt ttgccatttc ggggtttgcc aacggttgaa
     3061 ataaaggcgt gcgccgttgg tgtaagaata agcgtcgttg ccgtaggtgc ggcgttcgtg
     3121 gaacactgcc agcccggcat ctttgcgccg gtcggcaaaa ccgatgccgc cggaaacgcc
     3181 tgccgtcata tcgttgaatt tcttattccc cggataaacc ctgccggaca cgtcgccgcc
     3241 cgccgtcgtg taccagccgt ttttcagcga ccattttttc tccgcgccga gccggtaatt
     3301 gaccgccgtg ccgtccacct gtttcgggaa agtccatttg ccgtactgct gccgtttcgg
     3361 ggcttggttg atattgtgtt cgcgggtaac gctgaagccg ccatttacct tccacgcatc
     3421 gcgttcgcgc aatgccttgc ggtacagctc gacctgctcc atcagctgcg gcggcaggtt
     3481 ttccgccttc aggcggtcga actggtctgc cgccgcctcg ttctgcctgt tgtcaaacaa
     3541 tgccgccgcc aaacgcatac ggacggcggg cgcgtcgggt tgggcggcaa tcaattcccg
     3601 gtaatgggaa atcgcctcct tcaccctacc gtctgcctgc gccaaaatcc cttgtgcata
     3661 aagtgccaac atcttatcct gctgcgcctg ttgtaggtaa atcggcaaaa taacgcggat
     3721 accggcaata ttgtttgaga ccactgcgga atacatcgcg cgggacaaca attcgggact
     3781 tttcagcagg gtttctccgt caatctgcaa aacttttcct ttttcccgca cctgccccgg
     3841 taccttctcc ctgtcgattg gtttgacctc cgcttcatga agcctgaact cgggacggct
     3901 tctcaaatcc ggttcgcgcg gtgtttcttc ggcatatgcc gcacttgcca ataaaggcag
     3961 cagcagcatc catctgtttc gtgcaggcat aaatgtcttc ccacaaaaat aaaaaataac
     4021 cattatcaat cggcggattg tatcagtttt ttatgccgct gttccaaacc ctgccgcccg
     4081 atgccgcgac aatgccgtct gaagccagaa tcgggtttca aacggcggca aaaaaccggc
     4141 ggttttccgc cggtttcatc attatgcccc gcccttcggg gcagcagggt tcggattggt
     4201 ttgcggggcg gcgtgcggtg ccgtgccggt gtgccgcctg tacgtcaaaa catttcccga
     4261 cgcatcaaaa cagccatttg agcgacaatg cggcttcttt gtcgccgtcc gtccttttgc
     4321 cgtatccgat gcgtgcggac atatgacctt tccaaccggc ttcaatgccg aaccgccctt
     4381 cgagcgccgt cctgcctgcc agcgtctgtt tttcgccgtc catttccacg ccgaaagatt
     4441 ttgacctgtg caaaacatta aaagcggcaa aaggctgaag attgacacca ttacgcaaag
     4501 caaaacggtt ttttgcccga atgccggcgc ggctttgcca ctgaccgctg ccgagcagtc
     4561 cgacccccgt cccctcgctg tcggtaaagc cgccgtttac gcccaagtag gtaaactgcg
     4621 cctgcggttg caggtaaaac cgcacattat tgccttttcc gacaactcct tccgccacaa
     4681 gcgtgttgta gccgccttcg acagaagccg tccaaccttt ggttttgtag cgttccgcac
     4741 ggttttcatc attgatgcgg tgtttgaaac gttggtattg caaccagccg tccaaatacg
     4801 cacccgtttg tttatcgcgc aactgatgcc acgcagcata aacacccccg ccataaccat
     4861 gcaaatcact gcctgccgca ccgcctttgc tgttaactga tgcgtgctgg ccgaccctgc
     4921 cgcccatcac gccgattgcc agccggctgc cttcattttg ccgtacaaac acctcgccgc
     4981 cgatttgcac gcctttgcgc cgcccgtccg cagccgcgcc accccgtata ttttgacggg
     5041 acggatcggc ggcatacacg tcgtcgcccc tgtcggcggc acgcagccca aacaaagtat
     5101 ttgccgcata agcctgttgg gcatataaaa ccgcttccgc ctcggggata gccaaacgct
     5161 gcacgcccaa gcaaaatccg ccttcgcatt gcttgagcaa taattcgtac agtccctgcc
     5221 ggtaattttg tttaaacgca aacgaaccgg aatccgccgt ttttgccgca atcagtttgc
     5281 gcccgtcgag cgttttcaga ttttccggcc ggcgttccaa aaccacgccg gattgtccgc
     5341 tgactttgtc ttcaaaggtc agggcgggtt cgtccgactc ccgcacgtcg tagccgaaca
     5401 ggaaatccgc gccgcccgca taatccttat ggacggtcag tttttcatct ttcgtgttca
     5461 ggcggatgcg ggcattatcg gaagtttcca gcgtatggat gtcggaatgg cggcgcggtt
     5521 cccaaaggga atctttcagc gtcatcttgg tcagttccaa cacctgtccg gcgacgtggg
     5581 atttgttttc gattttgacg tgtaattttt tattgaagat gttgttgaga ctagtctgtg
     5641 atgtattact atgaggagtg agtacggaat cttctaccaa tttattaatt aaatcggggt
     5701 ttttctgttt gagtatacta aattttggtc caagctgttc tatatacgcc tcctcagtcc
     5761 gttttttatt ttcttcccaa gcttcgggtc ttgttttgta taaatcctgt aattgcttct
     5821 taaccgcatc ctttaaatta tccccgtaag tatctgtaat atatttctta acaacgggca
     5881 tattatcgac ggcgagtatg ccgctattgt agtttttacc ttggatattg atttcgtcat
     5941 acccatattc ggatgaattt tgatcggttt taccgctgga aaaataatgg gaagtgccgg
     6001 gtttcggctt gtctgaaaat gaaaaatcgg catcgtcgcc gattttggta gaacgagtat
     6061 ttgaaccaag ctgagctctg aacataccga agcaatcaaa agatatgctg cacggaccgc
     6121 gccaaacgtg ggaatctctg ttttccgccg cttctaaaat gaatcgcgga agaacttcag
     6181 gatcatattc atccgcaccc caagcatatg gcgtgcaaaa cagcgataaa acagataatg
     6241 ttaatagatt aacccgaccg cttgcttgct tgcttgcttg cttgcttgct tgctttcagt
     6301 gtcatgagaa attttccttt gtcaagtgtt aaaattataa tgattatata ctacatcgca
     6361 ctacatcgca atgaaaaatc aggaaaaact aaaaacccct ccgccgtcat tcccgcgaaa
     6421 gcgggaatct agaattttaa tgccgcaaga atttatcaag gatggtcggg gtttaaaggt
     6481 ctggattccc gcctgcgcgg gaagacggtt tagaaatcac ccgaaacaag aaaaagaacc
     6541 gaaaccgaac aagccggatt cccgcctgcg cgggaatgac gggatttcag gttactgttt
     6601 ttgattttct gttttgtgga aataacggga ttttggatga tgtgcattta tcgagaaaac
     6661 taaaaaccct ccgccgtcat tcccgcgaaa gcgggaatct agacctttcg gtgcggaaac
     6721 ttatcggata aaacggtttt ccctgcatcc tggattccca ctgtcgtgcg aatgacggga
     6781 tataggtttc actacggacg tgttcagatt accgcctgcg cgggaaggac gggatttcag
     6841 gttgctgttt ttgattttct gtttttgtgg gaataacggg actttggatg atgtgcattt
     6901 atcgggaaaa caaaaaaccc tccgccgtca ttcccgcgaa agcgggaatc tagaatttta
     6961 atgctgcaag aatttatcgg ggatgaccga ggtttgaagg tctggattcc cgcctgcgcg
     7021 ggaatgacgg tttagaaatc acccgaaacg agaaaaagaa ccgaaaccga acaagccgga
     7081 ttcccacctg cgcgggaatg acgggatttc aggttactgt ttttgatttt ctgttttgtg
     7141 ggaataacgg gattttggat gatgtgcatt ttcgggaaaa ctaaaaaccc tccgccgtca
     7201 ttcccgcgaa agtgggaatc tagaatttta atgcggcaag aatttatcgg aaaaaactga
     7261 agtttaaaga cctagattcc cgcctgcgcg ggaatgacgg tttagaaatc acccgaaacg
     7321 agaaaaagaa ccgaaaccgg acaagtcgga ttcccgcgcg ggcgggaagg acggaatttc
     7381 agattgttgt ttttgatttt ctgttttgtg ggaataacgg gattttggat gatgtgcact
     7441 tatcgggaaa actaaaaacc ctccgccgtc attcccgcga aagtgggaat cccgaatttc
     7501 aatgccgcaa gaatttatcg gagatggacg ggatttaaag gtctggattc ccgcctgcgc
     7561 gggaatgacg gtttagaaat cacccgaaac gagaaaaaga accgaaacca gacaagtcgg
     7621 attcccgcgc gggcgggaat gacgataagc gtaatttcaa tctgccatat tgtcttttca
     7681 cttgcctgaa aacagatttc agccgcctat ccctgcatcc ggcggctgat gtagtcggca
     7741 atcaaatccc gcttttccca aaaaaatttc tgcatttttt gttcggaata cagtttgcga
     7801 accagtacgg gcaggccgcc atgaataatt gaggcaattt ctttgttgcc tttttcctcc
     7861 cgcatcgccg tctgaaaatc caaacccctg cctttcagat atgctgcaag gcggttgcgg
     7921 atgtgggaat tgaattcgat ggatttgagc attttgcctc cgttttgcgg taaggattta
     7981 ttcgatttgt ttatccgcct gattttatca cgtttcccaa gcggtttgcc tgtacaatac
     8041 cgcttttcgg cagggtgtgg gcgatgatgt tttcttggtt caagctgttt cacttgtttt
     8101 ttgtcatttc gtggtttgca gggctgtttt acctgccgag gattttcgtc aatatggcga
     8161 tgattgatgc gccgcgcggc aatcccgagt atgtgcgcct gtcggatatg gcggtgcggc
     8221 tgtaccgttt tatgtcccct ttaggtttcg gtgcggtcgt gttcggcgcg gcgataccgt
     8281 ttgccgccgg ctggtggggc agcggctggg tacacgtcaa actgtgtttg ggcttgatgc
     8341 ttttggctta ccagttgtat tgcggcgtgc tgctgcgtcg ttttcagaat tacagcaata
     8401 ctttctcaca ccgctggtac cgcgtgttca acgaaatccc cgtgctgctg atggttgccg
     8461 cgctgtatct ggtcgtgttc aaaccgtttt gacggagcat cttatgccga tagaaatcga
     8521 acgccgtttt ttgattggaa acgacaactg gcggcaatac gccgatgagc cgctgctgtt
     8581 gaggcagggt tatctgtctg ttgaaaaaga acgcaccgtc cgtgtccgca ttgccggaaa
     8641 acgggcgtgg ctgacgctga aaggctatat ttcggaaatc agccgcagtg agtttgaata
     8701 cgaaatcccg cttgccgatg cggaaaagat gatggaaacg atgtgcccgt ttaagatgga
     8761 aaaacggcgt tatccggtca gatggggcgg cagcctgttt gaagtcgatg ttttccttgg
     8821 cgaaaacgcg cctttggtcg tcgcggaaat cgagttgccc gacgagaatg ccgattttga
     8881 ccgtccggac tggctgggac gggaaatcac tgccgacggt atgtttacca atgcttattt
     8941 gagcaggcat ccgttctcaa gctggaaaaa tgccgtctga aacggcttca gacggcattc
     9001 tccgacaacc atcgcaaatc caaagacagc ctctatatcc ttatttctgc tttctttgtt
     9061 ccattattcc caataaatcc ccataaccta aaatctcgtc attcccgctc aggcgggaat
     9121 ccggttcttt aaacttcggt tttttccgat aaattgcttt agcttttcgt ttccggattc
     9181 ccgcttttgc gggaatgacg atggaagatt gttgttattt cggataaatt accctaactt
     9241 taaaatcccg gattcccatc ttcgggggaa taacaatatt ttctatttca gcccatcatt
     9301 tgcgggggat tttatagaga gtttatattt caatatctca aataatgcac aaaagcatag
     9361 ctcgtgcctt tgctgctgac gcggcgttcc gtccgctctg cttctttcca atgcgtccgg
     9421 tctattgcgg ggaaaaatgc atctccttcc acagacaaat ccacttcggt tatccgcaaa
     9481 tcggtcgcca atggcatcgc ttgtccgtat atctgcgcgc cgcccataat gacggcttct
     9541 tccgcgcctg cgcacaatgc caatgccgcc tccaaacttg ccgccgtttc cgcgcctgcc
     9601 gcgcaataat ccgcctgccg gctgatgacg atgttcctcc gtccgggcag gggtttgacg
     9661 ggcagggatt cccacgtttt ccgccccata atgacgggtt tgcccaaggt ataggctttg
     9721 aaaaatgcga aatcttcggg gatgtgccaa ggcatagcat tgcccgcccc gatgcacagg
     9781 ttttccgcac acgccgcaat tagggttaat ttgagcatat ttcctccaca aaaatgccgt
     9841 ctgaacgctt cagacggcat tttatgacat tctgcgtcaa aaatctcaac tggcgcgcgc
     9901 catacgtttt ttgtttgcac ctgccaacaa tgccaacagt tcttcagtcg cgccccaacc
     9961 gatacacgca tcggtaatgc ttttgccgta cacttccggc ttatcctgtc tgccttcgac
    10021 caaatggctt tccaccatca cgcccataat attgctcccg tcctgttcca attgggcagc
    10081 aatatcttgt gccacttcca tctgccgggt gtaatccttg cggctgttgg cgtggctgca
    10141 atctatcatc agcttatcgg ttacccctgc cgcacgcagt tgttccgccg cctcgctgac
    10201 gtgtcccgca tcataattcg gctcttttcc gccgcgcaaa atgacatgac agtcgggatt
    10261 gccgccggta tggacaatgg cggaatgtcc ggccttggtt acagacaaga aatgatgcga
    10321 atggctcgcc gcaccgattg cgtcgatggc aatcttcaaa ttgccgtccg taccgttttt
    10381 aaagccgacg gggcaggaca gcccgcttgc caattcgcgg tgaacttggc tttcggtcgt
    10441 ccgcgcaccg attgcccccc aagaaatcaa gtccgcataa tattgcggcg taatcatatc
    10501 caaaaactcg gtagaggcag gcatacccat attgttcagc gacaacaaca ggctgcgcgc
    10561 ctgacgcaaa ccgaaattga tatcgaacgt accgtccaaa tgcgggtcgt taatcaaacc
    10621 tttccaaccc accgtcgtcc tcggcttctc gaaataaacg cgcatcacaa tcaaaagctc
    10681 gttttcatac tgcttgcgga gtttcaacaa acgctccgca tattccaacg ccgctttcgg
    10741 atcgtgaatc gaacacggcc cgataataac caacagccgc ttgtccctgc cgtgaaccaa
    10801 atcggaaatt tcctgacggg tgcggtgaac caagcccgaa gcctctttgg aaatcggcaa
    10861 ctcgtaaaga tgggcaatcg gcggcaacaa ctctttaact tctttaatct taatatcgtc
    10921 tgtggggtaa tggtgtgtca tcttgcatct ttcctgatgg ttttttatac gcggcttagg
    10981 ttacatcgtt taccttgcac aaacaagtgc aacatattac tacaaagcta ttttatttca
    11041 aaataactga tatatctttt ttcatagatt ttaaatttca tatttttaat attttaggaa
    11101 ttttattcca aagaaaaaga aacagattga taaaaacaat acccgccatt cattcggaca
    11161 aaaccgcacg gaacatccgt tttcccattt ccacgacaat ccggtacaga acaccccgct
    11221 gccgattccg cctgcacatc cggcaaaatt tcatacacaa ggaaaatgtt gaaaacaaaa
    11281 agaactcatt gcttgaaaaa agatttaatg ggaatgcggg tatttcccac actttttcca
    11341 tttatttatc ctcattatag gaagaaaaac atgaaaaaac cctgcttgca ctctcacttg
    11401 cagccgtgtc cgccgttacg gtagccgata ttcccgagtc taacggcaaa ggcaaagcca
    11461 tcatcggcga taaggaaaaa caccgttacc aagcatgaaa accttgcttt gaaagtccat
    11521 ggcgaaatcc gccaagattt gggggacgga tgatccctaa ccccttgggt ggatgcatat
    11581 gcagatttgc gcggcaaaac caaagtgatg acgacccaga tgtgtgcttc ccgcgatgtc
    11641 agcaaaagcg ccaaaggttg gagtgtcggt atcggtctga atgtaggcaa acagttgacc
    11701 gacagcgtcg gtctcgagtt tgatccatac taccgtcaca aaacaatctg caaaccccgt
    11761 gagattgttt tggacggcga caaaaccaaa atgggccgct ccaaatccaa cgagtacggc
    11821 ttccgcgtaa ccgcaacgtt ctatagtcaa ttaaaatcaa agtaggacag tagtgcatcg
    11881 tcaaatcggg cgtaatcaga caaaacggtt tgcagatacc gcttaatatt cgcccacact
    11941 ttctcaatcg ggttgagttc aggtgaataa ggtgcaagag gcaatacctt atgtcccaat
    12001 ttttccgcca tttcccgtaa gacacccata cggtgaaatc gcgcattatc taaaatatag
//
LOCUS       DAXIDM010000056        11910 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000056 DAXIDM010000000
VERSION     DAXIDM010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 11910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11910
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.056"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            79..1263
                     /gene="coaBC"
                     /locus_tag="ACFOAE_001298"
     CDS             79..1263
                     /gene="coaBC"
                     /locus_tag="ACFOAE_001298"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0015941 - pantothenate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HFC6884775.1"
                     /translation="MGKHILLGVTGSIAAYKSCELVRLLKKQGHSVTVVMSRSATEFV
                     SPLTFQALSGNPVLTDTHGGNCSNGMEHINLTRNADVFLIAPASMNTVAKICNGVADN
                     LLTSLAAARKCPLAIAPAMNVEMWLNPANQRNIAQLVSDGITVYMPGLGEQACGENGM
                     GRMPEPAELLDLLPDLWTPKILRGKKILITAGATFEAIDPVRGITNTSSGKMGVALAR
                     ACRAAGAEVSLIHGQLQTALPFGISDTVQAVSAEDMHRAVHRLIEKQDAFISVAAVSD
                     YKVKNKSTQKFKKDKNAKPLSIELDENPDILASIASLPNPPFCIGFAAETENVMAYAR
                     EKRIKKKIPVIVANDVSIAMGKPTNRITIIGDDGELSFPETSKDEAAMQIVERLAVYL
                     NK"
     gene            complement(1330..3486)
                     /locus_tag="ACFOAE_001299"
     CDS             complement(1330..3486)
                     /locus_tag="ACFOAE_001299"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFC6884776.1"
                     /translation="MPVPQPTAPYDPLTAEARALLFHTASYLKPEEQAELEKAVAYAF
                     RAHDGQTRKSGEPYITHPIAVATQLALWHMDIQGLCAGVMHDVLEDTGVTKGEMAAVF
                     GNTIAEMVDGLSKLEKLKFEDHAEHQAESFRKLILAMTKDVRVIVVKLADRLHNMRTL
                     GSMRPDKRRRIARETLEIYAQIANRIGLNNAYQELQDLSFQNLHPNRYETLKKAMDKS
                     RKNRQDVVGKVLRAFGQRLVGANIEAKIKGREKNLYGIHQKMMAKKLRFAEVMDIYGF
                     RVIVNSIPACYAALGALHTLYQPKPGRFKDYIAIPKSNGYQSLHTTLVGPYGLPIEVQ
                     IRTKEMDAVAEGGIAGHWSYKSYSKTVDQAVLHTNRWLKNILDLQASSANAIEFLEHV
                     KVDLFPNEIYILTPKGKILTLPKGATPVDFAYAVHTDIGHKTVAARINNIMMPLRTKL
                     KTGDSVEIITSEHAKPNPAWLNFAVSGRARSAIRQYIKNLNRHDAVVLGESLLQKALS
                     SLLPKDVLLSDGIKEKYLADLNDKQTSFEEVLYNVGMGHTLPVYVAMHIAELAGEHFG
                     SEVRLSSIKVDGQESGHIHFAECCHPVPGDSIRLLLVKGKGMIIHRDSCPTLLKSDPE
                     QQLDADWENMNGQNYRVGLQVQSEDSHGLLALMAQAISDSGADIESVETPSKSQSGTE
                     GFVEFKFLLKVKNLNQLNQIIQNLHSIPYIRKVIRS"
     gene            complement(3579..3785)
                     /gene="rpoZ"
                     /locus_tag="ACFOAE_001300"
     CDS             complement(3579..3785)
                     /gene="rpoZ"
                     /locus_tag="ACFOAE_001300"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFC6884777.1"
                     /translation="MARITTEDCTGKISNHFDLTLVAARRARQLENGNTPLVDDVRNN
                     KPTVTALREIAAGHIGTELLTRNK"
     gene            complement(3844..4461)
                     /gene="gmk"
                     /locus_tag="ACFOAE_001301"
     CDS             complement(3844..4461)
                     /gene="gmk"
                     /locus_tag="ACFOAE_001301"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFC6884778.1"
                     /translation="MSAYRKGNIFIISAASGTGKTTLVSRLLANHNGLRVSVSHTTRP
                     PREGEVNGVHYHFVSKEEFESLIAQEAFLEYADVFGNYYGTSAEGVNALAAAGYDVIL
                     EIDVQGAAQVRNALPEAVGIFILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQ
                     SVLFDFVVVNDDLARAEEDLRHIVNACRLKRSRQLGFIADLLENS"
     gene            4589..5188
                     /locus_tag="ACFOAE_001302"
     CDS             4589..5188
                     /locus_tag="ACFOAE_001302"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFC6884779.1"
                     /translation="MALKTSNLEHAMLVHPEAMSVGALADKIRKIENWPQKGILFHDI
                     TPVLQSAEYFRLLVDLLVYRYMDQKIDIVAGLDARGFIIGAALAYQLNVGFVPIRKKG
                     KLPFETVSQSYALEYGEAAVEIHTDAVKPGSRVLLVDDLVATGGTMLAGLELIRKLGG
                     EIVEAAAILEFTDLQGGKNIRASGAPLFTLLQNEGCMKG"
     gene            complement(5234..6022)
                     /locus_tag="ACFOAE_001303"
     CDS             complement(5234..6022)
                     /locus_tag="ACFOAE_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFC6884780.1"
                     /translation="MNPKIVFFDIDDTLYRKYTDTLRPSVKTAVAALRGKGILTALAT
                     GRSLATIPEKVRDMMAETGMDAVVTINGQFALLHGKTVREVPMDAGLMGRVCAHLDGL
                     GMDYAFVGGEGIAVSALSECVCRALQHIASDFFADKDYFSSKPVYQMLVFAEENEMPP
                     WSDIVEREGLKTVRWHEEAVDLLPAGMSKTDGIRSVVGALGLEMADVMAFGDGLNDVE
                     MLSEVGFGVAMGNGEQAAKEAAKYVCPSVDEDGVLRGLQDLGVI"
     gene            6347..7702
                     /gene="yegQ"
                     /locus_tag="ACFOAE_001304"
     CDS             6347..7702
                     /gene="yegQ"
                     /locus_tag="ACFOAE_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HFC6884781.1"
                     /translation="MKAPELLLPAGGLERMRAAYDYGADAVYAGSPRYSLRARNNEFA
                     KLDVLEQGIKEAHERNKKFFLTVNTLPHNSKLKTFVSDMEPLIAMKPDALIMADPGLI
                     MTVREKWPEMPIHLSVQANTTNYWGVKFWQNIGVERIILSRELSMEEIAEIRQQCPDI
                     ELEVFIHGALCIAYSGRCLLSGYFNHRDPNQGTCTNSCRWDYKVHNATESDAGDAQLL
                     QGFNFEKAQEEANQNFEGINGQKRHPYADKVFLIEESNRPGEMMPIMEDEHGTYIMNS
                     KDLRSIEVVEKLAKIGVDSLKVEGRTKSLYYVARVAQSYRKAIDDAVAGRPFDYSLLS
                     ELEGLANRGYTSGFLERHQTQDYQNYLTGHSIAKQSQYVGHVTEIDAEGWATVEVKNR
                     FAIGDSLEIIHPSGNQTIKLEQMARKGQPVDVAPGNGIQVKIPNMRGKEKALIARVLN
                     P"
     gene            7836..8312
                     /locus_tag="ACFOAE_001305"
     CDS             7836..8312
                     /locus_tag="ACFOAE_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease"
                     /protein_id="HFC6884782.1"
                     /translation="MLAACQSGSAPKNAHTASPGTPAGESCKVIRGDTAGSGKNIIYR
                     CCNGQAAINAAIADGVLESGIPVSFGGGGVPVANGRNLVTRQAANGVGKSDSEACERA
                     LINAARKFQQTAGKLGGRSVTGFHSYFDKQPLQGGQYDCQAGSFHVRVVMRANVVR"
     gene            complement(8564..8905)
                     /locus_tag="ACFOAE_001306"
     CDS             complement(8564..8905)
                     /locus_tag="ACFOAE_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFC6884783.1"
                     /translation="MPQVKLVITRPAQSDLVRIYNFLNDLGAEHQANTVMRLLKNSFV
                     STQGSPGNGKPYDLSVAGETLQNVREVIVPYGKSGYSYLFWHDKSDRQILILTVRHFR
                     ENAYRLNFPFL"
     gene            complement(8893..9180)
                     /locus_tag="ACFOAE_001307"
     CDS             complement(8893..9180)
                     /locus_tag="ACFOAE_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884784.1"
                     /translation="MMLTNQEVTGVKLGYRKAVLQELARDFGGSVHSIVLDAVDGHIE
                     RLKAKQAYDKRAMQAFQDYQETGLHITLNEFADWVDGLGGDEPKDMPECRK"
     gene            9250..9360
                     /locus_tag="ACFOAE_001308"
                     /pseudo
     CDS             9250..9360
                     /locus_tag="ACFOAE_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212660.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease"
     gene            complement(9550..10878)
                     /locus_tag="ACFOAE_001309"
                     /pseudo
     CDS             complement(9550..10878)
                     /locus_tag="ACFOAE_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250318.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
     gene            complement(10946..11086)
                     /locus_tag="ACFOAE_001310"
     CDS             complement(10946..11086)
                     /locus_tag="ACFOAE_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884785.1"
                     /translation="MTIPFKPSLLAMASVLALSACISGGGDAPAVKSSETPSNKVATP
                     PH"
     gene            complement(11219..11848)
                     /locus_tag="ACFOAE_001311"
     CDS             complement(11219..11848)
                     /locus_tag="ACFOAE_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biliverdin-producing heme oxygenase"
                     /protein_id="HFC6884786.1"
                     /translation="MSETENQALTFAKRLKADTTAIHDSVDNLVMSVQPFVSKENYIK
                     FLKLQSVFHKAVDHIYKDAELNKAIPELEYMARYDAVTQDLKDLGEEPYKFDKELPYE
                     TGNKAIGWLYCAEGSNLGAAFLFKHAQKLDYNGEHGARHLAPHPDGRGKHWRAFVEHL
                     NALNLTPEAEAEAIQGAREAFAFYKVVLRETFGLAADAEAPEGMMPHRH"
BASE COUNT         2886 a         3251 c         2807 g         2966 t
ORIGIN      
        1 tccaaaacgg taactaatgt atccgtactt tgttatagaa tggatgctgt tttttcttcg
       61 taattagaaa ttgtcaaaat gggcaaacat attcttttag gtgtaacggg cagtattgcg
      121 gcgtataagt cttgcgagtt ggttcgtctg ctgaaaaaac aggggcattc ggttacggtg
      181 gttatgagcc gctcggcaac tgaatttgtt tctccgctga cttttcaggc tttaagcggc
      241 aatcctgtcc tgaccgacac gcacggcggc aactgttcaa acggtatgga acatatcaac
      301 ctgacccgga atgcggatgt ttttctgatt gcgccggcaa gtatgaatac cgtggcaaaa
      361 atctgtaacg gcgtggcaga taacctactg accagtctgg cagccgcacg gaaatgtccg
      421 cttgccatcg ctcccgcgat gaatgtggaa atgtggctca accctgccaa ccaacggaat
      481 atcgcacaac tggtttcaga cggcattact gtctatatgc cgggcttggg cgaacaggct
      541 tgcggagaaa atggtatggg aaggatgccg gaacctgccg aattgctgga tttgcttccg
      601 gacttgtgga caccgaaaat tttaaggggc aagaaaatct tgattaccgc aggtgcgaca
      661 tttgaagcca ttgaccctgt caggggcatc acaaatacct ccagcggaaa aatgggggta
      721 gctttggcgc gggcgtgccg tgccgccggt gcggaagtca gcctgattca cggacagctt
      781 caaaccgcgc tgcctttcgg catatccgat acggttcaag ccgtcagcgc tgaagatatg
      841 catcgcgcag tgcatcgttt gattgaaaaa caagatgctt ttatttctgt tgccgccgtc
      901 tcagactata aggttaaaaa caagagtacg caaaaattca aaaaagataa aaatgccaaa
      961 ccgttatcca tcgaattgga tgagaacccc gatattttgg cttctattgc ctcattgccg
     1021 aacccgccgt tctgcatcgg ttttgccgct gaaacggaga atgtaatggc atatgcacga
     1081 gaaaaacgta ttaagaaaaa aataccggtg atagttgcca atgatgtttc aatcgcgatg
     1141 ggcaaaccga ccaaccggat taccattatc ggggacgacg gggaactgtc ttttcccgaa
     1201 acaagtaaag atgaagcggc aatgcagatt gttgaaaggc ttgccgtata tttgaacaaa
     1261 taagcaattg aacggataaa ccataaagcg ggttgcctgt taatcaaaag gcaacccgtt
     1321 ttacctgctt caacttctga tgactttgcg gatatatgga atactatgca gattttgaat
     1381 aatctgattc aactgattca gattcttgac tttcaataag aatttgaatt cgacaaaacc
     1441 ttccgttccc gactgggatt tggatggtgt ttcgaccgac tcgatgtccg caccggaatc
     1501 ggaaatcgct tgcgccatta atgccaacag gccgtggctg tcttccgatt ggacttgaag
     1561 cccgacacgg tagttctgcc cattcatatt ttcccagtct gcatccagct gctgttcggg
     1621 atcggacttc aacaacgtcg ggcagctatc cctatggata atcatgcctt ttcccttaac
     1681 caacagcaaa cggatggaat cgccgggaac agggtggcag cactctgcaa aatgaatatg
     1741 cccgctttcc tgaccatcga ctttaatgga actgagcctg acctcgctgc cgaaatgctc
     1801 ccctgccaac tcagcaatgt gcatggcgac ataaacaggc agggtatgcc ccatccctac
     1861 gttgtacagc acttcttcaa acgatgtctg cttgtcgttg agatcggcaa gatatttttc
     1921 cttgatgccg tctgaaagca ggacatcttt gggcagcaaa ctggacaggg ctttttgtaa
     1981 gaggctctct cccaaaacga ccgcatcgtg ccggttaagg tttttaatat attggcgtat
     2041 ggcgctgcgc gccctgccgg acacggcgaa attcaaccac gcgggattgg gtttggcgtg
     2101 ttcggatgtg ataatttcaa cagaatcacc ggttttgagc ttcgtacgca acggcatcat
     2161 gatattgttg atacgtgcgg caacggtttt gtgcccgata tcggtatgca ccgcataagc
     2221 aaaatcgaca ggcgttgccc ctttgggcaa agttaggatt tttccttttg gcgtaaggat
     2281 gtagatttcg ttcggaaaca aatcgacttt gacgtgttcg agaaactcaa tggcattggc
     2341 actgcttgcc tgcaaatcta agatattttt cagccaccgg tttgtgtgaa gcaccgcctg
     2401 atcgaccgtc ttagaatatg atttatagct ccaatgtccg gcgattccac cttcggcaac
     2461 agcatccatt tccttggtac gtatctgaac ttcaatcggc aagccgtaag gaccgaccaa
     2521 agtcgtatgc agactttgat acccgttgct tttcggaatg gcgatatagt ctttgaaccg
     2581 cccgggcttg ggctgataga gggtgtgcaa tgcgccgagt gcggcataac aggctggaat
     2641 gctgttgaca atgacgcgga aaccgtaaat atccataacc tcggcaaagc gcagcttttt
     2701 cgccatcatt ttctgatgga tgccgtacag gtttttttcc ctgcctttga ttttggcctc
     2761 tatattcgcg cctaccagcc gctggccgaa tgcgcgcaag actttgccga caacgtcctg
     2821 ccggttcttc cggctcttgt ccatcgcttt ttttaaagtc tcgtagcggt tgggatgcag
     2881 gttttggaac gataaatcct gaagctcttg atatgcgtta ttcaaaccta tacggttggc
     2941 aatctgtgca tagatttcaa gggtttccct tgcaatccgg cggcgtttgt ccgggcgcat
     3001 cgaaccgagt gtccgcatat tatgcagacg gtcggcaagt ttaacgacaa tcacgcgtac
     3061 atctttggtc attgccaaaa tcagtttgcg gaaactctcc gcctgatgct ctgcatgatc
     3121 ttcaaatttg agtttttcga gtttggacag cccgtccacc atctcggcaa tcgtattgcc
     3181 gaacaccgcc gccatttccc cttttgtcac gcccgtatct tccaatacgt cgtgcatcac
     3241 gcctgcacaa agaccctgta tgtccatatg ccaaagggcg agctgcgtcg caacggcaat
     3301 cggatgcgtg atgtagggct ccccgctttt gcgggtttgc ccgtcgtggg cgcgaaacgc
     3361 ataggcgaca gctttttcaa gctccgcctg ttcctcgggc ttgaggtagg aggcggtatg
     3421 gaaaagcagg gcacgcgctt cggcggtcag ggggtcgtaa ggtgcggtgg gttgagggac
     3481 aggcatttca gacggctttc ggaacatatt ttatttttcg tttcaaaccg tcggactgca
     3541 cggcggcaga atgtgccgac gtgcgtttcc ggcagaattt atttattgcg cgtcaacagt
     3601 tccgtaccga tatgcccggc ggcgatttcc cttaaggcgg taacggtcgg tttgttattg
     3661 cggacatcgt ccacaagcgg cgtattgcca ttttcaagct ggcgggcccg acgggccgct
     3721 accaatgtca ggtcaaaatg gttggaaatt tttccggtac agtcttcggt ggtaatacgt
     3781 gccatattat ttgctttctt tcaaaaatat ttaaaatagg aaactgggta ttttcgcggt
     3841 tttttaggaa ttttccaaca aatctgcaat aaatcccagt tgccgcgacc ttttcagacg
     3901 gcaggcattc acaatatggc gcaaatcctc ctccgcccgc gccaagtcat cattgaccac
     3961 gacaaaatcg aacaatacgg actgttcgat ttcatgcctt gccttcgaca gcctcctttg
     4021 gataacttcc cgactgtccg tcccgcgtcc gttcagacgt gcagcaagca catcgaaaga
     4081 cggcggcagg ataaagatgc cgacggcttc cggcagcgcg ttgcgaacct gcgccgcgcc
     4141 ctgaacgtcg atttccaaaa ttacgtcata gcctgccgcc gccaaagcat tcacgccctc
     4201 cgcgcttgtg ccgtaatagt tgccgaacac gtctgcgtat tccaaaaaag cttcctgcgc
     4261 gataagcgac tcaaactctt ctttagaaac aaaatgataa tgtacgccgt ttacttcgcc
     4321 ttcacgcggc ggacgcgtcg tgtgcgatac ggaaacgcgc aaaccgttat ggtttgccaa
     4381 cagccgcgac accagcgtgg ttttgcccgt gccggaagcg gccgaaatga taaagatgtt
     4441 gccttttcga taagcggaca tattttttac ctgtatattt tccagccgat tgtatcacaa
     4501 cggacactcg gtttcctatt tgccgatgcc catattttgc cgctattgtt ttgattgatt
     4561 tggcaagcgg caggctgacg gctacaatat ggcgttaaaa acatcaaact tggaacacgc
     4621 aatgctggtt catcccgaag ctatgagtgt cggcgcgctt gccgacaaaa tccgcaaaat
     4681 cgaaaactgg ccgcaaaaag gcatcttatt ccacgacatc acgcccgtcc tgcaaagcgc
     4741 ggaatacttc cgacttttgg ttgatttatt ggtttaccgc tatatggatc agaaaatcga
     4801 catcgttgcc ggtttggacg cgcgcggctt cattatcggc gcggcactcg cctaccagct
     4861 caacgtcggt ttcgtcccca tccgcaaaaa aggcaagctg ccttttgaaa ccgtatcgca
     4921 aagctacgcg ctcgaatacg gggaagctgc ggtggaaatc cacaccgatg ccgtcaaacc
     4981 cggttcgcgc gtgctgctgg tcgatgattt ggttgccacg ggcggcacga tgcttgccgg
     5041 actggagctg atccgcaaac tcggcgggga aattgtcgaa gccgccgcca ttttggaatt
     5101 taccgacctt caaggcggca agaatatccg tgcaagcggc gcgcccttat ttaccctgct
     5161 tcaaaacgaa ggctgtatga agggctgaaa accgaccctg ccgtctgaaa ccggcagggt
     5221 tgttattatg cgttcaaatc acgcccaaat cttgcaagcc cctcaacaca ccgtcctcat
     5281 caacgctggg gcaaacatat ttcgccgcct ctttcgccgc ctgttccccg ttgcccattg
     5341 ccacgccgaa cccgacttct gacagcattt ccacatcgtt caaaccgtcg ccgaacgcca
     5401 tcacgtctgc catttccaaa cccaatgccc caaccacgct tctgatgccg tctgttttcg
     5461 acattcccgc aggcagcaga tcgaccgctt cctcgtgcca gcgcaccgtt ttcaagcctt
     5521 cccgttccac aatatccgac cagggcggca tttcgttttc ctccgcaaac accagcatct
     5581 gatacaccgg tttgcttgaa aaataatcct tatcggcaaa aaaatcgctg gcgatatgct
     5641 gcaaggcgcg gcacacgcat tccgacagcg cggacacggc gatcccctct ccgccgacaa
     5701 acgcataatc catgcccaag ccatccaaat gcgcgcaaac cctgcccatc aaaccggcat
     5761 ccatcggtac ttcgcgcaca gttttaccgt gcagcagcgc aaactgtccg tttatcgtta
     5821 ccacggcatc catacccgtt tccgccatca tgtccctgac cttttcggga atcgtcgcca
     5881 aagaccgccc cgttgccaac gccgtcaata tgcctttgcc gcgcaaagcc gccaccgccg
     5941 ttttcacgga aggacgcaag gtatccgtat atttgcggta cagcgtatcg tcaatatcga
     6001 aaaacacgat tttaggattc atcacattct ctctcgcatt caaactgccg cattgtatcc
     6061 caatcaggca aatacttgat aaatccttat aaatttcccg gcaaaattga ccgcgaacac
     6121 gaaaaggcgg ataatccgcc catcctcaaa cccttttcag acggcatttg cagcaatgcc
     6181 gtctgaaaca tttttacaaa gcacacaaat catgtttcaa cacacaggac gacacataaa
     6241 gcgtcgccct atatgttgcc ctgattcgga aagggttaca cccctcccaa ataaagtctg
     6301 attctaccgc cctaaagggc ggggtttcaa ccgaaaagga aacacgatga aagcacccga
     6361 actcttattg cccgccggcg gattggaaag aatgcgcgcc gcctacgatt acggcgcaga
     6421 tgccgtttac gccggcagcc cgcgttactc actgcgcgcc cgcaacaacg aatttgccaa
     6481 actcgacgtt ctcgaacaag gcattaaaga agcgcacgag cgcaacaaaa aattcttcct
     6541 taccgtcaat acgctgccgc acaactccaa actcaaaacc ttcgtctccg atatggagcc
     6601 cttgattgcg atgaagcccg acgcgctgat tatggcggat ccgggtttga ttatgaccgt
     6661 gcgcgaaaaa tggccggaaa tgccgatcca cctgtccgta caagccaaca ccaccaacta
     6721 ctggggcgtg aaattctggc agaatatcgg cgtcgaacgc atcatcctgt cgcgcgaatt
     6781 gagtatggaa gaaatcgccg aaatccgcca acaatgcccc gacatcgaac tcgaagtctt
     6841 cattcacggc gcattgtgca tcgcctactc cggccgttgc ctactctccg gctacttcaa
     6901 ccaccgcgac cccaaccaag gcacctgcac caactcctgc cgttgggact acaaagtcca
     6961 caacgctacg gaaagcgatg cgggcgatgc ccagcttctg caaggtttca actttgaaaa
     7021 agcccaagaa gaagccaacc aaaactttga aggcatcaac ggtcaaaaac gccatcccta
     7081 cgccgacaaa gttttcctga ttgaagagtc caaccgcccg ggcgagatga tgccgattat
     7141 ggaagacgaa cacggcacct acatcatgaa ctccaaagac cttcgcagta ttgaagtggt
     7201 tgagaaactc gccaaaatcg gcgtggacag cctcaaagtc gaaggccgta ccaagtcgct
     7261 ctactacgtt gcacgcgtgg ctcaatccta ccgcaaagcg attgacgatg ccgttgcagg
     7321 ccgtccgttt gattacagcc tgttgagcga actcgaaggc ctcgccaacc gcggctacac
     7381 cagcggcttc ctcgaacgcc accaaaccca agactatcaa aactacctga ccggccactc
     7441 catcgccaaa caaagccaat atgtcggcca cgttaccgaa atcgacgctg aaggttgggc
     7501 aacggtggaa gttaaaaacc gctttgccat cggcgattcg ctcgaaatca tccacccgag
     7561 cggcaaccaa accatcaaat tggaacaaat ggcccgaaaa ggccagcctg tcgatgttgc
     7621 acccggcaac ggcatccagg tcaaaatccc caatatgcgg ggcaaagaaa aagccctcat
     7681 cgcacgcgta ttgaacccct gagccacaat gccgtccgaa ccccgttttc agacggcatt
     7741 ttgttgaatc ttacggtaca atggcaatga tttcccaccg caagcaagga tatccgacat
     7801 gaaaaaaaat cctcatactc tccgccgccg ccctgatgct ggcagcctgc caatccggca
     7861 gcgcacctaa aaacgcgcac acggcatccc ccggcacacc ggccggagaa tcatgcaaag
     7921 tcatccgggg cgacaccgca ggaagcggca aaaacatcat ttaccgttgc tgcaacggtc
     7981 aggcggcaat aaatgcagcc attgcagacg gcgtattgga atcagggatt cccgtcagct
     8041 tcggcggcgg gggcgtaccg gttgcaaacg gcaggaatct ggttacacgg caagcagcaa
     8101 acggcgtagg caaatccgac tcagaggcct gcgaacgcgc cctaatcaat gccgcccgca
     8161 aattccagca gaccgccggc aaactcggcg ggcgcagtgt taccggcttc cacagctatt
     8221 tcgacaagca gccgctgcaa ggcggacaat acgactgtca ggcaggctcg ttccacgtcc
     8281 gcgtagttat gcgtgccaat gtcgtccgtt aacatatcgg caaccaaaaa atgccgtctg
     8341 aaacattttt cagacggcat ttttaatccc cttgcctgat tgtgcggcag attcaaatcg
     8401 gggcacgcca tacttccata tccgcaccgt tcaaacatcc cgcctgcggg acggaatcaa
     8461 agcggcagtc cggttatgtt cttgagggcg attgatccga acgtgccgca acaaaccgaa
     8521 acgcattacc ccgcacaagg aaaaaccgcc aaaccaaata ccgttataaa aaaggaaagt
     8581 tcaggcggta ggcattttca cggaaatgcc tcaccgtcaa aatcaatatt tgcctatctg
     8641 atttatcgtg ccaaaacaaa tagctataac cgcttttacc ataaggcacg attacttccc
     8701 ttacattttg cagagtttcc cccgccaccg acaaatcata aggtttaccg ttacccgggc
     8761 tgccttgtgt agaaacaaaa gaatttttaa gcagccgcat cactgtattt gcctgatgtt
     8821 ccgcacccaa atcattcaaa aaattataaa tcctgaccaa atcagattgg gcggggcgtg
     8881 taatgaccaa cttcacttgc ggcattcggg catatccttc ggttcatcgc cacccaagcc
     8941 gtccacccag tccgcaaact cattaagcgt aatatgcaac cctgtttcct gataatcctg
     9001 aaaagcctgc atcgcccgct tatcgtaggc ttgtttggct ttcaaccgtt ctatatgacc
     9061 gtccaccgca tccaatacga tactgtgcac actgcccccg aaatcccggg ccagctcttg
     9121 taaaacggct ttgcggtatc ccagtttgac accggttact tcctgattgg taagcatcat
     9181 tattttccca taaatcaaac gtctgacacg gcattataaa cacaatgcgg catctgccgc
     9241 cacccttgcg gacgcggcgt taccggcttc ctcagctatt tcgacaagca gccgctgcaa
     9301 ggcggacaat acgactgtca ggcaggctcg ttccacgtcc gcgtggtcat cgtccgttaa
     9361 acatatcggc aatcaaaaaa tgccgtctga aacatttttc agacggcata gtttataaat
     9421 caaatcggta atacagataa tcgttcaatt aggattgctt ctgcaggtgg gacaacacat
     9481 taaggtgttg cccgatgccc tgtctgaaga aaacgccact gtttccgact gtgaaacaca
     9541 ggataaatat caacgggctt ttgcttcttt tttgcctgca aatacgccga agccgctctt
     9601 atgctcattg ttatctttat agctgtatct gcctgccatt tctgcgccat cttcaccata
     9661 aaatcttccg gaaatatcgc cttttccttc ttcgtttgcc tgccacgttc ccttaaagct
     9721 gttatttcca tcaaattgcg cggtaaagtt ttgcgtaccc atacctgaag gatctttggt
     9781 atcaattttt cctgttacgg ttttctgtga gaaatcaacc tctgccgtaa acttgcctgc
     9841 cgctttatat gcgctatgat tgaaccaatc ttccttatat ttcccggcaa aatgcaatac
     9901 attgcctgta tatttagcat tacctaccgg caatgtttct gtcggcttac cctgtacaaa
     9961 aagggtgtat gtgccgtctt ttaatttagt agccccataa atcagatgct catattgttt
    10021 ttgagaaact attaccttat taaaatcatc actcatcaaa ccgcgatgat tacttgatac
    10081 tggttcatca gctttcgtca aatcaatggt ttctccgcca atcatcaacg ccgtgatttc
    10141 tcccgtaccg tcaaaatatt tctcgccaaa cacgcctgtt ttaggttgat tattggcagc
    10201 attttggggt tgttggtctt gatcttgggg ggaatgagcg gccgggtcat cgccttgcaa
    10261 tccctcttcc gcatcctgcc tgccgtcatc tgcctgcatc ccgccttgcc ccgccccttc
    10321 ggaattttcg gcttccgacg gcgggtttgc accttcggta ttcgtcgcaa cctcagtatg
    10381 ttcggcgttt tcagaaggag ggtttgccgg catccctgtg ccttcgctta cagcgtttcc
    10441 ttccgtacca tctagagatt ccgcattttt cggcgcatcg gtatcttgat tgccgccatc
    10501 cgaccctacg gcatcactgc cgggcatacg gttgttttca ggctgcgtct caggtgtgcc
    10561 ggttgccggc gcattatcat tatgttcatg tccggtttct tcagaaggag gacttgcctg
    10621 catccccgca tcttcgctta cagcgttttc ttccgtacca tcttgagatt ccgtattttt
    10681 cggcgcatcg gtatcttgat tgccgccatc cgaccctacg gcatcactgc cgggcatact
    10741 gttgttttca ggctgcgtct cgggtgtgcc ggttgccggc gcattatcat tatgttgggg
    10801 cgcatcattt tgcactccgc catcagtgcc tgccggtgcg ctttcccctt gcgtatcttt
    10861 aggcggtatt tctgttttag aatccccgcc atccccacct gccgaggggc ttgccgtatc
    10921 agcacctgta gcagggtttc ccgtatcagt gggggggggt ggcaacttta tttgacggtg
    10981 tttccgagga tttgaccgca ggcgcatccc ctcctcctga aatacaggcg gaaagggcaa
    11041 ggacggatgc cattgcaagc aggcttggtt tgaaaggaat cgtcataatt atctcctaat
    11101 ggcatatttt taataaaaaa tatgataatt atttatattt gatggtttga aaaatgccgt
    11161 catacgcggc agaaaatacg gttccgcttc acgagacgag gcgaaaccgt aaaatatatc
    11221 aatgcctgtg cggcatcata ccctcggggg cttcggcatc ggctgccaag ccgaaggttt
    11281 cgcgcaacac gactttgtag aatgcaaagg cttcgcgcgc gccttggatg gcttccgctt
    11341 cggcttcggg agtcaggttc aaagcgttca gatgctcgac gaaggcgcgc cagtgtttgc
    11401 cgcgcccgtc gggatgcgga gcgaggtggc gcgcgccgtg ttcgccgttg taatcgagtt
    11461 tttgggcgtg tttgaacaaa aacgccgcgc ccaaattgga tccttcggcg caataaagcc
    11521 agccgattgc tttgttgcca gtttcgtatg gcaattcttt gtcgaatttg taaggctctt
    11581 cgcccaaatc tttcaagtct tgcgttacgg catcgtatcg cgccatgtat tccagctcgg
    11641 gaatggcttt gtttaattcg gcatctttat agatgtggtc gacggccttg tggaaaacgg
    11701 attggagttt caaaaatttg atgtagtttt ctttgctgac aaacggttgg acagacataa
    11761 cgaggttatc cacgctgtcg tgaatagccg tggtatccgc cttcaagcgt ttggcaaacg
    11821 tcagggcttg attttcggtt tcgctcatag gttttccttt gtcggtaagg gataaggatg
    11881 cggtgcgggc aaaatccgca cttgcccgca
//
LOCUS       DAXIDM010000057        11819 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000057 DAXIDM010000000
VERSION     DAXIDM010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 11819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11819
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.057"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..182)
                     /locus_tag="ACFOAE_001312"
     CDS             complement(<1..182)
                     /locus_tag="ACFOAE_001312"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884787.1"
                     /translation="MPSESGGFFGSDGFGPIHSHENKNLKSRHSRKSGNLVYPASAIS
                     DTFPHASIPSFLRFQS"
     gene            complement(226..1269)
                     /gene="argC"
                     /locus_tag="ACFOAE_001313"
     CDS             complement(226..1269)
                     /gene="argC"
                     /locus_tag="ACFOAE_001313"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HFC6884788.1"
                     /translation="MSKKIKVGIVGATGYTGVELLRLLAAHPDVEVAAVTSRSEAGTA
                     VADYFPSLRGVYGLAFQTPDEAGLEQCDIVFFATPNGIAMKDAPRLIEQGVRVIDLSA
                     DFRIRDIPTWEHWYGMTHAAPGLVSQAVYGLSELNREAVAQARLVANPGCYPTCVSLP
                     LVPLLRQCRLKPGMPLIADCKSGVSGAGRKGNVGSLLCEVGDNFKAYGIAGHRHLPEI
                     RQTIAGLQDGIAEGFVFTPHLVPMIRGMHATVYLHLSDGICPETVLRDYYRDSPFVDI
                     LPAGSTPETRSVRGANLCRISIQQAAQSDVWVVLSVIDNLVKGAAGQAVQNMNIMFGL
                     KETHGLDAIPLLP"
     gene            complement(1266..1559)
                     /locus_tag="ACFOAE_001314"
     CDS             complement(1266..1559)
                     /locus_tag="ACFOAE_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884789.1"
                     /translation="MKTLVLLLLSFSTTTAFAAYGLGLGQAPKYPADFRAYGYVYSGR
                     QGWVLKTEADAIKLDTLFKRFVYRPSAANQNPVGQAVGQRSDGIPANHTKEKP"
     gene            1814..2968
                     /locus_tag="ACFOAE_001315"
     CDS             1814..2968
                     /locus_tag="ACFOAE_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFC6884790.1"
                     /translation="MSIHLDFGISPKTFRQTYLYQKPKLFKGAVRNLESASWKDINEI
                     YQRADPTAPLFHLRKKGAIVPKEEYVESFDDLGKTRYRFIKSVIYEHMKNGASLVYNH
                     INNEPFSDHIARQVARFAGAHTIVSGYLAFGSDESYKNHWDTRDVYAIQLFGKKRWQL
                     TAPDFPMPLYMQQTKDTDISIPEHIDMDIILEAGDVLYIPRGWWHRPIPLGCETFHFA
                     VGTFPPNGYNYLEWLMKKFPTIESLRHSFSDWEQDRTRINDTAAQIAAMIADPVNYEA
                     FSEDFLGKERTDTAFHLEQFANPNATPLSDDVRLRLNANNLDTLEKGYLIGNGMKISV
                     DELGKKVLEHIGKNEPLLLKNLLVNFNQGKHEEVRKLIYQLIELDFLELL"
     gene            2977..3183
                     /locus_tag="ACFOAE_001316"
     CDS             2977..3183
                     /locus_tag="ACFOAE_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884791.1"
                     /translation="MKNWKQFTFFVILVIACYQLLYFLSDMFLLDYINKYSWNLNFIQ
                     GTLNFFSIYLPYVFVSRIFRNTNQ"
     gene            3388..3747
                     /locus_tag="ACFOAE_001317"
     CDS             3388..3747
                     /locus_tag="ACFOAE_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HFC6884792.1"
                     /translation="MERKNNIIELSIEDLELIYGGGLGERILEGGANGAQIGGSIGAG
                     IGLGVGIVSGGIPAGPAIILGGTVGAAVGAATGMGVAAYEYYQETQPKGTVTVGPISA
                     FAVDKSGNGYTDSTNYC"
     gene            4147..4586
                     /locus_tag="ACFOAE_001318"
                     /pseudo
     CDS             4147..4586
                     /locus_tag="ACFOAE_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4914..5216
                     /locus_tag="ACFOAE_001319"
     CDS             4914..5216
                     /locus_tag="ACFOAE_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884793.1"
                     /translation="MTWVGGSGNAQQSSYYCEICESAGLNDTGNPDKSLGLPNNTFSN
                     PPGWGATIGALAGSRIGMPEFGTFASHAIENFDWSWYRRYREIAETIEREYSGGLP"
     gene            5500..5652
                     /locus_tag="ACFOAE_001320"
                     /pseudo
     CDS             5500..5652
                     /locus_tag="ACFOAE_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009117473.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
     gene            5800..7539
                     /gene="hrpB"
                     /locus_tag="ACFOAE_001321"
     CDS             5800..7539
                     /gene="hrpB"
                     /locus_tag="ACFOAE_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion system transporter HrpB"
                     /protein_id="HFC6884794.1"
                     /translation="MKFFPAPCLLVILAVIPLKTLAADENDAELIRSMQRQQHIDAEL
                     LTDANVREQPLEKNNYVLSEDETPCTRVNYISLDDKTARKFSFLPSVLMKETAFKTGM
                     CLGSNNLSRLQKAAQQILIVRGYLTSQAIIQPQNMDSGILKLRVSAGEIGDIRYEEKR
                     DGKSAEGSISAFNNKFPLYRNKILNLRDVEQGLENLRRLSSVKTDIQIIPSEEEGKSD
                     LQIKWQQNKPIRFSIGIDDAGGKTTGKYQGNVALSFDNPLGLSDLFYVSYGRGLVHKT
                     DLTDATGTETESGSRSYSVHYSVPVKKWLFSFNHNGHRYHEATEGYSVNYDYNGKQYQ
                     SSLAAERMLWRNRLHKTSVGMKLWTRQTYKYIDDAEIEVQRRRSAGWEAELRHRAYLN
                     RWQLDGKLSYKRGTGMRQSMPAPEENGGDILPSTSRMKIITAGLDAAAPFILGKQQFF
                     YATAIQAQWNKTPLVAQDKLSIGSRYTVRGFDGEQSLFGERGFYWQNTLTWYFHPNHQ
                     FYLGADYGRVSGESAQYVSGTQLMGAVVGFRGGHKVGGMFAYDLFAGKPLHKPEGFQT
                     ANTVYGFNLNYSF"
     gene            7632..>11819
                     /gene="hrpA"
                     /locus_tag="ACFOAE_001322"
     CDS             7632..>11819
                     /gene="hrpA"
                     /locus_tag="ACFOAE_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion exoprotein HrpA"
                     /protein_id="HFC6884795.1"
                     /translation="MNKGLHRTVFSKKHNTMVAVAETANSQGKGKQAGTSAPASPQIS
                     DGLYSKLKTTLKTLVCSLVSVSMVLPAHAQIITDKTAPKNQQAVILKTNTGAPLVNIQ
                     TPNARGLSHNRYTQFDVDAKGAVLNNDRNNNPFLAKGSAQLILNEVRGAASKLNGIVT
                     VGGQKADVIIANPNGITVNGGGFKNVGRGILTTGAPQIGKDGALTGFDVRQGTLTVGA
                     AGWNDKGGADYTEILARAVALQGKLQGKNLAVSTGPQKVDYASGEISAGTAAGTKPTI
                     ALDTAALGGMYADSITLIANEKGVGVKNAGTLEAAKQLIVTSSGRIENSGRIATTADS
                     TEASPTYLSIETTETGAAGAFISNGGRIESKGLLVIDTGEDIGLRNGAVVQNNGNRPA
                     ATVLNAGRNLVIESKANVNNAKGSTNLSTGGRTVIKEASIQTGTTVYSSSKGNAELGN
                     NTRITGADVTVLSNGTISSSAVIDAKDTAHIEAGKPLSLEASTVTSDIRLNGGSIKGG
                     KQLALLADDNITAKTTNLNTPGNLYVHTGKDLNLNVDKDLSAASIHLKSDNAAHITGT
                     SKTLTASKDMGVEAGSLNVTNTNLRTNSGNLHIQAAKGNIQLRNTKLNAAKALETTAL
                     QGNIVSDGLHAVSADGHVSLLANGNADFTGHNTLTAKADVNAGSVGKGRLKADNTNIT
                     SSSGDITLVAGNGIQLGDGKQRNSINGKHISIKNNGGNADLKNLNVHAKSGALNIHSD
                     RALSIENTKLESTHNTHLNAQHERVTLNQVDAYAHRHLSITGSQIWQNDKLPSANKLV
                     ANGVLALNARYSQIADNTTLRAGAINLTAGTALVKRGNINWSTVSTKTLEDNAELKPL
                     AGRLNIEAGSGTLTIEPANRISAHTDLSIKTGGKLLLSVKGGNAGAPSAQVSSLEAKG
                     NIRLVTGETDLRGSKITAGKNLVVATTKGKLNIEAVNNSFSNYFPTQKAAELNQKSKE
                     LEQQIAQLKKSSPKSKLIPTLQEERDRLAFYIQAINKEVKGKKPKGKEYLQAKLSAQN
                     IDLISAQGIEISGSDITASKKLNLHAAGVLPKAADSEAAAILIDGITDQYEIGKPTYK
                     SHYDKAALNKPSRLTGRTGVSIHAAAALDDARIIIGASEIKAPSGSIDIKAHSDIVLE
                     AGQNDAYTFLKTKGKSGKIIRKTKFTSTRDHLIMPAPVELTANGITLQAGGNIEANTT
                     RFNAPAGKVTLVAGEELQLLAEEGIHKHELDVQKSRRFIGIKVGKSNYSKNELNETKL
                     PVRVVAQTAATRSGWDTVLEGTEFKTTLAGADIQAGVGEKARVDAKIILKGIVNRIQS
                     EEKLETNSTVWQKQAGRGSTIETLKLPSFESPTPPKLSAPGGYIVDIPKGNLKTEIEK
                     LSKQPEYAYLKQLQVAKN"
BASE COUNT         3367 a         2766 c         2832 g         2854 t
ORIGIN      
        1 aatgattgaa accggagaaa tgacggaatc gaagcgtgtg gaaatgtgtc ggaaattgct
       61 gaagccggat aaactagatt cccgcttttg cgggaatgac gggattttag gtttttgttt
      121 tcgtgggaat ggatgggccc aaagccgtcc gaaccaaaaa aaccgccgct ttcagacggc
      181 atcaaaaaac cgcaggcacg atgcctgcgg tttgccgttt gcgcttcagg ggagcagggg
      241 gattgcgtct aagccgtgtg tttccttcag tccgaacatg atgttcatat tttggactgc
      301 ctgacccgcc gcgcctttga cgaggttgtc gatgacggaa aggacgaccc acacatcgga
      361 ttgcgccgcc tgttggatgc tgatgcggca gaggtttgcg ccgcgcacgc tgcgggtttc
      421 gggtgtcgaa ccggcaggca ggatgtccac gaacgggctg tcgcggtagt agtcgcgcag
      481 gacggtttcg gggcagatgc cgtctgaaag gtggaggtaa acggtggcgt gcataccgcg
      541 tatcatcggc acgaggtgcg gcgtgaacac gaatccttcg gcgatgccgt cctgaagccc
      601 ggcgatggtc tgcctgattt cgggcaggtg gcggtgtcca gctatgccgt aggctttgaa
      661 gttgtcgccg acttcgcaca acagcgaacc gacattgcct ttcctgcccg cgccggacac
      721 gccggatttg cagtcggcaa tcagcggcat accgggcttc agacggcatt gccgcaacag
      781 cggcacgagc ggcagggata cgcaggtcgg gtagcagccg gggttggcga cgaggcgcgc
      841 ctgtgcgacg gcttcgcggt tgagttcgct caatccgtac acggcttggg aaacgaggcc
      901 gggggcggcg tgggtcatgc cgtaccagtg ttcccaggtc ggaatgtccc gtatgcggaa
      961 gtcggcggaa aggtcgatga cgcgcacgcc ctgttcaatc aggcgcggcg cgtctttcat
     1021 ggcgatgccg ttgggcgtgg cgaagaagac gatgtcgcat tgttccaaac ctgcctcgtc
     1081 gggcgtttgg aaggcgaggc cgtacacgcc gcgcaaactc ggaaagtaat cggcaactgc
     1141 agttcccgct tcgctgcggc tggttacggc ggcgacttcg acatcgggat gggcggcaag
     1201 caggcgcagc agttccacgc ccgtgtagcc cgtcgcgccg acaatgccga ctttgatttt
     1261 tttactcatg gtttttcctt tgtgtggttg gcgggtatgc cgtccgaacg ctgtccgacg
     1321 gcttgtccga cggggttttg attggcggcg gaaggacggt acacaaagcg tttgaaaagc
     1381 gtgtctaatt taatggcatc cgcctctgtt tttaaaaccc agccctgtcg tccggaataa
     1441 acataaccgt aggcgcgaaa gtcggcagga tatttcggtg cctgccccaa acccaaaccg
     1501 tatgcggcga aagcggtggt tgtggagaaa gaaagcagga ggaggacgag ggttttcata
     1561 aggttccaaa ccgaacgggg cgatgaagcc cgattatagc aaaaggtcgt ctgaaaaccg
     1621 ttttcagaag accttttatt taattacaat aaaaatgtta acaacaaaaa acaaaccgct
     1681 tttttccgtt tggagacaaa tttttaacta aaattgtcaa caattccttg acgcacacac
     1741 aaaaaaaaac tttaatattt gtaaatatat gtaacattat aaattttaaa tattttctga
     1801 gtaaggggaa gtaatgagca tccatctcga cttcggcatt agtcctaaaa cgttccgaca
     1861 gacttatctg tatcaaaagc ccaagctctt taaaggagcg gttcggaatc tcgaatccgc
     1921 atcttggaaa gatatcaacg agatatacca acgagcagac ccaaccgcac cgctgtttca
     1981 tctgcgtaaa aaaggcgcaa tcgttcctaa agaagaatac gtcgaaagtt tcgacgattt
     2041 gggcaaaact cgctaccgtt ttattaaatc cgttatctac gaacatatga agaatggtgc
     2101 gtcgttagtc tataaccata ttaacaacga gccgttttca gaccatatcg cccgtcaagt
     2161 cgcccgcttt gccggcgcac atactattgt tagtggatat cttgcttttg gcagcgacga
     2221 atcttataaa aaccattggg acacccgcga tgtgtatgcc atccagcttt tcggcaagaa
     2281 acgttggcaa cttactgccc ctgatttccc tatgccattg tatatgcaac agactaaaga
     2341 tactgatatt tccattcctg aacatatcga tatggatatt atccttgaag caggtgatgt
     2401 cctctacatc ccacgcggtt ggtggcacag acctatcccg ctcggctgtg aaaccttcca
     2461 cttcgctgtc ggtaccttcc cgcccaacgg ctataattac ctcgagtggc taatgaagaa
     2521 attccccacg atagaaagtc tgcgccacag tttctcagac tgggagcaag ataggacgcg
     2581 tatcaacgat actgccgcac aaattgctgc catgattgcc gaccccgtca attacgaagc
     2641 cttcagtgaa gacttcctcg gcaaagaacg caccgatacc gcttttcatc tcgaacagtt
     2701 cgcgaatccc aacgctactc cgctttcaga cgacgtcagg ttgagactaa atgccaataa
     2761 tttggatacg ttggaaaagg gatatttgat tgggaatggg atgaagataa gcgtagatga
     2821 attggggaaa aaagtgttag aacacatcgg taagaatgaa ccgttattgt tgaaaaatct
     2881 actggttaac ttcaatcagg gaaaacatga agaagttagg aagttgattt atcagttgat
     2941 agagttagat tttctggaac ttttgtgagg gattctatga aaaactggaa gcaatttaca
     3001 tttttcgtaa tattagtaat agcttgttat caattgctat attttttatc agatatgttt
     3061 cttctcgact acattaacaa atatagttgg aatttgaatt ttattcaggg tactttgaat
     3121 tttttttcaa tatatctgcc atatgttttt gttagccgaa tttttaggaa taccaaccaa
     3181 tgaaagacta ggctatgaaa tcaaaatttg tgtataagtt actggtgctt gcaaagtacc
     3241 tgtatatttt aatttgtata tcaataccaa tcgtttttat ttatgaaagc taccaaggag
     3301 atgatgttga ttttatgatt tatattcgtg cttttattat tttttccata ttgggtgtat
     3361 tagctcaata ttctatgtct aatttttttg gaaaggaaaa ataacatcat tgaactatcc
     3421 attgaggatc tggagctaat ttatggcgga ggcttagggg agagaatcct tgaaggagga
     3481 gcaaatggtg cacaaatagg aggatcaatt ggtgcaggta ttggtctggg tgtcggtata
     3541 gtttctggtg gtattcctgc cggaccggct attattctcg gtggcacagt tggtgctgct
     3601 gttggtgctg caactggtat gggtgttgca gcatatgagt attaccaaga aactcagccc
     3661 aaagggacag taacggtcgg tccgatttct gcttttgctg tggacaaatc aggaaacggc
     3721 tacactgaca gcacaaatta ctgctgatat ttctcatcgt ccagacaatc tctaggggtc
     3781 gtctgaaact ttcttaactt caattttatg aatagaccca agcaaccctt cttccgtccc
     3841 gaagtcgccg ttgcccgcca aaccagcctg acgggtaaag tgattctgac acgaccgttg
     3901 tcattttccc tatggacgac atttgcatcg atatctgcgt tactgattat cctgtttttg
     3961 atatttggta actatacgcg aaagacaaca gcggagggac aaattttacc tgcatcaggc
     4021 gtaatcaggg tgtatgcacc ggatacgggg acaattacag cgaaattcgt ggaagatgga
     4081 gaaaaggtta aggctggcga caagctattt gcgctttcga ccttacgttt cggcgcagga
     4141 ggtagcgtgc agcagcagtt gaaaacggag gcagttttga agaaaacgtt ggcagaacag
     4201 gaactgggtc gtctgaagct gatacacggg aatgaaacgc gcagccttaa agcaactgtc
     4261 gaacgtttgg aaaaccagaa actccatatt tcgcaacaga tagacggtca gaaaaggcgc
     4321 attagacttg cggaagatca gtagcaaaaa cggcactggg cagacaggaa ttgtcgggat
     4381 tgggcatggt atcctccgat ttggcgaaga gcaacgaacc tgtttatctt gtgaaaataa
     4441 aacccgacaa accaaccatc actgcatacg gtgaggaaaa accgctgcaa atcggcatga
     4501 cgttggaagc agacatcctg cacgagaaac ggcgattgta tgaatgggta ttggagccga
     4561 tttatagtat atcgggcaaa ctgtaagact tgaggctgaa agataaagaa gttgtctgaa
     4621 accttttcag acgaccagaa gacaatatat aaaaacacaa acttcaaaac tgcctgaaac
     4681 catccccttt tacaggcact ccgtctacag gcactccgtc tgtaaaagca aggatagggc
     4741 atctgccctt ttgattgttt gattaacgat acaaggagtt tcaaaatgag agttttatag
     4801 tggattaaca aaaaccagta cagcgttgcc tcgccttgcc gtaccatttg tactgtctgc
     4861 ggcttcgtcg ccttgtcctg atttaaattt aatccactat atgtgttcat gaaatgactt
     4921 gggtcggagg ctcaggtaat gcgcaacaaa gctcatatta ttgcgaaatt tgcgaatctg
     4981 cagggcttaa cgatacggga aatcctgata aatctttagg attgccaaac aatacgttca
     5041 gtaatccgcc tggttgggga gctacaatcg gagctttagc aggtagccgc atagggatgc
     5101 ctgaatttgg tacgtttgcg agccatgcca ttgaaaattt cgactggtca tggtatcgac
     5161 gttataggga aattgccgaa acgattgaac gagaatattc aggcggtttg ccttaatagt
     5221 tgaggaggtc atgatgtttg ccaaacatta tcaattcatc gcactcggca tcatgctgct
     5281 tctttatatg ttgattctct atacgaccga tttttccaat ctgacgtatt ggatgctgtt
     5341 ttttatctgt tttattacag gaaaaatatt agctcgtttg ttagagaaaa gctttaaata
     5401 aaatagcagc tagtcgcaaa aggtcgtctg aaaccttttc aggcggcctt tctaaaatac
     5461 atccaacttc ctaatcccta tttttcaaaa aggaaatcta tgccccatct gcaaaacctg
     5521 tctttgggct taaagaaaaa gctgcctgtt atcctgcaaa cagaaatatc agaatgcggc
     5581 ttggcatgtc tggcggctgt ggcgggattt catggtttcc atacggattt acgcgcactg
     5641 cgttcaaaat actgtccgag acctttgcaa aattccccaa aatcccctaa atgtcttggt
     5701 gggaattttg gggaattttg caaaggtctc attctataac tgtaaatact tttaaattta
     5761 tgacaaaata gtaaatattg ctaaaataat attgatgtca tgaaattttt tcctgctcca
     5821 tgtctgttgg ttatcctggc tgtcataccc cttaaaacct tagctgccga tgaaaacgat
     5881 gcagaactta tccgttccat gcagcgtcag cagcacatag atgctgaatt gttaactgat
     5941 gcaaatgtcc gcgagcaacc attggagaag aacaattatg tcctgagtga agatgaaaca
     6001 ccgtgtactc gggtaaatta cattagttta gatgataaga cggcgcgcaa attttctttt
     6061 cttccttctg tgctcatgaa agaaacagct tttaaaactg ggatgtgttt aggttccaat
     6121 aatttgagca ggctacaaaa agccgcgcaa cagatactga ttgtgcgtgg ctacctcact
     6181 tcccaagcta ttatccaacc acagaatatg gattcgggaa ttctgaaatt acgggtatca
     6241 gcaggcgaaa taggggatat ccgctatgaa gaaaaacggg atgggaagtc tgccgagggc
     6301 agtattagtg cattcaataa caaatttccc ttatatagga acaaaattct caatcttcgc
     6361 gatgtagagc agggcttgga aaacctgcgt cgtttgtcga gtgttaaaac agatattcag
     6421 attataccgt ccgaagaaga aggcaaaagc gatttacaga tcaaatggca gcagaataaa
     6481 cccatacggt tcagtatcgg tatagatgat gcgggcggca aaacgaccgg caaatatcaa
     6541 ggaaatgtcg ctttatcgtt cgataaccct ttgggcttaa gcgatttgtt ttatgtttca
     6601 tatggacgcg gtttggtgca caaaacggac ttgactgatg ccaccggtac ggaaactgaa
     6661 agcggatcca gaagttacag cgtgcattat tcggtgcccg taaaaaaatg gctgttttct
     6721 tttaatcaca atggacatcg ttaccacgaa gcaaccgaag gctattccgt caattacgat
     6781 tacaacggca aacaatatca gagcagcttg gccgccgagc gcatgctttg gcgtaacaga
     6841 cttcataaaa cttcagtcgg aatgaaatta tggacacgcc aaacctataa atacatcgac
     6901 gatgccgaaa tcgaagtgca acgccgccgc tctgcaggct gggaagccga attgcgccac
     6961 cgtgcttacc tcaaccgttg gcagcttgac ggcaagttat cttacaaacg gggtaccggt
     7021 atgcgccaaa gtatgcctgc accggaagaa aacggcggcg atattcttcc aagtacatct
     7081 cgtatgaaaa tcattactgc cggtttggac gcagccgccc catttatttt aggcaaacag
     7141 cagtttttct acgcaaccgc cattcaagct caatggaaca aaacgccgtt ggttgcccaa
     7201 gataaattgt caatcggcag ccgctacacc gttcgcggat ttgatgggga gcagagtctt
     7261 ttcggagagc gaggtttcta ctggcagaat actttaactt ggtattttca tccgaaccat
     7321 cagttctatc tcggtgcgga ctatggccgc gtatctggcg aaagtgcaca atatgtatcg
     7381 ggcacgcagc tgatgggtgc agtggtcggc ttcagaggag ggcataaagt aggcggtatg
     7441 tttgcttatg acttatttgc cggcaagccg ctgcacaagc ccgaaggttt tcagacggcc
     7501 aacaccgttt acggcttcaa tttgaattac agtttctaac cctctcctgc attttttacc
     7561 gacattcaga cagtctttca tcatttacag gccgtctgaa gcgattacaa acatcattta
     7621 aagggataaa tatgaacaaa ggtctgcatc gtaccgtttt cagcaaaaag cacaacacta
     7681 tggttgcagt tgccgaaacc gccaacagtc agggaaaagg caaacaggca ggaacttccg
     7741 ctccggcttc gccacaaatt tcagacggcc tttacagtaa actcaaaacc acgcttaaaa
     7801 ccttggtctg ctctttggtt tccgtcagta tggtattgcc tgcccacgca caaatcatta
     7861 ccgataaaac cgcgcccaaa aaccagcagg ccgttattct taaaaccaat accggtgcgc
     7921 cgttggtcaa catccaaact cctaatgccc gtggattgag ccacaaccgc tatacccagt
     7981 ttgatgtcga cgctaaaggt gctgtactga acaacgatcg caacaacaac ccgtttctgg
     8041 ccaaaggcag tgcgcagttg attttgaacg aggtgcgcgg tgcggccagc aaactcaatg
     8101 gcatcgttac cgtaggtggt caaaaggccg atgtgattat tgccaacccc aacggcatta
     8161 ccgttaatgg cggcggcttt aaaaatgtcg gtcggggcat cttaactacc ggtgcgcccc
     8221 aaatcggcaa agacggtgca ctgacaggat ttgatgtgcg tcaaggcaca ttgaccgtag
     8281 gagcagcagg ttggaatgat aaaggcggag ccgactacac cgagatactt gctcgtgcag
     8341 ttgctttgca ggggaaatta cagggtaaaa acctggcggt ttctaccggt cctcagaaag
     8401 tagattacgc cagcggcgaa atcagtgcag gtacggcagc gggtacgaaa ccgactattg
     8461 cccttgatac tgccgcactg ggcggtatgt acgccgacag cattaccctg attgccaatg
     8521 aaaaaggcgt gggtgtcaaa aatgcgggca cactcgaagc ggccaagcaa ttgatcgtta
     8581 cttcctccgg ccgtattgaa aacagcggcc gcatcgccac cactgccgac agcactgaag
     8641 catcaccgac ttatctctcc atcgaaacca ccgaaacagg cgcagcaggc gcatttatct
     8701 ccaatggcgg ccggatagag agcaaaggct tattggttat tgataccggg gaggacatcg
     8761 gtttgcgtaa cggagcggtc gttcaaaaca acggcaaccg ccctgctgct acggtattaa
     8821 atgccggccg taatttggtt atcgaaagca aagcaaatgt gaacaatgct aaaggttcga
     8881 ccaatctgtc gaccggcggc cgtaccgtca tcaaggaggc cagtattcag actggcacta
     8941 ccgtatacag ttccagcaaa ggcaacgccg aattaggcaa taacacacgc attaccgggg
     9001 cagatgttac cgtattatcc aacggcacca tcagcagttc cgccgtaata gatgccaaag
     9061 acaccgcaca catcgaagca ggcaaaccgc tttctttgga agcttcaaca gttacctccg
     9121 atatccgctt aaacggaggc agtatcaagg gcggcaagca gcttgcttta ctggcagacg
     9181 ataacattac tgccaaaact accaatctga atactcccgg caatctgtat gttcatacag
     9241 gtaaagatct gaatttgaat gttgataaag atttgtctgc cgccagcatc catttgaaat
     9301 cggataacgc tgcccatatt accggcacca gtaaaaccct cactgcctca aaagacatgg
     9361 gtgtggaggc aggctcgctg aatgttacca ataccaatct gcgtaccaac tcgggtaatc
     9421 tgcacattca ggcagccaaa ggcaatattc agcttcgcaa taccaagctg aacgcagcca
     9481 aggctctcga aaccaccgca ttgcagggca atatcgtttc agacggcctt catgctgttt
     9541 ctgcagacgg tcatgtatcc ttattggcca acggtaatgc cgactttacc ggtcacaata
     9601 ccctgacagc caaggccgat gtcaatgcag gatcggttgg taaaggccgt ctgaaagcag
     9661 acaataccaa tatcacttca tcttcaggag atattacgtt ggttgccggc aacggtattc
     9721 agcttggtga cggaaaacaa cgcaattcaa tcaacggaaa acacatcagc atcaaaaaca
     9781 acggtggtaa tgccgactta aaaaacctta acgtccatgc caaaagcggg gcattgaaca
     9841 ttcattccga ccgggcattg agcatagaaa ataccaagct ggagtctacc cataatacgc
     9901 atcttaatgc acaacacgag cgggtaacgc tcaaccaagt agatgcctac gcacaccgtc
     9961 atctaagcat taccggcagc cagatttggc aaaacgacaa actgccttct gccaacaagc
    10021 tggtggctaa cggtgtattg gcactcaatg cgcgctattc ccaaattgcc gacaacacca
    10081 cgctgagagc gggtgcaatc aaccttactg ccggtaccgc cctagtcaag cgcggcaaca
    10141 tcaattggag taccgtttcg accaaaactt tggaagataa tgccgaatta aaaccattgg
    10201 ccggacggct gaatattgaa gcaggtagcg gcacattaac catcgaacct gccaaccgca
    10261 tcagtgcgca taccgacctg agcatcaaaa caggcggaaa attgctgttg tctgtaaaag
    10321 gaggaaatgc aggtgcgcct agtgctcaag tttcctcatt ggaagcaaaa ggcaatatcc
    10381 gtctggttac aggagaaaca gatttaagag gttctaaaat tacagccggt aaaaacttgg
    10441 ttgtcgccac caccaaaggc aagttgaata tcgaagccgt aaacaactca ttcagcaatt
    10501 attttcctac acaaaaagcg gctgaactca accaaaaatc caaagaattg gaacagcaga
    10561 ttgcgcagtt gaaaaaaagc tcgcctaaaa gcaagctgat tccaaccctg caagaagaac
    10621 gcgaccgtct cgctttctat attcaagcca tcaacaagga agttaaaggt aaaaaaccca
    10681 aaggcaaaga atacctgcaa gccaagcttt ctgcacaaaa tattgacttg atttccgcac
    10741 aaggcatcga aatcagcggt tccgatatta ccgcttccaa aaaactgaac cttcacgccg
    10801 caggcgtatt gccaaaggca gcagattcag aggcggctgc tattctgatt gacggcataa
    10861 ccgaccaata tgaaattggc aagcccacct acaagagtca ctacgacaaa gctgctctga
    10921 acaagccttc acgtttgacc ggacgtacgg gggtaagtat tcatgcagct gcggcactcg
    10981 atgatgcacg tattattatc ggtgcatccg aaatcaaagc tccctcaggc agcatagaca
    11041 tcaaagccca tagtgatatt gtactggagg ctggacaaaa cgatgcctat accttcttaa
    11101 aaaccaaagg taaaagcggc aaaatcatca gaaaaaccaa gtttaccagc acccgcgacc
    11161 acctgattat gccagccccc gtcgagctga ccgccaacgg tatcacgctt caggcaggcg
    11221 gcaacatcga agctaatacc acccgcttca atgcccctgc aggtaaagtt accctggttg
    11281 cgggtgaaga gctgcaactg ctggcagaag aaggcatcca caagcacgag ttggatgtcc
    11341 aaaaaagccg ccgctttatc ggcatcaagg taggtaagag caattacagt aaaaacgaac
    11401 tgaacgaaac caaattgcct gtccgcgtcg tcgcccaaac tgcagccacc cgttcaggct
    11461 gggataccgt gctcgaaggt accgaattca aaaccacgct ggccggtgcc gacattcagg
    11521 caggtgtagg cgaaaaagcc cgtgtcgatg cgaaaattat cctcaaaggc attgtgaacc
    11581 gtatccagtc ggaagaaaaa ttagaaacca actcaaccgt atggcagaaa caggccggac
    11641 gcggcagcac tatcgaaacg ctaaaactgc ccagcttcga aagccctact ccgcccaaat
    11701 tgtccgcacc cggcggctat atcgtcgaca ttccgaaagg caatctgaaa accgaaatcg
    11761 aaaagctgtc caaacagccc gagtatgcct atctgaaaca gctccaagta gcgaaaaac
//
LOCUS       DAXIDM010000058        11531 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000058 DAXIDM010000000
VERSION     DAXIDM010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 11531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11531
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.058"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(1..1183)
                     /locus_tag="ACFOAE_001323"
                     /pseudo
     CDS             complement(1..1183)
                     /locus_tag="ACFOAE_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003678130.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            1329..2033
                     /locus_tag="ACFOAE_001324"
     CDS             1329..2033
                     /locus_tag="ACFOAE_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248833.1"
                     /note="The SIMPL domain is named for its presence in mouse
                     protein SIMPL (signalling molecule that associates with
                     mouse pelle-like kinase). Bacterial member BP26, from
                     Brucella, was shown to assemble into a channel-like
                     structure, while YggE from E. coli has been associated
                     with resistance to oxidative stress; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIMPL domain-containing protein"
                     /protein_id="HFC6884796.1"
                     /translation="MLRSILAASLLAVSFPAAAEALNYNIVEFSESAGVEVAQDTMSA
                     RFQVAAEGRDKNAVNAEFVKKFNSFNRKSKNGSFKTELVSRSAMPRYQYTNGRRIQTG
                     WEERAEFKVEGRDFDALNRFIADVQADAALEYTDFHVSRERRNEVIDQVSKDAVLRFK
                     ARAEKLAGVLGASGYKIVKLNLGHIGSHIAGGGAAQAKMLRAMPMAASYGVEGTDSVA
                     PGVEEISISVNGTVQF"
     gene            complement(2098..2664)
                     /gene="dcd"
                     /locus_tag="ACFOAE_001325"
     CDS             complement(2098..2664)
                     /gene="dcd"
                     /locus_tag="ACFOAE_001325"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003823864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008829 - dCTP deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006229 - dUTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HFC6884797.1"
                     /translation="MSIKSDKWIRRMSEEFGMIDPFEPNQIKEADGKRIISYGTSSYG
                     YDIRCANEFKIFTNINSTIVDPKNFDPKNFVTVEDDCCIIPPNSFALARTVEYFRIPR
                     NVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGVAQVLFF
                     ESDEVCETSYKDRNGKYMGQTGVTLPKA"
     gene            complement(2730..3145)
                     /locus_tag="ACFOAE_001326"
                     /pseudo
     CDS             complement(2730..3145)
                     /locus_tag="ACFOAE_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3207..4106)
                     /locus_tag="ACFOAE_001327"
     CDS             complement(3207..4106)
                     /locus_tag="ACFOAE_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HFC6884798.1"
                     /translation="MWFKQISFYPLNKEKLPEADVLADKLAEAEFTHCQGLDWFSEGF
                     TAPVSFSQELVFPADFTLRVALKKEEKVLPAGVIRDILEEKVAEIQNNEARNVGRKEK
                     QELKEQITDDLLPRAFTRSSRTEAVFNTRHGYLLVNNAASAKVENILTKLREALGGLE
                     ASLPNTKQSPSSLMTGWLLQGHCEGGFELDRDCELKGTGDIVPVVKVSKQDLTADEVV
                     QHVKNGKTVTQLGLVWREQIAFILTQDFTLKRIQYLDVLQEEAESNGDDAAGLAFASQ
                     ILMAESVSTMLEELVSYLGGWQD"
     gene            complement(4137..5594)
                     /gene="der"
                     /locus_tag="ACFOAE_001328"
     CDS             complement(4137..5594)
                     /gene="der"
                     /locus_tag="ACFOAE_001328"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003745900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFC6884799.1"
                     /translation="MKPTIALVGRPNVGKSTLFNRLTRTKDALVHDLPGLTRDRHYGH
                     GKVGSKPYLVIDTGGFEPVVDSGILHEMAKQTLQAVDEADAVVFLVDGRTGLTPQDKI
                     IADRLRQSPRPVYLAVNKGEGGNRAVLAAEFYELALGDPYVISGAHGDGVYYLIEDIL
                     ETFPEPEAEEADAKHPVFAVIGRPNVGKSTLVNAILGEERVIAFDMAGTTRDSIHIDF
                     EREGKPFTIIDTAGVRRRGKVDEAVEKFSVIKAMQAVEAANVAVLVLDAQQDIADQDA
                     TIAGFALEAGRALVVAVNKWDGISEERREQVKRDINRKLYFLDFAKFHFISALKERGI
                     DGLFDSIQAAYNAAMIKMPTPKITRVLQSAIERQQPPRAGLVRPKMRYAHQGGMNPPV
                     IVVHGNSLHAISDSYTRYLTQTFRKAFNLQGTPLRIQYNVSENPYENAEDKPKKKPLR
                     RVSLSNRIEKREGRKEEKNRFKKKTKVSVKKQFSK"
     gene            complement(5744..6373)
                     /locus_tag="ACFOAE_001329"
     CDS             complement(5744..6373)
                     /locus_tag="ACFOAE_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgM family protein"
                     /protein_id="HFC6884800.1"
                     /translation="MAAHLEEQQELDNFKYFWKTTGKWLFAVLILAALGYLGYTVYQN
                     RAASQNQEAAAVLANIVEKAQNKAPQSEINAELTKLQQSYPHSISAAQATLMAAATEF
                     DAQRYDVAEGHLKWVLSNQKDSLIQALAAQRLGVVLLQQKKYDAALAALDTPVEADFA
                     PLLMETKGDVYAAQGKSQEALKNYGQALEKMPQDSVGRELVQMKLDSLK"
     gene            complement(6374..7669)
                     /gene="hisS"
                     /locus_tag="ACFOAE_001330"
     CDS             complement(6374..7669)
                     /gene="hisS"
                     /locus_tag="ACFOAE_001330"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFC6884801.1"
                     /translation="MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVNRWTRAYG
                     YRQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVE
                     HNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLW
                     EKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDT
                     KNPDLQEICNAAPRLVDYLGEASQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTV
                     FEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERLLLLVSEYGSLEVNA
                     APDVYAMHQGERADLQVMKYAQALRAQGFNVMQHSGYQSLKAQMKKADNSGARFALIV
                     AQDELANGTVTLKDMNGAHGQQTVAAEDLTHTLQQWKNA"
     gene            complement(7796..8377)
                     /locus_tag="ACFOAE_001331"
     CDS             complement(7796..8377)
                     /locus_tag="ACFOAE_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFC6884802.1"
                     /translation="MFNDNPVVYGKIKVQSWKERRDFNIVKQDLDFSCGAASVATLLN
                     NFYGQTLTEEEVLKKLDKEQMRASFEDMRRIMPDLGFEAKGYALSFEQLAQLKIPVIV
                     YLKYRKDDHFSVLRGIDGNTVLLADPSLGHVSMSRAQFLDAWQTREGNLAGKILAVVP
                     KKAETISNKLFFTHHPKRQTEFAVGQIRQARAE"
     gene            complement(8510..8701)
                     /locus_tag="ACFOAE_001332"
     CDS             complement(8510..8701)
                     /locus_tag="ACFOAE_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884803.1"
                     /translation="MLPTRSVSSLLLGEYLEFEENDTKITAEIGSAWHFLGAACRISI
                     NGKYYAGNRIVWFAKKAES"
     gene            complement(8822..9271)
                     /locus_tag="ACFOAE_001333"
     CDS             complement(8822..9271)
                     /locus_tag="ACFOAE_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884804.1"
                     /translation="MEKIIDSKVRETNFNQAWRVIRAMQIDNISDEQVVIVRMSCYLK
                     KDEIFKNIERYGYQSSDIKKISPPFPLNILPVPKPYYFYLYDTHLNQIYDLAWSCNDF
                     LMFEIFILDRESIKYIDKDKLFKSGETLYSNFKSIKNQCKNYFFLRF"
     gene            complement(9439..9597)
                     /locus_tag="ACFOAE_001334"
     CDS             complement(9439..9597)
                     /locus_tag="ACFOAE_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884805.1"
                     /translation="MKTFEKTWSAQYRDMEISVRIFWNLERTGAEVYINGRRVYHNEA
                     EMASASLR"
     gene            complement(9754..10173)
                     /locus_tag="ACFOAE_001335"
     CDS             complement(9754..10173)
                     /locus_tag="ACFOAE_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884806.1"
                     /translation="MSFGYLIATSQPCELLTKSRGETFSLIMDKMDLWIYFRFCEGNI
                     YTIRKNETESCLTERGGKWLKHIYEFNRGSFIFSYVLLKKRESEENFAEIVLKSIKNN
                     KILTVKVRSGLHFDLRNIYRIEMYSGLNLNQYGVASP"
     gene            complement(10231..10596)
                     /locus_tag="ACFOAE_001336"
     CDS             complement(10231..10596)
                     /locus_tag="ACFOAE_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884807.1"
                     /translation="MEKPLLTPPFFLFEDVSLDIFQGLSELEKKIEPQDLMDDVYRAF
                     DSVGNILNFRIVEKEQKGFWVSTKIKTVVFDSADMSSDDLFLKCLQSSYKAYFETEPA
                     GLDKRQLMKTLIQKCGFSC"
     gene            complement(10578..11126)
                     /locus_tag="ACFOAE_001337"
     CDS             complement(10578..11126)
                     /locus_tag="ACFOAE_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884808.1"
                     /translation="MKKQITAAMMILTMIAAPAMANSMDNQIFENQVFHTRADAPMQL
                     AELSQKEMKETEGAFLPLAILGGAAIGMWTQHGFSYATTGRPASVRDVAIAGGLGAIP
                     GGVGAAGKVVSFAKYGREIKIGNNMRIAPFGNRTGHPIGKFPHYHRRVTDNTGKTLPG
                     QGIGRHRPWESKSTDRSWKNRF"
     gene            complement(11214..11438)
                     /locus_tag="ACFOAE_001338"
     CDS             complement(11214..11438)
                     /locus_tag="ACFOAE_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884809.1"
                     /translation="MMKNKYILTKAAIGITAISIFYLLNQESSGKTEEPSYFLMFMFL
                     NLLWFEENKTVMAAVTAIIAAHFIFVALSD"
BASE COUNT         2851 a         2718 c         2754 g         3208 t
ORIGIN      
        1 ggtattttct taccgtattc tgcgattgcc tgtcggaaaa tgccgatcaa cctgcctata
       61 acggcatttt cgccaaattc gttcagacag ttttccctaa gtcgggcagg ttcaaaatca
      121 gagtggtgtt catacatttt gatgagtgcg tcggcaaggg catcgtcgtc gtcaacagga
      181 accaaatatc cgttgccgtc tgaaacaata gattccgcac cgccgcagcg tgtcgcaatg
      241 acgggcaatc cttgggacag tgcttcgata tagaccacgc cgaaggtttc ggtgcggctg
      301 gcaaggacga atgcgtcgct gttcctcatc aaatccaaga ctgcttcggg ctgcaatgcg
      361 cccaaaaatg taacggcatg ggtaatgccc aagtctgccg cctgctgttt cagccgctgt
      421 tcttcctgtc cgctgccgcc gatgttcagg cgcagttgcg ggcattgtgc caacgcccgg
      481 gcaaaggcag tgagtaggac atcgtgtcct ttgagacggc gaaggtgcga gacggtgcag
      541 aacacgaaat gcggtttgtt gtttttttct ctttgttcaa acggtcggtt gaatattccg
      601 cccagtatgt tgggggaggt actgccattc gcagccgtat ttgtgttgca ggacgtgtgc
      661 gaaatggcgg ctgacagcga gcagtgcgga ggcgtgcgcc gctgcttttt ccatcggctg
      721 ccattggtgg ggacggatca gaccgcgcgt gatggtgctg ctgtgttccg tgacgacata
      781 ggggatgccg tatttttggg aaattttttg ggcgagtatg ccggcatagt tcatgcggtg
      841 ggcgtgaatc aggtcgggca gcccgttttc gcggatgtag tgtttgaaag ctttcaaacc
      901 cgcacacacc cagcggatgc agtcgatgtc gatgaacgga aagcggggga agaaatatat
      961 gccgtgccat gcatagatgt ccaaaccgct ttgccgatat tttgcaaaac cgtaaggccg
     1021 gtcaggatgc ttgctgtttc tttccgcaag tagcggaaca tcggtgcaag cacggcggtt
     1081 ttgatgcctt tcctctgcaa tgccagtgcc tgattttgaa aaaaatcccg tccacatcct
     1141 gttcggattg cggataccat gaggggatga cgaggacgtg caagggttcg ggcatagtgg
     1201 gattccgtat cggaaaggcg gttattataa gacagacgca gaccgaatat ttaaattgtt
     1261 gccttacgct aatgcaattt agcgcgccga tatgctagat tggcggtttt atgagtgagg
     1321 atacggatat gttgcgttct attttggcgg cttccctatt ggcggtatct tttccggcag
     1381 cggctgaagc attgaattac aatattgtcg aattttccga atcggcgggt gtcgaggtgg
     1441 ctcaggatac aatgtccgca cgtttccaag tggcggcgga aggacgggac aaaaatgccg
     1501 tcaatgccga gtttgttaaa aaattcaaca gttttaacag aaaatcgaaa aacggcagct
     1561 ttaaaaccga attggtatcg cgcagtgcga tgccgcgcta ccagtacacc aacggcagac
     1621 gcattcaaac aggctgggag gagcgtgcgg aatttaaggt cgagggtagg gattttgatg
     1681 cgttgaaccg ttttattgcc gatgttcagg cagatgccgc gttggaatat acggatttcc
     1741 atgtgtcgcg cgaacgccgc aacgaggtca tcgatcaggt cagcaaggat gccgttttgc
     1801 gtttcaaggc gcgtgccgaa aagttggcgg gcgttttggg tgcgtccggt tataaaatcg
     1861 tcaaattgaa tttgggacac atcggcagcc atatcgcggg tgggggagct gctcaggcaa
     1921 aaatgcttcg tgccatgccg atggcggcaa gttacggcgt ggagggtacg gattccgttg
     1981 cacctggtgt ggaggaaatc agcatcagcg tcaatgggac ggttcagttc tgatttgagg
     2041 tgaacggtaa atgccgtctg aaacccgacg ataagggttc agacggcatt ttgtgtttca
     2101 ggctttgggc agggttacgc cggtttgtcc catgtatttg ccgttgcggt ctttgtatga
     2161 agtttcgcac acttcgtcgc tctcgaaaaa caggacttgc gccacgcctt cgccggcgta
     2221 gattttggcg ggcagggggg tggtgttgga aaattcgagg gtaacgtagc cttcccattc
     2281 cggttcgaac ggggtaacgt tgacgatgat gccgcagcgt gcgtaggtcg atttgcccaa
     2341 gcagacggtc aggacgttgc gcgggatgcg gaaatattcg accgtgcgcg ccagtgcgaa
     2401 ggaattgggc gggatgatgc agcagtcgtc ttcaacggta acgaagtttt ttgggtcgaa
     2461 gtttttggga tcgacgatgg tgctgttgat gttggtgaag attttaaatt cgtttgcgca
     2521 gcggatgtcg tagccgtagc tggacgtacc gtaggagatg atgcgtttgc cgtcggcttc
     2581 tttgatttgg ttcggctcga aggggtcgat catgccgaat tcttcgctca tgcggcgtat
     2641 ccatttgtcg gacttgatgc tcataatgtt ttccttgttt cttgcagtgt tcggacaaag
     2701 cattggggga tgccgtctga aaacggggct tatttgtttt taggcagttt cacttcttta
     2761 atcatgccgt tttcgcattt cataatgaag agggtttcgc cgttttgcga gacggtaaat
     2821 ctgccgtgtg ccaagccttt tttgaacgtg cccgagagta ccatgttgcg gaatttggta
     2881 ctgtcggaat tgaacggttc gataaatatt tcgcggttgg cggcaacggt ataaacgcct
     2941 tgtccgtcga atttgccatt tttaaacgaa ccggtatagt tgcgcccgtc ttggcagcgc
     3001 atgtgccttt gcctgaagga agcccgtctt ttccgactcc gccttcgtag gtgcagccgg
     3061 gttcttgata ggaagtcaga acggcggccg aagtggggag ggcgaacatc atggcgggca
     3121 gtaggaatgc gagatgttta agcataaggg ttattccatt ggattttggt tgacggtatt
     3181 ttgtcgtgaa aaagccgtct gaaaaatcaa tcttgccagc cgcccaaata ggaaaccagc
     3241 tcttccaaca tggtgctgac ggattccgcc atcagaattt gcgaggcgaa ggcaaggccg
     3301 gcggcatcgt cgccgttgct ttcggcttct tcctgcaata cgtcgaggta ttggatgcgc
     3361 ttgagtgtga agtcttgagt gaggataaag gcaatttgtt cgcgccacac caagcccagt
     3421 tgggttacgg ttttaccgtt tttgacgtgt tgaaccactt cgtcggcggt taaatcttgt
     3481 ttggatactt tgacgacggg aacaatatcg cccgtacctt tgagttcgca atctctgtct
     3541 aattcaaaac cgccttcgca atgcccttgc aacagccagc cggtcatcag ggaagagggc
     3601 gattgtttgg tattcggcag cgaggcttcc aaaccgccca aagcttcgcg cagcttggtc
     3661 aggatgtttt ccactttggc ggaagctgcg ttattgacga gcaggtagcc gtggcgggtg
     3721 ttaaacaccg cttctgtacg gctgctgcgg gtaaatgcgc ggggcagcag gtcgtctgta
     3781 atttgctctt taagctcttg tttttctttg cgaccgacat tgcgggcttc attgttttgg
     3841 atttccgcta ccttctcttc caaaatatcg cggatgacgc cggcaggcag gactttttcc
     3901 tcttttttca gggcgacgcg caaggtaaag tcggcaggga aaacgagttc ctgggagaat
     3961 gaaaccggtg cggtaaagcc ttcgctgaac cagtctaagc cttggcaatg ggtaaattca
     4021 gcttcagcaa gtttgtcggc aagtacgtcc gcctcaggca gcttttcttt gttgagcgga
     4081 taaaaactaa tctgcttgaa ccacataatg tttcctgttg tttgaaatgt cgggaattat
     4141 ttgctgaatt gttttttcac actgactttg gttttcttct tgaagcggtt tttctcttcc
     4201 tttcggcctt cgcgtttctc aatacggttg ctcaggctga cgcggcgcag cggttttttc
     4261 ttcggtttgt cttccgcatt ttcatacggg ttttccgaaa cattgtattg aattctgagc
     4321 ggcgtgcctt gcagattgaa ggctttgcgg aacgtttggg tcagatagcg cgtatagctg
     4381 tcggaaatcg cgtgcagcga attgccgtgt accacaatta cgggagggtt catgccgcct
     4441 tggtgggcat aacgcatttt cggacgcacc aagccggcac gcggcggttg ctgacgctcg
     4501 atcgcgcttt gtaatacgcg cgtgattttc ggcgtcggca tcttaatcat cgccgcgttg
     4561 taggcagcct gaatgctgtc aaacaaaccg tctataccgc gctctttcaa tgcggaaata
     4621 aagtggaact tggcaaaatc gaggaaatac agtttgcggt tgatatcgcg tttcacttgc
     4681 tcgcgacgct cttcgctgat gccgtcccat ttgttgacgg caaccaccaa ggcgcggcct
     4741 gcttccaaag caaaaccggc aatcgtcgca tcttggtcgg cgatgtcctg ctgcgcgtcc
     4801 aataccaaaa cagcgacgtt tgccgcttca accgcctgca tcgctttgat aacggagaat
     4861 ttttctactg cttcatccac tttgccgcga cggcgcacgc ctgcggtatc gatgatggta
     4921 aacggtttgc cttcgcgttc gaaatcgatg tggatgctgt cgcgtgtcgt gcctgccata
     4981 tcgaaagcaa tcacgcgctc ttcgccgagg atggcgttaa ccagtgtgga tttgccgacg
     5041 ttcggacggc cgatgacggc aaagacggga tgttttgcat cggcttcttc ggcttccggc
     5101 tctgggaaag tttccaaaat atcttcaatc agataataca cgccatcgcc gtgcgcacct
     5161 gaaataacat aagggtcgcc caaagcaagt tcgtagaact cggcggcaag cacggccctg
     5221 ttgcccccct cgcctttatt cacggccaaa taaacagggc gcggactttg gcgcaaacgg
     5281 tcggcaataa tcttgtcttg cggtgttaaa ccggtacggc cgtccaccaa aaacacaact
     5341 gcatcagctt catcgacagc ctgtaaggtt tgttttgcca tttcgtgcaa aatgccgctg
     5401 tccacaaccg gctcgaaacc gccggtatcg atgaccaaat aaggtttgct gccgactttg
     5461 ccgtgtccgt aatggcggtc gcgcgtcaga ccgggcaggt catgcacgag cgcgtctttg
     5521 gtgcgcgtca aacggttgaa taaagtagat ttgccgacgt tggggcgacc aacaagcgcg
     5581 atggttggtt tcatgattga gtctttctgt gtcaagtgcc gttcgggaga actgaacacg
     5641 agcaggtgtc cgttggacac ggcggatggg ttttacggga attgccgtag gatagtgttg
     5701 tctgaaatgc cgtctgaaga gagggtggca tttcagacgg catttatttc agcgaatcaa
     5761 gtttcatttg aaccaattcg cgaccgacag aatcttgagg cattttttct aaagcctgtc
     5821 cgtagttttt taaggcttcc tggctttttc cctgtgcggc atagacatcg cctttggttt
     5881 ccatcagcag gggggcgaag tccgcttcaa ccggcgtgtc gagcgcggca agtgcggcat
     5941 cgtatttttt ttgttgcaac aacacaacgc ccagacgctg cgccgccaac gcttgaatca
     6001 ggctgtcttt ttggttggac aacacccatt tcaaatggcc ttcagcaaca tcgtaacgct
     6061 gcgcgtcaaa ttcggttgcc gccgccatca gcgtggcttg ggcggcggaa atggaatgcg
     6121 ggtagctttg ttggagtttg gtcaattcgg cattgatttc gctttgcggg gctttgtttt
     6181 gcgccttttc cacgatgttt gccagcaccg ccgccgcttc ctgattttgg gaagccgcac
     6241 ggttttggta aaccgtgtat cccaagtagc cgagcgccgc caaaatcagc acggcaaaca
     6301 gccatttgcc cgtggttttc caaaaatatt taaagttgtc taactcttgt tgttcttcga
     6361 gatgggctgc catttatgcg ttcttccatt gttgtaaagt atgggttaaa tcctcggcgg
     6421 cgacagtttg ctgaccgtgt gcgccgttca tgtctttgag cgtaaccgta ccgttcgcca
     6481 gttcgtcttg cgcgacaatc agggcaaagc gcgcgccgct gttgtcggct tttttcattt
     6541 gcgctttcag gctttgatag ccggaatgct gcattacatt gaaaccttgc gcgcgcaagg
     6601 cttgtgcgta tttcatcacc tgcaagtccg ccctttcgcc ttggtgcatt gcatagacat
     6661 caggcgcagc gttcacttcc agcgagccgt attcgctcac caaaagcagc agccgctcga
     6721 tacccattgc aaagccgatg gacggcgcag gcttaccgcc aagttcctca atcaaaccat
     6781 cgtaacggcc gccgccgcac acagtcgcct gcgcgccgag tttgtcggtt gtccactcaa
     6841 aaaccgtctg attgtaataa tccaaaccgc gaaccaagcg cggattttca atatattgga
     6901 tacccaaacc gtccaacatc gccttgaagc gtgcatagtg gttttgcgaa gcctcgccca
     6961 aataatccac caaacgcggc gccgcgttgc agatttcctg caaatcaggg tttttcgtat
     7021 ccaaaacgcg caaaggattg gttttcagac ggcgtttgct gtcttcatcc aatttatctt
     7081 cataacgggt cagatattca accaatgccg cacggtgtgc cgcgcgttcc tcacggttgc
     7141 ccaaactgtt gatttccaaa gtcagatatt cgcggatacc caatttttcc cataagtcgg
     7201 cagacatcgc gatgatttcc gcatcaatat ccggaccttc aaaacccaaa gcttcgatac
     7261 cgacctgatg gaactgacga taacggcctt tttgcggacg ctcgcggcgg aacatcggtc
     7321 ccatatacca cagcttttgc gggctgttgt agagaagatt gtgttcgacc accgcacgca
     7381 gacaggaagc cgtaccttca ggacgcaggc tcaaactcaa agaatcgttt gaatcggaaa
     7441 aggtgtacat ttccttgccg accacgtcgg tttcctcgcc gatggagcgg acaaacaaac
     7501 cggtttgctc gacaatcggc gtacggattt gccgataacc gtaagcgcgc gtccaacggt
     7561 ttaccgtatc ctcaaacgcc tgccaaaacg cagccgtcag tttgaaatct ttttgctcga
     7621 caggcagaag gtcgttcata cctttgacgg attggatttt ttgtgccatt tcaagtaaaa
     7681 atgcttaaat caaattgcgg gcgattatag cggattttta agggcttgtg aggatggaga
     7741 tggtttgcag acgggtaaaa atgccgtctg aaacagtttt cagacggcat ttgacttact
     7801 ctgcacgtgc ttgcctgatt tgtccgactg caaactctgt ctgccgcttg ggatgatgtg
     7861 tgaaaaacaa tttatttgaa attgtctcgg cttttttcgg cacgaccgcc aaaatcttac
     7921 ctgccaaatt tccctcacgg gtttgccaag catccaaaaa ctgcgccctg ctcattgaaa
     7981 catgacccag cgacgggtcg gcaagcaaaa ccgtattgcc gtctatcccg cgcaataccg
     8041 aaaaatggtc gtctttgcgg tatttcagat acacgatgac ggggattttc aactgtgcga
     8101 gctgctcgaa agacagggca tagcctttcg cttcaaaacc caaatctggc ataatgcgcc
     8161 gcatatcctc aaacgacgcg cgcatctgct ccttatccag ctttttcaac acttcttctt
     8221 ccgtcagcgt ttgcccgtaa aaattgttca aaagcgtcgc caccgaagcc gccccacagg
     8281 aaaaatccaa atcctgcttt acaatattga aatcccgcct ttctttccaa ctctgcactt
     8341 tgatttttcc gtaaacaaca ggattatcgt taaacatcgg tgcagcattc aaacgataag
     8401 ataaagaaac gacaacacac gccaacagaa aaacatattt gaacttcatc atattgtcca
     8461 cataaagggc agcctgaaaa tctttcaggc tgcccttgtc aaattattcc tagctttcgg
     8521 cttttttggc aaaccaaaca atccgattac ccgcataata ctttccattt attgaaatcc
     8581 gacaagccgc gcccaaaaaa tgccatgcac tgccgatttc cgcagtaatc tttgtatcgt
     8641 tttcttcaaa ttccaaatat tcacccaata ataaacttga aacagaacgc gtgggcagca
     8701 agtgcccacc ctacgcctat tcaaataatt tgattaaata aagaataaag aaaatgcatc
     8761 aggaacaaaa ttataatctg ccacctgact cacaccgctt ttaaagtaag gggcatcaaa
     8821 atcaaaaccg caaaaaaaaa taatttttgc attgattttt aatagattta aaatttgaat
     8881 atagtgtttc tccagattta aaaagtttat ctttatctat atatttgatg ctttccctat
     8941 ccaaaataaa tatttcaaac attaaaaaat cattacatga ccaagccaaa tcataaattt
     9001 gattcaaatg ggtatcataa agataaaaat aataaggttt gggaacaggt aaaatattta
     9061 atggaaaagg aggactaatt ttcttaatat ctgatgactg atatccatat ctttctatat
     9121 tcttaaaaat ttcatctttc ttaagataac aagacattct gacaatcaca acctgttcat
     9181 cggatatatt atctatttgc atggcgcgta taacacgcca tgcctgatta aaattagtct
     9241 cccttacctt agaatctatt atcttttcca aagatgaaaa tgccccttat cttgaactct
     9301 ccagttagaa cctggaagtt tcgtacctct taaatgtgta ttaatatttc ttatagtttc
     9361 attaaaatgc cacgcgctgc cgatttcaac ggtaattttc gtaccgcttt cttcaaattc
     9421 caggtattcc cccattagct aacgcaaaga agcagacgcc atttcggctt cgttatgata
     9481 aacccgcctt ccgttgatat agacttccgc ccctgtccgc tccaaattcc aaaaaatccg
     9541 tactgaaatt tccatatccc gatattgtgc agaccatgtt ttttcgaagg ttttcataaa
     9601 atttcctata cctgtccaat cggcacatat caattgcatt attatagtgg attaacaaaa
     9661 atcaggacaa ggcaacgaag ccgcagacag tacaaatagt acgaaaccga ttcacttggt
     9721 gcttcagcac cttagagaat cgttctcttt gagctaaggc gaggcaacgc cgtactggtt
     9781 taaatttaat ccgctataca tctcaatacg ataaatattt cttaagtcaa aatgcaagcc
     9841 tgaccgtacc ttaactgtca aaattttatt attttttatt gattttaaaa caatttctgc
     9901 aaaattctct tcgctttctc tcttttttag aagcacataa gaaaaaataa aacttccccg
     9961 attaaattca taaatatgtt tcaaccattt gcctcctctt tctgtaagac aagattcagt
    10021 ttcattcttc cttattgtat aaatatttcc ttcacaaaat ctgaaataaa tccataaatc
    10081 catcttatcc ataattaaag aaaaagtttc acctcgagat tttgtcaaca attcgcaagg
    10141 ttgcgatgtt gcaatcaaat agccgaaaga cattttttac ctcatacatg gtcgaaatca
    10201 gtttctgtta gttcagaatc cattttttcg tcaacaactg aatccgcatt tttgaattaa
    10261 cgttttcatc agctgccgtt tatctaaacc ggcaggttca gtttcaaaat aagccttata
    10321 tgaagactgt aagcatttca gaaaaagatc atcagaagac atatctgccg aatcaaatac
    10381 aactgttttg attttggtac ttacccaaaa ccctttttgc tctttttcta ctatacggaa
    10441 attcagaata tttccaaccg aatcaaaagc acggtaaaca tcatccatca aatcctgcgg
    10501 ctctattttc ttttccaatt ccgacaatcc ttgaaatata tccaaagaca catcttcaaa
    10561 tagaaaaaaa ggaggagtta gaagcggttt ttccatgatc tgtccgtaga ttttgattcc
    10621 caagggcgat gacgaccaat tccctgtcca ggcaaagtct tgcccgtatt atccgtaact
    10681 cgacgatgat aatggggaaa ttttccaata ggatgacctg ttctattacc gaaaggggct
    10741 atccgcatat tattgccgat tttaatctca cgtccatatt tagcaaagga aacaaccttt
    10801 cctgcggcgc ctacaccacc aggaattgcg cctaatccgc cagcaatagc aacatctcta
    10861 acagaagctg gtctgcctgt cgttgcataa ctaaaaccat gctgtgtcca cataccaatg
    10921 gcagcaccac ccaagatagc caatggaaga aacgccccct cagtctcctt catctccttc
    10981 tgagaaagct ccgccaactg catcggcgca tctgcccgcg tatggaatac ttggttttca
    11041 aatatctgat tgtccatgct gtttgccatc gccggagcgg caatcattgt cagaatcatc
    11101 atcgctgcgg taatttgttt tttcataaca aattcttagg gaggagataa tgttccatca
    11161 aaatcctcct gaaaggctgc ctgaaatttc caagcagcct ttttgtttgc ttattagtcg
    11221 gatagtgcga caaatataaa gtgggcggca attattgccg taacggcagc cataactgtt
    11281 ttattttctt caaaccaaag caagttgaga aacataaaca tcaagaaata tgatggttct
    11341 tcagttttgc cgctgctttc ttgatttaga agataaaata tagatatggc ggttatgccg
    11401 attgctgctt ttgttaaaat atatttgttt ttcatcatct tgtatggttt ttcatgcaag
    11461 tttcaacaat aaaattcgga ataagataga gagatgttga tatatcagat aaatatatag
    11521 tggattaaat t
//
LOCUS       DAXIDM010000059        11255 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000059 DAXIDM010000000
VERSION     DAXIDM010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.059"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..1048)
                     /locus_tag="ACFOAE_001339"
     CDS             complement(<1..1048)
                     /locus_tag="ACFOAE_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HFC6884810.1"
                     /translation="MQNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAA
                     YNAGAEVVKHQTHIVEDEMSDEAKQVIPGNADVSIYEIMERCALNEEDEIKLKEYVES
                     KGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPIILSTGMNSI
                     ESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDLSEAFPDAIIGLSDHTLD
                     NYACLGAVALGGSILERHFTDRMDRPGPDIVCSMNPDTFKELKQGAHALKLARGGKKD
                     TIIAGEKPTKDFAFASVVADKDIKKGELLSGDNLWVKRPGNGDFSVNEYETLFGKVAA
                     CNIRKGAQIKKTDIS"
     gene            complement(1049..1735)
                     /gene="neuA"
                     /locus_tag="ACFOAE_001340"
     CDS             complement(1049..1735)
                     /gene="neuA"
                     /locus_tag="ACFOAE_001340"
                     /EC_number="2.7.7.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acylneuraminate cytidylyltransferase"
                     /protein_id="HFC6884811.1"
                     /translation="MEKQNIAVILARQNSKGLPLKNLRKMNGISLLGHTINAAISSKC
                     FDRIIVSTDGGLIAEEAKNFGVEVVLRPAELASDTASSISGVIHALETIGSNSGTVTL
                     LQPTSPLRTGAHIREAFSLFDEKIKGSVVSACPMEHHPLKTLLQINNGEYAPMRHLSD
                     LEQPRQQLPQAFRPNGAIYINDTASLIANNCFFIAPTKLYIMSHQDSIDIDTELDLQQ
                     AENILNHKES"
     gene            complement(1739..2872)
                     /gene="neuC"
                     /locus_tag="ACFOAE_001341"
     CDS             complement(1739..2872)
                     /gene="neuC"
                     /locus_tag="ACFOAE_001341"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFC6884812.1"
                     /translation="MKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKT
                     YGRTYKEVTRENYQHTYLFSNQIQGEPMGAVLGNTITFISRLSDEIEPDMVMIHGDRL
                     EALAGATIGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMG
                     EKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYA
                     AQYFKALELSGQNIISIYPNNDTGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHA
                     KFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSIIHTDYETKNIFDAIQQACSLG
                     KFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL"
     gene            2999..4174
                     /gene="ctrA"
                     /locus_tag="ACFOAE_001342"
     CDS             2999..4174
                     /gene="ctrA"
                     /locus_tag="ACFOAE_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export outer membrane
                     protein CtrA"
                     /protein_id="HFC6884813.1"
                     /translation="MFKVKFYIRHAVLLLCGSLIVGCSAIPSSGPSAKKIVSLGQQSE
                     VQIPEVELIDVNHTVAQLLYKAQINQSFTQFGDGYASAGTLNIGDVLDIMIWEAPPAV
                     LFGGGLSSMGSGSAHQTKLPEQLVTARGTVSVPFVGDISVVGKTPGQVQEIIKGRLKK
                     MANQPQVMVRLVQNNAANVSVIRAGNSVRMPLTAAGERVLDAVAAVGGSTANVQDTNV
                     QLTRGNVVRTVALEDLVANPRQNILLRRGDVVTMITNPYTFTSMGAVGRTQEIGFSAR
                     GLSLSEAIGRMGGLQDRRSDARGVFVFRYTPLVELPAERQDKWIAQGYGSEAEIPTVY
                     RVNMADAHSLFSMQRFPVKNKDVLYVSNAPLAEVQKFLSFVFSPVTSGANSINNLTN"
     gene            4189..5352
                     /gene="ctrB"
                     /locus_tag="ACFOAE_001343"
     CDS             4189..5352
                     /gene="ctrB"
                     /locus_tag="ACFOAE_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide export protein CtrB"
                     /protein_id="HFC6884814.1"
                     /translation="MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVIS
                     LVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAILQGTGFARAQDDIYTVGEYMRSR
                     SSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGIST
                     LNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQN
                     LTDYRIANGVFDLKAQSEVQMGLVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQARE
                     QSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLAAAMTSLESAKVEAD
                     RQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN"
     gene            5352..6149
                     /locus_tag="ACFOAE_001344"
     CDS             5352..6149
                     /locus_tag="ACFOAE_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004519071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC6884815.1"
                     /translation="MKALHKTSFWESLAIQRRVIGALLMREIITRYGRNNIGFLWLFV
                     EPLLMTFVIVLMWKFLRADRYSTLNIVAFAITGYPMLMMWRNASKRAVGSISSNASLL
                     YHRNVRVLDTILARMILEIAGATIAQIVIMAVLIAIGWIEMPADMFYMLMAWLLMAFF
                     AIGLGLVICSIAFNFEPFGKIWGTLTFVMMPLSGAFFFVHNLPPKVQEYALMIPMVHG
                     TEMFRAGYFGSDVITYENPWYIVLCNLVLLLFGLAMVSKFSKGVEPQ"
     gene            6146..6796
                     /locus_tag="ACFOAE_001345"
     CDS             6146..6796
                     /locus_tag="ACFOAE_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC6884816.1"
                     /translation="MISVEHVSKQYQMRGGMRTVLDDINFSLQKGEKVGILGRNGAGK
                     STLIRLISGVEPPTTGEIKRTMSISWPLAFSGAFQGSLTGMDNLRFICRIYNVDIDYV
                     KNFTEEFSELGQYLYEPVKRYSSGMKARLAFALSLAVEFDCYLIDEVIAVGDSRFADK
                     CKYELFEKRKDRSIILVSHSHSAMKQYCDNAMVLEKGHMYQFEDMDKAYEYYNSLP"
     gene            6861..9134
                     /locus_tag="ACFOAE_001346"
     CDS             6861..9134
                     /locus_tag="ACFOAE_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFC6884817.1"
                     /translation="MNITQILSQELSATTAQINAAIELLDDGATVPFIARYRKEATGG
                     LDDTQLRRLAERLQYLRELEERKAVVLKSIEEQGKLSDGLRAQIEAADNKTALEDLYL
                     PYKPKRRTKAQIAREHGLQPLADVLLAEQSQDVEAAAQGYLNENVPDAKAALDGARAI
                     LMEQFAEDAELIGTLRDKLWNEAEIHAQVVGGKETESEKFSDYFDHREPIRAMPSHRA
                     LAVLRGRNEGVLNIALKYQPDDTPITQQSEYEQIIARRFKVSDGHKWLRDTVRLTWRA
                     KIFLSLELEALNRLKEAADTDAITVFARNLKDLLLAAPAGRLTTLGLDPGYRNGVKCA
                     VVDDTGKLLDTVIVYLHQENNMLATLSRLIKQHGVKLIAIGNGTASRETDKIAGELVR
                     GMPEMGLHKIVVSEAGASIYSASELAAREFPDLDVSLRGAVSIARRLQDPLAELVKID
                     PKSIGVGQYQHDVNQSQLAKSLDAVVEDCVNAVGVDVNTASAPLLARISGLNQTLAQN
                     IVAYRNENGAFDSRKKLLKVPRLGEKTFEQAAGFLRINGGTEPLDASAVHPEAYPVVA
                     KMLAQQGISAAELIGNRERVKQIKASDFTDERFGLPTILDILSELEKPGRDPRGEFQT
                     ASFAEGIHEISDLQVGMILEGVVSNVANFGAFVDIGVHQDGLVHISALSNKFVQDPRE
                     VVKAGDVVKVKVLEVDAARKRIALTMRLDDEPGGAKHKMPSENRSRERTAGRKPQRND
                     RAPANSAMADAFAKLKR"
     gene            9165..10163
                     /locus_tag="ACFOAE_001347"
     CDS             9165..10163
                     /locus_tag="ACFOAE_001347"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFC6884818.1"
                     /translation="MHTPLTYIDLFSGAGGLSLGFEQAGFQQLLSVEMESDYCQTYRT
                     NFPHHQLLQKDLTTLTEQDLINCLNGQAVDLIIGGPPCQGFSMAGKIGRTFTDDPRNH
                     LFKEFVRIVKIVQPYFFVMENVARLYTHNSGKTRIEIIQAFQNIGYSVECKILSAADF
                     GVPQIRSRVIFIGRRDKGKISFPEPLQISHQTVGSAIGHFPKLAAGESNPHVANHEAM
                     NHSAQMLEKMAFVKNGGNRNDIPEPLRPKTGDIRKYIRYNSNKPAVCITGDMRKVFHY
                     EQNRALTVRELAALQSFPDNFIFCGSKIAQQQVGNAVPPLLAKAIAESILKMSENE"
     gene            10156..11199
                     /gene="galE"
                     /locus_tag="ACFOAE_001348"
     CDS             10156..11199
                     /gene="galE"
                     /locus_tag="ACFOAE_001348"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFC6884819.1"
                     /translation="MNKQYPKINYIGNKEKIASWICDQLPSDVDTVADVFSGGCSFAY
                     EAKKRGYRVITNDILAINYQIALALIENNHETLNDDDGAMIFSGSPHAGFMSQRYAEK
                     FYFHDEYQQLDLYRKNIGKLDNQYKRALAFTLMRRAMIRKMPYTEDMRPGDTANPYGA
                     SKAMVERMLTDIQKADPRWSVILLRYFNPIGAHESGLIGEQPNGIPNNLLPYICQVAA
                     GKLPQLAVFGDDYPTPDGTGMRDYIHVMDLAEGHIAAMKAKGGLSGVHLFNLGSGRAY
                     SVLEIIRAFEAASGLNIPYQIQPRRAGDLACSFADPSHTKQETGWETKRGLKQMMEDS
                     WRWVSRNPDGYGD"
BASE COUNT         2954 a         2411 c         2788 g         3102 t
ORIGIN      
        1 aactaatatc agtttttttg atttgagcac ctttgcgaat attgcaagca gcgaccttac
       61 caaataatgt ttcatattcg ttgacgctga agtctccatt gcctgggcgt ttaacccata
      121 ggttatctcc ggacaacagt tctccttttt taatgtcttt atctgctacg acagatgcaa
      181 aggcgaaatc tttagttggc ttttctcccg cgataatcgt gtcttttttg ccgccgcgtg
      241 ccaattttaa agcatgagcg ccttgcttga gctctttaaa agtatccgga ttcatagagc
      301 atacaatatc cggacctggg cgatccatgc ggtcagtaaa gtgacgctct aaaatcgaac
      361 cgcctaaagc tactgctcct aagcaagcat agttatctaa ggtatggtca gacaggccaa
      421 tgattgcgtc tggaaaggct tcagataaat cgttcatacc acccaatcga acatcttcgt
      481 aaggggttgg gtagatgttg gtacagtgaa gcaaagcata aggtacccct gcttctcgaa
      541 taatttctac cgactttttg atgctttcaa tagaattcat gccggtagag agaataatag
      601 gcttaccaaa agaggccacc agtttaatta atgggtagtt attacattcg ccagagccga
      661 ttttatatgc tggaatatcc atacgttgta atcgtaaagc agctgcacga gagaaaggag
      721 tactgataaa aatcataccc ttactctcta cgtattcttt taatttaatc tcatcttctt
      781 cattcagggc gcaacgttcc ataatttcat aaatagagac atctgcattg cctggaatga
      841 cttgtttggc ctcatcagac atttcgtctt caacgatgtg tgtttgatgt ttaacaactt
      901 cagcgcctgc attataggca gcatcaacca tttcaaaagc tgtttttaaa gagccttcat
      961 gattgatgcc gatttcacag ataatcaatg gttcgtggtt gtaacctact gaacgattac
     1021 caattttaaa ttcgttgttg ttttgcattt agctttcctt gtgattaaga atgttttctg
     1081 cctgttgtaa atcaagctca gtatcaatat cgatagagtc ttgatgagac ataatataaa
     1141 gtttggttgg ggcgataaaa aaacaattat ttgcaattag tgaagcagta tcattaatgt
     1201 aaattgcacc attaggccta aatgcctgag gtaattgttg gcgaggctgc tccaaatcgc
     1261 ttagatggcg catgggggca tattcgccat tattgatttg aagcagggtt tttagtggat
     1321 gatgctccat tgggcatgca gagacaacgg atccttttat tttctcatca aatagagaaa
     1381 aagcttcacg aatatgagcc cctgtgcgta atggactggt tggttgtaat agggttactg
     1441 tgccggaatt actgccaatt gtttctaaag catgtattac acctgaaata gagctggctg
     1501 tatcggaggc cagctctgca gggcgtagga cgacttcgac accgaaattt ttagcttctt
     1561 ctgcaattaa cccgccatca gtcgaaacaa ttatgcggtc aaaacacttt gatgatatag
     1621 cagcattaat tgtatgacca agtaatgata tgccattcat tttccggaga ttttttaatg
     1681 gcaatccttt ggagttttgg cgcgcaagta taaccgcaat attttgtttt tccataattt
     1741 aaagattcaa atcgataaaa cgtttttgag cagaaacatt ccacgtttca ggattgttga
     1801 ttacttcagc aaatctttct gtgctggtgc gagtatctcc gccattaaag gtatcatctg
     1861 cttcaaattt gcctaaactg catgcttgtt gaatcgcatc aaagatattt ttagtttcat
     1921 aatctgtatg aataatagat tttcccatat ggcggttact ttggcgtgta ccaacatcaa
     1981 ttgaagggac accgtagaga ggagcttctc taatacctgc acttgagttg ccgaccataa
     2041 atttagcatg tttcaataag actaaaaaat attcaaatcg aatggaagga aatgcaataa
     2101 atttatcaga ttgatatttt aataattctt gcagaatact ttcagtgcca gtgtcattat
     2161 tagggtagat gctaatgata ttttggccac ttaattctaa tgctttgaaa tattgggccg
     2221 catattgtgg cattaaatgt gcttctgtag tcacggggtg aaacatagaa ataccataat
     2281 tttcgtatgg taaaccgtaa tattctttga cttcttctaa ggatgggagg gtggaagagg
     2341 ccataacatc taaatcgggg gagccgatga tgtgaatatg ctttcttttt tctcccattt
     2401 gcactaggcg agtgacagct tgttcatttg ctaccaagtg gatatgagaa agtttactaa
     2461 tagaatgacg aatggagtca tctactgtac cagatagttc accaccttcg atatggcaaa
     2521 ctaaacggct gcttaatgca cctatagttg cgcctgctag tgcttctaaa cggtcgccgt
     2581 gaatcatgac catatcaggt tcaatttcat cagatagacg agagataaac gtaatggtat
     2641 tgcctaaaac ggcacccatt ggttcacctt ggatttgatt tgaaaacaga tatgtatgtt
     2701 gatagttttc tcgagttact tccttgtagg ttctgccata tgttttcatc atatgcatac
     2761 cagttacaat caaatgcaat tcaaggtctg ggtgattttc aatataggct aataaaggtt
     2821 ttagcttgcc gaagtcggct ctggtacctg taatgcaaag aattcttttc atgattttag
     2881 aatctatagg cataaggaag ttggaaagaa gaatactaat tatactctac gtactcataa
     2941 atttatttcg attaagtgct ataattaggc catttataat tatattagga tttggcttgt
     3001 gtttaaagtg aaattttata ttcgtcacgc agtattatta ttgtgtggaa gtttaattgt
     3061 aggatgctct gcgattcctt catcaggccc cagcgcaaaa aaaattgtct ctttagggca
     3121 acaatctgaa gttcaaattc ctgaagtgga gctgattgat gtgaatcata cggttgctca
     3181 gttattatat aaggctcaga taaatcagtc attcactcag tttggcgatg gttatgcttc
     3241 ggctggtacg ctaaatattg gtgatgtatt ggatattatg atttgggaag cgccgccggc
     3301 agtattgttt ggtggtggcc tttcttcgat gggctcgggt agtgcgcatc aaactaagtt
     3361 gccagagcag ttggtcacgg cacgtggtac ggtttctgtg ccgtttgttg gcgatatttc
     3421 ggtggtcggt aaaacgcctg gtcaggttca ggaaattatt aaaggccgcc tgaaaaaaat
     3481 ggccaatcag ccacaagtga tggtgcgttt ggtgcagaat aatgcggcga atgtgtcggt
     3541 gattcgtgct gggaatagtg tgcgtatgcc gctgacggca gccggtgagc gtgtgttgga
     3601 tgcggtggct gcggtaggtg gttcaacggc aaatgtgcag gatacgaatg tgcagctgac
     3661 acgtggcaat gtagtacgaa ctgttgcctt ggaagattta gttgcaaatc cgcgacaaaa
     3721 tattttgctg cgtcgcggtg atgtggttac catgattacc aatccctata cctttacgtc
     3781 tatgggtgcg gtggggagaa cacaagaaat cggtttttca gccagaggct tatcgctttc
     3841 tgaagccatt ggccgtatgg gcggtttgca agatcgccgt tctgatgcgc gtggtgtgtt
     3901 tgtgttccgc tatacgccat tggtggaatt gccggcagaa cgtcaggata aatggattgc
     3961 tcaaggttat ggcagtgagg cagagattcc aacggtatat cgtgtgaata tggctgatgc
     4021 gcattcgcta ttttctatgc agcgctttcc tgtgaagaat aaagatgtat tgtatgtgtc
     4081 gaatgcgccg ttggctgaag tgcagaaatt cttgtcgttt gtgttctcgc cggttaccag
     4141 tggcgcgaac agtattaata atttaactaa ttaatgtgag taattaagat gtctgagcaa
     4201 cttcctgtgg cagttgccac tgaaaccaaa gccgagcgta aaaagccgaa aaagaaaagt
     4261 tggattaaaa agctaagccc tttattttgg gtaacggtga ttatccctac ggtaatttcg
     4321 ttggtgtatt tcggcttctt cgcttccgat cgttttacgt cgcaatcgag ctttgtggtg
     4381 cgctcgccta aaagccaatc ttctctcaat ggcctgggtg ccattttgca gggcacaggt
     4441 tttgcccgtg cgcaagatga tatttacacg gttggggagt atatgcgttc gcgctcgtct
     4501 ttggatgaac tgcgtaaaat cttgccggtg cgtgagtttt atgaaaccaa aggtgatgcg
     4561 ttcagccgct ttaatgggtt tgggttccgt ggcgaggaag aggcttttta tcaatactat
     4621 aaaaatcagg tgatgatcaa ttttgatacg gtttcgggta tttccacgtt gaatgtaact
     4681 tcctttgatg cgctggaatc taagaaaatc aatgaggctt tgttaaaaca aggtgaagca
     4741 ttgattaacc agttgaacga tcgtgcacgt gctgatacgg tgcgctatgc ggaagaagta
     4801 gtgaaaacgg cggcagagcg ggtaaaggaa gcctctcaga atctgacgga ttaccggatt
     4861 gccaatggcg tttttgattt gaaagcgcaa tcggaagtgc aaatggggtt ggtttccaag
     4921 ctgcaagatg aattgattgt gattcaaacc cagctggatc aggtgaaagc agtcactccg
     4981 gagaatccgc agattccggg tttgcaggcg cgtgagcaga gcttgcgtaa agaaattgac
     5041 caacagttac gtgccatttc gggcggtggg cattcttcgt tgtctaatca ggctgccgaa
     5101 tatcagcgtg tgtatttgga aaaccagttg gcagagcagc agttggcagc cgccatgact
     5161 tctttggaaa gtgccaaggt tgaagcagac cgtcagcagc tttatttgga agtgatctcg
     5221 caaccgagcc tgccggattt ggcacatgag cctaaacggt tatacaacat tgttgccact
     5281 ctgattatcg gcttgatggt ttatggtatt ttgagcctgt tgactgccag cattcgtgag
     5341 cataaaaact gatgaaagcc ttgcataaaa catcattttg ggaatcttta gccattcaaa
     5401 ggcgcgtaat cggtgcgctg ttgatgcggg aaattatcac ccgttacggt cgcaataata
     5461 ttggcttttt atggctgttt gttgagccgt tgctgatgac attcgttatc gtcttgatgt
     5521 ggaaattttt aagggcagac cgatattcaa ctttgaatat tgtcgcattt gcgattactg
     5581 gctatccgat gttgatgatg tggcgtaatg cctcaaaacg ggcagttggg tcgatttctt
     5641 caaatgccag cttgctttat caccgcaatg taagagtttt ggataccatc ttggcgcgca
     5701 tgattttgga aattgctggt gcaaccattg cgcagattgt gattatggcg gtattgattg
     5761 cgattggctg gattgaaatg ccggcagata tgttttatat gctgatggct tggcttttga
     5821 tggctttttt tgcgattggt ttgggtttgg tgatttgttc gattgccttt aatttcgagc
     5881 cgtttggcaa gatttggggc acattgactt ttgtgatgat gccgttatcc ggtgcgttct
     5941 tttttgtgca taatttgccg cccaaggtac aagaatatgc attaatgatt ccgatggtgc
     6001 atggcacaga aatgttccgt gccggatatt ttggcagcga tgtaattacc tatgaaaatc
     6061 cttggtatat cgtattgtgc aatctggtgt tgttgttgtt tggcttggcg atggtcagta
     6121 aattcagtaa aggagtcgag ccgcaatgat ttcggttgaa catgtttcca agcagtatca
     6181 aatgcgcggc ggtatgcgga cggtgttaga cgatatcaat ttttcgctgc aaaagggtga
     6241 gaaagttggt attttgggtc gaaacggtgc aggtaaatcg acgttgatcc gtttgattag
     6301 tggtgtcgag ccgccgacca cgggtgaaat caagcggaca atgagtattt cttggccttt
     6361 ggcattctcc ggtgcgtttc aaggtagtct gaccggtatg gacaatttgc gtttcatctg
     6421 ccggatttac aatgtcgata tcgattatgt gaagaacttt accgaagagt tttccgagtt
     6481 ggggcaatat ctttacgagc cggtcaagcg ttattcttca ggtatgaagg cgcgtttggc
     6541 atttgctttg tcgttggcgg tagagtttga ttgctatttg attgacgaag tgattgcagt
     6601 tggtgactcg cgctttgccg ataaatgtaa gtacgagttg tttgaaaagc gcaaagaccg
     6661 ttccatcatc ttggtgtcgc acagccacag cgccatgaag caatattgcg ataatgcgat
     6721 ggtgctggaa aaagggcata tgtaccagtt tgaagatatg gacaaagcct acgaatatta
     6781 taattcgctg ccttaaagcg attgtttttt aaatcaggcc gtctgaaatt tcagacggcc
     6841 tgtccgttgg aattctattg atgaacatta ctcaaattct ttcccaagaa ctttccgcga
     6901 ctaccgcgca aatcaatgcc gctattgagc ttttagacga cggcgcaacc gtgccgttta
     6961 tcgcgcgtta ccgtaaagaa gccaccggcg ggctggacga cacgcagctg cgccggcttg
     7021 ccgagcggct gcaatacctg cgcgagttgg aagagcgcaa agccgttgtg ttaaaaagca
     7081 ttgaagagca aggcaaactt tcagacggcc tccgcgcgca aatcgaagcc gccgacaaca
     7141 aaaccgcgct ggaagacctg tatctgccct acaagcccaa acgccgcacc aaggcgcaaa
     7201 ttgcgcgcga acacggtttg cagccgctgg cagacgtgtt gcttgccgag cagtcgcagg
     7261 acgtggaagc cgccgcacaa ggctacctga acgaaaacgt ccccgatgcc aaagccgcgt
     7321 tggacggcgc gcgtgcgatt ctgatggagc agtttgccga agacgcggaa ctcatcggca
     7381 cgctgcgcga caagctgtgg aacgaagccg aaatccacgc gcaagttgtt ggaggcaaag
     7441 aaaccgaaag cgaaaaattc agcgattatt ttgaccaccg cgaacctatt cgtgcgatgc
     7501 ccagccatcg tgcgctagcg gttttgcgcg gacgcaacga aggcgtgttg aacatcgcgc
     7561 tcaaatatca gcccgacgac acgccgatta cgcagcaaag cgaatacgag caaatcatcg
     7621 cccgccgctt caaagtttca gacggccaca aatggctgcg cgacaccgtg cgcctgactt
     7681 ggcgcgcgaa aatctttttg tcgttggaac ttgaagctct caatcgtttg aaagaagccg
     7741 ccgacaccga cgcgattacc gtgttcgccc gcaatctcaa agacttgctg cttgctgcgc
     7801 ccgccggacg gctgaccacg ctgggtctcg accccggcta ccgcaacggc gtgaaatgcg
     7861 ccgtggtgga cgacaccggc aagctgctgg ataccgtcat cgtctatttg catcaagaaa
     7921 acaatatgtt ggcaacgctg tcgcgcctga ttaaacagca cggcgtgaag ctcatcgcca
     7981 tcggtaacgg caccgccagc cgtgaaaccg acaaaatcgc gggcgaactg gtgcgcggaa
     8041 tgccggaaat ggggctgcac aaaatcgtcg tttccgaagc cggcgcgtcg atttattccg
     8101 cgtccgaact ggcagcgcgc gagttccccg acttggacgt ttccctgcgc ggcgcggtgt
     8161 ccatcgcccg caggctgcaa gacccgcttg ccgagctggt caaaatcgac cccaaatcca
     8221 tcggcgtggg ccagtatcag cacgacgtga accaaagcca gctcgccaaa tcgctggacg
     8281 cggtggtcga agactgcgtg aacgccgtcg gcgtggacgt gaatactgcc tccgccccgc
     8341 tcttggcgcg gatttccggt ttgaatcaga cccttgccca aaacatcgtc gcctaccgca
     8401 atgaaaacgg cgcgttcgac agccgcaaaa aattgctgaa agtaccgcgt ttgggcgaaa
     8461 aaaccttcga gcaggcggca ggctttttgc ggattaacgg cggcacagag ccgttggacg
     8521 cgagcgccgt ccaccccgaa gcctatcccg tcgtcgccaa aatgctggcg caacaaggca
     8581 ttagcgccgc cgaactcatc ggcaaccgcg agcgcgtgaa gcaaatcaaa gcgtccgact
     8641 tcaccgacga acgcttcggc ctgccgacca ttttggacat cctgtccgaa ctggaaaaac
     8701 ccggccgtga tccgcgcggc gagtttcaga cggcatcgtt tgccgaaggt atccacgaaa
     8761 tcagcgactt gcaagtcggt atgatactcg aaggcgtggt ttccaacgtc gccaacttcg
     8821 gcgcgttcgt ggacatcggc gtccatcagg acggcttggt gcacatctcc gccctgtcca
     8881 acaagttcgt ccaagacccg cgcgaagtgg tgaaagctgg cgacgtggtg aaagtgaaag
     8941 tgctggaagt cgatgctgca cgcaaacgca tcgcgctgac catgcgcttg gatgacgaac
     9001 cgggcggcgc aaaacataaa atgccgtctg aaaaccgcag ccgcgaacgg acagccggcc
     9061 gcaaacccca acgcaacgac cgcgccccag ccaattcggc gatggcggat gcgtttgcga
     9121 agctgaagcg gtaaaataat cgaagagttt atggattttg acttatgcac acaccactta
     9181 cctatattga ccttttctca ggagcaggag gcctatcctt gggttttgaa caagccggat
     9241 tccaacaatt gctttctgtt gaaatggagt ctgattattg tcagacttac cgtaccaact
     9301 tcccccatca tcaattactg caaaaagatt taaccacact aaccgaacaa gatttaatca
     9361 attgtcttaa cggacaagca gttgatttga ttattggagg accaccttgt caaggtttta
     9421 gtatggcagg aaagattgga cggacattta cagatgaccc acgcaaccat ttatttaaag
     9481 agtttgtccg aatagttaaa attgtccaac catatttttt tgttatggaa aatgtagcgc
     9541 gactctatac acacaattca ggtaaaacac gtattgagat tattcaagca tttcagaata
     9601 tcggttattc ggtggaatgt aagatactga gtgcagccga tttcggtgtt cctcagatac
     9661 gtagccgagt gatatttatc gggaggaggg ataaaggcaa aatttccttt cccgaacctt
     9721 tgcagatttc ccatcagact gttggatcag caataggaca ttttccaaaa ctggctgctg
     9781 gcgaaagcaa tccacacgtt gcaaatcatg aagctatgaa tcattcggca caaatgttag
     9841 aaaaaatggc atttgttaaa aatggaggta accgtaacga tattcctgaa ccattacgtc
     9901 cgaaaacagg tgatatccgt aaatacatcc gttacaacag caacaaacca gccgtttgta
     9961 ttacaggaga tatgcgcaaa gtttttcact atgaacagaa tcgggcttta accgttcgtg
    10021 aattagctgc cttacaatct ttccctgata attttatttt ttgcggcagc aaaattgccc
    10081 agcagcaggt tggtaacgcc gtaccgcctt tattggcaaa agctattgct gaaagtattt
    10141 taaaaatgag tgaaaatgaa taagcaatat ccgaaaatta actatatcgg taataaagag
    10201 aaaatagctt cctggatttg tgaccagctt ccgtctgatg tagatacagt tgcagatgta
    10261 tttagtggag gctgttcctt tgcctatgaa gccaaaaaac gcggctatcg tgtgattact
    10321 aacgatattt tggcaattaa ttaccaaatt gctttagcat taatagaaaa caaccatgaa
    10381 acattaaatg acgatgatgg cgcaatgatt ttttcaggta gcccgcatgc cggttttatg
    10441 agtcagcgtt atgccgaaaa attctatttt cacgatgaat accaacaact tgatttgtac
    10501 cgtaaaaata tagggaaact ggataaccag tataaacgcg ctttggcgtt tactttaatg
    10561 cgtcgcgcca tgatacgtaa aatgccctat acggaagata tgcgcccggg cgataccgct
    10621 aatccttatg gcgcatccaa agcgatggtg gaacggatgt taaccgacat ccaaaaggcc
    10681 gatccgcgct ggagcgtgat tttgttgcgt tatttcaatc cgattggcgc gcacgaaagt
    10741 ggtttgattg gcgagcagcc aaacggcatc ccgaataatt tgttgcctta tatctgccaa
    10801 gtggcggcag gcaaactgcc gcaattggcg gtatttggcg atgactaccc tacccccgac
    10861 ggcacgggga tgcgtgacta tattcatgtg atggatttgg cagaagggca tatcgcggca
    10921 atgaaggcga aaggcggcct ttccggcgta catttgttca acttgggttc gggccgcgcc
    10981 tattccgtct tagaaatcat ccgtgccttt gaggccgcat ccggcttaaa tattccctat
    11041 caaatccaac cccgacgcgc cggagacttg gcgtgttcct ttgccgaccc gtcccatacc
    11101 aaacaagaga cgggctggga aaccaaacgc ggtttgaaac aaatgatgga ggattcgtgg
    11161 cgttgggtca gccgcaaccc cgacggatac ggggactaaa tgcaaaccgc aaacaaaaaa
    11221 accatcctcg ttaccggcgg tgcgggcttt atcgg
//
LOCUS       DAXIDM010000060        10789 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000060 DAXIDM010000000
VERSION     DAXIDM010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10789
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.060"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(64..677)
                     /locus_tag="ACFOAE_001349"
                     /pseudo
     CDS             complement(64..677)
                     /locus_tag="ACFOAE_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272072.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
     gene            complement(714..2864)
                     /gene="dinG"
                     /locus_tag="ACFOAE_001350"
     CDS             complement(714..2864)
                     /gene="dinG"
                     /locus_tag="ACFOAE_001350"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HFC6884820.1"
                     /translation="MLTDLEKNAIRDHYQNIGKNLPGFRPRASQREMIAAVANAFSRT
                     LAREEGGEPPKREGESIAVIEGPTGVGKSLAYLLAGGIMAQTRGKRLIVSSATVALQE
                     QLVDRDLPFLVEKSGLELSFALAKGRGRYLCPYKLYQLTQSNAQQNLLGFEAPAVLWD
                     SKPKPEELKLLRDIADEFSARRFNGDRDTWPEKIDDAIWLKVTNDRHGCLKTACPNRP
                     ECPFYLARDVLETVDVVVANHDLLLADISMGGGVILPAPENSFYCIDEAHHLPKKALS
                     RFAAEHSWNIAVWTLEKLPQLTGKIAALTDKAELANLADEAAASLLDSLHEWQFHLAE
                     EPSLSMGPSENDRRTNSEPTWLWEDGKIPEGLETTVSNTAIAARSLLKHVVGLNDALS
                     AARREKEQDGALLDRLTGEFGIFIVRIEQISAVWDLLSTVPLEGEEPLAKWITRRADD
                     KNDYIFNASPISSASHLANSLWRRAAGAVLTSATLQSLGNFNLMLRQTGLQWLPETTT
                     LALKSPFDFEKQGELYIPPIYASPKDPEAHTAAVIEWLPKLISPTEAIGTLVLFSSRK
                     QMQDVALRLPGDYLPLLLVQGELPKAVLLQKHHRAIEEGKASIIFGLDSFAEGLDLPG
                     TACVQVIIAKLPFAMPDNPIEKTQNRWIEQRGGNPFIEITVPEAGIKLIQAVGRLIRT
                     EQDYGRVTILDNRIKTQRYGQQLLAGLPPFKRIG"
     gene            2988..3191
                     /locus_tag="ACFOAE_001351"
     CDS             2988..3191
                     /locus_tag="ACFOAE_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884821.1"
                     /translation="MKYPLLLWIADMLLYRLLGGAEIECGRCPVPPMTDWQHFLPAMG
                     TVSAWVAVIWAYLMIESEKNGRY"
     gene            complement(3259..4560)
                     /locus_tag="ACFOAE_001352"
     CDS             complement(3259..4560)
                     /locus_tag="ACFOAE_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding domain-containing protein"
                     /protein_id="HFC6884822.1"
                     /translation="MPSETARPLYADTCAAHTLVWFRQNLRIRDNAALCAAVAEGLPI
                     IGIWIDDAETDNPRRAAFYRQSAAELAQGLAGRGIPLYTAASPAELVRLAVRLNIRTV
                     IADESHTFADKLADNALWHELDKHGIALTFVNDRAVFGKTDLIPDGGTAHTDFDRYRE
                     VWLDRFSKQPPAGPDLFAAYRQPFPENLSAPPPAALSDGIFLPQNGGETAAWRQWRRF
                     LEQADSYSVLKDFPSRKHTSLMGAYLSAGCISPRLLARESLERRLNAWADNIIRRDFF
                     LQLALQYADDDPSDGNPEHTLRLTLWQQGRTGIPIIDAAMRCLHKTGSLHPALRRLSA
                     DFFCHVLNLPRREGEIWFARQLTDFDAAINQGNWRLAASRHTCPDIAAASYRTDPDGT
                     FIKRHIPELAHLSADTVHTPWRFACSVDTHGYPAHPVAGIP"
     gene            complement(4550..5461)
                     /locus_tag="ACFOAE_001353"
     CDS             complement(4550..5461)
                     /locus_tag="ACFOAE_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFC6884823.1"
                     /translation="MDTLFSLKVFRQVVQSGGFTRAADALGISTAMASKHVSHLENTV
                     QAKLLHRNSRNLSLTEAGEEYYRQCSYALDTLDDAAQKAAGGTEKPQGLLRVTMPLWF
                     AGSQICNWLAEYRERYPEVTLELILDNRHVDLIAEGVDLALRVSQTLSPSLIARPLAE
                     IEFALLASPDFLRRNGVPETPEEVAGLPAVLPTYTNQQKLDLTRKSDGKKYRLELTPV
                     IRTDNTLMMREMIKAGACIGYQPLWAAEHDLRCGSLVRLLPEYTVPTDRLNAVYADRA
                     FLSAKVRSFIDFLNEKIASRKGCRNAV"
     gene            5569..5967
                     /locus_tag="ACFOAE_001354"
     CDS             5569..5967
                     /locus_tag="ACFOAE_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HFC6884824.1"
                     /translation="MSDCCNRIQPVLLSVLRIVTAYLFLLHGTSKIFAFPIEMGSGSP
                     GGLLLLAGILEIVGGILLVLGLFARPAAFVLSGQMAVAYFMAHASGNALFPIANGGES
                     AVLFCFVFLYIAAAGGGAWSLDRLFFKRKA"
     gene            6016..6621
                     /locus_tag="ACFOAE_001355"
     CDS             6016..6621
                     /locus_tag="ACFOAE_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFC6884825.1"
                     /translation="MTRQSLQQAAESRRSIYSLNKNLPVGKDEIVQIVEHAVLHTPSS
                     FNSQSARVVVLFGEEHDKVWQFVEDALCAVVPADSFEPTAQKLNLFKAGAATILFYED
                     QNVVKGLQEQFPAYAANFPVWADQANAMVQYAVWTTLAAVGVGANLQHYNPLPDAAIA
                     KAWNIPENWLLRAQMVIGGIEGAAGEKTFEPVAERLKVFGA"
     gene            6807..8918
                     /locus_tag="ACFOAE_001356"
     CDS             6807..8918
                     /locus_tag="ACFOAE_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HFC6884826.1"
                     /translation="MKISFHLALLPTLIIASFPVAAADTQDNGEHYTATLPTVSVVGQ
                     SDTSVLKGYINYDEAAVTRNGQLIKETPQTIDTLNIQKNKNYGTNDLSSILEGNAGID
                     AAYDMRGESIFLRGFQADASDIYRDGVRESGQVRRSTANIERVEILKGPSSVLYGRTN
                     GGGVINMVSKYANFKQSRNIGAVYGSWANRSLNMDINEVLNKNVAIRLTGEVGRANSF
                     RSGIDSKNVMVSPSITVKLDNGLKWTGQYTYDNVERTPDRSPTKSVYDRFGLPYRMGF
                     AHRNDFVKDKLQVWRSDLEYAFNDKWRAQWQLAHRTAAQDFDHFYAGSENGNLIKRNY
                     AWQQTDNKTLSSNFTLNGDYTIGRFENHLTVGMDYSREHRNPTLGYSRAFTASIDPYD
                     RASWPASGRLQPILTQNRHKADSYGIFVQNIFSATPDLKFVLGGRYDKYTFNSENKLT
                     GSSRQYSGHSFSPNIGAVWNINPVHTLYASYNKGFAPYGGRGGYLSINTSSSAVFNAD
                     PEYTRQYETGVKSSWLDDRLSTTLSAYQIERFNIRYRPDEQNDPYTWAVGGKHRSRGV
                     ELSAIGQIIPKKLYLRGSLGVMQAKVVEDKENPDRVGIHLNNTSNVTGNLFFRYTPTE
                     NLYGEIGVTGTGKRYGYNSRNKEVTTLPGFARVDAMLGWNHKNVNVTFAAANLFNQKY
                     WRSDSMPGNPRGYTARVNYRF"
     gene            9116..9775
                     /locus_tag="ACFOAE_001357"
     CDS             9116..9775
                     /locus_tag="ACFOAE_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFC6884827.1"
                     /translation="MKTAILIDGAFFIKRVRSLGLSQNPHDAKRIADLAFRYSMLHLK
                     YKINGTDQMGDLYRIFFYDCVPFEKKMHNPVSHRAIDFSKTPEAIFRRNLHTELKKKR
                     KLALRLGKLSDNTAWILKPQVMKNLLKNPSTQITENDVVLDVKQKGVDMRIGLDISSI
                     TLKKQADKIILFSGDSDFVPAAKLARREGIDFILDPMWNHVPPDLMEHIDGLKTKCPK
                     P"
     gene            9946..10641
                     /locus_tag="ACFOAE_001358"
     CDS             9946..10641
                     /locus_tag="ACFOAE_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC6884828.1"
                     /translation="MKLKTLALTSLTLLALAACSKQAETSVPADSVQSSSSAPAAPAE
                     LNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCAHLEPVLSEHIKTFKDDTYMRRE
                     HVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADIDTLKKWLSEQTAF
                     DGKKVLAAFEAPESQARSAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQ
                     LVDKVREEQKKPQ"
BASE COUNT         2434 a         2717 c         3075 g         2563 t
ORIGIN      
        1 gccgttttga ggccggggtc ggaataaccg ttttttgatg attttccctc cccggctgtg
       61 tcatcaaaac cccaattgcc tttccaaact ctccaccaga ttgtcatcca gttccaaagc
      121 ctgcgacagg cgggcgagga agacggtttc tttccgcgac aaatcggcac ataccagtct
      181 tgccgccaga taggcctccg ccgccaacgc ctcatcgttg ccgacggcgg cggcgatgtc
      241 ttcgatgctt gcgggcaggc ggtattcggc ggcgagccat gcagcagttt cggggtctgt
      301 gccgctttcc tgttcgatag tccggcgttc ggcttcgtct atcatgccgt ctgaagcggc
      361 ggtggctatc atggtgcgca atacggtgcg gctgtatgtt tcttcggttt ctccggcagg
      421 ttggaaatcg ctttgtgtta cggttgcccg ccctttgttt tgctgccaca tctgatagcc
      481 ccggtaggcg aggtagccca aagcggcggt cgaaccgatt ttggtgatgg ttttgcggtt
      541 tttaccgttc agcagcatgg aggcgacacc ggcaaccagc gcgcctccgc cgaatgaatt
      601 gagcgggctg tcggagaatg tgttgccttt ttttgaaccg tgcttaagac ttggttgagc
      661 agtcgggtaa agttcatgaa tttttccttt ctgttgcggg aagggcggta tgtttaccct
      721 atccttttaa acggcggcag gccggccaat aattgttggc cgtaccgctg tgttttgatg
      781 cggttgtcga ggatggttac gcggccgtag tcttgttcgg tgcggatgag gcggccgacg
      841 gcctggatga gtttgatgcc ggcttcgggg acggtgattt caataaaagg attgccgccg
      901 cgctgttcta tccagcggtt ttgggttttt tcgatggggt tgtcaggcat cgcaaacggc
      961 agcttggcga tgatgacttg cacgcaggcg gtgccgggca ggtcgagtcc ttcggcgaaa
     1021 ctgtcgagtc cgaagatgat gctggctttg ccttcttcta tggcccggtg gtgtttttgc
     1081 aggaggacgg ctttgggtaa ttcgccttgt acgagcaaga gcggcaggta gtctccgggc
     1141 aggcgcaggg cgacatcctg catttgtttg cgcgaggaaa acaagacgag cgtgccgatg
     1201 gcttcggtgg gcgaaataag cttgggcagc cattcgatga cggcggcggt gtgggcttcg
     1261 gggtctttgg ggctggcgta tatggggggg atgtagagtt cgccctgttt ttcaaagtca
     1321 aaggggcttt tgagggcgag ggtggtggtt tcgggcagcc attgcagccc ggtttggcgc
     1381 agcatcaggt tgaagttgcc caaggattgc agggtggcgg aagtcaatac cgcgcctgcc
     1441 gcgcgccgcc acaggctgtt ggcaaggtgg gatgcgctgc tgatggggct ggcgttgaaa
     1501 atgtagtcgt ttttgtcgtc ggcacggcgg gttatccatt ttgccagcgg ctcttcgcct
     1561 tcgaggggga cggtggagag caaatcccaa accgcgctga tttgttcgat acggacgatg
     1621 aagatgccga actcgccggt caggcggtcg aggagcgcgc cgtcctgttc tttttcgcgg
     1681 cgcgcggcgg aaagcgcatc gttcagcccg acaacgtgtt tgagcaggct gcgcgcagca
     1741 atggccgtat tggaaacggt ggtttcgagg ccttcgggga ttttgccgtc ttcccacagc
     1801 caagtcggtt cgctgttggt tcgtctgtcg ttttcagacg gccccatact taaagacggc
     1861 tcttccgcca aatggaactg ccattcgtgc aggctgtcga gcaaggatgc ggcggcttcg
     1921 tcggccaggt tggcaagttc ggctttatcg gtaagcgcgg caattttgcc ggtcagctgc
     1981 ggcagttttt ccagcgtcca aacggcaata ttccatgaat gttcggcggc aaaacggctg
     2041 agggcttttt tgggcaggtg gtgcgcttcg tctatgcaat agaaactgtt ttcgggcgca
     2101 ggcagaatca cgccgccgcc catactgatg tcggcaagca gaagatcgtg gttggcaacg
     2161 acgacatcga cggtttccaa gacatcgcgt gctaggtaaa acggacattc cggacggttg
     2221 ggacaggcgg ttttcaggca gccgtggcgg tcgttggtca ctttgagcca aatcgcgtca
     2281 tcgatttttt ccggccaagt gtcgcggtcg ccgttgaacc gtcgggcgga aaattcgtcg
     2341 gcgatgtcgc gcagcagctt caattcttcg ggcttgggtt tgctgtccca caagacggcg
     2401 ggggcttcaa agccgagcag gttttgctgg gcattgcttt gcgtcagttg atagagtttg
     2461 taggggcaga gatagcggcc gcgccctttg gcaagcgcga agctcagttc caaaccgctt
     2521 ttttcgacca aaaacggcag gtcgcggtct accaactgct cctgcaaggc aaccgttgcg
     2581 ctgctcacaa tcagccgctt gccgcgcgtc tgcgccatga tgccgcccgc cagcaggtag
     2641 gcaagcgatt tgcccacgcc ggtcggccct tcgattacgg cgatgctctc gccctcgcgc
     2701 ttgggcggct cgccgccttc ttcgcgcgcc aacgtccgcg aaaaagcgtt ggcaaccgcc
     2761 gcaatcattt cccgctgcga agcgcgcgga cggaaaccgg gcaggttttt gccgatgttt
     2821 tggtaatggt cgcggatggc gtttttttct aaatcggtga gcatggcgtt ttgtacggcg
     2881 gtagaagtgg gcttatttta acattgcacg gaagcggtac aatatcgttg tcggaatggg
     2941 gggtgaggtg aatcgtgcgg acgtggttgg ttttttggtt gcagcgtttg aaatacccgt
     3001 tgttgctttg gattgcggat atgttgctgt accggttgtt gggcggcgcg gaaatcgaat
     3061 gcggccgttg ccctgtgccg ccgatgacgg attggcagca ttttttgccg gcgatgggaa
     3121 cggtgtcggc ttgggtggcg gtgatttggg catacctgat gattgaaagt gaaaaaaacg
     3181 gaagatattg agtcattcgg acgcaatgcc gtctgaaacg gaagttcaga cggcatttgt
     3241 tttaggttgc cgtaccgctt agggaatacc ggcgacagga tgggcgggat agccgtgggt
     3301 atcgaccgaa caggcaaacc gccaaggcgt gtggacggtg tcggcggaca ggtgggcgag
     3361 ttcgggaatg tgccgtttga taaaagtacc gtccgggtcg gtacggtatg aggcggcggc
     3421 aatgtcgggg caggtgtgcc gtgaggcggc aagccgccag ttgccttggt tgattgccgc
     3481 atcgaaatcg gtcagctgcc gggcaaacca tatctcgcct tcgcggcggg ggaggtttaa
     3541 aacgtggcag aaaaaatccg cgctcaagcg tctcagggcg gggtggaggc tgccggtttt
     3601 gtgcaaacag cgcatcgcgg catcgataat cggaatgccg gtccggccct gctgccaaag
     3661 cgtcaggcgc agggtgtgtt ccggattgcc gtctgaaggg tcgtcatccg cgtactgcaa
     3721 ggcaagttga aggaaaaaat cgcggcggat gatgttgtcc gcccacgcat tcagacggcg
     3781 ttcgaggctt tcccgtgcga gcaggcgcgg cgagatgcag ccggcactca aatacgcgcc
     3841 catcagcgaa gtgtgtttgc gtgaggggaa atcctttaaa acggagtagg aatccgcctg
     3901 ttcgagaaac cgccgccact gccgccaagc cgccgtttcg ccgccgtttt gcggcaggaa
     3961 gatgccgtct gaaagggcgg caggcggcgg ggcggaaagg ttttcgggga agggttggcg
     4021 gtatgccgcg aataggtccg gaccggcggg gggctgcttg gaaaagcggt cgagccatac
     4081 ttcgcggtag cggtcgaaat cggtgtgtgc cgtgccgccg tcgggtatca ggtcggtttt
     4141 gccgaaaacg gcgcggtcat tgacgaaggt taacgcgatg ccgtgtttgt ccaattcatg
     4201 ccaaagggcg ttgtcggcga gtttgtcggc aaaagtatgg gattcgtcgg cgatgacggt
     4261 gcggatattg aggcggacgg cgagccggac gagctcggca ggcgatgccg ccgtgtagag
     4321 cgggatgccg cgccctgcaa gcccttgggc gagttcggcg gcggattggc ggtagaacgc
     4381 ggcgcggcga gggttgtctg tttcggcatc gtcaatccaa atgccgataa tgggcaaacc
     4441 ttcggcaacg gcggcgcata aggcggcgtt gtcgcggatg cggaggtttt ggcggaacca
     4501 gacgagcgtg tgtgcggcgc acgtgtccgc ataaaggggg cgggcggttt cagacggcat
     4561 ttcggcagcc tttcctgctg gcgatttttt cgttcagaaa atcgatgaag ctgcggactt
     4621 tcgcgcttaa gaacgccctg tccgcataaa cggcattcag gcggtcggtc gggacggtat
     4681 attcgggcag cagcctcacc agcgagccgc agcgcaaatc gtgttccgcc gcccaaagcg
     4741 gctgataacc gatgcacgcg cccgccttaa tcatttcgcg catcatcagc gtgttgtcgg
     4801 tacggatgac gggggtcagt tcaagccggt attttttgcc gtccgatttg cgggtgaggt
     4861 cgagtttctg ctggttggtg taggtcggca ggacggcggg cagccccgcc acttcttccg
     4921 gcgtttccgg tacgccgttg cgcctcagga aatcgggcga ggcgagcagg gcaaattcga
     4981 tttccgccag cgggcgcgca atcagcgacg gggacagggt ttgggaaacg cgcaacgcca
     5041 aatccacgcc ttcggcaatc aaatcgacgt ggcggttgtc caaaatcagt tctaatgtca
     5101 cttcgggata acgttcgcgg tattccgcca gccagttgca tatctggctg ccggcaaacc
     5161 acagtggcat cgttacgcgc agcagcccct gcggtttttc cgtccccccg gcggcttttt
     5221 gcgcggcatc gtcgagcgtg tcgagcgcgt aactgcattg ccggtagtat tcttccccgg
     5281 cttcggtcag gctgaggttg cggctgttgc ggtgcaggag tttggcttgg acggtgtttt
     5341 ccaagtggct gacgtgtttg cttgccattg cggtggagat gccgagcgcg tcggcggcgc
     5401 gggtgaagcc gccgctttgg acgacttggc ggaaaacctt gaggctgaac agggtgtcca
     5461 tattttcttg tgtggaaaag ttgtatcaat aaaagcagta tatatttgaa aaggggaaac
     5521 atctatactc taccgcctga aatgaagaca aatatcaaag gagcttttat gtccgattgc
     5581 tgcaaccgta tccaaccggt tttgctttct gttttgcgta tcgtaaccgc ttacctgttt
     5641 ttgttgcacg gtacgtcgaa aatcttcgcc ttccccattg aaatgggcag cggttcgccc
     5701 ggcgggctgt tgctgcttgc cggtatttta gaaattgtcg gcggcatttt gctggtgttg
     5761 ggcctgtttg cgcgccctgc cgcgtttgtt ttgtccggcc agatggcggt tgcctatttt
     5821 atggcgcacg cttccggaaa tgctttgttc ccgattgcca acggcggcga gtccgcagtg
     5881 ctgttctgct tcgtattcct ctatatcgcg gcggcgggcg gcggagcatg gtcgctggac
     5941 aggctgtttt tcaagcgtaa agcctgaatc agactgccta aagtgtattt tgttgaatgt
     6001 ttttgaggaa aagaaatgac ccgtcaatct ctgcaacagg ctgccgaaag ccgccgttcc
     6061 atttattcgt taaataaaaa tctgcccgtc ggcaaagatg aaatcgtcca aatcgtcgaa
     6121 cacgccgttt tgcacacacc ttcttcgttc aattcccaat ctgcccgtgt ggtcgtgctg
     6181 tttggcgaag agcatgataa ggtgtggcaa tttgtcgaag acgcgctgtg tgccgtcgtg
     6241 cctgccgaca gttttgaacc gaccgcgcaa aaattgaacc tgtttaaggc gggtgcggca
     6301 actattttgt tttatgaaga tcaaaatgtc gtcaaaggtt tgcaggagca gttccctgct
     6361 tatgccgcca actttcccgt ttgggcggac caggcgaacg cgatggtgca gtatgccgtt
     6421 tggacgacac ttgccgcggt cggcgtaggt gcaaacctgc aacattacaa tcccttgccc
     6481 gatgcggcga ttgccaaagc gtggaatatc cccgaaaact ggttgttgcg cgcacaaatg
     6541 gttatcggcg gtattgaagg ggcggcaggt gaaaagacct ttgaaccagt tgcagaacgt
     6601 ttgaaagtgt tcggcgcata atttcgcggt caaaaaaatg ccgtctgaac cctgttcaga
     6661 cggcattttt cagtatcagg cggcgagttt tccgcattct gagacctttg tttacaaata
     6721 tcatgttcaa tatagttaaa agaaattatt ctcatttcct ccgtgaggca atataattcg
     6781 gttgttttgt taaattgagt ataaaaatga aaatatcatt tcatttagct ttattaccca
     6841 cgctgattat tgcttccttc cctgttgctg ccgccgatac gcaggacaat ggtgaacatt
     6901 acaccgccac tctgcccacc gtttccgtgg tcggacagtc cgacaccagc gtactcaaag
     6961 gctacatcaa ctacgacgaa gccgccgtta cccgcaacgg acagctcatc aaagaaacgc
     7021 cgcaaaccat cgatacgctc aatatccaga aaaacaaaaa ttacggtacg aacgatttga
     7081 gttccatcct cgaaggcaat gccggcatcg acgctgccta cgatatgcgc ggcgaaagca
     7141 ttttcctgcg cggttttcaa gccgacgcat ccgatattta ccgcgacggc gtgcgcgaaa
     7201 gcggacaagt gcgccgcagt actgccaaca tcgagcgcgt ggaaatcctg aaaggcccgt
     7261 cttccgtgct ttacggccgc accaacggcg gcggcgtcat caacatggtc agcaaatacg
     7321 ccaacttcaa acaaagccgc aacatcggtg cggtttacgg ttcgtgggca aaccgcagcc
     7381 tgaatatgga cattaacgaa gtgttgaaca aaaacgtcgc catccgtctc accggcgaag
     7441 tcgggcgcgc caattcgttc cgcagcggca tagacagcaa aaatgtcatg gtttcgccca
     7501 gcattaccgt caaactcgac aacggcttga agtggacggg gcaatacacc tacgacaatg
     7561 tggagcgcac gcccgaccgc agtccgacca agtccgtgta cgaccgcttc ggactgcctt
     7621 accgcatggg gttcgcccac cggaacgatt ttgtcaaaga caagctgcaa gtttggcgct
     7681 ccgaccttga atacgccttc aacgacaaat ggcgtgccca atggcagctc gcccaccgca
     7741 cggcggcgca ggattttgat catttctatg caggcagcga aaatggcaac ttaatcaaac
     7801 gtaactacgc ctggcagcag accgacaaca aaaccctgtc gtccaatttc acgctaaacg
     7861 gcgactacac catcggccgt tttgaaaacc acttgaccgt aggcatggat tacagccgcg
     7921 aacaccgcaa cccgacctta ggttacagcc gcgcctttac tgcttccatc gatccatacg
     7981 accgagcaag ctggccggct tcgggcagat tgcagcctat cctcacccaa aaccgccaca
     8041 aagccgactc ctacggcatc tttgtgcaaa acatcttctc cgccacgccc gatttgaaat
     8101 tcgtcctcgg cggtcgttac gacaaataca cctttaattc cgaaaacaaa ctcaccggca
     8161 gcagccgcca atacagcgga cactcgttca gccccaacat cggcgcagtg tggaacatca
     8221 atcccgtcca cacactttac gcctcgtata ataaaggctt cgcgccttat ggcggacgcg
     8281 gcggctattt gagcatcaac acgtcgtctt ccgccgtgtt caacgccgac cccgagtaca
     8341 cccgccaata cgaaaccggt gtgaaaagca gttggctgga cgaccgcctc agcactacgt
     8401 tgtctgccta ccaaatcgaa cgcttcaata tccgctaccg ccccgacgag caaaatgatc
     8461 cctacacttg ggcagtcggc ggcaaacacc gttcgcgcgg cgtggaattg tccgccatcg
     8521 ggcaaatcat ccccaaaaaa ctctatctgc gcggttcgtt gggcgtgatg caggcgaaag
     8581 tcgttgaaga caaagaaaat cccgaccgag tgggcatcca tttgaataac accagcaacg
     8641 ttaccggcaa cctgtttttc cgttataccc cgaccgaaaa cctctacggc gaaatcggcg
     8701 taaccggtac aggcaaacgc tacggttaca actcaagaaa taaagaagtg actacgcttc
     8761 caggctttgc ccgagttgat gccatgcttg gctggaacca taaaaatgtt aacgttacct
     8821 ttgccgcagc caatctgttc aatcaaaaat attggcgttc ggactctatg ccgggtaatc
     8881 cgcgcggcta tactgcccgg gtaaattacc gtttctgatg aaatcaggca aaggccgtct
     8941 gaaaatcctg ataatccgta aattcagcat acgaactttt tgacaggctt tatctacatc
     9001 agtataatcc aaaaagaaat agtgcccttg gcagtacgca ttacccatta aatcatagcg
     9061 ggtatgccga tcccaagggc ttttttatat ctttgacaaa tataggggaa gcaatatgaa
     9121 aaccgccatt ttgattgacg gtgcattttt tattaagcgg gtacggtcat taggcctgtc
     9181 tcaaaatcca cacgatgcaa aaagaattgc tgatttggct ttccgatatt cgatgctgca
     9241 tctgaaatat aaaatcaacg gcacagatca aatgggtgat ttatatagaa ttttctttta
     9301 cgactgcgtg ccgtttgaaa agaaaatgca caatcccgta tctcatcgtg ccatagattt
     9361 ttcaaagact ccggaagcca tatttcgtcg caatctgcat accgaattga agaagaagcg
     9421 taaattagcg ttacgtttag gcaagctgtc ggacaataca gcatggatat taaaacccca
     9481 agtcatgaaa aatcttctga aaaacccgtc aactcaaatt acggaaaacg atgtcgtgct
     9541 cgatgttaaa caaaaaggtg tagatatgcg tataggcttg gatatttcat ctattacctt
     9601 aaaaaaacaa gccgataaaa tcatcttgtt ttctggtgat tccgattttg tcccagcagc
     9661 caaattagcc agacgggaag gtatcgattt tattcttgat cctatgtgga atcatgtccc
     9721 acctgactta atggaacaca tcgacggatt gaagacaaaa tgtccgaaac cgtaaattac
     9781 tagaacaaag gccgtctgaa aataaggcta attatctaag ccatatttca gatggccttt
     9841 ataaaggctg aaataaaact aaacacattt tttcactcaa atcgaacacg ccttcaataa
     9901 aatgtcataa aatccgcaca ttaatctgac acacaagaga tacctatgaa actgaaaacc
     9961 ttagctttga cttcattgac cctgttggcg ttggccgctt gtagcaaaca ggctgaaacc
    10021 agcgttccgg cagacagcgt ccaaagcagc tcatctgctc cggcagcccc tgctgagttg
    10081 aacgaaggtg tgaactacac tgtattgtct acgcctattc cgcaacagca ggccggtaaa
    10141 atcgaagtat tggaattttt cggctacttc tgcccgcatt gcgcccatct tgagccggtc
    10201 ttgagcgagc acatcaaaac gtttaaagac gatacctata tgcgccggga gcatgtcgtg
    10261 tggggtgatg aaatgaaacc tttggcacgt ttggcggccg cagtggaaat ggccggtgaa
    10321 tcagataaag ccaacagcca tattttcgat gcgatggtta atcaaaaaat caatctggct
    10381 gatatcgata ccctgaaaaa atggctgtcc gagcaaacag cgtttgacgg caaaaaagta
    10441 ttggctgcat ttgaggctcc tgaaagccaa gcgcgttcgg ctcaaatgga agagttgacc
    10501 aataaattcc aaatcagcgg cacaccgact gtgatcgtcg gcggcaaata ccaagttgaa
    10561 tttaaagact ggcagtctgg tatgaccacg attgaccagt tggtggataa agtacgcgaa
    10621 gagcagaaaa agccgcaata agttgaggat tgaatgagta aaggccgtct gaaaatagga
    10681 tttcagacgg ccttttgtat ttaggcttta tagaagagat gattgcttaa agccttatgg
    10741 ttttaaatca gaatatatag tggattaaca aaaaccagta cggcgttgg
//
LOCUS       DAXIDM010000061        10268 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000061 DAXIDM010000000
VERSION     DAXIDM010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10268
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.061"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(64..1206)
                     /locus_tag="ACFOAE_001359"
     CDS             complement(64..1206)
                     /locus_tag="ACFOAE_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFC6884829.1"
                     /translation="MNTLYTLFATCPRGLETVLSQELGSLGCTDVQAFDGGVSCRGGL
                     EQAYAANLHSRTASRILLRLTKGTYRNERDIYKLAKNINWFNWFTLQQTFKVKVEAKR
                     ANVKSIQFVGLTVKDAVCDAFRDIYDARPSVDKAAPDVRIHAFLDERNVEIFIDTSGE
                     ALFKRGYRLDTGEAPLRENLAAGLLLSAGYDGTQPFQDPFCGSGTIAIEAAWIAARRA
                     PGMMRRFGFEKLQNFDKTLWSDLRRRAEAQVKPAFAPISGSDSDRRIIQTALANARSA
                     GVDDIVSFSVADAQSVRPNGVGGIMVSNPPYGVRLEEVRALQALYPQLGTWLKKYYAG
                     WLAAMFTGDREMPKFMRLSPKRKILLYNGNLDCRLFLIDMVQGSNR"
     gene            complement(1255..1677)
                     /locus_tag="ACFOAE_001360"
     CDS             complement(1255..1677)
                     /locus_tag="ACFOAE_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884830.1"
                     /translation="MNKNRKLLLAALLLIAFAAVKLVLLQWWQAQQPQAVAAQCDLTE
                     GCTLPDGSRVRAAAVSTKKPFDIYIEHAPVGTEQVSISFSMKNMDMGFNRYMFERQPS
                     GTWQAVRIRLPICVEGRRDFTADITIGSRTFQTAFTAE"
     gene            complement(1670..2479)
                     /locus_tag="ACFOAE_001361"
     CDS             complement(1670..2479)
                     /locus_tag="ACFOAE_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFC6884831.1"
                     /translation="MIQDTRPLIRVVAGILLDSDGNYLLSSRPEGKPYAGYWEFAGGK
                     VEAGETDFQALQREFEEELGIRILAATPWLTKIHSYEHARVCLKFLWVNPDQWTGEPQ
                     SREGQEWSWQKAGDFTVAPMLPANGALLRSLSVPRRLYGSLKTGLHGENSMGAYRVLP
                     LGSAEGSGANVLMEAAQWQDRPEYAGSVWMMVQTREQWRQAQEKGVDVVVWRVGNAAQ
                     AAAVDEVLKHGVSVPLVLAANGQTVARYGKLWLGLGAHVVVRDETIGKNHE"
     gene            complement(2561..2938)
                     /gene="acpS"
                     /locus_tag="ACFOAE_001362"
     CDS             complement(2561..2938)
                     /gene="acpS"
                     /locus_tag="ACFOAE_001362"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFC6884832.1"
                     /translation="MIYGIGTDIVSLKRIIRLNKKFGQAFAGRILTPEELLEFPQAGK
                     PVNYLAKRFAAKEAFAKAVGTGIRGAVSFRNIGIGHDALGKPEFFYGPALSKWLEEQG
                     ISRVSLSMSDEEDTVLAFVVAEK"
     gene            complement(3138..3905)
                     /locus_tag="ACFOAE_001363"
     CDS             complement(3138..3905)
                     /locus_tag="ACFOAE_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013107841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFC6884833.1"
                     /translation="MQEIIQSIVFIAAAILHGITGMGFPMLGTTALAFIMPLSKVVAL
                     VALPSLLMSLLVLCSNNKKGFWQEIVYYLKTYKLLAIGSVVGSIFGVKLLLILPVSWL
                     LLLMAIITLYYSVNGILNVCAKAKNIQVVANNKNMVLFGFLAGIIGGSTNAMSPILLI
                     FLLSETENKNRIAKSSNLCYLLAKIVQIYMLRDQYWLLNKSEYGLIFLLSVLSVIGLY
                     VGIRLRTKISPNFFKMLIFIVLLVLALKIGHSGLIKL"
     gene            complement(3915..4694)
                     /locus_tag="ACFOAE_001364"
     CDS             complement(3915..4694)
                     /locus_tag="ACFOAE_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="HFC6884834.1"
                     /translation="MNQKYILSANNNSLIEEIHNTVQSIGYCIVRGLNLNHLDDSRRN
                     KKLFDFLSQLGMLTNHKDDGFKSIFWDIKYRGDDYVINNDITFSEDVGECPLHSDSSF
                     SESPESYLVMYVVKSANDGGNSLFLSSSDIVNQLSKTETGKKHLKTLTGNLYPFKTPT
                     SFDKKQGVIWGNILSLNTQMIRFRSDCIYKGIEENRNKVSKEMVLALDYLVKIIKNAS
                     DIQEFSAQDDGLIIIDNVNGLHAGTDYTDKNRHYIRARITV"
     gene            complement(4741..5469)
                     /gene="pdxJ"
                     /locus_tag="ACFOAE_001365"
     CDS             complement(4741..5469)
                     /gene="pdxJ"
                     /locus_tag="ACFOAE_001365"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033856 - pyridoxine 5'-phosphate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HFC6884835.1"
                     /translation="MLLGVNIDHIATVRNARGTTYPSPVEAALVAETHGADLITMHLR
                     EDRRHIKDADVFAVKNAIRTRLNLEMALTEEMLENALNVMPEDVCLVPEKRQEITTEG
                     GLDVLAQQEKIAEFTKILTDAGIRVSLFIDADDRQIQAAYDVGAPVVELHTGAYADAR
                     SHAEQLKQFERLQNGAHFAGDLGLVVNAGHGLTIHNVTPIAQILAIRELNIGHSLIAQ
                     ALFLGLPEAVRQMKEAMFRARLLP"
     gene            complement(5522..6265)
                     /gene="recO"
                     /locus_tag="ACFOAE_001366"
     CDS             complement(5522..6265)
                     /gene="recO"
                     /locus_tag="ACFOAE_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFC6884836.1"
                     /translation="MSEHRVNHEPVFLLASSPWRESSLRVEAFSRRYGRVALLARSAR
                     KRQSELRGVLVPFVPVSASWYGSQELKTLHRAEWIGGWPQPQGRALFSGLYVNELMLK
                     LTVREDPLPELYDALAEVMEAVCREANHIADLRRFEWKLLNALGVAPDLHADGTGGDI
                     LADKTYRLMPEEAVMPVCEDADALSHEAGAIVEGQSLIDLREGSFRTAESLQQALKIT
                     RLFIRHLLPEGLKSRQVLEQIRQFDRNTA"
     gene            complement(6299..7426)
                     /gene="pheA"
                     /locus_tag="ACFOAE_001367"
     CDS             complement(6299..7426)
                     /gene="pheA"
                     /locus_tag="ACFOAE_001367"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFC6884837.1"
                     /translation="MLECTINYCSGEIMSQTIDELLLPHRNAIDTIDAEILRLLNERA
                     QHAHAIGELKGTGAVYRPEREVAVLRRIQDLNKGPLPDESVARLFREVMSECLAVERP
                     LTIAYLGPQGTFTQQAAIKHFGHAAHTMACPTIDDCFKQVETRQADYLVAPVENSTEG
                     SVGRTLDLLAVTALQACGEIVLRIHHNLLRKNNGSTEGIAKVFSHAQALAQCNDWLGR
                     HLPNAERIAVSSNAEAARLVAESDDGTVAAIAGRTAAEIYGLDMVAECIEDEPNNTTR
                     FLVMGHHETGASGSDKTSLAVSAPNRAGAVASLLQPLTESGISMTKFESRPSKSVLWE
                     YLFFIDIEGHRRDAQIQTALERLGERASFVKVIGSYPTAVL"
     gene            complement(7465..8697)
                     /locus_tag="ACFOAE_001368"
     CDS             complement(7465..8697)
                     /locus_tag="ACFOAE_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HFC6884838.1"
                     /translation="MPSAHYPEMSEKLMAVLMAMLVTLMPFSIDAYLPAIPEMAQSLN
                     ADVHRIEQSLSLFMFGTAFGQVVGGSVSDIKGRKPVALTGLAVYCLAVAAIVFASSAE
                     QLLNLRVVQAFGAGMTVVIVGAMVRDYYSGRKAAQMFALIGIILMVVPLVAPMVGALL
                     QGLGGWQAIFVFLAAYSLVLLGLVQYFLPKPAVGGKIGRDVFGLVAGRFKRVLKTRAA
                     MGYLFFQAFSFGSMFAFLTESSFVYQQLYRVTPHQYAWAFALNIITMMFFNRVTAWRL
                     KTGVHPQSILLWGIVVQFAANLSQLAAVLFFGLPPFWLLVACVMFSVGTQGLVGANTQ
                     ACFMSYFKEEGGSANAVLGVFQSLIGAGVGMAATFLHDGSATVMAATMTASTSCGIAL
                     LWLCSHRAWKENGQSEYL"
     gene            complement(9217..10071)
                     /locus_tag="ACFOAE_001369"
     CDS             complement(9217..10071)
                     /locus_tag="ACFOAE_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HFC6884839.1"
                     /translation="MFYQILALIIWSSSFIAAKYVYGGIDPALMVGVRLLIAALPALP
                     ACRRHVGKIPREEWKPLLIVSFVNYVLTLLLQFVGLKYTSAASASVIVGLEPLLMVFV
                     GHFFFNDKARAYHWICGAAAFAGVALLMAGGAEEGGEVGWFGCLLVLLAGAGFCAAMR
                     PTQRLIARIGAPAFTSVSIAAASLMCLPFSLALAQSYTVDWNVGMVLSLLYLGLGCGW
                     YAYWLWNKGMSRVPANVSGLLISLEPVVGVLLAVLILGEHLSPVSALGVFVVIAATLV
                     AGRLSHQK"
BASE COUNT         2479 a         2777 c         2655 g         2357 t
ORIGIN      
        1 atcggctgga tattaaaaaa agccgtctga acatttttca gacggctttt ttgtacactt
       61 tcctcaacgg ttcgatccct gcaccatatc aatcaggaac aggcggcaat cgaggttgcc
      121 gttataaagc agaattttgc gttttggcga caggcgcatg aatttgggca tttcccgatc
      181 tccggtaaac attgccgcca accagcctgc gtaatatttc ttcaaccacg tccccaactg
      241 cggataaagc gcctgcaagg cgcggacttc ctcaaggcgc acgccgtagg gcggattgga
      301 caccataatg ccgcccacgc cgttcggacg gacggattgc gcgtcggcaa cgctgaagga
      361 aacgatgtcg tccaccccgg cactgcgtgc gttggccaat gccgtctgaa tgatgcggcg
      421 gtcgctgtcg ctgcccgaaa tcggtgcaaa agccggttta acctgcgctt cggcacggcg
      481 gcgcaaatcc gaccacagcg ttttatcgaa attttgcagt ttttcaaaac cgaaacggcg
      541 catcataccc ggcgcgcggc gggcggcaat ccaagcggct tcgatagcaa tcgtgccgct
      601 gccgcaaaac gggtcttgaa acggctgcgt gccgtcgtag cctgccgaga gcagcaatcc
      661 ggcggcaagg ttttcgcgca gcggggcttc gccggtatcg agacggtagc cgcgtttgaa
      721 cagggcttcg cccgaagtgt cgatgaagat ttcgacattg cgttcgtcca aaaaggcgtg
      781 gatgcgaaca tcgggcgcgg ctttgtccac gctcggacgt gcgtcgtaaa tgtcgcggaa
      841 agcgtcgcag acggcatctt tgacggtcag tccgacaaat tggatgctct taacgttggc
      901 acgctttgcc tcgactttga ctttgaacgt ctgctgtaaa gtaaaccaat taaaccagtt
      961 gatatttttg gcgagtttgt agatgtcgcg ctcattgcgg tatgtccctt tggtcaagcg
     1021 cagcaggata cggctggcag tacgcgaatg caggttggcg gcgtaggcct gttccaatcc
     1081 gccgcggcag gaaacgccgc cgtcaaacgc ttgaacatcg gtacagccga ggcttccgag
     1141 ttcttgagat aaaacggttt ccaagccgcg cgggcaggtg gcgaaaagtg tatataaagt
     1201 attcataacg tgtcctttcc ggacggatgt tccggcaatg gcggattgaa aggtttattc
     1261 ggcggtaaat gccgtctgaa atgtccggct gccgattgta atgtccgccg taaaatcgcg
     1321 cctgccttcg acacagatgg gcaggcggat gcgtactgcc tgccaagtcc ccgacggttg
     1381 ccgctcgaac atatagcggt tgaaacccat atccatattt ttcatactga agctgatgct
     1441 gacctgttcc gtgccgacgg gcgcgtgttc gatataaata tcaaacggtt ttttggttga
     1501 aacggcggcg gcgcggacgc ggcttccgtc cggcagcgtg caaccctcgg tcaaatcgca
     1561 ttgcgccgcc acggcttgcg gctgctgcgc ctgccaccat tgcaacaaaa cgagcttgac
     1621 ggcggcaaag gcaatcagca gcagtgcggc aagcagtaat ttacggtttt tattcatgat
     1681 tcttccctat tgtttcatcc cttaccacca cgtgcgcccc caatccgagc catagttttc
     1741 cataacgtgc aaccgtctgt ccgtttgctg caagtacgag cggcacggat acgccgtgct
     1801 tcaacacttc gtctaccgct gcggcttgtg cggcattacc gactcgccag acgaccacat
     1861 ccacgccctt ttcctgcgcc tgccgccatt gttcgcgggt ctgcaccatc atccacacgc
     1921 tgccggcgta ttcgggtctg tcctgccatt gcgccgcctc catcaaaacg ttcgcaccgc
     1981 ttccctctgc cgaacccaaa ggcaggacgc ggtacgcgcc catactgttt tctccgtgca
     2041 aacccgtttt caggctgccg tacaaacggc gcgggacgga cagcgaacgc aaaagcgcgc
     2101 cgttggcggg cagcatgggg gcaacggtaa aatcacccgc cttctgccaa gaccattcct
     2161 gcccttcgcg ggattgcggt tcgcccgtcc attggtcggg gttgacccat aggaatttca
     2221 ggcagacgcg ggcgtgttcg taggaatgga ttttggtcaa ccaaggcgtg gcggcgagga
     2281 tgcggatgcc gagttcttct tcaaactcgc gttgcagggc ttggaagtcg gtttcgcccg
     2341 cttcgacctt gccgccggca aattcccaat atccggcata gggtttgcct tcggggcgcg
     2401 agctgagcag gtagttgccg tctgaatcga gcaggatgcc ggcaacgacg cggataaggg
     2461 ggcgggtgtc ttgaatcatg gcgggtacgc ggttggtcgg tcggagtgca aatgagggat
     2521 gggcaatgcc gtcaacgggt tttccgcatt tcagacggca ttatttttcg gcaacgacaa
     2581 acgccaatac ggtgtcttct tcgtcgctca tgctgaggct gacgcggctg atgccttgtt
     2641 cctccagcca tttggacagg gcggggccgt agaaaaattc gggcttgccc aatgcgtcat
     2701 gcccgatgcc gatgttgcgg aaggaaaccg cgccgcgtat gcccgtgccg acggctttgg
     2761 caaaggcttc tttggcggca aagcgtttgg cgaggtagtt gacgggtttg cccgcttgcg
     2821 gaaattcaag cagctcttcc ggagtgagga tgcgcccggc aaacgcctgt ccgaattttt
     2881 tgtttaagcg gatgatgcgc ttgagggaaa caatgtctgt gccgatgccg taaatcatat
     2941 ttgcgctcct tcgcccttgg ttgcgggtag tgatgaatgt gatgatgaat gccgtcaatt
     3001 tcttggggcg ttaaaatggc gtgaatatcc actttcgggg ttttgtcggt aacaattttt
     3061 attgtaacct tttgcatttg aaattctaaa acatcgtgcc aattatttaa taaggagtta
     3121 aggcatttaa taatgaatta aagtttgatt aaacccgaat gcccgatttt cagagccaat
     3181 accaataaaa caataaaaat taacatttta aaaaaatttg ggctaatctt agtccttaac
     3241 cgaattccaa catacaatcc aataacagac aatacggaca gtaaaaatat taaaccgtat
     3301 tcactcttat ttaataacca atactggtct cttagcatat atatttgaac aattttcgcc
     3361 aaaagatagc atagattgct tgattttgcg atacgatttt tattctctgt ttcgctaagc
     3421 aaaaatatta acaatatggg agacatggca ttggttgaac cgccgatgat gcctgccaaa
     3481 aacccaaaaa gaaccatatt cttattattg gcaactactt gaatattttt tgcttttgca
     3541 catacattta aaataccatt gacagaataa tacaatgtaa tgattgccat cagtaaaagc
     3601 agccaagaca ctggaagtat caaaagcaac ttcaccccaa aaatgctgcc aacgacgctg
     3661 ccgatagcaa gcaatttata ggtttttaaa taataaacaa tctcttgcca aaaacccttt
     3721 ttgttattgc tgcatagaac caacaagctc attaacaggc ttggtaatgc caccaaggca
     3781 acaaccttag acaatggcat gataaaagcc aatgcggttg taccgagcat cggaaatccc
     3841 atgcctgtaa ttccgtgcag tattgcggca gcaataaaaa caatagattg tattatttct
     3901 tgcataaccg tcctttatac agtaattctt gctctaatat aatgcctgtt tttatccgta
     3961 taatcagttc cggcatgcaa accattgaca ttgtcaataa taatcaaacc atcatcttgt
     4021 gcagaaaatt cttgaatatc actcgcattt tttataatct ttacaagata atcaagtgca
     4081 agtaccattt cctttgatac tttatttcta ttttcttcaa tacctttata gatacaatca
     4141 cttctaaatc taatcatttg tgtattgagc gataagatat taccccatat cacaccttgt
     4201 tttttatcaa atgatgttgg tgttttaaat ggatataaat tgcccgttaa tgtttttaag
     4261 tgttttttac cggtttctgt tttagataac tgattgacaa tatctgatga acttaaaaat
     4321 agagaattac ctccgtcatt ggctgatttt actacataca taaccaaata actttccggg
     4381 ctttcactaa aagatgaatc actatgaagt ggacattctc caacatcttc cgagaaagtt
     4441 atatcattat ttattacata gtcatcgccg cgatatttaa tatcccaaaa tatagattta
     4501 aaaccatcgt ctttgtggtt tgtcagcatt cctaattgag atagaaagtc aaataatttc
     4561 ttgtttctcc ggctgtcatc aagatggttt agattaagac cgcgaacaat acaataccca
     4621 atactctgta ctgtattgtg aatttcttct atcaaactat tattgtttgc agataaaata
     4681 tacttttgat tcataacata ctcctgtcgt gaaatgccgt ctgaaacggt ttgcctgccc
     4741 ttacggcagc agccttgccc tgaacatcgc ctccttcatc tggcgcacgg cttcgggcag
     4801 tccgaggaag agggcttggg caatcagcga atgcccgatg ttcagttcgc ggatggcgag
     4861 gatttgggcg atgggggtaa cgttgtgtat ggtcagtccg tgtccggcgt tgacgactaa
     4921 gcccaaatcg ccggcgaaat gcgcgccgtt ttgcaggcgc tcgaattgct tgagttgttc
     4981 ggcgtgactg cgtgcatcgg catatgcgcc ggtgtgcagc tcgacaacgg gcgcgccgac
     5041 atcataggcg gcttggattt gcctgtcgtc ggcatcgata aacaaagaca cgcgtatgcc
     5101 cgcgtcggtc aggattttgg tgaattcggc gattttttcc tgttgcgcca atacgtccaa
     5161 accgccttcg gtcgtgattt cctgccgttt ttcaggcacg aggcacacat cttcaggcat
     5221 gacgttgagc gcgttttcca gcatttcttc cgtcagcgcc atttccaaat tcaggcgcgt
     5281 gcggatggcg tttttaacgg caaacacgtc cgcatcttta atatggcggc ggtcttcacg
     5341 caagtgcatg gtaatcaggt cggcaccgtg cgtttcggca accagtgccg cttccacagg
     5401 gctgggataa gtcgtgccgc gcgcgttgcg gacggtggcg atgtggtcga tgttgacacc
     5461 cagaagcata atgtttcctt ttctcttcgt ttttctgttt ggcggcatgg tgcgggcgca
     5521 gctacgcggt attgcggtcg aactgcctta tctgttccaa cacctgccgc gatttcagcc
     5581 cttcgggcaa caggtggcgg ataaaaagcc gtgtgatttt caatgcctgt tgcaggcttt
     5641 cggcggtgcg gaaactgcct tcgcgcaaat cgatcaggct ttgcccttcg acaattgcgc
     5701 cggcttcgtg cgaaagcgcg tctgcgtcct cgcatacggg catgaccgcc tcttcgggca
     5761 tcagccggta ggttttgtcc gccaaaatat cgccgcccgt gccgtcggcg tgcaaatcgg
     5821 gggcaacgcc caaggcattg agcagcttcc actcgaagcg gcgcaaatcg gcaatatggt
     5881 tggcttcacg gcacaccgcc tccatcactt ccgccaacgc gtcgtataac tcgggcaacg
     5941 gatcttcgcg gacggtcaac ttcagcatca actcgttcac atacaatccg ctgaacaaag
     6001 ccctaccctg cggctgcggc cacccgccta tccattcggc gcgatgtagg gtcttcaact
     6061 cttgcgaacc ataccaagac gcactcaccg gcacaaacgg caccaacacg ccgcgcaatt
     6121 cgctctgccg cttgcgcgcg cttcttgcca aaagtgccac acgcccgtaa cggcggctga
     6181 aggcttcgac ccgcaggctg ctttcgcgcc atggcgagga agccaacagg aagacgggtt
     6241 cgtggttgac tcggtgttcg gacatcatgc ctgaaatgcc gtctgaacgc tgccgccgct
     6301 acaaaacggc ggtcgggtac gaaccgatga ctttgacgaa cgaagcgcgt tcgcccaagc
     6361 gttccaatgc cgtctgaatc tgcgcgtccc ggcggtgtcc ttcgatgtcg atgaagaaca
     6421 ggtattccca caaaacggat ttgctcggac ggctctcaaa cttggtcatg gaaatacccg
     6481 actcggtcag cggttgcagc agcgaggcaa ccgcgcctgc ccggttgggc gcggaaacgg
     6541 ccagcgaagt cttgtcgctg ccgcttgcac cggtttcgtg atgtcccatc accaagaagc
     6601 gcgtggtgtt gttcggttcg tcttcgatgc actcggcaac catatcgagt ccgtagattt
     6661 ccgccgccgt gcgtccggcg atggcggcaa ccgtaccgtc gtccgattcg gcaaccagcc
     6721 ttgcggcttc ggcattgctg gacacggcaa tccgttcggc gttgggcagg tgtctgccca
     6781 accagtcgtt gcactgcgcc aacgcctgcg cgtgggaaaa gactttggca atgccttcgg
     6841 tgctgccgtt gtttttacgc aaaaggttgt ggtggatgcg caaaacgatt tcgccgcacg
     6901 cctgcaacgc ggtaacggca agcaggtcta acgtgcgacc gaccgagcct tcggtcgaat
     6961 tttccacggg ggcgaccaga taatccgcct gacgcgtttc aacctgcttg aagcagtcgt
     7021 ctatggtcgg acacgccatg gtgtgcgcgg cgtgtccgaa atgtttgatt gccgcctgct
     7081 gggtaaacgt gccctgcggc cccagatagg cgatggtcag cgggcgttcg acggcgaggc
     7141 actcgctcat cacttcccga aacaggcgtg ctaccgattc gtcgggcagc gggcctttgt
     7201 tcaaatcctg aatgcggcgc aacacggcga cttcgcgttc ggggcggtac actgcgcccg
     7261 tgcctttcag ctcgccgatg gcgtgggcgt gttgcgcacg ttcgttgagc aggcgcagga
     7321 tttcggcatc gatggtgtcg atggcgttgc ggtggggaag gaggagttcg tcgatagttt
     7381 gggacataat ttcgcctgaa cagtaattta tcgtgcattc taacatcaaa tgccgtctga
     7441 aacggtttca gacggcattt tccgttaaag gtattcgctt tgcccgtttt ctttccacgc
     7501 acgatgcgag cagagccaca gaagcgcaat gccgcaagag gtggacgcgg tcatcgttgc
     7561 cgccatcacg gttgccgaac cgtcgtgcaa gaaggtcgcc gccataccca cccccgcgcc
     7621 gattaaagat tggaatacac ccaatacggc gtttgcgctg ccgccctctt ctttgaaata
     7681 ggacataaaa cacgcctgcg tgtttgcacc gaccaagccc tgcgtaccga cggaaaacat
     7741 cacgcacgcg accagcagcc aaaacggggg caacccgaaa aacagcacgg cggcgagttg
     7801 ggacaggttg gcggcaaact ggacgacaat cccccacagc aggatgcttt gcggatgcac
     7861 gccggttttg agccgccacg cggtaacgcg gttgaaaaac atcatcgtga tgatgtttag
     7921 tgcaaacgcc caagcgtatt gatgaggcgt aacacggtag agctgctggt acacgaagga
     7981 agattcggtc agaaaggcga acatcgaacc gaagctgaat gcctgaaaaa acagataacc
     8041 catcgcggca cgggttttca atacgcgctt gaaccgcccc gccaccagcc cgaacacgtc
     8101 ccgtccgatt ttgccgccga cggcgggctt gggcaggaaa tactgtacca aaccgagcag
     8161 caccagcgaa tacgccgcca gaaaaacaaa aatcgcctgc cagccaccca agccctgcaa
     8221 caatgcgccg accatgggtg cgaccagcgg cacaaccatc aaaatgatgc cgataagggc
     8281 aaacatctgg gcggctttgc gtccggaata ataatcgcgc accattgcgc cgacgatgac
     8341 cacagtcatg cccgcaccga atgcctgcac gacgcgcagg ttgaggagct gttcggcact
     8401 cgaagcaaat acgatggcgg caacggcaag gcagtagacg gccagtccgg tcagcgcgac
     8461 gggtttgcgc cctttgatgt cggacaccga accgccgacc acctgtccga acgccgtgcc
     8521 gaacataaac aaactcaaac tctgttcgat gcggtgaaca tccgcgttca gcgattgcgc
     8581 catttcggga atcgcgggca ggtaggcatc gatggaaaac ggcatcagcg taaccagcat
     8641 cgccatcaaa accgccatca gtttttcgct catttcagga taatgggcag aaggcataaa
     8701 ttctcgtccg attcgcaaac aaaccgcccg gcggcggaaa acacaatacg cggaaacgga
     8761 aaattttaac acaccggcac aaacaggcgg caacaaaagc cccggcaaaa ccggacgaac
     8821 cggaacgata tagtggatta acaaaaacca gtacagcgtt gccttgcctt agctcaaaga
     8881 gaacgattct ctaaggtgct taagcaccaa gtgaatcggt tccgtactat ctgtactgtc
     8941 tgcggcttcg tcgtcttgtc ctgatttttg ttaatccact ataaaatccc gtcattcccg
     9001 cgcaggcggg aatccggaca tccaacgctg cagcaatttg tcggaaataa ccgaaactca
     9061 aaaaaccgga tgcccgcctg cgcgggaatg acgatgcaaa gatggtcgtt atttcggata
     9121 aatatccgtc ttttcgttcc ggatacccgc tttcgcagga atggagatgg aaagatttca
     9181 gcctattcgg caatcatcaa ataccgcttc ccaactttat ttttgatgcg acagccggcc
     9241 ggcaaccaag gtggcggcga tgacgacaaa cacgcccaag gcggacacgg gcgacaggtg
     9301 ttcgcccaaa atcaaaaccg ccagcagcac gccgacgacg ggttcgagcg aaatcaacag
     9361 tcccgaaacg ttggcaggaa cacggctcat ccccttgttc cacagccaat aggcgtacca
     9421 gccgcacccc aagcccaaat acagcagcga caataccatc ccgacgttcc agtccacggt
     9481 ataactttgc gccaaagcaa gcgaaaacgg caggcacatc aacgatgcgg cggcaatgga
     9541 aacagatgtg aatgccggtg cgccgatgcg tgcaatcagc ctttgcgtcg gacgcatagc
     9601 ggcacaaaag cccgcgcccg ccaacaacac cagcaggcag ccgaaccagc cgacttcgcc
     9661 gccctcttcc gcaccgcccg ccatcagcag cgcgacaccg gcaaatgccg ccgcgccgca
     9721 tatccagtgg taggcacgcg ctttgtcgtt gaagaaaaag tgtccgacaa acaccatcag
     9781 cagcggctcg agtccgacaa tgaccgatgc gctggcggcg gaagtgtatt tcaacccgac
     9841 aaactgaagc agcagggtca gcacatagtt gacgaacgac acaatcagca acggcttcca
     9901 ttcctcacgc ggaatcttgc cgacatgacg gcggcaggcg ggcagtgcag gcagcgcagc
     9961 aatcagcagg cgcacgccga ccatcaatgc gggatcgatg ccgccataga catatttggc
    10021 ggcaataaac gagctgctcc agataatcag ggcaaggatt tggtaaaaca tagtgagtga
    10081 taaagtcaga tggtcataca aaagtatagc ggattaacaa aaatcaggac aaggcgacga
    10141 agccgcagac agtacaaatc gtacggaacc gattcactcg gtgcttcagc accttagaga
    10201 atcgttctct ttgagctaag gcgaggcaac gccgtactgg tttttgttca tccactataa
    10261 cagcaacc
//
LOCUS       DAXIDM010000062        10244 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000062 DAXIDM010000000
VERSION     DAXIDM010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10244
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.062"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(95..169)
                     /locus_tag="ACFOAE_001370"
     tRNA            complement(95..169)
                     /locus_tag="ACFOAE_001370"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(134..136),aa:Glu,seq:ttc)
     gene            complement(187..263)
                     /locus_tag="ACFOAE_001371"
     tRNA            complement(187..263)
                     /locus_tag="ACFOAE_001371"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Arg,seq:acg)
     gene            complement(373..2046)
                     /gene="recN"
                     /locus_tag="ACFOAE_001372"
     CDS             complement(373..2046)
                     /gene="recN"
                     /locus_tag="ACFOAE_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFC6884840.1"
                     /translation="MLLTLSLRDFVIVENLNLDFQSGFTVLTGETGAGKSITLDAIGL
                     LLGDKADYSQVRSGAKEAQLSALFDISHLPTLKAELYEQGLLNDGEEELSIRRIIDAK
                     GKSRSFINNQAATLAQLKSVGSQLIDIHGQNAHHSLNQEAAQRELLDAFAGSRAQAET
                     VRQLYQNWANSKKALQEAQEQAENIALEQERLEWQFNELNQLDIKQGEWEALSQSHDS
                     LAHSAELLQAAEEVGSKIDGDNGIQRHIYQCQKLLANLQNIEPRFAESLNMLASIEAE
                     LGEISANMRDVAGRSDINPNELAAQEQRMGELMGMARKYRIEPEELPAKLAEIEERLQ
                     SLQAAADLDALEHNVAHNFAEYQEAAHILSAMRHQAAERLSGETTEHMQHLAMKGARF
                     DIVLLPSSPTAHGLEQVQFQVAANKGNPPRPLNKVASGGELARISLALQVVASQYTQV
                     PTLIFDEVDTGIGGGVAEMVGKALRSLGRKHQVLAVTHLPQVASCGENHWRVRKHSEG
                     EQTVSEISILDKIQRVEEVARMLGGEVITDTTRQHAAELLQLASKNSLF"
     gene            complement(2230..2832)
                     /locus_tag="ACFOAE_001373"
     CDS             complement(2230..2832)
                     /locus_tag="ACFOAE_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFC6884841.1"
                     /translation="MTDKISPDALIEAALLTQTEPLTEKSMRELCVPPLSQDKLIDVL
                     AQLKTRWQDRALQLVHTQEGWRFQIVQTAFERLGSLQEQRAPRYSRAVMETLAIIAYQ
                     QPVTRGDIEGIRGVAVSQNVMQTLQDRGWIEVIGHRDTLGKPALWATTATFLSDLRLD
                     GLEELPPLTELGELVLPDLMEMPPTDEEEPEAVPSDTLPN"
     gene            complement(2933..3874)
                     /gene="ylqF"
                     /locus_tag="ACFOAE_001374"
     CDS             complement(2933..3874)
                     /gene="ylqF"
                     /locus_tag="ACFOAE_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFC6884842.1"
                     /translation="MAIQWFPGHMNKAKKAIAERAKSVDMVIEMLDARMPASSENPLL
                     AQLSKGKPKLKILNKQDLADPERTKVWLGHYNSRPDTRAIALDSSETGAHGKITQACR
                     AMIPHRQGIDKPLRVLICGIPNVGKSTLINGMIGKKSAKTGNEPGITKAEQRLFLADD
                     FWLYDTPGMLWPKIIVEEGGYNLAAGGAVGRNALDEEEVALELLDYLRRHYLPMLQER
                     YQADKDPSSHWDENVWLEWIAKKRGAVLSGGRINYQKAAENILTDFREGKIGRITLET
                     PNQWETWLKKARQKEAELKAIREARKAERKGQKPSEA"
     gene            complement(3955..4809)
                     /gene="rapZ"
                     /locus_tag="ACFOAE_001375"
     CDS             complement(3955..4809)
                     /gene="rapZ"
                     /locus_tag="ACFOAE_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFC6884843.1"
                     /translation="MKIVLISGLSGSGKSVALRQMEDSGYFCVDNLPLEMLPALVSYH
                     IERADETELAVSVDVRSGIDIGQAREQIASLRGLGHRVEVLFVEAEESVLVRRFSETR
                     RGHPLSNQDMTLLESLKKEREWLFPLKEIAYCIDTSKMNAQQLRHAVRQWLKVERTGL
                     LVILESFGFKYGVPNNADFMFDMRSLPNPYYDPELRPYTGMDKPVWDYLDGQPLVQEM
                     VDDIERFVTHWLPRLEDESRSYVTVAIGCTGGQHRSVYIVEKLARRLKGRYELLIRHR
                     QAQNLSDR"
     gene            complement(4790..5752)
                     /gene="hprK"
                     /locus_tag="ACFOAE_001376"
     CDS             complement(4790..5752)
                     /gene="hprK"
                     /locus_tag="ACFOAE_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFC6884844.1"
                     /translation="MPSISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALV
                     GHLNFIHPNQIQVVGLAESEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLR
                     DYCHKNDIPLLTSKLESPYLMDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGL
                     GKSELALELISRGHSLIADDAVELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIF
                     GETSIRPKKILQLIINLVEADDEYMKQLDRLSIRTETESILNVNVRSVTLPVAVGRNL
                     AVLVEAAVRNYILQLRGKDSTREFLERHQTQLKENEQHNENRPD"
     gene            complement(5754..6203)
                     /gene="ptsN"
                     /locus_tag="ACFOAE_001377"
     CDS             complement(5754..6203)
                     /gene="ptsN"
                     /locus_tag="ACFOAE_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HFC6884845.1"
                     /translation="MSLIGEILPLSHIVLDMEVGSKKRLFEEAGLLLERESSLFHADV
                     FECLFAREKLGSTGLGQGVAIPHGRHAGVKQATGAFIRTREPVGFDAPDGKPVSLIFI
                     LLVPENATGEHLEVLSKLAGKFSQKSIRESLMTVSSAEEVRAILTEE"
     gene            complement(6388..7278)
                     /gene="ubiA"
                     /locus_tag="ACFOAE_001378"
     CDS             complement(6388..7278)
                     /gene="ubiA"
                     /locus_tag="ACFOAE_001378"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008412 - 4-hydroxybenzoate
                     octaprenyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HFC6884846.1"
                     /translation="MNPKSPLFLRLSDRLDVYLRLMRADKPIGTLLLLWPTYWALWLA
                     SDGIPDLAVLAAFTIGTFLMRSAGCVINDFADRDFDGAVERTKNRPFAQGRVKKKEAL
                     LLTAFLCLLAALCLIPLNHLTWLMSLPALFLALTYPFTKRFFPIPQLYLGLAFSFGIP
                     MAFAAVAGNVPPQAWILFAANVLWTLAYDTVYAMADKEDDLKIGIKTSAVTFGRYDIA
                     AVMLCHGGFTLLMAVLGVVIGAAWAYWTAIPIVLLLQYRQYAAIKSRVRQICFETFLA
                     NNRIGWVWFTAIFAHTFFAK"
     gene            complement(7308..7784)
                     /locus_tag="ACFOAE_001379"
     CDS             complement(7308..7784)
                     /locus_tag="ACFOAE_001379"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008813 - chorismate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HFC6884847.1"
                     /translation="MEHLFGKWLPDLPTPISDGISLPMVRLLHTRSLTAALRALPHTF
                     SVELLKLGELETECGGRLVREVLLKLDGIPVVAARSECRIGSAFWQNILDCGTRPLGE
                     RLFQADLEGARSAFEFAVSGEGCGRYFAARRSRFSRHGEEMLLTEYFLPELKRFIG"
     gene            complement(7799..8446)
                     /gene="bioD"
                     /locus_tag="ACFOAE_001380"
     CDS             complement(7799..8446)
                     /gene="bioD"
                     /locus_tag="ACFOAE_001380"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HFC6884848.1"
                     /translation="MKGVYFVSGIDTDIGKTIATGVLAKQLLQQGKSVITQKPVQTGC
                     QNIAEDIAAHRKIMGIPMQEADKQRLTMPEIFSYPASPHLAARLDGRALDLDKIRTAT
                     QELAAQYEVVLVEGAGGLMVPLTENLLTIDYIRQQGYPVILVTSGRLGSINHTLLSFA
                     ALKQYGIRLYSLVFNHIHDSRDAHIAQDSLNYLKCRLKADFSEAEWMELAKTDAV"
     gene            complement(8443..9744)
                     /gene="bioA"
                     /locus_tag="ACFOAE_001381"
     CDS             complement(8443..9744)
                     /gene="bioA"
                     /locus_tag="ACFOAE_001381"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HFC6884849.1"
                     /translation="MPSEHQHTSSLLDFDRTHLLHPYTSMTDPLPVYPVKRAEGVFIE
                     LADGTRLVDGMSSWWCAIHGYNHPVLNQAVETQIKQMSHVMFGGLTHEPAVELGKLLV
                     GILPQGLDRIFYADSGSVSVEVALKMAVQYQQARGLRAKQNMATVRRGYHGDTWNAMS
                     VCDPETGMHHIFGSALPQRYFVDNPTSRFDDEWDEADLQPVRALFEVHHADIAAFILE
                     PVVQGAGGMYFYHPQYLRGLRDLCDEFDIVLIFDEIATGFGRTGKMFACEHAEVVPDI
                     MCIGKGLSGGYMTLAAAITSQKVTETISRGEAGVFMHGPTFMANPLACAVACASVKLL
                     LSQDWQANIRRIESILKGRLKAAWDIRGVKDVRVLGAIGVIELDKGVDMARFQADCVA
                     QGIWVRPFGRLVYLMPPYIISDGVLTKLADKTVQILKEHSK"
     gene            complement(9958..10197)
                     /locus_tag="ACFOAE_001382"
     CDS             complement(9958..10197)
                     /locus_tag="ACFOAE_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884850.1"
                     /translation="MNVWDIWGRMVEIYHKYKKPCLVLAVDFVMGMVFIEPNEEPCIG
                     RCYAPMSESPDFANAVAMAVAMICIVWIAVLSMTD"
BASE COUNT         2373 a         2775 c         2608 g         2488 t
ORIGIN      
        1 tgagaaatga gaaatgagaa atgagaaatg agaaatgaga aatgagaaat gagaaatgag
       61 aaatgcctcc gatataatcg gaggcatttt gaattggcac gcccacgggg aatcgaaccc
      121 cggttaccgc cgtgaaaggg cgatgtccta accgctagac gatgggcgca tattgtattt
      181 tcttactggc gcacccggag cgattcgaac gcccgaccct ctggttcgta gccagatact
      241 ctatccaact gagctacggg tgcagcacaa tcacttgttc aagtgattaa gaaagcgtga
      301 taatacggat ttatctgagt tctgtctatt gttttagact tttattttta gttatttttt
      361 aactgattga ttttaaaata aactattttt cgacgcaagt tgcagcaatt ctgccgcatg
      421 ttgccgcgtc gtatcggtaa tgacttctcc gcccaacata cgggcaacct cttcgacccg
      481 ttggatttta tccaatatac tgatttcgct gacggtttgc tctccctcgc tgtgcttgcg
      541 cacccgccag tggttttcgc cgcaggatgc gacttgcgga agatgggtaa cggcaagcac
      601 ctgatgtttt ctgcccaacg aacgtaatgc cttgccgacc atttcagcca ctccccctcc
      661 aataccggta tcgacctcat caaaaatcag ggtgggaact tgggtatatt ggctggcaac
      721 aacctgtaag gcaaggctga tacgcgccaa ttcgccgccg gaggcaactt tattcagcgg
      781 acggggcgga ttgcctttgt tggcggcaac ttgaaattga acctgctcca aaccgtgtgc
      841 cgtcggcgac gagggcaaca ggacgatgtc gaaacgtgca cctttcatgg caaggtgttg
      901 catatgctcg gtcgtttcgc cgctcaaacg ctctgccgcc tgatggcgca tggcagaaag
      961 gatgtgggca gcttcctgat attcggcaaa attgtgggca acattatgct cgagcgcgtc
     1021 caaatcggcg gcagcttgca ggctttgcag gcgttcttcg atttctgcca acttggcagg
     1081 caactcttca ggctcgatcc ggtatttccg cgccatcccc atcagttcgc ccatacgctg
     1141 ttcctgtgcc gccaattcat tggggttgat gtcgctgcgt cctgccacat cgcgcatatt
     1201 ggcactgatt tcgcccaatt cggcttcgat gcttgccaac atattcaggc tctcggcaaa
     1261 gcgcggctcg atgttttgca gattggccaa tagtttttga cattgataga tatggcgttg
     1321 gatgccgttg tcgccgtcaa tcttgcttcc gacttcttcg gcagcctgca acagctcggc
     1381 agaatgggca aggctgtcgt ggctttggct gagagcttcc cattcgcctt gtttaatgtc
     1441 caactgattc aattcgttaa actgccattc cagacgctct tgttcgagtg caatgttttc
     1501 tgcctgttcc tgcgcttcct gcaatgcttt ttttgagttt gcccagtttt gataaagctg
     1561 cctgacggtt tccgcctgcg ccctgctgcc cgcaaatgcg tccaacaatt cgcgctgggc
     1621 ggcttcctga ttaagcgaat gatgggcgtt ttgcccgtgg atgtcgataa gctggctgcc
     1681 gacggatttg agttgcgcca aggtagcggc ctgattgttg ataaagctgc ggcttttgcc
     1741 tttggcatcg ataatgcggc ggatactgag ttcttcttct ccgtcgttta aaagcccctg
     1801 ttcatacaat tctgctttta aagtaggcaa atgggaaata tcgaacaatg ccgacaactg
     1861 cgcttctttt gcgccgctgc ggacttggct gtaatcggct ttatcgccca acagcagacc
     1921 aatcgcatcc aaagtaatgg acttgcccgc gccagtttct ccggtcaata cggtaaagcc
     1981 gctttgaaaa tccagattca gattttcaac aatgacaaaa tcacgcaaag aaagtgttag
     2041 aagcatcgtg aggattcctt agcaattcta ccgacaaaag caatatcaac tttagatata
     2101 cgaattataa ctaagatttt ttaaattaaa aataagtttt tccttaattt ttcttaatgc
     2161 ttgtttttat ctgcttattt gttgcaatgc cgtctgaagc aatgtgcgtt tcagacggca
     2221 tttggaattt cagttgggca gggtatcgga cggtacggct tccggctctt cttcatccgt
     2281 aggcggcatt tccattaaat cgggcaaaac cagttcgccc agttcggtca gcggaggaag
     2341 ttcttccaaa ccgtccaagc gcaaatcgct gaggaacgtt gccgttgttg cccacaatgc
     2401 gggttttccc aatgtgtccc gatgtccgat gacttcaatc cacccccgat cctgcaaggt
     2461 ctgcatcacg ttctgcgaca ccgccacgcc gcgtatgccc tcgatgtcgc cgcgcgttac
     2521 gggctgctgg taggcgataa tcgccagtgt ttccatcacg gcgcgggagt agcgcggcgc
     2581 acgctgttct tgcaggctgc ccagccgctc gaatgccgtc tgaacaatct gaaaacgcca
     2641 gccctcttgc gtatgcacca gttgcaacgc cctatcctgc caacgcgttt tcaactgcgc
     2701 caacacatca atcagtttgt cctgcgacag tggcggcaca cacaattcgc gcatagattt
     2761 ttcggtcagc ggttcggttt gggtcagcag tgcggcttca attagtgcgt cgggagaaat
     2821 tttgtcggtc atacgggtat ccgtgctgaa acggcatggg tttggatatg ccgtctgaaa
     2881 tcggttggag tagagagaag ctgcctgaaa aatatttttc agacggcatt ctttatgctt
     2941 ccgaaggctt ctgcccttta cgctctgctt ttctggcttc gcgtatggct ttgagttcgg
     3001 cttctttctg acgggctttt ttgagccaag tttcccattg gttcggcgtt tcgagggtga
     3061 ttctgccgat tttgccttca cggaagtcgg taaggatgtt ttcggcggct ttttggtagt
     3121 tgatccgtcc gccgctgagg actgcgccgc gttttttggc tatccattcg agccaaacgt
     3181 tttcgtccca gtggctgctg gggtctttgt cggcttggta gcgttcttgc aacataggga
     3241 ggtagtggcg gcggaggtag tctaaaagtt cgagggcgac ttcttcttcg tccaacgcgt
     3301 tgcgtccgac tgcgccgccg gcggcaaggt tgtagccgcc ttcttcgacg atgattttcg
     3361 gccacagcat tccgggggtg tcgtagagcc agaagtcatc ggcgaggaag aggcgttgtt
     3421 cggctttggt gatgccgggt tcgttgccgg ttttggcgga ttttttgcct atcatgccgt
     3481 tgatgagggt ggacttgcca acgttgggga tgccgcagat gaggacgcgc aggggtttat
     3541 ctatgccttg ccggtgggga atcatcgcgc ggcaggcttg ggtgattttg ccgtgtgcgc
     3601 cggtttcgga ggaatcgagg gcaatggcgc gcgtgtcggg gcggctgttg tagtggccaa
     3661 gccagacctt tgtgcgttcg gggtcggcaa gatcttgttt gtttaggatt ttaagtttgg
     3721 gtttgccttt ggaaagctgg gcaagcaggg ggttttcgct ggaggcgggc atacgcgcgt
     3781 ccagcatttc aatcaccata tcaacgcttt ttgcacgctc ggcgatggct tttttcgcct
     3841 tgttcatatg gccgggaaac cattggattg ccatgtctgt tctttctttt caatatttga
     3901 aatgccgtct gaaacggagg acggggtttc agacggcata atggtttgac ggaattagcg
     3961 gtctgacagg ttttgcgcct gtctgtgccg tatcagcaat tcataacgcc ctttcaacct
     4021 tcgggcgagt ttttcgacaa tatagaccga acggtgctgt cctcccgtgc aaccgatggc
     4081 gacggtaacg tagctcctgc tttcatcctc caaacgcggt aaccaatgcg taacaaacct
     4141 ttcgatgtcg tcaaccattt cctgcacaag cggctgtccg tccaaataat cccaaacggg
     4201 cttgtccata ccggtgtaag gcctcaactc gggatcgtaa tacgggttgg gcagactgcg
     4261 catatcgaac ataaaatccg cgttgttcgg cacaccgtat ttgaacccga aggactccaa
     4321 aatcaccagc agcccggtac gttcgacctt cagccactgc cggactgcat ggcggagctg
     4381 ttgggcattc atcttggaag tgtcgataca ataggcgatt tctttaagcg ggaacagcca
     4441 ttcccgttct ttctttaagc tttccaacaa ggtcatatcc tgattactca gagggtggcc
     4501 tcgcctggtt tcggaaaacc ggcggaccaa cacgctttct tccgcctcga caaacaaaac
     4561 ttcaaccctg tgccccagtc cgcgcagaga ggcaatctgt tcccgcgcct gtccgatgtc
     4621 tatgccggaa cgcacatcga cgctgaccgc caattcggtt tcgtccgcac gctcgatatg
     4681 atacgacacc agcgcgggca acatttccaa aggcaaattg tccacgcaga aataacccga
     4741 atcttccatt tggcgcagtg cgacggattt gcccgaaccg gacaacccgc taatcaggac
     4801 gattttcatt gtgttgctcg ttttctttaa gctgcgtctg atgacgttcc aaaaattcgc
     4861 gcgtactatc cttaccgcgc aactgaagaa tataattgcg taccgccgcc tcaaccaaaa
     4921 cggcgaggtt gcgtccgacg gcgacgggca gcgtaaccga acggacgttg acgttgagga
     4981 tggattcggt ttcggtgcgg atgctcaacc ggtcaagctg cttcatatac tcgtcgtccg
     5041 cctcgaccaa attgataatg agttgcagga tttttttggg gcggatggaa gtttcgccga
     5101 aaatatggcg gatattgagt atccccaagc cgcgcacttc caaaaaatcg cgcagcatag
     5161 gcgaacaacg cccttccaat gtttccggac cgatgcggaa cagctccacc gcatcgtcgg
     5221 caatcaggct gtgtccgcgc gaaatcagtt ccaatgccaa ttcgctcttg cccaaacccg
     5281 aatgcccggt aatcagcacg ccgatttcaa acacatcgag aaatacgccg tgtttgacgg
     5341 acgatgccgc cagggtgcgt tgcaggtaaa tccgcaacac gtccatcaga taggggcttt
     5401 cgagtttgga agtcagcagt ggaatatcgt ttttgtggca gtagtcgcgc agtcccgggg
     5461 aaaccggcaa gccgtttgcc acaataacca aagacataga aatgtcgaac aggtcgccaa
     5521 actgataacc cgtttccccc gattcgaggc ggttcagata ttccgactct gccaaaccga
     5581 ccacttggat ttggttggga tgaatgaaat tcaggtgtcc gactagggcg aggacgggct
     5641 tgtccgcctc tacgccgata cggttgtccg cacccgaatt gccggcggcc caagcgagtt
     5701 gcagtttgta ttggttgtca tcaaacaggc ggcggacgga gatactgggc atattattct
     5761 tcagtcagga tggcacggac ttcttccgca gaggaaaccg tcatcagcga ttctctgatg
     5821 cttttttggg aaaacttgcc ggccagtttg gataagactt ccaaatgctc gccggttgcg
     5881 ttttccggaa ccagcaagat aaaaatcagg gaaaccggct tgccgtccgg tgcgtcaaat
     5941 ccgacgggtt cgcgcgtgcg gatgaacgcg cccgtcgcct gcttcacgcc ggcatgacgg
     6001 ccgtgcggga tggcaacgcc ctgccccaaa ccggtcgaac cgagtttttc acgggcaaaa
     6061 agacattcga aaacatcagc atggaacaat gaggattcgc gttccaaaag caggcctgct
     6121 tcctcaaaca gccttttttt actgcctacc tccatatcca aaacaatatg ggacaaaggc
     6181 aaaatttcgc cgataaggct cataagcttc tcttttcaga catcgcaaaa cagaaagatt
     6241 gtaccgactg ctggggcaaa tctcaatccc gcatacggta cgggctgaca taacacagcg
     6301 ttttaaagac atattttaac gcttttcggc acagatagaa atgccgtcca aagcagttta
     6361 cggctcttca gacggcattg ccctgcctta tttcgcgaaa aacgtatggg caaaaatggc
     6421 ggtaaaccac acccaaccaa ttctgttgtt tgccaaaaac gtttcaaaac agatttgccg
     6481 gacgcggctt ttgatggcgg catattggcg gtattgcagc agcaggacga tggggattgc
     6541 cgtccaatat gcccatgccg caccgataac cacccccaat actgccatca gcagggtaaa
     6601 gccgccatga cacagcataa cggcggcgat gtcgtaacgc ccgaacgtga cggcggaggt
     6661 tttgatgccg attttcaaat cgtcttcttt gtccgccatt gcataaaccg tgtcatacgc
     6721 cagagtccat aacacattgg cggcaaagag tatccacgct tgaggcggca cgtttccggc
     6781 aacggcggca aacgccatcg ggataccgaa ggaaaaggca agcccgagat agagttgggg
     6841 aatcggaaaa aaacgtttgg taaacgggta agtcagcgca agaaacagcg cgggcaggct
     6901 catcagccat gtcagatgat tcagcggaat caggcacaat gcggcaagca ggcacaaaaa
     6961 tgccgtcagc agcagcgctt cttttttctt gacccggccc tgtgcgaacg gacggttttt
     7021 agtgcgctcg acagccccgt caaaatcgcg gtcggcaaaa tcgttgatga cgcaaccggc
     7081 actgcgcatt aaaaacgtac cgattgtaaa cgccgccaat accgccaaat cgggaatgcc
     7141 gtctgaagcc agccacaatg cccagtaggt cggccacagc aaaagcagcg tcccaatggg
     7201 cttgtccgcc cgcatcaggc gcaggtacac atccaaacgg tcggacagtc gtaaaaataa
     7261 aggggattta ggattcatat tgccgcacag cttgaaaaaa cggtatttta tccgataaag
     7321 cgtttcagtt cgggcagaaa atactcggtc agcagcattt cctcgccgtg acgggaaaac
     7381 cgagaacgcc gcgcggcaaa gtaccgtccg catccttcgc cggaaacggc aaactcaaac
     7441 gccgaacgcg ccccttccaa atcggcttga aacagacgct cgcccaaagg gcgcgtgccg
     7501 cagtccaaaa tgttttgcca aaacgccgaa cctatacggc actcgctcct tgccgcgaca
     7561 acagggatac cgtccagctt caacaaaact tcgcgcacca gcctccctcc gcattccgtc
     7621 tccaattcgc ccagtttcag cagttccacc gaaaatgtat gcggcaaggc gcgcaatgcg
     7681 gcggtcagcg accgggtgtg cagcagccgc accatcggca ggctgatgcc gtctgaaatg
     7741 ggggtgggca agtcgggcag ccatttccca aataggtgtt ccatattttt cccaatcttt
     7801 ataccgcgtc tgtttttgcc aactccatcc attccgcttc ggaaaaatcg gctttcagac
     7861 ggcatttcaa gtagttcagg ctgtcttggg cgatgtgtgc gtcgcggctg tcgtggatgt
     7921 ggttgaacac gaggctgtac aagcgaatgc cgtattgttt gagcgctgcg aaactgagta
     7981 aagtgtggtt gatactgcca agccgtccgc tggtaacgag gatgacggga tagccttgct
     8041 gacggatata atcaatggtt aacaggtttt ccgtcagcgg aaccatcaat ccgcccgcgc
     8101 cttcgaccaa aacgacttcg tactgcgccg ccaattcttg tgtggcggtg cggattttgt
     8161 ccaagtccaa agccctgccg tcaagacggg cggcaaggtg gggcgaagcg ggatagctga
     8221 agatttcagg catagtcagc cgctgtttgt ccgcttcctg catcgggatg cccatgattt
     8281 tgcggtgggc ggcgatgtct tcggcgatgt tttgacatcc ggtttgcacg ggtttttgcg
     8341 tgattacgct tttgccttgc tgcaacaatt gttttgccaa cacgccggtg gcgatggttt
     8401 tgccgatgtc cgtgtctatg ccgctgacga agtaaacgcc tttcatttgc tgtgttcctt
     8461 caagatttgt acggttttgt cggcaagttt ggtcaaaacg ccgtctgaaa taatatacgg
     8521 cggcatcaga tacaccagcc tgccgaacgg gcgcacccaa atgccctgcg ccacgcaatc
     8581 tgcttgaaaa cgcgccatat ccacgccttt atccagctcg atcacgccga tggcacccaa
     8641 aacgcgtacg tctttcacgc cgcgaatgtc ccacgcggct ttcagacggc cttttaagat
     8701 gctttcaatg cggcggatat ttgcctgcca gtcttgagac aaaagcagtt tgaccgaagc
     8761 gcaggcaacg gcacacgcca gcgggtttgc cataaacgtc gggccgtgca taaacacgcc
     8821 cgcttcgccg cgcgaaatcg tttcggtaac tttttgcgaa gtgattgctg ccgccagcgt
     8881 catatagccg ccgctcaaac ccttgccgat gcacataata tccggcacga cctccgcgtg
     8941 ttcgcaggca aacatcttgc ccgtgcgccc gaatccggtg gcgatttcat caaaaatcaa
     9001 cacgatgtca aattcgtcgc acaaatcgcg caatccgcga agatactgcg gatgataaaa
     9061 atacatgccg cccgcgccct gcacgaccgg ctctaaaata aaggcggcaa tatccgcatg
     9121 atgcacttca aacaaggcgc ggacaggctg caaatccgcc tcgtcccatt catcgtcgaa
     9181 acggcttgtc gggttatcga caaaataacg ctgcggcaac gcgctgccga aaatatggtg
     9241 catccccgtt tccggatcgc agacggacat cgcgttccaa gtatcgccgt gatacccgcg
     9301 ccgcaccgtc gccatatttt gttttgcacg caaaccccgc gcctgctgat attgcaccgc
     9361 cattttcaac gcgacttcta ccgaaaccga gcctgaatcc gcataaaaaa tacggtccag
     9421 cccttgcggc aaaattccga ccaataattt gcccagttcc accgccggct catgcgtcaa
     9481 accgccgaac atcacatgcg acatttgttt aatctgcgtc tcaaccgcct gattcaaaac
     9541 aggatgattg taaccgtgta tcgcacacca ccaggacgac atcccgtcaa ccagccgcgt
     9601 gccgtccgcc aattcgataa acaccccttc tgcacgtttg acaggataaa cgggaagcgg
     9661 atcggtcatg gaagtatagg gatggagcag atgggtacgg tcgaaatcaa gtaatgatga
     9721 tgtgtgttga tgttcagacg gcataagttt ctctcttttc ttattgctgc attcaaacgc
     9781 aaacgcgtat tctactccga cagaccgttt cccacacctc tccatccgtt tcgggcgcaa
     9841 aaccgcgaaa caaatcgttc cgcaacataa gcgcacaccg tttcgcattc ctcaagcccg
     9901 attggaatca gacggcccaa cgcccaatac cgtttcacgc agcctccgcc caacgcttca
     9961 atcagtcata gacaaaacgg caatccatac gatacagatc atagcaacag ccatcgcaac
    10021 agcgttggca aaatcagggg actccgacat aggcgcatag catctgccga tgcacggctc
    10081 ctcattcggc tctatgaata ccatacccat cacaaaatcc accgccaaaa ccaggcacgg
    10141 cttcttatac ttatgataga tttccaccat cctgccccat atatcccaaa cattcatacc
    10201 gcatatcccg caggcaacaa attccgattg aaggttacag ccct
//
LOCUS       DAXIDM010000063        10235 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000063 DAXIDM010000000
VERSION     DAXIDM010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10235
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.063"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(257..1474)
                     /locus_tag="ACFOAE_001383"
     CDS             complement(257..1474)
                     /locus_tag="ACFOAE_001383"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFC6884851.1"
                     /translation="MALIVHKYGGTSVGSPERIKNVAKRVAKARAEGHDIVVVVSAMS
                     GETNRLVALAHEMQEHPDPRELDVVLSTGEQVTIGLLAMALKDIGVDAKSYTGWQVAL
                     KTDTAHTKARIESIDDEKMRADLTAGKVVIVAGFQGISSEGDISTLGRGGSDTSAVAL
                     AAALKADECQIYTDVDGVYTTDPRVVPEARRMDTVTFEEMIELASLGSKVLQIRSVEF
                     AGKYKVRLRVLSSLQDGGNGTLITFEEDDNMERAAVTGIAFDKNQARINVRGVPDKPG
                     VAYQILGAVADANIEVDMIIQNVGSEGTTDFSFTVPRGDYKQTLEILSERQDSIGAAS
                     IDGDDTVCKVSAVGLGMRSHVGVAAKIFRTLAEEGINIQMISTSEIKVSVLIDEKYME
                     LATRVLHKAFNLG"
     gene            complement(1676..2404)
                     /gene="rph"
                     /locus_tag="ACFOAE_001384"
     CDS             complement(1676..2404)
                     /gene="rph"
                     /locus_tag="ACFOAE_001384"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFC6884852.1"
                     /translation="MPDYIRISRAADSLRDIKITPHFLPHTDGSCLIECGNTKVICTA
                     SIDENVPPFLRGKNQGWVTAEYGMLPASTASRMRREASAGKQSGRTQEIQRLIGRSLR
                     AVVDMEKLGERQILIDCDVIQADGGTRTASITGAFVALQIAVGKLVSDGILSENPIRE
                     AVAAVSVGVVNGVPLLDLDYPEDSGCDSDVNIVMTASGKIIEIQGTAEDAPFSLDELG
                     KLVALAQKGIGELLQHQQNALSAA"
     gene            complement(2486..2950)
                     /locus_tag="ACFOAE_001385"
     CDS             complement(2486..2950)
                     /locus_tag="ACFOAE_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFC6884853.1"
                     /translation="MYKHLVVAVDGSETSINALKHAAELAGVNGARLTLVHVANPAEY
                     MALAPEFLQHESYEAAAVAQGNEVLDAAERTARELGVENTVKHLLVANKGAREMAQDL
                     VDYADENGADLLVLGTHGRTGLMHLLMGSFAETVMRQSHLPLLIIRSKAEEA"
     gene            3167..3943
                     /locus_tag="ACFOAE_001386"
     CDS             3167..3943
                     /locus_tag="ACFOAE_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HFC6884854.1"
                     /translation="MSDNALTSSRRFGGIARLYGDSALAHFSQAHVCVVGVGGVGSWA
                     VEALARTGIGRLTLIDLDNVAESNVNRQLHALTGDFGKAKVTALRERVAQINPGCQVF
                     EIEDFVTEDNLPEYFGKGFDFVIDAIDQVRVKAAMAAYFVERKQPFVLSGGAGGQKNP
                     ALIQTADLSRVTHDPLLANLRYTLRKRYGFSRDTKANMRVPCVYSTENIVPPQSREAC
                     SADAAPQGLSCAGYGASMLVTASFGLYCAQAAVEHIADKK"
     gene            4188..5042
                     /locus_tag="ACFOAE_001387"
     CDS             4188..5042
                     /locus_tag="ACFOAE_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ScpA family protein"
                     /protein_id="HFC6884855.1"
                     /translation="MPPIPAPSAPSEHTVAWVFGQPVTDLPQDLFIPPDALKVVLGSF
                     QGPLDLLLYLIRKQNIDVLDIPMVKITEQYLHYIAQIEAYQFDLAAEYLLMAAMLIEI
                     KSRLLLPRTETVEDEEADPRAELVRRLLAYEQMKLAAQGLDALPRAGRDFAWAYLPLE
                     IAVEAKLPEVYITDLTQAWLGILSRAKHTRSHEVIKETISVRAQMTAILRRLNGHGIC
                     RFHDLFNPEQGAAYVVVNFIALLELAKEGLVGIVQEVGFGEIRISLNHEGAHSDGISG
                     TRGGRDVF"
     gene            5083..6291
                     /gene="pncB"
                     /locus_tag="ACFOAE_001388"
     CDS             5083..6291
                     /gene="pncB"
                     /locus_tag="ACFOAE_001388"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFC6884856.1"
                     /translation="MTGIIHSLLDTDLYKFTMLQVVLHQFPQTHSLYEFRCRNASTVY
                     PLADIREDLEAELDALCQLRFTHDELDYLRSLRFIKSDFVDYLELFQLQRRFVEIGTD
                     DKDRLNIRIEGPMIQAMFFEIFILAIVNELYFRRLETPAVIEEGERRLQAKAARLKEI
                     AAAQNPDEPPFLISDFGTRRRYKLAWQEHVIRTLLEAAPSIVRGTSNVFLAKKLGITP
                     IGTMAHEFLQAFQALDVRLRNFQKAALESWVHEYRGDLGVALTDVVGMDAFLRDFDLY
                     FAKLFDGLRHDSGDPYVWGDKAYAHYQKLKIDSRTKMLTFSDGLDIERSWALHQYFKD
                     RFKTGFGIGTNLTNDMGHTPLNIVLKLVECNGQSVAKLSDSPGKTMTNNSTFLAYLRQ
                     VFDVPEPETP"
     gene            6383..8101
                     /gene="argS"
                     /locus_tag="ACFOAE_001389"
     CDS             6383..8101
                     /gene="argS"
                     /locus_tag="ACFOAE_001389"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFC6884857.1"
                     /translation="MNLHQTVEHEAAAAFAATGIAGSPVVLQPTKNAEHGDFQINGVM
                     GAAKKAKQNPRELAQKVADALAGNAVIESAEVAGPGFINLRLRPEFLARNIQTALNDA
                     RFGVAKTDKPQTVVIDYSSPNLAKEMHVGHLRSSIIGDSISRVSEFMGNTVIRQNHVG
                     DWGTQFGMLVAYLVEQQKDNAAFELADLEQFYRAAKVRFDEDPAFADTAREYVVKLQG
                     GDETVLALWKQFVDISLSHAQAVYDTLGLKLRPEDVAGESKYNDDLQPVVDDLVQKGL
                     AVEDDSAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTDLACLRYRVGTLHADRLLY
                     VVDHRQALHFEQLFTTSRKAGYLPENVGAAFVGFGTMMGKDGKPFKTRSGDTVKLVDL
                     LTEAVERATALVKEKNPELGADEAAKIGKTVGIGAVKYADLSKNRTSDYVFDWDAMLS
                     FEGNTAPYLQYAYTRVQSVFRKAGEWDANAPTVLTEPLEKQLAAELLKFEDVLQSVAD
                     TAYPHYLAAYLYQIATLFSRFYEACPILKAEGASRNSRLQLAKLTGDTLKQGLDLLGI
                     DVLDVM"
     gene            8648..10066
                     /locus_tag="ACFOAE_001390"
     CDS             8648..10066
                     /locus_tag="ACFOAE_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HFC6884858.1"
                     /translation="MNIHTLLSKQWTLPPFLPKRLLLSLLILLAPNAVFWVLALLTAT
                     ARPIVNLDYLPAALLIALPWRFVKIAGVLAFWLAVLFDGLMMVIQLFPFMDLIGAINL
                     VPFILTAPTPYQIMTGLLLLYMLAMPFVLQKAAAKTDFRHIAVCAAVVAAAGYFTGHL
                     SYYDRGPMANIFGANNFYYAKSQAMLYTVSQNADFITAGLVDPVFLPLGNQQRAATHL
                     NEPKSQKILFIVAESWGLPANPELQNATFAKLLAQKDRFSVWESGSFPFIGATVEGEM
                     RELCAYGGLRGFALRRAPDEKFARCLPNRLKQEGYATFAMHGAGSSLYDRFSWYPRAG
                     FQEIKTAENLIGKKTCAIFGGVCDSELFGEVSAFFKKHDKGLFYWMTLTSHADYPESD
                     IFNHRLKCTEYGLPAETDLCRNFSLHTQFFDQLADLIQRPEMKGVEVIIVGDHPPPVG
                     NLNETFRYLKQGHVAWLHFKIK"
BASE COUNT         2350 a         3015 c         2578 g         2292 t
ORIGIN      
        1 cagtacggcg ttgcctcgcc ttagctcaaa gagaacgatt ctctaaggtg ctgaagcacc
       61 aagtgaatca gttccgtact atttgtactg tctgcggctt cgtcgccttg tcctgatttt
      121 tgttaatcca ctataaattt aatccactat attttttgtt ccaaagtcaa aatatgccgt
      181 ccgaacattc gggcggcaga caaaacggca ctgcccgata aaggcagtgc cgttgtccgt
      241 ttcaaaccgt gaaacatcag cccaaattaa aggctttatg caataccctg gttgccagtt
      301 ccatgtattt ttcatcaatc aatacggaaa ctttgatttc ggaggtggaa atcatttgga
      361 tgttgatacc ctcttcggcg agcgtgcgga agattttggc ggctacaccg acgtgcgaac
      421 gcatacccaa accgactgcg gagactttgc acacggtgtc gtcgccgtcg atagaagccg
      481 cgccgatact gtcttgacgt tccgacagga tttccaaagt ctgcttgtaa tcgccgcgcg
      541 gtacggtaaa ggaaaaatcg gttgtgcctt cgctgccgac attttggata atcatatcga
      601 cttcgatgtt ggcatcggca accgcgccta aaatctgata ggcgacgccg ggtttgtcgg
      661 gtacgccgcg cacgttgatg cgggcttggt ttttgtcgaa tgcgataccg gttacggcag
      721 ctctttccat attgtcgtcc tcttcaaagg taattaaggt gccgttgccg ccgtcttgca
      781 ggctgctcag tacgcgcagg cgcactttgt attttccggc aaattctact gaacggattt
      841 gcaaaacttt cgagccaagg ctggccagct caatcatttc ttcaaatgta accgtatcca
      901 tgcggcgcgc ttcgggtacg acgcgcggat cggtggtgta cacgccgtcc acgtcggtat
      961 agatttggca ttcgtccgct ttgagggctg cggcaagcgc aacggcggaa gtgtcggaac
     1021 cgccgcgtcc gagcgtggaa atatcgcctt cactgctgat gccttggaag ccggcaacga
     1081 tgacgacttt gccggcggta aggtcggcac gcattttttc gtcatcaatg ctttcgatgc
     1141 gggctttggt gtgggcggta tcggttttga gggcgacctg ccagcctgtg tagcttttgg
     1201 catccacgcc gatgtctttc aatgccatcg ccaaaaggcc gatggttact tgttcgccgg
     1261 tggacaaaac cacgtccaat tcgcgcggat cgggatgctc ctgcatttcg tgcgccaacg
     1321 cgaccaggcg gttggtttca ccgctcatgg cggatacgac gacgacaatg tcgtgtcctt
     1381 cggcgcgggc tttggcgaca cgtttggcca cgtttttaat gcgttcgggc gagcctacgg
     1441 atgtgccgcc gtatttgtgt acgattaacg ccatgtttcg tgctttcttg tgtgggattg
     1501 gtcgggcagc atggtttgct ggaaaagcgg ctattattac tattttttac atgaagttca
     1561 agaacggact gcgctttccc gcctgccgtt tgacagcggt cagcgaaaaa cctgttcttt
     1621 cagattgttg acaaaatgcc gtctgaacgg ttttcagacg gcatccggac gacaatcagg
     1681 cggcggacaa cgcattttgc tggtgttgca gcagttcgcc tatgcctttt tgcgccagtg
     1741 caaccagttt gcccaattcg tccaaactga acggcgcgtc ttccgccgta ccttggattt
     1801 cgatgatttt tcccgatgcg gtcatgacga tattcacatc actgtcgcaa ccggagtctt
     1861 cgggataatc caaatccaaa agcggcacgc cgttcactac gcctactgac acagcggcaa
     1921 cggcttcgcg gatggggttt tcactcaaaa tgccgtctga aaccagtttg ccgacggcga
     1981 tttgcagcgc gacaaacgca ccggtaatcg aagccgtgcg cgtaccgcca tctgcctgaa
     2041 tcacatcgca gtcaatcaag atttgtcgtt cgccgagttt ttccatatct acgaccgcgc
     2101 gtagcgaacg cccgataagg cgttggattt cttgtgtgcg cccggactgt ttgcccgccg
     2161 aagcttcgcg gcgcatacgc gaagcggttg aggcgggcag catcccgtat tctgcggtta
     2221 cccagccttg gtttttaccg cgcagaaacg gcgggacgtt ttcatctatg gaagcggtac
     2281 aaatcacttt ggtattgccg cattcaataa ggcacgaacc gtccgtatgc ggcaggaaat
     2341 gaggggtgat tttgatatcg cgcaggctgt cggcggcgcg cgagatgcgg atgtaatcag
     2401 gcatactgcc ctcccgttaa aaacagataa attaaaaagc cttaaatatg aaaaatcaca
     2461 tttaaggcct tcaaactgaa aatttctacg cctcttcggc tttgctgcgg ataatcaaaa
     2521 gcggcaggtg gctttggcgc attaccgttt cggcgaaact gcccatcaaa aggtgcatca
     2581 gaccggtgcg cccgtgcgtg cccaacacca gcaggtcggc accgttttca tcggcataat
     2641 cgaccaaatc ctgcgccatt tcacgcgcac ccttattggc aaccagcagg tgtttgacgg
     2701 tattttccac acccagttcc cgggcggtgc gctcggcggc atccaaaact tcgttgcctt
     2761 gcgcgacggc ggcggcttcg tagctttcgt gttgcaaaaa ttcgggggcg agcgccatat
     2821 attcggcagg attggcaacg tgtaccaaag tcagacgcgc accgttgacc ccggcaagct
     2881 cggcggcatg tttcagggca ttgatggacg tttcactgcc gtcaacggca acaaccagat
     2941 gtttgtacat atcgtattct ccttttgcac cgcctcgcgg tgccctcttg tcggatgggc
     3001 gcagggacag tttgcgccgt ttcattatag acccgctgtc gggctttata caacagccga
     3061 acagcccgac cgctttccag tataatatgc cgcttccgtg cagtcaggca ttttttgccg
     3121 gctttcgttc actttttgat ttgacgcaat cttgcaggat tcgaccatgt ccgacaacgc
     3181 tttgacctct tcgcgacgct tcggcggcat cgccagactc tacggagact ctgccttggc
     3241 gcacttttca caggcacacg tctgcgtagt cggcgtgggc ggtgtcggct cgtgggcggt
     3301 cgaggctttg gcgcggacgg gcatcggacg tttgactttg attgatttgg acaacgttgc
     3361 cgaatcgaat gtcaaccgcc agctgcacgc cctgaccggc gacttcggca aagcaaaagt
     3421 taccgccttg cgcgaacgcg tcgcccaaat caacccagga tgccaagtgt ttgaaattga
     3481 agatttcgtt accgaagaca atttgccgga atacttcgga aaaggttttg atttcgtcat
     3541 cgacgcgatc gaccaagtgc gcgtcaaagc agcaatggcg gcttattttg tggaacgcaa
     3601 acaaccgttt gtcctcagcg gcggcgcggg cggacaaaaa aatccggcgt taatccaaac
     3661 cgccgatttg agccgcgtaa cccacgaccc gctgcttgcc aacctgcgct acaccttgcg
     3721 gaaacgctac ggattcagcc gcgatacgaa agcaaatatg cgcgtgcctt gcgtgtattc
     3781 gaccgaaaat atcgtgccgc cgcagtctag ggaggcttgt tcggcagatg ccgctccgca
     3841 aggcttgtcg tgcgccggct acggtgcaag catgctcgtt accgcttcgt tcgggctata
     3901 ttgcgcacag gcggcggtgg aacacatcgc agacaaaaaa taagcaatgc cgtctgaaac
     3961 aggattcaga cggcatttga acaaacgcgg caatcaagct gtcggttcag aaaaaccaac
     4021 atcggcacgc ctaaaaccgt attcacaacc tgctcctttt caaaacattt gcatttaaaa
     4081 gccgttataa tgccgtctga acatctgccc gaccacatta tgcgtgaatg tcggcagatt
     4141 gttttctttt gtaaacttat attaaaatcc acttaccgat tcacgccatg ccgcccatcc
     4201 ctgccccatc cgcaccatcc gagcacactg tcgcatgggt attcggccaa cccgttaccg
     4261 atttgccgca ggatttgttt atcccgcccg acgcgctgaa agtcgtattg ggcagttttc
     4321 aaggcccttt ggatttgctg ctctacctta tccgcaagca gaacatcgat gttctcgata
     4381 ttccgatggt gaagattacc gagcagtatc tgcactacat cgcccaaata gaagcctatc
     4441 agtttgattt ggcggcggaa tacctgctta tggcggccat gctgattgaa atcaaatcgc
     4501 gcctgctgct gccgcgtacc gaaaccgtcg aagacgaaga agccgacccg cgtgccgagt
     4561 tggtgcgccg cctgctggct tacgaacaga tgaagctggc ggcgcagggt ttggacgcgc
     4621 tgccccgagc cggacgggat ttcgcgtggg cttacctgcc gctggaaatt gccgtcgaag
     4681 ccaagctgcc cgaagtctat attaccgact tgacgcaagc gtggctgggt attttgtctc
     4741 gggcaaaaca cacgcgcagc cacgaagtaa tcaaagaaac catctccgtg cgcgcgcaaa
     4801 tgacggcaat cctgcgccgt ttgaacggac acgggatatg caggtttcac gacctgttca
     4861 atcccgaaca gggcgcggct tacgtggtcg tcaacttcat cgcactgttg gagcttgcca
     4921 aagaaggttt ggtcggaatc gtacaggaag tcggtttcgg agaaatccga atcagcctca
     4981 atcatgaggg ggcacattca gacggcattt ccggcacacg gggcgggcgc gatgtgttct
     5041 aatacgcccc aagccgccac caaaaatcgg gagacacgcc atatgaccgg catcatacat
     5101 tcgctgcttg acaccgacct ctacaaattc actatgctgc aagtggttct gcaccagttt
     5161 ccgcagacgc acagccttta cgaattccgc tgccgcaacg cctcgaccgt ctatccgctt
     5221 gccgacatca gggaagactt ggaagccgaa ctcgacgcgc tctgccaact acgcttcacc
     5281 cacgacgaac tcgactacct ccgtagcctg cgtttcatta aaagcgactt tgtcgattat
     5341 ctcgaactct tccagctcca acgccgcttt gtcgaaatcg gcacagacga taaagaccgt
     5401 ctgaacatcc gcatcgaagg tccgatgata caggcgatgt tttttgaaat cttcatcctc
     5461 gccattgtca acgaacttta cttccgccgc ctggaaaccc ctgccgttat cgaagaaggt
     5521 gaacgccggc ttcaagccaa agccgcgcgc ctcaaagaaa tcgccgccgc acaaaacccc
     5581 gacgaaccgc ccttcctgat ttccgacttc ggcacgcgcc gccgctacaa gctcgcgtgg
     5641 caggaacacg tcatccgcac cctgctcgaa gccgccccaa gcatcgtgcg cggcaccagc
     5701 aatgtctttc tcgccaaaaa actcggcatc acccccatcg gcaccatggc gcacgagttc
     5761 ctccaagcct tccaggccct cgacgtacgc ctgcggaatt tccaaaaggc cgcgctcgaa
     5821 agctgggtgc acgaataccg gggcgatttg ggcgttgccc tgaccgacgt ggtcggtatg
     5881 gatgccttcc tgcgcgattt cgacctctat ttcgccaaac ttttcgacgg gctgcgccac
     5941 gacagcggcg acccttacgt ttggggcgac aaagcctacg cccactatca aaagctcaaa
     6001 atcgacagcc gcaccaaaat gctgaccttc tccgacgggc tggacatcga acgctcttgg
     6061 gcattacacc aatatttcaa agaccgcttc aaaaccggct tcggcatcgg caccaacctg
     6121 accaacgata tggggcatac gcctttgaat atcgtcttga aactggtcga atgcaacggg
     6181 cagtccgtcg ccaagctgtc cgactctccg ggcaaaacca tgaccaacaa cagcaccttc
     6241 ctcgcctacc tgcgccaagt gttcgacgta cccgaacccg aaacgccgta aaccggcaga
     6301 aaaagcacac aattcctgtt tctgccgcat aaaatctttt aaaataccgc ctgatttgaa
     6361 tttaaccgaa agaccgaact tcatgaacct acatcaaacc gtcgaacacg aagccgccgc
     6421 cgcctttgcc gccacaggca tcgccggcag ccccgttgtc ttgcagccga ccaaaaatgc
     6481 cgaacacggc gatttccaaa tcaacggcgt gatgggtgcg gcgaaaaaag ccaaacaaaa
     6541 cccgcgcgaa ctggcgcaaa aggtcgccga cgcattggca ggcaacgccg tcatcgaaag
     6601 cgcggaagtc gccggtcctg gttttatcaa cctgcgcctg cgccccgaat tcctcgcccg
     6661 aaacattcag acggccttga acgacgcgcg tttcggcgtg gcaaaaaccg acaaaccgca
     6721 aaccgtcgtt atcgactatt cctcgcccaa tctggcaaaa gaaatgcacg tcggccacct
     6781 gcgttccagc attatcggcg acagcatttc gcgcgtgtca gaatttatgg gcaataccgt
     6841 tatccgtcaa aaccacgtcg gcgactgggg tacgcagttt ggcatgttgg tcgcttattt
     6901 ggtcgagcag caaaaagaca atgccgcatt cgagctggcg gatttggagc agttttaccg
     6961 cgccgccaaa gtgcgctttg acgaagaccc cgcctttgcc gacaccgcgc gcgaatacgt
     7021 tgtgaagctg caaggcggcg atgaaaccgt tttggcattg tggaaacagt ttgttgatat
     7081 ttcgctctcg cacgcccaag ccgtttatga cacgctgggc ttgaaactgc gccccgaaga
     7141 tgtggcgggc gaatcgaaat acaacgacga tttgcagcct gtggtcgatg atttggttca
     7201 aaaaggtctg gcggtcgaag acgacagcgc gaaagtcgtg ttcttggacg agtttaaaaa
     7261 caaagaaggc gaacccgccg catttatcgt acaaaaacaa ggcggcggct tcctttacgc
     7321 ctccaccgat ttggcgtgtc tgcgctaccg cgtcggcacg cttcatgccg accgcctgct
     7381 gtacgtcgtc gaccaccgtc aagccctgca ctttgagcaa ctctttacca cttcccgcaa
     7441 agcaggctat ctgccggaaa acgtcggcgc agcatttgtc ggcttcggca cgatgatggg
     7501 caaagacggc aaaccgttca aaacacgcag cggcgacact gtaaaactgg tcgatctgct
     7561 gaccgaagcc gtcgaacgcg ccaccgcttt ggtgaaagag aaaaatcccg aattgggcgc
     7621 ggacgaagcc gccaaaatcg gcaaaaccgt cggcatcggc gcggtcaaat acgccgactt
     7681 gagcaaaaac cgcaccagcg attatgtgtt cgactgggac gccatgctct cgtttgaagg
     7741 caacaccgcc ccctatctgc aatacgccta cacccgcgtg caaagcgtgt tccgcaaagc
     7801 aggcgaatgg gatgcaaatg cgccaaccgt tttgaccgaa ccgctggaaa aacagcttgc
     7861 cgccgagctg ctgaaatttg aagacgtact gcaaagcgtg gcggacacgg cgtatccgca
     7921 ctacctcgcc gcctacctct atcaaattgc gaccctgttc agccgcttct acgaagcctg
     7981 tccgatactc aaagccgaag gcgcaagccg caacagccgc ctgcaactgg caaaactcac
     8041 cggcgacacg ctgaaacaag gcttggattt gctgggcatc gatgtgttgg acgtaatgta
     8101 aaaccgcacc gcccgattgc ggacaacagc ctcgccatcc ttatccgaat ctgaaaaaag
     8161 cggcgcgata caccgtatcc gccgcccctc ccaaaatgcg aaacaaacaa acgccaagca
     8221 agcaagcaag caagcaagca agcaagcaag caagcaaaaa attataaccc ccttcctgcc
     8281 gacgcacgca ctttccgcgc ggcgcattcc cctttttccg cccctcaaac ccgccttttc
     8341 ttcaggcagg gtttcagccc gccccctttc cctgttttcc tttccccgac acgcgcgcgc
     8401 gacccctgcc gcatcgtgcc gcactttcgc gcccggacgg catcgttccg ccatccggtt
     8461 ctctgtttca aatacccctg tttcagaaag aaattctaga tgcttcaaca cacaggacga
     8521 catataaagc gtcgccctat atgttgccct gatttggaag gggttacgcc tcccaaataa
     8581 agtctgatcc tgccgccccg aaggacagat gtccgagtgg cgaagtttca accgaaaagg
     8641 aaatacgatg aatattcaca ccctgctctc caaacaatgg acgctgccgc cattcctgcc
     8701 gaaacggctg ctgctgtccc tgctgatact gcttgccccc aatgcggtgt tttgggtttt
     8761 ggcactgctg accgccaccg cccgcccgat tgtcaatttg gactatcttc ccgccgcgct
     8821 gctgatcgcc ctgccttggc gtttcgtcaa aattgccggc gtattggcgt tttggctggc
     8881 ggttttgttt gacgggctga tgatggtgat ccagcttttc ccttttatgg acctcatcgg
     8941 cgccatcaac ctcgttccct tcatcctgac cgcccccacc ccttatcaga taatgaccgg
     9001 gctgttgctg ctgtatatgc tggcgatgcc gtttgtgttg cagaaagccg ccgccaaaac
     9061 cgacttccgg cacattgccg tctgcgccgc cgttgtggcg gcagccggct atttcaccgg
     9121 ccatttgagt tactacgacc gggggccgat ggccaatatc ttcggcgcaa acaacttcta
     9181 ttacgccaaa agtcaggcga tgctctacac cgtcagccaa aatgccgact ttattaccgc
     9241 cggcctggtc gatcccgtct tcctcccctt gggcaatcaa cagcgtgccg ccacgcatct
     9301 gaacgagccg aaatctcaaa aaatcctctt tatcgtcgcc gaatcttggg ggctgccggc
     9361 caatcccgaa cttcaaaacg ccacttttgc caaactgctg gcgcaaaaag accgtttttc
     9421 ggtttgggaa agcggcagtt ttccctttat cggcgcgacg gtcgaaggcg aaatgcgcga
     9481 actgtgtgcc tacggcggtt tgcgcgggtt tgcactgcgc cgcgcgcccg acgaaaaatt
     9541 tgcccgctgc ctccccaacc gtttgaaaca agaaggttac gccacctttg cgatgcacgg
     9601 cgcgggcagt tcgctttacg accgcttcag ctggtatccg agggcgggct ttcaagaaat
     9661 caaaaccgcc gaaaacctga tcggtaaaaa aacctgtgcc attttcggcg gcgtgtgcga
     9721 cagcgagctg ttcggcgaag tgtcggcatt tttcaaaaaa cacgacaagg gactgtttta
     9781 ctggatgacg ctgaccagcc acgccgacta tcccgaatcc gacattttca accacaggct
     9841 caaatgcacc gaatacggcc tgcccgccga aaccgacctc tgccgcaatt tcagcctgca
     9901 cacccaattc ttcgaccaac tggcggattt aatccaacgc cccgaaatga aaggcgtgga
     9961 agtcatcatc gtcggcgacc atccgccgcc cgtcggcaac ctcaatgaaa ccttccgcta
    10021 cctcaaacag gggcacgtcg cctggctgca cttcaaaatc aaataacaac aatgccgtct
    10081 gaacgcacca acagccttca gacggcattt tgcagacaga ccgacccttc aagcccactt
    10141 ttttcatcat ctccgataaa ttgctttgta tagtggatta acaaaaacca gtacggcgtt
    10201 gcctcgcctt agctcaaaga gaacgattct ctaag
//
LOCUS       DAXIDM010000064        10211 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000064 DAXIDM010000000
VERSION     DAXIDM010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 10211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10211
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.064"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(66..2072)
                     /locus_tag="ACFOAE_001391"
     CDS             complement(66..2072)
                     /locus_tag="ACFOAE_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017628975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HFC6884859.1"
                     /translation="MADMKKITPQNLRPLLSESLGHTDFVNVLNALIKFLRRGGKKCA
                     GERFDLIIDTFKQDRELLSRFSRCFYIWLAQIHIYPALIKLGIFSRHSFAREMGIRIY
                     ERFSPSYKDFANLGEVFLYLFHSENDDKWLQTLNIRQWLVLYELIRSHAEPSKLQTAG
                     IRLADARLRAIEMLSVWTASEAIEPDLIRIAPRLLEADSSFVALQRETAKLVEHYRNG
                     TTPYDTAHLEVMFDQCFSQIDYLRRKGTGAGSGSSVKVAHLLERLRQTVDRLKLLTDI
                     QTGAGNSNRLTIALMNSLIYAAVEQYSTRHLRRSSIRMLARSITENKSHHGEHYITRN
                     RKEYFKMFYSAAGGGIIIALMALLKIRIGTLGLSPFLTSLSAGFNYGIGFMIIHMLHC
                     TVATKQPAMTAASFAEQVDLNEGGKAVDNKLAKLLIDVCRSQSVAVFGNVSIAILLAC
                     AISFGYAHLYRQPILDAHTAAYQFKSIDIIAYPTLWYAAIAGLWLFCSGIIAGFFDNR
                     ADYLNLRQRLPFNPLLRKIMRPGPRRVLAAYIHKHYGSLAGNFIFGMLLGMTGYFGHL
                     LGLPLDIRHVAFSSANLGYAAVSGNVGLGTFVLGIFSVLAIGLVNLCVSFSLALFVAL
                     RSRGTKIGSIRNLIKSFWNQIKSNPCILFLPPAKEQGHPPSDKP"
     gene            2361..4388
                     /locus_tag="ACFOAE_001392"
     CDS             2361..4388
                     /locus_tag="ACFOAE_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HFC6884860.1"
                     /translation="MSLSEFIERRTSFNLMVILTTLFFVCVLVVLVLTVPDQVQMWLD
                     RAKEVIFTEFGWFYVLTFSIFLGFLLILSVSSLGNIRLGRDEDVPEFGFLSWLAMLFA
                     AGMGVGLMFFGVAEPLMHYFSDITAGTPEHRQQQALLHTVFHWGVHAWSVYGTIALAL
                     AYFGFRYKLPLALRSCFYPLLKEKISGRFGDAIDIMALLATFFGIITTLGFGASQLGA
                     GLQEMGWIAENSFSVQVLIIAAVMSLAVVSAISGVGKGVKVLSELNLGLAFLLLFFVL
                     AAGPTVYLLSAFGDNIGNYLGNLVRLSFKTYAYEREHKPWFESWTVLYWAWWCSWAPF
                     VGLFIARISKGRTIREFVFGVLLIPGLFGVLWFTVFGNTAIWLNDGVAGGMLEKMTSS
                     PETLLFKFFNYLPLPELTSIVSLLVISLFFVTSADSGIYVLNNITSRDKGLSAPRWQA
                     VMWGVLMSAVAVLLMRSGGLGNLQSMTLIVSLPFALLMLIMCFSLWKGLSADKKYFET
                     RVNPTSVFWTGGKWKERLVQIMSQTQEQDILKFLKHTASPAMHELQRELSEEYGLSVR
                     VDKMFHQDEPAIEFVIRKETMRDFMYGIKSVGQDVSDQLINDGKLPHIRHQTTYKPYA
                     YFFDGRVGYDVQYMNKDELIADILKNYERYLMLLDDVGQELMAHEQVELAE"
     gene            complement(4480..6033)
                     /locus_tag="ACFOAE_001393"
     CDS             complement(4480..6033)
                     /locus_tag="ACFOAE_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid--CoA ligase"
                     /protein_id="HFC6884861.1"
                     /translation="MNRTYANFYGMLAAACRKNGNGTAVFDGKEKTAYRALKQEAEAV
                     AAYLQNIGVKFGDTVALAVSNSTEFITAYFAVSAIGAVAVPMNTFLKNSEYAYILNDC
                     KARFLFASAGLSKELAGLKAQTPVEKIIWTGQSRPDGEMAEGDAFFEDVRRFPEKPDL
                     GRQPRINDLAHIIYTSGTTGHPKGALISYANLFANLNGIERIFKISKRDRFIVFLPMF
                     HSFTLTAMVLLPIYMACSIILVKSVFPFSNVLKQALLKRATVFLGIPAIYTAMSKAKI
                     PWYFRWFNRIRLFISGGAPLAEQTILDFKAKFPRAKLLEGYGLSEASPVVAVNTPERQ
                     KARSVGIPLPGLEAKAVDEELVEVPRGEVGELIVRGGSVMRGYLNMPAATDETIVNGW
                     LKTGDFVTIDEDGFIFIVDRKKDLIISKGQNVYPREIEEEIYKLDAVEAAAVIGVKDR
                     YADEEIVAFVQLKEGMDLGENEIRRHLRTVLANFKIPKQIHFKDGLPRNATGKVLKRV
                     LKEQFDGNK"
     gene            complement(6069..6221)
                     /locus_tag="ACFOAE_001394"
     CDS             complement(6069..6221)
                     /locus_tag="ACFOAE_001394"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884862.1"
                     /translation="MPDATGIRLRHWKDAGEPPAYGAKAAFDMPSEGKDDKLPPSVFR
                     RHIVFK"
     gene            complement(6320..7513)
                     /locus_tag="ACFOAE_001395"
     CDS             complement(6320..7513)
                     /locus_tag="ACFOAE_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFC6884863.1"
                     /translation="MNPKHLIAFSALFAATQAEALPVASVSLDTVTVSPSAPYTDTNG
                     LLTDYGNAAASPWMKKLQSVAQGSGETFRILQIGDSHTAGDFFTDSLRKRLQKTWGDG
                     GIGWVYPANVKGQRMAAVRHNGNWQSLTSRNNTGDFPLGGILAHTGSGGSMTLTASDG
                     KTGKQRISLFAKPLLAEQTLTVNGNTVSANGGGWQVLDTGAALPLTIQTEMPWDIGFI
                     NIENPAGGITVSAMGINGAQLTHWSKWRADRMNDLAQIGADLVILSYGTNEAFGDNID
                     IADTEQKWLDTVRQIRDSLPAAGILIIGAPESLKNTLGVCGTRPVRLTEVQQMQRRVA
                     RQGQTMFWSWQNAMGGICSMKNWLNHGWAAKDGVHFSAKGYRRAAEMLADSLEELVRA
                     AAIRQ"
     gene            complement(7510..8493)
                     /gene="patB"
                     /locus_tag="ACFOAE_001396"
     CDS             complement(7510..8493)
                     /gene="patB"
                     /locus_tag="ACFOAE_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003702842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan O-acetyltransferase PatB"
                     /protein_id="HFC6884864.1"
                     /translation="MKNFLSLFASILMSALIAVWFSQNPINAYWQQTYHRNSPLEPLA
                     AYGWWRSGAALQENAYTLSDGIKAFLSGETPPTAQDGGSADMPSEAAASEAAPQTGKT
                     EWKQDTAAAAVRSGDKVFFAGDSLMQGVAPFVQKSLKQQYGIESVNLSKQSTGLSYPS
                     FFDWPKTIEETLQKHPEISVLAVFLGPNDPWDFPVGKRYLKFASDEWAQEYLKRVDRI
                     LEAAHTHHVQVVWLGIPYMKKAKLDGQMRYLDKLLSEHLKGKIILIPTAHTLSGGEDR
                     YTDSVNVNGKPVRYRSKDGIHFTAEGQKLLAAKIMEKIVFEPSTQPSSTQP"
     gene            complement(8504..9940)
                     /locus_tag="ACFOAE_001397"
     CDS             complement(8504..9940)
                     /locus_tag="ACFOAE_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HFC6884865.1"
                     /translation="MPLLSVEFALFFLAFLPIYWGLAKYPSVQNLLLLAAGMGWLYHI
                     GPVFAAIIVLYSSCVYLLGELLRSDRENTRRFWLGCGIAASLTVLGFFKYFDFFRPMI
                     AQYAGKGGAIDILMPLGLSYYTFQSLAYLVYCFRAPHAARFEWHELLLHLSFFPTVTS
                     GPIIRAAAFKSADGEQAGALAQIRTHQPRSPVRPALAVSLILLGIAKKWWLAGMLAEN
                     WVSPVFENPAQFDGWGVLAGVYGYTFQLFLDFSGYSDLVIGMAMLLGFRLPKNFSAPL
                     RAANIRAFWDKWHISLSTWIRDYIYIPLGGSKKGFLRTQFNLMAAMVLSGIWHGYGWN
                     FLIWGALHGTALVLLNTGDRYFGRNALCRLKYLAPLSWFVTFHFVCLSFVVFNTASPD
                     DAGAVFNALFANANGWNAPQQANMLLLASFASVMLLYPYLQRAFDGAVKGLEKIPMWL
                     WFIPVSAVLLLIIVLAPSGIPGFIYANF"
     gene            complement(10068..>10211)
                     /locus_tag="ACFOAE_001398"
     CDS             complement(10068..>10211)
                     /locus_tag="ACFOAE_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HFC6884866.1"
                     /translation="NVGIGSGALLGHWVTQYVGISRIGIAGMLAAAAGLWLCLNLNRH
                     IRT"
BASE COUNT         2099 a         2456 c         3213 g         2443 t
ORIGIN      
        1 tttatgggga tttcccgcat cagggcggta ttcggggcga atcccgcttc agacggcatt
       61 gccggtcaag gcttgtccga aggaggatgt ccctgttctt tggcgggcgg gaggaaaagt
      121 atgcagggat tgcttttaat ctgattccaa aaactcttaa tcagattgcg gatgctgccg
      181 attttcgtgc cgcgcgagcg cagggcgacg aagagggcga ggctgaagct gacgcagagg
      241 ttgaccaggc cgatggcgag gacgctgaaa atgccgagta cgaacgtgcc caaaccgacg
      301 ttgccgctga cggcggcata gccgaggttg gcggaggaaa aggcgacgtg gcggatgtcc
      361 agcggcagcc cgaggaggtg tccgaaatag ccggtcatac ccaagagcat cccgaagatg
      421 aagttgcctg ccaacgagcc gtagtgtttg tggatgtagg cggcgaggac gcggcggggc
      481 ccggggcgca tgattttacg cagcaagggg ttgaagggca ggcgttggcg caggttgagg
      541 tagtcggcgc ggttgtcgaa aaaacctgcg atgatgccgg agcagaacag ccacagacct
      601 gcaatggcgg cataccacag cgtcgggtaa gcgatgatgt ctatggattt gaactggtag
      661 gcggcggtgt gggcatcgag tatgggctgc cggtacagat gggcatagcc gaacgatatg
      721 gcgcacgcca aaaggatggc gatggaaacg ttgccgaaaa cggcgacact ttgggaacgg
      781 catacgtcga tgaggagctt ggcgagtttg ttgtccaccg ctttgccgcc ttcgttgaga
      841 tcgacctgtt cggcaaagct ggcggcagtc atcgcgggct gtttggtggc gacggtgcag
      901 tgcagcatat ggatgatcat aaagccgatg ccgtagttga acccagccga caaggaagtc
      961 aggaaggggc tgaggccgag tgtgccgatg cggattttga gcagcgccat cagggcgatg
     1021 atgatgccgc cgcctgccgc cgagtagaac attttgaaat attctttgcg gttgcgggta
     1081 atgtagtgtt cgccgtggtg gcttttgttt tcggtaatgc tgcgggcgag catacggatg
     1141 ctgctgcggc gcaggtggcg ggtgctgtat tgttcgaccg ccgcgtagat gagggagttc
     1201 atcagcgcga tggtcaggcg gttgctgttg ccggcgccgg tttggatgtc ggtgagcagc
     1261 ttcagacggt ctacggtctg ccggagccgt tcgagcaggt gggcgacttt gaccgacgaa
     1321 ccggagccgg cgcccgtccc tttgcggcgc aaatagtcaa tctggctgaa acattggtcg
     1381 aacatcactt cgaggtgggc ggtgtcgtaa ggcgtggtgc cgttgcggta gtgttcgacc
     1441 agtttggcgg tttcgcgttg gagggcgacg aaggaagaat cggcttccag caggcgcggg
     1501 gcgatgcgga tgaggtcggg ttcgatggct tcggatgccg tccagacaga cagcatttcg
     1561 atggcgcgca aacgcgcatc ggcaaggcgg atgcccgccg tctgcaattt ggacggctcg
     1621 gcgtggctcc ggatgagttc gtataaaacc agccattggc ggatattgag cgtttgcagc
     1681 catttgtcgt cgttttcgga atggaaaaga taaaggaaga cttcgcccaa gttggcaaaa
     1741 tctttatatg acgggctgaa gcgttcgtag atgcgtatgc ccatttcccg ggcaaagctg
     1801 tggcgcgaga agatgccgag tttgatgagt gccggataaa tgtgtatttg cgcgagccag
     1861 atgtaaaaac accggctgaa gcgggacagc aattccctgt cttgtttgaa tgtgtcgata
     1921 atcaggtcga aacgttcccc cgcacatttt ttgccgccac ggcgcaaaaa tttaatcagt
     1981 gcgttgagga cgttgacaaa atcggtatgt cccaagcttt ccgaaagcag ggggcgcagg
     2041 ttttgagggg taattttctt catatcagcc attgtaccgc atcggcaatc tggcgttaaa
     2101 cgccccgatg gcggggaggg cgcgcctgcg gtgggcggcg cattttccgc cggtttgaaa
     2161 tcaaactata ttaatgatat aataaatatc gataaatcaa tctgatagaa taatccgtat
     2221 tgatttttaa ttttttcgat tataacaatt tcggccggtt tgtgcatttc gtcatccgga
     2281 agccggtatt ttgccggcag gttttgaccg ctttgcccga tgaccgggtt tgtctgtttt
     2341 taacaaagga gtgagaaggt ttgtccctgt ctgaatttat agaacgccga acgtcattta
     2401 atctgatggt tattttgacg actttgtttt ttgtgtgtgt tttggtggta ttggttttaa
     2461 ccgtgccgga tcaggtgcag atgtggctcg atcgggcaaa agaagtcatt tttaccgagt
     2521 tcggctggtt ttatgtttta acgttttcca tttttctggg tttcctgctg atactctcgg
     2581 tcagcagttt gggaaacatc aggctcggac gggatgaaga tgtgccggaa ttcggcttcc
     2641 tgtcgtggct ggcgatgctg tttgcggccg ggatgggcgt gggtctgatg tttttcggcg
     2701 tggcagagcc gttgatgcat tatttttcgg acattacggc cggcacgccg gaacacaggc
     2761 agcagcaggc attgctgcac acggtgttcc attggggcgt tcacgcttgg tcggtgtacg
     2821 gtacgattgc attggctttg gcttatttcg gtttccgcta caagctgccg cttgccctgc
     2881 gttcttgttt ttaccccctg ttgaaagaaa aaatttccgg aaggttcggc gatgccattg
     2941 atattatggc gttgcttgct acttttttcg gcatcatcac cacattgggg ttcggggctt
     3001 cgcaactggg cgccggattg caggaaatgg gctggattgc cgaaaacagc ttcagcgtgc
     3061 aggttttgat tatcgccgcc gtcatgtccc tcgccgtcgt ttcggcaata tccggcgtgg
     3121 ggaagggcgt gaaggtgttg agcgagttga acctgggcct tgcgtttttg ctgctgtttt
     3181 ttgttttggc ggcgggaccc actgtttacc tgttgtcggc attcggcgac aacataggga
     3241 actacctcgg aaatctggtg cgcctcagtt ttaaaactta tgcgtacgaa cgggaacaca
     3301 agccgtggtt tgaatcttgg acggtgcttt attgggcgtg gtggtgttct tgggcgccgt
     3361 ttgtgggttt gtttatcgcg cgcatttcaa aggggcgcac catccgcgag tttgtcttcg
     3421 gggttttgct catccccggc ctgttcggcg ttttgtggtt taccgtcttc ggcaatacgg
     3481 cgatttggct gaatgacggg gttgcggggg gaatgctcga aaagatgacc tcctctccgg
     3541 aaacgctgct ttttaaattc tttaattacc tccccctgcc cgaattgacg agcatcgtca
     3601 gcctgctggt catttctctg ttttttgtaa cttctgccga ttccgggatt tatgtcctga
     3661 acaatattac ctctcgggac aagggcttga gcgcaccacg gtggcaggcg gttatgtggg
     3721 gcgtgctgat gtctgccgtt gccgttttgc tgatgcgctc gggcgggcta ggcaacctgc
     3781 agtctatgac cctgattgtt tccctgccgt ttgccctgct gatgctgata atgtgtttca
     3841 gcctgtggaa aggattgagt gcggataaga aatattttga gacccgggtt aaccctacca
     3901 gtgtattttg gacgggcggc aagtggaaag aacggctggt gcagataatg agccagacgc
     3961 aggagcagga tattttaaaa ttcctcaaac ataccgcatc gcccgctatg cacgagttgc
     4021 aacgggagct ttcggaagaa tacggcttga gcgtccgggt cgataagatg tttcatcagg
     4081 acgagcccgc aatcgagttc gtcattcgga aagagacgat gcgcgatttt atgtacggga
     4141 ttaagtctgt cgggcaggat gtatccgacc agttgattaa cgacggcaag ctgccgcata
     4201 tccggcatca gacaacttac aaaccctacg cttatttttt cgacgggcgc gtcgggtacg
     4261 atgtgcagta tatgaacaag gacgagctga ttgccgacat tttgaaaaac tacgaacgtt
     4321 atttgatgtt gttggatgat gtcggtcagg aactgatggc gcacgagcag gtggaattgg
     4381 cagagtaagt gccttatctc cggtgtttgc caaaaaaaat gcggtgaatc agattcaccg
     4441 catttttttt gccggacggg gcttcggacg gcacggcgtt catttgtttc cgtcaaactg
     4501 ctccttcaac acccgtttca ataccttgcc cgtagcgttg cgcggcagcc cgtctttaaa
     4561 gtggatttgt ttggggattt tgaaatttgc cagcacggta cgcaggtggc ggcggatttc
     4621 gttctcgccc aaatccatac cttccttcaa ttggacgaag gcgacgattt cctcgtcggc
     4681 ataacggtct ttcacgccga tgacggcggc ggcttcgacg gcatcgagtt tgtagatttc
     4741 ttcttcgatt tcgcgcggat agacgttttg acctttggaa ataatcaaat cttttttgcg
     4801 gtcgacgata aagataaagc cgtcttcgtc tatggtaacg aaatcgcccg ttttcaacca
     4861 gccgttgacg atggtttcat cggtggcggc aggcatattg aggtagcccc gcatcaccga
     4921 accgcccctg acgatcagtt cgcccacttc gccgcgcggc acttcgacca attcttcatc
     4981 gacggctttg gcttccaaac cgggcagggg gatgccgacg ctgcgggctt tttgcctctc
     5041 gggcgtattg acggcgacga cgggagaggc ttcgctcagt ccgtagcctt ccagcaattt
     5101 ggcgcgaggg aacttggctt tgaaatcgag gatggtttgt tccgccaaag gcgcaccgcc
     5161 gctgataaac aggcgaatgc ggttgaacca tctgaaatac caagggattt tcgccttgct
     5221 cattgcggtg taaatcgcgg gtatgcccaa aaacacggtc gcgcgtttga gcagggcctg
     5281 tttcaaaacg ttggaaaacg gaaaaacgga tttgaccaaa ataatcgaac acgccatata
     5341 aatcggcagc agcaccatag ccgtcagcgt gaagctgtgg aacatcggca ggaaaacgat
     5401 aaagcggtcg cgtttggaga ttttaaagat gcgttcgatg ccgttcaggt tggcgaacag
     5461 gttggcgtaa ctgattagcg cacctttggg atgccccgtc gtgccggagg tgtagatgat
     5521 gtgtgccaaa tcatttatcc ggggttggcg gcccaagtcg ggtttttcgg ggaagcggcg
     5581 cacgtcttca aaaaaggcat cgccttccgc catttcgccg tccggacggc tttggcccgt
     5641 ccaaatgatt ttttcgacgg gcgtttgcgc cttcaagccc gccaattctt ttgacaggcc
     5701 ggccgaggcg aacaggaagc gcgccttgca gtcgttcagg atatacgcgt attcgctgtt
     5761 tttcaaaaat gtgttcatcg gtacggcaac cgcgccgatg gcggatacgg cgaaataggc
     5821 ggtaataaat tccgtggaat tggaaaccgc cagcgcgacc gtgtcgccga acttcacgcc
     5881 gatattttgc agatacgccg caacggcttc ggcttcctgc ttgagcgcgc ggtaggcggt
     5941 tttttccttg ccgtcgaaca ctgccgtgcc gttgccgttt ttgcggcagg cggcggcgag
     6001 cattccgtag aaattggcat aagtccggtt catgaaactt cctttatggt tgcggacggc
     6061 gaacgccctc atttgaaaac aatatgccgt ctgaaaacgg aaggcggcag tttatcatct
     6121 ttgccttcag acggcatatc aaacgccgcc tttgcgccgt atgccggagg ttcgcctgcg
     6181 tctttccaat gtctgaggcg aatgccggtt gcgtccggca aaccgtgcgc ggggtggcta
     6241 tgccgtctga agcaatatga aggtatgcgt ttcagacggc atccccctgt tgcggaaata
     6301 ccgtccgcct cctgtccgat tattgcctga ttgcagcggc gcggacgagt tcttcgaggc
     6361 tgtcggcgag catttccgcc gcgcgccggt agcctttggc ggaaaagtgt acgccgtctt
     6421 tggcggccca tccgtggttg agccagtttt tcatgctgca tatgccgccc atggcgtttt
     6481 gccaagacca gaacatggtt tgtccctgcc gggcgacgcg ccgctgcatc tgttggactt
     6541 cggtcaggcg gacggggcgt gtgccgcata cgccgagcgt gtttttcagg gattcgggtg
     6601 cgccgatgat gaggatgccg gcggcaggca ggctgtcgcg gatttggcgg acggtatcca
     6661 gccatttttg ttcagtgtcg gcaatgtcga tgttgtcgcc gaaggcttcg ttggtgccgt
     6721 aggaaaggat aaccaaatcg gcgccgattt gggcaaggtc gttcatacgg tcggcacgcc
     6781 atttcgacca atgggtcaat tgtgcgccgt tgatgcccat ggcggaaacg gtaatgccgc
     6841 cggcgggatt ttcgatgttg atgaagccga tgtcccacgg catttcggtc tgtatggtca
     6901 gtgggagtgc cgcgcccgta tccagtacct gccagccgcc gccgttggcg gagacggtgt
     6961 tgccgttgac ggtcagggtt tgttcggcga gcaggggttt ggcaaacagg gagatgcgct
     7021 gtttgccggt cttgccgtcc gatgcggtca gggtcatgct gccgccgctg ccggtgtggg
     7081 cgaggatgcc gccgaggggg aaatctccgg tgttgttcct gctggtgagg ctttgccagt
     7141 tgccgttgtg ccggacggcc gccatgcgct gccctttgac gttggcgggg taaacccagc
     7201 ctatgccgcc gtcgccccat gttttttgca ggcgtttgcg caggctgtcg gtaaagaagt
     7261 cgccggcggt gtgcgagtcg ccgatttgca ggatgcggaa ggtctcgccg ctgccttgtg
     7321 cgacggattg gagttttttc atccaaggcg aggcggcggc attgccgtag tcggtcaaga
     7381 gcccgtttgt atcggtgtag ggggcggacg gggaaacggt aacggtgtcg aggctgacgg
     7441 aggcgacggg cagggcttct gcctgcgtgg cggcgaacag ggcggaaaat gcgatgaggt
     7501 gtttggggtt catggctgtg tacttgatgg ttgcgtactt ggttcaaaaa cgattttttc
     7561 cattattttt gccgccagca gtttttgtcc ttcggcggta aagtgtatgc cgtccttgct
     7621 gcggtagcgg acgggtttgc cgttgacgtt gacggaatcg gtgtagcggt cttccccgcc
     7681 gctcagggtg tgcgcggtgg gaatcaggat gattttgcct ttcaaatgtt ccgaaagcag
     7741 tttgtcgagg tagcgcatct gcccgtcaag cttggctttt ttcatgtagg ggatgccgag
     7801 ccagacgact tggacgtggt gcgtgtgtgc ggcttcaagg atgcggtcga cgcgtttcag
     7861 gtattcttgc gcccattcgt cggaagcgaa tttgaggtag cgtttgccga cggggaaatc
     7921 ccacgggtcg ttcgggccga ggaagacggc gagcacgctg atttcgggat gtttttgcag
     7981 ggtttcttca attgttttcg gccagtcgaa gaatgagggg taggacagcc ctgtgctttg
     8041 tttgctgagg ttgacggatt cgatgccgta ttgctgtttc aggctttttt gcacgaaggg
     8101 ggcaacgccc tgcatcagcg agtcgccggc gaaaaagact ttgtcgccgc tgcggacggc
     8161 tgcggcggcg gtgtcctgtt tccattctgt tttgccggtt tgaggggcgg cttcggatgc
     8221 ggcggcttca gacggcatat ccgccgaacc gccgtcttga gccgtcggcg gcgtttcgcc
     8281 ggacaggaag gctttgatgc cgtctgaaag ggtgtaggcg ttttcttgca atgccgcacc
     8341 gctccgccac catccgtagg cggcaagcgg ttcgagcggg ctgttgcggt ggtaggtctg
     8401 ctgccagtag gcgttgatgg ggttttggct gaaccacacg gcaatcaggg cagacatcag
     8461 tatggaggcg aaaagggaaa gaaagttttt catgtccaaa cccttaaaaa ttggcataaa
     8521 taaagccggg tatccccgag ggggccaata cgataatcag cagcaggacg gcggaaacgg
     8581 ggataaacca cagccacatc gggatttttt ccaaaccttt gaccgcgccg tcgaaagcgc
     8641 gttgcaggta agggtagagc agcatcacgg atgcaaacga ggcaagcagc agcatgtttg
     8701 cctgttgcgg cgcattccag ccgttggcat tggcaaagag ggcattgaaa actgcgcctg
     8761 catcgtcggg gcttgcggta ttgaagacaa caaagctaag gcagacgaaa tggaaggtaa
     8821 caaaccacga gagcggcgca aggtatttca gacggcatag cgcgttgcgt ccgaaatagc
     8881 gatcgcccgt gttgagcagc accagcgccg tgccgtgcag cgcgccccaa atgaggaagt
     8941 tccagccgta gccgtgccag atgcctgaga gcaccattgc cgccatcagg ttgaactgtg
     9001 tccgcaaaaa gccttttttg ctgccgccca aggggatgta gatgtagtcg cgtatccagg
     9061 tggaaaggct gatgtgccat ttgtcccaaa atgcgcggat attcgcggca cgaagcggtg
     9121 cggagaagtt tttgggcagc cggaagccca gcagcattgc cattccgata accaagtcgg
     9181 aatatccgga aaagtctaaa aagagttgga aggtatagcc gtacacgccc gccaatacgc
     9241 cccagccgtc gaattgggcg ggattttcaa atacgggcga tacccagttt tctgcgagca
     9301 tccccgccag ccaccatttt ttggcaatac ccagcagaat cagggaaacg gcgagtgcgg
     9361 ggcggacggg tgagcgtggt tggtgggtac ggatttgcgc caatgcgccc gcctgctcgc
     9421 cgtctgcgct tttgaatgcg gcggcgcgga taatcgggcc ggaggtaacg gtggggaaaa
     9481 aactcaggtg cagcagcagc tcgtgccact cgaaacgcgc ggcgtgcggg gcgcggaagc
     9541 agtaaaccag ataggcgagc gactggaagg tgtaatagga aagccccagc ggcatcagga
     9601 tgtcgattgc gccgcctttt ccggcatatt gggcaatcat cgggcggaaa aagtcgaaat
     9661 atttgaaaaa gcccaagacg gtcagcgagg cggcaatgcc gcaccccagc cagaaacggc
     9721 gcgtattttc gcgatcggaa cggagcagtt cgcccaaaag gtacacgcag gaggaataaa
     9781 ggacgatgat tgccgcaaat acggggccga tatggtagag ccagcccata ccggcagcca
     9841 aaagcagcag gttttggacg gacgggtatt tcgccaagcc ccagtaaatc ggcaggaagg
     9901 cgagaaagaa cagtgcgaac tcgacagaca gcagcggcat aaaccatcct tggaacaaaa
     9961 aataggcgtt aaaacacggc aaagcccgtt attttaagca ggggtggata tttcttcaat
    10021 caaaatgccg tctgaagggc gggagaggct ttagacggca tagcgggtca ggttcggata
    10081 tggcggttca agttcaggca cagccacagc ccggccgccg ccgcaagcat accggcgatg
    10141 ccgatacggg aaataccgac atattgcgtt acccaatgtc ccaacagtgc gccgctgccg
    10201 ataccgacgt t
//
LOCUS       DAXIDM010000065         9947 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000065 DAXIDM010000000
VERSION     DAXIDM010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9947
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.065"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(134..1576)
                     /gene="aldA"
                     /locus_tag="ACFOAE_001399"
     CDS             complement(134..1576)
                     /gene="aldA"
                     /locus_tag="ACFOAE_001399"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HFC6884867.1"
                     /translation="MKQLAMYINGRFENDFNGEWRDVLNPSTEETIAREPKGGRADVD
                     RAVAAARAAQPAWERLPAVERGAYLRKIAQGIRERADELTDTIVAEGGKTKDLARVEV
                     MFTADYLDYQAEWARRYEGEIIQSDRPRENILLFKRPLGVIAGILPWNFPFFLIARKM
                     GPALVTGNTIVVKPSSVTPINCHIFAEIVDAVGLPAGVFNVVNGPGAEIGNALSAHPQ
                     VDMVSLTGSVEAGRQVMEAASANITKVSLELGGKAPAIVLKDADLDLAVKSILASRVG
                     NTGQICNCAERVYVHSSLKDAFIEKMTAAMKGVRYGNPAEAEAGALEMGPLIEERAVK
                     AVAEKVERAVKQGAKLVCGGKRAEGRGYFFEPTLLTDTDNSMDIMKEETFGPVLPVSA
                     FDTLDQVIALANDCEFGLTSSVYTTNLNEAFYVTRRLQFGETYINRENFEAMQGFHAG
                     WKKSGIGGADGKHGLEEYLQTQVVYLETDI"
     gene            complement(1611..1811)
                     /locus_tag="ACFOAE_001400"
     CDS             complement(1611..1811)
                     /locus_tag="ACFOAE_001400"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884868.1"
                     /translation="MDTVGSLAIGYATGGNAGAFTDANADWNNRQLHSSEYKLAEQYA
                     DIVASRLNISKETCTAIYLGIN"
     gene            complement(1820..2209)
                     /locus_tag="ACFOAE_001401"
     CDS             complement(1820..2209)
                     /locus_tag="ACFOAE_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884869.1"
                     /translation="MLYKCKIKKLDNTIEEAVLIEINGYELHCFISYCPFKIFENQFY
                     EVELSYEIFNDYILDKSTSNIGFRKIDDSFKYEITAELKNNHLTLQNIQFEEDEYLVN
                     YSYLDNCLVTLTADRISVSFIREIQAA"
     gene            complement(2418..3335)
                     /locus_tag="ACFOAE_001402"
     CDS             complement(2418..3335)
                     /locus_tag="ACFOAE_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC6884870.1"
                     /translation="MEKAEHLNSSRFVNLVKSGGGSYVEGSYRFDTLSNGISIHGGTV
                     TARCDFCSSRLAEPYVSFVLLLEGSLDFGINRRRFQIDADGGKIVLIAVGEEVLFSRY
                     LYRGGKTVKMTIKGMEQWLLRPEYARFAPLLYREPVRIWDLPPNLRGLAASCLKAVPK
                     GHLGETLRREADVLRLLSDLWDTVSDGIGPAAGQTAEADAMPSEDFSRTLNAAFADGA
                     HQVNRLTDALNISERTLQRRMRDHFGITASEWLHHKQMQHALYLLQNGGKSIGETAYL
                     CGYRHVSSFTQAFRQYFGSTPAETKKENR"
     gene            3507..4307
                     /locus_tag="ACFOAE_001403"
     CDS             3507..4307
                     /locus_tag="ACFOAE_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC6884871.1"
                     /translation="MSPSPFIEMKDVAFAYGDRPILKNINFSIPQGNFAAVMGGSGSG
                     KTTLMRLITGQIRPQSGQVLIEGRDLAGFSADELYEHRRRMGVLFQHGALFTDLSVFD
                     NIAFPMRELTRLPEAVIRDLVLLKLNAVGLRGVENLMPSELSGGMSRRVALARTIALD
                     PEIMLYDEPFTGLDPISLGVIAHLISRVNKALRSTSIMVTHDIEKSLEIVDQVIFLAH
                     GEIMFSGSPQEMRELDSPWVRQFVGGLADGPVAYRYPAQTSLQQDLLG"
     gene            4356..5132
                     /gene="mlaE"
                     /locus_tag="ACFOAE_001404"
     CDS             4356..5132
                     /gene="mlaE"
                     /locus_tag="ACFOAE_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HFC6884872.1"
                     /translation="MNFIRSVGAKTLGLIQSLGSITLFLLNILAKSGTAFVRPRLSVR
                     QVYFAGVLSVLIVAVSGLFVGMVLGLQGYTQLSKFKSADILGYMVAASLLRELGPVLA
                     AILFASSAGGAMTSEIGLMKTTEQLEAMNVMAVNPVARVVAPRFWAGVFSMPLLASIF
                     NVAGIFGAYLVGVTWLGLDSGIFWSQMQNNITIHYDVINGLIKSAAFGVAVTLIAVHQ
                     GFHCVPTSEGILRASTRTVVSSALTILAVDFILTAWMFTD"
     gene            5183..5677
                     /gene="mlaD"
                     /locus_tag="ACFOAE_001405"
     CDS             5183..5677
                     /gene="mlaD"
                     /locus_tag="ACFOAE_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015914 - phospholipid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HFC6884873.1"
                     /translation="MKKNILEFWVGLFVLIGAAAVAFLAFRVAGGAAFGGSDKTYAVY
                     ADFGDIGGLKVNAPVKSAGVLVGRVGAIGLDPKSYQARVRLDLDGKYQFSSDVSAQIL
                     TSGLLGEQYIGLQQGGDTENLAAGDTISVTSSAMVLENLIGKFMTSFAEKNADGGNAE
                     KAAE"
     gene            5714..6304
                     /locus_tag="ACFOAE_001406"
     CDS             5714..6304
                     /locus_tag="ACFOAE_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HFC6884874.1"
                     /translation="MKKSSLISALGIGILSIGMAFAAPADAVNQIRQNATQVLSILKN
                     GDANTARQKAEAYAIPYFDFQRMTALAVGNPWRTASDAQKQALAKEFQTLLIRTYSGT
                     MLKLKNANVNVKDNPIVNKGGKEIIVRAEVGVPGQKPVNMDFTTYQSGGKYRTYNVAI
                     EGASLVTVYRNQFGEIIKAKGVDGLIAELKAKNGSK"
     gene            6361..6639
                     /locus_tag="ACFOAE_001407"
     CDS             6361..6639
                     /locus_tag="ACFOAE_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HFC6884875.1"
                     /translation="MHTELNNGTLHISGDITVKTLTAAAFTRFRQQCRLKDTCAVDLS
                     GVGRADSACVSLLLEVLRGCKGSVRLTGIPESVRALSELYEIKDWLKS"
     gene            6636..7463
                     /locus_tag="ACFOAE_001408"
     CDS             6636..7463
                     /locus_tag="ACFOAE_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ family lipoprotein"
                     /protein_id="HFC6884876.1"
                     /translation="MKKTAYAFLLLIGFASAPAFAETRPADPYEGYNRAVFKFNDQAD
                     RYIFAPAARGYRKVAPKPVRAGVSNFFNNLCDVVSFGSNILRLDIKRASEDLVRVGIN
                     TTFGLGGLIDIAGAGGIPDNKNTLGDTFASWGWKNSNYFVLPVLGPSTVRDALGTGIT
                     SVYSPKNIVFRTPVGRWGTTAVSAVSTREGLLDLTDSLDEAAIDKYSYTRDLYMKVRA
                     RQTGATPAEGTEDNIDIDELVESAETGAAETAVQEDSVSETQAEAAGEAETQPGTQP"
     gene            7588..7950
                     /locus_tag="ACFOAE_001409"
     CDS             7588..7950
                     /locus_tag="ACFOAE_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003681812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VacJ"
                     /protein_id="HFC6884877.1"
                     /translation="MYEVNRSVFVLIPLEPFWNWLQTLPGNHLDGLTLEDIQADANSY
                     LVRPCETADEVWDEIEARFEDIFAAELADWCEDEREWPALDADIFNEWFDIQLSTVIT
                     DLEHEPLAREAFQPINLN"
     gene            7950..8333
                     /locus_tag="ACFOAE_001410"
     CDS             7950..8333
                     /locus_tag="ACFOAE_001410"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFC6884878.1"
                     /translation="MKLTVRNYHLDGYGHVNNARYLEFFEEARWAFFEERGLLHELAG
                     LILIVARIDIRYSRPAVEGDVLQFSCRLKTPGTRRIVLTQTITLPNGKTAAEADITLM
                     PVHAATQRTVSLPATLARALEALSE"
     gene            8330..8818
                     /locus_tag="ACFOAE_001411"
     CDS             8330..8818
                     /locus_tag="ACFOAE_001411"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin family protein"
                     /protein_id="HFC6884879.1"
                     /translation="MKKILTAAVVALIGILLAIVLIPDSKTAPAFSLPDLHGKTVSNA
                     DLQGKVTLINFWFPSCPGCVSEMPKIIKMANYYKNKNFQVLAVAQPIDPIESVRQYVK
                     DYGLPFTVMYDADKAVGQAFGTQVYPTSVLIGKKGEILKTYVGEPDFGKLYQEIDTAL
                     AQ"
     gene            complement(8901..9029)
                     /locus_tag="ACFOAE_001412"
     CDS             complement(8901..9029)
                     /locus_tag="ACFOAE_001412"
                     /inference="COORDINATES: protein motif:HMM:NF025953.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFC6884880.1"
                     /translation="MAGVTVGRGSVVGAGAVVTKDIPPYSLAAGNPAVVKKNLPEG"
     gene            complement(9035..9415)
                     /locus_tag="ACFOAE_001413"
     CDS             complement(9035..9415)
                     /locus_tag="ACFOAE_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-o"
                     /protein_id="HFC6884881.1"
                     /translation="MGSKFFFLLLRFAGSGLPPSHMRGIGIVGRRVRGFLARRVSPHI
                     GRGVNIERGAYVFPDTVLGDGSGIGANCEICRGLVVGKNVMMEPECLFYSNNHKFDRS
                     KNALRATRKSVRLRWRTMSGRGTG"
     gene            9653..9868
                     /gene="rpmE"
                     /locus_tag="ACFOAE_001414"
     CDS             9653..9868
                     /gene="rpmE"
                     /locus_tag="ACFOAE_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003681847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HFC6884882.1"
                     /translation="MKQGIHPNYHEVNVTCSCGNKFATKSAMEKENFNIEVCSLCHPF
                     YTGTQKIVDTTGRVDKFNNKFGNLFKR"
BASE COUNT         2331 a         2767 c         2479 g         2370 t
ORIGIN      
        1 taaatttaat ccgctataca aagacaaaaa catcgacctc ggtcatgact gattgccgat
       61 gaagcaataa aaatgccgtc tgaacctgaa aacgggttca gacggcattt tctatcgggg
      121 ttttaaagcg gcattaaatg tcggtttcca aataaacgac ttgggtttgc agatattctt
      181 ccaaaccgtg tttgccgtcc gcaccgccga tgccggattt tttccaaccg gcgtggaaac
      241 cctgcatcgc ttcaaagttt tcgcggttga tgtaggtttc gccgaattgc aggcggcggg
      301 taacgtagaa ggcttcgttt aaattagtcg tataaacaga actggtcaga ccaaactcgc
      361 aatcgttagc caaggcgatg acttggtcga gcgtgtcgaa agcggaaacg ggcagaacgg
      421 ggccgaaggt ttcttctttc ataatgtcca tactgttgtc ggtgtcggtc agcagggtcg
      481 gctcgaagaa atagccgcgt ccttcggcgc gtttgccgcc gcaaaccagt ttcgcacctt
      541 gtttgactgc ccgttccact ttttcggcaa cggctttgac tgcgcgctct tcaatcagcg
      601 ggcccatttc cagcgcgcct gcttcggctt cggcagggtt gccgtagcgt acgcctttca
      661 tggcggcagt cattttttca atgaacgcgt ctttcaggct gctgtggaca taaacgcgct
      721 cggcgcagtt gcagatttga ccggtgttgc cgacgcgcga agccaagatg gatttcactg
      781 ccaagtccaa atccgcgtct ttcaaaacga tggcgggcgc tttgccgccg agttccagcg
      841 aaactttggt aatgttggcg gaagcggctt ccatcacttg gcggcctgct tcgacggagc
      901 cggtcaggct gaccatatcg acttgcggat gggcggacaa ggcattgccg atttccgcac
      961 cggggccgtt cactacgttg aacacgcctg cgggcagtcc gaccgcatcg acgatttcgg
     1021 cgaagatgtg gcagttgatc ggggttacgc tgctgggttt gacgacgatg gtgttgcccg
     1081 ttaccaaagc gggacccatt ttgcgggcaa tcaggaagaa ggggaagttc cacggcaaaa
     1141 tgccggcaat tacgcccagc ggacgtttga acaataaaat gttttcgcgc gggcggtcgc
     1201 tttggatgat ttcgccttca taacggcgcg cccattcggc ttggtaatcg agatagtcgg
     1261 cggtgaacat cacttccacg cgcgccaagt ctttggtttt gccgccttcg gcaacgatgg
     1321 tgtcggtcag ctcgtcggcg cgttcgcgta tgccttgggc gattttgcgc aaatatgcgc
     1381 cgcgttcgac cgcaggcagc cgctcccatg ccggttgcgc cgcgcgtgcc gccgctacgg
     1441 cgcggtcaac gtccgccctg ccgcctttgg gttcgcgggc gatggtttct tcggtggatg
     1501 ggttcaatac gtcgcgccat tcgccgttga aatcgttttc aaagcgtccg ttgatgtaca
     1561 tggccaattg tttcatttcg ggttctccag ttttgtagtc agatgtagtc ttagtttatt
     1621 cccaaataaa ttgccgtaca agtttctttt gaaatgttta gacgagaagc tactatgtct
     1681 gcatattgtt ctgctaattt atattcactc gaatgcaact gccgattatt ccaatctgca
     1741 ttcgcatcag taaaagcccc agcattgccg cctgtggcat aaccaatcgc taaactgcca
     1801 acggtatcca caacaggttt caggctgcct gaatttctct aataaatgaa acacttattc
     1861 tatcagccgt taatgtaacc aaacaattat caagataaga gtagtttact aaatactcat
     1921 cttcttcaaa ttgtatattt tgtagggtta gatgattatt ttttaattct gccgttattt
     1981 catacttgaa actatcatct atttttctaa atccaatatt tgaagttgat ttatccagta
     2041 tgtaatcatt aaagatttca taggataatt ccacttcata aaattgattt tcaaatattt
     2101 tgaatgggca gtatgatata aaacaatgta gttcataacc atttatttca atcaatactg
     2161 cctcttcaat ggtgttatct aactttttga ttttacattt atataacatt ttatcttgcc
     2221 tttagataaa ttgttttgtt ttttggattg ttattcaaag ttctccaaaa gtcttttcct
     2281 gattttgtat gtatcgtggt aacactacca ttttcattgg ttccaacaaa aataaattta
     2341 gattgacctt tggaatcagt acccaaaaac tgaacatatc cagacatgca gatttcgggt
     2401 tttaaatcaa atgcggctta ccggttttct tttttggttt ccgccggcgt gctgccgaaa
     2461 tattgcctga atgcctgagt aaagctggaa acgtggcggt agccgcataa atatgcggtt
     2521 tcgcctatgc ttttgccccc gttttgcaac agataaagcg cgtgctgcat ttgtttgtgg
     2581 tgcagccact cgcttgcggt aataccgaaa tggtcgcgca tacggcgttg cagcgtcctt
     2641 tcactgatgt tcagcgcgtc tgtcagccgg ttgacttggt gtgcgccgtc ggcaaacgcg
     2701 gcatttaggg tgcggctgaa gtcttcagac ggcatagcgt ctgcttccgc cgtttgcccc
     2761 gccgccggcc cgatgccgtc tgaaaccgtg tcccacaagt ccgacagcag ccgcaacacg
     2821 tccgcctcgc ggcgcaatgt ttcgcccaaa tgcccctttg ggacggcttt caggcaggat
     2881 gccgccaagc cgcgcaggtt cgggggcaaa tcccatatcc tgaccggttc gcggtaaagc
     2941 aggggtgcga aacgcgcgta ttccggacgc agcagccatt gttccatacc tttaatggtc
     3001 attttgaccg ttttgccgcc tcggtaaaga tagcggctga acaggacctc ttccccgaca
     3061 gcaattagga cgatcttgcc gccatccgca tcgatttgga agcggcggcg gttgatgccg
     3121 aagtccaaac tgccttccag caagagcacg aacgacacat aaggttcggc gaggcggctg
     3181 ctgcaaaaat cgcaccgtgc cgttaccgtg ccgccgtgga tggaaatgcc gttggacaaa
     3241 gtatcgaaac ggtagctgcc ctccacatag ctgccgccgc cgcttttgac cagattgacg
     3301 aaccggctgc tgttcaaatg ttctgctttt tccatagttt tctgataaag gttatcattt
     3361 gaaagataac atttttcgtc acagcaaaca atccgccgcc acaacggcat tttcacaaca
     3421 tttaccgtcc gtatgccgtc tgaaaattgc ccgtcttccc gataagcctt aaaatacacg
     3481 ccgtcaaacc taccgtccgt ccgtacatga gcccatcccc ctttatcgaa atgaaagacg
     3541 tcgccttcgc gtatggcgac cgcccgattc tgaagaacat caatttcagc attccgcaag
     3601 gcaattttgc tgccgtaatg ggcggttcgg gcagcggcaa aaccacgctg atgcgactga
     3661 ttacaggaca gattcgtccg cagtccgggc aggttttgat tgaaggacgg gatttggcgg
     3721 gcttttcggc tgacgagttg tatgaacacc gccgccgtat gggcgtattg ttccaacacg
     3781 gcgcgctgtt taccgatttg tctgtatttg acaatattgc ttttccgatg cgcgaactga
     3841 cgcgcctgcc ggaagcggtg attcgggatt tggttttgtt gaaattgaac gcggtcggtc
     3901 tgcgcggtgt ggaaaacctg atgccgtccg agttgtccgg cgggatgtcg cgccgcgtcg
     3961 cgcttgcccg cacgattgcg ctcgaccctg aaattatgtt gtacgacgag ccgtttaccg
     4021 gcctcgatcc gatttccttg ggcgtgattg cccacttgat cagccgcgtc aacaaggctt
     4081 tgcgttcgac cagtattatg gtaacgcacg acattgaaaa atctttggaa atcgtcgatc
     4141 aggtgatttt cttggcgcac ggcgaaatta tgttctccgg ctcgccgcag gaaatgcgcg
     4201 aactggattc gccttgggtg cgccagtttg tcggcgggct ggcagacggc cccgtagcat
     4261 accgttatcc ggcgcaaacg tcgttgcagc aggatttgct cgggtaaatt gagccggtgc
     4321 cgtctgaaac cgttgaactt tacatataga aatttatgaa ctttatccgt tccgtcgggg
     4381 cgaaaaccct cggccttatt caatccctcg gcagtatcac gctgtttctg ctgaacattc
     4441 tggcgaagtc cggtacggct ttcgtccgtc cgcgcctgag cgtgcgccaa gtgtatttcg
     4501 ccggcgtgct gtcggtgctg attgttgccg tttcggggct gttcgtcggt atggttttgg
     4561 gtttgcaggg ttatacgcag ttgtcgaaat tcaaatccgc cgatattttg ggctatatgg
     4621 tcgcggcttc gctgttgcgg gaactgggtc cggtgttggc ggcgatcctg tttgccagca
     4681 gcgcgggcgg tgcgatgacc agcgaaatcg gtctgatgaa aacgaccgaa cagctcgaag
     4741 cgatgaacgt gatggcggta aaccctgtcg cccgcgtggt tgcgccgcgc ttttgggcgg
     4801 gcgtgttttc catgccgctt ttggcttcga ttttcaacgt ggcgggtatt ttcggcgcgt
     4861 atttggtcgg tgtaacctgg ctgggcttgg acagcggcat tttctggtcg caaatgcaga
     4921 acaacatcac gatacattac gatgtaatca acggtctgat caaatccgcc gcgttcggcg
     4981 tggcggtaac gctgattgcc gtgcatcagg gcttccactg cgtcccgacc tcggaaggca
     5041 ttttgcgcgc cagcacgcgc acggtggttt cgtccgccct gacgattttg gcggtcgatt
     5101 ttatattgac cgcgtggatg tttacagatt gacagggcgt ctgaagacga aacgcggaac
     5161 atcggatatt caaggaactt taatgaaaaa gaacatattg gaattttggg tcggactgtt
     5221 cgtcctgatt ggcgcggcgg cggttgcctt tctcgctttc cgcgtggcgg gcggtgcggc
     5281 gttcggcggt tcggacaaaa cttacgccgt ttatgccgat ttcggcgaca tcggcggttt
     5341 gaaggtcaat gcccccgtca aatccgcagg cgtattggtc gggcgcgtcg gcgctatcgg
     5401 acttgacccg aaatcctatc aggcgagggt gcgcctcgat ttggacggca agtatcagtt
     5461 cagcagcgac gtttccgcgc aaatcctgac ttcgggactt ttgggcgagc agtacatcgg
     5521 gctgcagcag ggcggcgaca cggaaaacct tgctgccggc gacaccatct ccgtaaccag
     5581 ttctgcaatg gttctggaaa accttatcgg caaattcatg acgagttttg ccgagaaaaa
     5641 tgccgacggc ggcaatgcgg aaaaagccgc cgaataaacg tatgccatca tattcaaact
     5701 aggacactta atcatgaaaa aatcctccct catcagcgca ttgggcatcg gtattttgag
     5761 catcggcatg gcatttgccg cccctgccga cgcggtaaac caaatccgtc aaaacgccac
     5821 tcaagtattg agcatcttaa aaaacggcga tgccaacacc gcccgccaaa aagccgaagc
     5881 ctatgcgatt ccctatttcg atttccaacg tatgaccgca ttggcggtcg gcaacccttg
     5941 gcgcaccgcg tccgacgcgc aaaaacaagc gttggccaaa gaatttcaaa ccctgctgat
     6001 ccgcacctat tccggcacga tgctgaaatt aaaaaacgcc aacgtcaacg tcaaagacaa
     6061 tcccatcgtc aataaaggcg gcaaagaaat catcgtccgc gccgaagtcg gcgtacccgg
     6121 gcaaaaaccc gtcaacatgg acttcaccac ctaccaaagc ggcggtaaat accgtaccta
     6181 caacgtcgcc atcgaaggcg cgagcctggt taccgtgtac cgcaaccaat tcggcgaaat
     6241 tatcaaagcg aaaggcgtgg acggactgat tgccgagttg aaggctaaaa acggcagcaa
     6301 gtaatccata agccatgccg ccagactgaa ggcggcatgg atttttccct accgaacact
     6361 atgcatacag aactcaacaa cggaacactg cacatcagcg gcgacatcac cgtcaaaacc
     6421 ctgaccgccg ccgcttttac ccgcttcaga cagcaatgtc gtctgaaaga cacctgcgcg
     6481 gttgatttga gcggcgtcgg acgcgccgat tccgcctgcg tgtcgctgct gctcgaagtg
     6541 ctgcgcggtt gcaaaggcag cgtcaggctg accggcattc ccgaatccgt gcgcgcgctg
     6601 tccgaactgt acgaaatcaa agactggctg aaatcatgaa aaaaaccgcc tatgccttcc
     6661 tcctgctgat cgggttcgct tccgcccctg catttgccga aacccgcccc gccgaccctt
     6721 atgaaggcta caaccgcgcc gttttcaaat tcaacgacca agccgaccgc tacattttcg
     6781 cccctgccgc gcgcggctac cgcaaagttg cgccgaaacc cgtccgcgcc ggcgtgtcca
     6841 atttttttaa caacctgtgc gacgtggtca gcttcggcag caatatcttg cgcttggaca
     6901 tcaaacgcgc aagcgaagac cttgtccgcg tcggcatcaa caccactttc ggtttgggcg
     6961 ggcttatcga catcgccggc gcgggcggca ttcccgacaa taaaaacacc ttgggcgaca
     7021 cgtttgcctc gtggggatgg aaaaacagca attatttcgt gttgcccgtc ttagggccgt
     7081 ccaccgtccg cgacgcgctc ggcacgggta ttacctccgt ttattcgccc aagaatatcg
     7141 tcttccgcac ccctgtcgga cgctggggca cgactgccgt atccgccgtc agtacgcgcg
     7201 aaggcctgct cgatttgacc gacagtctgg acgaagccgc catcgacaaa tacagctaca
     7261 cgcgcgacct ctatatgaaa gtccgtgcgc ggcagaccgg tgcaacacct gccgaaggta
     7321 cggaagataa catcgacatc gacgaattgg tcgaaagtgc cgaaaccggc gcggcggaaa
     7381 ctgccgttca agaagattcc gtatccgaaa cacaggcaga agcagcaggg gaagccgaaa
     7441 cgcaacctgg aacacaacct taaagccatg ccgtctgaaa atccgtgttc ggacggcatt
     7501 cccttctgtc ggaacggaca gtccgaaacc acagattggg ctataatctc ttttttgcgc
     7561 ataccgcgcg acagcaaagg aaaaaccatg tacgaagtca accgcagcgt attcgtcctc
     7621 atccctttag aacctttttg gaactggctg caaaccctgc cgggcaacca cctcgacgga
     7681 ctgactcttg aagacatcca agccgacgcc aattcctacc ttgtccgccc gtgcgaaacc
     7741 gccgacgaag tatgggacga aatcgaagcc cgttttgaag acattttcgc cgccgaactt
     7801 gccgactggt gcgaagacga acgcgagtgg cctgcgctcg atgccgacat tttcaacgaa
     7861 tggttcgaca tccagctttc taccgtcatc accgacctcg aacacgaacc gcttgcccgc
     7921 gaagccttcc aacccatcaa cctgaactga tgaagctgac cgtccgcaac taccatctcg
     7981 acggctacgg ccatgtcaac aatgcgcgct acctcgaatt tttcgaagaa gcgcgctggg
     8041 cgttttttga agaacgcgga ctgctgcacg agttggcagg cctcatactg attgtcgccc
     8101 gcatcgacat ccgatacagc cgccccgccg tcgaaggcga cgtattgcag ttttcatgcc
     8161 gcctgaaaac ccccggcacg cgccgtattg tgctgaccca gacgattaca ctgccaaacg
     8221 gcaaaaccgc cgcagaagcc gacatcaccc tgatgcccgt ccacgccgcc acacaacgca
     8281 ccgtcagcct gcccgccacc cttgcccgcg cattggaagc cttgtccgaa tgaaaaaaat
     8341 actcaccgcc gccgtcgtcg cactgatcgg catcctcctt gccatcgtcc tcatccccga
     8401 cagcaaaacc gcgcccgcct tctccctgcc cgacctgcac ggaaaaaccg tttccaacgc
     8461 cgacctgcaa ggcaaagtaa ccctgattaa tttttggttt ccctcctgtc cgggttgtgt
     8521 gagcgaaatg cccaaaatca ttaaaatggc aaattactat aaaaacaaaa acttccaagt
     8581 ccttgccgtt gcacaaccta tcgatccgat agaaagcgtc cgccaatatg tcaaagacta
     8641 cggtttgccg tttaccgtca tgtatgatgc ggacaaagct gtcggacagg cgttcggcac
     8701 acaggtttat ccgacttccg tccttatcgg caaaaaaggc gaaatcctca aaacttatgt
     8761 cggcgaaccc gatttcggca aactctacca agaaatcgat accgcgctgg cacaatagcg
     8821 atgccgtctg aagcgcaaaa aaaacagaaa cgatgttcct gttttttcag atcatccgcc
     8881 ccgacacgtt cagacggcat tcaaccttcc ggcagattct ttttcaccac tgccggattg
     8941 cctgccgcca aagagtaggg cggaatgtct tttgtaacca ccgcgcctgc gcccacgacc
     9001 gaaccgcgtc cgacggttac gcccgccatt acaatcaccc tgtgccccgg ccagacatcg
     9061 tcctccaacg taatcggacg gatttccgtg tagccctcaa agcgtttttt gaacggtcaa
     9121 acttgtggtt atttgaataa aacagacatt ccggctccat catcacattt ttgccgacca
     9181 ccagcccacg gcagatttca cagtttgccc cgatgcccga gccgtcgccc aaaaccgtat
     9241 ccggaaacac atacgccccg cgttcgatat tgaccccgcg tccgatatgc ggagaaaccc
     9301 gccgcgccaa aaaaccgcgc acccgtctgc cgacgatgcc gatgccgcgc atatgtgacg
     9361 gcggcaaccc cgaaccggca aaacgcagca gcaggaaaaa gaattttgat cccatcaaac
     9421 ctccctcaaa agaacttttt atagtggatt aacaaaaatc aggacaaggc gacgaagccg
     9481 cagacagtac agatagtacg gcaaggcgag gcaacgctgt actggttttt gttaatccac
     9541 tatacatttt atcgaatatc ctcttgacga aacaacagaa aatagcgaga atgccgagct
     9601 tgtctgaagc ataggtacat cccctatgcc cgcttttttg aaaggaaatc aaatgaaaca
     9661 aggtattcac ccgaactacc acgaagtcaa cgttacctgc tcttgcggca acaaattcgc
     9721 aaccaaatcc gcgatggaaa aagaaaactt caatatcgag gtttgctccc tgtgccaccc
     9781 gttctatacc ggcacccaaa aaatcgtcga taccaccggc cgcgtggaca aattcaacaa
     9841 caaattcggc aacctgttca aacgctgatt gccgttttgc aagaattaag ccctgccatc
     9901 atttcgatgg cagggctttt taatatttgg cacactgact tcttatc
//
LOCUS       DAXIDM010000066         9864 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000066 DAXIDM010000000
VERSION     DAXIDM010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9864
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.066"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            131..1300
                     /gene="prpF"
                     /locus_tag="ACFOAE_001415"
     CDS             131..1300
                     /gene="prpF"
                     /locus_tag="ACFOAE_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004464330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylaconitate cis-trans isomerase PrpF"
                     /protein_id="HFC6884883.1"
                     /translation="MPQIKIPAVYYRGGTSKGVFFKRSDLPEAAREAGSARDKILLRV
                     LGSPDPYGKQIDGLGNASSSTSKAVILDKSERADHDVDYLFGQVSIDKPFVDWSGNCG
                     NLTAAVGAFAIEQGLVDKGKIPSDGICTVKIWQKNIGKTIIAHVPMQNGAVLETGDFE
                     LDGVTFPAAEVQIEFLDPADGEGSMFPTGNLVDEIDVPNIGRLKATLINAGIPTVFLN
                     AADLGYTGKELQDDINNDAAALEKFEKIRAYGALKMGLISDVSEAAARAHTPKVAFVA
                     PAADYTASSGKTVNAADIDLLVRALSMGKLHHAMMGTASVAIATAAAVPGTLVNLAAG
                     GGTRKEVRFGHPSGTLRVGAAAECQDGQWTATKAVMSRSARVMMEGWVRVPEDCF"
     gene            1715..2914
                     /locus_tag="ACFOAE_001416"
     CDS             1715..2914
                     /locus_tag="ACFOAE_001416"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFC6884884.1"
                     /translation="MSDQLILVLNCGSSSLKGAVIDRKSGSVVLSCLGERLTTPEAVI
                     TFNKDGNKRQVPLSGRNCHAGAVGMLLNELEKHGLHDRIKAIGHRIAHGGEKYSESVL
                     IDQAVMDELNACIPLAPLHNPANISGILAAQEHFPGLPNVGVMDTSFHQTMPERAYTY
                     AVPRELRKKYAFRRYGFHGTSMRYVAPEAARILGKPLEDIRMIIAHLGNGASITAIKN
                     GKSVDTSMGFTPIEGLVMGTRCGDIDPGVYSYLTSHAGMDVAQVDEMLNKKSGLLGIS
                     ELSNDCRTLEIAADEGHEGARLALEVMTYRLAKYIASMAVGCGGVDALVFTGGIGENS
                     RNIRAKTVSYLDFLGLHIDTKANMEKRYGNSGIISPTDSSPAVLVVPTNEELMIACDT
                     AELAGIL"
     gene            3022..3642
                     /locus_tag="ACFOAE_001417"
     CDS             3022..3642
                     /locus_tag="ACFOAE_001417"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFC6884885.1"
                     /translation="MAQFFAVHPDNPQERLIKQAVEIVNKGGVVVYPTDSCYALGCKL
                     GDKAAMERILSIRKIDLKHHLTLMCADLSELGTYAKVDNVQFRQLKAATPGPYTFILQ
                     ATKDVPARTLHPKRKTIGLRIPDNAIAQALLGELGEPLLSCTLMLPEDGEPLTDPYEI
                     RERLEHAVDLVIDGGWCGTEPTTVVDMTDGTELVRQGCGDTAVFGL"
     gene            complement(3804..4247)
                     /locus_tag="ACFOAE_001418"
     CDS             complement(3804..4247)
                     /locus_tag="ACFOAE_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFC6884886.1"
                     /translation="MYLTQHTDYGLRVLIYTAINDDALVNISTIAVTYGISKSHLMKV
                     VTALVKGGFLHSVRGKGGGLRLAAPPDRINIGSVVRHLEPMQLVECMGSNNECLITPS
                     CRLTGILGGAMKSFFTYLDGFTLQDLLNKPTYDLLYEPRIPIAVQ"
     gene            4421..4789
                     /locus_tag="ACFOAE_001419"
     CDS             4421..4789
                     /locus_tag="ACFOAE_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemerythrin domain-containing protein"
                     /protein_id="HFC6884887.1"
                     /translation="MKPLKRHPALIGLSRDHHHSLSLCVRLLRTPEERHRDELEPHFS
                     ELETHFREEEAKFAPIWQNVAPELKQRFEKDHARLRQMMASPEYGNAAWNTAFATTLR
                     DHARFEERELFPAAEPFLPA"
     gene            4834..5988
                     /locus_tag="ACFOAE_001420"
     CDS             4834..5988
                     /locus_tag="ACFOAE_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NnrS family protein"
                     /protein_id="HFC6884888.1"
                     /translation="MKFTKHPVWAMAFRPFYSLAALYGALSVLLWGFGYTGTHELSGF
                     YWHAHEMIWGYAGLVVVAFLLTAVATWTGQPPTRGGVLVGLTIFWLAARIVAFIPGWG
                     ASASGILGTLFFWYGAVCMALPVIRSQNQRNYVAVFALFVLGGTHAAFHVQLHNGNLG
                     GLLSGLQSGLVMVSGFIGLIGTRIISFFTSKRLNVPQIPSPKWVAQASLWLPMLTAML
                     MAHGVMPWLSAAFAFAAGVIFTVQVYRWWYKPVLKEPMLWILFAGYLFTGLGLIAVGA
                     SYFKPAFLNLGVHLIGVGGIGVLTLGMMARTALGHTGNPIYPPPKAVPVAFWLMMAAT
                     AVRMVAVFSSGTAYTHSIRTSSVLFALALLVYAWKYIPWLIRPRSDGRPG"
     gene            complement(6045..6917)
                     /locus_tag="ACFOAE_001421"
     CDS             complement(6045..6917)
                     /locus_tag="ACFOAE_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003695549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFC6884889.1"
                     /translation="MPILNHIALIGVGLIGGSFVLDLKRQGLVRTVTGIDTDRDNLER
                     ALERGVIDRASVAIDADSIGGADLVLIATPVATVPAILTALRPVLPEHTWISDVGSTK
                     SSVIEAFRRCLPDRLHRCIAAHPIAGSDRSGAQAAQFGLFRHRKLIITPHGGEHSDGI
                     ALVEELWHAVGAEIYTMDAQRHDAVFAAVSHMPHLTAFAYVHQILDHPDGQEYLKFAA
                     TGFRDFTRIASGHPAVWADICLANKDSLLQLVQGLGKQLDVLANILTTDDREALYRYF
                     KEAKTTRDRWLDGN"
     gene            7002..7814
                     /locus_tag="ACFOAE_001422"
     CDS             7002..7814
                     /locus_tag="ACFOAE_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HFC6884890.1"
                     /translation="MDKIRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEY
                     WVLMGANDTDKLALAEPLGGGRFQTALSETAKECGVVLFGGTVPLQSPEAGKVMNTLL
                     VYGRDGKRTGLYHKMHLFGFSGLGERYAEADTIRAGGEVPHLSAEGVSVAAGICYDVR
                     FPEFFRRQLPFDVLMLPAAFTHTTGKAHWELLLRARAVENQCYVVAAAQGGLHENGRR
                     TFGHSMIVDPWGDVLDVLPEGEGVVTADIDANRLNSVRNRLPALKYRVLDAV"
     gene            complement(8977..9780)
                     /locus_tag="ACFOAE_001423"
     CDS             complement(8977..9780)
                     /locus_tag="ACFOAE_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC6884891.1"
                     /translation="MQPPKNLLFSSLLFSSLLFSSAAQAASEDSSRSPYYVQADLAYA
                     AERITHDYPKPTGTDKDKISTVSDYFRNIRAHSIHPRVSVGYDFGGWRIAADYASYRK
                     WNNNKYSVNTKEVERNNTSGNWKELKTENQENGTFHASSSLGLSAIYDFKLNDKFDKF
                     KPYIGVRVAYGHVKHQVHSVRKETTTAFLKPSKGATEPGKIPSLVTKPAYHESHSTSS
                     LGLGVIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGMRYHF"
BASE COUNT         2135 a         2631 c         2864 g         2234 t
ORIGIN      
        1 acaacacagt agccgtagat tggggcgaac cccgacagtt tgcggaatca aacggctttg
       61 gtcggagtgg cagcctaatc cactataaaa atcgtgggca gagcccacgc tacataagga
      121 gaatctagaa atgccgcaaa ttaaaattcc cgccgtttac taccgtggcg gtacatcaaa
      181 aggcgtgttt ttcaaacgtt ccgacctgcc cgaggcggcg cgggaagcgg gaagcgcacg
      241 cgacaaaatc ctcttgcgcg tactcggcag cccggatccc tacggcaagc agatagacgg
      301 tttgggcaac gccagctcgt ccaccagcaa ggcggtgatt ttggacaagt ccgaacgcgc
      361 cgatcacgat gtcgattacc ttttcgggca agtttccatc gacaaacctt ttgtcgattg
      421 gagtggcaac tgcggcaacc tcaccgccgc cgtgggcgca tttgccatcg agcaaggctt
      481 ggtcgataaa ggcaagattc cttcagacgg catctgcacg gtcaaaatct ggcagaaaaa
      541 catcggcaaa accattattg cccatgtacc gatgcaaaac ggcgcagttt tggaaacagg
      601 cgattttgag ctcgacggcg taacgttccc ggcagccgaa gtacaaatcg aatttcttga
      661 tccagccgac ggtgaaggca gtatgttccc aaccggcaat ttggtcgatg aaattgatgt
      721 gccgaatata ggccgtttga aagccacgct catcaacgcg ggcattccga ccgttttcct
      781 gaatgccgcc gacttgggct acacgggcaa agagttgcaa gacgacatca acaacgatgc
      841 cgcggctttg gaaaaattcg agaaaatccg cgcttacggt gcgctgaaaa tgggtctgat
      901 cagcgacgta tccgaagctg ccgctcgcgc gcacacgccg aaagtcgcct tcgtcgcgcc
      961 cgccgccgat tacaccgcct ccagtggcaa aaccgtgaac gccgccgaca tcgatttgct
     1021 ggtacgcgcc ctgagcatgg gcaaattgca ccacgcgatg atgggtaccg cctctgttgc
     1081 cattgcgacc gccgccgccg tgcccggtac gctggtcaac cttgccgcag gcggcggaac
     1141 gcgtaaagaa gtgcgcttcg ggcatccttc cggcacattg cgcgtcggtg cagccgccga
     1201 atgtcaggac ggacaatgga cggccaccaa agcggttatg agccgcagcg cacgcgtgat
     1261 gatggaaggt tgggtcaggg tgccggaaga ttgtttttaa attgacgtag catgggtttg
     1321 cccgcgagcc ataaacaggt cgtctgaaaa acaagtaaac atcaaatcac tgaccattcc
     1381 tttcccttgc cctgtggcgg aaggcggcaa atcacaagga agaacacgga aaccccgata
     1441 aaagacagct tcccgtatta ccgtcattcc cgcgcaggcg ggaatctaga cctgtcaata
     1501 tggaggattg gtaggggaaa acaggtttcg tgagttctac attctggatt cccgccacag
     1561 cctgtcctcg cgtaggcggg gacggaataa cgatagaaaa tgcggcatac gctttgccca
     1621 aagaggccgt ctgaaacacc ttgcgcctga tgtctgcctt tttcagacga ccccacacca
     1681 aaaaaaacaa ccacaaacta caaggagaaa catcatgtcc gaccaactca tcctcgttct
     1741 gaactgcggc agttcatcgc tcaaaggcgc cgttatcgac cgaaaaagcg gcagcgtcgt
     1801 cctaagctgc ctcggcgaac gcctgaccac gcccgaagcc gtcattacgt tcaacaaaga
     1861 cggcaacaaa cgccaagttc ccctgagcgg ccgaaattgc cacgccggcg cggtgggtat
     1921 gcttttgaac gaactggaaa aacacggtct gcacgaccgc atcaaagcca tcggccaccg
     1981 catcgcccac ggcggcgaaa aatacagcga gtctgttttg atcgaccagg ccgtaatgga
     2041 cgaactcaat gcctgcattc cgcttgcgcc gctgcacaac cccgccaaca tcagcggcat
     2101 ccttgccgca caggaacatt tccccggtct gcccaatgtc ggcgtgatgg atacttcgtt
     2161 ccaccaaacc atgccggagc gtgcctacac ttatgccgtg ccgcgcgagt tgcgtaaaaa
     2221 atacgctttc cgccgctacg gtttccacgg caccagtatg cgttacgttg cccctgaagc
     2281 cgcacgcatc ttgggcaaac ctctggaaga catccgcatg attattgccc acttaggcaa
     2341 cggcgcatcc attaccgcca tcaaaaacgg caaatccgtc gataccagta tgggtttcac
     2401 gccgatcgaa ggtttggtaa tgggtacacg ttgcggcgac atcgatccgg gcgtatacag
     2461 ctatctgact tcccacgccg ggatggatgt tgcccaagtg gatgaaatgc tgaacaaaaa
     2521 atcaggtttg ctcggtattt ccgaactttc caacgactgc cgcaccctcg aaatcgccgc
     2581 cgacgaaggc cacgaaggcg cgcgcctcgc cctcgaagtc atgacctacc gcctcgccaa
     2641 atacatcgct tcgatggctg tgggctgcgg cggcgttgac gcactcgtgt tcaccggcgg
     2701 tatcggcgaa aactcgcgta atatccgtgc caaaaccgtt tcctatcttg atttcttggg
     2761 tctgcacatc gacaccaaag ccaatatgga aaaacgctac ggcaattcgg gcattatcag
     2821 cccgaccgat tcttctccgg ctgttttggt tgtcccgacc aatgaagaac tgatgattgc
     2881 ctgcgacact gccgaacttg ccggcatctt gtagccaaaa aagggacgag tccgcaaaaa
     2941 tgccgtctga aattttcaga cggcattttg tttggcgttt gggcgtacaa tacggaaaac
     3001 atgacgataa ggaaacaaac catggcacag tttttcgccg ttcatcccga caacccccaa
     3061 gaacgcctca tcaagcaggc ggtcgaaatc gtcaataaag gcggcgtggt cgtttatccg
     3121 accgattcct gttatgcctt gggctgcaaa ctcggcgata aggcggcgat ggaacgcata
     3181 ctctccatcc gcaaaatcga tttgaaacac cacctgaccc tgatgtgcgc agatttgagc
     3241 gagttgggca catacgccaa agtcgacaac gtacagtttc gtcagcttaa agccgccaca
     3301 cccgggcctt atacttttat tttacaggcg acgaaggatg tgccggcgcg cacgctgcac
     3361 ccgaaacgca aaaccatcgg gctgcgtatt cccgataatg ccattgcaca agccctgctg
     3421 ggggaattgg gcgagccgct tttaagctgc accctgatgc tgcccgaaga cggcgaacca
     3481 ttgaccgatc cttatgaaat ccgcgagcgt ttggaacacg ccgtcgattt ggtgattgac
     3541 ggcggctggt gcggaaccga gccgaccacc gtcgtcgata tgaccgacgg cacggaattg
     3601 gtgcgccaag gttgcggcga tacggcggtg ttcggtttgt agggaaaccg atgccgtctg
     3661 aagcatcggc tgttcagacg gcattgcgcg ccttgccggc ggcagtccga aatgccggcg
     3721 cgtatcgcgc tcggtcggaa tatccgtttg aaacggcaaa caaaatgccg tccgaacgcg
     3781 ggttcggacg gcattttgat gcattactgc accgcaatcg gaattctcgg ttcgtagagc
     3841 aggtcgtagg tcggcttgtt gagcaggtct tggagcgtga aaccgtccag atacgtgaaa
     3901 aacgacttca tcgcgccgcc gagtatgccc gtcagccggc aggacggtgt aatcaggcat
     3961 tcgttgttcg aacccataca ttcgaccagc tgcatcggtt cgaggtggcg gacaaccgag
     4021 ccgatgttga tgcggtcggg cggtgcggca agccgcagac cgccgccttt tccgcgcaca
     4081 ctgtggagga agccgccttt gaccagcgcg gtaacgacct tcatcagatg gcttttggaa
     4141 atgccgtagg ttacggcgat ggtactgatg ttgaccagcg catcgtcgtt gatggcagtg
     4201 tagataagga cgcgcagccc gtagtccgta tgttgtgtca aatacatgat tttctcggta
     4261 tggattgtta ttcttatcgg tacggtttaa ggttcacgga caatacctta atggttgaaa
     4321 ccctgtccgt cggggcggta gaatgcagcc tgtctgcggc ggtatgctgt ctgaaacatc
     4381 cgcgctaccg tttgagaatt tgttattgta actcaaaatc atgaaaccgt tgaaacgaca
     4441 tcccgccctt atcgggcttt cgcgtgacca ccaccattcg ctttccctgt gcgtgcgtct
     4501 gttgcggacg ccggaagaaa ggcatcggga cgaactcgaa ccgcattttt ccgaattgga
     4561 aacccatttt cgcgaagaag aagccaagtt tgccccaatt tggcagaatg tcgcccccga
     4621 attgaaacaa cgtttcgaga aagaccacgc ccgactgcgg cagatgatgg caagccccga
     4681 atacggtaac gcggcgtgga ataccgcttt tgccacaacc ctgcgcgacc acgcgcgctt
     4741 tgaagaacgc gagctgtttc ccgccgccga accgtttttg ccggcatgat tccgttttgc
     4801 ggcaaatata ttaatgataa acaaggaaca cacatgaaat ttaccaagca ccccgtctgg
     4861 gcaatggcgt tccgcccatt ttattcgctg gcggctctgt acggcgcatt gtccgtattg
     4921 ctgtggggtt tcggctacac gggaacgcat gagctgtccg gtttctattg gcacgcgcat
     4981 gagatgattt ggggttatgc cggactggtc gtcgtcgcct tcctgctgac cgccgtcgcc
     5041 acttggacgg ggcagccgcc cacgcggggc ggcgttctgg tcggcttgac tatcttttgg
     5101 ctggctgcgc ggattgtcgc ctttatcccg ggttggggtg cgtcggcaag cggcatactc
     5161 ggtacgctgt ttttctggta cggcgcggtg tgcatggctt tgcccgttat ccgttcgcag
     5221 aatcaacgca actatgttgc cgtgttcgcg ctgttcgtct tgggcggtac gcacgcggcg
     5281 ttccacgtcc agctgcacaa cggcaactta ggcggactct tgagcggatt gcagtcgggc
     5341 ttggtgatgg tgtcgggttt tatcggtctg attggtacgc ggattatttc gttttttacg
     5401 tccaaacggt tgaatgtgcc gcagattccc agtccgaaat gggtggcgca ggcttcgctg
     5461 tggctgccca tgctgaccgc catgctgatg gcgcacggcg tgatgccttg gctgtcggcg
     5521 gctttcgcgt ttgcggcagg tgtgattttt accgtgcagg tgtaccgctg gtggtataaa
     5581 cccgtgttga aagagccgat gctgtggatt ctgtttgccg gctatctgtt taccggattg
     5641 gggctgattg cggtcggcgc gtcttatttc aaacccgctt tcctcaatct gggtgtgcat
     5701 ctgatcgggg tcggcggtat cggcgtgctg actttgggca tgatggcgcg taccgcgctc
     5761 ggtcatacgg gcaatccgat ttatccgccg cccaaagccg ttcccgttgc gttttggctg
     5821 atgatggcgg caaccgccgt ccgtatggtt gccgtatttt cttccggcac tgcctacacg
     5881 cacagcatac gcacctcttc ggttttgttt gcactcgcgc ttttggtgta tgcgtggaag
     5941 tatattcctt ggctgattcg tccgcgttcg gacggcaggc ccggttgaga caaaccgccg
     6001 cagatttcgg gtctgggcgg tttgcttttc agacggcagg gcggtcagtt gccgtccagc
     6061 cagcggtcgc gtgtggtttt ggcttcttta aaatagcggt acagggcttc gcggtcgtcg
     6121 gtggtcagga tgtttgccaa aacgtccaac tgtttgccca agccttgaac cagttgcagc
     6181 aggctgtctt tgttggcaag gcagatgtcc gcccacacgg cgggatgacc ggaggcgatg
     6241 cgggtgaagt cccgaaagcc cgtggcggcg aatttcagat attcctgtcc gtcggggtgg
     6301 tcgagaatct ggtggacata ggcgaaggcg gtcaggtggg gcatatggga gacggcggcg
     6361 aaaaccgcgt cgtggcgttg cgcgtccatc gtataaattt ccgcaccgac cgcgtgccac
     6421 agttcttcta ccaaggcaat gccgtctgaa tgttcgccgc cgtgtggcgt gatgatgagt
     6481 tttctgtggc ggaacagccc gaactgcgcg gcttgcgcac cgcttctgtc cgaaccggca
     6541 atcgggtggg cggcgatgca gcggtgcagg cggtcgggca gacagcggcg gaaggcttcg
     6601 atgaccgaag atttggtgct gccgacatcg gaaatccaag tgtgttccgg caaaacgggg
     6661 cgcagcgcgg tcaaaatggc gggaacggtg gcgacgggcg tggcaatcag taccaagtcc
     6721 gcaccgccga tgctgtccgc gtcgatggca acggacgcac ggtcaatcac gccgcgttcc
     6781 aatgcacgtt cgaggttgtc gcggtcggtg tcgataccgg taacggtgcg gacgagtccc
     6841 tgccttttga ggtcgagaac gaacgaaccg ccgatcagcc ctacaccgat gagggcaata
     6901 tggttcaaaa tgggcatttg tgtaaacggt tttcgcaaag taccgtcatg gtagcctatc
     6961 ggcggaatat gccgcaaggt cggcaggaaa aaggagaaga aatggacaaa atcagagttg
     7021 ccgccgtgca gatggtgtcg ggcgtgtcgc cggaaaccaa cgtcgctgcc atgaaacgcc
     7081 tggtcgcacg ggcggcggag cagggggcgg attgggtgct gctgcccgaa tattgggtgc
     7141 tgatgggcgc aaacgatacc gacaaactcg cgcttgccga gcctttgggc ggcggacgct
     7201 ttcagacggc attgagcgaa acggcgaaag aatgcggcgt ggtgctgttt ggcggaaccg
     7261 tgccgctgca aagccccgag gcgggcaagg tcatgaatac tttattggtg tacgggcgcg
     7321 acggcaaacg gacggggctg taccacaaaa tgcacctctt cggcttttcc ggtttgggcg
     7381 aacgctatgc cgaagccgat accatccgcg cgggcgggga agtgccgcac ttgtcggcag
     7441 aaggcgtgtc ggtggcggcg ggcatttgtt acgatgtccg ctttcccgaa tttttccgcc
     7501 gccagctgcc gtttgacgta ttgatgctgc ccgctgcgtt tacgcacacg acgggcaagg
     7561 cgcattggga gctgctgctg cgcgcgcgtg ccgtcgaaaa ccaatgttac gtcgtggcgg
     7621 cggcacaggg cggtttgcac gaaaacggac ggcgcacgtt cggacacagc atgattgtcg
     7681 atccgtgggg cgacgtgttg gacgtattgc ccgaaggcga aggcgttgtt acggcagaca
     7741 tcgatgccaa tcgcctgaac agcgtccgca accgcctgcc cgccttgaaa taccgggttt
     7801 tggatgccgt ctgaaggttc agacggcatc ggtgccgggg aatcagcggg ctgtaggatg
     7861 ggcttcagcc tgccatttcc atcaatccca catttctacc gttttcatcg aatccatcga
     7921 atccgcccct ttcgacgacc cagtcctacg caactgaacc gtcattccca cggaagtggg
     7981 aatctagaat ctcggggttt cagtcatttc cgatagattc ccgccgcgtc aggggtctgg
     8041 attcccgctt gcgcgggaat gacgaatcca tccatacgga aacctgtacc acgtcattcc
     8101 cacgaaagtg ggaatctaga atctcggggg tttcagtcat ttccgataga ttcccgccgc
     8161 gtcggaggtc tggattcccg cctgcgcggg aatgacgggt tttaagattg cggtattgtc
     8221 aggaatgacg aatccatcca tacggaaacc tgcaccacgt cattcccacg gaagtgggaa
     8281 tctagaatct cggggtttca gtcatttccg atagattccc gccgcgtcgg gggtctggat
     8341 tcccgcctgc gcgggaatga cgaatttcga gattacggtg ttgtcggaac gaaactgaat
     8401 cgtcattccc acgaaagtgg gaatctagaa cgcggggttt gggcaactgt ttttatccga
     8461 taagtttctg tgcggacagg tctggattcc cgcctgcgcg ggaatggcgg gtttcaagat
     8521 tgcggtgttg tcggaacgca actgaatcgt cattcccacg gaagtgggaa tctagaatct
     8581 cgaggtttca gtcatttccg atagattccc gccgcgtcag gggtctggat tcccgcctgc
     8641 gcgggaatga cgaatttcga gattgcggtg ttgtcgggaa tgacgaatcc atccatacgg
     8701 aaacctgcac cacgtcattc ccacggaagt gggaatctag aatctcgggg gtttcagtca
     8761 tttccgatag attcccaccg cgtcaggggg ctggattccc gcctgcgcgg gaatgacgaa
     8821 tttcgagatt gcggtgttgt cgggaatgac aaatttcaag attacggtgt tgtcgggaat
     8881 gacggttcgg gtatttccac gcccgccccg cgcctgtaaa cggcgagtgc atcaaaaatg
     8941 ccgtctgaag gttcagacgg catcggtgtc ggggaatcag aagtggtagc gcatgcccaa
     9001 tgagacttcg tgggttttga agcgggtgtt ttccaagcgt ccccagttgt ggtaacggta
     9061 tccggtgtcc aaggtcagct tgggcgtgat gtcgaaaccg acaccggcga tgacaccaag
     9121 acccaagctg ctggtgctgt ggctttcgtg ataggcaggt ttggtaacca aacttgggat
     9181 cttgcctggc tctgtagcac ctttcgatgg tttaaggaaa gcagtcgtgg tttcttttct
     9241 cactgaatga acctgatgtt taacgtgtcc gtaggcgacg cgcacaccga tatagggttt
     9301 gaatttatcg aatttatcgt tgagtttgaa atcgtaaatg gcggataagc cgagagaaga
     9361 agaggcgtgg aatgtaccgt tttcctgatt ttccgtcttc agttctttcc agttgccact
     9421 ggtattgttt ctttccacct cttttgtgtt gacggaatat ttattgttgt tccattttct
     9481 gtaactggca taatctgccg ctatcctcca gccgccgaaa tcatagccga ccgacacccg
     9541 ggggtggatg gaatgcgcac ggatgtttct gaaataatcg cttaccgtgc ttattttgtc
     9601 tttgtctgta ccggttggtt tcggataatc gtgggtaatg cgttcggcgg cataggctaa
     9661 atccgcctgc acataatacg ggctgcggct gctgtcttca cttgccgcct gcgctgcgga
     9721 agagaagaga agagaagaga agagaagaga agagaagaga aggttttttg ggggctggat
     9781 tcattttcgg ctccgtattc ggttttaact gattaaaaag aacaattttc aatgatgttg
     9841 caggagcgga ctatatcagg tttg
//
LOCUS       DAXIDM010000067         9795 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000067 DAXIDM010000000
VERSION     DAXIDM010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9795
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.067"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(11..1306)
                     /locus_tag="ACFOAE_001424"
     CDS             complement(11..1306)
                     /locus_tag="ACFOAE_001424"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFC6884892.1"
                     /translation="MIRPDFQEYLPSYYFSSVNPHTVYPKLQCRLKTDTCIIGGGLSG
                     LCTALPLAEQGHETVVLEAARIGFGASGRSGGQVISDYACGMGEIEKQVGLEQAQWFW
                     QQSLQAVELVDERVRKHAIDCDWQRGYATVAVRPQHWEELQQWHEHAQRHYGASHYQL
                     WDNTELKQQLDSDMYQGAQFDPLSGHLHPLNYTLGIARAAAEAGAQIFEQSPMTRIEP
                     HQNGWLVYTPEGSVECKNLVYAVNTYAGLNPIFKPLERKAIAVSTFIIATEPLGARAK
                     GLIRNNMAVCDNRHILDYYRLSADGRLLFGGKDNEFIDNPARMTELVRQDMLKVFPQL
                     ADVKIEYSWGGECDITANLVPHFGRLAPNVFYTQGYSGHGMAITGIAGLAVAEAILGD
                     ECRLKPFERLRQPNIILQPFLRKLGSFLGSKYYQWKDSR"
     gene            complement(1432..2319)
                     /locus_tag="ACFOAE_001425"
     CDS             complement(1432..2319)
                     /locus_tag="ACFOAE_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003675707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFC6884893.1"
                     /translation="MQKSKLSWFLKLMLALSLAFLYIPLVVLVIYSFNESKLVTVWGG
                     FSTKWYGALLENDTILEAAWLSLRIAVVSSLAAVVLGTLAGYAMARIKRFRGSTLFAG
                     MISAPMVMPDVITGLSMLLLIIQVQIFLQGSEWLQHLYFDRGFFTIFLGHTTLCMAYI
                     TVVIRSRLVELDQSLEEAAMDLGARPLKIFFVITLPLIAPAIASGFLLGITLSLDDLV
                     ITSFLSGPGSSTLPQVIFSKIKLGLDPQMNVLATILIGIIGTLVIIVNYWMMRQATKR
                     DREAAEAYRQEKLAAEKAN"
     gene            complement(2319..3284)
                     /locus_tag="ACFOAE_001426"
     CDS             complement(2319..3284)
                     /locus_tag="ACFOAE_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFC6884894.1"
                     /translation="MNLNKLKNKLFRRPGQRAVIAVPYIWLLVLFLIPFAIVLKISFA
                     EQEIAIPPFTPLTTIDEDLGRLNIAVSYQNYADIFQNFWSTLNPFGDGENSNIYLMTY
                     WSSIKTALTTTVICLLVGYPTAYAISRANPSVRNGLLLAIMLPFWTSFLLRVYAWMGL
                     LGHNGIVNNLLIKMGIISEPLDLFYNAFSLNLVMVYAYLPFMILPLYTQLVKLDNRLL
                     EAASDLGAGPVKSFLTITLPLSKTGIIAGSMLVFVPAVGEFVIPELVGGSENLMIGKV
                     LWQAFFDQNNWPLASAVAVVMVALLVVPIALFQHYENRELEEGAK"
     gene            complement(3300..4424)
                     /gene="potA"
                     /locus_tag="ACFOAE_001427"
     CDS             complement(3300..4424)
                     /gene="potA"
                     /locus_tag="ACFOAE_001427"
                     /EC_number="7.6.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015417 - ABC-type polyamine transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter ATP-binding protein"
                     /protein_id="HFC6884895.1"
                     /translation="MTATTASSTKPYLQIQGLVKKFGDNYAVDNIDLDIYQHEIFALL
                     GSSGSGKSTLLRMLAGMENPNQGKIILDGQDITKLAPYDRPINMMFQSYALFPHMTVE
                     QNIAFGLKQDKMPKGEIAARVEEMLRLVQMTKFAKRKPHQLSGGQQQRIALARSLAKR
                     PKILLLDEPLGALDKKLRQQTQLELVNTLEQVGVTCIMVTHDQEEAMTMATRIAIMSD
                     GQLQQVGTPSDVYDYPNSRFTAEFIGETNIFDGVVIEDHADYAVIECEGLENHVRIDH
                     GLGGPSEQDLWVSIRPEDIDLYKEKPEYLGDYNWAKGTVKEIAYLGSFAIYHIKLGNG
                     RVVKSQVPAPYWYVRNITPPTWDETVYISWPENQPTPLFR"
     gene            complement(4619..4726)
                     /locus_tag="ACFOAE_001428"
                     /pseudo
     CDS             complement(4619..4726)
                     /locus_tag="ACFOAE_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(4805..5074)
                     /gene="rpsO"
                     /locus_tag="ACFOAE_001429"
     CDS             complement(4805..5074)
                     /gene="rpsO"
                     /locus_tag="ACFOAE_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019958878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFC6884896.1"
                     /translation="MALTVEQKAQIVKDFQRKEGDTGSSEVQVALLTFRINDLTPHFK
                     ANPKDHHSRRGLLKMVSQRRRLLAYLRRTQPDTYRALITRLGLRK"
     gene            complement(5297..6232)
                     /gene="secF"
                     /locus_tag="ACFOAE_001430"
     CDS             complement(5297..6232)
                     /gene="secF"
                     /locus_tag="ACFOAE_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HFC6884897.1"
                     /translation="MELFKIKRDIPFMSYGKLTTFISLVTFIAAVFFLVTRGLNFSVE
                     FTGGTVMEVQYQQGADVNKMRERLDTLKIGDVQVQALGTNKHIMIRLPNKEGVTSAQL
                     SNQVMDLLKKDSPDVTLRQVEFIGPQVGEELVSNGLMALGFVVIGIIIYLSMRFEWRF
                     AVSAIIANMHDIVIILGCFAFFQWEFSLTVLAGILAVLGYSVNESVVVFDRIRENFRK
                     PAMRGHAVPEVIDNAITATMSRTIITHGSTEAMVVSMLVFGGTALHGFSMALTIGIVF
                     GIYSSVLVASPLLLMFGLSRDNIGKEPKKKEEIVV"
     gene            complement(6236..8089)
                     /gene="secD"
                     /locus_tag="ACFOAE_001431"
     CDS             complement(6236..8089)
                     /gene="secD"
                     /locus_tag="ACFOAE_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HFC6884898.1"
                     /translation="MNRYPLWKYLLIVFTIAVAAVYSLPNLFGETPAVQVSTNRQAII
                     INEQTQSKVDAALKNAGIQTDGMFVVDNSLKVRFKDTETQLKARDVIENTLGEGYITA
                     LNLLADSPEWMAKIKANPMFLGLDLRGGVHFTMQVDMKAAMQKTFERYSGDIRRELRR
                     EKIRSGTVRQAGNSLTVPLQDAGDVQKALPQLRKLFPEATLNSDGSNIVLTLSEEAVN
                     KVRSDAVKQNITTLHNRVNELGVAEPVIQQSGADRIVVQLPGVQDTAKAKDIIGRTAT
                     LELRMVEDDPAKLREALEGNVPSGYELLSSGGDRPETLLISKQVELTGDNINDAQPSF
                     DQMGAPAVSLSLDSAGGSIFGELTAANVGKRMAMVLIDQGKSEVVTAPVIRTAITGGR
                     VEISGSMTTAEANDTSLLLRAGSLAAPMQIVEERTIGPSLGKENIEKGFHSTLWGFAI
                     VAAFMVVYYRLMGFFSTIALSANILFLIGILSAMQATLTLPGMAALALTLGMAIDSNV
                     LINERIREELRAGVPPQQAINLGFQHAWATIVDSNLTSLIAGIALLVFGSGPVRGFAV
                     VHCLGILTSMYSSVVVFRALVNLWYGRRRKLQNISIGSVWKPKAEMAGGKE"
     gene            complement(8301..8567)
                     /gene="yajC"
                     /locus_tag="ACFOAE_001432"
     CDS             complement(8301..8567)
                     /gene="yajC"
                     /locus_tag="ACFOAE_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFC6884899.1"
                     /translation="MNQAVAQFAPLVLIMVVFYFLIMRPQQKKFKAHQAMLAALKVGD
                     KVVLAAGFKGKVTRVGEQFFTVDIGQGTKIEVEVERNAIAAKVD"
     gene            8695..>9795
                     /locus_tag="ACFOAE_001433"
     CDS             8695..>9795
                     /locus_tag="ACFOAE_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone deacetylase family protein"
                     /protein_id="HFC6884900.1"
                     /translation="MSLTRLILKFYALLRLFLGKNARTAWISHPACAGHEPGANHPDS
                     PDRILCIEQALRRAGIWQHLQTIEAEEISDTRLALVHSSKYLNRLESCLPQKGKISRL
                     DNDTAISTGSLSAARFAAGSAVQAVDMVMNRKAWHAFCAARPPGHHAGSGKAGGFCLL
                     NNVAAGVMHAVAEYRLKRIAVIDFDVHYGDGTAEIFKDDPRILFFNLFETDLFPFPEN
                     NDMPDGGNMVHLPLPPGTGSRTFREAVRRQWLPRLAAFKPELVLLSAGFDAHRLDESG
                     RLNLHEADFAWLTHKIIQTASGCPGKIVSVLEGGYTLEPLAQSAAEHIRVLAGLGKSD
                     AATAYQKTLDPTKKRFAKPKTGQVRQPTQSDRY"
BASE COUNT         2500 a         2598 c         2442 g         2255 t
ORIGIN      
        1 cctgcgacgc ttaacggctg tctttccact gataatattt cgagccgagg aaagaaccga
       61 gtttgcgcaa aaacggttgc aggataatat tcggctggcg caaccgctca aacggcttca
      121 gacggcattc gtcccctaaa attgcttcgg caaccgccag acctgcaatg cctgttatcg
      181 ccatcccgtg tccggaataa ccttgcgtat aaaaaacatt cggggctaaa cgtccgaaat
      241 gcgggacaag gttggcggta atgtcgcact ccccgcccca cgaatattcg attttgacat
      301 cggcaagctg cggaaaaact ttaagcatat cttggcggac aagctcggtc atacgcgcgg
      361 gattgtcgat aaactcgtta tccttaccgc cgaaaagcag tctgccgtcc gcgctgaggc
      421 ggtaataatc caaaatatgg cggttgtcgc atactgccat attgttgcgg ataagccctt
      481 ttgcacgcgc gcccaagggt tcggtggcaa taataaaggt gctgacagca atcgccttgc
      541 gctccaaagg cttgaatatc ggattcaaac cggcataagt attgacggcg tacactagat
      601 ttttgcattc gacgctgcct tcgggggtgt aaaccagcca accgttttga tgcggttcga
      661 tgcgcgtcat cggggactgc tcgaaaatct gtgcgccggc ttcggcagcg gcgcgggcga
      721 tgcccaacgt gtaattgagc ggatggagat gcccggacaa gggatcgaac tgtgcgcctt
      781 ggtacatatc gctgtcaagc tgctgcttca gttcagtgtt atcccagagt tgataatgac
      841 tcgcaccgta atgccgttgg gcgtgttcat gccactgctg caactcttcc caatgctgcg
      901 gacggacggc aaccgtggca taaccgcgct gccaatcgca atcaatggca tgtttgcgga
      961 cgcgttcgtc caccagttcg accgcctgca aagactgttg ccaaaaccat tgcgcctgct
     1021 ccaagccgac ctgtttttca atttccccca taccgcaggc gtaatcgctg ataacctgcc
     1081 cgccactccg tcccgacgcg ccgaaaccga tacgcgcggc ttccaacaca accgtttcat
     1141 gtccctgctc cgccaagggc aatgcagtgc acaaaccact caatccgccg ccgatgatac
     1201 aggtatcggt tttcagacgg cattgaagtt tcggataaac agtatgagga ttaaccgaac
     1261 tgaaataata agaaggcaga tattcttgaa aatcagggcg aatcattgtg tttgctttat
     1321 caggtgtatt ttcggacgga atgatacagg ctgtcgggcc atatcgtcca aacagaaaat
     1381 cggttgaaga aaacaggctg acccagtcat gcggtcagcc tgccttatta attaatttgc
     1441 tttctcggca gccaattttt cttggcggta ggcttctgcc gcttctcggt cacgcttggt
     1501 tgcctgcctc atcatccaat aattgacgat gatgaccaat gttccgatga tgccgattag
     1561 gatggtcgcc aagacattca tctgaggatc aagacccagc ttgattttgg agaaaatcac
     1621 ctgcggcaat gtggatgaac cggggccgga gaggaatgag gtaattacca aatcatccaa
     1681 agacagggta atgccgagca gaaagcctga agcgatggca ggggcaatca aaggcaaagt
     1741 gatgacaaaa aagattttca gcggacgcgc gcccaaatcc attgcggctt cttcgagcga
     1801 ttggtcaagc tcaaccagac gcgaacggat aacaacggta atgtacgcca tacacagcgt
     1861 cgtatgtccg aggaagatgg tgaaaaagcc acgatcgaag tagagatgtt gtaaccattc
     1921 gctgccctgc aaaaatatct gtacctgaat aatcagcagc agcatagaca gaccggtaat
     1981 cacgtcgggc atcaccatag gtgcggaaat cataccggcg aacaaggtac tgccgcgaaa
     2041 acgtttaatc cgcgccatcg catagcctgc cagcgtgccc aaaacgacgg cggcaagcga
     2101 agacacaacg gcaatccgca gcgacagcca agcggcttcc aagatggtgt cgttttccag
     2161 caatgcgccg taccacttgg tcgaaaagcc gccccaaacg gttaccagct tggattcgtt
     2221 aaacgaatag atgaccaaaa caaccagcgg gatatacaga aacgccagcg acagtgccaa
     2281 catcagtttc aagaaccaag ataatttgga tttctgcatt atttggctcc ttcttccaat
     2341 tcgcggtttt cataatgctg aaacagggca atcggcacga ccagcagcgc gaccatcacg
     2401 acggcgacgg cggaagccag cggccagttg ttttgatcga agaacgcctg ccacaagact
     2461 ttaccaatca tcaggttttc cgaaccgccg accagctcgg gaatgacgaa ctcgccgaca
     2521 gcagggacga aaaccagcat ggagcctgca ataatgccgg ttttcgacaa aggcagggta
     2581 atcgtcaaga acgatttgac cggccccgcg cccaaatcgg aagccgcttc aagcaggcgg
     2641 ttgtcgagtt tcaccagttg cgtgtatagc ggcagaatca taaacggcag ataggcgtaa
     2701 accatcacca aattgagcga aaaggcattg tagaacaaat ccaaaggctc gctgataata
     2761 cccattttaa tcaacaggtt gtttacaatg ccgttatgcc cgagcagacc catccacgca
     2821 tagacgcgca acaggaacga tgtccaaaag ggcagcataa tggcaagcag caaaccattg
     2881 cggacagaag gattggcacg agaaatcgca taggcggtcg gataaccgac caacagacaa
     2941 attaccgtcg tagtcagcgc agtcttaatt gaagaccaat aagtcatcag atagatattg
     3001 ctgttttcac cgtcgccgaa cggattgagc gtactccaaa aattttggaa gatgtctgca
     3061 taattttggt agctgacagc aatattcaga cgacccaaat cctcatctat cgtcgttaaa
     3121 ggagtaaacg gcgggatggc gatttcttgt tcggcaaagc tgattttcag cacgatggcg
     3181 aacggaatca gaaacagcac caaaagccaa atatacggta cggcaatcac cgcacgctgc
     3241 cccggacggc ggaacagttt gtttttcagt ttattaaggt tcattgcatt ccccttaaat
     3301 caacggaaca acggagtcgg ttggttttcc ggccagctga tatagacggt ttcgtcccaa
     3361 gtcggcggtg taatgttgcg cacataccag taaggggcgg ggacttggct tttgacgacg
     3421 cgcccgttgc cgagcttgat atggtaaatg gcgaagctgc ccaaataggc gatttctttt
     3481 accgtgcctt tcgcccagtt gtagtcgccc aaatattcgg gtttttcttt atataaatca
     3541 atatcctctg gtcgaatact aacccaaagg tcctgctcgc tcggaccacc caaaccgtga
     3601 tcgatgcgga cgtggttttc caaaccttcg cattcgataa cggcatagtc ggcatgatct
     3661 tcaatcacca caccgtcaaa gatgttggtt tcgccgataa actcggcagt gaagcggctg
     3721 ttgggatagt cgtacacgtc gctgggtgtg ccgacttgct gcaactgacc gtcagacata
     3781 atggcgatgc gggtcgccat cgtcatcgcc tcttcttggt cgtgcgtaac cataatacag
     3841 gttacgccga cttgttccag cgtattgacc aactcaagct gggtttgttg gcgcagtttt
     3901 ttgtccaatg caccgagggg ctcatccagc agtagaattt tcggacgttt tgccagactg
     3961 cgtgccaaag caatgcgctg ctgctgaccg ccggacaatt ggtgcggttt gcgtttagca
     4021 aatttggtca tctgaaccag gcggagcatt tcttcgacgc gcgcggcgat ttcgccttta
     4081 ggcattttgt cctgtttcag accgaaggca atgttttgtt ctacggtcat atgcggaaaa
     4141 agcgcgtaac tttggaacat catattgatg gggcgatcat agggtgcaag tttggtaata
     4201 tcctgaccat caaggataat ttttccctga ttgggatttt ccatacccgc cagcatacgc
     4261 agcagtgtag attttccgct gccggaactg cccaaaaggg cgaagatttc gtgttgataa
     4321 atgtccaagt cgatgttatc gacagcgtaa ttgtcaccaa actttttcac caaaccttgg
     4381 atttgcagat aaggcttggt tgaagacgca gtggttgcgg tcataatggc aatactccaa
     4441 taaaaagacg agtaccggca aaacggatgt tcgaatgggt gataaaaagc tgtttgattg
     4501 ctggcgggag ttaaacgttt gatgccgtct gaaactcttg taaagcgcac gggcagcatg
     4561 aaatggaaca agattccaaa gaactttata ttatattagt ttatgcggtt ttcgggcaat
     4621 atagtggatt aaatttaaac cagtacagcg ttgccttgcc ttgccgtact atttgtactg
     4681 tctgcggctt cgtcgccttg tcctgattta aatttaatcc actataaata tggatttgag
     4741 cttgtcggaa agcaacagaa aagaaaacac cgcccatttt tctgggcggt gtcggaaagc
     4801 gtaattattt acgcagaccc aagcgggtaa tcaacgcgcg atacgtatcg ggctgggtac
     4861 ggcgcaagta ggccagcagg cggcggcgtt ggctgaccat tttcaacagg ccgcgacggc
     4921 tgtggtggtc tttggggttg gctttgaagt ggggggtcag gtcgttgatg cggaaagtca
     4981 acagagcgac ttgtacttcg gaagagccgg tgtcgccttc tttgcgttgg aaatctttaa
     5041 cgatttgtgc tttttgttct acggtcagtg ccataatgaa aactccaaaa atataagaat
     5101 ccccataggg attcagacaa gtttgccaag cctgaagaca acggcaaact ccctatgccc
     5161 aagataggac aacgtggcat tatgacacaa ttcccgcatt tctgcacaat attttaagac
     5221 cgtggaagta accgttaaaa atgccgtctg aagcattgtc tgcttgagac ggcaatgttc
     5281 agacggcata tgcgcttcaa accacgattt cttctttctt cttcggttct ttaccgatat
     5341 tgtcgcggct caaaccgaac attagcagaa gcgggctggc aaccaatacg gaagaataaa
     5401 tgccgaacac gatgccgatg gtcaacgcca tagaaaagcc gtgcaaggcc gtaccgccga
     5461 acaccagcat ggatacgacc atcgcctcgg tcgaaccgtg ggtaatgatg gtgcggctca
     5521 tcgttgcggt aatcgcgttg tcgatgactt ccggcacggc atgtccgcgc atcgccggct
     5581 tgcggaagtt ttcacggata cggtcgaaga cgacgacgga ttcgttcaca gaatagccca
     5641 atacggcaag gatacccgcc aagacggtca gcgaaaattc ccattggaag aaggcaaagc
     5701 agccgagaat aatcacgatg tcgtgcatat tggcgataat ggcagatacg gcaaaacgcc
     5761 attcgaaacg catcgacagg taaataatga tgccgataac gacaaaacct aaagccatca
     5821 atccattact taccaattcc tcaccaactt gcgggccgat aaattcgact tggcgcaaag
     5881 taacgtcggg actgtctttt ttcagcaaat ccataacctg attggacaac tgtgcggaag
     5941 taacaccttc tttgttcggc aggcggatca tgatgtgttt gttcgtaccc aatgcctgaa
     6001 cctgtacatc acctattttc agcgtatcga ggcgttcgcg catcttattg acatccgcac
     6061 cctgctgata ttggacttcc attaccgtgc cgccggtaaa ttcgacagag aaattcagac
     6121 ctctggtaac caaaaagaat acggcggcaa taaaggtaac caacgaaata aaggtcgtca
     6181 gtttgccgta gctcataaac ggaatatcgc gtttgatttt aaagagttcc atagcttact
     6241 ccttgcctcc tgccatttcg gctttcggct tccacaccga accgatggaa atattctgca
     6301 atttgcgtct gcgtccatac cacagattga ccaacgcacg gaatacgacg acggacgaat
     6361 acatcgaagt cagaataccc aaacagtgta cgaccgcaaa accgcgtacc gggccggaac
     6421 cgaataccaa aagcgcgata ccggcaatca gcgaagtcag gttggaatcg acaatggtcg
     6481 cccatgcgtg ttggaaaccg agattgattg cctgctgcgg cggcacgccg gcacgcaatt
     6541 cttcgcggat acgttcgtta atcaagacgt tggagtcgat tgccataccc aaagtcaacg
     6601 ccagcgcggc catacccggt aacgtcaacg ttgcctgcat ggcagacaaa ataccgatta
     6661 ggaacagtat gttggcactc aatgcaatgg tagaaaagaa acccatcaga cgatagtaaa
     6721 ccaccatgaa tgcagcaacg atggcaaaac cccataaagt cgaatggaag cctttttcga
     6781 tgttctcctt acccaaagac ggaccgatgg tacgttcttc gacaatctgc atcggcgcgg
     6841 caagagaacc ggcacgcaac agcaaagacg tatcattggc ttcggctgtc gtcatgcttc
     6901 cggaaatttc cacgcgtccg ccggtaatgg cagtacggat aaccggcgcg gttacaacct
     6961 cggattttcc ttggtcgatc aaaaccatcg ccatgcgttt gccgacattt gcggcagtca
     7021 gttcgccaaa aatgctgcca cccgcgctgt ccaagctcag actgacagca ggtgcgccca
     7081 tttggtcgaa actcggttgc gcatcgttga tgttgtcgcc cgtcagctcg acctgtttgc
     7141 tgattagcag agtttcggga cgatctccgc cgcttgaaag cagctcataa ccgctcggca
     7201 cgttgccttc caatgcctcg cgcaacttgg caggatcgtc ctccaccata cgcaattcca
     7261 aagtcgcggt acggccgatg atgtcttttg ccttggcagt atcctgaacg cccggaagct
     7321 gcacgacgat acggtcggca ccggactgct ggatgacggg ttcggccacg cccaactcgt
     7381 tcacacggtt gtgcagggta gtgatgttct gtttgaccgc atcggaacgc actttattga
     7441 ccgcctcttc cgaaagcgtc aagacgatat tgctgccgtc tgaattcagc gttgcttcag
     7501 gaaacagctt gcgcaactgc ggcagtgcct tttgcacatc acctgcatcc tgcaaaggga
     7561 cggtcaggct gtttccagcc tgacgcaccg tgccgctgcg gattttttcg cggcgcagtt
     7621 cgcggcggat gtcgcccgaa taacgttcaa acgttttctg catcgccgct ttcatatcga
     7681 cctgcatggt gaaatgcacg ccgccgcgca ggtccaaacc caaaaacatc ggattggctt
     7741 tgattttcgc catccattcg gggctgtccg ccaacaggtt gagcgcggta atataccctt
     7801 cgcccaaagt gttttcgatg acgtcgcgcg ctttaagctg cgtttctgtg tctttgaaac
     7861 gcactttcag tgaattgtcc acaacaaaca tcccgtcggt ctgaatacct gcgtttttca
     7921 gcgcggcatc cactttggat tgagtctgtt cgttgatgat gatggcttgt cggttggtcg
     7981 atacctgcac ggcgggtgtt tcgccgaata ggttgggcag cgaatacact gcggcaaccg
     8041 caatcgtgaa cacaatcagc agatatttcc ataaaggata acggttcatc attgttcctt
     8101 aatggttgga accccaccct ttcggtggtg tcggaatcgg gctatttcag aagaggcaaa
     8161 aacccttccc agccaggcaa gaccggaagg cggcatcttg aatatgccgc cctgcgtgtc
     8221 ggaacatggt caagccttcg gttggaattc aaaacaaagt gccgcattcg ggctttccag
     8281 atgcggcttg tcggcacaaa tcaatcgact tttgcggcaa tcgcattgcg ttctacttcg
     8341 acctcgattt ttgtaccctg tccgatatcc acggtaaaaa actgttcgcc gactctggtt
     8401 accttaccct tgaaacctgc cgccaagacc actttgtcgc cgactttcaa ggcggcaagc
     8461 attgcctgat gcgctttgaa tttcttttgc tgcggacgca tgatcaggaa gtagaacacc
     8521 accataatca acactaaagg agcaaattgt gcaacagctt gattcataat ttatccgttc
     8581 tttctaatat ggttgaaaat cgagaggggt atataataac ataagaccgt aaacaatata
     8641 tcgggtttgc cgtccgtacc gaccgtatac cgcagcctgc ccgtccacaa acccatgtcc
     8701 ttgacccgcc taatcttgaa attctatgca ctgttgcgcc tttttttggg caaaaacgcc
     8761 cgcaccgcat ggatttcgca tcccgcctgt gccgggcacg aacccggcgc aaaccatccc
     8821 gattcgcccg accgcatcct ctgcatcgag caggcattgc gccgcgccgg tatttggcag
     8881 cacctccaaa ccatagaggc ggaagaaatc agcgatacgc gcctcgcact tgtccactcg
     8941 agcaaatatc tgaaccgttt ggaatcttgc ctgccccaaa aaggcaagat ttcccgcctg
     9001 gataacgaca ctgcaatcag cacaggctcg ctgtctgccg cacgctttgc cgccggttcg
     9061 gcagttcagg cagtcgacat ggtcatgaac cgtaaagcat ggcatgcctt ttgcgccgcc
     9121 cgcccgcccg gacaccatgc gggcagcggc aaagccggcg gattctgcct gctgaacaac
     9181 gttgccgccg gcgtcatgca tgccgttgcc gaataccgcc tgaaacgcat tgccgtcatc
     9241 gatttcgatg tccactacgg cgacggtacg gcagaaatat tcaaagacga tccgcgcatc
     9301 ctgtttttca acctgtttga aaccgacctt ttccccttcc ccgaaaacaa cgatatgccc
     9361 gacggcggca atatggtgca cctgcccttg ccgccgggaa cgggcagccg cacattccgc
     9421 gaagccgtcc gcaggcagtg gctgccccga cttgccgcat tcaaacccga actggtgctg
     9481 ctgtcggcag gattcgacgc acaccgtcta gacgaatcgg gcaggctcaa cctgcacgag
     9541 gcggattttg cctggctgac acacaaaatc attcagacgg catcgggctg ccccggcaaa
     9601 atcgtatccg tactcgaagg cggctacacc cttgaacctc tggcacaatc tgctgccgag
     9661 catatccgcg tgctggcagg gctgggcaaa tccgatgccg caaccgccta tcagaaaaca
     9721 ctggacccaa caaaaaaacg gtttgccaaa ccgaaaaccg gacaggtgcg ccaacctacc
     9781 caatccgacc gttac
//
LOCUS       DAXIDM010000068         9764 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000068 DAXIDM010000000
VERSION     DAXIDM010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9764
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.068"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            580..1397
                     /gene="opc"
                     /locus_tag="ACFOAE_001434"
                     /gene_synonym="opcA"
                     /pseudo
     CDS             580..1397
                     /gene="opc"
                     /locus_tag="ACFOAE_001434"
                     /gene_synonym="opcA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222545.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Opc"
     gene            1560..2204
                     /locus_tag="ACFOAE_001435"
     CDS             1560..2204
                     /locus_tag="ACFOAE_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HFC6884901.1"
                     /translation="MLASAIDFILHIDQHLLALSAQYGVWIYAILFLIVFCETGLIVT
                     PLLPGDSLLFAAGGIAALGGMDIHLMVALLSLAAILGDALNFTVGKYFGGRLFANPDS
                     KIFRREYLDKTHRFYEKHGGKTIIIARFMPIVRTFAPFVAGMGKMHYAKFIRYNIIGG
                     LLWVILFSYAGYFFANFPVVKNNLGLVMGGIIIVSVLPGAVEIARAKLAVKSKR"
     gene            2223..4133
                     /locus_tag="ACFOAE_001436"
     CDS             2223..4133
                     /locus_tag="ACFOAE_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFC6884902.1"
                     /translation="MNILSVENASFAIGHVALLDKTSFQLDSGEKVGLIGRNGAGKSS
                     FLKILAGLQKLDDGQIIVQNNLKIVYVPQESFFDKDATVFDTVAEGLGEIRDLLRRYH
                     HVSHDLEHNSDDVLLKELNELQLEIEAKDGWKLDAAVKQTLGELGLPENEKIGNLSGG
                     QKKRVALAQAWVQKPDVLLLDEPTNHLDIDAIIWLENLLKAFEGSLVVITHDRRFLDN
                     IATRIVELDRGILRSYPGSFSKYSEKKAQELAVEAEHNRLFDKFHAQEEAWIRKGIEA
                     RRTRNEGRVRRLEELRRQRAERRNVQGQVNFKLDSGEKSGKIIAELEHASFAYGGKVI
                     MDKFSAILQRGDKIGLIGPNGIGKTTFLKLILGELQPTYGRIRIGSKQEVAYFDQFRS
                     ALNENDTVFYTLGQGNDYVEVGGKKKHVMSYLEDFLFPPARAQSPVSSLSGGERNRLL
                     LAKLFTRPANILILDEPTNDLDIDTQELLEDLLRDYQGTVFLVSHDRMFLDNVITQSI
                     IFEGNGRLKEYIGGYQDYIDAKSREAKIQTESAPKTADAEPVKEKPKANRTVKLSYKE
                     QRELDALPDEIAALEAEQAEINAQLSDPEIFKDYEKAGALQSRAEEIEMLLLEKLERW
                     ELLETKQNGNAV"
     gene            4154..4519
                     /locus_tag="ACFOAE_001437"
     CDS             4154..4519
                     /locus_tag="ACFOAE_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884903.1"
                     /translation="MFKRPEEIIVLILAVLWIAGTYFLAALFGADAYTVLKITALTLL
                     WSAASFLLWQKNLSRHIWPLLLGCLTACWWPYLNQSVAPGSLPWYASWTFKTILALIP
                     VTAGYLFKWKQYRQRKTKP"
     gene            4630..6105
                     /gene="trpE"
                     /locus_tag="ACFOAE_001438"
     CDS             4630..6105
                     /gene="trpE"
                     /locus_tag="ACFOAE_001438"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HFC6884904.1"
                     /translation="MISKQEYQAQAAQGYNRIPLVQELLADLDTPLSLYLKLANRPYT
                     YLLESVVGGERFGRYSFIGLPCSHYLKASGKHVDVYQNGEIVEQHDGNPLPFIEAFHN
                     RFKTPEIPSLPRFTGGLVGYFGYETIYNFEHFAHRLKNTTKADPLGTPDILLMLSQEL
                     AVVDNLSGKIYLIVYADPSQPDGYERARERLEDIRTQLRQSCAIPLSLGSKHTEAVSE
                     FGEEPFKACVNKIKDYIFAGDCMQVVPSQRMSMEFTDSSLALYRALRTLNPSPYLFYY
                     DFGDFHIVGSSPEILVRRERDDVIVRPIAGTRLRGKTPAEDLANEQDLLSDAKEIAEH
                     VMLIDLGRNDVGRISKTGEVKVTDKMVIEKYSHVMHIVSNVEGRLKDGMTNMDILAAT
                     FPAGTLSGAPKVRAMEIIEEVEPSKRGIYGGAVGVWGFNNDMDLAIAIRTAVVKNNTL
                     YVQSGAGVVADSDPASEWQETQNKARAVIHAAQMVQEGLDK"
     gene            6102..6647
                     /locus_tag="ACFOAE_001439"
     CDS             6102..6647
                     /locus_tag="ACFOAE_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFC6884905.1"
                     /translation="MTYEKLYELRQTLRPTTKDGLYTDNEKSREILTVRWSGNTENPK
                     NFSAVAIGINPSKANDERSDKTLTQLARFLDMYGFTNFKMLNIFSSYSTQQTGIRANT
                     QTDFSKFKGCLEDADMIILAWGTDRGAYKDEKNRILEFLKAEKFMEKVFCISETGNSS
                     DTRHPSRISYSYQLVQFEESA"
     gene            6644..7780
                     /locus_tag="ACFOAE_001440"
     CDS             6644..7780
                     /locus_tag="ACFOAE_001440"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFC6884906.1"
                     /translation="MKNISLSPPAMLGILGGGQLGRMFTVAAKTMGYKVTVLDPDPDA
                     PAAEFADCHLCAPFNDQAALDELAKCAAVTTEFENVNADAMRFLAKHTNVSPGSDCVA
                     IAQNRIQEKAWIRKAGLQTAPYQAICKAEDITEESIQFLPGILKTATLGYDGKGQIRV
                     KTVDELKAAFAEHRGVDCVLEKMVDLRGEISVIVCRLNNDNVQTFDPAENIHENGILA
                     YSIVPARLSADIQQQARQMAQRLADELNYVGVLAVEIFVVGDTHELVVNEIAPRPHNS
                     GHHTVDACAADQFQQQVRLMCNLPPADTKLLSSCCMANILGDVWQEDGGEPDWFPLQS
                     RPDAHLHLYGKKTAHKGRKMGHFTVLTTDSDTAFQEAKKLHQSL"
     gene            7827..8309
                     /locus_tag="ACFOAE_001441"
     CDS             7827..8309
                     /locus_tag="ACFOAE_001441"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFC6884907.1"
                     /translation="MSLLTLLRPATVQDCKDIFKVHLHSVQYTCILSYNEHALKVWEG
                     LLNTESYLPTISDPDKALWVAEYKGNIQGFFQIDCQEAQLDALYVHPLFHNLGLGTAL
                     LHQAETIAHKSGLSFLKLYASLNSVPFYLLNRYESLGSAVLQLDPSIKIKCELMRKHL
                     "
     gene            8415..9470
                     /locus_tag="ACFOAE_001442"
     CDS             8415..9470
                     /locus_tag="ACFOAE_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6884908.1"
                     /translation="MKTYAPALYTAALLTACSPTADSNHPSGQNAPANTESDGKNITL
                     LNASYDVARDFYKEYNPLFIKTYQSEHPGTSVSIQQSHGGSSKQALSVANGLQADVVT
                     MNQSSDIDLLEKKGLVEKGWQQALPDHAAPYTSTMVFLVRKNNPKQIRDWNDLAKDGV
                     NIVIANPKTSGNGRYAFLGAYGYGLKTTNGNEQEAQKLVASILKNTPVFENGGRAATT
                     TFTQRNIGDVLITFENEANYVSKKLTQGQFEIVYPSYTISAESPVAVVNSVVAKKGTQ
                     KTARAYLEYLWSEPAQELAASLYLRPRNPEVLARHKAYFPDLDTFSPEEKFGGWDNIM
                     KTYFADGGIFDRLTAQK"
     gene            9467..9664
                     /locus_tag="ACFOAE_001443"
     CDS             9467..9664
                     /locus_tag="ACFOAE_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884909.1"
                     /translation="MTAMPSEPPFRRHFTHQNRKTAPKIIITRHNGKPDTKPNTAAKM
                     PSEAVGATILIWGITFLNHPF"
BASE COUNT         2747 a         2743 c         2139 g         2135 t
ORIGIN      
        1 gaccggatgc ctgattatcg ggtatccggg gagggttaag ggggtatttg ggtaaaatta
       61 ggaggtattt ggggcgaaaa tagacgaaaa cctgtgtttg ggtttcggct gtcgggaggg
      121 aaaggaattt tgcaaagatc tcatcctgtt attttcacaa aaacagaaaa ccaaaaacag
      181 caacctgaaa ttcgtcattc ccgcgcaggc gggaatccag acccccaacg cggcaggaat
      241 ctatcggaaa taaccgaaac cggacgaacc tagattcccg ctttcgcggg aatgacggca
      301 gagtggtttc agttgctccc gataaatgcc gccatctcaa gtctcgtcat tcccttaaaa
      361 cagaaaaccg aaatcagaaa cctaaaattt catcattccc ataaaaaaca gaaaaccaag
      421 tgagaataac aattcgttgt aaacaaataa ctatttgtta atttttatta atatatgtaa
      481 aatccccccc gaaagcttaa gaatataatt gtaagcgtaa cgattattta cgttatgtta
      541 ccatatccga ctacaatcca aattttggag attttaacta tgaaaaaaac agtttttaca
      601 tgtgccatga ttgccctgac cggtactgcc gccgctgcac aagagcttca aaccgctaat
      661 gagtttaccg tccacaccga cctctcttcc atttcttcaa ctcgtgcttt cctgaaagaa
      721 aaacacaaag ctgccaaaca catcggcgta cgtgctgata ttccttttga tgccaaccaa
      781 ggcatccgct tggaagccgg tttcgggcgc agcaaaaaaa tattattaat ttggaaacag
      841 atgagaacaa gctgggtaag actaaaaatg taaaactgcc caccggcgtt cctgaaaacc
      901 gtatcgatct ttacacaggc tacacctata cccaaacgtt aagtgattct ttaaatttcc
      961 gtgtgggtgc cggcttgggt tttgaatctt caaaagacag cattaaaacc accaagcata
     1021 cgcttcacag cagccgtcag tcgtggttag ccaaagttca cgcggatttg ctttcccaac
     1081 tgggtaacgg ctggtatatc aacccttggt ctgaagtgaa atttgacctc aattcccgct
     1141 ataaattaaa caccggcgtt accagtctca aaaaagacat caatcaaaaa accaacggct
     1201 ggggctttgg attgggtgca aatattggta aaaaactggg cgaatccgcc agcatcgagg
     1261 cggggccgtt ctacaaacaa cgcacttaca aagaatccgg cgagtttagt gtaacaacca
     1321 cgagtggcga cgtatcgctc accatcccga aaaccagtat tcgtgaatac ggcttgcgcg
     1381 tcggcataaa attctgatga tttgaaatca tcattgtcac tttaaatgcc aaaccgcaaa
     1441 ctattttggt ttgcggtttt tacgtgaaat gaatttgaat agccgatgcc gtctgaaaat
     1501 ttcagacggc atttttccaa tcggttaaaa tacgcggttt gtttttttag gaacgcgccg
     1561 tgcttgcctc cgccatcgac ttcatcctcc atatcgacca acacctgctc gcgctgtcgg
     1621 cgcaatacgg tgtgtggatt tatgcgattc tgtttttgat tgttttttgc gaaaccggcc
     1681 tgattgttac gcccttactg cccggcgatt cgctgctgtt tgccgccggc gggattgccg
     1741 cgctgggcgg tatggatatt catttgatgg ttgcattatt aagccttgcc gccatactcg
     1801 gcgacgcgct caattttacc gtcggcaaat atttcggcgg caggctgttc gccaaccccg
     1861 attctaaaat cttccgacgt gaatatctcg ataaaaccca ccgtttttac gaaaaacacg
     1921 gcggcaaaac catcatcatt gcccgtttta tgcccatcgt ccgcaccttc gcccccttcg
     1981 tcgccggtat ggggaaaatg cactatgcca aatttatccg ctacaacatc atcggtggct
     2041 tgttgtgggt tatcctgttt tcttacgcgg gctatttctt tgccaacttc cccgtcgtaa
     2101 aaaacaatct gggcttggtg atgggcggca tcattattgt ttccgtcctg ccgggtgcgg
     2161 ttgaaattgc ccgcgccaaa cttgcggtaa aatccaaacg gtaactgttg agaatttgta
     2221 tcatgaatat attatctgta gaaaacgctt cttttgccat cggccacgtt gccttgctcg
     2281 acaaaacttc ttttcaactc gacagcggcg aaaaagtcgg cttaatcgga cgcaacggcg
     2341 caggcaagtc ttcgttttta aaaatcctcg ccggtttgca aaagctcgac gacgggcaga
     2401 ttattgttca aaacaacctc aaaatcgttt atgtaccgca ggaatccttt tttgataagg
     2461 acgcaaccgt atttgatacc gttgccgaag gtttgggcga aattcgcgat ttattgcgcc
     2521 gttatcatca tgtcagccat gatttggagc acaattcaga cgacgtttta ttaaaagaac
     2581 tcaacgaatt acaactcgaa atcgaagcga aggacggctg gaagctggat gcggcagtca
     2641 agcagacttt gggcgaactc ggtttgccgg aaaacgaaaa aatcggcaac ctttccggcg
     2701 gtcagaaaaa gcgtgtcgcc ttggcgcagg cttgggtgca gaagcccgac gtattgctgc
     2761 tggacgaacc gaccaaccat ttggatattg acgcgattat ctggttggaa aacctgctca
     2821 aggcgtttga aggcagcttg gtcgtgatta cccacgaccg ccgttttttg gataatatcg
     2881 ccacgcggat tgtcgaactt gaccgcggca ttctacgttc ctatcccggc tcgttctcta
     2941 aatacagtga gaaaaaagcg caagagttgg cagtcgaggc ggaacataac cgcttgtttg
     3001 acaaatttca tgctcaggaa gaagcgtgga tacgcaaagg cattgaagcg cgccgtaccc
     3061 gtaacgaagg ccgcgtgcgc cgcttggaag agctgcgccg ccaacgtgca gaacgccgca
     3121 acgtgcaggg acaggtcaac tttaagctcg acagcggtga gaagagcggc aaaatcatcg
     3181 ccgaattgga gcacgcttcg tttgcctacg gcggcaaagt cattatggac aaattctccg
     3241 ccatcttgca gcgcggcgac aaaatcggct taatcggtcc aaacggcatc ggcaaaacca
     3301 catttttaaa actgattttg ggcgaattgc agccgaccta cggcagaatc cgtatcggca
     3361 gcaagcagga agtcgcctat ttcgaccagt tccgcagcgc gttgaatgaa aacgacaccg
     3421 tgttttacac gctcggacag ggcaatgatt acgttgaagt cggcggtaag aaaaagcatg
     3481 tgatgagcta tttggaagat ttcctgttcc cccctgcccg cgcgcaaagt cccgtttcat
     3541 cgctctccgg cggcgaacgc aaccgccttt tgctggcaaa actctttacc cgtcctgcta
     3601 atattttgat tttggacgaa ccgaccaacg acttggatat cgatacccaa gagctgcttg
     3661 aagatttgct gcgcgattat caaggcacgg tattccttgt ctcacacgac cgtatgttcc
     3721 tcgataacgt gattacccaa agcattattt ttgaaggaaa tggaaggtta aaagaatata
     3781 tcggcggcta tcaggactac atcgacgcaa aatcacgcga agcgaagatt cagacggaat
     3841 ccgcacccaa aacagccgat gccgaaccgg tgaaagaaaa acccaaagcc aaccgcacgg
     3901 tcaaactgtc ctacaaagaa cagcgcgaac tcgacgccct gcccgacgaa atcgccgcct
     3961 tggaagccga acaggcagaa atcaacgcgc agctttccga tcccgaaatc ttcaaagatt
     4021 acgaaaaagc cggcgcactg caaagccgcg ccgaagaaat cgaaatgctg cttttggaaa
     4081 agctggaacg ctgggagctg ctggaaacca aacagaacgg caatgccgtc tgaaatcaaa
     4141 caggaagaaa aaaatgttca aacgacctga agaaatcatt gtcctgatac ttgccgtcct
     4201 ctggattgcc ggtacgtatt ttctcgccgc cctgtttgga gcggatgctt ataccgtgtt
     4261 aaaaatcact gcccttaccc tgctttggtc tgccgcatca ttcctccttt ggcaaaaaaa
     4321 cctcagccgg catatctggc cgctgctgct cggctgcctg actgcctgtt ggtggccgta
     4381 tctgaatcaa tcggtcgcac ccggttcttt accttggtat gcatcatgga cgttcaaaac
     4441 catcttagcc ctgattcccg taaccgcagg ttatctgttt aaatggaaac aataccggca
     4501 gcgcaaaaca aagccgtaag cccgtccttt tcagacggca tctccggtca gactgtcaac
     4561 aattccgata aaatgctata ctcgcgcccg ttgccgcgcc gtccgaaacc gccctttggg
     4621 aaagcagaaa tgatcagcaa acaagaatac caagcccaag ccgctcaagg ctacaaccgc
     4681 atcccgctcg tgcaagaact ccttgccgat ttggatacgc cgctttccct ctatctcaaa
     4741 ctcgccaacc gcccctatac ctacctgctc gaatccgttg tcggtggcga acgtttcggc
     4801 cgctattctt ttatcggcct gccttgcagc cactatctca aagccagcgg caaacacgtc
     4861 gatgtttatc aaaacggcga aattgtcgag caacacgacg gcaaccccct gccctttatc
     4921 gaagccttcc acaaccgctt caaaacaccc gaaatcccaa gcctgccgcg ctttaccggc
     4981 ggactggtcg gctacttcgg ttacgaaacc atctacaatt ttgaacactt cgcccaccgc
     5041 ctgaaaaaca ccaccaaagc cgacccgctc ggcacgcccg acatcctcct gatgctctcg
     5101 caagagcttg cagtagtgga taacctaagc ggtaaaatct acctgattgt ttacgccgat
     5161 ccgtcgcagc ccgacggcta cgaacgcgca cgcgaacgcc tcgaagacat ccgtacacag
     5221 ttacgccaaa gttgcgccat cccgctttcg ctcggcagca aacacaccga agccgtcagc
     5281 gaattcggcg aagagccgtt caaagcctgc gttaacaaaa tcaaagacta catctttgca
     5341 ggcgactgca tgcaggttgt ccccagccag cgcatgagca tggaattcac cgacagctcg
     5401 ctcgccctct accgcgcctt gcgcacgctc aacccttcgc cttatctctt ctactacgat
     5461 ttcggcgatt tccacatcgt cggctcctcg cccgaaatcc tcgtccgccg cgaacgcgac
     5521 gatgtcatcg tccgccccat cgccggcacg cgcctgcgcg gcaaaacccc cgccgaagac
     5581 cttgccaacg aacaagattt gttaagcgat gccaaagaaa tcgccgaaca cgtcatgttg
     5641 attgacttag gacgcaacga cgtcggccgc atcagtaaaa ccggcgaagt caaagttacc
     5701 gacaaaatgg tgattgaaaa atactcccat gtaatgcaca tcgtttccaa cgtcgaaggc
     5761 cgtctgaaag acggcatgac caacatggac atcctcgccg ctaccttccc tgccggcaca
     5821 ctctccggcg cacccaaagt ccgcgccatg gaaatcatcg aagaagtcga accaagcaaa
     5881 cgcggcatct acggcggtgc cgtcggcgta tggggtttca acaacgacat ggatttggca
     5941 atcgccatcc gcaccgccgt agtaaaaaac aacacgctat acgtccaaag cggcgcgggc
     6001 gtggttgccg actccgatcc ggcctccgaa tggcaggaaa cacaaaacaa agcccgagcc
     6061 gtcatacacg ccgcgcagat ggtgcaggaa gggttggata aatgacttat gaaaaacttt
     6121 atgagcttcg ccaaacactc agaccgacta ccaaagacgg tctctataca gataatgaaa
     6181 aaagtcgaga aatcctaacg gttagatgga gcggcaacac agaaaatcct aaaaatttct
     6241 cagctgttgc tataggaatt aatccaagta aagcaaatga tgaaagaagc gacaaaaccc
     6301 ttacccaact tgcacgtttc ttggatatgt acggttttac caacttcaaa atgttaaata
     6361 ttttttccag ttactctaca cagcaaacag gaattagggc aaacacccaa accgattttt
     6421 ccaaatttaa aggatgtttg gaagatgctg atatgattat tcttgcatgg ggtacagacc
     6481 gcggtgctta taaggatgaa aaaaacagaa tactggaatt tctaaaagca gaaaaattta
     6541 tggaaaaagt attctgtatt tctgaaactg gtaattccag cgatacaaga catccgtcaa
     6601 gaattagtta tagctatcaa cttgtacaat ttgaagagtc agcatgaaaa acatatctct
     6661 ttctccgccc gccatgcttg gcatcctcgg cggcggacaa ttaggcagaa tgtttaccgt
     6721 tgccgccaaa accatgggct acaaagtaac cgttctcgac cccgatccgg acgcgccggc
     6781 agcagaattt gccgactgtc atttatgcgc gccgtttaac gaccaagctg ctttggacga
     6841 attggcaaaa tgcgcggcgg tgaccactga atttgaaaac gtcaatgccg atgcgatgcg
     6901 ttttctcgcc aaacacacca atgtttcccc cggcagcgac tgcgttgcca tcgcgcaaaa
     6961 ccgcattcag gaaaaggcat ggatacgcaa agcaggattg caaaccgcgc cgtatcaagc
     7021 aatttgcaaa gccgaagaca tcactgaaga aagcatacaa tttctgcccg gcatcctgaa
     7081 aaccgctaca ttgggctatg acggcaaagg ccaaatccgc gtcaaaacgg tggatgaact
     7141 caaagccgcg tttgccgaac accgcggcgt ggattgcgtt ttggaaaaaa tggtggactt
     7201 gcgcggcgaa atttccgtta tcgtatgccg tctgaacaat gacaacgtgc aaactttcga
     7261 tcctgccgaa aacattcacg aaaacggtat cctcgcctac tccatcgtcc cagcccgact
     7321 gagtgccgac attcagcaac aggcgcgaca aatggcgcag cgtttggccg atgaattgaa
     7381 ctacgtcggc gtattggcgg tagaaatatt tgttgtcggc gacacgcatg aattggtcgt
     7441 caacgaaatc gcgccgcgtc cgcacaattc cggccaccat accgtcgacg cctgcgcggc
     7501 agaccaattc cagcaacagg tccgcctgat gtgcaacctg ccacctgctg acaccaaatt
     7561 gctgagttct tgctgtatgg cgaatatttt gggcgacgtt tggcaggaag acggcggcga
     7621 accggattgg tttcccctgc aaagccggcc ggacgcgcac ctgcaccttt acggcaaaaa
     7681 aaccgcgcac aaagggcgga aaatgggaca ctttaccgtt ttaaccaccg attcggacac
     7741 cgcatttcaa gaagcaaaaa aactgcatca gtccctataa tccgaccaac ggcacagatg
     7801 ccgtctgaag ccgccgacat accgccatga gcctgctgac actgttacgc cccgccaccg
     7861 tgcaagactg caaagacatc ttcaaagtcc acctgcactc cgtccaatac acctgcatcc
     7921 tcagctacaa cgaacacgcc ctaaaagtat gggaaggctt gttaaacaca gaaagctacc
     7981 tgccgaccat ttcagatccc gacaaagcac tttgggttgc cgaatacaaa ggcaacatac
     8041 agggattttt ccaaatcgac tgccaagaag cacaactcga tgcgctttac gtccaccccc
     8101 tgttccacaa cctcggactg ggcactgccc tacttcatca ggcggaaacc atcgcccaca
     8161 aatccggttt gagctttctg aaactctacg catcgctcaa ctccgtcccg ttttaccttc
     8221 tcaaccgcta cgaatcgctc ggttcggcag tattgcagct tgaccccagc atcaaaatca
     8281 aatgcgaact gatgcgcaaa cacctctaat cccaccttat aaccaaaact gataatcttc
     8341 aaatcaaaca ttatttccac aagcgcagac agccgtataa agttgcccca tctaccaacc
     8401 gacaggacaa gcatatgaaa acctacgcac cggcactcta taccgcagcc ctgctcaccg
     8461 cctgcagccc cacagccgat tcaaaccatc cgtccggaca aaatgccccg gccaataccg
     8521 aatccgacgg aaaaaacatt accctgctca acgcctcata cgatgtggca cgggattttt
     8581 acaaagaata caacccctta tttatcaaaa cataccaatc cgaacacccc ggcacatccg
     8641 tcagcatcca acagtcccac ggcggctcca gcaaacaggc attatccgta gccaacggcc
     8701 ttcaagccga tgtcgtaacc atgaaccaat cctccgacat cgacctgctc gaaaaaaaag
     8761 gactggtaga aaaaggctgg caacaagccc tccccgacca cgccgcgccc tacaccagca
     8821 ctatggtttt ccttgtccga aaaaacaacc ccaaacagat ccgcgattgg aacgaccttg
     8881 ccaaagacgg cgttaacatc gtcatcgcca atcccaaaac ctcgggcaac ggacgctacg
     8941 ccttcctcgg cgcatacggt tacggtctga aaaccaccaa cggcaacgaa caggaagccc
     9001 aaaaactcgt cgcatccatc ctcaaaaaca cccccgtttt tgaaaacggc ggacgcgccg
     9061 ccaccaccac cttcacacaa cgcaacatcg gcgacgtact catcactttt gaaaacgaag
     9121 ccaactacgt cagcaaaaaa ctgacccaag gacagtttga aatcgtctat ccgagctaca
     9181 ccatttccgc cgaaagcccc gtcgccgtcg tcaacagcgt cgtcgcgaaa aaaggcacgc
     9241 aaaaaaccgc ccgcgcctat ctcgaatacc tttggagcga accggcgcaa gaactcgccg
     9301 cctcactcta cctgcgcccc cgcaaccccg aagtattggc aagacacaaa gcctacttcc
     9361 cagacttaga caccttctct cccgaagaaa aattcggcgg atgggacaac atcatgaaaa
     9421 cctacttcgc cgacggcggc atattcgacc gcctgaccgc acaaaaatga ccgctatgcc
     9481 gtctgaaccg cctttcagac ggcatttcac acatcaaaac agaaaaaccg cgcccaaaat
     9541 catcatcaca agacacaacg gcaaaccgga tacaaaaccc aacaccgccg ccaaaatgcc
     9601 gtctgaagcc gtcggcgcaa ccatccttat ctggggcata actttcctta accatccctt
     9661 ttgacagcca aataaacagt gcttttgcct gtcagaaaca aaaccaatat tttgcagttc
     9721 gtatcggaac atttatagtg gattaacaaa aaccagtaca gcgt
//
LOCUS       DAXIDM010000069         9645 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000069 DAXIDM010000000
VERSION     DAXIDM010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9645
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.069"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..282
                     /locus_tag="ACFOAE_001444"
     CDS             <1..282
                     /locus_tag="ACFOAE_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003747967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFC6884910.1"
                     /translation="KDSPTFGKWVGEILSAENKRQLWVPEGFAHGFYVLSDEAEFVYK
                     CTDYYNPEAEHSLIWNDPTVGIDWPLQGEPNLSPKDLAGKVLAEAVTFG"
     gene            338..1459
                     /locus_tag="ACFOAE_001445"
     CDS             338..1459
                     /locus_tag="ACFOAE_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stealth family protein"
                     /protein_id="HFC6884911.1"
                     /translation="MNLNKIRKFFRESHIFFRDFLNKRFPPYNVEQPIPETEEFTLIN
                     ADANLASLTENVLPNFPIDVVFTWVDNTDKAWQEQYYRTLQPIDQEDIGLYATDPARF
                     SNHNELFYSVQAVQKFMPWVRNIFIVTADQKPKWLDENIHSKIKLINHSQLIDAKYLP
                     TFNSHVIEANLYKIPDLSEHFIYFNDDVFVARPLMPNHFFENNGLASLFVANKSFQKM
                     RQRGLITPTLTASEHALKLLKRHYPTININTPLVHTYVPLRKTSFQKAWSLFEDEINS
                     FLNNKVRHNSELNMASFLIPWLMYLDGYATPKREICYYFNIRSSHAQTQYKKLLFEKE
                     HLHMPHSFCINDSSSNNADKNYALHFRNFMDTYFEIETE"
     gene            1504..3528
                     /locus_tag="ACFOAE_001446"
     CDS             1504..3528
                     /locus_tag="ACFOAE_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="HFC6884912.1"
                     /translation="MIFSTFGLFKQRLLLTKFLDKISTDKTALFWGKKHPKRRKLAHI
                     LRLSLLNLEDGFLRSLGLGVAGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSE
                     TLAQARQAMDFILQHHLSKYNHAPELSDDHPLRSPSKPETVLIIDQTFGDMAIQYGGA
                     DASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLAQQHRVHLLAEDINPIS
                     LLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPEINRLVQTQRRAT
                     RNLLQLFAAAYLQYSRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWK
                     RAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARILAWGNGKEAIVRFAEQHHIPLLR
                     MEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
                     QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTV
                     RERNPNAYIIYKPHPDVVSGNRIGHISPEDAARYADQTAEQADILTCLQYADEIHTMT
                     SLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELWQLIAGTLIHYPDYI
                     HPETHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK"
     gene            3665..4924
                     /locus_tag="ACFOAE_001447"
     CDS             3665..4924
                     /locus_tag="ACFOAE_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis protein"
                     /protein_id="HFC6884913.1"
                     /translation="MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKT
                     VHKFNFNAGDDYFYPPTQAHTVVFNDNYDAFPEFLQEYITQHHIQAVVCFGDTRPYHV
                     IAKRIANENQASFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
                     KAPTPVHGGFTPMAKNAIRYYIELFRNLRKYPDYIHHRAPNAGHYLKPWSLSILKRLN
                     YYIEDIQIAKRVEAGKYGKFFIVPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAP
                     ADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELKGRVIYVHDVPLPVFLRHGLGMVTI
                     NSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLN
                     VTQINGNFYSQVFFPNKKTSDSSTPAT"
     gene            5291..6697
                     /locus_tag="ACFOAE_001448"
     CDS             5291..6697
                     /locus_tag="ACFOAE_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFC6884914.1"
                     /translation="MTAAPDILYRQAAALLEQSNTAQALPLLQQAAEQGYAEAAFVLG
                     NHLLQNGQPEQALSWLEAAAAQRHPKALFSLLQQREHNGTPTGQLLNDYAWLGEQGHS
                     EAQLILMRYHAQRNDPQSLYWAELAAARYAAPAYYHLARHHQRQGDVETAIEQYEKAA
                     ALGVTAACWQLGQIYFYGTGVSPNHAQAEHYLEPAAQAGHIAAQTLLADLLAAQRKPE
                     ALEWYRRAADKEQAEAQSKLAQYALTGELSERDPFQAARYAKAAAEKDHPEALKIMGD
                     LYRYGLGIKADNHIAHDYYHRAAALGSAAAAQKLISDAALYHPQQYEQIKTAALQQQQ
                     TETIYRLAEAQACAIGRPADYNAARKNYMEAAGFHHKNAAAALGRIYHYGLGTAQDPR
                     AAAHWYAIAAEQNHPSAQYHLACFYYHGQGVGCHVPTACYWLQAAIGNGHTSAESLIS
                     LLEQWRREAHHAIGQKAV"
     gene            6915..8129
                     /gene="gltS"
                     /locus_tag="ACFOAE_001449"
     CDS             6915..8129
                     /gene="gltS"
                     /locus_tag="ACFOAE_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HFC6884915.1"
                     /translation="MEWEFNSYYTLIAATLVLLVGKFLVQKIKFLRDFNIPEPVAGGL
                     VAAIILFALHEAYGVSFKFEKPLQNAFMLIFFTSIGLSADFSRLKAGGLPLVVFTAIV
                     GGFILVQNFVGVGLATALGLDPLIGLITGSVSLTGGHGTSGAWGPNFETQYGLVGATG
                     LGIASATFGLVFGGLIGGPVARRLINKMGRKPVENKKQDQDDNADDVFEQAKRTRLIT
                     AESAVETLAMFAACLAFAEIMDGFDKEYLFDLPKFVWCLFGGVVIRNILTAAFKVNMF
                     DRAIDVFGNASLSLFLAMALLNLKLWELTGLAGPVTIILAVQTVVMVLYATFVTYVFM
                     GRDYDAAVLAAGHCGFGLGATPTAVANMQSVTHTFGASHKAFLIVPMVGAFFVDLINA
                     AILTGFVNFFKG"
     gene            8228..9244
                     /locus_tag="ACFOAE_001450"
     CDS             8228..9244
                     /locus_tag="ACFOAE_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HFC6884916.1"
                     /translation="MYRKLIALPFALLLAACGREEPPKALECANPAVLQGIRGNIQET
                     LTQEARSFAREDGRQFVDADKIIAAAYGLAFSLEHASETQEGGRTFCIADLNITVPSE
                     TLADAKANSPLLYGETALSDIVRQKTGGNVEFKDGVLTAAVRFLPVKDGQTAFVDNTV
                     GMAAQTLSVALLPYGVKSIVMIDGKAVKKEDAVRILSGKAREEEPSKPTPEDILEHNA
                     AGGDADVPQAAEGAPEPEILHPDDGERADTVTVSRGEVEEARVQNQRAESEITKLWGG
                     LDTDVQKELVGEQRKWAQEKISNCRQAAAQADRQEYAEYLKLQCDTRMTRERIQYLRG
                     YSID"
     gene            9255..9452
                     /locus_tag="ACFOAE_001451"
     CDS             9255..9452
                     /locus_tag="ACFOAE_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884917.1"
                     /translation="MNTVPKSRIPVKPLPEKTTDEAKVEKWRQLGAEHGLSGEWAVAV
                     RLGENGFTEEQMENIANLFGR"
     gene            9470..9619
                     /locus_tag="ACFOAE_001452"
     CDS             9470..9619
                     /locus_tag="ACFOAE_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884918.1"
                     /translation="MPSETLLSVSDGILTNTVRRRKTAGFSCVAYADVSTRRTIYKAL
                     PYVPS"
BASE COUNT         2589 a         2700 c         2113 g         2243 t
ORIGIN      
        1 aaagactccc ccactttcgg caaatgggta ggcgagattc tgtccgcaga aaacaaacgc
       61 caactgtggg tacccgaagg tttcgcacac ggcttctatg tactgagcga tgaagccgag
      121 ttcgtctata aatgcacaga ctattacaac cctgaagccg aacactcact aatttggaat
      181 gatccgaccg tcggcatcga ctggccgcta caaggcgagc cgaacctgtc gcctaaagac
      241 ttggcaggca aagtattggc cgaagcagta acgtttggat aacttcaaaa cataacagaa
      301 tcaactgttt ctattttgta gtattagaaa gtttcaaatg aatttaaata aaattagaaa
      361 attttttaga gagtcccata ttttctttag ggattttcta aataaacgct ttcctcctta
      421 taatgtagaa cagcctattc ctgaaactga agaattcact ctgatcaatg cagatgccaa
      481 tcttgcatca ctcacagaaa acgttttgcc aaactttccc atcgatgttg tttttacttg
      541 ggtcgacaat accgataaag catggcaaga acagtattac cgtaccctgc agcccatcga
      601 tcaggaagat atcggcctgt atgcgaccga ccctgcccgc ttttccaacc ataatgaact
      661 tttttattca gtacaggccg tacaaaagtt tatgccgtgg gtccgcaata tttttattgt
      721 aacggcggat caaaaaccta aatggttaga tgaaaacatc cattctaaaa ttaaattaat
      781 caatcattcg caacttattg atgccaaata cttaccaacg ttcaattccc acgtcattga
      841 agcaaactta tataaaattc cagatttaag tgaacatttt atttatttca atgatgatgt
      901 tttcgttgca agaccactga tgcctaacca cttttttgaa aataatggtt tggcttccct
      961 atttgttgcc aataaaagtt ttcaaaaaat gcgtcaacgg ggtctaatca cgccgacatt
     1021 gaccgcatca gaacacgcat taaagctctt aaaaagacat tatccgacaa ttaatatcaa
     1081 tacaccgtta gtacatactt acgttccgct acggaaaaca tcctttcaaa aagcatggtc
     1141 attatttgaa gatgaaataa attctttcct aaataacaag gttcgccata attctgaact
     1201 taatatggcc agtttcttga taccctggtt gatgtacctt gacggatatg caacaccgaa
     1261 acgtgaaatt tgctactatt tcaatatacg cagttcacac gcccagactc aatataaaaa
     1321 attattattt gaaaaagaac atcttcatat gccccactcc ttctgcatta acgattcaag
     1381 cagtaataat gcggataaaa actatgccct tcatttccgt aattttatgg acacttactt
     1441 tgaaatagag acagaataaa tttttacatt aatgatactt aatagataac ataataattt
     1501 aaaatgattt tttcaacatt cggcctattt aaacaacgtc tcttgctaac caaattttta
     1561 gacaaaattt caacggataa gaccgcatta ttttggggca agaaacatcc caaacgtaga
     1621 aaattagcac atatcttaag attgtccttg ctcaatcttg aagacggctt tttacgatcg
     1681 ctcggactgg gtgtcgccgg ctatcctccc tattccatcg tctatgacga catcggcatc
     1741 tactacgaca ccacccgtcc ttcgcgtttg gaacaactga ttcttgccgc cgataccatg
     1801 ccgtctgaaa ccttggctca ggcgcggcag gcgatggatt tcatcctgca acaccacctg
     1861 tccaaataca accacgcgcc cgaactttca gacgatcatc ctttacgctc cccatccaag
     1921 cctgaaactg tcctcattat cgaccaaacc ttcggcgata tggccatcca atatggcggc
     1981 gcagacgcct ctacgtttga actgatgttt cagacggcct tgaatgaaaa cccgcaagcc
     2041 gatatctggg taaaaaccca tcccgatgtt ttgtgcggca aaaaacaagg ctatctgacc
     2101 caactggcgc agcaacaccg cgtccatctt ctggcagaag acatcaaccc gatttctttg
     2161 ttgcaaaacg tcgataaagt ttattgcgtt acctcgcaaa tgggttttga ggcacttttg
     2221 tgcggcaagc cgctgaccac cttcggcctg ccgtggtatg ccggatgggg tgtaagcgac
     2281 gaccgccatc ctgaaatcaa ccgccttgtt caaacccaac gccgcgccac ccgcaacttg
     2341 ctgcagctct tcgccgcagc ctatctgcaa tacagccgct acctcaaccc caataccggc
     2401 gaagcaggca gcctctttga tgtcatcgac tatctggcga cggtcaaacg taaaaacgac
     2461 aaattgcgtg gcgagttata ttgcgtcggt atgtctttgt ggaaacgcgc ggttgccaaa
     2521 ccgttcttta acgtaccctc ttgccgtctg aaatttatct cttccaccca aaaactggca
     2581 agggtcaaac tgtccgacga tgcacgcatc ctggcttggg gcaacggcaa agaggccatc
     2641 gtccgctttg ccgaacaaca ccacatcccc ctgctgcgca tggaagacgg ctttatccgc
     2701 tcggtcggac tcggctccaa cttagtgccg ccgctgtcgc tcgttaccga cgatatgagc
     2761 atttatttca atgccgaaac cccgtcccgt cttgaataca tcctacaaaa ccaaaacttc
     2821 gacgatcaag actttcagac ggccttgaag ctgcaaaaaa tgctgaccga aaaccacatc
     2881 agtaaataca acgtcggcag ctcagacttc accgccccgt caaccgacaa aaccgtgatc
     2941 ctcgttcccg gccaggttga agatgatgcg tctatccgct acggttcgcc ccaaatctac
     3001 cgcaatctgg atttgctccg taccgtacgc gaacgaaacc ccaatgccta tatcatctac
     3061 aaaccgcatc ccgatgtagt cagcggtaac cgcatcggcc atatttcccc tgaagatgct
     3121 gcacgatatg ccgaccaaac cgccgaacaa gccgacatcc tgacctgtct ccaatacgca
     3181 gacgaaatac ataccatgac ttcgctgacc ggttttgaag ccttgttgcg cggcaaaaaa
     3241 gtcagctgct acggcctgcc tttttacgca ggctgggggc ttacccaaga tctgctcccc
     3301 atcccgcgcc gtagccgcag acttgagctt tggcagctga ttgccggcac gctcatccac
     3361 tatcccgact acatccaccc cgaaacccat caggccataa atgcagaaac cgcagcccaa
     3421 atcctgatac gacaaaaaaa tatgcaaaaa aacaacaacg gattacatcg cgggtgcttt
     3481 gccaaaaaat taggtaaaat caaacaacta tatcgatctt tcaaataaat accatcaaag
     3541 ttaacgatgc gtcataaact tgcctctatt gcggcatcat tgcctttgca tcgttaattc
     3601 tcttggcgta tgcttgaaag ttcaacctaa aactattaca taaaaaacaa aaccacattg
     3661 caacatgaaa cagaccgtcc tcaaaaataa cctgcaaaac ctgcttgaaa gcgcagaaaa
     3721 tatcctgctg cttcaaggcc ctgtcggcga tttttttctg cgccttgccg actggctgac
     3781 tgcaaacggc aaaaccgtac ataaattcaa ctttaatgca ggcgacgact atttttatcc
     3841 gcccactcaa gcgcataccg ttgtttttaa cgacaactac gatgcctttc ctgagttttt
     3901 gcaagaatac atcactcaac atcacatcca ggccgttgtc tgctttggcg acacacgccc
     3961 ttatcacgtc attgcaaaac gcattgcaaa cgaaaaccaa gccagtttct gggcgtttga
     4021 agaaggctat ttccgcccct actacatcac cttagaaaaa gacggcgtca acgcattttc
     4081 cccgttgccg cgccgtgccg acttttttct tgaacaattc cctaagcttg cccagcaaga
     4141 atataaagcg ccaacgccgg tacacggcgg ttttacgccc atggcaaaaa acgctatccg
     4201 ttactatatc gagttgttcc gcaatctacg caaatacccc gactacatcc accaccgcgc
     4261 acccaatgcc ggccattacc tcaaaccgtg gtcgctctcc atcctcaagc gtttgaacta
     4321 ctatattgaa gacatccaaa tcgccaaacg tgtggaagca ggcaaatacg gcaagttttt
     4381 tattgttccc ttgcaggtat tcaacgacag ccaagtccgt atccattgcg actttcccag
     4441 cgtccgcagc ttcctgctcc atgttttgag ttcatttgcc gagcacgcgc ctgccgatac
     4501 caacatcatc atcaagcatc atccgatgga ccgcggtttt atcgactact ggcgcgacat
     4561 taaacgcttt atcaaagaac accccgaact caaaggccgc gtgatttatg tccatgatgt
     4621 ccccctgccc gttttcctgc gccacggtct cggcatggtc accatcaaca gcaccagcgg
     4681 cctgtccgga ctgattcaca atatgccagt taaggttctc ggccgtgcct attatgatat
     4741 tcccggcatt actgaccaaa ataccttggc agaattttgg aatcatccga caccgcctga
     4801 caaagagctg ttccatgcct accgaatgta ccacctcaac gtgacccaaa ttaacggcaa
     4861 cttctacagt caggtctttt ttcctaacaa aaaaacctcc gactcttcca ctccagcaac
     4921 ctgacttagc aaaaataatt caggccgtct gaaaacattt cagacggcct gaaacaatca
     4981 ataccttagc tactgccatg taaataaaac acaaaaacct gcatttatca ttaacaataa
     5041 attacaaaaa cagtataatg accgagctgc catgagcgca taccgactca acctgagccc
     5101 tttgtaacac acaaaatatg gatatatccc taggcaaaac aatataacaa gccaaacatc
     5161 ctaaagataa gccggcaagg caacacactc tacaaaaccg tgccaagcaa tatttttaca
     5221 aagccctcaa ccggtatcgc cgcccatatg ccgcagcatc cgtcttccac tttatatccg
     5281 cccgcaaacc atgaccgccg ctcctgacat cctctaccgg caagccgccg cccttttgga
     5341 acaatccaat accgcccaag ccctgcccct gttgcaacag gcggcagagc aaggttatgc
     5401 ggaagctgct ttcgtattgg gcaaccatct gctgcaaaac ggccaaccgg agcaggcact
     5461 ttcatggttg gaagccgccg cggcccaacg ccatcccaaa gcactcttct ccctgctgca
     5521 acaacgcgaa cacaacggca ccccgaccgg acagcttctc aacgactatg cctggctggg
     5581 tgagcagggg cactcagaag cccaattaat cctcatgcgt taccacgcgc aacgcaacga
     5641 tccacaatcg ctctactggg cggaacttgc tgccgcccga tatgccgcac ctgcgtatta
     5701 ccatctggca cgccatcatc aacgccaagg cgacgttgaa acagccatcg aacaatacga
     5761 aaaagcggca gcactcggcg taactgccgc ctgctggcaa cttggtcaaa tctacttcta
     5821 cggtacaggt gtcagcccca accacgcaca agccgaacac tatctcgaac cagccgcaca
     5881 agccggccac atcgccgcac aaacgctgct ggctgacctt cttgccgccc aacgcaaacc
     5941 tgaagccttg gaatggtatc gtcgtgccgc cgataaggaa caagcggaag cacagtctaa
     6001 gctggcccaa tacgccctga ccggcgaact ttccgaacgc gatccgttcc aagcggcacg
     6061 atatgccaaa gccgctgccg agaaagacca tcctgaagcc ctgaaaatca tgggcgacct
     6121 ctaccgctac ggcctcggca tcaaagctga caaccatatc gcgcacgatt actaccaccg
     6181 tgctgccgcg ctgggttctg ccgccgcagc acaaaaactc atcagcgacg ccgcgctgta
     6241 ccatccgcaa caatacgaac aaatcaaaac tgccgccctg caacaacaac aaaccgaaac
     6301 catctaccgt ttggcggaag cacaagcctg cgccatcggc cgtcccgccg actacaatgc
     6361 cgcgcgaaaa aattacatgg aagctgccgg gttccaccat aaaaacgcag cggcagcctt
     6421 aggccgcatc taccattacg gcctcggtac ggcgcaagat cctcgggcgg ctgcacactg
     6481 gtacgccatt gctgccgaac aaaaccaccc ttccgcccaa taccacctcg cctgttttta
     6541 ctatcacggg caaggtgtcg gctgtcatgt tccgaccgcc tgctactggc tgcaggccgc
     6601 catcggcaac ggccacactt cggccgaatc attaatatcc ctattagaac aatggcgacg
     6661 cgaagcacac catgccatcg gacaaaaggc cgtctgaaaa gatttacact cgcatttttt
     6721 gacaatcttt aactattccc ctaatatttg ccagttattt ttcacggaca cgccattgtt
     6781 ttcatttctt tctgaaaaca ccttgtccgc gcatcaatac catgacactc ggcggataac
     6841 gccaagcgtt gaaacacact acatccggaa caaaaacgga tgctcggaaa aatatttcta
     6901 ggaggtgaaa caacatggaa tgggaattca acagttatta cacactgatt gccgccacgc
     6961 tcgtgttgct ggttggtaaa tttctggttc aaaaaatcaa attcttacga gacttcaata
     7021 ttcccgagcc ggtcgctggc ggtttggttg ccgcgattat cctgtttgcg ctgcacgagg
     7081 cgtacggcgt gagcttcaaa tttgagaaac cgctgcaaaa tgcgtttatg ctgattttct
     7141 tcacgtccat cggcttgagc gcggattttt cccgtttgaa ggcgggcggt ttgccgctgg
     7201 tggtttttac cgcgattgtg ggcggattta tcttggtgca aaactttgtc ggggtcggac
     7261 tggctacggc tttgggtttg gacccgctca tcggtctgat taccggttcg gtgtcgctga
     7321 cgggcggaca cggtacgtca ggtgcgtggg gacctaattt tgaaacgcaa tacggcttgg
     7381 tcggcgcaac cggtttgggt attgcatcgg ctactttcgg gctggtgttc ggcggcctga
     7441 tcggcgggcc ggttgcgcgc cgcctgatca acaaaatggg ccgcaaaccg gttgaaaaca
     7501 aaaaacagga tcaggacgac aacgcggacg acgtgttcga gcaggcaaaa cgcacccgcc
     7561 tgattacggc ggaatctgcc gttgaaacgc ttgccatgtt tgccgcgtgt ttggcgtttg
     7621 ccgagattat ggacggcttc gacaaagaat atctgttcga cctgcccaaa ttcgtgtggt
     7681 gtctgtttgg cggcgtggtc atccgcaaca tcctcactgc cgcattcaag gtcaatatgt
     7741 ttgaccgcgc catcgacgtc ttcggtaacg cctccctgtc cctcttcctt gccatggctc
     7801 ttctgaacct gaaactgtgg gaattgaccg gtttggcagg ccctgtaacc atcatcttgg
     7861 ctgtacaaac cgtggtgatg gttttgtacg cgacttttgt tacctatgtc tttatggggc
     7921 gcgactatga tgcggcagta ttggctgccg gccattgcgg tttcggcttg ggtgcaacgc
     7981 cgacggcggt ggcaaatatg cagtccgtca cgcatacttt cggcgcgtcg cataaggcgt
     8041 ttttgattgt gcctatggtc ggcgcgttct tcgtcgattt gattaatgcc gcgattctca
     8101 ccggttttgt gaatttcttt aaaggctgat tttccgcctt tccgacaaag cacctgcaag
     8161 gtttaccgcc tgcaggtgct tttgctatga tagccgctat cggtctgcac cgtttggaag
     8221 gaacatcatg tatcggaaac tcattgcgct gccgtttgcc ctgctgcttg ccgcttgcgg
     8281 cagggaagaa ccgcccaagg cattggaatg cgccaacccc gccgtgttgc aaggcatacg
     8341 cggcaatatt caggaaacgc tcacgcagga agcgcgttct ttcgcgcgcg aagacggcag
     8401 gcagtttgtc gatgccgaca aaattatcgc cgccgcctac ggtttggcgt tttctttgga
     8461 acacgcttcg gaaacgcagg aaggcgggcg cacgttctgt atcgccgatt tgaacattac
     8521 cgtgccgtct gaaacgcttg ccgatgccaa ggcaaacagc cccctgctgt acggggaaac
     8581 cgctttgtcg gatattgtgc ggcagaagac gggcggcaat gtcgagttta aagacggcgt
     8641 attgacggca gccgtccgct tcctgcccgt caaagacggt cagacggcat ttgtcgacaa
     8701 cacggtcggt atggcggcgc aaacgctgtc tgtcgcgttg ctgccttacg gcgtgaagag
     8761 catcgtgatg atagacggca aggcggtaaa aaaagaagac gcggtcagga ttttgagcgg
     8821 aaaagcccgt gaagaagaac cgtccaaacc cacgcccgaa gacattttgg aacataatgc
     8881 cgccggaggg gatgcagacg taccccaagc cgcagaaggc gcgcccgaac cggaaatcct
     8941 gcatcctgac gacggcgagc gtgccgatac cgttaccgta tcacggggcg aagtggaaga
     9001 ggcgcgcgta caaaaccagc gtgcggaatc cgaaattacc aaactttggg gaggactcga
     9061 taccgacgtg caaaaagagt tggtcggcga acaacgcaag tgggcgcagg aaaaaatcag
     9121 caactgccga caagccgccg cgcaggcaga ccggcaggaa tacgccgaat acctcaagct
     9181 gcaatgcgac acgcggatga cgcgcgaacg gatacagtat cttcgcggct attccatcga
     9241 ttaggggcaa accgatgaat accgtcccaa aaagcaggat tcccgtcaaa ccgctgcccg
     9301 aaaaaaccac agacgaagcc aaagtcgaaa aatggcggca gctcggtgcg gaacacggtt
     9361 tgtcgggcga atgggcagtt gccgtcagat tgggcgaaaa cggttttacc gaagaacaga
     9421 tggaaaatat cgccaacctg ttcggcagat aaagagaaaa ttgacggaaa tgccgtctga
     9481 aaccctgtta tcggtttcag acggcatttt gaccaatacg gtacgcaggc gcaaaacagc
     9541 cggcttttcc tgtgttgcct atgctgatgt ttcaacacgc aggacgatat ataaagcgtt
     9601 gccctatgtg ccgtcctgat tcggaaaggg ttacgcccct cctaa
//
LOCUS       DAXIDM010000070         9429 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000070 DAXIDM010000000
VERSION     DAXIDM010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9429
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.070"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(110..1027)
                     /gene="thrB"
                     /locus_tag="ACFOAE_001453"
     CDS             complement(110..1027)
                     /gene="thrB"
                     /locus_tag="ACFOAE_001453"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HFC6884919.1"
                     /translation="MSVYTSVSDDEMRGFLSGYDLGEFVSLQGIAQGITNSNYFLTTT
                     SGRYVLTVFEVLKQEELPFFLELNRHLSMKGVAVAAPVARKDGRLDSVLAGKPACLVA
                     CLKGSDTALPTAEQCFHTGAMLAKMHLAAADFPLEMENPRYDAWWTEACTRLLPVLSQ
                     DDAALLCSEIDALKDNLGNHLPSGIIHADLFKDNVLLDGGQVSGFIDFYYACRGNFMY
                     DLAIAVNDWARTADNKLDEALKKVFIGGYEGVRPLSAEEKAYFPTAQRAGCIRFWVSR
                     LLDFHFPQAGEMTFIKDPNAFRNLLLSLD"
     gene            complement(1064..1792)
                     /gene="ubiG"
                     /locus_tag="ACFOAE_001454"
     CDS             complement(1064..1792)
                     /gene="ubiG"
                     /locus_tag="ACFOAE_001454"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="HFC6884920.1"
                     /translation="MGGKMSDKKYNVDEGEIAKFSRIADKWWDKSGEFKTLHDINPLR
                     LDYIDGHADLCGKRVLDVGCGGGILAESMARRGAAFVKGIDMAEQSLETARLHAALNN
                     VADIEYECIRVEDLAEAEPHSFDVVTCMEMMEHVPDPAAIVRACAKLVKPDGMVFFST
                     INKNPKSYLHLIVAAEYLLKFVPKGTHDWKKFIAPAELARMCRQAGLDVADTKGMTYH
                     VLSQTYALCDSTDVNYMFACRPAF"
     gene            1944..3185
                     /locus_tag="ACFOAE_001455"
     CDS             1944..3185
                     /locus_tag="ACFOAE_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015173 - aromatic amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015801 - aromatic amino acid transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter"
                     /protein_id="HFC6884921.1"
                     /translation="MPTKTPSLFGCAMIIAGTVIGAGMLANPTATSGVWFTGSLAVLL
                     YTWFSMLSSGLMILEVNTHYPHGASFDTMVKDLLGRGWNIINGIAVAFVLYLLTYAYI
                     FVGGDLTAKGIGNALGGNVSLTVGQLVFFGILAFCVWASARLVDRFTSVLIGGMVLTF
                     IWATGGLIADAKMPVLFDTQAPVGTNYWIYAATALPVCLASFGFHGNVSSLLKYFKGD
                     APKVAKSIWTGTLIALVIYVLWQTAIQGNLPRNEFAPVIAAEGQVSVLIETLSKFAQT
                     GNMDKILSLFSYMAIATSFLGVTLGLFDYIADIFKWNDSVSGRTKTAALTFLPPLISC
                     LLFPTGFVTAIGYVGLAATVWTGIIPAMLLYRSRKKFGAGKTYKVYGGLWLMVWVFLF
                     GIVNIAAQVLSQMELVPVFKG"
     gene            3193..3324
                     /locus_tag="ACFOAE_001456"
     CDS             3193..3324
                     /locus_tag="ACFOAE_001456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884922.1"
                     /translation="MPSEARRRLQTALPQQTATVFRHTAHYPAPHAQIPPRQTGTQP"
     gene            3335..3904
                     /locus_tag="ACFOAE_001457"
     CDS             3335..3904
                     /locus_tag="ACFOAE_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC6884923.1"
                     /translation="MKLKIDIATNNFKHGGGTERYTLDLVKGLNRQNITPAVYATKFD
                     HGIPEYAMIEPHLVDQHRTLKKLRSFLFSSRLAQTRKNSAAKLIACHHADYADLLICG
                     GTHLGYLHHMAQKPNLLDRLAIRRNRSNYATAKLIMAHSHMMRRELVGLYGVPPERIQ
                     VAPPRRYGTLLPATRRNCRPARQIRLCRL"
     gene            3915..4388
                     /locus_tag="ACFOAE_001458"
     CDS             3915..4388
                     /locus_tag="ACFOAE_001458"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC6884924.1"
                     /translation="MFPSTGHTRKGLELLADFFEHTGLPVKLAVVGSPLPRPMKNVVG
                     LGFCTDMPELYRAADFTIMASLYEPFGLVGVESVLCGTRVVLSENMACTEVMNEEAGF
                     FFSRQNPETLAQAVAQAVSLKKQGGHRLSDPMRALNYNPSLSHHIDRLTDILASV"
     gene            complement(4455..6107)
                     /locus_tag="ACFOAE_001459"
     CDS             complement(4455..6107)
                     /locus_tag="ACFOAE_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFC6884925.1"
                     /translation="MVAYVFLFLFVTAALVLIIRSHYRWTYFFASALFVFLAGGMLML
                     TAQWQRALNFASVWFVVLILFHRLKIHYYKQPLLISDFLLIADWRNWETLFHYKEAVI
                     GMAGLLALAAYAVFGWSGADALGLPWRWAGTVLFAAAFVSMRHFSKHPGAVKTWLDSL
                     PDDGRDVFLNLPMSCRAVFFQVPVFEGDGEAFAKQMPSETQPYGMSDEKPDIVVTLME
                     STLDPHCFDFAAAKIPDLKMFGRQEDTVFSSPLRVHTFGGATWKSEFAFLAGVPSTDF
                     GALASGVFYSVVPHLQTGFVRNLREHGYFCVALSPFTKGNYNAKAAYDHFGFNLMFQP
                     QDLGYPAPMGKNLWHISSEEMMQYARMILEKRHPDLENVRQPMFVYVLTMKEHGPYRT
                     DTDNVFDLDAPDLNAKTVSALNDYIGRIADLDKAVESFDRYLHECGKPFVFGYFGDHQ
                     VPFEGVSVRKKWDYAQPDYVTQFAVRSNIAGGFVQRQDFLDLAFAGGVLMEAAGLEAK
                     DGFMRANMAMRGLCGGGLEDCPNRKLVGDYRNYLYDVLKIAS"
     gene            6277..6546
                     /locus_tag="ACFOAE_001460"
     CDS             6277..6546
                     /locus_tag="ACFOAE_001460"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884926.1"
                     /translation="MNYKIYDGAKIIKKENLSIGDYSQIDDFVFFNCGEKSILGSFVH
                     ISSFTSIIGGGEFYMDHFSGLSAGCRIITGSDDFMGGVNQSNSPI"
     gene            6503..6844
                     /locus_tag="ACFOAE_001461"
     CDS             6503..6844
                     /locus_tag="ACFOAE_001461"
                     /inference="COORDINATES: protein motif:HMM:NF025953.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFC6884927.1"
                     /translation="MILWGGLTNPTVPSKYTNVKKSSVRIGKHAILGTNVTVLPGVTI
                     GDGVAVGAGAIVRKNLEPWTIYVGVDCKPLKRRSQDKILELEKHLVAEFNLDLCPIIP
                     SPTRPNPKETR"
     gene            6841..7404
                     /gene="gmhB"
                     /locus_tag="ACFOAE_001462"
     CDS             6841..7404
                     /gene="gmhB"
                     /locus_tag="ACFOAE_001462"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFC6884928.1"
                     /translation="MKLIILDRDGVINRDRDDFVKSADEWIPVEGSMDAVAFLTQAGC
                     TVAVATNQSGIGRKYFTVQDLTEMHAKMHRLIRQAGGEIDGIWFCPHTGADGCGCRKP
                     KPGMIEDILERFNAQASETWLVGDSLRDLQAIDAVGGKPALVLTGKGKKTLSQHGHEL
                     PEHTQVFDTLLDFSQYIMQENAAPQAD"
     gene            7434..8177
                     /locus_tag="ACFOAE_001463"
     CDS             7434..8177
                     /locus_tag="ACFOAE_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFC6884929.1"
                     /translation="MLIIRNLIYWLILCSSLIFLFPFMLLASPFQDGAHKMARIWVGI
                     LNWSLKHIVGLKYRIIGAEHIPDRPAVICAKHQSGWETLALQDIFPPQVYVAKRELFK
                     IPFFGWGLKLVKTIGIDRSNRREANEQLIKQGLARKNEGYWITIFPEGTRLAPGKRGK
                     YKLGGARMAKMFEMDIVPVALNSGEFWPKNSFLKYPGEITVVICPTIPYASGSEAELM
                     EKCEHLIETQQPLISGAGPFAAKMPSETA"
     gene            8174..8866
                     /locus_tag="ACFOAE_001464"
     CDS             8174..8866
                     /locus_tag="ACFOAE_001464"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HFC6884930.1"
                     /translation="MTAFVHTLSDGMELTVEIKRRAKKNLIIRPAGTHTVRISVPPCF
                     SVSALNRWLYENEAVLRQTLAKTPPPQTAENRLPESILFHGRQLAPTAHQDTQILLMP
                     SEIRVPEGAPEKQLALLRDFLERQAHSYLIPRLERHARTTQLFPASSSLTSAKTFWGV
                     CRKTTDIRLNWRLVGAPEYVADYVCIHELCHLAHPDHSPAFWELTRRFAPYTPEAKQW
                     LKIHGRELFALG"
     gene            8906..9091
                     /locus_tag="ACFOAE_001465"
     CDS             8906..9091
                     /locus_tag="ACFOAE_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884931.1"
                     /translation="MPEQAHARPIQTAMTLCRRFGAGWRHTRRLPRFISHRSSETRNP
                     PGPTCGMKRLSWREVFY"
BASE COUNT         2356 a         2916 c         2201 g         1956 t
ORIGIN      
        1 actataaaat ggaaaatacc cggctatcgt ctcattttcg ttttaatcag ccataaaaat
       61 gccgtctgaa accctttcag acggcatttc tgtcaaacgc cggacgcact caatccaaac
      121 tcaacagcag gttgcggaac gcgttcgggt ctttgataaa cgtcatctcg cccgcctgcg
      181 gaaaatgaaa gtccaacagg cgcgacaccc aaaaacggat gcagccggca cgttgggcgg
      241 tcgggaaata cgccttttct tcggcactca aggggcgcac gccctcataa ccgccgataa
      301 acaccttttt caacgcctca tccaacttat tgtccgccgt ccttgcccaa tcgttgaccg
      361 caatcgccaa gtcatacata aaattgcccc ggcaggcata atagaaatcg atgaaacccg
      421 atacctgacc gccgtcaagc aacacattgt ctttaaacaa atcggcatgg atgatgcccg
      481 aaggcagatg attgccgaga ttgtccttta acgcatcgat ttcggaacac agcagcgcgg
      541 catcgtcttg cgacaggacg ggcagcagcc gggtgcacgc ctccgtccac cacgcatcgt
      601 aacgcgggtt ttccatttcc aaagggaaat cggcggcggc aaggtgcatt ttggccagca
      661 tcgcaccggt atggaaacac tgctccgccg tcggcagcgc ggtatccgaa cctttcaggc
      721 aggcaaccaa acaagccggc ttgcccgcca aaacggaatc aagccggccg tctttgcgcg
      781 caaccggcgc ggcaaccgcc acgcccttca tactcaaatg ccggttaagc tccagaaaaa
      841 acggcagctc ttcctgtttc aacacttcaa acacggtcag cacataacgt cccgaagtcg
      901 tcgtcagaaa ataattgctg ttggtaatcc cctgcgcgat gccctgcagg gaaacaaatt
      961 cccccaaatc gtaaccgctc aggaagccgc gcatttcatc atcggaaaca ctggtataga
     1021 cagacatatc aactcacttg ctcaaaaacg ggcaaacccg ccgtcagaac gccggacggc
     1081 aggcaaacat ataattcaca tcggtcgaat cgcacagggc ataagtttgc gacaacacat
     1141 ggtaagtcat acccttcgta tccgccacat ccaagcctgc ctgacggcac attcgcgcca
     1201 gctcggcagg tgcgatgaat tttttccagt cgtgcgtgcc tttggggaca aacttcaaca
     1261 gatattccgc cgccacaatc agatgcaggt acgatttcgg gtttttattg atggtggaaa
     1321 aaaacaccat gccgtccggc ttgaccagct tggcacaagc acgcacgatg gcggcgggat
     1381 cggggacgtg ttccatcatt tccatgcacg ttaccacatc gaacgagtgc ggttccgcct
     1441 cggcaaggtc ttccacgcgg atacattcgt attcgatatc ggcgacattg ttcaaagccg
     1501 cgtgcaggcg ggcggtttcc aacgactgct ccgccatgtc gatgcccttt acaaacgccg
     1561 cgccgcgccg tgccatactt tccgccaaga tgccgccgcc gcagcccacg tccaaaaccc
     1621 gtttgccgca caaatccgcg tgcccgtcga tataatccag ccgcagcgga ttgatgtcgt
     1681 gcaaggtttt gaactcgccc gacttgtccc accatttgtc ggcaatccgg ctgaatttgg
     1741 cgatttcccc ctcatcgaca ttatattttt tgtcggacat tttccctccc atctgacgaa
     1801 ccgcccactc caaaacccaa gattatacta tggaacacaa tgccgtctga aagccttttc
     1861 gggcggcgcg gcgcaaatgc cttacaaatc cttacacttt acggcataat ggcggctcgc
     1921 tttttctggc agaaagacaa aatatgccca ccaaaacccc ttcactgttc ggctgcgcga
     1981 tgattatcgc cggcacggtc atcggcgcag gtatgctcgc caacccgacc gccacatccg
     2041 gcgtatggtt taccggctcg ctggccgtgt tgctgtacac ctggttttcc atgctctcca
     2101 gcggcctgat gattttggaa gtcaacaccc actaccccca cggcgcgagc ttcgacacca
     2161 tggttaaaga cctgctcgga cgcggctgga acatcatcaa cggtatcgcc gtcgccttcg
     2221 ttttatacct gcttacttac gcttatatct tcgtcggcgg cgacctgacc gccaaaggca
     2281 tcggcaacgc cttgggcggc aatgtttcgc ttaccgtcgg acaactcgtc ttcttcggca
     2341 tcctcgcctt ttgcgtatgg gcatccgcac gcttggtcga ccgcttcacc agcgtcctca
     2401 tcggcggcat ggtattaacc tttatttggg caaccggcgg cctgattgcc gatgccaaaa
     2461 tgcccgtcct gttcgacacc caagcccccg tcggcaccaa ctactggatt tacgccgcca
     2521 ccgccctgcc cgtctgcctt gcgtcattcg gtttccacgg caacgtctcc agcctgctca
     2581 aatactttaa aggcgacgcg cccaaagtgg ctaaatccat ctggacgggc acactgattg
     2641 cgctggtaat ttacgtcctc tggcaaaccg ccatccaagg caacctgccg cgcaacgagt
     2701 tcgcccccgt gattgccgcc gaagggcaag tctccgtcct catcgaaacc ctgtccaaat
     2761 tcgcccaaac cggcaatatg gataaaatat tgtccctatt ttcctacatg gcgatcgcca
     2821 cctcgttttt aggtgtaacg ctcggactct tcgactacat cgccgacatc ttcaaatgga
     2881 acgacagcgt gtccggccgc accaaaaccg ccgcgctgac cttcctgccg cctctaattt
     2941 cctgcctgct cttccccacc ggctttgtta ccgccatcgg ctacgtcggc ctggcggcaa
     3001 ccgtctggac aggcatcatc cccgccatgc tgctctaccg ttcgcgcaaa aaattcggcg
     3061 caggcaaaac ctataaagtt tacggcggct tgtggctgat ggtttgggtc ttccttttcg
     3121 gcatcgtcaa catcgccgca caggtattga gccaaatgga actcgtcccc gtatttaaag
     3181 gataaaggca aaatgccgtc tgaagcccgc cggcggcttc agacggcatt gccgcaacaa
     3241 acggcaaccg tattccggca cacagcgcat taccctgccc ctcacgcaca aatcccgccc
     3301 cgacaaaccg ggacgcaacc ataaaggaac aatgatgaag ctcaaaatag acattgcaac
     3361 caacaacttc aaacacggcg gcggcacgga acgctacaca ttggatttgg taaagggtct
     3421 gaacagacaa aacatcacac cggccgttta tgcgacgaaa tttgatcacg gcattcctga
     3481 atacgccatg atcgaacccc atcttgtcga tcaacaccgg acgctgaaaa aactacgctc
     3541 attcctcttt tcaagccggc tcgctcaaac cagaaaaaac agtgccgcca aactgattgc
     3601 ctgccaccac gccgattacg ccgacctcct catctgcggc ggcacacact tgggctacct
     3661 gcaccatatg gcgcaaaaac cgaacctgct cgaccgcctc gccatacgcc gtaaccgcag
     3721 caactacgcc accgccaaac tgattatggc gcattcccat atgatgcggc gcgaactggt
     3781 cggactgtac ggcgttcccc ctgaaagaat ccaagtcgcc cccccccgca gatacggaac
     3841 gcttcttccc gcaacccgga gaaactgccg acctgcgcgc caaatacggc tttgccgact
     3901 atgaaaccgt tttcctgttc ccatcgaccg gccacacgcg caaaggtctg gaactgcttg
     3961 ccgacttttt cgaacatacc ggcctgcccg tcaagctcgc cgttgtcggc tccccgctcc
     4021 cccgccctat gaaaaacgtc gtcgggctgg gcttctgcac cgatatgccc gaactctacc
     4081 gcgccgccga ctttaccatt atggcctccc tgtacgaacc cttcgggctg gtcggtgtcg
     4141 aatccgtcct atgcggcaca cgcgtcgtcc tctccgaaaa catggcatgt acagaggtca
     4201 tgaacgaaga agccggattc tttttctcac gccaaaaccc ggaaaccctg gcgcaagccg
     4261 ttgcccaagc cgtcagcctt aaaaaacagg gcggacaccg cctgtccgac ccgatgcgtg
     4321 cactgaacta caacccgtcc ctgtcgcacc acatcgaccg actgaccgac atactggcat
     4381 ccgtataaca aaatgccgtc tgaacgagtt ttcagacggc atttttgcaa ccgttgcagc
     4441 cgtgcggcaa aaagctaact ggcaattttc aaaacgtcgt acagatagtt ccgatagtct
     4501 ccgaccagtt tccggttcgg gcagtcttcc aaccctccgc cgcacaaacc gcgcatcgcc
     4561 atattcgcac gcatgaagcc gtctttggct tccagaccag ccgcctccat cagcacgccg
     4621 cctgcaaagg caaggtcgag gaaatcctgc cgctgtacga atccgccggc aatattgctc
     4681 ctgacggcaa actgcgttac ataatccggc tgcgcgtaat cccatttctt cctgacggac
     4741 acgccctcaa acggtacctg atgatcgccg aaataaccga aaacaaaggg tttgccgcat
     4801 tcgtgcagat aacggtcgaa actttccacc gctttgtcca aatcggcaat gcgcccgatg
     4861 tagtcgttaa gcgcggatac ggttttcgca ttcaaatcag gtgcatccaa atcaaacaca
     4921 ttgtcggtat ccgtccgata cggcccgtgc tccttcatgg tcagcacata tacgaacatc
     4981 ggctgccgca cgttttccaa atcgggatgg cgtttttcca aaatcatccg cgcatactgc
     5041 atcatttcct cactggaaat atgccacagg tttttgccca tcggcgcggg atagcccaaa
     5101 tcttgcggct ggaacatcag attaaagccg aaatggtcat atgctgcctt ggcattgtag
     5161 ttgcccttgg taaacggcga gagcgccacg caaaaataac cgtgttcgcg caggttgcgg
     5221 acaaaaccgg tctgcaaatg cggcacgacc gagtaaaaca cgccgcttgc caacgcgccg
     5281 aaatccgtgg acggaacacc cgccaaaaac gcaaattctg acttccacgt tgcgccgccg
     5341 aaagtatgca cgcgcaaagg tgaggaaaat acggtatctt cctgccgtcc gaacattttc
     5401 aaatcgggaa tcttggcggc ggcaaagtcg aaacagtgcg gatcgagcgt cgattccatc
     5461 agggtaacga caatatcggg tttctcatcc gacatgccgt acggctgggt ttcagacggc
     5521 atctgtttgg caaacgcttc cccgtcgccc tcgaacacgg gtacttggaa aaacaccgcc
     5581 cgacaggaca tcggcaggtt caaaaatacg tcgcgcccgt cgtccggcag cgagtccagc
     5641 cacgtcttta ccgcgcccgg atgtttggaa aaatgccgca tcgacacgaa cgccgccgca
     5701 aacaaaaccg tgcctgccca acgccatggc aaacccaaag catccgcacc gctccagccg
     5761 aaaaccgcat atgccgccaa agccagcagc cccgccatac cgataaccgc ttccttataa
     5821 tggaacagcg tttcccaatt ccgccagtcg gcaatcagca aaaagtcgga aatcaacaac
     5881 ggctgtttgt aataatggat tttcagcctg tggaacagta tcagcaccac aaaccagacc
     5941 gaagcgaaat tcaaggcgcg ctgccactga gccgtcaaca tcagcatacc gcccgccaaa
     6001 aagacaaaca gcgcggatgc gaaaaaatac gtccaacggt agtgcgacct gataatcagc
     6061 accaacgccg ccgttacaaa caaaaatagg aaaacatagg caaccatccc gccccactcc
     6121 tcaaaacggc atacctgagc cgttgcgaat tattatcgaa agcgtgcatt ataatgcagc
     6181 acaggcgcat cactgccgat atttcagtat aattattcga gatggaatca ctgaaaatgg
     6241 tgaagttaca atgagccctt ttagaggaac taaaaagtga attataaaat atacgatggt
     6301 gcaaagatta ttaaaaaaga aaatttatca attggggatt attctcaaat tgatgatttt
     6361 gtatttttta attgtggaga gaaaagtatt ttaggaagtt ttgttcatat atcatcattt
     6421 accagtatta ttggtggtgg agaattttat atggatcatt tttcaggatt aagcgcaggg
     6481 tgtagaatta ttaccggtag cgatgatttt atgggggggg ttaaccaatc caacagtccc
     6541 atctaaatat actaatgtta aaaaatctag tgttagaatt ggaaaacatg caattttagg
     6601 aacaaatgta acagtattac caggcgttac tattggtgat ggggttgctg ttggagcagg
     6661 ggctatagtg agaaaaaatc ttgagccgtg gactatttat gtcggggtag attgtaaacc
     6721 actgaagcgc agatcacaag ataaaatatt ggagttagag aaacatcttg tagcagaatt
     6781 taatctagat ttatgtccta taatcccatc cccgacacgc cccaacccaa aggaaacgcg
     6841 atgaaactca ttattctcga ccgcgacggc gtcatcaacc gggaccgcga cgacttcgtc
     6901 aaatccgccg acgagtggat acctgtcgaa ggcagtatgg atgcggtggc attcctgacg
     6961 caggcgggct gcaccgttgc cgtcgccacc aaccaatccg gtatcgggcg caaatatttt
     7021 accgttcaag accttaccga aatgcacgcc aaaatgcacc gcctcatccg tcaggcaggc
     7081 ggggaaatcg acggcatctg gttctgcccg cataccggcg ccgacggctg cggctgccgc
     7141 aagcccaaac cgggcatgat tgaagacatc ctcgaacgct tcaacgccca agcttcggaa
     7201 acttggctgg tcggcgacag cctgcgcgat ttgcaggcaa tcgatgccgt cggcggaaaa
     7261 cccgcgctgg ttctgaccgg aaaaggcaaa aaaacgctct cccaacacgg acacgaattg
     7321 cccgaacaca cacaggtttt cgataccctg ctcgatttct cacaatacat catgcaggaa
     7381 aacgccgcac cgcaagccga ctgaacatac cgcatttccg acaaggcaaa accatgctca
     7441 tcatccgcaa cctgatttac tggctgatac tctgttccag cctgattttc ctctttccct
     7501 ttatgctgct cgcctcgcct ttccaggacg gggcgcacaa gatggcgcgg atctgggtcg
     7561 gcatcctcaa ctggtcgctc aaacacatcg tcgggctcaa ataccgcatc atcggcgcgg
     7621 aacacattcc ggaccgcccc gccgtcatct gcgccaaaca ccaaagcggc tgggaaacgc
     7681 ttgcccttca agacattttt ccgccgcagg tttacgttgc caaacgcgag ctgtttaaaa
     7741 tccccttttt cggctggggt ttaaaactgg tcaaaaccat aggcatagac cgcagcaacc
     7801 gccgcgaagc caacgaacag ctcataaagc agggtttggc gcgcaaaaac gaaggctatt
     7861 ggattaccat tttccccgaa ggcacgcgcc ttgcacccgg aaagcgcggc aaatacaaac
     7921 tcggcggcgc gcgcatggcg aaaatgtttg agatggacat cgtccccgtc gccctcaaca
     7981 gcggcgaatt ttggccgaaa aactcctttc tgaaatatcc gggggaaatc accgtcgtca
     8041 tctgtccgac catcccgtac gcaagcggca gcgaagccga attgatggaa aaatgcgaac
     8101 acctcatcga aacgcagcag ccgctcattt ctggcgcagg cccgtttgcc gccaaaatgc
     8161 cgtctgaaac cgcatgaccg cctttgtcca caccctttca gacggcatgg aactgaccgt
     8221 cgaaatcaag cgccgtgcca agaaaaacct gattatccgc cccgccggca cacataccgt
     8281 ccgcatcagc gtcccaccct gcttctccgt ctccgctcta aaccgctggc tgtatgaaaa
     8341 cgaagccgtc ctgcggcaaa cactggcgaa aacaccgccg ccgcaaactg ccgaaaaccg
     8401 gctgcccgaa tccatcctct tccacggcag acagcttgcc cctaccgccc atcaagacac
     8461 gcaaatcctg ctgatgccgt ctgaaatccg tgttcccgaa ggcgcacccg aaaaacagct
     8521 tgcgctgctg cgggactttt tggaacggca ggcgcacagt tacctgattc cccgcctcga
     8581 acgccacgcc cgcaccacac aactgttccc cgcctcctcc tcgctgacct ctgccaaaac
     8641 cttctggggc gtgtgccgca aaaccacaga catacgcctc aactggcggc tggtcggcgc
     8701 accggaatac gttgccgatt atgtctgcat acacgaactc tgccacctcg cccatcccga
     8761 ccacagcccc gccttttggg aactgacccg ccgcttcgca ccctacacgc ccgaagcgaa
     8821 acagtggctc aaaatccacg gcagggaact tttcgccttg ggctgacacg gtcccgggcc
     8881 ggcccgccgc tttcagacgg catccgtgcc ggaacaggca cacgcccgcc cgattcaaac
     8941 cgcgatgacg ctttgccgcc ggttcggagc aggatggcgg cacacgcgcc gtctgccgcg
     9001 tttcatttca caccgctctt ccgaaacccg aaacccgccc ggtccgacgt gcggtatgaa
     9061 acgcttaagc tggcgcgaag tcttttactg atttgcccgc gaaaatgccg tctgaaaggt
     9121 tttcggacgg catttttttg cgtttcccag gatggcggcg gattcgtaaa aggcggtcag
     9181 ggtggattgt aggatgggtt gagacctgcc gaatccgccg catctgccaa atctaccgcc
     9241 gtcattccta cgaaagtggg aatctagaac gcggggttaa gaaaacctgc accgcgtcat
     9301 tcccacgaaa gtgagaatcc aggacgcaaa atctccagaa accgttttat ccgataagtt
     9361 tccgcaccga caaaactaga ttcccgcctg cacgggaatg acgaatccat ccatacggaa
     9421 acctgcatc
//
LOCUS       DAXIDM010000071         9428 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000071 DAXIDM010000000
VERSION     DAXIDM010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9428
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.071"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..327
                     /locus_tag="ACFOAE_001466"
     CDS             <1..327
                     /locus_tag="ACFOAE_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-fructose-6-phosphate
                     aminotransferase"
                     /protein_id="HFC6884932.1"
                     /translation="TEEGIAQTVVKGKTTRAEVEARFGKRNPFGCYAYHEVSLPIYNF
                     LPTNFIYMKSERRHWEWCVDYDGEGVVRDYRFTHKVEKDERSVNRDTVDVIRKEAGKS
                     LAKPEK"
     gene            390..1673
                     /gene="hemL"
                     /locus_tag="ACFOAE_001467"
     CDS             390..1673
                     /gene="hemL"
                     /locus_tag="ACFOAE_001467"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA];
                     GO_process: GO:0033014 - tetrapyrrole biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HFC6884933.1"
                     /translation="MNRNEILFDRAKAIIPGGVNSPVRAFGSVGGVPRFIKKAEGAYV
                     WDENGTRYTDYVGSWGPAIVGHAHPEVVETVREAALGGLSFGAPTEGEIVIAEEIAKI
                     MPSVERLRLVSSGTEATMTAIRLARGFTGRDKIIKFEGCYHGHSDSLLVKAGSGLLTF
                     GNPSSAGVPADFTKHTLVLEYNNIAQLEEAFAQSGNDIACVILEPFVGNMNLVRPTEA
                     FVKALRELTEKHGAVLIYDEVMTGFRVALGGAQSLHGITPDLTTMGKVIGGGMPLAAF
                     GGRKDIMECISPLGGVYQAGTLSGNPIAVAAGLKTLEIIQREGFYENLTARTEQLVQG
                     FQTAADAAGIEFTADSVGGMFGLYFAAHAPRNYADMARSNIEGFKQFFHGMLDRGIAF
                     GPSAYEAGFVSAAHTPELIDETVAVAVEVFKAMAA"
     gene            complement(1889..2161)
                     /locus_tag="ACFOAE_001468"
     CDS             complement(1889..2161)
                     /locus_tag="ACFOAE_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taxon MazF"
                     /protein_id="HFC6884934.1"
                     /translation="MPSETQILHFRRHFYSRLKSKIYTPVIPAQAGIRKVGLVGHEVV
                     LKMKRYRKSDELKEKYSDIDETFEFIKGFIYVIALAFTAYVAIRFF"
     gene            complement(2172..2735)
                     /gene="orn"
                     /locus_tag="ACFOAE_001469"
     CDS             complement(2172..2735)
                     /gene="orn"
                     /locus_tag="ACFOAE_001469"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000175 - 3'-5'-RNA exonuclease activity
                     [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HFC6884935.1"
                     /translation="MQDKNNLCWLDMEMTGLNPETDRIIEVAMIITDSDLNVLAQSEV
                     YAVHQSDELLDNMDEWNTATHGRTGLTQRVRESSHTEAEVEQKLLDFMSEWVPGRATP
                     MCGNSIHQDRRFMVKYMPKLENYFHYRNLDVSTLKELAKRWNPPVAKSVVKRGSHKAL
                     DDILESIEEMRHYREHFLISAPRAEAQ"
     gene            complement(2753..3640)
                     /gene="prmA"
                     /locus_tag="ACFOAE_001470"
     CDS             complement(2753..3640)
                     /gene="prmA"
                     /locus_tag="ACFOAE_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFC6884936.1"
                     /translation="MPYQQITVNVNDAVAERLADALMEHGALSAAIEDAYAGTQNEQA
                     IFGEPGMPAEQIWQQSKVIALFGEHDEAAAIIQIAAQECGLKDLAYTGETIEDQDWVR
                     LTQSQFDPIRISDRLWITPSWHEVPEGSAVNLRLDPGLAFGTGSHPTTRLCLKWLDTQ
                     LKNGESVLDYGCGSGILTIAALKLGAGSAVGVDIDEQAVRAGRDNAEQNNVDAQFFLP
                     DGLPQGQFDVVVANILANPLRMLGEMLAARTKQGGRIVLSGLLDEQAEELGGIYSQWF
                     DLDPAETEEGWARLSGTKR"
     gene            complement(3758..5119)
                     /gene="accC"
                     /locus_tag="ACFOAE_001471"
     CDS             complement(3758..5119)
                     /gene="accC"
                     /locus_tag="ACFOAE_001471"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFC6884937.1"
                     /translation="MLKKVLIANRGEIALRVLRACREMGIATVAVHSEADKDSLHVKL
                     ADESVCIGPAASAQSYLNVPAIIAAAEVSCADAVHPGYGFLAENADFAEQVEQSGFTF
                     IGPKPDTIRLMGDKVSAKHAMIAAGVPCVPGSDGALPDDGEEILKIADKVGYPVIIKA
                     SGGGGGRGMRVVEKKEDLLQSVEMTKAEAGAAFGNPMVYMERYLQRPRHVEIQVIADE
                     HGNAIYLAERDCSLQRRHQKVIEEAPAPFITEKERAKIGNACADACKRIGYRGAGTFE
                     FLYEDGEFFFIEMNTRVQVEHPVTELITGVDIVQEQLRIAAGLPLQYKQKDIQVEGHA
                     FECRINAEDPYNFIPSPGPIESCHLPGGFGIRVDSHIYQGYRIPPYYDSLIGKICVHG
                     KTREQAMAKMRVALAELAVTGIKTNTPLHRDLFADAGFQKGGVSIHYLEHWLEDRKAK
                     QDK"
     gene            complement(5232..5687)
                     /gene="accB"
                     /locus_tag="ACFOAE_001472"
     CDS             complement(5232..5687)
                     /gene="accB"
                     /locus_tag="ACFOAE_001472"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFC6884938.1"
                     /translation="MDLRKLKKLIDLVEESGIAEIEVTEGEEKVRITRTIAAAPVYAA
                     PVPAAAPAVTPAAAPVAASAPAAAPAARDLSDAQKSPMVGTFYRAPGPNAAPFVEVGQ
                     QVKAGDTLCIIEAMKLMNEIEAEKSGTVKEILVENGTPVEFGEPLFIIG"
     gene            complement(5669..5926)
                     /locus_tag="ACFOAE_001473"
     CDS             complement(5669..5926)
                     /locus_tag="ACFOAE_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase"
                     /protein_id="HFC6884939.1"
                     /translation="MRKIKLPAHFPQKPPFFDILLDIYRQLRENKHILTVVFHHRKTV
                     SEHHSARFAPLPQAGCFLKNQRNNPPEHRQPLKEQKWICAN"
     gene            6043..7083
                     /gene="queA"
                     /locus_tag="ACFOAE_001474"
     CDS             6043..7083
                     /gene="queA"
                     /locus_tag="ACFOAE_001474"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFC6884940.1"
                     /translation="MDISDFDFTLPEKLIAQHPPEVRGSSRLLVALPDMPLQDRVFGD
                     LQDYVEAGDVLVFNNTKVMKARLFGQKDSGGRIEALIERVLDNHTALAHIRSSKSPKP
                     GMGLVFEGGIRAVTVGREGELFCLRFEGGQTVYELLEQNGHLPLPPYIERAADADDDS
                     RYQTVYAKYQGAVAAPTAGLHFTEELLRRLKDKGAVTAEVTLHVGAGTFQPVRVEKIE
                     EHKMHSEWFEVPSETAAAVEAAKARGNKVWAVGTTSMRALESAARATGRLKAGQGDTD
                     IFITPGYRFNVADRLVTNFHLPKSTLLMLVSAFSGMGHIRAAYRYAVEREYRFFSYGD
                     AMVLGRNEGVVR"
     gene            complement(7557..8135)
                     /locus_tag="ACFOAE_001475"
     CDS             complement(7557..8135)
                     /locus_tag="ACFOAE_001475"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005694496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFC6884941.1"
                     /translation="MNILLLDGGKAFGHSHGGLNRTLHKKAKEVLTALGHNVQETVID
                     AGYDVEAEIEKFVWMDAVIWQMPSWWMHEPWTVKKYIDEVLTAGHGKLYQSDGRHRVN
                     PTEGYGTGGLLQGKKHMLSLTWNAPIEAFTREGDFFEGKGVDVLYMHFHKANEFLGMT
                     RLPTFLCNDVVKNPQVEKYLADYQAHLEKVFG"
     gene            8374..9273
                     /gene="crgA"
                     /locus_tag="ACFOAE_001476"
     CDS             8374..9273
                     /gene="crgA"
                     /locus_tag="ACFOAE_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151940473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator CrgA"
                     /protein_id="HFC6884942.1"
                     /translation="MKTNSEELTVFVQVVESGSFSRAAEQLAMANSAVSRIVKRLEEK
                     LGVNLLNRTTRQLSLTEEGAQYFRRAQRILQEMAAAETEMLAVHEIPQGVLRVDSAMP
                     MVLHLLAPLATKFNERYPHIRLSLVSSEGYINLIERKVDIALRAGELDDSGLRARHLF
                     DSRFRVIASPEYLAKHGTPQSTEELAGHQCLGFTEPSSLNTWAVLDAQGNPYKISPHF
                     TASSGEILRSLCLSGCGIACLSDFLVDNDIAEGKLIPLLAEQTSDKTHPFNAVYYSDK
                     AVNLRLRVFLDFLVEELGNNLCG"
BASE COUNT         2085 a         2344 c         2675 g         2324 t
ORIGIN      
        1 acggaagagg gaatcgcaca aacggttgtt aaaggcaaaa cgactcgggc ggaggtagag
       61 gcacgtttcg ggaagcgcaa ccctttcggt tgttatgcct atcatgaagt cagcctgccg
      121 atttataatt ttttgccgac caatttcatt tatatgaaat cagaacgccg gcattgggag
      181 tggtgtgtgg attacgacgg ggagggagtt gtccgggact accgctttac acataaagtg
      241 gaaaaagacg aacgttccgt caaccgggat acggttgacg tcatccgcaa agaagcaggc
      301 aaatccttgg cgaaacctga aaaatgataa aatagctttt ctatttcaga acctaaaacc
      361 tgcttttagg atggaattta aggatatata tgaaccgtaa cgaaatttta ttcgaccgcg
      421 ccaaagccat catccccggc ggcgtgaatt cccccgtccg cgcattcggc agcgtcggcg
      481 gcgtaccgcg ctttatcaaa aaagccgaag gcgcgtatgt ttgggacgaa aacggcacgc
      541 gctataccga ttacgtcggc tcgtggggac ctgcgattgt cggacacgcg caccccgaag
      601 tcgtcgaaac cgtacgcgaa gccgcattgg gcggtttgtc gttcggcgcg cctaccgaag
      661 gcgaaatcgt cattgccgaa gaaatcgcca aaatcatgcc gtccgtcgaa cggctgcgcc
      721 tcgtcagctc cggtaccgaa gcgaccatga ccgccatccg tctggcacgc ggttttaccg
      781 ggcgtgacaa aatcatcaag tttgaaggct gctaccacgg gcattccgac agcctgctgg
      841 tgaaagccgg cagcggcctg ctgacgtttg gcaacccgtc ttccgccggc gtgcctgccg
      901 actttaccaa acatactttg gtactcgaat acaacaatat cgcccaactc gaagaagcct
      961 ttgctcaaag cggcaatgac attgcctgtg tgattttgga gcctttcgtc ggaaatatga
     1021 acctcgtccg tccgaccgaa gcctttgtca aagccttgcg cgaattgacc gaaaaacacg
     1081 gcgcggtatt gatttacgac gaagtgatga ccggtttccg cgtcgcgctc ggcggcgcgc
     1141 aatctttgca cggcatcacg cccgacctga ccacgatggg caaagtcatc ggcggcggta
     1201 tgccgcttgc cgcgttcggc ggccgtaaag acattatgga atgtatttcc ccgttaggcg
     1261 gcgtgtatca ggcaggcacc ttgtcgggca acccgattgc ggttgcggcc ggtttgaaaa
     1321 cgctggaaat cattcagcgc gaaggcttct atgaaaacct gacggcgcgt accgaacagt
     1381 tggttcaagg ttttcagacg gcagcggatg cggcgggcat cgagttcacc gccgacagcg
     1441 tgggcggtat gttcggtctg tatttcgccg cacacgcgcc gcgaaactat gccgatatgg
     1501 cgcgttccaa tattgaaggc ttcaaacagt ttttccacgg gatgctcgac cgcggcattg
     1561 ccttcggccc gtccgcttat gaagcaggtt tcgtttccgc cgcgcatacg cccgagctga
     1621 ttgacgaaac ggttgcggtt gcggttgaag tgttcaaggc gatggctgca tgatgttttg
     1681 acggacagag tttctctgtt cgatttgttt ggcagattga agtaagaatg cacaccgccg
     1741 tcattcccgc gcaggcggga atccagacct ttcagtttct gtaatgattg aaaataacgg
     1801 gccgaaatca gccgcgcccg gcaggaagcc gccgccacct gaaacaatgc cgtctgaagc
     1861 cttcagacgg cattttatcg gaagcgcatc agaaaaaacg gatagcgaca tatgcggtaa
     1921 aagcaagggc aattacatag ataaacccct ttataaattc aaaagtctca tctatatcgc
     1981 tatatttttc tttcagttcg tcagattttc gataacgttt cattttcaag accacttcat
     2041 gaccaacaag cccgaccttc cggattcccg cctgcgcggg aatgacgggc gtgtatattt
     2101 ttgatttcaa tctgctgtaa aaatgccgtc tgaaatgcag gatttgcgtt tcagacggca
     2161 ttgtttgttt cttattgcgc ttcggctctc ggggcggaaa tcagaaagtg ttcgcggtag
     2221 tggcgcattt cttcgatgct ctccaaaatg tcgtccaatg ccttgtgcga accgcgtttg
     2281 acgacgcttt tggcaacggg cggattccag cgtttggcaa gctctttcag tgtggaaacg
     2341 tcaaggttgc ggtagtggaa gtagttttcc agtttcggca tatatttgac cataaaacgc
     2401 cggtcttggt ggatggaatt gccgcacatc ggcgtggcgc gtccgggtac ccattccgac
     2461 ataaagtcca gcagtttctg ttcgacttcg gcttcggtat gcgacgattc gcgtacgcgc
     2521 tgtgtcagcc ccgtcctgcc gtgtgtggcg gtgttccact cgtccatatt gtcgagcagc
     2581 tcgtcacttt ggtggacggc gtaaacttcg gattgcgcca atacattcaa atccgagtcg
     2641 gtaataatca tcgcgacttc gataatgcgg tcggtttcgg gattaagccc cgtcatttcc
     2701 atatcgagcc agcagaggtt gtttttgtcc tgcacggtgt ttcctttccg tttcagcgtt
     2761 ttgtcccgct caagcgcgcc cagccttctt cggtttccgc cgggtcgaga tcgaaccatt
     2821 ggctgtaaat gccgccgagt tcttcggcct gttcgtccaa caaaccggac aacacgatgc
     2881 ggccgccttg tttggtgcgg gcggcgagca tttcgccgag catacgcaaa gggttggcga
     2941 ggatgttggc gacaactacg tcgaattgcc cttgaggcag accgtcgggc aggaagaatt
     3001 gtgcatcgac gttgttctgt tcggcgttgt ccctgccggc gcggacggct tgttcgtcaa
     3061 tatcgacgcc gacggcagaa cctgcgccga gtttgagggc ggcgatggtc aggatgcccg
     3121 aaccgcagcc gtagtcgagg acgctttcgc cgtttttgag ttgcgtatcc aaccatttga
     3181 ggcagaggcg cgtggtcggg tggctgccgg tgccgaaggc gagtccgggg tcgaggcgga
     3241 ggttgacggc gctgccttcg gggacttcgt gccaagaggg ggtaatccac aggcggtcgg
     3301 aaatccggat ggggtcgaat tgcgattgcg tgagacgcac ccagtcttgg tcttcgatgg
     3361 tttcgccggt gtatgccaag tcttttaacc cgcattcttg tgcggcgatt tggatgatgg
     3421 cggcggcttc gtcgtgttcg ccgaacaggg cgatgacttt gctctgctgc cagatttgtt
     3481 cggcgggcat accgggttcg ccgaaaatcg cctgttcgtt ttgcgtaccg gcgtaggcat
     3541 cttcgatggc ggcggagagt gcgccgtgtt ccatcagcgc gtcggcgagg cgttcggcga
     3601 cggcatcgtt gacgttgacg gtgatttgtt ggtagggcat agcgggcttt cttaacagac
     3661 cttcggaata gggtcgtact gtataagggg atgggtgtgt aacggaaatg ccgtctgaaa
     3721 acggacaaac tgtttcagac ggcatatcgg ggacggctta tttgtcctgt ttggctttgc
     3781 gatcttccag ccagtgttcc aaatagtgga tgctgacgcc gcctttttgg aaacccgcat
     3841 cggcgaacag gtcgcggtga agcggcgtat tggttttgat gccggttacc gccagctcgg
     3901 cgagtgcgac gcgcattttc gccattgcct gttcacgcgt tttgccgtgt acgcagattt
     3961 tgccgatcag gctgtcgtag tacggtggga tgcggtagcc ttggtaaatg tggctgtcca
     4021 cgcggatgcc gaagccgccg ggcaggtggc agctttcaat cgggcccggg ctggggatga
     4081 agttgtatgg gtcttcggcg ttgatacggc actcaaacgc gtggccttcg acttgaatat
     4141 ccttttgttt gtattgcaaa ggcaggccgg cggcgatgcg gagttgctcc tgcacaatgt
     4201 ccacgccggt aatcagctcg gtaaccggat gctcaacctg aacgcgcgta ttcatctcga
     4261 taaagaaaaa ttcgccgtct tcgtacagga attcaaacgt acctgcgccg cgatagccga
     4321 tgcgtttgca ggcgtcggca caggcgttgc cgattttggc gcgttctttt tcagtgatga
     4381 acggagccgg tgcttcctcg atgacttttt ggtggcggcg ttgcagcgaa cagtcgcgct
     4441 cggcaaggta gatggcgttg ccgtgttcgt cggcaatcac ttggatttcg acgtggcgcg
     4501 gacgttgcag gtagcgctcc atgtaaacca tcgggttgcc gaatgccgcg cctgcttctg
     4561 ccttggtcat ttcgacagat tggaggaggt cttctttttt ctcgaccacg cgcataccgc
     4621 gaccgccgcc gccgccagag gctttgataa tgacgggata accgacttta tcggcgattt
     4681 tgaggatttc ttcgccgtcg tcgggcaatg cgccgtcaga accggggacg cagggtacgc
     4741 ctgccgctat catcgcgtgt ttggcggaga ctttgtcgcc catcaggcgg atggtgtcgg
     4801 gtttcgggcc gataaaggta aagccggact gctcgacctg ttcggcgaaa tcggcgtttt
     4861 cggcaaggaa accgtagccc ggatggacag cgtccgcgca gcttacttcg gcggcggcga
     4921 taatggcggg gacgttaagg tagctttgcg cggaagcggc agggccgatg cacacggatt
     4981 cgtcggcgag tttgacgtgc aggctgtctt tgtcggcctc ggaatgcacg gcgacggtgg
     5041 caatgcccat ttcgcggcag gcacggagta cgcgtaatgc gatttcgcct cggttggcga
     5101 ttaaaacttt tttcagcatg atgactgttc ctgtggttcc ggcaacccgt ccgtaaaaaa
     5161 aaggtgcggg aacgccgaag ggggaaagca tttcagacgg catcggaagt ttatgccgtc
     5221 tgaaaacagg attatccgat gatgaagagc ggttcgccga attcgacggg cgtaccgttt
     5281 tcgaccagaa tttctttgac cgtgccggat ttttcggctt cgatttcgtt catcagcttc
     5341 atcgcttcga tgatgcacag cgtgtcgccg gctttaacct gttggccgac ttcgacaaaa
     5401 ggcgcggcat tcgggccggg tgcgcggtag aacgtgccga ccataggcga tttttgcgcg
     5461 tcggacaaat cgcgggcggc aggtgcggcg gcgggcgcgg atgccgcaac gggtgcggcg
     5521 gcaggcgtta cggccggcgc ggcggcaggt acgggcgcgg cgtaaacggg tgcggcggcg
     5581 atggttcggg tgatgcggac tttttcctcg ccttcggtta cttcgatttc ggcgataccc
     5641 gattcttcaa ccaaatcaat cagttttttt aatttgcgca aatccatttc tgttccttta
     5701 aaggctgccg gtgttccggc gggttgttgc gttggttttt cagaaaacag ccggcttgcg
     5761 gcaacggtgc aaaccgggcg gaatggtgtt cggatacggt tttcctgtgg tggaaaacaa
     5821 ccgtgagaat gtgtttattt tcccgaagtt gtcggtaaat gtccagtaaa atatcaaaaa
     5881 acggcggttt ttgggggaaa tgtgcaggaa gtttgatttt gcgcacaaga tgttccaggt
     5941 taagagtgtt tattctaatc tgttggtttt tcggacaaag atgccgtctg aaaaagggct
     6001 aaagtgcgta taatggcggc ttgcccgaac gagagtgtaa aaatggatat ttcagatttt
     6061 gattttaccc tgcccgaaaa gctgattgcc cagcatccgc ccgaagtgcg cggcagcagc
     6121 cgccttttgg ttgcgttgcc cgatatgccg ctgcaagacc gggtgttcgg cgatttgcag
     6181 gattatgttg aggcgggcga cgttttggtg ttcaacaaca ccaaagtcat gaaggcgcgg
     6241 ctgtttgggc agaaagacag cggcggcagg atcgaagccc tgattgagcg cgtgttggac
     6301 aaccataccg cactggcgca catccgttcg tccaagtccc ccaagcccgg tatggggctg
     6361 gtgtttgaag gcggcatccg cgccgtgacg gtcgggcgtg agggcgaact gttctgcctg
     6421 cgttttgaag gcggtcaaac cgtttacgaa cttttggaac agaacggaca cctgcccctg
     6481 ccgccttata tcgaacgcgc cgccgatgcg gatgacgaca gccgttatca aaccgtttat
     6541 gccaaatatc agggtgcggt cgccgcgccg acggcgggtc tgcattttac ggaagaactt
     6601 ttgcgccgcc tgaaagacaa aggcgcagta accgcagaag taaccctgca cgtcggtgcg
     6661 gggacattcc aacccgtgcg tgtggaaaaa atcgaagaac acaaaatgca cagcgaatgg
     6721 tttgaagtgc cgtctgaaac cgccgccgcc gttgaggcgg caaaagcccg ggggaacaaa
     6781 gtctgggcgg tcggcacgac ttccatgcgc gccctcgaat ctgccgcgcg tgcgacgggt
     6841 cgtctgaaag cggggcaggg cgacaccgat attttcatca cgccgggcta ccgttttaat
     6901 gttgccgaca ggctggttac caatttccat ctgccgaaat cgacgctgct gatgcttgtc
     6961 agcgcgtttt cgggtatggg tcatatccgc gccgcgtatc gttatgcggt cgaacgcgaa
     7021 taccgtttct tcagctacgg cgatgcgatg gttttggggc ggaacgaagg ggtggtacgt
     7081 tagaacagcc tcaagtctat tgggggaaga caagtgccgt ctgaacggat gttcggacgg
     7141 cattcttttg ttgatttgaa tgaaaggaac tgcatgacat atagtggatt aaatttaaat
     7201 caggacaagg caacgaagcc gtagacagta caaatagtac ggcaaggcga ggcaacgctg
     7261 tactggtttt tgttaatcca ctatagattc aggcgcgaga ggcgagaaac tcagtcattg
     7321 ttgatgacgc gcaatacgtt aaaattcatt ccgttttggt cgtataaaca tattacatac
     7381 gccatttttt tgtattcaag gctgcctgaa aacagtgggc aagaatatct aacccaacga
     7441 aaagctgaaa aagcaacaaa aaataatctg caccttagtc ggttggttag tccaacctta
     7501 ggggtgcaga ccattcaatc tttcaggctg cctttgtttg tttataagat aaatttttag
     7561 ccgaacactt tttccaagtg tgcctgataa tctgccaagt atttttccac ttgtggattt
     7621 ttaaccacat cgttacataa gaatgtcggc aggcgggtca tacccaaaaa ctcgttggct
     7681 ttgtggaagt gcatatacaa aacatcaacg cctttgcctt caaagaaatc gccttcgcgg
     7741 gtaaacgcct caatcggcgc attccaagtc agtgaaagca tatgtttttt gccttgcaac
     7801 aagccgcctg tgccgtagcc ctcagtcgga ttgacgcggt gtctgccgtc gctttggtag
     7861 agtttgccgt gtccagcggt taatacttcg tctatgtatt ttttcactgt ccaaggctcg
     7921 tgcatccacc agctcggcat ctgccaaatc acagcatcca tccaaacgaa tttttcgatt
     7981 tctgcctcaa catcatagcc ggcatcaatc acggtttctt gaacattgtg tccgagcgcg
     8041 gtcaaaactt ctttcgcttt tttgtgaagc gtgcggttta acccgccgtg agaatgtccg
     8101 aacgccttgc cgccgtctaa taataaaata ttcatttgtt acctcgtttg tgaattgatg
     8161 aatgtattgt gccgttttac tttataattt aaaagtgaaa aaataagaaa acacttttgc
     8221 gtcaaatgaa ataatcagat gtttcaacac acgggatgac acataaagcg tctccctatg
     8281 tgccgtcctg attcggaagg ggttacaccc ctcccaaata aagtctgatc ctgccgccct
     8341 aaagggcggg gtttcaaccg aaaaggaaac acgatgaaaa ccaattcaga agaactgacc
     8401 gtatttgttc aagtggtgga aagcggcagc ttcagccgtg cggcggagca gttggcgatg
     8461 gcaaattctg ccgtaagccg catcgtcaaa cggctggagg aaaagttggg tgtgaacctg
     8521 ctcaaccgca ccacgcggca actcagtctg acggaagaag gcgcgcaata tttccgccgc
     8581 gcgcagagaa tcctgcaaga aatggcagcg gcggaaaccg aaatgctggc agtgcacgaa
     8641 ataccgcaag gcgtgttgcg cgtggattcc gcgatgccga tggtgctgca tctgctggcg
     8701 ccgctggcaa caaaattcaa cgaacgctat ccgcatatcc gactttcgct cgtttcttcc
     8761 gaaggctata tcaatctgat tgaacgcaaa gtcgatattg ccttacgggc cggagaattg
     8821 gacgattccg ggctgcgtgc acgccatctg tttgacagcc gcttccgcgt aatcgccagt
     8881 cctgaatacc tggcaaaaca cggcacgccg caatctacag aagagcttgc cggccaccaa
     8941 tgtttaggct tcaccgaacc cagttctcta aatacatggg cggttttaga tgcgcaggga
     9001 aatccctata agatttcacc gcactttacc gccagcagcg gtgaaatctt acgctcgttg
     9061 tgcctttcag gttgcggtat tgcttgctta tcagattttt tggttgacaa cgacatcgct
     9121 gaaggaaagt taattcccct gctcgccgaa caaacctccg ataaaacaca cccctttaat
     9181 gctgtttatt acagcgataa agccgtcaat ctccgcttac gcgtattttt ggatttttta
     9241 gtggaggaac tgggaaacaa tctctgtgga taattctata aaaacctgtc ataaaattgt
     9301 ttttactcac ttaataactt tgagaaaaaa taaataagat gatgtatagc cgcggcaatg
     9361 gcagtctata tggggagcgt gatagggctg ttccttatgt acggcttgtg tgtggcaaca
     9421 tcggcttt
//
LOCUS       DAXIDM010000072         9388 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000072 DAXIDM010000000
VERSION     DAXIDM010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9388
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.072"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            117..683
                     /locus_tag="ACFOAE_001477"
     CDS             117..683
                     /locus_tag="ACFOAE_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP family protein"
                     /protein_id="HFC6884943.1"
                     /translation="MGFYALLLIALGMSMDAFAVALAKGAAVRMPPRKIAATALVFGT
                     VEALTPLAGWVGGFYAKPFISEWDHWAAFVLLGGLGLKMLREGLSGGADDVREAKRES
                     WWLTVLTAFGTSIDSMIVGVGLAFMEVNIAFAAAVIGMATTVMVTVGLTAGRALGVLF
                     GKRAEFAGGLVLIAIGTWTLLSHLGLIQ"
     gene            complement(1358..3394)
                     /locus_tag="ACFOAE_001478"
     CDS             complement(1358..3394)
                     /locus_tag="ACFOAE_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family metallopeptidase"
                     /protein_id="HFC6884944.1"
                     /translation="MTDNALLHLGEEPRFDQIKTEDIKPALQTAIAEAREQIAAIKAQ
                     THTGWANTVEPLTGITERVGRIWGVVSHLNSVADTPELRAAYNELMPEITAFFTEIGQ
                     DIALYNRFKTIKNSPEFATLSTAQKTKLNHDLRDFVLSGAELPPEQQAELAQLQTEGA
                     QLSAKFSQNVLDATDAFGIYFDDAAPLAGIPEDALAMFAAAAQSEGKTGYKIGLQIPH
                     YLAVIQYADNRELREQIYRAYVTRASELANDGKFDNTANIDRTLANALQTAKLLGFKN
                     YAELSLATKMADTPEQVLNFLHDLARRAKPYAEKDLAEVKAFARESLNLADLQPWDLG
                     YASEKLREAKYAFSETEVKKYFPVGKVLNGLFAQIKKLYGIGFTEKTVPVWHKDVRYF
                     ELQQNGETIGGVYMDLYAREGKRGGAWMNDYKGRRRFSDGTLQLPTAYLVCNFAPPVG
                     GREARLSHDEILILFHETGHGLHHLLTQVDELGVSGINGVEWDAVELPSQFMENFVWE
                     YDVLAQMSAHEETGVPLPKELFDKMLAAKNFQRGMFLVRQMEFALFDMMIYSEDDEGR
                     LKNWQQVLDSVRKEVAVVRPPEYNRFANSFGHIFAGGYSAGYYSYAWAEVLSADAYAA
                     FEESGDIAATGKRFWQEILAVGGSRSAAESFKAFRGREPSIDALLSHSGFDNAA"
     gene            complement(3482..4354)
                     /locus_tag="ACFOAE_001479"
     CDS             complement(3482..4354)
                     /locus_tag="ACFOAE_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HFC6884945.1"
                     /translation="MEIWNMLDTWLGAVPIRAEAVESVAVVAALLLARALLLNIHFKR
                     HPDFGIESKRRFLVASRNITLLLVLFSLAFIWSAQIQTLALSMFAVAAAVVVATKELI
                     MCLSGSILRSATQQYSVGDYIEINGLRGRVVDINLLNTLMMQVGPNPLVGQLAGTTVS
                     FPNSLLLSHPVRRDNILGDYVIHTVEIPVPIHLDSDEAVCRLKAVLEPLCAPYIPAIQ
                     RHLENVQAEKLFITPAARPRVTRVPYDDKAYRIIVRFASPVSKRLEIQQAVMDEFLRV
                     QYRLLNYPAGSETL"
     gene            4624..7014
                     /gene="gyrB"
                     /locus_tag="ACFOAE_001480"
     CDS             4624..7014
                     /gene="gyrB"
                     /locus_tag="ACFOAE_001480"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004283954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFC6884946.1"
                     /translation="MTEQKHEEYGADSIQVLEGLEAVRKRPGMYIGDTQDGSGLHHMV
                     FEVLDNAIDEALAGHCDKITVTIHADHSVSVADNGRGMPTGIHPKEGRSAAEVIMTVL
                     HAGGKFDNNSYKISGGLHGVGVSVVNALSDWVTLTIYRDGKEHFVRFVRGETEEPLKI
                     VGDSDKKGTTVRFLASTETFGNVEYSFDILAKRIRELSFLNNGVDIELTDERDGKHES
                     FALSGGVAGFVQYMNRKKTPLHEKIFYAFGEKDGMSVECAMQWNDSYQESVQCFTNNI
                     PQRDGGTHLTALRQVMTRTINSYIEANEVAKKAKVETAGDDMREGLTCVLSVKLPDPK
                     FSSQTKDKLVSSEIGPVVNEVINQALTDFLEENPNEAKIITGKIVDAARAREAARKAR
                     EITRRKGVMDGLGLPGKLADCQEKDPALSELYLVEGDSAGGSAMQGRDRKFQAILPLK
                     GKILNVEKARFEKMLASQEVAALITALGAGIGKEEFNAEKLRYHRIIIMTDADVDGAH
                     IRTLLLTFFYRQMPELVERGYIYIAQPPLYKAKYGKQERYLKDELEKDQWLLGLALEK
                     AKIISDGRTIEGAELADTAKQFLLAKTVIEQESRFVDELVLRAMLHASPVDLSTAESA
                     DRSVAELNGLLDEKEVALERIEGHEGHRFIKITRKLHGNVMVSYIEPKFLNSKAYQTL
                     TQTAAALKGMVGEGAKLYKGENGYDADSFETALDILMSVAQKGMSIQRYKGLGEMNPE
                     QLWETTMDPAVRRLLKVRIEDAIAADEVFVTLMGDEVEPRRAFIENNALIAQNIDA"
     gene            7275..8651
                     /locus_tag="ACFOAE_001481"
                     /pseudo
     CDS             7275..8651
                     /locus_tag="ACFOAE_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224807.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
     gene            complement(8722..8820)
                     /locus_tag="ACFOAE_001482"
     CDS             complement(8722..8820)
                     /locus_tag="ACFOAE_001482"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="eamA-like transporter family protein"
                     /protein_id="HFC6884947.1"
                     /translation="MAVVFLDERPNTQEWIGLGLVTAGVLTLALKR"
     gene            complement(9176..>9388)
                     /locus_tag="ACFOAE_001483"
     CDS             complement(9176..>9388)
                     /locus_tag="ACFOAE_001483"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884948.1"
                     /translation="VKEYQPPVGIFLFVCFEKCLFPDFAIPIRFCAVRCVLARTCSKS
                     HVIPVFEALIRDADFQYIFSATTTKA"
BASE COUNT         2166 a         2498 c         2617 g         2107 t
ORIGIN      
        1 gatttctgtt tttgattttt tgtttttgca ggaatgacgg gatgtgggtt ttcgtgcggc
       61 gtttttgcat ttttttgctt ttgctataat ccgccctttt tgaggacggg tgcggtatgg
      121 gtttttatgc tttgctcttg attgcgctgg ggatgtcgat ggatgcgttt gccgtcgcat
      181 tggcaaaggg tgcggcggtc agaatgcctc cgcgcaaaat tgcggcaacg gctttggtgt
      241 tcggcacggt tgaagcgctc acgccgctgg caggctgggt gggcggtttt tatgccaagc
      301 cgtttatcag cgaatgggac cattgggcgg ctttcgtcct gctgggcggg ctgggtctga
      361 agatgttgcg tgagggcttg tccggcgggg cggacgatgt gcgcgaagcc aaacgggaaa
      421 gctggtggtt gacggttctg actgcttttg gaaccagtat tgattccatg atagtcgggg
      481 tgggcttggc gtttatggag gtaaacatcg cctttgccgc cgccgtcatc ggcatggcga
      541 cgacggtgat ggttacggtc gggctgacgg cgggaagggc tttgggcgta ttgttcggca
      601 aacgcgccga gtttgccgga ggtttggtgt tgattgccat cggtacatgg acgctcttgt
      661 cgcatttggg tttgattcaa tgatgtcgga aaatatagtg gattaacaaa aaccagtacg
      721 tcgttgcctc gccttggctc aaagagaacg attctctaag gtgctgaagc accaagtgaa
      781 tcggttccgt actatttgta ctgtctgcgg cttcgtcacc ttgccctgat ttttgttaat
      841 ccactataaa atgccgtctg aagcgttgtt tgaccgtttc agacggcatt tttatcaaat
      901 tcaaaaatat tccgtcattc ccgcgaaagc gggaatctag aacgtaaaat ctaaagaaac
      961 cgttttatcc gataagtttc cgcaccgaca gacctggatt cccgcctgcg cgggaatgac
     1021 gggatttctg tttttgattt ttttgttttt ggggaatgac aggatttgag attgcgggca
     1081 tttatcaggt aaaacggaaa ttaaacgttg cgaaaattta tccgaaatca cagcaacttt
     1141 tccgcgtcat tcccgcgaaa gcgggaatct aggattcagg accggagaaa cctttttacc
     1201 cgataagttt ccgtgccgac cggtctggat tcccgcctgc gcgggaatga cgggattttg
     1261 gcttactgtt tttgtgaaaa tggcgaaacc gtgcaaatgc tgatgccgtc tgaaacactg
     1321 tttgattgtt tcagacggca ttttttgttc acatcgatca agccgcgttg tcgaagccgc
     1381 tgtggctcag cagtgcgtct atgctcggtt cgcgtccgcg gaaggctttg aaggattctg
     1441 ccgcgctgcg cgatccgccg acggcgagga tttcttgcca gaagcgtttg cctgtggcgg
     1501 caatgtcgcc gctttcttca aaggcggcgt atgcgtccgc gctcaatact tccgcccatg
     1561 cgtagctgta atagcctgcg gagtagccgc cggcgaagat gtggccgaag ctgttggcga
     1621 agcggttgta ttcgggcggt cggacgacgg cgacttcttt gcgcacgctg tctaaaacct
     1681 gttgccagtt tttcagacgg ccttcgtcgt cttcgctgta aatcatcata tcaaagaggg
     1741 cgaactccat ttgccggacg aggaacatgc cgcgttggaa gtttttggcg gcgagcattt
     1801 tgtcgaagag ttctttcggc aggggaacgc cggtttcttc gtgggcggac atttgtgcca
     1861 agacgtcgta ttcccagacg aaattttcca taaactggct gggcagttcg accgcgtccc
     1921 attctacgcc gttgatgccg gatacgccca gttcgtccac ttgggtaagc aggtggtgca
     1981 gcccgtgtcc ggtttcgtgg aagaggatga ggatttcgtc gtggctcaaa cgcgcttctc
     2041 tgccgccgac gggcggggcg aagttgcaga cgaggtaggc ggtgggcagt tgcagcgtgc
     2101 cgtctgaaaa acggcggcga cctttgtagt cgttcatcca cgcgccgccg cgtttgcctt
     2161 cgcgtgcgta caaatccata taaacgccgc ctatggtttc gccgttttgt tgcaattcaa
     2221 aatagcgcac gtctttgtgc cagacgggga cggttttttc ggtaaatccg atgccgtaga
     2281 gttttttgat ttgggcgaac agtccgttta atactttgcc gacggggaag tattttttga
     2341 cttcggtttc gctgaacgcg tatttggctt cgcgcagttt ttcgctggcg tagcccaagt
     2401 cccacggttg caaatcggcg aggttcaggc tttcgcgggc gaaggctttg acttcggcga
     2461 ggtctttttc ggcgtagggt ttggcgcggc gggcgaggtc gtgcaggaag tttaaaactt
     2521 gttcgggcgt gtccgccatt ttggttgcca gcgacaattc ggcgtagttt ttgaagccga
     2581 gcagtttggc ggtttgcagg gcgtttgcga gcgtgcggtc gatgttggcg gtgttgtcga
     2641 atttgccgtc gtttgcgagt tcgctggcgc gggtaacgta ggcgcggtag atttgttcgc
     2701 gcagttcgcg gttgtcggcg tattggatga cggcgaggta gtgtggaatc tgcaagccga
     2761 ttttgtagcc tgttttgcct tcgctttgcg cggcggcggc aaacatcgcg agcgcgtctt
     2821 cgggaatgcc ggcaagcggt gcggcatcgt caaagtaaat gccgaatgcg tcggtcgcgt
     2881 ctaggacgtt ttgcgagaat ttggcggaga gttgtgcgcc ttcggtttgc agttgggcca
     2941 gttctgcctg ctgttcgggc ggcagttccg cgccgctgag gacgaaatcg cgcaggtcgt
     3001 ggttgagctt ggttttttgt gcggtggaaa gcgttgcaaa ttcgggggag tttttgatgg
     3061 ttttgaagcg gttgtataag gcaatatctt gtccgatttc ggtaaagaag gcggtgattt
     3121 cgggcattaa ttcattgtag gcggcgcgca gttcgggcgt gtcggcgacg gagttgaggt
     3181 gcgacaccac gccccaaatc ctgccgacgc gttcggtgat gccggtcagg ggttcgacag
     3241 tgtttgccca gccggtgtgc gtttgggctt tgatggcggc gatttgttcg cgcgcttcgg
     3301 cgatggcggt ttgcagggcg ggtttgatgt cttcggtttt gatttgatca aaacggggtt
     3361 cttcgcccaa atggagcagt gcgttgtcag tcataagatg ggtttccttt gcgtgttgtg
     3421 cttcagacag catatcggca atatgccgtc tgaagccgga aatggggtcg gtcggggaaa
     3481 gttaaagtgt ttcggagccg gcggggtaat ttaacaggcg gtattgtacg cgcaaaaatt
     3541 cgtccataac cgcctgttgg atttccagcc gctttgaaac gggggaggcg aagcggacga
     3601 tgatgcggta tgccttgtca tcgtacggca cgcgggtaac gcgcggtctg gcggcgggcg
     3661 tgataaacag tttttccgcc tgcacgtttt ccaaatgccg ttggatggcg gggatgtagg
     3721 gcgcgcacaa gggctcgagt acggctttca gacggcatac ggcttcatcc gaatccaaat
     3781 ggatgggaac ggggatttcg accgtatgga tgacatagtc gcccaaaata ttgtcgcggc
     3841 gcacggggtg gctcaacaac aggctgttgg ggaaagaaac ggtggttccc gcaagctgtc
     3901 cgaccaaggg gttcggaccg acctgcatca tcagcgtgtt caacaggttg atgtcgacca
     3961 cgcgcccgcg caggccgttg atttcgatat agtcgccgac cgagtattgc tgggtggcag
     4021 accttaaaat actgcccgac agacacataa tcagttcctt cgtcgccacg acgaccgccg
     4081 ccgccaccgc aaacatcgac aaagccagcg tttggatttg cgccgaccag ataaatgcca
     4141 gcgaaaacag caccaaaagc agcgttatat tgcggctggc aaccaaaaac cgccgcttgc
     4201 tttcgatgcc gaaatccgga tgccgtttga agtggatatt caacagaagg gcgcgcgcca
     4261 gcagcaaagc cgcaaccacc gccacggatt cgaccgcctc cgcacgtatc gggacggcac
     4321 cgagccaagt gtccaacata ttccatattt ccatttccgc gcccctgtcc gaaaagtata
     4381 gggcgtagat tttagtggca aaaaaacgct tttgccactt tacgggaaaa tccccgacct
     4441 gatgccggag gcaaacgtac cgtttcatct tttcccggcg gcacactgat gcggataacg
     4501 ctgaattagg cggcaaaatc ggctataata cacaattata tatgccgtcc cgcccgcttt
     4561 ttctacaagg tgcggacttg ttttggcggc atcgcaaaat cttttcaaaa tccggcaaaa
     4621 aatatgactg aacaaaaaca cgaagaatac ggcgccgaca gcattcaggt gctcgaaggc
     4681 ttggaagcgg tacgcaaacg ccccggcatg tacatcggcg acacgcagga cggcagcggt
     4741 ctgcaccaca tggtgttcga agtattggac aacgccattg acgaagcact cgccggacat
     4801 tgcgacaaaa tcacggtaac gatacacgcc gaccattccg tcagcgtcgc cgacaacggg
     4861 cgcggtatgc ccaccggcat ccacccgaaa gaaggacgct ccgccgccga agtcatcatg
     4921 accgtattgc acgcaggcgg caagttcgac aacaacagct acaaaatctc cggcggcctg
     4981 cacggcgtgg gcgtgtccgt cgtcaacgcg ctgtccgact gggttacgct gaccatctac
     5041 cgcgacggca aagaacactt cgtccgcttc gtgcgcggcg aaaccgaaga gccgctgaaa
     5101 attgtcggcg attccgacaa gaaaggcacg accgtacgct tcctcgccag cacggaaact
     5161 ttcggcaacg tcgaatacag cttcgacatc ctcgccaaac gcattcgcga actttccttc
     5221 ctgaacaacg gcgtggacat cgaattgacc gacgaacgcg acggcaaaca cgaaagcttc
     5281 gccctttccg gcggcgtggc cggtttcgtg caatacatga accgcaaaaa aacgccgttg
     5341 cacgaaaaaa tcttctatgc gttcggcgag aaagacggca tgagcgtcga atgcgcgatg
     5401 cagtggaacg acagctacca agaaagcgtg cagtgcttca ccaacaacat ccctcagcgc
     5461 gacggcggta cgcacttgac cgcgttgcgc caagtgatga cacgcaccat caacagctac
     5521 atcgaagcca acgaagtcgc caaaaaagcc aaagtggaaa cagcaggcga cgatatgcgc
     5581 gaaggtttga cctgcgtgtt gtccgtcaaa ctgcccgacc ccaaattctc atcccaaacc
     5641 aaagacaaac tggtttccag cgaaatcggc cccgttgtca acgaagtcat caaccaagcg
     5701 ctgaccgact tccttgaaga aaacccgaac gaagccaaaa tcatcaccgg caaaatcgtc
     5761 gatgccgccc gcgcgcgcga agccgcccgc aaagcccgcg aaatcacccg ccgcaaaggc
     5821 gtaatggacg gcttggggct acccggtaaa ctcgccgact gccaagaaaa agaccccgca
     5881 ttgtcagaac tttatctggt cgagggcgat tctgcaggcg gttccgccat gcaggggcgc
     5941 gaccgcaaat tccaagcgat tttgccgctt aagggcaaga ttttgaacgt cgaaaaagcg
     6001 cgctttgaaa aaatgctcgc cagtcaggaa gtagccgctt tgattaccgc gttgggcgcg
     6061 ggcatcggca aagaagaatt caatgccgaa aaactgcgtt accaccgcat catcatcatg
     6121 accgatgccg acgtggacgg cgcgcacatc cgcaccctgc tcctgacctt cttctaccgc
     6181 caaatgcccg agctggtcga acgcggctac atctacattg cccagccgcc tttatacaaa
     6241 gccaaatacg gcaaacaaga acgatatctc aaagacgaat tggaaaaaga ccaatggctg
     6301 ctcggtttag ccttggaaaa agccaaaatc atttcagacg gccgcaccat cgaaggcgca
     6361 gaacttgccg acaccgccaa acaattcctg ttggcaaaaa ccgtcatcga acaggaaagc
     6421 cgcttcgtag acgaactcgt cctgcgcgcc atgctacatg cttcgccggt cgatctcagc
     6481 acagcagaaa gcgcagaccg ctccgttgcc gaattgaacg gcctcttgga cgaaaaagaa
     6541 gtcgcgctcg aacgtatcga aggccacgaa ggacaccggt tcatcaaaat cacgcgcaag
     6601 ctgcacggca acgtcatggt cagctacatc gaacccaagt tcctcaacag caaagcctac
     6661 caaaccctca cccaaaccgc cgccgcgctc aaaggcatgg tcggcgaggg tgccaagctt
     6721 tacaaaggcg aaaacgggta cgacgcggac agctttgaaa ccgctttgga catcttaatg
     6781 agcgttgccc aaaaaggtat gtccatccaa cgatacaaag gcttgggcga gatgaacccc
     6841 gaacagctgt gggaaaccac gatggatccc gccgtgcgcc gcctgttgaa agtgcgcatc
     6901 gaagatgcca ttgccgccga cgaagtattc gttaccctga tgggcgacga ggtcgaaccg
     6961 cgccgcgcct ttatcgaaaa caacgcgctg attgcccaaa atatcgacgc ataagtgccg
     7021 ttttaaaaaa ggagacgggc atcgtgccgc gtctcctttt ggtttgtcaa acggaagcca
     7081 tgccgtctga aaccgccttt cggagcaaaa ccatggtcag catttttgat atagtggatt
     7141 aacaaaaatc aggacaaggc gacgaagccg cagacagtac aaatagtacg gaaccgattc
     7201 acttggtgct tcagcacctt agagaatcgt tctctttgag ctaaggcgag gcaacgctgt
     7261 actggttttt gttaatccac tatattttca aaatcggtat cgggccttcc agttcgcata
     7321 cggtcggccc gatgaaggca gccgccgcct ttgcggcagg tttggatgca caggctgttc
     7381 gcatcgtcat cgacatttac ggctcgctcg cactgaccgg atacggacac ggtacatttg
     7441 acgcgctgat gctcggtttg gaaggcagcc tgccgcacga catcccgctt gccggcattc
     7501 ccgaacgcct cgaacgcatc cgcacgcagc acatcctccg gctcaacggg caagaaatcc
     7561 gcttcatccc cgaccgcgac ctgaacatac tcggcaatca agtgctgccc aaacacccca
     7621 acggcctgcg ttttaccgcc tatgcttcag acggcacggt attgaatgaa caggtttatt
     7681 attcggtcgg cggcggcttt gtcgttaccg aagaagattt tgaccggcag gcggaaacgg
     7741 aaaaagccgt tccctatccc tataccagtt gcgccgaact gcttgcccga tgccgtctga
     7801 accggctcga catctccgaa gtcgtgttgg caaacgaagc cgcgcttgcc ggatgcggcg
     7861 aagccgaaat ccgccgccgc gccgctgccg ttgccgaggt tatggaaggc tgcatcaaac
     7921 gcggcttggg tgcggacggc gaactgcccg gctgattgaa cgtccgccgc cgcgccccgc
     7981 atcttgccac caagctcaaa gtcctgcgcg aaaccgaaat cgtcaacacc cagctctggc
     8041 cgatggtgta cgccatggcg gtcaacgaag aaaacgccgc cggcggacgc gtcgttaccg
     8101 ccccgaccaa cggggcggca ggcatcattc ccgccgtatt gcactatttc cgcaagttca
     8161 acccccacgc cacacaggag cgcgtcgaaa acttcctgct caccgccggc gcaatcggca
     8221 tcctctacaa aaccaacgcc tccatttccg gtgcggatgt cggctgtcag ggcgaagtcg
     8281 gcgtagcgtg ttcgatggcg gcgggcgcat acgccgaagt catcggcggc acgcccaaac
     8341 aagtggaaaa cgccgctgaa atggcgatgg aacaccattt ggggctgact tgcgaccccg
     8401 tcggcgggct ggtgcaaatc ccctgtatcg aacgcaacgg catcgccgcc gaaaaagccc
     8461 tcaaactcgg cacgctcgcg cttttggaag acggcacgga caaaaaagtc tcgctcgacg
     8521 aagtcatccg aaccatgctg caaaccggcc gggatatgaa ggcgacctac aaagaaacct
     8581 cgcttgccgg actcgccgcc acgctccgga aaaaagccgt ccccgtatcc gtgcgcgtgg
     8641 tcgagtgctg aggatggaca gaaacgaaaa tgccgtctga aaacagtttt ttagacggca
     8701 tttcatttat ttcttgcggc tttaccgttt cagtgccagc gtcaacacgc ccgccgtaac
     8761 cagccccaag cctatccatt cctgcgtgtt cgggcgttcg tctaagaaaa ccaccgccat
     8821 caggaatgca aaccggcgtt gtttgcagca tccggcaaga atttttatag tggattaaca
     8881 aaaatcagga caaggcgacg aagccgcaga cagtacaaat agtacggaac cgattcactt
     8941 ggtgcttcag caccttagag aatcgttctc tttgagctaa ggcgaggcaa cgctgtactg
     9001 gtttttgtta atccactata aaaggtcttt tctaaaatat gcagatattc gaatatcgaa
     9061 tttgccttat gattacggtt ttctgtctta tctaccttaa aacgccgata ttccgtttga
     9121 accaaattat atttgccgaa acactcaaaa atctccctta cctgcccgac agacatcaag
     9181 ccttcgttgt tgtagctgag aaaatatatt gaaagtccgc atccctaatc aaagcctcaa
     9241 ataccggaat cacatgcgat tttgagcaag tccgcgctaa aacacatcgt acagcgcaaa
     9301 accggatggg aatggcaaaa tccggaaaca aacatttttc aaagcataca aacaaaaaaa
     9361 taccaaccgg aggttggtat tccttaac
//
LOCUS       DAXIDM010000073         9363 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000073 DAXIDM010000000
VERSION     DAXIDM010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9363
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.073"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            90..299
                     /locus_tag="ACFOAE_001484"
     CDS             90..299
                     /locus_tag="ACFOAE_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase family protein"
                     /protein_id="HFC6884949.1"
                     /translation="MPYVNIKVTGGKEAPTAAQKAELIGGVTELLARVLGKNPETTVV
                     VIDEVDTDNWGIGGKSVSERRKEGR"
     gene            388..1602
                     /locus_tag="ACFOAE_001485"
     CDS             388..1602
                     /locus_tag="ACFOAE_001485"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFC6884950.1"
                     /translation="MDKFPKSAKLDHVCYDIRGPVHKKALQLEEEGNKILKLNIGNPA
                     PFGFEAPDEILVDVIRNLPTSQGYCDSKGLYSARKAIVHYYQTKGLRDITVDDVYIGN
                     GVSELITMSMQALLNDGDEILIPAPDYPLWTAAATLAGGTVRHYLCDEENGWFPNLAD
                     MEAKITPKTKAIVVINPNNPTGAVYSREILLEIAELARKHGLIIFADEIYDKILYDGA
                     VHHHIAALAPDLLTVTFNGLSKSYRVAGFRQGWMVLNGPKHHAKGYIEGLDMLSSMRL
                     CANTPMQHAIQTALGGYQSINEFILPGGRLLEQRNRAWELVSQIPGVSCVKPMGAMYM
                     FPKIDTEMYRIRDDMKFVYDLLVREKVLLVQGTGFNWIKPDHFRIVTLPYVHQIEEAM
                     GRLARFLQTYRQ"
     gene            complement(1689..4268)
                     /gene="clpB"
                     /locus_tag="ACFOAE_001486"
     CDS             complement(1689..4268)
                     /gene="clpB"
                     /locus_tag="ACFOAE_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFC6884951.1"
                     /translation="MRYDKLTAKFQQALAEAQSLALAADSSYLEAGFVLKALLDDQNS
                     GAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGDILPSRELQAVLNLMDKAATKRG
                     DAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
                     LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIVNGEVPESLRNKRLLVLDLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIF
                     IDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYRQYIEKDAALERRFQ
                     KVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAID
                     LIDEAASRVKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEING
                     LQKEYADLDEIWKAEKAISDGAANIKKQIDEVKIKIEQAKRQGDLALASKLMYEDLEH
                     LEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGERDKLLKM
                     EEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAG
                     FLFDSEDHLIRIDMSEYMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDE
                     VEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTSNIGSQHIQQMGIQDYEAV
                     KEVVMEDVKEHFRPEMINRIDEVVVFHGLDQDNIRNIAKIQLKGLEKRLEKQNLRLTV
                     SDAALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVETDGDRL
                     KFA"
     gene            4529..5539
                     /gene="trpS"
                     /locus_tag="ACFOAE_001487"
     CDS             4529..5539
                     /gene="trpS"
                     /locus_tag="ACFOAE_001487"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFC6884952.1"
                     /translation="MSKKRVLTGVTTTGIPHLGNYVGAIRPAVRAAQNPDTESFLFLA
                     DYHGIIKCHEPEMIHQSTQAVAATWLACGLDPERTTFYRQSDIPEVMELNWILTCITA
                     KGLMNRAHAYKAAVQANAENGQEDPDFGVEMGLFSYPILMTADILMFNANEVPVGRDQ
                     IQHVEMARDIAGRFNHRFKEIFTLPEVKIDENVELLVGLDGRKMSKSYGNTIPLWEND
                     KKTQKSVNKIITNMKEPGEPKQPDESPLFEIYKAFSTPSETVEFTKMLADGLAWGEAK
                     KLLAAKINAELAEPRERYNELTADPSQIEEILQAGAQKARKEARELLDKVRDVVGIRP
                     LK"
     gene            5545..5886
                     /locus_tag="ACFOAE_001488"
     CDS             5545..5886
                     /locus_tag="ACFOAE_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884953.1"
                     /translation="MPSEPLKGLPEQNVVRLTGKHPNDLEVISGKCMETDGKGAPSGW
                     AANGVCHTLFAKLVGNIAEDGGKLTDYLISHSALQPYQAGKSGYAAVQNGRYVLEIDS
                     EGAFYFRRRHY"
     gene            6205..6549
                     /locus_tag="ACFOAE_001489"
     CDS             6205..6549
                     /locus_tag="ACFOAE_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003674689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884954.1"
                     /translation="MKKLLIAAMMAAALAACSQEAKQEVKEAVQAVESDVKDTAASAA
                     ESAASAVEEAKDQVKDAAADAKASAEEAVTEAKEAVTEAKEAVTEAAKDTLNKAADAT
                     QEAADKMKDAAK"
     gene            complement(6758..8266)
                     /gene="ppx"
                     /locus_tag="ACFOAE_001490"
     CDS             complement(6758..8266)
                     /gene="ppx"
                     /locus_tag="ACFOAE_001490"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004309 - exopolyphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006798 - polyphosphate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HFC6884955.1"
                     /translation="MTTTPANILASVDLGSNSFRLQICENNNGQLKVIDSFKQMVRFA
                     AGLDEQKNLSAASQEQALDCLAKFGERLRGFRPEQVRAVATNTFRVAKNIADFLPKAE
                     AALGFPIEIIAGREEARLIYTGVIHTLPPGGGKMLVIDIGGGSTEFVIGSTLNPDITE
                     SLPLGCVTYSLRFFQNKITAKDFQSAISAARNEIQRISKNMRREGWDFAVGTSGSAKS
                     IRDVLAAEMPQEADITYKGMRALAERIIEAGSVKKAKFENLKPERIEVFAGGLAVMMA
                     AFEEMKLDRMTVTEAALRDGVFYDLIGRGLNEDMRGQTVAEFQHRYHVSLNQAKRTAE
                     TAQTFMDSLCHAKNVTVQELALWQQYLGRAAALHEIGLDIAHTGYHKHSAYILENADM
                     PGFSRKEQTILAQLVIGHRGDMKKMSGIIGTNEMLWYAVLSLRLAALFCRSRQDLSFP
                     KNMQLRTDTESCGFILRIDREWLERHPLIADALEYESVQWQKINMPFKVEAV"
     gene            complement(8383..9114)
                     /locus_tag="ACFOAE_001491"
     CDS             complement(8383..9114)
                     /locus_tag="ACFOAE_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC6884956.1"
                     /translation="MSREINAGGHHFLYGGISGGGVHYWDNKDFSEQCLHLSLGYKNR
                     SVTRSFGIVPFVGQNLLGGSRYNFVGGFNADFSQHLSERWRLTLNAGNMWKHYQEDRT
                     AARYDSHMPLAGATLMYSAPKDWLLYGGADWSHDLTKEAEQASVRKGLRIGAVKTFDG
                     GLGLRANLRYTRRTFDAPGTIVYRFPRKDHEYQANLSFWHDKISWKGFTPQLNFRYLK
                     IDSNMKSFYTRKNTQIFMSVEKDFK"
BASE COUNT         2167 a         2427 c         2468 g         2301 t
ORIGIN      
        1 cgatttgaat ttttcagaaa atgaagcgga cgtttgggcg gaggcaactt gtttgataag
       61 atagcaatat tttaaaacgg agaaagatca tgccttatgt caatattaaa gtaaccggcg
      121 gcaaggaagc accgactgcc gcgcaaaaag cggaactgat cggcggcgta accgaattgc
      181 tggcacgcgt gctgggcaaa aatcccgaaa caacggttgt cgtgattgac gaagtggata
      241 ccgataactg gggaataggc ggcaaaagcg tcagcgaacg gcgcaaagag ggcaggtaaa
      301 aagcctgaaa atctcggttt gatgctttaa attccgcgtg aaaaagagta cattcccacc
      361 cattgcccaa aatttacgga acacatcatg gataaatttc ccaagtctgc aaagctcgat
      421 cacgtctgtt acgacatacg cgggccggtt cacaaaaaag cccttcagtt ggaagaggag
      481 ggcaataaaa tccttaaact caatatcggc aaccctgcgc cgttcggctt tgaagcccct
      541 gatgaaatct tggtcgatgt catccgcaac ctgccgactt cgcaaggcta ttgcgattct
      601 aaagggctgt attccgcccg caaagccatt gttcactact atcagaccaa aggtttgcgc
      661 gatattacgg ttgatgatgt ctatatcggc aacggcgtgt ccgagctgat tacgatgtct
      721 atgcaggcgc tgttgaacga cggcgacgaa atcctgattc ccgcgcccga ctaccctttg
      781 tggacggcgg cggcaacgct tgcgggcggt acggtacgcc attatctgtg cgacgaagaa
      841 aacggctggt tccccaacct tgccgatatg gaagccaaaa tcacgcccaa aaccaaagcc
      901 atcgtcgtca tcaatcccaa taatccgaca ggcgcggtgt acagcaggga aatcctgttg
      961 gaaatcgccg aactggcgcg caagcacggt ttgattattt tcgccgacga gatttacgat
     1021 aaaatccttt atgacggcgc ggttcaccac cacatcgccg cgcttgcccc cgaccttttg
     1081 acggtaacgt tcaacggttt gtccaaatcc taccgcgtcg ccggcttccg ccaaggctgg
     1141 atggtgctca acgggccgaa acatcacgca aaaggttaca tcgagggttt ggatatgctc
     1201 tcgtccatgc gcttgtgtgc caatacgccg atgcagcacg cgattcagac ggcattgggc
     1261 ggctatcaga gcattaacga atttatcctg ccgggcgggc ggcttttgga acagcgcaac
     1321 agggcgtggg aactggtcag ccaaatcccc ggcgtgtcct gcgtcaaacc gatgggcgcg
     1381 atgtatatgt tcccgaaaat cgataccgaa atgtaccgca tccgcgatga catgaaattc
     1441 gtttacgatt tgctggtgcg cgaaaaagtc ttgctggtgc agggaacggg gtttaattgg
     1501 atcaagcccg accatttccg cattgttacg ctgccttacg tccatcagat tgaagaggcg
     1561 atgggcaggc tggcaagatt cctgcaaacc taccgccaat aaggggacgg gctgtctgcc
     1621 gaggataaaa aatgccgtct gaaacggaga ttcccgtttc agacggcatt tttaacagca
     1681 ggaacgaatc aggcaaattt cagtctgtcg ccgtcggttt ccaccctgat ttcgctttcg
     1741 ggcgcatagt ttccggcaag cagggctttt gccagcgggt tttcgatttc cgactggatg
     1801 gcgcgtttga gcggacgtgc gccgtaaatc gggtcgaaac cggctttggc gatgatgtcc
     1861 agagcggcat cggaaacagt caggcggagg ttttgttttt ccaaacgttt ttccaagcct
     1921 ttgagctgga ttttcgcaat gttgcggata ttatcctgat ccagtccgtg gaacacgacc
     1981 acttcgtcga tgcggttgat catttcagga cggaaatgtt ctttcacatc ctccatcaca
     2041 acttctttta ccgcttcgta atcctgaatg cccatttgtt ggatgtgctg gctgccgatg
     2101 ttggaagtca tcacaatcac ggtgttttta aaatctaccg ttctgccctg tccgtcggtc
     2161 aaacggccgt catccaatac ttgcagcagg atgttgaaca cgtccggatg ggctttttcc
     2221 acttcatcca aaagaatcac gctgtatggt ttgcggcgga cttgctcagt caggtagccg
     2281 ccttcttcgt agccgacata gccgggaggc gcaccaatta ggcgggcaac agcatgtttt
     2341 tccatgtatt cggacatatc gatacgaatc agatgatctt cgctgtcgaa caggaagcct
     2401 gccaatgcct tgcacaattc ggtcttaccc acgccggtcg ggcccaagaa caggaagctg
     2461 ccgtagggtt tattcgggtc ggcaagaccg gaacggctgc ggcggatagc gtcggacacg
     2521 gcacgcacgg cttcgtcttg accgactacg cggcggtgca acacttcttc cattttcagc
     2581 aacttgtcac gttcgccttc catcattttt gacacaggaa tgccggtcat acgggaaaca
     2641 acttctgcga tttcctctgc gccgacatta ttacgcaaga gtttgtttgc cggttttgtg
     2701 ctgtccgtat ctgcccgttc ggcggctgca cgctgttttt ccaaatgctc caaatcttca
     2761 tacatcaatt ttgaagccag tgccaaatcg ccttgccgtt ttgcctgttc gattttaatt
     2821 ttgacttcgt caatttgttt cttaatatta gcagcaccgt ctgaaattgc tttttcggct
     2881 ttccagattt cgtctaaatc ggcgtattct ttttgcagac cgttgatttc ctcgtctatc
     2941 agttccaaac gttttttgct ggcatcgtct ttttcttttt caacgtgcgc cttttccatc
     3001 cgaagctgaa ttagacggcg gtcgattttg tccattgctt ccggcttggt ttctttttcc
     3061 atcttgacac ggctggcggc ttcgtcaatc aaatcaatcg ctttatcggg caggaagcgg
     3121 tcggtgatgt agcggtcgct caactccgct gcggcaacga tagcagggtc ggtaatatcg
     3181 ataccatggt ggatttcata acgctcctgt aaaccgcgca aaatagcgat ggtgtcttcc
     3241 acgcttggct cgccaaccaa tactttttgg aaacggcgtt caagtgccgc gtctttttcg
     3301 atgtattggc ggtattcgtc caaggtagtc gcaccgatac agtgcagttc gccgcgtgcc
     3361 aaagccggtt tcaacatatt gcccgcgtcc atcgcgccgt cggttttacc tgcgccaacc
     3421 aaggtatgaa tttcgtcgat gaaaatcaga gtgttgccat cgtctttcgc caagtcgttc
     3481 aacacgcctt tcaagcgttc ttcaaattcg ccgcggtatt tcgcgccggc aatcaatgcc
     3541 gccaagtcca aaaccagtag gcgtttgttg cgcagggatt cgggtacttc gccgttgacg
     3601 atgcgttgtg ccaaaccttc gacgatggcg gttttaccca cgcccggttc gccaatcagc
     3661 acagggttgt ttttggtacg gcgttgcaat acctgaatcg cacggcggat ttcgtcgtca
     3721 cggccgataa cggggtcgag cttaccgtct cgggcgcgtt gggtcagatc gagcgtatat
     3781 tttttcaaag catcgcgttg gtcttcggca ttggcatcgt tcacgttttg tcctcctcgt
     3841 accgcgtcaa tcgcggcatt gatgttttgt tcggtcgcgc cggcttcttt caaaattttg
     3901 ccggccgcat cgttctgctg caccaaggca agcaggaaaa gttcactggc gatataggca
     3961 tcgccgcgtt tggttgcggc tttgtccatc aggttcaaca ccgcctgcaa ttcgcggctg
     4021 ggcagaatgt cgccgccctg gccggacact ttcggcaggc tgttcaaatg ctgctgcaaa
     4081 cgctgtttca cctgcggcac gttcacgccc gcatgagcca agagcgcggc agcaccgctg
     4141 ttttggtcgt caagcagggc tttcagcaca aagcccgctt ccagatagct gctgtccgca
     4201 gccaacgcca aactctgagc ttctgcaagg gcctgttgga atttggcggt taatttgtcg
     4261 tatcgcattt ttgtttcctt ttcaaaatgt ccgctgtcga agcctatatg tgcataattg
     4321 tggataactc aagttctgtt ttctgttttt ctatatttaa ttcgatatat cattgaattt
     4381 aaagtatata aaaatgtata ataatgtgta taactatatc ttcttaatat ggaaaagtct
     4441 gttgtcggct ggatgtaggt ggcaaatcgg gtataatcgg cgcatctttt tccctttcag
     4501 acggcattga tgccgcaagg acatttttat gagcaaaaaa cgagttctga ccggcgtaac
     4561 caccaccggc atcccgcatc tgggcaacta cgtcggtgct atccgccccg ccgtccgcgc
     4621 ggcgcaaaac cctgataccg aatccttcct cttcctcgcc gattaccacg gtatcatcaa
     4681 atgccacgag ccggagatga ttcaccaatc cacccaagcc gttgccgcca cttggcttgc
     4741 ctgcggactc gaccccgagc gcaccacctt ctaccgccaa agcgacattc ccgaagtgat
     4801 ggaattgaac tggattctga cctgcatcac cgccaagggt ttgatgaacc gcgcccacgc
     4861 ctacaaagcc gccgtgcagg caaatgcgga aaacgggcag gaagaccccg atttcggcgt
     4921 ggaaatgggt ttgttcagct atccgattct gatgaccgcc gacatcctta tgttcaacgc
     4981 caacgaagtg cccgtcgggc gcgaccaaat ccaacacgtc gaaatggcgc gcgacatcgc
     5041 cggccgcttc aatcaccgct ttaaagaaat ctttaccctg cccgaagtga aaatcgacga
     5101 aaacgtcgaa ctcttggtcg gtttggacgg acgcaaaatg tccaaatcct acggcaacac
     5161 cattccgctt tgggaaaacg acaaaaaaac ccaaaaatcg gtcaacaaaa tcatcaccaa
     5221 tatgaaagag ccgggcgagc cgaaacagcc cgacgaaagc ccattgtttg aaatctacaa
     5281 agccttctcc acaccgtctg aaacggtgga atttacgaaa atgcttgccg acggcttggc
     5341 ttggggcgag gcaaaaaaac ttttggcggc gaaaatcaac gccgaactcg ccgaaccgcg
     5401 cgaacgctac aacgagctga ccgccgaccc ttcgcaaatc gaagagattt tgcaggcagg
     5461 cgcgcaaaaa gcgcgtaaag aagcacgcga attgttggac aaagtacgcg atgtggtcgg
     5521 catccgcccg ttgaaataaa cccgatgccg tccgaacctc ttaaaggctt gccggaacaa
     5581 aacgtcgtcc ggctgaccgg caagcatccc aacgacttgg aagtcatcag cggcaaatgt
     5641 atggaaaccg acggaaaggg cgcgccttcg ggctgggcgg caaacggcgt gtgccatacc
     5701 ttgtttgcca aactggtggg caatatcgcc gaagacggcg gcaaactgac ggattacctg
     5761 atttcgcatt ccgccctgca accctatcag gcaggcaaaa gcggctatgc cgccgtgcag
     5821 aacggacgct atgtgctgga aatcgacagc gagggggcgt tttatttccg ccgccgccat
     5881 tattgaggta ttcggacatc ccggaatata tttgggtttt tcaaaccttg cgaaaaaagt
     5941 ccgcaccgcc gggaaactca aaaggagggg gatatgtgtt acaattttcc gaactgtttt
     6001 cataaaatag ttttcggacg tgtttcaata tggcattgat gccgccttat tgttcgagaa
     6061 aaaaaccttt atatttaaat ataatgggtt ttaactaaac gggaaaccgt tttctctccg
     6121 gccgatgggc aaaatcagcc gattgatgga acacggttcg atttttaagc aaaaccttaa
     6181 tcaacaactc aagaaggata agacatgaaa aaattattga ttgccgcaat gatggcggct
     6241 gccttggcag cttgttcgca agaagccaaa caggaggtta aggaagcggt tcaagccgtt
     6301 gagtccgatg ttaaagacac tgcggcttct gccgccgagt ctgccgcttc tgccgtcgaa
     6361 gaagcgaaag accaagtcaa agatgctgcg gctgatgcaa aggcaagtgc cgaggaagct
     6421 gtaactgaag ccaaagaagc tgtaactgaa gccaaagaag ctgtaactga agcagctaaa
     6481 gatactttga acaaagctgc cgacgcgact caggaagcgg cagacaaaat gaaagatgcc
     6541 gccaaataat ttgttgcctt ggcaaaaatg atgggatgcc gcctgccggc aacccaaacg
     6601 aaaccgcctg aagattttca ggcggttttt gagttgtatg ccccttgttt tttacgcctg
     6661 catgaccgtt ccgagcagat gtgccgcgca tatcgggatg ttgcggacag ggaaatgccg
     6721 tctgaacatc attcagacgg catttgcccc gcaaggttca gacggcctcg actttgaacg
     6781 gcatattgat tttttgccat tggacgcttt catattccaa tgcgtcggca atcaggggat
     6841 ggcgttccag ccattccctg tcaatacgca ggatgaagcc gcagctttcc gtgtccgtac
     6901 gcaactgcat atttttcggg aaagacaggt cttggcgcga acggcagaac agtgcggcaa
     6961 ggcgcagcga caaaacggca taccacaaca tttcgttggt gccgatgatg ccgctcattt
     7021 ttttcatatc gccgcgatga ccgatgacca gttgggcaag tatggtctgt tctttgcgtg
     7081 agaaacccgg catatcggcg ttttcgagga tgtaggcgga atgcttgtga tagccggtgt
     7141 gggcgatgtc caaaccgatt tcgtgcagcg cggcggcgcg tccgagatac tgttgccaca
     7201 aggcaagctc ttgaaccgta acatttttag cgtggcagag gctgtccata aaggtttgcg
     7261 cggtctcggc ggtgcgtttc gcctgattga ggctgacgtg gtagcggtgt tggaactcgg
     7321 caaccgtttg tccgcgcata tcttcgttta aaccgcgccc gatcaaatcg taaaacacgc
     7381 cgtcgcgcag ggcggcttcg gttacggtca tcctgtcgag tttcatttct tcaaacgccg
     7441 ccatcatcac ggcaagtccg ccggcaaaaa cttcgatgcg ttccggtttc aggttttcaa
     7501 atttggcttt tttgaccgaa ccggcttcga tgatgcgttc ggcgagggcg cgcatgcctt
     7561 tgtaggtaat gtccgcctct tggggcattt cggcggcaag cacgtcgcgg atggattttg
     7621 ccgaacccga tgtgccgacg gcgaaatccc aaccttcgcg cctcatattt ttgctgatgc
     7681 gctggatttc gttgcgggcg gcggaaatgg cagattggaa gtctttggcg gtgattttgt
     7741 tttggaagaa gcgcaggctg taggttacgc agcccaaggg caggctttca gtaatgtcgg
     7801 gattcagcgt cgagccgatg acaaattctg tcgaaccgcc gccgatgtcg ataaccagca
     7861 ttttgccgcc gcccgggggg agggtgtgga tcacgccggt ataaatcagc cgcgcctctt
     7921 cgcgcccggc gatgatttcg atggggaaac ccagtgccgc ttcggctttg ggaaggaaat
     7981 ctgcgatgtt tttggcgacg cggaatgtat tggttgccac ggcgcgtacc tgttcagggc
     8041 ggaagccgcg caggcgttcg ccgaattttg ccagacagtc caaagcctgt tcttgggaag
     8101 cggcactcag gtttttctgt tcgtccagtc cggcggcgaa gcgcaccatc tgtttgaacg
     8161 aatcgatgac ttttaattgt ccgttgttgt tttcgcaaat ctggaggcgg aaactgttgg
     8221 aacccaaatc gacggaggcg aggatgtttg cgggggtggt ggtcatggcg gatatcggtg
     8281 ggggaaaaac gcaatgttac tctgacggcg caggcgttga caataaatga tgcggcggtt
     8341 tttgattctg tccacggatg ttgccgacgg cattttttgc gcttatttga aatccttttc
     8401 cacgctcatg aaaatctgcg tgtttttgcg tgtgtaaaaa cttttcatat tgctgtcgat
     8461 tttcagatag cggaaattga gttgcggcgt aaagcccttc caagagattt tgtcgtgcca
     8521 aaacgacagg tttgcctgat attcgtggtc tttgcgcggg aagcggtaca caatggtccc
     8581 gggcgcgtca aacgtcctgc gtgtatagcg caggtttgcc cgcagaccca agccgccgtc
     8641 gaacgttttg accgcgccga tacgcaaacc cttgcggacg gaagcctgtt ccgcctcctt
     8701 cgtcaagtcg tgcgaccagt ccgccccgcc gtaaagcagc cagtctttcg gcgcggaata
     8761 catcagcgtc gcgcccgcca gcggcatatg gctgtcgtat cgggcggcgg tgcggtcttc
     8821 ctgataatgc ttccacatat tgcccgcgtt tagtgtcaac cgccagcgtt cgctcaagtg
     8881 ttgggagaaa tcggcattaa agccgccgac gaaattgtat cggctgccgc ctaagaggtt
     8941 ttgcccgaca aacggcacga tgccgaacga gcgcgttacc gaacgatttt tatagccgag
     9001 cgacaggtgc aggcactgtt cgctgaaatc tttgttatcc caataatgca cgccgccgcc
     9061 gctgatgccg ccgtagagga aatgatgccc gcccgcattg atttcgcgcg acacgcctaa
     9121 gccctagcgc aaaccgtgtg ccttttgcgg caggctgtcg gcggttttcg tccagcttct
     9181 gcccgcaaat tcaatcgttt ttttggacga agcgttgttt atagcggatt aacaaaaatc
     9241 aggacaaggc gacgaagcct cagacagtac agatagtacg gaaccgattc actcggtgct
     9301 tcagcacctt agagaatcgt tctcttcgag ctaaggcgag acaacgccgt accggttttt
     9361 gtt
//
LOCUS       DAXIDM010000074         9245 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000074 DAXIDM010000000
VERSION     DAXIDM010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9245
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.074"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(44..3076)
                     /locus_tag="ACFOAE_001492"
     CDS             complement(44..3076)
                     /locus_tag="ACFOAE_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015616 - DNA translocase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFC6884957.1"
                     /translation="MFWIVLIVILLLALAGLFFVRAQSEREWMREVSAWQEKKGEKQA
                     ELPEIKDGMPDFPELALMLFHAVKTAVYWLFVGVVRFCRNYLAHESEPDRPVPPASAN
                     RADVPNASDGYSDSGNGTEEAETEAAEAAEEEAADTEDIATAVIDNRRIPFDRSIAEG
                     LMPSESEISPVRPVFKEITLEEATRALNGAALRETKKRYIDAFEKNETAVPKVRVSDT
                     PMEGLQIIGLDDPVLQRTYSRMFDADKEAFSESADYGFEPYFEKQHPSAFSAVKAENA
                     RNAPFRRHAGQAEAKSPDVSQGQSVSDGTAVRDACRRVSVNLKEPNKATVSAEARISR
                     LIPESRTVVGKRDVEMPSETENVFTETVSSVGYGGPVYDEAADIYIEEPAAPDAWVVE
                     PPEVPKVPMPAIDIPPPPPVSEIYNRTYEPPAEFEQAQRSRIAETDHLADDVLNGGWQ
                     EETAAIADDGSEGAAERSSGQYLSETEAFGHDSQAVCPFENVPSERPSCRVSDTEADE
                     GAFQSEETGAVSEHLPTTDLLLPPLFNPEATQTEEELLENSITIEEKLAEFKVKVKVV
                     DSYSGPVITRYEIEPDVGVRGNSVLNLEKDLARSLGVASIRVVETIPGKTCMGLELPN
                     PKRQMIRLSEIFNSPEFAESKSKLTLALGQDITGQPVVTDLGKAPHLLVAGTTGSGKS
                     VGVNAMILSMLFKAAPEDVRMIMIDPKMLELSIYEGIPHLLAPVVTDMKLAANALNWC
                     VNEMEKRYRLMSFMGVRNLAGFNQKIAEAAARGEKIGNPFSLTPDDPEPLEKLPFIVV
                     VVDEFADLMMTAGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRI
                     AFQVSSKIDSRTILDQMGAENLLGQGDMLFLPPGTAYPQRVHGAFASDEEVHRVVEYL
                     KQFGEPDYVDDILSGGSSEELPGIGRSGDGETDPMYDEAVSVVLKTRKASISGVQRAL
                     RIGYNRAARLIDQMEAEGIVSAPEHNGNRTILVPLDNA"
     gene            3241..3921
                     /locus_tag="ACFOAE_001493"
     CDS             3241..3921
                     /locus_tag="ACFOAE_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000041 - transition metal ion transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HFC6884958.1"
                     /translation="MIFQTVWFSDVVLSVSWIVLILILAASAPSAFRSLARYRSALPL
                     CTVIFSAAWCLNASAGGGQLAQMNYHLLAVNLVALMVGTSAAFWLAALLMLPYCLLFA
                     GSAGAYPPNALVLILPALAVNRLSRMLVNRLPPNIFIFIFVNGFLASAAGILLTGLVL
                     TGILDAANAFPSEILWTTALPVFILLAWAEAFLSGISTAIFVALKPHWINTFDDNRYL
                     KSDRGIWR"
     gene            3950..4309
                     /locus_tag="ACFOAE_001494"
     CDS             3950..4309
                     /locus_tag="ACFOAE_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HFC6884959.1"
                     /translation="MLSNIIPLSIGAALGATARWLLNLAVPASLSPATGNLFANWTGA
                     LLIGIFAETVNHPQWKLLLITGFLGSLTTLSGFSLETVTLLQSNRPASALANIFLHTA
                     GSLLLTWLGLKIGTAVK"
     gene            complement(4963..5499)
                     /locus_tag="ACFOAE_001495"
     CDS             complement(4963..5499)
                     /locus_tag="ACFOAE_001495"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFC6884960.1"
                     /translation="MDLREVKLGGETIYEGGFVSISRDKVRLPNGNEGQRIVIRHPGA
                     ACVLAVTDEGKVVLVRQWRYAANQATLELPAGKLDVAGEDMAACALRELAEETPYVAD
                     SVRLLYSFYTAVGFCNEKMYLFEAESVRLGSTLANDEDEITETVLMSKEEVRQALAND
                     EIKDGKTLIGLQYWLMKD"
     gene            complement(5533..5889)
                     /gene="folB"
                     /locus_tag="ACFOAE_001496"
     CDS             complement(5533..5889)
                     /gene="folB"
                     /locus_tag="ACFOAE_001496"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004150 - dihydroneopterin aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006760 - folic acid-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HFC6884961.1"
                     /translation="MDKIFLHGMKADTLIGVYGWERERLQTLIVDLDIGIPEKAGSDD
                     DIANTVHYAEVCETLRRHLKEQDFLLLEALAEYIADLVLGYFGAVWVRVKIVKPGILE
                     GVREVGVEIERGKRED"
     gene            5945..6547
                     /gene="plsY"
                     /locus_tag="ACFOAE_001497"
     CDS             5945..6547
                     /gene="plsY"
                     /locus_tag="ACFOAE_001497"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFC6884962.1"
                     /translation="MFNISAVAVSYLIGSLSFAVIVSKYYGMDDPRTYGSGNPGATNV
                     LRSGKKKAAALTLLGDAAKGLVAVLLARVLQEPLGLSDSAIAAVALAALVGHMWPVFF
                     GFKGGKGVATALGVLLALSPATALVCALIWLVMAFGFKVSSLAALTATIAAPLAALFF
                     MPHTSWIFATLAIAILVLLRHKSNILNLIKGKESKIGEKR"
     gene            6635..7480
                     /locus_tag="ACFOAE_001498"
     CDS             6635..7480
                     /locus_tag="ACFOAE_001498"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008988 - rRNA
                     (adenine-N6-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
                     /protein_id="HFC6884963.1"
                     /translation="MLSYRHAFHAGNHADMLKHFTLFLVLQYFNRKDKPYWYIDTHGG
                     AGVYNLEGSEAQKVGEYRQGIALLRQAQNLPAELSDFAAHIQKILPSPELYCGSPWLA
                     QSLTRVGDKLRLFELHPTDFVHLQNNMGEAGLGKRGQVLREDGYKGLISLLPPPPRRA
                     AVLIDPPYEEKQDYWRVTETLKSALKRFESGCYLIWYPCLSREESRKLPEELKKLVPD
                     NYLHAELHVHAPKADGFGMHGSGMFVINPPYLLAEQLAANLPALTRLLAQDEGARYLL
                     DSKIR"
     gene            7726..8700
                     /locus_tag="ACFOAE_001499"
     CDS             7726..8700
                     /locus_tag="ACFOAE_001499"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HFC6884964.1"
                     /translation="MDTLTRFLPEHLQQNQLPEALGGVLLSVVSACTEINAKVRLGAL
                     AGVLGMAGTGNIQGEDQKKLDVIANNIMIDTLKANPAVAGLASEEEDSFVSAGENGRY
                     LVLFDPLDGSSNIDVNISVGTIFSILEKPEGALATESFLQTGRQQLAAGYILYGPQTQ
                     LVFTFGHGVYMFTLNAENEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELL
                     AGETGTRGKNYNMRWVASMVAEIHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMS
                     LILEQAGASASNAYQAMLDIQPENLHQRVAVFMGSSEEVAYLDRLHAK"
     gene            complement(8843..9061)
                     /locus_tag="ACFOAE_001500"
     CDS             complement(8843..9061)
                     /locus_tag="ACFOAE_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HFC6884965.1"
                     /translation="MFPEYRDLISKLKQENSRFARLFDEHNELDDKITGLVNNPVTSG
                     AETIDELKKAKLKLKDELYAILQKAAGK"
     gene            complement(9037..>9245)
                     /locus_tag="ACFOAE_001501"
     CDS             complement(9037..>9245)
                     /locus_tag="ACFOAE_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884966.1"
                     /translation="GKAENLCVKRDIVNVFINRTAVLKENFAVSDKTLDKNIIFVIIN
                     VKIQFDFLTVNQERKAICSQNTVI"
BASE COUNT         2150 a         2728 c         2141 g         2226 t
ORIGIN      
        1 ccgtctgaaa cagtcttcag acggcatttc catttgcaaa aaatcaagca ttgtccaagg
       61 ggacgagaat cgtacggttg ccgttgtgtt ccggtgcgga cacaatgcct tccgcctcca
      121 tctggtcaat cagacgcgcg gcgcggttgt agccgatacg caaggcgcgc tgtacgcccg
      181 aaatactggc tttgcgcgtt ttcaggacaa cggatacggc ttcatcatac atcggatcgg
      241 tttcgccgtc gccgctgcgc ccgatgccgg gcagctcttc gctgctgccg ccgctcaaaa
      301 tatcgtcaac atagtccggc tcgccaaact gtttcaaata ttcgaccacg cggtgcacct
      361 cttcatccga ggcaaacgcg ccgtgaacgc gctgcggata ggcagtaccc ggcggcagga
      421 acagcatatc gccctgaccg agcaggtttt ccgcgcccat ttggtcgaga atcgtgcggc
      481 tgtcgatttt gctggacact tggaacgcga tacgcgtcgg gatgttcgcc ttaatcagac
      541 ccgtgatgac atcgacgctg gggcgttgtg tggcaaggat aagatggatg cctgccgcgc
      601 gggctttttg ggcgaggcgg gcaatcagtt cctcgatttt cttgcctgcc gtcatcatca
      661 aatcggcaaa ctcatcgacc acgaccacga taaacggcag tttttccaaa ggttcgggat
      721 cgtcgggcgt gaggctgaac ggattgccga ttttttctcc ccttgctgcg gcttcggcga
      781 ttttttgatt gaagcccgca agattacgca cgcccataaa gctcatcagg cggtagcgtt
      841 tttccatttc gttaacacac cagttcagcg cgtttgccgc cagcttcata tcggtaacga
      901 caggggcgag caggtgcggg atgccttcgt aaatgctcaa ttccagcatt ttcggatcga
      961 tcataatcat acgcacgtct tccggcgcgg ctttgaaaag catagacaga atcatcgcgt
     1021 tgacacccac cgatttgccc gaaccggtcg tgccggcaac caacaaatgc ggcgcttttc
     1081 ccaagtcggt tacgacgggc tgtccggtga tgtcctgacc gagcgcgagc gtcagcttgg
     1141 atttggattc ggcaaactcg ggcgaattga agatttcgct caggcgtatc atttggcgtt
     1201 tcgggttcgg aagttccaaa cccatacagg ttttgccggg gatggtttcg acaacgcgga
     1261 tggaagccac gccgagcgaa cgcgccaagt ctttttccag attcagaacg gaattgccgc
     1321 gcacgccgac atcgggttcg atttcataac gcgtaatcac ggggccggaa taagaatcga
     1381 caaccttgac cttgactttg aactccgcca atttttcttc gatggtgatg ctgttttcca
     1441 acagttcttc ttcggtttgc gtcgcctcgg gattgaacag cggcggcaga agcaggtcgg
     1501 ttgtcggcag gtgttcggat accgcaccgg tctcttccga ttggaacgcc ccttcatccg
     1561 cttccgtatc cgatacccgg caggacgggc gttcagacgg cacattttca aacggacaaa
     1621 ccgcctgact gtcatgcccg aacgcttcgg tttccgacag atattgcccg cttgaccgct
     1681 ctgccgcacc ttcactgccg tcatctgcaa tagcggcggt ttcctcctgc caacctccat
     1741 tcaaaacatc atcggcaaga tggtcggttt cggcaatgcg gctgcgttgc gcctgctcga
     1801 attctgccgg cggttcatag gtacggttgt agatttccga tacgggaggc ggcggcggaa
     1861 tatcgattgc gggcatggga actttcggca cttcgggtgg ttcgaccacc caagcatcgg
     1921 gcgcagcagg ttcttcaata tagatatcgg cagcttcatc ataaaccgga ccgccgtatc
     1981 ccacagacga aacggtttcc gtgaaaacat tttcggtttc agacggcatt tcgacatccc
     2041 gtttcccgac aaccgtccga ctttccggaa tcaggcgcga aatccgcgcc tccgcagaaa
     2101 ccgttgcctt gttcggttct ttcaaattga cggaaacgcg gcggcaggca tcgcggacgg
     2161 ctgtgccgtc tgaaacggac tgtccttggg aaacatccgg ggattttgcc tccgcctgcc
     2221 ctgcatgacg gcggaacggc gcattccgtg cattttcggc tttgactgca gaaaaggcag
     2281 acggatgctg cttctcaaaa tacggctcaa atccgtaatc cgcagactcg gaaaacgctt
     2341 ctttgtccgc atcgaacata cgggaatacg tgcgttgaag cacagggtcg tccaaaccga
     2401 taatctgcag cccttccatc ggggtatcgg acacgcggac tttggggacc gctgtttcgt
     2461 ttttctcaaa tgcatcgata tagcgttttt tcgtttccct taaagccgcg ccgtttaagg
     2521 cacgcgttgc ttcttccaaa gtgatttcct taaaaaccgg acggacgggc gaaatttcgc
     2581 tttcagacgg catcaaccct tcagcaatac tccggtcgaa tgggatgcgg cggttgtcga
     2641 ttacggcagt tgcaatgtct tccgtatcgg cagcctcttc ctccgcagct tctgctgctt
     2701 ccgtttccgc ttcttccgtc ccgtttccac tgtctgaata tccgtcggat gcgttcggaa
     2761 catccgcacg gtttgcagaa gcaggcggaa caggcctatc cggttcggat tcgtgcgcca
     2821 gatagtttcg gcagaaacgg acgacaccga cgaacagcca atacactgcc gttttgacgg
     2881 catggaaaag catcagggca agttcgggaa aatcgggcat accgtctttg atttcaggca
     2941 gctccgcctg tttttcccct ttcttttcct gccacgcaga aacctcgcgc atccactcgc
     3001 gttcggattg tgcgcggaca aaaaacaggc cggcaagcgc aagcaacaaa ataacgatca
     3061 aaactatcca aaacatatgc cgtttcccgc aagacaaacg attaaacggg tttattttaa
     3121 cgtgtttcca tcccaaaaaa aacaaccagc cggcaattct gccgaaaccg attcggcttt
     3181 cggtttgccc ccgccgacag tataatagcc gtcccttccc ttaatctttg cggcattgcc
     3241 atgattttcc aaacagtctg gttttcagat gtggtactgt cggtttcgtg gattgtcctt
     3301 atcctgatac tggcagcttc cgcgccgtcc gcattccgct cgcttgcccg ctaccgttcc
     3361 gcccttccac tgtgtaccgt aattttttcc gcagcatggt gtctgaacgc ctctgccggc
     3421 ggcggacagc ttgcccagat gaactaccat ctgctcgccg tcaatctggt tgcactgatg
     3481 gtgggcactt ccgccgcctt ttggcttgcc gcgctgctga tgctgcccta ctgcctgctg
     3541 tttgccggtt ctgccggcgc atatccgccg aacgctttgg tgctgattct gcccgcgctt
     3601 gccgtcaacc gcctgtcgcg tatgctggtc aaccgcctgc cgcccaatat tttcatcttt
     3661 attttcgtca acggctttct cgcttccgcc gccggcattc tgttgaccgg gctggtgctg
     3721 accggtattt tggatgctgc aaacgctttt ccgtccgaaa tattgtggac gaccgccctg
     3781 cccgtcttta ttctgctggc gtgggcggaa gccttcctca gcggcatttc aactgccata
     3841 tttgttgcac tgaagcccca ttggattaac actttcgacg acaaccgcta tcttaagtcc
     3901 gaccgcggca tatggcggta gccttcagac ggcatagaca ggcaaaacca tgctttccaa
     3961 catcatcccc ctttccatcg gtgcggcact cggtgcaacg gcgcgttggc tgctcaacct
     4021 cgccgttccc gcatcgttgt ctcccgccac gggcaacctg tttgccaact ggacgggcgc
     4081 gctgctcatc ggcatctttg ccgaaaccgt caaccatccg caatggaagc tgctgctgat
     4141 taccggtttt ctcggcagcc tgaccacgct ttccggattt tcactggaaa ccgtaaccct
     4201 gctccaatcg aatcgtcctg cttcagcact tgccaatatt ttcctgcaca cggcaggttc
     4261 gctgctgctg acttggctcg ggctgaagat agggacggca gtcaaataac cgcaacaaat
     4321 tgcctccctt tgttttgaca taatctataa attagcttcg cttgtttaaa tactggctgt
     4381 gccaattata gtagattaac aaaaatcagg acaaggcgac gaagccgcag acagtacaaa
     4441 tagtacggaa ccgattcact tggtacttca gcaccttaga gaatcgttct ctttgagcta
     4501 aggcgaggca acgccgtact ggtttttgtt aatccactat accgttctca aattcaaatt
     4561 gggcttttag gtctataaca aagaaaaagc cttggtagga taaacctacc aaggcttttt
     4621 cttaaaaaaa cgctctatta ccgtgcctaa aaatgcaaaa aagtaaccgt cataaccctt
     4681 ttgccaaaat caatatcatc atccgatgaa tgaattgacg gtatataaga aagaattaat
     4741 aagctcataa accggtaaga aaaatcagta acaaagatat tcattattaa ccattttaaa
     4801 aattatcatg ttcgtttggg taattattat acccttttcc ctcttattac taaagcacga
     4861 atgactttaa aggacgcgcc cagatacaag ccgaaaaggc atatcccatc cgctaaacaa
     4921 accgcccgcc gatccaatcc ggcgggcaag tccaacatcc tgtcaatcct tcatcaacca
     4981 gtattgcaaa ccgattaatg tcttgccgtc tttaatttca tcgtttgcca atgcctgacg
     5041 gacttcttct ttcgacatca atacggtttc cgtaatctcg tcttcgtcat tggcaagcgt
     5101 actgcccaag cgcacgcttt ccgcttcgaa cagatacatt ttttcattgc aaaaaccgac
     5161 cgccgtataa aaactgtaca acaggcgcac gctgtcggca acataaggtg tttcctccgc
     5221 caattctcgc agcgcacacg ctgccatatc ctcgcccgcc acatccagct tgcccgcagg
     5281 aagttccaat gtcgcctgat ttgccgcata acgccactgc cgcaccaaaa ccactttccc
     5341 ctcgtccgta accgccaaca cgcacgccgc acccggatgg cggatgacga tacgttgccc
     5401 ttcattgccg ttgggcaacc tgaccttatc cctgctgatg ctgacgaaac cgccctcgta
     5461 aatggtttcg ccgcctaatt ttacttccct caaatccact tcatatctcc tttccgtttc
     5521 ctattatgcc gttcaatctt cacgcttgcc gcgctcgatt tccacgccaa cctcgcgcac
     5581 gccttctaaa atacccggct tgacgatttt cacgcgtacc cacaccgcgc cgaaatatcc
     5641 caaaaccaaa tcggcaatat attccgccaa cgcttccaaa agcaggaaat cctgttcttt
     5701 cagatgtcgg cgcaatgttt cgcatacctc ggcataatgc accgtattgg caatatcgtc
     5761 gtccgaaccc gctttctcgg gaatgccgat gtccaaatcg acaatcaggg tctgcaaccg
     5821 ttcgcgctcc cagccgtaca cgccgataag cgtatccgcc ttcataccgt gcaaaaagat
     5881 tttatccata atccgccccg ttttttgcta aaataaccgc accattctaa gtaaagtacc
     5941 gcaaatgttc aacatatcgg ctgttgccgt ttcctatctg atcggctcac tttctttcgc
     6001 cgtcatcgtg tccaaatatt acggcatgga cgacccgcgc acctacggat cgggcaatcc
     6061 gggggcaacc aatgttttac gcagcggcaa aaaaaaggcg gccgcgctga cgctcttggg
     6121 cgatgccgcc aaaggtttag ttgccgtttt gcttgcacgc gtgcttcaag aaccgctcgg
     6181 tttatccgac agcgcaatcg cggccgtcgc actcgccgcg ctggtcgggc atatgtggcc
     6241 ggtgtttttc ggatttaaag gcggcaaagg cgtggcaacg gcattgggcg tgcttctggc
     6301 actctctcct gcaactgcct tggtctgcgc gttgatttgg cttgtgatgg cattcggctt
     6361 caaagtatcc tcccttgccg cattaaccgc cacaatcgcc gccccccttg ccgcactgtt
     6421 ttttatgccg catacttctt ggattttcgc aaccctcgca atcgccatat tggtgttgct
     6481 ccgccataag agcaacatcc tcaacctgat taaaggcaaa gaaagcaaaa tcggtgaaaa
     6541 acgctgattc ggcatttgtt ttccattacg tcatgccgtc tgaaaccatg ttcccgcgtt
     6601 cagacagcat ttccgcacaa acggctttca taccatgctc agttacagac acgcattcca
     6661 cgccggcaac cacgccgata tgctcaaaca ctttaccttg tttttagtgc tgcaatattt
     6721 caaccgcaaa gacaagccct actggtacat cgacacgcac ggcggcgcgg gtgtgtacaa
     6781 tctcgaaggc agcgaggcgc agaaagtcgg cgaataccgg caaggcatcg ccctgctccg
     6841 acaggcgcaa aacctgcctg ccgaactctc tgactttgcc gcgcacatac aaaaaatcct
     6901 gccctcgccc gaactttact gcggttctcc gtggctggca caatcgctga cccgcgtcgg
     6961 cgacaaatta cgcctgtttg agctgcaccc caccgacttt gtccatctgc aaaacaatat
     7021 gggcgaagca ggattgggca aacgcggaca agtgttgcgc gaagacggtt acaaagggct
     7081 gatttccctg ctgccgcccc cgccgcgccg tgccgccgtc ctcatcgacc cgccttacga
     7141 ggaaaaacag gactactggc gtgtaacgga aacgctgaaa tccgctttaa aacggtttga
     7201 gtccggctgt tatctcatct ggtatccctg cctcagccgc gaagaaagcc gcaagctgcc
     7261 cgaagaactg aaaaaactcg ttcccgacaa ctaccttcac gccgaactgc acgtccacgc
     7321 gccgaaagcc gacggtttcg gtatgcacgg cagcggaatg ttcgtcatca atccgcccta
     7381 tctgttggcg gaacaattgg cggcaaacct ccccgccctg acgcggctgc tggcgcaaga
     7441 cgaaggcgcg cgctaccttt tggacagcaa aatccgctga ccccgatgcc gtctgaaacc
     7501 cttcagacaa catctcccgt caaataaaca aaaccggacg atataccggc agtcggcact
     7561 tttaagaata aatatcccct catccgcctg ccgcgttccg acttgcccca tgccgttttt
     7621 ttacactaca atcccctaga ctatcctgca aaacgcacca aaggaatacg ccacaataac
     7681 ctgccgcctt tcagacggca caaacctttc cgaaacgagc aaactatgga cacactgacc
     7741 cgattcctcc ccgaacacct gcaacaaaac cagctgcccg aagcactcgg cggcgtttta
     7801 ctgtccgttg tttccgcctg caccgaaatc aacgccaaag tccgcctcgg cgcactggcc
     7861 ggcgtattgg gtatggcggg cacgggcaat attcagggcg aagaccaaaa aaaactggat
     7921 gttatcgcca acaacatcat gattgacaca ctcaaagcca accctgccgt tgccggtttg
     7981 gcaagcgagg aagaagactc tttcgtaagt gccggtgaaa acggacgcta tctcgtccta
     8041 ttcgaccctt tagacggatc gtccaatatt gatgtcaaca tttccgtcgg tacaattttc
     8101 tccatccttg aaaaacccga aggcgcattg gcaaccgaat cattccttca aacgggcaga
     8161 cagcagcttg ccgcaggcta tatcctctac gggcctcaaa cccagctcgt attcacattc
     8221 ggacacggcg tatatatgtt cacgctcaat gccgaaaacg aatttgtgct gaccaaagaa
     8281 aaaccgaaag tacccgaaag taccaaagaa tttgccatca atatgtccaa ccgccgccac
     8341 tggctgcccc ccgtccaaca atacatcgac gagctcttgg cgggcgaaac cggcacgcgc
     8401 ggcaaaaact acaatatgcg ctgggtagcc agcatggttg ccgaaatcca ccgcatcctg
     8461 atgcgcggcg gcgtgttcat gtatccgcaa gacaaacgcg accccgccaa gcccggcaaa
     8521 ctgcgcctga tgtacgaagc caaccctatg agcctgatac tcgaacaggc gggcgcatcg
     8581 gcaagcaacg catatcaagc catgctcgac atacagcccg aaaacctgca ccaacgcgtc
     8641 gccgtcttca tgggcagcag cgaagaagtc gcctatctcg accgcctgca cgcaaaatag
     8701 acagacagcc gttcacacaa gtacacggcg gcggcaatcc gataccgccg ccgttatttc
     8761 aaacagcaca agccttctgg tcaaatgaca aaaatgccgt ctgaaaacat ttcagacggc
     8821 atttcaaaaa ctcaaacccg aattattttc ccgctgcttt ttgcaggatg gcgtacaact
     8881 cgtctttcag tttcaatttg gcttttttca gctcatcgat ggtttccgca ccgctggtaa
     8941 ccggattgtt gaccagaccg gtaattttat cgtccagctc gttgtgttcg tcgaacagac
     9001 gggcgaagcg ggaattttcc tgtttcaatt tggaaatcaa atcacggtat tctgggaaca
     9061 tatcgctttc ctctcttggt ttacggttaa aaagtcaaac tgaatcttta cattaattat
     9121 aacaaagata atatttttat ccagtgtttt atcggatacg gcaaaatttt cttttaacac
     9181 cgccgtccgg ttgataaaaa cgttgacaat atcacgcttt acgcataaat tttcagcctt
     9241 tccta
//
LOCUS       DAXIDM010000075         9141 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000075 DAXIDM010000000
VERSION     DAXIDM010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9141
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.075"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(146..2749)
                     /gene="pepN"
                     /locus_tag="ACFOAE_001502"
     CDS             complement(146..2749)
                     /gene="pepN"
                     /locus_tag="ACFOAE_001502"
                     /EC_number="3.4.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016688050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HFC6884967.1"
                     /translation="MSKTVRYLKDYQTPAYRILETDLHFDIAEPQTVVKSRLTVEPQR
                     VGEPLVLDGSAKLLSVKINGAAADYMLEGETLTIADVPSERFTVEVETEILPAENKSL
                     MGLYASAGNLFTQCEPEGFRKITFYIDRPDVMSKFTTTIVADKKRYPVLLSNGNKIDG
                     GEYSDGRHWVKWEDPFAKPSYLFALVAGDLAVTEDYFTTMSGRNVKIEFYTAEADKPK
                     VGFAVESLKNAMKWDETRFGLEYDLDIFMVVAVGDFNMGAMENKGLNIFNTKFVLADS
                     RTATDTDFEGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSGDRASRA
                     VRRIENIRLLRQHQFPEDAGPTAHPVRPASYEEMNNFYTMTVYEKGAEVVRMYHTLLG
                     EEGFQKGMKLYFQRHDGQAVTCDDFRAAMADANGINLDQFALWYSQAGTPVLEAEGRL
                     KNNSFELTIKQTVPPTPDMADKQPMMIPVKVGLLNRNGEAVAFDYQGKRATEAVLLLT
                     EAEQTFQFESVTEAVVPSLLRGFSAPVHLNYPYSDDDLLLLLAHDSDAFTRWEAAQTL
                     YRRAVAANLAALSDGIELPKHEKLLAAVEKVISDDLLDNAFKALLLGVPSEAELWDGA
                     ENIDPLRYHQAREALLDTLAVRFLPKWHELNRQAAKQENQSYEYSPEAAGWRTLRNVC
                     RAFVLRADPAHIETVAEKYGEMAQNMTHEWGILSAVNGNESDTRNRLLAQFADKFSDD
                     ALVMDKYFALIGSSRRSDTLQQVQTALQHPKFSLENPNKARSLIGSFSRNVPHFHAED
                     GSGYRFIADKVIEIDRFNPQVAARLVQAFNLCNKLEPHRKNLVKQALQRIRAQEGLSK
                     DVGEIVGKILD"
     gene            complement(2960..3754)
                     /locus_tag="ACFOAE_001503"
     CDS             complement(2960..3754)
                     /locus_tag="ACFOAE_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002252744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFC6884968.1"
                     /translation="MTTILAFDIETVPDVQGIRTLYELPSSLPDDEVVLFAQQKRRAQ
                     TGGDFMQHHLHQIVAISCCMRWGQDKVHVGTIGEMDDGEEVVIAKFFELIEKHTPQLV
                     SWNGGGFDLPVLHYRSLIYGINAARYWDMGDGDFGDSRDFKWNNYISRYHQRHCDLMD
                     LLALYQPRANVPLDDMAKLCGFPGKLGMDGSKVWDAFHAGRLKEIRNYCETDAVNTYL
                     MYLRFCLVSGRFDADEYEMEIKRIRNYLSAQTEDKPHWAEFVQAWK"
     gene            complement(3870..4004)
                     /locus_tag="ACFOAE_001504"
     CDS             complement(3870..4004)
                     /locus_tag="ACFOAE_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884969.1"
                     /translation="MPSERIFRSILRLVGVSSETVKQKFAGVELSYAGKAAGESLYCL
                     "
     gene            complement(4504..5373)
                     /locus_tag="ACFOAE_001505"
     CDS             complement(4504..5373)
                     /locus_tag="ACFOAE_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A biosynthesis lauroyl acyltransferase"
                     /protein_id="HFC6884970.1"
                     /translation="MKFIFFVLYVLQFLPFALLHKIADLTGLLAYLLVKPRRRIGEIN
                     LVKCFPEWSEEKRKTVLKQHFRHMAKLMLEYGLYWYAPAGRLKSLVRYRNKHYLDDAL
                     AAGEKVIILYPHFTAFEMAVYALNQDVPLISMYSHQKNKILDEQILKGRNRYHNVFLI
                     GRTEGLRALVKQFRKSSAPFLYLPDQDFGRNDSVFVDFFGIQTATITGLSRIAALANA
                     KVIPAIPVREADNTVTLHFYPAWESFPSEDAQADAQRMNRFIEERVREHPEQYFWLHK
                     RFKTRPEGSPDFY"
     gene            complement(5424..5960)
                     /gene="ruvC"
                     /locus_tag="ACFOAE_001506"
     CDS             complement(5424..5960)
                     /gene="ruvC"
                     /locus_tag="ACFOAE_001506"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFC6884971.1"
                     /translation="MSATVRILGIDPGSRVTGFGIIDVRGRDHFYVASGCIKTPADAP
                     LADRIAVIVRHIGEVVTVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLP
                     VSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHG
                     LASRLNPSGMQVKRGRFQ"
     gene            complement(5963..6202)
                     /locus_tag="ACFOAE_001507"
     CDS             complement(5963..6202)
                     /locus_tag="ACFOAE_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HFC6884972.1"
                     /translation="MPHTLPDISQCIRQNLEQYFKDLNGTEPCGVYDMVLHQVEKPLL
                     VCVMEQCGGNQSKASVMLGLNRNTLRKKLIQHGLL"
     gene            complement(6232..7242)
                     /gene="dusB"
                     /locus_tag="ACFOAE_001508"
     CDS             complement(6232..7242)
                     /gene="dusB"
                     /locus_tag="ACFOAE_001508"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFC6884973.1"
                     /translation="MHIGGYFIDNPIALAPMAGITDKPFRRLCRDFGAGWAVCEMLTS
                     DPTLRNTKKTLHRSDFADEGGIVAVQIAGSDPQQMADAARYNVSLGAQLIDINMGCPA
                     KKVCNVQAGSALMQNEPLVAAILEAVVRAAGVPVTLKTRLGWHDDHQNLPVIAKIAED
                     CGIAALAVHGRTRTQMYKGEARYELIAETKCRLNIPVWVNGDITSPQKAQAVLKQTAA
                     DGIMIGRGAQGRPWFFRDLKHYAEHGVLPPALSLAECAAAILNHIRAIHAFYGDSAGV
                     RIARKHIGWYIGEMPDGEQARREINRLDSAAAQYDMLAGYLERLAGKTDRWACGYRTN
                     AF"
     gene            7608..8981
                     /locus_tag="ACFOAE_001509"
     CDS             7608..8981
                     /locus_tag="ACFOAE_001509"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFC6884974.1"
                     /translation="MSNPFSSLGLGTELVSALTAQGYENPTPIQAAAIPKALAGHDLL
                     AAAQTGTGKTAAFMLPSLERLKRYATASTSPAMHPVRMLVLTPTRELADQIDQNVQGY
                     IKNLPLRHTVLFGGMNMDKQTADLRAGCEIVVATVGRLLDHVKQKNIHLNKVEIVVLD
                     EADRMLDMGFIDDIRKIMQMLPRQRQTLLFSATFSAPIRKLAQDFMNAPETVEVAAQN
                     TTNANVEQHIIAVDTIQKRNLLERLIVDLHMNQVIVFCKTKQSVDRVTRELVRRNLSA
                     QAIHGDRSQQSRLETLNAFKDGNLRVLVATDIAARGLDIAELPFVINYEMPAQPEDYV
                     HRIGRTGRAGADGVAISLMDESEQKMFESIKELTGNKLLIERIEGFEPQWWEQGGAKP
                     EKPEMREPRQRNRYESAKAQREKNTRPENAANDAGAACGKIAGRSRRSRREHRTCALL
                     QPRYGVK"
BASE COUNT         2105 a         2507 c         2371 g         2158 t
ORIGIN      
        1 gtcgccttgt cctgattttt gttaatccac tataattaat atgactttgc ggccgttttg
       61 ccattgcgta ataaaacgat ggggaagtga tgataaaacg tgtgtgtaac tatatcagac
      121 ggcattgttt ttctgtttga cggcctcaat ccaaaatttt gccgacgatt tcgcccacgt
      181 ctttcgacaa tccttcctgc gcccgaatgc gctgcaatgc ttgtttcacc aagtttttgc
      241 ggtgcggctc gagcttgttg cagaggttga acgcctgcac caaacgggcg gcgacctgcg
      301 ggttgaagcg gtcgatttcg atgactttgt cggcgatgaa gcggtagccg ctgccgtctt
      361 ctgcgtggaa atgcgggacg ttgcggctga agctgccgat gagcgaacgg gctttgttgg
      421 ggttttcgag gctgaatttc ggatgctgca aggcggtttg aacctgttgc agggtgtcgc
      481 tgcggcggct tgagccgata agggcgaaat atttgtccat caccagcgcg tcgtctgaaa
      541 acttgtcggc aaactgcgcc agcaggcggt tgcgcgtatc gctttcgttg ccgttgacgg
      601 cggacaggat gccccattcg tgggtcatgt tttgcgccat ttcgccgtat ttttcggcaa
      661 cggtttcgat gtgcgcgggg tcggcgcgca ggacgaaggc gcggcagacg ttgcgcagcg
      721 tgcgccagcc ggcagcttcg gggctgtact cgtagctttg gttttcctgc ttcgccgcct
      781 gacggttcaa ttcgtgccat ttcggcagga agcggacggc aagcgtgtcc aacaaggctt
      841 cgcgcgcctg atggtagcgc agcgggtcga tgttttccgc gccgtcccac agctcggctt
      901 cagacggcac gcccaaaagc agggctttga aggcgttgtc taagaggtcg tctgaaatga
      961 ctttttcgac ggcggcaagc agtttttcgt gtttcggcag ttcaataccg tctgaaagtg
     1021 cggcaaggtt ggcggcgacg gcacggcggt agagcgtttg tgcggcttcc cagcgcgtga
     1081 aggcgtcgct gtcatgggcg agcagaagca gcaggtcgtc gtcgctgtac ggatagttca
     1141 gatgcaccgg cgcgctgaac ccgcgcagca gcgagggaac gacggcttcg gttacgcttt
     1201 cgaactggaa ggtctgttcg gcttcggtca gcagtaacac ggcttcggtt gcgcgtttgc
     1261 cctgataatc gaatgccacc gcttcgccgt tgcggttcag cagcccgact ttgacgggaa
     1321 tcatcatcgg ctgcttgtcc gccatatcgg gcgtgggcgg cacggtttgt ttgatggtta
     1381 actcgaaact attgtttttc agacgacctt ccgcttccaa gacgggcgta cccgcctggc
     1441 tgtaccacaa ggcgaactgg tcgagattga tgccgttcgc gtccgccatc gccgcgcgga
     1501 aatcgtcgca ggtcacggcc tgcccgtcgt gtcgttggaa atagagcttc atgccttttt
     1561 ggaagccctc ttcgccgagc aaggtgtgat acatccgcac cacttccgcg cctttttcat
     1621 aaacggtcat ggtgtagaaa ttgttcatct cctcatagct ggcggggcgc accggatggg
     1681 cggtcgggcc tgcgtcttcg gggaactggt gctggcgcag caggcggatg ttctcgatgc
     1741 ggcgcacggc gcggctggcg cggtcgccgg aaaattcttg gtcgcggaac acggtcaacc
     1801 cttctttcag cgaaagctgg aaccaatcgc ggcaggtaac gcggttgcct gtccagttgt
     1861 ggaaatactc gtgtccgacc acggattcga tgccttcaaa atcggtatcg gtggcggtac
     1921 ggctgtcggc aaggacgaac ttggtattaa aaatgttcag ccccttgttt tccatcgcac
     1981 ccatattgaa atcgcccacg gcgacgacca tgaaaatatc caagtcgtat tccaaaccga
     2041 agcgcgtttc gtcccacttc atcgcgtttt tcaaggattc cacggcaaag ccgaccttag
     2101 gcttgtccgc ctcggcagtg taaaactcga ttttgacgtt tctgccgctc atggtggtga
     2161 aatagtcttc cgtgaccgcc aaatcgcccg cgaccaaagc aaacagataa ctcggtttgg
     2221 caaacgggtc ttcccatttc acccaatggc ggccgtctga atactcgccg ccgtcgattt
     2281 tgttgccgtt ggagagcaaa acgggatagc gttttttgtc cgcgacgatg gtggtcgtga
     2341 acttggacat gacatccgga cggtcgatat agaacgtgat tttgcggaag ccctccggct
     2401 cgcactgggt aaacaggtta ccggcggacg catacagccc catcagcgat ttgttttccg
     2461 ccggcaggat ttcggtttcc acttcgacgg tgaagcgttc ggacggcacg tctgcaatcg
     2521 tcagcgtctc gccttccaac atataatccg ccgccgcgcc gttgattttg acggacaaga
     2581 gtttcgccga accgtccaat accagcggct cccctaccct ctgcggctca accgtcaaac
     2641 gcgacttcac gacggtttgc ggttcggcaa tatcgaaatg caggtcggtt tcgagaatgc
     2701 ggtaggcagg cgtttggtaa tctttcagat aacggacggt tttgctcatt tttttctttc
     2761 aatattgttt ggtttgactg gaaaaggctt cagacggcac ggatacagct tttaaagcgg
     2821 attaacaaaa atcaggacaa ggcgacgaag ccgcagacag tactgatagt acgggctgta
     2881 ccggtttgaa tttaatccac catatgccgt ctgaaccgaa acggcggcac aagcgtaccg
     2941 ccttcggaca gcagattttc tatttccacg cttggacaaa ttctgcccaa tgcggtttgt
     3001 cttctgtttg ggcggaaaga tagtttctga tccgcttgat ttccatttcg tattcgtccg
     3061 cgtcgaatct gccgctgacc agacaaaaac gcagatacat caaatacgta ttcacggcat
     3121 cggtttcgca ataattgcgg atttctttca gcctgcccgc gtggaacgca tcccacacct
     3181 tgctgccgtc catacccagc ttgcccggaa aaccgcacag tttcgccata tcgtccagcg
     3241 gcacgtttgc cctcggctgg taaagcgcga gcaaatccat caaatcgcag tggcgttggt
     3301 gataacggct gatgtagttg ttccacttga aatcgcggct gtcgccgaaa tcgccgtcgc
     3361 ccatatccca atagcgcgcg gcgttaatgc cgtatatcag ggagcggtaa tgcagaaccg
     3421 gcaggtcgaa accgccgccg ttccaactga ccagttgcgg cgtatgtttt tcaatcaact
     3481 cgaaaaattt ggcaatcaca acttcttcgc catcgtccat ctcgccgatt gtaccgacat
     3541 ggactttatc ctgcccccaa cgcatgcagc acgaaatcgc cacaatctga tgaagatgat
     3601 gctgcataaa atccccaccc gtctgagcac ggcgtttttg ctgggcaaac agcaccactt
     3661 catcgtcggg cagcgaggac ggcagctcgt acaatgttcg gataccctgc acatcgggta
     3721 cggtttcaat atcgaaagcc aaaatcgtgg tcatgacagc accttgtatt taaaacagac
     3781 ttgcgcctat tgtgtcatta aaaggcggat aaaaaaagag gcaacccccc acaggattgc
     3841 cccaatacct caaatcagag atttacgctt cacaaacaat acaggctttc gcctgcggct
     3901 ttgcccgcgt agctcaactc tacgccggca aacttttgtt tcaccgtttc cgatgaaacc
     3961 ccgaccaatc gcaagattga ccggaaaatc ctttcagacg gcatttcctg cctgttgtgt
     4021 aattccatgt agcgaaatgt acgccatttt ctacgctttg ccaagcattt tttacaatat
     4081 aaatgccaaa acattaattt tataaaattg ctgaaaatat taaatatatg aatttttatt
     4141 ttaaatattt taataaatat aaatttaatt ttgatttata tttaaattta agcataaaat
     4201 gttaaatatt aaaggcaata tgaaaggcat atattaaata tttatttata acgctatgtt
     4261 tttaaagaaa attaatttta atatattaac tagattgtct gcagatattc atgggtttgc
     4321 ggtatttctt ccaaaacctg cttcgaattt tccgaccaag tcttaaaaat attgtttttt
     4381 gagataatta aatagcagcg attatcaaat gaaatctgtt catataatct gccatttcgc
     4441 atttaaaaaa acaaacagga gtttcgactc gaaacgcctg atatgttttg taattttacg
     4501 tagtcagtaa aaatcggggc tgccttccgg acgggttttg aaacgcttgt gcagccaaaa
     4561 atactgctcg ggatgttcgc gcacgcgttc ctcgataaaa cggttcatgc gctgcgcgtc
     4621 ggcctgcgca tcttcactcg gaaaggattc ccaagccggg tagaaatgca atgtaaccgt
     4681 attgtccgcc tcgcggacgg ggatggcggg tatcactttt gcatttgcaa gcgcggcaat
     4741 gcggctcaag ccggtaatcg ttgccgtctg aataccgaaa aaatccacaa aaaccgaatc
     4801 gttgcgtccg aaatcctgat cgggcagata cagaaacggc gcgctgcttt tgcggaactg
     4861 tttgacgagg gcgcgcagcc cttcggtgcg cccgataagg aaaacgttgt gatagcggtt
     4921 gcggcctttc aaaatctgtt cgtccaatat cttgtttttt tggtgggaat acatactgat
     4981 cagcggaaca tcctgattaa gtgcgtacac cgccatctcg aacgcggtaa agtgcggata
     5041 caggatgatg actttttccc ccgccgccag cgcgtcgtcc aaataatgct tattgcggta
     5101 gcgcaccagc gatttcaaac gtccggcagg cgcgtaccaa tataaaccgt attccaacat
     5161 cagtttcgcc atgtgcctga aatgctgttt caacacggtt ttacgctttt cctcactcca
     5221 ttcgggaaaa catttcacca aattgatttc gccgatacgg cggcgcggtt tgaccagaag
     5281 gtaggcaagc aaacccgtca ggtcggcaat cttgtgcagc agcgcaaacg gcagaaactg
     5341 caaaacatac agtacaaaaa atataaattt catctcgata cacattttct tttcagacgg
     5401 caaaatacaa atgccgtctg aaactattga aaccttccgc gcttgacctg catccccgac
     5461 gggttgagcc gggacgcaag cccgtggttg cgtaaggcgt gggtcagcgc gacggcaaga
     5521 ccgtccgccg catccgcctg cggcgttccc gaaagcccca gcatctgcac caccatatgc
     5581 tgcacctgtt cttttgccgc cttgcctttg ccgactaccg cctgtttgac ctgcaaggcc
     5641 gtgtattccg aaacgggcag cttatggctg accaatgccg ccaatgccgc gccccgcgcc
     5701 tgaccgagca tcagcgtcga tgccggattg acgttgacga acacctgttc cactgccgcc
     5761 tgttgaggct tgtaaacggt aacgacttcg ccgatgtgcc ggacgatgac ggcaatcctg
     5821 tctgccagag gcgcatcggc aggcgttttg atgcagccgg aggcgacgta aaaatgatcg
     5881 cgccccctga catcgatgat gccgaaaccc gttacgcggc tgcccgggtc gatacctaag
     5941 atacggacgg ttgccgacat attcacagca aaccgtgttg aatcagtttt ttacgcaaag
     6001 tattgcggtt cagtcccaac atgacggagg ctttggactg gttgccgccg cattgctcca
     6061 tcacgcacac cagcagcggc ttttccacct gatgcaatac catatcgtac acgccgcaag
     6121 gttcggtacc gttcaggtct ttgaaatatt gttccaaatt ttgtctgata cattgggaaa
     6181 tatcgggaag ggtatggggc atgattgcac tttcaaagga taatcaagtg ttcagaaggc
     6241 atttgtgcgg tagccgcacg cccaacggtc ggtttttccg gcaagtcttt caagataacc
     6301 tgcaagcatg tcgtattgcg ccgccgcact gtccaagcgg ttgatttcac gccgcgcctg
     6361 ttcgccgtcg ggcatttcgc cgatgtacca acctatgtgt ttgcgtgcga tgcgtacgcc
     6421 tgcactatcg ccgtaaaacg cgtgtatggc gcggatgtgg ttcaaaatag cggcggcgca
     6481 ttctgccaaa ctcaaggcag gcggcaaaac accgtgttcg gcataatgtt tcaaatcgcg
     6541 gaagaaccac ggcctgcctt gcgcgccgcg ccctatcata atgccgtcgg cggcggtttg
     6601 tttgaggacg gcttgggctt tttgcggcga agtaatgtcg ccgttgaccc agaccgggat
     6661 gttcagacgg catttggttt cggcgatgag ttcgtaacgc gcttcgcctt tgtacatttg
     6721 cgtgcgcgtg cgtccgtgga cggcaagggc ggcgatgccg caatcttcgg cgattttggc
     6781 gatgacgggc aggttttgat ggtcgtcgtg ccaacccaaa cgggttttga gggtaacggg
     6841 tacgcctgcc gcacgaacga cggcttccaa aatggcggca accagcggct cgttctgcat
     6901 cagcgcgcta ccggcttgga cattgcagac ttttttagcg ggacagccca tgttgatgtc
     6961 gataagctgc gccccaaggc tgacgttgta acgcgcggca tccgccatct gctgcggatc
     7021 gctgccggca atctgcacgg caacgatgcc gccttcatcg gcaaaatcgc tgcggtgcag
     7081 ggtctttttg gtatttctaa gtgtcgggtc gctggtcagc atttcgcaca ccgcccaacc
     7141 cgcgccgaaa tcgcggcaga ggcggcggaa gggtttgtcg gtaatgcccg ccatcggtgc
     7201 aagtgcgatg gggttgtcga taaaatagcc gccgatgtgc ataatggatc cgcgtttcaa
     7261 aaaagtgcgc cattgtacat tttttaagca ggatttccaa tctccgaacg cgcccgcgat
     7321 tgggtcggac accgttttat ggcataatcc gcacacagat tccctgcccc gccactcaca
     7381 ggagggcagt ttatagtgga ttaacaaaaa ccggtacggc gttgcctcgc cttagctcaa
     7441 agagaacgat tctctaaggt gctgaagcac caagtgaatc ggtttcgtgc tatttgtact
     7501 gtctgcggct cgccgccttg tcctgatttt tgttaatcca ctatatttcc ccgtcctatc
     7561 ggtttcccgt ttcagacgac ataaggtctg aaagaaagac tacaattatg agtaatccat
     7621 tttcctcttt aggtttgggt acggaactcg tttccgcact gaccgcgcaa ggttacgaaa
     7681 acccgacgcc catccaagcc gccgccattc ccaaagcact cgccggtcat gatttactag
     7741 ccgccgcgca aaccggcacg ggcaaaaccg ccgcctttat gctgccctcg ctcgaacgcc
     7801 tcaagcgtta cgccaccgcc agcacctcgc ccgcgatgca ccccgtgcgt atgctcgtcc
     7861 tcacccccac gcgcgaactt gccgaccaaa tcgaccaaaa cgtgcagggc tacatcaaaa
     7921 acctgccgct gcgccacacc gtcttgttcg gcggtatgaa tatggacaaa cagaccgccg
     7981 acctgcgtgc cggctgcgaa atcgtcgtcg ccaccgtcgg acggctgctc gaccacgtga
     8041 aacagaaaaa catccatttg aacaaagtcg aaatcgtcgt tttggacgaa gccgaccgta
     8101 tgctggatat gggttttatc gacgacatcc gcaaaatcat gcagatgctg ccccgccaac
     8161 gccaaaccct gctcttttcc gccaccttct ccgccccgat acgcaaactg gcgcaagact
     8221 tcatgaacgc gcccgaaacc gtcgaagtcg ccgcgcaaaa caccaccaac gccaacgtcg
     8281 agcagcacat catcgccgtc gataccattc agaagcgcaa cctgctcgaa cggctgattg
     8341 tcgatttgca tatgaaccag gtcatcgtgt tctgcaaaac caaacaaagc gtcgaccgcg
     8401 taacgcgcga actggtgcgc cgcaacctgt ccgcacaggc gatacacggc gaccgttccc
     8461 aacaaagccg gctcgaaaca ctcaacgcct tcaaagacgg caacctgcgc gtcctcgtcg
     8521 ccaccgatat cgccgcgcgg gggctggata ttgccgaact acccttcgtc atcaattacg
     8581 aaatgcccgc ccagcccgaa gactacgtcc accgcatcgg gcgcacgggg cgcgcgggcg
     8641 cggacggcgt ggcgatttcc ctgatggacg aatccgaaca gaaaatgttt gaatccatta
     8701 aagagctgac cggcaacaag ctgctcatcg agcgcatcga gggcttcgag ccgcaatggt
     8761 gggaacaggg cggcgcaaaa ccggaaaaac ccgaaatgcg cgaaccaaga caacgcaacc
     8821 gctacgaatc cgccaaagcg caacgcgaaa aaaacacccg gccggaaaat gcggcaaacg
     8881 atgcgggcgc ggcttgcgga aaaattgccg gacgcagccg ccgaagccgc cgggaacacc
     8941 ggacgtgcgc cctgctccaa ccgcgttacg gcgtaaaata accctgaaaa tcaaatgccg
     9001 tctgaacatt tcccgtttca gacggcattt ttcaaaccag actaacgcat tgggcgcaac
     9061 cgcccgcaca ggataaattt ctgccgcaaa cagtttcaga cggcatttgc cgcctgtaca
     9121 atatagtgga ttaacaaaaa t
//
LOCUS       DAXIDM010000076         9101 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000076 DAXIDM010000000
VERSION     DAXIDM010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9101
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.076"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(47..1303)
                     /locus_tag="ACFOAE_001510"
     CDS             complement(47..1303)
                     /locus_tag="ACFOAE_001510"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HFC6884975.1"
                     /translation="MNAAQLDHTAKVLAEMLTFKQPSDAVLSAYFREHKKLGRQDRHE
                     IAETAFAALRHYQKISTALRRPHAQPRKAALAALVLGRSTNISQIKDLLDEEEIEFLG
                     NLKARKTEFSDGLNTAAELPQWLVEQLQQHWREEEILAFGRSINQAAPLDIRVNTLKG
                     KRDKVLPLLQAESADAEATPYSPWGIRLKNKIALNKHELFLDGTLEVQDEGSQLLALL
                     VGAKRGEIIVDFCAGAGGKTLAIGAQMANKGRIYAFDIAEKRLANLKPRMTRAGLTNV
                     HPERISSEHDSRIARLAGKADRVLVDAPCSGLGTLRRNPDLKYRQSAETVAKLLEQQH
                     SILDAASKLVKPQGRLVYATCSILPEENELQVERFLSEHPEFEPVNCAELLQNLKIDL
                     DTGKYLRLDSAKHQTDGFFAAVLQRK"
     gene            complement(1651..1992)
                     /locus_tag="ACFOAE_001511"
     CDS             complement(1651..1992)
                     /locus_tag="ACFOAE_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884976.1"
                     /translation="MKNNVKNWTTKEVKQSLDKFNNILIKNTFLLQYLKKEFSASSAY
                     CLSMLPEEEDIYEILVNGNIIIDLEFNKHTNETVVINVTDVDEYLKTLTNESGRVFFT
                     LAKEIGKQKNI"
     gene            complement(2196..3053)
                     /locus_tag="ACFOAE_001512"
     CDS             complement(2196..3053)
                     /locus_tag="ACFOAE_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1853 family protein"
                     /protein_id="HFC6884977.1"
                     /translation="MNYALDALWWKLTSQPVRDLASLLTAPPLWQSGCELGVRELLGE
                     RGFRYLLALDADPAPLTEHLTRRAPFGHRLGIYAEELLAFWFANAPHAELLAHNLTVS
                     GSDGNTQGAADFVVRLNGKPYHIELTCKYYGGGTGRLEDMRGLDPKDTLLGKAAKLTA
                     QLGLPHTSDGIRTLRQHGLPLDVKPVSIVRGIGFFPHGFHAFEPPLNPYGWRGIYIQY
                     WAEYGFERQEARYHLLDRMAYLAPARVAETEALNETEIRRIDQGLIAVLELRPDGFWH
                     EIERIMKAV"
     gene            complement(3114..3929)
                     /locus_tag="ACFOAE_001513"
     CDS             complement(3114..3929)
                     /locus_tag="ACFOAE_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HFC6884978.1"
                     /translation="MTTLKPALPAYLDNIRIILTRTSHPANIGSAARAMKTMGLHKLT
                     IVAPNLMATPMTENPPVFDPEHPQSFKLPEESFILASGAADVLENATIAASLDEALAD
                     TTIACALTSRRREITAPLQTPRDLVSELLQTANRGEKVALVFGNETFGLSIEEVQACN
                     RLMTINGNPDYFSLNLAQAVQIVCYEIFSQTGSPMTHLQQEDHAATHEQIKGMVAHME
                     SVMNDIGFFNRRNGERLMRRMQSLFGRANTQTEDINILRGFFNTVSHRIHKKD"
     gene            3993..4163
                     /locus_tag="ACFOAE_001514"
     CDS             3993..4163
                     /locus_tag="ACFOAE_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002254490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884979.1"
                     /translation="MPSEMFFNNVGNLTLRLKQTRVGRYFTRFGRIYPNQINSDFAAP
                     KDCASEPAVCHP"
     gene            4173..4958
                     /locus_tag="ACFOAE_001515"
     CDS             4173..4958
                     /locus_tag="ACFOAE_001515"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008934 - inositol monophosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006020 - inositol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046855 - obsolete inositol phosphate
                     dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFC6884980.1"
                     /translation="MNPFLNTAFKAARRAGQMMIRAAGNLDAVKTDSKAFNDFVSDVD
                     RNSEIILVEALKEAYPHHKITCEESGSHGKAAAEYEWIIDPLDGTTNFLHGHPQYAIS
                     MALLHKGVLQEALVYAPERNDVYMASRGKGALLNDRRIRVSNRIELNRCLIGTGFPVV
                     DQSMMDKYLAILKDFLAKTAGGRREGAASLDLCAVATGRFDGFFEFNLKPWDIAAGAL
                     IVQEAGGIVTDMTGEDGWLESGDIVAANPKVLAQMLKIISAHV"
     gene            5139..7333
                     /locus_tag="ACFOAE_001516"
                     /pseudo
     CDS             5139..7333
                     /locus_tag="ACFOAE_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009173530.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0015343 - siderophore-iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
     gene            7457..9007
                     /locus_tag="ACFOAE_001517"
     CDS             7457..9007
                     /locus_tag="ACFOAE_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HFC6884981.1"
                     /translation="MKKPLISVAAALLGVALGTPYYLGVKAEESLTQQQKILQETGFL
                     TVESHQYERGWFTSMETTVIRLKPELLNNARKYLPDNLKTVLEQPVTLVNHITHGPFA
                     GGFGTQAHIETEFKYAPETEKVLERFFGKQAPVSLANTVYFNGSGKMEVSVPAFDYEE
                     LSGIRLHWEGLTGKTVYQKGFKSYRNSYDAPLFKIKLADKGDAAFEKAHFDSETSDGI
                     NPLALGSSNLTLEKFSLEWKEGVDYNVKLNELVNLVTDLQIGAFINPNGSIAPSKIEV
                     GKLAFSTKTGESGSFINSEGQFRFDTLVYGNEKYGPLDIHIAAEHLDASALTVLKRKF
                     AQISAKKMTEEQIRNDLIAAVKGEASGLFTNNPVLDIKTFRFTQPSGKIDVGGKIMFK
                     DMKKEDLNQLGLMLKKTEADIRMSIPQKMLEDLAVSQAGNIFSVNAEDEAEGRASLDD
                     INETLRLMVDSTVQSMAREKYLTLNGDQIDTAISLKNNQLKLNGKTLQNEPEPDFDEG
                     GMVSEPQQ"
BASE COUNT         2285 a         2155 c         2396 g         2265 t
ORIGIN      
        1 cataaaattt tagtaaccta tgttattgca aaggtctcaa accggtttat ttgcgttgca
       61 atacggcggc gaagaagccg tcggtttggt gctttgccga atcgaggcgc aggtattttc
      121 cggtatccaa atcaatcttc aggttttgca gcagttcggc gcagttgacg ggttcaaatt
      181 cgggatgttc ggacaggaaa cgttcgactt gcagctcgtt ttcttcgggc aggatgctgc
      241 aagtggcgta aaccaagcgg ccttgcggtt ttaccagttt ggaggcggca tcgaggatgc
      301 tgtgttgctg ttccaaaagt ttggcgacgg tttcggcgga ttggcggtat ttgagatcgg
      361 gattacggcg taaagtaccc aaaccggagc agggcgcatc cactaaaacg cggtcggctt
      421 tgcctgccag tcgtgcgata cggctatcat gttcgctgct gatgcgttcg gggtggacgt
      481 tggtcagtcc ggcgcgggtc atgcgcggtt tgaggttggc aaggcgtttt tcggcgatgt
      541 cgaaggcgta gattctgcct ttgttcgcca tttgcgcgcc gatggcgagg gttttgccgc
      601 ctgcgccggc acagaaatcg acaatgattt cgccgcgttt tgcgcccacc aataaagcaa
      661 gcagctggct gccttcgtct tggacttcca gcgtaccgtc caaaaacagc tcgtgtttgt
      721 taagcgcgat tttgtttttc aggcggatgc cccaaggcga ataaggcgtt gcctctgcat
      781 cggcactttc ggcttgcaac aatggcagca ctttatcgcg tttgcctttc aaggtattga
      841 cgcgtatatc gagcggcgca gcttggttga tgctgcggcc gaaggcgagg atttcttctt
      901 cgcgccaatg ctgctgcagc tgttctacca gccattgcgg caattctgcg gcggtattca
      961 ggccgtctga aaactcggtt ttacgggctt tcaaattgcc gagaaactct atttcttctt
     1021 catcaagcag gtctttgatt tggctgatgt tggtgcttct gccgagaacc agtgcggcga
     1081 gtgcggcttt gcgcggctgc gcgtgcggac ggcgcagggc ggtactgatt ttttgatagt
     1141 ggcgcagcgc ggcaaaggcg gtttcggcga tttcgtggcg gtcttggcgg ccgagctttt
     1201 tgtgttcgcg gaaataggcg gagaggacgg catcggaagg ctgtttgaaa gtcagcattt
     1261 cagccaaaac tttggcggta tggtcgagtt gtgcggcgtt cataatgtaa tgggttctct
     1321 tactgtgggt tattcataat caatctaacg tccttaaaat aacaatagca tctttatcat
     1381 tacttagtat tctatccgca ataagaaaga tgtgttaaaa gtgcgcaatc gggatttgtc
     1441 taaatttctc cgttaactac aaaggcagcc tgaaaaaagt tctattttca ggtcgcttga
     1501 acagcatccg atataatcac atcagcgatt tcattttgta atcactccct aaaacatgag
     1561 gaaaaaaaca aaatttattt tcttcgttca gtatatctat cctaaatatg ccatcactcc
     1621 attgagtttt taatttgtat ttcgctcttg ttaaatgttt ttctgtttgc cgatttcttt
     1681 tgctaatgta aaaaatactc taccactctc attggttaaa gttttcaagt attcatcaac
     1741 atcagtaaca ttaataacaa ctgtttcatt tgtatgttta ttaaattcta aatcaataat
     1801 aatattccca ttaaccaata tttcatatat atcttcttct tcagggagca tagacaaaca
     1861 ataagcactt gaagctgaaa actctttttt cagatactga agaagaaaag tatttttaat
     1921 taaaatatta ttaaatttat ctaatgattg cttgacttct ttagttgtcc aatttttaac
     1981 attattcttc attgtattct acctggggtc gtagttatta aattaccata cttatttgtt
     2041 tggatcgtca taatattagt tggcatgttg ttgttatatt tatcatatcc aatatcctta
     2101 ttaactcgga tgactctttc ataaattgta tgggaaatga gatttccatc actaagcctc
     2161 tcaatagata tacgcgttaa tgttgggaaa gggtttcaga cggccttcat aatgcgttcg
     2221 atttcgtgcc aaaagccgtc ggggcgcaat tccaaaacag caatcaagcc ttggtcgata
     2281 cggcggattt cggtttcgtt caatgcttcg gtttcggcaa cacgcgcagg cgcgagatag
     2341 gccatacggt cgagcaggtg gtagcgtgct tcttggcgtt caaacccata ttccgcccaa
     2401 tattgaatat agataccgcg ccagccgtat ggattaagcg gcggctcaaa agcatggaaa
     2461 ccgtgtggaa aaaatccgat gccgcgcacg atggaaacgg gttttacgtc aagcggcaga
     2521 ccgtgttgcc gcaaggttcg gatgccgtct gaagtgtgcg gcagaccgag ttgggcggtc
     2581 agtttggcgg cttttcccaa cagcgtgtct ttggggtcga gtccgcgcat gtcttcgagc
     2641 ctgcccgtgc cgccgccgta atatttgcag gtcagctcga tatggtaggg tttgccgtta
     2701 agccttacca caaaatccgc cgcgccttgc gtattgccgt ccgaaccgga aaccgtgagg
     2761 ttgtgcgcga gcagttcggc gtgtggcgcg ttggcaaacc aaaatgccag cagttcttcg
     2821 gcgtaaatgc cgaggcggtg tccgaacggg gcgcgtcggg tgaggtgttc cgtcagcggc
     2881 gcgggatcgg catccaatgc caaaagatag cggaaaccgc gttcccccaa tagttcgcgc
     2941 acgcccaatt cgcaaccgct ttgccacaaa ggcggcgcag tcagcagcga ggcgaggtcg
     3001 cggacgggtt ggctggtgag cttccaccat aatgcgtcta gggcgtaatt catgcttatc
     3061 cgaatatcag tcatgccgtc tgaaaagctg gaaatgtttt cagacggcct taatcagtct
     3121 tttttatgga tacgatggct gacggtattg aaaaaaccgc gcaggatatt gatgtcttcg
     3181 gtttgcgtgt tggcgcgtcc gaacaggctc tgcatacggc gcatcagacg ctcgccgttg
     3241 cggcggttga aaaagccgat gtcgttcatc acgctttcca tgtgggcgac catgcctttg
     3301 atttgctcgt gggtcgcagc gtggtcttct tgttgaagat gggtcatggg cgaaccggtt
     3361 tggctgaaga tttcgtagca cacgatctgc acggcttggg cgaggttgag cgagaaatag
     3421 tcgggattgc cgttgatggt catcagtcgg ttgcaggctt ggacttcttc gatgctcaag
     3481 ccgaaagtct cgttgccgaa aaccagtgcc actttctcgc ctcggtttgc ggtctgcagt
     3541 aattcggata ccaaatcgcg cggggtttgc agcggcgcag taatttcgcg gcggcggctg
     3601 gtcagggcgc aggcgatggt ggtgtcggca agggcttcgt ccaaagaagc ggcaatggtg
     3661 gcattttcca aaacgtctgc cgcgccggaa gcgaggatga agctttcttc cggtaattta
     3721 aacgattgag gatgctccgg gtcaaacacg ggcgggtttt ccgtcatcgg cgttgccatc
     3781 agatttgggg cgacgatggt cagtttgtgc agacccattg ttttcatcgc gcgcgcggca
     3841 gagccgatgt tggcgggatg gctggtgcgc gtgaggatga tgcggatgtt gtccagataa
     3901 gcgggcaggg cgggtttgag agtagtcatg ttcggttttc ggtcggaatg gaatagggta
     3961 taatgcgccg tctttttcgt tcggacggtc aaatgccgtc tgaaatgttc tttaacaacg
     4021 tcggaaattt aacgttgcgc ctgaagcaga cacgcgtcgg gcggtatttt acccgatttg
     4081 gcaggattta ccccaaccaa ataaactccg attttgccgc tccgaaggac tgcgcgtccg
     4141 aaccggcggt atgccaccct taaggaaatc tgatgaatcc gtttttgaat acagccttta
     4201 aagccgcccg ccgtgccggt cagatgatga tacgcgccgc gggcaatctc gatgccgtca
     4261 aaaccgacag caaagcattc aacgattttg tttccgatgt tgaccgcaat tccgaaatca
     4321 tcctggttga ggctttgaaa gaagcctatc cgcaccacaa aatcacttgc gaagaaagcg
     4381 gctcccacgg taaagccgca gccgaatacg aatggattat cgatccgctc gacggcacga
     4441 ccaacttcct tcacggccat ccccaatacg ccatctctat ggcactcctg cacaaaggcg
     4501 tgttgcaaga agctttggtg tacgcccccg aacgcaacga cgtttacatg gcttcgcgcg
     4561 gcaaaggcgc gttgctcaat gaccgccgca tccgcgtttc caaccgcatc gaattgaacc
     4621 gctgcctgat cggtaccggc tttcctgttg tcgatcaaag catgatggac aagtatctgg
     4681 cgattttgaa agatttcttg gcaaaaaccg ccggcggccg tcgtgaaggc gcggcttctt
     4741 tggatttgtg tgctgtggcg actggtcgtt ttgacggctt tttcgagttc aacctcaaac
     4801 cttgggatat tgccgcaggc gcattgattg ttcaggaagc gggcggtatc gtaaccgata
     4861 tgacgggtga agacggctgg ctggaaagcg gcgatattgt ggctgccaat cccaaagtgc
     4921 tggcgcaaat gttgaaaatc atttccgcac acgtttaaat ttcagcccgc tcccgggaat
     4981 gcgggaaaac gggcgggtat gccgtctgaa gtatcgcgcc gatatttcag acggtatttt
     5041 tattggtaac aagagtggga aggtggaaac ggctaaatgt tccaaactgc cgaggatgga
     5101 aactaaacgg agaaccctgt gcaatttgtt tatagtggat taacaaaaac cagtacggtg
     5161 ttgcctcgcc ttagctcaaa gagaacgatt ctctaaggtg ctgaagcacc aagtgaatgg
     5221 gcaaagccaa cgcctttacc gcaccgatta ccgtcgtcaa ttacgacgaa caagccctca
     5281 ataacaccga agcgcgtact ttggtggatg ccgtagcgaa aaaagatgct tccgtttggc
     5341 agttcggcgg cgaaagcaac acgctgaccg gactgtattt cagaggttat cagcttgatg
     5401 cgcgccaatt cagcgtcaac ggtttggcag gtatgtacgg cacgcaaggc acggcaagcg
     5461 tgcaagttgg atcggcacaa ctgattaaag gcgcatccac tgccgtaaac ggcatggacc
     5521 ctgaaggtgc ggtatccggt tccgtcaata tcgaaaccaa aaaagccgcc gatgaaggca
     5581 accgcaaaat cggtttgggc cggtttagca acaaccgcgc ccaaggtacg ttcgacttgg
     5641 gtcaacgctt cggcgaaaac aaagcattcg gcgtacgcgc caacggcaaa ctgcgccacg
     5701 gcgacactcc gcgccacggt tacagcgaag acaacaaaga atttgcggta aatgccgact
     5761 atcgcggcga aacactgcgc gtagcgttcg attccatcta cgcaaaacca acggcggtcg
     5821 cgcgcgtatg caggacattc aaaacgccgg cggacgcttg tttggcgcgc ccgatggtaa
     5881 aaccaacctg ctgccttctt ggaactggca aaataccgcc ggccaaacca atatgcttac
     5941 gtttgaatgg gatgcgtttg ataatgcaca gattacaggc ggtatcggct acaacaaggc
     6001 acgctattac ggcacgctga tttccccgac cgtatgtttg aatgctacca gcacttgtac
     6061 cgatatgcaa aacacaaacg ccagcggcaa agtaacggca cgcaactatg actacaatac
     6121 cggtactgcg cgcctgaccg accaatattt ccgcacattg agtatgaacc tgaccgcacg
     6181 cggcgaattt gaaaccagcc cggtaacaca taactggagt acggctttcg accgcgttat
     6241 ccgccagcgg aaaaccattc gcggaacggc agccggcgct ggcaaggtag aagtgaaggc
     6301 aaacgaaaat attgcgaatc aattggcatc gttcaaagcc gactatccca attcttggga
     6361 gaactctgcc aacttggatg ccaatatcaa agtcaacagc ctggctttgt ccgacacctt
     6421 gggcttcgtg gataacaaat accgcctgac tttgggcgga cgtttccaag cggttgaata
     6481 caccaataag aaaaaatcac agagcggcga tgccaaacgc ttcagcccga tgctgatggc
     6541 ggcgtgggtg ccgcaacctg atttggttgt gtacggcaac tatatggaag acttggagcc
     6601 tgccgatatc aaaaccgatg attccggcga aacgacaatg gcgaaaccgc gtgtcagccg
     6661 tcagtttgaa gtgggcgtgc gtaaaaactg gggcaatttc gtaaccacgt taaacgcgtt
     6721 ccaaatcaaa cgcccgggct actggcgcgg tcatacaact accaagacaa caaaaggggt
     6781 aacaacaacg ctgacctatg gcaacaattc cgatttcgcc cgctataagg cgcaaggcgg
     6841 cgcggccggc gacgagcaag gtatggaacg caatcgcggt attgagttca atgcctatgc
     6901 taacctgtta aacaaaaccc tgcgtccgac tttgggcctg atgtatctgc aatcgaccgt
     6961 gaaagagtat ccaaattcac gcgatatgct ggttaacggc gtacaagtcg ccaatccgcg
     7021 cgtaattgcc aaggcaggtt tggaatggga tacaccgttt gccaaaggct tgactttaaa
     7081 cagcaatgtt tcgtatttcg gcaagtctta ccaagacacg caaaaacaat acgctttccc
     7141 gtcttacact ttggttgacg taggcgcgcg ctacaaaacc aagctcggca aaaatacgtt
     7201 gaccgtcagc agctcggtgg aaaacctgtt caacaaaaac tactggcagg tacagcgcgg
     7261 ccaatacgac cgcagcttcg ccgtcgtcgg tatgccgcgt acttactggt tgaaagcgga
     7321 attggatttc tgatttctcc gcatccggaa aatgccgtcc gaacaggttt cagacggcat
     7381 ttcttttaaa gaaatatggc gggatatgct taaataatgc tattctagcg tctttgaaac
     7441 ctgcttgttt gaagtgatga aaaaaccttt gatttcggtt gcggcagcat tgctcggcgt
     7501 tgctttgggt acaccttatt atttgggtgt caaagccgaa gaaagcctga cgcagcagca
     7561 aaaaatattg caggaaacgg gcttcttgac cgttgaatcg caccaatatg agcgcggctg
     7621 gtttacctct atggaaacga cggtcatccg tctgaaaccc gagttgctga ataatgcccg
     7681 aaaatacctg ccggataacc tgaaaacagt gttggaacag ccggttacgc tggttaacca
     7741 tatcacgcac ggcccttttg ccggcggatt tggcacgcag gcgcacattg aaaccgagtt
     7801 caaatacgcg cctgaaacgg aaaaagtttt ggaacgcttt tttgggaaac aagctccggt
     7861 ttcccttgcc aataccgttt attttaacgg cagcggtaaa atggaagtca gtgttcccgc
     7921 cttcgattat gaagagctgt cgggcatcag gctgcattgg gaaggattga cgggaaaaac
     7981 ggtttatcaa aaaggtttca aaagctaccg caacagctat gatgcgccct tgttcaaaat
     8041 caagctggca gacaaaggcg atgccgcgtt tgaaaaagcg catttcgatt cggaaacttc
     8101 agacggtatc aatccgcttg ctttgggcag cagcaatctg accttggaaa aattctccct
     8161 agaatggaaa gagggtgtcg attacaacgt caagttaaac gaactggtca atcttgttac
     8221 cgatttgcag attggcgcgt ttatcaatcc caacggcagc atcgcacctt ccaaaatcga
     8281 agtcggcaaa ctggcttttt caaccaagac cggggaatca ggctcattta tcaacagtga
     8341 agggcagttc cgttttgaca cgctggtgta cggcaatgaa aaatacggcc cgctggacat
     8401 ccatatcgcc gccgaacatc tcgatgcttc tgccttaacc gtattgaaac gtaagtttgc
     8461 acaaatttcc gccaaaaaaa tgaccgagga acaaatccgc aatgatttga ttgccgccgt
     8521 caaaggcgag gcttccggac tgttcaccaa caatcccgta ttggacatta aaacttttcg
     8581 tttcacacag ccgtcgggaa aaatcgatgt gggtggaaaa atcatgttta aagacatgaa
     8641 gaaggaagat ttgaaccaat tgggtttgat gctgaagaaa accgaagccg acatcagaat
     8701 gagtattcct caaaaaatgt tggaagactt ggcggtcagt caggcaggca atattttcag
     8761 cgtcaatgcc gaagatgagg cggaaggcag ggcaagtctt gacgacatca acgagacctt
     8821 gcgcctgatg gtggacagta cggttcagag tatggcaagg gaaaaatatc tgactttgaa
     8881 cggcgaccag attgatactg ccatttctct gaaaaacaat cagttgaaat tgaacggtaa
     8941 aacgttgcaa aacgaaccgg agccggattt tgatgaaggc ggtatggttt cagagccgca
     9001 gcagtaatgg gtcaaatgcc gtctgaaatg ttcaggcggc attttgttgt attggaaact
     9061 gccgttttca accattcctt tagataagcc gtgtcggatt c
//
LOCUS       DAXIDM010000077         9068 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000077 DAXIDM010000000
VERSION     DAXIDM010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9068
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.077"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            179..1354
                     /locus_tag="ACFOAE_001518"
     CDS             179..1354
                     /locus_tag="ACFOAE_001518"
                     /EC_number="1.13.12.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent flavin oxidoreductase"
                     /protein_id="HFC6884982.1"
                     /translation="MQNIFDPLVIRGKSLTPIVQGGMGVGVSASGLSSAVARENGIGT
                     IASVDLRHLHEDLLAESQINPSEEKYTSLNCTALDREIQKAKSASEGKGLIAVNVMKA
                     VKDHAAYVRQACESGADAVVMGAGLPLDLPEMTEGYHKYVALLPILSESRGINIVLKR
                     WMKKGILPDAIVVEHPAHAAGHLGASTVEGVNDAKFDFKRVIEETFEVFKSLGLESEK
                     IPLILAGGMANFEKVKTALKNWGASAVQIGTAFAVTEEGDAHLNFKKTLAGAETEKVV
                     EFMSVAGLPARGVRTKFLDSYIKRESKLQANAKADPRRCTQGLNCLTSCGLRDGLSKA
                     GQFCIDIQLAAAFRGEVDKGLFFRGKDPLPFGNAIRTVRETIQYLLTGSEPVATLGR"
     gene            complement(1827..2375)
                     /locus_tag="ACFOAE_001519"
     CDS             complement(1827..2375)
                     /locus_tag="ACFOAE_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FixH family protein"
                     /protein_id="HFC6884983.1"
                     /translation="MSQNTSIKPWYKHVWPWILMAGPIFVVIASVAMFFVAQQHATDL
                     VTDDYYKDGKHIDIQLHRDEEAVRRHIGVQVLISPDMNAAKVFVGGEFDGKQPLNLLL
                     MHPTRKADDQTVALKPVGSAQNGRAEYEAVFKTLSPTNHWYVRVEDAAGVWRVENKWI
                     TSQGNAVDLTPMDKLFNNAGSK"
     gene            complement(2378..3874)
                     /gene="ccoG"
                     /locus_tag="ACFOAE_001520"
     CDS             complement(2378..3874)
                     /gene="ccoG"
                     /locus_tag="ACFOAE_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003708970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c oxidase accessory protein CcoG"
                     /protein_id="HFC6884984.1"
                     /translation="MTTENQAGNPESGIGTSEQTKAAPKAKKTFDPRASVIQIHPEGE
                     RIHPKKAEGRFAKLRIAAVLATQFVFYVIPWFNWSGRQAVVFNIPERHFFIFGLSLGV
                     GDLIYLALLLMICAFGLFWWTTIAGRLWCGYSCPQTVYTEIMLWIDNLVEGDRNKRLK
                     LEKSPWNFTKIRIKATKYLLIFLVCAWTGITFAGWFVPIRQFVPDLFTGAAGGGAVFA
                     AAFYGFMTFFFAHIMREKVCLHMCPYARFQSAMFDKDTLIVSYDAERGEPRGARKKTV
                     NKEEAGLGDCINCAMCVQVCPVGIDIRNGLQYQCIGCAACIDACDEIMDKMGYPRGLI
                     RYTTESALEHEYAEKDIKKRLLRPRVAGYGAVLALVIIAFLAGLSTRKMVEVDILKDR
                     GVLVRENAKGWLENAYSLRIINKSEKEQLITASVKGFDEIALTGLPEGGIKVAPRETV
                     TLPVQVSTIPEYADKGSHPIEFTFQYRESGAPDGKPVVLEEDATFIGE"
     gene            4401..6380
                     /gene="tkt"
                     /locus_tag="ACFOAE_001521"
     CDS             4401..6380
                     /gene="tkt"
                     /locus_tag="ACFOAE_001521"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFC6884985.1"
                     /translation="MSQLANAIRFLSADAVQKANSGHPGAPMGMAEMAETLWTKFLNH
                     NPANPKFYNRDRFVLSNGHASMLLYSLLHLTGYNLSIEDLKNFRQLHSKTPGHPEYGY
                     TDGVETTTGPLGQGIANAVGMALAEKILAAEFNKDGLNIVDHYTYVFMGDGCLMEGVS
                     HEACSLAGTLGLGKLIVLYDDNNISIDGKVDGWFTENIPQRFESYGWHVVPNVNGHDT
                     AAIQAAIEAARAETGKPSIICCKTLIGKGSANKEGSHKTHGAPLGADEIEATRKHLGW
                     TYPAFEIPQEIYDAWNAKEQGAKLEADWNELFAQYQAKYPAEAAEFVRRMDKKLPENF
                     DEYVQTALKEVCAKAETIATRKASQNSIEILAKELPELVGGSADLTPSNLTDWSNSVS
                     VTRDKGGNYIHYGVREFGMGAIMNGLALHGGIKPFGATFLMFSEYERNALRMAALMKI
                     NPVFVFTHDSIGLGEDGPTHQPIEQTATLRLIPNMDVWRPCDTAESLVAWAEAAKAED
                     HPSCLIFSRQNLKFQARNEQQLNDIKRGGYVISEAQGNAQAVIIATGSEVELALEAQK
                     ALAAQNIAVRVVSMPSTNIFDRQDAAYKAAILPEGLPRVAVEAGHADGWYKYVGLNGA
                     VVGINRFGESAPADLLFKAFGFTVDNVVDTVKSVL"
     gene            6521..7909
                     /gene="fumC"
                     /locus_tag="ACFOAE_001522"
     CDS             6521..7909
                     /gene="fumC"
                     /locus_tag="ACFOAE_001522"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045239 - tricarboxylic acid cycle
                     heteromeric enzyme complex [Evidence IEA];
                     GO_function: GO:0004333 - fumarate hydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006106 - fumarate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HFC6884986.1"
                     /translation="MNTRTEHDTMGNVEVPSEAYWGAQTQRSRNNFKIGGETLPQPLI
                     YALALVKKAAAATNVSLGRIKPEQADLITQAADDVLNGRLDGQFPLVVWQTGSGTQSN
                     MNMNEVLANRANEIAGMGLAAYRPVHPNDHVNHAQSTNDAFPTAIHVAAAIEINRHLI
                     PAVKALRDTLDKKAQAFAPIVKIGRTHLQDATPLTLGQEFSGYVSQLDHGLGRLNDAL
                     KGLYELALGGTAVGTGLNSHPEYAEKAAAKLAELSGLPFVSAPNKFEALGGRDAAVAA
                     SGALKTLAASLNKIANDIRWLASGPRCGLGEIKIPENEPGSSIMPGKVNPTQCEAMTM
                     VCCQVFGNDVTIGMAGASGNFELNVYMPVIAYNLLQSIRLLGDACNSFNEHCAIGIEP
                     VPEKIDYFLHHSLMLVTALNRKIGYENAAKVAKTAYKNNKSLRETAVELGLLTGEEFD
                     ELVVPADMVHPR"
     gene            complement(7974..8897)
                     /locus_tag="ACFOAE_001523"
     CDS             complement(7974..8897)
                     /locus_tag="ACFOAE_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HFC6884987.1"
                     /translation="MENQRPHLGFALALLAAMTWGTLPIAVRQVLKFVDAPTLVWVRF
                     TAAAAVLFVLLALGGRLPKRRDFSWCSFRLLLLGVAGISANFVLIAQGLHYISPTTTQ
                     VLWQISPFTMIVVGVLVFKDRMTAAQKIGLVLLLAGLLMFFNDKFGELSGLGAYAKGV
                     LLCAAGSMAWVCYAVAQKLLSAQFGPQQILLLIYAASAAVFLPFAKPAHIGSLDGTLA
                     WVCFAYCCLNTLIGYGSFGEALKHWEASKVSAVTTLLPVFTVIFSLLGHYVMPDTFAA
                     PDMNGLGYAGALVVVGGAVTAAVGDRLFKRR"
     gene            complement(8873..>9068)
                     /locus_tag="ACFOAE_001524"
     CDS             complement(8873..>9068)
                     /locus_tag="ACFOAE_001524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6884988.1"
                     /translation="LKFRRCFQIARSNSRASAGLFEIKGLELNAKRLNHYCPMRQTGI
                     VRQYGCLKIGKSGWKTKGRT"
BASE COUNT         2297 a         2584 c         2216 g         1971 t
ORIGIN      
        1 cactataata ttttctctcc cgattgaaac aggcgtaaca gaatatgccc gaagctccgg
       61 ctgctttctt gtttaccgcc gcgatattta gagtataata ccaaatttga gcaatagttc
      121 taaaacagtt agaaccattt ttcatgagcc tgactgattc gtacactcgg agaaactgat
      181 gcagaatatt tttgaccctt tggttattcg tggaaaatcc cttaccccca tcgtgcaagg
      241 cggtatgggg gtcggtgttt ccgcatcggg tttatccagc gcggtggcac gtgaaaacgg
      301 tatcggaacg attgccagtg tggatttgcg ccaccttcac gaagacctac tcgccgaatc
      361 ccaaatcaat ccgagtgaag agaaatatac gtctttgaac tgtaccgcat tggacaggga
      421 aatccaaaaa gccaaaagtg cttcagaggg aaaagggctg attgcggtca acgtgatgaa
      481 ggcggtcaaa gaccacgccg catatgtccg ccaggcttgc gaatcagggg cggatgcggt
      541 tgtaatgggt gccggtctgc ctttagacct gccggaaatg accgagggct atcataaata
      601 tgtcgcgctg ctgccgattc tgtccgaatc gcgcggtatt aatatcgttt tgaaacgttg
      661 gatgaaaaaa ggcatattgc ccgatgcgat tgtagtcgaa catcctgccc acgcggccgg
      721 acatttgggt gcatcaaccg ttgaaggcgt aaacgatgcc aagttcgact tcaaacgcgt
      781 gattgaggaa acgtttgaag ttttcaaaag tttagggctg gaaagcgaaa aaatcccgct
      841 tattcttgcg ggaggcatgg caaattttga aaaagtcaaa accgccctaa agaactgggg
      901 agcatccgcc gttcaaatcg gtacggcttt tgccgttacc gaagaaggag atgcacacct
      961 taacttcaaa aaaacgctcg ccggtgcgga aactgaaaaa gtagttgaat ttatgtctgt
     1021 tgccggtttg ccggcgcgcg gtgtccgcac caaattccta gacagctaca tcaagcgtga
     1081 aagcaaactt caggcaaacg ccaaagctga cccgcgccgc tgtacccaag gtttaaactg
     1141 cctgaccagt tgcggcctgc gcgacgggct ttccaaagcc ggacaattct gcattgatat
     1201 ccagcttgcc gccgcattcc gtggagaagt agataaaggc ctgttcttca gaggtaaaga
     1261 cccgctgccc ttcggcaatg ccatccgtac cgtccgcgag acgatacaat atctgctgac
     1321 agggagcgaa cctgttgcaa cgctcggacg ctgacatcag gtaggatttg atttgcaaac
     1381 aaaatgccgt ctgaagggct ttcagacggc gttttttagg ttgtgttccg gaatagtgtc
     1441 gaaaaaacgg agagaaataa aaacgttttg atgtgaacaa aatgccttcc gcattgtgtc
     1501 aggcatacaa cataaatgcc gtctgaagcc cttcagacgg catttttcag gctgcgttcc
     1561 ggaatagtgt cgaaaaaacg gagagaaata aaaacgtttt tatgtaaaca aaacgccttc
     1621 tgcattgtgt caggcataca acacaaatgc cgtctgaagc ccttcagacg gcgtttttca
     1681 ggctgcgttc tggaatagtg ttaaaaaata aacgggatga gatacattta ttttcgtccg
     1741 acaaatcaga ccatcacgcc gaatgatcga ataatgcctg cacggcatta catctggcaa
     1801 agcaatgcaa tgaaaacacg gcttttttat ttgcttccgg cattattgaa aagtttgtcc
     1861 atcggggtca aatcgaccgc attcccttgg ctggtaatcc atttgttctc gacgcgccac
     1921 acgcctgccg cgtcctccac gcgcacatac cagtggttgg tcggcgaaag ggttttgaac
     1981 accgcctcat attccgccct gccgttctgc gcgctgccga cgggcttgag ggcgacggtt
     2041 tgatcgtccg ccttgcgggt cgggtgcatc agcagcaggt tcaaaggctg tttgccgtca
     2101 aactcgccgc cgacaaacac ttttgccgca ttcatatcgg gggaaatgag aacctgcacc
     2161 ccgatatgcc gtctgacggc ttcttcatcc cgatgaagct ggatgtcgat atgtttgccg
     2221 tctttataat aatcgtccgt aaccaaatct gtcgcgtgct gctgcgcgac aaaaaacata
     2281 gcgacgctgg cgatgacgac aaaaatcggc cccgccatca agatccacgg ccagacgtgt
     2341 ttgtaccaag gtttgattga agtgttttga gacacggtta ttctccgata aaggttgcat
     2401 cttcttccaa gacgaccggc ttgccgtcgg gcgcgccgct ttcgcggtat tggaaggtaa
     2461 attcgatagg gtggctgcct ttgtccgcgt attccggaat ggtggacact tggacgggaa
     2521 gggttaccgt ttcgcgcggg gcaaccttga taccgccttc gggcagcccg gtcagggcga
     2581 tttcgtcaaa gcctttgaca cttgcggtaa tgagctgttc tttttcactt ttgttgatga
     2641 tacgcaggct gtatgcgttt tccagccagc ctttggcgtt ttcgcgcacc agtacgccac
     2701 ggtctttcaa aatatcgacc tcgaccattt tgcgcgtgga caaaccggcc aggaaggcaa
     2761 tgataactaa cgccaacacc gcgccgtaac ctgccacgcg cggtctgagc agccgttttt
     2821 taatgtcttt ttcggcatat tcgtgttcca acgcgctttc ggtcgtataa cggattaatc
     2881 cgcgcggata gcccattttg tccataatct catcgcacgc gtcgatacag gcggcgcagc
     2941 cgatacattg gtattgcaga ccgttgcgga tgtcgatgcc gacggggcag acttggacgc
     3001 acatcgcaca gttgatgcag tcgcccaaac ccgcctcttc cttgttgacc gttttcttgc
     3061 gggctccgcg cggttcgccg cgttccgcgt cataagaaac aatcagcgtg tccttgtcga
     3121 acatcgcgct ttggaaacgt gcgtacgggc acatatgcag gcacactttt tcgcgcatga
     3181 tgtgggcgaa gaagaaggtc ataaagccgt aaaacgctgc ggcaaacacc gcgccgccgc
     3241 ctgctgctcc ggtgaataaa tcgggaacga actggcggat agggacaaac cagcctgcaa
     3301 acgtgatgcc cgtccacgcg cagacaagga aaatcaacag gtatttggtg gctttgatgc
     3361 ggattttagt gaaattccac ggcgattttt ccagtttcag ccgtttgttt ctatcgcctt
     3421 cgaccaggtt gtcgatccac agcataattt cggtgtaaac cgtttgcggg caggaatagc
     3481 cgcaccacag tcgcccggca atcgtcgtcc accaaaacag cccgaaggcg caaatcatca
     3541 gcagcaaggc aaggtaaatc aaatcgccca cccccaacga caatccgaaa atgaagaaat
     3601 gccgttcggg gatattgaaa acgacggcct gcctgccgct ccagttgaac cacggaatga
     3661 cgtaaaacac aaactgcgtc gccaatacgg cggcgatacg cagtttggcg aaccgtcctt
     3721 ccgccttttt cggatggatg cgttcgcctt cgggatggat ttgaatcacg ctggctcgcg
     3781 gatcgaatgt ttttttcgct ttcggcgcgg cttttgtttg ttcggacgtg ccgattccgg
     3841 attccggatt gccggcttgg ttttccgtgg tcattctgca ttccttagat ttttgattga
     3901 tggtttgccc gttaccgccg ccgtttgctt ttcagacggc atttttcttg ttttttaagg
     3961 cgttgtgttt caagttttga gaaaatccgt ttttcccaaa atatatttcc gctattgtac
     4021 aactttatgc gccgtccgga tgtatggggc ggatacattt cccatccgca tcaaaacgcc
     4081 tggattttac cttaccgccc gaacaaaatc cgaatacggt taaaaaaaag actaaaaaaa
     4141 ccgacacccc catatcggca gaaccgacgg cgcaagctca taaacaaacg ctatcgacaa
     4201 tccggcacac aatctataac tttttatttc aaaaggaata atggcaggct tcgcccgcaa
     4261 atcgaaaatc cttccccgcc tgtcccctgc cgccgccttc ccacgcgtcc gcccttttct
     4321 tgaaagcata agcgaatcgg gcgataatca acgccgtctg accatccact tatccgaaac
     4381 accagcaagg aaaatacaaa atgtctcaac tggcaaacgc aatccgcttc ctctccgcag
     4441 atgccgttca aaaagcaaat tccggccacc ccggcgcgcc tatgggtatg gcggaaatgg
     4501 cggaaacatt gtggacgaaa ttcctcaatc acaatcccgc caaccccaaa ttctacaacc
     4561 gcgaccgctt cgtcctctcc aacggccacg cgtctatgct gttgtacagc ctgctgcacc
     4621 tgaccggcta caatctgagc attgaagact tgaaaaactt ccgccaactg cacagcaaaa
     4681 cccccggcca tcccgaatac ggctacaccg acggcgtgga aaccacgacc ggcccgttgg
     4741 ggcaagggat tgccaacgcg gtgggtatgg cattggcaga aaaaatcctt gccgccgaat
     4801 ttaataaaga cggtttgaac atcgtcgatc attacaccta cgtctttatg ggcgacggct
     4861 gtctgatgga aggcgtatcg cacgaagcct gttcgctcgc cggcaccttg ggcttgggca
     4921 aactgattgt tttgtatgat gacaacaata tttccattga tggtaaagtg gacggctggt
     4981 ttaccgaaaa catcccgcaa cgctttgaaa gctacggctg gcacgtcgtt cccaatgtaa
     5041 acggtcatga caccgccgcc attcaagccg ccatcgaagc cgcacgtgcc gaaaccggca
     5101 aaccgtccat catctgctgc aaaaccttaa tcggcaaagg cagtgccaac aaagaaggca
     5161 gccacaaaac ccacggcgca cctttgggcg cggacgaaat cgaagccacg cgcaaacatt
     5221 tgggctggac ttaccccgcc tttgaaatcc cgcaagaaat ttacgatgcg tggaatgcca
     5281 aagaacaagg cgcgaaactg gaagccgact ggaacgaact gttcgcgcaa tatcaagcca
     5341 aatatcctgc cgaagccgca gaatttgtgc gccgtatgga taaaaaactg ccggaaaact
     5401 ttgacgagta cgttcagacg gcattgaaag aagtgtgcgc caaagccgaa accatcgcta
     5461 cccgcaaagc cagccaaaac agcatcgaaa tcttggcaaa agagctgccc gaactggtgg
     5521 gcggttcggc cgacctgacc ccgtccaacc tgaccgactg gtcaaacagc gtctccgtta
     5581 cccgcgacaa aggcggcaac tacatccact acggcgtgcg cgagttcggt atgggtgcga
     5641 ttatgaacgg tcttgccctg cacggcggca tcaaaccatt cggtgcgacc ttcctgatgt
     5701 tcagcgaata cgagcgcaac gccctgcgta tggcggcact gatgaaaatc aaccctgtat
     5761 ttgtgttcac ccacgattcc atcggtttgg gcgaagacgg tccgacccac caacccatcg
     5821 agcaaaccgc caccctgcgc ctgattccga atatggatgt atggcgtccg tgcgacaccg
     5881 ccgaatcctt ggtggcatgg gcggaagcgg caaaagccga agaccatccg tcctgcctga
     5941 ttttcagccg tcaaaacctg aaattccaag cacgcaacga acaacaactg aacgacatca
     6001 aacgcggcgg ctacgtcatc agcgaagccc aaggcaacgc ccaagccgtt atcattgcca
     6061 ccggttccga agtcgagctg gctttggaag ctcaaaaagc cctcgccgca caaaacatcg
     6121 ccgtacgcgt tgtttccatg ccttctacca atatattcga ccgccaagac gccgcctata
     6181 aagccgctat cctgcccgaa ggtctgccgc gcgttgccgt agaagccgga cacgccgacg
     6241 gctggtacaa atacgtcggt ctgaacggcg cagtcgtcgg catcaaccgc ttcggcgaat
     6301 ccgcccctgc cgacttactc ttcaaagcat tcggctttac cgtggacaat gtggtcgata
     6361 cagtgaaatc agtgctgtaa ccccactcct aaacaaatgc cgtctgaacg cttttcagac
     6421 ggcatttttt tgccctcccg ccttgatgct tcctcattcc accaatctcc attataatat
     6481 ttgcgaatca ctcttattca catttcaaaa ggagaaacgt atgaacactc gcaccgaaca
     6541 cgacaccatg ggcaatgtcg aagtcccgtc cgaagcctat tggggcgcgc agacccagcg
     6601 cagccgcaac aatttcaaaa tcggcggcga aaccctgccg cagccgctga tttatgcttt
     6661 ggcgctggtg aaaaaagccg ctgccgccac caatgtttcc ctcggcagga ttaagcccga
     6721 acaggcggat ttgattacgc aggcggcgga tgatgtgttg aacggcaggc ttgacggaca
     6781 gtttccttta gtggtttggc agaccggctc cggcacgcag tccaatatga acatgaacga
     6841 agtgctggcg aaccgcgcca acgaaatcgc cggtatgggt ttggcggcgt accggcccgt
     6901 ccatcccaac gaccatgtga accacgcgca atcgaccaac gacgcgttcc caaccgccat
     6961 ccacgtcgcc gccgcgattg aaatcaaccg ccaccttatt ccagcggtaa aagccttgcg
     7021 cgatacattg gacaaaaaag cccaagcttt cgcccccatc gtcaaaatcg gccgcaccca
     7081 cttgcaggac gcaacgccac tgactttggg acaagaattt tccggctacg tttcccagct
     7141 tgaccacggc ttaggccgtc tgaacgacgc gctcaaaggt ttatacgaac tcgctttggg
     7201 cggcacggcg gtcggtacgg gtttgaacag ccatcccgaa tacgccgaaa aagccgccgc
     7261 caaactcgcc gaattgtccg gcttgccgtt tgtcagcgcg ccgaacaaat ttgaagcctt
     7321 gggcggacgc gatgccgccg ttgccgcttc gggcgcattg aaaacgctgg cggcaagcct
     7381 gaataaaatc gccaacgaca tccgctggct ggcaagcggc ccgcgctgcg gtttgggcga
     7441 aatcaaaatc cccgaaaacg agccgggttc gtccatcatg ccgggcaaag tcaacccgac
     7501 ccaatgcgaa gcgatgacca tggtgtgctg ccaagtgttc ggcaacgacg ttaccatcgg
     7561 catggcgggc gcgtcgggca atttcgagct gaacgtctat atgcccgtta tcgcctacaa
     7621 cctcttgcaa tccatccgcc tcttgggcga cgcgtgcaac agcttcaacg aacactgcgc
     7681 catcggcatc gaacccgtac cggaaaaaat cgactatttc ctgcaccatt ccctgatgct
     7741 cgttaccgcg ttaaaccgta aaatcggtta cgaaaacgcc gccaaagtcg ccaaaaccgc
     7801 ctacaaaaac aacaaatcgt tgcgcgaaac cgccgttgag ttgggcttgc tgacgggcga
     7861 agaatttgac gaactggtcg ttcctgccga tatggttcat ccgcgctaat ctttccctca
     7921 aataaaatgc cgtctgaaac ctcgttcgga cggcattttc cgttgcctgc gaactagcgg
     7981 cgtttgaaca gcctgtcccc caccgccgcc gtaaccgcac ccccgaccac gaccagtgcg
     8041 ccggcataac ccaaaccgtt catatccggc gcggcaaaag tatcaggcat cacataatgc
     8101 ccgagcaaag aaaatattac ggtaaacacg gggagcaagg ttgttaccgc gctgactttg
     8161 gaagcctccc aatgtttcaa cgcctcgccg aacgagccgt aaccgattaa cgtattcaag
     8221 cagcaatacg caaaacaaac ccacgccaac gtaccgtcca aacttccgat gtgtgccggt
     8281 ttggcaaacg gcaggaacac ggcggcactt gccgcataaa tcaacagcag aatctgttgc
     8341 ggtccgaatt gcgccgacag cagcttttgc gccacggcat aacacaccca tgccatactg
     8401 cctgccgcac acagcaacac gcccttcgca tacgcgccca aacccgacaa ctcgccgaat
     8461 ttatcgttaa aaaacataag caaaccggca agcagcaaaa ccaagccgat tttctgagcg
     8521 gcagtcatcc ggtctttaaa caccaacacg ccgacaacaa tcatcgtaaa cggcgaaatc
     8581 tgccacaaaa cctgcgtcgt ggtcggcgaa atataatgca gcccttgggc aatcagcaca
     8641 aagtttgccg aaatgcccgc cacgccgagc agcagcagcc tgaatgagca ccaagaaaaa
     8701 tcccgccgct tcggcagccg cccgcccaat gccagcaaaa caaacaatac cgccgccgcc
     8761 gcggtaaaac gcacccacac cagcgtcggc gcatcgacaa acttcaatac ctgccgcacg
     8821 gcaatcggca gcgttcccca cgtcatcgcc gccaaaagtg ccaacgcgaa gcctaggtgc
     8881 ggcctttggt tttccatcct gattttccta tttttaaaca accgtattgc cggacgatgc
     8941 cggtttgccg catcgggcaa taatggttca agcgtttggc gtttaattcc aaccctttga
     9001 tttcaaacaa accggctgaa gctcggctat tgcttcgcgc tatttgaaaa caccgcctga
     9061 attttaaa
//
LOCUS       DAXIDM010000078         9052 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000078 DAXIDM010000000
VERSION     DAXIDM010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9052
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.078"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..1938
                     /locus_tag="ACFOAE_001525"
     CDS             <1..1938
                     /locus_tag="ACFOAE_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent DNA methyltransferase"
                     /protein_id="HFC6884989.1"
                     /translation="ISPEIFGTLFQSVMDAQERREAGAHYTETANIDKVINGLFLENL
                     RAEFEAVKALKRDKDKKLAAFYQKIQNLQFLDPACGCGNFLIVAYDRIRALEDDIIAE
                     ALKDKTGGLFDSPSVQCRLKQFHGIEIDEFAVLIARTAMWLKNHQCNIRTQIRFDGEV
                     ACHTLPLEDAAEIIHANSLRTPWQAADYIFGNPPFIGSTYQTKEQKNDLESICGHIKG
                     YGLLDYVCNWYVKAAGIMAQHPQVQTAFVSTNSICQGQQVEILWGSLLKQDIEIHFAH
                     RTFQWTSQAAGKAAVHCIIVGFRQKPQMPSEKTLYDYPDIKGEPVKHAAANINPYLID
                     APDVIIAKRSRPVHCEPDMVNGSKPTEGGNLILSTDEKEALIAAEPLAEQYIRPFVGA
                     EEFINGKTRWCLWFHGVSDVKRNHDLKQMPQVQARIQAVKTMREASSDKQTQKDAATP
                     WLFQKIRQPSDGNFLIIPRVSSESRRFVPIGYLSYETVVSDLVFTLPNASLYHFGILS
                     STMHNAFMRTVAGRLESRYRYSNTVVYNNFPFPESCRMPSENDRQDPLRAAVETAAQA
                     VLDARGQYRREAREAGLPEPTLAELYAPDAGYTALDKAHAALDKAVDKAYGYKTGKNT
                     DDEAERTAFLFELYRKAAAIA"
     gene            complement(2740..3423)
                     /locus_tag="ACFOAE_001526"
     CDS             complement(2740..3423)
                     /locus_tag="ACFOAE_001526"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFC6884990.1"
                     /translation="MELVFIRHGQSEWNAKNLFTGWRDVKLSEQGLAEAAAAGKKLKE
                     NGYEFDIAFTSVLTRAIKTCNIVLEESDQLFVPQIKTWRLNERHYGQLQGLDKKQTAE
                     QYGDEQVRIWRRSYDTLPPLLDKDDEFSAHKDRRYAHLPADVVPDGENLKVTLERVLP
                     FWEDQIAPAILSGKRVLVAAHGNSLRALAKHIEGISDEDIMGLEIPTGQPLVYKLDDN
                     LKVIEKFYL"
     gene            3571..5874
                     /gene="parC"
                     /locus_tag="ACFOAE_001527"
     CDS             3571..5874
                     /gene="parC"
                     /locus_tag="ACFOAE_001527"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009340 - DNA topoisomerase IV complex
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFC6884991.1"
                     /translation="MNTKPHASHTDSNTLMLGQYAERAYLEYAMSVVKGRALPEVSDG
                     QKPVQRRILFAMRDMGLTAGAKPVKSARVVGEILGKYHPHGDSSAYEAMVRMAQDFTL
                     RYPLIDGIGNFGSRDGDGAAAMRYTEARLTPIAELLLSEINQGTVDFVPNYDGAFDEP
                     LHLPARLPMVLLNGASGIAVGMATEIPSHNLNEVTQAAIALLKKPTLETADLMQYIPA
                     PDFAGGGQIITPADELRRIYETGKGSVRVRARYEIEKLARGQWRVIVTELPPNANSAK
                     ILAEIEEQTNPKPKAGKKQLNQDQLNTKKLMLDLIDRVRDESDGEHPVRLVFEPKSSR
                     IDTDTFINTLMAQTSLEGNVSMNLVMMGLDNRPAQKNLKTILQEWLDFRTVTVTRRLK
                     FRLNQVEKRLHILEGRLKVFLHIDEVIKVIRESDDPKADLMAAFGLTEIQAEDILEIR
                     LRQLARLEGFKLEKELNELREEQGRLNILLSDENEKRKLIVKEMQADMKQYGDARRTL
                     VEEAGRAVLTQTTADEPITLILSEKGWIRSRAGHNLDLSQTAFKEGDRLKQTLEGRTI
                     LPVVILDSSGRTYTLDAAEIPGGRGDGVPVSSLIELQNGAKPVAMLTGLPEQHYLLSS
                     SGGYGFIAKLGDMVGRVKAGKVVMTADSGETVLPPVAVYASSFINPDCKIIAATNQNR
                     ALAFPIGELKIMAKGKGLQIIGLNAGESMTHTAVSSEPEILIESEGRRGAAHKDRIPI
                     SLLEAKRGKKGKLLPISGSLKQLSSPK"
     gene            5894..7470
                     /locus_tag="ACFOAE_001528"
                     /pseudo
     CDS             5894..7470
                     /locus_tag="ACFOAE_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237220.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            7463..7930
                     /locus_tag="ACFOAE_001529"
     CDS             7463..7930
                     /locus_tag="ACFOAE_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009117578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC6884992.1"
                     /translation="MTELQHPVLVVDDETDILDLMEMTLMKMGLRVHTASGVAEAKNK
                     LDSQRYSLVLTDMRMPDGSGLEVVQHINSRLLDTPVAVITAFGNADQAQEALRCGAFD
                     PDTMQIQDYLDQIERDIIEQTLKQTEGNRTQAAKRLGISFRSMRYRMERLNIG"
     gene            8034..8786
                     /locus_tag="ACFOAE_001530"
     CDS             8034..8786
                     /locus_tag="ACFOAE_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC6884993.1"
                     /translation="MTDILIDNTATETVRTLIRAFPLVPVSQPPEQGSYLLAEHDTVS
                     LRLVGEKSSVIVDFASGAAQYRRTKGGGELIAKAVNHTAHPTVWDATAGLGRDSFVLA
                     SLGLAVTAFEQHPAVACLLSDGIRRALLNPETQDTAARITLHFGNAAVQMPALVQTQG
                     KPDIVYLDPMYPERRKSAAVKKEMTYFHRLVGEAQDEAALLHTARQTAKKRVVVKRPR
                     LGEHLAGQAPAYQYTGKSTRFDVYLPYGTDKG"
BASE COUNT         2217 a         2837 c         2200 g         1798 t
ORIGIN      
        1 atcagtcccg aaatcttcgg cacgctcttc caatcagtca tggacgcaca agagcggcgc
       61 gaagcgggcg cacactacac cgaaaccgcc aacatcgaca aagtcatcaa cggccttttt
      121 ttagaaaacc tgcgcgccga atttgaagcc gtcaaagccc tcaaacgcga caaagacaaa
      181 aaactcgccg ccttctacca aaaaatccaa aacctgcaat tcctcgaccc ggcctgcggc
      241 tgcggcaact tccttatcgt cgcctacgac cgtatccgcg ccctcgaaga cgacatcatc
      301 gccgaagcgc tcaaagacaa aacaggcggc ttattcgaca gcccgtccgt ccaatgccgt
      361 ctgaaacagt ttcacggcat cgaaatagac gaatttgccg tcctcatcgc ccgcaccgcc
      421 atgtggctca aaaaccacca atgcaacatc cgcacgcaaa tccgcttcga cggcgaagtc
      481 gcctgccata cgctgccgct cgaagacgcc gccgaaatca tccacgccaa cagcctccgc
      541 acaccttggc aggcggcgga ctacatcttc ggcaatccgc cctttatcgg ctcgacctac
      601 caaaccaaag agcagaaaaa cgacctcgaa agcatctgcg gccatatcaa aggctacggc
      661 ctgttggatt acgtctgcaa ctggtatgtc aaagccgccg gtatcatggc gcagcatccc
      721 caagttcaga cggcatttgt ttccaccaat tccatctgcc aaggccagca ggtcgaaatc
      781 ctttggggca gccttttgaa gcaagacatc gaaatccact ttgcccaccg cacctttcaa
      841 tggacgagcc aagccgcagg caaagccgcc gtccactgca tcatcgtcgg cttccgccaa
      901 aagccgcaaa tgccgtctga aaaaaccctc tacgactatc ccgacatcaa aggcgaaccc
      961 gtaaaacacg ccgcggccaa catcaatccg tatctgattg acgcgcccga tgtgattatt
     1021 gccaagcgca gccgtcccgt acattgcgaa cctgacatgg tcaacggaag caaaccgacc
     1081 gaaggcggca accttatcct ttcaaccgat gaaaaagaag ccctgattgc cgccgaaccc
     1141 ttggcggaac aatacatccg tccctttgtc ggcgcagagg aatttatcaa cggcaaaacc
     1201 cgttggtgcc tgtggtttca cggcgtatcc gacgttaaac gcaaccacga cctgaaacag
     1261 atgccccaag ttcaagcccg tattcaggca gtcaaaacca tgcgcgaagc cagcagcgac
     1321 aaacaaactc aaaaagatgc agcaaccccg tggctttttc aaaaaatccg ccagccttca
     1381 gacggcaatt ttctgattat cccacgcgtc tcatccgaaa gccgccgttt cgtccccatc
     1441 ggttatctat catatgaaac agttgtcagc gatttggtat ttacccttcc aaacgccagc
     1501 ctctaccact tcggcatcct cagctccacc atgcacaacg cctttatgcg taccgttgcc
     1561 ggccgtctgg aaagtcgtta ccgctattcc aataccgttg tgtacaacaa cttccccttc
     1621 cccgaaagct gccggatgcc gtctgaaaac gaccgccaag acccgctccg cgccgccgtc
     1681 gaaaccgccg cccaagccgt cctcgacgcg cgcggacaat accgccgaga agcgcgggaa
     1741 gccggtttgc ccgagccgac cctcgccgaa ctctatgcgc ccgacgcagg ctataccgcc
     1801 ctagacaaag cccacgccgc cctcgacaag gcagtcgata aagcctacgg ctacaaaaca
     1861 ggcaaaaaca ccgacgacga agccgaacgc accgccttcc tgttcgagct gtaccgcaag
     1921 gcggcggcaa ttgcgtagta gttgcgtagt agttgcgtag gatagttgcg tagggtgggc
     1981 ttcagcccac caactcccac caactcccac catcttcacc ctaaaacccc gtcatctccg
     2041 caaaagcaat tgcgtagggt gggcttcagc ccaccgtttt tcttcatttt cggttgttga
     2101 ttggcaggct gaagcccacc ctgcggttac aaaaatcccg tcattcccgc gcaggcggga
     2161 atccagacct ttcggggcgg aaacttatcg gataaaacga tttcccctgc atcctggatt
     2221 cccactttca tgggaatgac gggatatagg tttccctacg gacgtgttca gattcccgcc
     2281 ttcgcgggaa tgacggcgga gaagtttctg tctttccgat aacttaccgt aacttaaaat
     2341 cccgtcatta ccgcaaaagc agttgctacg gttacaaaaa tcccgtcatc cccacgaaag
     2401 cgaaaatcct gcctgtcgga tttcggtttt ttcgggcgtt tcgggaactt ataaatcgtc
     2461 attcccgcgc aggcgggaat ccagaacgcg ggacggcggc aatattcaaa ggttgtctga
     2521 aaattcagag gttctagatt cccgcctgcg cgggaatgac ggcggagcgg tttctgcttt
     2581 tccgataaat gaccgcaacc taaaacccat ccttcccacg aaaacagaaa aacaaaaacc
     2641 taaaatcccg tcgttctcgc gaaagcagtt gctacgttta ccgtcaaaaa tgccgtctga
     2701 acgctcaagc cttcagacgg cattttttat ttcacaccct tacaggtaga atttttcgat
     2761 gactttcaaa ttgtcgtcca atttgtacac caacggctga ccggtcggga tttccaagcc
     2821 catgatgtct tcgtcggaaa tgccctcgat gtgttttgcc agcgcgcgca gggagttgcc
     2881 gtgcgccgcc accaagacgc gtttgccgct caaaatcgcg ggggcgattt ggtcttccca
     2941 aaacggcaat acgcgctcca gcgttacttt caggttttcg ccgtcgggta cgacatcggc
     3001 aggcagatgg gcatagcggc ggtctttgtg tgcggaaaac tcatcatctt tgtccaaaag
     3061 cggcggcagg gtgtcgtagc tgcgccgcca gatgcggact tgctcgtcgc cgtattgttc
     3121 ggcggtttgt tttttgtcca aaccttgcag ttggccgtag tggcgttcgt tcagccgcca
     3181 tgttttgatt tgcggtacga acagttggtc ggattcttcc aaaacgatgt tgcaggtctt
     3241 aatcgcgcgg gtcaggacgg atgtgaaggc gatgtcgaac tcatagccgt tttctttcag
     3301 ttttttaccg gcggcggcag cctcggcaag cccctgctcg ctcagcttca cgtcgcgcca
     3361 gcctgtaaac aggtttttcg cgttccattc gctttgtccg tggcggataa ataccagttc
     3421 catatcgtct ccaatgtgtg aaagtgggaa agccttattt ataacatatt ttcacatttc
     3481 ccgtatttga ttcagattca gacacgcgcc cactatggtt tgccgttttg atttacaata
     3541 atgccctttg ctttacattc cgcatacaca atgaatacga aaccgcacgc ttcccatacc
     3601 gattccaata cgctgatgct cggtcaatac gccgaacgcg cctatctcga atacgccatg
     3661 agcgtggtca aaggccgcgc gctgcctgaa gtttcagacg gccagaagcc cgtgcagcgg
     3721 cgcattttgt ttgccatgcg cgatatgggt ttgacggcgg gggcgaagcc ggtgaaatcg
     3781 gcgcgcgtgg tcggcgagat tttgggtaaa taccacccgc acggcgacag ttccgcctat
     3841 gaggcgatgg tgcggatggc gcaggatttt accttgcgct atcccttaat cgacggcatc
     3901 ggcaacttcg gctcgcgcga cggcgacggg gcggcggcga tgcgttacac cgaagcgcgg
     3961 ctcacgccga ttgcggaatt gctgttgtcc gaaatcaatc aggggacggt ggattttgtg
     4021 ccgaactacg acggcgcgtt tgacgaaccg ctgcacctgc ccgcccgcct gcctatggtg
     4081 ttgctcaacg gcgcgtcagg cattgcggtg ggcatggcga ccgagattcc gtcgcacaat
     4141 ttgaacgaag ttacgcaggc ggcgattgcg ttgttgaaaa agccgacgct ggaaaccgcc
     4201 gacctgatgc aatacattcc cgcacctgat tttgccggcg gcggtcaaat catcacgccg
     4261 gcggacgaat tgcgccggat ttatgaaacc ggcaagggca gcgtgcgcgt gcgtgcgcgt
     4321 tatgaaatcg aaaaattggc gcgcggacaa tggcgcgtca tcgtaaccga gctaccgccg
     4381 aacgccaatt ccgccaaaat ccttgccgaa atcgaagagc agaccaaccc gaaaccgaaa
     4441 gcgggcaaaa agcagctcaa ccaagaccag ctcaatacca aaaagctgat gctggattta
     4501 atcgaccgcg tgcgcgacga gtccgacggc gaacatcccg tgcgccttgt atttgaacca
     4561 aaatccagcc gcatcgatac cgataccttc atcaacacgc tgatggcgca aacttcgctg
     4621 gaaggcaatg tgtccatgaa cttggtgatg atggggctgg acaaccgccc cgcgcagaaa
     4681 aacctgaaaa cgattttgca ggaatggctg gatttccgca ccgtaaccgt aacacgccgt
     4741 ctgaaattcc gtttgaacca agtggaaaaa cggctgcaca tcctcgaagg ccgtctgaaa
     4801 gtctttctgc acatcgacga agtgattaaa gtcatccgcg aatcagatga cccgaaagcc
     4861 gatttgatgg cggcgttcgg gctgaccgaa atccaagccg aagacatttt ggaaatccgc
     4921 ctgcgccagt tggcgcgttt ggagggtttc aaactcgaaa aagaattgaa cgagttgcgc
     4981 gaggaacaag gccgtctgaa catccttttg agcgacgaaa acgaaaaacg caagctgatt
     5041 gtcaaagaga tgcaggcgga tatgaaacaa tacggcgacg cgcgacgcac gctggtggaa
     5101 gaggccggac gcgccgtgct gacgcagacc accgccgacg aacccatcac gctgatcctg
     5161 tcggaaaaag gctggatacg cagccgcgcc ggacacaatc tcgatttgag ccaaaccgcg
     5221 ttcaaagaag gcgaccgcct caaacaaacc ctcgaaggca gaacgatttt acccgtcgtc
     5281 attctcgatt catcgggcag aacctacacc cttgatgccg ccgaaatccc cggcgggcgc
     5341 ggcgacggcg tgccggtttc atccttgatc gagctgcaaa acggcgcgaa acccgttgcg
     5401 atgttgacag gattgccgga acaacattat ttattatcaa gcagcggcgg ctacggcttc
     5461 atcgccaaac tgggcgatat ggtcgggcgc gtgaaagcgg gcaaagtagt gatgaccgca
     5521 gacagcggcg aaaccgtttt gccgccggtt gccgtctatg cctcctcgtt catcaacccc
     5581 gactgcaaaa tcattgccgc caccaatcaa aaccgcgccc tcgccttccc catcggcgaa
     5641 ttgaaaatta tggcgaaagg caaagggctg caaatcatcg gattaaacgc cggcgaatcg
     5701 atgacgcata ccgccgtttc ttccgagccg gaaatcctga ttgaaagcga aggcaggcgc
     5761 ggcgcagcgc acaaagaccg catccccatc tccctgcttg aggcaaaacg cggcaaaaaa
     5821 ggcaaactat tacccatatc gggcagcctg aaacagcttt cttccccgaa ataaacccga
     5881 ctctgcacat actatggtaa tttccaatac ccgcgaactt gagaaactca aagaccggat
     5941 tcccaatctg atcaacatcg cccgcatcgc catcgtcttc cccctgctga ttatgcatat
     6001 cttcgggttg gaggtcagcg gacatgaaaa cctgcacgct tcgtggacgg cgtgggcatt
     6061 ttatgtttgg ctcgccattt cctgctggct gattttcttt tccatcatcc atccgcattg
     6121 gcaatggcag tcgctgaaaa tgccgcgttt cagcgcggtg gcggacatca cgatgatcgg
     6181 cgtgctgacc tacctgttcg gcggcatcga ttccggcttc ggcatcctga ttctgccctt
     6241 cgtcgtctgc tcctgcctgc tcagctacgg gcgttacccc ctgctctatg ccagctacgc
     6301 cgccatcctg ctgatattca acgccattgc cgacggcgat atcggcaaat atccgcacat
     6361 atcggatgcc cgaaccgcct cggcaacctt catcctcgtc gccgcctcct atctttccgc
     6421 catcttcacc tcactgtcgg tcagatacat cgacagcgcc ggccaactgg cccgcgacaa
     6481 ccacctcgcc taccggcgca tcaaaggctt gagccaaacc gtactcgaac gcgttcaaga
     6541 agccgtcgtc gtcatcaata ccgaagggct ggcggtgctg ttcaaccgga aggcgaaaga
     6601 ccttttcccc gcactcgaaa tcggacggcg cgccgacctg tccgattctg ccgccgaact
     6661 gtgggaccaa gcctctccgc acactttcga atacgtcctc ggcacactcg gcctgaccgc
     6721 ccgcatccgc gccgtgccga tgaacaaaga gccggacaag ctgcttatcc tctacatccg
     6781 cccgcaaagc gaaattcagg cagaagccct gtccgtcaaa cttgccgcgc tcggacaact
     6841 gaccgccaac cttgcccacg aaatccgcaa cccgatgtcc gccatccgcc acgccaacga
     6901 cctgctgcgc gaaaatatgg aagcgggggc ggcagatccg ttcaacgcca aattgtgcaa
     6961 aatcatcgac ggcaacgtct gccgcatcga caaaatgctc gaagacattt cctcactcaa
     7021 caagcgcaac aaaaccgaac gcgaaaccat cggcctgata ccgttttggg aagaattcaa
     7081 acaagagttc ctgctcggcc atcccgatgc cgccggctgc atccgcttgg atatgcaggg
     7141 caatcacccg accgcctatt tcgatcccgc ccacctgcgg caaattatgt ggaacctcgc
     7201 caacaacgcg tggcggcaca gccgcaaaca gcccggctcg atttccgtca ccatccgccc
     7261 cgcgcaaaaa aacaccgtct gcatcctctt tgccgaccgc ccgaagtgca ggaacacctg
     7321 ttcgaaccct tttacaccac ggcggaaaac ggcaccggcc tcgggctgta tgtcgcccgc
     7381 gaactggcgc acgccaattt cggcgatttg acctacctac cggaagccaa atgtttcgaa
     7441 ctcacattac cggaaaaaac caatgactga actgcaacac cccgtcctcg tcgtcgatga
     7501 cgaaaccgac attctcgacc tgatggaaat gaccctgatg aaaatgggct tgcgcgtcca
     7561 taccgcgtca ggcgttgccg aagccaaaaa caagctcgac agccaacgct attcgctcgt
     7621 cctgaccgat atgcgtatgc cggacggctc ggggctggaa gtcgtccaac acatcaacag
     7681 ccgcctgctc gatacgccgg ttgccgtcat caccgccttc ggcaacgccg atcaggcaca
     7741 ggaagcgttg cgttgcggcg cgttcgaccc cgataccatg cagatacagg actatctcga
     7801 ccaaatcgaa cgcgacatta tcgaacaaac cctcaaacaa accgaaggca accgcacgca
     7861 ggccgccaaa cgcttgggca tcagcttccg ttccatgcgc taccgtatgg aacgcctcaa
     7921 catcggctga cgacaaaacg gcatccgcac catctccgcc cacccgaaaa aatgccgtct
     7981 gaaacggcac gggaaagcgg gttcgcccca cgcccgaacg gacacaaaac accatgaccg
     8041 acatccttat tgacaacacc gccaccgaaa ccgtccgcac cctgatacgg gcattccccc
     8101 ttgtgcccgt ttcccaaccg cccgaacaag gcagttacct ccttgccgaa cacgataccg
     8161 tcagcctcag gcttgtcggg gaaaaaagca gcgtcatcgt cgattttgcc tccggcgcgg
     8221 cacaataccg gcgcacaaaa ggcgggggcg aactcatcgc caaagccgtc aaccacaccg
     8281 cgcaccccac cgtttgggac gcaaccgcag gattggggcg cgacagcttc gtcctcgcct
     8341 cgctcgggct ggccgttacc gccttcgagc aacatcccgc cgtcgcctgc ctgctttcag
     8401 acggcatccg ccgcgccctc ctcaatcccg aaacgcaaga caccgccgcg cgcatcaccc
     8461 tgcatttcgg caacgccgca gtacaaatgc ccgcacttgt tcaaacacaa ggcaaacccg
     8521 acatcgtcta tctcgacccc atgtatcccg aacgccgcaa aagtgccgcc gtcaaaaaag
     8581 aaatgaccta cttccaccgg ctcgtcggtg aagcgcaaga tgaggccgcc ctcctccata
     8641 ccgcacgcca aacggcaaaa aaacgcgtcg tcgtcaaacg cccccgcctc ggcgaacacc
     8701 ttgccggaca agcccctgcc taccaataca ccggcaaaag cacccgcttc gacgtttacc
     8761 tgccctacgg gacggacaag ggataacgcc cataaaacaa gacaccgaaa aatttgccgt
     8821 tcttatgcaa acgagaaacc ggtttttgcg tttcgactgt tttggataaa tcatcacacc
     8881 ttaaagtttg tcattcccac ggaagtggga atccagaaat gaaaagcaac aggaatttat
     8941 cgtaaatgac cgaaaccgaa cggactagat tcccgcctgc gcgggaatga cgaagtttca
     9001 ggttgctgtt tttaagttgc tgtttcgggt tgctgttttt tatggaaatg ac
//
LOCUS       DAXIDM010000079         9006 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000079 DAXIDM010000000
VERSION     DAXIDM010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 9006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9006
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.079"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(494..2074)
                     /gene="purH"
                     /locus_tag="ACFOAE_001531"
     CDS             complement(494..2074)
                     /gene="purH"
                     /locus_tag="ACFOAE_001531"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFC6884994.1"
                     /translation="MSVIKRALISLSDKAGAVEFAQTLHKLGVEILSTGGTAKLLADA
                     GVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLDEHVAKMEEHGIGNIDLVCV
                     NLYPFAATIAKPNCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELE
                     ANNGALSDKTRFNLSRKAFSHTAQYDGMISNYLTSLSDDVLSGQPQIGEFPSRFNQSW
                     IKVQDMRYGENPHQRAAFYRDIDPAAGSLSAYKQLQGKELSYNNIADADAAWEAVKSF
                     DAPACVIVKHANPCGVAVAADTLTAYKLAYVTDTTSAFGGIIAFNREVDGETVKQITD
                     NQFMEVLMAPKFTTEALDIAAAKKNVRVLEIPLEAGANRFELKRVGGGLLVQTPDIHR
                     LSRADLKVVSKRQPTEQEWNDLLFVWNVAKYVKSNAIVFGKGGQTYGIGAGQMSRVDS
                     TRIAARKAQDANLDLNGACAASDAFFPFRDGVDVIAEQGIKAIIHPAGSMRDQEVFDA
                     ADEHGIAMVVTGVRHFRH"
     gene            complement(2235..3458)
                     /locus_tag="ACFOAE_001532"
     CDS             complement(2235..3458)
                     /locus_tag="ACFOAE_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HFC6884995.1"
                     /translation="MGRRKLWFALAAAGVIGGLVGIVLTELMHFIQHTAYGYGTDGVS
                     ISFREGVAQASGMRRVAVLTLCGAVAGSGWWLLKRFGKPQIEIKAALKQPLQGLPFLT
                     TVFHVLLQIITVGLGSPLGREVAPREMTAAFAFAGGRRLGLDEGEMRLLIACASGAGL
                     AAVYNVPLASTLFILEAMLGVWTQQAVAAALLTSVIATAVARIGLGDVQQYHPANLAV
                     STSLLWFSAVIGPILGATAVFFQRTAQKFPFIKRDNIKIIPLAVCMFALIGAIAVWFP
                     EILGNGKAGNQLTFGGLTDWQHSLELTAVKWLVVLMALAAGAYGGLITPSMMLGSTIS
                     FAAAAAWNSVFPEMPSESAAVVGAAVFLGVSLKMPLTAIVFVLELTYAPLSLLLPLCI
                     GMAGALGTSGKMGFK"
     gene            complement(3522..4355)
                     /gene="serB"
                     /locus_tag="ACFOAE_001533"
     CDS             complement(3522..4355)
                     /gene="serB"
                     /locus_tag="ACFOAE_001533"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036424 - L-phosphoserine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HFC6884996.1"
                     /translation="MPHALVLQFPSAEALPSDFPSRLPEPDYADEKRMRFIVEEGFSL
                     SEADAALLGSRQIDHAVLPDMDFDELGLIVSDMDSTLITIECVDEIAAGVGLKDKVAE
                     ITERSMRGELDFEQSLRSRVALLAGLDEQILADVYENVLKLSPGAEFLLDECKRHDVK
                     FLLVSGGFTFFTERLQQRLGFEYQHANVLEIENGRLTGRLKGRIIDAQAKADLLREYR
                     SRLGLQPHQVLAMGDGANDIPMLKEAGIGVAYRAKPKAQAAADACINFGGLERVRGLF
                     G"
     gene            4645..6186
                     /locus_tag="ACFOAE_001534"
     CDS             4645..6186
                     /locus_tag="ACFOAE_001534"
                     /EC_number="7.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HFC6884997.1"
                     /translation="MKIGIPRESLSGETRVACTPATVALLGKLGFETVVESGAGLAAS
                     LDDAAYQTAGATVADKAAVWACPLIYKVNAPSEGELPLLNEGQTIVSFLWPRQNEALV
                     EALRAKKVNALAMDMVPRISRAQALDALSSMANISGYRAVIEAANAFGRFFTGQITAA
                     GKVPPAQVLVIGAGVAGLAAIGTANSLGAVVRAFDTRLEVAEQIESMGGKFLKLDFPQ
                     ESGGSGDGYAKVMSDEFIAAEMKLFAEQAKEVDIIITTAAIPGKPAPKLITKEMVESM
                     KSGSVIVDLAAATGGNCELTRPGELSVTGNGVKIIGYTDMANRLAGQSSQLYATNLVN
                     LTKLLSPNKDGEITLDFEDVIIRNMTVTHDGEITFPPPPIQVSAQPQQTPSEKAAPAA
                     KPEPKPVSLWKKLAPAVIAAVLVLWVGAVAPAAFLNHFIVFVLACVIGYYVVWNVSHS
                     LHTPLMSVTNAISGIIVVGALLQISQGNGFVTLLAFIAILIASINIFGGFFVTRRMLN
                     MFKKG"
     gene            6190..6573
                     /locus_tag="ACFOAE_001535"
     CDS             6190..6573
                     /locus_tag="ACFOAE_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HFC6884998.1"
                     /translation="MTFAYWCILIACLLPLFCAAYAKKTGGFRFSDNHHPRDFLARTQ
                     GAAARAHAAQQNSFEAFAPFAAAVLTAHATGNAGQATVNTLAGLFILFRLAFIWCYIA
                     DKAALRSLMWAGGFACTVGLFVAAA"
     gene            6639..8024
                     /gene="pntB"
                     /locus_tag="ACFOAE_001536"
     CDS             6639..8024
                     /gene="pntB"
                     /locus_tag="ACFOAE_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003676645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008750 - proton-translocating NAD(P)+
                     transhydrogenase activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HFC6884999.1"
                     /translation="MSSGLVTAAYIVAAILFIFSLAGLSKQETAKQGCYSGIAGMAVA
                     LFVTVFSDNTHGLGWIIIAMLIGAAIGIYKAKKVEMTEMPELIALLHSFVGLAAVLVG
                     FNSYIEPGNVSHDMHTIHLVEVYLGIFIGAVTFTGSLVAFGKLNGKISSSPLQLPAKH
                     KLNALALAVSFVLLLVFVGINGSGFILLIMTLIALAFGWHLVASIGGADMPVVVSMLN
                     SYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFVSVIAGGFGSDSG
                     TLSSGSQEIGEYREVKAADIAEMLKGANNVIITPGYGMAVAQAQYPVAEITELLRKNG
                     TEVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFPETDVVLVIGANDTVN
                     PAAQTDPNSPIAGMPVLEVWKAKEVVVFKRSMNTGYAGVQNPLFFNENSVMCFGDAKK
                     TVDDILSELKK"
     gene            complement(8232..8675)
                     /locus_tag="ACFOAE_001537"
                     /pseudo
     CDS             complement(8232..8675)
                     /locus_tag="ACFOAE_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005694496.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
BASE COUNT         1992 a         2525 c         2434 g         2055 t
ORIGIN      
        1 tttagattta attcactata cctgcgtaat ggtattgggt actcatcata aacctgcctt
       61 gcattcggtt gtgttgtccg gcaactgtcc ggttgtgtcg atgggttgcc ctgccgctcc
      121 ctgagctacg caacggttgt gtgccttggg tgggcgcggg tggcggccgg gcggtttgtt
      181 gctatgatac agtgattcca atatacaagg gtgggcttca gcccaccgct tccgtcgatt
      241 ccgtcaatgt tacccatttc caccgtcccc gccgaaacca aaaccgccga ctcccgccgg
      301 ttctccaaaa atttttgatg cagcgggctg aagcacaccc tgcatcccac cttttacgaa
      361 tcctcctaca ccctatacaa caccttgaaa atccaccctg tcaggaatac ccgaaccgtc
      421 atccctacct tcacaaaata gcgcaaaatg ccgtctgaaa gcccttcaga cggcattgcc
      481 ttgtttatct gcgttaatgc ctgaaatggc gcacgcccgt tacgaccatg gcgatgccgt
      541 gttcgtccgc tgcgtcaaag acttcttggt cgcgcatgga gcctgcggga tggatgatgg
      601 ctttgatgcc ctgctcggca atcacgtcca cgccgtcgcg gaaggggaag aaggcatcgg
      661 aagcggcaca tgcgccgttg aggtcgagat tggcatcttg cgctttgcgg gcggcgatgc
      721 gggtgctgtc cacgcggctc atttggcctg cgccgatgcc gtaggtttga ccgcctttgc
      781 cgaagacgat ggcgttggat ttgacgtatt tggcgacgtt ccagacgaac agcaaatcgt
      841 tccattcctg ctcggtcggt tggcgtttgg agacgacttt taaatcagcg cggctgaggc
      901 ggtggatgtc gggggtttgt accaacagtc cgccgccgac gcgtttgagt tcgaagcggt
      961 tcgcgcctgc ttcgagcggt atttccaata cgcgcacgtt tttcttggcg gcggcgatgt
     1021 cgagggcttc ggtggtgaac ttcggcgcca tcaaaacttc cataaactgg ttgtcggtaa
     1081 tttgtttgac ggtttcgccg tccacttcgc ggttgaaggc aataatgccg ccgaacgcgc
     1141 tggtggtgtc ggtgacgtag gcgagtttgt aggcggtcaa tgtatcggct gcaacggcga
     1201 cgccgcacgg attggcgtgt ttgacgatca cgcaggctgg cgcgtcaaag gatttgacgg
     1261 cttcccatgc ggcatcggca tcggcgatgt tgttgtaaga caattctttg ccttgaagct
     1321 gtttataagc ggaaaggctg cctgcggcgg ggtcaatatc gcggtagaac gcggcgcgtt
     1381 ggtgcgggtt ttcgccgtag cgcatgtctt gcactttgat ccagctttgg ttgaaccggc
     1441 tggggaattc gccgatttgg ggctggccgc tcaaaacgtc gtctgaaagg gaggtcaggt
     1501 agttggaaat catgccgtcg tattgggcgg tgtggctgaa tgctttgcgt gagaggttga
     1561 aacgggtttt gtcgctcaat gcgccgttgt tggcttcgag ttcggcggca atggcgggga
     1621 agtcggcggt gtcggtaacg atggcgacgt gtttccagtt tttcgcggcg gaacgcacca
     1681 tagtcgggcc gccgatgtcg atgttttcaa tcgcgtcttc cagtgtgcag tttggtttgg
     1741 cgatggtggc ggcgaagggg tagaggttga cacacacaag gtcgatgttg ccgataccgt
     1801 gttcttccat cttggcaacg tgttcgtcca aatcgcgccg acccaaaata ccgccgtgga
     1861 ttttcggatg cagcgttttc acgcggccgt cgagcatttc ggggaagccg gtatagtcgg
     1921 cgacttcaat cacgggaacg cccgcatcgg caagcagttt cgccgtgccg ccggtggaga
     1981 ggatttcgac accgagcttg tgcagggttt gggcaaattc gaccgcgcct gccttgtcgg
     2041 acaggctgat cagggcacgt ttgatgacgg acattggggc ttccttttct gacagttgga
     2101 tggggaaagg ggaacttttt cggggcggta ttatccgcta ttttcagttt tttggcagta
     2161 gatttttgca gatattgttg acaatttaca aagaaatgcc gtctgaaaac ctttcagacg
     2221 gcatttgtcg gcattcattt gaagcccatt tttcccgatg ttcccaatgc ccccgccatg
     2281 ccgatgcaca aaggcagcag cagggacagc ggcgcgtagg tcaattccaa tacgaacaca
     2341 atggcggtca gcggcatttt gagcgatacg ccgagaaaca ccgccgctcc gacgactgcc
     2401 gcgctttcag acggcatttc ggggaaaacg ctgttccacg cggcggcggc tgcaaaagaa
     2461 atggtgctgc cgagcatcat agacggcgta atcagtccgc cgtatgcgcc tgccgccaac
     2521 gccatcaaga caaccagcca tttgacggcg gtcagctcaa ggctgtgttg ccagtcggtc
     2581 aatccgccaa aggtcagttg gttgcctgct ttgccgttgc ccaaaatttc gggaaaccaa
     2641 acggcaatcg cgccgatgag cgcaaacatg cagactgcca agggaataat ttttatgttg
     2701 tcgcgcttga taaaggggaa cttttgggcg gtacgctgga aaaagacggc ggttgcgccc
     2761 agtatcgggc cgatgacggc ggaaaaccaa agtaatgagg tgctgacggc aaggttggcg
     2821 ggatgatact gctgcacgtc gcctaagccg atgcgtgcga cggcggtggc aatgaccgaa
     2881 gtcagcaatg cggcggcgac ggcttgctgc gtccacacgc ccagcatggc ttcgaggatg
     2941 aaaagtgtgg acgcgagcgg tacgttatac acggccgcca aacccgcacc ggacgcacag
     3001 gcaatcaaga ggcgcatttc gccttcgtcc aaacccaacc gcctgccgcc ggcaaaagca
     3061 aacgcggcgg tcatttcgcg cggggcgact tcccgtccga gcggcgaacc gagtccgacc
     3121 gttatgattt gcagcagaac atggaaaacc gtcgtcagaa acggcagccc ctgcaacggc
     3181 tgtttcaagg cggctttgat ttcgatttgc ggcttgccga aacgtttcag caaccaccag
     3241 ccgctgcctg cgaccgcgcc gcacagcgtc agcacggcaa cgcgccgcat accggaagcc
     3301 tgtgccacac cttcgcggaa cgagatggac acgccgtccg tgccataacc gtatgccgta
     3361 tgttgtatga agtgcatcag ttccgtcagc acaatgccga ccaaaccgcc gataacgccc
     3421 gctgctgcca gggcaaacca aagttttctg cgtcccactg tcgttcctgc cgttcaaatg
     3481 ccgtctgaaa acctttcaga cggcatccgt ttcctatccg cctatccgaa caggccgcgt
     3541 acacgctcca aaccgccgaa gttgatacag gcatcggcgg ctgcctgcgc tttcggtttg
     3601 gcacggtaag ccacgcctat gcccgcttct ttgagcatcg gaatatcgtt cgcaccgtcg
     3661 cccatcgcca acacctgatg cggctgcaat ccgaggcggc tgcggtattc gcgcaataaa
     3721 tccgcctttg cctgcgcgtc gatgattctg cctttcagac gaccggtcaa cctgccgttt
     3781 tcaatttcca aaacattggc gtgttggtat tcgaagccga gtcgttgttg cagcctttcg
     3841 gtaaaaaatg tgaacccgcc ggacaccagc aggaatttca catcgtgcct tttgcattcg
     3901 tccaacaaga attccgcacc gggcgagagc ttcaaaacgt tttcataaac gtccgccaaa
     3961 atctgttcgt ccaatcccgc caacagcgca acgcggctgc gcaacgactg ctcgaaatcc
     4021 aactctccgc gcatcgaacg ctcggtaatt tccgctacct tgtcttttaa acccacgcct
     4081 gccgcaattt catcgacgca ttcgatggta atcagcgtcg aatccatatc gctgacaatc
     4141 aaaccgagtt cgtcgaaatc catatccggc aacacggcgt ggtcgatttg acggctgcca
     4201 agcaacgccg cgtccgcctc gcttaaagaa aacccttctt caacgataaa acgcatacgc
     4261 ttttcatcgg cgtaatcagg ttcgggcagg cgggagggga agtcggaagg cagggcttcg
     4321 gcggagggaa attggaggac gagggcgtgc ggcatggcgg taactcaaaa aatgcggatt
     4381 atatagtgaa acggcaaaga atgttacggc gggcgggact gcaatcggaa aatgacttca
     4441 aacgcaaacg gcagtatgtg tcggacaaca cgggaaaatg ccgcaactat tgccagcctg
     4501 atgaaaattc gttataaggg gattatctaa aatatattaa catttgaagt gaatcggttt
     4561 taaaccggta cggcgttgct ccgccctgcc ccgatttaaa tttaacccac gatacatata
     4621 aacaacccga aaaaggattc agagatgaaa atcggcatcc cacgcgagtc attatccggc
     4681 gaaacccgcg tcgcctgtac gcccgccacc gtcgccctgc tgggcaaact gggctttgaa
     4741 accgttgtcg aaagcggtgc aggtttggcg gcaagtttgg acgatgccgc ttaccaaaca
     4801 gcaggcgcaa ccgttgccga caaagcggcg gtttgggcct gccctttgat ttataaggtt
     4861 aacgcgccgt ccgaaggcga gctgccgctt ttgaacgaag gtcaaaccat cgtcagcttc
     4921 ctgtggccgc gccaaaacga ggctttggtc gaagccttgc gcgccaagaa agtcaatgcg
     4981 ctggcgatgg acatggtgcc ccgtatttcc cgcgcgcagg ctttggacgc tttgtcttcg
     5041 atggcaaaca tcagcggcta ccgcgccgta attgaagccg ccaacgcctt cggccgtttc
     5101 ttcaccggtc aaatcaccgc cgccggcaaa gtgccgcccg cgcaggtttt ggtgattggt
     5161 gcaggtgtgg caggtttggc ggcgatcggt acggcaaact cgctcggcgc agtggtacgc
     5221 gcgttcgata cccgcttgga agtggcggaa caaatcgaat cgatgggcgg caagttcctg
     5281 aaactcgact tcccacaaga atcgggcggc agcggagacg gctacgccaa agtgatgagc
     5341 gacgaattta tcgcagccga gatgaagctc tttgccgagc aggcgaaaga agtggacatc
     5401 atcatcacca ccgccgccat tccgggcaaa cccgcgccca agctgattac caaagaaatg
     5461 gtggaaagca tgaaatccgg ctccgtcatc gtcgatttgg cggcggcgac gggcggcaac
     5521 tgcgaactca cccgcccggg cgaattgtcc gtaaccggca acggcgtgaa aatcatcggc
     5581 tacaccgaca tggcaaaccg ccttgccgga cagtcttccc agctttacgc caccaacttg
     5641 gtcaacctga ccaagctgtt aagcccgaac aaagacggcg aaatcacgtt ggacttcgaa
     5701 gacgtgatta tccgcaacat gaccgttacc cacgacggcg aaatcacctt cccgcctccg
     5761 ccgattcaag tttccgccca gccgcagcaa acgccgtctg aaaaagccgc gcctgccgcc
     5821 aagcccgagc cgaaacctgt ttccctgtgg aaaaaactcg cgcccgccgt catcgccgcc
     5881 gtattggtgc tgtgggtcgg cgcggtcgca cccgcagcat tcctgaacca ctttatcgtg
     5941 ttcgtcctcg cctgcgtcat cgggtactac gtcgtttgga acgtcagcca ctcgctgcac
     6001 acaccgctga tgtcggtaac caacgccatc tccggcatca tcgtcgtcgg cgcgctgctg
     6061 caaatcagcc aaggcaacgg tttcgttacc ctgcttgcct tcatcgccat cctgattgcc
     6121 agcatcaata tcttcggcgg cttcttcgta acgcgccgca tgttgaatat gtttaagaaa
     6181 gggtaagcca tgactttcgc ctattggtgc atcctgattg cctgcttatt gccgcttttt
     6241 tgtgcagcgt atgccaaaaa aaccggcgga ttccgcttca gcgacaatca tcatccccgt
     6301 gattttctgg cgcgtaccca aggtgccgct gcccgtgccc atgccgcgca gcaaaacagt
     6361 tttgaagcat ttgcaccatt tgcagccgcc gttttgacgg cacacgcaac cggcaatgcc
     6421 ggacaagcaa ccgtcaacac gcttgccggc ctgttcatcc tgttccgcct cgcctttatc
     6481 tggtgctaca tcgcagacaa agcagcattg cgctcgctga tgtgggcggg cggatttgcc
     6541 tgcaccgtcg ggctgtttgt cgcggctgct tgaaacagat gccgtctgaa cagttcagac
     6601 ggcattaaaa acaaatcatc gaaaatcgga gaatttccat gtcttcagga ctcgtaacag
     6661 cggcgtatat cgttgccgca attttattca tcttctcact ggcggggctg tccaaacagg
     6721 aaaccgccaa acagggctgc tattccggta tcgccggtat ggcggtcgcc ctttttgtaa
     6781 ctgttttttc cgacaatacc cacggactgg gctggatcat catcgccatg ctcatcggcg
     6841 cggcaatcgg catctacaaa gccaaaaagg tggaaatgac cgaaatgccc gaactgattg
     6901 ccctgctgca cagcttcgtc ggcctagcgg cggttttggt cggcttcaac agctatatcg
     6961 agccgggcaa cgtttcgcac gatatgcaca ccatccatct ggtcgaagtc tatttgggca
     7021 ttttcatcgg cgcggtaacc tttaccggct cgctggtcgc attcggcaaa ctcaacggca
     7081 aaatcagcag cagcccgctg caactgcccg ccaaacacaa gctcaacgca ctggcgctcg
     7141 ccgtatcgtt tgtgttgctg ctcgtattcg tcggcattaa cggtagcggc ttcatcctgc
     7201 tgattatgac cctgattgcc ctcgcattcg gctggcactt ggttgcctcc atcggcggcg
     7261 cagatatgcc cgtggtcgtg tccatgctca actcctactc cggctgggcg gccgcagcgg
     7321 caggcttcat gctctccaac gacctgctca tcgttaccgg cgcgctggtc ggctcaagcg
     7381 gcgcgattct gtcctacatt atgtgcaaag ccatgaaccg ctcgtttgtc tcggtaattg
     7441 ccggcggttt cggcagcgac agcggcacat tatcttccgg cagccaagag ataggggaat
     7501 accgagaagt caaagctgcc gatattgccg aaatgctgaa aggcgcaaac aatgtcatca
     7561 ttaccccggg ctacggtatg gcagtcgcac aagcgcaata ccccgttgcc gaaatcaccg
     7621 agcttttacg taaaaacggc accgaagtac gcttcggcat ccaccccgtc gccggccgcc
     7681 tgcccggtca tatgaacgta ctgctcgccg aagccaaagt cccctacgac atcgttttgg
     7741 aaatggacga aatcaacgac gacttccccg aaaccgatgt ggtcttggtc atcggtgcga
     7801 acgacaccgt caaccccgcc gcccaaaccg acccgaacag cccgattgcg ggtatgcccg
     7861 tgttggaagt gtggaaggca aaagaagtcg tcgtcttcaa acgctcgatg aataccggct
     7921 acgcaggtgt acaaaaccca ctgttcttca acgaaaacag cgtgatgtgt ttcggagatg
     7981 cgaagaaaac cgtagatgac attctgtccg aactgaaaaa ataatgccgt ctgaacaatt
     8041 cggcgcaggt tttcaatctg tttgatttga aaaaatcact gcaaaccccg tttatgaagg
     8101 tttgcagtga tttttttgca ttggggcaaa cattttcaga cggcccgtcc gaataagcac
     8161 ctacatctga aactgacaca aaatcaacga aacaaacaaa atccatctcc gtgttgaaga
     8221 tggattttta attagccgaa cactttttcc aagtgtgcct gataatctgc caagtatttt
     8281 tccacttgcg gatttttaac cacatcgtta cataagaatg tcggcaggcg ggtcataccc
     8341 aaaaactcgt tggctttgtg gaagtgcata tacaaaacat caacgccttt gccctcaaag
     8401 aaatcgcctt cgcgggtaaa cgcctcaatc ggcgcattcc aagtcagtga aagcatatgt
     8461 tttttgcctt gcaacaagcc gcctgtgccg tagccctcag tcggattgac gctgtgtctg
     8521 ccgtcgcttt ggtagagttt gccgtgtcca gcggttaata ctccgtctat gtattttttc
     8581 actgtccaag gctcgtgcat ccaccagccc ggcatctgcc aaatcacagc atccatccaa
     8641 acgaattttt cgatttctgc ctcaacatca tagccgggaa tcgtcagaaa tacctgcatc
     8701 gtcattcccg cgcaggcggg aatccagacc tgtcggtgcg gaaacttatc gggtaaaacg
     8761 gtttctggag atttttcgtc ctggattccc actttcgtgg gaatgacgga atgtaggttc
     8821 gtgggaatga cgtggtgcag gtttccgtac ggatggattc gtcattcccg cgcaggcggg
     8881 aatccaattc attcggtttc agccgtttcc gataaatcac tgtaacgtta agttcccgga
     8941 ttcccacttt cgtgggaatg acggcgtaaa ggtttctgct ttttaagttt taggtaacta
     9001 atgagt
//
LOCUS       DAXIDM010000080         8723 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000080 DAXIDM010000000
VERSION     DAXIDM010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8723
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.080"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(188..1084)
                     /gene="argB"
                     /locus_tag="ACFOAE_001538"
     CDS             complement(188..1084)
                     /gene="argB"
                     /locus_tag="ACFOAE_001538"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HFC6885000.1"
                     /translation="MESENIISAADKARILAEALPYIRRFSGSVAVIKYGGNAMTEPA
                     LKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVGKKGEFVQGMRVTDKEAMDIVE
                     MVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVES
                     IDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAG
                     VMDKTGNLLTKLTPKRIDELIADGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNA
                     LLLEIFTDAGIGSMILGGGEDA"
     gene            1254..2384
                     /locus_tag="ACFOAE_001539"
     CDS             1254..2384
                     /locus_tag="ACFOAE_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M14-type cytosolic carboxypeptidase"
                     /protein_id="HFC6885001.1"
                     /translation="MIKISTRFDAGSVVVKDLTDPSNIRLALRPDNASDFAQWFYFRL
                     QGAAYQNCIMHFENAAEAAYPKGWEGYQACASYDRRNWFRVPTSYENGVLTVNHTPLS
                     NSVYYAYFEPYSEEQHLNLLGDAQGSGLCRIDDLGSTVQGRDINLLTIGNQVESDLKI
                     WITARQHPGETMAEWFVEGLLGRLLDPQDATARTLLDRATFYIVPNMNPDGSALGNLR
                     TNAAGANLNREWENPTVEKSPEVFFVREKMLETGVDLFLDIHGDEGLPFIFVAGTEGV
                     PNYNPRISALETQFKTALLNASPDFQDEYGYEKDAPGQANMTLATNWVGNRFNCLAYT
                     LEMPFKDNANLPDDDFGWNGQRSLRLGEAALSAILNIIGDLR"
     gene            2455..3306
                     /gene="lgt"
                     /locus_tag="ACFOAE_001540"
     CDS             2455..3306
                     /gene="lgt"
                     /locus_tag="ACFOAE_001540"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFC6885002.1"
                     /translation="MITHPQFDPVLISIGPLAVRWYALSYILGFILFTFLGRRRIAQG
                     LSVFTKESLDDFLTWGILGVILGGRLGYVLFYKFSDYLAHPLDIFKVWEGGMSFHGGF
                     LGVVIAIWLFGRKHGIGFLKLMDTVAPLVPLGLASGRIGNFINGELWGRVTDINAFWA
                     MGFPQARYEDAEAAAHNPLWAEWLQQYGMLPRHPSQLYQFALEGICLFAVVWLFSKKQ
                     RPTGQVASLFLGGYGIFRFIAEFARQPDDYLGLLTLGLSMGQWLSVPMIVLGIVGFVR
                     FGMKKQH"
     gene            complement(3389..4051)
                     /locus_tag="ACFOAE_001541"
     CDS             complement(3389..4051)
                     /locus_tag="ACFOAE_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein"
                     /protein_id="HFC6885003.1"
                     /translation="MDSRKFTEASKRRLSELLDAKSEQGNTMRCDEVQGFMTALLSGP
                     DKLTPLDWLPEVLGDESQFTAAERSEIERLVLAMAMETTAAMSDKKLPDLWLYENEDG
                     GSDFYTWCNAYLYGLDIVPTDWFEAADDEEFEELFYPIMALGGIYDEEENGAIRLQFT
                     EGELAELESELPYALADIYRYWQAVINKPQTVRREGEKTGRNDPCPCGSGRKYKACCG
                     KN"
     gene            4085..4192
                     /locus_tag="ACFOAE_001542"
                     /pseudo
     CDS             4085..4192
                     /locus_tag="ACFOAE_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(4251..6044)
                     /locus_tag="ACFOAE_001543"
     CDS             complement(4251..6044)
                     /locus_tag="ACFOAE_001543"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HFC6885004.1"
                     /translation="MQLDIDRLVAYFGGVNALAEALKQHDPENAATTAAIYKWRTRGS
                     LPLAQLQKLTALAEAQGRPLDLNAFLQKNESLERTEMTQANRVIIFDTTLRDGEQSPG
                     AAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAVNAIAKTITKSTVCSLSRAIE
                     RDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQVIEAAVKAVKIAREYTDDV
                     EFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPYKTEEFFRELIAKTPNG
                     GKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGNASVEEIVMALKVRH
                     DLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESGIHQDGVLKHRET
                     YEIMSAESVGWSANRLSLGKLSGRNAFKTKLADLGIELESEEALNAAFARFKELADKK
                     REIFDEDLHALVSDEMGNMNTESYKFISQKISTETGEEPRADIVFSIKGEEKRASATG
                     SGPVDAIFKAIESVAQSGATLQIYSVNAVTQGTESQGETSVRLARGNRVVNGQGADTD
                     VLVATAKAYLSALSKLEFSAAKPKAQGSGTI"
     gene            6290..7399
                     /gene="proB"
                     /locus_tag="ACFOAE_001544"
     CDS             6290..7399
                     /gene="proB"
                     /locus_tag="ACFOAE_001544"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFC6885005.1"
                     /translation="MKYKRIVFKVGTSSITHSDGSLSRGKIQTITRQLAALHHAGHEL
                     VLVSSGAVAAGFGALGFKKRPVKIADKQASAAVGQGLLMEEYTANLSSDGIVSAQILL
                     SRADFADKRRYQNAGGALSVLLQRRAVPIINENDTVSVEELKIGDNDTLSAQVAAMIQ
                     ADLLVLLTDIDGLYTGNPNSNPDAVRLDKIEHINHEIIEMAGGSGSANGTGGMLTKIK
                     AATIAAESGVPVYICSSLKPDALAEAAEHQADGSFFVPRAKGLRTQKQWLAFYSESRG
                     SVYVDEGAEHALSEQGKSLLMSGIAGIEGHFSRMDTVTVYSKATKQPLGKGRVLFGSA
                     AAEDLLKSRKAKGVFIHRDDWISITPEIRLLLTEF"
     gene            7412..8674
                     /locus_tag="ACFOAE_001545"
     CDS             7412..8674
                     /locus_tag="ACFOAE_001545"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFC6885006.1"
                     /translation="MSNTQKQLALAKAAKKSVNTADTEEKNRALLAMADSLEAAAADI
                     LAANRQDLEAAAGNIPESMTDRLLLDGKRICAMADGIRAVAALPDPVGEILETSTLPN
                     GLEIVKKRVAMGVIGIIYESRPNVTSDAAALALKSGSAVVLRSGKDAFQSARAIVAAL
                     KTGLAQTRIDPDALQLIEDTGREGSYEMMRAKDYLDLLIPRGGAGLIRAVVENAVVPV
                     IETGTGIVHIYIDKDADWDKALRIVYNAKTSRPSVCNSMEVLLVHEDIAADFLPKLER
                     LLVRDRIEAGLPPVRFRLDPQAARHIGGEAAGADDFDTEFLDYILAVKTVASVEEAVG
                     HIETHGTHHSDGIVTENRHAADYFTTHIDSAAVYINASTRFTDGGEFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYIVQGTGQVRE"
BASE COUNT         1975 a         2466 c         2274 g         2008 t
ORIGIN      
        1 agaatttatc ccaaacaacc ggatttcaaa aaaaccagat tcccgccttc gcgggaatga
       61 cggattttag gtttctgttt tggtttctgt tttcgcggga ataacaactt agaaattgcc
      121 cgaaacccca aaaacagaaa ccggacaaac gggttttccg ccaaagccgg cattttccga
      181 ctttgcttca ggcatcttcc ccaccgccca aaatcatcga accgataccg gcatcggtaa
      241 agatttccag caaaagcgcg ttgggcaccc tgccgtcgat gatgtgcgtg gctttcacgc
      301 cgttgacggc ggcttcgacc gcagaagcga ttttcggcag cataccgcca tacagcgtgc
      361 cgtcggcaat cagttcatca atccgtttcg gcgtgagttt ggtcagcaga ttgcccgttt
      421 tgtccatcac accggcgata ttcgtcatca tcaaaagttt ttcggcgttc aattcttccg
      481 ccaatttgcc tgccaccaaa tcggcgttga tgttgaacgc ttcgcctttt tcacctacgc
      541 cgacgggggc gacgacggga atgcagccgc gttctatcag ccctttaacc aaaccggtat
      601 cgatgctttc caccgtaccg acctgtccga tgtccacgcc attctgttcg ggcgtatcga
      661 tcaaaagttt cttcgcctta atgaaatgat cgtcgcgtcc gctcacgccg accgcgtgtc
      721 cgccatatgt gttaatcatc gacacgattt ctttattgac atgcccgccc aacaccattt
      781 cgacaatatc catcgcctct ttgtcggtaa cgcgcattcc ttggacaaac tcaccctttt
      841 tgccgacttt ttcaagcatc gcattgatct gcggcccgcc gccgtgaacg atgacgggat
      901 gaatgccgac cagcttcagc agcacgacat cgcgggcaaa cccttctttc aaggcaggtt
      961 cggtcatcgc gttgccgccg tacttgatga cggcgaccga accggaaaac cggcggatgt
     1021 aaggcagcgc ttcggcaagg atacgcgctt tgtcggcggc ggaaataatg ttttcagact
     1081 ccataacggc tccctattgt tgacaatttc ggcttatgtt aacgccaaac gccgtctgaa
     1141 acaatcttca gacggcatct ggcagacctt cgggcaggtt gaagccttgc gatacgggcg
     1201 gtaaaatcgc ggtttatccg gttcgagaaa ccggcgacag caaggacttt cccatgatta
     1261 aaatcagcac ccgcttcgat gccggctcgg tcgtcgtcaa agacctgacc gacccttcca
     1321 acatccgcct cgccctgcgt cccgacaacg cctccgattt tgcacaatgg ttctacttcc
     1381 ggctgcaagg cgcggcatat caaaactgca tcatgcattt tgaaaacgcg gcagaagccg
     1441 cctacccgaa aggctgggaa ggctatcagg cgtgtgcctc atacgaccgc cgcaactggt
     1501 tccgcgtacc gacttcctac gaaaacggcg tactgaccgt caatcatacg ccgctgtcca
     1561 acagcgtgta ttacgcctat ttcgaacctt actccgaaga acagcattta aacctcctcg
     1621 gcgacgcgca aggcagcggc ctgtgccgca tcgacgactt gggcagcacc gtgcaaggcc
     1681 gcgacatcaa tctgctgacc atcggcaatc aggtcgaaag cgatctgaaa atctggatta
     1741 ccgcccgcca gcatccgggc gaaaccatgg cggaatggtt tgtcgagggg ctgctcggca
     1801 ggctgctcga ccctcaggat gcaaccgcgc gcaccctgct cgatcgcgcc acgttctata
     1861 tcgtccccaa catgaacccc gacggttcgg cactgggcaa ccttcgtacc aacgccgccg
     1921 gtgcgaacct caaccgcgaa tgggaaaatc cgactgtgga aaaaagcccg gaagtgttct
     1981 tcgtgcgcga aaaaatgctg gaaaccggcg tggatttgtt cttggacatc cacggcgacg
     2041 aagggctgcc ctttatcttt gttgcaggaa ctgaaggcgt gccaaactac aatccgcgca
     2101 tttccgcgtt ggaaacacag ttcaaaaccg cccttttgaa cgccagcccc gatttccaag
     2161 acgaatacgg ttacgaaaaa gatgcgcccg gtcaggcaaa catgaccttg gcaacaaact
     2221 gggtcggcaa ccgtttcaac tgccttgcct atacgttgga aatgccgttc aaagacaatg
     2281 ccaacctgcc cgacgacgat ttcggatgga acggtcaacg gtcgttgcgc ttgggcgaag
     2341 ccgcgttgtc cgccatcctc aacatcatcg gcgatttgcg ctgaaaccct tattgcagaa
     2401 atgccgtctg aagcatcatg cctttcagac ggcatttgaa aacgaaagcc cgttatgatt
     2461 acccatcccc aattcgaccc cgtccttatc agtatcggcc cgcttgccgt ccgctggtat
     2521 gccctaagct acatcctcgg atttattctt tttacctttc tcggcagaag gcgcatcgcg
     2581 caaggcttgt ccgtttttac caaagaatcg ctcgacgact tcctgacatg gggcattttg
     2641 ggcgtaattt tgggcgggcg tttgggttac gtcctgtttt acaagttttc cgactacctc
     2701 gcccatccgc ttgatatttt caaggtatgg gaaggcggaa tgtcgttcca cggcggcttt
     2761 ttgggtgtag ttattgccat atggttgttc ggccgcaaac acggcatcgg cttcctcaaa
     2821 ctgatggaca cggtcgcacc gctcgttccg ctgggtctcg cttcgggacg tatcggcaac
     2881 ttcatcaacg gcgaactttg gggacgcgtt accgacatca acgcattttg ggcaatgggc
     2941 ttcccgcagg cgcgttacga agatgccgaa gccgccgcgc acaatccgct ttgggcagaa
     3001 tggctgcaac aatacggtat gctgccgcgt catccctcgc agctttatca gtttgcactt
     3061 gaaggcatct gcctgttcgc cgtcgtttgg ctgttctcta aaaaacagcg gccgaccgga
     3121 caagtcgcct cgctcttcct cggcggctac ggcatattcc gcttcattgc cgaattcgca
     3181 cgccaacccg acgactatct cgggctgctg accttggggc tgtcgatggg gcaatggttg
     3241 agcgtcccga tgattgtttt gggtatcgtc ggctttgtcc ggttcggcat gaaaaaacag
     3301 cactgaccgc ctgtgaaaaa taccgtctga aacatggaaa tccggtttca gacggcattt
     3361 ttacgtttgg ttcatggaaa caaacgcttc aattcttacc gcaacacgcc ttgtattttc
     3421 tgccgctgcc gcacggacag ggatcgttcc tgcctgtttt ttcgccttcc ctgcggacgg
     3481 tttgcggttt gttgatgact gcctgccagt agcggtagat atccgccaat gcataaggca
     3541 actcggattc cagttccgcc agctcgcctt ctgtgaattg cagacggata gcgccgtttt
     3601 cctcttcgtc gtaaataccg cccaatgcca tgatgggata aaacaactct tcaaattctt
     3661 catcatcggc ggcttcaaac caatcggtcg gcacaatatc caagccgtaa agataagcat
     3721 tgcaccatgt gtaaaaatcg ctgccgccgt cttcgttttc atacagccac aaatcgggca
     3781 gttttttatc cgacatcgcg gcggttgttt ccatcgccat tgccaaaacc agccgttcga
     3841 tttcggaacg ttcggcggcg gtaaattgcg attcgtcgcc caacacttcg ggcagccagt
     3901 cgagcggtgt caatttgtcc ggcccgctca acagcgccgt cataaaacct tgaacctcgt
     3961 cgcaacgcat cgtgttgcct tgttcgcttt tggcatccaa caattcgctc aaccgccgtt
     4021 tggatgcttc ggtaaatttt cgggaatcca tcattttcct tttcaaatgg gttttgcgcc
     4081 ctattatagt ggattaaatt taaatcagga caaggcgacg aagccgcaga cagtacaaat
     4141 agtacggcaa ggcgaggcaa cgccgtactg gtttaaattt aatccactat atcgccgcaa
     4201 tgccgtctga agccttttta tgcttcagac ggcatcgtct gttttcacgc tcaaatcgta
     4261 ccgctgcctt gcgctttcgg tttggcggca ctaaattcca gtttgctcaa agcggaaagg
     4321 taggctttgg cagtggcaac caaaacgtcg gtatccgcgc cctgaccgtt gacgacgcgg
     4381 ttgccgcgtg ccagacggac gctggtttcg ccttggcttt ccgtaccttg cgtgacggca
     4441 ttgacggaat aaatctgcaa agtcgcgccg ctttgcgcca cgctttcaat cgctttgaaa
     4501 attgcatcaa ccgggccgga accggttgcg gaagcgcgtt tttcttcgcc tttgatgctg
     4561 aacacgatgt cggcgcgcgg ctcttcgccg gtttcggtac tgattttttg ggaaatgaat
     4621 ttgtagcttt cggtattcat attgcccatt tcgtccgaca ccagcgcgtg caggtcttca
     4681 tcgaagattt cgcgtttttt gtcggcgagt tctttgaagc gtgcaaatgc cgcgttcagt
     4741 gcctcttcgc tttccaactc gatgcccaaa tccgccagct tggttttgaa ggcgttgcgg
     4801 ccggacaatt tgcccaagct caatcggtta gccgaccaac cgaccgattc ggcagacata
     4861 atctcgtaag tttcgcggtg tttcagcacc ccatcctgat ggatgcccga ttcatgcgaa
     4921 aaggcattgg caccgacaat ggctttgttg ggctgcacgg gatagcccgt aatggtggac
     4981 accagtttgg acgaaggcac gatttgcgtg gtatcgatgc cggtttccaa gccgaacaag
     5041 tcgtggcgca ctttcaacgc catcacgatt tcttcaaccg aagcattgcc tgcacgttcg
     5101 cccaagccgt tgacagtaca ttccacctga cgcgcgccgc cttttaatgc ggcaagcgaa
     5161 ttggcaaccg ccaagcccaa atcattgtgg cagtgtgccg accaaacgac tttgccgccg
     5221 ttgggcgttt tggcaatcag ttcgcggaaa aattcttcgg ttttgtacgg gattgaatag
     5281 ccgacggtat cgggaatatt gatggtggtc gcgcccgctt caatcaccgc gccgcagatt
     5341 tcggcaagga aatcgatttc cgaacgcaac gcgtcttcgc aggaaaattc cacatcgtcg
     5401 gtgtattcac gagcgatttt caccgctttg accgccgcct caatcacctg cttcggcttc
     5461 atcttcaatt tgtactccat atggatgggg ctggtggcga tgaaggtgtg gatgcgtttt
     5521 ttcggcgcgg gcgcaacggc ctcacccgcc tgacggatgt cccgctcgat ggcgcgggac
     5581 aatgaacaga ccgttgattt ggtaatggtt ttcgcaatcg cattgaccgc ctcgaaatcg
     5641 cccgggctgg cagcggcaaa acccgcttcg atgatgtcca cacccaattt ttccagctgg
     5701 cgggcgacgc ggattttttc ctctttggtc atagcggcgc cgggcgattg ttcgccgtcg
     5761 cgcagggtgg tgtcgaaaat gataacgcgg ttggcctgtg tcatttctgt tctctccaga
     5821 gattcgtttt tttgtaaaaa agcattcaaa tccagcggtc tgccttgcgc ttccgccaac
     5881 gcggtcagct tttgcagttg cgccagaggc agcgacccgc gcgtgcgcca tttatagatg
     5941 gcggcggtcg tcgcggcatt ttcgggatcg tgctgtttca acgcttcggc aagcgcgttc
     6001 acgccgccga aataagcaac caagcggtct atatctaatt gcatggtagt ccttgtctaa
     6061 aataaatcag cctacagcag aaatatggac aggattatac gcattttgga caaaacggca
     6121 atataaattt gaaaaatctc aataagccgc catagatttt attaatttta tacattttgt
     6181 ccattttatt gcagacgcgg cgtgattgtt gacaattgcg gcagaacagg gcaaattcgg
     6241 cggcacaagg cggcaaacga gacaggacaa accaacaagg acggaaacaa tgaaatacaa
     6301 aagaatcgta tttaaagtcg gcacatcttc gattacccat tcggacggca gtctctcgcg
     6361 cggcaaaatc caaaccatca cccgccagct tgccgcattg catcatgcgg gacacgagct
     6421 ggtcttggtg tcttccggcg cggttgcggc agggttcggt gcgctgggtt tcaaaaaacg
     6481 tccggtcaaa atcgccgaca aacaggcttc cgccgccgtc gggcaggggc tgctgatgga
     6541 agaatatacg gcaaacctgt cttcagacgg catcgtgtcc gcacaaatcc tgctcagccg
     6601 cgccgacttt gccgacaaac gccgctacca aaatgccggc ggcgcacttt ccgtgctgct
     6661 gcaacgccgc gccgtcccca tcatcaatga aaacgatacg gtttcggttg aggaattgaa
     6721 aatcggcgac aacgacacat tgagtgcgca agtggcggcg atgatacagg cagacctctt
     6781 ggtgctgctg accgacatag acggtcttta cacgggcaac ccgaacagca atcccgatgc
     6841 cgtacggctg gacaaaatcg aacacatcaa ccatgaaatc atcgaaatgg cgggcggatc
     6901 gggttcggca aacggcacgg gcggtatgct gaccaaaatc aaagcggcaa ccatcgccgc
     6961 cgaatccggc gtaccggtgt atatctgttc ctcgctcaaa cccgatgcac ttgccgaagc
     7021 tgccgaacat caggcggacg gctcgttttt cgtcccccgt gccaaaggtt tgcggacgca
     7081 gaagcaatgg ctggcgttct attccgaaag ccggggcagc gtttatgtgg acgaaggtgc
     7141 ggaacacgct ttgtccgaac aggggaaaag cctgctgatg tcgggcattg ccggaatcga
     7201 agggcatttt tcccgtatgg acaccgtaac cgtgtacagc aaggcaacca aacagcccct
     7261 gggcaaaggg cgcgtcctgt tcggttctgc cgccgccgaa gacctgctca aatcgcgtaa
     7321 ggcgaaaggc gtgttcatcc atcgggacga ctggatttcc atcacgcccg aaatacgcct
     7381 gcttctgacc gaattttaga aaaggaaacc catgtcaaac acacaaaaac agcttgccct
     7441 tgccaaagcg gcaaaaaaat ccgtcaacac ggcggatacg gaagaaaaaa accgcgcgct
     7501 gcttgctatg gcggacagtc tggaagcggc ggcggcagat attttggcgg caaaccgtca
     7561 agacttggaa gccgcggcag gcaacattcc cgaaagcatg accgaccgcc ttttgttgga
     7621 cggcaaacgc atttgcgcga tggcggacgg catcagggcg gttgccgcgc tgcccgaccc
     7681 cgtgggcgaa atactggaaa cctcgacttt gcccaacggc ttggaaatcg tcaaaaagcg
     7741 cgtggcgatg ggcgttatcg gcattattta cgaaagccgc ccgaacgtta cgtccgatgc
     7801 ggcggctttg gcactgaaaa gcggcagcgc ggtcgtactc cgcagcggca aagatgcatt
     7861 ccaatccgca cgcgccatcg ttgccgccct gaaaacgggg ttggcacaaa cccgcatcga
     7921 ccccgacgcg ctccagttga ttgaagacac cgggcgtgag ggcagttacg aaatgatgag
     7981 ggcgaaagat tatctagacc tgctgattcc gcgcggcggg gcggggctga tacgggcggt
     8041 ggttgaaaat gccgtcgtgc cggtcattga aacgggaacg ggcatcgtcc acatttatat
     8101 cgacaaggac gcggattggg acaaggcgct ccgtatcgtg tacaacgcca aaaccagccg
     8161 tccgtccgtg tgcaactcga tggaagtgct gctggtgcat gaagacattg ctgccgactt
     8221 cctgcccaag ctcgaacggc tgttggttcg cgaccgtata gaagccggac tgccgcccgt
     8281 ccgcttccgt ttggatccgc aggcggcgcg gcatatcggc ggcgaagcgg cgggtgcaga
     8341 cgatttcgat accgagtttt tagactacat cctcgccgtg aaaaccgtcg cttcggtcga
     8401 agaggcggtc gggcacatcg aaacgcacgg cacgcaccat tcagacggca tcgttaccga
     8461 aaaccgccac gctgcggact atttcacgac ccatatcgat tctgccgccg tgtatatcaa
     8521 cgcgtccacg cgctttaccg acggcggcga attcggcttg ggttgcgaaa tgggcatctc
     8581 cacgcaaaaa ctccacgccc ggggcccgat gggtttaaaa gagctgacga gttacaaata
     8641 catcgtacaa ggcacgggac aggttaggga ataatccgaa ttcaaacgtc tgatatagtg
     8701 gattaacttt aaaccgatac ggc
//
LOCUS       DAXIDM010000081         8595 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000081 DAXIDM010000000
VERSION     DAXIDM010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8595
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.081"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(249..3101)
                     /gene="gcvP"
                     /locus_tag="ACFOAE_001546"
     CDS             complement(249..3101)
                     /gene="gcvP"
                     /locus_tag="ACFOAE_001546"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004375 - glycine dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_process: GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HFC6885007.1"
                     /translation="MKLSELFNPNEFAARHLSFGDGAALLEVLGEKSMDDFVGNTVPQ
                     SIRMPSELDLPEALTEADALAKLKGIASKNVINKSYIGLGYYPTRVPNVILRNVLENP
                     GWYTAYTPYQAEIAQGRLEALLNFQQVCIDLTGFPVAGASLLDEATAAAEAMAMAHRV
                     GKVKSERFFVDARVYPQTLDVMKTRAKYFGFELVVGDFAQAEEGEYFGALFQYVGKDG
                     DVQDLQDVIGRLKAKGTIVAVAADIMSLVLLKSPAELGADIALGNTQRFGVPMGFGGP
                     HAAYFAFKDEFKRSAPGRIIGVSKDASGKPALRMALSTREQHIRREKATSNICTAQAL
                     LANLAGMYAVYHGPEGVKRIANRIHALASAFADALVSDGLNVVHKVFFDTVTVDFGSK
                     EQADQVFAAALESGYNLRRVSDTQVAAAFHETSTREDLVDLYRAFTGKDTFAFADDVK
                     GRLNAELLRQNDILQHPVFNSYHTEHEMLRYLKKLEDRDLAMNRSMISLGSCTMKLNA
                     TAEMLPITWAEFSDIHPYAPEAQTAGYRELLADMENSLKAITGFDAISFQPNSGAQGE
                     YSGMLAIRRYQEANGEGHRNICLIPKSAHGTNPATAAMLGLKVVVVDTDEHGNVNIDD
                     LKAKAEQHRDALSAIMITYPSTHGVYEEGIRDICRIVHENGGQVYMDGANLNAQIGIM
                     QPAEVGADVLHMNLHKTFCIPHGGGGPGMGPIGLKAHLAPFAPGHALTDTHSASADQT
                     AVAAAAFGSASILPITWMYLTMMGKQGMEQATRWALLNANYVAKRLSEDYPILYTGKN
                     GRVAHECIVDLRPLKAESGITETDIAKRLMDYGFHAPTVSFPVAGTLMIEPTESESKA
                     ELDRFIAALKQIKQEVLKVGRGEWPKDDNPLVNAPHTAADITGDWARPYSREEAVFPL
                     PFVREHKFWPFVNRVDDVYGDRNLVCSCPPMENYED"
     gene            complement(3132..3491)
                     /locus_tag="ACFOAE_001547"
     CDS             complement(3132..3491)
                     /locus_tag="ACFOAE_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885008.1"
                     /translation="MTDRPSLLWIKPGQAEIMEYCEPEEASDPYATYRCANLMAVLPL
                     FVVILVLLNIVFPLPAHPLAWLVPAGFMVLVGGFPLSLPLAVLLVLTCCILARCPPLS
                     RLLCYPCPNHPMSKNSA"
     gene            3490..3669
                     /locus_tag="ACFOAE_001548"
     CDS             3490..3669
                     /locus_tag="ACFOAE_001548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HFC6885009.1"
                     /translation="MPSEPAGRLFQKMPYRCNFMRLYGVGFALQTAYASRSSLVSQSV
                     HDYINNLGADKPLFI"
     gene            complement(3662..4303)
                     /locus_tag="ACFOAE_001549"
     CDS             complement(3662..4303)
                     /locus_tag="ACFOAE_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylesterase"
                     /protein_id="HFC6885010.1"
                     /translation="MPSEKPMNRRTFLLGAGALLLTACGRKSARTHAKIPEGSTVLAL
                     GDSLTFGYGANPGESYPAQLQKLTGWNIVNGGVSGDTSAQALSRLPALLARKPKLVIV
                     GIGGNDFLRKVPKEQTRANIAKIIETVQKENIPAVLVGVPHITLGALFGHLSDHPLYE
                     DLSEEYGIPLFGGAWAEILGDNNLKSDQIHANGKGYRKFAEDLNQFLRKQGFR"
     gene            complement(4293..4844)
                     /locus_tag="ACFOAE_001550"
     CDS             complement(4293..4844)
                     /locus_tag="ACFOAE_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFC6885011.1"
                     /translation="MNYCEFAASLPENTDNPNKHYHDTQYGFPIDSDNGLFERLVLEI
                     NQAGLNWTLMLKKQQAFQTAFKGFDIDTVAAFGEADIERLLADAGIVRNRLKIDAAIF
                     NARQIQALQQEYGSFKNWLDTHHPRSKDEWVKLFKKHFKFVGGEIVGEFLMSTGYLKG
                     AHAESCPVYRETLKYHPKWLDAV"
     gene            complement(4848..5366)
                     /locus_tag="ACFOAE_001551"
     CDS             complement(4848..5366)
                     /locus_tag="ACFOAE_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HFC6885012.1"
                     /translation="MRLFPIAAALTLAACGTVQSTQYFVLPDSRYIRPATQGGETAVE
                     VRLAEPLKRGGLVYQTDPYRLNTAQNHVWADTLDDMLEAALSNAFNRLDNTRIFVPAS
                     RSGSTEKWTVYIDAFQGSYTGKTLISGYAVLPDGTNRPFHIETEQQGDGYAAMTAALE
                     QGLKQAAQQMVE"
     gene            complement(5366..7027)
                     /gene="pqiB"
                     /locus_tag="ACFOAE_001552"
     CDS             complement(5366..7027)
                     /gene="pqiB"
                     /locus_tag="ACFOAE_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HFC6885013.1"
                     /translation="MTDNSPPPNGHAQARVRKNNTLLSAVWLVPLIALIAGGWLWIKE
                     IRNRGPVVTLLMDSAEGIEVNNTVIKVLSIDVGRVTRIKLRDDQKGVEVTAQLNADVS
                     GLIRSDTQFWVVKPRIDQSGVTGLGTLLSGSYIAFTPGKSDEAKDVFQVQDIPPVTAI
                     GQSGLRLNLIGKNDRILNVNSPVLYENFMVGQIESAHFDPSDQSVHYTIFIQSPNDKL
                     IHSASRFWLESGINIETTGSGIKLNSAPLPALLSGAISFDSPKTKNSKNVKSEDSFTL
                     YDSRSEVANLPDDRSLYYTAFFKQSVRGLTVGSPVEYKGLNVGVVSDVPYFDRNDSLH
                     LFENGWIPVRIRIEPSRLEINADEQSKEHWKQQFQTALNKGLTATISSNNLLTGSKMI
                     ELNDQPSSSPKLRPHTVYAGDTVIATQGGGLDDLQAKVVDLLDKFDKLPLDKTVAELN
                     GSLAELKSTLKSANAALSSIDKLVGKPQTQNIPNELNQTLKELRTTLQGVSPQSPIYG
                     DVQNTLQSLDKTLKDVQPVINTLKEKPNALIFNSSSKDPIPKGSR"
     gene            complement(7020..8354)
                     /locus_tag="ACFOAE_001553"
     CDS             complement(7020..8354)
                     /locus_tag="ACFOAE_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqiA/YebS family transporter subunit"
                     /protein_id="HFC6885014.1"
                     /translation="MPPLIFATFPMKPFAENIPHSLRGNCRDEALPPHTVDCPECGCR
                     ADVPRLDRGEAAFCPRCGYKLFRVGRHPFSAPPAYAAASLILMAFAYGMTYIEVGIPG
                     AASVLSLPEMMRLMVFQDYGFLAEVMFVLTFGAPVLFLLLCLYVYAALIRKQAYPALR
                     LATRVMVRLRQAMMVDVFFVSTLVAYIKLSSVAEVRFGSAFYLMFALSVMLIRTSVSV
                     PQHWVYFQIGRLTGDNAVQTASEGKTCCSRCLYFRDSAESPCGVCGAELYRRRPKSLS
                     ISSAFLTAAVILYFPANILPIMISSNPAATEVNTILNGIAYMWDEGDRLIAAVIFSAS
                     ILVPVLKIAAMSVLIASARFALPTGAKKLSHLYRITEAVGRWSMIDIFVIIILMCSFH
                     TYAARVIPGSAAVYFCLVVILTMLSAYYFDPRLLWDKRASDGIAFNETEKHD"
BASE COUNT         1923 a         2196 c         2430 g         2046 t
ORIGIN      
        1 tccactatat ttgtttgtcc gtgtggaaat gacatcaaag ggtgtgaata ggcttttcat
       61 ctttgaaatc tgtttgcacg atcggatgaa taaaaagtag gatgataaaa aagctgatgt
      121 atggatactg gtttaactca tttgttttaa agttatagtc gagatacgtg tattggtgca
      181 actggtttgc cgttgatgaa aatgccgtct gaaaatgttt cagacggcat tttttaagat
      241 atcaacagtc agtcttcata attttccatc ggtgggcagc tgcacacgag attgcggtcg
      301 ccgtacacgt cgtccacgcg gttgacgaag ggccaaaact tgtgttcgcg cacgaagggc
      361 agcgggaaga cggcttcttc gcgggaatac gggcgcgccc agtcgccggt tatatctgcg
      421 gcggtgtgcg gcgcgttgac cagtgggttg tcgtctttcg gccattcgcc gcgcccgact
      481 ttcagcactt cctgtttgat ttgtttcagg gcggcgatga agcggtcgag ttcggctttg
      541 ctttcgctct cggtcggctc gatcatcagc gtaccggcaa cggggaagga aaccgtcggg
      601 gcgtggaagc cgtagtccat caggcgtttg gcgatgtcgg tttcggtaat gccgctttcg
      661 gctttgagcg gacgcaaatc gacgatacat tcgtgcgcga cgcggccgtt tttgcctgta
      721 tacagaatcg gatagtcttc gctcaggcgt ttggcaacgt agttggcgtt gagcaatgcc
      781 cagcgtgtcg cctgttccat gccttgtttg cccatcatgg tcagatacat ccaagtaatc
      841 ggcagtatgg acgcagaacc gaaggccgca gcagcaacgg cggtttggtc ggcactggcg
      901 ctgtgggtgt cggtcaaagc gtgtcccggt gcgaacggag ccagatgggc tttcaagcca
      961 atcggaccca tgcccggacc gccgccgccg tgagggatac agaaggtttt gtgcaggttc
     1021 atgtgcaaca cgtccgcgcc gacttcggca ggctgcatga tgccgatttg ggcgttgagg
     1081 ttggcgccgt ccatgtaaac ctgtccgccg ttttcatgga cgatgcggca gatgtcgcgg
     1141 atgccttctt cgtacacgcc gtgggtggac ggataggtaa tcatgatggc ggacaaagcg
     1201 tcgcggtgtt gctcggcttt ggctttcaaa tcgtcgatgt tgacgttgcc gtgttcgtcg
     1261 gtatcgacga cgacgacttt caaaccgagc atggcggcgg tggcggggtt ggtgccgtgg
     1321 gcggatttgg gaatcagaca gatgttgcgg tgtccctcgc cgttggcttc ctgatagcgg
     1381 cggatggcaa gcataccgct gtattcgccc tgcgcgccgg agttgggctg gaaggaaatc
     1441 gcgtcaaagc cggtgatggc tttcaggctg ttttccatgt cggcaagcaa ttcgcggtag
     1501 ccggcggttt gcgcttcggg agcgtaaggg tggatgtcgg agaactccgc ccaagtaatc
     1561 ggcaacattt ccgcagtggc attgagtttc atggtgcaac tgcccagcga aatcatactg
     1621 cggttcatcg ccaaatcgcg gtcttcgagt tttttcaggt agcgcaacat ttcgtgttcg
     1681 gtgtggtaac tgttgaacac aggatgttgc agaatgtcgt tttgacgcag taattcggcg
     1741 ttcagacggc ctttgacatc atcggcaaat gcgaacgtat ccttgccggt aaacgcgcgg
     1801 tacaaatcaa ccaaatcttc gcgtgtcgaa gtttcatgga aggctgctgc gacttgagta
     1861 tcgctgacgc ggcgcaggtt gtagcccgat tccaaagcag cggcaaacac ttggtctgct
     1921 tgctctttgc tgccgaaatc gacggtaacg gtatcgaaga agaccttatg aaccacattc
     1981 aggccgtctg aaaccagcgc atcggcaaag gcagaagcca gcgcgtgaat gcggttggcg
     2041 atgcgtttca caccttcagg gccgtggtaa acggcgtaca tacccgccaa gttcgccagc
     2101 aatgcctgcg cggtacaaat attggatgtc gctttttcgc ggcggatgtg ttgctcgcgg
     2161 gtggacaacg ccatgcgcaa ggcaggtttg cctgatgcgt ctttggatac gccgatgatg
     2221 cggcccgggg cggaacgttt gaactcgtct ttaaacgcga aataagcggc gtgcggacca
     2281 ccaaagccca taggcacgcc gaagcgttgc gtgttgccca aagcaatatc cgcacctagt
     2341 tcagccggag acttcagcaa aaccaagctc ataatgtcgg ctgcaacggc aacgattgtg
     2401 cctttggctt tcagacggcc gataacgtcc tgcaagtctt gcacatcgcc gtctttgccg
     2461 acgtattgga acagcgcacc gaagtattcg ccttcctccg cttgggcaaa atcaccgacc
     2521 accaattcaa agccgaaata tttggcgcgg gttttcatca cgtccaaagt ttgcggatac
     2581 acgcgcgcat ccacaaagaa acgttcggat ttcactttgc ccacgcggtg cgccatcgcc
     2641 atcgcttcgg cggcggcagt tgcctcatcc agcaaagacg cgcctgccac agggaaaccg
     2701 gtcaaatcga tacacacttg ttggaagttc aacaaagctt ccaaacgacc ctgggcgatt
     2761 tccgcctgat acggcgtgta ggcggtatac cagcccggat tttccaatac gttgcgcaaa
     2821 atcacgttcg gcacgcgggt cgggtaatag cccaagccga tataggattt gttgatcacg
     2881 tttttcgacg caatgccttt caattttgcc aacgcgtccg cttcggtcaa cgcttcgggc
     2941 aaatcgagtt cagacggcat acggatgctt tgcggcacgg tattgccgac aaaatcgtcc
     3001 atgcttttct cgccgagcac ttccaaaagt gcagccccgt cgccaaagct caaatggcgc
     3061 gcggcaaatt cgttcgggtt gaacagttcg gacagtttca tttctactcc ttcgggtttg
     3121 tagggctgcc atcaggcaga atttttagac atcggatgat tcgggcaagg gtagcacaaa
     3181 agacgggata atggcggaca acgcgccaga atgcagcagg tcaggacaag cagcaccgca
     3241 agcggcagcg ataagggaaa gccgccgacc aaaaccatga aacctgcagg caccagccaa
     3301 gctaagggat gcgccggaag cggaaaaaca atattgagca gaaccaaaat cacgacaaac
     3361 agcggcagca ccgccatcag gttggcacac ctgtatgttg cgtacgggtc ggacgcttct
     3421 tcaggttcgc aatattccat gatttcagcc tgtccgggct ttatccacag caggctcgga
     3481 cggtcggtca tgccgtctga accggcaggc cgtctttttc aaaaaatgcc ataccgctgc
     3541 aacttcatgc ggctgtatgg cgtaggtttt gcacttcaga cggcatatgc gtcccgaagc
     3601 agtttggtgt cccagtcggt tcatgattat ataaacaact tgggtgcgga taaacctttg
     3661 tttatctaaa cccctgtttt ctcaaaaatt gattcaaatc ttcggcaaat ttccgatagc
     3721 ctttgccgtt ggcgtggatt tggtcggatt tcagattatt atcgcccaaa atttccgccc
     3781 acgcgccgcc gaacagcgga atgccgtatt cctcggacaa atcctcatac agcggatgat
     3841 cgctcaaatg cccgaacaac gcgcccagtg tgatgtgcgg cacgccgacg aggacggcgg
     3901 ggatgttttc cttctgcacg gtttcgatga ttttcgcgat attggcgcgg gtctgctcct
     3961 tgggaacttt gcgcagaaag tcgttgccgc ctatgccgac aatcacaagc ttgggtttgc
     4021 gtgccaacag cgcgggcagg cgcgacaggg cttgggcgga tgtatcgccc gatacgccgc
     4081 cgttgacaat attccaaccc gtcagttttt gcagttgcgc ggggtaggat tcgccggggt
     4141 ttgcgccgta gccgaaggta agcgaatcgc ccaaggcaag tacggtgctt ccttcgggaa
     4201 ttttggcgtg ggttcgggcg gattttctgc cgcaggcggt aaggagcaac gcgcctgcgc
     4261 cgaggaggaa ggttcttctg ttcattggtt tttcagacgg catcgagcca tttcgggtgg
     4321 tatttcaggg tttcacggta aaccggacag ctttcggcgt gcgcgccttt gaggtagccg
     4381 gtactcatca gaaattcgcc gacgatttcg ccgccgacga atttgaaatg ttttttaaag
     4441 agtttaaccc attcgtcttt gcttcgcgga tggtgcgtgt cgagccagtt cttgaacgag
     4501 ccgtattctt gttgcaacgc ttggatttgc cgtgcattga aaatggcggc atcgattttc
     4561 aggcggttgc ggacaatgcc cgcgtcggca agcagccgct caatatcggc ttcgccaaat
     4621 gcggcaaccg tatcgatgtc gaaaccttta aatgccgtct gaaatgcctg ctgcttcttc
     4681 agcatcagcg tccagtttaa tcctgcctga ttgatttcca acaccagccg ttcaaacagt
     4741 ccgttgtcgc tgtcaatcgg aaaaccgtat tgcgtgtcgt ggtaatgttt gttcgggtta
     4801 tcggtgtttt cgggaagtga ggcggcaaat tcgcaatagt tcacggttta ctcgaccatc
     4861 tgttgcgccg cctgtttcag tccctgttcg agtgcggcgg tcatcgcggc gtagccgtca
     4921 ccctgctgtt cggtttcgat atggaaaggt ctgttcgtac cgtcgggtag gacggcgtag
     4981 ccgctgatga gggttttgcc cgtgtagctg ccttggaatg cgtcgatata gaccgtccat
     5041 ttttcggtac tgccgctgcg tgaggcagga acaaagatgc gtgtgttgtc caaacggttg
     5101 aatgcattgc tcaacgccgc ttcgagcata tcgtccaagg tgtctgccca aacgtggttt
     5161 tgtgcggtgt tgaggcggta ggggtcggtt tgatagacca gtccgccgcg tttgagcggt
     5221 tcggcaagac ggacttcgac ggcggtttcg ccgccttgtg ttgcaggacg gatgtagcgg
     5281 ctgtcgggca acacgaaata ttgtgtgctt tgcacagtac cgcaggcggc aagcgtcagg
     5341 gcggcggcaa tcgggaagag gcgcattatc ggcttccttt cgggatgggg tctttgctgc
     5401 tgctgttgaa aatcagcgcg ttgggttttt ctttcaaagt attaattacg ggttgaacgt
     5461 cttttaaggt tttgtccaaa ctttgcaacg tattttgtac gtcgccgtag ataggcgatt
     5521 gaggcgatac gccttgcagg gttgtgcgca actctttcag ggtttggttc agttcgttcg
     5581 gaatgttttg tgtctgcggt ttgccgacca gtttgtcgat ggagcttagg gcggcattgg
     5641 cagatttgag tgtggatttg agctcggcaa gcgaaccgtt caattcggca accgtcttat
     5701 ctaaaggcag tttgtcgaac ttgtccagca aatccaccac tttcgcctgc aaatcgtcca
     5761 aaccgccgcc ttgtgtagcg atgacggtat cgcctgcata aacggtatgc ggtcgcagct
     5821 tgggcgaaga cgaaggctga tcgttcaact caatcatttt gctgccggtc agcaggttgt
     5881 tgctggagat ggtggcggtc aggcctttgt ttaaagccgt ctgaaattgt tgtttccaat
     5941 gctctttgct ttgttcgtcg gcattgattt ccaaacggga aggctcgatg cggatgcgta
     6001 cgggtatcca gccgttttca aataaatgca ggctgtcgtt gcggtcgaaa taagggacat
     6061 cggaaaccac gccgacattc agccctttgt actcgacggg cgaaccgacg gtcagtccgc
     6121 gcacggattg tttgaaaaac gcggtgtagt acagcgagcg gtcgtcaggc aggttggcga
     6181 cttcgctgcg gctgtcgtaa agcgtgaagc tgtcttcgct tttaacgttt ttactgtttt
     6241 tggttttcgg cgaatcaaat gaaatcgcgc ccgacagcag ggcaggcaga ggggcggaat
     6301 tgagtttgat gccgctgcct gtggtttcga tattgatgcc gctttccagc caaaaacggc
     6361 tggcggaatg aatcagtttg tcgttggggc tttggatgaa gatggtgtaa tgcacgcttt
     6421 ggtcggacgg gtcgaaatgc gcgctttcga tttgcccgac cataaagttt tcatacaaaa
     6481 cagggctgtt gacgttgagg atacggtcgt ttttaccaat caaattcaag cgcagaccgc
     6541 tttgcccgat ggcggtaacg ggcggaatgt cctgcacttg gaacacgtct tttgcctcgt
     6601 cgcttttgcc gggtgtaaag gcgatgtacg aacccgaaag cagcgtaccc aaaccggtta
     6661 cgccgctttg gtcgatacgc ggcttgacca cccaaaactg tgtgtcgctg cggatgaggc
     6721 cggatacgtc cgcattgagt tgggcggtta cttccacgcc tttctggtcg tcgcgcagtt
     6781 tgattcgggt aacgcgtccg acatcgatgc tcaatacctt aatgaccgta ttgttgacct
     6841 caatgccttc cgcgctgtcc atcaagagcg taaccacagg ccccctgttg cggatttcct
     6901 taatccacag ccagccaccg gcaatcagcg caatcagcgg gaccagccag acggcggaga
     6961 gcaaggtgtt gtttttgcgg acgcgtgctt gggcgtgtcc gtttggagga gggctgttgt
     7021 cagtcatgtt tttccgtttc gttgaaagca atgccgtctg aagcgcgttt gtcccaaagc
     7081 aggcgcgggt cgaaataata ggcggacagc atcgtcagaa tcacgaccag gcagaaatag
     7141 actgccgcac tgcccggaat gacgcgcgcg gcataagtgt ggaacgaaca catcaaaata
     7201 ataatcacaa aaatatcaat catcgaccag cggccgaccg cttcggtgat gcggtagagg
     7261 tgcgacaatt tctttgcacc cgttggcaaa gcgaagcggg cggacgcaat caaaaccgac
     7321 attgccgcaa tcttcagtac cggcaccaaa atactcgcgc tgaaaataac cgccgcaatc
     7381 agcctgtcgc cctcgtccca catataagcg atgccgttaa ggatggtatt gacctccgtg
     7441 gcggcaggat tggacgaaat cataatcggc aggatattgg cagggaaata caaaataacc
     7501 gccgccgtca gaaacgccga cgaaatactc agacttttcg gccgtcggcg gtacagttcc
     7561 gcaccgcaca cgccgcaggg ggattcggca ctgtcgcgga aatacaggca acggctgcaa
     7621 caggttttac cttccgatgc cgtctgaacc gcattatccc ccgtcagccg cccgatttga
     7681 aaatacaccc aatgctgggg aaccgatacc gaagtccgaa tcagcataac cgacagcgcg
     7741 aacatcagat aaaacgccga tccgaagcga acctctgcca cagacgagag cttgatatac
     7801 gccaccaaag tggaaacaaa aaacacatcc accatcatcg cctgtctcaa gcgcaccatc
     7861 acacgcgttg ccaaacgcag cgcaggatac gcctgtttcc gtatcagcgc ggcatagaca
     7921 tacaggcaca gcagcagaaa cagaaccggc gcgccgaagg tcagcacaaa catcacttcg
     7981 gccaaaaaac cataatcctg aaacaccatc aggcgcatca tctcgggcag cgaaaggacg
     8041 gatgccgcac ccggtatccc gacctcgata tacgtcatac cgtaagcaaa cgccatcaaa
     8101 atcagcgaag ccgccgcata agcgggcggg gcggaaaaag gatgcctgcc caccctgaag
     8161 agcttatagc cgcaacgggg acagaacgcc gcctctcccc tgtccaaccg gggtacatcc
     8221 gcgcggcagc cgcattccgg gcaatctacc gtatgcggcg gcagggcttc gtcgcggcag
     8281 ttgccgcgaa ggctgtgggg gatattttcg gcaaacggct tcatcgggaa agtggcaaat
     8341 ataagtggcg gcattataaa ggaaaaaagg cgatacaccc aatcaggatg caaaaccggc
     8401 aggttcggca gtatgaacaa acccttggtg tccggcaaaa atattttttg agcggctgtc
     8461 cgccgactgc cgaacccatt tgataaaatc ccgattctgt aaagaatagt aaaatacctg
     8521 cttaaaaaca tcacgcaaat gatatttttt ccaaaaatat gtgataataa atttcgttta
     8581 tgattcttta ttatt
//
LOCUS       DAXIDM010000082         8363 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000082 DAXIDM010000000
VERSION     DAXIDM010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8363
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.082"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(129..518)
                     /locus_tag="ACFOAE_001554"
                     /pseudo
     CDS             complement(129..518)
                     /locus_tag="ACFOAE_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(720..1094)
                     /locus_tag="ACFOAE_001555"
                     /pseudo
     CDS             complement(720..1094)
                     /locus_tag="ACFOAE_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805306.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1400..2659)
                     /gene="rho"
                     /locus_tag="ACFOAE_001556"
     CDS             complement(1400..2659)
                     /gene="rho"
                     /locus_tag="ACFOAE_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003823056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFC6885015.1"
                     /translation="MHVSELQTLHISKLLELAEEHGIENANRFRKQDLVFAIVRQMMK
                     KGEGFTCSGTLEILPDGFGFLRSADTSYLAGPDDIYVSPTQIRRFNLHTGDTIEGSVR
                     VPKDNERYFALVRLDTINGDHPEVCRHKILFENLTPLFPTQQLKLERDLKSEENLTGR
                     AIDLISPIGKGQRALLVAPPKSGKTVMLQNIAHAVTANYPEVELIVLLIDERPEEVTE
                     MSRSVRGEVVSSTFDEPAQRHVQVAEMVLEKAKRMVEHKKDVVILLDSITRLARAYNT
                     VVPTSGKILTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALVETGSRMDDVIYEE
                     FKGTGNMELHLDRRMAEKRLFPAININKSGTRREELLVPNDQLQRMWLLRKFLHPMDE
                     IEAAEFLIGKIKASKNNDDFFELMRGK"
     gene            complement(2879..5263)
                     /gene="ppsA"
                     /locus_tag="ACFOAE_001557"
     CDS             complement(2879..5263)
                     /gene="ppsA"
                     /locus_tag="ACFOAE_001557"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008986 - pyruvate, water dikinase
                     activity [Evidence IEA];
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HFC6885016.1"
                     /translation="MADNYVIWFENLRMTDVERVGGKNASLGEMISQLTEKGVRVPGG
                     FATTADAYRAFLAHNGLSERISAALAKLDVEDVAELARVGKEIRQWILDTPFPEQLDA
                     EIEAAWNKMVADAGGADISVAVRSSATAEDLPDASFAGQQETFLNINGLDNVKEAMHH
                     VFASLYNDRAISYRVHKGFEHDIVALSAGVQRMVRSDSGASGVMFTLDTESGYDQVVF
                     VTSSYGLGENVVQGAVNPDEFYVFKPTLKAGKPAILRKTMGSKHIKMIFTDKAEAGKS
                     VTNVDVPEEDRNRFSITDEEITELAHYALTIEKHYGRPMDIEWGRDGLDGKLYILQAR
                     PETVKSQEEGNRNLRRFAINGDKTVLCEGRAIGQKVGQGKVRLIKDASEMDSVEAGDV
                     LVTDMTDPDWEPVMKRASAIVTNRGGRTCHAAIIARELGIPAVVGCGNATELLKNGQE
                     VTVSCAEGDTGFIYAGLLDVQITDVALDNMPKAPVKVMMNVGNPELAFSFANLPSEGI
                     GLARMEFIINRQIGIHPKALLEFDKQDDELKAEITRRIAGYASPVDFYVDKIAEGVAT
                     LAASVYPRKTIVRMSDFKSNEYANLVGGNVYEPHEENPMLGFRGAARYVADNFKDCFA
                     LECKALKRVRDEMGLTNVEIMIPFVRTLGEAEAVVKALKENGLERGKNGLRLIMMCEL
                     PSNAVLAEQFLQYFDGFSIGSNDMTQLTLGLDRDSGLVSESFDERNPAVKVMLHLAIS
                     ACRKQNKYVGICGQGPSDHPDFAKWLVEEGIESVSLNPDTVIETWLYLANELNK"
     gene            5674..6495
                     /locus_tag="ACFOAE_001558"
     CDS             5674..6495
                     /locus_tag="ACFOAE_001558"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFC6885017.1"
                     /translation="MSSPRHVFYISDRTGLTAENIGEALLNQFGNLSFKRHTHPFVDT
                     PEKARAVVEKVNRSRQENGQRPIAFVSVVDDEIRRIIKGADAFQINFFETFLGLLEKE
                     LNTEATASEQGYHSIGNTKRYDARMEAVNFSLNHDDGVSDKNLQEADVILMGVSRSGK
                     TPTCLYLALQYGIRAANYPLIPDDLESADLPRMVKPYRDKLFGLTIQPERLQAIRQER
                     RPNSTYAKIDTCRSEVADAQSMFRRHGIPFANTTDKSVEELAVHILQACKLKRKF"
     gene            complement(6735..7397)
                     /locus_tag="ACFOAE_001559"
     CDS             complement(6735..7397)
                     /locus_tag="ACFOAE_001559"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFC6885018.1"
                     /translation="MIHAVLFDLDGTLADTALDLGGALNTLLARHGLPPKSMDEIRTQ
                     ASHGAAGLLKLGAGITPEHPDYARWRTEYLDEYDSRYAQDTTLFGGVNELIAELDRRG
                     IKWGIITNKPMRFTDKLAPKLGFIIPPAVVVSGDTCGEPKPSVKPMLYACGQIHADPQ
                     HTLYVGDAERDIQAGRNAGMKTVLAEWGYIAPEDDTGSWQADFHIRTPLDLLECLDKI
                     QP"
     gene            complement(7435..8262)
                     /locus_tag="ACFOAE_001560"
     CDS             complement(7435..8262)
                     /locus_tag="ACFOAE_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFC6885019.1"
                     /translation="MKLDIYALLERALLSGDPDEKGRLTDEAFAAVQNADGAEANAPP
                     ADFPRAGRPDKPVLVAPSQLTPRKMNTTEGYAAMLHAIAHIEFNAVNLALDAAYRFRT
                     LPFQFVRDWVKVAKEEVYHFRLMRDRLRAFGFDYGSFEAHNHLWDMAYKTAYDPLLRM
                     ALVPRVLEARGLDVTPGIRAKVAQRGDSETCGVLDIIYRDEVGHVAIGNHWYQHLCRE
                     RGLEPVALFRSLIARYDMFIFRGYVNIEAREKAGFSRFELDMLEDFEQGLKQNKHAV"
BASE COUNT         1798 a         2023 c         2368 g         2174 t
ORIGIN      
        1 ttccctcccg acagccgaaa cccaaacaca ggttttcagt tgttttcgcc ccaaataccg
       61 cctaattcta cccaaatacc cccttaatcc tcaccggacg cccgataatt aggcatccga
      121 gccgcctttt aggcggcagc aggcgcactt agcctgttgg cggctttcaa caggttcaaa
      181 cacatcgcct tcagatggct ttgcgcactc actttaatca gtccgaaata ggctgcccgg
      241 gcatagcgga atttacggtg cagcgtaccg aagctttgtt cgaccacata acgggtcttc
      301 gacaaatatc ggttacgttt ggtttgcgct tccgccagcg gacggttgcg gcaggctttg
      361 cgcataatgc cgtcctgcaa ctgatgttct tccagatgtt gccggttttc cgcactgtca
      421 tagcctttgt cggcatagac ggtcgtacct ttgggcagtc cttccaacaa cggcgacagg
      481 tgtttgcact catgggcatt ggcggaggta tagtggatta acaaaaatca ggacaaggcg
      541 acgaagccgc agacagtaca aacagtacgg aacccattca cttggtgctt cagcacctta
      601 gagaatcgtt ctctttgagc taaggcgagg caccgccgta ctggtttttg ttaatccact
      661 ataaaaattt atggggctgt cctagataac taggataaac tcgattttac taattgtttt
      721 caaatggaaa tttgaacttt tatctcactg ttgttaaaac gtcgttcgta cccctttaaa
      781 tacagctcaa aatgcgcttt gggaatgccg tcaaacttgc gtaaatgacg ttttgcccgg
      841 tttcaaaagt tcccaattcc attgatatgg ttttgtcgtt cagcaaaata actttcatct
      901 gcttctactt tgccgtcaaa catttccaaa tgcggactgt tttgataaat aagtaatcgt
      961 aaacgatgaa aataataggc tgcggtattt ttattaacgc ctactaactc tgctgctgtt
     1021 cttgcagtta cacctgcgac aaacagttca atgagtttat tttgtttata ctggcttaga
     1081 cgactttttc tcataggggc aactctaact taatttgaat ttccctagtt atctaggaca
     1141 gccccaaatt tatacaaaaa tgagcgcggt tcggcgcaac cttgaatcaa gttcccgcat
     1201 cggttttcat tgccggtacg gatgcgttca agccggtttt tcaaaggccg cgctttcggc
     1261 aagcggacac ggacactgcc gacggttgcg ccgttaacgg ggggagggag gagctgcgcc
     1321 gaccgtgtga atgaaagtgc cgtctgaaac ccgattttca ggcttcagac ggcatttcgc
     1381 attaatgcgg gtggcgcgtt tatttgccgc gcatcagttc aaagaaatca tcattgtttt
     1441 tagaggcttt gattttcccg attaaaaatt cggctgcctc gatttcgtcc atcgggtgca
     1501 ggaacttgcg taagagccac atacgttgca actggtcgtt cggcacaagc agctcttcgc
     1561 ggcgcgtgcc ggatttgttg atgttgatgg cggggaagag gcgtttttcc gccatacggc
     1621 ggtcgaggtg caattccata ttgccggtgc ctttgaattc ttcgtaaatc acatcgtcca
     1681 tacggctgcc ggtttcaacc aatgctgtgg caatgatggt cagcgaaccg ccttcttcca
     1741 cgttgcgcgc cgcgccgaag aaacgtttgg gacggtgcag tgcgttggca tcgacaccgc
     1801 cggtcaggat tttgcccgag gtaggcacga cggtattgta ggcgcgggca aggcgggtaa
     1861 tcgaatccag caggatgacc acgtcttttt tgtgttccac catacgcttg gctttttcaa
     1921 gtaccatttc ggcaacttgg acgtggcgtt gcgccggctc gtcaaatgtt gaagaaacca
     1981 cttcacctcg gacggagcgg ctcatttcgg taacttcttc gggacgctcg tcaatcaaga
     2041 ggacgatgag ctcgacttca ggatagtttg cggtaacggc gtgggcaata ttttgcaaca
     2101 tcacggtttt accgcttttg ggcggggcaa ccaagagggc gcgctgacct ttgccgatgg
     2161 gggaaatcag gtcgatggcg cgtccggtca ggttttcttc ggactttaag tcgcgttcca
     2221 gcttcaactg ttgggtcgga aacagcgggg tcaggttttc aaacaggatt ttatggcggc
     2281 atacttccgg gtggtcgccg ttgatggtat caagcctgac cagggcaaaa tagcgttcgt
     2341 tgtcttttgg gacgcgcacg cttccttcga tggtgtcgcc cgtatgcagg ttgaagcggc
     2401 ggatttgggt gggcgagaca tagatgtcgt cggggccggc aagataggac gtgtccgcgc
     2461 tgcggaggaa gccgaagccg tcgggcagga tttcaagcgt gccggagcag gtgaaaccct
     2521 cgcctttttt catcatctgg cggacgatgg caaatacgag gtcttgtttg cggaatcggt
     2581 tggcgttttc gatgccgtgt tcttccgcca attctaagag tttggaaatg tgcagggttt
     2641 gtaattcgga gacgtgcata ataatgatgt attttgaaga ggaaaaagac aggcagatgc
     2701 cgtctgaaag aagaagctga ccgttgccgg ttgctcgggg aagggggaat tgtaggcagt
     2761 cggcgcgtgg gtgtcaaata ttatcgcgga cggggcatcg gcaggaaatg ccgtctgagc
     2821 ggagctgctt ggaaaaaaat acccccgcgc ttttcaggct cgggggtatg ggcattgatt
     2881 atttgttcaa ttcattcgcc aaatacagcc aagtttcgat gacggtatcc gggttcaggg
     2941 aaacgctttc aatgccttcc tcaaccagcc atttggcgaa gtccggatgg tcggacgggc
     3001 cttgaccgca gatgccgaca tatttgttct gcttgcggca ggcggagatg gcaaggtgca
     3061 gcatcacttt gacggcaggg ttgcgttcgt caaacgattc ggataccaag ccgctgtcgc
     3121 ggtcgagacc gagggtcagt tgggtcatgt cgttcgagcc gatggagaag ccgtcgaagt
     3181 attgcaggaa ttgttccgcc aataccgcgt tgctcggcag ctcgcacatc ataatcaggc
     3241 gcaggccgtt tttgccgcgt tccaagccgt tttctttcag ggctttgaca acggcttcgg
     3301 cttcgcccaa ggtgcggacg aacggaatca tgatttcaac gttggtcaac cccatttcat
     3361 cgcggacgcg tttcaaggct ttgcattcca aggcgaaaca gtctttgaag ttgtcggcga
     3421 cataacgcgc cgcgccccgg aagcccaaca tcgggttttc ttcatgcggt tcgtatacgt
     3481 tgccgccgac caggttggcg tattcgttgg atttgaagtc ggacatacgg acgatggttt
     3541 tacgcggata aaccgatgcg gccaaagttg ccacgccttc tgcgatttta tcgacgtaga
     3601 agtcgacagg ggacgcatag ccggcgatgc ggcgggtaat ttccgctttc aattcgtcgt
     3661 cttgtttgtc aaattccaac aaggctttgg ggtggatacc gatttggcgg ttgatgataa
     3721 attccatacg cgccaagccg atgccttcgc tgggcaggtt ggcgaagctg aatgcgagtt
     3781 cgggattgcc gacgttcatc atgactttaa ccggtgcttt gggcatattg tctaaggcga
     3841 catcggtaat ctgtacgtcc aacagaccgg catagataaa gccggtatcg ccttcggcac
     3901 aggatacggt aacttcttga ccgtttttca gcaattcggt tgcattgccg cagccgacaa
     3961 cggcaggaat gcccaattca cgcgcgatga tggcggcgtg gcaggtacgg ccgccgcggt
     4021 tggtcacgat ggcagaagca cgtttcatca cgggttccca atccggatcg gtcatgtcgg
     4081 taacgagtac gtcgccggct tcgacggaat ccatctcgga agcatcttta atcaggcgca
     4141 ccttgccctg accgactttc tgaccgatgg cgcggccttc gcataatacg gttttgtcgc
     4201 cgttgatggc gaagcggcgc aggttgcggt tgccctcttc ttgggatttt acggtttcgg
     4261 gacgggcttg caggatgtag agtttgccgt ccaagccgtc gcgtccccat tcgatatcca
     4321 tcgggcggcc gtagtgtttt tcgatggtca gtgcgtaatg cgccaactca gtaatttctt
     4381 cgtcggtaat ggagaagcgg ttgcggtctt cctcggggac atcgacgttg gttacggatt
     4441 taccggcttc tgctttgtcg gtaaaaatca ttttgatgtg ttttgaaccc atggttttac
     4501 gcaggatggc gggcttgccc gctttgagcg tgggtttgaa cacataaaat tcgtccgggt
     4561 tgaccgcacc ttgtacgacg ttttcgccca gaccgtaaga ggaggtaaca aagacgactt
     4621 gatcgtagcc ggattcggtg tcgagggtga acatcacacc tgatgcgccg ctgtcggaac
     4681 gcaccatgcg ttgaacgccg gcggaaaggg cgacgatgtc gtgttcgaag cctttgtgga
     4741 cacggtaaga aatggcacgg tcgttataca gggaagcgaa tacatggtgc atcgcttctt
     4801 taacgttatc caagccgttg atgttcaaga aggtttcctg ttgtccagcg aatgatgcgt
     4861 ccggcaggtc ttcggcagtt gcggaagaac gtacggcaac ggaaatgtcc gcaccgccgg
     4921 catcggcaac cattttgttc catgccgctt cgatttcggc atcgagctgt tcggggaaag
     4981 gcgtatccaa aatccattgg cggatttctt tgccgacgcg tgccagttcg gcaacgtctt
     5041 cgacatccaa ttttgccagt gcggcggaaa tgcgttcgct cagaccgttg tgtgcgagga
     5101 atgcgcggta ggcatcggct gtggtggcaa agccgccggg gacgcgaacg cctttttcgg
     5161 tcagctgact gatcatttcg cccagcgagg cgtttttacc gcccacgcgt tcaacatctg
     5221 tcatacgcag gttttcaaac cagattacgt agttgtcggc catttgtgtg tccaatccaa
     5281 aatatgttaa aaaagaaaca aatccgcgtg cttattttaa gcgattcgtt cctctgctgt
     5341 catgtgtttt atccatttta aaatcatgat gccgtctgaa aaattgcggt ttcggcgtgt
     5401 gtagcggttt gaaacttgca gccggtatac ttcttttttt gggtattttc tttgtaaaac
     5461 aggtggtttg aataggttaa tgttttttct gtttgatttt tttgtttatt ttttaaaatt
     5521 ttctgccaaa aaatacttta tataaataat tttatttcaa aattatattg tgtctgtttg
     5581 ggtgtaatcc gaggtaggcg tgctgcgggt gctttccttg tgtctgccgc tgctgttatg
     5641 atgatatttt tattctgtat ttaaggatgg aagatgagca gtccgcgcca tgtgttttac
     5701 atttccgacc gtaccggtct gactgccgag aatatcggcg aggctttgct gaaccagttt
     5761 ggcaatctgt cgttcaaacg ccatacgcat ccgtttgtcg atacgccgga aaaggcgcgc
     5821 gcggtggtgg agaaggtcaa tcggagccgg caggaaaacg gtcagcgtcc gattgcgttt
     5881 gtcagtgtgg ttgatgacga aatccgtcgg attatcaaag gggcggatgc ttttcagatt
     5941 aatttctttg agactttttt gggactgttg gagaaagaac tcaataccga agccacggca
     6001 tccgagcagg ggtatcacag tatcggtaat acgaagcgtt acgatgcgcg tatggaggcg
     6061 gtaaatttct cattgaacca cgatgacggg gtcagcgata agaaccttca ggaagcggat
     6121 gtaatcttga tgggtgtatc gcgttcgggc aaaacgccga cctgccttta cctcgccctg
     6181 caatacggca tccgtgcggc aaactatccg ctgattcctg acgatttgga atcggccgat
     6241 ctgccgcgta tggtcaagcc ttatagggat aagctgttcg ggttgaccat ccagccggaa
     6301 cgtttgcagg ccatccgcca agagcgccgc ccgaattcaa cttatgccaa aatcgataca
     6361 tgccgcagcg aggtggcaga cgcgcagagt atgttcagac ggcatgggat tccgtttgcg
     6421 aatacgacgg ataaatcggt tgaggaattg gcggtacaca tccttcaggc gtgcaagctc
     6481 aaacgcaagt tttgacgggc tttgattcgg tttgaaggtg gaactgccgt ctgaaatcag
     6541 gtttcagacg gcagttttat agtggattaa caaaaatcag gacaaggcga cgaagccgca
     6601 gacagtacaa atagtacgga gccgattcac ttggtgcttc agcaccttag agaatcgttc
     6661 tctttgagct aaggcgaggc aacgacgtac tggtttagat ttaatccact atatgtttgt
     6721 ggggcggata tttttcaggg ctgtattttg tccagacatt cgagcagatc gagcggcgtg
     6781 cggatgtgga aatccgcctg ccatgagccg gtatcgtctt cgggagcgat gtagccccat
     6841 tcggcgagga cggttttcat gccggcgttg cggcctgctt ggatgtcgcg ttcggcatcg
     6901 ccgacgtaga gtgtgtgttg cgggtcggcg tggatttgtc cgcacgcata cagcatgggt
     6961 ttgacgctgg gcttgggttc gccgcaggtg tcgccgctga cgacgacggc gggtgggatg
     7021 atgaagccga gtttgggggc gagtttgtcg gtgaagcgca taggtttgtt ggtgatgatg
     7081 ccccatttga tgccgcgtct gtcgagttcg gcgatgagtt cgtttacgcc gccgaagagg
     7141 gtggtgtctt gggcgtagcg gctgtcgtat tcgtcaaggt attcggtgcg ccatcgggca
     7201 tagtcggggt gttcgggggt gatgcctgcg ccgagtttga gcagtcctgc cgcgccgtgg
     7261 ctggcttggg tgcggatttc gtccatgctt ttgggcggca gtccgtggcg ggcgagcagg
     7321 gtattgagtg cgccgccgag gtctagggcg gtgtcggcaa gcgtgccgtc gaggtcgaag
     7381 agtacggcgt gtatcatgtg tgttcctttt ttataaagtg cgggacgaag ggtttcagac
     7441 ggcatgttta ttttgtttca aaccctgctc gaaatcttcc aacatatcca attcaaagcg
     7501 gctgaagccc gctttttccc gcgcttcgat gttcacatag ccacggaaga taaacatatc
     7561 gtaacgggca atcagactgc ggaacagggc gacaggttcc aaaccgcgtt cgcggcagag
     7621 gtgttgatac caatggttgc cgatggcgac atggcccact tcgtcgcggt aaatgatgtc
     7681 caatacgccg caggtttccg aatcgccgcg ctgcgccacc ttcgcgcgta tccccggcgt
     7741 aacgtccagc ccgcgcgctt ccaacacgcg cggtaccaac gccatacgca acagcgggtc
     7801 gtaggcggtt ttgtacgcca tatcccacaa atggttgtgc gcctcgaaac tgccgtaatc
     7861 gaagccgaaa gcgcgcaatc tgtcgcgcat caggcggaaa tggtacacct cttccttcgc
     7921 cactttcacc cagtcgcgga caaactgaaa cggcagcgtg cggaaacggt atgccgcgtc
     7981 caaagctaga ttgacggcgt tgaattcgat atgcgcaatc gcgtgcagca tcgccgcata
     8041 accttcggtt gtgttcattt tgcgcggggt cagttgcgac ggcgcgacca aaacaggctt
     8101 gtccggccgt cccgctcggg ggaagtccgc cggcggcgcg tttgcttccg ccccgtccgc
     8161 attttgaacg gcggcaaacg cctcatccgt cagccgtcct ttttcatctg ggtcgcccga
     8221 aagcagggcg cgttccagca aagcataaat atcgagtttc atctcaagtc cgccgtgttc
     8281 ggaaaacaaa tattatagcg ttttaaaaaa acaagatgag gcatataatc tccgcgattc
     8341 ggcattccgc gcccaaaccg tca
//
LOCUS       DAXIDM010000083         8294 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000083 DAXIDM010000000
VERSION     DAXIDM010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8294
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.083"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(340..1086)
                     /locus_tag="ACFOAE_001561"
     CDS             complement(340..1086)
                     /locus_tag="ACFOAE_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFC6885020.1"
                     /translation="MDFRFDIIYEYRWMFLYGALTTLGLTVVATAGGSVLGLLLALAR
                     LIHLEKAGAPMRVLAWALRKVSLLYVTLFRGTPLFVQIVIWAYVWFPFFVHPSDGILV
                     SGEAAIALRRGYGPLIAGSLALIANSGAYICEIFRAGIQSIDKGQMEAARSLGLTYPQ
                     AMRYVILPQALRRMLPPLASEFITLLKDSSLLSVIAVAELAYVQNTITGRYSVYEEPL
                     YTVALIYLLMTTFLGWIFLRLEKRYNPQHR"
     gene            complement(1070..1249)
                     /locus_tag="ACFOAE_001562"
     CDS             complement(1070..1249)
                     /locus_tag="ACFOAE_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003708735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885021.1"
                     /translation="MNGKCRLKTARPAFLRRRATAVCRDKKVQAAVFTVKWRIILQRR
                     QFRRFLIRTVYGFSF"
     gene            complement(1265..1936)
                     /locus_tag="ACFOAE_001563"
     CDS             complement(1265..1936)
                     /locus_tag="ACFOAE_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HFC6885022.1"
                     /translation="MQIKKIMKWLPVALSLLGALGYTGYGSEAVRTAVAVLDVLGAAG
                     DAGSDAPARRRASAKSGHRYTGTVSKVYDGDTLHVIDGDGAKHKIRMAYIDAPEMKQA
                     YGTRSRDNLRAAAEGRKVSVRVFDTDRYQREVAQVSVGKTDLNLMQVQDGAAWHYKSY
                     AKEQQDKADFADYADAQIQAERERKGLWKAKNPQAPWAYRRAGRSGGGNKDWMDAVGE
                     WLGIW"
     gene            complement(2005..2676)
                     /gene="rpiA"
                     /locus_tag="ACFOAE_001564"
     CDS             complement(2005..2676)
                     /gene="rpiA"
                     /locus_tag="ACFOAE_001564"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFC6885023.1"
                     /translation="MTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSG
                     KKIKGAVSTSKKSSELLAQYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHL
                     NEKIVASASEKFICIADESKYVSRLGKFPLPVEVVESARSLVSRKLLAMGGQPELRIG
                     YTTFYGNQIVDVHGLNIDQPLTMEDEINKITGVLENGIFARDAADVLILGTEEGAKVI
                     YPCQG"
     gene            complement(2753..3235)
                     /gene="ispF"
                     /locus_tag="ACFOAE_001565"
     CDS             complement(2753..3235)
                     /gene="ispF"
                     /locus_tag="ACFOAE_001565"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HFC6885024.1"
                     /translation="MTNIRIGQGYDVHQLTEGRKLILGGVEIPFEKGLLGHSDADALL
                     HAVTDALLGAAGLGDIGSHFPDTAAEFKDADSRVLLRAAYQSVQAQGWQAVNVDTTVI
                     AQKPKLAPHIPQMRANIAADLGIDISCVNIKGKTNEKLGYLGRMEGIEAQAAVLLVRI
                     "
     gene            complement(3267..3956)
                     /gene="ispD"
                     /locus_tag="ACFOAE_001566"
     CDS             complement(3267..3956)
                     /gene="ispD"
                     /locus_tag="ACFOAE_001566"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HFC6885025.1"
                     /translation="MKRKNIALIPAAGIGARFGADKPKQYVEIGSKTVLEHTLGIFER
                     HEAVDLTVVVVSPEDTFADKVQTAFPQVRVWKNGGQTRAETVRNGVAKLLETGLAAET
                     DNILVHDAARCCLPSEALTRLIEQAGNAAEGGILAIPVADTLKCADGGNISATVERTS
                     LWQAQTPQLFRAGLLHRALAAENLDGITDEASAVEKLGVRPLLIQGDVRNLKLTQPQD
                     AYIVRLLLDAV"
     gene            complement(3953..4687)
                     /gene="dnaQ"
                     /locus_tag="ACFOAE_001567"
     CDS             complement(3953..4687)
                     /gene="dnaQ"
                     /locus_tag="ACFOAE_001567"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HFC6885026.1"
                     /translation="MIQRQIILDTETTGLYADGGDRLVEFAGLEMVNRQMTDKNLHLY
                     VHPERDMPEEAARVHGLTIEVLEGKNAPPFAEVGRQIADFLRGAELIIHNAKFDVGFL
                     NMEFRRMGLPTVEELGCTVTDTLAMAREMFPGQKASLDALCNRFSVDRSKRVLHGALI
                     DCELLGEVYLAMTRRQFDLMGAAAEEKMETKPVAHTETKRSGKLKVIRADENELAEHG
                     RYLDGLGEACIWRKTQMPSENGGTEA"
     gene            complement(4845..6155)
                     /locus_tag="ACFOAE_001568"
     CDS             complement(4845..6155)
                     /locus_tag="ACFOAE_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC6885027.1"
                     /translation="MYAKKGGLGLVKSRRFAPLFATQFLGAFNDNVFKTALFVMIGFY
                     GLGQNGFLPAGQMLNLGALLFILPYFLFSSLSGQLGNKFDKAVLARWVKVLEMIIMAV
                     AAYGFYIRSAPLLLACLFCMGAQSTLFGPLKYAILPDYLDDKELMMGNSLIESGTFVA
                     ILFGQILGTAVAGVPPYIVGILVLLVAVGGTVGSLFMPSVPAKAADTQIEWNIVRGTK
                     SLLRETVRHKPVFTAIIGISWFWFVGAVYTTQLPTFTQIHLGGNDNVFNLMLALFSIG
                     IAAGSVLCAKFSRERLMLAWVTVGALGLTVCGLVLVWLTHGHRFEGLNGIFWFLSQGW
                     AYPVMAVMTLIGFFGGFFSVPLYTWLQTASSETFRARAVAANNIVNGIFMVSAAVLSA
                     VLLFLFDSISLLYLIVALGNIPLSVFLIKRERRFLGAAAIRKKP"
     gene            complement(6145..6330)
                     /gene="ccoS"
                     /locus_tag="ACFOAE_001569"
     CDS             complement(6145..6330)
                     /gene="ccoS"
                     /locus_tag="ACFOAE_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008535 - respiratory chain complex IV
                     assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome oxidase assembly protein
                     CcoS"
                     /protein_id="HFC6885028.1"
                     /translation="MESMFILVPISIILAFVIGWFFWWSGKNGQFDDLEGPAHRILMD
                     DDSTSKLIEKERENDVR"
     gene            complement(6330..6629)
                     /locus_tag="ACFOAE_001570"
     CDS             complement(6330..6629)
                     /locus_tag="ACFOAE_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885029.1"
                     /translation="MHYFSIHDQSGRHIGFFILLADDESEARPQSGRFAVKLEGGMEN
                     HVLSPFGQTEIPQYWRVVKDRIELFFDEAPVGTLRNEYLTVSGQTFVLNDLTGNM"
     gene            6980..8176
                     /locus_tag="ACFOAE_001571"
     CDS             6980..8176
                     /locus_tag="ACFOAE_001571"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HFC6885030.1"
                     /translation="MSQKLILVLNCGSSSLKGAVLDNGSGEVLLSCLAEKLNLPDAYI
                     TFKVNGEKHKVDLSAHPDHTGAVEALMEELKAHGLDSRIGAIGHRVVSGGELYSESIL
                     VDDEVIAGIEKCIPLAPLHNPAHLLGLRAAQSIFKGLPNVVVFDTSFHQTMPEVAYKY
                     AVPQELYEKYGLRRYGAHGTSYRFVADETARFLGKDKKDLRMVIAHLGNGASITAVAN
                     GESRDTSMGLTPLEGLVMGTRSGDIDPSVFGFLAENANMTIAQITEMLNKKSGLLGIS
                     GLSNDCRTIEEEAAKGHKGAKLALDMFIYRLAKYIGSMAVAAGGLDALVFTGGIGENS
                     DIIRERVIGYLGFLGLNIDQEANLKARFGNAAVITTADSKAVAVVIPTNEELMIAHDT
                     ARLSGL"
BASE COUNT         1950 a         2470 c         2034 g         1840 t
ORIGIN      
        1 gatgtaggtt cgtaggaatg acgtggtgca ggtttccgta tggatgggat tccctcttgc
       61 gtgaggctga cagatgccgt ctgaaagact ttcagacggc atagcttttt ctctttgaat
      121 ttatagtgga ttaacaaaaa tcaggacaag gcggcgagcc gcagacagta cagatagtac
      181 ggaaccgatt cactcggtgc ttcagcacct tagagaatcg ttctctttga gctaaggcga
      241 ggcaacgccg tactggtttt tgttaatcca cgataaattt gccacaaaaa agctgcctca
      301 aatgaatacc cgggcagctt tttgttgata tgactccaat cagcggtgtt gcggattgta
      361 acgtttttcc aaacgcagga atatccagcc taagaaagtc gtcatcaaca gataaatcag
      421 ggcgacggtg taaagcggtt cttcataaac cgaataccgg cccgtaatcg tattctgaac
      481 atacgccaac tccgccacag caatgaccga cagcagcgag ctgtctttca agagcgtgat
      541 gaactcgctc gccaaaggcg gcagcatgcg gcgcaatgcc tgcggcagaa tcacatagcg
      601 catcgcctgc ggataggtca gccccaaaga acgcgccgcc tccatctgtc ctttgtctat
      661 agactggatg cccgcgcgga aaatctcaca gatatacgcc cccgagttgg cgatcagtgc
      721 caaagaaccg gcaatcagcg gcccgtatcc gcgacgcagc gcgattgccg cctcgccgct
      781 gaccaaaatg ccgtctgaag gatggacgaa aaacggaaac cacacatacg cccaaatcac
      841 aatctgcaca aacagcggcg taccccggaa cagcgtaaca tacagcagcg aaactttacg
      901 caacgcccac gccagcacgc gcatcggcgc accggctttt tccaagtgaa tcaggcgcgc
      961 caacgccaac aacagaccca ataccgaacc gcccgccgtc gccacgaccg tcagccccaa
     1021 ggtcgtcagt gcgccgtaaa ggaacatcca gcggtattcg taaataatgt caaaacgaaa
     1081 atccatatac cgtccgtatc aaaaaccggc ggaactgccg ccgttgcaaa ataatccgcc
     1141 attttaccgt aaaaaccgcc gcctgaactt ttttatcgcg gcagacggcg gttgcgcgtc
     1201 tccgcaaaaa tgcagggcgc gcggttttca gacggcattt gccgttcaaa gccgtgcgct
     1261 gtctttacca aatgcccaac cattcgccca cggcatccat ccaatcctta ttgcccccgc
     1321 cgctcctgcc tgctcggcgg tacgcccacg gcgcttgcgg atttttagct ttccacaatc
     1381 ctttgcgttc cctttccgcc tgaatttgag cgtcggcata gtcggcaaaa tccgccttat
     1441 cctgctgttc tttagcataa cttttataat gccacgccgc cccgtcctgc acttgcatca
     1501 ggttcaaatc ggttttgccg acagaaacct gcgccacttc gcgctggtag cggtcggtgt
     1561 cgaacacgcg cacgctgact ttcctgcctt ccgccgccgc acgcaggttg tcgcgcgaac
     1621 gcgtgccgta agcctgtttc atctccggcg cgtcgatata cgccatccgg attttgtgtt
     1681 tcgcgccgtc gccgtcgata acgtgaaggg tgtcgccgtc atagactttg gacaccgtgc
     1741 ctgtgtagcg gtggccggat ttcgccgatg ctcggcggcg ggcgggcgcg tcggaacccg
     1801 cgtcccctgc cgcgccgagt acgtcgagta cggcaaccgc cgtccgcacc gcctcgctgc
     1861 cgtaccccgt ataacccaac gcacccaaaa gcgacaaggc gacgggaagc catttcatga
     1921 tttttttaat ctgcatattt ttcaaatgcc gatgccgtct gaacatatcg gaatcggatt
     1981 tcagacggca tcttaacgtc aggattaccc ttggcaggga tagatgactt tcgcaccctc
     2041 ttccgtcccc aaaatcaaca catcggcggc atcgcgggcg aatatgccgt tttcgagcac
     2101 gccggtgatt ttgttgattt cgtcttccat cgtcagcggc tgatcgatat tcaagccgtg
     2161 gacatcgacg atttggttgc cgtaaaacgt ggtgtagccg atacgcagtt cgggctgtcc
     2221 gcccatagcg agcagtttgc gcgaaacaag ggaacgcgcg ctttcgacga cttccacggg
     2281 cagagggaat ttgcccaaac gtgaaacata tttgctttca tccgcaatgc agatgaattt
     2341 ttctgatgcg ctggcgacga ttttttcgtt gaggtgcgcg ccgccgccgc ccttaatcat
     2401 ttgcagggcg tggttcactt catccgcacc gtcgatatag accgccaaac ccgatacttc
     2461 gttcagggaa acgacgggaa tgtcgtactg ggcaagcagt tcgctggatt ttttggaggt
     2521 tgaaaccgcg cctttgattt ttttgccgct tttgcccaag gcttcgatga aaaagttgat
     2581 ggtcgagccg gtaccgatgc cgatgtattc gttttcgggt acgaattcga ctgctttttc
     2641 ggcggcgatg cgcttgagtt cgtcttgtgt cgtcatattt ttgtcctttg ggaaaccgta
     2701 tcaacaaaca gccgccatct taacattttt ttgcacgtcc tgcccgccgc gttcaaatcc
     2761 ttaccagcaa taccgccgcc tgcgcctcta tgccttccat gcgcccgaga taaccgagtt
     2821 tttcgttggt tttgcctttg atgttgacgc acgaaatgtc tatgcccaaa tcggcggcga
     2881 tgttggcacg catttgcgga atatgcggcg cgagtttggg tttctgtgca atcacggtcg
     2941 tatcgacatt gaccgcctgc caaccctgcg cctgaacact ttgatacgcc gcacgcaaaa
     3001 ggacgcggct gtccgcatct ttgaactctg cggcggtgtc ggggaaatgg ctgccgatat
     3061 cgcccaaacc tgccgcaccg agcagcgcgt cggtaacggc gtgcagcagc gcatcggcat
     3121 cggagtgtcc gagcagccct ttttcaaatg ggatttcaac tccgccaagt atcagctttc
     3181 tgccttcggt cagttggtgg acatcgtagc cctgtccgat acggatgttc gtcatcgttt
     3241 gtgttcctga tgttttgaat tgaagttcag acggcatcga gcagcagcct gacgatgtat
     3301 gcgtcctgcg gctgcgtcag tttcaaattg cgcacgtcgc cctgtatcag tagcggacgc
     3361 acacccaatt tttccacggc ggacgcttca tcggtaatgc cgtccaagtt ttccgcagcc
     3421 aatgcgcggt gcagcagccc ggcgcggaaa agctgcggcg tttgtgcctg ccaaaggctc
     3481 gtccgctcga cggttgcact aatgttccca ccgtccgcgc acttgagcgt atcggcaacg
     3541 ggaattgcca aaatcccacc ttcggcagcg ttgcccgcct gttctatcaa ccgcgtcaaa
     3601 gcttcagacg gcaggcagca acgcgcggca tcgtgtacca gaatattgtc ggtttccgcc
     3661 gccaaaccgg tttccaacag ttttgccaca ccgttgcgga cggtttcggc gcgggtctgt
     3721 ccgccgtttt tccacacccg aacctgtgga aatgccgtct gaaccttatc ggcaaacgtg
     3781 tcttcgggcg agacgacaac gacggtcaaa tcgacggcct catgccgttc aaaaatccca
     3841 agcgtatgtt ctaaaacggt tttgcttccg atttcgacat actgcttggg tttgtccgca
     3901 ccgaaacgcg ccccgatgcc ggcggcggga atcagggcga tatttttgcg tttcatgcct
     3961 ccgtcccgcc gttttcagac ggcatctgcg tcttgcgcca gatacaggct tcgcccaagc
     4021 cgtccaaata tcgcccgtgc tccgccaact cgttttcgtc cgccctgatg actttcagtt
     4081 tgccgctgcg tttggtttcg gtatgcgcca cgggtttggt ttccattttt tcctctgcgg
     4141 ccgcacccat caggtcgaat tgccgccgcg tcatcgctaa ataaacttcg cccaaaagct
     4201 cgcagtcgat cagcgcgccg tgcaggacgc gcttgctgcg gtcgacggaa aaacggttgc
     4261 acaaggcatc caggctggct ttctgcccgg ggaacatttc gcgcgccatc gccagggtat
     4321 cggtaacggt acagccgagt tcctcaacgg tcggcaaccc catccggcgg aactccatat
     4381 tgaggaagcc cacgtcgaat ttggcattgt ggataatcag ttccgcaccg cgcaggaaat
     4441 cggcaatctg cctgccgacc tctgcaaacg gcggcgcgtt tttcccttcc aaaacctcta
     4501 tcgtcagacc gtgcaccctc gccgcctctt cgggcatatc gcgctcgggg tggacataga
     4561 ggtgcaggtt tttgtcggtc atttggcggt tgaccatttc cagaccggca aactcgacca
     4621 agcggtcgcc gccgtcggca tacaggccgg tggtttcggt atcgaggatg atttggcgtt
     4681 gaatcatgtc tgcttctttc ttcaaatttt ccatctgctg actatttttt aggcagcgta
     4741 tttttctgtt ttcatttcaa tgcacaaacc cacttattca cagtgtgttc acaacattgg
     4801 gcaggcggat tgtgtatttt ggggacaatt ttttcagacg gcattcaagg ttttttcctg
     4861 attgccgccg cgcctaaaaa ccgcctttcg cgcttaatca aaaataccga caacggaata
     4921 ttgcccaaag cgacaatcag atacaacaag gaaatgctgt caaacaaaaa cagcaacacc
     4981 gcgctcaaaa cggcggcgga aaccataaaa ataccgttaa cgatattgtt ggcggcaacg
     5041 gcgcgggcgc ggaaagtctc gctactggcg gtttgcagcc aagtatagag cggaacggag
     5101 aaaaatccgc cgaaaaagcc gatcagcgtc atcaccgcca tcacgggata tgcccatcct
     5161 tgcgataaaa accaaaaaat gccgttcagc ccttcaaaac ggtgtccgtg cgtcagccac
     5221 accaaaacca ggccgcaaac cgtcaaaccc aacgcaccaa ccgttaccca agccaacatc
     5281 agccgttccc tgctgaactt ggcacacagt accgaaccgg cggcaatacc gatggaaaac
     5341 agagcaagca tcaggttgaa aacattgtcg ttgccgccca gatggatttg ggtaaaggtc
     5401 ggcagttgcg tggtataaac cgcgccgaca aaccaaaacc acgaaatacc gataatggcg
     5461 gtaaaaacgg gcttgtgccg caccgtttca cgcagcaggg attttgtgcc acggacaata
     5521 ttccactcaa tttgtgtatc ggcagccttg gcgggtacgg acggcataaa caggctgccg
     5581 accgtgcctc cgacggcgac cagcaaaacc agtatcccga caatataagg cggtacacct
     5641 gccaccgccg ttcccaaaat ctgaccgaac aggatggcga caaacgtacc cgattcaatc
     5701 aggctgttgc ccatcatcaa ctctttgtcg tcgagataat cgggcaggat ggcgtatttc
     5761 agcggcccga acagcgtcga ttgcgcgccc atgcaaaaca gacacgccaa aagcagcggg
     5821 gcagaccgga tataaaaccc gtatgccgcc accgccataa tgatcatttc cagcaccttg
     5881 acccaacgcg ccaaaacggc cttgtcgaat ttgttaccca actgccccga cagcgaggaa
     5941 aacaggaaat acggcaaaat aaacagcaac gcgcccaagt tcaacatctg tccggcaggc
     6001 aggaagccgt tttgccccaa accgtaaaac ccaatcatca caaacagcgc ggttttgaac
     6061 acattgtcgt tgaacgcgcc gagaaactgc gtagcgaaaa gaggtgcgaa acggcggctt
     6121 ttaaccagtc ccaaaccgcc ttttttagcg tacatcgttt tccctctctt tttcaatcag
     6181 tttacttgtc gaatcatcat ccatcaggat gcggtgcgcc ggcccttcca agtcgtcaaa
     6241 ctgcccgttt ttgcccgacc accaaaaaaa ccagccgatg acaaacgcca aaataatgct
     6301 gatgggcacc aatataaaca tgctttccat cacatattcc ctgtcaaatc gttcaaaaca
     6361 aaagtctgcc ccgacacggt cagatattcg ttacgcaaag ttccgacggg agcttcgtca
     6421 aaaaacagct cgatacggtc tttgaccacg cgccaatatt gggggatttc cgtctgaccg
     6481 aacggcgaca ggacatgatt ttccattccg ccttcaagtt tgacggcaaa acgcccgctt
     6541 tgcggccgtg cttccgattc gtcgtcggca agcaggatga aaaagcctat atgccgtccc
     6601 gattggtcat gaatactgaa ataatgcata aatttcccac ccgccttttt tcagacgaca
     6661 ccaactaaaa acagggcgaa tgtaccagtt tggacgggaa gaatgcaaag aaattctccc
     6721 tcccccagcc gaaaacaccg gcaaaccgca tatccccctt ttttccgtca aaatgcccga
     6781 cttccgccat tttcacgcaa acgcccgatt aagccaagca attgcaaaga ttttttgcta
     6841 gaatagcctg cttcttttat caaccttttc agacggcccc actactttcc cgcccaggaa
     6901 ggcaaaacgg attcggcacg aatccggtta gtatccgtgt ccgattccaa tgccgtctga
     6961 aactttccgg agtaagaaaa tgtcccaaaa attgatcttg gttttgaact gcggcagctc
     7021 gtccctcaaa ggcgcggtcc tggataacgg cagcggcgaa gtcctgctca gctgccttgc
     7081 cgaaaaactc aacctgcccg atgcctacat cacattcaaa gtaaacggcg aaaaacacaa
     7141 agtcgatctg tccgcacatc ccgaccacac cggcgcggtc gaagccctga tggaagaact
     7201 caaagcccac ggcctcgaca gccgcatcgg cgccatcggc caccgcgtcg tcagcggcgg
     7261 cgaactgtac agcgaatcca tcctcgttga cgacgaagtc attgccggca tcgaaaaatg
     7321 catcccgctc gcccccctgc acaaccccgc ccacctcttg ggcctgcgtg ccgcgcaaag
     7381 cattttcaaa ggcctgccca acgtcgtcgt attcgatacc tccttccacc aaaccatgcc
     7441 cgaagtcgcc tacaaatacg ccgttccgca ggagttgtat gaaaaatacg gcctgcgccg
     7501 ttacggcgcg cacggtacca gctaccgctt cgtcgccgac gaaaccgcgc gcttcctcgg
     7561 caaagacaaa aaagacctgc gtatggtcat tgcccacttg ggcaacggcg cgtccatcac
     7621 cgccgtcgcc aacggcgaat cgcgcgacac cagtatgggc ctgaccccac tggaagggct
     7681 ggtaatgggt acgcgcagcg gcgacatcga tccttccgta ttcggcttcc tcgccgaaaa
     7741 cgccaatatg accatcgccc aaatcactga aatgctgaac aaaaaatccg gtctgctcgg
     7801 catttccggt ctgtccaacg actgccgcac cattgaagaa gaagccgcca aggggcataa
     7861 aggcgcgaaa ttggccttgg atatgtttat ctaccgcctt gccaaataca tcggcagtat
     7921 ggcggttgcc gcaggcggct tggacgcact ggtctttacc ggcggcatcg gcgaaaactc
     7981 cgacatcatc cgcgaacgcg tgatcggcta cttgggcttc ctcggtctga acatcgacca
     8041 agaagccaac ctaaaagccc gcttcggcaa cgccgccgtg attaccactg ccgacagcaa
     8101 agccgttgcc gtggtcattc cgactaacga agagctgatg attgcccacg acactgcccg
     8161 tttgagcggt ctgtaaggtt ttatccgcac acgaactgcc tccggaaatg gaggcagttt
     8221 ttttatccgg ctttccatgc ttaaacagca ctgcctcttt tcagacattg acggttgcag
     8281 ccgcttacct gaac
//
LOCUS       DAXIDM010000084         8242 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000084 DAXIDM010000000
VERSION     DAXIDM010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8242
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.084"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(252..980)
                     /gene="rmpM"
                     /locus_tag="ACFOAE_001572"
     CDS             complement(252..980)
                     /gene="rmpM"
                     /locus_tag="ACFOAE_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding outer membrane protein
                     RmpM"
                     /protein_id="HFC6885031.1"
                     /translation="MTKQLKLSALFVALLASGTAVAGEASVQGYTVSGQSNEIVRNNY
                     GECWKNAYFDKASQGRVECGDAVAAPEPEPEPEPAPAPVVVVEQAPQYVDETISLSAK
                     TLFGFDKDSLRAEAQDNLKVLAQRLSRTNIQSVRVEGHTDFMGSDKYNQALSERRAYV
                     VANNLVSNGVPVSRISAVGLGESQAQMTQVCEAEVAKLGAKVSKAKKREALIACIEPD
                     RRVDVKIRSIVTRQVVPAHNHHQH"
     gene            1344..2294
                     /locus_tag="ACFOAE_001573"
     CDS             1344..2294
                     /locus_tag="ACFOAE_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CysB family HTH-type transcriptional regulator"
                     /protein_id="HFC6885032.1"
                     /translation="MKLQQLKYALEVYQHNLNVSEAAEALFTSQPGISKQIKLLEEEI
                     GIQIFIRSGKRVVSVSQPGKVVLDIAERILRDVQNIKNIGSEFTGQDSGSLTVATTHT
                     QARYALPLIVADFVKRYPKVNLTIKQGSPAAIARMVTSGEADLAIVTERIDDHPELGK
                     LPCYDWTHAVIVPNDHPLLECRNPLRIEDLARFPLITYEFAFNAGSSIARAFSKARLE
                     QPDVALAAADTDVLKTYVRLGLGVGLMAKMAYNPDTDGDLQLVDAAHLFEPSPTWIAL
                     RSDTYLRGYAYDFIQAFAPHLTREKVDRILYTPISEDFSI"
     gene            complement(2407..3141)
                     /gene="fnr"
                     /locus_tag="ACFOAE_001574"
     CDS             complement(2407..3141)
                     /gene="fnr"
                     /locus_tag="ACFOAE_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HFC6885033.1"
                     /translation="MASHNTTHQMKTLCSSCSLRELCLPVGLLPNELSQLDAVIRQSR
                     RLKKGEYLFCVGEAFTSLFAIRSGFFKTTVASQDGRDQVTGFFMSGELIGMDGICSHV
                     HSCDAVALEDSEVCELPFTHIEELGQNIPSLRTHFFRMMSREIVRDQGVMLLLGNMRA
                     EERIAAFLLNLSQRLYSRGFAANDFILRMSREEIGSYLGLKLETVSRTLSKFHQEGLI
                     SVEHKHIKILNLQVLKKMVSGCSHAI"
     gene            3344..4765
                     /gene="hemN"
                     /locus_tag="ACFOAE_001575"
     CDS             3344..4765
                     /gene="hemN"
                     /locus_tag="ACFOAE_001575"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003684340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004109 - coproporphyrinogen oxidase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HFC6885034.1"
                     /translation="MKIIQIQNKHNVNDDRPEFDRALIASLPASGPRYTSYPTADRFH
                     DGFREGEYIKALHLRGMGALNKPLSLYIHIPFCNTICYYCGCNKIITKDKSRADAYIE
                     YLEKEMELLAPHLNGRHQLAQLHFGGGTPTFLSDEQIERVFRMIRKHFELIPTGEYSI
                     EIDPRKVSRDTVLMLGRLGFNRMSIGIQDFDPKVQAAVNRIQSYEETKEVIDAAREAG
                     FKSVSVDLIYGLPHQTSESIKTTIDTVLSLDPDRLALYHYAHLPHVFKPQRRIDTAAV
                     PDSEEKLDMLQYCVQTLTERGYVFIGMDHFAKPDDELSIALKEGFLQRNFQGYSTYAD
                     CDLVAIGVSSIGKIGSTYSQNERDIDAYYAAIDEGRLPIMRGYQLNQDDILRRNIIQD
                     LMCRFALDYRIYESMFGIPFDRYFKDELADLEKLAGLGLVRLNSHGLTVTPKGRFLIR
                     NIAMVFDYHLRHKETKAKYSQTV"
     gene            complement(5118..6692)
                     /locus_tag="ACFOAE_001576"
     CDS             complement(5118..6692)
                     /locus_tag="ACFOAE_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003748724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HFC6885035.1"
                     /translation="MAQIQMSANVKTINAVFAAMLVGTVGYFIYWGLGYTHYNYAALF
                     IIATMFGVFMAFNIGGNDVANSFGTSVGAGTLTIPQALLIAAVFEVSGAVIAGGEVTN
                     TIRKGIVDLKGVDFEPIQFVFIMMSALLAAALWLLFASKKGLPVSTTHSIIGGIVGSA
                     VCMAVMNDAASGDLIRWGKLGGIGVSWVLSPVLGGAVSYFLFSRVKKNVLDYNAWAEG
                     TLKGIKQEKKAYKERHRLFFEGLSEAEKVEYATKMAHDAQIYDEPEFDPQELQSEYYR
                     GLYAFDNRKNNVDSYKALHSWIPFIASFGAMMISAMLIFKGLKNLHLGMSNVNSFLTI
                     FMIGAAVWMGTFVFAKSLKRKDLGKSTFQMFSWMQVFTACGFAFSHGANDIANAIGPF
                     AAIMDVLRTNSVAAQNVVPPIAMLTFGIALIVGLWFVGKEVIKTVGTSLAEMHPASGF
                     TAELSAASVVMGASLMGLPVSSTHILVGAVLGIGLVNRNANWKLMKPIGLAWVITLPA
                     AAVLSVVCYLVLQAVF"
     gene            7017..8117
                     /locus_tag="ACFOAE_001577"
     CDS             7017..8117
                     /locus_tag="ACFOAE_001577"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0006040 - amino sugar metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HFC6885036.1"
                     /translation="METQLYIGIMSGTSMDGADAVLVRMDGGKWLGAEGHAFTPYPDR
                     LRRQLLDLQDTGADELHRSRILSQELSRLYAQTAAELLCSQNLAPSDITALGCHGQTV
                     RHAPEHGYSIQLADLPLLAELTQIFTVGDFRSRDLAAGGQGAPLVPAFHKALFRDDKE
                     TRVVLNIGGIANISVLPSDAPAFGFDTGPGNMLMDAWTQAHWQLPYDKNGAKAAQGNI
                     LPQLLDRLLAHPYFAQPHPKSTGRELFALNWLETYLDGGENRYDVLRTLSRFTAQTVC
                     DAVSHAAADARQMYICGGGIRNPVLMADLAEYFGTRVSLRSTAELKLDPQWVEAAAFA
                     WLAACWINRIPGSSHKATGASKPCILGAGYYY"
BASE COUNT         2080 a         2298 c         2020 g         1844 t
ORIGIN      
        1 gcggcaatgg gacacaaacc tgaatctgaa tctgaatctg aatctgaatc tgaatctgaa
       61 tccgaatccg aatccgaacc tgcaccccga ttctgacgat agccgtttca gaaaaccacc
      121 caaaaaaaca aaccccgcaa aagcgggggt ttgtttcaca tcatcgatgc cgaccgacgt
      181 ttcacgaata ttgcaacagt acctggtaca aaatccacta acctcatgca tcggcaagat
      241 attgcctagc cttagtgttg gtgatgattg tgtgccggca caacctgacg ggttacgatg
      301 ctgcggattt tcacatccac acggcggtca ggttcgatac atgcaatcag agcctcacgt
      361 tttttggctt tagagacttt cgcacccagt ttggcaactt cggcttcaca aacttgagtc
      421 atttgcgctt gagattcgcc caagccaaca gcagaaattc tagaaacagg tacgccgttg
      481 ctgaccaggt tgtttgccac tacgtatgcg cggcgttcgg acagggcctg attgtatttg
      541 tcagaaccca taaagtcggt atggccttcg acgcggacag attggatatt ggttcgactc
      601 aggcgttgcg ccaatacttt caggttgtct tgagcttcgg cgcgcaatga atccttatcg
      661 aaaccgaaca gggttttggc agacagggaa atggtttcat caacatattg cggagcctgc
      721 tccacaacga cgacaggcgc gggtgcgggt tcgggttctg gctcgggttc gggggcagca
      781 accgcatcgc cgcattctac gcgaccttgg cttgctttat caaagtaggc gtttttccag
      841 cattcgccat agttgttgcg tacgatttcg ttcgactggc cgcttacggt gtaaccctga
      901 acggacgcct cgcccgcaac agcagtgccg gaagcgagca atgcaacgaa taatgcgctt
      961 aatttcagct gtttggtcat tttattccct cattaaattt gtacagcaga tacagaagca
     1021 actgctgaat tgccaacata caggccgctg tagaaacatg gcggcaaatc ggatatttca
     1081 gtctccacta taaagaagca gggggcggac tgtcaatact caacgcctga aaacaaccgt
     1141 aaaacagcct gtttcctgat agtctatcat gccgaaaaat caattccgtg tcattacttt
     1201 agggggattt tttccatatc gcacgattgc cgttgcacaa aaacaacaaa cacaacggca
     1261 aagccccata ccgtaccggc aagaaaatat gataaattat aaacaatgtt cagccacccg
     1321 acacagaccc acaccgaccc gccatgaaat tacaacaatt gaaatacgcc ttagaagttt
     1381 accagcacaa cctgaacgtt tccgaagcgg ccgaagcctt gtttacttcg caacccggca
     1441 tctccaaaca aatcaaattg ctggaagaag aaatcggcat tcagattttt atccgcagcg
     1501 gcaagcgcgt ggtttcggtc tcgcagccgg gcaaggtggt tttggatatt gcagaacgta
     1561 ttttacgcga tgtacagaac attaaaaata tcggcagcga gtttaccgga caggacagcg
     1621 gttcgctgac ggttgccacg acgcatactc aggcacgcta tgccctaccc ttgattgttg
     1681 ccgattttgt gaaacgctat ccgaaagtca acctgaccat caaacagggg agccctgccg
     1741 ccatcgcacg tatggttacc tcaggcgagg cggacttggc gattgttacg gaacggatag
     1801 acgaccatcc cgaactggga aaacttccct gctatgactg gactcatgcg gttatcgtac
     1861 cgaacgacca ccccttgctc gaatgcagaa accccctccg cattgaagat ttggcgaggt
     1921 ttccgctgat tacttatgaa tttgcattca atgcgggcag cagcatcgcg cgggcatttt
     1981 ccaaagcccg tttggaacag ccggatgtcg cattggcggc ggcggatacg gacgtattga
     2041 agacttatgt gcgcttgggt ttgggcgtgg gactgatggc gaaaatggcg tacaacccgg
     2101 atacggacgg cgatttgcag cttgtggatg cggcacacct gttcgagccg tcgccgacgt
     2161 ggattgcttt gcgcagcgat acttatttgc gcggatatgc ctacgacttt atccaagcgt
     2221 ttgcgccgca cctgacacgc gagaaagtgg ataggattct gtacacgccc atcagcgagg
     2281 atttttcgat ttaggcggct gccggttttc agacggcact ttgcggcaga tacaacaaac
     2341 aggacagatg ttttcgtctg ccctgtgttt attgagaatg ccgtctgaaa tgttcgtacg
     2401 ggttaatcaa atggcgtgcg agcagccgga caccattttt ttcaacacct gcagattgag
     2461 gatcttgatg tgtttgtgtt cgacggaaat caatccttcc tgatggaact tggataatgt
     2521 gcggctgacg gtttcaagtt tcagcccgag ataactgccg atttcttcgc gggacattct
     2581 taagatgaag tcgttggcag caaaacctcg ggaataaagg cgttgggaaa ggttcagcag
     2641 gaaggcggca atccgctctt cggcgcgcat attgcccaac agcagcataa caccttggtc
     2701 gcgcacgatt tcacggctca tcatgcggaa gaagtgcgta cgcaggctgg ggatgttttg
     2761 ccccagttct tcgatgtggg taaacggcag ttcgcacact tcgctgtctt ccaaggcgac
     2821 cgcgtcgcaa ctgtgcacat gggaacagat gccgtccatg ccgatgagtt cgcccgacat
     2881 aaagaaaccc gttacctgat cgcggccgtc ctgactggcg acggttgttt tgaagaagcc
     2941 cgaacggatg gcaaagagcg aggtaaaggc ttcgccgaca cagaacaggt attcgccctt
     3001 tttcaggcgg cggctttgac ggatgacggc atcgagttgg ctgagctcgt tgggcagcag
     3061 cccgacaggc aggcagagtt cccgcaaaga acaggaagaa cacagcgttt tcatctgatg
     3121 tgtagtatta tgcgaagcca taccgtacct ttttgtgcgc tttgccccat catgattata
     3181 gtggattaaa tttaaaccag tacggcgttg cctcgccttg tccttattta aatttaatcc
     3241 actatatgtg cttattgaca catatcaaga caggtttatc atactgtggc attctaccaa
     3301 actatccaaa atttgactaa catcataaaa tcgcacacac accatgaaaa tcattcagat
     3361 acagaacaag cacaatgtaa acgatgaccg ccccgagttt gaccgcgcgc tgattgccag
     3421 cctgcccgcc agcggtccgc gctacacttc ctaccctacc gccgaccgtt tccatgacgg
     3481 tttccgcgaa ggcgaatata tcaaagcttt acatttgcgc ggtatgggcg cgttaaacaa
     3541 accgctttcc ctttacattc acattccgtt ctgcaacacc atctgctact actgcggctg
     3601 caacaaaatc atcaccaaag acaaaagccg cgccgatgcc tacatcgaat atcttgaaaa
     3661 agaaatggaa ctgctcgctc cacatctgaa cggacggcac cagcttgccc aactgcactt
     3721 cggcggcggc acgccgacct ttttgagcga cgaacagatc gaacgtgtct tccgcatgat
     3781 acgcaaacat ttcgagttaa tccccaccgg cgaatactcc atcgaaatcg acccgcgcaa
     3841 agtcagccgc gacaccgtcc tcatgctcgg cagactcggc ttcaaccgca tgagcatcgg
     3901 cattcaggat ttcgacccca aagtgcaggc ggcggtcaac cgcatccaaa gttacgaaga
     3961 aaccaaagaa gtcatcgatg cggcgcgcga agcggggttc aaatccgtca gcgtcgattt
     4021 gatttacggc ctgccgcacc agacttcgga aagcatcaaa accaccatcg ataccgtttt
     4081 gtcgctcgat cccgaccgcc tcgcccttta tcactacgcc cacctgccgc acgtgttcaa
     4141 accgcaacgc cgcatcgata ccgccgccgt tcccgacagc gaagagaagc tcgatatgct
     4201 gcaatactgc gtccaaaccc taaccgaacg cggctacgtc ttcatcggca tggatcattt
     4261 cgccaaacct gacgacgaac tctccatcgc cctcaaagaa ggcttcctcc agcgcaactt
     4321 ccaaggctat tcgacctacg cggattgcga tttggtcgcc atcggcgtgt cgtccatcgg
     4381 caaaatcggc agcacctatt cccaaaacga acgcgacatc gatgcctact atgccgccat
     4441 cgacgaaggc agactgccca tcatgcgcgg ttatcagctc aatcaggacg acatcctgcg
     4501 ccgcaacatc attcaggatt tgatgtgccg tttcgcgctc gactaccgga tttacgaaag
     4561 tatgttcggc atcccgttcg accgctactt caaagacgaa ctggcggatt tggaaaaact
     4621 cgccggtttg ggattggtgc gcctgaacag ccacgggctg accgttaccc cgaaaggacg
     4681 cttcctcatc cgcaacatcg ccatggtctt cgattaccac ctgcgccata aagaaaccaa
     4741 ggcgaaatat tcgcaaacgg tgtgattgcg tctaacgtac aaatgccgtc tgaaaggctt
     4801 tttcagacgg cattttgctg ccggcaggat aagtgttttc aagaacaggc ggcggcatat
     4861 cataacgttc cgcacctttg tgtccgaccg ttccgaaacc aagatatagt ggattaacaa
     4921 aaaccagtac ggcgttgcct cgccttgccg tactatttgt actgtctgcg gcttcgtcgc
     4981 cttgtcctga tttttgttaa tcactatacc aaacggcata tcccgacaga acagattgtg
     5041 cataaggcac aagcccgcac attccatcaa caaaatgccg tctgaacacg ggttcagacg
     5101 gcatcagtat tttacaatca gaatactgcc tgtaaaacca agtagcagac aaccgacaat
     5161 acggcggcgg caggcagggt aatgacccac gccaaaccga tgggcttcat cagtttccag
     5221 ttggcattgc ggttgaccag accgatgccg agtaccgcgc cgaccaagat atgcgtactg
     5281 gacacgggca gccccatcag cgacgcgccc atcacgacgg atgcggcgga cagttcggcg
     5341 gtaaaacccg aagcaggatg catttccgcc aaactcgtac cgacggtttt aatcacctct
     5401 ttaccgacaa accacaaacc gacaatcagc gcgataccga aagtcagcat cgcaatcggg
     5461 gggacgacat tttgcgcggc aacgctgttg gtacgcaaaa catccataat cgcggcaaac
     5521 ggaccgatgg cgttggcgat atcgttcgcc ccgtggctga atgcgaagcc gcaggcggta
     5581 aagacctgca tccatgaaaa catctgaaag gtcgatttgc ccaagtcttt acgcttgagg
     5641 cttttggcaa acacaaacgt ccccatccac accgccgcgc ctatcataaa gatggtcagg
     5701 aagctgttga cgttgctcat ccccaaatgc aggtttttca agcccttgaa aatcagcata
     5761 gcggaaatca tcatcgcgcc gaacgaagcg ataaagggaa tccaagaatg cagtgctttg
     5821 taggaatcga cattgttttt acggttgtcg aacgcataaa gaccgcggta atactccgat
     5881 tgcagctctt gcggatcgaa ttcgggttcg tcgtaaattt gcgcgtcgtg cgccattttg
     5941 gtggcgtact cgactttttc ggcttcggac aaaccctcga aaaacaggcg gtgccgttct
     6001 ttataggcct ttttttcctg cttgatgccc ttgagcgtgc cttccgccca agcgttgtaa
     6061 tctaagacgt ttttcttgac gcgcgaaaac aggaaatagg acaccgcgcc gcccaacacg
     6121 ggcgacaata cccaagaaac accaataccg cccagcttgc cccaacgtat caaatcgccc
     6181 gatgcggcat cgttcattac cgccatacat accgcgctgc cgacaatgcc gccgataatg
     6241 gaatgggtgg tagataccgg aagccctttt ttcgaggcaa acaacagcca caacgccgcc
     6301 gccaaaagcg cggacatcat aataaacaca aactgtatgg gttcgaaatc aacacccttc
     6361 aaatcgacga tgcctttgcg tatggtattg gttacctcgc cgcccgcgat gaccgcgccg
     6421 ctgacctcaa ataccgccgc aatcagcaaa gcctgcggga tggtcagcgt acccgcaccg
     6481 acgctggtgc cgaaagaatt ggcaacatcg ttgccgccga tgttgaacgc cataaacacg
     6541 ccgaacatcg tggcaataat gaataaggcg gcgtaattgt aatgggtata acccaagccc
     6601 caataaataa aatagccgac tgtacctacc agcatggcgg caaagacggc gttgatggtt
     6661 ttaacatttg cgctcatttg gatttgagcc atggcaatct tcctttaatg tggtggaaat
     6721 catgagtgtt gccgacactg tactgctgcc tccggtcgaa ctgccgtttc gggatatggc
     6781 agacgcatcc ttccttctga accgcatccg aataccccca aacctgaccg aatgcaaaac
     6841 tgctgccgga aacggtttgt atgacacttc tactactgga tgttgcgggc gcattataat
     6901 atttttccat ccgtcttgaa acatttattt acactttatt tacactgcgg cggcaaatcg
     6961 gtatacgagc gtcaatacac gttaaaatgg cgttttgcac cagtttggga gtgatgatgg
     7021 aaacacagct ttacatcggc atcatgtcgg gaaccagtat ggatggggcg gatgccgtgc
     7081 tggtacggat ggacggcggc aaatggctgg gcgcggaagg gcacgccttt accccctatc
     7141 ccgacaggct gcgccgccaa ttgctggatt tgcaggacac gggggcggac gaactgcacc
     7201 gcagcaggat tttgtcgcaa gaactcagcc gcctgtacgc gcaaaccgcc gccgaactgc
     7261 tgtgcagtca aaacctcgcg ccgtccgaca ttaccgccct cggctgccac gggcaaaccg
     7321 tccgacacgc gccggaacac ggttacagca tacagcttgc cgatttgccg ctgctggcgg
     7381 aactgactca gatttttacc gtcggcgact tccgcagccg cgaccttgcg gccggcggac
     7441 aaggtgcgcc gctcgtcccc gcctttcaca aagccctgtt ccgcgatgac aaagaaacac
     7501 gcgtggtact gaacatcggc gggattgcca acatcagcgt actcccctcc gacgcacccg
     7561 ccttcggctt cgacacaggg ccgggcaata tgctgatgga cgcgtggacg caggcacact
     7621 ggcagcttcc ttacgacaaa aacggtgcaa aggcggcaca aggcaacata ttgccgcaac
     7681 tgctcgacag gctgctcgcc cacccgtatt tcgcacaacc ccaccctaaa agcacggggc
     7741 gcgaactgtt tgccctaaat tggctcgaaa cctaccttga cggcggtgaa aaccgatacg
     7801 acgtattgcg gacgctttcc cgttttaccg cgcaaaccgt ttgcgacgcc gtctcacacg
     7861 cagcggcaga tgcccgtcaa atgtacattt gcggcggcgg catccgcaat cctgttttaa
     7921 tggcggattt ggcggaatat ttcggcacac gcgtttcctt acgcagcacc gccgaactga
     7981 agctcgatcc gcaatgggtg gaagcagccg catttgcgtg gttggcggcg tgttggatta
     8041 atcgcattcc cggtagttcg cacaaagcaa ccggcgcatc caaaccgtgt attctgggcg
     8101 cgggatatta ttattgagcg caaatgccgt ctgaaagccc gttccgccgt tcagacggca
     8161 ttttttcctc tttcgtttac aaacccttaa aatccattta cactcaaacc cgttcaaaac
     8221 aaaacaaacc ctgccatgaa aa
//
LOCUS       DAXIDM010000085         8149 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000085 DAXIDM010000000
VERSION     DAXIDM010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8149
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.085"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            15..887
                     /locus_tag="ACFOAE_001578"
     CDS             15..887
                     /locus_tag="ACFOAE_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885037.1"
                     /translation="MRNPLNVLVGILGNFAKVSNCEFWDKINYNRAAQAAEQRAKQAQ
                     ETPKEPPKQEEHFIAKLPNDKLMTIYRLFQKQLDDMRGLERDIERGDWYINARYRMNE
                     NRNKIRALEDDNKRLHHDYWAVQDQGENRFFGMGKIGAKLVKENEKQQHINERHGANV
                     REIRRLKTENEKLEGQYSDKLAADVVKVRDRFNEELDNVRREIGKRPMEEFRNVFLQA
                     AQEAQTTIGQKAVQIELEKFPLNGSPSAKRIAFYFGAQRIREVEQKEREDQRKEQERQ
                     ARRMERDDGHGIGM"
     gene            complement(1157..2419)
                     /locus_tag="ACFOAE_001579"
     CDS             complement(1157..2419)
                     /locus_tag="ACFOAE_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HFC6885038.1"
                     /translation="MTLFRPEVFQAKKNRWTGQIVLVRPFSLQFLTFFAVSLAAILVA
                     FLIFGSYTNKTTVTGQLLPTTGVVRVYSQDMGVIAHQHVMNGDFVKKGDVLFTLSTSR
                     NDNNGSIQARLLAEAELKKSLSEQEIIMKKRVHAAEKTAQENTVHRFQNQMQHVRNQI
                     IMQEKRIAISEKMLEKQRYLAKMDAISELEKNSYEIALLELKAGLAAYQREADNLARE
                     ITVQQSNLKNLPEQQATEISQLERAVSVYQQEILDYQQRNEQTIRATISGYVSSINTE
                     IGQQVDTNKLLMSIVPKESELLANLYVPSRAIGFVKPNDKVILRYQAYPYQKFGHAEG
                     HVISIAQTALGAQEWTNLGNIFTQTAQVNEPVYLIKVKLDNQHIRIYGTEKKLQIGMI
                     LEADILHENKRLYEWILDPLYQVMGKIS"
     gene            complement(2421..4517)
                     /locus_tag="ACFOAE_001580"
     CDS             complement(2421..4517)
                     /locus_tag="ACFOAE_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HFC6885039.1"
                     /translation="MPTYLSRLSFSFSRRLPVILQTEAAECGLACLVSVLGFHGFYTD
                     LRHLRARFSLSLKGATLADLVRFANSMNLTARAVRLDLDELANLRVPCILHWDLNHFV
                     VLHEVHRNHIMIMNPASGWQKVRMEEVSRCFTGVALELFPNTQFEEKHETRKIRVLPM
                     LRGVVGLKRSLFQLLLLAAVLQVFALASPFFMQWVIDHAIVSADRDLLMTLALCFGLL
                     MIVRQLVSLLQTWAGMYLSTSLNIQWKANVLRRLMDLPVSYFTKRHLGDVVSRFGSVD
                     SIQSTLTSTFFVLVLNSIMAVFTLGLMYLYSPSLTAVVLVVLLIYIGIRWVAYYPLRH
                     ATEENIVHAAKQSSYFMETIRGIQTVKLFDKNAQRHAAWLNLFVDTINTGLTTQKLSA
                     MFGFANSLLFGIANILIVYFGAVSVLDGVFTVGALMAFMSYKSQFESKAGSLIDQFVQ
                     IKMLGLHAERLADIVLEKTENEQNNDFRLPKNLEHFDIKIENISFRYAENEPYILQDF
                     SLIIKQGTAIAFAGHSGCGKSTLIQILTGSLKPESGHVLLGENDIHAFPPAFIRKWSA
                     SVMQDDVLFAGSIAENISFFDDTPNMEKIAFCAQMANIHHEIVAMPMAYETLIGDMGS
                     ALSGGQKQRIVLARALYREPKILFLDEASSHLDINNERVINDNLRQLNITKIMVAHRQ
                     ETLNTADSVVYLDKVA"
     gene            complement(4553..4888)
                     /locus_tag="ACFOAE_001581"
     CDS             complement(4553..4888)
                     /locus_tag="ACFOAE_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HFC6885040.1"
                     /translation="MKELTIQDLTLVSGGFEVGRDYIGVGSAVTTAGSVAGSIRAATM
                     TGDAAAIVTRSGLTAVRAGTVAIPVIAYNATVWVNNNTTLQDKLGSLIDKVTGLDQSG
                     NDYGDGTSY"
     gene            complement(4912..5124)
                     /locus_tag="ACFOAE_001582"
     CDS             complement(4912..5124)
                     /locus_tag="ACFOAE_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885041.1"
                     /translation="MFNFLNKNIFIKAIKVIVMGCFYSFLVFGLFVSGKEFGYPYAPN
                     MDAGGLAFLSVYIGFFLSVALHIYDI"
     gene            complement(5452..5787)
                     /locus_tag="ACFOAE_001583"
     CDS             complement(5452..5787)
                     /locus_tag="ACFOAE_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885042.1"
                     /translation="MYELSIVELELVSGAGPIADFTTGVGGAIGGGAGYIAGKAGGGT
                     IGGILGSPFGPGGTIVGVAAGQQYGGKVGSVIGAGAGSAIGGVIGRGIESILDNDRSG
                     NDYGDGTGY"
     gene            complement(6378..6713)
                     /locus_tag="ACFOAE_001584"
     CDS             complement(6378..6713)
                     /locus_tag="ACFOAE_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HFC6885043.1"
                     /translation="MKELNISDLKIVSGGAEPAYINPLDAIGIGSAAVGGGRAVSATA
                     TGDMIARSAARGGLIGLAGIAGWNTGTYLYHETPLGDWLSSGVDKLTGLDQNFNDASG
                     NDYGDGTGY"
     gene            complement(6955..8103)
                     /locus_tag="ACFOAE_001585"
     CDS             complement(6955..8103)
                     /locus_tag="ACFOAE_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFC6885044.1"
                     /translation="MHINFSMEYKEFNENYLYKKPFIFKKALDVSSISWKEINELYQR
                     ADPTDWQFKFRKGEIIPKEAYVESFNDVGRIRHRFNKTAVYQYLQDGATMVYNRIDNE
                     PFVDSIAKQIAQFAQAQTVVSGYLAFGSSSSYRNHWDTRDVFAVQLIGKKHWTISAPN
                     FDMPLYMQQAKDMPHITPSKTVDMEVILEAGDILYIPRGWWHNPMPMNCETFHLAIGT
                     FPPNGYNYMEWLMKKIPDIQSIRQNFIGWQHDQKNLDDAAQAITEMMNNPKNYQTFMQ
                     DFLGSQRTNTAFNMDLFGNAHNQTLPEHCFLRLNSNDCSTLPQGFLIVNGIKLNVDES
                     SMKFLTILVDKYMISLAEILLFFSVDEEENIKKLVWRLGELDIIEIIR"
BASE COUNT         2688 a         1683 c         1362 g         2416 t
ORIGIN      
        1 ggaagaaggt actcatgaga aatcccctaa atgtcttagt agggattttg gggaattttg
       61 caaaggtctc aaattgtgaa ttctgggata aaattaatta taatcgggct gcccaagccg
      121 ccgagcagcg ggcaaagcag gcgcaggaaa caccgaaaga gccgccgaaa caggaagagc
      181 actttatcgc caagctgccg aacgacaagc taatgacgat atacaggctg tttcaaaaac
      241 aactggacga catgcgcggc ttggagcgcg atatagaacg cggagattgg tacatcaatg
      301 cgcgataccg catgaacgaa aaccgaaaca aaataagggc gctggaagac gacaacaaac
      361 ggctgcatca cgactattgg gcagtccaag accaaggcga aaaccgcttt ttcggcatgg
      421 gtaaaatcgg cgcaaaactg gttaaggaaa acgagaagca gcaacacatc aacgaacggc
      481 atggagcgaa cgtgcgagaa atccggcggc tgaaaacaga aaacgaaaaa ctggaagggc
      541 agtatagcga caagttggcc gccgacgtgg tcaaagtacg cgacaggttt aacgaagaac
      601 tggacaatgt ccgcagggaa atcggcaaac ggccgatgga agaattcagg aacgtatttt
      661 tgcaggcagc ccaagaagca cagacgacaa tagggcagaa ggcggttcaa atcgaactgg
      721 aaaaattccc cctgaacggc agcccttcgg ccaagcgaat cgcgttttat ttcggcgcgc
      781 agcggataag ggaagtagag cagaaggagc gggaagacca gcgcaaagag caggagcggc
      841 aggcgcggcg tatggagcgg gacgacggcc acggcatcgg catgtagaaa aaccagccta
      901 tcatactggt tggaagacgt attatggtac aaagtcagca aatgcatcga aaatatttac
      961 ttctcgcata caacgcagat acaattgcag caattcagga agcaaaaatg gagcgaaaaa
     1021 ttgtatcact tctctgtctt cattattaca taaaacactg tgtatttgtg cttaacaaca
     1081 aattggaagt catcggacat tggttttgct tgataattag gggcactcat acgctccaat
     1141 gtattgagca attcagctat gatatttttc ccattacttg atacaaaggg tcaagtatcc
     1201 attcatataa ccgtttattc tcatgcaaaa tatcggcttc tagtatcata ccaatttgca
     1261 atttcttctc cgtgccatat atacgaatat gctgattatc cagttttact ttgattaaat
     1321 aaacaggctc attcacttgt gccgtttgag taaaaatatt gcctaaattt gtccattctt
     1381 gcgcccctag tgccgtttga gcaatagaaa tgacgtgtcc ttctgcgtgt ccgaattttt
     1441 gataaggata tgcttgataa cgcaaaatta ccttgtcatt tggttttaca aaaccgattg
     1501 cgcgactagg gacatataaa ttagccagta attcactttc tttcggcacg atactcatca
     1561 atagtttgtt agtatctacc tgctgaccaa tttccgtgtt aatagaactg acatagcctg
     1621 atatggttgc gcgaatagtt tgttcgttac gttgttgata atccaatatt tcttgttgat
     1681 agacagatac tgcgcgttct aattgactga tttcagtagc ttgctgttca ggcagatttt
     1741 ttagattgct ttgctgtaca gttatttccc gagcaagatt atctgcttct cgttggtaag
     1801 cggctaaacc tgctttcagc tccaataaag caatttcata actatttttt tctaattcag
     1861 aaattgcgtc cattttggct aaataacgct gtttttctaa cattttttca gaaatcgcaa
     1921 tacgtttttc ttgcatgata atttgatttc taacgtgttg catttggttc tgaaaacggt
     1981 gtaccgtgtt ttcttgtgcg gttttttctg ctgcatgaac acgttttttc ataataattt
     2041 cttgttctga tagtgatttt tttaattcag cttcggcgag taatcgtgct tgtatgctgc
     2101 cattattgtc atttcgtgaa gtagataatg taaataacac atcgcctttt ttcacaaaat
     2161 cgccattcat aacgtgttga tgagcaataa cccccatatc ctgcgaatat acgcgtacta
     2221 cccctgttgt cggcaaaagt tgtcctgtta cggtggtttt attggtatag ctcccaaaaa
     2281 ttaaaaaagc aactaaaata gccgctaatg agaccgcgaa aaatgttaaa aactgcaagg
     2341 aaaaaggacg cactaaaaca atttgccctg tccagcgatt ttttttagct tggaatactt
     2401 cggggcgaaa taatgtcatt tcaggctacc ttgtctaaat aaactacgct atcagcagta
     2461 tttaaagttt cctgacgatg cgcgaccatg attttggtaa tgttgagttg gcgtagatta
     2521 tcgttaatca cacgttcatt gttgatgtcc aaatggctac tggcttcgtc taaaaacaaa
     2581 attttgggtt cacgatataa agcacgagct agaacaatac gctgcttttg cccaccgctc
     2641 aatgcgcttc ccatgtcacc aattaaggtt tcatacgcca taggcatagc gacaatttca
     2701 tgatgaatat tcgccatttg agcgcaaaat gcgatttttt ccatattggg cgtatcatca
     2761 aaaaaactga tgttttctgc gattgagcca gcaaataaca catcatcttg cattacactt
     2821 gcgctccatt tgcggataaa tgcaggtgga aacgcatgaa tatcattctc gcctagtagc
     2881 acgtgaccgc tttcaggttt cagactgcct gtcagaattt gaatgagcgt agatttccca
     2941 cagcctgaat gtccagcaaa agcaatggct gttccttgtt tgataattaa actgaaatct
     3001 tgcaaaatgt atggttcatt ttcagcatag cgaaatgata tattttctat tttaatatca
     3061 aagtgttcta aatttttagg cagcctgaaa tcgttgttct gctcgttttc cgttttttct
     3121 agcacaatat ccgccaagcg ttccgcgtgc aatcctagca ttttgatttg tacaaactgg
     3181 tcaatcaatg aacctgcttt actctcaaac tgacttttgt aggacataaa cgccattaac
     3241 gccccaacgg taaaaacacc gtccaacaca gaaaccgcac caaaatacac aattaaaata
     3301 ttagcgatac caaacaaaag gctgttcgca aaaccgaaca ttgcggaaag tttttgtgtc
     3361 gttaaacctg tgttgattgt atcaacaaat aagttcagcc aagccgcatg acgttgtgca
     3421 tttttatcaa ataatttaac ggtttgaata ccgcgtatgg tttccatgaa ataactgctt
     3481 tgcttggcag catgaacaat attttcttcg gttgcatggc gtaacggata atatgccacc
     3541 caacgaatac cgatataaat cagtaaaaca accaatacaa cagccgttaa actagggctg
     3601 tataaataca ttaaccctaa tgtaaatact gccataatgc tgttgagtac cagcacaaag
     3661 aaagtagaag tgagcgtact ttgaatacta tccaccgagc caaaacgtga aaccacatcg
     3721 cccaagtgtc gtttagtgaa ataagaaaca ggcaaatcca ttaagcggcg taatacatta
     3781 gctttccatt gaatattcaa agaggtagat aagtacatac ccgcccaagt ttgcaacaat
     3841 gacactaact gccgcacaat catcaacaag ccaaaacaca atgccaatgt catcaataaa
     3901 tcacggtctg ccgatacaat ggcatggtct attacccatt gcataaaaaa agggcttgcc
     3961 aaagcaaaca cctgtaatac tgccgccagc agcagaagct gaaataaaga cctttttaat
     4021 cccaccactc cgcgcaacat cggtagtacg cgaattttac gcgtttcgtg tttctcttca
     4081 aattgcgtgt taggaaatag ttccaacgct acacctgtaa aacagcgcga gacttcttcc
     4141 atacgcactt tttgccaacc cgaagcaggg ttcataatca taatgtgatt gcgatgaact
     4201 tcatgcaaca ccacaaaatg atttaaatcc caatgcaaaa tacagggtac gcgcaaattt
     4261 gctaactcat ctaaatccaa ccgaacagcc cgagcggtta aattcatgct attagcaaac
     4321 cgtaccaaat ccgccaatgt tgcgccttta agcgacaaag aaaaacgcgc ccttaaatgg
     4381 cgcaaatccg tataaaaacc atgaaacccc aacaccgata ccaaacacgc taatccacat
     4441 tcggctgctt ccgtttgcaa aataacgggc aaacggcgcg agaaactgaa tgataggcga
     4501 gagagatatg ttggcattag agttcctatt ttatttgcaa aacattatgg gattagtaac
     4561 tagtcccatc accataatca tttcctgatt gatccaagcc agttacttta tctattaaac
     4621 tacctaattt atcttgtaat gtggtattgt tattaaccca tacagtagca ttataggcga
     4681 taactggaat agctactgtt ccagcacgca ctgctgttaa tcctgaacga gttacaattg
     4741 ctgcagcatc tccagtcatc gtagctgctc ttatagaacc ggcaacacta cctgctgtag
     4801 ttacagctga acctacacca atataatcac gaccaacctc aaatccaccc gaaactaggg
     4861 ttaaatcctg aatagttaat tctttcataa ttatttatcc tttcaattgt attaaatatc
     4921 gtaaatatgc aaagccacgc ttaaaaaaaa gccaatatat acactcaaaa aagcaagccc
     4981 acccgcatcc atattaggtg catatggata accaaattcc ttaccagata caaaaagacc
     5041 aaaaactaaa aatgaataaa aacagcccat tacaattact ttaattgctt taataaatat
     5101 attcttattt aaaaaattaa acataataat ttatcctttt aactttcaat taaacattcc
     5161 aatacatcaa ccattgtcaa tttaaacact aatttttcca ctttttccaa attggcgaaa
     5221 gagatatatt ggcattagag ttcctatttt attttttatt taaaaaaatt attattaccg
     5281 ataataatac tgataataaa aaaaataaaa ctattttcat ttgattacga cttaatggag
     5341 gctaatgtat taatccgtaa tgtacagata agccaaccaa aaaaatcaaa acaagaaaga
     5401 aagccatgag tacttggtaa ggattcatca atgctatccc tataattttg tttaataccc
     5461 tgttccatca ccgtaatcat tacctgatcg atcattatcc aaaatgcttt caatacctcg
     5521 tccgatcaca ccaccaatgg cagatccagc tcctgcccca attacagaac caaccttacc
     5581 accatattgt tgtccagctg caacaccaac tatagtacca cctggaccaa atggagagcc
     5641 tagaattccc ccgatggttc caccacctgc tttccctgca atatatccag caccaccacc
     5701 aatagcacct cccactcctg tagtgaaatc agcaatggga ccagcaccac taactaattc
     5761 aagttctaca atagagagtt catacatttt tatttacctc aaaataaatt taataataaa
     5821 aaagaaatga gttagacaga atagtatcac tataaaaatg atagaataaa tattcatatt
     5881 aaaataaaaa ttttcctgtc taaatagagt tattaaggca atatacaaaa taaccataaa
     5941 ataaaaagta aatattttta caaattctat tttattttga tttttattta ttcctcgtgc
     6001 aaaaattacc attttataaa tcaaaagcaa tgttgaaatt ataaacgaaa atgctattaa
     6061 tatagaaata tgatttacaa aaggtatagt tgataaatta aatctaactt tactgtatat
     6121 aatgtatacg ttcaataaaa taaatgatat tgaggatata ttgattaaaa tttttgtgtt
     6181 atttaataaa acacccattg attacctcac gatttcaata acatctaata aacataactc
     6241 cctaactaat ttcttaatat tttcttgttc atcaacacta aacaacgata atattcagct
     6301 agggatatca tgtaaagcaa gaaagaaagc catgagtact tggtaagcat tcatcaatgc
     6361 tattcctata attttgttta ataccctgtt ccatcgccat aatcattacc agatgcatca
     6421 ttaaaatttt ggtctagtcc tgttaattta tcaactcctg aacttaacca atcgcctaat
     6481 ggcgtttcat gatataaata agtacctgta ttccagcctg ctatgcctgc caaaccaatt
     6541 aatccacctc gagcagcact tcttgctatc atatccccag ttgcagtagc tgaaacagct
     6601 ctccctccac ctaccgctgc actacctata ccaatagcat caagaggatt aatgtaagct
     6661 ggttcagcac cacctgaaac tattttcagg tcagaaatat ttaattcttt cattgctttt
     6721 cctttttaac aatcttattt ttcaatatga ttgaatagta cgctcatgcc aataccaatc
     6781 ataatactaa atactatatt aatgtaatct ccgtcataat taggatgaag acgccaccct
     6841 cctaattctg ataatttcat aaaaatatat attacaatag aatatccaat tgcatgtaaa
     6901 aatgttttca tatattttat atcctaaaat attaaatcaa atattaaatc catctcatct
     6961 tataatttca attatatcta actctcctag ccgccaaact aatttcttaa tattttcttc
     7021 ttcatcaaca ctaaaaaaca ataatatttc agctagggat atcatgtatt tatcaaccaa
     7081 aatcgttaaa aatttcatac tactttcatc aacatttagc ttaataccat tcacgataag
     7141 aaatccttgt ggaagagttg agcaatcatt actatttaat cttaaaaagc aatgctcagg
     7201 taatgtctga ttatgagcat ttccaaacaa atccatattg aatgctgtat tggtacgctg
     7261 acttcccaaa aaatcttgca taaatgtttg ataatttttt gggttattca tcatttcggt
     7321 aattgcttga gctgcatcat ctaggttttt ttggtcgtgt tgccagccta tgaaattttg
     7381 acgaatactc tggatatcag gtattttttt catcaaccat tccatatagt tataaccgtt
     7441 tggcggaaat gtaccaatag ctaaatggaa tgtttcacaa ttcataggca taggattatg
     7501 ccaccaacca cgcgggatat atagaatatc tcctgcttct aaaatgactt ccatatccac
     7561 tgttttagat ggagtaatgt gcggcatatc ttttgcttgt tgcatataca atggcatatc
     7621 aaaatttggg gcagaaattg tccaatgttt tttgccaatc aattgtactg caaatacatc
     7681 tcgagtatcc caatgattac gatatgatga tgagctacca aacgctaaat aaccactaac
     7741 aacagtttgt gcttgagcaa actgggcaat ttgtttagca atactgtcaa caaatggctc
     7801 attatcaata cggttataaa ccattgttgc accatcttgc agatactgat atacggctgt
     7861 tttattaaac cgatgacgta ttctacccac atcattgaat gattcaacat aggcttcttt
     7921 ggggattatt tcccctttgc gaaatttaaa ttgccaatca gtagggtctg cacgttgata
     7981 caactcatta atttctttcc atgagataga acttacgtct aaagcttttt taaaaataaa
     8041 cggcttttta tataaataat tttcattaaa ttctttatat tccattgaaa agttaatatg
     8101 cacaaataat ccttattttc attattaata atgaaaatta agtttactt
//
LOCUS       DAXIDM010000086         8137 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000086 DAXIDM010000000
VERSION     DAXIDM010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8137
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.086"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(67..291)
                     /locus_tag="ACFOAE_001586"
     CDS             complement(67..291)
                     /locus_tag="ACFOAE_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SlyX family protein"
                     /protein_id="HFC6885045.1"
                     /translation="MDAVQELEHRITELEIQSALQEDVIAGLNAMVAELRQTLDLQQA
                     QLRLLYQKMQDRNPDAQEPYSLRDEIPPHY"
     gene            complement(292..1680)
                     /locus_tag="ACFOAE_001587"
     CDS             complement(292..1680)
                     /locus_tag="ACFOAE_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter family protein"
                     /protein_id="HFC6885046.1"
                     /translation="MNAVVVAVIVMLVLSLSRVHVVLSLTVGAFVGGAVAGMPLQNIA
                     DAAGQVSQAGIIPVFNKGLEGGAKIALSYAMLGAFAMAITHSGLPQQLAGAVVRKLNR
                     GGMPDSVRSGEGAVKWLLLSIILVMGMMSQNIIPIHIAFIPMIVPPLLLVFNRLKIDR
                     RLIACVITFGLVTTYMFLPYGFGAIFLNEILLGNIHSAAPQLDVKNINVMAAMAIPAL
                     GMLTGLLLAFVHYRKPRLYQSNNADTAGNADAANRPQPSAYRSLAAAAAIAVCFAIQL
                     MYEDSLVLGAMLGFAVFMMLGVINRDKANDVFGEGIKMMAMVGFIMIAAQGFAAVMNA
                     TGHIQPLVESSMAIFGNSKGMAALAMLVVGLLVTMGIGSSFSTLPIIAAIYVPLCVGL
                     GFSPLATVAIVGTAGALGDAGSPASDSTLGPTMGLNADGQHDHIRDSVIPTFIHYNIP
                     LLIAGWIAAMVL"
     gene            complement(1766..2587)
                     /gene="prmC"
                     /locus_tag="ACFOAE_001588"
     CDS             complement(1766..2587)
                     /gene="prmC"
                     /locus_tag="ACFOAE_001588"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFC6885047.1"
                     /translation="MTFDKWLGLSKLPKNEARMLLQYVSEYTRVQLLTRGGEEMPDEV
                     RQRADRLAQRRLNGEPVAYILGVREFYGRRFTVNPSVLIPRPETEHLVEAVLARLPEN
                     GRVWDLGTGSGAVAVTVALERPDAFVRASDISPPALETARKNAADLGARVEFAHGSWF
                     DTDMPSEGKWDIIVSNPPYIENGDKHLLQGDLRFEPQIALTDFSDGLSCIRTLAQGAP
                     DRLAEGGFLLLEHGFDQGAAVRGVLAENGFSGVETLPDLAGLDRVTLGKYMKHLK"
     gene            complement(2577..3038)
                     /locus_tag="ACFOAE_001589"
     CDS             complement(2577..3038)
                     /locus_tag="ACFOAE_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885048.1"
                     /translation="MQEQNRKSSFPIVMLLVSVALWIASLSNVAFYLGNHGSMEGLTV
                     LILGSIFASLDIRYCAVYANYVWLAAIVLLALRKKVVPVHAALWGLALVAFSVKAVYV
                     DEAGNTSDIVRYGAGFYLWYAAFAVATIGTFAGKNKERKAASAADGTKNDV"
     gene            complement(3104..4588)
                     /gene="tldD"
                     /locus_tag="ACFOAE_001590"
     CDS             complement(3104..4588)
                     /gene="tldD"
                     /locus_tag="ACFOAE_001590"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HFC6885049.1"
                     /translation="MPYNQAPDFLCADTMHPTYSAVQARLLEANRLSPELLAKSLCII
                     GAHHVDYADIYCQRTAYESWHLEEGIVKSGSFQIDQGVGVRAVSGDKTAFAYADSLCI
                     DSINRSARAVRAIGAAGGKVSAKMPSETRGKPVCSASDPIASLDSAAKVALLNKVETL
                     AKAADPRIVQVMAGLTCEYDMVYLARLDGKHAADIRPMVRLNVTVIAKQGERREQGSA
                     GGGGRYDLAYFDENLVRQFVDAAVKQALTNLESRPAPAGEMTVVLGNGWPGVLLHEAV
                     GHGLEGDFNRKGTSVFSGRIGERVAAKGVTVVDQGDIAGRRGSLNIDDEGNETRRTVL
                     IEDGILVGYMQDETNARLMGTQSTGNGRRESYASAPMPRMTNTFMENGGYEPEEIIAS
                     IDKGIYAVNFGGGQVDITSGKFVFSASEAWWVEGGKLQYPVKGATIIGNGPEVLKHVS
                     MIGNDTALDSGVGVCGKEGQSVPVGVGQPTLRIDAGLTVGGSAI"
     regulatory      4766..4869
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4936..6159
                     /gene="cytX"
                     /locus_tag="ACFOAE_001591"
     CDS             4936..6159
                     /gene="cytX"
                     /locus_tag="ACFOAE_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003519479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydroxymethylpyrimidine transporter
                     CytX"
                     /protein_id="HFC6885050.1"
                     /translation="MSGNASSPSSSAAIGLIWFGAAVSIAEISTGTLLAPLGWQRGLA
                     ALLLGHAVGGALFFAAAYIGALTGRSSMESVRLSFGKRGSVLFSVANMLQLAGWTAVM
                     IYAGATVSSALGKVLWDGESFVWWALANGALIVLWLVFGARKTGGLKTVSMLLMLLAV
                     LWLSAEVFSTAGSTAAQVSDGMSFGTAVELSAVMPLSWLPLAADYTRHARRPFAATLT
                     ATLAYTLTGCWMYALGLAAALFTGETDVAKILLGAGLGAAGILAVVLSTVTTTFLDAY
                     SAGASANNISARFAETPVAVGVTLIGTVLAVMLPVTEYENFLLLIGSVFAPMAAVLIA
                     DFFVLKRREEIEGFDFAGLVLWLAGFILYRFLLSSGWESSIGLTAPVMSAVAIATVLV
                     HLFFKKTQSLQRNPS"
     gene            6156..7256
                     /locus_tag="ACFOAE_001592"
     CDS             6156..7256
                     /locus_tag="ACFOAE_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFC6885051.1"
                     /translation="MTRIAILGGGLSGRLTALQLAEQGYQIALFDKGCRRGEHAVAYV
                     AAAMLAPAAEAVEATPEVIRLGRQSIPLWRGIRCRLNTHTMMQENGSLIVWHGQDKPL
                     SSEFVRHLKRGGVADDEIVRWRADDIAEREPQLGGRFSDGIYLPTEGQLDGRQILSAL
                     ADALDELNVPCHWEHECAPEDLQAQYDWLIDCRGYGAKTAWNQPPEYTSTLRGIRGEV
                     ARVYTPEITLNRPVRLLHPRYPLYIAPKENHIFVIGATQIESESQAPVSVRSGLELLS
                     ALYAVHPAFGEADILEIATGLRPTLNHHNPEIRYSLARRLIEINGLFRHGFMISPAVT
                     AAAVRLAVALFDGKDAPERDEESGLAYIRRQD"
     gene            7277..7894
                     /gene="thiE"
                     /locus_tag="ACFOAE_001593"
     CDS             7277..7894
                     /gene="thiE"
                     /locus_tag="ACFOAE_001593"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HFC6885052.1"
                     /translation="MTFPPLKSPLKFYAVVPTADWVGRMVKAGADTVQLRCKALHGDE
                     LKREIARCVAACQGSHTQLFINDHWREAIEAGAYGVHLGQEDMDTADLAAIAAAGLRL
                     GLSTHSVAELDRALSVHPSYIASGAIFPTTTKQMPTAPQGLDKLCEYVKQAGGTPVVA
                     IGGIDLNNARAVLATGVSSLAAVRAVTEAANPEAVVKAFQALWDG"
BASE COUNT         1754 a         2490 c         2191 g         1702 t
ORIGIN      
        1 ttaggtttgc atcggcggaa tattcaaaca cagccttttt taaggaaatc cggatacggc
       61 ggcgcatcaa taatgcggcg gaatttcatc gcgcagggaa tacggctctt gcgcgtcggg
      121 attcctgtcc tgcatttttt gatacagcag cctcaactga gcctgttgca aatccagcgt
      181 ctgccgcaat tccgccacca tcgcgttcag gccggcgatt acgtcctcct gaagcgcgga
      241 ttggatttcc agctctgtga tgcggtgttc caactcttga accgcgtcca tttacagcac
      301 catcgcggca atccagccgg caatcagcag cgggatgttg tagtggatga aggtcgggat
      361 aacggaatcg cggatgtggt cgtgctgccc gtcggcgttc agccccatcg tcggacccag
      421 cgtggaatcg gacgcaggcg aaccggcatc gcccaacgcc cccgccgtgc cgacaatggc
      481 gacggtggca agcggcgaaa aacccaaacc gacacacaaa ggcacataaa tcgcggcaat
      541 aatcggcaaa gtggaaaagg acgaaccgat gcccatcgtt accaaaagtc ccaccaccag
      601 catcgccaac gccgccatac ctttgctgtt gccgaatatc gccatactgc tttccaccag
      661 cggctgaata tgcccggtcg cattcatcac ggcggcaaaa ccctgcgcgg caatcataat
      721 gaagccaacc atcgccatca tcttgatgcc ttcgccgaat acgtcgtttg ccttgtcgcg
      781 gttgatgacg cccaacatca taaatacggc gaaaccgagc atcgcgccca acaccagcga
      841 gtcttcatac atcaactgga tggcaaaaca tacggcaatg gcggcggcgg cggccaggct
      901 gcggtaggcg gacggctgcg gacggtttgc cgcatcggcg ttgcccgccg tatcggcatt
      961 gttgctttgg tacaggcgcg gtttgcggta atggacaaac gccagcagga gtccggtcag
     1021 cattcccaac gcgggaatcg ccattgccgc cattacgttg atgtttttca catcaagctg
     1081 cggcgcggcg gaatggatgt tgcccaacag gatttcgttc aaaaaaatcg cgccgaagcc
     1141 gtaaggcagg aacatataag tcgtaaccag cccgaaagtg atgacgcacg caatcaggcg
     1201 gcggtcgatt ttcaggcggt tgaacaccaa aagcagcggc ggaacaatca tcgggataaa
     1261 ggcaatgtgg atggggatga tgttctgact catcatgccc atcacaagga tgatggaaag
     1321 cagcagccat ttgaccgcgc cctcgcccga acgcacgctg tcgggcatac cgccccggtt
     1381 cagtttgcgg acgaccgcgc cggcaagctg ctgcggcagg ccggaatggg taatcgccat
     1441 cgcaaacgca ccgagcatcg cataagaaag cgcaatcttc gcgccgcctt ccaaaccttt
     1501 gttgaacacg gggataatcc ccgcctgact gacctgtccc gccgcatcgg caatgttttg
     1561 cagcggcata cccgccaccg cgccgccgac aaacgcgccg accgtcaggc tcaataccac
     1621 gtgcacgcgc gacagcgaca gcaccagcat aacgattacg gcaactacga ctgcattcat
     1681 tgtttatcgc tccaaaccta taaatgttta catatcgaaa cacatcataa cccaataacg
     1741 gaaaacccgc caattttgca aacaattatt tcaaatgctt catatacttc cccagcgtaa
     1801 ccctgtccaa acccgccaag tccggcaggg tttccactcc cgaaaaacca ttctccgcca
     1861 acacgccgcg caccgccgcg ccctgatcga aaccgtgttc caacaacaaa aaaccgcctt
     1921 ccgccaaacg gtcgggcgcg ccttgcgcca aggtgcggat gcagcttagg ccgtctgaaa
     1981 agtcggtcag cgcgatttgc ggctcaaacc gcaaatcgcc ttgcaacaaa tgtttatcgc
     2041 cgttttcgat atagggcggg ttggacacga tgatgtccca tttcccttca gacggcatat
     2101 cggtgtcgaa ccacgaaccg tgtgcaaatt cgacccgcgc gcccaaatcc gccgcatttt
     2161 tccgcgccgt ttcaagggcg ggcgggctga tgtcggatgc gcgcacaaac gcatcggggc
     2221 gttcgagcgc gacggttacg gcaaccgcgc cgctgcccgt ccccaaatcc cacacgcgcc
     2281 cgttttcggg caggcgcgcc aatacggctt cgaccaaatg ttcggtttcg gggcgcggaa
     2341 tcagcacgct cggattgact gtaaagcgtc tgccataaaa ttcgcgcaca cctaaaatat
     2401 aggcaaccgg ctcgccgttc agacgacgtt gcgccagcct gtccgcccgc tgtcggactt
     2461 cgtccggcat ttcttccccg ccccgcgtca acaactgcac gcgcgtatat tccgaaacat
     2521 attgcagcag cattcttgct tcatttttag gcagttttga caagcccaac catttatcaa
     2581 acgtcatttt tcgtcccgtc tgccgctgat gcggcttttc tttccttatt ctttccggca
     2641 aacgtaccga tggtggcaac cgcaaatgcg gcataccaca aataaaatcc tgcaccgtag
     2701 cgcacaatat ccgatgtatt ccctgcttca tcgacgtata cggctttcac actgaaagcc
     2761 accaacgcca agccccaaag tgccgcatgg acaggcacga ccttcttccg caacgccagc
     2821 aaaacaatgg ccgccaacca aacataattc gcatagaccg cacaatacct gatatccaaa
     2881 gaagcaaata tcgaccccaa aatcaaaacg gtcaaaccct ccatgcttcc atgattgccc
     2941 aaataaaatg caacattgga taaagacgct atccacaggg caaccgacac cagcaacatc
     3001 actatgggaa aacttgattt ccgattctgt tcctgcatgg ttttatccta atgtaaaagg
     3061 ccgtctgaaa aaactttcag acggcatcgt gtcggattca gcgtcagatt gcgctgccgc
     3121 cgacggtcag cccggcatcg atacgcaaag tcggctgccc cacgccgacg gggacgctct
     3181 gcccttcttt gccgcacacg ccgacaccgc tgtccaacgc ggtatcgttg cctatcatgg
     3241 aaacatgttt cagcacttcg gggccgttgc cgatgatggt cgcgcctttg acgggatatt
     3301 gcagtttgcc gccttcgacc caccacgctt cggatgcact gaacacaaac ttgccgctgg
     3361 tgatgtccac ttgtccgccg ccgaagttga cggcgtaaat gcccttgtcg atggacgcaa
     3421 tgatttcttc cggctcatag ccgccgtttt ccataaaggt attggtcatg cgtggcatag
     3481 gggcggaagc gtaactttcg cggcggccgt tgccggtcga ttgcgtaccc atcagacggg
     3541 cgttggtttc gtcctgcata tagccgacta aaatgccgtc ttcaatcaat acggtgcggc
     3601 gggtttcgtt gccttcgtcg tcgatgttga gcgaaccgcg ccggccggca atatcgccct
     3661 gatcgacgac ggtaacgcct ttggcggcga cgcgctcgcc tattctgccg gaaaagacgc
     3721 tggtcccctt gcggttgaaa tcgccttcca aaccgtgtcc gaccgcttcg tgcagcaaca
     3781 cgcccggcca gccgttgccc aaaacgacgg tcatttcgcc ggcgggcgcg gggcgggatt
     3841 cgaggttggt gagtgcctgt ttgacggcgg catcgacaaa ctgccgcacc aagttttcat
     3901 cgaaataagc caagtcgtag cgtccgccgc cgcccgcgct gccctgttcg cggcgttcgc
     3961 cctgtttggc gatgacggta acgttcaggc gcaccatcgg gcggatgtcg gcggcgtgtt
     4021 tgccgtccag acgggcgagg taaaccatat cgtattcgca ggtcaaaccc gccatcactt
     4081 gcacgatgcg cggatcggcg gctttggcga gcgtttccac tttgttcaac agcgcgactt
     4141 tggcagcgga atcaaggctg gcaatggggt cggacgcgga acaaaccggc ttgccgcgcg
     4201 tttcagacgg cattttggcg gacaccttgc cgcctgccgc cccaatcgcg cggacggcgc
     4261 gggcggaacg gtttatcgaa tcgatgcaca ggctgtcggc gtaggcaaag gcggttttgt
     4321 cgcccgaaac ggcgcgcacg cccacgccct gatcgatttg gaagctgccc gatttgacga
     4381 tgccctcttc caaatgccag ctttcatagg cggtgcgctg gcagtagatg tcggcgtaat
     4441 cgacgtggtg cgcgccgatg atgcacaggc ttttggcgag cagttcgggg gaaaggcggt
     4501 tggcttcgag cagccgcgcc tgtacggcgg aataggtcgg atgcatagtg tcggcgcata
     4561 aaaaatcagg ggcttgatta tacggcattt gttatatagt ggattaacaa aaaacagtac
     4621 ggtgttgcct cgccttgccg tactatttgt actgtctgcg gcttcgtcgc cttgtcctga
     4681 tttttgttaa tccactatag aaatgcgccg tgccgcctga aatgtaagat ttttgccaac
     4741 gccccctgct tttgtgtaca cttaaagctc cttgtcggag tgccgccgcc gggcggctga
     4801 gattgcgaaa gcagaatccg tagaacctgt cggggtaatg cctgcgtagg aaacaaaccg
     4861 tcaaatgcct tatcaggctt ccgttccctt ttccgcactt ccccgcccac cttccttctt
     4921 tttaaaggac gtcatatgtc gggcaatgcc tcctctcctt catcttccgc cgccatcggg
     4981 ctgatttggt tcggcgcggc ggtctcgatt gccgaaatca gcacgggtac gctgcttgcg
     5041 cctttgggct ggcaacgcgg tctggcggct ctacttttgg gtcatgccgt cggcggcgcg
     5101 ctgttttttg cggcggcgta tatcggcgca ctgaccggac gcagctcgat ggaaagcgtg
     5161 cgcctgtcgt tcggcaaacg cggttcagtg ctgttttccg tggcgaatat gctgcaactg
     5221 gccggctgga cggcggtgat gatttacgcc ggcgcaacgg tcagctccgc tttgggcaaa
     5281 gtgttgtggg acggcgaatc ttttgtctgg tgggcattgg caaacggcgc gctgattgtg
     5341 ctgtggctgg ttttcggcgc acgcaaaaca ggcgggctga aaaccgtttc gatgctgctg
     5401 atgctgttgg cggttctgtg gctgagtgcc gaagtctttt ccacggcagg cagcaccgcc
     5461 gcacaggttt cagacggcat gagcttcgga acggcagtcg aattgtccgc cgtcatgccg
     5521 ctttcctggc tgccgcttgc cgccgactac acgcgccacg cgcgccgccc gtttgcggca
     5581 accctgacgg caacgctcgc ctacacgctg accggctgct ggatgtatgc cttgggtttg
     5641 gcagcggctc tgtttaccgg agaaaccgac gtggcaaaaa tcctgctggg cgcaggtttg
     5701 ggtgcggcag gcattttggc ggtcgtcctc tccaccgtta ccacaacgtt tctcgatgcg
     5761 tactccgccg gcgcgagtgc aaacaatatt tccgcgcgtt ttgcggaaac acccgtcgct
     5821 gtcggcgtta ccctgatcgg cacggtgctt gccgtcatgc tgcccgttac cgaatatgaa
     5881 aacttcctgc tgcttatcgg ctcggtattt gcgccgatgg cggcggtttt gattgccgac
     5941 tttttcgtct tgaaacggcg tgaggagatt gaaggctttg actttgccgg actggttctg
     6001 tggctggcgg gcttcatcct ctaccgcttc ctgctctcgt ccggctggga aagcagcatc
     6061 ggtctgaccg cccccgtaat gtctgccgtt gccattgcca ccgtactggt gcaccttttc
     6121 tttaaaaaaa cccaatcttt acaaaggaac ccgtcatgac ccgtatcgcc atcctcggcg
     6181 gcggcctctc gggaaggctg accgcactgc agcttgcaga acaaggttat cagattgcac
     6241 ttttcgacaa aggctgccgc cggggcgaac acgccgtcgc ttatgttgcc gccgccatgc
     6301 tcgcgcctgc ggcggaagcg gtcgaagcca cgcctgaagt catcaggctg ggcaggcaga
     6361 gcattccgct ttggcgcggc atccgatgcc gtctgaacac gcacacgatg atgcaggaaa
     6421 acggcagcct gattgtgtgg cacgggcagg acaagccatt atcgagcgag ttcgtccgcc
     6481 atctcaaacg cggcggcgta gcggatgacg aaatcgtccg ttggcgcgcc gacgacatcg
     6541 ccgaacgcga accgcaactc ggcggacgtt tttcagacgg catctacctg ccgaccgaag
     6601 gccagctcga cgggcggcaa atattgtctg cacttgccga cgctttggac gaactgaacg
     6661 tcccttgcca ttgggaacac gaatgtgccc ccgaagacct gcaagcccaa tacgactggc
     6721 tgatcgactg ccgcggctac ggcgcaaaaa ccgcttggaa ccaacctccc gaatacacca
     6781 gcaccttgcg tggcatacgc ggcgaagtgg cgcgggttta cacacccgaa atcacgctca
     6841 accgccccgt gcgcctgctg cacccgcgtt atccgctcta catcgccccg aaagaaaacc
     6901 acatcttcgt catcggtgcg acccaaatcg aaagcgaaag ccaagccccc gtcagcgtgc
     6961 gttccgggct ggaactctta tccgcactct atgccgtcca ccccgctttc ggcgaagccg
     7021 acatcctcga aatcgccacc ggcctgcgcc ccacgctcaa ccaccacaac cccgaaatcc
     7081 gttacagcct cgcccgacgc ctgattgaaa tcaacggcct tttccgccac ggcttcatga
     7141 tttcccccgc cgtaaccgcc gccgccgtca gattggcagt ggcactgttt gacggaaaag
     7201 acgcgcccga acgtgatgaa gaaagcggtt tggcgtatat ccgaagacaa gattaaagcc
     7261 gtctgaaagg aaccccatga ccttcccgcc actcaaatcc ccgctcaaat tctacgccgt
     7321 cgtccccacc gccgattggg tggggcgcat ggtcaaagca ggtgccgaca cggtgcaact
     7381 gcgctgcaag gccctgcacg gcgatgaatt gaaacgcgaa atcgcccgct gtgtcgccgc
     7441 ctgtcagggc agccatacgc agcttttcat caatgaccac tggcgcgagg caatcgaagc
     7501 aggcgcgtac ggcgtgcatc tcggacaaga agacatggac accgccgacc ttgccgccat
     7561 cgccgccgcc ggtttgcgct tgggtttgag tacgcactcc gttgccgaac tcgaccgcgc
     7621 cctgtccgta caccctagct acatcgccag cggcgcgatt ttcccgacca cgaccaagca
     7681 aatgcccacc gccccgcaag gcttggacaa actgtgcgag tatgtgaaac aggcaggtgg
     7741 cacgcccgtc gtcgccatcg gcggtatcga cttgaacaac gcccgagccg tactcgccac
     7801 cggcgtttcc tcactcgccg ccgtccgcgc cgtaaccgaa gcggcaaatc ccgaagcggt
     7861 ggttaaagcg tttcaggctt tgtgggatgg ataaaaccga aagaagaaaa ttcaattgcc
     7921 gtgtaggcaa aacttagccc gttatcgcaa acatacttaa ctttaaatgt ggcatatcat
     7981 caaattccgt cattcccgcg taagcgggaa tccgctttaa aacttgagaa accatcattt
     8041 gaaaaacagt ttccgaattt caaaaatgga ttcccgcctg cgcgggaatg acggcaactg
     8101 gccggttgcg tatcaaaaaa taaagtaatt cggctag
//
LOCUS       DAXIDM010000087         8065 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000087 DAXIDM010000000
VERSION     DAXIDM010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 8065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8065
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.087"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            108..1049
                     /gene="miaA"
                     /locus_tag="ACFOAE_001594"
     CDS             108..1049
                     /gene="miaA"
                     /locus_tag="ACFOAE_001594"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFC6885053.1"
                     /translation="MPTPKAFALLGPTAGGKTALALKIAETLPVEIISLDSALVYTGM
                     DIGTAKPSASERAFVPHHLIDIITPVQTYSAARFVEDCTRLVGEISSRGRFALIVGGT
                     MMYFRALTQGLNDLPEADACLRADLDEQKQMYGLDFLYRTLQQVDPETACRLKPNDSQ
                     RIGRALEVYYLTGKPMSTHLGSPTSHTLPFDLHTAALIPENRARLHENIALRFHLMLE
                     QGFIGEVENLRRLYPSLTADSPAIRCVGYRQAWEYLDGKTDFPAFVEKGIAATRQLAK
                     RQLTWLRKTPLDCVTDPFSDGNSCTRLIEAAKRFFGA"
     gene            1053..1772
                     /gene="tadA"
                     /locus_tag="ACFOAE_001595"
     CDS             1053..1772
                     /gene="tadA"
                     /locus_tag="ACFOAE_001595"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFC6885054.1"
                     /translation="MLTTPPLAPKTVAALHRLGIRTLEELRQNGAVQTFLLLKASGLT
                     LTKSTLWQLQSLLDGTPPQEMAQHDKTRLLAELKNHPPVAAFPPQGEMAHFMGLALEQ
                     AKLSALMGEIPVGAVIVSDGKIIASAHNTCIADCNVSRHAEINALAQAGSEMQNYRLD
                     GCDIYITLEPCAMCASALIQARIRRVIYGAAEPKTGAAGSIVNLFADKRLNTHTAIRG
                     GILQEECRAVLSRFFQNKRKG"
     gene            1777..2265
                     /locus_tag="ACFOAE_001596"
     CDS             1777..2265
                     /locus_tag="ACFOAE_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF456 domain-containing protein"
                     /protein_id="HFC6885055.1"
                     /translation="MTALLVILALALIAAGTAGIVYPALPGLALMFAGTWLLAYSGGY
                     QIYGAGVLWTVGLISLAGILADYVAGIWGTKYTGAGKLAVRGALAGSIIGIFFSLPGL
                     ILGPFIGAAAGELIDRRNMLQAGKAGLGTLLGLIVGTTFKIGCAVSILFILLVKYIAY
                     LF"
     gene            2331..3083
                     /gene="rlmB"
                     /locus_tag="ACFOAE_001597"
     CDS             2331..3083
                     /gene="rlmB"
                     /locus_tag="ACFOAE_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFC6885056.1"
                     /translation="MANQRPIYGFHAVNARLWQNPKSIVELYVQEGKNDVRTREVLEK
                     AANENIRVYFADADRLNAISKGARHQGVVGFIDASKNHVHLEDVLENLSEPPLLLILD
                     GITDPHNLGACLRTADAMGVHAVIAPKDKSAGLNATVSKVASGAAETVPYITVTNLAR
                     TLRELKEYGIWIIGTDMGGNADLYHCDLPDSAAWVMGNEGDGMRRLTREHCDMLVSIP
                     MFGTVESMNVSVSAGMVLSETRRQRVLKNEKA"
     gene            complement(3145..4536)
                     /locus_tag="ACFOAE_001598"
     CDS             complement(3145..4536)
                     /locus_tag="ACFOAE_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFC6885057.1"
                     /translation="MSGHMGKGADAPDLVYGLEDRPPFGNALLSAVTHLLAIFVPMIT
                     PALIVGGALELPVEMTAYLVSMAMVASGVGTYLQVNRFGPVGSGMLSIQSVNFSFVTV
                     MIALGAGMKEGGLTKDAMISTLLGVSFVGAFLVCFSAWLLPYLKKVITPTVSGVVVML
                     IGLSLVHVGITDFGGGFGAKADGTFGSMENLGLASLVLLIVLVFNCMKNPLLRMSGIA
                     VGLIAGYIVALFLGKVDFSALQNLPLVTLPVPFKYGFAFDWHAFIVAGAIFLLSVFEA
                     VGDLTATAMVSDQPIEGEEYTKRLRGGVLADGLVSVIATALGSLPLTTFAQNNGVIQM
                     TGVASRHVGKYIAVILVLLGLFPVVGRAFTTIPSPVLGGAMVLMFGLIAIAGVRILVS
                     HGIRRREAVIAATSVGLGLGVAFEPEVFKNLPVLFQNSISAGGITAVLLNLVLPEDKT
                     EAAVKFDTDHLEH"
     gene            complement(4551..4805)
                     /locus_tag="ACFOAE_001599"
     CDS             complement(4551..4805)
                     /locus_tag="ACFOAE_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885058.1"
                     /translation="MLPIVAYFTAGVKSGGSGMHGAAWRRMRRVCIFVFEIRLLRFAN
                     DIPAATVRNLFAGRARMPSEIEIEAVWRIRYNPRFGFFNI"
     gene            4843..5718
                     /gene="dapA"
                     /locus_tag="ACFOAE_001600"
     CDS             4843..5718
                     /gene="dapA"
                     /locus_tag="ACFOAE_001600"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFC6885059.1"
                     /translation="MLQGSLVALITPMNQDGSIHYEQLRDLIDWHIENGTDGIVAVGT
                     TGESATLSVEEHTAVIEAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEKAGADYTLS
                     VVPYYNKPSQEGMYRHFKAVAEAAAIPMILYNVPGRTVVSMTNDTILRLSEIPNIVGV
                     KEASGNVGSNIELINRAPEGFVVLSGDDHTALPFMLCGGHGVITVAANAAPKLFADMC
                     RAALQGDIALARKLNDRLIPIYDTMFCEPSPAAPKWAVSALGRCEPHVRLPLVPLTEG
                     GQAKVRAALKASGQL"
     gene            5727..6923
                     /gene="bamC"
                     /locus_tag="ACFOAE_001601"
     CDS             5727..6923
                     /gene="bamC"
                     /locus_tag="ACFOAE_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HFC6885060.1"
                     /translation="MPSEPFGRHNATNTLISITQDDTMTHIKPVIAALALIGLAACSG
                     SKTEQPKLDYQSRSHRLIKLEVPPDLNNPDQGNLYRLPAGSGAVRASDLEKRRTPAVQ
                     QPADAEVLKSVKGVRLERDGSQRWLVVDGKSHAEIWPLLKAFWQENGFDIKSEEPAIG
                     QMETEWAENRAKIPQDSLRRLFDTVGLGGIYSTGERDKFIVRIEQGKNGVSDIFFAHK
                     AMKEVYGGKDKDTTVWQPSPSDPNLEAAFLTRFMQYLGVDGQQAENASAKNPTLPAAN
                     EMARIEGKSLIVFGDYGRNWRRTALALDRIGLTVVGQNTERHAFLVQKAPNESNAVTE
                     QKPGLFKRLLGKGKAEKPAEQPELIVYAEPVANVSRIVLLNKDGSAYAGKDASALLGK
                     LHSELR"
     gene            complement(6980..7912)
                     /gene="pip"
                     /locus_tag="ACFOAE_001602"
     CDS             complement(6980..7912)
                     /gene="pip"
                     /locus_tag="ACFOAE_001602"
                     /EC_number="3.4.11.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0030163 - protein catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl aminopeptidase"
                     /protein_id="HFC6885061.1"
                     /translation="MYEIKQPFHSGYLQVSEIHQIYWEESGNPDGVPVIFLHGGPGAG
                     ASPECRGFFNPDVFRIVIIDQRGCGRSRPYACAEDNTTWDLVADIEKVREMLGIGKWL
                     VFGGSWGSTLSLAYAQTHPERVKGLVLRGIFLCRPSETAWLNEAGGVSRIYPEQWQKF
                     VAPIAENRRNRLIEAYHGLLFHQDEEVCLSAAKAWADWESYLIRFEPEEVDEDAYASL
                     AIARLENHYFVNGGWLQGDRAILNNIGKIQHIPTIIVQGRYDLCTPMQSAWALSKAFP
                     EAELRVVQAGHRAFDPPLADALVQAVEDIFPRLL"
BASE COUNT         2058 a         2648 c         1892 g         1467 t
ORIGIN      
        1 ggcatacggt aaacacgccc ccttgccgtc ggcgtgcttc cgcaaaccaa aatataacgt
       61 cggcacgctt tccgctataa tccgcatttt cgcaaccctg aaacatcatg ccgaccccga
      121 aagcctttgc cctgctcggg ccgaccgccg gaggcaaaac cgcgctcgcc ctcaaaattg
      181 ccgaaaccct gcctgtcgaa atcatcagcc tcgattccgc gctggtctat accggtatgg
      241 acatcggcac ggcgaaaccg tccgcctccg aacgcgcctt tgtcccgcac caccttatcg
      301 acatcattac gcctgttcag acatacagtg ccgcccgttt tgtcgaagac tgcacgcgct
      361 tggtcgggga aatttcctca cgcggcaggt ttgcccttat tgtcggcggc acaatgatgt
      421 atttccgcgc cctgacccaa ggtttgaacg atttgcccga agccgatgcc tgcctgcgtg
      481 ccgacttgga cgaacaaaaa caaatgtacg gcttggattt cctctaccgc accctgcaac
      541 aggtcgaccc tgaaacagca tgccgtctga aaccgaacga cagccagcgt atcggacgcg
      601 ctttggaagt ttattattta accggcaaac cgatgagtac gcatctcggc agcccaacct
      661 cccatacgct ccccttcgat ttgcataccg ccgccctgat tcccgaaaac cgcgcccgcc
      721 tgcatgaaaa catcgccctg cgtttccacc tgatgcttga acagggcttt atcggcgaag
      781 tagaaaacct gcgccgcctc tatcccagcc tgaccgccga ctcccctgcc atacgctgcg
      841 tcggctaccg tcaggcatgg gaatatctgg acggaaaaac cgatttcccg gcatttgtcg
      901 agaaaggcat tgccgccacg cgccaacttg ccaaacgcca actgacttgg ttgcgcaaaa
      961 cacctttaga ctgcgttacc gacccgtttt cagacggcaa ttcatgcaca cgcctgattg
     1021 aggcggcaaa acggtttttc ggcgcataaa ctatgctgac cacgccgccg ctcgccccca
     1081 aaaccgtcgc cgccctacac aggctcggta tccgtacgct cgaagaactg cggcaaaacg
     1141 gcgcggttca aaccttcttg ttattgaagg catcaggttt gaccctcacg aaaagcacgc
     1201 tgtggcagct tcagtcgctg ctggacggca cgccgccgca agaaatggcg caacacgata
     1261 aaacccgcct gcttgccgag ttgaaaaacc atccgcccgt cgccgccttt cccccgcaag
     1321 gcgaaatggc gcatttcatg ggtttggcat tggaacaggc gaaactgtcc gcattaatgg
     1381 gcgaaatacc cgtcggggca gtcatcgttt cagacggcaa aatcatcgca tcggcacaca
     1441 acacctgcat tgccgactgc aatgtcagcc ggcacgccga aatcaacgcc ttggcacagg
     1501 caggcagcga aatgcaaaac taccgccttg acggatgcga catctacatc accctcgaac
     1561 catgcgccat gtgcgcgtcc gcactgatac aggcacgaat caggcgcgtg atctacggtg
     1621 cggcagaacc caaaaccggc gcggcaggaa gcatcgtcaa cctgtttgcc gacaaacgcc
     1681 tcaatacgca caccgccata cggggcggaa tcctgcaaga agaatgccgc gccgtattaa
     1741 gccgtttttt ccaaaacaaa agaaaaggtt gaacctatga ccgccttgct cgtcatcctc
     1801 gccctcgccc tgatagccgc cggtacggcg ggcatcgttt accccgccct gcccggattg
     1861 gcattgatgt ttgccggaac ctggctgctc gcctactccg gcggctacca aatctacggc
     1921 gcgggcgttt tgtggacggt cggactcatc agccttgccg gcatactggc ggactatgtg
     1981 gcaggcatat gggggacaaa atataccgga gcgggcaagc tcgccgttcg cggcgcattg
     2041 gccggcagca tcatcggcat atttttctcc cttcccggac taatactcgg tccctttatc
     2101 ggcgcggcgg caggcgaact gatcgatcgg cgcaatatgc ttcaggcagg taaagcgggc
     2161 ttgggtacgc tgttggggct tatcgtcggt acgacattca aaatcggctg cgccgtatcc
     2221 atcttgttta tcctgttggt gaaatacatc gcctacctgt tttaacccct tcagacggca
     2281 taccggcaaa ttgctataat gccgtctgaa cccttttcac aaagcaccat atggcaaacc
     2341 aaagacctat ctacggcttc catgccgtca acgcccgatt gtggcaaaac cccaaatcca
     2401 tcgtcgaact ctatgtccaa gaaggcaaaa acgatgtacg cacgcgcgaa gtgttggaaa
     2461 aggcggcaaa cgaaaacatc cgcgtatatt ttgccgatgc cgaccgcctc aacgccatca
     2521 gcaaaggtgc gcgccatcag ggcgtggtcg gatttatcga tgcctccaaa aaccacgtcc
     2581 acctcgaaga cgtattggaa aacttaagcg aaccgccgct gctgctgata ctcgacggca
     2641 tcaccgatcc gcacaacctc ggcgcgtgcc tgcgtaccgc cgacgcaatg ggcgtacatg
     2701 ccgtcatcgc accgaaagac aaaagcgcgg ggctgaacgc caccgtcagc aaagtcgcca
     2761 gcggcgcggc ggaaaccgtc ccctacatca ccgtaaccaa cctcgcccgc accctgcgcg
     2821 agctgaaaga atacggcatt tggatcatcg gcaccgatat gggcggcaac gccgaccttt
     2881 accattgcga tctgcccgac agcgcggcat gggtgatggg caacgaaggc gacggtatgc
     2941 gccgcctgac acgcgaacat tgcgacatgc tggtgtccat acccatgttc ggcacggtcg
     3001 aaagcatgaa cgtctccgtg tctgccggaa tggtattaag cgaaacccgc cggcagcgcg
     3061 tattaaaaaa cgaaaaagcg taagcctcaa aaacaatgcc gtctgaaaca gggattctgt
     3121 ttcagacggc attcgttttc aaaatcagtg ttccaagtgg tcggtatcaa acttgaccgc
     3181 cgcctcggtt ttatcttcgg gcaagaccaa attcagcaag actgccgtaa tgccgccggc
     3241 ggaaatagag ttttggaaca agacgggcag gtttttaaac acttccggct caaacgcgac
     3301 acccaagccc aaaccgaccg acgttgccgc aattaccgcc tcgcgcctgc ggatgccgtg
     3361 gctgaccaaa atccgcacgc ccgcaatcgc aatcaagccg aacatcaaaa ccatcgcgcc
     3421 gcctaaaacc ggactcggaa tcgtcgtaaa cgcgcgtccg acaacgggga acagacccaa
     3481 cagcaccaaa atcacggcaa tatatttgcc cacatgacgc gaagccacgc cggtcatctg
     3541 aatcacgccg ttgttttgcg caaacgtcgt cagcggcagc gaacccaaag ccgtcgcaat
     3601 caccgacacc aagccgtcag ccaacacgcc gccgcgcaaa cgtttggtgt attcctcgcc
     3661 ttcaatcggc tggtcggaca ccattgccgt cgccgtcaaa tcgccgaccg cctcaaacac
     3721 gctcaacagg aaaatcgcac ccgccacaat aaatgcgtgc cagtcaaaag caaaaccata
     3781 tttaaacggt acgggcagcg taaccagcgg caggttttgc agtgccgaaa aatccacctt
     3841 gcccaaaaac agcgcgacga tatagccggc aatcagaccg accgcaatgc cgctcatccg
     3901 cagcagcggg tttttcatgc aattgaacac cagcacaatc agcagcacca gcgatgccag
     3961 ccccaagttt tccatcgagc cgaacgtgcc gtccgccttt gcgccgaagc cgccgccgaa
     4021 atcggtaata ccgacgtgta ccaaactcaa gccgatcagc atcaccacca caccgctgac
     4081 cgtcggcgta atcacttttt tcaaatacgg cagaagccac gccgaaaaac acaccaaaaa
     4141 cgcgccgaca aacgatacgc ccaagagcgt cgaaatcatc gcatccttag tcaaaccgcc
     4201 ctctttcatc cccgcgccga gcgcaatcat gacggtaacg aacgagaaat tcaccgactg
     4261 gatggacagc atccccgaac cgaccggccc gaagcggttg acctgcaaat aagtgccgac
     4321 acccgacgca accatcgcca tcgacacgag atacgccgtc atctccaccg gcagttccag
     4381 cgcgccgccc acaatcagcg cgggcgtaat catcggcacg aaaatcgcca aaagatgggt
     4441 aaccgcgctc aacagcgcat taccgaacgg cggcctatcc tccaaaccgt acaccaaatc
     4501 aggcgcatcc gccccttttc ccatatgacc gctcataatg tttccttgct tcaaatgttg
     4561 aaaaaaccaa agcgcggatt gtagcgaatc cgccataccg cttcaatttc gatttcggac
     4621 ggcatacgcg cccgtccggc aaacagattc cgaaccgtcg ccgccggaat atcgtttgca
     4681 aaacgcaata acctgatttc aaacacaaaa atacaaaccc gacgcatccg ccgccaagcc
     4741 gccccgtgca taccggaccc gccggatttc acacctgcgg taaagtaggc tacaatcgga
     4801 agcattaccg ccccctacac cacaactgat aaaaggttct gtatgttaca aggtagcctg
     4861 gttgccctga ttaccccgat gaatcaagac ggcagcatcc attacgaaca actccgcgac
     4921 ttaatcgact ggcacattga aaacggcacg gacggcatcg tcgccgtcgg cacgacaggc
     4981 gaatccgcca ccctctccgt cgaagaacac accgccgtta tcgaagccgt cgtcaaacac
     5041 gttgccaaac gcgtccccgt catcgccggc acaggggcga acaacaccgt cgaagccatc
     5101 gccctttccc aagccgccga aaaagccggc gcggactaca ccctctccgt cgtcccctat
     5161 tacaacaaac cttcgcaaga aggcatgtac cgccatttca aagccgttgc cgaagccgcc
     5221 gcgattccga tgatactcta caacgttccc ggccgtaccg tcgtcagcat gactaacgac
     5281 accatcctgc gcctttcaga aatccccaat atcgtgggcg ttaaagaagc cagcggcaac
     5341 gtcggcagca acatcgaact catcaaccgc gcccccgaag gcttcgtcgt cctgtccggc
     5401 gacgaccaca ccgccctacc gttcatgctg tgcggcggac acggcgtgat taccgtagcc
     5461 gccaacgccg cacccaagct ctttgccgat atgtgccgcg ccgcgctgca aggcgacatt
     5521 gccctcgcac gcaagctcaa tgaccggctg attccgattt acgacaccat gttctgcgaa
     5581 cccagccccg ccgcaccgaa atgggcggta tccgccctgg gcagatgcga accgcacgtc
     5641 cgcctgccgc tcgttccgct gacggaaggc ggacaggcaa aagtccgcgc cgccctgaaa
     5701 gcctcaggac aactctaaat ataactatgc cgtctgaacc gttcggacgg cataacgcaa
     5761 caaacacttt aatatccatc acacaggatg acacgatgac ccatatcaaa cccgtcattg
     5821 ccgcgctcgc actcatcggg cttgccgcct gctccggcag caaaaccgaa cagcccaagc
     5881 tcgactacca aagccggtcg caccgcctga tcaaactcga agtcccacct gatttgaaca
     5941 accccgacca aggcaacctc taccgcctgc ctgccggttc gggcgccgtc cgcgccagcg
     6001 atttggaaaa acgccgcaca cccgccgtcc aacagcctgc cgatgccgaa gtattgaaaa
     6061 gcgtcaaagg tgtccgcctc gagcgcgacg gcagccaacg ctggctcgtt gtcgacggca
     6121 agtctcatgc cgaaatctgg ccgctcctga aagccttttg gcaggaaaac ggcttcgaca
     6181 tcaaatccga agaacccgcc atcggacaaa tggaaaccga gtgggcggaa aaccgtgcca
     6241 aaatccccca agacagcttg cgccgcctat tcgacacagt cggtttgggc ggcatctact
     6301 ccaccggcga gcgcgacaaa ttcatcgtcc gtatcgaaca gggcaaaaac ggcgtttccg
     6361 acatcttctt cgcccacaaa gccatgaaag aagtgtacgg cggcaaagac aaagacacga
     6421 ccgtatggca gccctccccg tccgatccca acctcgaagc cgctttcctg acgcgcttta
     6481 tgcaatattt gggcgttgac ggacagcagg cggaaaacgc atcggcaaaa aacccgaccc
     6541 tgcccgccgc caacgaaatg gcgcgtatcg aaggcaaaag cctgattgtc tttggcgact
     6601 acggcagaaa ctggcggcgc accgcgctcg ccctcgaccg catcgggctg accgtcgtcg
     6661 gtcaaaacac cgaacgccac gctttcctgg ttcaaaaagc cccgaacgaa agcaatgcag
     6721 ttaccgaaca aaaacccggc ctgttcaaac gcctgctggg caaaggcaaa gcggagaaac
     6781 ctgccgaaca gccggaactg attgtctatg ccgagcctgt cgccaacgtc tcgcgcatcg
     6841 tcctgctcaa caaagacggc agcgcatatg ccggcaaaga cgcatccgca ttattgggca
     6901 aactccattc cgaactgcgt taaaccgttc aaaacaaaag cagcttccaa acagaagctg
     6961 cttttttgtg cggaactttt tacaacaacc gaggaaaaat atcctcaacc gcctgaacca
     7021 acgcatccgc caaaggcgga tcgaacgcac gatgccctgc ctgaaccacc ctcaattccg
     7081 cttccggaaa ggctttcgac agcgcccacg cactctgcat cggcgtacac aaatcatacc
     7141 gcccctgcac gataatggtc gggatatgct gtattttgcc gatattgttc aaaatcgccc
     7201 tatcgccctg caaccagccg ccgttgacaa aataatggtt ttccaaacgc gcgattgcca
     7261 gcgaggcata agcatcttca tccacttcct ccggctcgaa acggatcaga tagctttccc
     7321 aatccgccca agcctttgcg gcagacaggc acacttcttc atcttgatga aacagcaacc
     7381 cgtgatacgc ctcaatcagc cggttccgcc gattttcagc aatcggcgcg acaaattttt
     7441 gccattgttc cggataaatc cggctcacac cgcccgcctc gttcagccac gccgtttcag
     7501 acggcctgca caaaaatatc ccgcgcaaca ccaatccctt tacccgttcc ggatgggttt
     7561 gggcataagc cagcgacaaa gtactgcccc acgaaccgcc gaacaccagc catttcccga
     7621 tacccagcat ttcacggact ttttcaatat ccgccaccaa atcccaagtc gtattgtctt
     7681 ccgcacaagc atacgggcgc gaacgtccgc aaccgcgctg gtcgatgatg acgatgcgga
     7741 acacatcggg attgaaaaaa ccccgacatt caggcgaagc ccccgcgccc ggcccgccat
     7801 gtaaaaaaat aaccggcaca ccgtcgggat tgcccgattc ctcccaataa atttgatgaa
     7861 tttcagacac ctgcaagtat ccgctatgaa aaggctgttt tatctcatac atcatcttct
     7921 cccatattgc ttctgacaat ccgaacattc ccacacgcaa catcacgcac gagacacaag
     7981 ccgccccgaa aggcaaatgc cgaaaaatcg cgatatagtg aattaacaaa aatcaggaca
     8041 aggcgacgaa gctgcagaca gtaca
//
LOCUS       DAXIDM010000088         7969 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000088 DAXIDM010000000
VERSION     DAXIDM010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7969
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.088"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(144..1067)
                     /gene="era"
                     /locus_tag="ACFOAE_001603"
     CDS             complement(144..1067)
                     /gene="era"
                     /locus_tag="ACFOAE_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004286080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFC6885062.1"
                     /translation="MDIETFLAGERAADGYRCGFVAIVGRPNVGKSTLMNHLIGQKIS
                     ITSKKAQTTRNRVTGIYTDDTAQFVFVDTPGFQTDHRNALNDRLNQNVTEALGGVDVV
                     VFVVEAMRFTDADRVVLKQLPKHTPVILVVNKIDKDKAKDRYALEAFVAQVRAEFEFA
                     AAEAVSAKHGLRIANLLELIKPYLPESVPMYPEDMVTDKSARFLAMEIVREKLFRYLG
                     EELPYAMNVEVEQFEEEDGLNRIYIAVLVDKESQKAILIGKGGERLKKISTEARLDME
                     KLFDTKVFLKVWVKVKSGWADDIRFLRELGL"
     gene            complement(1114..1833)
                     /gene="rnc"
                     /locus_tag="ACFOAE_001604"
     CDS             complement(1114..1833)
                     /gene="rnc"
                     /locus_tag="ACFOAE_001604"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFC6885063.1"
                     /translation="MKDDVLKQQAHAAIQKKLGYAFRDISLLRQALTHRSHHAKHNER
                     FEFVGDSILNYTVARMLFDAFPKLTEGELSRLRASLVNEGVLAEMAAEMNVGDGLYLG
                     AGELKSGGFRRPSILADAMEAMFAAVSFDADFNTAEKVVRHLFADRVRRADFQNQAKD
                     GKTALQEALQARRFALPKYRIEEQIGYANDSMFVISCDLGELGFVCRAKGTSRKAAEQ
                     EAAKEALKWLEEKLPLKKKKK"
     gene            2000..2323
                     /locus_tag="ACFOAE_001605"
     CDS             2000..2323
                     /locus_tag="ACFOAE_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HFC6885064.1"
                     /translation="MNAFAQALSSALDRCIATNTVAKQNRPVGFLYREAPVFENDSGW
                     RFFSGDETDEYTDDPDNFSIVSLADIAKTNPETAVLLSQPEGSAWELAEDGTFQTVAD
                     WQPQD"
     gene            2370..2846
                     /gene="ribH"
                     /locus_tag="ACFOAE_001606"
     CDS             2370..2846
                     /gene="ribH"
                     /locus_tag="ACFOAE_001606"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HFC6885065.1"
                     /translation="MNTIAPNLDGKHLRIGIVQARFTNEIGSEMLKVCCRTLQELGVA
                     DENITVATVPGALEIPIALMNLASSEKFDALIAIGVVIRGETYHFELVSNESGAGVSR
                     VALDYNIPIANAVLTTENDAQAIERIEEKASDAAKVAVECANLVNLLLEEQFEDEE"
     gene            2924..3349
                     /gene="nusB"
                     /locus_tag="ACFOAE_001607"
     CDS             2924..3349
                     /gene="nusB"
                     /locus_tag="ACFOAE_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFC6885066.1"
                     /translation="MKTARRRSRELAVQAVYQSLINRTAAPEIAKNIREMSDFAKADE
                     ELFNKLFFGTQTNAAEYIQQIRPLLDRDEKDLNPIERAVLLTACHELSAMPETPYPVI
                     INEAIEVTKTFGGTDGHKFVNGILDKLAAQIRPDEPKRR"
     gene            complement(3716..4750)
                     /gene="pyrC"
                     /locus_tag="ACFOAE_001608"
     CDS             complement(3716..4750)
                     /gene="pyrC"
                     /locus_tag="ACFOAE_001608"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_process: GO:0019856 - pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFC6885067.1"
                     /translation="MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKP
                     PVVSVADALAYKARIMAVLPEGSAFEPLMTLYLTDQATPELVREAKAAGIVAFKLYPA
                     GATTNSDSGVTDLFKLIPVLEEMAKQDILFLVHGEVTDPEIDIFDREAAFIERVMKPV
                     LAQVPNLKVVFEHITTAEAARLVLEAGDNVAASVTPQHLLLNRNDLLVGGVRPHHFCL
                     PVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYA
                     EVFEKAGALDKLEAFASKNGARFYGIPENAGTITLVKQSQTVPASVPYGDGELVPMRA
                     GGEIGWTVQY"
     gene            complement(4966..5112)
                     /locus_tag="ACFOAE_001609"
     CDS             complement(4966..5112)
                     /locus_tag="ACFOAE_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010791287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885068.1"
                     /translation="MPSEMRMSRPTALFLNIVCAACRFKNKPSGVQCRHFGRIAADLF
                     RNGC"
     gene            complement(5113..5337)
                     /locus_tag="ACFOAE_001610"
     CDS             complement(5113..5337)
                     /locus_tag="ACFOAE_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HFC6885069.1"
                     /translation="MNSETLDVTGLKCPLPILRAKKALAQMQQGDVLTVLATDGGAPG
                     DFEAFCRQTGHVLLDASEQDGVFTLVVKHK"
     gene            5446..6046
                     /locus_tag="ACFOAE_001611"
                     /pseudo
     CDS             5446..6046
                     /locus_tag="ACFOAE_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CNP1-like family protein"
     gene            complement(6106..6978)
                     /gene="accD"
                     /locus_tag="ACFOAE_001612"
     CDS             complement(6106..6978)
                     /gene="accD"
                     /locus_tag="ACFOAE_001612"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFC6885070.1"
                     /translation="MSWLDKILPPKIKNRSKDGSSNVPEGLWHKCPSCSATVYSTELQ
                     QNNQVCPKCNHHNPLSARQRLNLLLDEDGREEVAGNVKPTDPLKFKDGKKYPDRLSAA
                     RKLTGEDDALVVMKGKMNGLPVVVAAFEFRFIGGSMGSVVGERFVQGIRRAVADNCPF
                     VCVAASGGARMQEGVNSLMQMTKTSAALHLLTEKRLPFISVLTDPTMGGVSASFAFLG
                     DVVLAEPNALIGFAGPRVIEQTVRETLPEGFQRAEFLLEKGAIDQIVDRRDMKRRISD
                     LITLLCRQDKVSAA"
     gene            complement(7015..7800)
                     /gene="trpA"
                     /locus_tag="ACFOAE_001613"
     CDS             complement(7015..7800)
                     /gene="trpA"
                     /locus_tag="ACFOAE_001613"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HFC6885071.1"
                     /translation="MSRIRQAFAALDGGKALIPYITVGDPDIRTTLALMHGMVANGAD
                     ILELGVPFSDPMADGPVIQRAAERALANGISLRDVLDVVRKFRETDTQTPVVLMGYLN
                     PVHKMGYREFAQEAAKAGVDGVLTVDSPVETIDPLYRELKDNGVDCIFLIAPTTTEDR
                     IKTIAELAGGFVYYVSLKGVTGAASLDTDEVSRKIEYLHQYIDIPIGVGFGISNAESA
                     RKIGRVADAVIVGSRIVKEIENNAGNEAAAVGALVKELKDAVR"
BASE COUNT         1916 a         2402 c         1899 g         1752 t
ORIGIN      
        1 atgcacagat aatatcaacc cgtttttaac aaaaatattc ccgattgaaa caaaatgccg
       61 tctgaaacac gttcagacgg catttttgca tcgatcccga caggatttga agctatcggg
      121 gaatcggatt gtcctttgag ggtttacaaa cccagctcgc gcaggaagcg gatgtcgtcc
      181 gcccaaccgg atttgacttt aacccacact ttcaaaaata ctttggtatc aaacagtttt
      241 tccatatcca accgcgcttc ggtggagatt ttcttcaaac gctccccgcc tttgccgatt
      301 aaaatcgcct tttggctttc cttatcgacc aaaacggcga tatagatgcg gttcaaaccg
      361 tcttcctctt caaactgctc cacttcgacg ttcatcgcat aaggcaattc ctcgcccaaa
      421 tagcggaaca atttttcacg cacgatttcc atcgccaaaa aacgcgccga tttgtccgta
      481 accatgtctt cgggatacat cggcacgctt tcgggcagat acggcttaat cagctccaac
      541 aggttggcaa tccgcaatcc gtgtttcgcg ctgaccgcct ccgccgccgc aaattcaaat
      601 tcggcgcgca cctgggcaac aaacgcctcc agcgcgtaac ggtctttcgc cttgtcctta
      661 tcgattttgt tgaccactaa aatgaccggc gtgtgcttgg gcagttgttt caacacgacg
      721 cggtcggcat cggtaaaacg catcgcttcc acgacgaaaa ccaccacatc cacgccgccg
      781 agcgcctcgg taacattttg attcagcctg tcgttgagcg cgttgcggtg gtcggtttga
      841 aagccgggcg tatcgacaaa cacgaactgc gcggtatcgt cggtataaat ccccgttacg
      901 cggttgcgcg tcgtctgcgc ctttttgctg gtaatactga ttttctgacc gatgagatgg
      961 ttcatcagcg ttgatttgcc cacgttcgga cggccgacaa tcgctacgaa gccgcaacgg
     1021 tatccgtcgg cggcgcgttc ccctgcaagg aaggtttcaa tatccatatt cgctttcata
     1081 tccatatttc agacggcata ttcacacacc gcctcatttc tttttcttct tcagcggcag
     1141 tttctcttcc agccatttca aagcctcttt cgccgcctcc tgttccgccg ccttgcggct
     1201 cgtccctttg gcacggcaca cgaaacccag ttcgcccaaa tcgcaggaaa tgacaaacat
     1261 actgtcgttg gcataaccga tttgctcttc gatacggtat ttcggcaagg cgaaacggcg
     1321 cgcctgcaac gcctcctgca aagcagtttt gccgtctttt gcctgatttt gaaaatcggc
     1381 gcgccggacg cgatcggcaa acaaatggcg caccaccttt tccgccgtgt tgaaatcggc
     1441 atcgaagctg acggcagcaa acatcgcctc catcgcgtct gccagtatcg aaggccgtct
     1501 gaagccgccg ctcttcaact cgcccgcccc caagtacagg ccgtcgccga cattcatttc
     1561 cgccgccatt tccgccagca cgccctcatt gaccagactt gcccgcaacc gcgacaactc
     1621 gccctcggtc aacttcggaa acgcgtcaaa cagcatccgc gccaccgtat aattcaaaat
     1681 cgaatcaccg acaaactcga accgctcgtt gtgcttcgca tgatggctcc tgtgcgtcaa
     1741 agcctgccgc aaaagcgaaa tatcgcggaa cgcgtagccc agtttcttct gtatcgccgc
     1801 gtgtgcctgc tgtttcaaaa catcgtcttt cattaccgtc ttccgcaaaa aacagcccga
     1861 atgcgtttcc atactccaaa aatacagaaa caccttaagg ctgcaaacgg cgcacattgt
     1921 accaccaaac cgccgccgtc tgccgacaac gcacgaatcg tggtaaaatc cgtaagtttt
     1981 cccccaacgt attcccgtaa tgaacgcatt tgcacaagca ctttcctcgg cactcgaccg
     2041 ctgtatcgcc accaacaccg tcgccaaaca aaaccggccc gtcggcttcc tctaccgcga
     2101 agcccccgtt tttgaaaacg acagcggctg gcgtttcttc agcggcgacg agaccgacga
     2161 atacaccgac gatcccgaca acttcagcat cgtcagcctc gccgacatcg ccaaaaccaa
     2221 ccctgaaacc gccgtactgc tttcccaacc tgaaggcagc gcgtgggaat tggcagaaga
     2281 cggcacattc caaaccgtcg ccgactggca accgcaagac tgaaaccttc agacggcatt
     2341 ccgaaacccc gaataccaaa ggacacccaa tgaacaccat cgcccccaac cttgacggca
     2401 aacacctccg catcggcatc gtacaggcac gtttcaccaa cgaaatcggc agcgaaatgc
     2461 tcaaagtctg ctgccgcacc ctccaagaat tgggcgtggc agacgaaaac attaccgtcg
     2521 ccaccgtacc cggcgcgctt gaaatcccca tcgcgctgat gaaccttgcc tcttccgaaa
     2581 agtttgacgc actgattgcc atcggcgtcg tcatccgtgg cgaaacctac catttcgagc
     2641 tggtttccaa cgaatccgga gcaggggtca gccgcgtcgc actcgactac aacattccga
     2701 ttgccaatgc cgtcctgacc accgaaaacg acgcgcaggc aatcgaacgg attgaagaaa
     2761 aagcctcgga tgccgccaaa gtcgccgtag aatgcgccaa cctcgtcaac ctgctgctcg
     2821 aagaacagtt tgaagacgaa gaataacaaa cagggcgtac accgatacgc cctttccgtt
     2881 tcagacggca taccgtgccg cccaaccgtt tcaaggaaaa atcatgaaaa cagcccgccg
     2941 ccgttcccgc gagcttgccg tacaagccgt ttaccaatcc cttatcaacc gcaccgccgc
     3001 gcccgagatt gctaaaaaca tccgcgaaat gtccgacttt gccaaggcag acgaagaatt
     3061 gttcaacaaa cttttcttcg gcacgcaaac caatgcggca gagtacatcc aacaaatccg
     3121 cccgctgctc gacagggacg aaaaagacct caaccccatc gaacgcgccg tcctgctgac
     3181 cgcctgccac gagctgtccg ccatgcccga aacgccctac cccgtcatca tcaacgaagc
     3241 catcgaagtt accaaaacct tcggcggcac ggacgggcac aaattcgtca acggcatcct
     3301 cgacaaactc gctgcccaaa tccgccccga cgagcccaaa cgccgttgat gcatcacaaa
     3361 tttaaagaaa gttctatgtc cttatttctg ctttctttgt ttcgtcattc ccacgcatgt
     3421 gggaatttgg ttttttgaat tttgggtatt tcaaataaat tctgaaactt caatctcgtc
     3481 attcccgcgc aggcgggaat ccggtttttt gagttgctgc cgtttttgat aaactctggt
     3541 cgcatcgaat ttccggattc ctgccttcgt gggaatggcg aaatttgaaa attgtgggaa
     3601 tttatcggaa ataaccgaaa cgtaacaaac tcaaacgccg ttgacgtatc aatcagtcaa
     3661 caacacaaat gccgtctgaa aaacctttca gacggcattt tgcttgaccg ttcaatcaat
     3721 actgtaccgt ccagccgatt tcgccgcccg cgcgcatcgg gacaagttcg ccgtcgccgt
     3781 agggaacact tgcggggacg gtttggcttt gtttgacgag ggtgatcgtg ccggcgtttt
     3841 ccggaatgcc gtaaaacctt gcgccgtttt tcgaggcaaa ggcttcgagt ttgtccaacg
     3901 cgcctgcttt ttcaaacact tcggcgtaaa gctcgatggc ggtcatcgcg ctgaacatac
     3961 cggcgcaacc gcaggcgttt tctttagcgg atttggcgtg cggcgcggaa tctgtgccga
     4021 ggaagaattt gtgcgccttc tcgccggtaa cggcggcaac caatgcctga cggtgggttt
     4081 cgcgcttgag gacgggcagg cagaaatgat gggggcgcac gccgccgacc aagaggtcgt
     4141 tgcggttgag caggaggtgt tgcggggtca cagaggcggc aacgttgtcg cctgcttcca
     4201 aaaccaggcg ggcggcttcg gcggtggtaa tgtgttcaaa cacgacttta agattcggca
     4261 cttgcgccaa aacgggtttc atcacgcgct cgataaaggc ggcttcgcgg tcgaaaatgt
     4321 cgatttcggg gtcggttact tcgccgtgaa cgaggaacag gatgtcctgt tttgccattt
     4381 cttccaacac ggggatgagc ttgaataggt cggttacgcc ggaatcggaa ttggtcgtcg
     4441 cgccggcggg gtagagtttg aaggcgacga tgccggcggc tttggcttcg cgcaccagct
     4501 cgggcgtggc ttggtcggtc aggtaaagcg tcatcagcgg ctcaaacgcg ctgccttcgg
     4561 gcaacaccgc cataatgcgc gctttgtagg caagcgcgtc ggctacactg acgacgggcg
     4621 gtttgaggtt gggcataatg acggcgcgcc ccatttggcg ggcggtataa ggggcaacgg
     4681 ctttgagcgc gtcgccgtcg cgcaggtgca ggtgcatatc gtcggggcgg ataatggtca
     4741 gggtttgcat ggttgttcct ttttaggttt tggctgcgtt tgaatacccg gtcgattcca
     4801 tccgtttgcc gggggaaagc cggttattcc gtccggtcgg aaaccggttc cattggatga
     4861 aaggcatttt gtccgactga ttgggttgca tcaacggaat cttcaaacac agcctttaga
     4921 ttttgattgt gcttgggttt tgcttctttg ccgacggcaa ggcggttaac agccattccg
     4981 gaacaaatcg gcggcgatac gcccgaaatg ccgacactgc acgccggacg gtttgttttt
     5041 gaaacggcac gcggcacata cgatattcaa aaacaacgcc gtcgggcggg acatccgcat
     5101 ttcagacggc atttatttgt gcttgacgac cagcgtgaac acgccgtcct gttcggaagc
     5161 atccaacagc acatgaccgg tttggcggca aaaagcctca aaatcccccg gtgcgccgcc
     5221 gtcggttgcc agaacggtca acacgtcgcc ctgctgcatt tgcgccaaag cctttttcgc
     5281 ccgcaaaatc ggcaggggac atttcaatcc ggttacgtct aaagtttcgc tgttcatcgt
     5341 ttgtaccgtt taaaaaatgg gaatcggggg gagattatac cccagttgct tgcagccccc
     5401 tttgccaacc cataaaataa cgccgttttc aatttggaga aacttatgcg ccgcaccgcc
     5461 ctcctgctgc tcgcactcac cgccggcacg tcccttgctg ccggcttcaa ccaaaaagac
     5521 acgccgatca acacccgcta ccgcgaaacg cccgaagaag ccgccgcccg cgaatttaaa
     5581 gaacataccg ccaaactgcc gccgctgccc gatacgcact cggacggctg gtttgacatt
     5641 tatgtggatg aaaattacgg caaacagccg aaaatcctgc tcgacagcct gcaaattatg
     5701 cccgcgcccg acggcagcat ccgctacatt ctcaatatcc gctccgacaa aggctacgac
     5761 aacctgactg ccgaaggcat attctgcgcc cgcttctcca tcaggttcgg caacggcaaa
     5821 ccttcctcct ataaagtgtt cggctacggc gacacggtca accgccgctg gatacagccc
     5881 cgaaacgccg aatggaaacc gataggcggt acattaagcc gcaacgacgc actgcgcacc
     5941 gtcctgtatc aggcattctg cgagggcggt gtacccgccg acacgaaaac gcctgaaaga
     6001 acgtgccgga cgctatgccc cgtcgataaa gccgcacaac aaataaccag acacaaaaat
     6061 accgtctgaa acatcggttt cagacggtat tcgattcatc agccatcaag cggcggaaac
     6121 tttgtcctga cggcacaaca gcgtaatcaa atcactgatg cgccgcttca tatcgcggcg
     6181 gtcgacaatc tggtcgattg cgcctttttc cagcaaaaac tcggcacgct ggaagccttc
     6241 cggcagcgtt tcgcgcaccg tctgctcaat cacgcgcgga ccggcaaagc cgattaatgc
     6301 attgggttcg gcaagcacga catcgcccaa aaatgcgaag ctggcggata cgccgcccat
     6361 agtcggatcg gtcaataccg atataaacgg caggcgtttt tccgtcagca aatgcagcgc
     6421 ggcactggtt ttcgtcatct gcatcaacga gttcacaccc tcctgcatac gcgcaccgcc
     6481 ggaagccgcc acacagacga acggacaatt gtcggcaacc gcccgacgga taccttgtac
     6541 gaatcgttcg cccacaaccg aacccatcga accgccgata aagcggaact caaacgcagc
     6601 aaccacaacg ggcagaccgt tcatcttgcc tttcattacc accaaagcat catcttcccc
     6661 ggtcagcttg cgtgccgcac tcaaacgatc cggatatttt ttgccgtctt taaacttcaa
     6721 aggatctgtc ggtttgacat ttccggcaac ctcctctctg ccatcctcat ccaaaagcag
     6781 attcaggcgt tgtcgtgccg acaacggatt gtggtggttg catttcggac aaacctgatt
     6841 gttctgctgc aactcggtcg aataaacggt tgccgaacaa gacggacatt tgtgccacaa
     6901 accctcggga acattggaag aaccgtcttt gctgcggttt ttgattttgg gtggcaggat
     6961 tttatctaac cagctcatgg acaactccta aaatatttag aatgcgtgac agaatcagcg
     7021 cacggcatcc ttcaactctt tgaccaaagc accgacggcc gcagcctcgt tgcccgcatt
     7081 gttttcaatc tctttcacaa tccggctgcc gacaatgacc gcgtcggcaa cccggccgat
     7141 tttgcgcgcg ctttccgcat tgctgatgcc gaaaccgaca ccgatgggaa tatcgatata
     7201 ctgatgcaaa tactctattt tacgcgaaac ctcatccgta tccaaacttg ccgcgcccgt
     7261 tacgcccttg agcgaaacat aatagacaaa tccgcctgcc agctcggcaa tggttttaat
     7321 acggtcttcc gtcgtcgtcg gcgcaatcag gaaaatacag tcgaccccgt tatccttcag
     7381 ctcgcgatag agcggatcga tggtttcgac aggggaatcc accgtcaaca cgccgtccac
     7441 acccgccttt gcggcttcct gagcaaactc ccgataaccc atcttatgta cagggttcaa
     7501 atatcccatc aaaacaaccg gcgtttgcgt gtcggtttca cggaattttc tgacgacatc
     7561 caagacatcg cgcagcgaaa tcccgtttgc caacgcccgc tccgccgcac gctgaataac
     7621 cggcccatcc gccatcggat cggaaaacgg cacgcccaac tccaaaatat ccgcaccgtt
     7681 tgcaaccatg ccgtgcatca atgccaaagt tgtccgaata tcggggtcgc ccaccgtaat
     7741 atagggaatc aatgcctttc cgccatccaa agcggcaaaa gcctgccgga ttctgctcat
     7801 ttgtctcttc catcctatcg gcaaatatgc cataaaacac aatcagtaaa tttttcccag
     7861 tataacattt gcggtacgga taggcgaata cggcaaacag aaaccacgca aatcagagcc
     7921 gccgtttgaa cgaggcggaa ataaacggca agcatctcgg attatagtg
//
LOCUS       DAXIDM010000089         7967 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000089 DAXIDM010000000
VERSION     DAXIDM010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7967
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.089"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(218..289)
                     /locus_tag="ACFOAE_001614"
     tRNA            complement(218..289)
                     /locus_tag="ACFOAE_001614"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(254..256),aa:Arg,seq:cct)
     gene            complement(309..755)
                     /locus_tag="ACFOAE_001615"
     CDS             complement(309..755)
                     /locus_tag="ACFOAE_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFC6885072.1"
                     /translation="MNFSFVPLFLVTLILLGVVSNNNSITISATILLLMQQTALVQFV
                     PLVEKHGLNLGIILLTIGVLSPLVSGKAQVPPVAEFLNFKMISAVFIGIFVAWLAGRG
                     VPLMGQQPVLITGLLIGTVIGVAFMGGIPVGPLIAAGILSFVVGKG"
     gene            complement(760..1734)
                     /gene="ispB"
                     /locus_tag="ACFOAE_001616"
     CDS             complement(760..1734)
                     /gene="ispB"
                     /locus_tag="ACFOAE_001616"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HFC6885073.1"
                     /translation="MLENLPYFQRHLPEDLAKVNEVINRAVQSDVALISQIGTYIISA
                     GGKRLRPIMTILAGKAVGYDDEKLYALAAMVEFIHTSTLLHDDVVDESDLRRGRATAN
                     NLFGNAAAVLVGDFLYTRAFQLMVASGSMRVLEVMADATNIIAEGEVMQLMNIGNTDI
                     TEEQYVRVIQYKTAKLFEAAAQVGAILGKASPEHEQALKDYGMYVGTAFQIIDDVLDY
                     SGETEETGKNVGDDLAEGKPTLPLIYLMRQGSEQVANDVRTALENADRSYFEKIHDYV
                     VRSDALAYSIGEARKAVDCAVAALDALPDSEVKDAMIQLAKESLVRVS"
     gene            1958..2266
                     /gene="rplU"
                     /locus_tag="ACFOAE_001617"
     CDS             1958..2266
                     /gene="rplU"
                     /locus_tag="ACFOAE_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFC6885074.1"
                     /translation="MYAVVKTGGKQYKVSVGEKLKVEQIPAELDSQIELTEVLMIADG
                     ESVKVGAPFIEGAKVTAKVVAHGRGEKVRIFKMRRRKHYQKRQGHRQNFTQIEIVAIA
                     "
     gene            2291..2563
                     /gene="rpmA"
                     /locus_tag="ACFOAE_001618"
     CDS             2291..2563
                     /gene="rpmA"
                     /locus_tag="ACFOAE_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFC6885075.1"
                     /translation="MASKKAGGSTRNGRDSEAKRLGVKAYGNELIPAGSIIVRQRGTK
                     FHAGDNVGMGKDHTLFAKVDGYVEFKTKGALNRKTVSIRPYTGSEE"
     gene            2952..4136
                     /gene="ubiM"
                     /locus_tag="ACFOAE_001619"
     CDS             2952..4136
                     /gene="ubiM"
                     /locus_tag="ACFOAE_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016709 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen, NAD(P)H as one donor, and incorporation
                     of one atom of oxygen [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-demethoxyubiquinol-8 5-hydroxylase UbiM"
                     /protein_id="HFC6885076.1"
                     /translation="MSLHSDILVVGAGPAGLSFAAELAGSGLKVTLIERSPLTVLQNP
                     PYDGREIALTHFSREIMQRLGMWDKIPENEIYPLRDAKVLNGRSDYQLHFPQPTEARG
                     EPADCLGYLISNHNIRRAAYEVVSQLDNITILTDTAVKEVKTSDNEAQVILENGKILT
                     ARLLLAADSRFSQTRRQLGISSDMHDYSRTMFVCRMKHTLSNQHTAYECFHYGRTIAL
                     LPLEEHLTNTVITVDTDKINSVQNLSPEELAASVKEQLKGRLGDMELVSSIHHYPLVG
                     MIAKRFYGKRSALIGDAAVGMHPVTAHGFNLGLSSADILAKLILEAEQRGQDIGAASL
                     LEKYSSKHMLHAQPLYHGTNMMLKLFTNETAPAKLLRGLVLRAGNNFPPLKKLITKQL
                     TG"
     gene            complement(4407..4562)
                     /gene="rpmG"
                     /locus_tag="ACFOAE_001620"
     CDS             complement(4407..4562)
                     /gene="rpmG"
                     /locus_tag="ACFOAE_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009766925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFC6885077.1"
                     /translation="MRDKIKLESSAGTGHFYTTTKNKRTMPGKLEIKKFDPVARKHVV
                     YKETKLK"
     gene            complement(4594..4827)
                     /gene="rpmB"
                     /locus_tag="ACFOAE_001621"
     CDS             complement(4594..4827)
                     /gene="rpmB"
                     /locus_tag="ACFOAE_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007586227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFC6885078.1"
                     /translation="MARVCKVTGKRPMSGNNVSHANNKTKRRFLPNLQSRRFWVESEN
                     RWVRLRVSNAALRTIDKVGIDVVLADLRARGEA"
     gene            complement(5077..6603)
                     /gene="farB"
                     /locus_tag="ACFOAE_001622"
     CDS             complement(5077..6603)
                     /gene="farB"
                     /locus_tag="ACFOAE_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid resistance MFS efflux transporter
                     permease subunit FarB"
                     /protein_id="HFC6885079.1"
                     /translation="MDYPPLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLG
                     AATTQGTWVITSFAVANAVSVPLTGFLAKRIGEVKLFTAAAVGFVITSWLCGIAPNLQ
                     ALVIFRILQGFIAGPLIPLSQSLLMASYPPAKRTLALALWAMTVVVAPVLGPILGGWI
                     SGNWHWGWIFFINIPIGIISAWITWKHLKYRETETVKMPTDYVGLTLMVVGIGALQMM
                     LDRGKELDWFASGEIITLGVVALVCLSYFIVWELGEKYPIVDLSLFKDRNFTVGVIAT
                     SLGFMVYMGTLTLLPLVLQTNLGYTSTWAGLAAAPVGILPVFLSPLIGRFGNKIDMRL
                     LVTASFLTFAFTFYWRTDFYADMDIGNVIWPQFWQGAGVAMFFLPLTTITLSHMKGGQ
                     IAAAGSLSNFLRVLMGGVGVSVVSTLWERREALHHTRFAEHITPYSATLHETAAHLSQ
                     QGISDIQTLGIINNTITQQGFIIGSNEIFMAGSLLFIIMIPVIWLAKPPFHSSGGGGH
                     "
     gene            complement(6627..7781)
                     /gene="farA"
                     /locus_tag="ACFOAE_001623"
     CDS             complement(6627..7781)
                     /gene="farA"
                     /locus_tag="ACFOAE_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid resistance MFS efflux transporter
                     adaptor subunit FarA"
                     /protein_id="HFC6885080.1"
                     /translation="MDTHTDETKLQNTQAKRKRRLTALTLLFALAAAAAGSAFFLWWQ
                     HEEETEDAYVAGRVVQVTPQKGGTVRKVLHDDTDAVKKGDVLAVLDDDNDVLAYERAK
                     NELIQAVRQNRQQNAATSQAGAQVALRRADLARAQDDLRRRSALAESGAVSAEELAHA
                     RAAVSQAQAAVKAALAEESSARAALGGQVSLREQPAVQTAIGRLKDAWLNLQRTQIRA
                     PADGQVAKRSVQVGQQVAAGAPLMAVVPLSDVWVDANFKETQLRHMKIGQPAELVSDL
                     YGKQIVYRGRVAGFSAGTGSAFSLIPAQNATGNWIKVVQRVPVRIVLNREDVDRHPLR
                     IGLSMTVKVDTSAAGAPVSKTPGAALPEMESTDWSEVDRTVDEILGQSAP"
BASE COUNT         2146 a         2194 c         1849 g         1778 t
ORIGIN      
        1 tttaaattta atccactata tcataaaaca acagatttcc aagccggaac atcttttacg
       61 gagcctgaaa atcatttcat gattctaccg tcctaaaggt cggtttttca agcaggaaga
      121 aaaagttttc agatggcaaa aaagccctcc aacactgaaa ggccttatat cggaaacttc
      181 ccgcaacacg ggaaacagac aaatgcaaat cgtcaaacct cgccaacagg aatcgaacct
      241 gtattttacg cttaggaggc atacgttcta tccgttgaac tatggcgagc cgaaatgaaa
      301 aggagatttt aaccctttcc gacgacaaaa gacaagatgc cggccgcaat cagcggcccg
      361 acagggatac cgcccataaa tgccaccccg ataaccgtcc cgattaacag ccctgtaatt
      421 aaaacaggct gctgtcccat caaaggcacg ccgcgtcccg ccagccaagc cacgaaaata
      481 ccgataaaaa cggcggatat cattttaaaa ttcaaaaatt cggcaacggg aggaacctgc
      541 gcctttcctg aaaccaacgg actcaaaacc cctatggtca aaagaatgat accgagattc
      601 aacccgtgct tctcgaccaa cgggacaaac tgtaccaatg ccgtctgctg catcagcagc
      661 aatatggttg ccgagatggt aatcgaattg ttgttgctga ccacccccaa cagaatcagc
      721 gtaaccagaa acaggggaac aaaactgaaa ttcatcgcct caagacaccc tgaccaaaga
      781 ttccttcgcc agctgaatca tggcatcctt cacttcgctg tcgggcaggg catccaacgc
      841 ggcaacggca caatcgactg ctttgcgcgc ctcgcctatc gaatatgcca acgcatccga
      901 acggacgaca taatcgtgga ttttctcaaa atagctgcga tctgcatttt ccaaagcagt
      961 acgcacatcg ttcgcaacct gttcggaacc ctgacgcatc agataaatca aaggcaaagt
     1021 tggttttcct tctgccaaat cgtcgccgac gtttttacct gtttcttcgg tttcccccga
     1081 ataatccagc acatcatcaa taatttggaa tgccgtaccg acatacatac cgtagtcttt
     1141 caacgcctgt tcgtgttcgg gggaagcctt gcccaaaatt gcgccgacct gcgccgccgc
     1201 ttcaaataat tttgccgttt tatattggat cacccggaca tattgttctt cggtaatatc
     1261 cgtattgccg atgttcatca gctgcatgac ctcgccctcg gcaataatgt tggttgcatc
     1321 cgccatcact tccaaaacgc gcatactgcc cgaggcaacc atcagttgaa aggcgcgcgt
     1381 gtataaaaag tcgccaacca acactgccgc cgcattgccg aacagattgt ttgccgttgc
     1441 ccgtccacgg cgcaaatcgc tttcatcgac gacatcgtcg tgcaggaggg tggaagtgtg
     1501 gataaactcg accatcgccg ccagcgcata cagtttctcg tcatcataac cgaccgcctt
     1561 acccgccaaa atcgtcataa tcggacgcag gcgtttgccg cccgcgctga tgatatatgt
     1621 accgatttgc gaaatcagtg cgacatcgga ttgcaccgca cggttgatga cttcattgac
     1681 tttggcaagg tcttcaggca gatgtcgctg gaaatagggc agattttcga gcatggcaga
     1741 ctctcaggtt tacgtttccg tcaaacggca gataccgctt gaaagctgat tcaaatagcg
     1801 ggcaattata tcagcaaagc catcagggta catcttttca gacggcatat ggttatccga
     1861 accgcgcaaa ctttgacaaa acaggcaaat aacaataaaa tgccgagttc cgcacaatgg
     1921 tgtgcggata ttaaccataa cccttatgga gttgagtatg tacgcggtcg taaaaaccgg
     1981 cggcaaacag tataaagttt ccgtcggcga aaaattgaaa gtagaacaga taccagccga
     2041 actcgacagc caaatcgaac tgaccgaagt tttgatgatt gctgacggcg aatctgtaaa
     2101 agttggcgca ccctttatcg aaggtgcaaa agtaacggct aaagtagtgg cacacggtcg
     2161 tggcgaaaaa gtccgcatct tcaaaatgcg ccgccgcaaa cactaccaaa aacgccaagg
     2221 ccaccgccaa aatttcaccc aaatcgaaat cgtggcaatc gcctaacctt aaaacttagg
     2281 agcattacaa atggcaagta aaaaagcagg cggcagcacc cgcaacggtc gcgattcaga
     2341 agccaaacgc ttgggcgtta aagcctacgg caacgagctg attcccgcag gttccatcat
     2401 cgtacgccaa cgcggtacca aattccacgc aggcgacaac gtaggtatgg gcaaagacca
     2461 cactttgttc gccaaagttg acggttatgt cgaattcaaa accaaaggcg cgctgaaccg
     2521 taaaactgtc agcatccgtc cttacaccgg ttctgaagaa taatccaacc gatacctgaa
     2581 gccgcatctt ttcacgatgc ggctttttat agtggattaa caaaaatcag gacaaggcga
     2641 cgaagccgca gacagtacaa atagtacgga accgattcac ttggtgcttc agcaccttag
     2701 agaatcgttc tctttgagct aaggcgaggc aacgccgtac tggtttaaat ttaatccact
     2761 atacataccc cacacccgat ttgatacaca ttaagctgaa agtaaaaatc cgcatacacc
     2821 ctcccctgca tatttcttca acagtgggtt ttgatataat cgcctatctg ttacagatag
     2881 ttcaaacggc attcaaaccc ttacaaatac cgtctgaaat catcgacatc cgtctatgca
     2941 aaggatattt tatgagttta cacagcgaca tcctcgtcgt cggcgcaggc ccggcgggtt
     3001 taagttttgc agccgaactt gccggcagcg gtttgaaagt taccctgatc gaacgcagcc
     3061 cactgactgt tctgcaaaat cctccatatg acggacgcga aatcgccctg acccattttt
     3121 cccgcgaaat catgcagcgt ttgggtatgt gggacaaaat tcccgaaaac gaaatctacc
     3181 ctttgcgcga tgccaaagtg ctgaacggac gttccgacta ccagctccac tttccccaac
     3241 cgaccgaggc gcgcggcgag cctgccgact gtttgggcta tctgatttcc aaccacaata
     3301 tccgccgcgc tgcctacgaa gtcgtatccc aactcgacaa cattaccatt ctgaccgata
     3361 cggccgttaa agaagtcaaa acatctgaca acgaagcaca agtcatttta gaaaacggca
     3421 aaatcctgac cgcccgcctg cttttggcgg cagacagccg tttttcgcaa acccgccgac
     3481 aactcggcat ttcttcagat atgcacgact acagccgaac catgttcgtc tgccgcatga
     3541 aacatactct ttccaaccaa cataccgctt acgaatgctt ccattacggg cgcaccatcg
     3601 cactgctgcc gctggaagaa cacctgacca ataccgtcat taccgtcgat accgataaaa
     3661 tcaacagcgt tcaaaacctt tcgcccgaag aattggcggc aagcgtaaaa gaacagctca
     3721 agggcaggct cggcgatatg gaattggtca gcagcatcca ccattacccc cttgtcggta
     3781 tgattgccaa acgtttctac ggcaaacgca gcgcgctgat cggcgatgcg gctgtcggta
     3841 tgcaccccgt taccgcacac ggtttcaact tgggtctgtc cagcgcagat attttggcaa
     3901 aactgatact cgaagccgag cagcgcggtc aggacatcgg cgcggcttcc ttgttggaaa
     3961 aatacagcag caaacatatg ctgcatgccc agccgcttta tcacggaacc aatatgatgc
     4021 tgaaactgtt taccaatgag accgcgccgg caaaactgct gcgcggtttg gtattgcgtg
     4081 ccggcaacaa cttcccgccg ctgaaaaaac tgattaccaa acaactgacc ggttgaaaac
     4141 tgccgaaatg ccgtctgaaa cgtttcagac ggcatttttg tattatagtg gattaacaaa
     4201 aatcaggaca aggcgacgaa gctgcagaca gtacaaatag tacggaaccg attcacttgg
     4261 tgcttcagca ccttagagaa tcgttctcta tccttggcag acggtttgca gcagattcgc
     4321 atacggcaga tgtttcaagc ggaaaggaaa cacgataaaa ataaaaaagc ctccgaacag
     4381 tcggaggctt tgctttcaaa ctgaaattat ttcagtttgg tttctttgta cactacgtgt
     4441 ttgcgggcaa ccggatcgaa ttttttgatt tccagtttgc cgggcatagt gcgtttgttt
     4501 ttggtagtgg tgtagaagtg accagtacct gcactggatt ccagtttgat tttatcgcgc
     4561 attgcagtaa tccttaatta aatagtgttt aaattaagct tcgccgcgag cacgcaaatc
     4621 agccaatacg acatcaatgc ctactttgtc gatggtacgc agtgcagcgt tggaaacgcg
     4681 caggcgaacc cagcggtttt cactttctac ccaaaaacga cgtgattgca agttgggcaa
     4741 aaaacggcgt ttggttttgt tgttggcgtg cgatacgttg ttgccggaca tcgggcgttt
     4801 gccggtcact ttgcaaactc gtgccataat cagtctccaa acttctaaaa tagtaaaacg
     4861 cgatttatac cacgaaaaac agtgttagtt caagtgtttt aaagaaaaac ggctgttttg
     4921 cgcggataat ccttccgatt gtcgcatctg tggaacgttt gcaggtgcga aacagatggg
     4981 gcgcgattat agcggatttc gggaactgct gcattcaaaa tgccgtccga acatatttcc
     5041 agtattttca gacggcattt caagttttca aatccctcaa tgtccaccgc cgccactgct
     5101 gtggaacggc ggttttgcca gccatatgac gggtatcatg ataatgaata acaagctgcc
     5161 tgccataaag atttcattcg atccgatgat gaagccctgc tgggtaatgg tattgttgat
     5221 gatacctagg gtttgaatgt cggaaatgcc ttgttgggac aaatgcgccg ccgtttcgtg
     5281 caatgttgcg gaatagggcg tgatgtgttc ggcaaagcgc gtgtggtgca acgcttcgcg
     5341 ccgttcccac agggtgctga cgacggatac gccgacaccg cccatcagca cgcgcaggaa
     5401 attcgacagg ctgccggcgg cggcaatctg cccgcccttc atgtgcgaca gtgtgatggt
     5461 ggtcagcggc aggaagaaca tggcaacgcc tgccccctgc caaaactgcg gccagatgac
     5521 gttgccgata tccatgtcgg cataaaaatc ggtgcgccaa tagaaagtaa aggcaaaggt
     5581 caggaagctg gcggttacga gcaggcgcat atcgatttta ttgccgaacc tgccgattaa
     5641 cggagacagg aagacgggca ggatgccgac gggtgcggcg gcaagccccg cccacgtgga
     5701 ggtatagccc aggttggtct gcaacactaa cggcagcaag gtcagcgtcc ccatatacac
     5761 cataaaaccc aatgatgtgg caattacgcc gacggtaaaa ttccgatctt taaacagcga
     5821 taaatcgaca atcggatatt tttctcccaa ttcccaaaca ataaaatacg acaaacacac
     5881 cagtgcgact acgcccaagg taatgatttc tccagaggcg aaccagtcga gttccttacc
     5941 cctgtccagc atcatctgta acgcgccgat accgactacc atcaatgtaa gcccgacata
     6001 gtcggtcggc attttaacgg tttccgtttc ccgatatttc aaatgtttcc atgtaatcca
     6061 tgccgatatg ataccgatag ggatattaat gaagaaaatc caaccccaat gccagtttcc
     6121 ggaaatccaa ccgccgagta tcggcccgag aacaggggcg acaacgacgg tcattgccca
     6181 caatgccagt gccagcgtcc gttttgcggg cggataggat gccattaaca ggctttgcga
     6241 caggggaatc agcggcccgg cgataaagcc ctgcaagatg cggaaaatta ccaaagcctg
     6301 aaggttgggc gcgatgccgc acagccacga tgtgatgacg aaaccgacag cggcggcggt
     6361 aaacaatttg acctcgccga tacgttttgc caaaaagccc gttaacggca cggaaacggc
     6421 gtttgccaca gcaaaagaag taatgaccca cgtcccctgc gtggttgccg caccgaggtt
     6481 gccggcgatg acgggaacgg cgacattggc gatagtcgta tctaaaactt ccataaatac
     6541 ggcaagcccc aaagacagcg taacccacgc caatgccgca cccttaagcg gtggataatc
     6601 cattgtgtcc tccgtttcag acggcatcag ggcgcggatt gcccgaggat ttcatcgacc
     6661 gtccgatcga cttccgacca gtcggtactt tccatttccg gcaatgccgc acccggcgtt
     6721 tttgaaacag gcgcgcctgc ggcggaagta tccactttaa ccgtcatcga caaaccgata
     6781 cgcaacggat gcctgtccac atcttcgcgg ttcagcacga tacggacggg gacgcgctgc
     6841 accactttaa tccagttgcc cgttgcgttt tgcgccggaa tcagcgaaaa cgcgctgccc
     6901 gtacctgccg aaaaacctgc caccctgccg cgataaacaa tttgtttgcc gtacaaatcg
     6961 gacaccagct cggcaggctg tccgattttc atatgccgca actgcgtctc tttaaaatta
     7021 gcatccaccc acacatccga cagcggcacc accgccatca gcggcgcgcc tgccgccacc
     7081 tgctgcccga cctgcaccga acgcttcgcc acctgaccgt ccgccggcgc gcggatttgc
     7141 gtccgctgaa ggttcaacca cgcatctttc aacctgccga ttgccgtctg aaccgccggc
     7201 tgttcgcgca aagaaacctg accgcccaaa gccgcacgtg ccgaagactc ttccgccaaa
     7261 gccgccttaa ctgccgcctg agcctgagac actgccgcac gggcatgtgc cagctcttcg
     7321 gcggacactg cgcccgattc cgctaaagca gaccggcggc gtaaatcatc ctgcgcacgt
     7381 gccaaatccg ctcggcgcaa agcaacctgc gcccccgcct gagaagtggc ggcattttgc
     7441 tggcggtttt gccgcaccgc ctgaatcagc tcgttttttg cccgctcgta agccagcaca
     7501 tcattatcgt cgtccaacac cgccagcacg tcgccttttt tcacggcatc cgtatcgtcg
     7561 tgcaaaacct tccgcaccgt accgcccttt tgcggcgtaa cctgaaccac gcgtccggca
     7621 acataagcgt cttccgtttc ctcttcgtgc tgccaccata aaaaaaacgc cgacccggcg
     7681 gctgcggcgg caagcgcgaa cagcagcgtc aatgccgtca ggcggcgttt gcgtttggct
     7741 tgcgtgtttt gaagttttgt ttcgtccgtg tgcgtatcca taagattggg ttccgaattt
     7801 cctgatttca tataaacaat gttctttcaa taggaagcag attctatatc cgcgcaataa
     7861 cgcaatcaag tcagtatttt agatgcaata ttcaaaaaac aacgcttcag gcggcaaaac
     7921 tgaaaatata tttcgtttat ataatggatt aacaaaaatc aggacaa
//
LOCUS       DAXIDM010000090         7932 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000090 DAXIDM010000000
VERSION     DAXIDM010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7932
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.090"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(15..3230)
                     /gene="carB"
                     /locus_tag="ACFOAE_001624"
     CDS             complement(15..3230)
                     /gene="carB"
                     /locus_tag="ACFOAE_001624"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003749610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFC6885081.1"
                     /translation="MPKRTDLKSILIIGAGPIVIGQACEFDYSGAQACKALREEGYKV
                     ILVNSNPATIMTDPEMADVTYIEPIMWQTVEKIIAKERPDAILPTMGGQTALNCALDL
                     ARNGVLAKYNVELIGATEDAIDKAEDRGRFKEAMEKIGLSCPKSFVCHTMNEALAAQE
                     QVGFPTLIRPSFTMGGSGGGIAYNKDEFLAICERGFDASPTHELLIEQSVLGWKEYEM
                     EVVRDKNDNCIIICSIENFDPMGVHTGDSITVAPAQTLTDKEYQIMRNASLAVLREIG
                     VDTGGSNVQFAMNPENGEMIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGFTLDE
                     LRNDITGGKTPASFEPSIDYVVTKIPRFAFEKFPAADDRLTTQMKSVGEVMAMGRTIQ
                     ESFQKALRGLETGLCGFNPRSSDKAEIRRELANPGPERMLFVADAFRAGFTLEEIHEI
                     CAIDPWFLAQIEDLMKEEKAVSDGILSDLDFAALRRLKRKGFSDKRLAQLLNVSEKEV
                     REHRYALKLHPVYKRVDTCAAEFATETAYLYSTYEEECESRPSDRKKVMILGGGPNRI
                     GQGIEFDYCCVHAALALRESGFETIMVNCNPETVSTDFDTSDRLYFEPLTLEDVLEIV
                     RTENPWGVIVHYGGQTPLKLANALVENGVNIIGTSADSIDAAEDRERFQKVLNDLGLR
                     QPPNRIAHNEEEALVKAEEIGYPLVVRPSYVLGGRAMQIVHSAEQLQKYMREAVQVSE
                     DSPVLLDFFLNNAIEVDVDCVSDGKDVVIGGIMQHVEQAGIHSGDSGCSLPPYSLSEE
                     IQDEIRRQTKAMAYALGVVGLMNVQFAVQDGVVFVLEVNPRASRTVPFVSKATGVPLA
                     KVGARCMAGISLKEQGVEKEVVPDFYAVKEAVFPFIKFPGVDTILGPEMRSTGEVMGV
                     GASFGEAYYKAQLGAGERLNPTGKIFLSVREEDKERVIKTAKNFQALGYGICATRGTA
                     QYLTEHGLIVQTINKVPEGRPHIGDALKNGEIALVVNTVSSDPQSVSDSHIIRQSALQ
                     QRVPQYTTTAGGEAMSEGAKSRDHLGVYSVQELHGRLKNRN"
     gene            complement(3237..3785)
                     /locus_tag="ACFOAE_001625"
     CDS             complement(3237..3785)
                     /locus_tag="ACFOAE_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885082.1"
                     /translation="MRTIFFSGSRSISRLNPQIRERINNILSNNFDIVIGDANGADKA
                     IQKFLQEQDYANVHIYFSGKIYRNNVGNWQFVQVDSKGTGRVFYTAKDKKMAEIADYG
                     FILWDGKSIGSLNNIAELLQLNKPSLVYHSQTKEFFKIKSSADLENILSNIEDDVLAS
                     ILEKGNTFLKSYVTKQPSLIQE"
     gene            complement(3788..4351)
                     /locus_tag="ACFOAE_001626"
     CDS             complement(3788..4351)
                     /locus_tag="ACFOAE_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFC6885083.1"
                     /translation="MAIELNGNWTKGFALDHHMQKSILLGYDELGHPHFDSKRSVIGE
                     WVYQLKYRNQTQNVSLLVDYILQKFSGLESINLIVPAPFTTERINQPVQLIAKELSDR
                     LNIPYSPILRKSSSHTPLKNIEEKSEKLEILNNSITIDNIDLSNKNILVIDDLFDSGA
                     TLEISTEKLFSKNARSVIVLAMTKTRG"
     gene            complement(5033..5200)
                     /locus_tag="ACFOAE_001627"
     CDS             complement(5033..5200)
                     /locus_tag="ACFOAE_001627"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885084.1"
                     /translation="MADFDWIIENNRIKPTELSIYKGRLKNKKQPAQPVFPAEPLIPT
                     AAPSSLPVGKR"
     gene            complement(5204..5593)
                     /locus_tag="ACFOAE_001628"
     CDS             complement(5204..5593)
                     /locus_tag="ACFOAE_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HFC6885085.1"
                     /translation="MSTHEKLLTADNPVLHQRAKAMRQEMSEAEAKLWQHLRAGRLNG
                     YKFRRQQPMGNYIVDFMCVTPKLIVEADGGQHTEQAAYDHARTAYLNSLGFTVLRFWN
                     HEILQQTNDVLTEILLVLQELEKQAAR"
     gene            complement(6187..6312)
                     /locus_tag="ACFOAE_001629"
                     /pseudo
     CDS             complement(6187..6312)
                     /locus_tag="ACFOAE_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016687733.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(6358..7491)
                     /gene="carA"
                     /locus_tag="ACFOAE_001630"
     CDS             complement(6358..7491)
                     /gene="carA"
                     /locus_tag="ACFOAE_001630"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HFC6885086.1"
                     /translation="MSTPALLVLADGSVFHGTSIGYEGSTSGEVVFNTSMTGYQEILT
                     DPSYCKQIVTLTYPHIGNTGTNAEDEESRSVYAAGLIIRDLPLLHSNFRASESLHDYL
                     VRNKTVAIADIDTRRLTTLLREKGAQGGAILTGADATIEKAQELIAAFGSMVGKDLAK
                     EVSCTETYEWTEGEWELGKGFVTPDEQPYHVVAYDFGVKTNILRMLASRGCRLTVVPA
                     QTSAQDVLALNPDGVFLSNGPGDPEPCTYAIEAVQKLMESGKPIFGICLGHQLISLAI
                     GAKTLKMRFSHHGANHPVQDLDSGKVVITSQNHGFAVDADTLPANARITHKSLFDNTL
                     QGIELTDKPVFCFQGHPEASPGPQDVGYLFDKFIGNMKAAKRA"
BASE COUNT         1734 a         2018 c         2080 g         2100 t
ORIGIN      
        1 acctgattca ggtatcagtt gcggtttttc aaacgcccgt gcaactcttg aacgctgtac
       61 acgcccagat ggtcgcggct tttcgcgcct tcgctcatcg cttcgccgcc ggcagtggtg
      121 gtgtattgcg gcacacgttg ctgcaatgcg ctttggcgga tgatgtggct gtcggacacg
      181 gattgcggat cgctggaaac ggtattcacg accagtgcga tttcgccgtt tttcagcgcg
      241 tcgccgatgt gcgggcggcc ttcggggact ttgttgatgg tctgcacaat tagcccgtgt
      301 tcggtcaggt attgcgccgt gccgcgcgtg gcgcagatgc cgtagcctaa ggcttggaag
      361 tttttggcgg ttttaatgac gcgttctttg tcttcttcgc gcacggagag gaagattttg
      421 ccggtcgggt tgaggcgttc gcccgcgccg agttgggctt tgtagtaggc ttcgccgaag
      481 cttgcgccca cgcccatgac ttcgccggtg gagcgcattt ccggacccaa aatcgtatcc
      541 acgcccggga atttgatgaa ggggaacacg gcttctttaa cggcatagaa atcggggaca
      601 acttcttttt ccacgccttg ttctttcagg gagatgcctg ccatgcagcg cgcgccgact
      661 ttggcgagcg gcacgccggt ggctttggag acgaagggca cggtgcggct ggcgcgcggg
      721 ttcacttcca atacgaacac tacgccgtcc tgcacggcaa actgcacgtt catcagtccg
      781 accacgccca gcgcgtacgc catcgctttg gtttggcggc ggatttcgtc ttggatttct
      841 tcgcttaagg agtagggcgg cagcgagcag ccggagtcgc cggagtggat gcccgcctgt
      901 tcgacgtgct gcatgatgcc gccgataacc acatctttgc cgtctgaaac gcagtccaca
      961 tcgacttcaa tcgcgttgtt caggaagaag tcgagcaaca cggggctgtc ttcggaaacc
     1021 tgcacggctt cgcgcatata tttttgcaac tgctcggcgg agtggacaat ctgcatcgcg
     1081 cgtccgccca aaacataaga cgggcgcacg accagcggat aaccgatttc ttcggctttg
     1141 acgagtgctt cttcttcgtt gtgggcgatg cggttgggcg gctggcgcag gcctaagtcg
     1201 ttcaacactt tttggaagcg ttcgcggtct tcggcggcgt cgatgctgtc ggcggacgtg
     1261 ccgatgatgt ttacgccgtt ttcaaccaac gcgttggcga gtttcagcgg ggtttgaccg
     1321 ccgtaatgca caatcacgcc ccacgggttt tcggtgcgga cgatttccaa cacgtcttcc
     1381 aatgtcagcg gctcgaaata gaggcggtcg ctggtgtcga agtcggtgga cacggtttcg
     1441 gggttgcagt tgaccatgat ggtttcaaag cccgattcgc gcagggcgag tgcggcgtga
     1501 acgcagcagt agtcaaactc gatgccctga ccgatgcggt tcgggccgcc gccgagaatc
     1561 atcacttttt tacggtcgga aggacgggat tcgcattcct cttcgtaagt ggagtagagg
     1621 taggcggttt cggtggcaaa ctcggcggca caggtgtcga cgcgtttgta aaccggatgc
     1681 agcttcagcg cgtagcggtg ttcgcgaact tctttttcgc ttacgttcaa caattgtgcc
     1741 aaacgtttgt cggagaagcc tttgcgtttc agacggcgta gggcggcgaa atccaaatca
     1801 ctcaaaatgc cgtctgaaac cgctttttct tccttcatca agtcttcgat ttgcgccagg
     1861 aaccaagggt cgatggcgca gatttcgtgg atttcttcca gcgtgaagcc ggcgcggaac
     1921 gcgtctgcca caaacagcat acgctcaggg ccggggttcg ccagttcgcg gcggatttcc
     1981 gctttgtcgg agcttctcgg attgaagccg cacaagccgg tttccaagcc gcgcaaggct
     2041 ttttggaagc tttcctgaat cgtgcggccc atcgccatca cttcacccac cgatttcatc
     2101 tgtgtggtca ggcggtcgtc tgcggcaggg aatttttcaa acgcgaaacg cgggattttg
     2161 gttacgacat agtcgatgga cggctcgaac gacgcggggg ttttgccgcc ggtgatgtcg
     2221 ttgcgcaact cgtccagcgt aaagccgacc gccagcttgg ccgccacctt cgcaatcggg
     2281 aagcccgtcg ctttggaagc cagcgcggac gaacggctca cgcgcgggtt catctcaatc
     2341 acaatcatct cgccgttttc agggttcatc gcaaactgca cgtttgagcc gcccgtgtcc
     2401 acgccgattt cgcgcaatac cgccaacgaa gcgttgcgca tgatttggta ttccttgtcc
     2461 gtcagcgttt gcgccggcgc gaccgtaatc gagtcgcccg tatgcacgcc catcgggtcg
     2521 aagttttcaa tcgagcagat gatgatgcag ttgtcgttct tgtcgcgcac tacttccatc
     2581 tcgtactctt tccagccgag aacggactgc tcaatcagca gctcgtgcgt gggcgaggca
     2641 tcgaaaccgc gttcgcaaat cgccaaaaac tcgtctttat tgtaggcaat gccgccgccc
     2701 gaaccgccca tcgtgaaaga aggacgaatc agggtaggga agccgacctg ttcttgcgcc
     2761 gccaaagctt cgttcatggt gtggcagaca aaagatttcg ggcaggagag gccgattttt
     2821 tccatcgctt ctttaaaacg accgcggtct tccgccttgt caatcgcgtc ttccgtcgcg
     2881 ccgatcagct cgacattgta tttcgccagc acgccgttgc gtgccaaatc cagcgcacag
     2941 ttcagcgcgg tctgaccgcc catcgtgggc agaatcgcat caggccgctc cttggcgata
     3001 atcttctcca ccgtctgcca cataatcggc tcgatgtagg taacatccgc catttcaggg
     3061 tcggtcataa tcgtggcggg gttggaattc accaaaatga ctttatagcc ttcttcacgc
     3121 aaagccttgc aggcctgtgc gcccgaatag tcaaattcgc aggcctgacc gataacgata
     3181 gggccggcgc cgatgataag gatggatttt aggtcggtac gtttgggcat gggtggttac
     3241 tcttgaatta aagaaggttg ttttgttaca tagcttttaa gaaaagtatt tcccttttct
     3301 aaaattgaag ctaaaacatc atcttctatg ttagataaaa tattctctaa atctgcgctt
     3361 gatttaattt taaagaattc ttttgtttga gaatggtata caagagaagg tttatttagc
     3421 tgtaaaagtt ctgctatatt atttaatgaa ccaatactct taccatccca taaaataaag
     3481 ccataatcag caatttctgc cattttctta tcttttgctg tataaaatac ccttccagtt
     3541 cctttgctgt ctacttggac aaactgccaa ttccccacat tatttcggta aattttgcca
     3601 gaaaagtaaa tatgcacatt agcataatct tgttcttgta gaaatttttg gatagcttta
     3661 tcagccccat tagcatctcc aataacaata tcaaaattat tgctaagaat attgttaatt
     3721 ctttctcgta tttgtggatt tagtcgtgaa atgctgcgtg aaccagaaaa gaaaatagtg
     3781 cgcattttta tcctctagtc tttgtcattg ctaaaacaat tacagatcta gcattttttg
     3841 aaaacaattt ttcagttgat atttccaatg ttgctccgct atcaaataaa tcatcaatta
     3901 ctaaaatatt cttattggat agatctatat tgtcaattgt gatggaatta ttcagtattt
     3961 ctagtttttc tgatttttct tcaatatttt tgagtggtgt gtgtgagcta gattttctta
     4021 aaataggaga atatggaata ttcaagcgat cacttagttc tttggcaatt aattgaactg
     4081 gttgattaat acgctctgtt gtaaaagggg cgggaacaat taaatttata gattctaaac
     4141 cactaaattt ttgtaaaata tagtctacca gcaaagaaac attttgggtt tgattacgat
     4201 attttaattg ataaacccat tctccaatca cacttctctt gctatcaaag tgaggatgcc
     4261 ctaattcatc ataacctaac aaaatacttt tttgcatatg atggtctaaa gcaaatcctt
     4321 ttgtccagtt accatttagt tctatcgcca tttcattgac tccttgtcaa aattaagtat
     4381 aacgagcaat cctagcaagc cgtagcccgc atgtagggta tgtgcggtac gtacgcacgc
     4441 gttctccatt ttccctgcaa ccccaaccca ccgtgtgcgt gccttgcggc acactctctg
     4501 ccgacggatt caaaggtcgt ctgaaaaaac gctcgcggca tttgttccat cttccttgcg
     4561 ataaaggcta cctgaaaaat tcctgctgtt gatatctcgg gcattctttc tcaaaccgcc
     4621 tgtaaccgca aaacttgctg caacctaccc cctcccccgt gggggagggc tggggagagg
     4681 gcattctccg aatttcggca acctttccca acaactcaac caccgaaata caagccttgt
     4741 ggcttgttgc cctctctcta gctctctccc acgggagaga ggacggagtg gctgtagggc
     4801 taagggttct gcaaggaaac aggttgtgca ggttgctttt tgcttttcag acgacctgaa
     4861 atcaacggta aatccaagtc gcttttcaaa ccgcctgtaa ccgcaaaact tgctgcaacc
     4921 taccccctcc cccgtggggg agggctgggg agagggcatt ctccgaattt cggcaacctt
     4981 tcctaacact ctaaccgcca agacacaagc cttgcggctt gttgccctct ctctaacgct
     5041 ttcccacagg gagagaggac ggggcggctg ttggaattaa gggttctgca ggaaaaacag
     5101 gttgtgcggg ctgttttttg tttttcagac ggcctttata aatgctcaat tcagtcggct
     5161 ttatcctatt attttcaata atccaatcaa aatcagccat ctgctatcgt gcagcttgct
     5221 tttccaattc ttgcaacacg agcaggattt ctgtcagcac atcgtttgtc tgctgtaaaa
     5281 tctcgtgatt ccaaaaccgc agtacggtaa agcccaagct gttgagatat gccgtccgcg
     5341 cgtggtcgta tgcggcttgt tctgtgtgct gccctccgtc tgcttcgaca atcaacttgg
     5401 gcgttacgca cataaaatca acaatatagt ttcccatcgg ctgctggcgg cggaatttat
     5461 agccgttcag acgacctgcc cgcaggtgct gccacaattt tgcttccgcc tcgctcattt
     5521 cttggcgcat ggctttggcg cgttgatgca ggacggggtt gtcggcggtt aaaagtttct
     5581 cgtgcgtgct cattctgttg tcgggttact gtttgtgtaa gccttacagt ttgttgccct
     5641 ctctctgact ctctcccatg ggagagagga cggggcggtt gttggggtta aaggggctgt
     5701 aaggaaaaca agtcgttcag gccacttttt acttttcaga cgacctgcaa tcaacggttg
     5761 taaatccaag ttgcttttca aaccgcctgt aaccgcaaaa cttgctgcaa cctaccccct
     5821 cccccgtggg ggagggctgg ggagagggca ttctccgaat cgaggcaatc tttccctaat
     5881 tccctaactg cctcaataca agcctttcgg cttgttgccc tctctctaac gctttcccac
     5941 agggagacag gacggggcgg ctgtagtgat taagggtttt gcaaggaaaa caaggaaaac
     6001 aagttgtaca ggctgttttt tatttttcaa gcgacctgaa atcaacgctt gtaaatccaa
     6061 gtcgcttttc aaactgcctg caaccgcaaa atctgctgca acctaccccc tcccccgtgg
     6121 gggagggctg gggagagggc attttccaag ttgcggcaat ctttcccaaa tcccttagtc
     6181 ttctaaaata caagccttac ggttgttgcc aaatgaaact tcttccatac ccaaaacttg
     6241 cgtgtaaaac gcaatggttc ggtcaatgtc ggcaacggtc agtaccagat ggtcgagtgc
     6301 gctaatcttc atttcccgct ttctttttca ggcggcggca gtgccgtctg aaagccatta
     6361 tgcccgtttt gccgctttca tattgccaat gaatttgtca aacaaatagc cgacatcttg
     6421 cggaccgggg ctggcttcgg ggtggccttg gaagcagaac acgggtttgt cggtcagctc
     6481 gatgccttgc aaagtgttgt caaacaagga tttgtgggta atgcgtgcgt tagcgggcag
     6541 ggtgtcggca tcaacggcaa aaccgtggtt ttggctggtg atgacgactt tgccgctgtc
     6601 caaatcttgc acagggtggt tcgcaccgtg gtggctgaag cgcattttca gggttttcgc
     6661 gccgatagcg aggctgatga gctggtgtcc caagcagatg ccgaaaatcg gtttgccgct
     6721 ttccatcagt ttttgcacgg cttcgatggc gtaggtgcaa ggctcggggt cgccggggcc
     6781 gttggacagg aacacgccgt cgggattgag tgccaacacg tcttgtgcgc tcgtttgggc
     6841 ggggacgacg gtcaggcggc agccgcgcga ggcgagcata cgcaggatgt tggttttcac
     6901 gccgaaatcg taggcgacga cgtggtaagg ctgttcgtca ggggtaacga aacccttgcc
     6961 caattcccat tcgccttccg tccattcgta agtttccgtg caggaaactt cttttgccaa
     7021 gtctttgccg accatactgc cgaacgcggc gatgagttct tgcgcttttt cgattgtggc
     7081 atccgcaccg gtcagaatcg cgccgccttg cgcgcctttt tcgcgcaaca gcgtggtcag
     7141 gcggcgggta tcgatgtcgg cgatggcgac ggttttgttg cgtaccagat agtcgtgcag
     7201 gctttcggag gcgcggaagt tgctgtgcaa gagcggcagg tcgcggataa tcaggccggc
     7261 ggcataaacg ctgcggcttt cttcatcttc ggcgttggtg ccggtgttgc cgatgtgtgg
     7321 gtaggtgagg gtaacgattt gtttgcagta ggacgggtcg gtcaggattt cctgatagcc
     7381 agtcatcgaa gtattgaaca cgacttcgcc ggaagtcgaa ccttcgtaac cgattgatgt
     7441 gccgtggaat acgctgccgt cagcgaggac gaggagggcg ggggtgctca tgatgggaat
     7501 cctgttttta ataaaattct tgacaatgcc gtctgaaggg acttcggcag ggggcatccg
     7561 gtcggaaaaa tccggtcaaa aaaaaacacg ccgcgcaaga tagacgcgta acgtgctttt
     7621 cgggcaagtg cctataccct gaaagcagca tattttaaga cgaaacatac ccgatttcaa
     7681 gcgcaaacgc ggcaggcggg ctgatatgtt cgcgcgaaaa cggaaatccg tggcgtaaaa
     7741 ccgcccgctc cgcgcccact atgcccgtta cgcatttccc cacgtccgtc cggcgaaact
     7801 atgggaatac ccgaatcgtc aggaatacct gaatcgtcag gaatacccga accatcattc
     7861 ccgcgcaggc gggaatctag acctgtcggc acagaaactt atcgggtata acggtttctt
     7921 gagattccgc at
//
LOCUS       DAXIDM010000091         7927 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000091 DAXIDM010000000
VERSION     DAXIDM010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7927
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.091"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            331..1644
                     /locus_tag="ACFOAE_001631"
     CDS             331..1644
                     /locus_tag="ACFOAE_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HFC6885087.1"
                     /translation="MLTFIGLLIIGVIVWLLLTEKVSPIIALILVPLFGALLAGFDVS
                     QLKEFYSGGTKSVMQIVIMFMFSILFFGIMNDVGLFRPMIGGLIKLTRGNIVAVSVGT
                     VLVSVVAQLDGAGATTFLLVVPALLPLYKRLHMNPYLLFLLLTSSAGLINLLPWGGPT
                     GRVASVLGADVGELYKPLLTVQIIGVVFILALSLLLGVREKRRIVRELGALPAVADLI
                     KPVPLSEEEQKLARPKLFWWNVLLFLAAMSLLFSGIFPPGYVFMLAATAALLLNYRSP
                     QEQMERIYAHAGGAVMMASIILAAGTFLGILKGAGMLDAISKDIVHILPDALLPYLHI
                     AIGVLGIPLELVLSTDAYYFGLFPIVEQITSQAGVAPEAAGYAMLIGSIVGTFVTPLS
                     PALWMGLGLAKLSMGKHIRYSFFWAWGLSLAILASSIAAGIVPLP"
     gene            1867..2042
                     /locus_tag="ACFOAE_001632"
                     /pseudo
     CDS             1867..2042
                     /locus_tag="ACFOAE_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003692565.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
     gene            2662..3360
                     /locus_tag="ACFOAE_001633"
     CDS             2662..3360
                     /locus_tag="ACFOAE_001633"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFC6885088.1"
                     /translation="MTALSLQAERLNNMSLPPDAARQSAVLQQSIRRNKHLLEQLLAL
                     ARSQSDETPLAKTTFGLQSRFRQVLQELMPLALEKRQDIGVAVGGDVEIFADETEIYT
                     LVKTFVDNAIRYTPSEGRIDLGFTDEGKYLAVWVEDNGNGIPESERARVLDPFYRILG
                     TEQQGTGLGAVDCRHACQKIRRTFGIDRQPTFRTRSVDTRVVGQGNPEIDRCRLKASD
                     GIFYISTISYCSCV"
     gene            complement(3324..4817)
                     /gene="rng"
                     /locus_tag="ACFOAE_001634"
     CDS             complement(3324..4817)
                     /gene="rng"
                     /locus_tag="ACFOAE_001634"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HFC6885089.1"
                     /translation="MLSGLPIPKDIARPPETILVNITPQETRVAVLEENNICELHIER
                     NSEHSLVGNIYLGVVRRVLPGMQSAFIDIGLERAAFLHIVDVLEQRRNPEETQRIEHM
                     LFEGQSVLVQVIKDPINTKGARLSTQISLAGRFLVHLPQEDHIGVSQRIEDDAERSSL
                     RERLDKLLPENACRGYIIRTNAENATDEQLQSDIDYLTKVWEHIQEQAKIRPPETLLY
                     QDLPLSLRVLRDMVGCDTQKILVDSTVNHGRMTRFAEQYVHGALGRIELFKGERPLFE
                     THNVEQEISRALQPRVNLNFGSYLIIESTEAMTTIDVNTGGFVGARNFDETIFRTNLE
                     ACHTIARELRLRNLGGIIIIDFIDMAQESHREAVLQELAKALAFDRTRVTLHGFTSLG
                     LVELTRKRSRENLNQVLCEPCPSCQGRGRLKTPQTVCYEIQREIVREARRYDAESFRI
                     LAAPNVIDLFLDEESQSLAMLIDFIGKPISLAVETAYTQEQYDIVLM"
     gene            5031..5288
                     /gene="grxC"
                     /locus_tag="ACFOAE_001635"
     CDS             5031..5288
                     /gene="grxC"
                     /locus_tag="ACFOAE_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HFC6885090.1"
                     /translation="MQTVTMYTGPFCPYCAMAKRLLHAAGVGHIDEIRVDASPEAFAE
                     MQQLSGQRSVPQIFIGETHVGGFTDLYRLQQEGGLDGLLNP"
     gene            5309..5752
                     /gene="secB"
                     /locus_tag="ACFOAE_001636"
     CDS             5309..5752
                     /gene="secB"
                     /locus_tag="ACFOAE_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HFC6885091.1"
                     /translation="MSEELQPVFSIERLYVKDLSLEVPHAPQIFLEQGEPEVDMRVST
                     GSQKLEDGYYNVDVTVTVTAKLDNERTMFLNEVTQSGIFRLENIPEEDVQLLLGVACP
                     NILFPYAREAVSGTVTRAGFPPVLLAPINFEAIYQQQQEAEAAGA"
     gene            5838..7880
                     /gene="recG"
                     /locus_tag="ACFOAE_001637"
     CDS             5838..7880
                     /gene="recG"
                     /locus_tag="ACFOAE_001637"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFC6885092.1"
                     /translation="MMSPETQKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETH
                     IMPIKDAPIGVPCQVEGEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQ
                     TAIGKRIRAVGEIKHGFYGDEMIHPKIRDAEGGGLAESLTPVYPTVNGLNQPTLRRII
                     QTALDVTPLHDTLPDALLCRLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKF
                     DELLAQQLSMRLARQKRIDGSAAALRGNGVLTQALRRALPFALTDAQEKVVSEICRDM
                     AQTYPMHRLLQGDVGSGKTIVAALSALTAIESDTQVAVMAPTEILAEQHFIKFKQWLE
                     PLGIEVVRLFGSLRKKAKDEAKAKLADGSVKIAIGTHALFSDGVAFHNLGLTIVDEQH
                     RFGVAQRLALKNKGREVHQLMMSATPIPRTLAMSFFADLDVSVIDKLPPGRTPIKTRL
                     VNNVRRAEVEGFVLGTCRKGRQAYWVCPLIEESETLQLQTAAETLARLQTALPELNIG
                     LVHGRMKAAEKAEVMARFSSGGLNVLVATTVIEVGVDVPNAALMVIEHAERMGLAQLH
                     QLRGRVGRGAAESVCVLLFAEPLGELAKARLKVIYEHTDGFEIARQDLNIRGPGEFLG
                     ARQSGVPMLRFAKLEEDLHLLEQARETAPMLIEQNPEIVEAHLARWLSGREGYLGV"
BASE COUNT         1659 a         2074 c         2331 g         1863 t
ORIGIN      
        1 cgccttgtcc tgatttttgt tcatccacta taaaatcccg cgtgtacggc acgccccgcg
       61 ctccgcaatg ataggggcgg tttcgtttga atcggcgtac cgggatgaat gcccccgcgc
      121 cgtcccgata ccgatttgcc ggttgttccg tatcggttgc cgccgtgaaa tgacggacgg
      181 atgcaggaat ggcggcaggc gtgaatggga ggaaatgacc gattgacttg tttcaaaata
      241 aaaaagtaga atgcaaggct tatcccgcgt ctgtgggcgg ttttgcctgc acggtcggtt
      301 ttctgtttaa aataaaataa aggagaaatg atgctgacgt ttatcggact gctgattatc
      361 ggggtcatcg tatggctgct gctgacggaa aaagtgtcgc ccatcatcgc attaatcttg
      421 gtgccgctgt ttggggcgtt gctggcgggg tttgatgtat cccaattaaa agaattttat
      481 tcgggcggca ccaaatcggt gatgcagatt gtgattatgt ttatgttttc cattttgttt
      541 tttggaatca tgaacgatgt ggggctgttc cgtccgatga taggcggttt gattaagctg
      601 actcggggta atatcgtggc agtgagtgtg gggacggtct tggtgtcggt ggtggcgcag
      661 ttggacgggg cgggtgcgac gacgttttta ttggtcgtcc ccgccctttt gccgctttac
      721 aagcgtctgc atatgaatcc ttacctgctg tttttgctgc tgacttccag tgcgggattg
      781 attaaccttc tgccgtgggg cgggccgacc gggcgggttg caagcgtgtt gggcgcagat
      841 gtgggcgaat tgtataaacc tttgttgacg gtgcaaatta tcggtgtggt gtttatcctt
      901 gcgctgtccc tgcttttggg tgtgcgtgaa aaaaggcgga ttgtccggga gttgggcgcg
      961 ttgcccgccg tggcggattt gataaagccg gtgcctttgt cggaagaaga acaaaaattg
     1021 gcgcgtccga aactgttttg gtggaatgtc ctgctgtttt tggcggcgat gagcctgctt
     1081 ttttcgggca tcttcccgcc gggttatgta tttatgctgg ctgcaacggc ggcgttgctt
     1141 ttgaattacc gcagcccgca ggaacagatg gagcggattt atgcccacgc cggcggcgcg
     1201 gtgatgatgg cgtccattat tttggcggca ggtacgtttt tggggatttt gaagggtgcg
     1261 gggatgttgg acgcgatttc caaagacatt gtgcatatcc tgccggacgc gctgctgcct
     1321 tatctgcata ttgccatcgg tgtgttgggc attccgcttg agttggtttt gagtacggac
     1381 gcttattatt tcggactgtt tccgattgtg gagcagatta cctcgcaggc gggcgtggcg
     1441 cccgaagcag caggttatgc gatgttgatc ggcagtatcg tcggcacttt tgttacgccg
     1501 ctttcgccgg ctttgtggat gggcttgggt ttggcgaaat tgtcgatggg caaacacatc
     1561 cgttattcgt ttttttgggc gtggggtttg tcgctggcga tattggccag ttcgatagcg
     1621 gcaggaatcg tgcctctgcc gtaaacggcg aagccgtctg aagcccgaat cgttcctgtg
     1681 gtctgtcgca ggctctgcct gcctgcccgt gtgttgcaat cgcgccccaa tgccgtctga
     1741 aggcagttgc cggcgcggtt tttttgtgcc gcagttttga aaaataccgg caagcgtaaa
     1801 ggccgctaaa ttgcggctaa ttttggggtg ttagaatagg cacggtttat tttgaaggga
     1861 aagttgatgc gtgttttgct ggtggaagac gatgcgatga ttgcggaggc ggtgtcggca
     1921 agtttgaaag acggcggcta tgcggtggat tgggtcaaaa acggcgcgcg gctgccgctg
     1981 cccagcctta tgacttgatg ctgctggatt tgggtttgcc ggggcgggac ggtttggatg
     2041 tttgttccgc tggcaatgct tgcaggtatg ttttcctact acgaaacctt ccacgaaacg
     2101 gaagcgttgc aggacgacct gctccgtcag gcggcattgt acgtcggccc tgattccaaa
     2161 cccgaaactt tgcccgaggg cgacggcgat acgcgcattt tcgtgcagat gccgcagcag
     2221 gaagaccctg ttgtcagcct gcctgcgcat ctggcggacg gtctgcacac gcttcaggcg
     2281 gacggggacg acgattatta ccgcgtctat atccgcacga ccgaacaggg acggattgcc
     2341 gttatgcagg aaaacgaata ccgtgaagat ttggcggcgg atgcggcacg gcaaagcgtg
     2401 ttgcccctgt tggcggcact gccgctgatg attttgctga ccgtgtggat tacgcacaaa
     2461 gccatgcgcc ccgtccgcaa attgtcgcaa agtctcgaac aacgccgaat caatggcctg
     2521 tctgccttga gtgtggacaa tattcccagt gaaatcagag ggttcgtaac cgccatcaac
     2581 ttgcttttga aacgtgcgga tgaagacatc cgccaccgtc agcggtttgt cgccgacgcg
     2641 gcacacgaat tgcgtacgcc gatgacagcc ctttcccttc aggcggaacg gctcaacaat
     2701 atgtctctgc cacccgatgc ggcgcggcag tctgccgttt tgcagcaaag catacggcgc
     2761 aacaaacacc tgctcgagca gcttttggca ctggcgcgtt cgcagtcgga cgaaacccct
     2821 ttggcgaaaa cgacattcgg tctgcaaagc cgtttccgcc aagtgttgca ggaactgatg
     2881 ccgcttgcct tggaaaaacg tcaggacatt ggtgtggcgg tcggaggtga tgtcgaaata
     2941 tttgccgatg aaactgaaat ctataccttg gttaaaacgt ttgttgataa cgcaatacgt
     3001 tataccccgt ccgaaggcag gatagatttg ggtttcacag acgaagggaa atatcttgcc
     3061 gtgtgggtgg aagataacgg gaacggcatt cccgaatccg aacgcgcccg cgtcctcgat
     3121 ccgttttacc gtattttggg aacggagcag caggggacgg ggctgggggc tgtcgattgc
     3181 cgacacgctt gccaaaaaat acggcggaca tttggaattg accgacagcc gacgtttcgg
     3241 acacggtctg ttgatacgcg cgttgttgga caaggaaacc ctgaaataga cagatgccgt
     3301 ctgaaggctt cagacggcat tttttacatc agcacaatat cgtattgttc ctgcgtgtaa
     3361 gcggtttcga ccgccagaga aatcggtttg ccgatgaaat ctatcagcat tgccaaggat
     3421 tgcgattctt cgtccaaaaa caaatcgatg acgttggggg cggcgaggat gcggaaactt
     3481 tcggcatcgt aacggcgcgc ttcgcggacg atttcgcgct ggatttcgta gcacacggtt
     3541 tgcggcgttt tcagacggcc tctgccttgg caggaagggc agggttcgca gaggacttgg
     3601 tttaagtttt cgcgcgagcg tttgcgcgtc agctcgacca gccccaggct ggtaaaaccg
     3661 tgcagggtaa cgcgggtacg gtcgaaggcg agggctttgg caagctcctg caacacggct
     3721 tcgcggtggc tttcctgcgc catatcgatg aagtcgatga tgatgatgcc gccgaggttg
     3781 cgtagcctca attcgcgggc gatggtgtgg caggcttcga ggttggtgcg gaagatggtt
     3841 tcgtcgaagt tgcgtgcgcc gacgaagccg ccggtgttca cgtctatcgt ggtcatcgct
     3901 tcggtggatt cgataatcag gtagctgccg aagttgaggt tgacgcgcgg ttgcagggcg
     3961 cggctgattt cctgttcgac gttgtgggtt tcaaacagcg ggcgttcgcc tttgaacagc
     4021 tctatcctgc ccaatgcgcc gtggacgtat tgttcggcaa aacgcgtcat gcgcccgtgg
     4081 tttacggtgg aatcgacgag gattttctgc gtgtcgcagc cgaccatatc gcgcaatacg
     4141 cgcaaactca agggcaaatc ctgataaagc agggtttccg gcggccggat tttcgcctgt
     4201 tcttggatgt gttcccacac tttggtcagg tagtcgatgt cggactggag ctgttcgtcg
     4261 gtggcgtttt cggcgttggt gcggatgatg tagccccggc aggcattttc cggcaggagc
     4321 ttgtcgaggc gttcgcgcag gctgctgcgt tcggcatcgt cttcgatgcg ttgggacacg
     4381 ccgatgtggt cttcttgcgg aagatggacg aggaaacgcc ccgccagcga gatttgggtg
     4441 gaaagccgcg cgcctttggt gttgatcggg tctttgatga cctgcaccaa aacagactgc
     4501 ccttcaaaca gcatatgttc gatgcgctgg gtttcttcgg ggttgcggcg ttgttcgagg
     4561 acatcgacga tgtgtaaaaa cgccgcgcgt tccaagccga tgtcgataaa cgcgctctgc
     4621 atcccgggca gcacgcggcg caccacgccc agatagatat tgccgaccag gctgtgttcg
     4681 ctgttgcgct cgatgtgcag ctcgcagata ttgttttcct ccaacaccgc tacgcgcgtt
     4741 tcctgcggcg tgatgttgac caatatcgtt tcgggcgggc gcgcgatgtc tttggggatg
     4801 gggagtcctg acaacatggt ttttcctgaa aatgtaataa aaatattttt gcacccgttc
     4861 cgccgcgcag cgcgggtgca aaaatatttt tcacaatgcc tatcatactt taaaaaagaa
     4921 actttgacac attccgcaca tgccgtttga acgtgcatct gttccgcact tgccaaacag
     4981 gggaaatgcc cctatattga ttatcattgc aaaactttcg gaaacccaat atgcagaccg
     5041 ttaccatgta cacaggtccg ttttgtccct actgcgcgat ggcgaaaagg ctgctgcacg
     5101 cggcaggtgt cggacatatc gacgaaatcc gtgtcgatgc aagccccgaa gcctttgccg
     5161 aaatgcagca gctttcggga cagcgcagcg tgccgcagat tttcatcggc gaaacgcacg
     5221 tcggcggatt taccgacctc taccgcctcc agcaggaagg cgggctggac ggactgctga
     5281 acccttaacc cccaactagg aaaacaaaat gagcgaagaa ctgcaacccg tattcagcat
     5341 cgagcgactg tatgtcaaag acttgtcttt ggaagtgccg cacgcgccgc aaatcttttt
     5401 ggaacagggc gagcccgaag tggatatgcg cgtttccacc ggcagccaaa agctggaaga
     5461 cggctactac aacgtggatg taaccgttac cgtaaccgcc aaattggata acgagcgcac
     5521 gatgtttttg aacgaagtaa cccaaagcgg tattttccgt ttggaaaaca tccccgaaga
     5581 agatgtgcag ctgctgctgg gcgtggcgtg tccgaacatc ctcttccctt acgcgcgcga
     5641 agccgtttcc ggtacggtaa cacgtgccgg cttcccgccc gtcctgctcg cgccgattaa
     5701 ttttgaggcg atttaccaac aacagcagga agccgaagcc gccggggctt gattcctgcc
     5761 tgccgatgcc gtctgaatcc gtttcagacg gtatttttgt tttcggataa aataggtgcg
     5821 ttcaaaggaa tctgcctatg atgtcgcccg aaacccagaa acagctcaaa atcaccgatg
     5881 tttccgccaa gaagctcgac aaactcaacc tccataccgc atgggatttg gtgttgcacc
     5941 tgccgttgcg ttacgaggat gagacgcaca tcatgccgat taaggatgcg ccgatcggcg
     6001 tgccgtgtca ggtcgagggc gaagtcatcc atcaggaagt aacgttcaaa ccacgcaagc
     6061 agttgattgt ccaaatcgcc gacggctccg gcagcgtcct tttcctgcgc ttcatccact
     6121 tttacgccag ccatcagaag cagacggcga tcggcaaacg catccgcgcc gtgggcgaaa
     6181 tcaaacacgg cttttacggc gacgagatga ttcatcccaa aatccgcgat gccgagggcg
     6241 gcggtttggc ggaaagcctc acgcccgtct atccgaccgt aaacggcttg aaccaaccca
     6301 ctttgcgccg catcattcag acggcgttag acgttacgcc gctgcacgac acgctgcccg
     6361 atgccctgct gtgccgtctg aagctgccgc acctcgccga aagcctgcgt cttctgcact
     6421 cgccgccgcc gagtttcact atccatcaac tttcagacgg cacgctgccg gcgtggcaac
     6481 ggctcaaatt tgacgaactt ttggcgcaac agctttctat gcggctggcg cggcagaagc
     6541 gtatcgacgg ctcggcggcg gcattgcgcg gcaatggcgt attgacccaa gccctgcgcc
     6601 gcgccctgcc gtttgccctg accgatgcac aagaaaaagt tgtttccgaa atctgccgcg
     6661 atatggcgca aacctacccg atgcaccgcc tgctgcaagg cgatgtcggc agcggcaaaa
     6721 ccatcgtcgc cgccttgtcc gcgctgaccg ccatcgaatc cgacacgcag gtggctgtaa
     6781 tggcgcccac tgaaatcctt gccgaacaac attttattaa atttaaacaa tggctcgaac
     6841 ctttgggtat tgaagttgtc cgcctttttg gcagtttgcg taaaaaagcc aaagacgaag
     6901 ccaaagccaa actcgccgac ggcagcgtca aaatcgccat cggcacgcac gccctgtttt
     6961 cagacggcgt ggcgtttcac aatttgggct tgaccattgt ggacgaacag caccgtttcg
     7021 gcgttgccca acgcctcgcc ctcaaaaaca aagggcgcga agtccatcag ctgatgatgt
     7081 ccgccacgcc catcccgcgc acgcttgcga tgagtttttt cgccgatttg gacgtgtccg
     7141 ttattgacaa actgccgccc gggcgcacgc cgattaaaac gcgcctcgtc aacaacgtcc
     7201 gccgcgccga agtcgaaggc ttcgtcctcg gcacttgccg aaaagggcgg caggcgtatt
     7261 gggtctgccc attgattgaa gaaagcgaaa ccctgcaact gcaaaccgcc gccgaaaccc
     7321 tcgcccggct tcagacggca ttgcccgaac tcaatatcgg actggtacac gggcgcatga
     7381 aggccgccga aaaggccgaa gtgatggcgc ggttttcttc gggggggctg aacgtcttgg
     7441 tcgccaccac cgtcatcgaa gtcggcgtag atgtgcccaa tgccgccctg atggtcatcg
     7501 aacacgccga gcgcatgggc ttggcgcagc tgcaccaatt acgcggtcgg gtcgggcgcg
     7561 gcgcggcaga aagcgtgtgc gtcctcctgt ttgccgaacc cttgggcgaa ctcgccaaag
     7621 cgcggctgaa agtcatctac gaacacaccg acggctttga aatcgcccgc caagacctca
     7681 acatccgcgg ccccggcgaa tttctcggcg cgcgccaaag cggcgtgcct atgctgcgtt
     7741 tcgccaagct cgaagaagac ctgcacctct tggaacaagc gcgcgaaacc gccccgatgc
     7801 tgattgaaca aaaccccgaa atcgtcgaag cgcatttggc aagatggctt tccggcaggg
     7861 aagggtattt gggcgtgtga gcaaaatgcc gtctgaaata ttagaaaaaa aagtgtaacg
     7921 gaaatct
//
LOCUS       DAXIDM010000092         7847 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000092 DAXIDM010000000
VERSION     DAXIDM010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7847
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.092"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(90..1886)
                     /locus_tag="ACFOAE_001638"
     CDS             complement(90..1886)
                     /locus_tag="ACFOAE_001638"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFC6885093.1"
                     /translation="MNTVSNYLSALREAMKAQGLDALVIPSADPHLSEYLPEHWQARR
                     ELSGFTGSVGTFVVTADEAGVWVDSRYWEQAAKQLAGSGIELQKSGQVPPYNEWLAAN
                     LPENAAVGIPSDMVSLTGKRTLAQSLTAKNIRIEHPNDLLDQVWTSRPALPAETVFIH
                     DPAYVSETAAEKLARVRAVMAEKGADYHLVSSLDDIAWLTNLRGSDVPFNPIFVSFLL
                     IGKDNAVLFTEQCRLNAEAAAALQTAGIAVEPYAQVADKLAQIGGTLLIEPNKTAVST
                     LVRLPESVRLIEGINPSTLFKSCKSEADIARIREAMEHDGAALCGFFAEFEDIIGNGG
                     SLTEIDVDTMLYRHRSARPGFISLSFDTIAGFNANGALPHYSATPESHSTISGNGLLL
                     IDSGAQYKGGTTDITRVVPVGTPTAEQKRDNTLVLKAHIALAEAVFPENIPSPLIDAI
                     CRKPLWQAQCDYGHGTGHGVGYFLNVHEGPQRIAFAAPATPETAMKKGMVTSIEPGLY
                     RPGKWGIRIENLAANQAVATPQETEFGSFLCFETLTLCPIDTRLMDTALMTDGEIDWV
                     NRYHAEVRRRLEPLTEGAAKAWLIKRTEPLAR"
     gene            2343..3596
                     /locus_tag="ACFOAE_001639"
     CDS             2343..3596
                     /locus_tag="ACFOAE_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HFC6885094.1"
                     /translation="MSEQHISTWKSKINALGPGIMMASAAVGGSHLIASTQAGALYGW
                     QIALIIILTNLFKYPFFRFSAHYTLDTGKSLIEGYAEKSRVYLWVFLILCILSATINA
                     GAVAIVTAAIVKMAIPSLMFDAGTVAALIMASCLIILVSGRYRALDRVSKIIIVTLSI
                     ATLAAAGIAMSRGMQMQPDFIEPTPWTLAGLGFLIALMGWMPAPIEISAINSLWVTEK
                     QRINPSEYRDGIFDFNVGYIASAVLALVFLALGAFVQYGNGEAVQMAGGKYIGQLINM
                     YAVTIGGWSRPLVAFIAFACMYGTTITVVDGYARAIAEPVRLLRGKDKTGNAEFFAWN
                     IWVAGSGLAVIFWFDGVMANLLKFAMIAAFVSAPVFAWLNYRLVKGDEKHKLTSGMNA
                     LALAGLIYLTGFTVLFLLNLAGMFK"
     gene            3751..5262
                     /gene="lysS"
                     /locus_tag="ACFOAE_001640"
     CDS             3751..5262
                     /gene="lysS"
                     /locus_tag="ACFOAE_001640"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFC6885095.1"
                     /translation="MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDS
                     FAADLHAQYGEIGKEELDPQGIPVKVAGRMMLKRQMGKASFATIQDVSGQIQLYLNNK
                     GVSQEVLDDFNHWDLGDIVGAEGTLFKTNHGELTVRVSDIRLLSKSLRPLPDKHKGLS
                     DQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVNERYLEVETPMMHPIPGGAT
                     AKPFVTHHNALDIPLYLRIAPELYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTM
                     IEFYEAFSDYERMMQMAEDIIRNASRTVNGTANITYNGKEVDLESPFERLTILEAIKK
                     YNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDY
                     PVEVSPLARASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKSQVAQKDAGD
                     DEAMHYDADYIRAMEFGLPPTGGCGIGIDRLVMLLTDSQTIRDVILFPQMRPE"
     gene            complement(5339..5527)
                     /locus_tag="ACFOAE_001641"
                     /pseudo
     CDS             complement(5339..5527)
                     /locus_tag="ACFOAE_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311460.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5531..6409)
                     /locus_tag="ACFOAE_001642"
     CDS             complement(5531..6409)
                     /locus_tag="ACFOAE_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF723 domain-containing protein"
                     /protein_id="HFC6885096.1"
                     /translation="MARRSKTFEEAAAEVEERFGHRGIKLVEFEGTAKPCVINCPKHG
                     NQTCSRYSNMFIGSSWGCPSCGNEQAAKAGIATLRKNHIALEMLKQAVTGMTKQERIT
                     TQAYNEMTKSVAGSNSIVLNDVQGDTTINNHHTHTHNHSDADGKALSMRLTPRPLLSD
                     RQAAAFARTGKLTGSFDLFASVVAPSQYTFAVAMPDTSMSPVIEKGDLVVVEPRMRPA
                     DEDIVLIELSDKRLVVAHLVIDIAGRMLIYQTGRPSEAFDLPEGSTILGVVLEVKKRF
                     MSAAQARRRVDSDYRP"
     gene            complement(6439..7566)
                     /gene="fic"
                     /locus_tag="ACFOAE_001643"
     CDS             complement(6439..7566)
                     /gene="fic"
                     /locus_tag="ACFOAE_001643"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFC6885097.1"
                     /translation="MSNWKPDIPYNDLPPLPPKQDIESKTILKRCIAARASLARLKQA
                     AELIPNQAMLINTLPVMEARASSEIENIVTTTDKLFQSLQMDTERQDPATKEALQYRT
                     ALFAGYESLTSRPLCTQTAIMVCNAIKHPYEMAIRKTGGTALKGGNSGNVVYTPPEGE
                     ETIRGKLANWERFIHESGDLDPLIIMAAAHYQFEAIHPFTDGNGRTGRILNSLLLIEK
                     GLLDLPILYLSRYIIENRADYYRLLLGVTERQDWESWIIYILDGVADTADWTVSKIDA
                     IRRLFEQTRQHIRTHAQGIYTHELVNLLFEQPYTRIANLEAAGIAKRQTASKYLKELS
                     DIGVLQEIVIGRDKLFIHPRLMELLRGEGNSFTSFQSLVKA"
BASE COUNT         1714 a         1974 c         2200 g         1959 t
ORIGIN      
        1 cttgcggcaa gatgaaaacg gtgcgggatg ttttgggaaa ccaatgccgt ctgaagggct
       61 ttcagacggc attttttgcg ccgtgctgtt taacgcgcca gcggttcggt gcgtttgatc
      121 agccacgctt ttgccgcgcc ttcggtcagc ggctcgaggc ggcggcggac ttcggcgtgg
      181 tagcggttga cccagtcgat ttcgccgtcg gtcatgaggg cggtgtccat caggcgtgta
      241 tcgatggggc agagggtcag ggtttcaaaa cagaggaagc tgccgaattc ggtttcttga
      301 ggggtggcga cggcttggtt ggcggcaagg ttttcaatgc ggatgcccca ttttcccggg
      361 cggtagagtc cgggttcgat ggaggtaacc atgccttttt tcatggcggt ttcgggcgtg
      421 gcgggggcgg cgaaggcgat gcgctgcggg ccttcgtgga cgttgaggaa atagcctacg
      481 ccgtgtccgg tgccgtggcc gtagtcgcat tgcgcctgcc acaggggttt gcggcaaatc
      541 gcatcaatca gcggcgaggg gatgttttct gggaacacgg cttcggcaag cgcgatatgg
      601 gctttgagaa cgagggtgtt gtcgcgtttt tgttcggcgg tgggtgtgcc gacagggacg
      661 acgcgggtga tgtcggtcgt gccgcctttg tattgcgcgc cggagtcgat gagcaaaagc
      721 ccgttgccgc tgatggtgct gtggctttcg ggcgttgcgc tgtaatgcgg cagtgctccg
      781 ttggcgttga agcccgcgat ggtgtcgaaa ctcaatgaaa taaagcccgg acgtgcgctg
      841 cggtggcggt aaagcatggt gtccacgtcg atttcggtca ggctgccgcc gttgccgatg
      901 atgtcttcaa actcggcgaa gaaaccgcac aacgccgcgc cgtcgtgttc catcgcttcg
      961 cggatgcggg cgatgtcggc ttcggatttg caggatttga acagcgtgga cgggttgatg
     1021 ccttcgatca ggcgcacgct ttcgggcagg cgcacaaggg tactgacggc ggttttattc
     1081 ggctcgatga gcagcgtacc gccgatttgc gcgagtttgt cggcaacttg ggcgtaaggc
     1141 tcgaccgcga tgccggcggt ttgcagcgcg gcggcggctt cggcgttcag acggcattgt
     1201 tcggtaaaca ggacggcgtt gtctttgcca atcagcagga aggagacgaa aatgggattg
     1261 aaaggcacgt cgctgccgcg caggttggtc agccaggcga tgtcgtcaag cgaggaaacc
     1321 aagtggtaat ccgcgccttt ttccgccatc acggcgcgca cgcgggcgag tttttcggcg
     1381 gcggtttcgg agacgtaggc ggggtcgtgg atgaacacgg tttcggcggg gagggcggga
     1441 cggcttgtcc acacttggtc aagcagatcg tttgggtgtt cgatgcggat gtttttggcg
     1501 gtcagggatt gcgccaaagt gcgtttgccg gtgagcgaga ccatatcgga agggatgccg
     1561 acggcggcgt tttcgggcag gtttgccgcg agccattcgt tatacggcgg cacttgcccg
     1621 cttttttgca gttcgatgcc gctgcccgca agctgcttgg cggcttgttc ccaatagcgg
     1681 ctgtccaccc atacgcccgc ttcgtcggcg gtaacgacga atgtgccgac cgagccggta
     1741 aagcccgaca attcgcgccg cgcctgccaa tgttcgggca ggtattcgga caggtggggg
     1801 tcggcggaag ggatgacgag agcgtccaag ccttgcgcct tcatggcttc gcgcaatgcg
     1861 gacaggtaat tcgatacggt attcataaca gttcctccaa tcgggttttg cggcttcaga
     1921 cggcatggac ggaaatctga aatgccgtct gaaaaacata accatcttat caaatcgcca
     1981 gcctgctgca aaacggacgg gctgatcgga tggtgcgtgt ttgcgcgaaa aaagcgatgt
     2041 aaggttgttt gttgtaaaat tttaggcata agatatcgtt ttatgccttt ttttggaagt
     2101 aatatggaaa atatagtcaa gtttgagcat gaagttctaa tagtgtgtgt tggcaggtat
     2161 ttggattacg ttacaatacg cgctttcatc aaaatttccc taccgagcgg tatcctgttt
     2221 ttgaagacgg taggatttgg gtttgtttgg gggaatcccg cccaaattgg agcaatagat
     2281 agggctgtgt ccgaatatgc ggctctgtgt gttgaaacac ggttaaaaat acggaagact
     2341 ttatgtccga acaacatatt tcgacttgga aaagtaaaat caacgcattg ggaccgggga
     2401 ttatgatggc ttcggcggcg gtcggcggtt cgcacctgat tgcctcgacg caggcgggcg
     2461 cgctttacgg ctggcagatc gcgctcatca tcatcctgac caacctcttc aaatacccgt
     2521 ttttccgctt cagcgcgcat tacacgctgg acacgggcaa gagcctgatt gaaggttatg
     2581 ccgagaaaag ccgcgtttat ttgtgggtat tcctgatttt gtgcatcctc tccgccacga
     2641 ttaacgcggg cgcggtcgcc attgtaaccg ccgccatcgt caaaatggcg attccctcgc
     2701 tgatgtttga tgccggcacg gttgccgcct tgattatggc atcctgcctg attattttgg
     2761 tgagcggacg ttaccgcgct ttggatcgcg tttccaaaat catcatcgtt actttgagta
     2821 tcgccacgct tgctgccgcc ggcatcgcta tgtcgcgcgg tatgcagatg cagcccgatt
     2881 ttatcgagcc gacaccgtgg acgcttgccg gtttgggctt cctgatcgcg ctgatgggct
     2941 ggatgcccgc gccgattgaa atttccgcca tcaattcttt gtgggtaacc gaaaaacaac
     3001 gcatcaatcc ttccgaatac cgcgacggga tttttgattt caacgtcggt tatatcgcca
     3061 gtgcggtttt ggctttggtt ttccttgcac tgggtgcgtt tgtgcaatac ggcaacggcg
     3121 aagcagtgca gatggcgggc ggcaaatata tcgggcaatt gatcaatatg tacgccgtta
     3181 ccatcggcgg ctggtcgcgc ccgctggtgg cgtttatcgc gtttgcctgt atgtacggca
     3241 cgacgattac cgtcgtggac ggctatgccc gtgccattgc cgaacccgtg cgcctgctgc
     3301 gcggaaaaga caaaacgggc aacgccgaat tctttgcctg gaatatttgg gtggcgggca
     3361 gcggtttggc ggtgattttt tggtttgacg gcgtaatggc gaatctgctc aaatttgcga
     3421 tgattgctgc ttttgtgtcc gcccctgtgt ttgcctggct gaattaccgt ttggtcaaag
     3481 gtgatgaaaa acacaaactc acatcaggta tgaatgccct tgcattggca ggcttgattt
     3541 atctgaccgg ttttaccgtt ttgttcttat tgaatttggc gggaatgttc aaatgataac
     3601 gatgccgtct gaaaccgcaa accgctttca gacggcattg tcgcgtttat ggaaaaaaat
     3661 gccgacatcg cgtaaaatat gcgcaaattt tgtgattcgg tcaggtcgtc tgaaacagat
     3721 tgcgcctgat ttattttttc ggaaaaccct atgagcgaac aaaaccatcc gcaaaccgag
     3781 ccgcagttgg acgaaaacca aatcatcgcc ctgcgccgcg aaaaactgca caacatccgc
     3841 caacagcgca acgcctatcc caacgacttc aaacgcgaca gcttcgccgc cgatttgcac
     3901 gcccaatacg gcgaaatcgg caaagaagaa ctcgatccgc aaggcattcc cgtcaaagtg
     3961 gccggccgca tgatgctgaa gcgtcaaatg ggcaaggcga gctttgccac cattcaagac
     4021 gtgtccgggc aaatccagct ttatctgaac aacaaaggcg tgagccaaga agttttggac
     4081 gacttcaacc attgggattt gggcgacatc gtcggcgcgg aaggcacttt gttcaaaacc
     4141 aaccacggcg aactgaccgt acgcgtgtcc gacatccgcc tgctgtctaa atccttgcgt
     4201 ccgctgccgg acaaacacaa aggcttgagc gatcaggaaa ccaaataccg ccaacgctac
     4261 gtcgatttga ttgccaacga agaatcgcgc aataccttca tcaaacgcag ccaaatcatc
     4321 caatctgtgc gcaattttat ggtgaacgag cgttatctcg aagtcgaaac cccgatgatg
     4381 cacccgattc ccggcggcgc gacggcgaaa ccgttcgtga cccaccacaa tgccttggac
     4441 attccgctct acctgcgcat cgcccccgag ctgtatctga aacgcttggt tgtcggtggt
     4501 ttggaacgcg tgtttgaaat caaccgcagc ttccgcaacg aaggtatgtc tgtgcgccac
     4561 aatcccgaat tcaccatgat tgaattctac gaagccttct ccgactacga acgcatgatg
     4621 cagatggcgg aagacatcat cagaaacgca tcgcgcacag taaacggtac ggcaaacatc
     4681 acttacaacg gcaaagaagt cgatttggaa agcccgtttg aacgcctgac cattctcgaa
     4741 gccatcaaaa aatacaatcc gcactacacc gacgagcagt tgaacgatgc ggaatggctg
     4801 aaaaaagaaa tcgtcaaaca cggcgaaagc ctgccgccgt ccccgggcat cggcagcctg
     4861 caactcgcgc tgtttgaagg ttgcgccgaa ggcaaactgt ggaacccgac cttcatcgtc
     4921 gattatccgg tcgaagtttc cccgttggca cgtgcttccg ataccaaaca aggtctgacc
     4981 gaacgattcg agcttttcgt tgtcggccgc gaactggcaa acggctattc agaattgaat
     5041 gaccctgaag accaagccga acgcttcaaa tcgcaagtcg cacaaaaaga cgcgggcgac
     5101 gacgaagcca tgcattacga tgccgactac atccgcgcga tggaatttgg tttgccgccg
     5161 accggcggtt gcggcatcgg tatcgaccgc ttggtgatgt tgctgaccga ttcgcaaacc
     5221 atccgcgatg tgattctgtt tccgcagatg cgccccgagt agtcataaaa acagttgaaa
     5281 tggcaatgcc gtctgaaccc gattggattc agacggcatt ttgtatggcg gtacggattt
     5341 attcgctttc taactgaccg acccattcgg acaaggcagt caggcgttgt tcggatttcg
     5401 ccacgaacgg gttttcggta tcccacgcgt agcctgccaa aatcgaagaa agcatacggc
     5461 tgatttccgg gctgcggtcg ggcgcgtaca cgacgttttg gaagcggaaa tcataccaac
     5521 cgtccacaca tcaggggcgg taatccgaat caacacgcct tcttgcctgt gcggcggaca
     5581 taaaccgttt tttgacctcc agcaccacac ctaaaatcgt gctgccttcg ggcaggtcaa
     5641 aggcttcaga cggcctgccc gtctgataaa tcagcatcct gcccgcaata tcgataacaa
     5701 ggtgcgcgac gaccagccgc ttgtcggaca gttcaatcag cacgatgtcc tcgtccgcag
     5761 ggcgcatacg cggctcgacc accaccaaat cccctttttc gataaccggc gacatggacg
     5821 tgtcgggcat ggcaacggca aacgtgtact gcgagggggc gaccaccgaa gcaaacaagt
     5881 cgaaactgcc tgtgagtttg cctgtacggg cgaaagccgc cgcctgacgg tctgacaaca
     5941 gggggcgtgg tgtgagcctc atcgacagtg ctttgccgtc ggcatcgctg tggttgtgcg
     6001 tatgcgtatg atggttgttg atggtcgtat cgccttggac atcgttaagg actatgctgt
     6061 ttgaacctgc cacggatttg gtcatctcat tgtaggcttg cgtcgtgatg cgctcttgct
     6121 tggtcatacc tgttacagcc tgtttcagca tttctaacgc tatgtgattc ttcctaaggg
     6181 tcgctatacc ggcttttgca gcttgctcat taccacaaga ggggcaaccc cagctacttc
     6241 ctatgaacat attggagtac ctcgaacagg tttggtttcc atgtttaggg cagttgatta
     6301 cacacggctt ggctgtaccc tcaaactcga ccaacttaat gccacgatga ccgaaacgtt
     6361 cctcaacctc agcagcagct tcttcaaatg tttttgacct tcttgccata ttgacctccg
     6421 gattattgat tattttggct atgctttaac gagggattgg aatgaggtaa agctgttgcc
     6481 ctctccccgc aatagttcca ttaggcgcgg atgaatgaat agtttgtccc tgccgatgac
     6541 gatttcttgc agcacaccta tgtctgaaag ctctttcagg tacttagagg ccgtctgccg
     6601 tttggctatc cctgccgctt ctaggttggc aatgcgtgta tatggctgct caaacagaag
     6661 atttaccagt tcgtgcgtgt agattccttg tgcgtgtgtc cgtatgtgtt gccgtgtctg
     6721 ctcgaacagg cggcgtatcg catctatttt cgataccgtc caatcggcgg tatcggctac
     6781 gccgtctaag atgtagatta tccagctttc ccaatcctgc cgttcggtta cgcctaaaag
     6841 caggcggtaa tagtccgccc tgttttcgat gatgtagcgg ctcaaataca aaataggcaa
     6901 atccaaaagc cctttttcaa tcaatagcag gctgttcaat atgcgccccg tccgcccgtt
     6961 gccgtccgta aacggatgga tggcttcaaa ttggtaatgt gccgccgcca tgatgataag
     7021 cgggtctaaa tcgccgcttt cgtgaataaa ccgctcccaa tttgccagct tgccgcgtat
     7081 ggtttcttct ccttcgggcg gggtatagac aacatttccg ctgttgcctc cttttagggc
     7141 tgtgccgcct gttttgcgga tggccatttc gtaggggtgc ttgatggcgt tgcagaccat
     7201 gatggcggtt tgtgtgcata aagggcggct cgtcagtgat tcatagcctg caaacagggc
     7261 ggtgcggtat tgcagggctt ctttcgtggc agggtcttgc cgttccgtat ccatttgcag
     7321 ggattgaaac agcttgtccg ttgtggttac gatgttttca atttccgaac ttgcacgggc
     7381 ttccataaca ggaagggtgt taatcagcat ggcttgattc ggtatcaatt ctgccgcctg
     7441 ctttaaacgg gcaagggatg cacgggcggc tatacaacgt ttcaggatgg ttttgctttc
     7501 aatatcctgt tttggcggca ggggtggtaa atcgttatag ggaatatcgg gtttccagtt
     7561 gctcatattt aaaatttcgg aaaatttaaa gatgtttcca gtatatattt acgccgtgta
     7621 tatatcaagg atatatgttt aaaaatttgg cttttgtaaa tatatgggcg gtaaaaccgc
     7681 attattttat gttgttacct attttacacc ttgtctgcac acgatttcca aacaacctaa
     7741 aaagaaacct gccgaaaggc aggtttaaag aggtcatttt aaatgtgaac taaagtttac
     7801 accctcggag ggtatcgcgt atatcagacg tacttaatat acactat
//
LOCUS       DAXIDM010000093         7674 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000093 DAXIDM010000000
VERSION     DAXIDM010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7674
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.093"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(9..425)
                     /gene="dksA"
                     /locus_tag="ACFOAE_001644"
     CDS             complement(9..425)
                     /gene="dksA"
                     /locus_tag="ACFOAE_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0019899 - enzyme binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HFC6885098.1"
                     /translation="MAKLTEQDILNWSGPEDDYMNDDHLAFFRELLVKMQDELIENAS
                     ATTGHLQEHESAPDPADRATQEEEYALELRTRDRERKLLSKIQATIRNIDEGDYGFCA
                     DTGEPIGLKRLLARPTATLSVESQERRERMKKQFAD"
     gene            complement(572..1381)
                     /gene="proC"
                     /locus_tag="ACFOAE_001645"
     CDS             complement(572..1381)
                     /gene="proC"
                     /locus_tag="ACFOAE_001645"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFC6885099.1"
                     /translation="MNRVEIMNVYFLGGGNMAAAVAGGLVKQGGYRIYIANRGAEKRE
                     RLEKELGVETSATLPELHSDDVLILAVKPQDMEAACKNICTNGALVLSVAAGLSVGTL
                     SRYLGGSRRIVRVMPNTPGKIGLGVSGMYAEAEVSETDRRIADRIMKSVGLTVWLEDE
                     AQMHSITGISGSGPAYVFYLLDALQNAAIRQGFDMAEARALSLATFKGAVTLAEQTGE
                     DFEKLQKNVTSKGGTTHEAVEAFRRHRVAEAISEGVCACVRRSQEMERQYQ"
     gene            complement(1412..1820)
                     /locus_tag="ACFOAE_001646"
                     /pseudo
     CDS             complement(1412..1820)
                     /locus_tag="ACFOAE_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815987.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            complement(1820..2506)
                     /locus_tag="ACFOAE_001647"
     CDS             complement(1820..2506)
                     /locus_tag="ACFOAE_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFC6885100.1"
                     /translation="MTVLQERYREVSDRIGKLVLQAGRKPHSVSLIAVGKTFPSDGIR
                     EVYAAGQRDFGENYIQEWYGKTEELADLTDIVWHVIGDVQSNKTKFVAERAHWVHTVC
                     RLKTAVRLSGQRPSSMPPLQVCIEVNIAGEAVKHGVAPEEAVALAVEVAKLPNIVVRG
                     LMCVAKANSSETELKVQFQTMRKLLADLNAAGVKADVLSMGMSDDMPAAIECGATHVR
                     IGSAIFGKRG"
     gene            2626..3669
                     /gene="pilT"
                     /locus_tag="ACFOAE_001648"
     CDS             2626..3669
                     /gene="pilT"
                     /locus_tag="ACFOAE_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HFC6885101.1"
                     /translation="MQITDLLAFGAKNKASDLHLSSGISPMIRVHGDMRRINLPEMSA
                     EEVGNMVTSVMNDHQRKIYQQNLEVDFSFELPNVARFRVNAFNIGRGPAAVFRTIPST
                     VLSLEELKAPSIFQKIAESPRGMVLVTGPTGSGKSTTLAAMINYINETQPAHILTIED
                     PIEFVHQSKKSLINQRELHQHTLSFANALRSALREDPDVILVGEMRDPETIGLALTAA
                     ETGHLVFGTLHTTGAAKTVDRIVDVFPAGEKEMVRSMLSESLTAVISQNLLKTHDGNG
                     RVASHEILIANPAVRNLIRENKITQINSVLQTGQASGMQTMDQSLQSLVRQGLIAPEV
                     ARRRAQNSESMSF"
     gene            3832..5058
                     /locus_tag="ACFOAE_001649"
     CDS             3832..5058
                     /locus_tag="ACFOAE_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="HFC6885102.1"
                     /translation="MNTDNLHDILDEMVQVYSQKKQSRSETPAEIGAHFHPLLDRLCE
                     TAEAQNASDILISKGFPPSLKINSALTPQPQKALTGEETAAIAASTMNAEQSEIFRRD
                     GEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMQELGLPEKLKDLAVAPRG
                     LLIIVGPTGSGKSTTMATMLEHRNKTLPSHIVTIEDPIEFIYKPRRCIFTQREIGVDT
                     INWQTAVQNAMRQSPDVVCIGEVRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERI
                     LNFYPKEQHNQILIDIALNLTGIICQRLALKQDKTGRTAVVDLLINTPAIQDFILKGD
                     LMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGK
                     TPELLYDRVNGLNLIS"
     gene            5344..7494
                     /gene="yccS"
                     /locus_tag="ACFOAE_001650"
     CDS             5344..7494
                     /gene="yccS"
                     /locus_tag="ACFOAE_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YccS family putative transporter"
                     /protein_id="HFC6885103.1"
                     /translation="MKTPLLKPLLITSLPVFASVFTAASIVWQLGEPKLAMPFVLGII
                     AGGLVDLDNRLTGRLKNIIATVALFTLSSLTAQSTLGTGLPFILAMTLMTFGFTILGA
                     VGLKYRTFAFGALAVATYTTLTYTPETYWLTNPFMILCGTVLYSTAIILFQIILPHRP
                     VQESVANAYDALGGYLEAKADFFDPDEAEWIGNRHIDLAMSNTGVITAFNQCRSALFY
                     RLRGKHRHPRTAKMLRYYFAAQDIHERISSAHVDYQEMSEKFKNTDIIFRIHRLLEMQ
                     GQACRNTAQALRASKDYVYSKRLGRAIEGCRQSLRLLSDSNDSPDIRHLRRLLDNLGS
                     VDQQFRQLQHNGLQAENDRMGDTRIAALETGSLKNTWQAIRPQLNLESGVFRHAVRLS
                     LVVAAACTIVEALNLNLGYWILLTALFVCQPNYTATKSRVRQRIAGTVLGVIVGSLVP
                     YFTPSVETKLWIVIASTTLFFMTRTYKYSFSTFFITIQALTSLSLAGLDVYAAMPVRI
                     IDTIIGASLAWAAVSYLWPDWKYLTLERTAALAVCSNGAYLEKIAERLKSGETADDVE
                     YRATRRRAHEHTAALSSTLSDMSSEPAKFADSLQPGFTLLKTGYALTGYISALGAYRS
                     EMHEECSPDFTAQFHLAAEHTAHIFQHLPETEPDDFQTALDTLRGELDTLRTHSSGTQ
                     SHILLQQLQLIARQLEPYYRAYRQIPHRQPQNAA"
BASE COUNT         1886 a         2562 c         1673 g         1553 t
ORIGIN      
        1 tgccgccatc agtcggcaaa ctgttttttc atcctctctc ggcgttcttg ggactcaaca
       61 gataaagtgg ctgtcgggcg tgccagcagc cgcttcagac cgataggctc tcccgtatcg
      121 gcacagaatc cataatcccc ttcatcaata ttgcggatgg tcgcctgtat tttactgaga
      181 agttttcgtt cccgatcgcg ggtacggagt tccaatgcgt actcttcttc ctgtgtggca
      241 cggtcggcag gatcgggggc tgattcgtgt tcttggagat gccctgtcgt agcggaagca
      301 ttttcgatga gttcgtcttg catttttacc agcaattcgc ggaaaaaagc caaatggtcg
      361 tcattcatat aatcgtcttc cggcccgctc caattcaaaa tatcttgttc tgtcagcttt
      421 gccataatgt atatcctctc ggttcaccga aaaaaacaaa gcaccacaaa gtggctttat
      481 tcctttgatt tttataaggc ttattgccta aggcgttttt gaaaacgcgc atcataacac
      541 gttttggatt ggttttttta ttttctttac attattgata ttgccgttcc atttcctgcg
      601 aacggcgcac acaggcacaa acgccctcgc ttatggcttc ggcgacacga tgccgcctga
      661 aagcttccac ggcttcgtgg gttgtcccgc cttttgacgt tacatttttt tgaagcttct
      721 cgaaatcttc acccgtctgc tcggcaaggg taaccgctcc tttaaacgtt gccagactga
      781 gcgcgcgtgc ttctgccata tcaaaccctt gtcggatggc ggcattttgc aatgcgtcca
      841 gcagataaaa cacataagcc ggtccgctgc cgctgatacc ggtaatgctg tgcatttgcg
      901 cttcatcttc caaccaaacg gtcaaaccga ctgatttcat gattcgatcg gcaatcctgc
      961 ggtctgtttc cgatacttcc gcttcggcat acataccgga tacgcccagt cctattttcc
     1021 cgggcgtatt cggcataacc cggacaatgc ggcggcttcc cccgaggtaa cggctgagcg
     1081 taccgactga caatccggct gcgacagaaa gcaccaatgc gccgttggtg cagatatttt
     1141 tgcacgcggc ttccatatcc tgcggtttga cggcaaggat taaaacatcg tcggaatgaa
     1201 gctccggcag ggttgccgaa gtttcgaccc ccaactcttt ttccaaacgt tcgcgttttt
     1261 ccgcaccccg attggctata tagatgcggt aaccgccttg tttgaccaat ccgcccgcaa
     1321 cggcagccgc catattgccg ccgccgagaa aataaacatt cattatttct accctattca
     1381 aaattacctg actaaattca ttcccaattt tttaccatcg gacgcgctcg gacagaccgt
     1441 tgcgccgcaa cccctgcttt tccaagcagt caaatcctcc ctgtttgaac gtctcaatca
     1501 aaggtttgcc gtcacgcgta cgccaatcca gcccgcaggc ttcaaacttc cctattttcc
     1561 tgtaaaagta agattgttgt gcggattcat attcgtttgc cctgacggaa cgattgccgt
     1621 ctgaaagcgg tatctcgtag tcctctaaag acggcggact ctcgccgcca atatcccaaa
     1681 aatcgatggc agccggtttt ctcggcttac accagccgga cagggacgaa cactcaatac
     1741 caacccgcca accggcagcc tgcaaccgta aatgcaagca acgcagccat tgccgtatat
     1801 tttattgccc gaatttccat cagccccttt tcccgaaaat cgcgctgccg atacggacgt
     1861 gtgtcgcacc gcactcaatg gcggcaggca tatcgtccga catccccata gacagcacgt
     1921 ctgccttaac gccagccgca ttgaggtcgg caagcagttt ccgcatcgtt tgaaattgca
     1981 ccttcaactc cgtttcactg ctgttggctt tggcaacaca catcagtccg cgtacgacga
     2041 tattcggcag cttcgccact tccacagcaa gcgcgactgc ttcttcgggc gcgacaccgt
     2101 gcttcaccgc ctcgcccgca atgttcacct caatacacac ctgcaaaggc ggcattgagg
     2161 aaggacgttg cccgctcagc cggacagcgg tctttagacg gcatacggta tgcacccaat
     2221 gcgcgcgttc ggcgacaaac ttggttttgt tggactgcac atcgccgatg acgtgccaca
     2281 cgatgtcggt caaatccgcc aactcttccg ttttgccgta ccactcctga atatagttct
     2341 cgccgaaatc acgctgtccg gcggcgtaaa cttcgcggat gccgtctgaa gggaaagtct
     2401 taccgacggc aatcaggctg acggaatgcg gcttccttcc cgcctgcaga accaattttc
     2461 caatacggtc ggacacctcc cgataacgtt cttgcaacac cgtcatagat tatcccctaa
     2521 ttaaaaatga ttaaacagtt gaaacccctc cagtcagggc ggtacaatca aggttgttag
     2581 aaccattcca accaatcgaa acattatact aaacagagcc gcattatgca gattaccgac
     2641 ttactcgcct tcggcgctaa aaacaaagca tccgaccttc acctgagttc gggcatatcc
     2701 cctatgattc gggttcacgg cgatatgcgg cgcatcaacc ttcccgaaat gagcgcggaa
     2761 gaggtcggta atatggtaac ttcggtgatg aacgaccacc agcggaaaat ctaccagcaa
     2821 aacttggaag tcgacttctc gttcgaactg cccaacgtcg cccgattccg cgtcaacgcc
     2881 ttcaacatcg gccgcggtcc cgccgccgta ttccgcacca ttcccagcac cgtcttatcg
     2941 ctggaagaat tgaaagcccc gagcattttc caaaaaatcg cagaatcgcc gcgcggcatg
     3001 gttttggtta ccggccctac cggttcgggc aaatcgacca cgcttgccgc aatgatcaac
     3061 tacatcaacg aaacccagcc ggcacacatc ctgaccatcg aagacccgat cgaattcgtc
     3121 caccaaagca aaaaatccct gattaaccag cgcgagctgc accagcacac cctcagcttc
     3181 gccaacgcgc tgcgttccgc attgcgcgaa gaccccgacg ttatccttgt tggcgagatg
     3241 cgcgaccccg aaaccatcgg cttggcactg accgccgccg aaaccggaca cttggttttc
     3301 ggcacgctgc acacgaccgg cgcagcaaaa accgtcgacc gtatcgtgga cgtattccca
     3361 gcgggagaaa aagaaatggt gcgctctatg ctgtccgaat cgctgaccgc cgtcatctcc
     3421 caaaacctgc tgaaaacgca cgacggcaac ggccgtgtcg cctcgcacga aatcctgatt
     3481 gccaaccccg ccgtccgcaa cctcatccgc gaaaacaaaa tcacgcagat taactccgtc
     3541 ctgcaaaccg ggcaggcgag cggtatgcag acgatggacc aatcgctgca atcgctggtg
     3601 cgccaagggc tgatcgcacc ggaagtcgca cgcagacgcg cgcaaaacag cgaaagtatg
     3661 agtttctgac acacaaccgc cttccggcca taccggcggg aaaacaaggc gcaaacacgc
     3721 ggggcgggac gcagcatccc gcccggctac ctttccgaac aggaagcgtc cgccttcctg
     3781 ttgaaacctg ccgccgcaaa ctgcaaggct taaaccgaaa agaagctaac gatgaatacc
     3841 gataacctgc acgacatctt ggacgaaatg gttcaagtgt attctcaaaa aaaacaaagc
     3901 cgatccgaaa ccccggccga aatcggcgca cacttccacc cgctgctcga ccgcctgtgc
     3961 gaaaccgcag aagcacaaaa cgcgtccgac atccttatca gcaaaggatt cccgccctcg
     4021 ttgaaaatca acagcgcatt aaccccgcag ccgcaaaagg cgctgacggg cgaggaaacc
     4081 gccgccatcg ccgcatcgac gatgaacgcc gaacaatcgg aaatattccg gcgcgacggc
     4141 gaaatcaact actccgtcca gtcgcgcagc ggcacgcgct accgcgccaa cgcctaccac
     4201 agccaaggca gcgcaggttt ggttttgcgg cgcatcaacc acgtcatccc gcaaatgcag
     4261 gaattgggcc tgcccgaaaa actcaaagac ctcgccgtcg caccgcgcgg gctgctgatt
     4321 atcgtcgggc ctaccggttc gggcaaatcc accacgatgg cgactatgct cgaacaccgc
     4381 aacaaaaccc tgcccagcca tatcgttacc atcgaagacc cgattgagtt tatctacaaa
     4441 ccgcgccgct gcatctttac ccagcgcgaa atcggcgtcg acaccataaa ctggcagacg
     4501 gcggtacaaa acgctatgcg ccagtccccc gacgtggtct gcatcggcga agtccgcagc
     4561 agggaaagta tggaatacgc gatgcagctc gcccaaaccg gccacctgtg catttttacg
     4621 ctccacgcca acaccgcgcc gcagtcgctc gaacgcatac tcaacttcta ccccaaagaa
     4681 cagcacaacc aaatactgat cgacatcgcc ctcaacctga ccggcatcat ctgccaacgc
     4741 ctcgccctca aacaagacaa aacgggcagg acggcggttg tcgacttgct catcaacacg
     4801 cccgccatcc aagacttcat cctgaagggc gacctgatga acatcagtaa aatcatggaa
     4861 accgccaaaa ccgacggaat gcagacgatg gatcaaaacc ttttcgaact gtaccgtcac
     4921 ggcatcatca gttacgaaga agccctgcgc cagtccgttt ccgccaacaa cctgcgattg
     4981 cacatccaac tgcacaaaga aggcaaaacg cccgaactcc tttacgacag ggtcaacggt
     5041 ctcaacctca tttcctgatc cgcaaaaccc aatgccgtct gaaaaccgca tccccgtttt
     5101 cagacggcat gattttatcc gccccattca tgtgctacac tttatagtgg attaaattta
     5161 tagtggatta acaaaaatca ggacaaggcg acgaagccgc agacagcaca aatagtacgg
     5221 aaccgattca cttggtgctt cagcacctta gagaatcgtt ctctttcagc taaggcgagg
     5281 caacgccgta ctggtttttg ttaatccact atattcactt cataacaata aaccggtaaa
     5341 accatgaaaa ccccactcct caagcctctg ctcattacct cgcttcccgt tttcgccagt
     5401 gtttttaccg ccgcctccat cgtctggcag ctaggcgaac ccaagctcgc catgcccttc
     5461 gtactcggca tcatcgccgg cggccttgtc gatttggaca accgcctgac cggacggctg
     5521 aaaaacatca tcgccaccgt cgccctgttt accctctcct cgctcacggc acaaagcacc
     5581 ctcggcacag ggctgccctt catcctcgcc atgaccctga tgaccttcgg ctttaccatt
     5641 ttaggcgcgg tcgggctgaa ataccgcacc ttcgccttcg gcgcactcgc cgtcgccacc
     5701 tacaccacac ttacctacac ccccgaaacc tactggctga ccaacccctt catgatttta
     5761 tgcggcaccg tactgtacag caccgccatc atcctgttcc aaatcatcct gccccaccgc
     5821 cccgtccaag aaagcgtcgc caacgcctac gacgcactcg gcggctacct cgaagctaaa
     5881 gccgactttt tcgatcccga cgaagccgaa tggataggca accgccacat cgacctcgcc
     5941 atgagcaaca ccggcgtcat caccgccttc aaccaatgcc gttccgccct gttttaccgc
     6001 cttcgcggca aacaccgcca cccgcgcacc gccaaaatgc tgcgttacta ctttgccgcc
     6061 caagacatac acgaacgcat cagctccgcc cacgtcgatt atcaggaaat gtccgaaaaa
     6121 ttcaaaaaca ccgacatcat cttccgcatc caccgcctgc tcgaaatgca gggacaagcc
     6181 tgccgcaaca ccgcccaagc cctgcgcgca agcaaagact acgtttacag caaacgcctc
     6241 ggccgcgcca tcgaaggctg ccgccaatcg ctgcgcctcc tttcagacag caacgacagt
     6301 cccgacatcc gccacctgcg ccgccttctc gacaacctcg gcagcgtcga ccagcagttc
     6361 cgccaactcc agcacaacgg cctgcaggca gaaaacgacc gcatgggcga cacccgcatc
     6421 gccgccctcg aaaccggcag cctcaaaaac acctggcagg caatccgtcc tcagctaaac
     6481 ctcgaatcag gcgtattccg ccatgccgtc cgcctgtccc tcgtcgttgc cgccgcctgc
     6541 accatcgtcg aagccctcaa cctcaacctc ggctactgga tactactgac cgcccttttc
     6601 gtctgccaac ccaactacac cgccaccaaa agccgcgtcc gccagcgcat cgccggcacc
     6661 gtactcggcg taatcgtcgg ctcgctcgtc ccctacttta ccccctccgt cgaaaccaag
     6721 ctttggatcg tcatcgccag taccaccctc tttttcatga cccgcaccta caaatacagc
     6781 ttctcgacat ttttcatcac cattcaagcc ctgaccagcc tctccctcgc agggttggac
     6841 gtatacgccg ccatgcccgt acgcatcatc gacaccatta tcggcgcatc ccttgcctgg
     6901 gcggcagtca gctacctatg gccagactgg aaatacctca cgctcgaacg caccgccgcc
     6961 cttgccgtat gcagcaacgg cgcctatctc gaaaaaatcg ccgaacgcct caaaagcggc
     7021 gaaacggccg acgacgtcga ataccgcgcc acccgccgcc gcgcccacga acacaccgcc
     7081 gccctcagca gcaccctttc cgacatgagc agcgaacccg caaaattcgc cgacagcctg
     7141 caacccggct ttaccctgct caaaaccggc tacgccctga ccggctacat ctccgccctc
     7201 ggcgcatacc gcagcgaaat gcacgaagaa tgcagccccg actttaccgc acagttccac
     7261 ctcgccgccg aacacaccgc ccacatcttc caacacctgc ccgaaaccga acccgacgac
     7321 tttcagacag cactggatac actgcgcggc gaactcgaca ccctccgcac ccacagcagc
     7381 ggaacacaaa gccacatcct cctccaacag ctccaactca tcgcccggca gctcgaaccc
     7441 tactaccgcg cctaccgaca aattccgcac aggcagcccc aaaacgcagc ctgaaaaagt
     7501 ttcggcattt tgtaagagag ggcagattgt cagacaggtt gcaagatagt ggataaagct
     7561 ttgcgcaggg taaatgcgta gcaactgaac cgtcattccc acgaatctac attccgtcat
     7621 tcccacgaaa acagaaaacc aaaaacagaa acctaaaatc ccgtcattcc cacg
//
LOCUS       DAXIDM010000094         7264 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000094 DAXIDM010000000
VERSION     DAXIDM010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7264
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.094"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            200..1278
                     /gene="hupA"
                     /locus_tag="ACFOAE_001651"
                     /pseudo
     CDS             200..1278
                     /gene="hupA"
                     /locus_tag="ACFOAE_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236200.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemoglobin-haptoglobin-utilization protein HupA"
     gene            1306..3732
                     /gene="hupB"
                     /locus_tag="ACFOAE_001652"
     CDS             1306..3732
                     /gene="hupB"
                     /locus_tag="ACFOAE_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemoglobin-haptoglobin-utilization protein HupB"
                     /protein_id="HFC6885104.1"
                     /translation="MSIPFKPVLAAAAIAQAFPAFAADPAPQSAQTLNEITVTGTHKT
                     QKLGEEKIRRKTLDKLLVNDEHDLVRYDPGISVVEGGRAGSNGFTIRGVDKDRVAINV
                     DGLAQAESRSSEAFQELFGAYGNFNANRNTSEPENFSEVTITKGADSLKSGSGALGGA
                     VNYQTKSASDYVSEDKPYHLGIKGGSVGKNSQKFSSITAAGRLFGLDALLVYTRRFGK
                     ETKNRSTEGDVKIENKGYVFSPTQSFSKYQTYVATGVARSQPDPQEWVNKSTLFKLGY
                     NFNDRNRIGWIFEDSRTDRFTNELSNLWTGTIYSPATGDYRHRQDVSYRRRSGVEYKN
                     ELEHGPWDSLKLRYDKQRIDMNTWTWDIPKNYDLRGINSEVYHSFRHIRQNTAQWTAD
                     FEKQLDFSKAVWAAQYGLGGGRGDNANSDYSYFVKLYDPKIFTSNQAKITMLIESRSK
                     YKFAYWNNAFHLGGNDRFRLNAGIRYDKNSSSAKDDPKYTTAIRGQIPHLGSERAHAG
                     FSYGTGFDWRFTKHLHLLAKYSTGFRAPTSDETWLLFPHPDFYLKANPELKAEKAKNW
                     ELGLAGSGKAGNFKLSGFKTKYRDFIELTYMGVSSDDKNNPRYAPLSDDTALVSSPVW
                     QNQNRSSAWVKGLEFNGTWNLDSIGLPKGLHTGLNVSYIKGKATQNNGKETPINALSP
                     WTAVYSLGYDAPSKRWGINAYATRTAAKKPSDTVHSNDDLNNPWPYAKHSKAYTLFDL
                     SAYLNIGKQVTLRAAAYNITNKQYYTWESLRSIREFGTVNRVDNKTHAGIQRFTSPGR
                     SYNFTIEAKF"
     gene            3740..3952
                     /locus_tag="ACFOAE_001653"
     CDS             3740..3952
                     /locus_tag="ACFOAE_001653"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885105.1"
                     /translation="MCQCRLKPDDLGFRRHFLRSHRRPLSGLYQAQSRNSPSFPQLSV
                     IPATLRHSRNSPSFPQLSVITTEVGI"
     gene            complement(4377..6011)
                     /gene="groL"
                     /locus_tag="ACFOAE_001654"
     CDS             complement(4377..6011)
                     /gene="groL"
                     /locus_tag="ACFOAE_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271863.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFC6885106.1"
                     /translation="MAAKDVQFGNEVRQKMVNGVNILANAVRVTLGPKGRNVVVDRAF
                     GGPHITKDGVTVAKEIELKDKFENMGAQMVKEVASKTNDVAGDGTTTATVLAQSIVAE
                     GMKYVTAGMNPTDLKRGIDKAVAALVEELQNIAKPCDTSKEIAQVGSISANSDEQVGA
                     IIAEAMEKVGKEGVITVEDGKSLENELDVVEGMQFDRGYLSPYFINDAEKQIAALDNP
                     FVLLFDKKISNIRDLLPVLEQVAKASRPLLIIAEDVEGEALATLVVNNIRGILKTVAV
                     KAPGFGDRRKAMLQDIAILTGGTVISEEVGLSLEKATLEDLGQAKRIEIGKENTTIID
                     GFGDAAQIEARVAEIRQQIETATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KDRVEDALHATRAAVEEGVVAGGGVALLRARAALENLHTGNADQDAGVQIVLRAVESP
                     LRQIVANAGGEPSVVVNKVLEGKGNYGYNAGSGEYGDMIEMGVLDPAKVTRSALQHAA
                     SIAGLMLTTDCMIAEIPEEKPAMPDMGGMGGMGGMM"
     gene            complement(6105..6392)
                     /locus_tag="ACFOAE_001655"
     CDS             complement(6105..6392)
                     /locus_tag="ACFOAE_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019270883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFC6885107.1"
                     /translation="MTIRPLHDRVVVKRLEAEEKTASGIVLPGAAAEKPDMGEVIAVG
                     AGKIGKDGARRPLDVKVGDKIIFGKYSGQTVKADGEELLVMREEDIFGIVE"
     gene            6620..>7264
                     /locus_tag="ACFOAE_001656"
     CDS             6620..>7264
                     /locus_tag="ACFOAE_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6885108.1"
                     /translation="MKITHCKLKKKVQKELLRFFVLEVTARSAADILGIHPNSAALFY
                     RKIRTVINHHLALAADEVFEGSVEPDESDFGGRRKGRRGRGAAGKVVVFGILKRNGRV
                     YTVVVNNAKSETLLPVIKKKIMPDSIVYTDSLSSYDKLDVSGFIHHRINHSKEFADRQ
                     NHINGIENFWNQSKRVLRKYNGIDRKSFPLFLKECEFRFNFGTPSRQLKILQDWC"
BASE COUNT         1801 a         2100 c         1744 g         1619 t
ORIGIN      
        1 tagtacggaa ccgattcact tggtgcttca gcaccttaga gaatcgttct ctttgagcta
       61 aggcgaggca acgccgtact ggtttttgtt aatccactat accgattttt gcaccgaccc
      121 acaaaaccag ttgacatcat ataacattta aactgataat caaaactatt attaacacat
      181 catcaagatt gagtatgcga tgaaatacaa agccctgtcc ttactgccgc ttgccgctgc
      241 ccttgccgcc tgtgccgggg gggggtagcc gaaccgcacg tccccgtgtc catccccacc
      301 gccacgccgc tgcccaaagg cgaggtaacg ttatcaagcg ataacggcaa tatcgaaaac
      361 atcaacaccg ccaacactga aacacatccg ccgcgccgca ccagacgctc cctctatgcc
      421 tccccgcaaa acacatcctc cggtatttcc attcagcagc gggaagtaga aaaaatctat
      481 ttcggtgtta aatcaccaga aaaatcattc atcttccaaa cacccggcgg cgcgcaatac
      541 accctttcat cctacgccga ccccataacc gtcagctact cctcccccga tttcaaaatt
      601 cccgaccgcc acgcagggca gcggcttgca gacggcagcc gcatctttat ctgctgcagc
      661 gactccgggg caaccagaga agcggaaatt accaaacaag attatatgaa attcggggca
      721 tggataggtc ccaacggcga aatcgacctc ttcgccggcg gcttccccgt cggcaaaaca
      781 ccgacatcaa gcagttatta cggcagcagc acgcccgaaa cccaaggcaa aggcaaaatc
      841 acttatcagg tttggggcat ccgcgtcaaa gacgggcaat ttgttacctc ctcttatacg
      901 ccgcccaaag gcagctcttt taccggctac accaacaccc ccgtcctttc ctttatcacc
      961 gccaatttca acagcaacaa actggcaggc gaaatccgcg gcaacagcga ttacggaccg
     1021 agtgtgaaaa ttgaaaacgc aacgatcagc ggtccgagct tttccggcaa tgccacctcc
     1081 ggcggcaaaa ccggcaactt ggaaggcaag ttttttggaa aattcaacgg cagctacggc
     1141 aacactgaaa ccagcatagg cggcaaaatc acttttaaag acgaccgctc cctcgatacc
     1201 gtattcggcg gtgtgagtta tgtaaaaaaa cttgatgaaa ccgccaatcg agataccgaa
     1261 caccttacta aacaataaac catctcatcc ctacaaaggt ttcttatgtc catccccttc
     1321 aaacccgtat tggctgccgc cgccatcgcc caagcgtttc ccgcctttgc ggcagacccc
     1381 gcgccgcagt ccgcccaaac gctgaacgaa atcaccgtta ccggcacgca caaaacccaa
     1441 aaactcggcg aagaaaaaat ccgccgcaaa accttagaca agctcttggt caacgacgaa
     1501 cacgacctgg tgcgctacga ccccggcatt tccgtcgtcg aaggcggcag ggcgggttct
     1561 aacggcttta ccatacgcgg cgtggacaaa gaccgcgtcg ccatcaacgt tgacgggctg
     1621 gcgcaggcgg aaagccgctc ttccgaagcc ttccaagaat tgttcggcgc gtacggcaac
     1681 ttcaacgcca accgcaacac ttccgagccg gaaaactttt ccgaagtaac catcaccaaa
     1741 ggcgcggact cgctcaaatc cggcagcggc gcattgggcg gcgcagtcaa ttaccaaacc
     1801 aaatccgcaa gcgattatgt ttccgaagac aagccctacc atttggggat aaagggcggc
     1861 agcgtcggca aaaacagcca aaagttcagc agcatcaccg ccgccggcag gctctttggt
     1921 ttggatgcct tattggttta tacccgccgc ttcggcaaag aaaccaaaaa ccgctcgacc
     1981 gagggcgatg tcaaaattga aaacaaggga tatgttttca gcccaaccca atcattcagc
     2041 aagtaccaga cctacgtagc cacaggggtt gcgcgctccc aacccgaccc gcaagaatgg
     2101 gtaaacaaaa gcaccttgtt caagctgggc tacaatttca acgaccgcaa ccgcatcggc
     2161 tggatttttg aagactcccg caccgaccgt tttaccaacg agctgtctaa tttgtggacg
     2221 ggtacaattt actctcccgc aacgggcgac taccgccacc gccaagacgt gagctaccgc
     2281 cgccgctccg gcgtcgaata caaaaacgaa ttggaacacg gcccgtggga cagcctcaag
     2341 ctgcgctacg acaagcagcg catcgatatg aacacttgga cttgggacat cccgaaaaat
     2401 tacgatttgc gcggcatcaa cagtgaagtt taccattcgt tccggcatat ccgccaaaac
     2461 accgcgcaat ggactgccga ttttgaaaaa caactcgact tttccaaagc cgtttgggcg
     2521 gcgcaatacg gcttgggcgg cggcagaggg gacaatgcca actcggatta cagctatttc
     2581 gtaaaactgt acgaccccaa aatcttcact tccaaccaag ccaaaatcac gatgctgatc
     2641 gaaagccggt cgaaatataa atttgcctat tggaacaatg cgtttcactt gggcggcaac
     2701 gaccgcttcc gcctgaatgc gggcatacgc tacgacaaaa acagcagcag cgcgaaagac
     2761 gatccgaaat acaccaccgc catccggggg cagattcccc atttgggttc ggaacgcgcg
     2821 cacgcgggct tcagctacgg cacggggttc gactggcggt ttaccaagca tctgcacttg
     2881 ttggcaaaat acagcaccgg cttccgcgca ccgacttcgg acgaaacctg gctgctgttc
     2941 ccacaccccg atttctacct gaaagccaac cccgaactga aagcggaaaa agccaaaaac
     3001 tgggaattgg gcctggcggg cagcggcaag gcgggcaact tcaagctctc gggcttcaaa
     3061 accaaatacc gcgactttat cgaattgacg tatatgggcg tttcgtcaga cgataaaaac
     3121 aaccccagat acgccccgct ttcagacgac accgcattgg tcagctcgcc cgtttggcaa
     3181 aaccaaaacc gctcctcagc atgggtaaaa ggtttggaat ttaacggtac atggaatctc
     3241 gacagtatcg gtttgcccaa agggctgcac accggcctca acgtcagcta catcaagggc
     3301 aaggcaacgc aaaacaacgg caaagaaacg cccatcaacg cgctttcgcc gtggacggcg
     3361 gtttacagcc tgggctatga cgcgccttcc aaacgctggg gcatcaacgc ctacgccacg
     3421 cgcaccgccg ccaaaaagcc gtccgacacc gtacacagca acgacgactt gaacaacccg
     3481 tggccttatg ccaaacacag caaggcctat acgctgttcg acctttccgc ctacctcaac
     3541 atcggcaaac aggtaacgct ccgcgccgcc gcgtacaaca ttaccaacaa gcagtactac
     3601 acttgggaat ctttacgcag catccgcgag ttcggcacgg tcaaccgcgt tgacaacaaa
     3661 acccacgccg gcatccaacg ctttacctcg ccgggcagga gctacaattt caccatcgaa
     3721 gcgaagttct aagctcctga tgtgccaatg ccgtctgaaa cccgatgatt tgggtttcag
     3781 acggcatttt ttacggtcgc accgccgccc cctttcaggc ttgtaccaag cccaatcccg
     3841 caactctccg tcattcccgc aactctccgt cattcccgca actctccgtc attcccgcaa
     3901 ctctccgtca ttcccgcaac tctccgtcat taccacggaa gtgggaatct agaaacgcaa
     3961 agctgcaaga atttatcgga aatgactgaa actcaacgaa cctggattcc cgcctgcgcg
     4021 ggaatgacga agccatccgc acggaaacct gcaccacgtc attcccacga aagtgggaat
     4081 ctagaacgta aaatctgaag aaaccgtttt atccgatacg tttccgcacc gacagaccta
     4141 gattcccgct ttcgcgggaa tgacggcgga aaggttgctg tttttccgat aaattcctgc
     4201 cgctcttcgt ttttgggatg gcgggaaata aaacaaaagc gcgcgtatca aaaaacaaca
     4261 atgcaaagaa cggtgttggc aattttaagg tttgcgcctt agccgcactt attcgcaaaa
     4321 aaaccgcacg gcgttgaccg tgcggcttgt tgtctgaagg cttcagacgg cattgcttac
     4381 atcatgccgc ccataccacc catgccgccc atatcgggca tagcaggttt ttcttcaggg
     4441 atttcggcaa tcatgcaatc ggtcgtcagc atcaggccgg cgatggacgc ggcgtgttgc
     4501 agcgcggaac gggttacttt ggcggggtcg agtacgccca tttcgatcat gtcgccgtat
     4561 tcgccggagc ctgcgttgta accgtagttg cctttgcctt ccaacacttt gttcaccacc
     4621 acgctaggtt cgccgcctgc gttggcaacg atttggcgca gcggagactc aacggcgcgc
     4681 aagacgattt gtacgcctgc gtcttggtcg gcattgccgg tgtgcaggtt ttccagagcg
     4741 gcacgggcgc gcaacagggc tacgccgccg cctgcaacca cgccttcttc aacggctgcg
     4801 cgggtcgcgt gcagcgcgtc ttctacgcgg tctttcttct ctttcatttc gacttcggtc
     4861 gcggcaccga ctttgatcac tgccacgccg cctgccaatt tggcaacgcg ctcttgcagt
     4921 ttttctttgt cgtaatcgct ggttgcggtt tcgatttgtt ggcggatttc ggcaacacgc
     4981 gcttcgattt gggctgcgtc gccgaagccg tcgatgatgg tggtgttttc tttaccgatt
     5041 tcgatgcgtt tggcttgtcc caagtcttcc aaagtcgctt tttccagaga caggccgact
     5101 tcttcggaaa tcaccgtgcc gccggtcagg atggcgatgt cttgcaacat ggctttgcgg
     5161 cggtcgccga agcccggggc cttaacggca acggttttca ggatgccgcg gatgttgttc
     5221 acgaccaaag tcgccaaggc ttcgccttct acgtcttcag cgataatcaa gagcggacgg
     5281 ctggctttgg ccacttgttc caaaacaggc aacaggtcgc ggatgttgct gatttttttg
     5341 tcgaacaaca atacaaacgg attgtccaaa gcagcgattt gtttttcagc gtcgttgatg
     5401 aagtaaggag acaggtagcc gcggtcgaac tgcatacctt caaccacgtc cagctcgttt
     5461 tccaaagatt tgccgtcttc aacggtaatc acgccttctt tgccgacttt ttccatcgcc
     5521 tcggcgataa tcgcgccgac ttgttcgtcg gagttggcgg aaatcgagcc gacttgggcg
     5581 atttctttag aagtgtcgca aggtttggcg atgttttgca gctcttcaac caaagcggca
     5641 acggctttgt cgataccgcg tttcaggtcg gtcgggttca taccggcggt aacgtatttc
     5701 ataccttcgg caacgatgga ttgcgccaat acggtggcgg tagtcgtacc gtcgcctgcc
     5761 acgtcgttgg ttttggacgc gacttctttc accatttgcg cgcccatatt ttcaaacttg
     5821 tctttcagtt cgatttcttt ggcgacggtt acgccgtctt tggtgatgtg cgggccgccg
     5881 aaagcgcggt caacgactac gttgcggcct ttggggccca aggttacgcg cacggcgttt
     5941 gccaaaatgt tcacgccgtt taccattttt tggcggactt cattgccgaa ctgtacgtct
     6001 tttgctgcca tttcaattct ccaaaaatca ttaaaactgt ctgataaaac cgtttatgcc
     6061 gtctgaaggc ggtttgccgt ttcagacggc atcatcattc gcacttattc aacgatgccg
     6121 aaaatatctt cttcgcgcat taccaacagc tcttcgccgt cggcttttac ggtttggccg
     6181 ctgtatttgc cgaaaatgat tttgtcgccg actttgacat ccagcggacg gcgcgcgccg
     6241 tctttaccga ttttgcccgc gcccacggcg atgacttcgc ccatatcggg tttttcggcg
     6301 gccgcacccg gcaaaacgat acccgatgcg gttttttctt cagcttccaa gcgtttgacg
     6361 acgacgcggt cgtgtaaagg acggatggtc atatttatgc tccgataaaa tggtttgaaa
     6421 acaatcatct gcccgaacgg ttcggacaga ttgaagtgga aaccgggctg ccgcctgccg
     6481 gccgcccgta tgaatcggca aaattagggt gtgtgcgggc aaattcaagt gaggcggaaa
     6541 aaatttattt ccgccgtttt ttatagtgga ctaaatttaa ggggctgtac tagattagca
     6601 gatatgttac cctcgaaata tgaagataac gcactgcaaa ttaaagaaaa aagtacagaa
     6661 agaactgctc cgtttttttg tactcgaagt taccgcccgt tctgccgccg atattttggg
     6721 tatccatccc aattcggcag cactgttcta ccgtaaaatc cgcacggtta tcaaccatca
     6781 tttagccttg gctgccgatg aggtttttga gggctctgtc gagccggacg aaagcgattt
     6841 cggcggacgg cgtaaaggca gacgtggtcg cggtgcggca ggaaaagtgg ttgtcttcgg
     6901 cattctgaaa cgcaacggac gggtctatac cgttgtcgta aacaatgcca agtctgaaac
     6961 gttactccct gtcatcaaaa agaaaatcat gccggacagt attgtttata ccgatagtct
     7021 gagcagctat gacaagctgg acgtaagcgg ttttatccat caccgcatca accattccaa
     7081 ggaatttgca gaccgtcaga accacattaa cggcattgag aatttttgga atcagtcaaa
     7141 acgcgtcttg cgaaaataca acggaatcga tcgtaaatct ttcccgctgt tcttgaaaga
     7201 atgcgaattt cgatttaact tcggcacacc gtcccggcag ctaaaaatcc tacaggattg
     7261 gtgt
//
LOCUS       DAXIDM010000095         7205 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000095 DAXIDM010000000
VERSION     DAXIDM010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7205
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.095"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(86..955)
                     /locus_tag="ACFOAE_001657"
     CDS             complement(86..955)
                     /locus_tag="ACFOAE_001657"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFC6885109.1"
                     /translation="MSANEYTQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAP
                     ISAKGAKVYGNTAELVRDYPVIFLMVSDYAAVCDILNGVRDGLAGKIIVNMSTISPTE
                     NLAVKALVEAAGGQFAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTF
                     HFGDVGKGSGAKLVLNSLLGIFGEAYSEAMLMARQFGIDTDTIVEAIGGSAMDSPMFQ
                     TKKSLWANREFPPAFALKHASKDLNLAVKELEQVGNTLPAVETVAASYRKAVEAGYGE
                     QDVSGVYLKLAEH"
     gene            complement(1050..1967)
                     /gene="hisB"
                     /locus_tag="ACFOAE_001658"
     CDS             complement(1050..1967)
                     /gene="hisB"
                     /locus_tag="ACFOAE_001658"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004424 - imidazoleglycerol-phosphate
                     dehydratase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HFC6885110.1"
                     /translation="MNLTKTQRQLHNFLTLAQEAGSLSKLAKLCGYRTPVALYKLKQR
                     LEKQAEDPDARGIRPSLMAKLEKHTGKPKGWLDRKHRERTVPETAAESTGTAETQIAE
                     TASAAGCRSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDID
                     ISCKGDLHIDDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLS
                     GRPGLVYNIEFTRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFK
                     AFGRALRMAVEHDPRMAGQTPSTKGTLTA"
     gene            complement(1964..3061)
                     /gene="hisC"
                     /locus_tag="ACFOAE_001659"
     CDS             complement(1964..3061)
                     /gene="hisC"
                     /locus_tag="ACFOAE_001659"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HFC6885111.1"
                     /translation="MKSVRSFIRDDIQAMSAYQIADVPPGFAKLDSMESPVHPFAGHE
                     TLLQEWQARLAAAPIHLYPNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITML
                     TAKPGAAMLAAEPSFVMYRHNAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTF
                     IAYPNNPTGVCFTRAEIEAVIEASDGIVVIDEAYGAFNGDSFLPQAGSIPNLIVMRTV
                     SKIGFAGLRIGYAAGCPEVIGELQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLK
                     NERERMFSELGKICRLNTFPSQANFITIRVPDADLLFDTLKQNRILVKKLHGAHPLLE
                     HCLRITVGSPAQNDAVLNIIRQLYCQPTDFL"
     gene            complement(3107..4396)
                     /gene="hisD"
                     /locus_tag="ACFOAE_001660"
     CDS             complement(3107..4396)
                     /gene="hisD"
                     /locus_tag="ACFOAE_001660"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HFC6885112.1"
                     /translation="MKKLNTQSPDFQAGLKALLAFETAQNPETERIVADICADVQKRG
                     DAALIEYTNKFDQTNAKSIDDLILTQADLKAAFERIPNDVQTALQTAARRVESYHQRQ
                     KMESWSYTDEDGTLLGQQITPLDRVGIYVPGGKAAYPSSVIMNAMPAHVAGVKEIIMV
                     VPTPKGERNDIVLAAAYVAGVTKVFTVGGAQAVAALAYGTETIPQVDKITGPGNAFVA
                     AAKRRVFGVVGIDMVAGPSEILVIADGTTPADWVAMDLFSQAEHDEIAQAILIGTSQA
                     YLDEVEAAMDRLIETMPRRDIIEASLGNRGAMILAKDLDEACEIANYISPEHLELSVE
                     NPQEWAKKIRHAGAIFMGRYTGESLGDYCAGPNHVLPTSRTARFSSPLGTYDFQKRSS
                     LIQVSEHGAQKLGETASVLAHGESLTAHARAAEFRMK"
     gene            complement(4393..5292)
                     /locus_tag="ACFOAE_001661"
     CDS             complement(4393..5292)
                     /locus_tag="ACFOAE_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HFC6885113.1"
                     /translation="MVAKIKKFSDSTLSVLNNGERRFYVYCLTDLKKDKILYIGKGCG
                     NRIFEHEWVASRSQDPVSGEIIDRKLKAISKCKKLGRYIISYHLTEVEALAAESALIH
                     FVKSVLGKKLKNKIAGHGPGGISVEELDRRFGFSSLPLNEINPDGLILAIKIHNAFDL
                     DTDEELDYLFDNQDDANLKSRTLGNWVIGKDVASKVKYVIGVHTGLQNAVVSAYEVDG
                     FETMVEETKNGRKQSRYRFRTTSRSEEVLAKLGLQQKCLPELKFGSGGEKAYIRPKTE
                     TETEQENIQTTPNPKIKKEKTKS"
     gene            complement(5397..6050)
                     /gene="hisG"
                     /locus_tag="ACFOAE_001662"
     CDS             complement(5397..6050)
                     /gene="hisG"
                     /locus_tag="ACFOAE_001662"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003879 - ATP phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HFC6885114.1"
                     /translation="MQDNALTIALSKGRIFEETLPLLAAAGIVPTEEPEKSRKLIIGT
                     NHENIRLVIVRATDVPTYVRYGAADFGIAGKDVLIEHGGTGLYRPLDLEIAKCRMMVA
                     VRKGFDYEAASQPGCRLKIATKYPEIAASHFAGKGVHVDIIKLYGSMELAPLVGLSDA
                     IVDLVSTGNTLKANGLEAVEHIVDISSRLVINKAALKTKYALLEPIIQAFGGAVKAK"
     gene            complement(6129..6782)
                     /locus_tag="ACFOAE_001663"
     CDS             complement(6129..6782)
                     /locus_tag="ACFOAE_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCO family protein"
                     /protein_id="HFC6885115.1"
                     /translation="MFSVPRSFLPGVFVLAALAACKPQDNSAAQAASSSASASAAENA
                     AKPQTRGTDMRKEDIGGDFTLTDGEGKPFSLSDLKGKVVILSFGFTHCPDVCPTELLT
                     YSDTLKQLGGQAKDVKVVFVSIDPERDTPEIIGKYAKQFNPDFIGLTATGGQNLPVIK
                     QQYRVVSAKVNQKDDSENYLVDHSSGAYLIDKNGEVAIFSPYGSEPETIAADVRTLL"
     gene            7059..7143
                     /locus_tag="ACFOAE_001664"
     tRNA            7059..7143
                     /locus_tag="ACFOAE_001664"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7093..7095,aa:Leu,seq:caa)
BASE COUNT         1477 a         1712 c         2126 g         1890 t
ORIGIN      
        1 tcataatcgg gactgatttt aagcgtgggg tgataaaaat gccgtctgaa atatgttcag
       61 acggcatatt gtttggaaag ggaagtcagt gttctgccag tttcaggtaa acgccggaaa
      121 cgtcctgttc gccgtagccg gcttcgactg ctttgcggta gctggcagca acggtttcga
      181 cggcgggcag ggtgttgcct acctgttcaa gctctttgac ggcgaggttg aggtctttgg
      241 aggcgtgttt gagggcgaag gcgggtggga attcgcggtt tgcccacagg gattttttgg
      301 tttggaacat gggcgagtcc attgccgagc cgccgatggc ttcgacgatg gtgtcggtat
      361 cgatgccgaa ctgccgcgcc atcagcatcg cttcgctgta cgcttcgccg aaaatgccca
      421 agagcgagtt caagacgagt ttcgcgcccg aacctttgcc gacatcgccg aaatggaagg
      481 tttttttgcc gacgagggaa aatatttttt gcagcgggtt taaaacggct tcgctgccgc
      541 cgaacagaat cagcagcgtg ccgttggtgg cgggcccgac cgatccggaa acgggtgctt
      601 cggcaaactg tccgcctgcg gcttcgacaa gtgctttgac ggcgaggttt tcggtcgggg
      661 agatggtgct catgttgacg atgattttgc cggccaatcc gtcgcggact ccgttcagga
      721 tgtcgcacac ggcggcatag tcggaaacca tcaggaaaat gacgggatag tcgcggacga
      781 gttcggcggt gttgccgtaa acttttgcgc ctttggcgga gatgggggca gttttgtcgg
      841 gcgagcggtt gtatacgccg acttcgatgc cgccgtccaa gagccgcgtt accataggca
      901 gacccatttg ccctaagcct atccagccta tttgtgtgta ttcgtttgcg gacatgatgt
      961 ttactccttt tctgtttgta gtgtagtgta atcttatctg ttccgatacc gtctgaaaag
     1021 cctgagggtg tttcagacgg tatggttttt tatgcggtca gcgtgccttt ggtcgagggg
     1081 gtctgtcctg ccatgcgcgg gtcgtgttcg actgccatac gcagggcacg cccgaaggct
     1141 ttgaatacgg tttccgcctg atggtgggcg tttttgccgc tgaggttgtc gatgtgcagg
     1201 gtcatcatac tgtggttgac gatgccgtgg aaaaattctt caaacaaatc gacatcgaaa
     1261 cgtccgatta gtgcgcgggt aaattcgatg ttgtacacga gtccggggcg gccggaaagg
     1321 tcgatgacga cgcggctgag ggcttcgtcg agcgggacgt aggaatgtcc gtaacggcgg
     1381 atgccttttt tgtcgccgag tgcctgccgg attgcttgtc cgagtgtgat gccgatgtct
     1441 tcggcggtgt ggtggtcgtc gatgtgcagg tcgcctttgc agctgatgtc gatgtcaatc
     1501 atgccgtggc gggcgatttg gtcgatcatg tgttcgagga agggtacgcc ggtatccagc
     1561 ctgcttttgc cgctgccgtc gaggttgatg gagacggtga tttgggtttc gcaggtattg
     1621 cggttgacgg taacgctgcg gcagccggca gcagatgcgg tttcggcaat ttgggtttcg
     1681 gcagttccgg tgctttctgc ggcggtttcg gggacagtgc gttcgcggtg ttttctgtcg
     1741 agccagcctt tgggtttgcc ggtgtgtttt tcgagttttg ccatcaggct gggacggatg
     1801 ccgcgtgcat ctgggtcttc tgcctgcttt tcaaggcgtt gtttgagttt gtagagtgcg
     1861 acgggggtac ggtagccgca gagtttggcg agcttggaca gcgaacctgc ttcttgggcg
     1921 agggtcagaa agttgtgcag ttggcgttgt gttttagtca aattcatagg aaatccgttg
     1981 gttggcagta aagttggcga atgatgttga gaacggcatc gttttgtgcg gggctgccta
     2041 cggtaatgcg caggcagtgt tccaaaagcg ggtgcgcgcc atgcagtttt ttaaccaaga
     2101 tgcggttttg tttgagcgtg tcaaacaaca aatcggcatc gggtacgcgt atggtaatga
     2161 agtttgcctg acttggaaag gtgttcagac ggcatatttt gcccaattcg gagaacatcc
     2221 gttcgcgttc gtttttcagg ctgtcgatgt tggcagagat gatgccgtag tgttgcaggg
     2281 cgagtttggc ggtggtcagg ctcagttggt tcatattgta gggcggcagg attttttgca
     2341 gttcgccgat gacttcgggg cagcctgccg catagccgat acgcagtccg gcaaaaccga
     2401 ttttgctgac ggtacgcatg acgatgaggt tgggaatgct gcccgcctgc ggcaggaagc
     2461 tgtcgccgtt gaatgcgccg taggcttcgt cgatgacgac gatgccgtct gaagcttcga
     2521 tgacggcttc gatttcggca cgcgtgaaac atacgccggt ggggttgttg gggtaggcga
     2581 taaaggtcag ggcagggcgg tgcttcctga cggcttcgag gacggcgggc aggttgaggg
     2641 tgaaatctcc gttcagtgga acgccgacat aatccatgcc gtacagcgcg gcgttgtggc
     2701 ggtacatgac gaaactgggt tcggctgcca acattgccgc gcccggtttg gcggtcagca
     2761 tcgtgatgaa ctgtatcagc tcgtccgagc cgttgcccag cgcgatgtcg gcgcagtcgg
     2821 gaatgtcgaa cgccgaacgt aatgcttcct gtaaaccgct gccggaggga ttggggtaaa
     2881 gatggatggg cgcggcggca agccgtgcct gccattcctg caacagcgtt tcatgtccgg
     2941 caaaagggtg gacgggactt tccatcgaat cgagtttggc aaagccgggc ggaacgtcgg
     3001 caatctgata tgccgacata gcttgtatgt cgtcgcggat gaaggagcgg acggatttca
     3061 tcgtgtttcc ttaatggttg gaatatgcct gtacgccgtt tcggcattat ttcatacgga
     3121 actctgccgc gcgggcgtgg gcggtcaggc tttcgccgtg tgccagcacg ctggcggttt
     3181 cgcctaattt ttgcgcgccg tgttccgaaa cctgaatcag gctggagcgt ttttggaaat
     3241 catatgtccc caaaggcgag gaaaagcggg cggttcggct ggtgggcaat acatggtttg
     3301 gaccggcgca gtagtcgccg aggctttcgc cggtgtagcg tcccatgaaa atcgcaccgg
     3361 cgtggcggat ttttttcgcc cattcctgcg gattttcgac tgacagttcc aagtgttcgg
     3421 gggaaatgta gttggcgatt tcgcaggctt cgtccaagtc tttggcgagt atcatcgcgc
     3481 ccctgttgcc gagcgaggct tcgatgatgt cgcggcgcgg catagtttcg atcaggcggt
     3541 ccatagcggc ttctacttcg tcgagatacg cttgcgacgt gccgatgagg atggcttggg
     3601 caatttcgtc gtgttcggcc tggctgaaca aatccatcgc cacccaatcg gcaggtgtcg
     3661 tgccgtcggc gatgaccagg atttcagacg gccccgccac catgtcgatg ccgaccacgc
     3721 cgaacacgcg gcgtttggcg gcggcgacga aggcgttgcc tggaccggtg attttatcga
     3781 cttgggggat ggtttccgtg ccgtaggcga gggcggcaac cgcctgcgcg ccgccgacgg
     3841 tgaagacttt ggttacgccg gcgacgtatg cggcggcaag tacgatgtcg ttgcgttcgc
     3901 cttttggtgt cggcacgacc atgatgattt ctttcacacc tgcgacgtgg gcgggcatgg
     3961 cgttcatgat gacggaactc ggatacgccg ccttgccgcc ggggacgtaa atgccgacgc
     4021 ggtcaagcgg tgtgatttgt tgtcccaaca gcgtgccgtc ttcatcggtg tagctccacg
     4081 attccatttt ttggcgttgg tggtagcttt cgacacggcg ggcggcggtc tgcaatgccg
     4141 tctgaacgtc gttcggaatg cgctcgaacg ccgctttcaa atcggcttgc gtgagtatta
     4201 aatcatcgat gcttttagcg tttgtctgat cgaatttgtt ggtgtattca atcaaagccg
     4261 catcgccgcg cttttgcacg tcggcgcaaa tgtcggcgac gatgcgttcg gtttcggggt
     4321 tttgcgcggt ttcaaaagcc agcagggctt tgagtccggc ttggaaatcg ggcgattggg
     4381 tgttgagttt tttcatgatt tggttttttc cttttttatt tttggattgg gggtcgtctg
     4441 aatattctct tgttcagttt ctgtctctgt tttgggtctg atatacgctt tttctccccc
     4501 gctaccaaac ttcaattcgg gcaggcattt ttgttgcaga ccgagtttgg ctaatacctc
     4561 ttcgctacga gaggtagtgc ggaaacggta acgggattgt tttctaccgt ttttggtttc
     4621 ctcaaccatt gtttcaaaac cgtccacttc gtatgcactg acaacagcgt tttgcagacc
     4681 ggtgtgaacg ccgataacgt atttcacttt tgaagcaaca tctttaccga taacccagtt
     4741 gcccaacgta cgcgatttga ggttggcatc gtcttggttg tcgaaaaggt agtctaattc
     4801 ttcgtcagta tctaaatcga aagcattgtg gattttgatg gcgagaatca gcccgtcggg
     4861 gttaatctcg ttaagtggga gagaagagaa tccaaagcgg cgatctagtt cttctacgct
     4921 aataccaccc ggaccatgcc cggcaatttt atttttgagt tttttaccca agacagattt
     4981 aacaaaatga attaaggcag attcggcggc gagtgcttcg acttcagtca gatgatagct
     5041 gatgatatag cgaccgagtt tcttgcattt ggagatggct ttgagtttcc gatcgataat
     5101 ctcgccggag actgggtctt gtgaacgact agcaacccat tcatgctcga agatacgatt
     5161 accgcagcct ttgccgatgt agaggatttt gtcttttttc aggtcggtca gacaatagac
     5221 ataaaaccga cgctcgccgt tattcaaaac ggaaagggtt gaatctgaga atttttttat
     5281 ttttgcaacc attttaactt ctcctactac agtttactgt cggtgatatt ttcagacgac
     5341 ctgtcggcgg gaacggatag ggtcgtctga aaacgcatct ttattcaaat gaatgcttac
     5401 ttcgccttca ctgcgccgcc gaacgcctga ataatcggct ccagcagcgc gtatttcgtt
     5461 ttcaaagcag ccttgttgat caccaggcgg ctggaaatgt cgacgatgtg ttcgactgct
     5521 tccaagccgt ttgccttcaa ggtgttgccc gtcgaaacca agtccacaat cgcatcgctc
     5581 aagccgacca gcggcgcaag ttccatcgag ccgtacagtt tgataatgtc cacatggaca
     5641 cccttgccgg caaaatggga tgccgcgatt tcaggatact ttgtggcaat cttcagacgg
     5701 catccgggtt gcgaagctgc ttcgtaatca aaccctttac gcacagcaac catcatgcgg
     5761 cacttggcaa tctccaaatc caaaggccgg taaagccccg tgccgccgtg ttcgatcagc
     5821 acgtctttgc ccgcaatgcc gaagtccgcc gcgccgtagc ggacataagt cggcacatcg
     5881 gttgcgcgga caatgacaag gcggatgttt tcatggttcg tcccgataat cagcttgcgc
     5941 gatttttcag gctcttcagt cggaacaatg ccggcagcgg caagcagcgg cagcgtctcc
     6001 tcaaaaatgc gccccttgga taaggcgatg gtcaaagcat tatcctgcat ggtgtggatg
     6061 tcctttgtcg gttgaaacaa taatgccgtc tgaacaggcg ccgacggtgc agacggcata
     6121 cggttttatc agagcagggt ccttacatcg gcagcaatcg tttccggctc gcttccgtaa
     6181 ggcgagaaaa tggcaacctc accgtttttg tcgatgagat acgcaccgga agagtggtcg
     6241 accaaatagt tttcgctgtc gtctttttga ttgactttgg cagaaaccac gcggtattgc
     6301 tgcttgatga ccggcaggtt ttggccgccc gttgccgtca gaccgataaa gtccggattg
     6361 aactgtttgg catacttgcc gatgatttca ggcgtgtcgc gttccggatc gatgctgacg
     6421 aacaccactt tcacgtcctt agcttgcccg cccaactgct tcaacgtgtc gctgtacgtc
     6481 aaaagctctg tcgggcagac atcgggacag tgcgtaaagc cgaaagacag aatcacgacc
     6541 ttgcctttca aatcgctcag gctgaaaggc ttgccttcgc cgtcggtcag cgtgaaatcg
     6601 ccgccgatgt cttccttacg catatccgta ccgcgcgttt gcggctttgc cgcattttcc
     6661 gcagctgacg cggatgcact tgaagaagcg gcttgcgccg cactgttgtc ttgaggtttg
     6721 caggcggcaa gcgcggcaag tacgaaaacg cccggcaaaa aggaacgcgg tacggaaaac
     6781 atgacaatct cccaagaata aatagcaaaa cctgattcgt acggaatttg aatatttcca
     6841 tcttaacgcg tttggcagat ttaatgtagt atttttttac gttgtttgca cggcaggaat
     6901 tgccgaatca tacagaatct ttggagcgga aagaacagta agattaaaat aataaaaatt
     6961 ctatttaaaa tcaaaaataa aataaaaaca gataaaataa tttcaaaaaa aaggtttaca
     7021 gaatttcaaa agccattata atgacgactt cttcaccagc ccaggtggcg aaattggtag
     7081 acgcagggga ctcaaaatcc cccgccgcaa ggtgtgtcgg ttcgagtccg accctgggca
     7141 ccacaaccgc ttttagagcg gttatttttt tgtctattgc tgtttaatga aatagataaa
     7201 actaa
//
LOCUS       DAXIDM010000096         7200 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000096 DAXIDM010000000
VERSION     DAXIDM010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 7200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7200
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.096"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            325..1770
                     /gene="zwf"
                     /locus_tag="ACFOAE_001665"
     CDS             325..1770
                     /gene="zwf"
                     /locus_tag="ACFOAE_001665"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFC6885116.1"
                     /translation="MSTQTNFDLVLFGATGDLAMRKLLPCLYQAHVAGLLHPEGRILG
                     VSRSELDTEGFLAKVETSSKIHVKENFSDEAWASFVERLAYLKVDVTQPDDFAALGDL
                     VKARKETDNVVIYLSTAPKFFAQTCENLAKIGLNADNVRVVLEKPLGTDLASSQQINT
                     DVARYFKEGQIYRIDHYLGKESLQNLLALRFANVMFEPLWNNKYIESVQLTIAEQLGV
                     EERGEFYDITGALRDMVQNHLMQMLCMTAMEAPASLDADAVRDEKVKVIKSLKPLTVE
                     SVNENVVRGQYTAARGMNGYLEEINVPQDSFTETYVAIKAEIENERWKGVPFYLRTGK
                     RMAGKVAEIVLNFKDLNSHIFEGSRTAPNRLVIELQPYESVRLYTQMKTPGAGNKVET
                     VPLATDLGKALESRRAEAYERLLLDVINGKLALFNRRDELEAAWEYVMPILENWTNNT
                     TPPHGYGAHSWGPEAARELLARDGHKWHEEQ"
     gene            2050..2745
                     /gene="pgl"
                     /locus_tag="ACFOAE_001666"
     CDS             2050..2745
                     /gene="pgl"
                     /locus_tag="ACFOAE_001666"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013448834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HFC6885117.1"
                     /translation="MFVWHEYENAAEAAQSLADAVADALQGALDEKGGAVLAVSGGRS
                     PIAFFNALSQKDLDWKNVGITLADERIVPTVHADSNTGLVREYLLKNKAEAAMWIPMV
                     EDGKTETELHPDAVVDYALKHYKQPDVLVLGMGNDGHTASIFPKAPQFQTAIDGSAGV
                     ALVHTTPVTAPHERVSMTLDAIAHTGHVFLAIRGEEKKAVFDQAAQGENREYPINLVL
                     NHQGVNCHVFYAE"
     gene            2726..3712
                     /locus_tag="ACFOAE_001667"
     CDS             2726..3712
                     /locus_tag="ACFOAE_001667"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005536 - D-glucose binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HFC6885118.1"
                     /translation="MSSTPNKQAGYPRLVADIGGTNARFALETAPRVIEKAAVLPCKD
                     YDTVTDAVRAYLNQSGATAVRHAAFAIANPILGDWVQMTNHHWAFSIETTRQTLGLDT
                     LILLNDFTAQALAVTQTSSKDLMQVGGQKPVEFAPKAVIGPGTGLGVSGLVHSHAGWV
                     ALAGEGGHTSFPPFDDMEVLIWQYAKNKYGHVSAERFLSGAGLSLVYEALAAKQKAKP
                     AKLMPSEITEKALSGASPLCRQTLDIFCAMLGTVASNLALTLGARGGVYLCGGIIPRV
                     LEYFKTSPFRSRFENKGRFEAYLAAIPVYVVLSEFPGISGAAAALDNHLRNV"
     gene            3762..4610
                     /gene="hexR"
                     /locus_tag="ACFOAE_001668"
     CDS             3762..4610
                     /gene="hexR"
                     /locus_tag="ACFOAE_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HFC6885119.1"
                     /translation="MLSKISESLANLSGAERKVAECALAEPKWFVHAAVAEIAERASV
                     SQPTVIRFCRSLGYKGLPEFKLALSASIGHEGMPYVHEELNADDDMASVVEKVLGNAA
                     ASLLGERRFLKESELENAIATLMHARRVEFYGVGNSGIVAQDAQHKFFRFGMSTVAYV
                     DTHTQLMAASVLSDQDVLVAISNTGSSIELLDAVSIAKENGASVIALTRNDSPLAQLA
                     DCVLSVATQENAELYTPMVSRLLQLAVIDILAIGLALRLGDAASLQLQKSKKSIHNKH
                     IDYDKD"
     gene            4731..6377
                     /gene="pgi"
                     /locus_tag="ACFOAE_001669"
     CDS             4731..6377
                     /gene="pgi"
                     /locus_tag="ACFOAE_001669"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFC6885120.1"
                     /translation="MKHFHDLPAWPKLWNHFDDSKTLHMREMFEQDPQRAERYWLQVG
                     GLTLDYSKNRINDETMSLLFELAREAGVPERMRQMFHGEKINTTENRAVLHVALRNRT
                     NSPIVVDGEDVMPKVNRVLQRMGEFAHEVRSGSWLGYTNQVITDVVNIGIGGSDLGPL
                     MMCTALKPFGHPRLNMHFVSNVDGSQLRDVLSKVHPETTLFIIASKTFTTQETLTNAL
                     TAREWFLNHAGDESAVAKHFVAVSTNQKAVAEFGIDTANMFEFWDWVGGRYSLWSAIG
                     LPIMLYLGEENFIEMLNGAHLMDQHFINTPLERNLPAILALIGIWYINYYGGGSHVIA
                     PYDQHLHRLPKFIQQLDMESNGKQVTLDGKAVGHETSPIIWGETGINGQHAFFQLLHQ
                     GTHITPIDLIASLEKRSNLPGHHEILLANVFAQAEAFMRGKTPDEVRAELKAQGMDEA
                     RIEELVPHKTFSGNRPTNLILMDKVNPRNMGSLIAMYEHKTFVQGIIWGINSFDQWGV
                     ELGKQLAKTILGELTGETGPQKHDSSTERLINLYLQTNRK"
     gene            6391..6942
                     /locus_tag="ACFOAE_001670"
     CDS             6391..6942
                     /locus_tag="ACFOAE_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HFC6885121.1"
                     /translation="MPSERRPFQTAFLSNRKTVGKLAERVQSRYDGLHKFKHVCSAAM
                     ALIKEPLDKAKQRNEELEAAEEAAAQEALGREQEVDRVSEWEERYKLSRSEFEQFWKG
                     LPQTVQNKLQASQKTWKSGMDKICANNAKAEGETPNGIKFSELACKTAETEARLEELH
                     NRKKALIDEMAREADKKELPKRL"
BASE COUNT         1880 a         1909 c         1907 g         1504 t
ORIGIN      
        1 aaaaggtatg ccgtctgaaa gtgggaagcg ggtgttatta tagtacaaaa tttgtaattt
       61 tgttacaaaa aaatcagaca tcgaaaagaa atttgattta aatcgcagaa tctttcgatt
      121 gttgtaacgg aataggggaa acctgcccga tttttggact aggtcaaata aattgtaaaa
      181 atgggaatag acaaaaagtg tagcggtgtg tagtattact actcattatg ccgcctgcct
      241 ttgtttccga tattgcgatg cagcgtgatg ggggaaacag gtttcagacg gcatcgaaaa
      301 attctttcct gacgagataa tacgatgagt acacaaacaa attttgattt ggtgttgttc
      361 ggtgcgaccg gcgatttggc gatgcgcaag ctgttgccct gtctgtacca ggcgcatgtt
      421 gccggtctgc ttcatcccga agggcgtatt ttaggggtca gccgcagcga gttggatacc
      481 gaaggttttc tggcgaaggt ggaaaccagt tccaaaatcc atgtgaaaga aaatttttcc
      541 gatgaggctt gggcatcgtt tgtcgaacgt ctcgcatatc tcaaagtcga tgttacgcag
      601 ccggacgatt ttgccgcttt gggcgatttg gtcaaagcgc gcaaagaaac cgacaatgtc
      661 gtcatctatc tttccaccgc gccgaaattc ttcgcgcaaa catgtgaaaa ccttgccaaa
      721 atcggtttga acgccgacaa cgtgcgtgtg gttttggaaa aaccgttggg tacggatttg
      781 gcttcttccc agcaaatcaa taccgatgtt gcgcgttatt tcaaagaagg gcaaatttac
      841 cgcatcgacc actaccttgg caaagaaagc ctgcaaaacc tgcttgcgct gcgttttgcc
      901 aatgtaatgt tcgagccgct gtggaacaat aaatacatcg aaagcgtgca gttgaccatc
      961 gccgagcagt tgggcgtgga agagcgcggc gagttttacg acattaccgg cgcgttgcgc
     1021 gatatggtgc aaaaccattt gatgcagatg ctgtgcatga ctgcgatgga agcccccgcc
     1081 agcttggatg ccgacgcggt gcgcgatgaa aaagtcaaag tcatcaagtc attgaagccg
     1141 ctgaccgtcg agtctgtcaa tgaaaacgtc gtgcgcggac aatataccgc cgccagaggc
     1201 atgaacggct atcttgaaga aatcaacgtt ccgcaagaca gctttaccga aacctacgtc
     1261 gccattaaag ccgaaatcga aaacgaacgc tggaagggcg ttcccttcta cctgcgtacc
     1321 ggcaaacgca tggcgggcaa agtggcggaa atcgttttga acttcaaaga tttgaacagc
     1381 catatttttg aaggcagccg caccgcgccc aaccggctcg ttatcgagtt gcaaccatat
     1441 gaatccgtgc gcctctatac gcagatgaaa accccggggg caggaaataa ggtcgaaacc
     1501 gtgccgctgg caaccgattt gggcaaagca ttggaaagcc gccgcgcgga agcttacgag
     1561 cgcctgctgc tggatgtgat taacggcaaa ctcgctttgt ttaaccgccg cgacgaactc
     1621 gaagccgcgt gggaatatgt gatgccgatt ttggaaaact ggacaaataa caccacgccg
     1681 ccgcacggct acggcgcaca ctcgtggggg cctgaagccg cgcgcgaact attggcgcgc
     1741 gacggacaca agtggcacga agagcagtaa tacaataatg cgttcagacg gcatggggtt
     1801 tgaaatgccg tctgaacgta agtaaagcag tatagtggat taacaaaaat caggacaagg
     1861 cgacgaagcc gcagacagta caaatagtac ggcaaggcga ggcaacgctg tactggttta
     1921 aatttaatcc actataaaaa gcagtcccga tatttggtat caaaagcata aacaactgtt
     1981 cggccgacat attgctcaac ccgtttccat aacggaatat gccgtctgaa ataaaaaaag
     2041 gacacaaata tgtttgtttg gcacgaatac gaaaatgcgg cagaagcggc gcagtctttg
     2101 gctgacgcag tggcggatgc tttgcagggc gcactggacg agaagggcgg tgcggtgttg
     2161 gcagtttccg gcggacgttc gccgattgca tttttcaacg ccctgtcgca aaaagatttg
     2221 gattggaaaa acgtcggcat caccttggca gatgaacgca tcgtgccgac cgtccacgcc
     2281 gacagcaata ccggtttggt gcgcgaatac ctgttgaaga acaaagcgga agcggcaatg
     2341 tggattccta tggtggaaga cggaaaaact gaaaccgaat tacatcccga tgctgttgtc
     2401 gattatgcac tgaaacatta caaacagccc gatgttttgg ttttgggtat gggaaacgac
     2461 gggcatacgg cttcgatttt cccgaaagct ccgcagtttc agacggcaat cgacggttcg
     2521 gcaggtgtcg cgctggtgca taccacgccc gttaccgcgc cgcacgagcg cgtcagtatg
     2581 accttggatg cgattgccca tacggggcat gtgtttttgg cgatacgggg cgaagagaaa
     2641 aaagccgtgt tcgaccaagc cgcacaaggc gaaaaccgcg aatatccgat caacctcgtt
     2701 ttgaaccatc aaggagtgaa ctgccatgtc ttctacgccg aataaacaag ccggatatcc
     2761 ccgactggtc gccgatatcg gcgggacgaa tgcacgcttt gcgctggaaa ccgcgccgcg
     2821 cgtcattgaa aaagccgccg tgcttccgtg taaagactac gatacggtta ccgatgcggt
     2881 gcgtgcctat ctgaatcaaa gcggtgcaac agccgtacgg cacgcggcat ttgccatcgc
     2941 caacccgatt ttgggcgact gggtgcagat gaccaaccac cattgggcgt tttccatcga
     3001 aaccacccgt cagactttgg ggctggacac cctcatcctt ttgaacgact ttaccgcgca
     3061 ggcattggcg gtaacgcaga cttcaagcaa agacctgatg caggtaggcg ggcaaaagcc
     3121 tgtcgaattt gcccccaaag ccgttatcgg ccccggtacc ggcctgggcg tgagcggatt
     3181 ggtgcacagc cacgcaggct gggtggcttt ggcgggcgag ggcgggcata ccagtttccc
     3241 gccgtttgac gatatggaag tgctgatttg gcagtacgcc aaaaacaaat acggccatgt
     3301 ttccgccgaa cgctttttga gtggcgcggg cttgagcttg gtttacgagg ctttggctgc
     3361 aaaacagaaa gccaaacccg ccaaactgat gccgtctgaa atcacggaaa aggctttgag
     3421 cggagcgtcg cctttgtgcc gtcagacttt ggacatcttc tgcgccatgc tcggcacggt
     3481 tgcttccaac ctcgccctga cgctgggcgc gcgcggcggc gtgtacctgt gcggcggcat
     3541 tattccccgc gtgttggaat atttcaaaac ttccccgttc cgcagccgtt tcgagaacaa
     3601 gggcaggttt gaagcatatc ttgccgcgat tcccgtgtat gtcgtcttga gcgagttccc
     3661 cggaatttcc ggtgcggctg cggctctcga caaccatttg agaaacgttt aaccacagcg
     3721 gctccttgca gcggggctgc attatcgaag ggcatatcat tatgttaagc aaaatcagcg
     3781 aatcactggc aaacctttcc ggtgcggaac gcaaagtcgc cgaatgtgca ttggcggaac
     3841 ccaaatggtt cgttcatgcc gccgttgccg aaattgccga acgtgcgtcc gtcagccagc
     3901 cgaccgtcat ccgattctgc cgcagcttgg gttataaagg gctgcccgag ttcaagctcg
     3961 ccttgtccgc cagcatcggt catgagggta tgccctatgt ccacgaagaa ctcaatgccg
     4021 acgacgatat ggcaagcgtg gtcgagaaag tgttgggcaa tgccgccgcc tcgctgttgg
     4081 gcgaacgccg cttcctgaaa gagtcggagc tggaaaacgc cattgccacg ctgatgcacg
     4141 cccgtcgcgt cgagttttac ggtgtcggca attccggtat cgttgcgcag gacgcgcaac
     4201 acaagttttt ccgtttcgga atgtccacgg tcgcctatgt cgatacgcac acgcagctga
     4261 tggcagcatc cgttttgagc gatcaggatg ttttggttgc catttccaac acgggttcgt
     4321 ctatcgaact tttggatgcg gtcagcatcg ccaaagaaaa cggcgcgtcc gtcatcgcac
     4381 tgacccgcaa cgattcgcct ctggcgcaac ttgccgactg cgtgttgagc gttgccacac
     4441 aggaaaatgc cgaactctac acgcccatgg tttcccgcct cttgcagctt gccgtcatcg
     4501 acattctcgc catcggactt gccctgcgct tgggcgatgc tgccagcctg caattgcaga
     4561 aaagcaaaaa aagcatacac aacaagcaca tcgattacga caaagattga ccttcagacg
     4621 gcatcccaca aatgccgtct gaaatgccga acaacggccg tcggcggctt gcggcagttt
     4681 ccggcagcct tttcatccca caacaaaaaa cctcattcag gagcatatag atgaaacact
     4741 ttcacgactt acccgcatgg ccgaaattgt ggaaccactt tgacgacagc aaaacattgc
     4801 atatgcgcga aatgttcgag caagacccgc agcgtgcgga acgctactgg ctgcaagtcg
     4861 gcggactgac gctggactac tccaaaaacc gcatcaacga cgaaaccatg tcgcttttgt
     4921 tcgagttggc gcgtgaagca ggcgtgccgg agcggatgcg gcagatgttc cacggcgaaa
     4981 aaatcaatac gacggaaaac cgcgccgtcc tccacgtcgc ccttcgcaac cgcaccaatt
     5041 cgccgattgt ggttgacggt gaagatgtga tgccaaaagt caaccgcgtt ttgcaacgta
     5101 tgggcgaatt tgcacacgaa gtccgcagtg gaagctggct gggctatacc aaccaagtca
     5161 ttaccgacgt tgtcaacatc ggcatcggcg gatcggattt gggcccgttg atgatgtgta
     5221 ccgcgctcaa acctttcggt catccacgcc tcaatatgca cttcgtctcc aacgtggacg
     5281 gctcgcaact gcgcgacgta ttgtccaaag tccaccccga aaccacgctg ttcattatcg
     5341 cctccaaaac ctttaccacg caggaaacgc tgaccaacgc gctgaccgcg cgcgaatggt
     5401 ttttgaatca tgcgggcgat gaaagcgccg tcgccaaaca tttcgttgct gtttccacca
     5461 accaaaaagc cgttgccgaa ttcggcatcg acaccgccaa tatgtttgaa ttttgggact
     5521 gggtcggcgg ccggtacagc ctgtggtccg ccatcggatt gccgattatg ctgtatctcg
     5581 gcgaagaaaa cttcatcgaa atgctcaacg gcgcgcacct gatggaccaa catttcatca
     5641 acactccgct cgagcgcaac ctgcccgcca tcctcgccct tatcggcatc tggtacatca
     5701 actactacgg cggcggaagc cacgtcatcg caccttacga ccaacacctc caccgcctgc
     5761 ccaaattcat ccagcagctc gatatggaaa gcaacggcaa acaggttacg ttggacggca
     5821 aagcagtcgg acacgaaacc tcgccgatta tttggggcga aacgggcatc aacggccagc
     5881 acgccttctt ccaactgctg caccaaggca cgcacatcac ccccatcgac ctcatcgcct
     5941 cgcttgaaaa acgcagcaac ctgcccggac accacgaaat cctgcttgcc aacgtcttcg
     6001 cccaagcaga agcctttatg cgcggcaaaa cccccgacga agtccgcgcc gaactcaaag
     6061 cgcagggtat ggatgaggcg cgtatcgaag agctggttcc gcacaaaacc ttctccggca
     6121 accgcccgac caacctcatc ctgatggata aggtcaaccc ccgcaatatg ggcagcctga
     6181 ttgccatgta cgaacacaaa accttcgtac aaggcatcat ttggggcatc aacagcttcg
     6241 accagtgggg cgtggaactc ggcaaacaac tggctaaaac cattttgggc gaactgaccg
     6301 gcgaaaccgg gccgcaaaag cacgacagtt cgaccgaacg cctgatcaac ctctacctgc
     6361 aaaccaaccg caaataaaac ctgcggaaaa atgccgtctg aacgccgacc gtttcaaacg
     6421 gcatttttat cgaacaggaa aaccgtcggt aaacttgcag agcgtgtgca atcccgatat
     6481 gatggtttgc ataaatttaa acatgtatgt tccgcagcta tggcactgat taaagagccg
     6541 ttggacaaag cgaaacaaag gaacgaagaa cttgaagcgg cagaagaagc ggcggcgcag
     6601 gaggcattgg gtcgggagca ggaagtcgac cgcgtatccg aatgggaaga acgctacaag
     6661 ctgtcgcgca gcgagttcga gcaattctgg aaaggattgc ctcaaaccgt acagaataag
     6721 ctgcaagcct cacagaaaac atggaaaagc gggatggata aaatctgtgc caacaatgcg
     6781 aaagctgaag gtgaaacgcc aaacggcata aaattcagcg aactggcatg caaaacggcg
     6841 gaaaccgaag cacgcttgga agagctgcac aaccgtaaaa aagcccttat cgacgaaatg
     6901 gccagggaag cggacaagaa agaactgcca aagcggctct gaacagcgcg gttcaggcac
     6961 tgcccgccga tattgccgaa accgtcatgc ccgagtaccg caactgacaa aacggtttga
     7021 atgccaaatg cgccgacggc gacgaatacg gcgtggcaca atctgactgc cgtaccagag
     7081 aaatcaatgc gaaaaccaaa gaaatccaag gttatctgat tgactgaaac ttggatgcgg
     7141 gaatgtcggc ggcttttgcg tttttgtcgt ttttatagtg aattaaattt aaaccgatac
//
LOCUS       DAXIDM010000097         6993 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000097 DAXIDM010000000
VERSION     DAXIDM010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6993
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.097"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            57..1295
                     /gene="mtrC"
                     /locus_tag="ACFOAE_001671"
     CDS             57..1295
                     /gene="mtrC"
                     /locus_tag="ACFOAE_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit MtrC"
                     /protein_id="HFC6885122.1"
                     /translation="MAFYAFKAMRAAALAAAVALVLSSCGKGGDAAQGGQPAGREAPA
                     PVVGVVTVHPQTVALTVELPGRLESLRTADVRAQVGGIIQKRLFQEGSYVRAGQPLYQ
                     IDSSTYEANLESARAQLATAQATLAKADADLARYKPLVAAEAVSRQEYDAAVTAKRSA
                     EAGVKAAQAAIKSAGINLNRSRITAPISGFIGQSKVSEGTLLNAGDTTVLATIRQTNP
                     MYVNVTQSASEVMKLRRQIAEGKLLAADGVIAVGIKFDDGTVYPEKGRLLFADPTVNE
                     STGQITLRAAVPNDQNILMPGLYVRVLMDQVAVDNAFVVPQQAVTRGAKDTVMIVNAQ
                     GGMEPREVTVAQQQGTNWIVTSGLKDGDKVVVEGISIAGITGAKKVTPKEWAPSESQA
                     SAPQSGVQTASEAKTASEAE"
     gene            1307..4510
                     /gene="mtrD"
                     /locus_tag="ACFOAE_001672"
     CDS             1307..4510
                     /gene="mtrD"
                     /locus_tag="ACFOAE_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MtrD"
                     /protein_id="HFC6885123.1"
                     /translation="MAKFFIDRPIFAWVISIFIIAAGIFGIKSLPVSQYPSVAAPTIT
                     LHATYPGASAQVMEDSVLSVIERNMNGVEGLDYLSTSADSSGSGSVSLTFTPDTDENL
                     AQVEVQNKLSEVLSTLPATVQQYGVTVSKARSNFLMIVMLSSDVQSTEEMNDYAQRNI
                     VPELQRIEGVGQVRLFGAQRAMRIWVDPKKLQNYNLSFADIGSALSAQNVQISAGSIG
                     SLPAVRGQTVTATVTAQGQLGTAEEFGNVILRANTDGSNVYLKDVARVGLGMEDYSSS
                     TRLNGVNTTGMAVMLSNSGNAMATAKAVKERMATLEKYFPQGMSWKTPYDTSKFVEIS
                     IEKVIHTLIEAMVLVFVVMYLFLQNIRYTLIPTIVVPISLLGGFAFISYMGMSINVLT
                     MFAMVLVIGIVVDDAIVVVENVERIMAGEGLPPKAATKKAMGQISGAVIGITAVLMSV
                     FVPLAMFSGATGNIYKQFALTMAASIAFSAFLALTLTPALCATMLKTIPKGHHEEKKG
                     FFGWFNKKFNSWTHGYEGRVAKVLRKTFRMMVVYIGLAVVGVFLFMRLPTSFLPTEDQ
                     GFVMVSVQLPAGATQERTNATLAQVTQLAKSIPEIENIITVSGFSFSGSGQNMAMGFA
                     ILKDWNERTAPGSDAVAIAGKLTGMMMGTLKDGFGIAVVPPPILELGNGSGLSINLQD
                     RNNTGHTALLAKRNELIQKMRASGLFDPSTVRAGGLEDSPQLKIDINRAAAAAQGISF
                     ADIRTALASALSSSYVSDFPNQGRLQRVMVQADEDARMQPADILNLTVPNKSGVAVPL
                     STIATVSWENGTEQSVRFNGYPSMKLSASPATGVSTGQAMAAVQKMVDELGGGYSFEW
                     GGQSREEAKGGSQTLILYGLAVAAVFLVLAALYESWSIPLAVILVIPLGLIGAAAGVT
                     GRNLFEGLLGSVPSFANDIYFQVGFVTVMGLSAKNAILIIEFAKDLQAQGKSAVEAAL
                     EAARLRFRPIIMTSFAFILGVVPLYIAGGASSASQRAIGTTVFWGMLIGTLLSVFLVP
                     LFYVVVRKFFKETAHEHEMAVKHAAEAGITGSDDSQH"
     gene            4565..5968
                     /gene="mtrE"
                     /locus_tag="ACFOAE_001673"
     CDS             4565..5968
                     /gene="mtrE"
                     /locus_tag="ACFOAE_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MtrE"
                     /protein_id="HFC6885124.1"
                     /translation="MDTTLKTTLTSVAAAFALSACTMIPQYEQPKVEVAETFKNDTAD
                     SGIRAVDLGWHDYFADPRLQKLIDIALERNTSLRTAVLNSEIYRKQYMIERNNLLPTL
                     AANANDSRQGSLSGGNVSSSYKVGLGAASYELDLFGRVRSSSEAALQGYFASTANRDA
                     AHLSLIATVAKAYFNERYAEEAMSLAQRVLKTREETYKLSELRYKAGVISAVALRQQE
                     ALIESAKADYAHAARSREQARNALATLINQPIPDDLPAGLPLDKQFFVEKLPAGLSSE
                     VLLDRPDIRAAEHALKQANANIGAARAAFFPSIRLTGSVGTRSAELGGLFKSGTGVWS
                     FAPSITLPIFTWGTNKANLDVAKLRQQAQIVAYESAVQSAFQDVANALAAREQLDKAY
                     DALSKQSRASKEALRLVGLRYKHGVSGALDLLDAERSSYSAEGAALSAQLTRAENLAD
                     LYKALGGGLKRDTQTDK"
     gene            complement(6160..6357)
                     /locus_tag="ACFOAE_001674"
                     /pseudo
     CDS             complement(6160..6357)
                     /locus_tag="ACFOAE_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003757319.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
     gene            complement(6357..6563)
                     /locus_tag="ACFOAE_001675"
                     /pseudo
     CDS             complement(6357..6563)
                     /locus_tag="ACFOAE_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009311098.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015129 - lactate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015727 - lactate transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
BASE COUNT         1577 a         1828 c         1959 g         1629 t
ORIGIN      
        1 gaatgcctgt tgattggcaa aaccctttac atcaaaccag acagatagga taaataatgg
       61 ctttttatgc ttttaaggcg atgcgtgcgg ccgcgttggc tgccgccgtt gcattggtac
      121 tgtcgtcttg cggtaaaggc ggagacgcgg cgcagggcgg gcagcctgct ggtcgggaag
      181 cccctgcgcc cgtcgtcggt gtcgtaaccg tccatccgca aaccgtcgcg ttgaccgtcg
      241 agttgccggg gcgtttggaa tcgctgcgta ccgccgatgt ccgcgcccaa gtcggcggca
      301 tcatccaaaa acgcctgttc caagaaggca gttatgtccg tgccggacag ccgctgtatc
      361 agatcgacag ttccacttat gaagcaaatc tggaaagcgc gcgcgcgcaa ctggcaacgg
      421 ctcaggcaac gcttgccaaa gcggatgcgg atttggcgcg atacaagcct ttggttgccg
      481 ccgaagccgt cagccggcag gaatacgatg ctgcggtaac ggcgaaacgt tctgccgagg
      541 caggtgtcaa agcagcacag gcggcgatca aatctgccgg catcaatctg aaccgttcgc
      601 gcattaccgc gccgatttcc ggctttatcg gtcagtccaa agtttccgaa ggtacgctgt
      661 tgaatgcggg cgatacgacc gtgctggcaa ccatccgcca aaccaatccg atgtatgtga
      721 acgttaccca gtctgcatcc gaagtgatga aattgcgccg tcagatagcc gaaggcaaac
      781 tgctggcggc ggatggtgtg attgcggtcg gcatcaaatt tgacgacggc acagtttacc
      841 ctgaaaaagg ccgcctgctg tttgccgatc cgaccgtcaa cgaatcgacc ggtcagatta
      901 ccctgcgcgc cgccgtaccg aacgatcaga atatcctgat gcccggcctg tatgtgcgcg
      961 tgctgatgga ccaagtggcg gtggataacg catttgttgt gccgcagcag gcggtaacgc
     1021 gcggtgcgaa agataccgtg atgattgtga atgcccaagg cggtatggaa ccccgcgagg
     1081 taacggttgc gcaacagcag ggtacgaatt ggattgttac gtcgggtctg aaggacgggg
     1141 acaaggtggt tgtggaaggc atcagtatcg ccggtataac gggtgcgaaa aaggtaacgc
     1201 ccaaagaatg ggcgccgtct gaaagccaag cctctgcgcc tcaatccggc gttcagacgg
     1261 catctgaagc caaaactgct tctgaagcgg aataaggaag gcatcgatgg ctaaattttt
     1321 tatcgaccgc cccattttcg cgtgggttat ttcgattttc attattgcgg cgggtatttt
     1381 cggcattaaa agcctgcctg tttcgcaata tccgtctgtc gccgccccga ccattacttt
     1441 gcacgccact tatccgggtg cgtccgcgca ggtaatggaa gacagcgtgc tttccgtgat
     1501 cgagcggaat atgaacggcg tggaaggttt ggattatctg tccacttccg ccgattcgag
     1561 cggcagcggc agcgtgagcc tgacctttac gcccgatacc gacgagaatc tggcgcaggt
     1621 ggaagtgcag aacaagcttt ccgaagtatt gagcacgctg ccggcaaccg tccagcaata
     1681 cggcgtaacc gtatccaagg cgcgttccaa tttcctgatg attgtgatgc tttcgtcgga
     1741 tgtgcagtca accgaagaga tgaacgacta cgcgcagcgt aatatcgttc ccgagttgca
     1801 gcgtatcgaa ggcgtggggc aggtacgcct gttcggcgcg caacgcgcga tgcggatttg
     1861 ggttgatcct aagaaactgc aaaactacaa tttgtcgttt gccgatatcg gcagtgcgct
     1921 gtccgcccag aacgtccaga tttcagcggg ttctatcggt tcgcttcccg ccgttcgcgg
     1981 acagacggtt acggctaccg taacggcgca agggcagttg ggtacggcag aagaattcgg
     2041 caacgtcatc ctccgcgcca ataccgacgg ttctaatgtt tacctgaagg atgtggcaag
     2101 ggtcggactg ggtatggaag actattcttc ctcaacccgt ctgaacggtg taaataccac
     2161 cggtatggcg gtgatgctgt ccaacagcgg caatgcgatg gcgacggcaa aggcggttaa
     2221 agaacgcatg gcgacgttgg aaaaatactt tcctcagggt atgagctgga aaacccctta
     2281 cgatacttcc aaattcgtcg aaatttcgat tgaaaaagtg attcacactt taatcgaagc
     2341 gatggtgctg gtgtttgtcg taatgtatct cttcctgcaa aacatccgtt atacgctgat
     2401 tccgaccatc gtcgtaccga tttccctgtt gggcggtttc gccttcatct cttatatggg
     2461 catgtcgatt aacgtactga ccatgtttgc gatggttttg gtcatcggta tcgtggtcga
     2521 tgacgcgatt gtggtggttg aaaacgtcga gcgcattatg gcgggcgaag gcctgccgcc
     2581 caaggcggca accaaaaaag caatgggtca gatttccggt gcggtcatcg gtattactgc
     2641 tgttttgatg tctgtattcg ttcctctggc tatgttcagc ggggcgacgg gcaatatcta
     2701 taaacagttt gcactgacta tggcggcatc gatagccttc tctgccttcc ttgcgctgac
     2761 actcacacct gctttgtgtg ccacaatgtt gaagaccatc ccgaaagggc atcacgaaga
     2821 gaaaaaaggt ttcttcggtt ggtttaacaa gaaattcaac agttggacgc acggttacga
     2881 aggccgggtt gccaaagtgc tgcgtaagac tttccgcatg atggttgtct atatcggctt
     2941 ggcggttgtg ggcgtgttcc tgtttatgcg cctgccgact tcgttcctgc cgaccgaaga
     3001 ccaaggcttc gtcatggtca gcgtgcaact gcctgcagga gcgacccaag agcgcaccaa
     3061 tgcgactttg gcgcaagtta cccaactggc gaaaagcatt cctgaaatag aaaacatcat
     3121 taccgtttcc ggcttcagct tttcgggcag cggtcagaat atggcgatgg gttttgccat
     3181 attgaaagat tggaacgagc gtaccgcgcc cggcagcgat gccgttgcga ttgccggcaa
     3241 gctgacgggt atgatgatgg ggacgcttaa agacggtttt ggcatcgccg tcgtcccgcc
     3301 tccgattctg gagttgggca atggttcggg cctgagcatc aacctgcaag accgcaataa
     3361 taccggccat accgcattgc tggcgaagcg caacgagttg attcagaaaa tgcgtgccag
     3421 cggtttgttt gaccccagca ccgtccgtgc cggcggtttg gaagactcgc cgcagttgaa
     3481 aatcgacatc aaccgtgccg cggcggcggc gcaaggcatt tcgtttgccg acatccgcac
     3541 cgcattggca agcgcgctga gttcgtctta tgtcagcgac ttcccgaacc aaggccgtct
     3601 gcaacgcgtg atggtgcagg ccgacgagga tgcccgtatg cagcctgccg atattttgaa
     3661 cctgaccgtg ccgaacaaat ccggcgtcgc cgtaccgctt tccaccattg ctactgtttc
     3721 ttgggaaaac ggtacggaac agagcgtacg cttcaacggt tatccttcga tgaagctgtc
     3781 cgcttcgcct gcaaccggcg tttccaccgg gcaggctatg gcggcggttc aaaaaatggt
     3841 tgacgaattg ggcggcggtt acagcttcga atggggcgga cagtcgcgcg aagaggcaaa
     3901 aggcggctcg caaaccctga ttttgtacgg tttggcggtt gcagccgtat ttttggtact
     3961 tgccgcgctt tatgaaagct ggtcgattcc gctggcggtc atccttgtga ttccgttggg
     4021 tttgatcggt gcggctgcgg gcgtaaccgg gcgcaacctg tttgaaggac tgttgggcag
     4081 cgttccctcg ttcgccaacg acatctactt tcaagtcggt ttcgttaccg tgatgggttt
     4141 gagtgcgaaa aacgcgattt tgattatcga gtttgccaaa gaccttcaag cgcaagggaa
     4201 aagcgcggtt gaagccgctt tggaagccgc ccgcctgcgt ttccgtccga ttatcatgac
     4261 ctcgttcgcc tttattttgg gcgtggttcc cctgtatatt gccggtggtg caagttctgc
     4321 cagccagcgc gccatcggca cgaccgtatt ctgggggatg ctcatcggca cgctcttgtc
     4381 cgtgttcctt gttccgcttt tctatgtggt ggtgcgcaaa ttcttcaaag aaaccgcgca
     4441 cgaacacgaa atggcagtaa aacacgccgc cgaagcgggc atcaccggtt cggacgacag
     4501 ccaacattaa gcaaccatgc cgtctgaacg cccacgggtt ttcagacggc atcaggactt
     4561 ttttatggat actacattga aaaccacctt gacttctgtt gcagcagcct tcgcattatc
     4621 cgcctgcacc atgattcccc aatacgagca gcccaaagtc gaagttgccg aaacgttcaa
     4681 aaacgatacc gccgacagcg gcatccgtgc ggtcgattta ggttggcatg actattttgc
     4741 cgacccgcgc ctgcaaaagc tgatcgacat cgcactcgag cgcaatacca gtttgcgtac
     4801 cgccgtattg aacagcgaaa tctaccgcaa acaatacatg attgagcgca acaacctcct
     4861 gcccacgctt gccgccaatg cgaacgactc gcgccaaggc agcttgagcg gcggcaatgt
     4921 aagcagcagc tacaaagtcg gactgggtgc ggcatcttac gaactcgatc tgttcgggcg
     4981 tgtacgcagc agcagcgagg cggcactgca aggctatttc gccagcaccg ccaaccgcga
     5041 tgcggcacat ttgagcctga ttgccaccgt tgccaaagcc tatttcaacg aacgttacgc
     5101 cgaagaagcg atgtctttgg cgcaacgtgt tttgaaaacg cgcgaggaaa cctacaagct
     5161 gtccgaatta cgttacaagg caggtgtgat ttccgccgtc gccctacgtc agcaggaagc
     5221 cctgatcgaa tctgccaaag ccgattatgc ccatgccgcg cgcagccgcg aacaggcgcg
     5281 caatgccttg gcaaccttga ttaaccaacc gatacccgac gacctgcccg ccggtttgcc
     5341 gctggacaag cagttttttg ttgaaaaact gccggccggt ttgagttccg aagtattgct
     5401 cgaccgtccc gatatccgtg ctgccgaaca cgcgctcaaa caggcaaacg ccaatatcgg
     5461 tgcggcacgc gccgcctttt tcccatccat ccgcctgacc ggaagcgtcg gtacgcgttc
     5521 tgccgaattg ggcgggctgt tcaaaagcgg cacgggcgtt tggtcgtttg cgccgtctat
     5581 taccctgccg atttttacct ggggtacgaa caaggcgaac cttgatgtag ccaagctgcg
     5641 ccaacaggca caaatcgttg cctatgaatc cgccgtccaa tccgcatttc aagacgtggc
     5701 aaacgcattg gcggcgcgcg agcagttgga taaagcctat gacgctttaa gcaaacaaag
     5761 ccgcgcctct aaagaagcgt tgcgtttggt cggtctgcgt tacaaacacg gcgtatccgg
     5821 cgcgctcgac ttgctcgatg cggaacgcag cagctattcg gcggaaggtg cggctttgtc
     5881 ggcacaactg acccgcgccg aaaaccttgc cgatttgtac aaggcactcg gcggcggatt
     5941 gaaacgggat acccaaaccg acaaataacc ggtcgggcaa taaaatgccg tctgaaacga
     6001 taaggtttca gacggcattt ctttctttat agtggattaa aaaaaaccag tacagcgttg
     6061 gctcgcctta gctcaaagag aacgattctc taaggtgctg aagcaccaag ttgtactatt
     6121 tgtactgtct gcggcttcgt cgccttgtcc tgatttttgt taatccacta tatgtttgac
     6181 ggttgcggtc aggctgcgcg gcgtgccgta aacgtgaatg tcgggcatag ggcggtagcg
     6241 tttgttgaac acgttttcaa agtccaaacc gatgcgggtg gatttgccga ttttgtaatg
     6301 cgcggtcaaa tccagcgtgg cgtaggggcg ttgggtcagt gcggctgcgg cggcagggaa
     6361 gaaaccgcca tacccgccgg catcccgaag ccgaatacgg caacggcaag cgcaatcagc
     6421 agcgtataaa gccccgcctg atagcctttc agcttcagga cggtcagcgc ggcaaagaaa
     6481 aagacgatgg gtaagagtgc ggcggcggca gtcagataca ggctgccgcc gattgccgtg
     6541 tagttttgaa cccaagtttc cataattgaa catctccgaa aatatttttc taatcgtcgg
     6601 caatagtggt caaaccaatt aaagcaacgt tgcattactt tgcgaaactt taatattcag
     6661 gtcaatagaa tggattaaat ttaaaccagt acggcgttgc ctcgccttac cgtactatct
     6721 gtactgtctg cggcttcgtc gccttgtcct gatttttgtt aatccactat atatttttgg
     6781 gcggttcggc agatttgaat cggagctttc gtttaaatcc tgtcaaaaca aatatttgta
     6841 taaacaaaaa ttgtagtttg gtgtagtttt ttcttgtgtt tcgggggcgg tgcgaggtaa
     6901 atgccgttga cggcgggaac ggcgtgtcat tagaatccgc cctgattggt cagtccaatt
     6961 tgatgtttga tgtatagtgg atgaacaaaa acc
//
LOCUS       DAXIDM010000098         6806 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000098 DAXIDM010000000
VERSION     DAXIDM010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6806
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.098"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(111..1457)
                     /gene="mnmE"
                     /locus_tag="ACFOAE_001676"
     CDS             complement(111..1457)
                     /gene="mnmE"
                     /locus_tag="ACFOAE_001676"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFC6885125.1"
                     /translation="MSDNVPTIAAVATAPGRGGVGVIRISGKNLLPMAEALCGKTPKP
                     RVATYADFTDADGQAIDSGLLLFFAAPASFTGEDVIELQGHGGPVVMDMLLNRCLELG
                     ARLAEPGEFTKRAFLNDKLDLAQAEGVADLIDASSRSAARLALRSLKGDFSRRIHGLV
                     EDLITLRMLVEATLDFPEEDIDFLEAADARGKLDGLRRAVDDVLANAQQGAILREGLN
                     VVLVGAPNVGKSSLLNALAGDEVAIVTDIAGTTRDAVRERILIDGVPVHIVDTAGLRE
                     TDDVVERIGIERSRKAVSEADVALVLVDPREGVNDKTRAILDALPPELKRIEIHSKSD
                     LHAHAAGGFGTGAETVIALSAKTGDGLDALKRTLLREAGWQGEGEGLFLARTRHVNAL
                     KAAQEELSLAALCGNHQIELFAEHLRLAQVACGEITGEFTADDLLGVIFSRFCIGK"
     gene            1588..1743
                     /locus_tag="ACFOAE_001677"
     CDS             1588..1743
                     /locus_tag="ACFOAE_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885126.1"
                     /translation="MEKRNTYALLLGIGSLLGLFHPAKTAIRPNPADDLKNIGGDFQR
                     AIEKARK"
     gene            1740..2171
                     /locus_tag="ACFOAE_001678"
     CDS             1740..2171
                     /locus_tag="ACFOAE_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2335 domain-containing protein"
                     /protein_id="HFC6885127.1"
                     /translation="MTENAQDKARQAVETVVKSPELVEQILSDEYVQIMIARRFHSGP
                     LPPPSDLAQYNDIISNGADRIMAMAEKEQAVRHETIRQDQTFNRRGQLYGFISVILIL
                     LFAVFLVWSGYPATAASLAGGTVVALAGAFVIGRSRDQGKN"
     gene            2305..6654
                     /gene="app"
                     /locus_tag="ACFOAE_001679"
     CDS             2305..6654
                     /gene="app"
                     /locus_tag="ACFOAE_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003713554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesion and penetration autotransporter App"
                     /protein_id="HFC6885128.1"
                     /translation="MKTTDKRTTETHRKAPKTGRIRFSPAYLAICLSFGILPQAWAGH
                     TYFGINYQYYRDFAENKGKFAVGAKDIEVYNKKGELVGKSMTKAPMIDFSVVSRNGVA
                     ALVGDQYIVSVAHNGGYNNVDFGAEGRNPDQHRFSYQIVKRNNYKPDNSHPYNGDYHM
                     PRLHKFVTDAEPVEMTSDMRGNTYSDKEKYPERVRIGSGHHYWRYDDDKHGDLSYSGA
                     WLIGGNTHMQGWGNNGVVSLSGDVRHANDYGPMPIAGAAGDSGSPMFIYDKTNNKWLL
                     NGVLQTGYPYSGRENGFQLIRKDWFYDDIYRGDTHTVFFEPRSNGHFSFTSNNNGTGT
                     VTETNEKVSNPKLKVQTVRLFDESLNETDKEPVYAAGGVNQYRPRLNNGENLSFIDYG
                     NGKLILSNNINQGAGGLYFEGDFTVSPENNETWQGAGVHISEDSTVTWKVNGVANDRL
                     SKIGKGTLHVQAKGENQGSISVGDGTVILDQQADDKGKKQAFSEIGLVSGRGTVQLNA
                     DNQFNPDKLYFGFRGGRLDLNGHSLSFHRIQNTDEGAMIVNHNATTTSTVTITGNESI
                     TQPSGKNINRLNYSKEIAYNGWFGEKDTTKTNGRLNLVYQPAAEDRTLLLSGGTNLNG
                     NITQTNGKLFFSGRPTPHAYNHLGSGWSKMEGIPQGEIVWDNDWINRTFKAENFHIQG
                     GQAVISRNVAKVEGDWHLSNHAQAVFGVAPHQSHTICTRSDWTGLTNCVEKTITDDKV
                     IASLTKTDISGNVSLADHAHLNLTGLATLNGNLSANGDTRYTVSHNATQNGNLSLVGN
                     AQATFNQATLNGNTSASGNASFNLSNNAAQNGSLTLSDNAKANVSHSALNGNVSLADK
                     AVFHFENSRFTGQLSGSKDTALHLKDSEWTLPSGTELGNLNLDNATITLNSAYRHDAA
                     GAQTGSVSDTPRRRSRRSLLSVTPPTSVESRFNTLTVNGKLNGQGIFRFMSELFGYRS
                     DKLKLAESSEGTYTLAVNNTGNEPVSLDQLTVVEGKDNKPLSENLNFTLQNEHVDAGA
                     WRYQLIRKDGEFRLHNPVKEQELSDKLGKAEAKKQAEKDNAQSLDALIAAGRDAAEKT
                     ESVAEPARQAGGENVGIMQAEEEKKRVQADKDSALAKQREAETRPATTAFPRARRARR
                     DLPQPQPQPQPQPQPQRDLISRYANSGLSEFSATLNSVFAVQDELDRVFAEDRRNAVW
                     TSGIRDTKHYRSQDFRAYRQQTDLRQIGMQKNLGSGRVGILFSHNRTENTFDDGIGNS
                     ARLAHGAVFGQYGIGRFDIGISTGAGFSSGSLSDGIGSKIRRRVLHYGIQARYRAGFG
                     GFGIEPHIGATRYFVQKADYRYENVNIATPGLAFNRYRAGIKADYSFKPAQHISITPY
                     LSLSYTDAASGKVRTRVNTAVLAQDFGKTRSAEWGVNAEIKGFTLSLHAAAAKGPQLE
                     AQHSAGIKLGYRW"
BASE COUNT         1796 a         1981 c         1679 g         1350 t
ORIGIN      
        1 gccttgtcct gatttttgtt aatccactat aaaaccaaac ggatcggatt cccgttttta
       61 tgggataacg gaatgttcag ccggacaccg ccacgatgct ttcgatccgt ttattttccg
      121 atacaaaacc tcgaaaaaat cacgccgagc aggtcgtccg ccgtaaactc gcccgtgatt
      181 tcgccgcatg cgacctgcgc caagcgcaag tgttcggcaa acagctcgat ttgatggttg
      241 ccgcacaatg ccgccagcga caattcttcc tgcgctgctt tgagtgcgtt gacgtgccgc
      301 gtccgcgcca aaaacagccc ttcgccctcg ccctgccatc cggcctcgcg caacaacgtc
      361 cgtttcagcg cgtccaagcc gtcgccggtt ttcgccgaca gcgcgatgac ggtttccgcg
      421 cccgtaccga acccgcctgc cgcgtgtgcg tgcaaatcgg atttgctgtg gatttcgatg
      481 cgtttcaact ccggcggcaa cgcgtccaaa atcgcccgtg tcttgtcgtt cacgccttcg
      541 cgcggatcga ccaacaccag cgcgacatcg gcttcggata cggctttgcg gctgcgttcg
      601 atgccgatgc gttcgaccac gtcgtccgtc tcgcgcaaac ctgccgtatc gacaatatgc
      661 accggaacgc cgtcaatcag gatacgttcc ctgaccgcgt cgcgcgtcgt tccggcaata
      721 tcggtaacaa tcgccacttc gtcgcccgcc agcgcgttca acaggctgga tttgccgaca
      781 ttcggcgcgc cgaccaatac gacattcaga ccttcgcgca aaatcgcgcc ctgctgcgcg
      841 ttggcaagca catcatccac ggcgcggcgc aagccgtcca gtttgccgcg tgcgtctgcc
      901 gcttcgagaa aatcaatgtc ttcctcggga aaatctaacg tcgcttcgac cagcatccgc
      961 aaggtaatca agtcttcgac cagaccgtgt atccgccgcg aaaaatcgcc tttgagcgag
     1021 cgcaacgcca gacgcgccgc cgaacggctg gatgcgtcaa tcaaatccgc cacgccttcc
     1081 gcctgtgcca agtccagttt gtcgtttaaa aacgcacgct tcgtaaactc gcccggttcg
     1141 gcaaggcgcg cgcccaattc caaacagcgg ttcagcagca tatccatcac taccggcccg
     1201 ccgtgtccct gaagctcgat aacatcttcg cccgtaaaac ttgccggtgc ggcaaaaaaa
     1261 agcaaaagcc cgctgtcgat tgcctgaccg tccgcgtccg taaaatcagc ataggttgcc
     1321 acgcgcggct tgggcgtttt cccacacaaa gcctctgcca tcggcagcag gtttttcccc
     1381 gatatgcgta tcacgcccac gccgccgcgc ccgggtgcgg tagcgactgc cgcaatcgtt
     1441 ggaacgttat ccgacataaa acccccgaaa attcaaaaca gccgcgatta tagcaaatgc
     1501 cgtctgaagt ccgacggttt ggctttcaga cggtataaaa ccgcaaaaat gcttgataaa
     1561 tccgtccgcc tgacctaata taaccatatg gaaaaacgaa acacatacgc cctcctgctc
     1621 ggtataggct cgctgttggg cctgttccat cccgcaaaaa ccgccatccg ccccaatccc
     1681 gccgacgatc tcaaaaacat cggcggcgat tttcaacgcg ccatagagaa agcgcgaaaa
     1741 tgaccgaaaa cgcacaggac aaggcgcggc aggctgtcga aaccgtcgtc aaatccccgg
     1801 agcttgtcga gcaaatcctg tccgacgagt acgtgcaaat aatgatagcc cggcgtttcc
     1861 attcgggacc gttgccgccg ccgtccgact tggcgcaata caacgacatt atcagcaacg
     1921 gggcagaccg cattatggca atggcggaaa aagaacaagc cgtccggcac gaaaccatac
     1981 ggcaagacca aaccttcaac aggcgcgggc aactgtacgg cttcatcagc gtcatcctga
     2041 tactgctttt tgccgtcttc ctcgtatgga gcggctaccc cgcaaccgcc gcctcccttg
     2101 ccggcggcac agtggttgcc ttggcgggtg ctttcgtgat tggaagaagc cgagaccaag
     2161 gcaaaaatta atgacaaatc ctagggcgtg cttcatatcc gcccgaacgc cgaaccgcac
     2221 atataggcac atcccgcgcg ccgcccggaa gcggaagccg cgccctccca aacaaacccg
     2281 aatcccgtca gataaggaaa aataatgaaa acaaccgaca aacggacaac cgaaacacac
     2341 cgcaaagccc cgaaaaccgg ccgcatccgc ttctcgcctg cttacttagc catatgcctg
     2401 tcgttcggca ttcttcccca agcctgggcg ggacacactt atttcggcat caactaccaa
     2461 tactatcgcg actttgccga aaataaaggc aagtttgcag tcggggcgaa agatattgag
     2521 gtttacaaca aaaaagggga gttggtcggc aaatcaatga caaaagcccc gatgattgat
     2581 ttttctgtgg tgtcgcgtaa cggcgtggcg gcattggtgg gcgatcaata tattgtgagc
     2641 gtggcacata acggcggcta taacaacgtt gattttggtg cggaaggaag aaatcccgat
     2701 cagcaccgtt tttcttacca aattgtgaaa agaaataatt ataagcctga caattcacac
     2761 ccttacaacg gcgattacca tatgccgcgt ttgcataaat ttgtcacaga tgcagaacct
     2821 gtcgaaatga cgagtgacat gagggggaat acctattccg ataaagaaaa atatcccgag
     2881 cgtgtccgca tcggctcagg acaccactat tggcgttatg atgatgacaa acacggcgat
     2941 ttatcctact ccggcgcatg gttaattggc ggcaatacac atatgcaggg ttggggaaat
     3001 aatggcgtag ttagtttgag cggcgatgtg cgccatgcca acgactatgg ccctatgccg
     3061 attgcaggtg cggcaggcga cagcggttcg ccaatgttta tttatgacaa aacaaacaat
     3121 aaatggctgc tcaacggagt tttacaaacc ggctaccctt attccggcag ggaaaacggt
     3181 ttccagctga tacgcaaaga ttggttctac gatgacattt acagaggcga tacacatacc
     3241 gtcttttttg aaccgcgcag taacggacat ttttccttta catccaacaa caacggtacg
     3301 ggtacggtaa cagaaaccaa cgaaaaggtt tccaatccaa agcttaaagt acagacagtc
     3361 cgactgtttg acgaatcttt gaatgaaact gataaagaac cagtttacgc ggcagggggt
     3421 gttaatcagt accgtccaag gttaaacaac ggtgaaaacc tttcttttat cgattacggc
     3481 aacggcaaac tcatcttatc aaacaacatc aaccaaggcg cgggcggttt gtattttgaa
     3541 ggtgatttta cggtctcgcc tgaaaacaac gaaacgtggc aaggcgcggg cgttcatatc
     3601 agtgaagaca gtaccgttac ttggaaagta aacggcgtgg caaacgaccg cctgtccaaa
     3661 atcggcaaag gcacgctgca cgttcaagcc aaaggggaaa accaaggctc gatcagcgtg
     3721 ggcgacggta cagtcatttt ggatcagcag gcagacgata aaggcaaaaa acaagccttt
     3781 agtgaaatcg gcttggtcag cggcaggggt acggtgcaac tgaatgccga taatcagttc
     3841 aaccccgaca aactctattt cggctttcgc ggcggacgtt tggatttaaa cgggcattcg
     3901 ctttcgttcc accgtattca aaataccgat gaaggggcga tgattgtcaa tcataatgcc
     3961 acaacaacat ccaccgttac cattacaggg aatgaaagta ttacacaacc gagtggtaag
     4021 aatatcaata gacttaatta cagcaaagaa attgcctaca acggttggtt tggcgagaaa
     4081 gatacgacca aaacgaacgg gcggctcaac cttgtttacc agcccgccgc agaagaccgc
     4141 accctgctgc tttccggcgg aacaaattta aacggcaaca tcacgcaaac aaacggcaaa
     4201 ctgtttttca gcggcagacc gacaccgcac gcctacaatc atttaggaag cgggtggtca
     4261 aaaatggaag gtatcccaca aggagaaatc gtgtgggaca acgactggat caaccgcacg
     4321 tttaaagcgg aaaatttcca tattcagggc gggcaggcgg tgatttcccg caatgttgcc
     4381 aaagtggaag gcgattggca tttgagcaat cacgcccaag cagtttttgg tgtcgcaccg
     4441 catcaaagcc atacaatctg tacacgttcg gactggacgg gtctgacaaa ttgtgtcgaa
     4501 aaaaccatta ccgacgataa agtgattgct tcattgacta agaccgacat cagcggcaat
     4561 gtcagccttg ccgatcacgc tcatttaaat ctcacagggc ttgccacact caacggcaat
     4621 cttagtgcaa atggcgatac acgttataca gtcagccaca acgccaccca aaacggcaac
     4681 cttagcctcg tgggcaatgc ccaagcaaca tttaatcaag ccacattaaa cggcaacaca
     4741 tcggcttcgg gcaatgcttc atttaatcta agcaacaacg ccgcacaaaa cggcagtctg
     4801 acgctttccg acaacgctaa ggcaaacgta agccattccg cactcaacgg caatgtctcc
     4861 ctagccgata aggcagtatt ccattttgaa aacagccgct ttaccggaca actcagcggc
     4921 agcaaggata cagcattaca cttaaaagac agcgaatgga cgctgccgtc aggcacggaa
     4981 ttaggcaatt taaaccttga caacgccacc attacactca attccgccta tcgccacgat
     5041 gctgcaggcg cgcaaaccgg cagtgtgtca gacacgccgc gccgccgttc gcgccgttcc
     5101 ctattatccg ttacaccgcc aacttcggta gaatcccgtt tcaacacgct gacggtaaac
     5161 ggcaaattga acggtcaagg aatattccgc tttatgtcgg aactcttcgg ctaccgaagc
     5221 gacaaattga agctggcgga aagttccgaa ggcacttaca ccttggcggt caacaatacc
     5281 ggcaacgaac ccgtaagcct cgatcaattg acggtagtgg aagggaaaga caacaaaccg
     5341 ctgtccgaaa accttaattt caccctgcaa aacgaacacg tcgatgccgg cgcgtggcgt
     5401 taccaactca tccgcaaaga cggcgagttc cgcctgcata atccggtcaa agaacaagag
     5461 ctttccgaca aactcggcaa ggcagaagcc aaaaaacagg cggaaaaaga caacgcgcaa
     5521 agccttgacg cgctgattgc ggccgggcgc gatgccgccg aaaagacaga aagcgttgcc
     5581 gaaccggccc ggcaggcagg cggggaaaat gtcggcatta tgcaggcgga ggaagagaaa
     5641 aaacgggtgc aggcggataa agacagcgcc ttggcgaaac agcgcgaagc ggaaacccgg
     5701 ccggctacca ccgccttccc ccgcgcccgc cgcgcccgcc gggatttgcc gcaaccgcag
     5761 ccccaaccgc aacctcaacc ccaaccgcag cgcgacctga tcagccgtta tgccaatagc
     5821 ggtttgagtg aattttccgc cacgctcaac agcgttttcg ccgtacagga cgaattggac
     5881 cgcgtgtttg ccgaagaccg ccgcaacgcc gtttggacaa gcggcatccg ggacaccaaa
     5941 cactaccgtt cgcaagattt ccgcgcctac cgccaacaaa ccgacctgcg ccaaatcggt
     6001 atgcagaaaa acctcggcag cgggcgcgtc ggcatcctgt tttcgcacaa ccggaccgaa
     6061 aacaccttcg acgacggcat cggcaactcg gcacggcttg cccacggcgc cgttttcggg
     6121 caatacggca tcggcaggtt cgacatcggc atcagcacgg gcgcgggttt tagcagcggc
     6181 agtctttcag acggcatcgg aagcaaaatc cgccgccgcg tgctgcatta cggcattcag
     6241 gcacgatacc gcgccggttt cggcggattc ggcatcgaac cgcacatcgg cgcaacgcgc
     6301 tatttcgtcc aaaaagcgga ttaccgctac gaaaacgtca atatcgccac ccccggcctt
     6361 gcgttcaacc gctaccgcgc gggcattaag gcagattatt cattcaaacc ggcgcaacac
     6421 atttccatca cgccttattt gagcctgtcc tataccgatg ccgcttcggg caaagtccga
     6481 acacgcgtca ataccgccgt attggctcag gatttcggca aaacccgcag tgcggaatgg
     6541 ggcgtaaacg ccgaaatcaa aggtttcacg ctgtccctcc acgctgccgc cgccaaaggc
     6601 ccgcaactgg aagcgcaaca cagcgcgggc atcaaattag gctaccgctg gtaacaccgg
     6661 atatgccgaa aggggtttga cgatgccgcc gtgcgctgtc aaaccctttt tctgccgccg
     6721 ccttgtgcct gctccattgt ctgataaccg tcaaattgat ttttagccca tgtttggtgg
     6781 gtcggggaaa tctatatctt cgtccg
//
LOCUS       DAXIDM010000099         6593 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000099 DAXIDM010000000
VERSION     DAXIDM010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6593
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.099"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(731..1777)
                     /gene="recA"
                     /locus_tag="ACFOAE_001680"
     CDS             complement(731..1777)
                     /gene="recA"
                     /locus_tag="ACFOAE_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFC6885129.1"
                     /translation="MSDDKSKALAAALAQIEKSFGKGAIMKMDGSQQEENLEVISTGS
                     LGLDLALGVGGLPRGRIVEIFGPESSGKTTLCLEAVAQCQKNGGVCAFVDAEHAFDPV
                     YARKLGVKVEELYLSQPDTGEQALEICDTLVRSGGIDMVVVDSVAALVPKAEIEGDMG
                     DSHVGLQARLMSQALRKLTGHIKKTNTLVVFINQIRMKIGVMFGSPETTTGGNALKFY
                     SSVRLDIRRTGSIKKGEEVLGNETRVKVIKNKVAPPFRQAEFDILYGEGISWEGELID
                     IGVKNDIINKSGAWYSYNGAKIGQGKDNVRVWLKENPEVANEIDAKIRALNGVEMHIT
                     EGTQDETDGERPEE"
     gene            2031..2795
                     /gene="aroD"
                     /locus_tag="ACFOAE_001681"
     CDS             2031..2795
                     /gene="aroD"
                     /locus_tag="ACFOAE_001681"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFC6885130.1"
                     /translation="MCSCLVVKNTVIGSGRTKIAVPLVARDAAELSAVLEQIKNMPFD
                     IAEFRADFLECAGSIGEILHHTQTVRDALPDKPLLFTFRRHGEGGSFPCSDDYYFELL
                     DALIESRLPDIIDIELFSGETAVRCAVANAQKNGIAALLCNHEFHRTPPQEEIVCRLK
                     QMEDCGADICKIAVMPQSAEDVLTLLSATLKAKELAAKPIVTMSMGQTGAVSRLAGQV
                     FGSSITFGSGTQNSAPGQIGVSALRATLDCLENGAD"
     gene            2815..4830
                     /gene="rep"
                     /locus_tag="ACFOAE_001682"
     CDS             2815..4830
                     /gene="rep"
                     /locus_tag="ACFOAE_001682"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HFC6885131.1"
                     /translation="MMKLNPQQLEAVRYLGGPLLVLAGAGSGKTGVITQKIKHLIVNV
                     GYLPHTVAAITFTNKAAAEMQERVAKMLPKSQTRGLTICTFHSLGMKILREEANHIGY
                     KKNFSILDSTDSAKIIGELLGGTGKEAVFKAQHQISLWKNDLKTPEDVVQTASNIWEQ
                     QTARVYASYQETLQSYQAVDFDDLIRLPAVLLQQNSEVRNKWQRRLRYLLVDECQDTN
                     TCQFTLMKLLTGAEGMFTAVGDDDQSIYAWRGANMENLRKMQENYPQMKVIKLEQNYR
                     STARILKIANKVIENNPKLFTKKLWSKLGEGEPVKVVACQNEQHEADWVVSQIVKQKL
                     IGGDKTQYADFAVLYRGKHQARIFEEALRGARIPYRLSGGQSFFDKAEIKDVLSYVRL
                     LANPNDDPAFLRAVTTPKRGIGDVTLGKLNTYAHEHECSLYEAAQNEEALATLNNTNR
                     QHLQAFMDMFGSYRAKAETGEAGELINNLLEEIDYKNHLMQNEEGKAGEIKWRNVGDL
                     VSWFARKGGEDGKNIIELAQTIALMTLLEGKSEEEVDAVKLSTLHASKGLEYPYVFLV
                     GCEEGVLPHNDSIEEGNVEEERRLMYVGITRAKRQLTLTHCIKRKKQGIWQFPEPSRF
                     IDEMPQEDLKILGRKGGEPIVSKEEGRRNLADIIGRLDSMKKGGPAD"
     gene            complement(4898..5956)
                     /gene="dinB"
                     /locus_tag="ACFOAE_001683"
     CDS             complement(4898..5956)
                     /gene="dinB"
                     /locus_tag="ACFOAE_001683"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFC6885132.1"
                     /translation="MSSRKIIHIDMDAFYASVELREQPHLKGRPVVVAWEGARSVICA
                     ASYEARQFGLHSAMSVATAKRLCPQAVYVPPHFDLYRQVSAQIHAVFRRYTDLIEPLS
                     LDEAYLDVTRNFKNIPYASEVAKEIRAAIFAETGLTASAGIAPNKFLAKIASDWRKPN
                     GQFVLPPHKVMAFLETLPLGKIPGVGKVTLKKMQSLGMRTAGDLRRFERGELLNHFGR
                     YGYRLYDLVRGTDERPVKAERERLQISTEITLPEDLPLEQAAGHLPHLAEDLWRQITR
                     KNVEAQSVTLKLKTYDFRIITRTLTYSSVLPDCAALLQAAQMLMARVPPQTEDAFRLI
                     GIGVGHLVPKNQQQDLWA"
     gene            complement(6099..6506)
                     /locus_tag="ACFOAE_001684"
                     /pseudo
     CDS             complement(6099..6506)
                     /locus_tag="ACFOAE_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212999.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fe(3+)-pyochelin receptor"
BASE COUNT         1563 a         1794 c         1770 g         1466 t
ORIGIN      
        1 catccgtacc gcttaaatgc cgtctgaaat ttcgtcattc ccatgaaaac gggaatccag
       61 ccccgtggga gcagaaactt acaccccgtc attcccgcga acgcgggaat ccagtaaccg
      121 aaaaaccaca ggaatctatc ggaaaaaaca gaaacccccg accgtcattc ccgcaaaagc
      181 gggaatccag taaccgaaaa accacgggaa tctatcggaa aaaacagaaa cccccgaccg
      241 tcattcccgc gaacgcggga atctagaacg tagaatctga gaaaccgttt tactcgataa
      301 atttccgtgc cgaggggtct ggattcccgc gttcgcggga atgacggcat attttttgca
      361 tttgatataa agggtcgttt gaattttgtt cagcaagtgc aaagtgttgc acataaaagg
      421 gcgcaggata gaggcaaagc gggcgtaggt cgggctgtag caactgtatt tttcaccccg
      481 tcgggcaaaa atatagtgga ttaacaaaaa ccagtacggc gttgcctcgc cttagctcaa
      541 agagaacgat tctctaaggt actgaagcac caagtgaatc ggttccgtac tatctgtact
      601 gtctgcggct tcgtcgcctt gtcctgattt ttgttaatcc actataccaa aactcaaatc
      661 aagccgttcg gaggcggctc aaaaaaacgg tacttcgcag cagaagtacc gtttatcggg
      721 atttcaggtt ttattcttcg gggcgttcgc cgtcggtttc gtcctgcgtc ccttcggtga
      781 tgtgcatttc tacgccgttg agggcgcgga tttttgcgtc gatttcattg gcgacttcgg
      841 gattttcctt cagccagacg cggacgttgt ctttgccctg accgattttc gcgccgttgt
      901 agctgtacca cgcgccggat ttgttgatga tgtcgttttt cacgccgatg tcgatcaatt
      961 cgccttccca actgatgcct tctccgtaga ggatgtcaaa ctctgcctga cggaacgggg
     1021 gggcgacttt gtttttgatg actttgacgc gggtttcgtt gcccaatacc tcttcgcctt
     1081 ttttgatgga tccggtgcgg cggatgtcga ggcggacgga agaatagaat ttcagcgcgt
     1141 tgccgccggt ggtggtttcg gggctgccga acattacgcc gatcttcatc cggatttggt
     1201 tgatgaacac aaccagcgtg ttggtttttt tgatgtgtcc ggtcagtttg cgcaaagcct
     1261 ggctcatcag gcgcgcctgc agtccgacat ggctgtcccc catatcgcct tcgatttcgg
     1321 ctttggggac gagtgcggct acggaatcga cgactaccat atctatgccg cccgaacgga
     1381 cgagtgtgtc gcagatttcc aaagcctgtt cgccggtatc gggctgggac aggtaaagct
     1441 cttcgacttt tacgccgagt ttgcgggcgt aaacgggatc gaaggcgtgt tcggcatcga
     1501 caaaggcgca cacgccgccg tttttctggc attgggcgac ggcttcgagg cagagggtgg
     1561 ttttgccgga ggattctggg ccgaagattt cgacgatgcg cccgcgcggc agaccgccga
     1621 ctccgagggc gaggtctaat ccgagcgatc cggtggaaat gacttcgagg ttttcttcct
     1681 gctggctgcc gtccattttc atgatggcgc ctttgccgaa acttttttcg atttgcgcca
     1741 gtgcggcggc aagtgctttg cttttgtcgt ctgacattgg ggttactccg gaacaaatgc
     1801 ggtatgtggg atgcggcgca acacgggctg cggcgcggga tgtgtatcgt tttcccgatg
     1861 tgcgggctat cggtaatgct gcttcacgag gttgccatta tcgcatattt ccttgcttgc
     1921 cgatatgcgc caggacgcgg cggcttgtgc cggaatggaa tctggatgcc gtctaaaagg
     1981 cggccggctt tgttataatg gcggctgttt tttctgtgtg tgcctgtttt atgtgttcct
     2041 gccttgttgt caaaaatacc gttatcggaa gcggacgcac caaaatcgcc gtgccgcttg
     2101 tcgcccgcga tgccgccgaa ctttccgccg tacttgagca aatcaaaaat atgcccttcg
     2161 atattgcgga gttccgcgcc gactttttgg aatgcgcggg cagtatcggc gaaatattgc
     2221 accacacgca gaccgtccgc gacgcgctgc ccgacaagcc gctgctgttt acgttcagac
     2281 ggcatggcga aggcggctcg ttcccgtgtt cggacgatta ttattttgaa ctgctcgacg
     2341 cgctgatcga aagccgcctg cccgacatca tcgacatcga gctgttttcc ggcgaaaccg
     2401 ccgtccggtg cgccgtggca aatgctcaaa aaaacggcat cgccgccctg ctctgcaatc
     2461 atgagtttca ccgcacgccg ccgcaagaag aaatcgtatg ccgtctgaaa cagatggagg
     2521 actgcggcgc ggacatctgc aaaattgcgg tgatgccgca aagcgcggaa gatgtgctga
     2581 ctttgctttc cgccacgctc aaagcgaaag agcttgccgc caaaccgatt gttacgatgt
     2641 cgatggggca gacgggggcg gtcagccggc ttgccggaca ggtgttcggc tcaagcatca
     2701 cgttcggttc gggaacgcaa aactccgcgc cggggcaaat cggcgtatcc gccctccgtg
     2761 cgacactcga ctgcctcgaa aacggcgcag actgatttca gacagcatca aaacatgatg
     2821 aaactcaatc cccaacagct cgaagccgtc cgctacctcg gcggcccact gctcgtcctt
     2881 gccggtgcag gcagcggcaa aaccggcgtg attactcaaa aaattaagca tttgattgtc
     2941 aatgtcggct acctgccgca taccgttgcc gcaattacct ttaccaacaa agccgccgcg
     3001 gaaatgcagg agcgcgtcgc caaaatgctg cccaagtcgc aaacgcgcgg gctgacaatt
     3061 tgcacgttcc attctttggg catgaagatt ttgcgcgaag aggcgaacca tatcggttac
     3121 aaaaaaaact tctccattct cgattctacc gacagcgcga aaatcatcgg cgaactctta
     3181 ggcggtacgg gcaaagaagc cgtattcaag gcgcagcacc agatttcctt gtggaaaaac
     3241 gatttaaaaa cgcctgaaga tgtcgttcag acggcatcga acatttggga acaacaaacc
     3301 gcacgcgtgt atgcgagcta tcaggaaacc ttacaaagct atcaggcagt ggacttcgac
     3361 gacttgatcc gcctgcctgc cgtgctgttg cagcaaaaca gcgaagtgcg caacaaatgg
     3421 cagcggcggc tgcgttatct gctggttgac gaatgccaag atacgaatac ctgccaattt
     3481 acgttgatga aacttctgac cggcgcggaa ggtatgttta ccgccgtcgg cgacgacgac
     3541 cagtccatct acgcatggcg cggcgcgaac atggaaaacc tgcgcaaaat gcaggaaaac
     3601 tatccgcaga tgaaggtcat caaactggag caaaactacc gctccaccgc gcggattctc
     3661 aaaatcgcca acaaagtcat cgagaacaac cccaagctgt tcaccaaaaa actttggtcg
     3721 aaattgggcg aaggcgagcc cgtcaaagtc gttgcctgcc aaaacgagca gcacgaagcc
     3781 gactgggtcg tcagccaaat cgtcaaacaa aaactcatcg gcggcgacaa aacccaatat
     3841 gccgatttcg ccgtgttgta ccggggaaag catcaggcga ggattttcga ggaagcattg
     3901 cgcggcgcgc gcatccccta ccgtctctcc ggcggacaaa gctttttcga caaagccgaa
     3961 atcaaagacg tgttgtctta tgtgcggctg cttgccaacc ccaacgacga tcccgccttt
     4021 ctgcgtgccg ttaccacgcc caaacgcggc atcggcgatg taacgctggg caagctcaac
     4081 acttacgcgc acgaacacga atgcagcctg tatgaagccg cgcaaaacga agaagccctc
     4141 gccacgctga acaataccaa ccgccaacac ctgcaagcct ttatggatat gttcggcagt
     4201 taccgtgcca aagccgaaac cggcgaagcg ggcgaactca tcaacaacct gctcgaagaa
     4261 atcgactata aaaaccattt gatgcaaaac gaagaaggca aagccggcga aatcaaatgg
     4321 cgcaacgtcg gcgatttggt atcatggttt gcgcgaaaag gcggggaaga cggcaaaaac
     4381 atcatcgagc ttgcccaaac catcgccctg atgacgcttt tagagggtaa aagcgaagaa
     4441 gaagtcgatg ccgtcaaact ctccaccctg cacgcttcca aaggtttgga atacccctac
     4501 gttttccttg tcggttgcga agaaggtgtt ttgccgcaca acgacagcat cgaagaaggc
     4561 aacgtcgaag aagaacgccg cctgatgtac gtcggcatca cccgcgccaa acgccaactc
     4621 acgctgaccc actgcatcaa acgcaaaaaa caaggcatat ggcagttccc cgaacccagc
     4681 cgattcatag acgaaatgcc gcaggaagat ttgaaaatcc tggggcgcaa aggcggcgaa
     4741 ccgattgtca gcaaagaaga aggcagacgc aaccttgccg atataatcgg aaggctcgac
     4801 agcatgaaaa aaggcggtcc ggcggattaa accggagccg caatgccgtc tgaaggcttc
     4861 agacggcata ttttttggac ggcgcgcgta aagcggttta cgcccacaaa tcctgctgct
     4921 ggtttttcgg cacaagatgc cccacgccga taccgataag gcggaacgcg tcttccgtct
     4981 gcggcgggac gcgcgccatc aacatttgcg cagcctgcag cagagctgcg cagtcgggca
     5041 atacggagga ataagtcagt gtgcgcgtga tgatgcggaa atcgtaggtc ttcagcttga
     5101 gcgttacgct ttgggcttcg acgtttttgc gcgtgatttg ccgccacaag tcttcggcaa
     5161 gatgggggag gtgtccggca gcctgctcga gcggcaggtc ttcgggcagg gtaatttctg
     5221 tggagatttg gaggcgttcg cgttcggctt tgacggggcg ttcgtccgta ccgcgcacca
     5281 aatcatagag gcggtatccg tagcgtccga aatggtttaa gagttcgccg cgctcgaaac
     5341 ggcgcaagtc gcccgccgtc cgcataccca gcgactgcat ttttttcagc gttaccttgc
     5401 ccacgccggg gattttgccc aaaggcaggg tttccaaaaa tgccatgact ttgtgcggcg
     5461 gcaacacaaa ctgcccgttc ggcttgcgcc agtccgacgc gattttcgcc agaaatttgt
     5521 tcggcgcgat gcctgcggat gcagtcaaac ctgtttccgc aaaaatggcg gcacggattt
     5581 ctttggcaac ttcactggcg taagggatgt ttttgaaatt acgggtaacg tcaagatagg
     5641 cttcgtccag cgacaagggt tcgattaaat cggtataacg cctgaatacg gcgtgaatct
     5701 gcgcggaaac ctgacggtac aaatcgaaat gcggcggcac atacaccgct tgcggacaca
     5761 gccttttcgc cgttgccacc gacatcgcgg aatgcagccc gaactgccgt gcctcatacg
     5821 atgcggcgca aatcaccgaa cgcgcgccct cccacgcgac gaccaccggc cgccctttca
     5881 aatgcggctg ttcgcgcagc tctaccgatg cgtagaacgc gtccatgtcg atgtggatga
     5941 ttttgcgtga agacatcggc tctgctgaag ataaaaagga tattctactg ccggcatcga
     6001 gcaaattcca aatatacgcc ccgataggcc tgcctccata aaaatgccgt ctgaaacata
     6061 ccctgttcag acggcatccg caaaactacg gttttcaatt aaaactgcca atccagtttc
     6121 atgctgacag tgcgcggctc tccatagaag ttgtttgcgc cgcgcgtacg gttgtagttg
     6181 ttctcaaaat aagtgcgtcc gtttaagttc gtaccgatga ggctcaattt ggcgtgtttg
     6241 cccaattcgt aacggacgaa accgtctatc agcccgtagc cgccctgcct gatgttgtac
     6301 aggctgcttg tgctgctttg tgcggacacg ccgccgccga cggtcagccc cgtattcggt
     6361 atatggaaac tcgttccgaa acggaatata tgcacgggtg tgaaattgct gaagttgtac
     6421 gggtctgcac tggaattttt ggcaaggcgt tcggcgttga cttcggctgc attcctatac
     6481 ctgctcttgt tgtaggtata acctgagacc tttgcaaaat tccccaaaat cccctaaatt
     6541 cccaccaagc catttagggg atttctcatg agcaccttct ttcaacaaac cgc
//
LOCUS       DAXIDM010000100         6566 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000100 DAXIDM010000000
VERSION     DAXIDM010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6566
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.100"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            285..2132
                     /locus_tag="ACFOAE_001685"
     CDS             285..2132
                     /locus_tag="ACFOAE_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex family protein"
                     /protein_id="HFC6885133.1"
                     /translation="MHDTRTMMIKPTALLLPALFFFPHAYAPAADLSENKAAGFALFK
                     NKSPDTESVKLKPKFPVRIDTQDSEIKDMVEEHLPLITQQQEEVLDKEQTGFLAEEAP
                     DNVKTMLRSKGYFSSKVSLTEKDGAYTVHITPGPRTKIANVGVAILGDILSDGNLAEY
                     YRNALENWQQPVGSDFDQDSWENSKTSVLGAVTRKGYPLAKLGNTRAAVNPDTATVDL
                     NVVVDSGRPIAFGDFEITGTQRYPEQIVSGLARFQPGTPYDLDLLLDFQQALEQNGHY
                     SGASVQADFDRLQGDRVPVKVSVTEVKRHKLETGIRLDSEYGLGGKIAYDYYNLFNKG
                     YIGSVVWDMDKYETTLAAGISQPRNYRGNYWTSNVSYNRSTTQNLEKRAFSGGIWYVR
                     DRAGIDARLGAEFLAEGRKIPGSDVDLGNSHATMLTASWKRQLLNNVLHPENGHYLDG
                     KIGTTLGAFLSSTALIRTSARAGYFFTPENKKLGTFIIRGQAGYTLARDNADVPSGLM
                     FRSGGASSVRGYELDSIGLAGPNGSVLPERALLVGSLEYQLPFTRTLSGAVFHDMGDA
                     AANFKRMKLKHGSGLGVRWFSPLAPFSFDIAYGHSDKKIRWHISLGTRF"
     gene            2187..6356
                     /locus_tag="ACFOAE_001686"
     CDS             2187..6356
                     /locus_tag="ACFOAE_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translocation/assembly module TamB
                     domain-containing protein"
                     /protein_id="HFC6885134.1"
                     /translation="MTDTAPTDTDPTENGTRKMPSEYRPTPPAKKRRPLLKLSAALLS
                     VLILAVCFLGWLAGTESGLRFGLYQIPSWFGVNISSQNLKGTLLDGFDGDNWSIETEG
                     ADLKISRFRFAWKPSELMRRSLHITEISAGDIAIVTKPTPPKEERPPLSLPDSIDLPA
                     AVYLDRFETGKISMGKAFDKQTVYLERLDASYRYDRKGHRLDLKAADTPWSSSSGSAS
                     VGLKKPFALDTAIYTKGGLEGKTIHSTARLSGSLKDVRAELAIDGGNIRLSGKSVIHP
                     FAESLDKTLEEVLVKGFNINPSAFVPSLPDAGLNFDLTAIPSFSDGIALEGSLDLENT
                     KAGFADRNGIPVRQVLGSFVIRQDGTVHIGNTSVALLGRGGIRLSGKIDTGKDILDLN
                     IGINSVGAEDVLQTAFKGRLDGSIGIGGTTASPKISWQLGIGTARTDGSLAIASDPAN
                     GQRKLVLDTVNIAAGQGSLTAQGYLELFKDRLLKLDIRSRAFDPSRIDPQLPAGNING
                     SINLAGELAKEKFTGKMRFLPGTFNGVPIAGSADIVYESRHLPRAAVDLRLGRNIIKT
                     DGGFGKKGDRLNLNITAPDLSRFGFGLAGSLNVRGHLSGDLDGGIRTFETDLSGAARN
                     LHIGKAADIRSLDFTLKGSPDTSRPIRADIKGSRLSLSGGAAVVDTADLMLDGTGVQH
                     RIRTHAAMTLDGKPFKFDLDASGGINRELTRWKGSIGILDIGGAFNLKLQNRMTLEAG
                     AERVAASAANWQAMGGSLNLQHFSWDKKTGISAKGGAHGLHIAELHNFFKPPFEHNLV
                     LNGDWDVAYGRNARGYLNISRQSGDAVLPGGQALGLNAFSLKTRFQNDRIGILLDGGA
                     RFGRINADLDIGNAFGGNMANAPLGGRITASLPDLGTLKPFLPAAAQNITGSLNAAAQ
                     IGGRVGSPSVNAAVNGSSNYGKINGNITVGQSNSFSTSPLGGKLNLTVADAEVFRNFL
                     PVGQTVKGSLNAAVTLGGSIADPHLGGSINGDKLYYRNQTQGIILDNGSLRSHIAGRK
                     WVIDSLKFRHEGTAELSGTVGMENSGPDVDIGAVFDKYRILSRPNRRLTVSGNTRLRY
                     SPQKGISVTGMIKTDQGLFGSQKSSMPSVGDDVVVLGEVKKEAAAPLPVNMNLTLDLN
                     DGIRFAGYGADVTIGGKLTLTAQSGGSVRGVGTVRVIKGRYKAYGQDLDITKGTVSFV
                     GPLNDPNLNIRAERRLSPVGAGVEILGSLNSPRITLTANEPMSEKDKLSWLILNRAGS
                     GSSGDNAALSAAAGALLAGQINDRIGLVDDLGFTSKRSRNAQTGELNPAEQVLTVGKQ
                     LTGKLYIGYEYSISSAEQSVKLIYRLTRAIQAVARIGSRSSGGELTYTIRFDRFSGSD
                     KKDSAGNSKGK"
BASE COUNT         1552 a         2104 c         1721 g         1189 t
ORIGIN      
        1 aaggttgcgt tgatttaccc tatgcagtgc cggacaggct ttgcttgatc attcggcgca
       61 acggtttaat ttattgaacg aaaataaatt tatttaatcc tgcctatttt ccggcactat
      121 tccgaaacgc agcctgtttt ccatatgcgg attagaaaca aaatacctta aaacaagcag
      181 atacatttcc ggcgggccgc aacctccgaa ataccggcgg cagtatgccg tctgaagcgt
      241 cccgccccgt ccgaacagtg ttaaaatcga aatccgccac accgatgcac gacacccgta
      301 ccatgatgat caaaccgacc gccctgctcc tgccggcttt atttttcttt ccgcacgcat
      361 acgcgcctgc cgccgacctt tccgaaaaca aggcggcggg tttcgcattg ttcaaaaaca
      421 aaagccccga caccgaatca gttaaattaa aacccaaatt ccccgtccgc atcgacacgc
      481 aggatagtga aatcaaagat atggtcgaag aacacctgcc gctcatcacg cagcagcagg
      541 aagaagtatt ggacaaggaa cagacgggct tcctcgccga agaagcaccg gacaacgtta
      601 aaaccatgct ccgcagcaaa ggctatttca gcagcaaagt cagcctgacg gaaaaagacg
      661 gagcttatac ggtacacatc acaccgggcc cgcgcaccaa aatcgccaac gtcggtgtcg
      721 ccatcctcgg cgacatcctt tcagacggca acctcgccga atactaccgc aacgcgctgg
      781 aaaactggca gcagccggta ggcagtgatt tcgatcagga cagttgggaa aacagcaaaa
      841 cttccgtcct cggcgcggta acgcgcaaag gctacccgct tgccaagctc ggcaacaccc
      901 gggcggccgt caaccccgat accgccaccg tcgatttgaa cgtcgtcgtg gacagcggcc
      961 gccccatcgc cttcggcgac tttgaaatca ccggcacaca gcgttacccc gaacaaatcg
     1021 tctccggcct ggcgcgcttc caaccgggca cgccctacga cctcgacctg ctgctcgact
     1081 tccaacaggc actcgaacaa aacgggcatt attccggcgc gtccgtacaa gccgacttcg
     1141 accgtctcca aggcgaccgc gtccccgtca aagtcagcgt aaccgaggtc aaacgccaca
     1201 agctcgaaac cggcatccgc ctcgattcgg aatacggttt gggcggcaaa atcgcctacg
     1261 actattacaa cctcttcaac aaaggctata tcggctcggt cgtctgggat atggacaaat
     1321 acgaaaccac gcttgccgcc ggcatcagcc agccgcgcaa ctatcggggc aactactgga
     1381 caagcaacgt ttcctacaac cgttcgacca cccaaaacct cgaaaaacgc gccttctccg
     1441 gcggcatctg gtatgtgcgc gaccgcgcgg gcatcgatgc caggctgggg gcagagtttc
     1501 tcgcagaagg ccggaaaatc cccggctcgg atgtcgattt gggcaacagc cacgccacga
     1561 tgctgaccgc ctcttggaaa cgccagctgc tcaacaacgt gctgcatccc gaaaacggcc
     1621 attacctcga cggcaaaatc ggtacgactt tgggcgcatt cctgtcctcc accgcgctga
     1681 tccgcacctc tgcccgcgca ggttatttct tcacgcccga aaacaaaaaa ctcggcacgt
     1741 tcatcatacg cggacaagcg ggttacaccc ttgcccgcga caatgccgat gtcccctcgg
     1801 ggctgatgtt ccgcagcggt ggcgcgtctt ccgtgcgcgg ttacgaactc gacagcatcg
     1861 gacttgccgg cccgaacgga tcggtcctgc ccgaacgcgc cctcttggtg ggcagcctgg
     1921 aataccaact gccgtttacg cgcacccttt ccggcgcggt attccacgat atgggcgatg
     1981 ccgccgccaa tttcaaacgt atgaagctga aacacggttc gggactgggc gtgcgctggt
     2041 tcagcccgct tgcgccgttt tccttcgaca tcgcctacgg gcacagcgat aagaaaatcc
     2101 gctggcacat cagcttggga acgcgcttct aaaccgatac ggccgcttca gacggcattg
     2161 cagcaaacca ttttgaaaca gacattatga ccgataccgc accgacagat accgatccga
     2221 ccgaaaacgg cacgcgcaaa atgccgtctg aataccgccc caccccgccg gcaaaaaaac
     2281 gccgcccgct gctgaagctg tcggcggcac tgctgtctgt cctgattttg gcagtatgtt
     2341 tcctcggctg gctcgccggt acggaatccg gtttgcgctt cgggctgtac caaatcccgt
     2401 cttggttcgg cgtaaacatt tcctcccaaa acctcaaagg cacgctgctc gacggcttcg
     2461 acggcgacaa ctggtcgata gaaaccgagg gggcagacct taaaatcagc cgcttccgct
     2521 tcgcgtggaa accgtccgaa ctgatgcgcc gcagcctgca cattaccgaa atttccgccg
     2581 gcgacatcgc catcgttacc aaaccgactc cgcctaaaga agaacgcccg ccgctcagcc
     2641 ttcccgacag catagacctg cctgccgccg tctatctcga ccgcttcgag acgggcaaaa
     2701 tcagcatggg caaagccttt gacaaacaaa ccgtctatct cgaacggctg gatgcttcat
     2761 accgttacga ccgcaaagga caccgccttg acctgaaggc cgccgacacg ccgtggagca
     2821 gttcgtcggg gtcagcctcg gtcggcttga aaaaaccgtt tgccctcgat accgccattt
     2881 acaccaaagg cggactcgaa ggcaaaacca tacacagtac ggctcggctg agcggcagcc
     2941 tgaaggatgt gcgcgccgaa ctggcgatcg acggcggcaa tatccgcctc tcgggaaaat
     3001 ccgtcatcca cccgtttgcc gaatcattgg ataaaacatt ggaagaagta ctggtcaaag
     3061 ggttcaacat caatccgtcc gccttcgtgc cttccctgcc cgatgccggg ctgaatttcg
     3121 acctgaccgc catcccgtcg ttttcagacg gcatcgcgct ggaaggctcg ctcgatttgg
     3181 aaaacaccaa agccggcttt gccgaccgca acggcatccc cgtccgtcag gttttaggca
     3241 gctttgtcat ccggcaggac ggcacggtgc atatcggcaa tacgtccgtc gccctgctcg
     3301 gacggggcgg catcaggctg tcgggcaaaa tcgacaccgg aaaagacatc ctcgatttaa
     3361 atataggcat caactccgtc ggcgcggaag acgtactgca aaccgcgttc aaaggcaggt
     3421 tggacggcag catcggcatc ggtggcacga ccgcctcgcc caaaatctct tggcaactcg
     3481 gcatcggcac ggcgcgcacg gacggcagcc tcgccattgc aagcgacccc gcaaacggac
     3541 agcggaaact ggtgctcgac accgtcaaca tcgccgccgg gcaaggcagc ctgaccgcgc
     3601 aaggctatct cgagctgttt aaagaccgcc tgctcaagct ggacatccgt tcccgcgcat
     3661 tcgacccttc gcgcatcgat ccacaacttc cggcaggcaa tatcaacggc tcaataaacc
     3721 ttgccggcga actggcaaaa gaaaaattca caggcaaaat gcggttttta cccggcacgt
     3781 tcaacggcgt accgattgcc ggcagtgccg acattgttta cgagtcccgc caccttccgc
     3841 gtgccgccgt cgatttgcgg ctggggcgga acattattaa aacagacggc ggcttcggca
     3901 aaaaaggcga ccggcttaac ctcaatatca ccgcacccga tttatcccgt ttcggtttcg
     3961 gactcgcggg gtctttaaat gtacgcggac acctttccgg cgatttggac ggtggcatcc
     4021 gaacctttga aaccgacctt tccggcgcgg cgcgcaacct gcacatcggc aaggcggcag
     4081 acatccgttc gctcgatttc acgctcaaag gttcgcccga cacaagccgc ccgatacgcg
     4141 ccgacatcaa aggcagccgc ctttcgctgt cgggcggagc ggcggttgtc gataccgccg
     4201 acctgatgct ggacggcacg ggcgtgcagc accgcatccg cacacacgcc gccatgacgc
     4261 tggatggcaa accgttcaaa ttcgatttgg acgcttcagg cggcatcaac agggaactta
     4321 cccgatggaa aggcagcatc ggcatcctcg acatcggcgg cgcattcaac ctcaagctgc
     4381 aaaaccgtat gacgctcgaa gccggtgcgg aacgcgtggc ggcaagtgcg gcaaattggc
     4441 aggcaatggg cggcagcctc aacctgcaac acttttcttg ggataaaaaa accggcatat
     4501 cggcaaaagg cggcgcacac ggtctgcata tcgccgagtt gcacaatttc ttcaaaccgc
     4561 ccttcgaaca caatctggtt ttaaacggcg actgggatgt cgcctacgga cgcaacgcgc
     4621 gcggctacct caatatcagc cggcaaagcg gcgatgccgt attgcccggc gggcaggctt
     4681 tgggtttgaa cgcattttcc ctgaaaacgc gctttcaaaa cgaccgcatc ggaatcctgc
     4741 ttgacggcgg cgcgcgtttc gggcggatta acgccgattt ggacatcggc aacgccttcg
     4801 gcggcaatat ggcaaatgca ccgctcggcg gcaggattac cgcctccctt cccgacttgg
     4861 gcacattgaa gccctttctg cccgccgccg cgcaaaacat taccggcagc ctgaatgccg
     4921 ccgcgcaaat cggcggacgg gtcggctctc cgtccgtcaa tgccgccgtc aacggcagca
     4981 gcaactacgg gaaaatcaac ggcaacatca ccgtcgggca aagtaattct ttcagtacct
     5041 cgcccctggg cgggaaactc aacctgaccg ttgccgatgc cgaagtattc cgcaacttcc
     5101 tgcccgtcgg acaaaccgtc aaaggcagcc tgaatgccgc cgtaaccctc ggcggcagca
     5161 tcgccgaccc gcacttgggc ggcagcatca acggcgacaa gctctattac cgcaaccaaa
     5221 cccaaggcat catcttggac aacggctcgc tgcgttcgca tatcgcgggc aggaaatggg
     5281 taatcgacag cctgaaattc cggcacgaag ggacggcgga actctccggt acggtcggta
     5341 tggaaaacag cggacccgat gtcgatatcg gcgcggtgtt cgacaaatac cgcatcctgt
     5401 cccgccccaa ccgccgcctg acggtttccg gcaacacccg cctgcgctat tcgccgcaaa
     5461 aaggcatatc cgttaccggg atgattaaaa cggatcaggg gctgttcggt tcgcaaaaat
     5521 cctcgatgcc gtccgtcggc gacgatgtcg tcgtattagg cgaagtcaaa aaagaggcgg
     5581 cggcaccgct ccccgtcaat atgaacctga ctttagacct caatgacggc atccgcttcg
     5641 ccggctacgg cgcggacgtt accataggcg gcaaactgac cctgaccgcc caatcgggcg
     5701 gaagcgtgcg gggcgtgggc acggtccgcg tcatcaaagg gcgttataag gcatacgggc
     5761 aggatttgga cattaccaaa ggcacggtct cctttgtcgg cccgctcaac gaccccaacc
     5821 tcaacatccg cgccgaacgc cgcctttccc ccgtcggtgc gggcgtggaa atattgggca
     5881 gcctcaacag tccgcgcatt acgctgacgg caaacgaacc gatgagtgaa aaagacaagc
     5941 tctcctggct catcctcaac cgcgccggca gcggcagcag cggcgacaat gccgccctgt
     6001 ccgcagccgc cggcgcgctg cttgccgggc aaatcaacga ccgcatcggg ctggtggatg
     6061 atttgggctt taccagcaag cgcagccgca acgcgcaaac cggcgaactc aaccccgccg
     6121 aacaggtgct gaccgtcggc aaacaactga ccggcaaact ctacatcggc tacgaataca
     6181 gcatctccag cgcggaacag tccgtcaaac tgatttaccg gctgacccgc gccatacagg
     6241 cggttgcccg tatcggcagc cgttcgtcgg gcggcgagct gacatacacc atacgtttcg
     6301 accgcttctc cggttcggac aaaaaagact ccgccggaaa cagcaaagga aaataagcgg
     6361 ttttcagacg gcgcgccgcc aaaccggaca tttgaaaacc tgcttttcca ccgtccgccg
     6421 ccgccgtccg cctgcaaggg aacagaatcg atatagtgaa ttaacaaaaa tcaggataag
     6481 gcgacgaagc cgcggacagt acaaatagta cggaaccgat tcactcggtg cttgagcacc
     6541 ttagagaatc gtttctttga gctaag
//
LOCUS       DAXIDM010000101         6542 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000101 DAXIDM010000000
VERSION     DAXIDM010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6542
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.101"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(47..313)
                     /locus_tag="ACFOAE_001687"
     CDS             complement(47..313)
                     /locus_tag="ACFOAE_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HFC6885135.1"
                     /translation="MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWMAWTR
                     HQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ"
     gene            complement(386..856)
                     /gene="rlmH"
                     /locus_tag="ACFOAE_001688"
     CDS             complement(386..856)
                     /gene="rlmH"
                     /locus_tag="ACFOAE_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFC6885136.1"
                     /translation="MNITVLAVGTKMPRWVDEAVAEYAKRFGRDVAYALKEIKPEKRG
                     AGVNAAQGMAAEEKRILEAVPQGAFLVVLDERGKAPTSVELAEHLKSWRQNGEHVCFV
                     IGGADGMTDRLKQQARMMMRLSSLTLPHGMVRVFLTEQLYRAVSILHNHPYHRE"
     gene            complement(910..1296)
                     /gene="rsfS"
                     /locus_tag="ACFOAE_001689"
     CDS             complement(910..1296)
                     /gene="rsfS"
                     /locus_tag="ACFOAE_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFC6885137.1"
                     /translation="MNEQELQDLQKMVGVAVNALEDIKAKDISVLETQDKTSLFARMI
                     IASGDSTRQVKALANNVAVDLKEAGFEILSTEGDSGEWTLVDAGDLVVHVMLPAVRDF
                     YDIDTLWGGEKPSFHAGMQKPWHAAD"
     gene            complement(1355..1948)
                     /gene="nadD"
                     /locus_tag="ACFOAE_001690"
     CDS             complement(1355..1948)
                     /gene="nadD"
                     /locus_tag="ACFOAE_001690"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFC6885138.1"
                     /translation="MKKIGLFGGTFDPIHNGHLHIARAFADEIGLDAVVFLPAGGPYH
                     KDAASASAADRLAMVELATAEDARFAVSDCDIVREGATYTFDTVQIFRQQFPSAQLWW
                     LMGSDSLMKLHTWKKWQMLVRETNIAVAMRQGDSLHQTPRELHAWLGKSLQDGSVRIL
                     SAPMHNVSSTEIRRAGVSDGIPPAAARYIREHGLYEK"
     gene            complement(1945..2544)
                     /locus_tag="ACFOAE_001691"
     CDS             complement(1945..2544)
                     /locus_tag="ACFOAE_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003690382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HFC6885139.1"
                     /translation="MSELDNILAHNRQFVESGEYEKYFTDKYPERGLAVLSCMDARII
                     GLLPDALGLKNGDAKLIKNAGALVTHPWGSVMRSLLVAVFELKVREIMVIAHHDCGMQ
                     GLNAEEFLGRVRESQIPEDRIETLRYAGIDLDGWLTGFDNVEDSVRHTVDLIRNHPLM
                     PRHIAVHGLVIHPVTGKLTLVVDGSVSDGMDLSEGMETS"
     gene            complement(2573..4114)
                     /locus_tag="ACFOAE_001692"
     CDS             complement(2573..4114)
                     /locus_tag="ACFOAE_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFC6885140.1"
                     /translation="MDGRRWAVWGAFALLPSAFLAAMVVAPLWAVAAYDGLAWRAVLS
                     DAYMLKRLAWTVFQAAATCVLVLPLGVPVAWVLARLAFPGRALVLRLLMLPFVMPTLV
                     AGVGVLALFGADGLLWRGRQDTPYLLLYGNVFFNLPVLVRAAYQGFVQVPAARLQTAR
                     TLGAGAWRRFLDIEMPVLRPWLAGGVCLVFLYCFSGFGLALLLGGSRYATVEVEIYQL
                     VMFELDMAVASVLVWLVLGVTAAAGLLYAWFGRRAVSDKAVSPVMPSPPQSVGEYVLL
                     AFAAAVLSVCCLFPLLAIVVKAWSAGESWRVLMESETWQAVWNTLRFSAAAVYAAAVL
                     GVVYAAAARRSAWMRGLMFLPFMVSPVCVSAGVLLLYPQWTASLPLLLAMYALLAYPF
                     VAKDVLSAWDALPPDYGRAAAGLGANGFQTACRITFPLLKPALRRGLTLAAATCVGEF
                     AATLFLSRPEWQTLTTLIYAYLGRAGEDNYARAMVLTLLLSAFALGIFLLLDNGEGGK
                     QTETL"
     gene            4505..5890
                     /locus_tag="ACFOAE_001693"
     CDS             4505..5890
                     /locus_tag="ACFOAE_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003705069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HFC6885141.1"
                     /translation="MDGWTQTLSAQTLLGISAAAIILILILIVKFRIHALLTLVIVSL
                     LTALATGLPTGSIVNDVLVKNFGGTLGGVALLVGLGAMLGRLVETSGGAQSLADALIR
                     MFGEKRAPFALGVASLIFGFPIFFDAGLIVMLPIVFATARRMKQDVLPFALASIGAFS
                     VMHVFLPPHPGPIAASEFYGANIGQVLILGLPTAFITWYFSGYMLGKVLGRTIHVPVP
                     ELLSGGTQDNDLPKEPAKAGTVVAIMLIPMLLIFLNTGVSALISEKLVSADETWVQTA
                     KIIGSTPIALLISVLVALFVLGRKRGESGSALEKTVDGALAPVCSVILITGAGGMFGG
                     VLRASGIGKALADSMADLGIPVLLGCFLVALALRIAQGSATVALTTAAALMAPAVAAA
                     GFTDWQLACIVLATAAGSVGCSHFNDSGFWLVGRLLDMDVPTTLKTWTVNQTLIALIG
                     FALSALLFAIV"
     gene            5910..6428
                     /locus_tag="ACFOAE_001694"
     CDS             5910..6428
                     /locus_tag="ACFOAE_001694"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase, GntK/IdnK-type"
                     /protein_id="HFC6885142.1"
                     /translation="MTTHFVVMGVCGCGKTTAALSLQKHLGQCPYAEGDEFHTQANRD
                     KMGAGIPLTDEDRYPWLGNLRDWMTKQAQNGADHTIVTCSALKRGYRDILRGAEGKAA
                     FIHLSPPQDINLERMMSRKGHYMKAGMLDSQLEILEELGEGEYGVKIANPGTPEAVEA
                     DILNWVASENLL"
BASE COUNT         1464 a         2021 c         1726 g         1331 t
ORIGIN      
        1 ccgtctgaag cagtttcgga cagcctgtgt tcaaaacgga aaaccgttat tgcggaacgt
       61 atccctgaac ggcatccgcg ccgtcgccga agaaatactg ctccatctgc tgagctaggt
      121 attcgcgcgc gcgcggatcg gcaaggctta agcggttttc gttaatcagc atcgtttggt
      181 ggcgcgtcca cgccatccat gcttcttgcg atacgttttc aaaaatgcgc ttgcccaatt
      241 cgttgggaag cggtggaaat ttcatgcctt cggcttcttt gttgagcttg acgcagaata
      301 ccatgcgtgc catagcggat tcctttgctg tgttcagaaa taacggggtg attttaaccg
      361 attagggata cggacaaaag ccttcttatt cccgatgata gggatggttg tgcaggatgg
      421 aaacggcgcg gtagagctgc tcggtcagaa agacgcgcac catgccgtgc ggcagggtga
      481 ggctggacag gcgcatcatc atgcgggctt gttgtttgag gcggtcggtc atgccgtccg
      541 cgccgccgat gacgaagcag acgtgttcgc cgttttgccg ccagcttttg aggtgttccg
      601 ccagctcgac ggaggtcggc gctttgccgc gttcgtcaag aacgacgagg aacgcgcctt
      661 gcggaacggc ttcgaggatg cgtttttctt ccgccgccat accttgggcg gcattcacgc
      721 ccgcgccgcg tttttcgggt ttgatttctt tgagtgcgta ggcgacgtcg cgtccgaagc
      781 gtttggcgta ttcggcgacg gcctcatcaa cccagcgcgg cattttggtg ccgactgcca
      841 aaacggtaat gttcaatgct ttctccctta caggaaaatg ccgtctgaac attcagacgg
      901 catcgggaat cagtctgccg cgtgccacgg cttctgcatt ccggcgtgaa aactcggttt
      961 ctcgccgccc caaagggtgt cgatatcata gaagtcgcgc acggcgggga gcataacgtg
     1021 gacgacgagg tctcctgcat caacgagcgt ccattcgccg ctgtctcctt cggtactgag
     1081 gatttcaaaa ccggcttctt tcaaatcgac ggcaacgttg ttggccagtg ctttgacttg
     1141 gcgcgtactg tcgccgctgg cgataatcat tctggcaaac agcgaagttt tgtcttgcgt
     1201 ttcgagaacg gaaatgtctt tggctttgat gtcttcgagg gcgttgacgg cgaccccgac
     1261 cattttttgc aggtcttgca gttcttgttc gttcattatt ttcctaacgg gatgttttca
     1321 gacggcatta tagccgtttc ttactgattt gactttattt ttcatacaaa ccgtgttcgc
     1381 ggatgtagcg tgcggcggca ggtgggatgc cgtctgaaac accggcgcgg cggatttccg
     1441 ttgacgacac attatgcatc ggggcggaca agatgcggac gctgccgtcc tgaagggact
     1501 tgcccagcca cgcgtgcagt tcgcgcgggg tttggtgcag gctgtcgccc tgccgcatgg
     1561 cgacggcgat attggtttcg cgcacgagca tctgccattt tttccatgtg tgcagcttca
     1621 tcaggctgtc gctgcccatc agccaccaga gttgcgcgga tgggaactgc tggcggaaga
     1681 tttggacggt atcaaaagta taggttgcac cttctcggac gatgtcgcaa tcgctgacgg
     1741 caaaacgcgc gtcttctgcc gtcgccagtt cgaccatggc aaggcggtcg gcggcggaag
     1801 cggaggctgc gtctttgtga tacgggccgc ctgccggcag gaaaacaacc gcgtccaagc
     1861 cgatttcgtc ggcaaaggcg cgggcgatgt ggagatgccc gttgtgtatc gggtcgaaag
     1921 tgccgccgaa cagtccgatt ttcttcatga tgtttccatt ccttccgata agtccatgcc
     1981 gtctgaaaca ctgccgtcca caaccagcgt cagtttgccg gtaacgggat ggatgaccag
     2041 tccgtgaacg gcgatatggc gcggcatcag cggatggtta cggataaggt ccaccgtgtg
     2101 gcgtacgctg tcttcgacgt tgtcgaaacc ggtcagccag ccgtcgaggt cgataccggc
     2161 ataacgcagg gtttcgatac ggtcttcggg aatctggctt tcccggacgc gcccgaggaa
     2221 ttcttcggca ttcagcccct gcataccgca atcgtgatgg gcgatgacca taatctctct
     2281 gaccttcaat tcaaacacgg caaccaaaag actccgcatc accgaacccc acgggtgcgt
     2341 aaccagcgcg ccggcatttt taatcagctt ggcatcgccg tttttcaaac ccaacgcgtc
     2401 gggcagcagc ccgataatcc gcgcatccat acaggacaaa actgccagcc cgcgttcggg
     2461 gtatttgtcg gtaaagtatt tttcatattc gcccgactcg acaaactgcc ggttatgggc
     2521 aaggatgtta tccaactcgc tcattttgcc gtcctctgaa aaagggttca cattataacg
     2581 tttccgtctg ttttccgcct tcgccgttgt ccaacagcag gaaaatgccc agcgcgaacg
     2641 ccgacaacag caatgtcaac accattgccc gcgcataatt atcctcaccc gcacgcccca
     2701 aataggcata aatcaaagtc gtcagcgtct gccactcggg acgcgacagg aacaaggttg
     2761 ccgcaaattc gcccacgcag gttgccgccg ccaaagtcag accgcgccgc aacgccggtt
     2821 tcaagagggg gaacgtgatg cggcatgccg tctgaaagcc gtttgcaccc aaacccgccg
     2881 ccgccctgcc gtaatccggc ggcagtgcat cccaggctga taaaacatct tttgccacaa
     2941 acggatacgc cagcagcgca tacatcgcca gcagcagcgg caacgaagcc gtccactgcg
     3001 gataaagcag cagcacgccc gccgaaacac aaaccggcga caccataaac ggcaaaaaca
     3061 tcagcccgcg catccacgcc gaccgccgcg ccgccgccgc atacaccaca cccaaaaccg
     3121 ccgccgcata caccgccgcc gccgagaagc gcaaagtatt ccacaccgcc tgccacgttt
     3181 cactttccat taacacacgc cacgattcgc cggccgacca cgctttcaca acaattgcca
     3241 acaaaggaaa caggcagcac acagacaaca ccgccgccgc aaacgccagc agcacatatt
     3301 ccccgaccga ctgcggcggc gacggcatca caggggaaac cgccttatcc gaaaccgcgc
     3361 gcctgccgaa ccacgcatac agcaaccctg ccgccgccgt tacccccaac accagccaca
     3421 ccagcaccga agcaaccgcc atatcgagtt cgaacatgac caactggtaa atttccactt
     3481 cgaccgtggc ataacggctg ccgcccagca gcaatgccag cccgaacccc gaaaaacaat
     3541 acaggaagac aaggcacacg ccgccggcaa gccacgggcg caaaacgggc atttcaatgt
     3601 ccaaaaaccg ccgccacgcc cccgcgccca acgtccgtgc cgtctgaagc cgtgccgcag
     3661 gcacttgcac aaacccctga tacgccgccc tgaccaacac aggaaggttg aaaaacacat
     3721 tgccgtacaa caacagatac ggcgtatcct gcctgccgcg ccacaacagc ccgtccgccc
     3781 cgaacagggc cagcacgccc acgcccgcca ccaacgtggg catcacaaaa ggcagcatca
     3841 gcaggcgcag caccaaagcc cgccccggaa acgccagccg cgccagcacc cacgcgacag
     3901 gcacgcccaa aggcagcacc agcacacagg ttgccgctgc ctgaaatacc gtccacgcca
     3961 aacgtttgag catataggca tccgacagca ccgcgcgcca cgccaaaccg tcatacgccg
     4021 ccaccgccca caaaggcgca acgaccattg ccgccaaaaa agccgaaggc agcagggcaa
     4081 aagcacccca taccgcccaa cgccgtccat ccatcgcctt ccccacttga aacactgatg
     4141 ttgcgattgt acccaaaagc cccacatacc gtatatttca atccgactac ataccgtatc
     4201 cgccttcctc ccgccgtctg aaatatagtg gattaacaaa aatcaggaca aggcaacgaa
     4261 gccgcagaca gtacagatag tacggaaccg attcacttgg tgcttcggca ccttagagaa
     4321 tcgttctctt tgagctaagg cgaggcaacg ccgtactggt ttttgttaat ccactataaa
     4381 tcgttcaaat aaacaggaat ataacttcag acaaacaact taccgcccga tttgtgctat
     4441 cgttttcgca caacttaaaa aacctgacaa ttttgtactt ttattacaga gaaaggcttt
     4501 acaaatggac ggctggacac agacgctgtc cgcgcaaacc ctgttgggca tttcggcggc
     4561 ggcaatcatc ctcattctga ttttaatcgt caaattccgc atccacgcgc tgctgacact
     4621 ggtcatcgtc agcctgctga cggctttggc aaccggtttg cccacaggca gcattgtcaa
     4681 cgacgtactg gtcaaaaact tcggcggcac gctcggcggc gtggcgcttc tggtcggcct
     4741 gggcgcgatg ctcggacgtc tggtcgaaac atccggcggc gcacagtcgc tggcggacgc
     4801 gctgatccgg atgttcggcg aaaaacgcgc accgttcgcg ctgggcgttg cctcgctgat
     4861 tttcggcttc ccgattttct tcgatgccgg actaatcgtc atgctgccca tcgtgttcgc
     4921 caccgcacgg cgcatgaaac aggacgtact gcccttcgcg cttgcctcca tcggcgcatt
     4981 ttccgtcatg cacgtcttcc tgccgcccca tccgggcccg attgccgctt ccgaatttta
     5041 cggcgcgaac atcggccaag ttttgatttt gggtctgccg accgccttca tcacatggta
     5101 tttcagcggc tatatgctcg gcaaagtgtt ggggcgcacc atccatgttc ccgttcccga
     5161 actgctcagc ggcggcacgc aagacaacga cctgccgaaa gaacctgcca aagcaggaac
     5221 ggtcgtcgcc atcatgctga ttcccatgct gctgattttc ctgaataccg gcgtatcggc
     5281 cctcatcagc gaaaaactcg taagtgcgga cgaaacctgg gttcagacgg caaaaataat
     5341 cggttcgaca ccgatcgccc ttctgatttc cgtattggtc gcactgtttg tcttgggacg
     5401 caaacgcggc gaaagcggca gcgcgttgga aaaaaccgtg gacggcgcac tcgcccccgt
     5461 ctgttccgtg attctgatta ccggcgcggg cggtatgttc ggcggcgttt tgcgcgcttc
     5521 cggcatcggc aaggcactcg ccgacagcat ggcggatttg ggcattcccg tccttttggg
     5581 ctgtttcctt gtcgccttgg cactgcgtat cgcgcaaggt tcggcaaccg tcgccctgac
     5641 caccgccgcc gcgctgatgg ctcctgccgt tgccgccgcc ggctttaccg actggcagct
     5701 cgcctgtatc gtattggcaa cggcggcagg ttcggtcggt tgcagccact tcaacgactc
     5761 cggcttctgg ctggtcggcc gcctcttgga catggacgta ccgaccacgc tgaaaacctg
     5821 gacggtcaac caaaccctca tcgcactcat cggctttgcc ttgtccgcac tgctgttcgc
     5881 catcgtctga cagacggaaa ggatagtaaa tgactacgca ttttgtcgtt atgggcgtat
     5941 gcggctgcgg caagaccacc gccgcgctgt ccctgcagaa acacctcggt caatgtccct
     6001 atgccgaagg cgacgagttc cacacccaag ccaaccgcga caagatgggc gcgggtattc
     6061 cgctgaccga tgaagaccgc tatccgtggt tgggcaatct gcgcgactgg atgacgaaac
     6121 aggcgcaaaa cggcgcggac cacaccatcg taacctgttc cgccctcaaa cgcggctacc
     6181 gcgacattct gcgcggagcc gaaggcaaag ctgccttcat ccacctcagt ccgccgcaag
     6241 acatcaacct cgagcgcatg atgtcgcgca aaggacatta catgaaagca gggatgctcg
     6301 attcgcaact ggaaatcctc gaggaactgg gcgaaggcga atacggggtc aaaatcgcca
     6361 accccggcac gcccgaagcg gtcgaagccg atattctgaa ctgggttgcc tcggaaaacc
     6421 tgctttgaag caatatgccg tctgaagccc gacacaggat gggtttcaga cggcataaac
     6481 atcgggaaca gaatggatta cattgattta tagtggatta acaaaaacca gtacagcgtt
     6541 gc
//
LOCUS       DAXIDM010000102         6480 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000102 DAXIDM010000000
VERSION     DAXIDM010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6480
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.102"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(67..1422)
                     /gene="xseA"
                     /locus_tag="ACFOAE_001695"
     CDS             complement(67..1422)
                     /gene="xseA"
                     /locus_tag="ACFOAE_001695"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFC6885143.1"
                     /translation="MSDFFHSDVLSVSELNAFAKSILENHLAGLWIAGEVSNLTRAAS
                     GHYYFSLKDSRAQVRCAMFKGAAARLAKPLKEGDHIEVSGKISIYEARGEFQITVNEV
                     RLKGLGQLYEAYERLKAQLQAEGAFAAERKKPLPARPQCIGIVTSLAAAALRDVVTTL
                     KRRAPEIPVIVYPTAVQGAGSEFQIAQAIKTASQRAECDVLIVCRGGGSIEDLWAFNE
                     EPVVRAIEACTVPVVSGVGHETDFTLADFVADVRAPTPTGAAELVSPNRQESLHRLAQ
                     AQGRLKTVLEQRYFDASQKLDWLARQIRHPRQKLDEQRTYIHKLAQTLSYSMTQNLRA
                     HAARFERQTQALQHYRPDISVYRQDIDRFQTTLSHAFHQLLTHRRQSLTAQAALLEAV
                     SPQHILERGFSVVKNTRGQVIRNADVLKQGQKLHIIFADGETDVRVSKEQGQQDLFDC
                     I"
     gene            1619..2440
                     /gene="nadE"
                     /locus_tag="ACFOAE_001696"
     CDS             1619..2440
                     /gene="nadE"
                     /locus_tag="ACFOAE_001696"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HFC6885144.1"
                     /translation="MMRIFSTGGKMDTQAVITHIARWLDEYAARANAKGFVVGVSGGI
                     DSAVVSALAARTGRPTLLLDMPIRQHPGQLERARLHIRNLQRQYANVSAQTVDLTDTF
                     QTFEQTVGAHQTAFDSQPLSLANARSRLRMLTLYYYGQIHGLLVTGTGNKIEDFGVGF
                     FTKYGDGGVDISPIADLTKTQVYRLAEALGVDEAIQKAPPTDGLWDTERTDEEQMGAS
                     YPELEWAMGVYGTRKPEDFEGRQREVLEIYTRLHRAMRHKINPIPVCRIPPELLG"
     gene            complement(2510..2994)
                     /gene="dnrN"
                     /locus_tag="ACFOAE_001697"
                     /pseudo
     CDS             complement(2510..2994)
                     /gene="dnrN"
                     /locus_tag="ACFOAE_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein DnrN"
     gene            3292..3624
                     /gene="trxA"
                     /locus_tag="ACFOAE_001698"
     CDS             3292..3624
                     /gene="trxA"
                     /locus_tag="ACFOAE_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA];
                     GO_process: GO:0006662 - glycerol ether metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HFC6885145.1"
                     /translation="MSSELIVHTSDAAFEKDVLNADIPVLLDFWAPWCGPCKMIAPIL
                     DDIAAEFEGRLKVVKINIDDNEATPSRFGVRGIPTLMVFKNGEVVATKVGALAKGQLT
                     AFVEASIA"
     gene            complement(3677..4624)
                     /locus_tag="ACFOAE_001699"
     CDS             complement(3677..4624)
                     /locus_tag="ACFOAE_001699"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFC6885146.1"
                     /translation="MTDITPFANRLGKNIKHLMKWVKRNGIEAWRIYDRDIPQFPFAA
                     DVYGDRIHLQEYDTGWLMRPEEYEAWLAEVLEAVAFVTGFAPEQIRLKRRERQKGLQQ
                     YEKTGKAGDDFVITENGRKFWVNLDKYLDTGLFLDHRNTRKKVGETAAGKRFLNLFSY
                     TGSFTVYAATGGAASSETVDLSNTYLDWARRNFELNGIDTERHKIVRADVFQYLQTAY
                     GEGRRFDLIVMDPPSFSNSKKMSDILDIQRDHKKLIDGAVKLLASDGILYFSNNLRSF
                     VLDDLVSEQYAVKDISKQSVPEDFRNKKIHRCWEIRHKS"
     gene            4952..6340
                     /locus_tag="ACFOAE_001700"
     CDS             4952..6340
                     /locus_tag="ACFOAE_001700"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFC6885147.1"
                     /translation="MSIKFADLNLDKNILSAVSSEGYESPTPIQAQAIPFALEGRDIM
                     ASAQTGSGKTAAFLLPTLQKLTKRSEKPGKGPRALVLTPTRELAAQVEKNALAYAKNM
                     RWFRTVSIVGGASFGYQTRALSKPVDLIVATPGRLMDLMQSGKVDFERLEVLILDEAD
                     RMLDMGFIDDIETIVEATPSDRQTLLFSATWDGAVGKLARKLTKDPEIIEVERVDDQG
                     KIEEQLLYCDDMRHKNRLLDHILRDANIDQCVIFTSTKAMTEVIADELYEKGFAANCL
                     HGDMPQGWRNRTLMDLRKGRCKILVATDVAARGIDVPTITHVINYDLPKQAEDYVHRI
                     GRTGRAGRTGIAITFAEVNEYVKVHKIEKYINRKLPELTIEGMEPTRKRKSAGGKPKG
                     KGGWGDRKSGGRRGDHKPGKEGFGGKTRGEGFKKEGFKKDGFKKTGEGFKGKRKAGDS
                     FAGRGERRYKDR"
BASE COUNT         1550 a         1760 c         1720 g         1450 t
ORIGIN      
        1 tcaagggact ggattcccgc tttcgcggga atgacggcgg agggggagcg gtttttccga
       61 ttgggtttaa atgcaatcga acaaatcctg ctgcccttgt tctttgctta cgcgcacgtc
      121 ggtttcgccg tcggcgaaga taatgtgcag cttctgcccc tgcttcaaaa catcggcgtt
      181 gcggatgact tgtccgcgtg tgtttttgac gacggaaaag ccgcgctcca gaatgtgctg
      241 cggcgaaacg gcttcgagca atgctgcttg ggcggtcagg ctttggcggc ggtgggtaag
      301 cagttggtgg aaggcgtgcg acaaggtcgt ctgaaagcgg tcgatgtctt gccggtaaac
      361 ggaaatatca ggacggtaat gttgcagggc ttgggtttgg cgttcgaaac gggcggcgtg
      421 ggcgcggagg ttttgcgtca tcgagtaaga cagcgtttgc gccagtttgt ggatgtaggt
      481 gcgctgttcg tcaagttttt ggcgcggatg acggatttgc cgtgcgagcc agtcgagttt
      541 ttggctggca tcgaaatagc gttgctccaa aacagttttc agacggcctt gcgcttgggc
      601 tagacgatgt aacgattctt ggcggttggg actgaccagc tccgccgcgc cggtcggcgt
      661 gggcgcgcgc acgtcggcga caaaatcggc aagcgtgaaa tcggtttcgt gacctacgcc
      721 gctgacgacg ggaaccgtgc aggcttcgat tgcgcgtacg accggttctt cgttaaacgc
      781 ccacaagtct tcaatgctgc cgccgccgcg acagacaatc aacacgtcgc attcggcgcg
      841 ttgcgatgcg gttttaatcg cttgggcaat ctgaaactcg ctgcccgcgc cctgaacggc
      901 agtcggataa acgatgacgg gaatttcggg cgcgcggcgt ttcaaggtgg ttacaacatc
      961 gcgcaatgcc gccgccgcca aactggttac gatgccgata cattgcggtc gggcaggcag
     1021 aggttttttg cgttccgccg caaacgcgcc ttccgcctgc aactgcgcct tcaaccgctc
     1081 ataggcttcg taaagctgcc ccaaaccttt gagccgtact tcgtttacgg taatttgaaa
     1141 ttcgccccgc gcctcgtaaa tactgatttt tcctgatacc tcgatatgat cgccttcttt
     1201 caaaggcttc gccaaacgcg ccgccgcacc tttgaacatc gcgcaacgca cctgcgcgcg
     1261 gctgtcttta agcgagaagt aataatgtcc gctggcggcg cgggtcaggt tggacacttc
     1321 gccggcaatc cacaaaccgg caaggtggtt ttccaaaata cttttggcaa atgcattcaa
     1381 ctcggaaacg gacaacacgt cagaatgaaa aaaatcagac atcgaatcaa tcaaataata
     1441 aaaaatatga atatgttttg aagcccaagg cggcatcggg ccgcctaaat tgtcaacaat
     1501 attataacac gcgccatctt gccgcccgcc ttttcccgta tgactttttt aagcggggaa
     1561 tgggaaaaat attcatcaac ctgcctgcaa tctattcaaa ttgcaccgcc ggcaggctat
     1621 gatgcggata ttttcgacag gaggaaaaat ggatacgcag gcagttatca cacatatcgc
     1681 ccgatggttg gacgaatacg ccgcccgggc aaatgcaaaa gggtttgtcg tgggcgtttc
     1741 cggcggcatc gattccgccg tcgtctccgc actcgccgcc cgcaccggcc gccccacgct
     1801 gcttctggat atgccgatac gccaacaccc cggccagctt gagcgggcaa ggctgcacat
     1861 ccgcaatctg caacggcaat atgccaatgt aagcgcgcaa acggtcgacc tgaccgacac
     1921 cttccagacc tttgaacaaa ccgtcggtgc tcatcagacg gcatttgaca gtcagccgct
     1981 ttccctcgcc aacgccagaa gccgcctacg tatgctgacc ctgtactact acgggcagat
     2041 acacggactg ctggttacgg ggacaggtaa taagattgaa gatttcggcg tgggcttttt
     2101 tactaaatac ggcgacggcg gcgtggacat cagcccgatt gccgacctga ccaaaacgca
     2161 ggtttaccgg cttgccgaag cattgggcgt ggacgaggcg attcaaaaag ccccgccgac
     2221 cgacggcctg tgggatacgg aacgcaccga cgaagaacag atgggcgcaa gctatcccga
     2281 actggagtgg gcaatgggcg tgtacggcac gcgcaaaccc gaagattttg aagggcggca
     2341 gcgcgaagtt ctagaaatct atacgcgact tcaccgcgcc atgcggcaca aaatcaaccc
     2401 gattcccgta tgccgcattc cgcccgaatt gctgggctga aacacggaaa tgccgtctga
     2461 aacggaaaac cgtatttcag acggcatgga aatatccgac tcctatccct taagaatcga
     2521 gtacgcgggc aaacaaaata tcgttttcca aatgaatgtg gtcgttcaaa tcctccacca
     2581 tttctttcgc cagcgcgtaa agccgcgtcc agcttccgca agccccttct ggcggttgga
     2641 aattgtcggt cagctctttg agccgtgcga tggcgcggtc gtgttcttcg tgttcgtgca
     2701 tcatcacgcc gatgggcatc gccgcaccgc gtccgacacc ctgattaatc atcggaaaca
     2761 gcatccgctc ctccttcatc atatgcatca gcagttcgtt ctgcatatag gcaagcagcc
     2821 cggcaatttc tgccggaaag gtaccggaaa ggtatcggca tggacttggg ccactttctg
     2881 cgccagcggc accaattctt caaattgtgc gcggtggaca ttgtggtagc gttgcaggat
     2941 atgatcgacg gttgcaccaa agggggcggt ctcccaaacg gaaaaatcag tcatcgcagt
     3001 gttcctttta cagggtttcg ggtttggttt tgaacattca tactttaaga atcaattcaa
     3061 acggagcata caccgcccgc gcgcttctgt acaacctcaa acgtattcct tacattttga
     3121 taataaaagt aattttcaga aataaaatac tgtccgaacc gttttttaga atttgcaaag
     3181 gcgattgggg cggtacagaa aaactattat cccgcccgcc cacttgaaat ttttatgccc
     3241 aagccctatc ctgcacgcta tcgtgccaat cccaaccgaa aaggaaaaat aatgagcagc
     3301 gaattgattg tacacaccag cgatgccgct tttgaaaaag acgttttaaa tgcagatatc
     3361 cccgtcctgc tggacttttg ggctccgtgg tgcggcccct gcaaaatgat tgccccgatt
     3421 ttggacgaca tcgccgccga atttgaaggc cgtctgaaag tggtcaaaat caacatcgac
     3481 gacaacgaag ccaccccgtc ccgtttcggc gtgcgcggca ttccgaccct gatggtgttc
     3541 aaaaacggcg aagtcgtcgc caccaaagtc ggcgcattgg caaaaggtca gctgaccgcc
     3601 tttgtcgaag cctctatcgc ctgataaagc gcaatcgaaa aagccgccgg aagattccgg
     3661 cggctttttc gcacccttaa gatttgtggc ggatttccca gcacctatgg atttttttgt
     3721 tgcggaaatc ttcgggaacg gattgtttgg aaatgtcttt gacggcgtat tgttccgata
     3781 ccaagtcgtc taagacgaag ctgcgcaggt tgttggaaaa gtacaaaatg ccgtctgaag
     3841 cgagcagctt caccgcgccg tcaatcagct ttttgtggtc gcgctggatg tcgaggatgt
     3901 cggacatttt cttgctgttg gaaaaactgg gcgggtccat cacaatgagg tcgaaccgcc
     3961 tgccttcccc atatgccgtc tgaagatatt ggaacacgtc ggcgcggacg attttatgcc
     4021 gttccgtatc gatgccgttc aattcaaaat tgcgtctcgc ccaatcaaga tatgtgttgg
     4081 acaaatcgac ggtttcgctg gatgccgcgc cgccggtggc ggcatagacg gtgaagctgc
     4141 cggtgtagga aaacaggttt aaaaaacgtt tgcccgccgc cgtttcgccg acttttttgc
     4201 gcgtgtttcg atgatccaaa aaaagccccg tatccaaata tttatcaagg ttgacccaaa
     4261 acttgcggcc gttttcggtg atgacgaaat cgtcgcccgc cttgccggtt ttctcgtact
     4321 gctgcaaacc tttttggcgt tcgcggcgtt tgaggcggat ttgttcgggc gcaaaaccgg
     4381 taacgaaagc gacggcttcc aagacttcgg caagccacgc ttcgtattct tcgggccgca
     4441 tcagccagcc ggtatcgtat tcctgaaggt ggattcgatc gccgtaaaca tcggcggcaa
     4501 aggggaattg ggggatgtcg cggtcgtaaa tgcgccaggc ttcgatgccg ttgcgtttca
     4561 cccatttcat aaggtgtttg atgtttttgc ccaagcggtt ggcaaacggt gtgatgtcgg
     4621 tcattggttt caggcggaat aaagtggaaa acggcaattt tactgtaatt aacgcccgat
     4681 tgcttgaccg tttcgggcaa accctatacc atccgtcgct tatcttgtca tacgaagcca
     4741 tcgccttcca acctaaaccg cccttacggg cgcgtttctt ctgttgcttt gattttgcaa
     4801 agcatatctg tgcaggttgc cgtcgatgta aaccacaagc aagccgcttg cgacaaccct
     4861 gtaacttcac attccccgta tcgttaccct tccctgcttc aggccgtctg aacctttcgg
     4921 acgcgggcgt tgttgtcttc caaggatagc catgtctatt aaatttgccg atttgaacct
     4981 tgataaaaac attttgtccg ccgtcagcag cgagggttac gaaagcccga cgccgattca
     5041 ggcgcaagcc attccgtttg ctttggaagg ccgcgacatc atggcttcgg cgcaaaccgg
     5101 ctccggcaaa accgccgcct ttctgttacc gactttgcaa aaactgacca aacgcagcga
     5161 aaaaccgggc aaaggcccgc gtgctttggt gttgaccccg acccgcgaac tggcggctca
     5221 agtcgagaaa aacgcgctgg cgtatgccaa aaatatgcgt tggttccgca ccgtcagcat
     5281 cgtcggcggc gcatcgttcg gctaccaaac ccgcgccctg agcaaaccgg tcgatctgat
     5341 tgtcgccacg ccgggccgtc tgatggactt gatgcaaagc ggcaaagtcg attttgaacg
     5401 tttggaagtg ctgattctgg acgaagccga ccgtatgttg gatatgggct ttatcgacga
     5461 catcgaaacc atcgtggaag caacgccgag cgaccgtcag actttattgt tctccgccac
     5521 ttgggacggc gcggtcggca aactggcacg caaactgacc aaagaccctg aaatcatcga
     5581 agtcgaacgc gtggacgacc aaggcaaaat cgaagaacaa ctgctgtact gcgacgatat
     5641 gcgccacaaa aaccgcctgc tcgaccacat cctgcgtgat gccaacatcg accaatgcgt
     5701 gattttcacg tccaccaaag ccatgaccga agtcatcgcg gatgaattgt acgaaaaagg
     5761 tttcgccgcc aactgcctgc acggcgacat gccgcagggc tggcgcaacc gcacgctgat
     5821 ggatttacgc aaaggccgct gcaaaatttt ggttgccacc gacgttgccg cacgcggtat
     5881 cgacgtaccg accattaccc acgtcatcaa ctacgacctg ccgaaacagg cggaagacta
     5941 cgtccaccgc atcgggcgca ccggccgcgc aggccgcacg ggtattgcga ttacgtttgc
     6001 cgaagtgaac gaatacgtca aagtccacaa aatcgaaaaa tacattaacc gcaaactgcc
     6061 cgaactgacc atcgaaggca tggaaccgac ccgcaaacgc aaatccgcag gcggtaagcc
     6121 aaaaggcaaa ggcggctggg gcgataggaa atccggcggc cggcgcggcg atcataaacc
     6181 gggcaaagaa ggcttcggcg gcaaaacgcg cggcgaaggt ttcaagaaag aaggctttaa
     6241 gaaagacggt ttcaaaaaaa ccggcgaagg cttcaaaggc aaacgtaaag ccggcgattc
     6301 ttttgcaggc agaggcgaac gccgttacaa agaccgctaa gccccaacct gcctcataaa
     6361 ccaatgccgt ctgaaaccga tttcgagttt cagacggcat ttttgcaatg tttcaacacc
     6421 gcccggcttt gatacccaaa ggattaatct gcaatatagt ggattaacaa aaaccagtac
//
LOCUS       DAXIDM010000103         6478 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000103 DAXIDM010000000
VERSION     DAXIDM010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6478
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.103"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(60..1094)
                     /gene="purM"
                     /locus_tag="ACFOAE_001701"
     CDS             complement(60..1094)
                     /gene="purM"
                     /locus_tag="ACFOAE_001701"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFC6885148.1"
                     /translation="MSTSLSYRDAGVDIDAGDQLVENIKPFAKRTMRPEVLGDLGGFG
                     ALVEIGKKYKNPVLVSGTDGVGTKLKLAFDWDKHDTVGIDLVAMSVNDILVQGAEPLF
                     FLDYFACGELDVPRATDVIKGIAQGCEESGCALIGGETAEMPGMYPVGEYDLAGFAVG
                     VVEKENVITGRSIGAGDVVLGLASNGAHSNGYSLIRKIIERDNPDLDAEFDNGKTLRE
                     AVIAPTRLYVKPILAALEKFTIKGMAHITGGGITENVPRVLPENTVAQIDAKSWELPK
                     LFQWLQKAGNVETQEMYRTFNCGIGMVVIVAAEDADAVQDLLGEQGETVYRLGLIRER
                     QGDEHQTQVA"
     gene            complement(1614..1698)
                     /locus_tag="ACFOAE_001702"
     tRNA            complement(1614..1698)
                     /locus_tag="ACFOAE_001702"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1662..1664),aa:Leu,seq:tag)
     gene            1852..2529
                     /locus_tag="ACFOAE_001703"
     CDS             1852..2529
                     /locus_tag="ACFOAE_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885149.1"
                     /translation="MPAALIKDFLLTQGLKLPLDEVRAAYLTAQTVMDMGTASIDRSV
                     LWRSDEDWKLADYLSCDNVREDALKRLFMALDSVFSRSTGVRSAAVYALMPSENQAFQ
                     LICLSRQGEVLENLWDLDEAAGKVSLACRSAQSGWMNVASDVRRWLDLGELSGERNHA
                     SAAQISIPVCTESGGVLGVVHVEFECAECAGTAAQVEWVALALALSEPLKLLLGMSAG
                     KDGSEDV"
     gene            2522..3115
                     /gene="ribA"
                     /locus_tag="ACFOAE_001704"
     CDS             2522..3115
                     /gene="ribA"
                     /locus_tag="ACFOAE_001704"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HFC6885150.1"
                     /translation="MSEMLNHVASCRLPTEWGVFTMHGFEEANGQEHVALTVGNFSDG
                     NPVLTRIHSECLTGDALFSRKCDCGPQLEAAMRAVQTEGRGIIVYLRQEGRGIGLINK
                     IRAYHLQDQGMDTVEANLALGLPVDARDFRLAQSIYEYLGIRSVKLLTNNPEKIQTLK
                     DAGINVVERIPLHVGENLENKRYLQTKADKLGHLMSE"
     gene            3271..3594
                     /locus_tag="ACFOAE_001705"
     CDS             3271..3594
                     /locus_tag="ACFOAE_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC6885151.1"
                     /translation="MIFSIIVPIYNVEKYLRCCVDSVLAENFADYEMILVDDGSPDGC
                     GKICDEYAGKYPHIKVIHQENGGLSDARNAGIRAAKGDYLIFLDSDDYWADTNCSKNA
                     RGDSL"
     gene            complement(3596..3961)
                     /locus_tag="ACFOAE_001706"
     CDS             complement(3596..3961)
                     /locus_tag="ACFOAE_001706"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885152.1"
                     /translation="MRQHIAEIFVFDVVADRVAENAVLIKRVIVKGKSLDKTRQFQTV
                     REILVNVSFWEKQIVFDDYFPPDDFCPRVGDIVPPLHQRFKMADKIIIRKVRPFGDDV
                     VIEGRGMQDQINLFVCKLL"
     gene            3950..4282
                     /locus_tag="ACFOAE_001707"
     CDS             3950..4282
                     /locus_tag="ACFOAE_001707"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HFC6885153.1"
                     /translation="MLAHLDRGVDFLVENRNSPIYGGLQKFVFDNIGYLRSISVRLYF
                     SKNIIVVYREYFSFKEKCRKIFGAKAIRPVFIGKTAFIIGLPILRLLVPPMLYPAIKA
                     VYQKFFSE"
     gene            4497..5834
                     /gene="ribBA"
                     /locus_tag="ACFOAE_001708"
     CDS             4497..5834
                     /gene="ribBA"
                     /locus_tag="ACFOAE_001708"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HFC6885154.1"
                     /translation="MTDTAGLRRRNLRQWIAEHYGGLQTRFAEAVALNTGELSALLKN
                     KSFGEKKARKIEQAAKMPAFWLDTEHTARPPEHTGKHTMSHISPIPEILADIKAGKMV
                     IITDAEDRENEGDLLMAAQFVTPEAINFMIKHARGLVCLPMDGEMVEKLGLPMMTQKN
                     GAQYGTNFTVSIEAAHGITTGISAADRALTIQTAVSPTAKPEDIVQPGHIFPLRAQKG
                     GVLVRAGHTEAGVDLAQMNGLIPASVICEIINDDGTMARMPELMKFAEEHKLKIGTIA
                     DLIEYRSRTESLLEDMGNAPVQTPWGEFQQHVYVDKLSGETHLALVKGTPSADTETLV
                     RVHEPFSVMDFIQANPRHSWSLPKALEHIQQAESGVVILLHRTEDGASLLDRTLPKGA
                     NQAYKWDSKSYGIGAQILAGLNVKKLRVLGQPSSFTGLTGFGLEVVGFEEAEK"
     gene            complement(5994..6110)
                     /locus_tag="ACFOAE_001709"
     CDS             complement(5994..6110)
                     /locus_tag="ACFOAE_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFC6885155.1"
                     /translation="MPSESLSDGILFGLENTYAVLSLKERIQKTKATGIYRK"
     gene            complement(6142..6478)
                     /locus_tag="ACFOAE_001710"
                     /pseudo
     CDS             complement(6142..6478)
                     /locus_tag="ACFOAE_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232504.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
BASE COUNT         1601 a         1691 c         1577 g         1609 t
ORIGIN      
        1 tccactataa aaatgccgtc caaacccatg tttgagacgg catttcgcta tagaagcaat
       61 caggcaacct gggtttgatg ctcgtctccc tgacgctcac ggatcaaacc taaacggtaa
      121 actgtttcac cttgttcacc caagagatcc tgaaccgcat cggcatcttc ggcagcaaca
      181 ataacgacca tgccgatgcc gcagttaaag gttcggtaca tttcttgggt ttccacattg
      241 cccgcctttt gaagccattg gaagagcttg ggcaattccc acgatttagc atcgatttgt
      301 gcaaccgtgt tttcaggcaa cacgcgcggc acgttttcgg taatgccgcc gccggtaatg
      361 tgtgccatac ctttaatggt aaatttttcc aaagcggcaa gaatcggttt cacatacaga
      421 cgggtcggcg caataacagc ctcacgcaag gttttgccat tatcaaactc ggcatccaaa
      481 tcgggattgt cgcgttcgat gattttacgg ataagggaat agccgtttga atgtgcgccg
      541 ttggaagcca aacccaatac cacatcgccc gcgccgatgc tgcggccggt aatgacattc
      601 tctttttcca ctacgccgac ggcaaaaccc gccaaatcgt attctccgac gggatacata
      661 cccggcattt cggcagtttc cccgccaatc agggcgcagc cggattcttc gcaaccttgt
      721 gcaatgcctt tgatgacatc ggttgcgcgc ggaacatcca attcgccgca ggcgaaataa
      781 tccaagaaaa acagaggttc tgctccttga accaaaatat cgttgacact cattgcaaca
      841 aggtcgatgc ccaccgtatc gtgtttatcc caatcaaagg caagtttgag cttggtaccc
      901 acgccgtccg taccgctgac caatacggga tttttatatt tcttgccgat ttcgaccaat
      961 gcgccgaagc cgcccaaatc ccccaatact tccgggcgca tcgtgcgttt ggcaaaaggt
     1021 ttgatgtttt cgaccagttg gtcgcctgcg tcgatatcga cacctgcatc gcggtaactc
     1081 aatgaagtac tcatcatttt tccttggtaa atggggattg gacggtaaaa taacggggcg
     1141 tattctacct tatttcgcgt ttgcaagttc agatttttag acaatattgt aaacaatccg
     1201 ccatatgccc gcgcgtgtcg ggtttggcgg gatcgtccgc aggattaacg ggcagaaacc
     1261 cgcctgccct tcccctcaat tccttatata tcgcgttcca tcaaaagacg cattgctttt
     1321 cttaaccatt ccttttggca gacgggcgga aggggttttt tgatgccatc atcaaaatca
     1381 atattttctt ctttccagtt gaaaccccgg cattaggggc ggtgaatctg attgcgggcg
     1441 gaagcacccg cttctgattc ggggtagaac aaatggcggc actttatgta ccgttctgcg
     1501 tgttgaaaca tataggcaga taaaaaagcc gcccgctgaa aagcagacga cttatgtttt
     1561 gtggcactaa tttgtcccga taagcattaa ctatatgatt tatttatcat tattggtgcg
     1621 gacggagaga ctcgaactct cacacctttc ggcgccagaa cctaaatctg gtgcgtctac
     1681 caatttcgcc acgtccgcat gggaattgga cgattataca gattttgttt ttttgtgcaa
     1741 ggttttcggc ggggctgttg atggcttggg gtttggggcg gtaaaatctg tttttcgtcc
     1801 gcctgacatc ggaatccggc ggttttttgt ttttattgac ggaatttggg tatgcctgct
     1861 gctttgatta aggattttct gctgactcag ggtttgaagc tgccgcttga cgaggttcgg
     1921 gcggcgtatc tgacggcgca gacggtaatg gatatgggga cggcttcgat agaccgttcg
     1981 gttttgtggc gcagtgatga ggattggaaa cttgccgatt acctgtcgtg cgacaatgtc
     2041 cgcgaagatg cactgaaacg gcttttcatg gctttggatt cggtgttttc gcgctcgaca
     2101 ggcgtgcgga gtgcggcggt ctatgccttg atgccatctg aaaaccaggc tttccaactg
     2161 atatgcctgt cccgacaggg cgaggttttg gaaaacctgt gggatttgga tgaagcggca
     2221 ggcaaggttt cgctggcttg ccgttcggcg caaagcggtt ggatgaatgt tgcctcggat
     2281 gtacgccgtt ggttggattt gggggagctt tcgggagaac gcaatcatgc ttcggcggcg
     2341 caaatttcca ttccggtctg cacggaaagt ggcggtgtgt tgggcgtggt tcatgtggaa
     2401 tttgaatgcg cagagtgtgc gggtacggca gcacaggtgg aatgggtggc tcttgccttg
     2461 gctttgtccg aacctttgaa actgctgttg ggtatgtctg ccggaaaaga tgggagtgaa
     2521 gatgtctgaa atgttgaacc atgtggcatc ctgccgcctg ccgaccgaat ggggcgtatt
     2581 tacgatgcac ggctttgaag aggcaaacgg gcaggaacac gtcgcgctga ccgtcggtaa
     2641 tttttcagac ggcaatccgg ttctgacgcg catccactcc gaatgcctga cgggcgatgc
     2701 gctgttctcg agaaaatgcg actgcggacc tcaacttgaa gcggccatga gggcggtaca
     2761 gacagagggg cgcggcatca tcgtctatct gcgtcaggaa ggacgcggca tcgggctgat
     2821 taacaaaatc cgcgcctatc atctgcaaga ccaaggtatg gatacggttg aagccaattt
     2881 ggcactcggg ctgcccgtcg atgcccgcga tttccgtttg gcgcaatcta tctacgaata
     2941 tctgggcatc cgctcggtca aactgctgac caacaacccc gaaaaaatcc aaaccctgaa
     3001 agatgcgggg attaacgtgg tcgaacgcat ccccctgcac gtcggggaaa accttgaaaa
     3061 caaacgctac ctccaaacca aagcagacaa gctgggacat ctgatgtcgg aataaggcaa
     3121 agttgcaggg aacgggcatc ctgcgccgcc tttcgggaaa caggtttcca taccttgata
     3181 aagcaataag ttttatagtg gatgcaaacg cattgcgagc gcgggtttga ggcatacgcg
     3241 caaacatctt aatataatgg attgatattt atgattttct ccatcatcgt ccctatttac
     3301 aatgtggaaa aatacctccg ctgctgcgtg gattccgtgc ttgccgaaaa ttttgccgat
     3361 tatgaaatga ttttggtcga tgacggttcg ccggacggct gcgggaagat ttgcgacgaa
     3421 tatgcaggca aatatccgca tataaaagtg attcatcaag aaaacggcgg gctgtcggat
     3481 gcccgcaacg ccggtatccg ggcggcaaaa ggcgattacc tgatcttttt ggacagcgac
     3541 gactattggg ccgataccaa ctgttcaaaa aacgcgaggg gggattctct ttgatttaca
     3601 acaacttgca gacaaaaagg ttgatttgat cctgcatccc tcgtccctca attaccacgt
     3661 catccccaaa ggggcggact tttcggataa tgattttgtc cgccattttg aaacgttggt
     3721 ggaggggcgg tactatatcg ccaacgcgtg gacaaaaatc gtcaggcggg aaataatcat
     3781 caaaaacaat ctgtttttcc caaaaggata cattcacgag gatttcccgt acagtttgaa
     3841 attggcgcgt tttgtcaaga cttttgcctt ttacgataac cctttttatc aataccgcgt
     3901 tctcggcaac tctatcagcc acaacgtcaa atacaaaaat ttcagcgata tgctggcgca
     3961 tctcgaccgg ggtgtggatt ttttagtcga aaacagaaat tcccccatct acggcggttt
     4021 gcaaaaattt gtcttcgaca atatcggcta tctgagatct atatcggtaa ggctttattt
     4081 ttccaaaaac attatcgttg tctaccgaga atatttttca tttaaagaga aatgcagaaa
     4141 gatattcggc gcgaaggcaa tccgtccggt ttttatcggg aagaccgcat tcatcatagg
     4201 attgccgata ttgcgcctgc tcgtaccgcc tatgctgtac ccggcaatca aggccgttta
     4261 tcaaaaattt ttttcggaat aagcttccgg caaaccccga atcggaagcg ggcgggaaga
     4321 aacagccgcc ccgccggcgg ggttgcggca atgccgtctg aagccacgaa tccggcttca
     4381 gacggcatct gtttaccaaa aagcaaataa ttcggtttgg caaaaaaaac agatttgctt
     4441 tttggtaaat acgcgcttac aatccgctac atccgatttc tacaaaggat gaaacgatga
     4501 ccgacacagc cggtctgcgc cgccgcaacc tgcggcaatg gatagcagaa cactacggcg
     4561 gtttgcaaac ccgttttgcc gaagccgttg ccctcaacac aggcgaactc tccgcccttt
     4621 tgaaaaacaa atccttcggc gagaaaaaag cccgtaaaat cgaacaggcg gcaaaaatgc
     4681 ccgccttctg gctcgatacc gaacacaccg cccgcccgcc cgaacacaca ggaaaacaca
     4741 ccatgtccca tatttccccc atccccgaaa tcctagccga catcaaagcc ggcaaaatgg
     4801 tcatcatcac cgatgccgaa gaccgagaaa acgaaggcga cctgctgatg gcggcgcaat
     4861 tcgtcacgcc cgaagccatc aacttcatga tcaaacacgc gcgcggcttg gtctgcctgc
     4921 cgatggacgg cgaaatggtc gaaaaactcg ggctgccgat gatgacccaa aaaaacggcg
     4981 cgcaatacgg caccaacttt accgtctcca tcgaagccgc acacggcatt accaccggca
     5041 tttccgccgc cgaccgcgcc ctgactattc aaaccgccgt ttccccgacc gctaaacccg
     5101 aagacatcgt ccaacccggt catatctttc cgcttcgcgc ccaaaaaggc ggcgtactcg
     5161 tccgcgccgg acacaccgaa gccggcgtcg acctggcgca aatgaacggg ctgattcctg
     5221 cctccgttat ttgcgaaatc atcaacgacg acggcacgat ggcgcgtatg cccgaactga
     5281 tgaaattcgc cgaagaacac aagctcaaaa tcggcacgat tgccgacctc atcgaatacc
     5341 gcagccgtac cgaaagcctg cttgaagaca tgggcaatgc gcctgtacaa accccgtggg
     5401 gcgagttcca acaacacgtt tacgtcgaca aactctccgg cgaaacccac ctcgccctcg
     5461 tcaaaggcac gccctccgcc gacaccgaaa ccctcgtccg cgtccacgaa cccttcagtg
     5521 tgatggactt cattcaagcc aacccgcgcc attcatggtc gctgcccaaa gcccttgagc
     5581 acatccaaca agccgaaagc ggcgtcgtca tcctcttaca ccgcaccgaa gacggcgcat
     5641 ccctgctcga ccgaacccta cccaaaggcg caaaccaagc ctacaaatgg gacagcaaaa
     5701 gctacggcat cggcgcacaa atcctcgccg gcctcaacgt caaaaaactg cgcgtcctcg
     5761 ggcagccctc atctttcacc ggcctgaccg gcttcggttt ggaagtcgtc ggctttgaag
     5821 aagcggaaaa ataatatagt aaattcaaat actttatatt tgctttattt attgcattat
     5881 ttccgtgcaa acgaaaaccc ggtctgttgg gttggatttt gttttttcaa atttcgggta
     5941 acttctaatt cgtcattccc gcgctggcgg gaatccggtt cgtcgggttt ttgtcatttc
     6001 cgataaattc ctgtggcttt ggttttttgg attctctctt tcagggaaag aacggcataa
     6061 gtattttcca aaccaaacaa aatgccgtct gaaaggcttt cagacggcat tttaagtttg
     6121 accggtttca ttcatcggta tttatgaatt gaatttcaac atcgccaatc tatccttaat
     6181 ctctttttcc aattcggcag attcggcgaa aagtttatcc aaatccgctg aaaatcccgc
     6241 cattttttgc gcaaattcgt cggcggaaat atccacataa tcaatcttta cctcgaaata
     6301 ctgccccgcc gacaagctgt gattcttcgc tttgatttca tcgtagccga ttaccacact
     6361 gaaatcttcc actgcctgtt tgtgcgtgaa ggtattgcag atttttttgt tcttcttcgc
     6421 gggaaagtac ggtttttttg ccgtctttaa ttttttcgcc caagcccgat gcgtcgat
//
LOCUS       DAXIDM010000104         6272 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000104 DAXIDM010000000
VERSION     DAXIDM010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6272
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.104"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(63..623)
                     /gene="sodC"
                     /locus_tag="ACFOAE_001711"
     CDS             complement(63..623)
                     /gene="sodC"
                     /locus_tag="ACFOAE_001711"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC"
                     /protein_id="HFC6885156.1"
                     /translation="MNMKTLLALAVSAVCSVGVAQAHEHNTIPKGASIEVKVQQLDPV
                     NGNKDVGTVTITESNYGLVFTPDLQGLSEGLHGFHIHENPSCEPKEKEGKLTAGLGAG
                     GHWDPKGAKQHGYPWQDDAHLGDLPALTVLHDGTATNPVLAPRLKHLDDVRGHSIMIH
                     TGGDNHSDHPAPLGGGGPRMACGVIK"
     gene            complement(1040..2080)
                     /gene="mutY"
                     /locus_tag="ACFOAE_001712"
     CDS             complement(1040..2080)
                     /gene="mutY"
                     /locus_tag="ACFOAE_001712"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFC6885157.1"
                     /translation="MNTPIPFSERLIRWQKQHGRHHLPWQVKNPYCVWLSEIMLQQTQ
                     VATVLDYYPRFLEKFPTVQTLAAAPQDEVLSLWAGLGYYSRARNLHKAAQQVVRQFGG
                     TFPSERKDLETLCGVGRSTAAAICAFSFNRRETILDGNVKRVLCRVFARDGNPQDKKF
                     ENSLWTLAESLLPSENADMPAYTQGLMDLGATVCKRTKPLCHQCPMADICEAKKQNRT
                     AELPRKKTAAEVPTLPLYWLIIRNRNGAILLEKRPAKGIWGGLYCVPCFESLNGLSDF
                     AAKFSLTMADMDEQTALTHRLTHRLLMITPFEGQMPSESPSDGIWIKPAHLKDYGLPK
                     PLEIYLNGNRLE"
     gene            2243..3284
                     /locus_tag="ACFOAE_001713"
                     /pseudo
     CDS             2243..3284
                     /locus_tag="ACFOAE_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
     gene            complement(3307..3525)
                     /locus_tag="ACFOAE_001714"
     CDS             complement(3307..3525)
                     /locus_tag="ACFOAE_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885158.1"
                     /translation="MPSEALSSLRRHFAAWRRSRHTRQHHSDILPLKCPSAFRIIKIT
                     FSSFDSSRTAHTTRLKKCRLKRIQTASA"
     gene            complement(3540..4178)
                     /locus_tag="ACFOAE_001715"
     CDS             complement(3540..4178)
                     /locus_tag="ACFOAE_001715"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_function: GO:0016833 - oxo-acid-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFC6885159.1"
                     /translation="MSKLTPREILTAGAVVPVMAIDDLSTAIDLSHALVEGGIPTLEI
                     TLRTPVGLDAIRLIAKEVPNAIVGAGTVTNPEQLKAVEDAGAVFAISPGLHESLAKAG
                     RNSGIPLIPGVATPGEIQLALEHGIDTLKLFPAEVVGGKAMLKALYGPYADVRFCPTG
                     GISLATAPDYLALPNVLCVGGSWLTPKEAVKNKDWDTITRLAKEAAALKPKA"
     gene            complement(4359..6194)
                     /gene="edd"
                     /locus_tag="ACFOAE_001716"
     CDS             complement(4359..6194)
                     /gene="edd"
                     /locus_tag="ACFOAE_001716"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HFC6885160.1"
                     /translation="MNTTPIHSKLAEITGRIIERSRPTREKYLAKIRSAKQMGRLERN
                     QLGCSNLAHGYAAMPKSIKIEMLQETVPNLGIITAYNDMVSAHQPFKDFPDQIKDEAQ
                     KNGATAQVAGGTPAMCDGITQGYAGMELSLFSRDVIAMSTAVGLSHQMFDGSLFMGVC
                     DKIVPGLMIGALSFGHIPGIFVPAGPMSSGIGNKEKARTRQLFAEGKVGRNELLKSEM
                     GSYHSPGTCTFYGTANSNQMMMEMMGVHLPAAAFVHPYTDLREALTRYAAGHLARGIK
                     NGTIKPLGEMLTEKSFINALIGLMATGGSTNHTMHLVAMARAAGVILNWDDFDEISSI
                     IPLLIRVYPNGKADVNHFTAAGGLPFVIRELLNAGLLHDDVDTVVGHGMRHYTKEPFL
                     IDGKLEWREAPETSGNDDILRKADNPFSPDGGLRLMKGNIGRGVIKVSAVREGCRIIE
                     APAIVFNDQREVLAAFERGELERDFVCVVRYQGPRANGMPELHKLTPPLGILQDRGFK
                     VALLTDGRMSGASGKVPASIHMTPEALMGGNIAKIRTGDLIRFDSVSGELNVLINETE
                     WNAREVESIDLGANQQGCGRELFANFRSMTSSAETGAMSFGGEFA"
BASE COUNT         1391 a         1522 c         1756 g         1603 t
ORIGIN      
        1 ctaaatatct agcaaaaaag tgcggtcaaa attcaccgca cttttcgttt cgaacaatcg
       61 aattatttaa tcacgccaca tgccatacgt gggccgccac cgccaagtgg agctggatga
      121 tcggagtgat tatcaccacc cgtgtggatc ataatagagt gaccgcgaac atcatctaaa
      181 tgtttaagac gtggtgctaa aacaggattt gttgctgtgc catcatgcaa tacagttaat
      241 gcaggtaaat cacctaagtg tgcatcatct tgccatgggt aaccatgttg ttttgcacct
      301 ttaggatccc agtgaccgcc tgcgcctaaa ccagctgtca atttaccttc tttttctttt
      361 ggctcacagc ttgggttttc atggatgtgg aaaccatgta agccttcgct taatccttgt
      421 aaatcagggg taaacacaag accatagtta gattcagtaa tagtcactgt acccacatct
      481 ttgttaccgt ttactggatc aagttgttgc actttcactt caatagaagc acctttaggt
      541 atcgtattat gctcgtgtgc ttgcgcaaca ccaactgaac atactgcact aaccgctagt
      601 gctaataagg ttttcatatt cattgcaatc tcctttattg cagtaaaaac tcgcgactat
      661 tttagtcaat tttgttttaa aagccgataa atttttacga aaattttaca ttaattgtta
      721 tttgcagaaa attagaaccc gttatcacgt cttggataaa tgccaaaacc attgtgattc
      781 agagaattaa aaagaaaaat ttcggaatcc tcatcctttt ctgaaacctg attgcggtat
      841 ccatggcttt gtctttgtca tttaagtttg tgttcatgtt tttgaccttc tttgcttttt
      901 aaatcctttt taaattgccg acttctaccg ttccaaatgt cccatttgaa cattatcccg
      961 ccgcctaaaa tacgacccaa attcatcggt tgttcttgct gcgatacctg caaacaacag
     1021 ttcaatgggt ttattttgtt tattctaacc tattaccgtt taaataaatt tccaaaggct
     1081 tgggcaaacc gtaatctttc aaatgcgccg gctttatcca aatgccgtct gaagggcttt
     1141 cagacggcat ttgtccttca aacggcgtaa tcatcagcaa ccggtgcgtc agccggtggg
     1201 tcagggcggt ttgttcgtcc atatctgcca tggtcaggga gaatttggcg gcaaagtcgg
     1261 aaagcccgtt caaactttca aaacacggca cgcaatacag cccgccccaa atgcctttgg
     1321 cggggcgttt ttccagcaaa atcgcgccgt tccggttgcg gataatcagc cagtaaagcg
     1381 gcagggtcgg tacttcggcg gcggtttttt tgcgcggcag ctcggcggtg cggttttgct
     1441 ttttcgcttc gcagatgtcc gccatcgggc attggtggca caagggtttc gtccgtttgc
     1501 acacggtcgc gcccaaatcc atcaaacctt gtgtataggc aggcatatcg gcgttttcag
     1561 acggcagcag gctttcggca agtgtccaga gcgagttttc aaattttttg tcctgcggat
     1621 tgccgtcgcg ggcgaacacg cggcagagta cgcgtttgac gttgccgtcc aaaatggttt
     1681 cgcggcggtt gaaggagaag gcgcaaatgg cggcggcggt gcttctgcct acgccgcaga
     1741 gggtttccaa gtctttgcgc tccgacggaa acgtgccgcc gaattgcctg acgacttgtt
     1801 gcgcggcttt gtgcaggttg cgcgcgcggc tgtaatagcc caagcccgcc cacaacgaca
     1861 acacttcgtc ttgcggcgcg gcggcaagcg tctgaacggt cgggaatttt tctaagaagc
     1921 gcggatagta gtccaacacg gtggcgactt gcgtttgctg gagcatgatt tcggaaagcc
     1981 agacgcaata agggtttttg acctgccaag ggaggtggtg gcgaccgtgt tgtttttgcc
     2041 agcggatgag ccgttcggag aaggggatgg gtgtgttcat taatatcaat cggtggtttt
     2101 atttatattt aaaacggtat gttattgtat aacattgtga aaataattct tattgactta
     2161 ttttttgtag gggcatataa ctcatataaa gaaactttat tgcggtattg aaattattta
     2221 tcaacaagca aggagtatca gcatgaaagc aatggtttat cacggcgcaa acgacatccg
     2281 ttttgaagaa aaaccccgtc cgcagattat cgatccgacc gatgcggtgg tgaaaatcgt
     2341 caaaaccacg atttgcggta ccgatttggg tatttggaaa ggcaaaaaaa cccgaagtcg
     2401 ccgacggtcg tattctcggt catgaaggca tcggtattgt agaagaagtc ggcgatgctg
     2461 taaaaaacat caaagtcggc gataaagtca ttatttcatg cgtcagcaaa tgctgtactt
     2521 gcgacaactg caaaatccaa ctttattcgc attgccgcaa cggcggctgg attttgggct
     2581 acatgattga cggcacgcag gcagaatacg tccgcacgcc ttatgccgac aacagcctcg
     2641 tgccgctgcc cgacaacgtc aacgaagaag tcgccctgtt gttgagcgac gctttgccga
     2701 ccgcacacga aatcggcgtg caatacggcg atgtcaaacc cggcgacacc gtattcatcg
     2761 caggtgccgc tcctgtcggt atgtccgcct tgttgaccgc ccaactgtat agccccgccg
     2821 ccattatcgt gtgcgatatg gacgaaaacc gtttgaaact ggcgaaagag ttgggcgcga
     2881 cccataccat cagccccgct tccggcgacg tctccaaaca agttttcgcc atcgtcggcg
     2941 aagacggcgt agattgtgcc atcgaagcgg tcggtatccc tgcaacttgg aatatgtgcc
     3001 aagacatcgt gaaacccggc ggccatatcg ccgttgtcgg cgtacacggt caatccgttg
     3061 atttcaaact ggaaaaactg tggattaaaa agcttgccat cactaccggc ctggtaaacg
     3121 ccaataccac cgaaatgctg atgaaggcaa tttccagcag ctccgtcgat tacaccaaaa
     3181 tgttgaccca ccgtttcaaa ttcagcgaat tggaaaaagc ctacgacgtg ttcaaacacg
     3241 ccgccgaaaa tcaagcgatg aaagtggttt tggaagcgga ttaatcggcg ttgaatcagt
     3301 tgttttttaa gcggatgccg tctgaatgcg tttcagacgg cattttttca gccgcgtagt
     3361 atgggctgtc cggctgctgt cgaatgaact gaacgttatt tttattatgc ggaaggcgga
     3421 tgggcatttt aggggcagta tgtcggagtg gtgctgccgt gtatgccgac tgcgccgcca
     3481 agcggcaaaa tgccgtctga gactggaaag ggcttcagac ggcattttta cgatgcggtt
     3541 caggctttgg gtttcaatgc cgccgcttct ttggcgagac gggtgatggt gtcccagtct
     3601 ttgtttttca cggcttcttt cggcgtcagc catgagccgc cgacgcacag gacgttgggc
     3661 agtgccaagt aatcgggcgc ggtggcgagg ctgatgccgc ctgtcgggca gaagcgaaca
     3721 tcggcgtaag ggccgtacag ggctttgagc atggctttgc cgccaacgac ttcggcaggg
     3781 aagagtttga gggtgtcgat gccgtgttcc aaagccagtt ggatttcgcc cggggtggca
     3841 acaccgggaa tcagggggat gccgctgttg cggccggctt tggcgaggga ttcatgcagc
     3901 cccgggctga tggcgaaaac cgcgcctgcg tcttcgacgg ctttaagctg ttcgggattg
     3961 gttaccgtac ctgcgccgac gatggcgttg ggcacttctt tggcaatcag gcggatggca
     4021 tcgaggccga caggggtgcg cagggtgatt tcgagggtag ggatgccgcc ttcgacaagg
     4081 gcgtgggaca aatcgatggc ggtgcttaag tcgtcaatcg ccattaccgg cacaactgcg
     4141 ccggcggtca aaatttcgcg gggggtcagt ttggacattt cggttctccg ggtggaatgg
     4201 ggtattttat taagatggga caggtcgtag gtcggattca agaaaccgac atcttggacg
     4261 gctgtgtcgg attcgagaat ccaacctacg tctatcttaa aacacttgaa taatttttca
     4321 gacggccttc ggtctgaaaa ggccgtctga aacgcgcatc aggcaaattc gccgccgaag
     4381 ctcatcgcgc cggtttcggc gctgctggtc atgctgcgga agttggcgaa aagttcgcgg
     4441 ccgcagcctt gttggttcgc gcccaagtcg atgctttcga cttcgcgggc attccattcg
     4501 gtttcgttaa tcaggacgtt gagttcgccg ctaacggagt cgaagcggat caggtcgccg
     4561 gtacggattt tggcgatgtt gccgcccatc agggcttcgg gcgtcatgtg gatggaggcc
     4621 ggaactttgc cggatgcgcc ggacatacga ccgtcggtca gcagtgccac tttgaagccg
     4681 cggtcttgca ggatgcccaa aggcggggtc agtttgtgca attcgggcat accgttggca
     4741 cgcgggcctt ggtagcggac gacgcacaca aaatcgcgtt ccaactcgcc gcgttcaaac
     4801 gcagccaaca cttcgcgttg gtcgttgaac acgatggcag gcgcttcaat aatgcggcag
     4861 ccttcgcgca cggcggacac tttaatcacg ccacgtccga tgttgccttt catcaggcgc
     4921 agaccgccgt cgggggagaa cgggttgtca gctttacgca ggatgtcgtc gttgccgctg
     4981 gtttcggggg cttcgcgcca ttcgagtttg ccgtcgatga ggaaaggctc tttggtgtag
     5041 tggcgcatac cgtgtccgac gacggtatcg acatcgtcgt gcaacaggcc tgcattcagc
     5101 aattcgcgga taacgaaagg cagtccgccc gctgcggtaa agtgattcac gtcggccttg
     5161 ccgttcggat aaacgcggat gagtagtggg atgatggagg aaatttcgtc gaagtcgtcc
     5221 cagttcaaaa tcacgccggc cgcacgcgcc atagcgacga ggtgcatggt gtggttggtc
     5281 gaaccgccgg ttgccatcag gccaatcaag gcgttgataa aggatttttc ggtcaacatt
     5341 tcgcccaaag gtttaatcgt gccgtttttg atgccgcgcg cgaggtgtcc ggcggcgtag
     5401 cgagtcagcg cttcgcgcag gtcggtgtaa gggtggacga aggcggcggc aggcaggtgc
     5461 acgcccatca tttccatcat catttggttg gagtttgccg tgccgtagaa agtgcaggtg
     5521 cccgggctgt ggtaagaacc catttcgctt ttcaaaagtt cgttgcgtcc gaccttgcct
     5581 tcggcgaaaa gctggcgggt gcgggctttt tctttgttgc cgataccgct ggacatcggg
     5641 cctgcgggga cgaagatacc cggaatatga ccgaacgaaa gcgcgcctat catcaaaccc
     5701 ggaacgattt tgtcgcatac gcccataaac aggctgccgt caaacatttg atgcgacagc
     5761 ccgacggcgg tactcatggc aatcacgtcg cgggagaaca gcgacagttc catgccggcg
     5821 tagccttgcg tgatgccgtc gcacatggcg ggcgtgccgc cggcgacttg ggcggtcgcg
     5881 ccgtttttct gcgcttcgtc tttgatttgg tcagggaagt ctttaaacgg ctggtgtgcg
     5941 gaaaccatgt cgttgtaggc ggtgatgatg cctaagttgg ggacggtttc ctgaagcatt
     6001 tcgattttga tacttttagg catggcagca tagccgtgtg ccaagttgct gcagccgagc
     6061 tggttgcgct ctaagcgtcc catttgtttg gcactgcgga tcttcgccag atatttttca
     6121 cgcgtcggac ggctgcgttc aataatgcgc ccggtgattt cggcgagttt ggagtggata
     6181 ggagtagtgt tcacggtcgg tctcctgtcg gaacgggggg tattggggat ttgtttgtgc
     6241 gtttctgatt tttgtatcgg gtattcagac gg
//
LOCUS       DAXIDM010000105         6216 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000105 DAXIDM010000000
VERSION     DAXIDM010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6216
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.105"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(85..1596)
                     /gene="ubiB"
                     /locus_tag="ACFOAE_001717"
     CDS             complement(85..1596)
                     /gene="ubiB"
                     /locus_tag="ACFOAE_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HFC6885161.1"
                     /translation="MKWLKRLTVIVGTFYRYRLAGLCASLMGSGWICALLKMMPQSSK
                     LKNEPPAVRLRLALESLGPIFIKFGQVLSTRPDLIPHDYAVELAKLQDKVPPFDARLS
                     REQIEKSLGQSIEKLYAEFETEPIASASIAQVHKARLHSGERVAVKVLRPNLLPLIEQ
                     DLSLMRFGAAWVERLFSDGRRLKPLEVVAEFDKYLHDELDLMREAANAGQLGRNFQNS
                     NMLIVPKVFYDYCTSDVLTIEWMDGTPVSDIAKLKADGIDLHKLADYGVEIFFTQVFR
                     DGFFHADMHPGNILVAADNRYIALDFGIVGTLTDYDKRYLAINFLAFFNRDYRRVATA
                     HIESGWVPADTRAEELEAAVRAVCEPVFNKPISQISFGLVLMRLFEVSRRFNVEIQPQ
                     LVLLQKTLLNIEGLGRQLDPDLDLWKTAKPFLVKWMNGQVGPKALWRNLKNEAPDWAQ
                     IIPSLPRKISALIDENRQQEMRDAYIHLVKVQQRQSLWLAVIAVVLLLILLLK"
     gene            complement(1631..1846)
                     /locus_tag="ACFOAE_001718"
                     /pseudo
     CDS             complement(1631..1846)
                     /locus_tag="ACFOAE_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(2053..2199)
                     /locus_tag="ACFOAE_001719"
     CDS             complement(2053..2199)
                     /locus_tag="ACFOAE_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885162.1"
                     /translation="MPSERSDGIFTFGKYIIGMNSHIIRLFEDESGFPKGTGGTVSGV
                     FVPL"
     gene            complement(2216..2554)
                     /gene="erpA"
                     /locus_tag="ACFOAE_001720"
     CDS             complement(2216..2554)
                     /gene="erpA"
                     /locus_tag="ACFOAE_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HFC6885163.1"
                     /translation="MSDESPIIFTDSCCAKVADLIAEENNPDLKLRVFVNGGGCSGFQ
                     YGFTFDEIKNDDDFEIEKNGLVFLVDPMSYQYLVGAEIDYTESLQGSQFVIRNPNAET
                     TCGCGSSFSV"
     gene            complement(2686..3372)
                     /locus_tag="ACFOAE_001721"
     CDS             complement(2686..3372)
                     /locus_tag="ACFOAE_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC6885164.1"
                     /translation="METFKDRLVFLWKSEARQAKIASDIEMTIAGFSRIWNEGGLPKS
                     ETLKKIKQLKGCSIDWLLTGEGNPFPDEAPKKSLAYDTLGNEVDTDEFVFVPRYDIRA
                     AAGYGQFVDHEEPVFTMAFRRHWIENYVTRDTKNLSVISVKGDSMEGVLNDGDSILVN
                     HGENTPRDGLYVLRINENLLVKRLQIVPGGIINVISANEAYPAFEINLNDLTDDVEII
                     GRVEWFGRTI"
     gene            3560..3832
                     /locus_tag="ACFOAE_001722"
     CDS             3560..3832
                     /locus_tag="ACFOAE_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885165.1"
                     /translation="MKKTGKYLIYTAAFTAFCFAFQENRSEAKQPDITLSASLCEQFN
                     ILNAKDMDAEQVSLSKECDIIESSHDWEKEYGNLNEQEMLAGIVYE"
     gene            4040..5968
                     /gene="dnaK"
                     /locus_tag="ACFOAE_001723"
     CDS             4040..5968
                     /gene="dnaK"
                     /locus_tag="ACFOAE_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFC6885166.1"
                     /translation="MAKVIGIDLGTTNSCLAISENGQTKVIENAEGARTTPSVIAYLD
                     GGEILVGAPAKRQAVTNAKNTIYAAKRLIGHKFEDKEVQRDIESMPFEIIKANNGDAW
                     VKAQGKELSPPQISAEVLRKMKEAAEAYLGEKVTEAVITVPAYFNDSQRQATKDAGRI
                     AGLDVKRIINEPTAAALAFGMDKGDNKDRKVAVYDLGGGTFDISIIEIANLDGDKQFE
                     VLATNGDTFLGGEDFDQRLIDHIIAEFKKEQGIDLKQDVMALQRLKEAAEKAKIELSS
                     GQQTEINLPYITMDATGPKHLAMKITRAKFESLVEDLITRSIEPCKIALKDAGLSTGD
                     IDDVILVGGQSRMPKVQEAVRDFFGKEPRKDVNPDEAVAVGAAIQGEVLSGGRSDVLL
                     LDVTPLSLGIETMGGVMTKLIQKNTTIPTKASQVFSTAEDNQSAVTIHVLQGERERAS
                     ANKSLGQFNLGDIAPAPRGMPQIEVTFDIDANGILHVSAKDKGTGKAANITIQGSSGL
                     SEEEIERMVKDAEANAEEDKKLTELVASRNQAEALIHSVKKSLADYGDKLDAAEKEKI
                     EAALKEAEEAVKGDDKAAIDAKAEALGTASQKLGEMVYAQAQAEAQAGESEQANASAK
                     KDDDVVDADFEEVKDDKK"
BASE COUNT         1797 a         1648 c         1379 g         1392 t
ORIGIN      
        1 ggcaacgccg tactggtttt tgttaatcca ctataaccga tttccttata aacgggcgga
       61 gtcgggcgat gattcggaca aagcctattt caaaagcaaa atcagcagca aaacaaccgc
      121 aatcacagcc agccacaggc tttgccgctg ctgcactttg accaaatgga tataggcatc
      181 acgcatttcc tgctggcggt tttcatcaat caacgcactg attttgcgcg gcaatgaagg
      241 aatgatttgc gcccagtcgg gggcttcgtt tttgaggttg cgccaaaggg ctttagggcc
      301 gacctgcccg ttcatccatt tcaccaaaaa cggtttggcg gttttccaca agtccaaatc
      361 gggatcgagc tggcggccca agccttcgat gttgagcagc gttttttgca gcagcacaag
      421 ctgcggttgg atttcgacat tgaagcggcg gctgacttca aacaggcgca tcagcaccaa
      481 gccgaaggaa atctgcgaaa tcggtttgtt gaacaccggt tcgcacacgg cgcggacggc
      541 ggcttccaat tcttccgcac gcgtgtcggc aggcacccag cccgattcga tgtgggcggt
      601 ggcgacgcgc cggtaatcgc ggttgaagaa ggcgaggaag ttgatggcga ggtagcgttt
      661 atcgtaatcg gtcagcgtgc cgacgatgcc gaaatcgagg gcgatgtagc ggttgtcggc
      721 ggcaaccaaa atattgccgg ggtgcatatc cgcgtggaaa aaaccgtcgc ggaagacctg
      781 cgtgaaaaag atttccacgc cgtaatcggc gagtttgtgc aaatcgatgc cgtctgcttt
      841 gagtttggcg atgtcggaaa ccggcgtgcc gtccatccat tcgattgtca gcacgtcgct
      901 ggtgcagtag tcgtaaaaca ccttgggcac aatcagcata ttgctgtttt ggaaattgcg
      961 cccgagctgt ccggcattgg cggcttcgcg catcaaatcc aactcgtcgt gcaggtattt
     1021 gtcgaactcc gccaccactt cgagcggctt cagacgcctg ccgtctgaaa acaagcgttc
     1081 gacccaggcc gcgccgaaac gcatcagcga caaatcctgt tcgataaggg gcaaaaggtt
     1141 ggggcgcaaa actttaaccg ccactcgttc gcccgaatgc aggcgggctt tgtgtacttg
     1201 ggcgatggac gcgctggcga tgggctcggt ttcaaattcc gcatacagct tttcgatgga
     1261 ctgacccaac gatttttcga tttgttcacg cgaaagccgc gcgtcaaaag gcggcacttt
     1321 gtcttgcagc tttgccagtt cgacggcgta atcgtgcgga atcaaatcgg ggcgtgtgga
     1381 caaaacctgc ccgaacttga tgaaaatcgg ccccaggctt tccaaggcaa ggcgcagacg
     1441 gacggcaggc ggttcgtttt tcaatttgga cgactgcggc atcattttca gcagagcgca
     1501 tatccaaccg ctacccatca gcgaagcaca cagacctgcc agccgatagc ggtaaaaagt
     1561 cccgacaatg accgtcaggc gtttcaacca tttcatatat aaaatcccga atacagcatt
     1621 tatcggacaa tcaaaaaatc ttaccgagca gatagcccaa aaaggcaatc agcagcccga
     1681 aaagcagcgg tttgatattg cgggtcggcg gttcgggttg cgaaggtgcg gaaatatcat
     1741 cttcccgccc gccatgaagt tcaagatatt cgggcatttc cccatccgcg ccctctcttt
     1801 cgccctcacc ttcctccggc ggcacgaccg tttctaactc catatgtagt ggattaacaa
     1861 aaatcaggac aagacgacga agccgcagac agtacaaata gtacgaaacc gattcacttg
     1921 gtgcttcagc accttagaga atcgttctct ttgagctaag gcgaggcaac gccgtactgg
     1981 tttttgttaa tccactatat ctccgggtaa taatatccaa acccaaatag ctgaaataat
     2041 cgtgcaactc aatcataagg gaacaaatac gcctgatacc gttccgcccg ttcctttcgg
     2101 gaaacccgat tcatcttcaa acaatcggat tatatgtgaa ttcatcccga taatatattt
     2161 tccaaaagta aaaatgccgt ctgaacgttc agacggcatc acacaaacca agcggtcata
     2221 cggaaaacga cgatccgcaa ccgcaggttg tttccgcatt cggattgcgg atgacgaatt
     2281 gcgaaccctg caaactttcc gtatagtcga tttccgcacc gaccagatat tgatagctca
     2341 tcggatcgac caaaaagacc aaaccgtttt tctcaatttc aaaatcgtcg tcgtttttga
     2401 tttcgtcaaa agtaaatccg tactggaaac ccgaacagcc gccgccattg acaaaaaccc
     2461 gcaatttcaa atcgggattg ttttcttcgg caatcaaatc ggcaactttg gcacagcagc
     2521 tgtcagtaaa aataataggg ctttcatccg acatggtgtt attccttaat ataatatttt
     2581 ctgcattctc tctcaaaccc cctttaaagg caagcaggct tcgcctttga aaaaggaatt
     2641 gttccaatag ataagtttga ccgcctgcaa tttcaagccc caaactcaaa tcgtcctgcc
     2701 gaaccactcg acacgcccga taatctccac atcatcggtc aaatcgttca aattgatttc
     2761 aaaagcagga taagcctcgt ttgcagaaat cacattgata atcccgcccg gtacaatctg
     2821 taaacgttta accagcagat tttcattaat ccgcaacaca tacagaccgt ccctcggcgt
     2881 attttcacca tgattgacca aaatcgaatc gccgtcattc aaaaccccct ccatcgaatc
     2941 ccccttgacg gaaattacag acaggttttt cgtatcgcgg gtaacataat tctcaatcca
     3001 atgccgtctg aacgccattg taaataccgg ttcctcatga tcgacaaact gcccgtatcc
     3061 cgcagccgcc cgaatatcat atctcggcac aaagacaaac tcgtccgtat cgacttcatt
     3121 tcccaaggta tcgtaagcaa gggatttttt tggggcttca tccggaaacg gattaccctc
     3181 cccggtcagc agccaatcga tactacaccc cttcaactgc ttgatttttt tcaatgtttc
     3241 agactttggc agaccgcctt cattccatat cctgctgaag cccgcaatcg tcatttcaat
     3301 atcggatgcg atttttgcct gcctcgcttc gcttttccat aaaaaaacca gtctgtcttt
     3361 aaaggtttcc ataaatatcc ttccactccc cttcattcaa tcatctaaag taaacatgaa
     3421 atatatttta ccttagctat ccaaaaaacg gaacaattat gataaactaa atttaaatta
     3481 tgatttttct tacttaatac ataatttttc agatttttcc ataggtttaa tcctgaattg
     3541 acagaaaaag gatagaaaaa tgaagaaaac cggcaaatat cttatctata ctgcggcatt
     3601 taccgcattc tgctttgcct tccaagaaaa ccgttctgaa gccaaacagc ccgacatcac
     3661 tttatccgca tccctgtgcg aacaattcaa catactgaac gccaaagata tggatgcaga
     3721 acaagtctcc ctttccaaag aatgcgacat catcgagtct tcacacgact gggaaaaaga
     3781 gtacggcaac ttgaacgaac aggaaatgct cgccggcatc gtctacgaat aaacctgcct
     3841 gccatttgaa atattatgct tgaatgcatt ggagccaaat gtattaaatc aaatataaaa
     3901 ccaatatatt cataaagtta tatacttata gccatgctgt agcttgaaac agcccgccgc
     3961 ccgccctatt tacagcccat cgggacaaaa tgttccaaca tatttctcaa aataagcaaa
     4021 atcaaatagg attatccaca tggcaaaagt aatcggtatc gacttaggta caaccaactc
     4081 ttgtttggcc atttccgaaa acggtcaaac caaagttatc gaaaacgcag aaggcgcacg
     4141 caccacgccg tccgttatcg cttatttgga cggcggcgaa atcctcgtcg gcgcgcctgc
     4201 caaacgccaa gcggtaacca acgccaaaaa cactatttac gccgccaaac gtttgatcgg
     4261 ccacaaattt gaagacaaag aagtccaacg cgacatcgaa tctatgcctt tcgaaatcat
     4321 caaagccaac aacggcgacg catgggtaaa agcacaaggc aaagagctgt ctcctcctca
     4381 aatttccgca gaagtcctgc gtaaaatgaa agaagccgcc gaagcttact tgggcgaaaa
     4441 agtaaccgaa gccgtgatta ccgtccctgc ctacttcaac gacagccaac gtcaagccac
     4501 caaagacgca ggccgtatcg ccggtttgga cgtgaaacgc atcatcaacg agccgaccgc
     4561 agccgctttg gcattcggta tggacaaagg cgacaacaaa gaccgcaaag tagccgtata
     4621 tgacttgggc ggcggtactt tcgatatttc catcatcgaa atcgccaacc tcgacggcga
     4681 caaacaattc gaagtattgg caaccaacgg cgataccttc ttgggcggtg aagacttcga
     4741 ccaacgcctc atcgaccaca tcatcgccga gttcaaaaaa gaacaaggca ttgatttgaa
     4801 acaagacgtg atggctctac aacgcctgaa agaagctgcc gaaaaagcca aaatcgaatt
     4861 gtccagcggc cagcaaaccg aaattaacct gccgtacatc accatggacg caaccggccc
     4921 gaaacacttg gcgatgaaaa ttacccgcgc caaattcgaa agcctggttg aagacctgat
     4981 tacccgctct atcgaacctt gcaaaattgc attgaaagat gccggcttga gcaccggcga
     5041 catcgacgac gtaatcttgg tcggcgggca gtcccgtatg ccgaaagtac aagaagccgt
     5101 gagagacttc ttcggcaaag aaccgcgcaa agacgtgaac cctgacgaag ccgttgccgt
     5161 aggcgcagcg atccaaggcg aagtattgag cggcggccgc agcgacgtat tgctactgga
     5221 cgtaacccct ctgtccttgg gtatcgaaac catgggcggc gtgatgacca agctgattca
     5281 aaagaacacc accatcccga ccaaagcgtc gcaagtgttc tctaccgccg aagacaacca
     5341 aagcgcagta accatccacg tactgcaagg cgaacgcgaa cgcgcttctg ccaacaaatc
     5401 tttgggtcag ttcaacttgg gcgacatcgc acccgcaccg cgcggtatgc cgcaaatcga
     5461 agtaaccttc gacatcgacg ccaacggcat cctgcacgtt tccgccaaag acaaaggcac
     5521 tggcaaagcg gccaacatta ccatccaagg ttcttcaggt ttgagcgaag aagaaatcga
     5581 acgcatggtg aaagatgccg aagccaatgc tgaggaagat aaaaagctga ctgaattggt
     5641 cgcttcccgc aaccaagccg aagccctgat tcactccgtg aaaaaatctt tggcggacta
     5701 cggcgacaaa ctcgacgctg ccgaaaaaga aaaaatcgaa gccgcgctga aagaagccga
     5761 agaagccgtg aaaggcgacg acaaagccgc catcgatgcc aaagccgaag cactgggcac
     5821 agccagccaa aaactgggcg aaatggttta cgctcaagca caagctgaag cccaagcagg
     5881 cgaaagcgaa caagccaatg cttctgcaaa gaaagacgat gatgtcgtag atgccgactt
     5941 tgaagaagta aaagacgaca aaaaataatt gatgccgtct gaaaaaagcg cgaaccgttt
     6001 gattcgcgct tttttcaatt gagataaaag accatagcat aacagaggtt ccaagttcat
     6061 ctaccgtaat attcccaaac ccaagttcca actgttgtat cggttctctg gaaatttttt
     6121 atatagtgga ttaaatttaa accagtacag cgttgcctcg ccttagctca aagagaacga
     6181 ttctctaagg tgctgaagca ccaagtgaat cggttc
//
LOCUS       DAXIDM010000106         6210 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000106 DAXIDM010000000
VERSION     DAXIDM010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6210
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.106"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            278..724
                     /gene="yciA"
                     /locus_tag="ACFOAE_001724"
     CDS             278..724
                     /gene="yciA"
                     /locus_tag="ACFOAE_001724"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HFC6885167.1"
                     /translation="MQHEEGNRQRPQGELLLRTVAMPRDTNPNQDIFGGWIMSQMDLG
                     GGILAAEIARGRIVTVAVQEMNFIRPVKVGNVVCCYGHCVRVGNTSLQLKVEVWVKTL
                     MNDCVTEDRHLVTEAVFTYVAIDAEGNPRPIPKEGNPKLAGLLPTP"
     gene            complement(775..1596)
                     /locus_tag="ACFOAE_001725"
     CDS             complement(775..1596)
                     /locus_tag="ACFOAE_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFC6885168.1"
                     /translation="MAVLITGASAGFGEAMCRAFVGAGYRVIGAARRADRLQALADEL
                     GALFYPLEMDVSRRESVENALNGIPDEFSDIDCLINNAGLALGLDTADKADFEDWETM
                     IQTNVLGLTFLTRKILPQMVERGGGYVMNLGSIAGNYAYAGSNVYGATKAFVRQFSLN
                     LRAELADKNIRVTNIEPGLCGNTEFSNVRFKGDDEKAAGVYEGVEFIRPEDIAETALW
                     LYRRPAHMNVNTIEIMPVAQTFAGMKVIKKAVPEVREDFEKQSMSLFSRIRSWFK"
     gene            1715..2173
                     /locus_tag="ACFOAE_001726"
     CDS             1715..2173
                     /locus_tag="ACFOAE_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c"
                     /protein_id="HFC6885169.1"
                     /translation="MKTQISLAAAAITLLLSACGGSGIPSQPKGEISENRTAAFKSMM
                     PEFTRMGKMVKDEEPYDVEKFKQAAAAFAESSKKPFTLFESDPQGNGRALPAVWSDGA
                     KFEAEKTKFAAAVEKLNAAAQTGKLDEIKAAYGETGASCKSCHDSFRAPE"
     gene            complement(2337..3452)
                     /gene="lst"
                     /locus_tag="ACFOAE_001727"
     CDS             complement(2337..3452)
                     /gene="lst"
                     /locus_tag="ACFOAE_001727"
                     /EC_number="2.4.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyllactosaminide
                     alpha-2,3-sialyltransferase"
                     /protein_id="HFC6885170.1"
                     /translation="MGLKKACLTVLCLIVFCFGIFYTFDRVNQGERNAVSLLKDKLFN
                     EEGEPVNLIFCYTILQMKVAERIMAQHPGERFYVVLMSENRNEKYDYYFNQIKDKAER
                     AYFFHLPYGLNKSFNFIPTMAELKVKSMLLPKVKRIYLASLEKVSIAAFLSTYPDAEI
                     KTFDDGTINLIQSSSYLGDEFSVNGTIKRNFARMMIGDWSIAKTRNASDEHYTIFKGL
                     KNIMDDGRRKMTYLPLFDASELKAGDETGGTVRILLGSPDKEMKEISEKAAKNFNIQY
                     VAPHPRQTYGLSGVTTLNSPYVIEDYILREIKKNPHTRYEIYTFFSGAALTMKDFPNV
                     HVYALKPASLPEDYWLKPVYALFTQSGIPILTFDDKD"
     gene            3680..3820
                     /locus_tag="ACFOAE_001728"
     CDS             3680..3820
                     /locus_tag="ACFOAE_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/arginine repetitive matrix 2"
                     /protein_id="HFC6885171.1"
                     /translation="MPPHIRHSTSDTAAKSGKTISPFLSRRRVQTRQDRTKREQSRQN
                     MP"
     gene            3887..6112
                     /locus_tag="ACFOAE_001729"
     CDS             3887..6112
                     /locus_tag="ACFOAE_001729"
                     /EC_number="1.1.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003707467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HFC6885172.1"
                     /translation="MTQKSTIIYTHTDEAPALATQSLLPIVQAFARHADIDVKTADIS
                     LSGRILAAFPEYLTEAQRVPDTLAELGELVKQPDANVIKLPNISASVPQLTAAIKELQ
                     SKGFAVPDYPADPQTDEEKAVRERYDRIKGSAVNPVLREGNSDRRAPKAVKNFAKKNP
                     HSMGAWTKDSKTHVATMQSGDFFHNEQSVTVPEATSVSIVFTDKQGNKKELRAPVALK
                     AGEIIDATVMSKKALLAFLAEQVKDAKAKGVLFSLHMKATMMKVSDPIIFGHAVKVFF
                     APVFEKFGGKLAAAGVSVNNGFGNLLANLDKLDADTRAAVEAEIAAVYAANPDLAMVD
                     SDKGITNLHVPSDVIVDASMPAMIRNSGRMWDKNGKAQDTKAVIPDSSYAGVYQATID
                     FCREHGAFDPTTMGTVPNVGLMAQAAEEYGSHNKTFEIEADGQVQVIDAEGKVLMQHD
                     VEAGDIWRMCQTKDAPVKDWVQLAVNRARLSNTPAVFWLDENRPHDKSLLAKVKAYLA
                     ELDTNGLDIRVLAPEEAAKFSLGRLKNGEDTISVTGNVLRDYLTDLFPILELGTSAKM
                     LSIVPLMNGGGMFETGAGGSAPKHVQQFLEENHLRWDSLGEFLALAVSFEHLAQKTGN
                     AKAQVLADTLDAATEKLLLNDKSPKRKAGELDNRGSHFYLTLYWAQELAAQDKDAELK
                     AAFTPLAAALTADEAKIVAELSAVQGKAANIGGYYAANPEKAAQVMRPSVTFNQALNA
                     L"
BASE COUNT         1663 a         1805 c         1396 g         1346 t
ORIGIN      
        1 cgcgttctag attcccactt tcgtgggaat gacggttcag ttgcgtaggg ctgggtcgtc
       61 gaaaggggcg gattcgatgg actcaatgaa aacggtagaa atgttggatt gatggaaatg
      121 gcggactgaa gtccacccta cagccccgcc ctacaatacg ccttgcgaat ctgtccctcg
      181 cccgcccttg tatatctcaa atgggttaaa ctacgcactt cccgtttcgg gcaggggtgc
      241 aagtccgatt tatatttcaa taaaacaagg aaaaatgatg cagcacgaag aaggcaaccg
      301 ccaacgccct caaggcgaac tgctcctgcg taccgtcgct atgccgcgcg ataccaatcc
      361 caaccaagac attttcggcg gctggattat gtcgcagatg gatttgggcg gcggcatatt
      421 ggcggcggaa atcgcgcggg gacgcatcgt taccgtcgcc gttcaggaaa tgaactttat
      481 ccgcccggtc aaggtcggca acgtcgtctg ctgctacggg cattgcgtcc gcgtgggcaa
      541 tacttccctc cagcttaaag tcgaagtctg ggtgaaaact ttgatgaacg attgcgttac
      601 cgaagaccgc cacctcgtaa ccgaagccgt gttcacttat gtcgccatcg atgcggaagg
      661 caatccgcgc ccgattccga aagaaggcaa ccccaaattg gcgggcttat tgcctactcc
      721 gtaaaaatac ccgtaaaaat gccgtctgaa actgtcttca gacggcattc cgcatcattt
      781 gaaccaagac ctgatgcggg aaaacagcga catactttgt ttttcaaagt cttcccgcac
      841 ttcgggcacg gcttttttta tcactttcat tcctgcaaaa gtctgcgcca cgggcataat
      901 ttcaatcgtg ttcacattca tatgcgccgg ccggcggtac agccacaatg cggtttccgc
      961 aatatcttct gggcggataa attccacacc ctcatacacg cctgctgcct tctcgtcatc
     1021 gcctttgaag cgcacgttgg aaaactccgt attgccgcac aaacccggct cgatattggt
     1081 aacgcggatg ttcttatccg ccaactccgc gcgcaaattc aggctgaact ggcgcacaaa
     1141 cgccttggtc gccccgtaaa cgttgctgcc ggcataagca taattgcctg caatcgaacc
     1201 caaattcatc acataaccgc cgccgcgttc caccatttgc ggcaaaattt tgcgcgtcag
     1261 gaacgtcaaa cccaaaacat tggtttgaat catcgtttcc caatcttcaa aatccgcctt
     1321 gtccgccgtg tccagaccca aagccagccc ggcattgttg atgaggcagt cgatgtcgga
     1381 aaattcatcg gggatgccgt ttaaggcgtt ttccaccgac tcgcggcgcg acacgtccat
     1441 ttccaaaggg taaaacaaag cacccaattc atccgccaag gcctgaagcc tgtccgcacg
     1501 acgcgccgca ccgataacgc ggtatcccgc cccgacaaac gcgcggcaca tcgcttcgcc
     1561 gaatcctgcc gaagcaccgg taattaaaac agccattgtt tttcctttct ttctcgtttc
     1621 ccaaacctgt ttcaggtatc ataacgctct tcagacggca tcgcgccggc tgaaaatgac
     1681 aacaaccata ccaccacgac aggacacatt caatatgaaa acccaaatca gccttgctgc
     1741 tgccgccatc acactgctcc tttccgcctg cggaggcagc ggaatacctt cccaacccaa
     1801 aggcgaaatt tccgaaaacc gcaccgccgc gttcaaatcc atgatgcccg aattcacacg
     1861 catgggcaaa atggtcaaag acgaagaacc ttacgatgtc gaaaaattca aacaggctgc
     1921 cgcggcgttt gccgaaagca gcaagaaacc gttcacactt tttgagtccg atccgcaagg
     1981 caacggccgc gccctgcccg ccgtttggtc ggatggtgca aaatttgaag ccgaaaaaac
     2041 aaaattcgcc gccgccgtcg aaaaactcaa cgccgcagca caaaccggca aactggatga
     2101 aatcaaagcc gcctacggcg aaaccggcgc aagctgcaaa tcctgccacg acagtttccg
     2161 cgcgcccgaa taacatccaa aacaaaacaa tgccgtctga agccttcaga cggcattttc
     2221 tttgccattt caccaagcgc aaagcaatca aaaattatcg ttaattcaaa aaatacgcca
     2281 tatcctgatt tttgccttac ttactccgcc attttctatt tttatttgct atgcgattaa
     2341 tctttatcgt caaatgtcaa aatcgggatg ccggattggg taaacagggc atacaccggc
     2401 ttgagccaat aatcttccgg aagggaagcc ggtttcaatg cgtaaacgtg cacattggga
     2461 aaatccttca tcgtcaacgc cgcgccgctg aaaaaggtat aaatttcata cctcgtatgc
     2521 gggtttttct taatctcgcg caaaatatag tcttcgatga catagggcga atttaatgtg
     2581 gttacgccgg aaagcccgta ggtttggcgg gggtgcggtg cgacatattg tatgttgaag
     2641 ttttttgccg ccttttccga aatttccttc atctccttgt cgggcgaacc caaaagtatc
     2701 cgcaccgtgc cgcccgtttc gtcccccgcc ttcagttcgg acgcatcgaa cagcggcagg
     2761 taagtcatct tgcggcggcc gtcgtccata atgtttttca aacccttgaa tatcgtgtaa
     2821 tgctcgtcgg aagcattgcg ggttttggcg atgctccaat ctccgatcat catccgggca
     2881 aaattccgct tgatcgtccc gtttacagaa aactcatcgc ccaaatagct gctgctttga
     2941 attaaattga ttgtcccgtc gtcaaaggtt ttgatttccg catccgggta agtgctcaaa
     3001 aaggcggcaa tgctgacttt ttccaaactt gccaaataaa tccgcttgac tttcggcagc
     3061 agcatcgact ttaccttcag ctccgccatc gtcggaatga aattaaacga tttgttcaaa
     3121 ccgtagggca ggtggaaaaa atacgcccgc tccgccttat cctttatctg attgaaataa
     3181 taatcgtatt tttcattcct gttttcagac atcagcacca cataaaaccg ctcccccgga
     3241 tgctgcgcca taatcctttc tgccaccttc atctgcaata tggtatagca gaaaatcaga
     3301 ttgaccggtt ccccctcttc attgaagagt ttgtccttca gcagggaaac cgcattcctt
     3361 tccccctgat ttacccggtc aaatgtataa aatatcccga aacaaaaaac aatcaggcac
     3421 aacacggtca aacaagcctt tttcaagccc atatccctaa aactccattc cgacaaattg
     3481 aacatacgcc ccgagtgtcc cgggacggaa aaatgcggaa ttttagcaga tattccgaca
     3541 gttaccgaat attatagtga tttaaattta aatcaggaca aggcgacgaa gccgcagaca
     3601 gtacaagcag tacgacaagg cgaggcaacg ctgtactggt ttaaatttaa accactataa
     3661 aatcaatttc accgaaaata tgccgccgca catcaggcac agcacctccg acaccgccgc
     3721 caaaagcggg aaaaccattt cccccttcct ttcacgtcgc cgcgttcaaa cacgccaaga
     3781 tcgaacaaag cgcgaacaaa gccgccaaaa tatgccataa tagccacgca cattccccgc
     3841 gcaatgtgtt ccaaaagaaa aaaccaacct acaagagaat aatcctatga ctcaaaaatc
     3901 caccattatt tatacccata ccgacgaagc ccccgcgctg gcgacccaat cgctgctgcc
     3961 gattgtgcag gcttttgccc gccacgccga tattgatgtc aaaactgccg acatttccct
     4021 gtccggccgt attttggcgg cattccccga atatctgacc gaagcgcaac gcgtacccga
     4081 cacgcttgcc gaattgggcg aactggtaaa acaacccgat gcaaacgtaa tcaaactgcc
     4141 gaacatcagc gcatccgtac cgcaactgac cgccgcgatt aaagaattgc agtctaaagg
     4201 ctttgccgtt cccgattatc ctgccgaccc gcaaaccgat gaagaaaaag ccgtgcgcga
     4261 acgctacgac cgcatcaaag gcagcgcggt aaaccctgtc ctgcgtgaag gcaactccga
     4321 ccgtcgcgcc cccaaagcgg tgaaaaactt tgccaaaaaa aatccgcaca gcatgggcgc
     4381 atggacaaaa gactccaaaa cccacgttgc caccatgcaa agcggcgact ttttccataa
     4441 cgaacaatcc gttaccgtac ctgaagcgac ttccgtatcc atcgtgttca ccgacaaaca
     4501 aggcaataaa aaagagctgc gcgcgcctgt tgccctgaaa gccggcgaaa tcatcgacgc
     4561 aaccgtgatg agcaaaaaag ccctgctcgc cttccttgcc gaacaagtga aagacgcgaa
     4621 ggcaaaaggc gtattgttct cactgcatat gaaagccacg atgatgaaag tgtccgaccc
     4681 gattatcttc ggacacgccg tcaaagtgtt cttcgcgcct gtatttgaaa aattcggcgg
     4741 caaactggct gccgcaggtg tcagcgtcaa caacggcttc ggcaacctgc ttgccaatct
     4801 ggacaaactg gatgcggaca cccgcgccgc cgtcgaagct gaaatcgccg ccgtttacgc
     4861 cgccaaccct gatttggcga tggttgattc cgacaaaggc atcaccaacc tgcacgttcc
     4921 cagcgatgtc atcgtcgatg cctctatgcc tgcgatgatt cgcaattccg gccgtatgtg
     4981 ggacaaaaac ggcaaagcgc aagacaccaa agccgtgatt cccgacagca gctatgccgg
     5041 cgtttaccaa gcaaccatcg acttctgccg cgaacacggc gcgttcgatc cgacaacaat
     5101 gggtactgtt cccaatgtcg gtttgatggc gcaagcggcg gaagaatacg gctcgcacaa
     5161 caaaaccttt gaaatcgaag ccgacggtca ggttcaagtc attgatgcgg aaggaaaagt
     5221 cctgatgcag cacgacgttg aagcaggcga catctggcgt atgtgccaaa ccaaagacgc
     5281 tccggtcaaa gactgggtgc aactcgccgt caaccgcgcc cgcctgagca acacgcctgc
     5341 cgtgttctgg ctcgatgaaa accgtccgca cgacaagagc ctgctcgcca aggttaaagc
     5401 ctaccttgcc gaactggata ccaatggcct cgacatccgc gtcctcgctc ctgaagaagc
     5461 cgccaagttc agcttgggtc gtctgaaaaa cggcgaagac accatctccg taaccggtaa
     5521 tgtcttgcgc gactacctga ccgacttgtt cccaattttg gaactcggca caagcgcgaa
     5581 aatgctgtct atcgttccat tgatgaacgg cggcggtatg tttgaaaccg gcgcgggcgg
     5641 ttctgcaccg aaacatgttc aacaattcct cgaagaaaac catttgcgct gggactcgct
     5701 gggcgaattc ctcgcactcg ccgtatcgtt tgaacatttg gcgcaaaaaa ctggcaatgc
     5761 caaagcccaa gtcctcgccg acactttgga tgcagccacc gaaaaactgc tgttgaacga
     5821 caaatcgcct aaacgtaaag ccggcgaact cgacaaccgc ggcagccatt tctacctcac
     5881 cctctactgg gcgcaagaat tggcggcgca agacaaagat gccgaactga aagccgcatt
     5941 tacgccattg gcagccgctt tgaccgccga cgaagcgaaa atcgttgccg agctttccgc
     6001 cgtacaaggc aaagcggcca acatcggcgg ctactacgcc gccaatcctg aaaaagccgc
     6061 acaagtgatg cgtccgagcg taacctttaa tcaggcacta aacgccttat aagcacaaag
     6121 gtaaaaatgc cgtctgaaca ttcgtcgttc agacggcatt agttatccct atctgcctga
     6181 ttatgattaa acgccgcacc cattggatat
//
LOCUS       DAXIDM010000107         6069 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000107 DAXIDM010000000
VERSION     DAXIDM010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 6069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6069
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.107"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            25..408
                     /locus_tag="ACFOAE_001730"
     CDS             25..408
                     /locus_tag="ACFOAE_001730"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004143 - ATP-dependent diacylglycerol
                     kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFC6885173.1"
                     /translation="MEPSSYAAEKKGKGGIRRVINAFGYSIDGIAAAYRYEAAFRQVL
                     WLNVLLVCAAFFWVSETAVRLPLIIASFVSVIVELFNTAVEAAVDHTSTEKHELAKLA
                     KDAGSAAQLFAMLMLAAVWLSALFG"
     gene            545..1018
                     /locus_tag="ACFOAE_001731"
     CDS             545..1018
                     /locus_tag="ACFOAE_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016531 - copper chaperone activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone PCu(A)C"
                     /protein_id="HFC6885174.1"
                     /translation="MKKLLAAVMMAGLAGAVSAAGVHVEDGWARTTVEGMKIGGAFMK
                     IHNDEAKQDFLLGGSSPVADRVEVHTHINDNGVMRMREVKGGVPLEAKSVTELKPGSY
                     HVMFMGLKKQLKEGDKIPVTLKFKNAKAQTVQLEVKTAPMPAMNHGHHHGEAHQH"
     gene            1144..2247
                     /gene="mnmA"
                     /locus_tag="ACFOAE_001732"
     CDS             1144..2247
                     /gene="mnmA"
                     /locus_tag="ACFOAE_001732"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFC6885175.1"
                     /translation="MNTTANPSNIIVGLSGGVDSSVTAALLKQQGYQVRGVFMQNWED
                     DDNDEYCSIKQDSFDAIAVADIVGIDIDIVNFAAQYKDKVFAYFLQEYSAGRTPNPDV
                     LCNAEIKFKCFLDYAVGQGADTIATGHYARKEVRNGVHYLLKGLDRNKDQSYFLYRLK
                     PFQLERAIFPLGGLEKPEVRRLAAEFKLPTAAKKDSTGICFIGERPFREFLQKYLPTD
                     NGKMVTPEGKTVGEHVGLMFYTLGQRKGLGIGGAGEPWFVAAKDLTKNELIVVQGHDH
                     PLLYTRSLVMNDLSFTLPERPKAGRYTCKTRYRMADAPCELRYLDEETAELVFDEPQW
                     AVTPGQSAVLYDGDICLGGGIIQTTDKPVIITR"
     gene            2319..3989
                     /locus_tag="ACFOAE_001733"
     CDS             2319..3989
                     /locus_tag="ACFOAE_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFC6885176.1"
                     /translation="MEKIWLDSYEQGVNAEIDITQYGSVSDVFCQSVKKFAGQPAFQN
                     MGKTLTYAETGKLATDFASYLQNVLKLPRGERVAIMMPNVLQYPIALFGILQAGLVAV
                     NTNPLYTPRELEHQLKDSGAAAIIVLENFANTLELVLPRTQIKHVIVASVGEMFGLLK
                     GSLINFIIRKIKKMVPEYRIRETVSFQTALKEGAKHVFQPVALNREDTALLQYTGGTT
                     GVAKGAVLSHGNICANMLQAKEWIKNQLREGKETVIAALPLYHIFALTVNLMIFANAG
                     SKIVLITNPRDMKGFIGELKKQRVNVFIGVNTLFNAMVNRPDFAEVDFSELRLTLGGG
                     MATQKAVAEKWKKITGTPIVEAYGLTEASPGVCCNPLNIESYSGSIGLPVSSTEVELR
                     DANGKEVPVGQPGELWVKGPQVMQGYWNRPEETAKAIDARGFLETGDIAVMDEKGWLK
                     LVDRKKDLVVVSGFNVYPNEIEEVIAHHGKVMEVACIGVPDEKTGEALKVFVVKKDPS
                     LTKEELIAFCRTELTAYKVPKNIEFRDELPKSNVGKILRRELRQSTGK"
     gene            4101..5735
                     /locus_tag="ACFOAE_001734"
     CDS             4101..5735
                     /locus_tag="ACFOAE_001734"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFC6885177.1"
                     /translation="MTKFIFVTGGVVSSLGKGIAAASIAAILESRGLNVTMLKLDPYI
                     NVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFIDSTMTRRNSFSTGQVYENVIAKE
                     RRGDYLGGTVQVIPHITDEIKRRIHEGAAGYDVAIVEIGGTVGDIESLPFLEAIRQMR
                     SQLGRSNTLFAHLSYVPYIAAAGEIKTKPTQHTVKEMLSIGLQPDILICRMDREMPAD
                     ERRKIALFCNVEERAIVGSYDVDSIYECPEMLHDQGIDNIITEQLQLNVQQADLTAWK
                     KIVHAIQNPKHTVKIAMVGKYVDLTESYKSLIEALKHAGIHTETDVQITFVDSESIEK
                     NNGDVSMLKDMDAILVPGGFGSRGVEGKIAAVRYARENNVPYLGICLGMQIALIEYAR
                     DVAGLKGANSTEFDLKCAAPVVALIDEWQTADGSVETRDESADLGGTMRLGAQEVELK
                     AGSLAAKIYGSEHIRERHRHRYEVNNNYVPTLEQAGLVIGGVSAGRERLVETIELPNH
                     PWFFACQFHPEFTSNPRKGHPLFTAFVKAALNNKKA"
     gene            5963..>6069
                     /locus_tag="ACFOAE_001735"
     CDS             5963..>6069
                     /locus_tag="ACFOAE_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC6885178.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIE"
BASE COUNT         1585 a         1647 c         1529 g         1308 t
ORIGIN      
        1 tgagaacatt ttgaaaggat accgatggaa ccttcttctt acgcggcaga aaaaaaaggc
       61 aaaggcggca tcaggcgcgt cattaacgca ttcggctatt cgatagacgg catcgccgcc
      121 gcctaccgtt acgaagcggc attccgtcag gttttgtggc tgaacgtact gctggtgtgc
      181 gcggcatttt tttgggtttc cgaaaccgcc gtccgcctgc cgttgattat cgcgtctttt
      241 gtgtcggtca ttgtcgaact gttcaacacc gccgtcgaag ctgccgtcga tcatacttcg
      301 accgaaaaac acgagctggc caaactcgcc aaagacgcag gttctgccgc acaattgttc
      361 gcgatgctga tgttggcggc ggtttggctg tctgccctgt tcgggtaaaa cgcttgcagc
      421 aggatttgta accctttagg attagtatgt agtatttatt attcgcttaa tctatatcaa
      481 atttctgaac ggtatttgtt tgtaagatga gcgcatcctc gtttgacatt taaggagtag
      541 aaagatgaaa aaactattgg cggccgtgat gatggcaggt ttggcaggcg cggtttccgc
      601 cgccggagtc cacgttgagg acggctgggc gcgcaccacc gtcgaaggta tgaaaatagg
      661 cggcgcgttc atgaaaatcc acaacgacga agccaaacaa gactttttgc tcggcggaag
      721 cagccccgtt gccgaccgcg tcgaagtgca tacccacatc aacgacaacg gtgtgatgcg
      781 gatgcgcgaa gtcaaaggcg gcgtgccttt ggaggcgaaa tccgttaccg aactcaagcc
      841 cggcagctat cacgtgatgt ttatgggttt gaaaaaacaa ttaaaagagg gcgacaagat
      901 tcccgttacc ctgaaattta aaaacgccaa agcgcaaacc gtccaactgg aagtcaaaac
      961 cgcgccgatg ccggcaatga accacggtca tcaccacggc gaagcgcatc agcactaatc
     1021 tgctgaaaat atttgaaatg ccgtctgaaa aagcccgggc tttcagacgg catttttatg
     1081 actgccttta aaatgtgtta aaatccgcct ttaaaaaccg ccgtttccaa ccatattcta
     1141 cgcatgaata cgacagcaaa cccttccaat atcatcgtcg ggctctccgg cggtgtcgat
     1201 tcttccgtaa ccgccgccct gctcaagcag cagggttatc aagtgcgcgg tgtgttcatg
     1261 cagaactggg aagacgacga caacgacgaa tattgcagca tcaaacagga ttcgtttgat
     1321 gccatcgccg ttgccgatat tgtcggcatc gacatcgaca tcgttaattt cgccgcgcaa
     1381 tataaagaca aagtctttgc ttattttctt caggaataca gtgcggggcg cacgccgaat
     1441 cccgatgtgt tgtgcaacgc cgaaatcaaa ttcaaatgct ttttggatta cgccgtaggg
     1501 cagggcgcgg ataccatcgc caccggacac tatgcgcgca aagaagtccg caacggcgtg
     1561 cattacctgc tcaaaggttt ggatcgaaac aaagaccaaa gctatttcct ctaccgcctc
     1621 aagcctttcc aactcgagcg cgcgattttt ccgttgggcg gtttggaaaa acccgaagtc
     1681 cgccgccttg ccgccgagtt caaactgccg actgccgcca aaaaagacag cacgggcatc
     1741 tgcttcatcg gcgaacgccc gtttcgcgag tttctgcaaa aatacctgcc gaccgacaac
     1801 ggtaaaatgg ttacgcccga agggaaaacc gtcggcgaac acgtcgggct gatgttctac
     1861 acgctcggac agcgcaaagg tttgggcatc ggcggcgcgg gcgaaccgtg gtttgttgcg
     1921 gctaaagatt tgacgaaaaa cgaactgatt gtcgtgcaag gacacgacca tccgctgctc
     1981 tatacccgca gccttgtgat gaacgatttg agtttcacgc ttcccgaacg cccgaaggca
     2041 ggacgctata cctgcaaaac gcgttaccgt atggcggacg cgccttgtga gttgcgctat
     2101 ttggatgaag aaaccgccga gctggtgttt gacgaaccgc aatgggcggt tacgccgggc
     2161 cagtctgccg tgctgtacga cggcgacatc tgtttgggcg gcggcatcat tcaaacgacc
     2221 gacaagcctg tcatcatcac acgataaaac ttatgccgtc tgaaacagtt ttcagacggc
     2281 attgttccgc tcaattccac tttaaaagac cgatacctat ggaaaaaatc tggttagaca
     2341 gttacgaaca gggcgtgaat gccgaaatcg acatcacgca atacggttcc gtcagcgatg
     2401 tattttgcca aagtgtcaag aaatttgccg gccaacctgc ttttcaaaac atgggcaaaa
     2461 cgctgactta tgccgaaacc ggcaaactgg cgaccgattt cgcctcttat ctgcaaaacg
     2521 tcctcaagct gccgcgcggc gaacgtgttg ccattatgat gccgaacgta ttgcaatatc
     2581 cgattgccct tttcggtatt ttgcaggcag gtttggtagc ggtgaacacc aatccgctct
     2641 ataccccgcg cgagctggag catcagttga aagacagcgg cgcggccgcc atcatcgttt
     2701 tggaaaattt cgccaacacg ctggagctgg tgctgccgcg cacgcagatc aaacacgtca
     2761 tcgtcgcctc tgtcggcgaa atgttcgggc tgcttaaagg ttcgctgatc aatttcatca
     2821 tccggaaaat caagaaaatg gtgcccgaat accgtattcg ggaaaccgtt tcctttcaga
     2881 cggcattgaa agaaggggcg aagcacgttt tccaacctgt cgcattaaac cgcgaagata
     2941 ccgcgctgtt gcaatacacg ggcggcacga caggtgttgc caaaggggcg gtgctgagtc
     3001 acggcaacat ctgcgccaat atgcttcagg caaaagaatg gattaaaaac cagttgcgcg
     3061 agggcaaaga aaccgttatc gccgccctgc cgctgtatca tatttttgcc ttaaccgtga
     3121 atctgatgat ttttgccaat gccggctcga aaattgtcct gattaccaac ccgcgcgata
     3181 tgaaaggctt tatcggcgaa ctgaaaaaac agcgggttaa tgtatttatc ggcgtaaaca
     3241 cgctgtttaa cgcgatggtt aaccggcccg attttgccga agtcgatttt tcagaattgc
     3301 ggctgacttt gggcggcggt atggcgaccc aaaaagccgt tgccgaaaaa tggaaaaaaa
     3361 tcaccggcac gcccatcgtc gaagcctacg gtttgaccga agccagcccc ggcgtgtgct
     3421 gcaacccctt aaacatcgaa tcatacagcg gcagcatcgg tttgcccgtc tcgtccaccg
     3481 aagtcgaact gcgcgacgca aacggcaaag aagtccccgt cgggcagccg ggcgaattgt
     3541 gggtaaaagg ccctcaagtg atgcaaggct actggaaccg ccccgaagaa accgccaaag
     3601 ccatagacgc gcgcggcttc ttggaaaccg gcgatattgc cgtcatggac gaaaaaggct
     3661 ggttgaagct ggtcgatcgt aagaaagacc tcgtcgttgt ttccggattc aatgtttatc
     3721 cgaacgaaat cgaggaagtc atcgcgcatc acggcaaagt catggaagtc gcctgtatcg
     3781 gcgttcccga cgaaaaaacc ggcgaggcac tcaaagtatt cgtcgtcaaa aaagacccgt
     3841 cattgaccaa agaagaactt atcgcctttt gccgcaccga attaaccgca tataaagtac
     3901 cgaaaaatat cgaattccgc gacgagttgc ccaagtccaa cgtcggcaaa atcctgcgcc
     3961 gcgagttgcg gcaaagtacc gggaaataaa gaaaagatgc cgtctgaaaa cagccgtcca
     4021 ccgttcagac ggcatccgtc cgtttgccag aaccgcgcgc ttcacgttaa aatcacgcat
     4081 tccaacatgg gtattccatc atgaccaaat tcattttcgt aaccggcggc gttgtctcct
     4141 cactgggtaa aggtatcgcc gccgcttcta ttgccgccat cctcgaatcg cgcggcttga
     4201 acgttaccat gctcaagctc gatccttata tcaacgtcga tcccggcacg atgagcccgt
     4261 tccaacacgg cgaagtgttc gtaaccgacg acggcgcgga aaccgacctc gacttgggac
     4321 actacgaacg gtttatcgat tccacgatga cccgccgcaa cagcttcagc acggggcagg
     4381 tgtacgaaaa cgtcatcgcc aaagaacgac ggggcgacta cctcggcggc acggttcaag
     4441 tcattccgca cattaccgac gaaatcaaac gccgcatcca cgaaggcgcg gcaggttatg
     4501 atgtggcgat tgtcgaaatc ggcggcacgg tcggcgacat cgaatcgctg ccgtttttgg
     4561 aagccatccg ccaaatgcga agccagttgg gacgcagcaa caccctgttc gcccacttga
     4621 gctacgtccc ctacatcgcc gccgccggcg aaatcaaaac caaaccgacc cagcatactg
     4681 ttaaagaaat gttgagcatc ggtttgcaac cggacatcct gatctgccgt atggacagag
     4741 aaatgcctgc ggacgagcgc cgtaagattg cattgttctg taacgttgaa gaacgtgcca
     4801 tcgtgggcag ttacgacgtg gacagcatct acgaatgccc cgaaatgctg cacgaccaag
     4861 gcatcgataa catcattacc gagcagttgc agcttaatgt gcagcaggcg gatttgaccg
     4921 cgtggaaaaa aatcgtccac gccatccaaa acccgaaaca caccgtcaaa atcgccatgg
     4981 tcggcaaata cgtcgatttg accgagtcct acaaatcgct gatcgaagcc ttgaaacacg
     5041 caggcattca caccgaaacc gacgtacaaa ttacctttgt tgacagcgaa agcatcgaga
     5101 aaaacaacgg cgacgtttct atgcttaaag atatggacgc catcctcgtt cccggcggtt
     5161 tcggttcgcg cggcgtggaa ggcaaaatcg ccgctgtgcg ctatgcccgc gaaaacaacg
     5221 tgccatactt gggcatctgc ctcggtatgc agattgcgct gatcgaatac gcccgcgacg
     5281 tggcaggttt gaaaggtgcg aattccaccg agttcgacct caaatgcgcc gcccccgtcg
     5341 ttgccctgat tgacgaatgg caaactgccg acggcagcgt cgaaacccgc gacgaatccg
     5401 ccgatttggg cggcaccatg cgtttgggcg cgcaagaagt cgaattgaaa gcaggcagcc
     5461 tcgccgccaa aatctacggc agcgaacaca tccgcgaacg ccaccgccac cgctacgaag
     5521 tcaacaacaa ctacgttcct acgctggaac aggcaggttt ggtcatcggc ggcgtatccg
     5581 ccggacgcga acgcttggtc gaaaccatcg aactgccgaa ccatccttgg ttcttcgcct
     5641 gccagttcca ccccgagttt acctccaatc cgcgcaaagg gcatcctttg ttcaccgcgt
     5701 ttgtcaaagc tgcgttgaac aataaaaaag cctgataaag cgttacttga tgatcaaaat
     5761 gccgtctgaa agcctgaatg aagactttca gacggcattt ttgcaaatcg gggatcataa
     5821 aagccatcaa tttaattttt atggttttat ctaatattga ccaactgaat attgttaagc
     5881 ggggcgtgaa actcaagttg agacctttgc aaaattcccc aaaatcccct aaattcccac
     5941 caagacattt aggagatttc tcatgagcac cttctttcag caaaccgcac aagccatgat
     6001 tgccaaacac atcgaccgct tcccactatt gaagttggac caggtgattg attggcagcc
     6061 gatcgaaca
//
LOCUS       DAXIDM010000108         5990 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000108 DAXIDM010000000
VERSION     DAXIDM010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5990
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.108"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            45..458
                     /locus_tag="ACFOAE_001736"
     CDS             45..458
                     /locus_tag="ACFOAE_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqaA family protein"
                     /protein_id="HFC6885179.1"
                     /translation="MMPAYAYAALAFSAFTSATLLPGTSEAAFALFVHRFPEHAYGAL
                     LCAGLANGLGSMVSYWMGRLLPSRKMPSEKTLNLMRRFGIWLLAFAWLPVVGDALPLA
                     AGWLRLNPWTSGLMLVIGKTARYAFILWGMQYYAA"
     gene            504..1133
                     /gene="nth"
                     /locus_tag="ACFOAE_001737"
     CDS             504..1133
                     /gene="nth"
                     /locus_tag="ACFOAE_001737"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFC6885180.1"
                     /translation="MNRQIRQEIFERFRAANPHPTTELNFNSPFELLIAVLLSAQATD
                     VGVNKATAKLFPVADTPQAMLDLGLDGVMEYTKTIGLYKTKSKHIMQTCRILLEKYKG
                     EVPEDREALESLPGVGRKTANVVLNTAFGHPVMAVDTHIFRVSNRTKIAPGKDVREVE
                     DKLMRFIPKEFLMDAHHWLILHGRYTCKALKPQCQTCIINDLCEYPAKA"
     gene            1271..2770
                     /locus_tag="ACFOAE_001738"
     CDS             1271..2770
                     /locus_tag="ACFOAE_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegQ family serine endoprotease"
                     /protein_id="HFC6885181.1"
                     /translation="MFKKYQYLALAALCAASLAGCDKAGSFFGADKKEASFVERIEHT
                     KDDGSVSMLLPDFVQLVQSEGPAVVNIQAAPAPRTQNGSSNAETDSDPLADSDPFYEF
                     FKRLVPNMPEIPQEEADDGGLNFGSGFIISKDGYILTNTHVVTGMGSIKVLLNDKREY
                     TAKLIGSDVQSDVALLKIDATEELPVVKIGNPKDLKPGEWVAAIGAPFGFDNSVTAGI
                     VSAKGRSLPNESYTPFIQTDVAINPGNSGGPLFNLKGQVVGINSQIYSRSGGFMGISF
                     AIPIDVAMNVAEQLKNTGKVQRGQLGVIIQEVSYGLAQSFGLDKAGGALITKILPGSP
                     AERAGLQAGDIILSLNGEEIRSSGDLPVMVGAITPGKEVSLGVWRKGEEITIKVKLGN
                     AAEHTGASSKTDEAPYTEQQSGTFSVESAGITLQTHTDSSGGHLVVVRVSDAAERAGL
                     RRGDEILAVGQVPVNDEAGFRKAMDKAGKNVPLLIMRRGNTLFIALNLQ"
     gene            2971..4491
                     /locus_tag="ACFOAE_001739"
     CDS             2971..4491
                     /locus_tag="ACFOAE_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HFC6885182.1"
                     /translation="MQLIDYSHSFFSVVPPFLALALAVITRRVLLSLGIGILVGVAFL
                     VGGNPVDGLTHLKDMVVGLAWSDGDWSLGKPKILVFLILLGIFTSLLTYSGSNQAFAD
                     WAKRHIKNRRGAKMLTACLVFVTFIDDYFHSLAVGAIARPVTDKFKVSRTKLAYILDS
                     TAAPMCVLMPVSSWGASIIATLAGLLVTYKITEYTPMGTFVAMSLMNYYALFALIMVF
                     VVAWFSFDIGSMARFEQAALNEAHDETAVSDATKGRVYALIIPVLALIASTVSAMIYT
                     GAQASETFSILGAFENTDVNTSLVFGGTCGVLAVVLCTLGTIKTADYPKAVWQGAKSM
                     FGAIAILILAWLISTVVGEMHTGDYLSTLVAGNIHPGFLPVILFLLASVMAFATGTSW
                     GTFGIMLPIAAAMAVKVDPSLIIPCMSAVMAGAVCGDHCSPISDTTILSSTGARCNHI
                     DHVTSQLPYALTVAAAAASGYLALGLTKSALLGFGTTGIVLAVLIFLLKDKKRANA"
     gene            4548..5633
                     /gene="nagZ"
                     /locus_tag="ACFOAE_001740"
     CDS             4548..5633
                     /gene="nagZ"
                     /locus_tag="ACFOAE_001740"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HFC6885183.1"
                     /translation="MTVPHIPRGPVMADIAAFRLTEEEKQRLLDPAVGGIILFRRNFQ
                     NIEQLKTLTAEIKALRTPELIIAVDHEGGRVQRFIEGFTRLPAMSTLGEIWDKDGASA
                     AETAAGQVGRVLATELSACGIDLSFTPVLDLDWGNCPVIGNRSFHHNPEAVAHLALAL
                     QKGLAKGGMKSCGKHFPGHGFVEGDSHLVLPEDRRSLSELEAADLAPFHIMSREGMAA
                     VMPAHVVYPQVDTKPAGFSEIWLKQILRRDIGFKGVIFSDDLTMEGACGVGGLKERAR
                     ISFEAGCDIVLVCNRPDLVDELREDFRIPDNPALAQRWQYMANTLGSAAAQAVMQTAD
                     FQEAQAFVAGLASPQDTAGGVKVGEAF"
     gene            5861..5937
                     /locus_tag="ACFOAE_001741"
     tRNA            5861..5937
                     /locus_tag="ACFOAE_001741"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5895..5897,aa:Pro,seq:cgg)
BASE COUNT         1386 a         1815 c         1484 g         1305 t
ORIGIN      
        1 cgtacaatcc gtcgccgatt tttgcctgtt tgagactgtt tgcaatgatg cccgcctacg
       61 cctacgccgc gctcgctttt tccgccttca cttccgccac cctcctgccc ggcacatccg
      121 aagccgcctt tgccctgttc gtccaccgct ttcccgaaca cgcatacggc gcgttgctgt
      181 gcgccggcct tgccaacgga ttgggcagta tggtttccta ttggatgggg cgtttgctgc
      241 cctcccgaaa aatgccgtct gaaaaaacac tgaatctgat gcggcgtttc ggtatttggc
      301 tgcttgcgtt tgcctggctg cccgtcgtcg gcgacgcact gccgcttgcc gccggctggc
      361 tgcggttgaa tccgtggaca agcgggctga tgctggttat cggcaaaacg gcgcgttacg
      421 ccttcattct gtggggaatg caatattacg ccgcctaaac catacgttat aatgccgaac
      481 acacaaaccc accgtataaa aaaatgaaca gacaaatccg ccaagaaatc ttcgagcgtt
      541 tccgcgctgc caacccccat cctaccacag aactcaactt caactcccct ttcgagcttt
      601 taatcgccgt tttactgtcg gcacaggcaa ccgacgtcgg cgtaaacaaa gcgacggcga
      661 agctgtttcc ggttgccgat acgccgcagg cgatgctgga tttgggtttg gacggcgtga
      721 tggaatatac gaaaaccatc gggttgtata aaaccaagtc caaacacatc atgcagacct
      781 gccgcatcct gttggaaaaa tacaagggcg aagtgccgga agaccgcgag gctttggaat
      841 cgttgcctgg cgtggggcgc aaaacggcaa acgtggtatt gaacacggcg ttcggacacc
      901 ccgttatggc ggtcgatacg catattttcc gcgtgtccaa ccgaaccaaa atcgcccccg
      961 ggaaagatgt gcgcgaagtc gaagacaaac tgatgcgctt cattcctaaa gaatttctga
     1021 tggacgcgca ccactggctg attttgcacg gacgctacac ctgcaaggct ttaaagccgc
     1081 aatgccaaac ctgcatcatc aacgatttgt gcgaatatcc cgccaaagcc tgaccgccgc
     1141 cgtccttcaa aatgaaacgc ttgaaaattc ggacggacgt tgtagaattt caacctatgc
     1201 cgtctgaagc cgacaaaatg cgcttcagac ggcattaaag ccggtaccgg catccgacaa
     1261 aggacaaaac gtgttcaaaa aataccaata cctcgctttg gcagcactgt gtgccgcctc
     1321 gctggcaggc tgcgacaaag ccggcagctt tttcggtgcg gacaaaaaag aagcatcttt
     1381 cgtagaacgc atcgaacaca ccaaagacga cggcagcgtc agtatgctgc tgcccgactt
     1441 tgtccaactg gttcaaagcg aaggcccggc agtcgtcaat attcaggcag cccccgcccc
     1501 gcgcacccaa aacggcagca gcaatgccga aaccgattcc gacccgcttg ccgacagcga
     1561 cccgttctac gaatttttca aacgcctcgt cccgaacatg cccgaaatcc cccaagaaga
     1621 agcagatgac ggcggattga acttcggttc gggcttcatc atcagcaaag acggctatat
     1681 tctgaccaat acgcacgtcg ttaccggcat gggcagtatc aaagtcctgc tcaacgacaa
     1741 gcgcgaatat accgccaaac tcatcggttc ggatgtccaa tccgatgtcg cccttctgaa
     1801 aatcgacgca acggaagagc tgcccgtcgt caaaatcggc aatcccaaag atttgaaacc
     1861 gggcgaatgg gtcgccgcca tcggcgcgcc cttcggcttc gacaacagcg tgaccgccgg
     1921 catcgtgtcc gccaaaggca gaagcctgcc caacgaaagc tacacaccct tcatccaaac
     1981 cgacgttgcc atcaatccgg gcaactccgg cggcccgctg ttcaacttaa aaggacaggt
     2041 cgtcggcatc aactcgcaaa tatacagccg cagcggcgga ttcatgggca tttccttcgc
     2101 catcccgatt gacgttgcca tgaatgtcgc cgaacagctg aaaaacaccg gcaaagtcca
     2161 acgcggacaa ctgggcgtga ttattcaaga agtatcctac ggtttggcac aatcgttcgg
     2221 tttggacaaa gccggcggcg cattgattac caaaatcctt cccggcagcc ccgcagaacg
     2281 tgcaggcttg caggcaggcg acatcatact cagcctcaac ggagaagaaa tacgttcttc
     2341 cggcgacctt cccgttatgg tcggtgccat tacgccggga aaagaagtca gcctcggcgt
     2401 atggcgcaaa ggcgaagaaa tcacaatcaa agtcaagctg ggcaacgccg ccgagcatac
     2461 cggcgcatca tccaaaacag atgaagcccc ctacaccgaa cagcaatccg gtacgttctc
     2521 ggtcgaatcc gcaggcatta cccttcagac acataccgac agcagcggcg gacacctcgt
     2581 cgtcgtacgg gtttccgacg cggcagaacg cgcaggcttg aggcgcggcg acgaaattct
     2641 tgccgtcggg caagtccccg tcaatgacga agccggtttc cgcaaagcta tggacaaggc
     2701 aggcaaaaac gtccccctgc tgatcatgcg ccgtggcaac acgctgttta tcgcattaaa
     2761 cctgcaataa cccacataat ttaaccaaaa tattttttaa atgataaaat gcccgtcaat
     2821 accgattaac gggcatttta aaaaatcagt taattgattt caaataagta ttttccggaa
     2881 cagaaaatac tttcgcccat tttgccaaca aaatccgaac cgttgcggac agaaaccgcc
     2941 ccatccggac gcttaacacc cccgtaaacc atgcagctga tcgactattc acattcattt
     3001 ttctcggttg tgccaccctt tttggcactg gcacttgccg tcattacccg ccgcgtactg
     3061 ctgtctttag gcatcggtat tctggtcggc gttgcctttt tggtcggcgg caaccccgtc
     3121 gacggtctga cacacctgaa agacatggtc gtcggcttgg cttggtcaga cggcgattgg
     3181 tcgctgggca aaccaaaaat cttggttttc ctgatacttt tgggtatttt tacttccctg
     3241 ctgacctact ccggcagcaa tcaggcgttt gccgactggg caaaacggca cattaaaaac
     3301 cggcgcggcg cgaaaatgct gaccgcctgc ctcgtgttcg taacctttat cgacgactat
     3361 ttccacagtc tcgccgtcgg tgcgattgcc cgccccgtta ccgacaagtt taaagtttcc
     3421 cgcaccaaac tcgcctacat cctcgactcc actgccgcgc ctatgtgcgt gctgatgccc
     3481 gtttcaagct ggggcgcgtc gattatcgcc acgcttgccg gactgctcgt tacctacaaa
     3541 atcaccgaat acacgccgat ggggacgttt gtcgccatga gcctgatgaa ctattacgca
     3601 ctgtttgccc tgattatggt gttcgtcgtc gcatggtttt ccttcgacat cggctcgatg
     3661 gcacgtttcg aacaagccgc gttgaacgaa gcccacgatg aaactgccgt ttcagacgct
     3721 accaaaggtc gtgtttacgc actgattatt cccgttttgg ccttaatcgc ctcaacggtt
     3781 tccgccatga tctacaccgg cgcgcaggca agcgaaacct tcagcatttt gggggcattt
     3841 gaaaacacgg acgtaaacac ttcgctggta ttcggcggca cttgcggcgt ccttgccgtc
     3901 gttctctgca cgctcggcac gattaaaacc gccgactatc ccaaagccgt ttggcagggt
     3961 gcgaaatcta tgttcggcgc aatcgccatt ttaatcctcg cttggctcat cagtacggtt
     4021 gtcggcgaaa tgcacaccgg cgattacctc tccacactgg ttgcgggcaa catccatccc
     4081 ggcttcctgc ccgtcatcct cttcctgctc gccagcgtga tggcgtttgc cacaggcaca
     4141 agctggggga cgttcggcat tatgctgccg attgccgccg ccatggcggt caaagtcgat
     4201 ccctcactga ttatcccgtg tatgtccgcc gtgatggcgg gggcggtatg cggcgaccac
     4261 tgttcgccca tctccgacac gaccatcctg tcgtccacag gcgcgcgctg caaccacatc
     4321 gaccacgtta cctcgcaact gccttacgcc ttaaccgttg ccgccgccgc cgcatcgggc
     4381 tacctcgcat tgggtctgac aaaatccgcg ctgttgggct ttggcacgac aggcattgta
     4441 ttggcggtgc tgatttttct gttgaaagat aaaaaacgcg ccaacgcctg acccctttcc
     4501 ctgttcagac ggcatatgcc gtctgaagct ttttggagca aaccgcaatg accgtccccc
     4561 atattccgcg cggccccgtc atggcagaca ttgccgcctt ccgcctgacc gaagaggaaa
     4621 agcaacgcct gctcgatccc gccgtaggcg gcatcatcct cttccgccgc aacttccaaa
     4681 acatcgaaca actcaaaaca ctcaccgccg aaatcaaagc cctgcgcaca cccgaactca
     4741 ttatcgccgt cgatcacgaa ggcggcaggg tgcaacgttt catcgaaggc ttcacccgcc
     4801 tgcccgcaat gagtacgctc ggcgagattt gggacaaaga cggcgcgtcc gccgccgaaa
     4861 ccgccgccgg acaagtcggc cgggttttgg caaccgagct ttccgcctgc ggcatcgatt
     4921 tgtccttcac gcccgtctta gatttggact ggggaaactg ccccgtcatc ggcaaccgca
     4981 gtttccacca caatcccgaa gcggtcgccc acctcgccct cgcccttcaa aaaggtttgg
     5041 caaaaggcgg tatgaaatcc tgcggcaaac attttcccgg acacggattt gtcgaaggag
     5101 acagccatct ggtcttgccg gaagacaggc gcagcctgtc cgaactcgaa gccgccgacc
     5161 tcgccccctt ccacattatg agccgcgaag gtatggcggc ggttatgccc gcccacgtcg
     5221 tttatccaca agtggacaca aagcccgcag ggttttccga aatctggctc aaacaaattt
     5281 tgcgccgcga tatcggattc aaaggcgtga ttttctcgga cgatttgact atggagggcg
     5341 cgtgcggtgt cggcggcctc aaagaacgcg cccgcatttc ctttgaggca ggttgcgaca
     5401 tcgtcctcgt ctgcaaccgt cccgaccttg tggacgaact gcgcgaagat ttccgcattc
     5461 ctgacaatcc cgctttggcg caacgttggc aatatatggc caacacgctc ggcagtgccg
     5521 ccgcgcaagc cgttatgcag acggcggatt tccaagaggc gcaagccttt gttgccggcc
     5581 ttgcctcgcc gcaggataca gcgggcggcg taaaagtcgg cgaagccttt taaaccggct
     5641 gcgtttcaac aatctgccga tttcatcaac cgtttgtcag ggaaaggcaa tgattttttc
     5701 ggtcaggtag aaagttatct tattgaatta cttaaagata atgatgatta tcaacactgt
     5761 attcaaacac actcctttaa atccgcccga cacgcggcaa aaaggcaaaa cggtataggc
     5821 acgccgtatt ttttgcgcta taatcacgcc ttacttaatt cggaatgtag cgcagcccgg
     5881 tagcgcactt cgttcgggac gaaggggtcg gaggttcgaa tcctctcatt ccgaccatat
     5941 tcaaaccgcc tcggcatgga ttgccggggc ggtttttccc ttttggcgtc
//
LOCUS       DAXIDM010000109         5964 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000109 DAXIDM010000000
VERSION     DAXIDM010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5964
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.109"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            54..1592
                     /gene="murJ"
                     /locus_tag="ACFOAE_001742"
     CDS             54..1592
                     /gene="murJ"
                     /locus_tag="ACFOAE_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HFC6885184.1"
                     /translation="MNMLGALAKVGSLTMVSRVLGFVRDTVIARAFGAGMATDAFFVA
                     FKLPNLLRRVFAEGAFAQAFVPILAEYKETRSKEATEAFIRHVAGMLSFVLVIVTALG
                     ILAAPWVIYVSAPGFAKDADKFQLSIDLLRITFPYILLISLSSFVGSVLNSYHKFSIP
                     AFTPTFLNVSFIVFALFFVPYFDPPVTALAWAVFVGGILQLGFQLPWLAKLGFLKLPK
                     LNFKDAAVNRVMKQMAPAILGVSVAQISLVINTIFASYLQSGSVSWMYYADRMMELPG
                     GVLGAALGTILLPTLSKHSANQDTEQFSALLDWGLRLCMLLTLPAAVGLAVLSFPLVA
                     TLFMYREFTLFDAQMTQHALIAYSFGLIGLIMIKVLAPGFYARQNIKTPVKIAIFTLI
                     CTQLMNLAFIGPLKHVGLSLAIGLGACINAGLLFYLLRRHGIYQPGKGWAAFLAKMLL
                     SLAVMGGGLYAAQIWLPFDWAHAGGMQKAARLFILIAVGGGLYFASLAALGFRPRHFK
                     RVES"
     gene            1725..2681
                     /locus_tag="ACFOAE_001743"
     CDS             1725..2681
                     /locus_tag="ACFOAE_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003750210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheT family hydrolase"
                     /protein_id="HFC6885185.1"
                     /translation="MILTPPDTPFFLRNGNADTIAAKFLQRPAPTYRRELLPDSTGKT
                     KVAYDFSDGISPDAPLVVLFHGLEGSSRSHYAVELMLAVRSRGWHGAVVHFRSCGGIA
                     NTAPVFYHLGDTAEIAFTLDTLAARYREIYAVGVSLGGNALAKYLGERGENALPQAAA
                     AVSAPVDAEAAGRRFDSGITRLLYTRYFLRTLIPKARSLHGFQTAFAAGCKTLGEFDD
                     RFTAPLHGFADRHDYYRQTSCKPLLKHVAKPLLLLNAVNDPFLPPEALPRADEVSEAV
                     TLFQPTHGGHVGFVGSTGGRLHLQWLPQTVLSYFDSFRTNRR"
     gene            2732..3514
                     /gene="trpC"
                     /locus_tag="ACFOAE_001744"
     CDS             2732..3514
                     /gene="trpC"
                     /locus_tag="ACFOAE_001744"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HFC6885186.1"
                     /translation="MTDILNKILTAKAQEVAAQKAAVNAEHIRALAAEAAPVRSFIDS
                     IRGKHRLNLPAVIAEIKKASPSKGLIRPDFRPAEIARAYENAGAACLSVLTDEPYFQG
                     SPEYLKQAREAVSLPVLRKDFIIDEYQVYQARAWGADAVLLIAAALEREQLERFEAVA
                     HELGMTVLLELHDESELEKCRNLTTPLWGVNNRNLRTFEVSLDQTLSLLPALEGKTVV
                     TESGITGKADVEFMRTRGVHTFLIGETFMRADDIEAEVGKLF"
     gene            3579..5879
                     /gene="recQ"
                     /locus_tag="ACFOAE_001745"
     CDS             3579..5879
                     /gene="recQ"
                     /locus_tag="ACFOAE_001745"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFC6885187.1"
                     /translation="MHRPTAKQILHEVFGYPEFRGRQEAVINTLAGGGSLTVLMPTGG
                     GKSLCYQIPALMCEGVAVVVSPLIALMNDQVANLHAAGIEAAAVNSGTSADGAREIAD
                     KLAQGRLKLLYVAPERLVTDRFLRFLDQQTVSLFAIDEAHCVSQWGHDFRPEYQQLGM
                     LAERYPNVPRIALTATADAATRADIKHYLHLDNAPEFISSFDRPNIYYQVIEKNNGKK
                     QLLDFIRKQMHGQSGIVYCLSRKKVEDVAQFLCENGLEAIPYHAGLSMDVREENQRRF
                     THEDNIIVVATVAFGMGIDKPDVRFVAHLDMPQSVEHFYQESGRAGRDGLPAASWLCY
                     GLNDWVLLRERIAEGNSDEVQKQIEMQKLDAMLSVCETAACRRVLLLKHFGEESEPCG
                     HCDNCLHPPVRFDGTVLVQKLLSCVYRAGQRFAAGYITNLLRGKSDDWIRGNRHEQLS
                     TFGIGTELSDKEWRSVIRQCISLGYLTVNITRYQALQLTEAAKKVLKGETEVMLRPLK
                     RDKPAARTLKDNWLRTEREERLWQALRVWRMKQAEAEVIPAYMIFGDKTLRDLVEKMP
                     QDLNGLHDIYGLGEAKIDRFGHGILEVCRNTADFSHNAVIRPQTEREQQLRQKLEAWR
                     YEQARAENCALHAVLSDESLADMLAATPETETDLEGVHGLGSVRAAKYGRDILAVCRP
                     FSDGIDEAAKHKRRLMRALIQWCNETAKHEQSEPYRILSKAALRAIAAKQPEGLAELA
                     AVYGVGEEKAARYGAAVLTVLGQNAV"
BASE COUNT         1291 a         1791 c         1616 g         1266 t
ORIGIN      
        1 gtcgtacaat acgcgccgtt gccccaaacg ggtacgactg ttgaggaaca atgatgaata
       61 tgctgggagc tttggcaaaa gtcggcagcc tgacgatggt gtcgcgcgtt ttgggatttg
      121 tgcgcgatac ggtcattgcg cgcgcattcg gcgcgggcat ggcgacggat gcgttttttg
      181 tcgcgttcaa actgcccaac ctgcttcgcc gcgtgtttgc ggagggggcg tttgcccaag
      241 cgtttgtgcc gattttggcg gaatataagg aaacgcgttc gaaagaggcg acggaggctt
      301 ttatccgcca tgtggcgggg atgctgtcgt ttgtgctggt catcgttacc gcgctgggca
      361 tacttgccgc gccttgggtg atttatgttt ccgcacccgg ttttgccaaa gatgccgaca
      421 aatttcagct ctccatcgat ttgctgcgga ttacgttccc ctatatctta ttgatttcac
      481 tttcctcttt tgtcggctcg gtactcaatt cctatcataa attcagcatt ccggcgttta
      541 cgcccacgtt cctgaacgtg tcgtttatcg tattcgcgct gtttttcgtg ccgtatttcg
      601 atcctcccgt taccgcgctg gcttgggcgg tttttgtcgg cggcatttta caactcggct
      661 tccaactgcc ctggctggcg aaactgggtt ttttgaaact gcccaaactg aatttcaaag
      721 atgcggcggt caaccgcgtc atgaaacaga tggcgcctgc gattttgggc gtgagcgtgg
      781 cgcagatttc tttggtgatc aacacgattt tcgcgtctta tctgcaatcg ggcagcgttt
      841 catggatgta ttacgccgac cgcatgatgg agctgcccgg cggcgtgctg ggggcggcac
      901 tcggtacgat tttgctgccg actttgtcca aacactcggc aaaccaagat acggaacagt
      961 tttccgccct gctcgactgg ggtttgcgcc tgtgcatgct gctgacgctg ccggcggcgg
     1021 tcggactggc ggtgttgtcg ttcccgctgg tggcgacgct gtttatgtac cgcgaattta
     1081 cgctgtttga cgcgcagatg acgcaacacg cgctgattgc ctattctttc ggtttaatcg
     1141 gcttaatcat gattaaagtg ttggcacccg gcttctatgc gcggcaaaac atcaaaacgc
     1201 ccgtcaaaat cgccatcttc acgctcatct gcacgcagtt gatgaacctt gcctttatcg
     1261 gcccactgaa acacgtcgga ctttcgcttg ccatcggtct gggcgcgtgt atcaatgccg
     1321 gattgttgtt ttacctgttg cgcagacacg gtatttacca acctggcaag ggttgggcgg
     1381 cgttcttagc aaaaatgctg ctctcgctcg ccgtgatggg aggcggcctg tatgccgccc
     1441 aaatctggct gccgttcgac tgggcacacg ccggtggaat gcaaaaggcc gcccggctct
     1501 tcatcctgat tgccgtcggc ggcggactgt atttcgcatc actggcggct ttgggcttcc
     1561 gtccgcgcca tttcaaacgg gtggaaagct gaccgatgcc gatatccttt ttcggcaaac
     1621 gctttttccg cgcctatatt cgggcgcgca tcccccgcgt ccgcaccggc cggacgggct
     1681 gccgcatcat caatgccgtc tgaaaacaga aaaaccgata ccttatgatt ttaacaccgc
     1741 cggacacgcc ctttttcctc cgcaacggca atgccgacac gattgccgcc aaattcctgc
     1801 aacgccccgc acccacatac cgccgcgagc tgcttcccga cagcacgggt aaaaccaaag
     1861 tcgcctacga tttttcagac ggcatttcgc ccgatgcgcc gctggtcgtg ctgtttcacg
     1921 gtttggaagg aagcagccgc agccattacg cggtcgaact gatgctcgcg gtacgcagcc
     1981 gcggttggca cggcgcagtc gtccatttcc gcagctgcgg cggcattgcc aacaccgctc
     2041 cggtgttcta ccacttgggc gataccgccg aaatcgcctt tactttggac acgcttgccg
     2101 cgcgttaccg tgaaatatac gccgtcggcg tatcgctggg cggcaacgcg ctggcaaaat
     2161 atttgggcga acggggcgaa aacgcgctgc cgcaagccgc tgccgccgta tccgcccccg
     2221 tcgatgcaga ggcggcaggc agacgcttcg acagcggcat cacgcggctg ctctacacgc
     2281 gctacttcct ccgcaccctg atacccaaag cacggtcgct ccacggtttt cagacggcat
     2341 ttgccgcagg gtgcaaaaca ctgggcgagt ttgacgaccg tttcaccgca ccgctgcacg
     2401 gctttgccga tcggcacgac tactaccgcc aaacttcctg caaaccgctg ctcaaacacg
     2461 ttgccaaacc gctgctcttg ctcaatgccg tcaacgaccc cttcctgccg cccgaagcgc
     2521 tgccccgcgc agacgaagtg tccgaagccg ttaccctgtt ccagccgaca cacggtggtc
     2581 atgtcggctt tgtcggcagc accggcggca ggctgcacct gcaatggttg ccgcagaccg
     2641 tcctgtccta tttcgacagc ttccgcacaa acaggcgtta acggtttgat gctaatattc
     2701 cccctttccc cagacgaata cggaacacga catgaccgac atcctcaata aaatccttac
     2761 cgccaaggca caggaagttg ccgcccaaaa agccgccgtc aacgccgaac acatccgcgc
     2821 acttgccgca gaagccgcgc ccgtccgcag cttcatcgat tcgatacgcg gcaaacaccg
     2881 cctaaacctg cccgccgtca ttgccgaaat caaaaaggca agcccgagca aaggcctgat
     2941 ccgtccggac ttccgacctg ccgagattgc ccgcgcctat gaaaacgccg gggcggcgtg
     3001 tttgtccgta ctgaccgacg aaccctattt ccaaggttcg cccgaatacc tcaaacaggc
     3061 gcgcgaagcc gtatctctgc ccgttttgcg taaagacttc atcatcgacg aataccaggt
     3121 ttatcaggcg cgcgcctggg gggcggatgc cgtcctgctg attgccgccg cactggaacg
     3181 ggaacaattg gaacgctttg aagcggtggc gcacgaattg ggcatgaccg tcctgctcga
     3241 gctgcacgat gaaagcgaat tggaaaaatg ccgcaacctg accacgccgt tgtggggtgt
     3301 aaacaaccgc aacctgagga cttttgaagt ctccctcgac caaaccctgt cgctgctgcc
     3361 cgcactggaa ggcaaaaccg tcgttaccga aagcggcatt acaggtaagg cggatgtgga
     3421 atttatgcgg acgcgcggtg tgcacacctt cctgatcggc gaaacgttca tgcgtgccga
     3481 cgatattgaa gcagaagtgg gcaaactctt ctaaatcccg atttcagacg gcatattgcc
     3541 gccaaccgac caacaccctt accgagcacg gaaccatcat gcaccgaccg accgccaaac
     3601 agattctgca cgaagtattt ggttatcccg aatttcgcgg caggcaggag gctgtcatca
     3661 atactttggc aggcggcggg agtttgacgg tgctgatgcc gacgggcggc ggcaagtctt
     3721 tgtgttacca gattcccgcg ctgatgtgcg aaggcgtggc ggttgtcgta tcgccgctga
     3781 ttgcgttgat gaacgaccaa gtggcaaacc tgcacgccgc cggcatcgaa gcggcggcag
     3841 tcaacagcgg cacatcggca gatggggcgc gcgagattgc cgacaagctt gcccaaggtc
     3901 gtctgaaact gctttatgtc gcaccggaac gcctagttac cgaccgcttt ttgcgttttc
     3961 tcgaccaaca aaccgtcagc ctgttcgcca ttgacgaggc gcactgcgtc agccaatggg
     4021 gacacgattt ccgccccgaa taccaacagc tcggcatgct tgccgaacgc tatccgaacg
     4081 tcccgcgcat cgccctgacc gctaccgccg atgccgccac gcgcgccgac atcaagcatt
     4141 atctgcactt ggacaatgcg cccgaattta tttccagctt tgaccgcccg aatatttatt
     4201 atcaggttat cgaaaaaaat aatggtaaaa aacaattgct ggatttcatc cgcaagcaga
     4261 tgcatgggca aagcggcatt gtgtattgcc taagccgcaa aaaagtcgag gatgtggcgc
     4321 agtttttgtg tgaaaatggc ttggaggcga ttccgtatca tgccggtttg agcatggacg
     4381 tgcgcgagga aaaccaacgc cgctttacgc atgaagacaa tattatcgtg gtggcgaccg
     4441 tggcgttcgg catgggcata gacaaacccg acgtgcgctt tgtcgcccat ctcgatatgc
     4501 cccagagtgt cgaacatttc tatcaggaat cggggcgtgc cggccgggac gggctgcctg
     4561 ccgcgagctg gctgtgttac ggtttgaacg attgggtgtt gctgcgcgaa cggattgccg
     4621 aaggcaacag cgacgaggtg caaaagcaaa tcgaaatgca aaaactcgat gccatgcttt
     4681 ccgtctgcga aaccgccgcc tgccgccgcg tactgctgct caaacatttc ggcgaagaat
     4741 ccgaaccctg cggccattgc gacaactgcc tgcatccgcc cgtacggttt gacggcacgg
     4801 tgttggtgca aaaattactc agctgcgtgt accgcgccgg acaacgtttt gccgccggtt
     4861 acatcaccaa ccttttgcgc ggcaaaagcg acgattggat acgcggcaac cggcacgaac
     4921 aactgtccac cttcggcatc ggtacggagt tgtccgacaa agaatggcgc agcgtcatcc
     4981 gccagtgtat cagcctcggc tacctcaccg tcaacattac ccgatatcag gcattgcaac
     5041 tgaccgaagc cgccaaaaaa gtcctcaaag gcgaaaccga agtgatgctg cgtccgctca
     5101 agcgcgacaa gcccgccgcc cgcaccctca aagacaactg gctgcgtacc gaacgcgaag
     5161 aacgcctgtg gcaggcattg cgcgtttggc gtatgaaaca ggcagaagcc gaagtcatcc
     5221 ccgcctatat gattttcggc gacaaaaccc tgcgcgacct tgtcgaaaaa atgccgcaag
     5281 acctcaacgg actgcacgac atctacggtt tgggcgaagc caaaatcgac cgtttcggac
     5341 acggcatcct cgaagtctgc cgcaacaccg ccgactttag ccacaatgcc gtcatccgcc
     5401 cgcaaaccga acgcgaacag caactgcgtc aaaaactcga agcctggcgg tatgaacagg
     5461 caagggcgga aaactgcgcc ctgcatgccg tcctctccga cgaaagcctt gccgatatgc
     5521 ttgccgccac gcctgaaacc gaaaccgacc tcgaaggcgt acacggcttg ggcagcgtac
     5581 gcgccgccaa atacggacgg gacatcctcg ccgtctgccg tccgttttca gacggcatcg
     5641 atgaagccgc caaacacaaa cgccgcctga tgcgcgccct gattcaatgg tgcaacgaaa
     5701 cggcaaaaca cgaacagtcc gaaccctacc gcattctcag caaagccgcc ctgcgcgcca
     5761 ttgccgccaa acagccggaa ggcttggcgg agcttgccgc cgtatacggc gtaggcgaag
     5821 aaaaagccgc acgttacggt gcggcggtgt tgacggtgtt gggacaaaat gccgtctgaa
     5881 gcccgttacc aagtttcaga cggcattgcc tctatttaaa aattcctgtt tttatagtgg
     5941 attaacaaaa atcaggacaa ggcg
//
LOCUS       DAXIDM010000110         5888 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000110 DAXIDM010000000
VERSION     DAXIDM010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5888
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.110"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            132..566
                     /locus_tag="ACFOAE_001746"
     CDS             132..566
                     /locus_tag="ACFOAE_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HFC6885188.1"
                     /translation="MPLPAPCRFAKPAASFLSMALLSCQLSHAATAYIPLNDFQPNCD
                     IRRLGLTQGQHNELRKIRAAFKMAGDRARLKVMHSEHSRRRSVVEIISSDVFNRNEAR
                     DYVESRYLSGMDFAVDELEIQHRFFHILTPQQQQMWLSSCLK"
     gene            complement(579..1442)
                     /locus_tag="ACFOAE_001747"
     CDS             complement(579..1442)
                     /locus_tag="ACFOAE_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFC6885189.1"
                     /translation="MELNEFFDKAYAVLRRLDAVLPPEPGHTDWNALAFRWQSAGKKG
                     FLEHLPDPHTFPLVRLAGVGRQTELLVRNTEQFIVGRPANNVLMSGARGTGKSSLVKA
                     LLHEYADKGLRLIEVDKSDLIGLPYLLTLLKERPEKFIVFCDDLSFESGDETYKALKT
                     ALDGGLSQRCANVLVYATSNRRHLMPEYFDENAGTTGMRGEIHQKEAVEEKISLSDRF
                     GLWLSFYPFDQNDYLAAVQNWLEDFGVPYDETAQMAALQWAQTRGSRSGRSAWQFACD
                     WAGRLPKQRAL"
     gene            complement(1450..2067)
                     /locus_tag="ACFOAE_001748"
     CDS             complement(1450..2067)
                     /locus_tag="ACFOAE_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HFC6885190.1"
                     /translation="MFTGIVQGLGKLTAIHRPSEAFHTYVVELPQEAADNLQRGASVA
                     NNGCCLTITEIEGNRVSFDLMAETLAKTNLGLLKEGDCVNIERAARFGDEIGGHVMSG
                     HIMATVPIVEIERDGFNRTVWFSLPHELKPYILTKGFVGLDGCSLTIGKVEDGRFNVH
                     LIPETLERTLFGSRKVGDRINIEIDPNTQAIVDTVERLMAQRYAK"
     gene            complement(2230..2844)
                     /locus_tag="ACFOAE_001749"
     CDS             complement(2230..2844)
                     /locus_tag="ACFOAE_001749"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0061603 - molybdenum cofactor
                     guanylyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HFC6885191.1"
                     /translation="MKTSNFSKRTSAMKTFALILADGQASRMGGEDKGLALLGGKALI
                     DHVIDRVRPQVSHIAISTNRNLEEYARRSPHIFPDARQWQHFGPLSALCTAANDLQLA
                     TADWLLVVPCDMPYLPDDLVARFETVSKRTPLCNAYYVETPITMHYNIMYIRPQILQS
                     AIPYLFSGMKTLRSWLQQQRARSVRFEFDGHFADLNTQIDLQEG"
     gene            3050..4822
                     /locus_tag="ACFOAE_001750"
     CDS             3050..4822
                     /locus_tag="ACFOAE_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite sensor histidine kinase"
                     /protein_id="HFC6885192.1"
                     /translation="MILPARFSDGISLSLRLKLLTGVWVGLAALSVVLTLLLSLRLEN
                     AASVIEEAGNLRMQAYRLAYMAGEGSPRSQIDNQVDEFEKSLNRISQSDAIHPLIPSD
                     TPLAYDLIQSMLIIDWQAHILPPLQSYRRPTQVDLYRFAGNIELFLQALENANEKNTW
                     WLRRFQWAIMLMTLVSSVLMLFWHQIWVIRPLQALREGAERIGRRCFDIPVPEGGTPE
                     FKQVGRCFNQMGGRLKILYDDLEGQVAEQTRSLEKQNQNLTLLYQTTRDLHQSYIPQQ
                     AAEHFLNRILPAVGADSGRVCLDGGSDVYVSIHHADCGTAASDLGKYHEEIFPIEYQN
                     ETLGRLLLSFPNGISLDEDDRILLQTLGRQLGVSLAGAKQEEEKRLLAVLQERNLIAQ
                     GLHDSIAQALTFLNLQVQMLETAFAENKREEAVENIGFIKTGVQECYEDVRELLLNFR
                     TKISNKEFPEAVADLFARFTQQTGITVETAWENGSFLPPQEAQLQMIFILQESLSNIR
                     KHARATHVKFTLSEHGGRFTMTIQDNGQGFDTEKIGEPTGSHVGLHIMQERAKRIHAV
                     LEIRSQAQQGTTVSLTVASEESLK"
     gene            4819..5475
                     /locus_tag="ACFOAE_001751"
     CDS             4819..5475
                     /locus_tag="ACFOAE_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFC6885193.1"
                     /translation="MTIKIILIDDHTLFRSGIKSLLSRQHDFEVIGEAADGLSGIKMI
                     NRLQPDVVLLDLDMPGMNGREALSQIISINPQQAVIMLTVSEDNDDLTECMRIGARGY
                     LLKNINADFLLESIRKAAEGDNVFSPEMTAKLVKSLISPQPAQGTQALSSLTPRELEI
                     LGYLAAGHSNKIIARHLDLAESTVKVHVQHLLRKLNLSSRVQAAVYAIRHNVPQPVLE
                     "
BASE COUNT         1451 a         1658 c         1358 g         1421 t
ORIGIN      
        1 gttccgattc cgccgttatg tctgcctgcc ggacatacgt acgcattatt aacaaaagtt
       61 aaccgcgata ataccatctt tcacacgtca atctagtata tttcctaaaa tttccaacaa
      121 gaggaaaagc cgtgccactg cctgctccct gccgttttgc caaacctgcc gcctcttttt
      181 taagtatggc tttgctttcc tgccagcttt cccacgccgc cacggcttat atccccctga
      241 acgattttca accgaactgc gacatacgcc ggctcggact gacacagggt cagcacaatg
      301 aactgcgtaa aatccgcgcc gccttcaaaa tggcgggcga cagggcgcgt ttgaaggtta
      361 tgcattccga acacagccgc cgccggtctg tcgtcgaaat catttcttcg gatgttttta
      421 atcggaacga ggcgcgcgat tatgtcgaaa gccgctattt gtccggtatg gattttgcgg
      481 tggacgaatt ggaaatccaa caccgcttct tccatatcct cacaccgcaa cagcagcaaa
      541 tgtggctttc ttcctgcctc aaataatccc cgaaacgctc acaacgcccg ttgtttcggc
      601 agcctgcccg cccagtcgca ggcaaactgc cacgcggaac gtcccgaacg gctgccccgc
      661 gtctgcgccc actgcaatgc cgccatctgt gcggtttcat catacggcac gccgaaatct
      721 tccagccaat tttgcaccgc cgccagataa tcgttttgat cgaacggata aaaactgagc
      781 cacaatccga atcggtcgga cagggatatt ttttcttcca ccgcttcttt ctgatggatt
      841 tccccccgca tccccgtcgt accggcattc tcgtcaaaat attcgggcat caggtgccgt
      901 ctgttggaag tcgcgtaaac caaaacgttg gcgcaacgtt gagacagacc gccgtctaac
      961 gcggttttca atgccttata ggtttcatcg ccgctttcaa acgacaaatc gtcgcaaaat
     1021 acgataaatt tttccggacg ttccttcaaa agcgtcaaca ggtaaggcag gccgattaaa
     1081 tcgcttttat cgacttcgat caggcgcaat cccttatccg catattcgtg tagcagggct
     1141 ttgaccagcg aggatttgcc tgttccgcgc gcgccgctca tcaatacatt gttcgcgggt
     1201 ctgccgacaa tgaactgttc ggtattacgc accagcaatt cggtttgcct gccgactccc
     1261 gccagcctta ccaagggaaa ggtgtgcgga tcgggcaagt gttccaaaaa accttttttg
     1321 cccgcactct gccagcggaa ggcaagcgcg ttccaatccg tatgcccggg ttcgggcgga
     1381 agcacggcat ccaaacgccg caaaacggca taggctttat cgaaaaattc gttcaattcc
     1441 atctctacct cactttgcat atctttgcgc catcagccgt tcgacggtgt cgacgattgc
     1501 ctgcgtattc ggatcgattt cgatgttgat cctgtcgccg acctttctgc tgccgaacag
     1561 cgtccgttcc aaagtttcgg gaatcagatg gacattgaaa cggccgtctt cgactttgcc
     1621 tatggtcagg ctgcaaccgt ccaagccgac gaaccctttg gtcaggatat agggtttgag
     1681 ttcatgcggg agcgaaaacc aaaccgtgcg gttgaacccg tcccgttcga tttcgacaat
     1741 aggcacggtt gccataatgt gtccgctcat gacgtgtccg ccgatttcgt ctccgaaacg
     1801 cgccgcccgt tcgatgttga cgcaatcgcc ttccttcagc agccccaaat tggtttttgc
     1861 caaagtttcc gccattaaat cgaaactgac gcggtttcct tcgatttcgg taatcgtcag
     1921 gcagcagccg ttattggcga ccgatgcgcc gcgttgcaga ttgtccgccg cctcttgcgg
     1981 aagctcgacg acataagtgt gaaatgcctc cgacgggcgg tggattgccg tcagttttcc
     2041 caatccttga acaatgcctg taaacataat cctgtttccc tgtgtcggta aaaatggtgc
     2101 aaattgtagc atctccccgc gaaaaatgcc gtctgaaatg ccttcagaca gcattatgcc
     2161 tccgattcgg gcaaaaaccg cccggtatgg cttgaccttt cctttccacg ccggtcggcg
     2221 gtcttgccct tatccctcct gcaaatcgat ttgcgtgttc aagtcggcaa aatgcccgtc
     2281 aaactcgaat ctgaccgacc gcgccctttg ctgctgcaac cagcttctta atgttttcat
     2341 acccgaaaac agatagggaa tcgcgctttg cagaatctgc gggcggatat acataatgtt
     2401 gtagtgcatc gttatcggcg tttccacata atacgcattg cacaacggtg tgcgtttcga
     2461 cacggtttca aacctcgcca ccaaatcgtc cggcagatac ggcatatcgc acggcacaac
     2521 caaaagccag tcagcagtcg ccaactgcaa atcgttggct gcggtacaca atgccgaaag
     2581 cgggccgaaa tgctgccact gccgcgcatc gggaaaaata tgcggacttc ttcgagcata
     2641 ttcttccaaa ttccggttgg tgctgatggc gatatggctg acctgcggcc tgaccctgtc
     2701 gatgacatgg tctatcagtg ccttaccccc caaaagagca agccccttgt cctcgcctcc
     2761 catacggctc gcctgaccgt cggccagtat cagggcaaaa gttttcattg cggatgttct
     2821 cttggaaaag ttcgaggttt tcatgattgc agtctgccgt tcccaatgac tcaaaatgcc
     2881 gtctgaagca gatggcaaat aaattcatat tatctgaatt ttatcataac atgatttaac
     2941 actgaagcgg tgcggattaa gttttcctta accaattctt tctgagcagt tgtatctaat
     3001 cccaaagaat gatattgttt gcattattta gaacaatttt tcgccgagca tgatactgcc
     3061 agcccgtttt tcagacggca tcagcctttc cctacgcctg aaactcctga ccggagtgtg
     3121 ggtcgggttg gcggcattgt ctgtcgtttt gacactgctg ctctctttgc gtctggaaaa
     3181 cgcggcctcc gtcatcgaag aggcgggcaa cttgagaatg caggcatacc gtctggcata
     3241 catggcgggt gaaggatctc cccgctccca aatagacaat caggttgacg aatttgaaaa
     3301 aagcctgaat cgtatttcac aaagtgatgc catccatccg ctgattcctt cggacacccc
     3361 tcttgcttat gatttgatac aatccatgct gattatagat tggcaggcac acatcctccc
     3421 cccgctccag tcctaccggc gaccgactca ggtcgatctc taccgctttg ccggaaacat
     3481 cgaactgttt ttgcaggcat tggaaaatgc caacgaaaaa aacacatggt ggctcaggcg
     3541 ttttcaatgg gcaattatgt tgatgacgct ggtgtcgtct gtactgatgc tgttttggca
     3601 ccagatttgg gttatccggc cgctgcaggc gttaagggaa ggtgcggaac gcatcggacg
     3661 gaggtgtttc gatattccgg ttcccgaagg cggtacgccg gaattcaaac aggtcgggcg
     3721 ttgtttcaat caaatgggcg gcaggttgaa aattttatat gatgatttgg aaggacaagt
     3781 cgccgagcag acacgcagtc tcgaaaaaca aaatcaaaac ctgaccctgc tgtaccaaac
     3841 tacacgggac ctgcaccaat cctacatacc gcaacaggct gcagaacatt ttctaaaccg
     3901 tatcctgccc gccgtaggag cagattccgg cagagtttgt ttggacggcg gatccgatgt
     3961 ttatgtttcc attcatcatg cggattgcgg cacagcagct tcggatttgg ggaagtacca
     4021 tgaggaaatc ttccccattg agtaccagaa cgaaacattg ggcaggctgt tgctcagctt
     4081 tccaaacggc atttctcttg atgaagacga ccgcatcctg cttcaaacac taggcaggca
     4141 attgggcgta tcgcttgccg gcgcaaaaca ggaggaagaa aaacgcctgc ttgcagtatt
     4201 gcaggaacgc aacctgattg cgcaaggatt acatgacagc atcgcacaag cattaacgtt
     4261 cctaaaccta caggtacaga tgctggaaac cgcctttgcc gaaaacaaac gggaggaagc
     4321 cgtagaaaac atcggcttca tcaaaacagg cgtgcaggaa tgttatgaag atgtccgcga
     4381 actgctgctc aacttccgta ccaaaatcag caataaagaa tttcccgaag ccgttgccga
     4441 cctattcgcc cgctttacgc aacaaaccgg gataacggtc gaaaccgcct gggaaaacgg
     4501 ttcgttcctg ccgcctcagg aagcgcagct ccaaatgatt tttatcctgc aggaaagcct
     4561 gtccaacatc cgcaaacacg cccgcgccac ccatgtaaaa ttcacccttt ccgaacacgg
     4621 cggacgcttt accatgacca tccaagacaa cggacaaggt ttcgacacgg agaaaatagg
     4681 agaacccacg ggcagccatg tcggactgca catcatgcag gagcgtgcca aacgcatcca
     4741 tgccgtttta gaaatccgtt cccaagctca acagggaacc accgtctcat tgacggttgc
     4801 atctgaagaa agcttgaaat gaccattaaa attatcctga tagacgacca taccctcttc
     4861 cgcagcggca ttaaatccct tttgtcgcgc caacatgatt ttgaggtcat cggcgaagcc
     4921 gcagacggcc tctcgggcat taaaatgatc aaccggctcc aacccgatgt cgtcctgctt
     4981 gaccttgata tgcccggtat gaacggacgc gaagcactct cccaaatcat cagcatcaat
     5041 ccgcagcagg cagtgattat gctgaccgtt tccgaagaca acgacgactt gaccgaatgt
     5101 atgcgcatcg gcgcgcgcgg ctacctgctg aaaaacatca acgccgactt tctgctcgaa
     5161 agcatacgca aagccgccga aggcgataat gtattctcgc ccgagatgac cgccaaactc
     5221 gtcaaaagcc tgatttcccc ccaacctgcc caagggacgc aggcactctc ctcacttacc
     5281 cctcgtgaac tggaaatctt gggctatctc gccgcaggac acagcaacaa aatcatcgcc
     5341 cgccacctcg atcttgccga atccaccgtc aaagtccacg ttcaacacct gctccgcaaa
     5401 ctcaacctca gcagccgggt gcaggccgct gtttacgcca tccggcacaa cgtcccccaa
     5461 cccgtgctgg aataaggcgg gttcagacgg catattaggg gttttaatcc ccgtacggtc
     5521 attcggataa cagaccaagc atgtaagttt atgcccccat aagtacgctt ggcatagcag
     5581 taatattgtt cggttcagtg ttttccgttt gcccctatct gatactgcaa tatcagctat
     5641 gccgtctgaa aacgcatcat catgatattt tcagacggca taataaaaag cggaaatact
     5701 aatgcagggt aaaatgttcc attccgaatc ccataaatat acaatggctt atatcgttta
     5761 agcatgtgta acccaccctc atatcaatca atatatagtg gattaacaaa aaccagtacg
     5821 gcgttgcctc gccttgccgt actatctgta ctgtctgcgg cttcgtcgcc ttgtcctgat
     5881 ttttgtta
//
LOCUS       DAXIDM010000111         5659 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000111 DAXIDM010000000
VERSION     DAXIDM010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5659
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.111"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            98..814
                     /locus_tag="ACFOAE_001752"
     CDS             98..814
                     /locus_tag="ACFOAE_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFC6885194.1"
                     /translation="MNFENDDIIHAPTTSSLILEERHDSELFRVYALILDGITDQVLL
                     PGKKLTESELCRQMVCSRNTVRGALSLLAHDKIVDLQPNRGAFVHVPDLKEMQDVFNA
                     RIEMETMILNILADLPDLETRLKPLYAMIRREEEASGRGDRVGWNRLSNAFHVELARL
                     VGNDVLFDIMNTLCARSSLIVAVAGVHREEKHAINTHTHSEHREILDLLLAGRRNRVV
                     KILRRHLGNCMERLEKTLED"
     gene            963..1865
                     /locus_tag="ACFOAE_001753"
     CDS             963..1865
                     /locus_tag="ACFOAE_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter LysO family protein"
                     /protein_id="HFC6885195.1"
                     /translation="MDSLMTLLSVLIPMFAGFFIRVPKPYLPALDKVLSVLVYAVLLL
                     IGVSLSRVEDLGSRLDDMALTVLWLFVCTVGANLLALAVLGKLFPWRIKGKGKGVSVG
                     VSGSVGQLGCVLLGFASGKLMRDIWMPSESAGMYCLMLLVFLIGVQLKSSGVSLRQVL
                     VNRRGIRLSVWFMLSSLSGGLLFAASADGVSWVKGLAMASGFGWYSLSGLVMTEAYGA
                     VWGSIALLNDLARELFALAFIPLLMKRFPDAAVGVGGATSMDFTLPVIRGAGGLEAVP
                     VAVSFGVVVNIAAPFLMVVFSALG"
     gene            1908..2681
                     /locus_tag="ACFOAE_001754"
     CDS             1908..2681
                     /locus_tag="ACFOAE_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFC6885196.1"
                     /translation="MKPKIQRHGEILSLVRRHQFMSVDELAATLDVTPQTIRRDIREL
                     EDAGSLKRHHGGASSGGNLPEGLPASRQIQCQNEKNAIARLIAEHIPDESSLFVSIGT
                     TMEAVASELVRRRGSLRVITNNIHAASIASARTDYTVIITSGVVRPLDGGITGVATVD
                     FINQFKVDYAVMSTHGVESDGSLLDDDYKEVSVMQAMIANARVRFLGVDHSKFRSNAL
                     VRLGDITAFDKVFTDRLPDTAMQKMLKEAGVECLIADAV"
     gene            2793..4481
                     /locus_tag="ACFOAE_001755"
     CDS             2793..4481
                     /locus_tag="ACFOAE_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004819 - glutamine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006425 - glutaminyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HFC6885197.1"
                     /translation="MLNKDQFADNHFIRTIIEDDLKSGKHEAVQTRFPPEPNGYLHIG
                     HAKSICLNFGLAYIYDGLCNLRFDDTNPEKENDEYVNAIKEDVEWLGFHWAGEPRFAS
                     NYFDQLYDYAVGLIKDGKAYVDDLTPEEMREYRGTLTEAGKNSPYRDRSIEENLDLFT
                     RMKNGEFPDGSKTLRLKIDMASGNINMRDPVIYRIRRAHHHNTGDKWCIYPMYDYTHC
                     ISDAIEGITHSLCTLEFEAHRPLYDWVLDNIPAPHATRPRQYEFSRLELLYTITSKRK
                     LNQLVVEKHVSGWDDPRMPTISGMRRRGYTPEGLRLFAKRAGISKSENIVDMSVLEGA
                     IREELENSAPRLMAVLNPLKVTLTNFETGRTQSRRAAFHPNHEEMGEREVPISQTIYI
                     EADDFAENPPKGFKRLIPGGEVRLRHGYVIKCDEVVKDEAGNVVELKCSIDHDTLGKN
                     PEGRKVKGVIHWVSAEHAAEIKVRLYDRLFTVERPDAVRGEDGEYLPFTDFLNPESVK
                     EITAYAEPAAKDLPAESRWQFERIGYFVTDRKDHGKDTPVFNRTVTLKDSWQPK"
     gene            4574..5530
                     /gene="gshB"
                     /locus_tag="ACFOAE_001756"
     CDS             4574..5530
                     /gene="gshB"
                     /locus_tag="ACFOAE_001756"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004363 - glutathione synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HFC6885198.1"
                     /translation="MKVLFIADPMASFKTYKDTTYAMMREMAKRGWRLFHTLSGELSV
                     KNGLVVADASAFEFLGAQDDHDKNWFAAADKVQTVLKAFDAVIMRTDPPFDMQYLYAT
                     QLLTLAEQQGAKVFNSGQSMRDFNEKLAILNFSRFTAPTLVTTRSADVRAFLKEHGDI
                     IIKPLDGMGGMGIFRLTEKDPNIGSILETLMRLDSRTIMAQRYIPEIVHGDKRILIIG
                     GEVVPYALARIPQNGETRGNLAAGGRGVAQELDGRDREIAETLAPELKRRGILLAGLD
                     VIGSNLTEVNVTSPTGFQEIMKQKGFDVAAMFADAVAAWSVR"
BASE COUNT         1311 a         1533 c         1571 g         1244 t
ORIGIN      
        1 aatttgtgca atgctttaat ttccccgaca cgatttgaaa cacagccgcc ttaaaacatc
       61 ttaagaaatt tgaaagcgta aaaatacgga aaacatcatg aactttgaaa acgacgacat
      121 tatccatgcg ccgaccacgt cttccctgat tctcgaagag cggcacgatt cggagctgtt
      181 ccgtgtttac gccctgattt tggacggcat taccgatcag gtgctgctgc ctggcaaaaa
      241 gctgaccgaa tccgaacttt gccgccagat ggtgtgttcg cgcaacaccg tccgcggcgc
      301 gctgtcgctt ttggcgcacg acaagattgt cgatttgcaa cccaacaggg gcgcgttcgt
      361 ccacgttccc gatttgaaag aaatgcagga tgtgttcaat gcgcgcatcg aaatggagac
      421 gatgattttg aatatcctcg cagatttgcc ggatttggaa acgcgcctca agccgcttta
      481 tgcgatgata aggcgcgaag aagaggcttc cggcaggggc gaccgcgttg gctggaaccg
      541 cctgtccaat gcctttcacg tcgaactggc gcgcctggtg ggcaacgatg tgctgttcga
      601 cattatgaac acgctgtgcg cgcggtcttc cctgattgtc gccgtggcgg gcgtgcatcg
      661 cgaggaaaaa cacgccatca atacgcatac gcattccgaa caccgcgaaa tcctcgacct
      721 gctgctggcg ggcaggcgca accgcgtggt caaaatcctg cgccgccatt tgggcaactg
      781 tatggagcgt ttggaaaaga ctttggaaga ttgaatgccg gagcggataa gccgcctgaa
      841 ccttcaggcg gttttttaat ggcgaacctg atgccgtctg aaatatggat gcgggtatct
      901 gcaattttca gacggcaatt tttaaaccgc acatatcatg cggcaataaa ggagggcagt
      961 agatggacag cctgatgaca ttgctttcgg tattgatacc gatgttcgcc ggatttttta
     1021 tccgtgtgcc caagccttac ctgcccgctt tggataaggt gctatcggtc ttggtgtatg
     1081 ctgtgctgct gctgatcggt gtctcgttgt cgcgcgtgga ggatttgggt tcgcggttgg
     1141 acgatatggc gttgacggtt ctgtggctgt ttgtttgtac ggtcggggcg aacctgcttg
     1201 ctttggcagt gttgggaaag ttattcccgt ggcggataaa ggggaaaggg aagggcgttt
     1261 cggtcggtgt gtcgggcagt gtggggcagc tcggatgcgt gctgctcgga tttgcatccg
     1321 gcaaactgat gcgcgatatt tggatgccgt ctgaaagcgc gggcatgtat tgtctgatgc
     1381 tgctggtgtt cctcatcggc gtacagctca aaagcagcgg cgtatcgttg cggcaggttt
     1441 tggtcaaccg caggggtatt cggttgtcgg tatggtttat gctttcatct ctttcaggcg
     1501 ggctgctgtt tgccgcatcg gcagacggtg tgtcgtgggt gaaaggtttg gcgatggctt
     1561 ccggcttcgg ttggtattcc ctctcgggtt tggtgatgac cgaggcttac ggcgcggtat
     1621 ggggcagtat cgcgcttttg aacgatttgg cacgagagct gttcgcgctg gcatttattc
     1681 cgctgctgat gaagcgtttt cccgatgcgg cagtgggggt cggcggcgcg accagtatgg
     1741 atttcacatt gcccgtgatt cggggtgcgg gcggcttgga agccgtaccg gtagcggtca
     1801 gcttcggcgt ggtggtcaat atcgccgctc cgtttctgat ggtggtgttt tccgctttgg
     1861 gctgaacgcg gtaaaatcgg catcccgatg caaggaggca gaaaacgatg aaaccgaaaa
     1921 tccaaaggca cggagagatt ttaagccttg tccgccggca tcagtttatg tcggtggacg
     1981 agcttgccgc cacattggac gttaccccgc agacgatacg ccgcgacatc cgcgaattgg
     2041 aggatgctgg cagcctgaaa cgccaccacg gcggcgcatc ctcgggcgga aacttgccgg
     2101 aggggctgcc tgccagccgc caaattcaat gtcaaaacga aaaaaacgcc attgcccggc
     2161 tgattgcgga acatattccc gacgagtcat cgctgtttgt cagtatcggc acgacgatgg
     2221 aagccgtggc atcggagctg gtgagacggc gcggcagcct gagggtgatt accaacaata
     2281 tccacgccgc ctcgattgct tcggcgcgga cggattatac ggtcattatc acttccggag
     2341 tcgtccgccc tttggacggc ggtattaccg gcgtggcaac cgtcgatttt atcaaccagt
     2401 tcaaagtcga ttatgccgtg atgagtacgc acggcgtgga aagcgacggt tcgcttttgg
     2461 acgacgacta caaagaagtc agcgtgatgc aggcgatgat tgccaacgcg cgcgtccgct
     2521 tcctcggcgt ggaccacagt aaattccgca gcaacgcgct ggtcaggctc ggcgacatta
     2581 cggcgtttga caaagtattt accgaccggc tgcccgatac cgcgatgcag aagatgctga
     2641 aagaggcggg ggtggaatgc ctgattgccg atgccgtctg aacgctatgt caaagcgcgc
     2701 aagtcgggta caataaacac atcatcaaac cgcttcagac ggcataagga accgccccaa
     2761 tgccgtctga agccatctgt tcaaagaaaa ctatgctcaa taaagaccaa tttgcggaca
     2821 accattttat ccgcaccatc atcgaagacg acctcaaaag cggcaaacac gaagccgtcc
     2881 aaacccgttt tccgccggag cccaacggct acctgcacat cggacacgcc aaatccatct
     2941 gcctgaactt cggtttggcg tatatttacg acggcttgtg caacctgcgt tttgacgata
     3001 ccaaccccga aaaagaaaac gacgaatacg tcaacgccat caaagaagat gtcgagtggc
     3061 tcggtttcca ttgggcgggc gagccgcgtt tcgcttccaa ctatttcgac cagctttatg
     3121 actacgccgt cggtttgatt aaagacggca aagcgtatgt cgatgatttg acgccagaag
     3181 aaatgcgcga ataccgcggt acgctgaccg aagcaggcaa aaacagccct tatcgcgacc
     3241 gcagtatcga agaaaacctc gacctgttca cgcgcatgaa aaacggtgag ttccccgacg
     3301 gcagcaaaac cctgcgcctg aaaatcgaca tggcatccgg caacatcaat atgcgcgatc
     3361 cggtcatcta ccgcatccgc cgcgcccatc accacaacac cggcgacaaa tggtgcatct
     3421 atccgatgta cgactacacg cattgcattt ccgatgccat cgaaggcatc acgcattcct
     3481 tgtgtacgct cgaatttgaa gcccatcgtc cgctgtatga ctgggtgttg gacaacatcc
     3541 ccgcgccgca cgccacacgt ccgcgccaat acgagttttc acgcttggag cttttgtaca
     3601 ccattacctc caaacggaaa ttgaatcagt tggttgtgga aaaacacgtt tccggctggg
     3661 acgatccgcg tatgccgacc atttccggta tgcgccgacg cggctacacg cccgaagggc
     3721 tgcgcctgtt tgccaaacgc gccggtattt ccaaatctga aaacatcgtc gatatgagcg
     3781 tgttggaagg cgcgattcgc gaagagttgg aaaattccgc cccacgcctg atggcggtgt
     3841 tgaacccgct caaagtgacc ctgaccaact ttgaaaccgg cagaacccaa agccgccgtg
     3901 ccgcgttcca tccgaaccac gaggaaatgg gcgagcgcga agtacctatt tcacaaacca
     3961 tctatattga agccgacgac tttgccgaaa atccgcccaa aggcttcaaa cgcctgattc
     4021 ccggcggcga agtacgcttg cgccacggct atgtcatcaa gtgcgatgaa gtcgtcaaag
     4081 acgaagcagg caatgtggtt gaactcaaat gcagcatcga ccacgacacc ttgggcaaaa
     4141 atccagaagg ccgtaaagtt aaaggcgtga ttcattgggt ttccgccgaa cacgccgccg
     4201 aaatcaaagt ccgtctgtac gaccgcctct ttaccgtcga gcgtcccgat gccgtgcgcg
     4261 gcgaagacgg cgaatacctg ccgttcaccg atttcctcaa tccggaatcc gtcaaggaaa
     4321 tcaccgccta cgccgaacct gccgccaaag atttgccggc agaaagccgt tggcagttcg
     4381 agcgtatcgg ctacttcgta accgaccgta aagaccacgg caaagacacg ccggtgttta
     4441 accgcacggt cacgctgaaa gattcttggc agcctaagta aaaccccatc cttgccgtct
     4501 gaatattgtt cgggcggcat ttcccctttg cccgcgaaat gcggcacatt cggcacaccg
     4561 gaaaggaaat atgatgaaag tcctctttat cgccgacccg atggcaagtt tcaaaaccta
     4621 caaagacacc acctacgcca tgatgcgcga gatggcaaaa cgcggttggc ggctgtttca
     4681 taccttgagc ggggaattgt cggttaaaaa cggtctggtg gttgctgatg cgtctgcttt
     4741 tgagtttctc ggcgcacaag acgaccacga caaaaactgg tttgccgccg ccgacaaagt
     4801 tcagacggta ttgaaagcat ttgatgccgt gattatgcgt accgatccgc cgttcgatat
     4861 gcaatacctc tacgccaccc aattactgac gctggcggaa cagcagggcg cgaaagtctt
     4921 taacagcgga cagtcgatgc gtgacttcaa tgaaaaactg gcgattttga acttcagccg
     4981 ctttaccgcg cccacgctgg taacgacccg ttccgccgat gtccgcgcat ttttgaaaga
     5041 acacggcgac attatcatca aaccgctgga cggtatgggc ggtatgggta ttttccgcct
     5101 gaccgaaaaa gaccccaaca tcggcagcat cctcgaaacc ctgatgcggc ttgattcccg
     5161 caccattatg gcgcaacgct acattcccga aatcgtacac ggtgacaaac gcatcctgat
     5221 tatcggcggc gaagtcgtcc cctatgcttt ggcgcgtatc ccgcaaaacg gcgaaacacg
     5281 cggcaacctt gcggcaggcg gacgcggcgt ggcgcaggaa ttggacggac gcgaccgcga
     5341 aattgccgaa acgctcgccc ccgaactcaa acggcgcggc atcctgctgg ccggtttgga
     5401 cgttatcggc agcaacctga ccgaagtcaa cgtaaccagc ccgaccggat tccaagaaat
     5461 tatgaaacaa aaaggtttcg acgtggcggc aatgtttgcc gatgccgttg ccgcgtggtc
     5521 ggtacgttaa accgatgccg tttgaaaggc ttttgcttca caaccgtttg gtttgttcgg
     5581 gcaggcaggg ttttccctca gccggcaggg atgcggttaa tgccgtacgg acaccccgcc
     5641 gccccgtttt cagacggta
//
LOCUS       DAXIDM010000112         5650 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000112 DAXIDM010000000
VERSION     DAXIDM010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5650
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.112"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(430..3180)
                     /gene="tbpA"
                     /locus_tag="ACFOAE_001757"
     CDS             complement(430..3180)
                     /gene="tbpA"
                     /locus_tag="ACFOAE_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein TbpA"
                     /protein_id="HFC6885199.1"
                     /translation="MQQQHLFRFNILCLSLMTALPVYAENVQAGQAQEKQLDTIQVKA
                     KKQKTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIR
                     GMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSV
                     EQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEA
                     LLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDGSEYAYFIVEDECEGKNYETCKSKP
                     KKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHT
                     QQTFDTRDMTVPAFLTKAVFDENRKYGPIRGNGKYAGNHKYGGLFTNGENGALVGAEY
                     GTGVFYDETHTKSRYGLEYVYTNADKDTWVDYARLSYDRQGIGLDNHFQQTHCSADGS
                     DKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSN
                     LRHQDYYHQSANRAYSSNTPPQSGNGGSNANPNGSKDKPYWVSIGGGNVVTGQICLFG
                     NNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRT
                     LSWNAGIVLKPADWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAG
                     IVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKETAKGDPAYLNAQSARITGINVL
                     GKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGY
                     DQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYT
                     IKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEM
                     KF"
     gene            complement(3266..5374)
                     /locus_tag="ACFOAE_001758"
     CDS             complement(3266..5374)
                     /locus_tag="ACFOAE_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC6885200.1"
                     /translation="MNNPLVNQAAMVLPVFLLSACLGGGGSFDLDSVDTEAPRPAPKY
                     QDVSSEKPQAQKDQGGYGFAMRFKRRNWYQRANPKEDEIKLSEDDWEQTDDGDIKNPS
                     KQKNIINALPGNNEGALLQDSSQENQGISKVKDYHNFQYVWSGFFYKQIKNTIEKNGL
                     SITAARNGPDGYIFYKGKDPSRQLPVLGQVTYKGTWDFLTDVKINQKFIDLGNTSTRP
                     GDRYSAFSGELDYIVNKDSDKKDGHVGLGLTTEITVDFEKKTLSGKLIKNNSVTNNDK
                     YTTQYYSLEAQVTGNRFSGTATATDKPQNSETKEHPFVSDSSSLSGGFFGPQGEELGF
                     RFLSDDQKVAVVGSAKTKDKPANGNTAEASGGAGAAASGGAAGTSSENSKLTTVLDAV
                     ELKLGDKEVQKLDNFSNAAQLVVDGIMIPLLPQNSTGENNQPDQGKNGGTDFTYTTTY
                     TPESDKKDTQAQTGAGGAQAASGAAGVNGGQAGTKTYEVEVCCSNLNYLKYGMLTRKN
                     SKSAMQAGGNSSQADAKTEQVEQSMFLQGERTDEKEIPNDQNVVYRGSWYGHIANNTS
                     TSWSGNASNATSGNRADFTVNFGDKKITGTLTANDRTQPTFTITANIKDNGFEGTAKT
                     AELGFDLDQSNTTGTPKAYITNAKVQGGFYGPKAEELGGWFAYPGDKQTENTTVASGN
                     GNSASSATVVFGAKRQKPVQ"
BASE COUNT         1212 a         1436 c         1372 g         1630 t
ORIGIN      
        1 caaaaaaacc gaaaccgaac ggtctagatt cccgcctgcg cgggaatgac gaatccatcc
       61 atacggaaac ctgcatcccg tcattcctac gaacctacat cccgtcattc ccacgaaagt
      121 gggaatccag ttttttgagt ttcagtcatt cccgataaat tgccttagca ttgaatgtct
      181 agattcccac tttcgcggga atgacgggat ttgaggtttc tgtttttgat tttctgtttt
      241 cgcgggaatg acggtttaga agttacccga aacctcaaaa aaacctaaac cgaacggtct
      301 agattcctgc ctgcgcggga atgacgaatt tcaagattac ggtattgtcg gggatgatgg
      361 aaaacggtgg gaattgtgta aaaaatgccg tctgaagcct ttcagacggc atttgcggcg
      421 tttggacgtt taaaacttca tttccaagct aaatgtgtag tttcggccgg gggcggcata
      481 tcggttgtaa acgccgacat ttttgtgttg attgactgcg ccgccggcag tttgccgcac
      541 attttcccaa gtaacatagc ggtagttgag gaggttgtac acgcccgcac ggagggtgaa
      601 gtgtttttta atcgtgtaat aaccggacac atccacaata taccaagggc gggtacggcg
      661 tgcggtggct tttgtattgc ggctgttgcc gttgagcaaa gcccggctgc ccaacaactc
      721 tgtgatttcc ttggctttgg aataagtcag cataccgttc acaccccatt tgccttccgg
      781 ttggtcatag cccaagccga cgacatagcg cgagggttgg atggcatcaa acaggtgtga
      841 ttgaatatcg gtgcggtctg cgcgtttttt gatgtcgcgg acacggacac gattataggc
      901 aaatgtagaa taccaacctt cgggcaattt atcccatacg ccgttccaat cgattttgcc
      961 caaaacattg atgccggtaa tccgcgcgct ttgggcattg aggtaagccg ggtcgccttt
     1021 ggctgtttct ttgccgtctt taatttgcgc ttcataaccc cggacaatca aatcgcggta
     1081 ggcattgttg aaccaacttg cctccaagtt gccgaaatcg cctttaaaca cgatgccggc
     1141 ttctttgttg aacgattttt ccggatcgat tttgaccgcc ttgctttgaa cacccgcccg
     1201 ccagccgtac atttccgcaa acgagggcag gcggaagccg gttgaagtgc ggtaagtcaa
     1261 atccagccag tcggcaggtt tgaggacgat gccggcgttc caggacaggg tgcggtgcgt
     1321 gccggtggaa acgctgccgt cgtccgaatg cgtgctgcgg tagtcgtagc gcaagcccgc
     1381 gccgacatcc gcccacctgc ccaaacggac attgtcccga actgccgcgt aatagctttt
     1441 gccgttgatg ctgcgcggcg tgcagtccgt ataagtattg ttgccaaaga ggcagatttg
     1501 ccccgtaacc acatttcccc cgcctatgct gacccaatag ggtttgtcct tgctgccgtt
     1561 ggggttggcg tttgagccgc cgttgccgct ttgagggggc gtgttcgacg aataggcgcg
     1621 gttggcactt tgatgataat aatcctgatg gcggagatta gagccaaagc ggtcaaaccc
     1681 gagattcacg ctcaggttgt ggcggatttt ggcggtatcg aaggattttt tgaatgccgc
     1741 ctgcaagagc ctgtggcttt ccccgtaaat cacgcggtcg gatttgtagt aggaaaacgg
     1801 cttgtcggca ctcgggcggc aatatttgtc cgaaccgtcg gcagaacagt gcgtctgctg
     1861 aaaatgattg tccaaaccga tgccctgccg gtcgtaagag aggcgggcat aatccaccca
     1921 agtgtcttta tcggcattgg tatagacata ttccaaaccg tagcggcttt tggtgtgcgt
     1981 ctcgtcgtaa aacacgcccg taccgtattc cgcgcccacc agcgcaccgt tttcgccgtt
     2041 ggtaaacagt ccgccgtatt tgtggttgcc cgcgtatttg ccgttgcctc ttatcggtcc
     2101 gtattttcta ttttcatcaa aaaccgcctt ggtcaggaat gccggaaccg tcatatcgcg
     2161 cgtgtcgaaa gtttgttgcg tgtgttcgag tatgccgccg atgtagtgcc gtttgttttc
     2221 aaaacgaaaa cccgggcgga acagccacga ccggctttcg tatgaaagcg gatcggcaag
     2281 gaagcggttg ggacccgtgt agtctcgggt ggaaaccgtt tgacgttcgt ctttgccgac
     2341 aacatctttt ttcggtttgc ttttacacgt ttcgtaattt ttgccttcgc attcatcttc
     2401 aacgatgaaa taggcgtatt cgctgccgtc ttcaaccggc accagcctgt taaagctctg
     2461 aacgccgcgt cctgcatctt cgtgggcgcg gatttccccc gcgcgccgcc cggtgtggat
     2521 cagcaaagcc tccgcaccgc cgatgcgccc cgccagcgcg atggattggg taagcccccg
     2581 gtttttgccg gaataggcgg ttttactctg aatcccccac tgcctgcctt ccccgataac
     2641 atcgtcggcg gttttggttt gaaatgcgac cgaacccgcc aatgcgccgc tgccttgttc
     2701 gaccgagttt gagcctttgc tgatttcgac agctttgacg ttttcatact cgatttcatt
     2761 gattgcgccg ctgctgcccg ccgtcctcgt cccgcccaat gccgcctgcg cggtgtagga
     2821 ctgtatttgc gaaacgccgt ctaccgttaa ggaaacgcgg tttttatcca taccgcgtat
     2881 tgaatagccc gagcttgcgc cgcgcccctg ttcgaccacg gcgatgccgg ggtcgtaacg
     2941 cgtcaggtcg cggatatcga gtacctgttc cttgctgagg gtgtcggcgg ttttgaccaa
     3001 tttacccaaa ccggttactt cgttatcccg gcgggttttc tgttttttgg cttttacctg
     3061 tatggtatcc aactgttttt cctgtgcttg tccggcttgc acattttctg cataaacggg
     3121 cagcgcagtc attaaagaca ggcataaaat attgaatcgg aacaaatgtt gctgttgcat
     3181 agtgtttccc taatcttcgc tttcagacgg tatcggaagg agcgatgccg tcgaagcctt
     3241 attcttgatt gttcggcaac cgtgcttatt gcacaggctt ttggcgtttc gcaccgaata
     3301 cgacagttgc actgcttgct gaatttccat tgccggatgc aactgttgta ttttccgttt
     3361 gtttatcgcc cggataggca aaccatccgc ccaactcttc ggctttaggt ccgtaaaaac
     3421 cgccctgcac cttggcgttt gtgatatatg ccttaggcgt gccggtggta ttgctttgat
     3481 cgagatcaaa acctaattca gcagtttttg ccgtaccttc aaagccgttg tccttaatat
     3541 tagccgtgat agtaaaggtt ggctgagtcc tatcattagc ggttaacgtg ccggtaattt
     3601 ttttatcgcc aaaattcacg gtaaagtccg ccctgttgcc actcgttgca ttggaagcat
     3661 tgccgctcca gcttgtgctt gtgttgttgg caatatgccc gtaccaagac ccccgataaa
     3721 cgacgttttg gtcgtttgga atctcttttt catcggtacg ctcgccttgg aggaacatac
     3781 tttgttcaac ttgttccgtt ttagcatcag cttgactact gtttcctcct gcctgcatcg
     3841 cggacttgct gtttttacgc gtcaacattc cgtatttcag ataattgagg ttggaacagc
     3901 agacttcaac ttcataggtt tttgttcctg cctgcccgcc gttaacgccc gccgcacccg
     3961 aagcagcttg cgcgccgccc gcgcctgttt gggcttgggt gtctttttta tcactttccg
     4021 gcgtgtaggt tgttgtgtag gtaaagtctg tcccgccgtt tttaccttga tcgggctgat
     4081 tattttcgcc tgttgaattt tgaggcaaga gcggaatcat aatgccgtcg acaaccagtt
     4141 gggcggcgtt gctgaagttg tcgagctttt ggacttcctt atcgcccaat ttcagctcga
     4201 ccgcatccaa aaccgtggtc agcttactgt tttcagacga cgtgcctgcc gcaccgcccg
     4261 atgctgccgc acctgcgccg cctgaagcct ccgcagtatt gccatttgcg ggtttgtctt
     4321 tggttttcgc gctgccgaca accgcaactt tttgatcgtc gctcaaaaag cggaaaccca
     4381 attcctcacc ctgcgggccg aaaaagccgc cgctcaaaga agacgaatcg gaaacaaagg
     4441 gatgttcctt ggtttcgctg ttttggggtt tgtcggttgc cgttgccgtg ccgctgaaac
     4501 ggttgcctgt tacttgagcc tcaaggctgt aatattgggt ggtgtattta tcgttattag
     4561 tgacactgtt gtttttaatt aattttccgc tgagggtttt tttctcaaaa tcaaccgtta
     4621 tttccgttgt taatcccaaa cctacgtgcc cgtctttctt atcgctatct ttattgacga
     4681 tataatccaa ctccccggaa aaagcactat atcggtcgcc gggtctcgta gaagtattcc
     4741 ctaaatctat aaatttctga tttattttca catcagttaa gaaatcccaa gtccctttat
     4801 acgtaacctg tcccaataca gggagttgtc tcgagggatc tttgccttta taaaaaatat
     4861 aaccgtcagg accatttctg gctgcggtta tagataagcc gtttttttca attgtatttt
     4921 taatctgttt ataaaaaaaa cccgaccata cgtattggaa attgtgatag tccttaacct
     4981 tagatatacc ctgattttct tgactggaat cttgcaataa tgctccttca ttatttccag
     5041 gtaaggcatt aataatattt ttttgtttgg aagggttttt gatatcacca tcatccgttt
     5101 gttcccaatc atcttcagag agttttatct catcttcttt aggattcgcc ctctgatacc
     5161 aattccgccg cttgaagcgc attgcaaaac cgtatccgcc ttggtctttt tgggcttgcg
     5221 gtttttcgga agaaacatct tgatattttg gcgcgggacg cggggcttcg gtatcgacag
     5281 aatcaagatc gaaactgccg cctccgccca aacaagcact caacaaaaac acaggcagca
     5341 ccatagcagc ctgattcacc aatggattgt tcataataaa tccaattcaa ttaaagaatg
     5401 ataaggatta ttattttatt tatttttaac aaatttgcaa atactttttt atttttttag
     5461 ggaatacacc aaaatcccgt cattcccacg aaagtgggaa tccgaacgcg tccgcacgga
     5521 aacctatatc ccgtcattcc cacgtatatc ccgtcattcc cgcgcaggcg ggaatccagt
     5581 gcgttgagtt tcagctattt agaataaatt ttgaaactct aatcgcgtca ttcccacgaa
     5641 agtgggaatc
//
LOCUS       DAXIDM010000113         5648 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000113 DAXIDM010000000
VERSION     DAXIDM010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5648
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.113"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(103..864)
                     /locus_tag="ACFOAE_001759"
     CDS             complement(103..864)
                     /locus_tag="ACFOAE_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885201.1"
                     /translation="MDANKEPNWEKRLENLRQTRRMKAVPTYAPLSRPSETGTDAPVP
                     KLDDESRARVLKAYLKKWQEEHNAAVADCGEEVETDPMIVLQENWLNAQASLQMSVSE
                     KHIESRRRILFDAKKDSAEFETGQIEGGENADAAESGTAADGVAENGEGGAEEALMPV
                     QINILNPKAVNRREVFCLSEQELTERLIKRLRPHLTDTVNGIIRTAVQKQMAVFTYQL
                     QQMLHEQAGAVVEDVLEHDVRKILNDIKYELKYKR"
     gene            963..1214
                     /locus_tag="ACFOAE_001760"
     CDS             963..1214
                     /locus_tag="ACFOAE_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885202.1"
                     /translation="MGSIEQRLEYLEEANDVLRMQNHVLSTAFKALIRALPAETAEIA
                     VESIQLAFEDALAELSYEDSPHTDLFHDVTYAFFREKER"
     gene            1266..2072
                     /locus_tag="ACFOAE_001761"
     CDS             1266..2072
                     /locus_tag="ACFOAE_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="HFC6885203.1"
                     /translation="MNMKKWIAAALACSALALSACGGQGKDAAAPAANPDKVYRVASN
                     AEFAPFESLDSKGNVEGFDVDLMNAMAKAGNFKIEFKHQPWDSLFPALNNGDADVVMS
                     GVTITDDRKQSMDFSDPYFEITQVVLVPKGKKISSSDDLKNMNKVGVVTGYTGDFSVS
                     KLLGNDNPKIARFENVPLIIKELENGGLDSVVSDSAVIANYVKNNPTKGMDFVTLPDF
                     TTEHYGIAVRKGDEATVKMLNDALEKVRESGEYDKIYAKYFAKEDGQAAK"
     gene            2379..3902
                     /locus_tag="ACFOAE_001762"
     CDS             2379..3902
                     /locus_tag="ACFOAE_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HFC6885204.1"
                     /translation="MTVIKQEDFIQSICDAFQFISYYHPKDYIDALYKAWQKEENPAA
                     KDAMTQILVNSRMCAENNRPICQDTGIATVFLKVGMDVQWDADMSVEEMVNEGVRRTY
                     TWEGNTLRASVLADPAGKRQNTKDNTPAVIHMSIVPGGKVEVTCAAKGGGSENKSKLA
                     MLNPSDNIVDWVLKTIPTMGAGWCPPGILGIGIGGTPEKAVLMAKESLMSHIDIQELQ
                     EKAASGAELSTTEALRLELFEKVNALGIGAQGLGGLTTVLDVKILDYPTHAASKPIAM
                     IPNCAATRHVEFELDGSGPVELTPPRVEDWPDLTYSPDNGKRVDVDKLTKEEVASWKT
                     GDVLLLNGKILTGRDAAHKRLVDMLNKGEELPVDFTNRLIYYVGPVDPVGDEVVGPAG
                     PTTATRMDKFTRQMLEQTDLLGMIGKSERGVATCEAIADNKAVYLMAVGGAAYLVAKA
                     IKSSKVLAFPELGMEAIYEFEVKDMPVTVAVDSKGESIHATAPPQWQAKIGIIPVES"
     gene            4000..5412
                     /gene="trkA"
                     /locus_tag="ACFOAE_001763"
     CDS             4000..5412
                     /gene="trkA"
                     /locus_tag="ACFOAE_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HFC6885205.1"
                     /translation="MKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRL
                     DVQTVFGNGASPFTLERAGAEDADLLLALSRSDETNIVACKVAADLFNIPGRIARVRS
                     SEYLEYLSPKLENNENGSLSIFGITETISPEQLVTEQLAGLIDCPGALQVLRFADDRV
                     RMVIIQARRGGLLVGRSIADIAQDLPDGADCQICAVYRNNRLIVPAPQTVIIEGDEIL
                     FAAAAENIGAVIPELRPKETSTRRIMIAGGGNIGYRLAKQLEHAYNVKIIECRPRRAE
                     WIAENLDNTLVLQGSATDETLLDNEYIDEIDVFCALTNDDESNIMSALLAKNLGAKRV
                     IGIVNRSSYVDLLEGNKIDIVVSPHLITIGSILAHIRRGDIVAVHPIRRGTAEAIEVV
                     AHGDKKTSAIIGRRISGIKWPEGCHIAAVVRAGTGETIMGHHTETVIQDGDHIIFFVS
                     RRRILNELEKLIQVKMGFFG"
BASE COUNT         1421 a         1695 c         1370 g         1162 t
ORIGIN      
        1 aatttaatcc actatattaa tattttgcgc ctgttctatg atgctttcaa gtcgggtgag
       61 aatgcaaatg ccgtctgaaa cggctttcag acggcatggc aatcagcgtt tgtattttaa
      121 ctcgtacttg atgtcgttga ggattttgcg gacatcgtgt tccaacacgt cttcgactac
      181 cgcacccgcc tgctcgtgca gcatctgctg gagctgatag gtaaaaaccg ccatctgctt
      241 ttgcaccgcc gtacggatga tgccgttgac ggtatcggtc agatgcgggc gcaggcgttt
      301 gatcagccgt tcggtcagct cctgttcgga caggcagaac acttcgcgcc ggttgacggc
      361 tttcggattc aggatattga tttggacggg catcaacgcc tcttccgcac cgccttcgcc
      421 gttttccgca accccgtctg ccgccgtacc cgattctgcc gcatcggcgt tttccccgcc
      481 ttcaatctgt ccggtttcaa attcggcact gtcttttttg gcatcgaaca ggattctccg
      541 ccgcgattcg atgtgttttt ccgaaaccga catttgcagg gaagcctgcg cgttgagcca
      601 gttttcctga aggacaatca tcgggtcggt ttcgacttcc tcgccgcaat cggcaacggc
      661 ggcattgtgt tcctcctgcc attttttcag atacgccttc aacacacggg ctcggctctc
      721 atcgtccagt ttcggcacag gcgcgtccgt tccggtttca gaggggcggg acagcggcgc
      781 gtaagtcggc actgccttca tacggcgcgt ctgacgcagg ttttccaaac gtttttccca
      841 attcggctct ttattcgcat ccattttcgg cttccggttc ttaatctttg caagcagaca
      901 aacccgcgcc caaagcgcgt ttgatataat cgcgcatttt aacagattcg cgaggataca
      961 tcatgggcag catcgaacag cgtttggaat atctggaaga ggcgaacgac gtgctgcgta
     1021 tgcagaacca cgtcctgtcc accgcattca aagccttaat ccgcgccctt cccgccgaaa
     1081 ccgccgaaat cgcggtcgag tcgattcagc ttgcttttga ggacgccttg gcagaattga
     1141 gctatgagga cagcccccat accgatttgt tccacgacgt tacttatgcg tttttccgtg
     1201 aaaaagaacg ttaattttat gttaaactga ttttttaggc tttttgatta ccgaaaggaa
     1261 ttttgatgaa tatgaaaaaa tggattgccg ccgcccttgc ctgttccgcg cttgcgctgt
     1321 ctgcctgcgg cggtcagggt aaagatgccg ccgcgcccgc cgcaaatccc gacaaagtgt
     1381 accgcgtggc ttccaacgcc gagtttgccc cctttgaatc tttagactcg aaaggcaatg
     1441 tcgaaggttt cgatgtggat ttgatgaacg cgatggcgaa ggcgggcaat tttaaaatcg
     1501 aattcaaaca ccagccgtgg gacagccttt tccccgcctt gaacaacggc gatgcggacg
     1561 ttgtgatgtc gggcgtaacc attaccgacg accgcaaaca gtctatggac ttcagcgacc
     1621 cgtattttga aatcacccaa gtcgtcctcg ttccgaaagg caaaaaaata tcttcttccg
     1681 acgatttgaa aaacatgaac aaagtcggcg tggtaaccgg ctacacgggc gatttctccg
     1741 tttccaaact cttgggcaac gacaatccga aaatcgcgcg ctttgaaaac gttcccctga
     1801 ttatcaaaga actggaaaac ggcggcttgg attccgtggt cagcgacagc gcagtcatcg
     1861 ccaattatgt gaaaaacaat ccgaccaaag ggatggactt cgttaccctg cccgacttca
     1921 ccaccgaaca ctacggcatc gcggtacgca aaggcgacga agcaaccgtc aaaatgctga
     1981 acgatgcgtt ggaaaaagta cgcgaaagcg gcgaatacga caagatttac gccaaatatt
     2041 ttgcaaaaga agacggacag gccgcaaaat aagcccgccc gtccgaacac aatgccgtct
     2101 gaagcctttt cagacggcat tgttcatcaa ccggcctaca atgaactgcc tgctgatttc
     2161 tccctaccgc aaagcaacag gcaaagatta caaatatcaa aatccgagta aaacagtatt
     2221 ttattaaaac aaattgataa tcaagagatt agaattatgt attgtcttta ccgtacaaac
     2281 gctggcacta tttcaacctg ataaaaaaca gccttcaaaa aggttgctta aaacagcagc
     2341 agacacttac cgccacaacc ttgaaaagga acacaatcat gaccgtcatc aagcaagaag
     2401 actttatcca aagtatctgc gatgccttcc aattcatcag ctactaccat ccgaaagact
     2461 acatcgacgc gctttataag gcgtggcaga aggaagaaaa tcccgccgcc aaagacgcga
     2521 tgacgcagat tttggtcaac agccgtatgt gtgcggaaaa caaccgcccc atctgccaag
     2581 ataccggtat cgcaaccgtg tttttgaaag tcggtatgga tgtgcagtgg gatgcggata
     2641 tgagcgtgga agaaatggtt aacgaaggcg tgcgccgcac ctacacttgg gaaggcaata
     2701 cgctgcgcgc ttccgttctc gccgaccccg ccggcaaacg ccaaaacacc aaagacaaca
     2761 cccccgccgt catccatatg agcatcgtgc cgggcggtaa agtcgaagta acctgcgcgg
     2821 caaaaggcgg cggctctgaa aacaaatcca aactcgccat gctcaatcct tccgacaaca
     2881 tcgtcgattg ggtattgaaa accatcccga cgatgggcgc gggctggtgt cctcccggca
     2941 tcttgggcat cggcatcggc ggcacgcctg aaaaagccgt gttgatggca aaagaatccc
     3001 tgatgagcca catcgacatt caagagttgc aggaaaaggc cgcgtccggc gcagaattgt
     3061 ccaccaccga agccctgcgc ctcgaactct ttgaaaaagt caacgcgctg ggcatcggcg
     3121 cacaaggttt gggcggtctg accaccgtgt tggacgtgaa aatcctcgat tacccgaccc
     3181 acgccgcctc caaaccgatt gccatgattc cgaactgcgc cgccacccgc cacgtcgaat
     3241 ttgaattgga cggctcaggc cctgtcgaac tcacgccgcc gcgcgtcgaa gactggcccg
     3301 atttgactta cagccccgac aacggcaaac gcgtcgatgt cgataagctg accaaagaag
     3361 aagtggcaag ctggaaaacc ggcgacgtat tgctgctgaa cggtaaaatc ctcaccggcc
     3421 gcgatgccgc acacaaacgc ctcgtcgata tgctcaacaa aggcgaagaa ttgcccgtcg
     3481 atttcaccaa ccgcctgatt tactacgtcg gtcccgtcga tccggtcggc gatgaagtcg
     3541 tcggtccggc aggtccgacc acagccaccc gcatggacaa attcacccgc caaatgctcg
     3601 aacaaaccga cctcttgggc atgatcggca aatccgagcg cggcgtggcc acctgcgaag
     3661 ccatcgccga caacaaagcc gtgtacctca tggcagtcgg cggcgcggcg tatctcgtgg
     3721 caaaagccat caaatcttcc aaagtcttgg cgttccccga attgggcatg gaagccattt
     3781 acgaatttga agtcaaagac atgcccgtaa ccgtcgccgt agacagcaaa ggcgaatcca
     3841 tccacgccac cgccccgccc caatggcagg cgaaaatcgg catcatcccc gtcgaatctt
     3901 gaggcgtcat gccgtctgaa cacaaaatct gctttcagac ggcatttccg cccccggttg
     3961 cggtacaatc caccatttca tcactcggcg acccacaccg tgaaaatcct cattttaggc
     4021 aacggacagg taggttctac cgtcgcacaa aaccttgccg ccatacccaa caacgacgta
     4081 accgttatcg acatcgacga aaaagcattg caggaaacag gcagccgcct cgatgtccaa
     4141 accgttttcg gcaacggcgc atcccccttc acattagaac gcgccggcgc ggaagatgcc
     4201 gacttgctgc tcgcgctctc ccgcagcgac gaaaccaaca tcgtcgcctg caaagttgcc
     4261 gccgacctgt tcaacatccc cggccgcatc gcgcgcgtcc gttccagcga atacctcgaa
     4321 tacctcagcc ccaagctcga aaacaacgaa aacggcagcc tttccatatt cggcataacc
     4381 gaaaccatca gccccgaaca gctcgttacc gaacagcttg ccggcctgat agactgcccg
     4441 ggcgcattgc aggttttacg ttttgcagac gaccgcgtgc ggatggtcat catacaggcg
     4501 cggcgcggcg ggctgcttgt cggacgcagc attgccgaca tcgcccaaga tttgcccgac
     4561 ggggccgact gccaaatctg cgccgtttac cgcaacaacc gcctcatcgt ccccgcgccg
     4621 caaaccgtca tcatcgaagg cgacgaaatc ctgtttgccg ccgccgccga aaacatcggc
     4681 gcggtcatac ccgaattgcg ccccaaagaa accagcaccc gccgcatcat gattgccggc
     4741 ggcggcaaca tcggctaccg tctcgccaag cagctcgaac acgcatacaa cgtcaaaatc
     4801 atcgaatgcc ggccgcgccg tgccgaatgg atagccgaaa acctcgacaa caccctcgtc
     4861 ctgcaaggtt cggcaaccga cgaaaccctg ctcgacaacg aatacatcga cgaaatcgac
     4921 gtattctgcg ccctgaccaa cgacgacgaa agcaacatta tgtccgccct tttggcgaaa
     4981 aacctcggcg cgaagcgcgt catcggcatc gtcaaccgct caagctacgt cgatttgctc
     5041 gaaggcaaca aaatcgacat cgtcgtctcc ccccacctca tcaccatcgg ctcgatactc
     5101 gcccacatcc ggcgcggcga catcgttgcc gtccacccca tccggcgcgg cacggcggaa
     5161 gccatcgaag tcgtcgcaca cggcgacaaa aaaacttccg ccatcatcgg caggcgcatc
     5221 agcggcatca aatggcccga aggctgccac attgccgccg tcgtccgcgc cggaaccggc
     5281 gaaaccatta tgggacacca taccgaaacc gtcatccaag acggcgacca catcatcttt
     5341 ttcgtctcgc gccggcgcat cctgaacgaa ctggaaaaac tcatccaagt caaaatgggc
     5401 tttttcggat aaaccgcccc attccggaca tattgccgcc aagcggtatg gaagcggaat
     5461 aatggtaggt gggcttcaga cggcatccgc cctccccgtc attcccgcgt aagcgggaat
     5521 ccagaccttg ggatagcggc aatattcaaa ggttagctga agctttagag attctagatt
     5581 cccgtttcca cgggaatgac gaaaggttgc gggaatccaa accattgggc aacagcaata
     5641 ttcaaaga
//
LOCUS       DAXIDM010000114         5626 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000114 DAXIDM010000000
VERSION     DAXIDM010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5626
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.114"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            50..2107
                     /gene="metG"
                     /locus_tag="ACFOAE_001764"
     CDS             50..2107
                     /gene="metG"
                     /locus_tag="ACFOAE_001764"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFC6885206.1"
                     /translation="MTRKILVTSALPYANGSIHLGHMVEHIQTDVWVRFQKLRGHECH
                     YCCADDTHGTPVMLAAQKQGIAPEDMIAKVREEHLADFTGFFIGYDNYYSTHSPENKQ
                     FSQDIYRALKANGKIESRVIEQLFDPEKQMFLPDRFVKGECPKCHAQDQYGDNCEVCG
                     TTYSPTELINPYSAVSGAKPELRESEHFFFKLGECADFLKAWTSGNNPHDGKPHLQAE
                     ALNKMKEWLGEGEETTLSDWDISRDAPYFGFEIPDAPGKYFYVWLDAPVGYMASFKNL
                     CDRIGVDFDEYFKADSQTEMYHFIGKDILYFHALFWPAMLHFSGHRAPTGVYAHGFLT
                     VDGQKMSKSRGTFITAKSYLEQSLNPEWMRYYIAAKLNSKIEDIDLNLQDFISRVNSD
                     LVGKYVNIAARASGFIAKRFEGRLKDVADSALLAKLTAQSEAIAECYESREYAKALRD
                     IMALADIVNEYVDANKPWELAKQEGQDARLHEVCSELINAFTVLTAYLAPVLPKVAEN
                     AAKFLNLEAITWANTRETLGKHAINKYEHLMQRVEQKQVDDLIEANKQSIAAAAAPAA
                     EESKYEKVAEQASFDDFMKIDMRVAKVLNCEAVEGSTKLLKFDLDFGFEKRIIFSGIA
                     ASYPNPAELNGRMVIAVANFAPRKMAKFGVSEGMILSAATADGKLKLLDVDTGAQPGD
                     KVG"
     gene            complement(2182..3135)
                     /locus_tag="ACFOAE_001765"
     CDS             complement(2182..3135)
                     /locus_tag="ACFOAE_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HFC6885207.1"
                     /translation="MNHKKIVVLDADTLPGRVFHFDFPHELAVYGTTGADETAERVHD
                     AHVVITNKVMISADIIAANPQLELIAVSATGVNNVDIGAAEAAGVAVCNVRAYGNESV
                     AEHAFMLMIALMRNLPAYQRDVAAGLWEKSPFFCHYGAPIRDLNGKTLAVFGRGNIGR
                     TLAGYAQAFGMGVVFAEHKHASAVREGYVSFEDAVRAADVLSLHCPLNAQTENMIGEN
                     ELRQMKPGAVLINCGRGGLVDENALLAALKYGQIGGAGVDVLTEEPPRGGNPLLNARL
                     PNLIVTPHTAWASREALDRLFDILLANIHAFVKGEAQNRVV"
     gene            3256..3390
                     /locus_tag="ACFOAE_001766"
                     /pseudo
     CDS             3256..3390
                     /locus_tag="ACFOAE_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218456.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2061 domain-containing protein"
     gene            complement(3481..3546)
                     /locus_tag="ACFOAE_001767"
                     /pseudo
     CDS             complement(3481..3546)
                     /locus_tag="ACFOAE_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3542..3628
                     /locus_tag="ACFOAE_001768"
                     /pseudo
     CDS             3542..3628
                     /locus_tag="ACFOAE_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218456.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2061 domain-containing protein"
     gene            3706..4019
                     /locus_tag="ACFOAE_001769"
                     /pseudo
     CDS             3706..4019
                     /locus_tag="ACFOAE_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215210.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
     gene            4048..4296
                     /locus_tag="ACFOAE_001770"
                     /pseudo
     CDS             4048..4296
                     /locus_tag="ACFOAE_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
     gene            4535..4870
                     /locus_tag="ACFOAE_001771"
                     /pseudo
     CDS             4535..4870
                     /locus_tag="ACFOAE_001771"
                     /inference="COORDINATES: protein motif:HMM:NF012342.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
     gene            4865..5284
                     /locus_tag="ACFOAE_001772"
     CDS             4865..5284
                     /locus_tag="ACFOAE_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
                     /protein_id="HFC6885208.1"
                     /translation="MPSTCRDAASAVCTKTPEYYLNHGKWPDGNSNAGVASSSTIKGK
                     KYVEKVEVAKGVITATMLSTGVNNEIKGKKLSLWAKRQDGSVKWFCGQPVKRDDANAK
                     DDVAAATGTDKIDTKLKKPFYPISFRTDRPGFPPARE"
     gene            5286..5626
                     /locus_tag="ACFOAE_001773"
                     /pseudo
     CDS             5286..5626
                     /locus_tag="ACFOAE_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
BASE COUNT         1581 a         1657 c         1277 g         1111 t
ORIGIN      
        1 tttgatttgc ggtataatcc gcctttaccc attgtttgca aagcacaata tgacacgcaa
       61 aatcttagtt acctccgccc tgccctatgc caacggcagc atccacctcg gccacatggt
      121 cgaacacatc caaaccgacg tttgggtgcg ctttcaaaaa ctgcgcggcc acgagtgcca
      181 ctactgctgc gccgacgaca cccacggcac gcccgtaatg cttgccgcgc aaaaacaagg
      241 tatcgcgccc gaagacatga ttgccaaagt gcgcgaagag cacctcgccg actttactgg
      301 ctttttcatc ggttacgaca attattacag cacccattcc cctgaaaaca aacagttttc
      361 ccaagacatt taccgcgcgc tgaaagccaa cggcaagatt gagagccgcg tcatcgagca
      421 gcttttcgac cccgaaaaac aaatgttcct gcccgaccgc ttcgttaaag gcgaatgccc
      481 gaaatgccac gcccaagacc aatacggcga caactgcgaa gtctgcggca cgacctattc
      541 cccgaccgaa ctgattaacc cgtattccgc cgtttccggc gcgaaacccg aattgcgcga
      601 atccgaacac ttcttcttca aactgggaga atgcgccgac ttcctcaaag catggacttc
      661 cggcaacaac ccgcacgacg gcaagcccca tctgcaagcc gaagccctca acaaaatgaa
      721 agaatggctg ggcgaaggtg aagaaaccac cctgtccgac tgggatattt cccgcgacgc
      781 gccgtatttc ggttttgaaa tccccgacgc gccgggcaaa tacttctacg tctggctgga
      841 cgcgcccgtc ggctacatgg cgtcgtttaa aaacctgtgc gaccgcatcg gcgtcgattt
      901 tgacgaatac ttcaaagccg acagccaaac cgagatgtac cacttcatcg gcaaagacat
      961 cctctatttc cacgccctgt tctggcctgc catgctgcat ttctccggcc accgcgcccc
     1021 gaccggcgtg tacgcacacg gctttttgac cgtagacgga caaaaaatgt ccaaatcgcg
     1081 cggcacgttt atcaccgcca aatcctatct ggaacaaagt ttaaaccccg agtggatgcg
     1141 ctactacatc gccgccaaac tcaacagcaa aatcgaagac atcgatttga acctgcaaga
     1201 ctttatcagc cgcgtcaaca gcgacctcgt cggcaaatac gtcaacatcg ccgcccgcgc
     1261 gtcaggtttc attgccaaac gctttgaagg ccgtttgaaa gacgtcgccg acagcgcatt
     1321 attggcaaaa ctgaccgcac aaagcgaagc cattgccgaa tgctacgaaa gccgcgaata
     1381 cgccaaagcc ctgcgcgaca tcatggcctt ggcggacatt gtcaacgaat acgttgatgc
     1441 caacaaacct tgggaactcg ccaaacaaga aggccaagac gcacgcctgc acgaagtatg
     1501 cagcgagctc atcaacgcct ttaccgtgtt gaccgcctac ctcgcccccg tattgccgaa
     1561 agtggccgaa aatgccgcca aattcctgaa tttggaagcc atcacttggg caaatacacg
     1621 cgaaaccttg ggcaaacacg ccatcaacaa atacgaacat ttaatgcaac gagtggagca
     1681 aaaacaagtg gacgatttga tcgaagccaa caaacaaagc atcgccgccg cagccgcacc
     1741 tgccgccgaa gagagcaaat acgaaaaagt tgccgaacag gcgagtttcg acgactttat
     1801 gaaaatcgac atgcgcgtcg ccaaagtatt gaactgcgaa gccgtcgaag gcagcaccaa
     1861 acttttgaaa ttcgacctcg atttcggttt tgaaaaacgc attatcttct ccggcatcgc
     1921 cgcgtcttat cccaaccctg ccgagttaaa tggaaggatg gtcatcgccg tcgccaactt
     1981 cgccccgcgc aaaatggcaa aattcggcgt atccgaaggc atgattttga gtgccgccac
     2041 ggcagacggg aaactgaagc tcttagatgt ggatacaggc gcgcagccgg gcgacaaagt
     2101 cggttaaaca ggaatctcaa gaaatgccgt ctgaaccctt gaggcgttca gacggcattt
     2161 ttttccgcaa tcccgacagg ttcaaaccac gcggttttgc gcctcgcctt tcacaaaggc
     2221 gtgaatgttc gccaacaata tatcgaacag cctgtccaac gcttcacgac ttgcccacgc
     2281 ggtatgcggc gtaacaatca gattgggaag tcgtgcattc agcaggggat tgccgcccct
     2341 tggcggctcc tccgtcaaaa catcgacacc agccccgccg atctgcccgt atttgagtgc
     2401 ggcaagcagc gcgttttcat ccaccagccc gccgcgccca caattgatta aaaccgcgcc
     2461 aggcttcatc tgccgcaatt cgttttcgcc tatcatattt tcagtttggg cgtttagcgg
     2521 acagtgcagc gacaacacat cagcagcccg taccgcatct tcaaaggaaa catagccttc
     2581 gcgcacagcg gacgcgtgtt tgtgttcggc aaacaccacc cccataccga atgcctgcgc
     2641 gtatccggca agcgtccgtc cgatattgcc gcgtccgaaa accgccagcg ttttgccgtt
     2701 caaatcccga atcggcgcgc cgtaatggca gaaaaacggc gacttttccc acaaaccggc
     2761 cgcaacatca cgctgatagg caggcagatt ccgcattaac gcaatcatca gcataaaggc
     2821 gtgttccgca accgattcgt ttccgtaggc gcggacattg cataccgcaa cgcccgccgc
     2881 ctccgccgcc ccaatatcga cattgttcac accggtcgca ctgacggcaa tcagctccaa
     2941 ctgcggatta gccgcaataa tgtcggcgga aatcattacc ttattggtaa tgacaacatg
     3001 tgcgtcgtgc acccgttctg ccgtttcatc cgcacctgtc gtaccgtaaa ctgcgagctc
     3061 gtgcggaaaa tcaaaatgaa aaacccggcc gggcaaagta tccgcatcca aaacaacgat
     3121 ctttttatga ttcataattt ctatccccat ttaaaaaatg atttatttac actaacaaca
     3181 aatagcaaat ttaaaccgcg cagccttatg ataatcttta tcatctatcc gtaaatttca
     3241 attagggaga tgatgatgct taaaaccttg acttttgccg cactgcattt cagcaccgcc
     3301 ttcagtgtaa cctatgtact gacgggcagt ataggcgtat cgggggcggt cgcgctggtc
     3361 gagcccctaa tcaacaccgt cgttttctat agtggattaa caaaaaccag tacggcgttg
     3421 cctcgcctta gctcaacgag aacgattctc taaggtgctg aagcaccaag tgaatcggtt
     3481 ccgtactatt tgtactgtct gcggcttcgt cgccttgtcc tgattaaaat ttaatccact
     3541 atatttccat gaaaaagcat ggaaccttta cgaaaaaaat aaaacagtca aacaaacaca
     3601 gccgtttcag ctgcaccgga gcagctgacg tttgagcggc atttgacttc gccggacggt
     3661 atgttaccct tgccgtttta accaacaagc aacgaaagga caaatatggg cagcctgatt
     3721 attgaagatt tgcaggaagg cttcggaaaa gaagcagtta aaggcaaaga gattaccgtg
     3781 cattacacag gttggctgga agacggcacc aaattcgccg ccagccgctg accatcacgc
     3841 tcggcgtcgg acaagtcatc aaaggctggg acgaaggctt cggcggaatg aaggagggcg
     3901 gcaaacgcaa gctgaccatc ccttcggaaa tgggctacgg cgcacacggc gccggcggcg
     3961 tgattccccc gcacgccact ttgatatttg aagtcgagct gctgaaagtg tacgaataaa
     4021 gctgcccggg caataccgtc tgacataatg gcttcaagca acgtaaacaa agaaatcaaa
     4081 gacaaaaaac tctccctgtg ggccaagcgt caagacggtt cggtaaaatg gttctgcgga
     4141 cagccggtta cgcgcaacaa agccgccacc gacgacgttg ccgccgccac cgacaacaag
     4201 aagatcgaca ccaagcacct gccgtcaacc tgccgcaatg aatcaactgc cggttgcata
     4261 gaaacaccac ctacggcttt ctataaaaat acctaaaccg tcattcccac gaacctacat
     4321 cccgtcattc ccacgaaagt gggaatccag aacacaaaat ctcaagaaac cgttttcccg
     4381 ataagtttcc gtaccgacag acctagattc ccgcctgcgc gggaatgacg gcggagcggt
     4441 ttctgttgct cccgataaat tcctaaaact caaaatttca tcattccctc aaagacagaa
     4501 aaccaaaata agaaacctaa aattcgtcat tcttttggct gaaggtcaaa aatcagccgt
     4561 caccgagtat tacctgaatc acggcatatg gccaaaaaac aatacttctg ccggcgtggc
     4621 atccaccccc tccgacatca aaggcaaata tgttaaggaa gttacagtcg caaacggcgt
     4681 cattaccgcc acaatgcttt caaccggcgt aaacaaagaa atccaaggca aaaaactctc
     4741 cctgtgggcc aagcgtcaaa acggttcggt aaaatggttc tgcggacagc cggttacgcg
     4801 caacaaagcc gccaccgacg acgacgttac cgccgacggc aacgacaaaa tcgacaccaa
     4861 gcacctgccg tcaacctgcc gcgacgcagc atctgccgtt tgcacaaaaa cacccgagta
     4921 ttacctgaat cacggcaaat ggcctgacgg caacagtaat gccggcgtgg catcttcttc
     4981 aacaatcaaa ggcaaaaaat atgttgagaa agttgaagtc gcaaaaggcg tcattaccgc
     5041 cacaatgctt tcaaccggcg taaacaacga aatcaaaggc aaaaaactct ccctgtgggc
     5101 caagcgtcaa gacggttcgg taaaatggtt ctgcggacag ccggttaagc gcgacgacgc
     5161 caacgccaaa gacgacgttg ccgccgccac cggcaccgac aaaatcgaca ccaaactaaa
     5221 gaaacctttt tacccgataa gtttccgtac cgacagacct ggattcccgc ctgcgcggga
     5281 atgacgaagc tatccttttg gctgaaggtc aaaaatcagc cgtcaccgag tattacctga
     5341 atcacggcga atggccgaaa aacaacactt ctgccggcgt ggcatcctcc gccaccgaca
     5401 tcaaaggcaa atatgttaaa agcgttgaag tcaaaaacgg cgtcgttacc gccgaaatga
     5461 aatcaagcgg cgtaaacaaa gaaatccaag gcaaaaaact ctccctgtgg gccaagcgtc
     5521 aagacggttc ggtaaaatgg ttctgcggac agccggttca gcgcgccagc accgccgcca
     5581 ccgccaacgg cgccgttacc gccgacacca ccggcaccga caagaa
//
LOCUS       DAXIDM010000115         5590 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000115 DAXIDM010000000
VERSION     DAXIDM010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5590
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.115"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(209..3046)
                     /gene="lbpA"
                     /locus_tag="ACFOAE_001774"
                     /gene_synonym="tbpA"
     CDS             complement(209..3046)
                     /gene="lbpA"
                     /locus_tag="ACFOAE_001774"
                     /gene_synonym="tbpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoferrin/transferrin-binding protein LbpA"
                     /protein_id="HFC6885209.1"
                     /translation="MNKKHGFQLTLTALAVATAFPAYAAQAGGATPDAAQTQSLKEVT
                     VRAAKVGRRSKEATGLGKIVKTSETLNKEQVLGIRDLTRYDPGVAVVEQGNGASGGYS
                     IRGVDKNRVAVSVDGVAQIQAFTVQGSLSGYGGRGGSGAINEIEYENISTVEIDKGAG
                     SSDHGSGALGGAVAFRTKEAADLISDGKSWGIQAKTAYGSKNRQFMKSLGAGFSKDGW
                     EGLLIRTERQGRETHPHGDIADGVAYGINRLDAFRQTYGIKKPSEGGEYFLAEGESEL
                     KPVAKVAGNGNYLKNQLNRWVKERIEQNQPLSAEEEAMVREAQARHENLSAQAYTGGG
                     RILPDPMDYRSGSWLAKLGYRFGGRHYVGGVFEDTKQRYDIRDMTEKQYYGTDEAKKF
                     RDKSGVYDGDDFRDGLYFVPNIEEWKGDKKLVRGIGLKYSRTKFIDEHHRRRRMGLLY
                     RYENEAYSDNWADKAVLSFDKQGVATDNNTLKLNCAVYPAVDKSCRASADKPYSYDSS
                     DRFHYREQHNVLNASFEKSLKNKWTKHHLTLGFGYDASKAISRPEQLSHNAARISEHT
                     GEYTVDGKDKYRLGKPEVVEGSVCGYIETLRSRKCVPRKINGSNIHISLNDRFSIGKY
                     FDFSLGGRYDRKNFTTSEELVRSGRYVDRSWNSGIVFKPNRHFSVSYRASSGFRTPSF
                     QELFGIDIYHDYPKGWQRPALKSEKAANREIGLQWKGDFGFLEISSFRNRYTDMIAVA
                     DHKTQLPDSTGRLTEIDIRDYYNAQNMSLQGVNILGKIDWNGVYGKLPEGLYTTLAYN
                     RIKPKSVSNRPGLSLRSYALDAVQPSRYVLGFGYDQPEGKWGANIMLTYSKGKNPDEL
                     AYLAGDQKRYSTKRASSSWSTADVSAYLNLKKRLTLRAAIYNIGNYRYVTWESLRQTA
                     ESTANRHGGDSNYGRYAAPGRNFSLALEMKF"
     gene            complement(3043..5265)
                     /locus_tag="ACFOAE_001775"
     CDS             complement(3043..5265)
                     /locus_tag="ACFOAE_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC6885210.1"
                     /translation="MCKPNYGGIVLLPLLLASCIGGNFGVQPVVESTPTAYPVTFKSK
                     DVPTSPPAGSSVETTPVNRPAVGAAMRLLRRNIATSDKDGNDFPNSKQAEEKLSFKEE
                     DILFLYGSKKDQRQQLEDKIRQPNPTASITTSEKKNKKYDYKFVDAGYVYTKDGKDEI
                     EWTSNYKQSTNRFGYDGFVYYSGEHPSQSLPSAGTVKYSGNWQYMTDAIRHRTGKAGD
                     PSEDLGYIVYYGQNVGATSYAATADDREGKHPAEYTVNFDQKTLNGKLIKNQYVQKRD
                     DPKKPLTIYDITAKLDGNRFTGSAKVNTEVKTNHADKEYLFFHTDADQRLEGGFFGDK
                     GEELAGRFISNDNSVFGVFAGKQKTETANASDTNPALPSGKHTKILDSLKISVDEASG
                     ENPRPFEVSTMPDFGHPDKLLVEGREIPLVNKEQTIDLADGRKMTVRACCDFLTYVKL
                     GRMQTERPAVKPKAQDEEGDEEDAGVDNGEDEEEIAEESEDEVSEDEGEEAEVSEEET
                     EEEAEPQEAEETEEKSPTEESGSGSNAILPTPEAPKGRDIDLFLKGIRTAETDIPQTG
                     KAHYTGTWEARIGEPIQWDNHADKAAKAVFTVDFGEKSISGKLTEQNGVEPAFYIENG
                     KIEGNGFHATARTRDNGINLSGTGSTDPKTFKANDLRVEGGFYGPKAEELGGTIFNKD
                     GKSLDITEDIENKVEAEVEVEAEVETDVSEQLEPLESEVKHQFGVVFGAKKDNKEVEK
                     "
BASE COUNT         1183 a         1489 c         1296 g         1622 t
ORIGIN      
        1 cgtcattccc acgaaagtgg gaatccagct ttttgagttt cagtcattcc cgataaattg
       61 ccttagcatt gaatgtctgg attcccgcct gcgcgggaat gacggcggaa atcttgttta
      121 tatcgaatca aaaaaacctg caccttaatc agttggcggt ttagtccgac ttttggggtg
      181 cagatcaagc tttcagacgg tatttccttt aaaacttcat ttcgagcgcg aggctgaagt
      241 tcctgcccgg tgcggcatac cttccatagt tgctgtcgcc gccgtgccgg tttgccgtgc
      301 tttccgcagt ctggcgcaag gattcccaag taacgtagcg gtagttgccg atattgtaga
      361 tagccgccct caaggtcagc cgttttttca gattcagata agcggaaacg tctgccgtcg
      421 accaagaaga cgacgctctt tttgtcgaat atcgtttttg atcgcctgcc agataagcaa
      481 gctcgtcagg gtttttccct ttggaatagg tcagcataat gtttgcgccc catttcccct
      541 cgggctggtc gtatccgaac cccaaaacat aacgcgacgg ctgtaccgca tccaaagcat
      601 agctgcggag agacaggccc ggtcggttgg ataccgattt cggtttgatg cggttgtacg
      661 ccaatgtggt gtacaaacct tcgggcagtt tgccgtacac accgttccag tcgatttttc
      721 ccaatatatt aacgccttgg agcgacatat tttgggcatt gtaataatcg cgtatatcaa
      781 tctctgtcaa tcgtcctgtt gaatccggca attgggtttt gtgatcggca acggcaatca
      841 tatcggtata gcggttgcgg aagctgctga tttccaaaaa gccgaagtcg cctttccact
      901 gcaaaccgat ttcccggttg gctgcctttt ccgatttcag ggcgggacgc tgccagcctt
      961 tcggataatc gtgataaatg tctatcccga aaagctcttg gaatgagggc gttctgaagc
     1021 cgctggaggc gcggtaagac acggaaaaat gccggttcgg tttgaacacg atgccgctgt
     1081 tccacgaacg gtcaacatac cgtccgctgc ggacgagttc ttccgacgtg gtgaagtttt
     1141 tccggtcata cctgccgccc aagctgaaat cgaaatattt gccgattgaa aaacggtcgt
     1201 tcaaagaaat atggatattg ctgccgttga tttttcttgg cacgcatttg cgggaacgca
     1261 gggtttcgat gtagccgcag accgatcctt cgacgacttc gggcttaccc aaacggtact
     1321 tgtctttgcc gtcgacggtg tactcccccg tgtgttccga aatccttgcc gcattgtggg
     1381 aaagctgttc ggggcgggag atcgctttgg aagcatcgta accgaagccc aaagtcagat
     1441 ggtgtttcgt ccatttgttt ttcagcgatt tctcaaacga ggcattcaaa acattgtgct
     1501 gttcgcggta gtggaaacgg tcgctgctgt cgtaggaata tggtttgtcc gccgacgcgc
     1561 ggcaggattt gtccacagca ggatacacgg cgcaattcag cttcagcgtg ttgttgtcgg
     1621 ttgccacgcc ctgtttgtca aacgacaaca ccgccttatc cgcccaattg tcagaatacg
     1681 cttcgttttc ataacgatac agcaaaccca tacggcggcg gcggtgatgt tcgtcaataa
     1741 atttggtgcg ggaatatttc aaacctatgc ccctgaccaa ctttttatcg cccttccact
     1801 cttctatatt cggcacaaaa tacaagccgt cgcggaaatc gtcgccgtcg tacaccccgc
     1861 tcttgtctct aaactttttc gcctcgtccg taccgtaata ctgtttttcc gtcatatcgc
     1921 ggatatcgta acgctgtttg gtatcctcaa acacgccgcc gacataatgc ctgccgccga
     1981 agcggtagcc cagcttggca agccacgaac cgctgcggta atccatcgga tcgggcaata
     2041 tcctgccgcc gcccgtgtaa gcttgggcgg acaggttttc gtggcgcgcc tgcgcctccc
     2101 gcaccatcgc ttcttcttca gcacttaaag gctgattttg ttcaatacgt tcttttaccc
     2161 agcggttgag ctggtttttc aaatagtttc cgttgcctgc cacttttgcc acaggcttga
     2221 gctcactctc gccctccgcc aggaaatatt cccctccttc acttggtttt ttaatgccgt
     2281 atgtctggcg gaacgcgtcc aaacggttta tgccgtatgc caccccatcc gcaatatcgc
     2341 cgtgcgggtg cgtttcccgc ccctgacgtt cggttcggat tagcagccct tcccaaccgt
     2401 ctttactgaa acccgcgccg agcgacttca taaattggcg gtttttactg ccgtaggcgg
     2461 tttttgcctg tatcccccag cttttgccgt ctgaaatcag gtctgccgcc tctttggtgc
     2521 ggaaagcgac cgcgccgccg agtgcgccgc tgccgtgatc ggacgaaccg gcacctttgt
     2581 cgatttccac cgtgctgatg ttttcatatt cgatttcgtt gattgcgcca ctgccgccgc
     2641 gtccgccgta tccgctcaac gatccctgca cggtaaacgc ctgtatttgg gcaacgccgt
     2701 caaccgaaac cgccacacgg tttttatcca cgccgcgtat cgagtagccg ccgctcgcgc
     2761 cgttgccctg ttcgacaacc gccacgcccg gatcgtagcg cgtcaggtcg cggataccga
     2821 gtacctgttc tttgttcaac gtttccgacg ttttgacgat tttgcccaaa ccggtcgcct
     2881 ctttcgatcg ccgtcccact ttggcggcac ggacggtaac ctctttcagg gattgggtct
     2941 gcgcggcatc aggtgtcgcc ccccccgctt gggcagcata agccggaaaa gcggttgcaa
     3001 cagccaaggc agtcagggta agctgaaaac cgtgtttctt attcattttt ccacctcttt
     3061 attatctttc ttcgcaccga ataccacgcc gaattggtgt ttaacttcag attctaaagg
     3121 ttctaactgt tcgctaacat cagtttcaac ttcagcttca acttcaactt cagcttcaac
     3181 tttattttca atatcttcag ttatatcaag agatttccca tccttattga aaatagtacc
     3241 gcccaattcc tccgccttcg gaccgtaaaa tcctccttct acacgaagat cattagcttt
     3301 gaaggttttg gggtcggtcg aaccagttcc cgaaagattg atgccgttat cccgagtgcg
     3361 cgctgtcgcg tggaaaccgt tgccctcaat cttgccgttt tcaatataga aagcaggttc
     3421 tacgccgttt tgctccgtca gctttccgga aatcgatttc tcgccgaaat caacggtaaa
     3481 tactgctttt gccgctttat ccgcatgatt gtcccattga atgggttcgc cgatacgcgc
     3541 ttcccaagtg ccggtatagt gtgcttttcc ggtttgcgga atatccgttt ctgccgtgcg
     3601 gatacctttc aggaaaaggt cgatgtccct gcctttaggg gcttccggag tgggcaggat
     3661 ggcgtttgaa ccgctgccgc tttcttctgt cggcgatttt tcttcggttt cttcagcttc
     3721 ttggggttca gcttcttctt cggtttcttc ttcggaaact tcggcttctt cgccttcatc
     3781 ttcggaaact tcgtcttcgc tttcttcggc gatttcttct tcgtcttcgc cgttatcaac
     3841 gcctgcatcc tcttcgtccc cctcttcatc ctgcgccttc ggtttgacgg cggggcgttc
     3901 ggtttgcatc cgtccgagtt tcacataggt cagaaaatcg caacaagcac ggacggtcat
     3961 tttcctgccg tcggcaagat cgatggtttg ttctttgttt accaaaggaa tttcacgccc
     4021 ttcgacaaga agtttgtcgg gatgaccaaa atcgggcata gtggaaacct caaacggtcg
     4081 gggattttca ccacttgcct cgtcaacgga aatttttaga gaatccaaga ttttggtgtg
     4141 ttttccagac ggcagggcag gatttgtatc tgatgcgttt gctgtctctg ttttttgttt
     4201 gcctgcgaac acgccgaata cgctgttgtc gttactgata aaccgtccgg caagctcttc
     4261 ccccttatcg ccgaaaaaac cgccctcaag ccgctgatcg gcatcggtat ggaaaaacaa
     4321 atattcttta tcagcgtgat tcgtcttcac ctctgtgtta actttggcac tgccggtaaa
     4381 gcggttgccg tccaattttg cagtaatgtc gtaaatggtc agtggttttt taggatcatc
     4441 tctcttttgc acatactgat ttttaatcag cttgccattc agagtttttt ggtcgaaatt
     4501 aaccgtatat tcggcaggat gttttccctc ccggtcgtcg gcagtcgcag cataagaagt
     4561 tgctccgaca ttttgaccgt aataaacgat ataacccaaa tcttcgctag gatctcctgc
     4621 ttttcctgtt cgatgacgta tggcatcggt catatattgc cagttgccgg aatatttcac
     4681 cgttcccgcg ctcggtaaag attgcgaagg atgttctccg gaataatata caaaaccgtc
     4741 ataaccaaac cggttggtag actgcttgta atttgaagtc cactcaattt catcttttcc
     4801 gtctttagta tatacataac ctgcatctac aaatttataa tcatattttt tatttttctt
     4861 ttccgatgtg gtaatgcttg ccgtaggatt tggttgacga attttatctt caagctgctg
     4921 acgttgatct tttttggaac cgtataaaaa caggatatct tcctctttaa acgacagctt
     4981 ttcttctgct tgtttgctat ttggaaaatc attgccatcc ttatcagaag ttgcaatatt
     5041 ccgtctcaac agccgcattg ccgcaccaac ggcgggtcgg ttgaccggcg tggtttctac
     5101 cgaagacccg gcaggaggcg aagtgggaac gtccttagac ttgaaagtga cggggtacgc
     5161 ggtcggcgtt gattcgacaa caggctgcac gccgaaattg ccgccgatgc aagatgccaa
     5221 aagtaagggc aacaagacaa tgccgccata attcggttta cacatcccta cttttcctcc
     5281 tatttgatta ataataatta tcattatatt aatatgtaca gataatatca acccgttttt
     5341 atagtgaatt aacaaaaatc cggacaaggc gacgagccgc agacagtaca gatacatccc
     5401 gtcattccca cgaacctaca tcccgtcatt cccacgaacc tgcaccacgt cattcccacg
     5461 aaagtgggaa tccagttcgt tcggtttcgc ttgttttaag tttcgggtaa cttctacttc
     5521 gtcattccca cgaaagtggg aatccagttc gttcggtttc gcttgtttta agtttcgggt
     5581 aacttctact
//
LOCUS       DAXIDM010000116         5523 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000116 DAXIDM010000000
VERSION     DAXIDM010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5523
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.116"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..875)
                     /gene="mafA"
                     /locus_tag="ACFOAE_001776"
     CDS             complement(<1..875)
                     /gene="mafA"
                     /locus_tag="ACFOAE_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin MafA"
                     /protein_id="HFC6885211.1"
                     /translation="MQARLLIPILFSVFILSACGTLTGIPSHGGGKRFAVEQELVAAS
                     ARAAVKDMDLQALHGRKVALYIATMGDQGSGSLTGGRYSIDALIRGEYINSPAVRTDY
                     TYPRYETTAETTSGGLTGLTTSLSTLNAPARSRTQSDGSGSRSSLGLNIGGMGDYRNE
                     TLTTNPRDTAFLSHLVQTVFFLRGIDVVSPANADTDVFINIDVFGTIRNRTEMHLYNA
                     ETLKAQTKLEYFAVDRTNKKLLIKPKTNAFEAAYKENYALWMGPYKVSKGIKPTEGLM
                     VDFSDIRPYGNHTGNS"
     gene            complement(1059..1778)
                     /gene="pyrH"
                     /locus_tag="ACFOAE_001777"
     CDS             complement(1059..1778)
                     /gene="pyrH"
                     /locus_tag="ACFOAE_001777"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFC6885212.1"
                     /translation="MTQQIKYKRVLLKLSGESLMGSDPFGINHDTIVQTVGEIAEVVK
                     MGVQVGIVVGGGNIFRGVSAQAGSMDRATADYMGMMATVMNALALKDAFETLGIKARV
                     QSALSMQQIAETYARPKAIQYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEMNCDVML
                     KATNVDGVYTADPKKDSSATRYETITFDEALLKNLKVMDATAFALCRERKLNIVVFGI
                     AKEGSLKRVVTGENEGTLVHC"
     gene            complement(1997..2851)
                     /gene="tsf"
                     /locus_tag="ACFOAE_001778"
     CDS             complement(1997..2851)
                     /gene="tsf"
                     /locus_tag="ACFOAE_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003795802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFC6885213.1"
                     /translation="MAEITAKMVADLRAATGLGMMECKKALVEAEGNFDKAEEILRIK
                     SGAKAGKLAGRTAAEGVLAYAINGNVGALVEVNCETDFVAKDAGFVEFANFVAKTAAE
                     KKPASVEELSELVEAERKAIIAKLGENMSVRRFQVIDTANQLVAYIHGALATEGVLVE
                     YKGSEDVARKIGMHIVAAKPQCVSEAEVDAETVEKERHIYTEQAIASGKPADIAAKMV
                     EGRIRKFLAEITLNGQAFVMNPDQTVAQFAKENGTEVVSFVRYKVGDGIEKAVVDYAA
                     EVAAAAKV"
     gene            complement(2980..3708)
                     /gene="rpsB"
                     /locus_tag="ACFOAE_001779"
     CDS             complement(2980..3708)
                     /gene="rpsB"
                     /locus_tag="ACFOAE_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFC6885214.1"
                     /translation="MSQITMRQMIEAGVHFGHQTRFWNPKMAQYIFGARNKIHIVNLE
                     KTLPMFQDAQEAIRRLVANKGTVLFVGTKRQARDIIREEATRAGMPFVDYRWLGGMLT
                     NYKTVKQSIKRLEEKTAALENAAESGFSKKEILEMQRDVEKLERSLGGIKNMKGLPDA
                     IFVIDTGYQKGTLVEAEKLGIPVIAVVDTNNSPDGVKYVIPGNDDSAKAIRLYCRGIA
                     DAVLEGKNQALQETVAAAQEAAAE"
     gene            complement(3885..4118)
                     /locus_tag="ACFOAE_001780"
     CDS             complement(3885..4118)
                     /locus_tag="ACFOAE_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885215.1"
                     /translation="MWHIVAIGYLFVAVMYSAAQPSIARALIYLVFWAVLPTVFTVFV
                     VTVRRRNRLMKQQEQAEFEQQRAQRQKDSGTKP"
     gene            4196..4777
                     /locus_tag="ACFOAE_001781"
     CDS             4196..4777
                     /locus_tag="ACFOAE_001781"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002243104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFC6885216.1"
                     /translation="MRNEEKRALRRELRGRRSQMGRDVRAAATVKINRLLKRYIKHGR
                     KIGVYWPMGKELRLDGFVRAAQKRGAKLYLPYIEPRSRRMWFTPYPESGMERERIRGR
                     AKLNVPQFAGRKRRVHDLNLLLVPVVGMDRLGYRLGQAGGYYDATLAAMKYRLQAKTV
                     GVGFACQLVGTLPREAHDLPLDGFVSEAGILCF"
     gene            4838..5428
                     /locus_tag="ACFOAE_001782"
     CDS             4838..5428
                     /locus_tag="ACFOAE_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFC6885217.1"
                     /translation="MSEKIILPVLSLGGVRLEPLDVHHETGLREAVCDGEVWKLGVTS
                     APHPDRVADYIGTALATRLAFAVVDEEAGRVVGTTAYYHFEPQIPRLDIGFTWYAASA
                     RRTRINTCCKIMLLDYAFDVLACRCVGWRTDILNLASQRAIERLGAEKDGVLRMHMLR
                     KDGSVRDTVVYSMLREDWCKNREILTGRLAGYGVQV"
BASE COUNT         1240 a         1258 c         1538 g         1487 t
ORIGIN      
        1 gagttacccg tatgattgcc gtatggtcgg atatcggaga aatcgaccat taatccttcc
       61 gtcggtttaa ttcctttgct tactttatac ggccccatcc acaatgcgta attttcttta
      121 taggcagctt caaacgcatt ggttttgggt ttgatgagca attttttatt ggttctgtct
      181 actgcgaaat attccagttt tgtttgggct ttcagtgttt cggcattgta taggtgcatt
      241 tcggttctgt tgcgtatcgt tccgaatacg tcgatgttaa taaacacatc tgtatcggca
      301 ttggcaggag aaacaacgtc tatgccgcgc aggaaaaata cggtctgtac caagtgggaa
      361 agaaaggcag tgtcgcgcgg gttagtcgtc aaggtttcat ttcgataatc ccccatcccg
      421 ccaatattta agcccagact gctcctactt ccgctaccgt ctgattgggt gcgcgagcgt
      481 gcaggggcat taagtgtaga taaagaagtg gttaaacctg tcaaaccgcc tgatgttgtt
      541 tcagcggtgg tttcgtaacg tggataggtg taatcggtac ggacggcagg gctgtttatg
      601 tattcgccac gaatcagtgc atcaatggag tagcgacccc ctgtcaaact gcctgaacct
      661 tggtcgccca tagttgcaat gtacaatgca acttttcgtc cgtgtaatgc ctgtaaatcc
      721 atgtctttaa cggcagctct ggcagaagcg gccacaagtt cttgttcgac cgcaaagcgt
      781 ttacctccgc catgcgatgg aatacctgtc agtgtcccgc aggcggataa aataaaaact
      841 gaaaaaagaa taggtatcag cagccgtgct tgcatagatt ttctcctttg atgaaaaaca
      901 aattgtatca aaattgtaaa tatagtggat taaatttaaa ccagtacggc aaggcgaggc
      961 aacgccgtac tggtttaaat ttaatccact ataatctcca tataataaat ggctgtctga
     1021 agcccatatg cgactatatc tgccgacact atggtcaatc agcagtgaac cagcgtacct
     1081 tcgttttcac cggttactac acgtttgagc gagccttctt tagcaatgcc gaatactaca
     1141 atattgagct tgcgttcgcg gcagagggcg aaagcggtgg catccatcac tttgaggttt
     1201 ttcaacaagg cttcgtcaaa agtaatggtt tcgtagcgcg tggcggatga gtcttttttg
     1261 gggtctgcgg tgtacacgcc gtcaacgttg gtggctttga gcatcacgtc gcagttcatt
     1321 tccgcaccgc gcaatgcggc ggcagtgtcg gtcgtgaaga acgggttacc ggtaccggcg
     1381 gcaaaaatca cgactttgcc ttcttccaaa tattggatgg ctttaggacg ggcgtaagtt
     1441 tcagcgattt gctgcataga cagtgcggat tgtacgcgcg ctttgatgcc taaagtttca
     1501 aatgcgtctt tgagtgccaa cgcgttcatc acggtcgcca tcatgcccat gtagtcggcg
     1561 gtggcgcgat ccatgctgcc tgcttgggcg gatacgcccc ggaaaatatt gccgccgccg
     1621 acaacaatac cgacttgcac gcccatttta acgacttcgg caatttcgcc gacagtttga
     1681 acgatggtat cgtgattgat gccgaacgga tcggaaccca tcagggattc gccggagagt
     1741 ttcagtaata cgcgtttgta tttgatttgc tgtgtcatgg gataccttgc tttcttgaat
     1801 gtcgtcggtc ggagtttggg ccgtctgaat ttcaaacggt cggaatatta atgatagggt
     1861 gtgtcggttt attattgttt tgttttcaga cggcctttat attcggtcgt cttaaaatag
     1921 gtaccgtaaa cggttttctc aaaaaaaagc accctgattc gtttggaatc caggtgcttt
     1981 ctttttcata agtgccttac actttggcgg ctgcggctac ttcggctgcg tagtcgacaa
     2041 cggctttttc gatgccatcg cctactttgt agcgtacgaa gctgaccact tcagtgccgt
     2101 tttctttggc gaattgggca acagtttgat cagggttcat cacgaatgct tggccgttca
     2161 gagtgatttc agccaagaat ttgcggatac ggccttcaac cattttagcg gcgatgtcgg
     2221 caggtttgcc ggaagcgatg gcttgttcgg tgtagatgtg gcgttctttt tcaacggttt
     2281 cagcatctac ttcggcttcg cttacgcatt gtggtttggc ggcaacaatg tgcataccga
     2341 ttttgcgtgc tacgtcttca gagcctttgt actcaaccaa tacgccttcg gtcgccaatg
     2401 cgccgtggat gtaggcaacc agttggttgg cagtgtcgat cacttggaag cgacggacag
     2461 acatgttctc gcccaatttg gcgatgatgg ctttgcgttc tgcttcaacc agttcgctca
     2521 gttcttcaac agaagccggt tttttctcgg cagcagtttt cgcaacgaag ttggcaaatt
     2581 ctacgaagcc cgcgtcttta gcaacgaagt cggtttcgca gtttacttca accaatgcgc
     2641 cgacattgcc gttgattgca taagccaata cgccttcggc agcggtacgg ccggccagtt
     2701 taccggcttt cgcaccggat ttgatacgca ggatttcttc ggctttgtcg aagttgcctt
     2761 cggcttcaac caaggctttt ttgcattcca tcatgcccag gccggtagcg gcgcgcagat
     2821 cggcaaccat ttttgcagta atttctgcca ttttgaatct cctagatttt tgggaaatac
     2881 ggaaaggatt ttccgcattc gggaatcgtg tgccgcgaac ggacgttcag acggcatatt
     2941 tgagaaaagg ggcataacgc ccctcttcgg tttgccagat tactcggcag cggcttcttg
     3001 ggcagcggct acggtttctt gcagcgcttg gtttttgcct tccaaaactg cgtcagcgat
     3061 gccgcggcag tacaggcgga tggctttggc ggagtcgtcg ttgccgggga tgacgtattt
     3121 cacgccgtca gggctgttgt tggtatcgac tacggcgata acggggatgc ccagtttttc
     3181 agcctcgacc agagtacctt tttggtagcc ggtatcgata acgaaaatcg cgtcgggcag
     3241 gcctttcatg tttttgatac cgcccaaaga acgttccagt ttttcaacat cgcgttgcat
     3301 ttccagaatt tcttttttgc tgaaaccgct ttcggcagca ttttccaagg ctgcggtttt
     3361 ttcttccagg cgtttgatgg attgcttaac ggttttgtag ttggtcagca taccgcccaa
     3421 ccagcggtaa tcaacgaaag gcataccggc gcgggtcgct tcttcgcgga tgatgtcgcg
     3481 ggcttggcgt ttggtaccta cgaacaatac tgtacctttg ttggcaacca aacgacgtat
     3541 ggcttcttgc gcgtcttgga acatcggcag ggttttttcc aggttgacga tatggatttt
     3601 gttgcgcgca ccgaaaatgt attgtgccat tttcgggttc cagaaacggg tttggtggcc
     3661 gaagtggaca ccggcttcaa tcatctgacg catagtaatt tgagacattt tgatttcctt
     3721 gaaagggtta agggcacaca ttcaatcgca tagaacttga taggcgacgc ctattgtcaa
     3781 gcacccttcg gcgaaagtgg gcataagttt taaaaaataa aagagtgttt ccgaaatgga
     3841 aaactgacgg attatagcgg ataagaggcc gtctgaaaag ggattcaggg ttttgtgccg
     3901 ctgtcttttt gccgttgtgc acgctgctgt tcgaattctg cctgttcctg ttgcttcatc
     3961 aagcggttgc ggcggcggac ggttacgacg aagaccgtga acacggtggg cagcaccgcc
     4021 caaaaaacca aataaatcaa ggcgcgcgca atactcggct gcgcggcgga atacataacg
     4081 gcaacaaaaa gatagccgat ggcgacgatg tgccacattg tgtgcgtcct gtttgaatgt
     4141 taacaaaatc gttataatcg caacattcta ccgcaatcct gaaaggccgt ctgaaatgag
     4201 gaatgaggaa aaacgcgccc tgcgccgcga attgcgcggg cggcgttcgc aaatggggcg
     4261 ggacgtgcgg gcggcggcaa cggtaaaaat taaccgcctg ctcaaacgtt atatcaagca
     4321 cggtcggaaa atcggcgtgt attggccgat gggcaaggaa ttgcgtttgg acggctttgt
     4381 ccgcgcggcg caaaaacgcg gcgcaaaact ttatctgcct tatatcgaac cgcgttcgcg
     4441 gcggatgtgg tttacgccgt atcctgaaag cggaatggaa cgggagcgca tacggggcag
     4501 ggcgaagttg aacgtgccgc agtttgcagg gcggaaaagg cgtgtgcatg atttgaacct
     4561 cttgcttgtg ccagtggtcg gtatggacag gctgggctac cgtttgggac aggcaggcgg
     4621 ctattacgat gcgacgcttg cggcgatgaa ataccgtttg caggcaaaaa ccgtgggcgt
     4681 gggctttgcc tgccaactgg tcggcacgct gccgcgcgag gcgcacgacc tgccgctgga
     4741 cggttttgtg tcggaggcgg ggatattgtg tttttagccg ttcagacggc attttgaacg
     4801 gaaatgccgt ctgaaggtgg aatattggga gaaaaggatg tcggaaaaga taatactgcc
     4861 ggtcttgtca ttgggcggcg ttcggctcga accgttggat gtgcatcatg aaacgggttt
     4921 gcgcgaggcg gtttgcgatg gggaggtttg gaagctgggg gtaacgtccg cgccccatcc
     4981 ggatagggtg gcagactata tcgggacagc attggcaacg cgtttggcgt ttgcggttgt
     5041 cgatgaagag gcgggcaggg tggtcgggac aacggcgtat tatcattttg aaccgcagat
     5101 tccgcgtttg gatatcggat tcacatggta tgcggcatcg gcacggcgga cacggataaa
     5161 cacctgttgc aaaatcatgc tgttggatta cgcatttgat gttttggctt gccgttgcgt
     5221 gggatggcgc acggatattc tgaaccttgc ctcgcaacgt gccatcgaac ggctgggtgc
     5281 ggaaaaagac ggcgtgctgc gtatgcatat gctccgtaaa gacggcagtg tgcgcgatac
     5341 ggtcgtgtac agtatgctga gggaagattg gtgcaaaaac agggaaatcc tgaccggcag
     5401 gttggcaggg tatggcgtgc aggtgtgagg cagtattttc aaatttatag tggattaaca
     5461 aaaaccagta cggcgttgcc tcgccttagc tcaaagagaa cgattctcta aggtgctgaa
     5521 gca
//
LOCUS       DAXIDM010000117         5410 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000117 DAXIDM010000000
VERSION     DAXIDM010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5410
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.117"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..1063
                     /locus_tag="ACFOAE_001783"
     CDS             <1..1063
                     /locus_tag="ACFOAE_001783"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885218.1"
                     /translation="NMKNKLTLRYFKITRCGYWSGSSKEPNHYEDLLKTLTHLETYVK
                     GKTIEETGISRDDKEPSTFLLDICKKNGLWLLAFWNPAAESSSDEIVSLNMKSKLGQV
                     DSSPVTAGNGKTFGFVSYFLIWPEHNFYSTILSPNATLAGRTEFEEYMLNFLWIDPNF
                     IEKTTYEETSTDGIIHTMERTNFKLPLKINGTPVPRFAGKLAKSPSEKEYVISNYDQV
                     TQVHNQCTVKVTSGQSSSGILKKMLPSFFGSTELFAPLKTIRVNHSVSAAFENKSNLK
                     DWIEDWEKNSFDLDKDDCGFKLKNDDKIYWIRGNVIKCELDVNLHKENGIYPAAKILD
                     IIDQRKDYVLNEFKLSDDS"
     gene            1092..1559
                     /locus_tag="ACFOAE_001784"
     CDS             1092..1559
                     /locus_tag="ACFOAE_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885219.1"
                     /translation="MIGVAWYLGANIRFEEQWVLYEALRTTASIIFAVVGVWLAIVYP
                     ERLKSPFSQTFSSPVYRRGFKQLFSPVISSIFILSIVLLVGLLAPLLKHIEAIIQYIP
                     LCRKISFSLLASLTMWQIYTVLSVLVPLLNILSKNENDCHASNIINKLKGEQN"
     gene            1663..2166
                     /locus_tag="ACFOAE_001785"
     CDS             1663..2166
                     /locus_tag="ACFOAE_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HFC6885220.1"
                     /translation="MSTKFNQFINRVLSHEGGYVNHPKDPGGETNWGITKRTAQANGY
                     NGSMRAMTREQAIGIYRKAFWERYRADQMPEAVAFQFFDACVNHGYGNAVRMLQRAAG
                     VADDGIIGEISLKAINSLPENDLLLRFNAERLVFYTKLSTFTSFGKGWVRRVAQNLIH
                     ASADNTD"
     gene            2278..2610
                     /locus_tag="ACFOAE_001786"
     CDS             2278..2610
                     /locus_tag="ACFOAE_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885221.1"
                     /translation="MLDASPPQERGSRRETRSQKKASQITAFFRWLGGLVSNPATGKI
                     SHTKLWANVAAAAMTWKFVQAADAPEWLWWAYGALVGGYALIKRGIAAIPQLAEIKKS
                     ANQEGGRQ"
     gene            2607..3017
                     /locus_tag="ACFOAE_001787"
     CDS             2607..3017
                     /locus_tag="ACFOAE_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HFC6885222.1"
                     /translation="MIEFVRAKKRLLWAFVLLLVWTCGYRYAADKAEAEQTALIATYR
                     HSSMVAAEQYALQLKKAQDERQRWYDFSQKQGRKPVKKQYPPQTKKAGYLKTKEELLA
                     ELACLTAEMAALKKPDALIHRKEVRQKERNSSQG"
     gene            3022..3570
                     /locus_tag="ACFOAE_001788"
                     /pseudo
     CDS             3022..3570
                     /locus_tag="ACFOAE_001788"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            3586..3771
                     /locus_tag="ACFOAE_001789"
                     /pseudo
     CDS             3586..3771
                     /locus_tag="ACFOAE_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
     gene            complement(4090..4452)
                     /gene="ssrA"
                     /locus_tag="ACFOAE_001790"
     tmRNA           complement(4090..4452)
                     /gene="ssrA"
                     /locus_tag="ACFOAE_001790"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(4515..5120)
                     /locus_tag="ACFOAE_001791"
     CDS             complement(4515..5120)
                     /locus_tag="ACFOAE_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Smr/MutS family protein"
                     /protein_id="HFC6885223.1"
                     /translation="MNTDFQNILKQLGKQAQKEAAEKQAAEKNKQKQEQDFDFSQAVG
                     QVSPLKNRQQYYAPPDKTPIKVRPKDNRADEENYFYIGSTYNDPPASFSKNGQGKNDI
                     QRLKNGYYPVVTDVDLHGYTQEEAQKVLNEFIAFTQKRGVCGEIIHGSGLGSKGYKPV
                     LKNMTRNWLMQHPDVLAYAEPREGNDGCVRILLKRKLRQQD"
BASE COUNT         1472 a         1141 c         1294 g         1503 t
ORIGIN      
        1 gaatatgaaa aataaactga ctttacgtta tttcaaaata actcgttgcg gttattggtc
       61 tggttcttca aaagaaccta atcattatga ggacttatta aaaactttaa ctcatttaga
      121 gacatatgtt aaaggtaaaa ctattgaaga gactggaatt agtcgtgatg ataaagagcc
      181 aagcactttc ttgctcgata tctgcaaaaa aaatggtctg tggttgcttg ctttttggaa
      241 tcctgccgca gaaagctctt cagatgaaat tgtttcttta aacatgaaaa gtaaactagg
      301 tcaagttgat tctagcccag taacagcagg aaatgggaaa acttttggct tcgttagtta
      361 ttttcttatt tggccagaac ataattttta ctcaacgatt ctttctccta atgcaacttt
      421 agctggacga acagagtttg aagagtacat gcttaatttc ttgtggattg atcctaattt
      481 tatagaaaag actacctacg aagaaacttc aacagacgga ataattcata ccatggagcg
      541 aactaatttt aaattgcctc ttaaaattaa tggaactcct gtgccacgtt ttgcggggaa
      601 actagctaaa tctccttcag aaaaagagta tgtcattagt aattatgacc aagtaaccca
      661 agtgcataat caatgcacgg taaaggttac ctctggacaa agttcaagtg gaattttgaa
      721 gaaaatgtta ccaagctttt ttggttcaac agaattgttt gctccattaa aaaccattcg
      781 tgtaaatcat tctgtttctg ctgcatttga aaacaaatca aatcttaagg attggattga
      841 agactgggaa aaaaattctt ttgatttaga taaagatgat tgtggcttta agttaaaaaa
      901 cgatgacaag atttattgga ttcgaggaaa tgtcatcaaa tgtgaattag acgtcaacct
      961 tcataaggaa aatgggattt atccagctgc taaaattcta gatataatag accaaaggaa
     1021 agattacgtt ttaaacgaat tcaaattaag tgatgattct tagaaatatt ttcctaatat
     1081 gctctgcatt catgattggt gtagcctggt atttaggtgc taatatccga tttgaagagc
     1141 aatgggtatt gtatgaagcc ttgagaacaa ctgcatcaat tatttttgca gttgttgggg
     1201 tttggttggc tattgtctat cccgaacgat taaaaagccc ttttagtcaa actttctcct
     1261 ctccggtata tcggcgtgga ttcaaacagc ttttttcccc tgttataagt tccattttta
     1321 ttttaagtat tgtgttactt gttggtttgt tggctccttt gctcaaacat attgaggcaa
     1381 taattcaata tatcccactt tgtcggaaaa tctcatttag cctgttagca agcttgacga
     1441 tgtggcaaat ttatacggtt ttatctgtat tagtgccttt gttaaatatt ttaagtaaaa
     1501 atgaaaatga ctgtcatgca tccaacatta ttaacaagct aaagggtgaa cagaattagc
     1561 tatgtgattt ttagtgtaaa ctgcttttaa ctcgtattaa aaggccactc ttttaatacc
     1621 tcctaaaatc cctgtaccta tcaatagata cagggatttt ttatgtccac caaattcaac
     1681 caattcatca accgcgtcct ctcccacgag ggcggttacg tcaatcatcc caaagacccc
     1741 ggcggcgaaa ccaattgggg catcactaag cgcaccgcac aggcaaacgg ctacaacggc
     1801 tccatgcgcg ccatgacgcg tgaacaggct atcggcattt accgaaaggc gttttgggag
     1861 cgttaccgcg ccgaccaaat gccggaagcg gtcgcgttcc aattttttga tgcctgcgtc
     1921 aaccacggtt acggcaatgc cgtccgtatg ctgcaacgcg ccgcaggcgt ggcggacgat
     1981 ggaatcatcg gcgaaatcag cctcaaagcc atcaattccc tccccgaaaa cgacctttta
     2041 ttgcggttca acgccgagcg tctggtcttt tataccaagc tcagtacgtt cacctctttc
     2101 ggcaagggct gggtacgccg tgtggcgcaa aacctgattc acgcgtctgc agataacact
     2161 gattaaaggg agacaaacca tgtcaaaaaa gtcactcatc gccctaatga ccgcagccat
     2221 gcagcccgat ttcagccaca gcgacctagg cattcgctac gccatgccga ctcagggatg
     2281 ttggacgcaa gcccaccgca agagcggggt agccgccgcg aaacgcgcag ccaaaaaaaa
     2341 gcgtcgcaaa taactgcctt tttccgatgg ctgggcggct tggtctctaa tccggccaca
     2401 ggaaaaatca gccataccaa actttgggca aacgtcgccg cagccgccat gacttggaag
     2461 ttcgtgcagg cggcggacgc gcccgaatgg ctttggtggg catacggcgc attggtcggc
     2521 gggtatgcat taatcaaacg cggcatcgcg gcgattccgc agttggcaga aatcaaaaaa
     2581 tccgcaaatc aggaaggggg gcggcaatga ttgaatttgt ccgagccaaa aaacggctgc
     2641 tttgggcatt tgtgcttttg cttgtgtgga cgtgcggtta ccgatacgcc gccgacaagg
     2701 ccgaagcgga acaaaccgcc ctgattgcca cctatcggca ttcttctatg gttgcggcgg
     2761 aacaatatgc cttgcagctt aaaaaagcgc aggacgaaag gcagcggtgg tacgactttt
     2821 cccaaaaaca aggaagaaag cccgtgaaaa aacagtatcc gccgcaaacg aaaaaagccg
     2881 gctatctgaa aaccaaggaa gaactgcttg cggaattggc ttgccttaca gcggaaatgg
     2941 ctgccctaaa aaagcccgat gccttaatcc ataggaaaga agtgcggcag aaagaacgca
     3001 actcgtcgca gggttaaggc aatgccatcc gttgaactgc tgttggagat tgtcggactg
     3061 ccacgcggca ccttctatta ccaattggcc gtccaatcgg cagaagacaa atatgccgat
     3121 ttgaaacagc atatccatga tatttatcga cgacataagg gaagatacgg ctaccggagg
     3181 attgcagcag ccatccttca tgcaggaaca ccggtcaatc acaagaaagt cagccgtctg
     3241 atggcgaaga cggggctgaa ggcagtgata cggcggcgca aataccgctc gttcaaagga
     3301 gaagtcggca aaattgcgcc gaatatcctg cgacgctgtt tccatgcaga aaagccgaat
     3361 gagaaatggg taacggacgt taccgagttc aatgtaggcg gagaaaagat atacctttct
     3421 ccgattatgg atttgtttaa cggggaaatc gtcagttacc gtattcaaat ccgcccgact
     3481 ttcgatttgg ccggcgagat actgaaaggt gcgccggaga aaccgggatc gtctgaaaag
     3541 ccgatactgc attcggatca aggttggcaa tatcagatgt ttttttatag tggattaaat
     3601 ttaaatcagg acaaggcgat gaagccgcag acagtacaaa tagtacggca aggcgaggca
     3661 acgccgtact ggtttaaatt taatccacta tacaacaacg atagaatcaa gttgaaatta
     3721 aaagggctga gccttgttca gtacagaatt cagtccctga aagccgcttg attaaactgt
     3781 ccgacttttt ggggtcagtt cggcttcggc atttttttat ccgtttgggg gtaacttgtt
     3841 tggaaagctg caagcttata aataaaggat tacatttaag ttttgggtaa cctttttaaa
     3901 aaaatgcgtg atgacttttg catttttaag gcgttttttg gggtaattcg tgaaaagtta
     3961 ccccaaaagt taccccataa atggcgaaaa ctcaagcata cgccagcata ttcaaggcaa
     4021 caaaaaagcc ttgaaactgt tgaagttcaa ggcttttttg tgttgcagga tgctgctgaa
     4081 aatagggtat ggtggaggcg gggggaatcg aacccccgtc cgaaagtcct ctacaaagcg
     4141 ttctacatac ttagttgtgt ctatttgaaa atcttatttc catcatgccg accaacaggc
     4201 cttttggaaa ccagttacct taaatctcat ttcctgccaa gtaacccggt aggaaaccag
     4261 tcaatgtaag atgacgttgc ggtggctttc gccacacagc ccattgaccg actgctgcaa
     4321 cggctagcct taagcggcta aagcgtaagt ttcgtcgttt gcgactattt gaattcagtg
     4381 ttttacggga atctgagacc ccggtatgcc cgcatctgct tcgcaacccc cgtcgaaacc
     4441 aaggtcgccc ccagaaatgg tttgcaaatt atacggatat tgtgcggtgc tgccaagtct
     4501 gtcggagaaa tttgtcagtc ttgctgcctt aatttgcgtt tgagcaggat gcggacgcag
     4561 ccgtcgttgc cttcccgggg ttcggcgtag gcgagtacgt cggggtgttg catcagccag
     4621 tttcgggtca tatttttcag aacgggtttg tagcctttgg aacctaatcc gctgccgtgg
     4681 atgatttcgc cgcatacgcc gcgtttttgg gtgaatgcga tgaattcgtt gaggactttt
     4741 tgggcttctt cctgtgtgta gccgtgcagg tcgacatcgg taacgacggg atagtatccg
     4801 tttttcaggc gttggatgtc gttttttccc tgtccgtttt tgctgaagct ggcgggcggg
     4861 tcgttgtatg tgctgccgat gtagaagtag ttttcttcgt cggcgcggtt gtctttggga
     4921 cggactttga tgggggtttt gtcgggcggc gcataatatt gctgccggtt ttttaatggg
     4981 gagacttgtc cgactgcttg tgaaaaatcg aaatcctgtt cttgtttttg cttgtttttt
     5041 tcggctgcct gtttttctgc cgcttctttt tgggcttgtt tgcccagttg tttgaggatg
     5101 ttttggaagt cggtattcat attttttcct gttatttgtc cgatggctgt ttcgggcggg
     5161 gttttaattt gccggaatgt ttgccaatcg ggggaggatg attttgttgc ctgcgtatgt
     5221 tttttgaaag tgtgattgta tatcaaaaag aaatgcggca accgtcggca gtgttgattg
     5281 ccggaaatgc ggaccggtcg aaccgatatg cccgaacgcc tgataaagtt ttaaaaacct
     5341 gccttgcgaa gcaggctgac gtgttttgcc aatcttgaat tgccggaaac gcgaaacacg
     5401 gaaatctgat
//
LOCUS       DAXIDM010000118         5373 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000118 DAXIDM010000000
VERSION     DAXIDM010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5373
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.118"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..1842
                     /locus_tag="ACFOAE_001792"
     CDS             <1..1842
                     /locus_tag="ACFOAE_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC6885224.1"
                     /translation="YIVDIPKGNLKTEIEKLSKQPEYAYLKQLQVAKNINWNQVQLAY
                     DRWDYKQEGLTEAGAAIVVIIVTALTYGYGAAAAGSVTAAGSSTAAAATTTAAATTTV
                     STAAAMQTAALASLYSQAAVAIINNKGDVGKALKDLGTSDTVKQIVTSALTAGALNQM
                     GADIAQLNSKVRTELFSSTGNQTIANLGGRLATNLSNAGISAGINTAVNGGSLKDNLG
                     NAALGALVNSFQGEAASKIKTTFSDDYVAKQFAHALAGCVSGLVQGKCKDGAIGAAVG
                     EIVAESILGGRNPATLSDAEKHKVISYSKIIAGSVAALNGGDVNTAANAAEVAVVNNA
                     LNFDSTPTNAKKHQPQKPDKTALEKIIQSIMPAHAAGAMTNPQDKDAAIWISNIRNGI
                     TGPIVITSYGVYAAGWTAPLIGTAGKLAISTCMANPSGCTVMVTQAAEAGAGIATGAV
                     TVGNAWEAPVGALSKAKAAKQAIPTQTVKELDGLLQESKNIGAVNTRINIANSTTRYT
                     PMRQTGQPVSAGFEHVLEGHFHRPIANNRSVFTISPNELKVILQSNKVVSSPVSMTPD
                     GQYMRTVDVGKVIGTTSIKEGGQPTTTIKVFTDKSGNLITTYPVKGN"
     gene            1849..2358
                     /locus_tag="ACFOAE_001793"
     CDS             1849..2358
                     /locus_tag="ACFOAE_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885225.1"
                     /translation="MSNFEKKYILELNDALSHLNHNSTSFDLLKVLISWLSNDIVIDK
                     FKILGYDFSKYIEMNPDDYPVEKSILNREEIIYLKNNIYRKISSGNFKFQYFVQYIRD
                     ILEYLFIEHIERVCPYCEWGEMQKLEEQNTHETVYLCTQCGCAFYNDNSQFLLKTPLT
                     IPMKRDEFK"
     gene            2427..4106
                     /locus_tag="ACFOAE_001794"
     CDS             2427..4106
                     /locus_tag="ACFOAE_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC6885226.1"
                     /translation="MIYGSMPSEKLTIFQTAFVMQVNIQIPCMLYRRGSVKPPLFEAP
                     RLLPSFTDPVVPKLSAPGGYIVDIPKGNLKTEIEKLAKQPEYAYLKQLQVAKNVNWNQ
                     VQLAYDKWDYKQEGLTRAGAAIIALAVTVVTAGAGVGAALGLNGAAAAAADAAFASLA
                     SQASVSLINNKGDVGKTLKELGRSRTVKNLVVAAATAGVSNKLGASSLATWSETPWVN
                     NLNVNLANAGSAALINTAVNGGSLKDNLEANILAALVNTAHGEAASKIKQLDQHYIAH
                     KVAHAVAGCAAATANKGKCQDGAIGAAVGEIVGEALVKNTDFSDMTPEQLDLEVKKIT
                     AYAKLAAGTVAGVTGGDVNTAAQTAQNAVENNAVKAVVTAAKVVYKVARKGLKNGKIN
                     VRDLKQTLKDEGYNLADNLTTLFDETLDWNDAKAVIDIVVGTELNRANKGEAAQKVKE
                     VLEKNRPYIPNKGAVPNMSTYMKNNPFGKQLAQISEKTTLPTQQGQSVFLVKRNQGLL
                     KTGDRFYLDGQHKNHLEVFDKNGNFKFVLNMDGSLNQMKTGAAKGRKLNLK"
     gene            4115..4492
                     /locus_tag="ACFOAE_001795"
     CDS             4115..4492
                     /locus_tag="ACFOAE_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885227.1"
                     /translation="METLNDIKKILINVGLYQGFDLTDPKVSEEVNHETANMKWIKDY
                     TSDGNWDNEFKEDLKNFLDYMEVCQLALNDKNFKIASNSLFMAMIYAGNLSLIFDSIK
                     TDISTLLSAEYKKNSFSWPSLDE"
     gene            4770..5144
                     /locus_tag="ACFOAE_001796"
     CDS             4770..5144
                     /locus_tag="ACFOAE_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885228.1"
                     /translation="MKNFNVVKESLRELGIKQGFDLYEKATTEKLNSEDPLDLQWLSN
                     YSSDWNDELEEDFDSFFQHMKEYQYAIDNEDIKSACSSLCEAMLYVGNIKNFFEFLKS
                     DMIRLLRGESKTTDFQWPQFDE"
BASE COUNT         1718 a         1069 c         1226 g         1360 t
ORIGIN      
        1 tatatcgtcg acattccgaa aggcaatctg aaaaccgaaa tcgaaaagct gtccaaacag
       61 cccgagtatg cctatctgaa acagctccaa gtagcgaaaa acatcaactg gaatcaggtg
      121 cagcttgctt acgacagatg ggactacaaa caggagggct taaccgaagc aggtgcggcg
      181 attgtggtga ttattgtaac cgctctaact tatggatacg gagcggctgc agcgggtagc
      241 gtaactgccg caggaagtag tacagccgca gctgcaacaa cgacagcggc agcaactacc
      301 actgtttcta ctgcagctgc catgcaaacc gcagctttag cctccttgta tagccaagca
      361 gctgtagcca tcatcaataa taaaggcgat gtaggcaaag cattaaaaga tctcggcacc
      421 agtgatacgg tcaagcagat tgttacttcc gcactgacgg cgggtgcatt aaaccagatg
      481 ggagcagata ttgcccaatt gaacagcaag gtaagaaccg aactgttcag cagtacgggc
      541 aatcaaacca ttgccaacct tggaggcaga ttggccacca acctcagcaa tgcaggtatc
      601 tcagctggta tcaataccgc cgttaacggc ggcagcttga aagacaactt aggcaatgcc
      661 gcattgggag cattggttaa tagcttccaa ggggaagccg ccagcaaaat caaaacaacc
      721 ttcagcgacg attatgttgc caaacagttc gcccacgctt tggcgggttg tgttagcgga
      781 ctggtacagg gaaaatgtaa agatggggca attggcgcag cagttgggga aatcgtagct
      841 gaatccatac ttggcggcag aaaccctgct acactcagcg atgcagaaaa gcataaagtt
      901 atcagttact cgaagattat tgcgggcagc gtggcggcac ttaacggcgg cgatgtgaat
      961 actgcggcga atgcggctga ggtagctgtg gtgaataatg ctttgaattt tgacagcacc
     1021 cctaccaatg cgaaaaagca tcaaccgcag aagcccgaca aaaccgcact ggaaaaaatc
     1081 atccaaagta ttatgcctgc acatgcggca ggtgcgatga ctaatccgca ggataaggat
     1141 gctgccattt ggataagcaa tatccgtaat ggcatcacag gcccgattgt gattaccagc
     1201 tatggggttt atgctgcagg ttggacagct ccgctgatcg gtacagcggg taaattagct
     1261 atcagcacct gcatggctaa tccttctggt tgtactgtca tggtcactca ggctgccgaa
     1321 gcgggcgcgg gaatcgccac gggtgcggta acggtaggca acgcttggga agcgcctgtg
     1381 ggggcgttgt cgaaagcgaa ggcggccaag caggctatac caacccagac agttaaagaa
     1441 cttgatggct tactacaaga atcaaaaaat ataggtgctg taaatacacg aattaatata
     1501 gcgaatagta ctactcgata tacaccaatg agacaaacgg gacaaccggt atctgctggc
     1561 tttgagcatg ttcttgaggg gcacttccat aggcctattg cgaataaccg ttcagttttt
     1621 accatctccc caaatgaatt gaaggttata cttcaaagta ataaagtagt ttcttctccc
     1681 gtatcgatga ctcctgatgg ccaatatatg cggactgtcg atgtaggaaa agttattggt
     1741 actacttcta ttaaagaagg tggacaaccc acaactacaa ttaaagtatt tacagataag
     1801 tcaggaaatt tgattactac atacccagta aaaggaaact aactaaatat gagtaacttt
     1861 gaaaaaaaat atattttaga attaaatgat gctttaagcc atttaaatca taactctacc
     1921 tcatttgatt tattgaaagt tttgatttca tggttatcaa acgatattgt cattgataaa
     1981 tttaaaattt taggttatga ctttagtaaa tatatcgaaa tgaatcccga tgactatccg
     2041 gttgaaaaat ctatattgaa tagagaggaa attatttatc tcaaaaacaa tatttatcgt
     2101 aaaatatcat caggaaattt taaatttcaa tactttgtac aatatattag agatatttta
     2161 gaatatttat ttattgaaca tattgaaaga gtctgtcctt actgcgaatg gggtgaaatg
     2221 caaaaattag aagaacaaaa tacgcatgaa acggtgtatc tctgtactca atgtggatgt
     2281 gctttttata acgataattc acaattttta ttaaaaaccc ctttaaccat tccaatgaaa
     2341 cgtgatgaat ttaaataaac aagccgtagc ctgcatgaac cctaaaattc acgtgtagcg
     2401 tgtgtgcgcc agcacgcatg cgttccatga tttacggctc aatgccgtct gaaaagctca
     2461 caatttttca gacggcattt gttatgcaag taaatattca gattccctgt atgctgtaca
     2521 gacgcgggag tgttaagccc cccttgtttg aagctccgcg gctcctgccg agcttcaccg
     2581 accccgttgt gcccaagctc tctgctcccg gcggctacat tgtcgacatc cccaaaggca
     2641 atctgaaaac cgaaatcgaa aagctggcca aacagcccga gtatgcctat ctgaaacagc
     2701 tccaagtagc gaaaaacgtc aactggaacc aggtgcaact ggcttacgat aaatgggact
     2761 ataagcagga aggcttaacc agagccggtg cagcgattat cgcgctggct gttaccgtgg
     2821 ttactgcggg cgcgggagtc ggagccgcac taggcttaaa cggcgcagcc gcagcagcgg
     2881 ccgatgccgc ctttgcctca ctcgcttctc aggcttccgt atcgctcatc aacaataaag
     2941 gcgatgtcgg caaaaccctg aaggaactgg gcagaagccg cacggtaaaa aatctggttg
     3001 tagcggcggc aacggcaggc gtatccaaca aactcggtgc ctcttccctt gccacttgga
     3061 gcgaaacccc ttgggtaaac aacctcaacg ttaacctggc caatgcgggc agtgccgcgc
     3121 tgatcaacac cgctgttaac ggcggcagcc tgaaagacaa tctggaggca aatatcctgg
     3181 cggcattggt gaataccgcg catggggagg ctgcgagtaa gattaagcaa ttggatcagc
     3241 actatatcgc ccacaaagtt gcccatgccg tagcaggctg tgcagcagcg acggcgaata
     3301 agggtaagtg tcaggacggt gcgattggcg cagccgtggg tgagattgtt ggggaagctt
     3361 tggttaaaaa taccgatttt agcgatatga ccccggaaca attagatctg gaagttaaga
     3421 aaattaccgc ctatgccaaa cttgcggcag gtacagttgc aggcgtaacg ggaggagatg
     3481 tcaatactgc tgcacaaacc gcacaaaacg cggtagaaaa taatgcggtt aaagctgttg
     3541 taactgctgc aaaagtggtt tataaggtag ccagaaaagg attaaaaaac gggaaaatca
     3601 acgttagaga tttaaaacag acgttgaaag acgaaggtta taatttagcc gacaacctga
     3661 ccaccttatt cgacgaaaca ttggattgga acgatgccaa agccgttatt gatattgtcg
     3721 tcggaacaga gctgaatcgc gctaataaag gggaagcggc acaaaaggtc aaggaagttt
     3781 tagaaaaaaa tcgtccttat atccctaata aaggtgctgt accgaatatg agtacataca
     3841 tgaaaaataa tccttttgga aaacagctgg ctcaaatttc agaaaagaca acgcttccga
     3901 cgcagcaagg gcagtctgtc ttcttggtaa aaagaaacca agggttatta aaaaccggtg
     3961 ataggtttta tttagatggc caacataaaa atcatttaga ggtttttgat aaaaatggga
     4021 actttaagtt tgttctaaat atggatggtt cgcttaacca aatgaaaact ggggcagcaa
     4081 aaggtcgtaa attaaactta aaataggaaa ttttatggaa acattgaatg atataaaaaa
     4141 aatcttgatt aatgtggggc tttatcaagg gtttgatttg acagatccaa aagtatcaga
     4201 agaagttaat catgaaacag ctaatatgaa atggattaaa gattatactt cagacgggaa
     4261 ttgggataat gaatttaagg aggatttaaa aaacttttta gattatatgg aagtatgcca
     4321 attagcccta aacgataaaa atttcaaaat tgccagtaat tctttattta tggctatgat
     4381 ttacgcaggt aatctatctc ttatatttga ttcaataaaa actgatatat caacattatt
     4441 gagtgctgag tataaaaaga atagtttttc atggccatct cttgatgaat agaaagcaag
     4501 ttgtagcctg catgaaatct aaaacccatg cataaggtgt gggcttcagt atacgcgttc
     4561 catgatttac ggccatatgc cgtctgaaaa gctcaatttt ttcagacggc atttgttatg
     4621 aaagtaaata tttagattcc ctgtatactg tttagactcg tgtgtgctga gtaagctgta
     4681 gtctgcatga aacctaaaac tcgctcaaaa ttaagctaag acattagcag ggcaagggcg
     4741 aaaattgaat cttaaataag gtgattcaga tgaaaaattt taatgtagta aaagaaagtt
     4801 taagagagtt aggaattaaa caaggatttg atctttatga gaaagccaca actgaaaaat
     4861 tgaatagtga agatcctctt gacttacaat ggctttctaa ctattcatct gattggaatg
     4921 atgaattaga agaagacttt gattcttttt ttcagcatat gaaggaatat caatatgcta
     4981 ttgacaatga agacattaaa tctgcatgta gttcactatg tgaagctatg ctctatgttg
     5041 gtaatattaa aaattttttt gagtttctca aaagcgatat gattagactg ttgagaggtg
     5101 aaagtaaaac aacagacttt caatggccgc aatttgatga atagcagcaa gctgtagcct
     5161 gcatgaaacc taaaatccat gcgtaaggtg tgtgcttcag cacgcacgcg ttccatgatt
     5221 tacggctcaa tgccgtctga aaagctcaca atttttcaga cggcatttgt tatgcaagta
     5281 aatattcaga ttccctatat actgcccaga tgcgtgcgtg ctgaagacac cccctacgct
     5341 tgctatttga aacagctcca agtcaccaaa gac
//
LOCUS       DAXIDM010000119         5266 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000119 DAXIDM010000000
VERSION     DAXIDM010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5266
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.119"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..339
                     /locus_tag="ACFOAE_001797"
                     /pseudo
     CDS             1..339
                     /locus_tag="ACFOAE_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003698053.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(360..1586)
                     /locus_tag="ACFOAE_001798"
     CDS             complement(360..1586)
                     /locus_tag="ACFOAE_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003699499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY family inner membrane protein"
                     /protein_id="HFC6885229.1"
                     /translation="MTFLQRLQGLADNKICAFAWFVVRRFDEERVPQAAASMTFTTLL
                     ALVPVLTVMVAVASIFPVFDRWSDSFVSFVNQTIVPQGADMVFDYINAFREQANRLTA
                     IGSVMLVVTSLMLIRTIDNTFNRIWRVNSQRPWMMQFLVYWALLTFGPLSLGVGISFM
                     VGSVQDAALASGAPQWSGALRTAATLTFMTLLLWGLYRFVPNRFVPARQAFVGALATA
                     FCLETARSLFTWYMGNFDGYRSIYGAFAAVPFFLLWLNLLWTLVLGGAVLTSSLSYWQ
                     GEAFRRGFDSRGRFDDVLKILLLLDAAQKEGKALPVQEFRRHINMGYDELGELLEKLA
                     RHGYIYSGRQGWVLKTGADSIELNELFKLFVYRPLPVERDHVNQAVDAVMTPCLQTLN
                     MTLAEFDAQAKKQQQS"
     gene            complement(1601..2026)
                     /locus_tag="ACFOAE_001799"
     CDS             complement(1601..2026)
                     /locus_tag="ACFOAE_001799"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885230.1"
                     /translation="MPSEHAAYADLMASSAKRLLCAKAILFSSAVRTGAAVGNIFFDG
                     FADGGDFGDGAQYGFATFNAVDAASDSAGGIAGAAVLEIVEDEDFEGDLGSWADSVKM
                     VRSSDGITVVPMPSETAAVQAFVPDGKIGYNIGHQCPTY"
     gene            2131..2790
                     /gene="queC"
                     /locus_tag="ACFOAE_001800"
     CDS             2131..2790
                     /gene="queC"
                     /locus_tag="ACFOAE_001800"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HFC6885231.1"
                     /translation="MSNQKALVIFSGGQDSTTCLIQAIQIYGRENVQAITFQYGQRHA
                     VELERARWIAQDLGVKQTVLDLSLMRQITHNALMDDTAAIETAENGVPNTFVDGRNAL
                     FLLYAAIYAKGQGIRHIIAGVCETDFSGYPDCRDVFVKSMNVTLNLAMDYDFQIHTPL
                     MYLTKAQTWALADEMGVLDYIREQTHTCYNGIVGGCRECPSCILRERGLAEYLESKKA
                     V"
     gene            2818..3333
                     /locus_tag="ACFOAE_001801"
     CDS             2818..3333
                     /locus_tag="ACFOAE_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003698058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1543 domain-containing protein"
                     /protein_id="HFC6885232.1"
                     /translation="MPKLHMFYLGGNAGRSNIEVHDIQFAVCDDYREAVPALKAAWFG
                     DADKIHIDGWQVVEWADGYDIAVSETPKTEMPSEHAPRLYFANVGGYRAGQLAEAHAF
                     GLFAAATPAEAKQKALQTLLTDHVQQHKDNLKDVDNLLALDRIGNFHIRLTPNPHGKP
                     AEIGFQGYLPI"
     gene            3340..3762
                     /gene="queD"
                     /locus_tag="ACFOAE_001802"
     CDS             3340..3762
                     /gene="queD"
                     /locus_tag="ACFOAE_001802"
                     /EC_number="4.1.2.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HFC6885233.1"
                     /translation="MKITKIFTFDSSHMLDGHDGKCQNLHGHTYKLEITVSDDPVRGG
                     PKDGMVMDFTDLKAIVKQHITDPFDHAFIYHGGNGRESQIAALLEGWNMKTLRLPCRT
                     TAENMAVEMYDRLKNAGLNVCRVKLWETPTSCAEYEGE"
     gene            4031..4402
                     /locus_tag="ACFOAE_001803"
     CDS             4031..4402
                     /locus_tag="ACFOAE_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017629259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFC6885234.1"
                     /translation="MKLLFILLVLFVAVEHFYIAWLEMTQIPSEKAAEIFKLPYEFME
                     QKQVQTLFSNQGLYNGFLGIGLVWSRFAAPDNAVYGATTLFLGFVLIAAAWGAFSSGN
                     KGILVKQGLPAMLAAAAVLAV"
     gene            4399..5037
                     /locus_tag="ACFOAE_001804"
     CDS             4399..5037
                     /locus_tag="ACFOAE_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003777273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HFC6885235.1"
                     /translation="MKKINVAPENPQYRIVEIFESLQGEGWNTGMPAVFVRLGKCNLA
                     CGWCDTDYLTFGMMGLSDILGRLKTYAARNIIITGGEPTIQPHLDMLLDTLKAEGYFL
                     CLETNGLNPAPPQIDYVATSPKACYAAKYENSCIETADEVRIVADGDVLAFCENMERK
                     IRAHHYYLSPCEQDGAMNIYDTIRQIGILNSRPDAPVHWQLSVQTHKWAGIE"
BASE COUNT         1344 a         1520 c         1322 g         1080 t
ORIGIN      
        1 gttttttcga tacggaaccg gatagaggaa aaatcgaaca ttgcgcctgc cttgctatga
       61 ttcacgaaga aatctccgcc atgcctatgg gctatgaaac cttgatcggc gatatgggca
      121 gcgcactgtc aggcggacaa aaacaacgca tcgtattggc gcgggcctta atattgcgaa
      181 ccgaaaatcc tatttttaga tgcagcgacc agccatttgg atattgccaa tgaaaaagca
      241 gtcaatgcaa acttgaatgg cttgtctatc ataaaaatta tggcggcaca cagaaaggaa
      301 acggtggaat cagcagatag gaaaatgtct ttaggataaa aatacagttt caaaaatact
      361 caagattgct gctgtttttt cgcctgagcg tcaaactctg ccagcgtcat gttcaaagtc
      421 tgcaaacacg gtgtcattac cgcatcgaca gcttggttca catgatccct ttccacaggc
      481 aacggacggt aaacgaagag cttgaagagt tcgttcaact caatcgaatc cgcccccgtt
      541 ttcaacaccc aaccctgtct gccggaatag atgtagccgt gccgcgccag cttttccaaa
      601 agctcgccca actcgtcgta gcccatattg atatgccgtc tgaactcctg aacaggcaag
      661 gctttgcctt ctttttgcgc cgcatccaga agcagcagga ttttcaacac gtcgtcaaac
      721 cgtccgcgcg agtcgaagcc cctgcggaac gcttctccct gccagtagga gagtgaagaa
      781 gtcagcaccg cgccgcccaa gaccagcgtc cacaacaggt tcagccacaa cagaaaaaac
      841 ggcacggcgg caaacgcgcc gtaaatcgag cggtagccgt cgaaattgcc catataccaa
      901 gtgaagaggg agcgcgcggt ttccagacaa aacgctgttg ccaaagcccc gacaaacgcc
      961 tgccgcgcgg gaacgaagcg gtttggcacg aagcggtaca gcccccacag caaaagcgtc
     1021 atgaaggtca gcgtcgccgc cgttcgcaac gcgcccgacc actgcggcgc acctgaggca
     1081 agcgcggcat cctgtaccga gccgaccata aaggaaatgc ccacgcccaa agacagcggc
     1141 ccgaacgtca gtaaagccca atagacgaga aactgcatca tccacggacg ctgggaattg
     1201 acccgccaga tgcggttgaa cgtattgtct atcgtccgaa tcagcatcag cgaggtaacg
     1261 accagcatca cgctgccgat tgccgtcagc cggttcgcct gctcgcggaa cgcattgata
     1321 tagtcgaaca ccatgtccgc gccctgcggc acaatggttt ggttgacgaa ggagacgaac
     1381 gaatccgacc agcggtcgaa cacggggaaa atcgaagcga ccgccaccat cacggtcagc
     1441 acggggacga gtgccagcag cgtcgtaaac gtcatgcttg ccgccgcctg cggtacgcgt
     1501 tcttcatcaa agcggcggac gacgaaccat gcaaacgcac agattttatt gtctgccaaa
     1561 ccttgcaaac gttgtaaaaa ggtcataatt tcttgcccgg tcagtaagtt gggcattgat
     1621 gcccgatgtt atagccaatt ttgccgtcag gaacaaatgc ctgaactgcg gctgtttcag
     1681 acggcatcgg aacaactgtt atgccgtctg aagaccgaac cattttaacg gaatccgccc
     1741 atgaacccaa atccccctca aaatcctcgt cctctactat ttccaaaacg gcagcacccg
     1801 caatcccgcc cgccgaatcg ctcgcggcat cgacagcgtt gaaggttgcg aagccgtatt
     1861 gcgcaccgtc cccaaagtct ccgccgtctg cgaagccgtc aaaaaagata ttcccgacag
     1921 cggctcccgt cctgaccgcc gaagaaaaca atatcgcctt cgcacaaagt aaacgcttgg
     1981 cggaactcgc catcaagtcg gcataagccg cgtgttcaga cggcatggcg ttcagatgcc
     2041 gtctgaacgc gtttgcctgt ataatccgcg tctttactgt ccaacttcgc ggttcgaaaa
     2101 cctcccgcgt caccaaaact aggattcgat atgtcaaacc aaaaagcctt ggtcatcttt
     2161 tcgggcggtc aggattcgac cacctgcctg attcaggcaa tccaaatcta cgggcgcgaa
     2221 aacgtccaag ccattacttt ccaatacggg caacgccatg ccgtcgagct ggaacgtgcc
     2281 cgctggattg cgcaggattt gggcgtcaaa caaaccgtac tcgacttgag cctgatgcgg
     2341 cagattacgc acaatgccct gatggacgac accgccgcca tcgaaactgc cgaaaacggc
     2401 gttccgaata cctttgtaga cggccgcaac gcgcttttcc tgctctatgc cgcgatttac
     2461 gccaaagggc aggggatacg gcacatcatc gcgggcgtgt gcgaaaccga cttctccggc
     2521 tatcctgact gccgcgacgt gttcgtcaaa tccatgaacg ttacccttaa tttggcgatg
     2581 gactatgatt tccaaatcca cacgccgctg atgtatctga ccaaggcgca aacgtgggcg
     2641 ttggcggacg aaatgggcgt gctggactat atccgcgagc aaacccacac ctgctataac
     2701 ggcatcgtcg gcggctgccg cgaatgcccg agctgtatct tgcgcgaacg cgggctggcg
     2761 gaatatctgg aaagtaaaaa ggccgtctga acacgcgcaa accataagga atacgatatg
     2821 cccaagctcc atatgtttta cctcggcggc aatgccggca ggtcgaatat cgaagtgcac
     2881 gacatccaat ttgccgtgtg cgacgactac cgtgaagccg tccccgcact caaagccgcg
     2941 tggttcggcg atgcggacaa aatccacatc gacggctggc aggttgtcga atgggcggac
     3001 ggttacgaca tcgccgtatc cgaaacgccc aaaacggaaa tgccgtctga acacgccccg
     3061 cgcctgtatt ttgccaatgt cggcggttat cgcgcggggc agcttgccga ggcgcacgcg
     3121 ttcgggctgt tcgccgccgc cacgcctgcc gaagccaaac aaaaagccct gcaaaccctg
     3181 ttgaccgacc atgttcagca acataaagac aacttaaaag acgtggacaa cctgcttgcg
     3241 ctcgaccgca tcggcaattt ccatatccgc ctgaccccga atccgcacgg caaacccgcc
     3301 gaaatcggct ttcaaggcta tttgcccatt tgagaaccca tgaaaatcac caaaatcttc
     3361 accttcgact cctcgcatat gctcgacggg catgacggca aatgccaaaa cctgcacggg
     3421 catacctaca aactcgaaat caccgtttca gacgaccccg tcagaggcgg gccgaaagac
     3481 ggtatggtga tggactttac cgacttgaaa gccattgtca aacaacacat taccgacccc
     3541 ttcgaccacg ccttcatcta ccacggcggc aacgggcgcg aatctcaaat cgccgcactc
     3601 ttggaaggct ggaacatgaa aaccctgcgc ctgccctgcc gcaccactgc cgaaaatatg
     3661 gcggtcgaaa tgtacgaccg tctgaaaaac gcggggctga acgtgtgccg cgtcaaattg
     3721 tgggaaacgc cgacatcgtg tgcggagtat gaaggggagt agggaatatc ttgaacgtat
     3781 cgatatagta aattccaata agacatgccc aaccgcgtca ttcccgcgca ggcgggaatc
     3841 cagaccttga tttatcagga atatttaaaa attgcagcaa ttccaactct ctggattccc
     3901 gcctgcgcgg aaaggacggt ttagagcgtc cttatttgaa tttaccgtaa aacggttttt
     3961 tctcctgtac ggattccccg ttttttcaga cgaccttcca tatcaaatac acccattaaa
     4021 aggaataccc atgaaactcc tcttcatcct cctagtcctc ttcgtcgccg tcgaacattt
     4081 ctacatcgcc tggcttgaaa tgacacagat tcccagcgaa aaagcggcgg aaatattcaa
     4141 gctgccttat gaatttatgg aacaaaagca agtgcagacc ttgttcagta atcaagggct
     4201 gtataacggc tttctcggca tcgggctggt gtggtcgcgg tttgccgcgc cggacaacgc
     4261 cgtttacggc gcgacgactc tgtttctcgg tttcgtattg attgccgccg cgtggggcgc
     4321 gttttcgtcc ggcaacaaag gcatactcgt caaacaagga ctgcccgcga tgctggcggc
     4381 ggcagcggtg ttggcggtat gaaaaaaatc aatgttgccc ccgaaaatcc gcaataccgt
     4441 atcgtcgaaa ttttcgagag cctgcaaggc gaaggctgga acacgggcat gcccgccgtt
     4501 ttcgtccgct tgggcaaatg caatctggcg tgcggctggt gtgataccga ttatttgaca
     4561 ttcggtatga tgggcttgtc cgatatctta ggccgtctga aaacctacgc cgcccgcaac
     4621 atcatcatca ccggcggcga gccgaccata cagccgcatc tcgatatgct gctggacacg
     4681 ctcaaggcgg aaggctattt cctctgtctc gaaaccaacg gactcaatcc cgcgccgccg
     4741 caaatcgact acgtcgccac cagccccaaa gcctgctacg ccgccaaata tgaaaatagc
     4801 tgtatcgaaa cagccgacga agtgcggatt gttgccgatg gtgatgtcct tgcgttctgc
     4861 gaaaacatgg aacgcaaaat ccgcgcacat cattactacc tttcgccctg tgagcaagac
     4921 ggtgcgatga acatctacga caccatccgc caaatcggta ttttaaacag tcgccccgac
     4981 gcgccggtgc attggcagtt gagcgtgcag acgcacaaat gggcgggaat agagtagttt
     5041 aagcagtgta actcaaaggg ccggcgtacc gttttgccga tgtctaacat atgggaaaag
     5101 tgtgccgctt ccgcgtgaaa ctgcccacat ttccgctgcc tgattgaggc ggaaccttac
     5161 tgaataagat gccgccgttg ggtacaagcc cggcttccta aattccgatg gtcttttgaa
     5221 ccttgccgat actctgtgcc agtgcgcgca aatggcaggg ttaggg
//
LOCUS       DAXIDM010000120         5165 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000120 DAXIDM010000000
VERSION     DAXIDM010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5165
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.120"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(672..2948)
                     /gene="znuD"
                     /locus_tag="ACFOAE_001805"
                     /gene_synonym="tdfJ"
     CDS             complement(672..2948)
                     /gene="znuD"
                     /locus_tag="ACFOAE_001805"
                     /gene_synonym="tdfJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_118820519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent zinc receptor ZnuD"
                     /protein_id="HFC6885236.1"
                     /translation="MAQTTLKPIVLSILLINTPLLAQAHETEQSVDLETVSVVGKSRP
                     RATSGLLHTSTASDKIISGDTLRQKAVNLGDALDGVPGIHASQYGGGASAPVIRGQTG
                     RRIKVLNHHGETGDMADFSPDHAIMVDSALSQQVEILRGPVTLLYSSGNVAGLVDVAD
                     GKIPEKMPENGVSGELGLRLSSGNLEKLTSGGINIGLGKNFVLHTEGLYRKSGDYAVP
                     RYRNLKRLPDSHADSQTGSIGLSWVGEKGFIGAAYSDRRDQYGLPAHSHEYDDCHADI
                     IWQKSLINKRYLQLYPHLLTEEDIDYDNPGLSCGFHDDDDAHAHAHNGKPWIDLRNKR
                     YELRAEWKQPFPGFEALRVHLNRNDYHHDEKAGDAVENFFNNQTQNARIELRHQPIGR
                     LKGSWGVQYLGQKSSALSAIPETVKQPMLIDNNVRHYSFFGVEQANWDNFTLEGGVRV
                     EKQKASIQYDKALIDRENYYNQPLPDLGAHRQTARSFALSGNWYFTPQHKLSLTASHQ
                     ERLPSTQELYAHGKHVATNTFEVGNKHLNKERSNNIELALGYEGDRWQYNLALYRNRF
                     GNYIYAQTLNDGRGPKSIEDDSEMKLVRYNQSGADFYGAEGEIYFKPTPRYRIGVSGD
                     YVQGRLKNLPSLPGREDAYGNRPFIAQDDQNAPRVPAARLGIHLKASLTDRIDANLDY
                     YRVFAQNKLARYETRTPGHHMLNLGANYRRNTRYGEWNWYVKADNLLNQSVYAHSSFL
                     SDTPQMGRSFTGGVNVKF"
     gene            3370..3960
                     /locus_tag="ACFOAE_001806"
     CDS             3370..3960
                     /locus_tag="ACFOAE_001806"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HFC6885237.1"
                     /translation="MLLFIDNYDSFTYNIVQYFTELGQEVAVRRNDDITLEEIEALNP
                     QYLVIGPGPCSPKEAGISVAAMRHFAGRLPIMGVCLGHQTIGEAFGGRIVRAKTLMHG
                     KVSPVSHSGKGMFKGLPNPVTCTRYHSLVIDRNTMPECLEVTAWTEDGEIMGVRHKEY
                     AVEGVQFHPEALLTEHGHDMLNNFLVEFQNFKPQKI"
     gene            4024..5082
                     /gene="trpD"
                     /locus_tag="ACFOAE_001807"
     CDS             4024..5082
                     /gene="trpD"
                     /locus_tag="ACFOAE_001807"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HFC6885238.1"
                     /translation="MITPQQAIERLISNNELFYDEMTDLMRQMMSGKVPPEQIAAILT
                     GLRIKVETVSEITAAAAVMREFATKVPLENAEGLVDIVGTGGDGAKTFNISTTSMFVA
                     AAAGAKVAKHGGRSVSSSSGAADVVEQMGANLNLTPEQVAQSIRQTGIGFMFAPNHHS
                     AMRHVAPVRRSLGFRSIFNILGPLTNPAGAPNQLLGVFHTDLCGILSRVLQQLGSKHV
                     LVVCGEGGLDEITLTGKTRVAELKDGKISEYDIRPEDFGIETRRNLDEIKVANTQESL
                     LKMNEVLEGREGAARDIVLLNTAAALYAGNVAASLSDGISAAREAIDSGRAKSKKEEF
                     VGFQPQQRCHFLGKMELG"
BASE COUNT         1199 a         1192 c         1466 g         1308 t
ORIGIN      
        1 gaattggatt cccgcctgcg cgggaatgac gacttattag ttacctaaaa cttaaaaaac
       61 agaaaccttt acgccgtcat tcccacgaaa gtgggaatct aaaacccaaa tgctaaggcg
      121 atttatcgga aacggctgaa accgaacgaa ttggattccc gcctgcgcgg gaatgacgac
      181 ttattagtta cctaaaactt aaaaaacaga aacctttccg catcattccc acgaaagtgg
      241 gaatctggga acttaacgtt acagtgattt atcggaaacg gctgaaaccg aacgaattgg
      301 attcccgcct gcgtgggaat gacaactcat tagttaccta aaacttaaaa aacagaaacc
      361 tttacgccgt cattcccacg aaagtgggaa tctagaaccc aaatgctaag gcgatttatc
      421 ggaaacgact gaaaccgaat gaattggatt cccgcctgcg tgggaatgat gggatcttgg
      481 gtttttgctt ttgatttttc tgcttttgcg agaatgacgg cgtgaaagca agaatgatga
      541 aacaaaaaaa atgggaatga tggcatagtg gtttgttctt tgtctttgcc atatttccta
      601 acaaattgat taaaaagaaa aaaggttttc agaatgccgt ctgaaaacct tttttgtttg
      661 cctgtccgat tttaaaactt cacgttcacg ccgccggtaa agctgcggcc catttgcggc
      721 gtatcagaga ggaagctgct gtgggcgtaa acggattggt tgagcaggtt gtcggctttg
      781 acgtaccaat tccactcgcc atagcgcgta ttgcggcggt agtttgcgcc gaggttgagc
      841 atatggtgtc cgggcgtgcg cgtttcgtag cgggcgagtt tgttttgggc gaacacgcgg
      901 tagtagtcca aattggcatc gatacggtcg gtcagcgagg ctttcaggtg gatgccgagg
      961 cgcgcagccg gaacgcgagg cgcgttttgg tcgtcctgtg caatgaaagg acggttgccg
     1021 taagcatctt ccctgccggg tagggatggc aggtttttca gacggccttg tacatagtcg
     1081 ccggaaacgc cgatgcggta gcgcggtgtg ggcttgaagt agatttcgcc ttctgcaccg
     1141 tagaagtccg caccggattg gttgtagcgc acgagcttca tttcgctgtc gtcttcgatg
     1201 gatttggggc cgcgtccgtc gtttaaggtt tgggcgtaaa tgtagttgcc gaaacggttg
     1261 cggtagagtg ccagattgta ttgccagcgg tcgccttcgt agcccagcgc gagttcgatg
     1321 ttgttggaac gctctttatt gaggtgtttg ttgccgactt caaaagtgtt ggtggcgacg
     1381 tgcttgccgt gtgcgtacag ctcttgcgtt gacggcaggc gttcctgatg ggaggcggtc
     1441 agactgagtt tgtgttgtgg cgtgaaatac cagttgcccg aaagtgcgaa cgagcgggcg
     1501 gtttggcggt gcgcgccgag gtcgggcagg ggttggttgt agtagttttc ccgatcaatc
     1561 aatgctttgt cgtactggat ggaggctttt tgtttttcca cgcgtacgcc gccttcaagc
     1621 gtgaagttgt cccagtttgc ctgttctaca ccgaaaaagc tgtaatggcg tacattgttg
     1681 tcaatcaaca tcggttgttt gacggtttcg ggaatggcgg aaagcgcgct ggatttttgt
     1741 cccaaatatt gcacgcccca gctgcctttc agacggccta tgggttggtg gcgcaactcg
     1801 atacgggcgt tttgcgtttg gttgttaaaa aagttttcga ctgcatcgcc tgctttttcg
     1861 tcgtggtggt agtcgttgcg gttcaggtgt acgcgcaggg cttcaaaacc ggggaatggc
     1921 tgcttccatt cggcgcggag ttcgtagcgt ttgttgcgca ggtctatcca aggtttgccg
     1981 ttgtgggcat gggcgtgtgc atcatcgtcg tcgtgaaagc cgcagctcaa gcccggattg
     2041 tcgtaatcga tgtcttcttc ggtcaacagg tgcggataaa gctgcaaata gcgtttgtta
     2101 atcaaactct tttgccagat gatgtcggcg tggcaatcat cgtattcgtg gctgtgggca
     2161 ggcagaccat attggtcgcg acggtcgctg tatgctgcgc cgataaagcc tttttcgcca
     2221 acccaagaca gcccgatgct gcccgtttgc gaatcggcgt ggctgtcggg caggcgtttc
     2281 agattgcggt aacgcggtac ggcgtaatcg cccgatttgc ggtacaagcc ttccgtgtgc
     2341 aatacaaagt ttttgcccaa accgatattg atgccgccgg acgtgagttt ttccagattg
     2401 ccgctgctca aacgcaatcc gagttcgccc gatacgccgt tttcaggcat tttttcgggg
     2461 attttgccat cggcaacatc gaccagcccc gccacattgc ccgagctgta caagagcgta
     2521 accggaccgc gcaggatttc gacctgttgc gacaaggcgc tgtccaccat gattgcatgg
     2581 tctggagaga agtccgccat gtcgcccgtt tcgccgtgat ggttcaacac tttaatccgc
     2641 ctgcctgttt gaccgcgaat gacgggagca gacgcgccgc cgccgtattg cgaagcgtgg
     2701 atgcccggta cgccgtctaa agcgtcgccc aagttgacgg ctttttggcg caaggtatcg
     2761 ccggagatga ttttgtcgga ggcggtcgaa gtgtgcaaca gccccgacgt ggcgcgcgga
     2821 cggcttttgc cgacgacgct gaccgtttcc aaatccaccg attgctcagt ttcatgcgct
     2881 tgggcgagga ggggtgtgtt gattaaaaga attgataaaa caatgggttt gagtgtagtt
     2941 tgtgccattt tggcttctcg tcgcatttca aaagtttgtt attatataac attgcattcc
     3001 ttatatcata agattttgag aacactcaga gggcataggc aaaagttttt caaatgaaac
     3061 ggttgcggca tcgggcggtg tccatttgta tccgccgtcc ttcgggggcg cggttgatgt
     3121 tgacgcagat tccgctgtgt ttgcccatta tgttcggctg cgggataacc aaaatttatg
     3181 agtgcataaa aacggcacgt tcccgaacgg tcgaaaaggt ggcaaaatgg cgtacttgtc
     3241 agaacgcgag gctctgcgcc aggttcacga gggcgcatcg ggcacgctaa gatataagag
     3301 ggtatggatg ggggtatcgg aaatgcagtt aataacaaac aaattataaa tcaataggtt
     3361 aatcacaaaa tgcttttgtt tatcgacaat tacgacagtt ttacttacaa catcgtccag
     3421 tatttcactg aattggggca ggaagttgcc gtgcgccgca acgatgatat tacgttggag
     3481 gaaatcgagg cattgaatcc gcaatatctc gttatcggcc ccggcccgtg ttcgcccaaa
     3541 gaagcgggga tttccgtggc ggcgatgcgc catttcgccg gccggctgcc gattatgggc
     3601 gtgtgcctcg ggcatcagac gataggcgag gcgttcggcg gcaggatagt ccgcgccaaa
     3661 acgctgatgc acggtaaggt gtcgcccgtg tcccattcgg gcaagggtat gtttaagggt
     3721 ttgcccaatc cggttacctg tactcgttat cacagcctcg ttatcgatcg gaatacgatg
     3781 cccgaatgtt tggaagtaac ggcttggact gaggacggcg agattatggg tgtgcgccat
     3841 aaggaatatg ccgtcgaggg cgtgcagttc caccccgaag ctctgctgac cgaacacgga
     3901 catgatatgt taaacaattt tttagttgaa tttcaaaact tcaaaccgca aaaaatctga
     3961 cgtgatgccg tctgaatccc ttcagacggc attttcgtcc gaatattgaa cggaggacaa
     4021 aaaatgatta caccgcaaca ggctatcgaa cgattaatca gcaataatga gttgttttac
     4081 gatgaaatga ccgacttgat gcgccaaatg atgagcggaa aagtgccgcc cgaacaaatt
     4141 gcggcgattt tgacaggatt gcgtatcaag gttgaaaccg tttccgaaat taccgcagct
     4201 gcagccgtca tgcgtgagtt tgcgacaaaa gtgccgctgg agaatgcaga ggggctggtc
     4261 gatatcgtcg gtacgggcgg ggatggcgcg aaaaccttca atatttcgac gacttcgatg
     4321 tttgttgccg cagcggcagg cgcgaaggtt gccaaacacg gaggccggtc ggtctcttcc
     4381 tccagcggtg cggctgacgt ggtggagcag atgggcgcaa acctcaacct gactcccgaa
     4441 caggttgccc aaagtatcag gcagaccggc atcgggttta tgttcgcgcc caatcaccac
     4501 agtgccatgc gccatgtcgc ccctgtacgc cgttcgctcg gtttccgaag tattttcaac
     4561 atattgggtc cgttaacgaa tcctgcgggc gcgccgaacc agcttttggg cgtgttccac
     4621 accgatttgt gtggcatttt gtcgcgggtc ttgcaacaac ttggttcaaa acacgttttg
     4681 gttgtttgcg gggagggcgg tttggatgaa attacactga cgggcaaaac acgcgttgcc
     4741 gagctcaaag acggaaaaat cagcgaatac gacatccgcc cagaagattt cggtatcgaa
     4801 acccgccgca atttggatga aatcaaagtt gccaatactc aggaatcttt gttgaaaatg
     4861 aatgaggtgc tggaaggaag agaaggggct gcgcgcgata tcgtattgct caacaccgcc
     4921 gccgccctgt atgccggaaa tgtcgctgct tcgctttcag acggcatatc tgccgcacgg
     4981 gaagccatcg attcaggcag ggccaaatcg aaaaaagagg agtttgtcgg ttttcaacca
     5041 caacaaagat gccattttct tggaaagatg gagcttgggt gatgccgcca tgattatgga
     5101 acttttgtgg caaaacataa gcacttcacg aagagaactt accaaactgt ttttatataa
     5161 aaact
//
LOCUS       DAXIDM010000121         5040 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000121 DAXIDM010000000
VERSION     DAXIDM010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5040
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.121"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            376..780
                     /locus_tag="ACFOAE_001808"
     CDS             376..780
                     /locus_tag="ACFOAE_001808"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFC6885239.1"
                     /translation="MTAQPCPICTAQDEDILLQTPKLRVIAVHNDSGSPAFCRVIWRK
                     HIAEMTDLSAAERGELMEMVYKVEAAMRQVFRPAKINLASLGNVVPHLHWHIIARFEN
                     DASFPAPIWANPVRKHGMTLPQDWTEQLKKLL"
     gene            820..2004
                     /locus_tag="ACFOAE_001809"
     CDS             820..2004
                     /locus_tag="ACFOAE_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HFC6885240.1"
                     /translation="MTEPTSRRRFLKTCTAAAGAGLLQACGTSATSVPPLPSSHSVVK
                     ARTVPLQTPRRQSSDGNLLRVVASSGFAEDTNRVNTALTRLYNVGFTVTNQQAGSRRF
                     QRFAGTDTQRAADFQEVASGRVATPKVLMGLRGGYGAARILPHIDFASLGARMREHGT
                     LFFGFSDVCAVQLALLAKGNMMSFAGPMAYSDFGKPAPGAFTMDAFIKGATQNRLTVD
                     VPYIQRADVETEGILWGGNLSVLASLASTPYMPDIDGGILFLEDVGEQPYRIERMLNT
                     LYLSGILKKQRAIVFGNFRMEKIRDVYDPSYDFSAVANHVSRTAKIPVLTGFPFGHIA
                     DKITFPLGAHARIRMNGNSGYSVAFEGYPTLDASALTLDTLLPPPDLPIFPESGVADI
                     SE"
     gene            complement(2067..2600)
                     /locus_tag="ACFOAE_001810"
     CDS             complement(2067..2600)
                     /locus_tag="ACFOAE_001810"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFC6885241.1"
                     /translation="MGIYDFQMKDAEGNAVDLSGYRGKVLLIVNTATRCGLTPQYEAL
                     QKLYAQYTAEGLEILDFPCNQFREQAPESSGEIAQVCMMKFGTKFKIFDKIEVNGANT
                     APLYAYLKSVKPQDKGNHLFKDFVLKLAALGEKRDEGDIKWNFTKFLVNRDGEVVERF
                     APSVTPEEIEADIRALL"
     gene            complement(2779..5034)
                     /locus_tag="ACFOAE_001811"
                     /pseudo
     CDS             complement(2779..5034)
                     /locus_tag="ACFOAE_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582176.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nitric-oxide reductase large subunit"
BASE COUNT         1286 a         1394 c         1255 g         1105 t
ORIGIN      
        1 gggaatctaa aaacccaacg ctgcaagatt tatcagaaac aactgaaacc gaacggactg
       61 gattcccgcc tgcgcgggaa tgacgggatt ttagtaaccg tagcaaccgc ctgcgcgacg
      121 gctaaggggc ttcagcaacc gtagcaactg cctgtgtggg aatgacggac aatgggcttc
      181 agacggcatc tcttgcctgc cgctaaaaca gtttgccgca caactgttca aacgcgtccg
      241 atatgtttca acacacagga cgacacataa agcaccgccc tatgaagtgg tacaattaac
      301 ggcaatgcgg acagacagat tgaaatatta aaaattgccc taccgttttt taaacacttt
      361 caggaataag gaaaaatgac cgcccaaccc tgccccatct gcacggcaca agatgaagat
      421 attttgctgc aaacccccaa gctgcgcgtc atcgccgtcc ataacgatag cggttcgcct
      481 gcattctgcc gcgtcatttg gcgtaagcat attgccgaaa tgaccgacct ttcggcagcg
      541 gaacgcggcg aattgatgga aatggtgtac aaagtcgaag ccgctatgcg ccaagtgttc
      601 cggccggcaa aaatcaacct cgccagcttg ggcaatgtcg tgccgcacct gcattggcat
      661 attatcgccc gctttgaaaa cgatgcgtct ttccccgcgc cgatttgggc aaaccccgtc
      721 cggaaacacg gtatgaccct gccgcaagat tggacggaac agcttaaaaa gctgctttaa
      781 gcccgccaat gccgtctgaa accgtatgaa agggaaatta tgaccgaacc gacctcccgc
      841 cgccgttttc tgaaaacctg caccgccgct gccggcgcgg ggctgcttca ggcttgcggc
      901 acatccgcca catccgttcc gccccttccc tcttcccatt ccgttgtgaa agcccgaacc
      961 gtgcctctcc aaacgccacg ccgtcaaagt tcggacggca accttctgcg cgttgtcgct
     1021 tcgtcaggat ttgccgaaga caccaaccgc gtcaacacag ccttaacccg cctttacaat
     1081 gtcggtttta ccgtaaccaa ccaacaggcg ggcagccgcc gtttccaacg gtttgccggc
     1141 acggacacgc aacgtgccgc cgatttccaa gaggtcgctt ccggccgcgt cgccacgcct
     1201 aaagtgctga tgggcttgcg cggcggttac ggtgcggcgc ggattctgcc gcatatcgat
     1261 tttgcttcgc tcggcgcaag gatgcgcgaa cacggcacgc tctttttcgg attcagcgac
     1321 gtatgcgccg tccagctggc attgttggca aaaggcaata tgatgagttt tgccggcccg
     1381 atggcttata gcgattttgg caaacccgcc cccggtgcgt ttacgatgga tgcctttatc
     1441 aagggtgcaa cccaaaaccg cctgaccgtt gatgttcctt atatccaacg cgccgatgtc
     1501 gaaaccgaag gcatattgtg gggcggcaac ttaagcgtcc tcgcctcgct cgccagcacg
     1561 ccttatatgc ccgacatcga cggcggcatt ttgttcctcg aagatgtcgg cgaacagccc
     1621 taccgcatcg aacgtatgct caatacgctg tatctttcgg gtattttgaa gaaacagcgc
     1681 gccatcgtgt tcggcaattt ccgtatggaa aaaattcgag atgtctatga tccgtcttat
     1741 gatttttctg ccgttgccaa ccatgtttcg cgcacggcga aaatccccgt gctgacgggc
     1801 ttcccgttcg gacacattgc cgacaaaatc actttccctc taggcgcgca cgcccgaatc
     1861 cgtatgaacg gaaacagcgg ttattcggtc gcgtttgaag gctacccgac actcgatgcg
     1921 tccgccctga ctttggatac cctgctccca ccgccggatt tgcccatctt ccccgaaagc
     1981 ggtgttgccg atatttcgga ataaacccgc aaacggacaa atgccgtctg aagccttcag
     2041 acggcatttc ccaagacggc ggcagattac agcaatgccc gaatatcggc ttcgatttct
     2101 tcgggcgtaa cactaggcgc aaaacgctcg accacttcgc cgtcgcggtt gacgagaaat
     2161 ttggtaaagt tccatttgat gtcgccttcg tcgcgcttct ctcccaaagc tgcgagcttc
     2221 aacacgaaat ctttaaacag atgattgcct ttatcttgcg gtttgacgga tttcaggtag
     2281 gcatacaagg gcgcggtatt tgctccattg acttcgattt tgtcgaaaat cttaaacttc
     2341 gtgccaaact tcatcataca cacttgggca atttctccgc tgctttcggg agcctgttcg
     2401 cggaactggt tgcacggaaa atccaaaatc tccaagcctt ctgcggtata ttgtgcatac
     2461 agcttctgca aagcctcgta ttgcggggtc agaccgcaac gcgttgccgt gttgacaatc
     2521 agcagaacct tgccgcgata gcctgacaaa tcaaccgcat tgccttccgc atctttcatt
     2581 tgaaaatcgt aaatacccat ttttatcctt atctgatgta aaccgatgcc atctgaaacg
     2641 tgcttcagac ggcatgaaag cagcaattgt atagccgatt aaaataaaaa atccacatcc
     2701 ttttccattc ccgtcccaat ccgcaataaa aaactgcacc cgaaaacggg tgcagttgct
     2761 catttcatac cgcaaaactt atttgtcgcg gccgaatacg attttagtgg cttggatggc
     2821 aacgcagatt gcaccgccga taaagaccaa gtcagctgcc gtacgtaccc aacgcaaggt
     2881 atcgaggatt tccatttgca ggaactcttc gctgcgtgca taccacaaac cgtgagtaat
     2941 agaggcatat gcttgaatag caccgacagg cagcaggctg ataacaatca tgccgaccaa
     3001 accgccgttg agcagccaga agccccaagt catcagtttg tcgtcaaact gcgcgttcgg
     3061 tttcaaataa cgggcaacca gcaatacgaa gcccaatgcc aagaaaccgt acacaccgaa
     3121 caaggcggcg tgcgcatgaa cagcagaagt attcaaacct tggatataga acagggaaat
     3181 cggcgggtta atcaggaaac cgaatacacc ggcaccgatc atattccaaa aggcgactgc
     3241 cacgaagcac atcagcggcc aacgcaggcg tttcgcccag tcggacaggt gttggtaaga
     3301 ccagtgttcg tatgcttcac ggcccagcaa caccagcggc acgacttcca aagcggagaa
     3361 gcaggcaccg attgccatag aggcggaggt agagccggag aagtacaggt ggtgcagcgt
     3421 acccggaacg ccgcccaaca taaagatggc ggcagcggcc agagtagaag ctgtggcggt
     3481 actgcggcgg acaaagccca tattgtagaa gacaaaggca aaagcggcag tggcaaatac
     3541 ttcaaagaag ccttccaccc acaggtgaac cacccaccaa cgccagtatt ccattacggc
     3601 aatcggggat ttttcgccat agaacaggcc tggtgcgtag aatacgccca caccgaccat
     3661 agaagcgaca aagattgcca gcaggttttt gtccacgcct ttttctttaa aggcggagat
     3721 ggtgcaacgc agcatcagga acagccacaa cagcagaccg accatcagca ggagttgcca
     3781 gaaacgtccc aaatcgaggt attcgtaacc ttggtgtccg aaccagaaat tcaattcggg
     3841 gggaaggatg tgcgtcaacg cgaagaagtt gcccgcgtaa gaaccgccga ccacgatgaa
     3901 gagggcgata tagaggaagt tcacgcctgc acgttggaac ttgagatctt tgccgccgtt
     3961 gacaatcggc gcgaggaaca aacctgccgt caaaaagccg gttgcaatcc agaagatggc
     4021 ggattggatg tgccaagtac gggtcagggc atagggaaac cagtcggaca tttcaaagcc
     4081 caacgcctca tcgatgccgt agaaaccctg accttcgacg gtgtagtgcg cggtcaggcc
     4141 gcccagcaat acttgtacca caaacagggc gaccgtcagg aagacgtatt tgcccaatgc
     4201 tttttgcgaa ggggtcagtt ggattttgga aatcgtgtct tcagacggca cttccacttc
     4261 ctcgtgtttg gtcaggaagg aataacccca catcaacaaa ccgatgccca tcaagagcag
     4321 tacgacactg gtaaacgacc acatatagtt ttcagtggtc ggcacattgt tgatcaaagg
     4381 ctcgtgcggt cagttgttgg tataggtaaa cgtctcgtca ggacggttgg tcgaagcaga
     4441 ccaagaagtc cagaagaaaa agtcgaacag tttttcacgc gcttcttggc ttggcaatgt
     4501 gttgtttttc attgcaaagt gttcgcgggt ggtttgcaac ttgggatcgt cgccgtaaac
     4561 gccgtgataa taaggcagga tgctttcgat ggcttttaca cgcgtatcgc tgatgaccac
     4621 agaaccatct tctttcacac ggctttgatt acggtattcg tcagccaagc gtgttttcaa
     4681 gacagcttgt tcttcagggg aaacttcatc gaattttttg ccgtaagtct gttgcgcggt
     4741 caaatccaac caggcggaca actcacgatg cagccagtcg gccgtccagt ccggagcttg
     4801 gtatgcaccg tgacccaata cagagccgac ttccataccg ccggtagtct gccatgcaga
     4861 ttgacctgcc aaaatatcgt ctttggccat caggactttg ccggatgcag aaacgacttg
     4921 ttcagggtaa ggcggggctt ttttgtaaac ctcgctgccc atatagccaa gaatggtaaa
     4981 gcataccgcc agaacggcaa acagcaagta ccacagcttc ttgtactgtc ccattttgag
//
LOCUS       DAXIDM010000122         5026 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000122 DAXIDM010000000
VERSION     DAXIDM010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 5026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5026
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.122"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..876
                     /locus_tag="ACFOAE_001812"
     CDS             <1..876
                     /locus_tag="ACFOAE_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HFC6885242.1"
                     /translation="GNTIYPQFSTQVEKGVLFAKGALLRTGIVLYGFRLTFGDIADVG
                     LNAVVTDAIMLISTFFFTVLLGIRYLKMDKQLVYLTGAGCSICGAAAVMAAESVTKAE
                     SHKASVAIAIVVIFGTLAIFTYPLFYTWSQDLINAHQFGIYVGSSVHEVAQVYAIGEN
                     IDPIVANTAVISKMIRVMMLAPFLLMLSWLLTRSNGVSENTSHKITIPWFAVLFIGVA
                     IFNSFDLLPKELVKLFVEIDSFLLISSMAALGLTTQASAIKKAGLKPFVLGILTYLWL
                     VVGGFLVNYGISKLI"
     gene            902..1321
                     /locus_tag="ACFOAE_001813"
     CDS             902..1321
                     /locus_tag="ACFOAE_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2251 domain-containing protein"
                     /protein_id="HFC6885243.1"
                     /translation="MAQLPLYLTSEIKDFTVGTPEVLQSFFEHVPYGVVFEDDGDTGY
                     FYAASQDGILDALHIYNVEDVSDKHIPNHVLILWDDACTIAALCINDYIHAVYDFVEQ
                     AGYCRNGFPEAGGEWVKVENRILDDELLDKILSRKST"
     gene            1343..1849
                     /gene="luxS"
                     /locus_tag="ACFOAE_001814"
     CDS             1343..1849
                     /gene="luxS"
                     /locus_tag="ACFOAE_001814"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFC6885244.1"
                     /translation="MPLLDSFKVDHTRMHAPAVRVAKTMATPKGDTITVFDLRFCVPN
                     KEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPSEQQVAD
                     AWLASMQDVGNVKDQSKIPELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELT
                     LDEGLLNA"
     gene            1995..4790
                     /gene="polA"
                     /locus_tag="ACFOAE_001815"
     CDS             1995..4790
                     /gene="polA"
                     /locus_tag="ACFOAE_001815"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFC6885245.1"
                     /translation="MSNRPTLLLVDGSSYLYRAYHAMGQNLTAPDGAPTGALYGVLNM
                     LRRLRSEYPHDYCAVVFDAKGKNFRHQMFEEYKATRPPMPDDLRPQAEALPDLVRLTG
                     WPVLVIGQVEADDVIGTLAKQGAEHGLRVIVSTGDKDMAQLVDERVTLVNTMSSETLD
                     IEGVKAKFGVRPDQIRDYLALMGDKVDNVPGVEKCGPKTAVKWLEAYGSLAGVMEHAS
                     EIKGKVGENLQAALPQLPLSYDLVTIKTDVDLHAELSDGIESLRRTTPKWAQLVVDFK
                     RWGFRTWLKEAESNMNTGSTDDLFGSDSIGEQAALNAEMPFEKQAEKATAPEKLDYQA
                     VTTEAQFAALLDKLSRADTIGIDTETTSLDAMNASLVGISIAFQAGEAVYIPVGHSLT
                     AAPEQLDLQDVLGRLKPHLENPALKKIGQNLKYDQHVFANYGIALNGIAGDAMLASYI
                     IESHLGHGLDELSERWLGLETITYESLCGKGAKQISFADVAIGQATEYAAQDADFALR
                     LEAHLRAQMDAKQLEMYEKMELPVAQVLFEMERNGVQIDRAELARQSAELGAELMKLE
                     QEAYAAAGQPFNLNSPKQLQEILFDKMGIPTKGLKKTAKGGISTNEAVLEQLAPDYPL
                     PKIILQNRSLAKLKSTYTDKLPEMISPKDGRVHTTYAQAVAITGRLASNNPNLQNIPI
                     RTAEGRRVRRAFTAPQGSVIVSADYSQIELRIMAHLSGDKTLIAAFQNGEDVHRRTAA
                     EVFGTAPENVSPEQRRYAKTINFGLIYGMGQYGLAKSLGIDNLSAKNFIDRYFARYPG
                     VAEYMQRTKEQAAAQGFVETLFGRRLYLPDIRNKNANARAGAERAAINAPMQGTASDL
                     IKRAMIDVSRWLVSDDLKSKLIMQVHDELVLEVVETELDFVKEKLPQIMAKVGGGLLD
                     VPLVAEVGVGENWEEAH"
BASE COUNT         1287 a         1344 c         1254 g         1141 t
ORIGIN      
        1 ggcaatacca tttatccgca attttcaaca caagtggaaa aaggcgtttt gtttgccaaa
       61 ggcgcgcttc ttcgcactgg cattgtgctg tatggtttcc gcctcacttt tggcgatatt
      121 gccgatgtag gattaaatgc tgtcgtcact gatgcaatca tgctaatttc aaccttcttt
      181 tttaccgtac ttttaggcat tcgttatcta aaaatggata aacaattggt ttatctcact
      241 ggggcaggtt gcagcatttg cggtgcggca gcagtgatgg cggcagagtc tgttaccaaa
      301 gcagaatccc ataaagcttc agtggcgatt gccatagtgg tcattttcgg gacgcttgct
      361 atttttactt accccttgtt ctacacgtgg tcacaagatt taattaacgc ccatcaattc
      421 ggtatttatg ttggttctag tgtacacgaa gtggctcaag tttatgcgat tggggaaaat
      481 attgatccta tcgtggcgaa tactgccgtc atttccaaaa tgatccgagt gatgatgctc
      541 gccccctttt tattaatgct ttcttggtta ttaacacgta gtaatggagt atcagaaaat
      601 acatcacaca aaattacaat tccttggttt gctgtacttt ttattggtgt tgccattttt
      661 aattcttttg atttattacc aaaagaactc gtgaaattat tcgttgaaat cgattctttc
      721 ttattaattt catcaatggc tgcgcttggc ttaacgacgc aagcaagcgc aatcaaaaag
      781 gcaggattaa aaccgtttgt tttaggaata ctaacttatt tatggctagt ggttggtgga
      841 tttttagtga actatggaat atcaaaatta atataaaatt cactaaagag agcgttaccc
      901 aatggcacaa ttaccgctat atctgacttc tgaaatcaaa gactttactg tcggcacgcc
      961 cgaagtttta caatcatttt tcgaacatgt cccttatggt gtcgtctttg aagacgacgg
     1021 cgacacaggc tacttctatg ccgcttcgca agacgggatt ttagatgcct tgcacatcta
     1081 caatgtcgaa gatgtatccg acaaacatat ccccaatcat gtcttgattt tatgggatga
     1141 tgcctgcacc atagccgcat tgtgtatcaa cgactacatt catgccgtct atgattttgt
     1201 cgaacaggca ggatattgcc gcaacggctt ccctgaagca ggcggcgaat gggtgaaagt
     1261 cgaaaaccgc atcttggacg atgaattgct ggacaaaatc ctatcccgaa aatctacata
     1321 acctactcaa aaggataaca aaatgcccct gttagacagt ttcaaagtcg atcacacccg
     1381 tatgcatgcc cccgccgtac gcgtggcgaa aaccatggcc acgcccaaag gcgacaccat
     1441 taccgtgttc gacctgcgct tttgcgttcc caacaaagaa atcctgcccg aaaaaggcat
     1501 acacacgctg gagcatttgt tcgcaggttt tatgcgcgac cacttgaacg gcaacggcgt
     1561 ggaaatcatc gacatttccc cgatgggctg ccgcaccggt ttctacatga gccttatcgg
     1621 cacgccttcc gaacagcagg tcgccgatgc gtggctggct tcgatgcagg atgtgggcaa
     1681 tgtcaaagac caaagcaaaa tccccgagtt gaacgaatac caatgcggca cttatcaaat
     1741 gcactcgctc gccgaagcgc agcaaatcgc gcaaaacgtg ttggcgcgca aagtggcggt
     1801 gaacaaaaac gaagagctga cgctggatga agggctgctg aacgcctaat ccgccaaaaa
     1861 tgccgtctga acaagggttt cagacggcat ttgccttttc cgttataatc tggggttgtg
     1921 cgggggcggg ttttaagccg gcatcgtcct tccctatttt tttctgtccc ttatcggttt
     1981 taagcgggtt ttttatgtcc aacagaccta cactcctcct cgttgacgga tcgtcctacc
     2041 tctaccgtgc gtatcacgcg atggggcaaa acctgaccgc acccgacggc gcgccgacgg
     2101 gtgcgctgta tggcgtattg aatatgttgc gccgtttgcg gtcggaatat ccgcacgatt
     2161 attgcgcggt ggtttttgat gcgaaaggca aaaatttccg ccatcaaatg tttgaagaat
     2221 acaaggcgac gcgcccgccg atgcccgacg atttgcgccc gcaggcggaa gcactgccgg
     2281 atttagtgcg cctgacgggc tggccggtat tggtgattgg gcaagtggag gcggacgatg
     2341 tgatcggcac gctggcgaaa cagggggcgg aacatggttt gcgagtcatt gtttcgaccg
     2401 gcgataagga catggcgcag ttggtggatg agcgcgttac gctggtgaac acgatgagca
     2461 gcgaaacgct ggacattgaa ggcgtgaagg caaaattcgg cgtgcgcccc gaccaaatcc
     2521 gcgattatct cgcgctgatg ggcgacaagg tggacaacgt gccgggcgtg gaaaaatgcg
     2581 gcccgaaaac ggcggtgaaa tggctggaag cctacggttc gctggctggt gtgatggaac
     2641 acgcttcgga aatcaagggc aaagtgggcg aaaacctgca agccgcgctg ccccaactgc
     2701 cgctgtcata tgatttggtc acgattaaaa ccgatgtgga cttgcacgcc gagctttcag
     2761 acggcatcga aagcctgcgc cgtactacgc cgaaatgggc gcagctggtt gtcgatttca
     2821 aacgctgggg cttccgcacc tggctgaaag aagcggaatc aaacatgaat accggctcga
     2881 ccgatgattt gttcggcagc gacagcatcg gcgagcaggc ggctttgaat gcggaaatgc
     2941 cgtttgaaaa acaagccgaa aaagccaccg cccccgaaaa actggattat caagccgtta
     3001 ccaccgaagc gcagtttgcc gctttgttgg acaaactgtc gcgggcggac acaatcggca
     3061 tcgatacgga aaccacgtca ttagacgcga tgaacgcctc gctggtcggc atcagcatcg
     3121 ctttccaagc aggcgaagcg gtttacatcc ccgtaggaca cagcctgacc gccgcgcccg
     3181 aacagcttga tttgcaagac gtattaggcc gtctgaaacc gcatttggaa aaccccgccc
     3241 tgaagaaaat cgggcaaaac ctcaaatacg accaacacgt tttcgctaac tacggcatcg
     3301 ccctgaacgg cattgccggc gacgctatgc tcgcttccta catcatcgaa agccatcttg
     3361 gacacggctt ggacgaattg tccgaacgtt ggctgggctt ggaaaccatt acctacgaat
     3421 cattgtgcgg taaaggcgcg aagcaaatca gttttgccga tgtcgccatc gggcaggcga
     3481 ccgaatacgc cgcccaagac gccgatttcg ccttgcgcct cgaagcgcac ctgcgcgcgc
     3541 aaatggacgc caaacagctt gaaatgtatg aaaaaatgga gctgcccgtc gcgcaagtat
     3601 tgtttgaaat ggaacgcaac ggtgtgcaaa tcgaccgcgc cgaactcgcc cgccaaagcg
     3661 cggaactcgg cgccgagctg atgaagctcg aacaagaagc ctacgccgcc gcagggcagc
     3721 cgttcaacct caactcgccc aaacagctgc aagaaatcct gttcgacaaa atgggcatcc
     3781 cgacaaaagg gctgaaaaaa accgccaagg gcggcatttc caccaacgag gccgtgctcg
     3841 aacagctcgc gcccgactac cccctgccta aaatcatcct gcaaaaccgc agcctggcga
     3901 agctcaaatc cacctacacc gacaaactac ccgaaatgat ttcccccaag gacggccgcg
     3961 tgcataccac ctacgcccaa gccgtcgcca ttaccggccg cctcgccagc aacaacccca
     4021 acctgcaaaa catccccatc cgcaccgccg aaggccgccg cgtgcgccgc gcctttaccg
     4081 caccgcaagg cagcgtcatc gtttccgccg actattccca aatcgagctg cgcattatgg
     4141 cgcacctctc cggcgacaaa accctgattg ccgcgttcca aaacggcgaa gacgtacacc
     4201 gccgcaccgc cgccgaagtg ttcggcactg cgcccgaaaa cgtctcgcct gagcaacgcc
     4261 gctacgccaa aaccatcaac ttcggcttaa tctacggtat ggggcaatac ggccttgcca
     4321 aatcattggg catcgacaac ctttccgcca aaaactttat cgaccgctac ttcgcccgct
     4381 accccggcgt cgccgaatac atgcagcgca ccaaagaaca agccgccgcc caaggcttcg
     4441 tcgaaaccct gtttggccgc cgcctctacc tgcccgacat ccgcaacaaa aacgccaacg
     4501 cccgcgccgg agccgaacgc gccgccatca acgcccccat gcaaggcacc gcctccgacc
     4561 ttatcaaacg cgccatgata gacgtgtccc gctggctggt ttcagacgac ctgaagagca
     4621 aactgattat gcaggtgcat gacgaactgg tgctggaagt cgttgaaacc gaactggatt
     4681 ttgtcaaaga aaaactgccg cagattatgg cgaaagtggg cggcggatta ttggatgtac
     4741 cgctggtggc tgaggttggc gtaggggaga attgggaaga ggcacattga ttgaaaggtg
     4801 ttattatgct atctttattt aaataaaatt taatttttgg tatatttttt ctaaatgttc
     4861 ctatagtata gtggattaac aaaaatcagg acaaggcggc gaagccgcag acagtacgaa
     4921 tagtacggaa ccgattcact tggtgcttca gcaccttaga gaatcgttct ctttgagcta
     4981 aggcgcgaca acgccgtact ggtttttgtt aatccgctat attccg
//
LOCUS       DAXIDM010000123         4863 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000123 DAXIDM010000000
VERSION     DAXIDM010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4863
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.123"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(330..1286)
                     /locus_tag="ACFOAE_001816"
     CDS             complement(330..1286)
                     /locus_tag="ACFOAE_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003694155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element ISNgo3 family transposase"
                     /protein_id="HFC6885246.1"
                     /translation="MNIIGLDISKDTIDATLHKTNGSIHYIKFKNNDDGLKQFRLWIK
                     GNRIRKAYIGMEATGIYYEKAADMLSSYYTVYVINPLKIKDYGKSRFNRTKTDKADSN
                     LIADYIKRHQDTLIPYQIPKNKALQKLINLKNQLQQHQKQIKNRLHSTEEDFIRNIHQ
                     DLIDTIQDKMEQVKIAISEQIKKQTDNNHYRNLQTIPSIGKDTASVLYAQLTEKHFKT
                     ANQFVSYAGLSPAIIQSGTSVRGRGRLSRYGNRRLKSTLYMPALCAYRFNAFPKLINN
                     LKKAGKPKMVIIVAIMRKLAKLAYYIVKTGQPYDAERHRLNQ"
     gene            complement(1501..2688)
                     /locus_tag="ACFOAE_001817"
     CDS             complement(1501..2688)
                     /locus_tag="ACFOAE_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zonular occludens toxin family protein"
                     /protein_id="HFC6885247.1"
                     /translation="MAEICLITGTPGSGKTLKMVSMMANDEMFKPDENGIRRKVFTNI
                     KGLKIPHTYIETDAKKLPKSTDEQLSAHDMYEWIKKPENIGSIVIVDEAQDVWPARSA
                     GSKIPENVQWLNTHRHQGIDIFVLTQGSKLLDQNLRTLVRKHYHIASNKMGMRTLLEW
                     KICADDPVKMASSAFSSIYTLDKKVYDLYESAEVHTVNKVKRSKWFYTLPVIVLLIPV
                     FVGLSYKMLSSYGKKQEEPAAQESAATEHQAVFQDKTEGEPVNNGNLTADMFVPTLSE
                     KPESKPIYNGVRQVRTFEYIAGCVEGGRTGCTCYSHQGTALKEITKEMCKDYARNGLP
                     FNPYKEESQGRDVQQSEQHHSDRPQVATLGGKPWQNLMYDNWQERGKPFEGIGGGVVG
                     SAN"
     gene            complement(2689..2973)
                     /locus_tag="ACFOAE_001818"
     CDS             complement(2689..2973)
                     /locus_tag="ACFOAE_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2523 domain-containing protein"
                     /protein_id="HFC6885248.1"
                     /translation="MKLLAALIPLLMSVVGRILTALGLMAVTYSGVDRLVAHFQQAIT
                     HSITGAPQAMLQLFYISGGGTVLNILFGAIAFILSFKQITKLATSIGKKK"
     gene            complement(3276..4781)
                     /locus_tag="ACFOAE_001819"
     CDS             complement(3276..4781)
                     /locus_tag="ACFOAE_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IgG-binding virulence factor TspB family
                     protein"
                     /protein_id="HFC6885249.1"
                     /translation="MCCSLSFAEPARIDDRIIKFRPSKSKFFESTGYRKINNEFSKFT
                     EAANVEHIPTGAKARINAKITASVSRAAVLSGVGKLVRQGAKFSTRAVPYVGTALLAH
                     DVYETFKEDIQARGYQYDTETDKFVKGYEYSNCLWYEDERRINRTYGCYGVDSSIMRL
                     MSDYSRFPEVKELMESQMERLARPYWEKLRNRPDMYYFKNYNFKRCYFGLNGGDCLVA
                     KGDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEV
                     APGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTADVQVIPRPDLTPGSAEAPNAQPL
                     PEVSPAENPANNPNPNENPGTSPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPGRTNG
                     RDGEDGGLLCKFFPDILACDRLPEPNPAEDLNLPSETVNVEFQKSGIFQDSAQCPAPV
                     TFTVTVLDSSRQFAFSFENACTIAERLRYMLLALAWAVAAFFCIRTVSREV"
BASE COUNT         1108 a         1099 c         1087 g         1569 t
ORIGIN      
        1 cataagttcc cgtgcggaca gacctagatt cccacctgtg tgggaatgac gatgcagaag
       61 ttgcccgaaa ctcaaaaaaa acgaaaccga acgaaccgga ttcccgcttt tacgggaatg
      121 acgggatttt gggttgtggt aatttatcgg gaaaacggaa acccctatgc cgtcattccc
      181 gcgcagatga tatgttgccc gtcaacacaa aataaaaaca aagctgcaac atactgattt
      241 atattgttat ttttatttac gtttatttac gatatgcaaa tgcacggtta cacaaatata
      301 ttcgcgtaac cgtttaattt tgttgaatct tattgattca atcggtgtct ttccgcatcg
      361 taaggctggc cggttttaac aatgtaatag gcgagcttcg ccagtttgcg catgatggca
      421 acgatgatta ccatctttgg cttacccgct tttttcagat tatttattaa tttcggaaat
      481 gcgttaaaac ggtaagcaca aagggcgggc atatacagcg tactttttaa tcgtctgttt
      541 ccgtatcggc tcaatctgcc ccgacctctt acgcttgtcc ctgattgtat gatggcggga
      601 cttaatccgg cataggatac aaactggttt gcggttttaa aatgtttttc tgtcagttgc
      661 gcataaagaa ctgatgcggt gtctttgcct atgctcggga tggtttgaag attgcggtaa
      721 tggttattgt ccgtttgttt tttgatttgt tcggatatgg ctatttttac ctgttccatc
      781 ttgtcctgta tggtatctat caagtcttga tgtatgttcc ttatgaagtc ttcttcagtg
      841 ctatgaagac ggtttttaat ttgcttctga tgttgctgta attgattttt aaggttaatc
      901 agtttttgca gtgctttgtt tttgggtatc tgatacggta tcaatgtatc ttgatgcctt
      961 tttatgtaat ctgctatcag gtttgaatct gctttgtcgg ttttggtacg gttaaacctg
     1021 cttttcccgt agtccttgat ttttaaggga ttgataacgt aaacggtata gtaggaagaa
     1081 agcatatctg ctgccttttc gtaatagatg cctgttgcct ccatgccgat ataggctttt
     1141 ctgattctgt ttccctttat ccacaatcta aactgtttta atccatcatc attattctta
     1201 aatttaatgt aatggatact tccgtttgtt ttatgcaatg ttgcgtctat ggtatccttt
     1261 gagatgtcca gcccgattat attcattggt attttcctta tttatacagc cttgatacgg
     1321 ctaggatgat attcaatttt gaggatggat aaaggcagcc ggcatttcta cgcgtctgtt
     1381 ttaatacatt gcgggatttg ctgcctgact gccttagccc ttgctttgcg cgaaacaaag
     1441 acccgtaagc cgtctatatt caaacggttt acgggtcttt tttctctctt gccgttttct
     1501 tcagtttgcc gatccgacca cgcccccgcc gattccttca aacggttttc cgcgctcctg
     1561 ccaattatca tacataagat tttgccacgg ctttccgccc aacgtggcaa cttgcggtct
     1621 gtccgaatgg tgctgctcac tttgctggac atcccgccct tggctttctt ctttatatgg
     1681 gttaaacggc aatccgtttc ttgcgtaatc cttgcacatt tcctttgtaa tttctttcaa
     1741 tgccgtccct tgatgcgaat agcatgtgca tccggttctt ccgccttcta cacagcctgc
     1801 tatatattca aaggttctta cctgccttac accgttataa atcggcttgc tttcgggttt
     1861 ttcggacaat gtcggaacaa acatatctgc ggtaaggtta ccgttgttta ccggctcgcc
     1921 ttctgtttta tcctgaaata ctgcctgatg ttctgttgcc gccgattctt gtgctgcggg
     1981 ttcttcctgt ttttttccgt aactgctcaa cattttatag gacaggccga caaacacggg
     2041 aatcagcaat actattactg gcagagtgta aaaccacttt gaccgcttga ccttatttac
     2101 ggtatgaact tccgctgatt cgtacaagtc ataaactttt ttatccagtg tatagatact
     2161 ggagaatgcg cttgatgcca tttttacggg atcgtccgcg catattttcc attctaaaag
     2221 cgtacgcata cccatcttgt ttgaagcgat gtggtaatgt ttccgtacaa gcgttctaag
     2281 attttgatct agaagcttag agccttgagt caaaacaaat atatcaatgc cctgatgtct
     2341 gtgcgtattc agccattgga cattttcagg gatttttgaa cctgccgagc gtgccggcca
     2401 tacgtcttga gcttcatcta caatgacaat agacccgata ttttcgggct tctttatcca
     2461 ttcgtacata tcatgcgccg aaagctgctc atctgtcgat ttcggcagct ttttcgcgtc
     2521 cgtttctatg taggtgtgcg gtatcttcaa gcctttgatg ttcgtaaata ctttacggcg
     2581 tatgccgttt tcatccggct taaacatttc atcgtttgcc atcatggaaa ccatttttaa
     2641 tgttttccct gaaccgggcg tgccggttat caaacagatc tctgccattt attttttctt
     2701 cccgattgag gttgctagtt ttgttatttg tttgaatgac agaataaagg cgatcgcgcc
     2761 gaaaagaatg tttagaacag taccaccgcc gcttatatag aaaagctgta acattgcttg
     2821 aggtgcgccc gttatgctat gggttatcgc ctgttgaaaa tgggctacca atctatccac
     2881 ccccgaatag gtcacggcca tcaatcccaa tgcagtcaat atacggccta cgacgctcat
     2941 caagagcgga atcaatgcgg ccaacaattt catttgctat ccctttctta aaaggcacgg
     3001 ttgcctcatt aaaaaaatgt ttcttaatct gaaagatttt gcggggacta gcccccacac
     3061 ccccagtctc acttgcgacg ctgcgggggc agggggacgg cgcaaaaagc gcgcgcctta
     3121 ccacctgccc ttgcagcaga gtgtgttctt ttggcggggc ggcaaggggt atccaaaaag
     3181 atttataaag acgataaagc cgtctttaca aatctttctg gacgtcctcc ccctgccttg
     3241 gcacaagtta ctgaagcccg gcggtgctgc gcctgctaga cttcacggga tactgtgcgg
     3301 atacaaaaaa aggcggcaac cgcccaagca agggcgagaa gcatgtacct tagccgttcg
     3361 gctatggtac atgcgttctc aaagctgaac gcgaactgcc tgcttgaatc aagcacagtc
     3421 actgtgaaag tgacaggtgc gggacactgt gcggaatctt gaaagattcc tgatttctga
     3481 aactctacat tgacggtttc agacggcaga tttaaatctt ctgccggatt gggctcgggc
     3541 agcctgtcgc aagcgagaat gtcggggaag aatttgcaca aaaggccgcc gtcttcgccg
     3601 tccctgccgt ttgtgcggcc cggaactgcg ggggaatcgg gtcttgtgcc gggctgtccg
     3661 tccgtatcgg gatttgcatc gggattcaaa tcggggtcgg gttcgggatt ggggctcgtg
     3721 ccggggttct cattggggtt cgggttgttt gcggggtttt cggcgggcga tacttcgggc
     3781 agcggctgtg cgttcggtgc ttccgcgctt ccgggtgtga ggtcgggacg cggaattact
     3841 tgaacatccg ctgtggtgtt gccttgcgaa tccctgccga atgttgcgac aacctgaacg
     3901 ggattcccgt tcctgtccgt gaccggcccc atattcactt ttgttccggg tgcgacttct
     3961 actttttcgg aataaccggg atatccggtt gcctttatgt atttgtcggg attggcatcg
     4021 actttcaacg ataaaatctc ttccagcttt ttggcatcca tttcttcttt gtattttgaa
     4081 tttccttgaa gtgagaaact gataaaagtt ctaccatcat cacctttagc aactaaacaa
     4141 tctccgccgt tcaatccgaa ataacaacgt ttaaaattgt agtttttaaa ataatacata
     4201 tcaggacgat tccttaactt ttcccaatac ggacgggcaa gcctttccat ttggctttcc
     4261 atcaattctt tgacttcggg gaatctgctg taatcggaca taaggcgcat aatcgaactg
     4321 tcaacgccgt agcagccata ggttctatta atacgtcttt cgtcttcgta ccaaaggcaa
     4381 ttactatatt cgtagccttt tacaaatttg tcggtttcgg tgtcgtattg gtagcctcgt
     4441 gcctgtatgt cttctttgaa agtttcgtat acgtcgtggg ctaaaagggc tgtccctaca
     4501 taagggactg cccttgtgct gaatttcgcg ccttggcgga caagtttgcc gactcctgac
     4561 aagacggcgg cgcgggatac gctggcggtt atctttgcgt tgattcgggc ttttgcgccc
     4621 gtggggatat gttcgacatt tgccgcttct gtgaatttag aaaattcatt attgattttt
     4681 ctatatcctg tagattcaaa aaactttgat ttagatggcc taaattttat tattcgatca
     4741 tctattcttg ctggttctgc aaaactaaga gaacaacaca ttaaaatcgg tgttgctatc
     4801 agaaaattcc gagtaaataa attcatgcga aatttttcca ttttcttctg acttcctaat
     4861 aaa
//
LOCUS       DAXIDM010000124         4797 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000124 DAXIDM010000000
VERSION     DAXIDM010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4797
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.124"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..627
                     /locus_tag="ACFOAE_001820"
                     /pseudo
     CDS             1..627
                     /locus_tag="ACFOAE_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153708080.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(763..2166)
                     /locus_tag="ACFOAE_001821"
     CDS             complement(763..2166)
                     /locus_tag="ACFOAE_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HFC6885250.1"
                     /translation="MTLLNLMIMQDYGISVCLTLTPYLQHELFSAMKSYFSKYILPVS
                     LFTLPLSLSPSVSAFTLPEAWRAAQQHSADFQASHYQRDAVRARQQQAKAAFLPHVSA
                     NASYQRQPPSISSTRETQGWSVQVGQTLFDAAKFAQYRQSRFDTQAAEQRFDAAREEL
                     LLKVAESYFNVLLSRDTVAAHAAEKEAYAQQVRQAQALFNKGAATALDIHEAKAGYDN
                     ALAQEIAVLAEKQTYENQLNDYTDLDSKQIEAIDTANLLARYLPKLERYSLDEWQRIA
                     LSNNHEYRMQQLALQSSGQALRAAQNSRYPTVSAHVGYQNNLYTSSAQNNDYHYRGKG
                     MSVGVQLNLPLYTGGELSGKIHEAEAQYGAAEAQLTATERHIKLAVRQAYTESGAARY
                     QIMAQERVLESSRLKLKSTETGQQYGIRNRLEVIRARQEVAQAEQKLAQARYKFMLAY
                     LRLVKESGLGLETVFAE"
     gene            complement(2235..3662)
                     /locus_tag="ACFOAE_001822"
     CDS             complement(2235..3662)
                     /locus_tag="ACFOAE_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HFC6885251.1"
                     /translation="MFFSALKSFLSRYITVWRNVWAVRDQLKPPKRTAEEQAFLPAHL
                     ELTDTPVSAAPKWAARFIMAFALLALLWSWFGKIDIVAAASGKTVSGGRSKTIQPLET
                     AVVKAVHVRDGQHVKQGETLAELEAVGTDSDVVQSEQALQAAQLSKLRYEAVLAALES
                     RTVPHIDMAQARSLGLSDADVQSAQVLAQHQYQAWAAQDAQLQSALRGHQAELQSAKA
                     QEQKLVSVGAIEQQKTADYRRLRADNFISEHAFLEQQSKSVSNWNDLESTRGQMRQIQ
                     AAIAQAEQNRVLNTQNLKRDTLDALRQANEQIDQYRGQTDKAKQRQQLMTIQSPADGT
                     VQELATYTVGGVVQAAQKMMVIAPDDDKMDVEVLVLNKDIGFVEQGQDAVVKIESFPY
                     TRYGYLTGKVKSVSHDAVSHEQLGLVYTAVVSLDKHTLNIDGKAVNLTAGMNVTAEIK
                     TGKRRVLDYLLSPLQTKLDESFRER"
     gene            3898..4251
                     /locus_tag="ACFOAE_001823"
     CDS             3898..4251
                     /locus_tag="ACFOAE_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885252.1"
                     /translation="MFTTNDLRHFLEGLAILFSIGYWDTMLLLLWFLVRFAYKKPKRN
                     PGKILSGSLTTAAILMLFVWIIPKQFGPIKEEIQAQEEWDRKYKEAEAVFNEQCKTAG
                     ERFTRRRTMWKGLCC"
     gene            4375..4785
                     /locus_tag="ACFOAE_001824"
     CDS             4375..4785
                     /locus_tag="ACFOAE_001824"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885253.1"
                     /translation="MGNTAMWMSCNPTIPILFGIQVKIFPLNQILNHIHPARYAVTFE
                     NNVDSKLRRHWVAGATIRIIDRQTDEVIAKKTIYVFEKGLDGTGGARMPWKFAILCNK
                     ERLTSSEPLSDFVLSVLKPYILRPLYIASLRRDD"
BASE COUNT         1162 a         1248 c         1162 g         1225 t
ORIGIN      
        1 tttgattgta cggcagccac catttgctat gcactcaaac agatggggat aacgcgcaaa
       61 aaaagaccac cacttacaaa gaacaagacc cggccaaagt aacgcattat ttgacacagc
      121 cggccgaatt ttccgactac caacgtgttt atttggatga aacaggattt gaccgctacc
      181 tgttccgtcc ctatgcccgc agcctgaaag ggcaaatagt gaaagcgcag ataagtggaa
      241 aaagatacca acgcttatct ttggtgtccg cacaagtcgg caaccggctg attgctccaa
      301 tggtttatca aaatacgatg accggagtct tttttgaagc gtggtttcag caatgcctac
      361 tgcccgcatt gactcaaaaa tcgttgatta ttttagataa tgcgcgattt caccgtatgg
      421 gtgtcttacg ggaaatggcg gaaaaattgg gacataaggt attgcctctt gcaccttatt
      481 cacctgagct caacccgatt gagaaagtgt gggcgaatat taagcggtat ctgcgaaccg
      541 ttttgtctga ttacgcccga tttgacgatg cactactgtc ctattttgat tttaattgaa
      601 tatacatttg aattaactcg cacttaattt aaatgtgttt ttaactgtgc tttatttaaa
      661 ggcaatgaga atgtgaaagt atcggatcaa tcccaaagca gcctgcactt tcgaaacggg
      721 gtgcaggctg ctttgggaat ttcataaccg tttcagcctg ctttattccg caaataccgt
      781 ttccaaccct aacccgctct ctttcaccaa gcgcaaataa gccagcatga atttataccg
      841 tgcttgagcc agtttctgtt ctgcttgggc gacttcctgc cgcgcccgta ttacttccag
      901 ccggttgcgg atgccgtatt gttggccggt ttcggtcgat ttcagtttca aacggctgct
      961 ttccaaaacc cgttcttgcg ccatgatttg gtaacgcgcc gcaccgcttt cggtataagc
     1021 ctggcgtacg gcgagtttga tgtgccgctc ggttgcggtc agctgtgctt cggcggcccc
     1081 gtattgcgct tcggcttcat ggattttgcc cgacaattct ccgccggtat aaagcggcaa
     1141 attcaactgt acgccgacgc tcatcccttt gccccgatag tggtagtcat tattctgcgc
     1201 agatgaagtg tagaggttat tctgatagcc gacatgggca gaaacggtgg gatagcggct
     1261 gttctgtgct gcccgaagcg cctgtccgct gctttgcagg gcaagctgct gcatccggta
     1321 ttcatgattg ttggataagg caatgcgctg ccattcatcc agactgtaac gttccagctt
     1381 gggcagatag cgtgccaaca ggttggcggt atctatggcc tcgatttgtt tgctatccag
     1441 gtcggtgtag tcgttcaact ggttttcata ggtttgtttc tcagccaata cggcgatttc
     1501 ttgggccagg gcattgtcgt aaccggcttt ggcttcgtga atatccagcg cggtggcagc
     1561 acctttattg aataaagcct gcgcctgcct tacctgctgg gcataagcct ctttttccgc
     1621 cgcatgggcg gcaacggtgt ctcggctgag taaaacgttg aaataacttt cggcaacttt
     1681 caacagcaat tcttcgcgtg ccgcatcgaa acgctgttct gcagcctgcg tatcgaacct
     1741 gctttggcgg tattgtgcaa atttggcagc gtcaaataag gtttgtccca cctgcacgct
     1801 ccatccctgt gtttcgcggg tggaagaaat cgatggcggc tggcgctggt agctggcatt
     1861 ggcggataca tggggaagga atgcggcctt ggcttgttgt tgccgtgcgc gcactgcatc
     1921 acgctggtaa tgggacgctt gaaaatcagc cgaatgttgc tgcgccgccc gccatgcttc
     1981 aggcagcgta aaagccgaaa cggatgggga aagggatagt ggcaaggtaa aaagtgaaac
     2041 gggtaggata tatttggaaa aataggattt catagccgaa aatagttcat gttgcaaata
     2101 gggcgtcagt gtcaggcaaa cggaaatacc gtaatcttgc attatcatta gattgagcaa
     2161 tgtcatccgg gcaatggttt caggcagtct gcatgtccga accggcggat aacaaatgcc
     2221 cagtacggat ccgcctatcg ctccctaaag ctttcgtcca atttggtttg cagcgggctt
     2281 aacagataat ccagcacccg ccgtttaccc gttttaatct ccgccgtgac attcatgccc
     2341 gccgtcagat tcactgcttt gccgtcaata ttcaaggtat gtttgtccag cgacaccacc
     2401 gccgtataaa ccaagcccaa ctgttcgtgg cttaccgcat catggctgac acttttcacc
     2461 ttgcccgtca gataaccgta gcgcgtatag ggaaagctct caatcttcac caccgcatcc
     2521 tgtccctgtt ccacaaaacc gatgtctttg ttcaatacca aaacttccac gtccattttg
     2581 tcgtcatcgg gcgcaatcac catcattttt tgggcagcct gcaccacacc gcccaccgta
     2641 taggtggcca attcctgcac cgtgccgtcc gcaggcgact gtattgtcat cagctgctgc
     2701 cgctgctttg ccttatccgt ttggccgcgg tattggtcaa tctgttcgtt tgcttggcgc
     2761 agcgcatcca gcgtatcgcg tttcaggttc tgcgtattca gcacccgatt ctgctccgcc
     2821 tgtgcaatgg ccgcctgaat ctgcctcatc tgaccgcgcg tactttccaa atcgttccaa
     2881 ttgctgaccg atttgctctg ctgctccaaa aacgcatgtt ccgaaataaa attgtcggcc
     2941 cgcaaacggc ggtagtctgc tgttttctgc tgctcgatcg cccccaccga aaccagcttc
     3001 tgctcctgcg ccttggccga ctgcaattcc gcctgatggc cgcgcaaagc cgactgcaat
     3061 tgcgcatcct gcgccgccca tgcctgatac tggtgctgcg ccaacacctg cgccgattgc
     3121 acatcggcat cggagagacc taaagaccgt gcttgcgcca tatcgatatg cggcacggta
     3181 cggctttcca atgccgccaa taccgcttca taacgcagtt tggacaattg ggcagcctgc
     3241 aaagcctgct ccgactgcac cacatcgctg tctgttccca cagcctccag ttccgccagc
     3301 gtttctccct gtttcacatg ctgcccgtcg cgcacatgta ccgccttaac caccgccgtt
     3361 tccagcggct ggatggtttt gctgcgcccg cccgacaccg ttttgcccga agccgccgcc
     3421 acaatatcga ttttgccgaa ccaggaccac aacaaagcca aaagcgcaaa cgccataata
     3481 aaacgcgccg cccatttcgg agcggcagag accggcgtat cggtcagttc caaatgcgcg
     3541 ggcaaaaacg cctgttcttc cgccgtgcgt ttgggcggtt tcaactggtc gcgcaccgcc
     3601 caaacattgc gccatacagt aatgtatcga gaaagaaagg atttcagggc ggagaaaaac
     3661 ataacgggta taaccttggc aatatagaaa caggaaacaa tataaatatg taaaggaatt
     3721 ttaacggaaa gcgcggcagc tgttaaggga aaggcgggaa tattgacaaa aaatacccaa
     3781 gtcgttacaa atattcatta ttttactgcg taacgcaacg ctgaagcgca ggctgctttt
     3841 gagatgcggc aaggttcggc aaaaagcagc ctgcacattt aaccacagga actacccatg
     3901 tttaccacaa acgatttacg ccatttccta gaaggtttgg ccatcctatt ctcaatcggc
     3961 tattgggaca ccatgctgct gttgctttgg tttctcgtcc gctttgccta taaaaagccc
     4021 aaacggaacc ccggcaaaat cctttcaggc agcctgacca ccgccgctat cctgatgctg
     4081 tttgtttgga ttattcccaa acaattcggc ccgatcaaag aagaaataca ggcacaagaa
     4141 gagtgggaca gaaaatacaa agaagccgaa gccgtgttta acgaacaatg caaaacggcg
     4201 ggggaaagat ttaccagacg gcggacaatg tggaagggat tatgctgttg aaggtagtac
     4261 ctgagcgtac cgtttcggca gatgcaaaaa ccagagaccc gatgtgggac aatgcggctt
     4321 tacagaccag cgaaggcgta aattttattg ctcgtttcct aggatttttt agcgatgggg
     4381 aataccgcta tgtggatgtc ctgcaaccca accattccga tattattcgg tattcaggta
     4441 aagatttttc cgctaaatca aatacttaat catatacacc ccgcccgtta tgcggtaacg
     4501 ttcgaaaaca atgtcgattc caagctgcgc aggcactggg tggcaggtgc gaccatacgg
     4561 attatcgacc gccaaactga cgaagtgatt gccaagaaaa ccatctatgt ctttgaaaaa
     4621 ggcttggacg gcacgggtgg ggcgagaatg ccgtggaagt ttgctatctt gtgcaataaa
     4681 gaaagactta cttcttcaga gccgttatcg gattttgttc ttagcgtttt aaaaccttat
     4741 atattgcgtc ccttatatat tgcgtcccta agaagggacg attaacaaaa attaacg
//
LOCUS       DAXIDM010000125         4729 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000125 DAXIDM010000000
VERSION     DAXIDM010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4729
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.125"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(107..322)
                     /locus_tag="ACFOAE_001825"
     CDS             complement(107..322)
                     /locus_tag="ACFOAE_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009348653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885254.1"
                     /translation="MPSENLSDGIFYQSSHIFYQGCKIYPKQQKPPCRHSRKSGNLEP
                     NTAKIYPKQQKSFHRHSRKSGNLERKI"
     gene            complement(340..1278)
                     /locus_tag="ACFOAE_001826"
     CDS             complement(340..1278)
                     /locus_tag="ACFOAE_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003753550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFC6885255.1"
                     /translation="MLELNGLCKRFGGKTVADNICLTVGRGKILAVLGRSGCGKSTLL
                     NMIAGIVRPDGGEIQLNGENITRMPPEKRRISLMFQDYALFPHMSALENAAFGLKMQK
                     MPKAEAERLAMAALAEVGLENEVHRKPEKLSGGEKQRLALARALVVRPSLLLLDESFS
                     SLDTHLRGTLRRMTAERIRKGGIPAVLVTHSPEEACTAADEIAVMHEGKILQCGTPET
                     LVQTPAGVQVARLMGLPNTDDDRHIPQHAVRFDQDGMECRVLSRTCLPESFSLSVLHP
                     EHGILWLNLDMPHAGEISGNDTVRIHIEDREIVRFR"
     gene            complement(1287..2162)
                     /locus_tag="ACFOAE_001827"
     CDS             complement(1287..2162)
                     /locus_tag="ACFOAE_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFC6885256.1"
                     /translation="MPTVHFTESVSKQDLDALFEWAKASYGAKSCWKTLYLNRLPLGN
                     LSPEWAERVKKDWEAGCSESSDGIFLNADGWSDMGGRLQHLARTWNKAGLLHGWRNEC
                     FDLTDGGGNPLFTLERAAFRPFGLLSRAVHLNGLTESDGRWHFWIGKRSPHKAVDPDK
                     LDNIAAGGVSGGEMPSEAVCRESSEEAGLDKTLFPFIRPVSRLHSLRPVSRGVHNEIL
                     YVFDAVLPETFLPENQDGEVACFEKMDIGSLVATMLSGNMMHDAQLVTLDAFCRYGLI
                     DAAHPLSEWLDGIRL"
     gene            complement(2344..2420)
                     /locus_tag="ACFOAE_001828"
     tRNA            complement(2344..2420)
                     /locus_tag="ACFOAE_001828"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2384..2386),aa:Met,seq:cat)
     regulatory      2570..2669
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            2760..4661
                     /gene="thiC"
                     /locus_tag="ACFOAE_001829"
     CDS             2760..4661
                     /gene="thiC"
                     /locus_tag="ACFOAE_001829"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HFC6885257.1"
                     /translation="MTTPKKTAKTSGNEARELADLSEDIGIRFKYPNSERVYLQGSRD
                     DIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGVYGDPAAHIDLKQGLPHIRTAWLDE
                     RGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPE
                     MEFVAIRERLKLDELSQKPEYAKLLKQHAGQSFGANIPTRPDQITPEFVRQEIAAGRA
                     IIPANINHPELEPMIIGRNFRVKINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDL
                     STGAHIHETREWIIRNAPVPIGTVPIYQALEKTGGIAEDLTWDLFRDTLIEQAEQGVD
                     YFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAY
                     DVSFSLGDGLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVK
                     ENMTEELQHCFEAPFYTLGPLVTDIAPGYDHITSGIGAANIGWYGTAMLCYVTPKEHL
                     GLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFRLSLDPE
                     RAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEF
                     VKKGAKIYS"
BASE COUNT         1144 a         1337 c         1244 g         1004 t
ORIGIN      
        1 cccttaaaac agaaaaccga aatcagaaac ctaaaatccc gtcattcccg cgcaggcggg
       61 aatctaggtc tgtcggcacg gaaacttatc gggaaaaacg gtttctttag attttacgtt
      121 ctagattccc gcttttgcgg gaatgacgat gaaaagattt ttgttgtttc ggataaattt
      181 ttgccgtgtt gggttctaga ttcccgcttt tgcgggaatg acggcagggt ggtttctgtt
      241 gtttcggata aattttgcag ccctgataaa aaatatggct gctttggtaa aaaatgccgt
      301 ctgaaaggtt ttcagacggc attttgtttt taagaagcat cagcggaagc ggacgatttc
      361 cctgtcttcg atatggatgc gtaccgtatc gtttcccgat atttcaccgg cgtgcggcat
      421 atcgaggttc agccacagga tgccgtgttc cggatggagg acggacaggc tgaacgattc
      481 gggcaaacag gtacgggata atacgcggca ctccatgccg tcttggtcga aacgcaccgc
      541 atgttgcgga atatggcggt catcgtcggt attgggcaaa cccatcagtc gggcgacctg
      601 cacgccggca ggcgtttgaa ccaaggtttc gggcgtaccg cattgaagga ttttcccctc
      661 gtgcatgacg gcgatttcgt ccgccgccgt gcaggcctct tcgggcgaat gcgttaccaa
      721 aacggcaggg atgccgccct tgcggatgcg ttcggcagtc atgcggcgca gcgtgccgcg
      781 caaatgcgtg tccaaactgg aaaacgattc gtccaacagc agcagggaag ggcggacaac
      841 caaagcgcgc gccagtgcca accgttgttt ctcgcctccg gaaagttttt caggcttgcg
      901 gtgcacctcg ttttccagtc cgacttcggc aagtgccgcc atggcaaggc gttcggcttc
      961 ggctttcggc attttttgca ttttcaaacc gaatgccgca ttttccagcg cactcatatg
     1021 gggaaacagc gcgtaatctt gaaacatcag cgaaatacgg cgtttttcgg gcggcatacg
     1081 ggtaatgttt tccccgttca gctgaatttc gccgccgtcc ggccggacga tgcccgcaat
     1141 catattcagc agggtggatt ttccgcagcc cgaccgcccc agtacggcga gtattttgcc
     1201 gcgcccgaca gtcaggcaga tgttgtcggc aaccgttttg ccgccgaagc gtttgcagag
     1261 tccgttcagt tcaagcatgg cgcatcctat aaacgtatgc cgtccagcca ctcggacagc
     1321 ggatgggcgg catcaatcag accgtaacgg caaaacgcgt ccagcgtaac cagttgcgcg
     1381 tcgtgcatca tgtttcccga caacatggtg gcaaccaagc tgccgatgtc cattttttca
     1441 aaacacgcaa cctcgccgtc ctgattttca ggcaggaagg tttcgggtag gacggcatcg
     1501 aatacataca ggatttcatt gtgcacaccc cggctgacgg ggcgcaggct gtgcagccga
     1561 gataccggac ggataaacgg aaacagcgtt ttatccaaac cggcttcttc gctgctttcg
     1621 cggcacacgg cttcagacgg catttcgccg ccggaaacac cgccggcggc aatattgtcg
     1681 agtttgtcgg gatcgactgc tttgtgcgga ctgcgcttgc ctatccagaa atgccatcgg
     1741 ccgtccgatt cggtcagtcc gttgagatgg acggcgcggc tgagcagtcc gaacggacgg
     1801 aaagcggcgc gttcgagcgt gaacaagggg ttgccgccgc cgtcggtcag gtcgaaacac
     1861 tcgttgcgcc atccgtgaag cagccccgcc ttgttccatg tgcgggcgag gtgctgcaag
     1921 cggccgccca tatctgacca gccgtccgca ttcagaaaaa tgccgtctga agactccgag
     1981 cagcctgcct cccagtcttt tttgacgcgc tccgcccatt ccggcgacag attgcccaaa
     2041 ggcagacggt tcagatacag cgttttccag caactttttg caccgtaact tgcttttgcc
     2101 cactcgaaca gggcatcaag gtcttgtttg ctgacggatt cggtaaaatg gacggtcggc
     2161 atagtcggct ttcttgaaca taatgcggaa gattgtaatc aaaccgcctg aatttgcaac
     2221 cgcaaacaga cggcgggctg ctgttccgat attgcggcag gaaggaaaat ccggcaaaaa
     2281 acggaggcgg caggaaacag gcaaaacaaa acccctcggc attgaaccga ggggtttgat
     2341 atttggttgc gggagcagga ttcgaaccta cgaccttcgg gttatgagcc cgacgagcta
     2401 ccatgctgct ccatcccgcg tcagaaaacg aaactatacg gcagattttt tatgttgtca
     2461 aacattattt ccgcgaaaaa tcataaaatt ttgccgtccg gcggtttatg cctgatttga
     2521 aatatcattt tctttacaaa agttcatgtt cgtgatttaa ttttggttaa catcgaaaca
     2581 ggggtgctgc ctgatgttca ggcggctgag aaataccctt tacacccgat cgggataata
     2641 cctgcgtggg gagttttcac ggattctgtc tttcagacag cattggtttt caaatgccgt
     2701 ctgaaaacgc aaaacgctcc tgtttcttta ttctaaacga gaaaacagga gcatttttta
     2761 tgactacgcc aaaaaaaacc gccaaaactt ccggcaacga agcgcgcgaa cttgccgact
     2821 tgagcgaaga catcggtatc cgcttcaaat atccgaactc ggaacgcgtg tatctgcaag
     2881 gcagccgcga cgacatccgc gtgcctttgc gtgaaatccg tcaggacgac acctacacgg
     2941 cgcaaggcac ggaagccaat ccgccgattc ccgtctatga caccagcggc gtgtacggtg
     3001 atccggcggc acacatcgat ttaaaacaag ggctgcccca catccgcacg gcgtggctgg
     3061 acgaacgcgg cgataccgaa atcctgccca aactctccag cgaatacggc atcgaacgcg
     3121 cgcatgaccc gaaaaccgcc catctgcgtt tcaaccaaat cacccgcccg cgccgcgcca
     3181 aagccggccg caacgtaacc cagctccatt atgcccggca aggcattatc acgccggaaa
     3241 tggaatttgt cgccatacgc gaacgtttaa aattagacga attgtcccaa aaaccggaat
     3301 acgccaaact cttgaaacaa cacgcggggc aaagtttcgg cgcgaacatc ccgacccgtc
     3361 ccgaccaaat cacgcccgaa ttcgtgcgcc aagaaatcgc cgccggacgc gcgattatcc
     3421 ctgccaacat caaccaccca gaactcgaac cgatgattat cggccgcaac ttccgcgtca
     3481 aaatcaacgg caacttgggc aattccgccg taacctccag cctgaccgaa gaagtcgaaa
     3541 aaatggtgtg gtcgctgcgt tggggcgcgg acacgattat ggatttgtcc accggcgcgc
     3601 acatccatga aacgcgcgaa tggattatcc gcaacgcgcc agtccccatc ggcaccgtgc
     3661 ccatctatca ggctttggaa aaaaccggcg gtattgccga agatttgact tgggatttgt
     3721 tccgcgacac cttaatcgaa caggcggagc aaggcgtgga ctatttcacc atacacgcgg
     3781 gcgtattgct gcgttatgtg ccgatgaccg ccaaccgcct caccggcatc gtatcgcgcg
     3841 gcggttcgat tatggcgaaa tggtgtttgg cacatcatcg ggaaaacttc ctttacacgc
     3901 atttcgacga aatctgcgaa atcatgaaag cgtatgatgt gtcgttcagc ctcggcgacg
     3961 gcctgcgccc cggctgcatt gccgatgcca acgacgaatc ccaattcgcc gagctgcaca
     4021 ccttgggcga attgaccgat aaagcgtgga aacatgacgt acaagtcatg atcgaaggcc
     4081 ccggccatgt gccgctgcaa cgcgtcaaag aaaacatgac cgaagagctg caacactgct
     4141 ttgaagcacc tttttacaca ctcggcccgc tcgttaccga catcgcaccc ggctacgacc
     4201 acatcacctc gggcataggc gcggccaata tcggctggta cggcacggcg atgctttgtt
     4261 acgttacccc caaagaacat ttggggctgc ccgacaaaga agacgtgcgc accggcatca
     4321 tcacctacaa actcgccgcc cacgccgccg atctcgccaa aggctggccg ggcgcacaat
     4381 tacgtgacaa cgccctgagc aaggcgcgtt tcgagttccg ctggcgcgac caattccgct
     4441 taagcctcga ccctgaacgt gccgaaagct tccacgacga aaccctgccc gccgaaggcg
     4501 cgaaaatcgc ccacttctgc tcgatgtgcg gccccaaatt ctgctcgatg aaaatcacgc
     4561 aggaagtgcg cgactacgcc gacaagcaaa aagcccaacg gcagggcatg gaggaaaaag
     4621 cggtcgagtt cgtcaaaaaa ggcgcgaaga tttacagttg aaacgtcaag caaaaaatgc
     4681 cgtctgaaac ccggaaaaaa ggcttcagac ggcattcttt cgcttgtga
//
LOCUS       DAXIDM010000126         4669 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000126 DAXIDM010000000
VERSION     DAXIDM010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4669
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.126"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            367..1907
                     /locus_tag="ACFOAE_001830"
     rRNA            367..1907
                     /locus_tag="ACFOAE_001830"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2008..2084
                     /locus_tag="ACFOAE_001831"
     tRNA            2008..2084
                     /locus_tag="ACFOAE_001831"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2042..2044,aa:Ile,seq:gat)
     gene            2090..2165
                     /locus_tag="ACFOAE_001832"
     tRNA            2090..2165
                     /locus_tag="ACFOAE_001832"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2123..2125,aa:Ala,seq:tgc)
     gene            2572..>4669
                     /locus_tag="ACFOAE_001833"
     rRNA            2572..>4669
                     /locus_tag="ACFOAE_001833"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1346 a          989 c         1346 g          988 t
ORIGIN      
        1 gttggaggcg gcgcagtatt tagcagaaat aaaaaacctt atccgacagc gacatgacga
       61 atttccccaa aaaaatccca ctgaaagcat tgaccgtttt tccctgtggg cgtatagttc
      121 ggttcttcgc tgctgcagaa gtggcggacg aactgaaaag tatagcacag aatgttgggg
      181 atatcgagag atatcttgac aggcggaaga aatactttat aattcaaacg ctctttaaca
      241 aaacagatta ccgataagtg tgagtgcctt gagcctcaca ctgtttgaaa gacagacaag
      301 ataatgtttt gaacattgtc ctgtcggttt ctttgaagca gaccagaagt taaaaagtta
      361 gagattgaac ataagagttt gatcctggct cagattgaac gctggcggca tgctttacac
      421 atgcaagtcg gacggcagca cagagaagct tgcttctcgg gtggcgagtg gcgaacgggt
      481 gagtaacata tcggaacgta ccgagtagtg ggggataact gatcgaaaga tcagctaata
      541 ccgcatacgt cttgagagag aaagcagggg actttcgggc cttgcgctat tcgagcggcc
      601 gatatctgat tagctggttg gtggggtaaa ggcctaccaa ggcgacgatc agtagcgggt
      661 ctgagaggat gatccgccac actgggactg agacacggcc cagactccta cgggaggcag
      721 cagtggggaa ttttggacaa tgggcgcaag cctgatccag ccatgccgcg tgtctgaaga
      781 aggccttcgg gttgtaaagg acttttgtca gggaagaaaa ggctgttgct aatatcagcg
      841 gctgatgacg gtacctgaag aataagcacc ggctaactac gtgccagcag ccgcggtaat
      901 acgtagggtg cgagcgttaa tcggaattac tgggcgtaaa gcgggcgcag acggttactt
      961 aagcaggatg tgaaatcccc gggctcaacc cgggaactgc gttctgaact gggtgactcg
     1021 agtgtgtcag agggaggtag aattccacgt gtagcagtga aatgcgtaga gatgtggagg
     1081 aataccgatg gcgaaggcag cctcctggga caacactgac gttcatgccc gaaagcgtgg
     1141 gtagcaaaca ggattagata ccctggtagt ccacgcccta aacgatgtca attagctgtt
     1201 gggcaacctg attgcttggt agcgtagcta acgcgtgaaa ttgaccgcct ggggagtacg
     1261 gtcgcaagat taaaactcaa aggaattgac ggggacccgc acaagcggtg gatgatgtgg
     1321 attaattcga tgcaacgcga agaaccttac ctggtcttga catgtacgga atcctctgga
     1381 gacggaggag tgccttcggg agccgtaaca caggtgctgc atggctgtcg tcagctcgtg
     1441 tcgtgagatg ttgggttaag tcccgcaacg agcgcaaccc ttgtcattag ttgccatcat
     1501 tcagttgggc actctaatga gactgccggt gacaagccgg aggaaggtgg ggatgacgtc
     1561 aagtcctcat ggcccttatg accagggctt cacacgtcat acaatggtcg gtacagaggg
     1621 tagccaagcc gcgaggcgga gccaatctca caaaaccgat cgtagtccgg attgcactct
     1681 gcaactcgag tgcatgaagt cggaatcgct agtaatcgca ggtcagcata ctgcggtgaa
     1741 tacgttcccg ggtcttgtac acaccgcccg tcacaccatg ggagtggggg ataccagaag
     1801 taggtaggat aaccgcaagg agtccgctta ccacggtatg cttcatgact ggggtgaagt
     1861 cgtaacaagg tagccgtagg ggaacctgcg gctggatcac ctcctttcta gagaaagaag
     1921 aggctttagg cattcacact tatcggtaaa ctgaaaagat gcggaagaag cttgagtgaa
     1981 ggcaagattc gcttaagaag agaatccggg tttgtagctc agctggttag agcacacgct
     2041 tgataagcgt ggggtcggag gttcaagtcc tcccagaccc accaagaacg ggggcatagc
     2101 tcagttggta gagcacctgc tttgcaagca gggggtcatc ggttcgatcc cgtttgcctc
     2161 caccaatact gtacaaatca aaacggaaga atggaacaga atccattcag ggcgacgtca
     2221 cacttgacca agaacaaaat gctgatataa taatcagctc gttttgattt gcacagtaga
     2281 tagcaatatc gaacgcatcg atctttaaca aattggaaag ccgaaatcaa caaacaaaga
     2341 caaagcgttt gttttgattt tttattcttt gcaaaggata aaaaatcgct cacaagagaa
     2401 aagaaaacaa acacagtatt tgggtgatga ttgtatcgac ttaatcctga aacacaaaag
     2461 gcaggattaa gacacaacaa agcagtaagc tttatcaaag taggaaattc aagtctgatg
     2521 ttctagtcaa cggaatgtta ggcaaagtca aagaagttct tgaaatgata gagtcaagtg
     2581 aataagtgca tcaggtggat gccttggcga tgataggcga cgaaggacgt gtaagcctgc
     2641 gaaaagcgcg ggggagctgg caataaagca atgattccgc gatgtccgaa tggggaaacc
     2701 cactgcattc tgtgcagtat cctaagttga atacatagac ttagagaagc gaacccggag
     2761 aactgaacca tctaagtacc cggaggaaaa gaaatcaacc gagattccgc aagtagtggc
     2821 gagcgaacgc ggaggagcct gtacgtaata actgtcgaga tagaagaaca agctgggaag
     2881 cttgaccata gtgggtgaca gtcccgtatt cgaaatctca acagcggtac taagcgtacg
     2941 aaaagtaggg cgggacacgt gaaatcctgt ctgaatatgg ggggaccatc ctccaaggct
     3001 aaatactcat catcgaccga tagtgaacca gtaccgtgag ggaaaggcga aaagaacccc
     3061 gggaggggag tgaaacagaa cctgaaacct gatgcataca aacagtggga gcgccctaga
     3121 ggtgtgactg cgtacctttt gtataatggg tcaacgactt acattcagta gcgagcttaa
     3181 ccgaataggg gaggcgtagg gaaaccgagt cttaataggg cgaatagttg ctgggtgtag
     3241 acccgaaacc gagtgatcta tccatggcca ggttgaaggt gccgtaacag gtactggagg
     3301 accgaaccca cgcatgttgc aaaatgcggg gatgagctgt ggataggggt gaaaggctaa
     3361 acaaactcgg agatagctgg ttctccccga aaactattta ggtagtgcct cgagcaagac
     3421 actgatgggg gtaaagcact gttatggcta gggggttatt gcaacttacc aacccatggc
     3481 aaactcagaa taccatcaag tggttcctcg ggagacagac agcgggtgct aacgtccgtt
     3541 gtcaagaggg aaacaaccca gaccgccagc taaggtcccc aatgatagat taagtggtaa
     3601 acgaagtggg aaggcccaga cagccaggat gttggcttag aagcagccat catttaaaga
     3661 aagcgtaata gctcactggt cgagtcgtcc tgcgcggaag atgtaacggg gctcaaatct
     3721 ataaccgaag ctgcggatgc cggtttaccg gcatggtagg ggagcgttct gtaggccgat
     3781 gaaggtgcat tgtaaagtgt gctggaggta tcagaagtgc gaatgttgac atgagtagcg
     3841 ataaagcggg tgaaaagccc gctcgccgaa agcccaaggt ttcctgcgca acgttcatcg
     3901 gcgtagggtg agtcggcccc taaggcgagg cagaaatgcg tagtcgatgg gaaacaggtt
     3961 aatattcctg tacttgattc aaatgcgatg tggggacgga gaaggttagg ttggcaagct
     4021 gttggaatag cttgtttaag ccggtaggtg gaagacttag gcaaatccgg gtcttcttaa
     4081 caccgagaag tgacgacgag tgtctacgga cacgaagcaa ccgataccac gcttccagga
     4141 aaagccacta agcttcagtt tgaatcgaac cgtaccgcaa accgacacag gtgggcagga
     4201 tgagaattct aaggcgcttg agagaactca ggagaaggaa ctcggcaaat tgataccgta
     4261 acttcgggag aaggtatgcc ctctaaggtt aaggacttgc tccgtaagcc ctggagggtc
     4321 gcagagaata ggtggctgcg actgtttatt aaaaacacag cactctgcta acacgaaagt
     4381 ggacgtatag ggtgtgacgc ctgcccggtg ctggaaggtt aattgaagat gtgcaagcat
     4441 cggatcgaag ccccagtaaa cggcggccgt aactataacg gtcctaaggt agcgaaattc
     4501 cttgtcgggt aagttccgac ccgcacgaat ggcgtaacga tggccacact gtctcctcct
     4561 gagactcagc gaagttgaag tggttgtgaa gatgcaatct acccgctgct agacggaaag
     4621 accccgtgaa cctttactgt agctttgcat tggactttga agtcacttg
//
LOCUS       DAXIDM010000127         4555 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000127 DAXIDM010000000
VERSION     DAXIDM010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4555
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.127"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            115..813
                     /locus_tag="ACFOAE_001834"
     CDS             115..813
                     /locus_tag="ACFOAE_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HFC6885258.1"
                     /translation="MKSRQLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGL
                     VEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAHLEPVLSKHAKSFKDDMYLRTEH
                     VVWQKEMLPLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
                     FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTID
                     LLADKVREEQKAAQ"
     gene            complement(870..1874)
                     /gene="amgK"
                     /locus_tag="ACFOAE_001835"
     CDS             complement(870..1874)
                     /gene="amgK"
                     /locus_tag="ACFOAE_001835"
                     /EC_number="2.7.1.221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009312645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramate/N-acetylglucosamine kinase
                     AmgK"
                     /protein_id="HFC6885259.1"
                     /translation="MQRQIKLKNWLQTVYPERDFDLTFAAADADFRRYFRATFSDGSS
                     VVCMDAPPDKMSVAPYLKVQKLFDMVNVPQVLHADTDLGFVVLNDFGNTTFLTAMLQE
                     QGETAHKALLLEAIGELVELQKASREGVLPEYDRETMLREINLFPEWFVAKELGRELT
                     FKQRQLWQQTVDTLLPPLLAQPKVYVHRDFIVRNLMLTRGRPGVLDFQDALYGPISYD
                     LVSLLRDAFIEWEEEFVLDLVIRYWEKARAAGLPVPEAFDEFYRWFEWMGVQRHLKVA
                     GIFARLYYRDGKDKYRPEIPRFLNYLRRVSRRYAELAPLYALLVELVGDEELETGFTF
                     "
     gene            1944..4352
                     /locus_tag="ACFOAE_001836"
     CDS             1944..4352
                     /locus_tag="ACFOAE_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS-assembly protein LptD"
                     /protein_id="HFC6885260.1"
                     /translation="MARLFSLKPLVLALGLCFGTHCAAADAVAAEETDNPTAGGSVRS
                     VSEPIQPTSLSLGSTCLFCSNESGSPERTEAAVRGSGEASIPEDYTRIVADKVEGQSQ
                     VQVRAEGNVVVERNRTTLNTDWADYDQSGDTVTAGDRFALQQDGTLIRGETLTYNLEQ
                     QTGEAHNVRMETEQGGRRLQSVSRTAEMLGEGHYKLTETQFNTCSAGDAGWYVKAASV
                     EADREKGIGVAKHAAFVFGGVPLFYTPWADFPLDGNRKSGLLVPSLSAGSDGVSLSVP
                     YYFNLAPNLDATFAPGVIGERGAVFDGQVRYLRPDYAGQSDLTWLPHDKKSGRNNRYQ
                     AKWQHRHDISDTLQAGVDFNQVSDSGYYRDFYGNKEIAGNVNLNRRVWLDYGGRAAGG
                     SLNAGLSVLKYQTLANQSGYKDKPYALMPRLSADWRKNTGRAQIGVSAQFTRFSHDSR
                     QDGSRLVVYPDIKWDFSNSWGYVRPKLGLHATYYSLNRFGSQEARRVSRTLPIVNIDS
                     GMTFERNTRMFGGGVLQTLEPRLFYNYIPAKSQNDLPNFDSSESSFGYGQLFRENLYY
                     GNDRINTANSLSAAVQSRILDGATGEERFRAGIGQKFYFKNDAVMLDGSVGKKPRSRS
                     DWVAFASSGIGSRFILDSSIHYNQNDKRAENYAVGASYRPAQGKVLNARYKYGRNEKI
                     YLKSDGSYFYDKLSQLDLSAQWPLTRNLSAVVRYNYGFEAKKPIEVLAGAEYKSSCGC
                     WGAGVYAQRYVTGENTYKNAVFFSLQLKDLSSVGRNPADRMDVAVPGYIPAHSLSAGR
                     NKRP"
BASE COUNT         1106 a         1403 c         1193 g          853 t
ORIGIN      
        1 cgaaacgaaa acgtcctttt ccggcggcaa actgtatcaa cacgcggaaa tgcaataaaa
       61 tagccggatt ccgattgatt tccaacatct gtttccaaca tcacggagag ccgtatgaaa
      121 tccagacaac tcgccctcgg cgttgccgcc ctgttcgccc ttgccgcgtg cgacagcaaa
      181 gtccaaacca gcgtccccgc cgacagcgcg cctgccgctt cggcagccgc cgccccggca
      241 gggctggtcg aagggcaaaa ctataccgtc cttgccaacc cgattcccca acagcaggca
      301 ggcaaagtcg aagtccttga gtttttcggc tatttctgtc cgcactgcgc ccacctcgaa
      361 cctgttttga gcaaacacgc caagtctttt aaagacgata tgtacctgcg taccgagcat
      421 gtcgtttggc aaaaagaaat gctgccgctg gcacgcctcg ccgccgccgt cgatatggct
      481 gccgccgaca gcaaagatgt ggcgaacagc catattttcg atgcgatggt caaccaaaaa
      541 atcaagctgc aagagccgga agtcctcaaa aaatggctgg gcgaacaaac cgcctttgac
      601 ggcaaaaaag tccttgccgc ctacgagtcc cccgaaagcc aggcgcgcgc cgacaaaatg
      661 caggagctga ccgaaacctt ccaaatcgac ggtacgccca cggttatcgt cggcggtaaa
      721 tataaagttg aatttgccga ctgggagtcc ggtatgaaca ccatcgacct tttggcggac
      781 aaagtacgcg aagaacaaaa agccgcgcag taagcccgtt tgaaaaatgc cgtctgaaac
      841 ttggttttca gacggcattt tgattgggtt taaaacgtaa agcccgtttc cagttcttca
      901 tcgccgacca gttcgaccaa gagcgcgtag agcggggcga gttcggcata acggcgcgat
      961 acgcggcgca ggtaattgag gaaacgcggg atttcgggac ggtatttgtc tttgccgtcg
     1021 cggtagtaca ggcgtgcgaa gatgcctgca accttcaagt gccgctgcac gcccatccat
     1081 tcgaaccagc ggtaaaactc gtcaaacgct tcggggacgg gcaggccggc agcccgcgcc
     1141 ttttcccagt agcggataac caagtccaag acaaattctt cttcccattc gataaaggca
     1201 tcgcgcaaca gcgacaccaa atcgtaggaa atcgggccgt aaagcgcgtc ttggaagtct
     1261 aaaacgcccg gcctgccgcg cgtcagcatc aggttgcgga cgataaagtc gcggtgcaca
     1321 tagactttgg gctgcgccaa caggggcggc agcagcgtat cgacggtttg ctgccaaagt
     1381 tggcgttgtt tgaatgttaa ttcgcgcccc aattcttttg cgacaaacca ttccgggaac
     1441 aggttgattt cgcgcaacat cgtttcacgg tcatattcgg gcaaaacccc ttcacggctc
     1501 gccttctgca attcgaccaa ctcgccgatt gcctccaaaa gcagggcttt gtgcgccgtt
     1561 tcgccctgtt cctgaagcat tgcggtcaaa aacgtcgtat tgccaaagtc gttcaatacc
     1621 acaaacccca gatccgtgtc cgcgtgcaat acctgcggca cattgaccat gtcaaacagt
     1681 ttctgcactt tcaaataagg tgcgacactc atcttgtcgg gcggtgcatc catgcagacg
     1741 acactgctgc cgtctgaaaa cgttgcacgg aaatagcggc ggaaatcagc atccgccgcc
     1801 gcaaaagtca gatcgaagtc ccgttcggga taaacggtct gaagccaatt tttcagtttg
     1861 atttgtcgtt gcataacagt acgaaagcat ttcaggttac aataaacgct attctaactg
     1921 gcaaaccgac ttgaggggcg attttggctc gtttattttc actcaaacca ctggtgctgg
     1981 cattgggcct ctgcttcggc acgcattgcg ccgccgccga tgccgttgcg gcggaggaaa
     2041 cggacaatcc gaccgccgga ggaagcgttc ggagcgtgtc cgaacccata cagcctacca
     2101 gcctgagcct cggttcgacc tgcctgtttt gcagtaacga aagcggcagc cccgagagaa
     2161 ccgaagccgc cgtccgaggc agcggcgaag catccatccc cgaagactat acgcgcattg
     2221 ttgccgacaa ggtggaagga cagtcgcagg tgcaggtgcg tgccgaaggc aacgtcgtcg
     2281 tcgaacgcaa ccggacgacc ctcaataccg attgggcgga ttacgaccag tcgggcgaca
     2341 ccgttaccgc aggcgaccgg ttcgccctcc aacaggacgg tacgctgatt cggggcgaaa
     2401 ccctgaccta caatctcgag cagcagaccg gggaagcgca caacgtccgt atggaaaccg
     2461 aacaaggcgg acggcggctg caaagcgtca gccgcaccgc cgaaatgttg ggcgaagggc
     2521 attacaaact gacggaaacc caattcaaca cctgttccgc cggcgatgcc ggctggtatg
     2581 tcaaggccgc ttccgtcgaa gccgatcggg aaaaaggcat aggcgttgcc aaacacgccg
     2641 ccttcgtgtt cggcggcgtt ccccttttct atacgccttg ggcggacttc ccgcttgacg
     2701 gcaaccgcaa aagcggcctg cttgttccct cactgtccgc cggttcggac ggcgtttccc
     2761 tttccgttcc ctattatttc aaccttgccc ccaatctcga tgccacgttc gcgcccggcg
     2821 tgatcggcga acgcggcgcg gtctttgacg ggcaggtacg ctacctgcgg ccggattatg
     2881 ccggccagtc cgacctgacc tggctgccgc acgacaaaaa aagcggcagg aataaccgct
     2941 atcaggcgaa atggcagcac cggcacgaca tttccgacac gcttcaggcg ggtgtcgatt
     3001 tcaaccaagt ctccgacagc ggctactacc gcgactttta cggcaacaaa gaaatcgccg
     3061 gcaacgtcaa cctcaaccgc cgtgtatggc tggattatgg cggcagggcg gcgggcggca
     3121 gcctgaatgc cggcctttcg gttctgaaat accagacgct ggcaaaccaa agcggctaca
     3181 aagacaaacc gtatgccctg atgccgcgcc tttccgccga ttggcgcaaa aacaccggca
     3241 gggcgcaaat cggcgtgtcc gcccaattta cccgcttcag ccacgacagc cgccaagacg
     3301 gcagccgcct cgtcgtctat cccgacatca aatgggattt cagcaacagc tggggttacg
     3361 tccgtcccaa actcggactg cacgccacct attacagcct caaccgcttc ggcagccaag
     3421 aagcccgacg cgtcagccgc actctgccca tcgtcaacat cgacagcggc atgaccttcg
     3481 aacgcaatac gcggatgttc ggcggcggag tcctgcaaac cctcgagccg cgcctgttct
     3541 acaactatat tcctgccaaa tcccaaaacg acctgcccaa tttcgattcg tcggaaagca
     3601 gcttcggcta cgggcagctt tttcgtgaaa acctctatta cggcaacgac aggattaaca
     3661 ccgcaaacag cctttccgcc gccgtgcaaa gccgtatttt ggacggcgcg acgggggaag
     3721 agcgtttccg cgccggcatc gggcagaaat tctacttcaa aaacgacgca gtcatgcttg
     3781 acggcagtgt cggcaaaaaa ccgcgcagcc gttccgactg ggtggcattc gcctccagcg
     3841 gcatcggcag ccgcttcatc ctcgacagca gcatccacta caaccaaaac gacaaacgcg
     3901 ccgagaacta cgccgtcggt gcaagctacc gtcccgcaca gggcaaagtg ctgaacgccc
     3961 gctacaaata cgggcgcaac gaaaaaatct acctgaagtc cgacggttcc tatttttacg
     4021 acaaactcag ccagctcgac ctgtccgcac aatggccgct gacgcgcaac ctgtcggccg
     4081 tcgtccgtta caactacggt tttgaagcca aaaaaccgat agaggtgctg gcgggtgcgg
     4141 aatacaaaag cagttgcggc tgctggggcg cgggcgtgta cgcccaacgc tacgttaccg
     4201 gcgaaaacac ctacaaaaac gctgtctttt tctcacttca gttgaaagac ctcagcagtg
     4261 tcggcagaaa ccccgcagac aggatggatg tcgccgttcc cggctatatc cccgcccact
     4321 ctctttccgc cggacgcaac aaacggccct gaccgtcgga aacccggcag gagcaccgtt
     4381 cccgcacaag acggcattcc accgacaacc ccaaacccgc catcaaaggc aggattcaaa
     4441 cgataaggaa agaatgatga aaatcaaagc cctgatgatt gccgccgcat tgctggcagc
     4501 agccgatgtc cacgccgcac cgcaaaaggc aaaaaccgca tccgccaaag ctgcc
//
LOCUS       DAXIDM010000128         4513 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000128 DAXIDM010000000
VERSION     DAXIDM010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4513
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.128"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..616
                     /locus_tag="ACFOAE_001837"
     CDS             <1..616
                     /locus_tag="ACFOAE_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885261.1"
                     /translation="HPKSTIKMAKKPNKPFRLTPKLLIRVVLLICITAIGALAIGIVS
                     TFNPNGGKTLQTEPQHTDSPRETEFWLPNGVVGQDAAQPEHHHAASSEPAQPDGTDES
                     GSGLPSPAAPKKNRVKPQPADTAQTDRQPDDAGTQAENTLKETPVLPTNVPRPEPRKE
                     TPEKQAQPKETPKEKETPKENHTKPDTPKNTPPKPHKEILDNLF"
     gene            656..1435
                     /gene="map"
                     /locus_tag="ACFOAE_001838"
     CDS             656..1435
                     /gene="map"
                     /locus_tag="ACFOAE_001838"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003677158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFC6885262.1"
                     /translation="MNGIIIKTPEEIEKMRELGKLVAEALDYIGQFVKPGVTTDEIDK
                     LVYDYHVNVQGGYPAPLHYGNPPYPKSCCTSVNHVICHGIPDDKPLKEGDIINIDLTI
                     KKDGFHGDSSRMFTVGKVSPIAQRLIDVTHASMMAGIEAVKPGATLGDVGYACQQVAE
                     NAGYSVVQEFCGHGIGRGFHEAPQVLHYGKKGQGPVLKPGMIFTVEPMINQGKRHLRI
                     LNDGWTVVTKDRSLSAQWEHEVLVTETGYEILTVSPASGKP"
     gene            1590..1889
                     /locus_tag="ACFOAE_001839"
     CDS             1590..1889
                     /locus_tag="ACFOAE_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC6885263.1"
                     /translation="MKIFENIEDVKAIRKKTGLNQIDFWGKVGVTQSGGSRYETGRKM
                     PKPVRELLRLVHIECIDLAKVNKKDMEIAALLKKHHPDLYAELSKQTKSERKKQS"
     gene            2127..2501
                     /locus_tag="ACFOAE_001840"
     CDS             2127..2501
                     /locus_tag="ACFOAE_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HFC6885264.1"
                     /translation="MKLLTTAILSSAIALSSMAAAAGTNNPTVAKKTVSYVCQQGKKV
                     KVTYGFNKQGLTTYASAVINGKRVQMPVNLDKSDNVETFYGKEGGYVLGTGVMDGKSY
                     RKQPIMITAPDNQIVFKDCSPR"
     gene            complement(2688..4154)
                     /locus_tag="ACFOAE_001841"
     CDS             complement(2688..4154)
                     /locus_tag="ACFOAE_001841"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate:quinone oxidoreductase"
                     /protein_id="HFC6885265.1"
                     /translation="MAEATDVVLVGGGIMSATLGVLLKELEPSWEITLIERLEDVALE
                     SSNAWNNAGTGHSALCELNYAPLGANGIIDPARALNIAEQFHVSRQFWATLVAEGKLE
                     DNSFINAVPHMSLVMNEDHCSYLQKRYDAFKTQKLFENMEFSTDRNKISDWAPLMMRG
                     RDENQPVAANYSAEGTDVDFGRLTRQMVKYLQGKGVKTEFNRHVEDIKRESDGAWVLK
                     TADTRNPDGQLTLRTRFLFLGAGGGALTLLQKSGIPEGKGYGGFPVSGLFFRNSNPET
                     AEQHNAKVYGQASVGAPPMSVPHLDTRNVDGKRHLMFGPYAGFRSNFLKQGSLMDLPL
                     SIHMDNLYPMLCAGWANMPLTKYLLGELRKTKEERFASLLEYYPEANPDDWELITAGQ
                     RVQIIKKDSEKGGVLQFGTEIVAHADGSLAALLGASPGASTAVPLMIRLMHQCFPERA
                     PSWEGRLKELVPGYGIKLNENPERADEIIAYTAKVLDI"
BASE COUNT         1237 a         1321 c         1070 g          885 t
ORIGIN      
        1 acaccccaaa agcacaatca aaatggcaaa aaaaccgaac aaacccttca ggctgacccc
       61 caaactcctg atacgcgtcg tattgctcat ctgtatcacc gccatcggcg cattggcaat
      121 aggcatcgtc agcacattca acccgaacgg cggcaaaacc ctccaaaccg aaccgcaaca
      181 caccgacagc ccccgcgaaa ccgaattctg gctgccaaac ggcgtagtcg gacaagatgc
      241 cgcccaaccc gaacaccacc acgccgcctc atccgaaccc gcacagccgg acggcacaga
      301 cgaaagcggc agcggactgc cgtcccctgc cgcacccaag aaaaaccggg tcaaaccgca
      361 acctgccgac acagctcaaa ccgacaggca gccggacgac gccggaacac aagctgaaaa
      421 cacactcaaa gaaacccccg tactgcccac aaacgtcccc cgtcccgaac cccgaaaaga
      481 aacacccgaa aaacaggcgc agcccaaaga aacacccaaa gaaaaagaaa cgcccaaaga
      541 aaaccatacc aaaccggaca ccccgaaaaa cacgccgccc aaaccccata aagaaattct
      601 cgacaacctc ttctgacccg gcacggcagg cacacccgca atccaaggaa gcattatgaa
      661 cggcatcatc atcaaaaccc ccgaagaaat cgaaaaaatg cgcgagctgg gcaaactcgt
      721 cgccgaagcc ctcgactaca tcggacaatt cgtcaaaccc ggcgtaacca ccgacgaaat
      781 cgacaaactc gtttacgact accacgtcaa cgtccaaggc ggctatcccg cccccctgca
      841 ctacggcaac ccgccctacc ccaaatcctg ctgcacctcc gtcaaccacg tcatctgcca
      901 cggcattccc gacgacaagc cgctcaaaga aggcgacatt atcaacatcg acctcaccat
      961 caaaaaagac ggcttccacg gcgactccag ccgtatgttt accgtcggca aagtctcccc
     1021 catcgcccaa cgcctgatcg acgtaaccca cgcctccatg atggcgggca tagaagccgt
     1081 caaacccggc gcgacactgg gcgacgtagg ttacgcctgc caacaggttg ccgaaaacgc
     1141 cggctattcc gtcgtacagg aattctgcgg acacggcatc gggcgcggtt tccacgaagc
     1201 cccgcaagtg ttgcactacg gaaaaaaagg acagggcccc gttctaaaac cgggtatgat
     1261 ttttaccgtc gaaccgatga tcaaccaagg caaacgccac ctgcgtatcc tcaacgacgg
     1321 ctggacggtg gttaccaaag accgctccct ctccgcccaa tgggaacacg aagtcttggt
     1381 gaccgaaacc ggctacgaaa tcctcaccgt cagccccgcc tccggcaaac cctgaagccg
     1441 gacgtatccg ccccataaaa acaaacaatg ccgtctgaaa gaaacggcag atatgatata
     1501 taatataaaa acaggcttga cccggcacat tacgaaaaca aagcaaatcg gaatttgccc
     1561 cgcaaccaga caaacttaaa ggaagtttta tgaaaatatt tgaaaatata gaagatgtta
     1621 aagccatccg taaaaagacc gggctgaacc agatagactt ctggggcaag gtcggcgtta
     1681 cccagtctgg aggctcgcgc tacgaaaccg gccgcaaaat gcccaaaccc gtacgcgaac
     1741 tgctccgcct cgtccatatc gaatgcatcg atttggcgaa agtcaacaaa aaagatatgg
     1801 aaatcgccgc cctgttgaaa aaacaccatc ccgacctgta tgccgaattg tccaaacaga
     1861 ccaagtccga aagaaaaaaa caaagttaaa ccgcaacctc cggatgcccg acagtttttc
     1921 atttccgaaa aacgcaaaca atgccgtctg aaacaccgga caggccgccg tatcccgcct
     1981 gccgcccctg cctcaaaccg ccgaaccgcc cgaacccgcc tttttacaaa ctttatccaa
     2041 tttcctgttt atttcaggat acgccgacat tagaatgtca aacagctcga aacgggcaaa
     2101 ctccacatcc atccaaagga ataaaaatga aacttctgac caccgcaatc ctgtcttccg
     2161 caatcgcgct cagcagtatg gctgctgctg ccggcacgaa caaccccacc gttgccaaaa
     2221 aaaccgtcag ctacgtctgc cagcaaggta aaaaagtcaa agtaacctac ggcttcaaca
     2281 aacagggtct gaccacatac gcttccgccg tcatcaacgg caaacgtgtg caaatgcctg
     2341 tcaatttgga taaatccgac aatgtggaaa cattctacgg caaagaaggc ggttatgttt
     2401 tgggtaccgg cgtgatggat ggcaaatcct accgcaaaca gcccattatg attaccgcac
     2461 ctgacaacca aatcgtcttc aaagactgtt ccccacgtta atcaggcaac aaaaaacagc
     2521 gttttcagaa atgaaaacgc tgttttttga ccgttccatt attcgcaaaa gggaaaaaac
     2581 gattacctgc cccgtgtacc aaaacctgcc ctgccggatg aagggcataa ccggcaggga
     2641 cggcgtcaac accatatggg ggtacggctt ttcttgaaag attcggctta aatatccaac
     2701 actttcgcgg tataggcgat aatttcatcc gccctttcgg ggttttcgtt caacttgatg
     2761 ccgtaacccg gtaccagctc tttcagacgg ccttcccaag acggggcgcg ctcggggaag
     2821 cattggtgca tcagccggat catcagcggc acagcggtcg atgcgcccgg cgacgcgccc
     2881 agcaatgcgg cgagtgagcc gtcggcgtgg gcgacaatct ccgtaccaaa ctggagcacg
     2941 ccgccttttt cggagtcttt tttaatgatt tggacgcgtt gccctgcggt gatgagttcc
     3001 cagtcgtcgg ggtttgcctc ggggtagtat tccagcaggg aggcgaagcg ttcttctttg
     3061 gttttacgca attcgcccag caggtatttg gtcagcggca tattcgccca gccggcgcac
     3121 agcataggat agaggttgtc catatggatg gacagcggca aatccataag cgagccttgc
     3181 ttgaggaagt tggaacggaa gcctgcgtaa gggccgaaca taaggtggcg tttgccgtcc
     3241 acgttgcgtg tgtcgaggtg cgggacggac atcggcggcg cgccgacgga agcctgcccg
     3301 tacactttgg cgttgtgttg ttcggcggtt tcggggttgc tgttgcggaa gaacaggccg
     3361 gacacgggga agccgccgta gcctttgcct tcggggatgc cggatttttg cagcagggtc
     3421 agcgcgccgc cgcccgcgcc gaggaagagg aagcgggtac ggagggtgag ctgcccgtcg
     3481 gggttgcggg tatcggcggt tttgagcacc cacgcgccgt cggattcgcg tttgatgtct
     3541 tcgacgtggc ggttgaactc ggtttttacg cccttgccct gcaaatattt caccatttgg
     3601 cgcgtcagcc gtccgaaatc gacatccgta ccttcggcgg agtagttggc ggcgacgggt
     3661 tggttttcgt cccggccgcg catcatcagc ggagcccaat cggaaatttt gttccgatcg
     3721 gtggaaaatt ccatattttc aaaaagtttt tgggttttaa acgcgtcata acgtttttga
     3781 agataagaac aatggtcttc attcatcacc aaagacatat gcggcacggc attgatgaag
     3841 gaattgtctt ccaacttgcc ttccgcgacc agcgtcgccc aaaactggcg gctgacatga
     3901 aactgttcgg caatattgag ggcgcgcgcc ggatcgataa tcccatttgc acccaacggc
     3961 gcatagttca attcgcacag cgcggaatgc cccgtgccgg cgttgttcca cgcgtttgac
     4021 gattccaacg ccacatcttc caagcgttca atcagggtga tttcccaaga cggttcgagt
     4081 tctttgagca aaacgcccaa agtcgcgctc ataatgcctc cgcccaccaa gacaacgtct
     4141 gtcgcttcag ccatggttta ctcctaaaaa acaggcatct tctgccctta tggttatttg
     4201 ccgtactaca aacgcctgaa tcgcaaaagc agggaaaacc ggcaatggtg tgtgtccgag
     4261 tatgctgttt cggggttgga atgcgttgca agcatggctt ccgacaccgc ttcaggggct
     4321 tgtaatatgt tatcgtgaat gtagtggatt ttactgggaa atgcaaagtt tttctgtcgc
     4381 ccgccaagtc gggaaactgc gaaatgaaaa ataaaaatag ttatttatct atatatatca
     4441 aatttttaat agataaaaaa tcaaaattgt ttatatatta atttttaaaa gattgtcagc
     4501 atattgcgtt aag
//
LOCUS       DAXIDM010000129         4496 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000129 DAXIDM010000000
VERSION     DAXIDM010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4496
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.129"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..148
                     /locus_tag="ACFOAE_001842"
                     /pseudo
     CDS             1..148
                     /locus_tag="ACFOAE_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(158..1267)
                     /gene="mltB"
                     /locus_tag="ACFOAE_001843"
     CDS             complement(158..1267)
                     /gene="mltB"
                     /locus_tag="ACFOAE_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HFC6885266.1"
                     /translation="MKKRKILPLAICLAALSACTAMEARPPRANEAQAPRADEMKKES
                     RPAFDAAAVFDAAAVPVSDSGFAANANVRRFVDDEVGKGDFSRAEWQDFFDKAAYKAD
                     IVKIMHRPSTSRPWYVFRTGNSGKAKFRGARRFYAENRALIDDVAQKYGVPAELIVAV
                     IGIETNYGKNTGSFRVADALATLGFDYPRRAGFFQKELVELLKLAKEEGGDVFAFKGS
                     YAGAMGMPQFMPSSYRKWAVDYDGDGHRDIWGNIGDVAASVANYMKQHGWRTGGKILV
                     SATLAPGADVQAIIGEKTALTRTVADLKAYGIIPGEELADDEKAVLFKLETAPGVFEY
                     YLGLNNFYTVWQYNHSRMYVTAVRDIANSLGGPGL"
     gene            complement(1176..1427)
                     /locus_tag="ACFOAE_001844"
     CDS             complement(1176..1427)
                     /locus_tag="ACFOAE_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885267.1"
                     /translation="MPLDGIFGGGRQISGGAKGNARHSAKPPIAADTAFRAAPLRRFP
                     TYPICSEHIYEKEKNTAAGNLFGGFVCLYGDGGTPAPGK"
     gene            complement(1468..2895)
                     /locus_tag="ACFOAE_001845"
     CDS             complement(1468..2895)
                     /locus_tag="ACFOAE_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HFC6885268.1"
                     /translation="MIHTEPSAQPSTMDTAAFLKHIESAFRRIFSDGIDLMRYLPEDK
                     WLALKQAGLLLPFLDKKHGGRKGSQFEIQEVLRIAGHYGVPVTLRTGIEGALVLQPLQ
                     EFGDEAQIAQGLDMVFKGEGGGLGVTEPETSGAAIAREMQSYYEYTDGQTIYVNAAKY
                     WQGNSQSDFLLVAAKERKNGKLAKVIDLLLVPKTYIRCETLASEGLRAVRYAVNRIDA
                     EMPATAVMKLSQSDAAGLRAFQNIFIRSRLQLIGMTHGIMEYILENLERYVRNDIRFV
                     DYERREIRRRHQVSEILYRYVCHSVSPVAPVAHQLMEANIVKTLATEYTYAAAQMLQK
                     LLGAKGFERGHTAGNIAIDIRPFTIFEGPNDMLYAEIYDQFVRATAEEKEAGMKLDKN
                     QTLLDRLQTDARFAAVARDYTLPEDIRSFLQEHTLTDACALQKVFIGKIIARLFVFVQ
                     AEHEDAAACLLNDIRKDILDCRYCG"
     gene            3080..>4496
                     /locus_tag="ACFOAE_001846"
     CDS             3080..>4496
                     /locus_tag="ACFOAE_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFC6885269.1"
                     /translation="MTYPIPKPREKSRWSNLSQGSLPLALARYLPHKRLKVVLTQDAE
                     QALRLQTAWRFFRPHDTAVFLPDWETLPYERFSPHQDLVSERLSALWQIKSGAADVLF
                     VPVATAMQKLPPVPFLAGRTFWLKTGQTLDIGRLKTDLVDAGYNHVSHVVAAGEFAVR
                     GGIVDLFPMGSEMPYRIDLFDDEIDSIKTFDTDTQRTISPVSEIRLLPAHEFPTDSEA
                     QKIFRSRFREEVDGNPNDAAVYKAVSNGHFGAGVEYYLPLFFENELETLFDYIGEDAL
                     FVSLGDVHAEANRFWSDVKSRYAMAQGDETYPPLLPQHLYLSADVFAGRLKNYGQVLP
                     DVSGKEHILPDLAVNRQSDEPLQALKDFQTTFDGRILLCAESLGRRETMLGFLQQNGL
                     KAKPVSDWQGFLSAHEPLMITVAPLAYGFKLGGLQSPNQQQTTSASEGEGDAVTDQTE
                     FSASATNPLPSPLPQEREQSAA"
BASE COUNT          951 a         1271 c         1240 g         1034 t
ORIGIN      
        1 tgcaaaaatg ccgtccgaac cgaaacgtgg ttcagacggc attttatagt ggattaacaa
       61 aaatcaggac aaggcgacga agccgcagac agtacaaata gtacggcaag gcaaggcaac
      121 gccgtactgg tttaaattta atccactata aaaaacatta caatcccggg ccgccaagcg
      181 aattggcaat gtccctgacc gccgttacat acatccggct gtggttgtac tgccataccg
      241 tataaaaatt gttcaagccc aaataatatt caaacacgcc gggtgcggtt tccagtttga
      301 acaaaaccgc cttttcatca tcggcaagct cttcgccggg gatgatgccg tacgccttca
      361 aatccgccac cgtccgcgtc agggcggttt tttcgccaat gattgcctga acatccgcac
      421 ccggcgccaa tgttgcagac accagtattt tcccgcccgt gcgccaaccg tgctgcttca
      481 tataattggc aaccgatgcc gcgacatcgc cgatgttgcc ccatatgtcc cgatgtccgt
      541 ccccgtcata atccaccgcc catttccggt agctcgaagg cataaattgc ggcatcccca
      601 ttgcgcccgc atagctgcct ttaaaggcga aaacatcgcc gccttcttct tttgccagct
      661 ttaaaagctc gaccaattct ttttggaaaa acccggcgcg gcgggggtaa tcaaagccta
      721 aggtcgccaa tgcgtccgcc acacggaaac tgcccgtatt tttgccgtaa ttcgtttcaa
      781 tcccgataac cgccacgata agttcggcag gcacgccgta tttttgcgcc acatcatcga
      841 taagcgcgcg gttttccgca taaaaccggc gcgcgccgcg aaatttcgcc ttgcccgaat
      901 ttcccgtgcg gaacacatac cacggacgcg atgtggaggg gcggtgcata atcttgacga
      961 tgtccgcctt gtaagccgct ttgtcaaaaa aatcctgcca ttccgcccgg gaaaaatccc
     1021 ctttcccgac ttcatcgtcc acaaaacggc ggacatttgc attggcggca aacccgctgt
     1081 cggataccgg tacggctgcc gcgtcaaata cggctgccgc gtcaaacgcg gggcggcttt
     1141 cttttttcat ttcatccgcg cggggggctt gggcttcatt tgcccggggc gggcgtgcct
     1201 ccatcgccgt acaggcagac aaagccgcca aacaaattgc cagcggcagt atttttctct
     1261 ttttcataaa tatgttccga acaaataggg taagtgggaa agcggcgcaa gggcgcggcg
     1321 cgaaatgcgg tatccgccgc aatcggcggc tttgcagaat gccgcgcgtt gccttttgcg
     1381 ccgcccgaaa tctgcctgcc gccgccgaaa atgccgtcta aaggcacttc ccctttcaga
     1441 cggcattgcc tgcgccgtat ttgcccgcta tccgcaatat cggcagtcca atatgtcttt
     1501 gcggatatcg ttcagcaggc aggctgccgc gtcttcgtgt tccgcctgta cgaagacaaa
     1561 gagtcgggcg atgattttgc cgataaagac tttttgcagg gcgcaggcgt cggtcagcgt
     1621 gtgttcctgc aggaagctgc ggatgtcttc gggtaaggtg taatcacggg caacggcggc
     1681 aaagcgggca tcggtttgca ggcggtcgag cagggtttgg tttttgtcca acttcatgcc
     1741 tgcttctttt tcttcggcgg tggcgcggac aaactggtcg taaatttcgg cataaagcat
     1801 atcgttcggg ccttcaaaaa tcgtgaaggg gcggatgtcg atagcgatat tgccggcggt
     1861 gtgtccgcgt tcaaaaccct tcgcgcccaa gagtttttgc aacatttgcg cggcggcgta
     1921 agtgtattcc gtggcgaggg ttttgacgat gttcgcctcc atcagctgat gggcgacggg
     1981 ggcaacaggc gaaacggaat ggcagacgta gcggtaaaga atctcggaaa cctgatggcg
     2041 gcgccggatt tcgcggcgtt cgtaatcgac gaatctgatg tcgttgcgga cgtatcgttc
     2101 caggttttca aggatgtatt ccataatgcc gtgcgtcatg ccgatcagtt gcaggcggct
     2161 gcggataaag atgttttgga acgcgcgcaa accggcagcg tcgctctggg agagtttcat
     2221 cacggcggtt gcaggcattt cggcatcgat gcggttgacg gcgtaacgga cggcgcgcaa
     2281 gccttcggat gcgagggttt cgcagcggat gtatgttttg gggacgagca gcaggtcgat
     2341 gactttggcg agtttgccgt ttttgcgttc tttggcggca acgaggagga agtcgctttg
     2401 cgagttgccc tgccagtatt ttgcggcgtt gacgtaaatg gtttgtccgt cggtatattc
     2461 gtagtaagac tgcatttctc gggcaatcgc cgcgccggag gtttcgggtt cggtaacgcc
     2521 caaaccaccg ccctcgcctt tgaaaaccat gtccaaaccc tgtgcgattt gcgcttcatc
     2581 gccgaactct tgcagtggct gcaacaccag cgcgccttcg atgccggtac gcagcgtaac
     2641 gggcacgccg taatgccccg caatccgcaa gacttcctga atttcaaact ggctgccctt
     2701 gcgcccgccg tgttttttgt cgaggaaggg caacagcaaa cccgcctgct tcaaggcaag
     2761 ccatttgtct tcgggcaggt atcgcatcag gtcgataccg tctgaaaaaa tgcggcggaa
     2821 tgcggattcg atgtgcttta aaaaagcagc cgtgtccata gttgacggct gcgcgctcgg
     2881 ttcggtgtgt atcatcggct tcctctgtcg gttcccatta atcggcggcc ggtcaaaccg
     2941 cctgccacag tttagagttg attttctaaa ctttaccaca aagtgcgccg ggcaacaatc
     3001 cgccgacctt tcagacggca tcgcgccccc tcccgtgcta aaatgaccgt ttgcatcact
     3061 gtccgccgat tgccgcacta tgacctaccc catccccaaa ccccgtgaaa aatcccgttg
     3121 gtccaatctt tcgcaaggct cgctgccctt ggctttggcg cgttatctgc cgcataagcg
     3181 gctcaaggtc gtgctgaccc aagatgcgga acaggcgcta cgccttcaga cggcatggcg
     3241 gtttttccgt ccgcacgaca cggcggtgtt cctgccggac tgggaaacgc tgccttacga
     3301 gcgtttttcg ccgcatcagg atttggtgtc ggaacggctg tcggcgttgt ggcagattaa
     3361 gagcggcgcg gcggacgtgt tgttcgtgcc ggttgccacg gcgatgcaga agctgccgcc
     3421 cgtgccgttt ctggcagggc gcacgttttg gctgaaaaca gggcagactt tggatatagg
     3481 ccgtctgaaa accgatttgg tagatgcggg ctacaaccat gtttcccatg ttgttgcggc
     3541 gggcgagttt gccgtgcgcg gcggcattgt cgatttgttc cccatgggca gcgaaatgcc
     3601 ctaccgcatc gatttgtttg acgatgaaat cgacagcatc aaaacctttg atacggacac
     3661 gcagcgcacc atctcccccg tttccgaaat ccgcctgctg ccggcgcacg aattccccac
     3721 cgacagcgag gcgcaaaaaa tcttccgcag ccgcttccgc gaggaagtcg acggtaatcc
     3781 gaacgatgcc gccgtgtaca aagccgtcag caacggccac ttcggtgcgg gcgtggaata
     3841 ttacctgccg ctgttttttg aaaacgagct ggaaacgctg tttgactata tcggcgagga
     3901 tgcgctgttt gtctctttgg gcgatgttca cgccgaggca aaccgctttt ggagcgacgt
     3961 caaatcgcgt tacgccatgg cgcagggcga tgaaacttat ccgcctttgc ttccacagca
     4021 tttgtatctc tctgccgatg tattcgcagg ccgtctgaaa aactacggac aagtgctgcc
     4081 cgatgtttcc ggcaaggaac acatcctgcc cgaccttgcc gtcaaccgcc aatccgacga
     4141 gccgttgcag gcattgaagg attttcagac gacctttgac gggcggattt tgctgtgcgc
     4201 cgaaagcttg ggacggcgcg aaaccatgct cggtttcttg cagcaaaacg gtttgaaagc
     4261 caaacctgtg tccgactggc agggcttctt gtcggcgcat gagccgctga tgattacagt
     4321 ggcgccgttg gcttacgggt ttaaactggg cggactgcaa tcgccgaacc aacagcaaac
     4381 tacttccgcc tccgaaggag aaggcgatgc ggttaccgac caaaccgaat tttccgcatc
     4441 cgcaacaaac cctctcccta gccctctccc acaggagagg gaacaaagtg cagccg
//
LOCUS       DAXIDM010000130         4184 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000130 DAXIDM010000000
VERSION     DAXIDM010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4184
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.130"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            225..1742
                     /locus_tag="ACFOAE_001847"
     CDS             225..1742
                     /locus_tag="ACFOAE_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="surface lipoprotein assembly modifier"
                     /protein_id="HFC6885270.1"
                     /translation="MLYFRYGFLVVWCAAGVSAAYGADAPAILDDKALLQVQRSVSDK
                     WAESDWKVENDAPRVVDGDFLLAHPKMLEHSLRDALNGNQADLIASLADLYAKLPDYD
                     AVLYGRARALLAKLAGRPAEAVARYRELHGENAADERILLDLAVAEFDDFRLKSAERH
                     FAEAAKLDLPAPVLENVGRFRKKTEGLTGWRFSGGISPAVNRNANNAAPQYCRQNGGR
                     QICSVSRAERAAGLNYEIEAEKLTALADNHYLLFRSNIGGTSYYFSKKSAYDDGFGRA
                     YLGWQYKNARQTAGILPFYQVQLSGSDGFDAKTKRVNNRRLPPYMLAHGVGVQLSHTY
                     RPNPGWQFSVALEHYRQRYREQDRAEYNNGRQDGFYVSSAKRLGESATVFGGWQFVRF
                     VPKRETVGGAVNNAAYRRNGVYAGWAQEWRQLGGLNSRVSASYARRNYKGVAAFSTEA
                     QRNREWNVSLALSHDKLSYKGIVPALNYRFGRTESNVPYAKRRNSEVFVSADWRF"
     gene            complement(1801..3681)
                     /locus_tag="ACFOAE_001848"
     CDS             complement(1801..3681)
                     /locus_tag="ACFOAE_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002227695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate-binding protein"
                     /protein_id="HFC6885271.1"
                     /translation="MPYFALFDDAVSGRAKRYQNHVESRFFRPEELDALDSALQKGWQ
                     KGLHSVLFADYGFGLPLTGVESERGGNLALHWFADCADTDAENWLARHSDGLPAGIST
                     PQSSVSEADYLDHIRQIHEAIRRGDTYQINYTTRLHLQAYGNPVSLYRRLRQPVPYAV
                     LSHLPDAEGQSAWTLCFSPELFLNIASDGTISTEPMKGTAPILGDGQDERRAAELQAD
                     PKNRAENVMIVDLLRNDLGKIAQTGKVCVPEPFKVSRFGSVWQMTSTIQAQALPHTSF
                     ADILRAAFPCGSITGAPKKMSMQIIESLETEARGLYTGSIGYLNPCSGGLGFEGTFNV
                     VIRTLSLKPVSASDGIVSGIGGPDSNAQARTAGQGGATPHPFDSNPPYRGVYGVGSGI
                     VIDSDPAAEYRECGWKARFLNELRPDFGIFETLRAENGRCTLLDRHLCRLKTSAQALN
                     LPLPDGCENQIKQYIADLPDGAFRIKALLASDGISLSRAVLNHLADKQRVIISPTILP
                     AQNYLRRFKTTHRALFDQAWQTAETQGAFDSLFFNSDGILLEGGRSNVFVKHRGQWLT
                     PSLDLDILNGIMRQAVLDEPQKYLQTNQVIETHITQKTLQEAEEIRLSNALRGVFAAA
                     LA"
BASE COUNT          860 a          945 c         1356 g         1023 t
ORIGIN      
        1 agtgaatcgg tttcgtacta tttgtactgt ctgcggcttc gtcgtcttgt cctgattttt
       61 gttaatccgc tataaatgtg aaatccgccc tttgaaaatc gggcggcggt tttttgcctg
      121 cccgctttca gacggcaaag ccggttttca cgggtttctg cctgtttttc ggatggtttg
      181 acgtgcttcg gcggcgtgtt tgccagaaag gtaaatgaca gggtatgttg tatttcagat
      241 acggtttttt ggttgtttgg tgtgcggcag gtgtttctgc cgcctatggg gcggatgcgc
      301 ccgcgatttt ggatgacaag gcattgttgc aggtgcagcg gtcggtgtcg gataagtggg
      361 cggaatcgga ttggaaagtt gaaaatgatg ccccgcgcgt ggttgacggg gattttttgt
      421 tggcgcatcc gaaaatgttg gaacatagtt tgcgcgacgc gctcaacggc aatcaggcgg
      481 atttaatcgc ttcgttggcg gatttgtatg ccaagctgcc ggattatgac gcggttttat
      541 acggcagggc gcgggctttg ctggcgaaat tggcgggaag gccggcggag gcggtggcgc
      601 ggtatcggga actgcacggg gaaaatgcgg cagacgagcg gattttgctg gatttggcgg
      661 tggcggagtt tgacgatttc cggctgaagt cggcagaaag gcattttgcg gaggcggcaa
      721 aattggattt gccggcgccg gttttggaaa atgtggggcg ttttcggaaa aaaacggagg
      781 ggctgacggg ctggcgtttt tcgggcggca tcagtccggc ggtcaataga aatgccaata
      841 atgccgcgcc gcagtattgc cggcaaaacg gaggccggca gatatgcagt gtcagccggg
      901 cggagcgggc ggcaggcttg aattatgaaa tcgaggcgga aaaactgacg gcgttggcag
      961 ataatcatta tttgttgttc cgttccaata tcggcggcac gagctattat ttcagtaaaa
     1021 aatcagctta tgacgacggg ttcggcaggg cgtatttggg ttggcagtat aaaaatgcac
     1081 ggcagacggc ggggattttg ccgttttatc aggtgcagtt gtcgggcagc gacggctttg
     1141 atgcgaaaac aaaacgggta aacaaccgcc gcctgccgcc gtatatgctg gcgcacggag
     1201 tcggcgtgca gttgtcccat acttaccgcc caaacccggg atggcaattt tcggtcgcgc
     1261 tggaacatta ccgccaacgc taccgcgaac aggatagggc ggaatacaat aacggcaggc
     1321 aggacgggtt ttatgtttcg tcggcaaaac gtttgggcga atcggcaact gtgttcggcg
     1381 gctggcagtt tgtgcggttt gtgccgaaac gcgaaacggt gggcggcgcg gtcaataatg
     1441 ccgcctaccg gcgcaacggt gtttatgccg gttgggcgca ggagtggcgg cagttgggcg
     1501 gtttgaacag tcgggtttcc gcgtcttatg cccgccgcaa ctataagggc gttgcggctt
     1561 tctcgacaga ggcgcaacgc aaccgcgaat ggaatgtctc gctggctttg agccacgaca
     1621 agttgtcgta caaaggtatc gtgcccgcgt tgaattatcg tttcggcagg acggaaagta
     1681 atgtgccgta tgcgaaacgc cgcaacagcg aggtgtttgt gtcggcggat tggcggtttt
     1741 gaatggtggg ataatgccgt ccgaactttg gaaacaggtt cggacggcat ttttgcgcgt
     1801 tcaggcaagg gcggcggcaa atacgccgcg cagggcgttg gagaggcgga tttcttcggc
     1861 ttcttgcagt gttttttgtg tgatgtgtgt ttcgattact tgatttgttt gcaaatattt
     1921 ttgcggttcg tccaatacgg cttggcgcat tatgccgttt aaaatgtcca aatctaaaga
     1981 gggcgtaagc cattgtccgc gatgtttgac gaacacgttg cttctgccgc cttcgagcag
     2041 gatgccgtct gaattgaaaa acaggctgtc gaacgcgcct tgtgtttcgg cggtttgcca
     2101 cgcttggtcg aagagggcgc ggtgggtggt tttgaagcgg cgcaggtagt tttgtgcggg
     2161 caggatggtc ggcgaaatga tgacgcgctg tttgtcagcc aaatggttta aaacggcgcg
     2221 ggacaggctg atgccgtctg aagcgagcag ggctttgatg cggaacgcgc cgtcgggcaa
     2281 gtcggcaatg tattgtttga tttgattttc gcagccgtcg ggcaggggca ggttgagggc
     2341 ttgggcggag gttttcagac ggcataggtg gcggtcgagc agggtgcagc gtccgttttc
     2401 cgcgcgcagg gtttcaaaaa tgccgaagtc ggggcgcaat tcgttgagga aacgggcttt
     2461 ccagccgcat tcgcgatatt cggcggcggg gtcgctgtcg atgacgatgc cggaaccgac
     2521 accgtacacg ccccgatacg gcggattgga gtcaaacgga tgcggcgttg ccccgccttg
     2581 ccctgccgtt cgggcttgcg cgtttgaatc cgggccgccg atgcctgaaa caatgccgtc
     2641 tgaagccgaa acgggtttga gcgataaggt gcggataacg acgttgaacg tgccttcaaa
     2701 ccccaagccg ccggaacacg ggttcaaata gccgatgctg cccgtataaa gtccgcgtgc
     2761 ttcggtttcg agcgattcga taatctgcat actcattttt ttgggcgcgc cggtgatgct
     2821 gccgcagggg aaggcggcgc ggaggatgtc ggcgaacgag gtgtgcggca gggcttgggc
     2881 ttggatggtg ctggtcatct gccaaacgct gccgaaacgt gatactttaa acggctcggg
     2941 cacgcatact ttgccggttt gggcgatttt gccgaggtcg ttgcgcagca aatcgacaat
     3001 catcacgttt tcggcgcggt ttttcgggtc ggcttgcaat tcggcggcgc ggcgttcgtc
     3061 ttgtccgtcg cccaaaatcg gcgcggtgcc tttcatcggt tcggtgctga tggtgccgtc
     3121 tgaagcgatg ttgaggaaga gttcgggcga gaaacaaagc gtccacgcgg attgcccttc
     3181 cgcatcgggc aggtgggaca aaacggcata ggggacgggc tggcgcaggc ggcggtagag
     3241 gctgacggga ttgccgtagg cttgcaggtg caggcgggtg gtgtagttga tttgataggt
     3301 gtcgccgcgc cggatggctt cgtggatttg gcggatatgg tcgaggtaat cggcttcgga
     3361 tacggaggat tgcggcgtgg aaatgccggc ggggaggccg tctgaatgtc gggcaagcca
     3421 gttttcggca tcggtgtcgg cgcagtcggc aaaccagtgc agggcaagat tgccgccgcg
     3481 ttcggactcg acccccgtca gcggcaaacc gaatccgtag tctgcaaaca acaccgaatg
     3541 cagccctttt tgccagccct tttgcagcgc gctgtccaaa gcatcgagtt cttcgggacg
     3601 gaaaaaacgg ctttccacat gattttgata gcgttttgcg cggccgctta cggcatcgtc
     3661 aaacagggcg aaataaggca tggcaattcg gggcaaatgt tttgattata cgctcttttt
     3721 acacatattt tcagacgatt cggcaaatat cggcaaaatg taattttatg tagagaaagt
     3781 ggggggcgaa ggtgtaaaat tgtgaaaaca aattccgatt tccaacctga aatacaataa
     3841 ggagaccttt atgacagacc accagctgca accgtttgaa aacgtagaat taggcgaaaa
     3901 gcaagaccag ctccaagtat agtggattaa caaaaaccag tacagcgttg cctcgcttta
     3961 gctcaaagag aacgattctc tcaggtgctg aagcaccaag tgaatcggtt ccgtactatt
     4021 tgtactgtct gcggctccgt cgccttgtcc tgatttttgt taatccacta taaagaccgt
     4081 cgggcatctg cagccgtcat tcccgcgcag gcgggaatct agtctgttcg gtttcagtta
     4141 ttttcgataa atgcctgttg cttttcattt ctagattccc actt
//
LOCUS       DAXIDM010000131         4120 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000131 DAXIDM010000000
VERSION     DAXIDM010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4120
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.131"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            43..675
                     /locus_tag="ACFOAE_001849"
     CDS             43..675
                     /locus_tag="ACFOAE_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFC6885272.1"
                     /translation="MENTNRVPEQARYDAERRQADEALAGVFPAVSIFGSARTPQNHA
                     DYAFACRLARRLSDSGIAVISGGGPGIMEAANKGAFAGKSVSVGLNIVLPHEQKPNPY
                     QDIALRFSRFAERKAVFFRYSQAYVVMPGGFGTLDELFEILTLVQTGKVPPRPIVLVG
                     KAFWSGLAEWINAQLLARGLISEGAVSLFAISDDEDEIVAYLSEHGLQTA"
     gene            747..2117
                     /gene="purB"
                     /locus_tag="ACFOAE_001850"
     CDS             747..2117
                     /gene="purB"
                     /locus_tag="ACFOAE_001850"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0006188 - IMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFC6885273.1"
                     /translation="MINPIASLSPLDGRYAQSVEALRPIFSEYGLMKARVKVELNWLK
                     ALAAEPEIAEVPPFSAETLAEIDTVIENFSLEDAAAVKAIEATTNHDVKAIEYWLKKR
                     FAEVPEVAAVSEFIHFACTSEDINNLSHALMLQEAREAVLLPKLAEIIEKLTAMAHDL
                     AAVPMMSRTHGQPATPTTLGKETANVVYRLQRQFKNLQAQEFLGKINGAVGNYNAHMV
                     AYPDVDWETHCRNFVEISLGLTFNPYTIQIEPHDYMAEFFQTLSRINTILIDFNRDVW
                     GYISLGYFKQKVKAGEVGSSTMPHKVNPIDFENSEGNLGMANAVLGFLSEKLPISRWQ
                     RDLTDSTVLRNMGVGVGYAVLGFAAHLRGLNKLEPNPAALAADLDATWELLAEPIQTV
                     MRRYGVANPYEKLKDLTRGKGGITPEVLKGFIGSLEIPVEAKAKLLELTPALYVGKAE
                     ALAKRI"
     gene            2198..4066
                     /locus_tag="ACFOAE_001851"
     CDS             2198..4066
                     /locus_tag="ACFOAE_001851"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002241050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFC6885274.1"
                     /translation="MQAVRYRPEIDGLRAVAVLSVIIFHLNNRWLPGGFLGVDIFFVI
                     SGFLITGIILSEIQNGSFSFRDFYTRRIKRIYPAFIAAVSLASVIASQIFLYEDFNQM
                     RKTVELSAVFLSNIYLGFQQGYFDLSADENPVLHIWSLAVEEQYYLLYPLLLIFCCKK
                     TKSLRVLCHISIILFLILTASSFLPSGFYTDILNQPNTYYLSTLRFPELLAGSLLAVY
                     GQTQNGRRQTANGKRQLLSSLCFGALLACLFVIDKHNPFIPGMTLLLPCLLTALLIRS
                     MQYGTLPTRILSASPIVFVGKISYSLYLYHWIFIAFTHYITGDKQLGLPAVSAVAALT
                     AGFSLLSYYLIEQPLRKRKMTFKKAFFCLYLAPSLILVGYNLYARGILKEEHLHPSSG
                     TPVAAENNFPETVLTLGDSHAGHLRGFLDYVGSREGWKAKILSLDSECLVWVDTTLAD
                     NPLCRKYRDEVEKAEAVFIAQFYDLRMGGQPVPRFEAQSFLIPGFQARFRETVKRIAA
                     VKPVYVFANNTSISRSPLREEKLKRFAANQYLRPIQAMGDIGKSNQAVFDLVKDIPNV
                     HWVDAQKYLPKNTVEIHGCYLYGDQDHLTYFGSYYMGREFHKHERLLKSSRDGALQ"
BASE COUNT          938 a         1118 c         1063 g         1001 t
ORIGIN      
        1 tttttgacgg tgtacaatcg ctgtttttga acggaggatg gaatggagaa tacaaaccgt
       61 gtgccggagc aggcacgtta tgatgccgaa cgcaggcagg cagacgaagc attggcgggc
      121 gtgtttccgg cagtcagtat cttcggcagc gcgcgcacgc cgcagaatca tgcggattat
      181 gcgttcgcct gccgtctggc gcggcggctg tcggattcgg gcattgccgt catttcgggc
      241 ggcgggccgg ggattatgga ggcggcaaac aagggcgcgt ttgcagggaa gtcggtttcg
      301 gtggggctga acatcgtttt gccgcacgag cagaaaccga atccgtatca ggacatcgcc
      361 ttgcggtttt cccgttttgc cgaacgcaag gcggtgtttt tccgctattc ccaagcatat
      421 gtcgtgatgc cgggcggctt cgggacgctg gacgaattgt ttgaaatcct gaccttggtg
      481 cagacgggca aagtgccgcc gcgtccgatt gttttggtcg gaaaggcgtt ttggtcgggc
      541 ttggcggagt ggataaacgc gcagcttttg gcgcgcggtc tgatttccga aggggcggtc
      601 tctttgtttg ccatatcgga cgatgaagac gaaatcgttg cgtatctgtc ggaacacggg
      661 cttcagacgg catagcgtcc tgagagtgat gtataattgc aaacaattta acaaattttg
      721 atgtcttttc cgaacaggat gccgatatga tcaaccccat cgcctcgctt tcccccctag
      781 acggccgtta tgcccaatcc gttgaagcat tgcgcccgat tttttcagag tacggcctga
      841 tgaaggcgcg cgtcaaagtc gaattaaact ggctcaaagc cctcgccgcc gagccggaga
      901 ttgccgaagt gccgcccttc agtgccgaaa cgcttgccga aatcgacacg gtgattgaaa
      961 acttctcact tgaagacgcg gccgccgtca aagccatcga agccaccacc aatcacgatg
     1021 tcaaagccat cgaatattgg ctgaaaaaac gttttgccga agtgccggaa gtcgccgccg
     1081 tgagcgagtt catccacttc gcctgcacca gcgaagacat caacaacctg tcccacgctt
     1141 taatgctgca agaagcgcgt gaggctgttt tgctgccgaa gctggccgaa atcatcgaaa
     1201 aactgaccgc tatggcgcac gatcttgccg ccgtcccgat gatgagccgc acccacggcc
     1261 agcccgccac gccgaccact ttgggcaaag aaaccgccaa tgtcgtgtac cgcctgcaac
     1321 gccagtttaa aaacctgcaa gcgcaagagt tcctcggcaa aatcaacggc gcggtcggca
     1381 actacaacgc ccatatggtc gcctatcctg atgtagattg ggaaacccac tgccgcaact
     1441 tcgtcgaaat cagcctcggc ctgaccttca acccctacac catccaaatc gaaccgcacg
     1501 actatatggc ggaattcttc caaaccctca gccgcatcaa cacgattctc atcgacttta
     1561 accgcgacgt ttggggttat atttcattgg gttacttcaa acaaaaagtc aaagcaggcg
     1621 aagtcggttc ttccaccatg ccgcacaaag tcaaccccat cgactttgaa aactccgaag
     1681 gcaacctcgg tatggcaaac gccgtattgg gctttttgtc cgaaaaactg ccgatttccc
     1741 gttggcagcg cgacctgacc gacagcaccg tcttacgcaa tatgggcgtg ggcgtgggct
     1801 atgccgtgtt gggtttcgcc gcacacctgc gcggtctgaa caagctcgaa cccaaccctg
     1861 ccgcgcttgc cgccgatttg gatgccactt gggaactgct cgccgagccg attcaaaccg
     1921 tgatgcgccg ttacggtgtc gccaatcctt acgaaaaact gaaagacctg acgcgcggca
     1981 aaggcggcat tacgcccgaa gtgctgaaag gctttatcgg atcgctggaa atccccgtcg
     2041 aagccaaagc aaaattgctt gagctgaccc ccgcactgta tgtgggcaag gctgaagcgt
     2101 tggcgaaacg gatttgagcg tttattgaaa ccgatgccgt ctgaacgcgc gttcagacgg
     2161 catttttaag ataacgggac atacgggggc gatatttatg caagctgtcc gatacaggcc
     2221 tgaaattgac ggattgcggg ccgttgccgt gctatccgtc attattttcc acctgaataa
     2281 ccgctggctg cccggagggt ttttgggggt ggacattttc tttgtcatct cgggattcct
     2341 cattaccggc atcattcttt ctgaaataca gaacggttct ttttctttcc gggattttta
     2401 tacccgcagg attaagcgga tttaccctgc ctttattgcg gccgtgtcgc tggcttcggt
     2461 gattgcctct caaatcttcc tttacgaaga tttcaaccaa atgcggaaaa ccgtggagct
     2521 ttctgcggtt ttcttgtcca atatttattt ggggtttcag caggggtatt tcgatttgag
     2581 tgccgacgag aaccccgtac tgcatatctg gtctttggcg gtagaggaac agtattacct
     2641 cctgtatcct cttttgctga tattttgctg caaaaaaaca aaatcgctac gggtgttgtg
     2701 ccacatcagc atcatcctgt ttttgatttt gactgcctca tcgtttttgc caagcgggtt
     2761 ttataccgac atcctcaacc aacccaatac ttattacctt tcgacactga ggtttcccga
     2821 gctgttggca ggttcgctgc tggcggttta cgggcaaacg caaaacggca gacggcaaac
     2881 agcaaatgga aaacggcagt tgctttcatc actctgcttc ggcgcattgc ttgcctgcct
     2941 gttcgtgatt gacaaacaca atccgtttat cccgggaatg accctgctcc ttccctgcct
     3001 gctgacggca ctgcttatcc ggagtatgca atacgggaca cttccgaccc gcatcctgtc
     3061 ggcaagcccc atcgtatttg tcggcaaaat ctcttattcc ctatacctgt accattggat
     3121 ttttattgcc ttcacccatt acattacagg cgacaaacag ctcggactgc ctgccgtatc
     3181 ggcggttgcc gcgttgacgg ccggattttc cctgttgagc tattatttga ttgaacagcc
     3241 gcttagaaaa cggaagatga ccttcaaaaa ggcatttttc tgcctctatc tcgccccgtc
     3301 cctgatactt gtcggttaca acctgtacgc aaggggtata ttgaaagagg aacatctcca
     3361 cccgtcgtcc ggtacgcccg ttgctgcgga aaataatttt ccggaaaccg tcctgaccct
     3421 cggcgactcg cacgccggac acctgcgggg ttttctggat tatgtcggca gccgggaagg
     3481 gtggaaagcc aaaatcctgt ccctcgattc ggagtgtttg gtttgggtgg atacgacact
     3541 ggcagacaac ccgttatgtc gaaaataccg ggatgaagtt gaaaaagccg aagccgtttt
     3601 cattgcccaa ttctatgatt tgaggatggg cggccagccc gtgccgagat ttgaagcgca
     3661 atccttccta atacccgggt tccaagcccg attcagggaa accgtcaaaa ggatagccgc
     3721 cgtcaaaccc gtctatgttt ttgcaaacaa cacatcaatc agccgttcgc ccctgaggga
     3781 ggaaaaattg aaaagatttg ccgcaaacca atatctccgc cccattcagg ctatgggcga
     3841 catcggcaag agcaatcagg cggtctttga tttggttaaa gatatcccca atgtgcattg
     3901 ggtggacgca cagaaatacc tgcctaaaaa cacggtcgaa atacacggct gctatcttta
     3961 cggcgaccaa gaccacctga cctatttcgg ttcttattat atggggcggg aatttcacaa
     4021 acacgaacgc ctgcttaaat cttctcgcga cggcgcattg cagtagcctg ccttgccgtc
     4081 cgatatcgtt tgtgccgccg tttgcctttc ggggcggcgg
//
LOCUS       DAXIDM010000132         4096 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000132 DAXIDM010000000
VERSION     DAXIDM010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4096
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.132"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..1148)
                     /locus_tag="ACFOAE_001852"
     CDS             complement(<1..1148)
                     /locus_tag="ACFOAE_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HFC6885275.1"
                     /translation="MYSNNAITNNRNNITLGAYRDAIISIFSDENVVRAIGTINSMYE
                     EYLTRSHKIDQKEFLREGERLSAKAREFQRTAEEAQKSLKEGIGRAASKFRGNSKEAF
                     VARKVQSDLQKALNASNYNKQQYARRAATALENASKSKVMAANLGKFTYGATVAMGTL
                     SMGSAWWKALDGEGNWSDVGLSSASFLGGLMGVQWGAALGVGAFGLLTGGAGWLVVGA
                     ILGGGAGAWWGSLGAEKAWRWFEDFLNLNRSDKYHVYDPLALDLDGDGIETVATKGFA
                     GALFDHRNQGIRTATGWVAADDGLLVRDLNGNGIIDNGAELFGDNTKLADGSFAKHGY
                     AALAELDSNGDNIINAADAAFQSLRVWQDLNQDGISQANELRTLEELG"
     gene            complement(1744..2154)
                     /locus_tag="ACFOAE_001853"
                     /pseudo
     CDS             complement(1744..2154)
                     /locus_tag="ACFOAE_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237155.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2204..2711)
                     /locus_tag="ACFOAE_001854"
                     /pseudo
     CDS             complement(2204..2711)
                     /locus_tag="ACFOAE_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247159.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3467..4096
                     /locus_tag="ACFOAE_001855"
                     /pseudo
     CDS             3467..4096
                     /locus_tag="ACFOAE_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611454.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
BASE COUNT         1324 a          863 c          664 g         1245 t
ORIGIN      
        1 atacccaatt cttcaagggt acgcaattca ttagcttggg aaatgccgtc ctggttgaga
       61 tcctgccata cacgcaggga ttggaatgcg gcgtctgccg cgttgatgat gttgtcgccg
      121 tttgaatcca attcggccaa agccgcgtag ccgtgtttgg caaaagagcc gtctgccagt
      181 ttggtgttgt cgccgaagag ttccgcaccg ttgtcgatga tgccgttgcc gttcaaatcg
      241 cgcacaagca gaccgtcatc ggcagcaacc caacctgtgg cggtgcggat gccttgattg
      301 cggtggtcga acaatgcacc tgcaaagcct ttggtggcaa cggtttctat accgtcgccg
      361 tctagatcta gggcgagggg gtcgtaaacg tggtatttgt cgctgcggtt aagatttaag
      421 aaatcctcaa accatctcca agctttttca gctcctaatg atccccacca agctcctgcg
      481 ccacctccaa gtatagctcc aactactagc caacctgcgc caccagtaag taaaccaaaa
      541 gccccaacac ccaaagccgc accccattgg acgcccatta gcccacccaa aaaagaagct
      601 gatgagagac caacatcact ccaatttcct tctccatcca aggctttcca ccaagcactt
      661 cccatactca aagttcccat ggcaacagtt gccccataag taaacttacc caaattcgct
      721 gccataactt ttgattttga agcattctct aacgctgttg ccgcacgtct tgcatattgc
      781 tgcttgttat agttgctagc attcaatgct ttttgcaaat cactttgtac ttttcttgca
      841 acaaatgcct cctttgaatt accacgaaat ttactagcag ctcttccaat tccttctttt
      901 aagctttttt gtgcctcttc tgctgtgcgt tggaattctc ttgccttagc agacagacgc
      961 tcaccctccc ttaaaaattc tttttgatct atcttgtgcg aacgggtcaa atattcttcg
     1021 tacattgagt taatcgtacc aatcgcccta accacatttt catcagaaaa tatggaaata
     1081 atagcatccc tatacgcacc tagtgtaata ttgtttctat tattagttat agcattattc
     1141 gaatacataa tagcacctcc aaatttagaa ctaaatacgt ttatattctc tgtgtaataa
     1201 tatcaaataa ttaattaatg gataagtaag tccgaaaaaa taacaactaa aataagcaat
     1261 atactgattc tctcctttat taattagata tattgaaaaa caaataaaaa ataaacagaa
     1321 aacattcatg tgaaaaagcc acctcatatt cttatttata agtttaaaat aactaggcat
     1381 tgtatattta aaaatcggca catccaacgg aaacaaacca cataaaaatt tttctttatt
     1441 ctttattaaa gacatagttt tattttttaa aattagtcca aataatatac taacaattac
     1501 tattaaaaca ataagcacag cgtaattttt tataaaattc attaaaataa taacgaaaat
     1561 actaaataga ttacatacta taaattgaaa tataaaatat tcagtattta atccattttc
     1621 aaccgcgagt tttttaaaat atccttgctc gaaaaaatta aaaaaatcca ttaatacttt
     1681 cctctcaaga aaactaattt tagtttagtt aagataaaat gcaatattac ctttattttc
     1741 tgcttttgaa gcattttcca aagctgtgac tgcttgtctt gcatattgtt gcttgttata
     1801 gttactagca tttaacttct tttgcaaatc actttgcatt tttcttgcaa caaatgcctc
     1861 cttcgaattg gcatgaaatt tactagcagc ccttccaatc ccttctttta aagccctttg
     1921 agttttttct gctgagtgct gaaaatcttt cgctttacta gacaaccgct caccatcact
     1981 caaaaatttt tgttgatcta ttttatgcga acgagttaaa tactccccat gcattgtgtt
     2041 aattgtaccg attgccctaa ccacattttc atcagagaaa atagttacaa tggcattatt
     2101 gaattcattt agtgtaatct tatttttttc atcattctta gaaccgggtt gcatgacaac
     2161 accttccatc aactaaaata ttatattatt aagagactac aacttagata cgtttataat
     2221 ctctggataa aaaaacgtaa taagtgtttg ctggataaca aagtccaaac caatagcaga
     2281 taaaataagg catccacccc ctttcttcat taaggatcag agatatcgag aaacaaatca
     2341 taactaaaca gaaaaaattt tggagataaa gccatttcat tcccctattc aagaatctgg
     2401 ccaagatagg tattttgtat actctagaaa agaaaggcat ttccaaggga aacatatcag
     2461 ataaaaactt ttgtttattt tttactatag atagaaccct atttctcaag ataaatccaa
     2521 atgcaatgcc aattatcatt attaataaac aaaggatagt ataactatgg ataaccttca
     2581 ttaaacaaaa agaagaaacg gcagataaat tacatacgat atagtggaat ataaaatatt
     2641 tacggtctaa accttgttca gttgcaattt ttttatactt accttgcgca aaaaaaatca
     2701 aagaaatcca ttaaactatc tttcacatta gaaatttaaa agctaaataa tacgacaaac
     2761 aatgtgaagt actattcatg gtttatttaa aaaataatac tattctgaac attatttaga
     2821 tacagaaatt aacaaattgg aactaaacaa gcttttaaat actttaattt tattggaaag
     2881 ctataaaagg aactatagtt tcacacacta attacttcct aatcacttct ttattaagag
     2941 gcacaaggga ttggggaggc tgtcttggag ataagcactg atgttctagg caaacccctc
     3001 catcttaaag ttaaaacaac cacaggcagc ctggaaatga tctatgatct atgcccatac
     3061 aaggacattc tagatagttt tccttgttgc ttcgtgtatc acacaagata gaattggcac
     3121 tctactcttt ccttaaaaaa ccgtcaagaa tggttatcaa tttttttaaa cttattcaaa
     3181 acaatattct tatacacatc tcaaacccgc tgaaataaag caaagtggtg gttcatagat
     3241 ggcaataccg atttcaaagc agcctgcact ttgacaacac acgagaaata cgggaagaac
     3301 agggcatcag catatatttc agcccgaagc cgtttcattc gtttaaaaaa ctgctttttt
     3361 cacaatttac ctttacaaag cctatacgta tccttacaat ttgttttgct gtttttggta
     3421 tatttttggg gctgtactac attagcagat atgttaccct cgaaatatga agataacaca
     3481 ctgcaaatta aagaaaaaag tacagaaaga actgctccgt ttttttgtgc tggaagttac
     3541 cgcccgttct gccgccgata ttttgggtat ccatcccaat tcggcagcac tgttctaccg
     3601 taaaatccgc acggttacca actatcattt ggccttggct gccgatgagg tttttgaggg
     3661 ccctgtcgag ccggacgaaa gcgatttcgg cggacggcgt aaaggcagac gtggtcgcgg
     3721 tgcggcagga aaagtggttg ttttcggcat tctgaaacgc aacagacggg tctataccgt
     3781 tgtggtggat aatgccaagt ctgaaacgtt actccctgtc atcaaaaaga aaatcatgcc
     3841 ggacagcatt gtttataccg atagtctgag caactgcgac aagttggacg tgagcggttt
     3901 tatccattac cgcatcaacc attccaagga atttgcagac cgtcaaaacc acattaacgg
     3961 cattgagaac ttttggaatc aggcaaaacg cgtcttgcgc aaatagaacg gaattgatcg
     4021 caaatctttc ccgctgttct tgaaagaatg cgaatttcga tttaacttcg gcacaccgtc
     4081 ccgacagcta aaaatt
//
LOCUS       DAXIDM010000133         4073 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000133 DAXIDM010000000
VERSION     DAXIDM010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4073
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.133"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..612
                     /locus_tag="ACFOAE_001856"
     CDS             <1..612
                     /locus_tag="ACFOAE_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC6885276.1"
                     /translation="LKIEKASAAVVDATIIQTAGSKQRQAIEVDEEGQVGGQTTPSKD
                     SDARWIKKNGLYKLGYKQHTRTDAEGYIEKLHITPANAHECKHLPPLLEGLPEGTTVY
                     ADKGYDSAENRQHLEERQLLDGIMRKACRNRPLTETQTKRNRYLSKTRYVVEQSFGTL
                     HRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPAAA"
     gene            complement(888..1091)
                     /locus_tag="ACFOAE_001857"
     CDS             complement(888..1091)
                     /locus_tag="ACFOAE_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFC6885277.1"
                     /translation="MELGYTPYNLRNRCKLIQAELAQIVGVKHYIQVGRWEAEPDTET
                     RRADMPLEKWRQFLDWTEKTNAV"
     gene            complement(1103..1384)
                     /locus_tag="ACFOAE_001858"
     CDS             complement(1103..1384)
                     /locus_tag="ACFOAE_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885278.1"
                     /translation="MNRAALFNRYPEWIIGQDGASRFITHCRYPRLIAKIHRQTDGEC
                     PGGHYRHSENGITLYDFIFFDGKPADEARFAAVLTETCRRAVKKICETK"
     gene            complement(1422..1625)
                     /locus_tag="ACFOAE_001859"
     CDS             complement(1422..1625)
                     /locus_tag="ACFOAE_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885279.1"
                     /translation="MNIIEQEMKHSSLRKVDVEIAKIIADAHKINAESVKIAQESRWY
                     PMMAATGLVTAIAAVLALIFKFA"
     gene            complement(1705..2277)
                     /locus_tag="ACFOAE_001860"
     CDS             complement(1705..2277)
                     /locus_tag="ACFOAE_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HFC6885280.1"
                     /translation="MGKPGKSSRPSALLSARWQDIDLTARLWHIPAADMKTKHPFTVP
                     LSDWAVEILRELHTQTGDNIHLFPGIRPRRKPAPHPDHISIKFAHNAIRRLGYDGSTP
                     GKSKHTMHGFRHLFTNISLTAGKDTLTTDLALGHISRAALQRAGFSSLHHYLTADSYR
                     LQERRELAEWYSRRHRQAYEAAAQNTCNKT"
     gene            complement(2252..2596)
                     /locus_tag="ACFOAE_001861"
                     /pseudo
     CDS             complement(2252..2596)
                     /locus_tag="ACFOAE_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701232.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(2589..2846)
                     /locus_tag="ACFOAE_001862"
                     /pseudo
     CDS             complement(2589..2846)
                     /locus_tag="ACFOAE_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237890.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2857..3177
                     /locus_tag="ACFOAE_001863"
     CDS             2857..3177
                     /locus_tag="ACFOAE_001863"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885281.1"
                     /translation="MLGVLDCYQKSQSCPNPKSHCCFVSDDIFLWHGSRPTFEISLDL
                     TGKKKETSSAKKFVMPCINFRHHRIEKETYLGNWNEQIAALAVKQNIDWCPSFDIENF
                     RQYE"
     gene            3170..3364
                     /locus_tag="ACFOAE_001864"
     CDS             3170..3364
                     /locus_tag="ACFOAE_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFC6885282.1"
                     /translation="MNNYYLYRNCSSDVLWVKRIQRQIDGSLLLISDNSTYPPMPLAL
                     AEHPDIQIIGQVVQVSKDLN"
     gene            3388..3948
                     /locus_tag="ACFOAE_001865"
     CDS             3388..3948
                     /locus_tag="ACFOAE_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885283.1"
                     /translation="MKILALLIAATCALSACGGQAEEQPASAQPQEQAQSELKTMPVS
                     YTDYQSVANKGLADQKTGLTLPEHVVPADNAEGKNLLHDFSDGLTLTVDTDKADKITA
                     VRVVWNTDAVPQKAEKLSKAAAALIAATAPGDRTLLRDTGDQIKMAIDSHNAQKEPTR
                     EWARGGIAYKVTVTNLPSVVLTAKAE"
BASE COUNT          938 a          972 c         1139 g         1024 t
ORIGIN      
        1 ttaaaaatag agaaagcatc cgccgctgtt gttgatgcca ccattattca gactgccggc
       61 agcaaacagc gtcaggccat agaagttgac gaagaaggac aagtcggcgg ccaaaccaca
      121 ccgagtaagg acagcgatgc ccgttggata aagaaaaacg gcctctacaa actcggttac
      181 aaacaacata cccgcaccga tgcggaaggc tatatcgaga aactgcacat cacccccgcc
      241 aatgcccatg agtgcaaaca cctgccgccg ttgttggaag ggttacccga aggtacgacc
      301 gtctatgccg acaaaggcta tgacagtgcg gaaaaccggc aacatctgga agagcgtcag
      361 ttgttagacg gcattatgcg caaagcctgc cgcaaccgtc cgctgacgga aacgcaaacc
      421 aaacgcaacc ggtatttgtc gaagacccgt tatgtggttg aacagagctt cggtacgctg
      481 caccgtaaat tccgctatgc gcgggcagcc tatttcggac tgattaaagt gagtgcgcaa
      541 agccatctga aggcgatgtg tttgaacctt ttgaaagccg ccaacaggct aagtgcgccc
      601 gctgccgcct aaaaggcagc acggatgcct gattatcagg tgtccgggga ggattaaggg
      661 ggtatttggg tagaattagg cggtatttgg ggcgaaaaca gccgaaaacc tgtgtttggg
      721 tttcggctgt cgggagggaa aggaattttg caaaggtctc agagtgagtt tattttgggg
      781 cggcggcagg tcgggggcaa gcggcgtggg gcttggttgt ggtttttagg tttgggggtg
      841 ggtaaaaaat gccgtacccg gcgggcaggc ttcgcactct gaaggtttca gacggcgttt
      901 gttttttctg tccaatcgag gaactgccgc catttttcca gcggcatatc ggcccgccgc
      961 gtttcggtat cgggttcggc ttcccagcgg cctacctgta tgtagtgctt caccccgacg
     1021 atttgcgcca actcggcctg tatcagtttg cagcggttgc gcaggttgta aggtgtgtag
     1081 ccgagttcca tgtcgttgcg gtttattttg tttcgcatat ttttttgact gcccggcggc
     1141 aggtttcggt aaggacggcg gcaaatcggg cttcgtctgc cggttttccg tcgaaaaaaa
     1201 taaaatcgta aagggtgatg ccgttttcgg aatggcggta atgcccgccc gggcattcgc
     1261 cgtctgtctg cctgtggatt ttggcaatca ggcggggata gcggcaatgg gtaatgaaac
     1321 ggcttgcgcc gtcttgcccg ataatccatt cggggtagcg gttgaatagt gcggctctgt
     1381 tcattttgtt cgggggataa agcctctcgc ggggcttgtg gtcaggcaaa tttgaatatc
     1441 agtgccaaca cggcggcgat ggcggtaacc agcccggtgg ccgccatcat gggataccat
     1501 cgggattctt gggctatttt tacggattcg gcgttgattt tgtgcgcgtc tgcaatgatt
     1561 ttggcgattt cgacatctac ttttctcaga ctggagtgtt tcatttcttg ttcgattatg
     1621 ttcatcgtac ttcctttcgt ttttggcggt tgccgccgct tgtcggatgg taggatgtct
     1681 gccatgtgta tatattgata ccttttaggt tttattgcaa gtgttttggg cggcggcttc
     1741 gtatgcttgg cggtggcggc ggctgtacca ttcggcgagt tcgcgccgct cttggaggcg
     1801 gtagctgtcg gcggtcaggt agtggtgcag gcttgagaag ccggcgcgtt ggagggcggc
     1861 gcggctgatg tggccgaggg cgaggtctgt tgtgagggtg tcttttccgg cggtcaggct
     1921 gatgttggtg aagaggtggc ggaatccgtg cattgtgtgt ttggatttgc cgggggtgct
     1981 gccgtcatag cccagtcgtc ggatggcgtt gtgggcgaat ttgatgctga tgtggtcggg
     2041 atggggggcg ggtttgcgcc gtgggcggat gccggggaaa aggtggatgt tgtcgccggt
     2101 ctgcgtgtgc agctctcgga gtatttctac cgcccagtcc gacagtggga cggtaaaggg
     2161 gtgtttggtc ttcatgtcgg cggcggggat gtgccataac cgggcggtga ggtcgatgtc
     2221 ttgccagcgg gcggaaagca gtgcggacgg acgggatgac ttccccggtt tccccatcaa
     2281 tccgcgccgc ctcgattttt ccgttggcgc gcagcatttc caccgcctgc cgcaccgaca
     2341 tcaaccgctt gccgttgcgc ctcatcgcct ccaccaaaac cgccgaaatc aatttggctt
     2401 cttccggttt aagctccgtc ttgcccgcat cgctgcgccg tttgcacgtc ggcttgacgc
     2461 tgaccgcctc cagcttgcgg tatagcgtgg caaggctgat gcccaattcc tgcgcctgct
     2521 gcttaagata tgcagagcgt gcgccgcgtt ccattgcttc cgcctgattc tcgactgcct
     2581 taagacgctc aatcattgcc ggattcatcg ccttctcccg tttcaccgcc caaccattcc
     2641 ggcacattgt ctgtcggtgc ttcagtcggc agggcatagc tttcgcgcag ttgctcgcag
     2701 tccaaaataa tttgattgag cgtgccgacc atctttgcct gatggctgat ctcgtgtgcc
     2761 tcactgtgcg cattaagttg gtcgaacaaa tctttcaaac ggctcacttg actgcggata
     2821 ccgacctcaa ggcttgttaa ctgcatcatt tatgatttgt taggggtttt agactgctat
     2881 caaaaatcac agtcctgtcc caaccctaaa agccactgtt gctttgtttc agacgacatt
     2941 tttctatggc atggatcaag accaacgttt gaaatcagtc ttgatctaac tggaaagaaa
     3001 aaagaaacat cctctgcaaa gaaatttgtg atgccttgta ttaatttccg tcaccatagg
     3061 attgaaaaag aaacctactt aggaaattgg aatgaacaaa ttgccgcatt ggcagtaaaa
     3121 caaaatatag attggtgtcc aagttttgat attgagaatt ttagacagta tgaataatta
     3181 ctatctatat aggaattgca gcagcgatgt gttatgggtc aaacgtatcc aacgccaaat
     3241 cgacggcagc ctactcttga tttctgacaa ttcaacctat ccacccatgc ccttggcact
     3301 ggcggaacac cccgatattc aaatcatcgg gcaggtagtg caggtatcaa aagacttgaa
     3361 ctagacacaa tcaaaaaggg aaatagaatg aaaatactcg ctttattaat tgccgctacc
     3421 tgtgctttat ctgcgtgtgg cggccaagct gaagaacaac cggcatctgc ccaacctcaa
     3481 gagcaggcac aatccgaatt aaaaaccatg ccggtaagct ataccgacta tcaatcagta
     3541 gccaataaag ggcttgccga ccaaaaaact ggtctgaccc ttccagaaca tgttgttcct
     3601 gccgacaatg cggaagggaa gaatctgctg catgactttt cagacggcct cacattaacc
     3661 gttgataccg ataaagccga caaaattact gccgtccgag tagtttggaa tacagatgca
     3721 gtgcctcaaa aagcggaaaa actgtccaaa gccgccgcag ccttgattgc ggcaaccgcc
     3781 ccaggagacc gcacactgct gcgtgatacc ggcgaccaaa tcaaaatggc aattgacagc
     3841 cataatgcgc aaaaagagcc aacccgagaa tgggcgcgtg gtgggattgc ttataaagtc
     3901 actgttacta atttgccgag cgtggttttg acagcaaaag ctgaataacc tgcattacag
     3961 ccacaattag gagcagacgg agatgatgtt tatagagcct gctgagaata aataactgat
     4021 aaaaaagctg tctgaaaagg tttcggatag ttaggatagc tatctatttt taa
//
LOCUS       DAXIDM010000134         4068 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000134 DAXIDM010000000
VERSION     DAXIDM010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.134"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(119..775)
                     /locus_tag="ACFOAE_001866"
     CDS             complement(119..775)
                     /locus_tag="ACFOAE_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b/b6 domain-containing protein"
                     /protein_id="HFC6885284.1"
                     /translation="MKNKTKVWDFPTRLFHWLLAASLPFMWYSAKTGGDMLQWHTRVG
                     LLILFLLIFRLCWGIWGSDTARFSHFVRGWSGIRDYLKNGIPEHIQPGHNPLGALMVV
                     ALLAAVSFQVGTGLFAADENTFSTNGYLNHLVSEHTGSLMRKIHLNFFKLLAVFSAIH
                     IAAVAAYRLFKKKNLVFPMITGFKYIEGKTSIHFAGKAALAAALSVVALAAAAILLLS
                     "
     gene            840..1730
                     /locus_tag="ACFOAE_001867"
     CDS             840..1730
                     /locus_tag="ACFOAE_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFC6885285.1"
                     /translation="MFPVFHLSGESRRRMLQTALRFPYVFKARAEDSHKGTFGTLAVV
                     GGSAGMSGAPVLAASAAMYLGCGKVWAGFNQETLPFAVIAGFPEIMLDTADGLSKRQD
                     INAWVVGCGLGTGRAAVGTLAGILTEHTDKPVLLDADALNILSTDAETRNLARGCKNL
                     ILTPHPAEAARLLGTTVAQVQADRTAAVRKIGAIFGATVVLKGHKTLVAASDTEIYVN
                     ESGNAGLATAGSGDVLGGIIGSLLAQGVPVFEAACAGAWLHGAAADVIKESAGIAAGL
                     LAGEIAPAARWLRNRITESM"
     gene            2000..3811
                     /gene="typA"
                     /locus_tag="ACFOAE_001868"
     CDS             2000..3811
                     /gene="typA"
                     /locus_tag="ACFOAE_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFC6885286.1"
                     /translation="MKQIRNIAIIAHVDHGKTTLVDQLLRQSGTFRANQQVDERVMDS
                     NDLEKERGITILAKNTAIDYEGYHINIVDTPGHADFGGEVERVLGMVDCVVLLVDAQE
                     GPMPQTRFVTKKALALGLKPIVVINKIDKPSARPSWVIDQTFELFDNLGATDEQLDFP
                     IVYASGLSGFAKLEETDESNDMRPLFDTILKYTPAPSGSADEPLQLQISQLDYDNYTG
                     RLGIGRILNGRIKPGQVVAVMNHEQQIAQGRINQLLGFKGLERVPLEEAEAGDIVIIS
                     GIEDIGIGVTITDKENPKGLPMLSVDEPTLTMDFMVNTSPLAGTEGKFVTSRQIRDRL
                     QKELLTNVALRVEDTADADVFRVSGRGELHLTILLENMRREGYELAVGKPRVVYRDID
                     GQKCEPYENLTVDVPDDNQGAVMEELGRRRGELTNMESDGNGRTRLEYHIPARGLIGF
                     QGEFMTLTRGVGLMSHVFDDYAPVKPDMPGRHNGVLVSQEQGEAVAYALWNLEDRGRM
                     FVSPNDKIYEGMIIGIHSRDNDLVVNPLKGKKLTNVRASGTDEAVRLTTPIKLTLEGA
                     VEFIDDDELVEITPQSIRLRKRYLSELERRRHFKKLD"
     gene            complement(3823..>4068)
                     /locus_tag="ACFOAE_001869"
     CDS             complement(3823..>4068)
                     /locus_tag="ACFOAE_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885287.1"
                     /translation="LPKLVRTQKAYSFKRHCSTCCREAEPDTETRRGDIPLEKWRQFL
                     DWVGKTPSETASRSRKARPNKKCRLKFFRRHRVSFKH"
BASE COUNT          976 a         1064 c         1175 g          853 t
ORIGIN      
        1 aaaacggttt gggacggaaa aacggcctga agccgtttcg ggcattcaga ccgtttgcgc
       61 ggagagggga tgccgtccga agggcgaaaa gggcttcaga cggcattgat gtcgggtttc
      121 aggacaggag caggatggcg gctgcggcaa gcgcgacaac cgataatgcg gcggcaagcg
      181 cggctttgcc ggcaaagtgt atggaagttt tgccttcgat atatttgaag ccggttatca
      241 tcgggaagac gaggtttttc tttttgaata ggcggtatgc agcgacggcg gcgatatgga
      301 tggcggaaaa aacggcgagc agcttgaaaa agttgaggtg gattttccgc atcaggctgc
      361 ccgtatgctc ggaaaccaaa tggttgaggt agccgttggt gctgaaggtg ttttcatcgg
      421 cggcaaaaag ccccgtgccg acttgaaatg agacggcggc caaaagcgcg acgaccatca
      481 gtgcgcccaa ggggttgtgt ccgggctgga tatgttcggg aataccgttt ttcagataat
      541 ccctgatacc cgaccatccg cggacgaaat gggaaaaacg ggcggtatca ctgccccaaa
      601 tgccccagca gaggcggaat atgagcagga aaaggataag cagcccgacg cgcgtgtgcc
      661 attgcagcat atcgccgccg gttttcgcgc tataccacat aaagggtagg gatgcggcaa
      721 gcagccaatg gaaaaggcgg gtggggaagt cccagacttt ggttttgttt ttcataatcg
      781 gtttccggcg gtagaatcgg tttgttttcg agccttaatt ttaaccgatt ggaggggcaa
      841 tgtttcccgt ttttcatctt tcaggcgaga gccgccgccg gatgcttcag acggcattgc
      901 gttttcccta tgttttcaaa gcccgtgcgg aagattcgca caaagggact ttcggcacgc
      961 tcgccgtagt cggcggatcg gcagggatga gcggtgcgcc cgtattggcg gcatcggcgg
     1021 cgatgtatct cggctgcggc aaggtgtggg cgggtttcaa tcaggaaacg cttccgtttg
     1081 ccgtcattgc cggttttccc gagattatgc tggatacggc agacggtttg agcaagcgtc
     1141 aagatataaa cgcctgggtt gtcggttgtg gattgggtac aggtagggcg gcggtcggaa
     1201 cgcttgccgg aattttgacg gaacacacgg acaagcccgt ccttttggat gcggacgcgc
     1261 tgaacatatt atcaaccgat gccgaaaccc gaaatctggc acgcgggtgt aaaaacctga
     1321 ttttaacgcc acaccccgcc gaagccgcgc gcctgcttgg aacgacggtt gcacaggttc
     1381 aggcggatcg gacggcggca gtgaggaaga taggggcaat tttcggcgca accgtggttt
     1441 taaaggggca caaaacattg gttgccgcgt ccgatacgga aatctatgtc aacgaaagtg
     1501 gcaacgcggg attggcaacg gcgggcagtg gcgacgtatt gggcggcatc atcggcagtc
     1561 tgctcgcaca gggcgtgccg gtttttgaag ccgcctgcgc gggcgcgtgg ctgcacggcg
     1621 cggcggcgga tgtcataaaa gaatcggcag gcattgcggc agggctgttg gctggcgaaa
     1681 tcgccccggc ggcaaggtgg ctgcgtaacc ggataactga aagtatgtaa gaagatatag
     1741 tggattaaca aaaaccagta cggcgttgcc tcgccttagc tcaaagagaa cgattctcta
     1801 aggtgctgaa gcactaagtg aatcggttcc gtactatccg tactgtctgc ggcttcgccg
     1861 ccttgtcctg atttttgtta atccactata ccgtctgaaa ggcaagggct tcagacggca
     1921 tcttcatttc ccaaatactg tccggtaaag cgtggtataa tgcgcagtta tctcttacag
     1981 tttttgaaaa acattaatta tgaaacaaat ccgcaacatc gccatcatcg cccacgtcga
     2041 ccacggcaaa accacattgg tcgaccaact gctgcgccaa tccggcacat tccgcgccaa
     2101 ccagcaggtt gacgagcgcg tgatggacag caacgacctc gaaaaagaac gcggcatcac
     2161 catcctcgcc aaaaacaccg ccatcgatta cgaaggctac cacatcaata tcgtcgatac
     2221 gccgggacac gccgacttcg gcggcgaagt agagcgcgtt ttggggatgg tggactgcgt
     2281 cgtcttgttg gtggatgcgc aagaaggtcc gatgccgcaa acccgtttcg tgaccaaaaa
     2341 agccttggct ttggggctga aaccgattgt cgtcatcaac aaaatcgata aaccgtccgc
     2401 ccgtccgagc tgggtcatcg accaaacttt cgaactcttc gacaacttgg gcgcaactga
     2461 cgaacagttg gacttcccga ttgtttacgc ttcaggtttg agcggctttg ccaagctgga
     2521 agaaaccgac gagagcaacg acatgcgtcc gctgttcgac accatcctaa aatacacgcc
     2581 cgcaccgagc ggcagcgcgg acgagccgct gcaactgcaa atctcccaac tcgactacga
     2641 taactacacc ggccgcctcg gcatcggtcg tatcttgaac ggacgtatca agcccggtca
     2701 agttgttgcc gtgatgaacc acgagcagca aatcgcccaa ggccgcatca accagctttt
     2761 gggtttcaaa ggcttggaac gcgtgccgct tgaagaagcc gaagcaggcg acatcgtgat
     2821 tatttccggt atcgaagaca tcggtatcgg cgtaaccatc accgacaagg aaaatcccaa
     2881 aggtctgccg atgttgagcg tagacgaacc gacgctgacc atggacttta tggtgaacac
     2941 cagcccactc gcgggtactg aaggcaaatt cgtaaccagc cgccaaatcc gcgaccgcct
     3001 gcaaaaagaa ttgctgacca acgttgccct gcgcgtggaa gataccgccg atgccgacgt
     3061 gttccgcgta tccgggcgcg gcgaactgca cctgaccatt ttgttggaaa atatgcgccg
     3121 cgaaggctac gaactcgccg tcggcaagcc gcgcgtcgtg taccgcgaca tcgacggtca
     3181 aaaatgcgaa ccttatgaaa acctgaccgt ggacgtaccc gacgacaacc aaggcgcggt
     3241 aatggaagaa ctcggccgcc gccgtggcga actgaccaat atggaaagcg atggcaacgg
     3301 acgcacccgc ctcgaatacc atattccagc gcgcggcttg atcggtttcc aaggcgaatt
     3361 tatgaccctg acgcgcgggg tcgggctgat gagccacgtg ttcgacgatt acgcgcccgt
     3421 caaacccgat atgcccggcc gccacaacgg cgtgctggtg tcccaagagc agggcgaggc
     3481 agtcgcttac gccttgtgga atctggaaga ccgcggccgt atgttcgtat cgcccaacga
     3541 caaaatctac gaaggtatga ttatcggtat ccacagtcgc gacaacgatt tggtggtcaa
     3601 cccgctcaaa ggcaaaaaac ttaccaacgt ccgtgccagc ggtaccgacg aagccgttcg
     3661 cctgaccacg ccgattaaac tgacgctgga aggtgcggtt gagtttatcg acgatgacga
     3721 actcgttgaa atcacgccgc aatccatccg tctgcgcaag cgttacttga gcgaattgga
     3781 acgccgccgc cactttaaaa agctggattg atgtttactg gattaatgtt taaatgatac
     3841 gcgatgccgt ctgaaaaatt tcagacggca ttttttattc ggacgggctt tgcggcttct
     3901 tgaagctgtt tcagacggcg tttttcctac ccaatcaaga aactgccgcc atttttccag
     3961 cggtatatcg ccccgtcgcg tttcggtatc gggttcggct tcccggcagc atgtcgaaca
     4021 atgccgtttg aaggaatacg ccttttgagt ccttacaagc ttaggaag
//
LOCUS       DAXIDM010000135         4042 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000135 DAXIDM010000000
VERSION     DAXIDM010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4042
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.135"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..187
                     /locus_tag="ACFOAE_001870"
     CDS             <1..187
                     /locus_tag="ACFOAE_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885288.1"
                     /translation="NQYLSKTRYVVEQSFGTLHRKFCYVRAAYFGLIKVSAQSHLKAM
                     CLNLLKAANRLSAPAAA"
     gene            287..514
                     /locus_tag="ACFOAE_001871"
     CDS             287..514
                     /locus_tag="ACFOAE_001871"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885289.1"
                     /translation="MFGFRLSGGKGILQRSRALIAAKIDQAEISDSEKSWLKKELGKI
                     KDTALSTLTENAINAIPAATLITLLKKFVGL"
     gene            complement(511..1017)
                     /locus_tag="ACFOAE_001872"
     CDS             complement(511..1017)
                     /locus_tag="ACFOAE_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1804 family protein"
                     /protein_id="HFC6885290.1"
                     /translation="MAHPQEIREKLRRLYVSGEQTLETAALMCEIPQTTARAWKRADK
                     EKGDDWDKMRAAYTLAGGGIEDLSRAMLAGFMVQYNSTMTMLQDSSTEDLPPSDRAKL
                     LASLADAFTKTVSANARVMPETSKLATALELIEFLMAFVQEKHPKHLPAFVEVLEPFG
                     AEVEKKFG"
     gene            complement(1020..1217)
                     /locus_tag="ACFOAE_001873"
     CDS             complement(1020..1217)
                     /locus_tag="ACFOAE_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885291.1"
                     /translation="MSDPILEALARIENKTDQTLKNQKEMQAEIAQIRQDTKRTAITF
                     GALGGGVITVGWELLKAKMGL"
     gene            complement(1214..1480)
                     /locus_tag="ACFOAE_001874"
     CDS             complement(1214..1480)
                     /locus_tag="ACFOAE_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885292.1"
                     /translation="MDFEFGFRTLWPIATAAFWFWVNGISGRLKEADKRIDDLKEELH
                     AVKLSYHTKQDAKADRDNIAASLGRIENKLEKVNEKLDRKADKS"
     gene            complement(1492..1830)
                     /locus_tag="ACFOAE_001875"
     CDS             complement(1492..1830)
                     /locus_tag="ACFOAE_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885293.1"
                     /translation="MTYRELVERQLAVRHADLELGLSRARKQEPFVIHVSDLLDKAGI
                     EYAVRMDKDFQTTFHLEYPITNYDTFKRAVWQTLGAYYCVCNDGDGLEIASNRPDGYA
                     VRIVFGDVPV"
     gene            complement(1827..2045)
                     /locus_tag="ACFOAE_001876"
     CDS             complement(1827..2045)
                     /locus_tag="ACFOAE_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885294.1"
                     /translation="MNEYTFSYRFNGKSWSLSIWADNPEEARAKFRAARENAHYDGEV
                     VAKVYTFVNISWVKKLYKRTKYLMGIKE"
     gene            2058..2228
                     /locus_tag="ACFOAE_001877"
     CDS             2058..2228
                     /locus_tag="ACFOAE_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HFC6885295.1"
                     /translation="MYFEIYKDAKGEYRWRLKAANHEIIAQGEGYTSKQNCQHAVDLL
                     KSTTAATPVKEV"
     gene            complement(2273..2578)
                     /locus_tag="ACFOAE_001878"
     CDS             complement(2273..2578)
                     /locus_tag="ACFOAE_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002245357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885296.1"
                     /translation="MSLLKTVKMQAAVVLTALAITACSSTSAPSATEIKVVEKAVMPT
                     PPAALMVAPVRPNPPKDGKTVTLLEHAAEFGGYVAELENQNQAWRDWAGNHSRKVGN"
     gene            complement(2475..2894)
                     /locus_tag="ACFOAE_001879"
     CDS             complement(2475..2894)
                     /locus_tag="ACFOAE_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885297.1"
                     /translation="MNLVKLLANNWQPIAIIALVGTLLAVSHHQGYKSAFAKQQVVIE
                     KMKRDKAQAMLLSAQNYARELEQARAEAKKYEVKAHAVGMALAKKQAEVSRLKTENKK
                     EIENVLTQDRKNAGGGCIDGFGHHGLQLYKRALGYGN"
     gene            complement(2866..3102)
                     /locus_tag="ACFOAE_001880"
     CDS             complement(2866..3102)
                     /locus_tag="ACFOAE_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885298.1"
                     /translation="MRILDIFKNPATGNVSHSKLWANVACAAGTVKFVMLPDPSAEIW
                     AVYLGIVGGYAVARSLVSVKRQEVENESRETAGE"
     gene            complement(3105..3269)
                     /locus_tag="ACFOAE_001881"
     CDS             complement(3105..3269)
                     /locus_tag="ACFOAE_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003751173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885299.1"
                     /translation="MGQVAFYEKMIGLWSAKSREASEQADLAAFEFAEGELANYQEML
                     KRHLQTKSVE"
     gene            complement(3272..3478)
                     /locus_tag="ACFOAE_001882"
     CDS             complement(3272..3478)
                     /locus_tag="ACFOAE_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885300.1"
                     /translation="MNIIGKLKEAASYFLTKLIGENPSNEQVNRALIQMPNVRPIHTY
                     PRPNLRNSGVAAAKRAARKRKNRR"
     gene            complement(3475..4017)
                     /locus_tag="ACFOAE_001883"
     CDS             complement(3475..4017)
                     /locus_tag="ACFOAE_001883"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012221570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFC6885301.1"
                     /translation="MGKTVTLTAGHSNTDPGAVNGSDREADLAQDMRNIVAAILRDDY
                     GLTVKTDGTGKGNMPLREAVKLIRGSDVAIEFHTNSAAGKAATGIEALSTVKNKRWCQ
                     VLSKAVAKKTGWKLRGEDGFKPDNAGHHSRLAYAQAGGIVEPFFISNDTDLALFKTTK
                     WGICRAIADAIAMKLGAARV"
BASE COUNT          932 a         1129 c          929 g         1052 t
ORIGIN      
        1 taaccagtat ttgtcgaaga cccgttatgt ggtcgaacaa agcttcggta cgctgcaccg
       61 taagttctgc tatgttcggg cagcctattt cggactgatt aaagtgagtg ctcaaagcca
      121 cctgaaagcg atgtgtttga acctgttgaa agcggccaac aggttaagtg cgcccgctgc
      181 cgcctaaaag gcggcccgga tgcctgatta tcgggtatcc ggggaggatt aagggggtat
      241 ttgggtagaa ttaggaggta tttggggcga aaacagccga aaacctgtgt ttgggtttcg
      301 gctgtcggga gggaaaggaa ttttgcaaag gtctcgggct ttaattgcgg caaaaataga
      361 ccaagcggag atttctgatt cagaaaaaag ctggttgaaa aaagaattag ggaaaatcaa
      421 ggacactgca ttaagtacgc ttacggaaaa tgcaattaat gctatccctg ccgccaccct
      481 cattactctt ttaaaaaaat ttgttggcct ctaaccaaac ttcttctcca cttccgcccc
      541 aaacggctcc aatacctcca caaaggcagg caaatgtttg ggatgttttt cttgcacaaa
      601 cgccatcaag aactcaatca attccaaagc cgtcgccagt tttgacgttt ccggcatcac
      661 acgcgcattg gccgatacgg ttttcgtaaa cgcatcggcc aggctggcca acagcttggc
      721 gcggtcggac gggggcaaat cttcggtact cgaatcctgc agcatcgtca tcgtgctgtt
      781 gtactgcacc ataaaaccgg ccaacatcgc acggctcaag tcctcaatac cgccgccggc
      841 caaagtgtag gcggcgcgca tcttatccca gtcgtcgcct ttttccttat ccgcacgttt
      901 ccacgcacgc gcagtggtct gcgggatttc gcacatcaag gccgccgttt ccaaagtttg
      961 ctcgccgctc acatagagcc ggcgtaactt ttcacggatt tcttgcgggt gagccataat
     1021 tacagtccca ttttcgcttt aagcaattcc cagccgaccg taatcacgcc gccgcccagt
     1081 gcgccgaatg taatggccgt gcgtttcgtg tcttggcgga tttgcgcaat ttccgcctgc
     1141 atttctttct gatttttcag cgtttgatca gtcttgtttt caatacgcgc caaggcttct
     1201 aaaatcgggt cgctcatgat ttgtctgctt tcctgtccag tttttcgttt actttttcca
     1261 acttgttttc gatgcgtccc aacgaagccg caatattgtc gcggtctgcc ttggcatctt
     1321 gcttggtgtg ataagagagc ttgaccgcgt gcagctcctc tttcaggtcg tcgatacgct
     1381 tgtccgcttc tttcagacgg cctgaaatac cgttgaccca aaaccaaaat gccgccgtcg
     1441 caatcggcca cagggttctg aaaccaaatt caaagtccat ttaaaacccc tttaaaccgg
     1501 cacatcgccg aatacgatac ggacggcgta accgtcaggg cgattgctgg caatctccag
     1561 tccatcacca tcattacaaa cacagtaata cgcccccaaa gtttgccaaa ccgcacgttt
     1621 aaaggtgtca tagttcgtaa ttggatattc aaggtgaaac gtcgtctgaa aatccttatc
     1681 catgcgtacc gcgtactcaa tgcctgcctt atccaacaga tcggaaacat gaatgacaaa
     1741 cggctcttgc ttgcgtgcgc ggcttaagcc caattccaaa tcggcatggc gcacagccaa
     1801 ctgacgttca actaattcac ggtaggtcat tctttgatac ccattaaata ttttgtccgc
     1861 ttgtacaatt tcttaaccca cgaaatattt acaaatgtat aaacctttgc tacaacttcg
     1921 ccgtcatagt gcgcattttc tcgtgcagcc cgaaatttcg ccctggcttc ttcagggttg
     1981 tccgcccaaa tactcaatga ccaggacttg ccgttaaagc ggtaagaaaa cgtgtactca
     2041 ttcataggag aaaccttatg tattttgaaa tctataaaga cgcaaaaggc gaataccgtt
     2101 ggcgtttgaa agcagccaac catgaaatca tcgctcaggg cgaaggctac accagcaagc
     2161 aaaactgtca gcacgcagtc gatttgctga aaagcactac cgccgctacc cctgtaaaag
     2221 aggtataaaa tccgctttca ccctcagccc gcgccctacg cgggcttttt tgtcagtttc
     2281 cgactttgcg ggagtgattg cccgcccagt cgcgccaagc ctgattttgg ttttcaagtt
     2341 cggcaacata gccgccaaac tcggcggcgt gttccaacag cgttactgtc ttgccgtctt
     2401 tcggcggatt cgggcgtacc ggcgcgacca tcaatgcggc aggcggtgtc ggcatgaccg
     2461 ccttttcgac aaccttaatt tccgtagccg agggcgcgct tgtagagctg caagccgtga
     2521 tggccaaagc cgtcaataca accgccgcct gcatttttac ggtcttgagt aaggacattt
     2581 tcgatttcct ttttattttc cgttttcaga cggctgactt ccgcctgttt tttcgccaaa
     2641 gccatgccga cggcgtgcgc cttgacttca tattttttcg cttccgcgcg cgcctgttcc
     2701 agctcgcgtg catagttttg agccgacaac agcatggctt gcgccttgtc gcgcttcatt
     2761 ttctcaatga ccacctgctg cttcgcaaac gccgacttat agccttgatg gtgcgacacc
     2821 gccaagagcg tgccgacaag cgcgatgatg gcaatcggtt gccagttatt cgccagcagt
     2881 ttcacgagat tcattctcga cctcctgacg tttgacgctg accaacgaac gcgccaccgc
     2941 atagccgccg acaatgccca aatacaccgc ccaaatctcc gccgacgggt cgggcagcat
     3001 cacaaactta accgtccccg ccgcgcaggc aacgtttgcc cacagtttcg agtgcgacac
     3061 attgcctgtc gctgggtttt taaaaatatc caaaatacgc attgctattc cacacttttg
     3121 gtttgcaggt gccgtttcag catttcctga taattggcca gttcgccctc cgcaaattca
     3181 aacgccgcca agtctgcctg ttcgcttgcc tcacggcttt tggccgacca cagcccaatc
     3241 atcttttcgt aaaacgcaac ctgtcccatg attaacgacg attcttgcgt ttgcgcgccg
     3301 cgcgtttcgc ggctgccacg cctgagtttc ttaaatttgg gcgtggatag gtgtgtatcg
     3361 gacgaacatt tggcatctgt ataagtgcgc ggtttacctg ctcattacta ggattttctc
     3421 caatcaattt tgtaagaaaa taggaagcag cttctttcaa tttaccaata atattcatac
     3481 tcttgccgcc cccaatttca tcgcaatcgc gtccgcaatc gcgcggcaga tgccccattt
     3541 ggtcgtctta aacaaggcca aatcagtgtc gttgctgatg aaaaaaggct caacaatgcc
     3601 gccagcctgc gcataagcca ggcgcgaatg atggcccgca ttgtcgggtt taaagccgtc
     3661 ttcgccgcgc agtttccagc cggttttctt ggcaacagct ttgctcaaca cctgacacca
     3721 gcgtttgttt ttaacggtac tcaacgcctc aatgcccgta gctgctttac cggccgccga
     3781 gttggtatgg aactcaatcg ccacatccga gccgcgaatc agttttacag cttcacgcag
     3841 cggcatattg cctttgcctg tgccgtcggt tttaacagtc aaaccgtagt catcgcgcaa
     3901 aatagcagcc acgatgttgc gcatatcctg cgccaagtcc gcctcacggt cgctgccgtt
     3961 gaccgcaccc gggtcggtgt tgctgtgtcc agcggttaag gttacggttt tgcccattca
     4021 tcatctccaa aaaatattga tt
//
LOCUS       DAXIDM010000136         4028 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000136 DAXIDM010000000
VERSION     DAXIDM010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 4028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4028
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.136"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(92..1342)
                     /gene="glyA"
                     /locus_tag="ACFOAE_001884"
     CDS             complement(92..1342)
                     /gene="glyA"
                     /locus_tag="ACFOAE_001884"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004520001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFC6885302.1"
                     /translation="MFSKSVTLAQYDPDLAAAIAQEDQRQQDHVELIASENYVSCAVM
                     EAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRVKKLFGAQYANVQPHSGSQAN
                     QAVYASVLKPGDTILGMSLAHGGHLTHGASVNISGKLYNAVTYGLDENEVLDYAEVER
                     LALEHKPKMIVAGASAYALQIDWAKFREIADKVGAYLFVDMAHYAGLVAGGEYPNPVP
                     FCDFVTTTTHKTLRGPRGGVILCRDNTHEKALNSSIFPSLQGGPLMHVIAAKAVAFKE
                     ALQPEFKQYAKQVKINAAAMAEELVKRGLRIVSGRTESHVFLVDLQPMKITGKAAEAA
                     LGKAHITVNKNAIPNDPEKPFVTSGIRIGSAAMTTRGFNEADARVLANLVADVLSNPE
                     DEANLAKVREQVTALCNKYPVYGA"
     gene            complement(1497..1760)
                     /locus_tag="ACFOAE_001885"
     CDS             complement(1497..1760)
                     /locus_tag="ACFOAE_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885303.1"
                     /translation="MSNQTKIQAIKQASEQIFAICETPNTALQAIHLILRHGGAGELS
                     WQVVYQRVMADKDVVGAGYLIDFAQTAENLPFDVLPLGSLVLT"
     gene            complement(1823..3598)
                     /gene="ggt"
                     /locus_tag="ACFOAE_001886"
     CDS             complement(1823..3598)
                     /gene="ggt"
                     /locus_tag="ACFOAE_001886"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HFC6885304.1"
                     /translation="MAKTYLLTALIMSMTISGCQVIHANQGKVNTHSAVITGADAHTP
                     EHATGLIEQKQVIASDFMVASANPLATQAGYDILKQGGSAADAMVAVQTTLSLVEPQS
                     SGLGGGAFVLYWDNTAKTLTTFDGRETAPMRATPELFLDKDGQPLKFMEAVVGGRSVG
                     TPAIPKLMETIHQRYGVLPWGKLFDTPIRLAKQGFEVSPRLAISVEQNQQHLARYPKT
                     AAYFLPNGVPLQAGSLLKNLEFADSVQALAAQGAKALHTGKYAQNIVSVVQNAKDNPG
                     QLSLQDLSDYQVVERPPVCVTYRIYEVCGMGAPSSGGIAVGQILGILNEFSPNQVGYD
                     AEGLRLLGDASRLAFADRDVYLGDPDFVPVPIRQLISKDYLKHRSQLLEQSDKALPSV
                     SAGDFIHEWVSSQAIELPSTSHISIVDKAGNVLSMTTSIENAFGSTLMANGYLLNNEL
                     TDFSFEPIKQGKQVANRVEPGKRPRSSMAPTIVFKAGKPYMAIGSPGGSRIIGYVAKT
                     IVAHSDWNMDIQDAISAPNLLNRFGSYELETGTTALQWQQALNDLGYKTDVRELNSGV
                     QAIIIEPSRLVGGADPRREGRVMGD"
     gene            complement(3766..4028)
                     /locus_tag="ACFOAE_001887"
                     /pseudo
     CDS             complement(3766..4028)
                     /locus_tag="ACFOAE_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007116440.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin family protein"
BASE COUNT         1006 a          955 c          953 g         1114 t
ORIGIN      
        1 gattttgggg gattttgcaa aggtttccgc ctgaaacatt atgagatttc aggcggcatt
       61 ggattgcttg gcggaatatt tttaaaaagg cttacgcgcc gtaaacgggg tatttattgc
      121 acaaagcagt tacttgttcg cggactttgg cgaggttggc ttcgtcttcg gggttagaca
      181 atacgtcggc aaccaagttc gccaatacgc gcgcgtcggc ttcgttaaaa ccgcgtgtgg
      241 tcatggcggc ggaaccgatg cggatgccgg aggtaacgaa gggtttttcc ggatcgttcg
      301 gaatggcgtt tttgttgacg gtgatgtgcg ctttgcccaa agcggcttcg gcggctttgc
      361 cggtgatttt catcggttgc aggtcgacga ggaaaacgtg gctttcggtg cggccggaaa
      421 cgatgcgcaa accgcgtttg accagttctt ccgccatggc ggcagcattg attttcactt
      481 gttttgcgta ttgtttgaac tcgggttgca acgcttcttt aaacgctacg gctttggcgg
      541 cgatgacgtg catcagcgga ccgccttgca ggcttgggaa gatggaagag ttcaacgctt
      601 tttcgtgggt attgtcgcgg cacaaaatta cgccgccgcg aggaccgcgc agggttttgt
      661 gggtggtggt ggtaacgaag tcgcagaacg gcacgggatt gggatattcg ccgccggcaa
      721 ccagaccggc atagtgcgcc atatcgacaa agaggtatgc gccgacttta tcggcgattt
      781 cgcggaattt tgcccagtcg atttgcaacg cgtaggcaga cgcaccggcc acaatcattt
      841 taggtttgtg ttcgagagcc aagcgttcca cttcggcata atcgagcact tcgttttcat
      901 ccaagccata agtaacggcg ttgtagagtt tgccggaaat attaacgctc gcgccgtggg
      961 tcaggtggcc gccgtgcgct agagacatac ccaaaatggt gtcgcctggt tttaaaacgg
     1021 aagcgtacac ggcttggttg gcttgcgagc cggagtgcgg ttggacgttg gcgtattgcg
     1081 cgccgaacag ttttttgacg cggtcaatcg ccaattgttc gacaatatcg acgtattcgc
     1141 agccgccgta gtagcgtttg ccggggtagc cttcggcgta tttgttggtc agctgggaac
     1201 cttgcgcttc cattacggcg cagctgacgt agttttcaga ggcaatcagc tcgacgtggt
     1261 cttgctggcg ttggtcttct tgggcaatgg ctgctgccaa atcggggtca tattgtgcga
     1321 gggtaacgct ttttgaaaac atgttctcgg ctcctttgtg taatcagggt atcatgagtg
     1381 ttttttgtat aaaaaaatac ttcaaaacct aaggcagata gtccataatg cgtaaatttt
     1441 ctttggcatt atcaggtaat ttatttaaca tgctggtttt tagcgtctca ttacctttat
     1501 gttagtacaa ggctacccaa aggcaataca tcaaatggta aattttcggc agtttgtgca
     1561 aaatcaatca aataaccagc accaaccaca tctttatcag ccataacccg ctgatacacc
     1621 acttgccaag acaactctcc tgccccacca tgtcttaaaa tcagatgaat ggcttgtaat
     1681 gctgtgtttg gcgtctcaca aattgcgaag atctgctcag aagcttgctt gatggcttgt
     1741 atttttgttt gattactcac aatttccccc tattttaata ttaacttaat gcggtcaaat
     1801 tcacaaaata caagcttcac ctctaatcac ccatcactcg accttctcgg cgtggatcgg
     1861 caccaccaac cagcctgctt ggctcgataa taatggcttg aacacctgaa tttagctcac
     1921 gcacgtcagt cttatagccc aaatcattta atgcttgttg ccactggagg gcggttgtac
     1981 ccgtttctag ttcatagcta ccaaagcgat ttaataaatt gggtgcactg atggcatctt
     2041 ggatatccat attccagtca ctatgtgcca caatcgtctt agcgacatag ccaatgatac
     2101 ggctaccacc tggggagccg attgccatat aaggcttgcc tgctttaaat acgatggttg
     2161 gtgccattga ggagcgtggt ctcttgccgg gctcgacacg attggcgacc tgtttgccct
     2221 gctttattgg ctcaaaacta aagtctgtca gctcattatt cagcaggtag ccatttgcca
     2281 tcaaagttga gccaaacgca ttttcaatgg aagtcgtcat tgatagcaca ttgcccgcct
     2341 tatccacaat tgatatatga ctggtagaag gtaactcaat cgcttgtgag gacacccact
     2401 catgaataaa atcgcctgca gatacgctag gcaatgcctt atccgactgc tcaagcagct
     2461 ggctgcgatg ttttaggtag tctttagaaa tcaactggcg aatgggtact ggtacaaaat
     2521 cagggtcgcc caaatataca tcacgatccg caaacgcaag cctagaagcg tcgcccaaga
     2581 gacgtaaacc ttcagcatca taccccacct gattgggtga aaattcattt aaaatcccca
     2641 aaatttgacc cacagcaatc ccacctgagc ttggtgcacc cataccgcat acttcataaa
     2701 tacgataagt cacacaaaca ggcgggcgtt ccaccacttg ataatcagat aaatcttgta
     2761 aggataattg accggggtta tccttagcat tttggacaac tgaaacgata ttttgggcat
     2821 atttaccagt atgcagagct tttgcacctt gagctgctaa cgcctgaaca ctgtcagcaa
     2881 attctaaatt tttcagcaag ctgcctgctt gtagcggcac accattcggc aaaaaataag
     2941 cggctgtttt tggatagcgt gccaaatgct gctgattttg ctcaaccgag atggcaagcc
     3001 ttggcgacac ctcaaagcct tgttttgcca agcggatcgg tgtatcaaat aattttcccc
     3061 aaggcaatac accgtatcgc tgatgtattg tctccatcag tttagggata gcaggcgtac
     3121 ccaccgagcg accaccgacc accgcttcca taaatttcaa tggttgacca tctttatcca
     3181 aaaataattc cggcgtcgca cgcatcggtg ccgtctcacg cccatcaaat gtggtcaatg
     3241 ttttggcggt attatcccaa tacaacacaa atgcaccacc gcccaagcct gacgactgtg
     3301 gctctaccaa gcttagtgtc gtctgcaccg ccaccatcgc atctgcagcg ctaccgcctt
     3361 gctttaagat atcatagcca gcttgtgttg ctaatggatt ggctgacgct accataaaat
     3421 cacttgcaat cacctgcttt tgttcgatca gtcccgttgc atgttcaggc gtgtgagcgt
     3481 ctgcacctgt gatgacagca gaatgagtat taaccttacc ttgattggca tggatgactt
     3541 gacatccaga gattgtcata gacattatca atgcagtcaa taaatatgtt ttagccacaa
     3601 gcactccttc gcctgagttt gattgatgat tcatacaagg catgctgatt attgtattta
     3661 atatggctaa ataattcaat ccaaactatc aatcttgacc atcaaaaaaa gaccgctaat
     3721 gtcatcagca gtcttttttg atatttattt taagatatta agtaatcaga cctttgggct
     3781 atgctcttca atgagtggtt ttagctcacc tgattggtac atttgtagga taatatcact
     3841 accaccgatt aactcaccat taacccaaag ctgtggaaag gttggccgat tggcgatgag
     3901 tggtagagta ctgcgaattt ctgggttttc taggatatta acaaaagcaa agggtctgcc
     3961 aattgggtca gcacctctac tgcacgcgct gaaaatccac attggggaaa ctggggcgtg
     4021 cctttcat
//
LOCUS       DAXIDM010000137         3944 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000137 DAXIDM010000000
VERSION     DAXIDM010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.137"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            270..1391
                     /gene="dnaJ"
                     /locus_tag="ACFOAE_001888"
     CDS             270..1391
                     /gene="dnaJ"
                     /locus_tag="ACFOAE_001888"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFC6885305.1"
                     /translation="MSNQDFYATLGVARTATDDEIKKAYRKLAMKYHPDRNPDNKEAE
                     EKFKEVQKAYETLSDKEKRAMYDQYGHAAFEGGGQGGFGGFGGFGGAQGFDFGDIFSQ
                     MFGGGSGRAQPDYQGEDVQVGIEITLEEAAKGVKKRINIPTYEACDVCNGSGAKPGTS
                     PETCPTCKGSGTVHIQQAIFRMQQTCPTCHGAGKHIKEPCVKCRGAGRNKAVKTVEVN
                     IPAGIDDGQRIRLSGEGGPGMHGAPAGDLYVTVRIRAHKIFQRDGLDLHCELPISFAT
                     AALGGELEVPTLDGKVKLTVPKETQTGRRMRVKGKGVKSLRSSATGDLYCHIVVETPV
                     NLTDRQKELLEEFERISTGLENQTPRKKSFLDKLRDLFD"
     gene            1586..3604
                     /locus_tag="ACFOAE_001889"
     CDS             1586..3604
                     /locus_tag="ACFOAE_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006857 - oligopeptide transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OPT family oligopeptide transporter"
                     /protein_id="HFC6885306.1"
                     /translation="MNKSLSSSVEEYCELTLRGMILGALITVIFTASNVYLGLKVGLT
                     FASSIPAAVISMAVLKFFKGSNILENNMVQTQASAAGTLSTIIFVLPGLLMAGYWSGF
                     PFWQTTLLCIAGGILGVIFTIPLRYAMVVKSDLPYPEGVAAAEILKVGGHEEGDNRQG
                     GSGIKELAAGGALAGLMSFCAGGLRVIADSASYWFKSGTAIFQLPMGFSLALLGAGYL
                     VGLTGGIAILLGISIAWGIAVPYFSSHIPQPSDIEMAAFAMKLWKEKVRFIGAGTIGI
                     AAVWTLLMLLKPMVEGMKMSFKSFGGGAPATERAEQDLSPKAMIFWVLSMMFILGVSF
                     YHFIGDSHITGGMAWLLVVVCTLLASVIGFLVAAACGYMAGLVGSSSSPISGVGIVSV
                     VVISLVLLLVGESGGLLADEANRKFLLALTLFCGSAVICVASISNDNLQDLKTGYLLK
                     ATPWRQQVALIIGCIVGALVISPVLELLYEAYGFTGAMPREGMDAAQALAAPQATLMT
                     TIASGIFAHNLEWVYIFTGIAIGAVLIVVDLVLKKSSGGKLALPVLAVGMGIYLPPSV
                     NMPIVAGAVLAAVLKHIIGKKAENREGRLKNAERIGTLFSAGLIVGESLIGVIMAFII
                     AFSVTNGGSDAPLALNLQNWDAAASWLGLAFFVTGMFFFAQRVLKAGR"
     gene            complement(3648..>3944)
                     /locus_tag="ACFOAE_001890"
     CDS             complement(3648..>3944)
                     /locus_tag="ACFOAE_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFC6885307.1"
                     /translation="EGSPTFGKWVGEILSAQNQCQLWIPEGFAHGFCVLSDTTELTYK
                     CTDYYKPEAEQVLIWNDPAIGIGWPLQTAPLLSPKDLAGKAWAQAEKLRLTLSR"
BASE COUNT          844 a          893 c         1163 g         1044 t
ORIGIN      
        1 aataagggga agtctgcagc cgcatcaaat gccgtctgaa catgcgttcg ggcggcgttt
       61 ttataacaaa aacacttcat ggcgggttgg ttttatgcct gtctaagttt ttgtgtcgtg
      121 catacctgaa aatttcagac ggcatcggtt tatgctgtct gaaaagtgta ttccgtttca
      181 gtttgtaagc tatggcagtc tgtttgtctt gtgttttgcg caattgccct tattttgagc
      241 cgtgatttta ttttgaatta gatgaaaaaa tgagtaatca agatttttat gcgacgctgg
      301 gtgtggcaag aacagctacc gatgatgaga ttaaaaaagc ctaccggaaa ttggcgatga
      361 aatatcatcc cgaccgcaat cctgacaata aagaggcgga agagaagttt aaagaagtac
      421 aaaaggcgta tgaaactttg tccgacaagg aaaagcgcgc tatgtacgac cagtatggtc
      481 atgcggcgtt tgaaggcggc ggacaggggg gcttcggagg gtttggcgga tttggcggtg
      541 cgcagggttt tgactttggg gatattttca gccaaatgtt tggaggcggt tcggggcgcg
      601 cccagcctga ttatcagggt gaggacgttc aagtcggtat cgaaatcacg cttgaagaag
      661 ccgcaaaagg tgtgaagaaa cgcatcaata ttccgactta tgaagcgtgt gatgtctgta
      721 acggcagtgg cgcgaaaccg gggacatccc cggaaacctg cccgacttgc aaaggttcgg
      781 gtacggtgca catccagcag gcgattttcc gtatgcagca gacttgtccg acctgccacg
      841 gtgcgggcaa acacattaaa gaaccttgcg tcaaatgccg tggcgcgggg cggaataagg
      901 cggtcaagac ggtggaagtc aatattcccg ccggtatcga tgacgggcag cgtatccgtt
      961 tgagcggcga aggcggaccg ggtatgcacg gtgcgcctgc tggcgacctg tatgtaaccg
     1021 tccgcattcg ggcgcataag attttccaac gcgacggtct ggacttgcat tgcgaactgc
     1081 cgatcagttt tgccacggct gctttgggcg gggagttgga agtgccgacc ttggacggaa
     1141 aggtcaagct caccgtcccc aaagaaaccc aaaccggcag gaggatgcgc gtgaagggta
     1201 agggtgtcaa atctttacgc agcagcgcga ccggcgattt gtactgccat attgttgtcg
     1261 aaacgcctgt caatttgacc gaccgtcaaa aagagctttt ggaagaattt gagcggattt
     1321 ctaccggctt ggaaaaccaa acaccgcgca agaaatcgtt tttagacaag ctgcgcgatt
     1381 tgtttgattg attttaaggt tcggaaacaa gcagccgtat cggggaatct ccctgatacg
     1441 gctgttttgt ttgtttaaaa atagttttta ttttcaatgg ggtatggggc agggtgggat
     1501 aactgttttt aactgttctt tttaaaactt gacatcatgg cgcgatgcca acaatatgtg
     1561 aacgtctgtt gtcaaaggaa gaataatgaa taaatcttta tccagttcgg tagaagaata
     1621 ctgcgagctg acgctccgag gcatgatact cggtgcattg atcactgtaa tttttactgc
     1681 gtccaatgtt tacctcggtt tgaaagtcgg gctgaccttt gcctcgtcga ttccggcggc
     1741 ggtgatttcg atggcggttt taaagttttt caaaggcagc aatattttgg aaaacaacat
     1801 ggtgcagacc caagcctcgg ctgcgggtac gctttcaacc atcatcttcg tcctgcccgg
     1861 tttgctgatg gcgggctact ggagcggttt cccgttctgg cagacgacgc ttttatgtat
     1921 tgccggcggg attttggggg tgattttcac cattccgctg cgttacgcga tggtggtgaa
     1981 aagcgatttg ccttatccgg aaggtgtggc ggctgctgaa attttgaaag tgggcggtca
     2041 tgaagaaggg gataaccgtc agggcggcag cggcatcaaa gagctggcgg ccggcggtgc
     2101 gttggcggga ttgatgagct tttgcgccgg aggtctgcgt gtgattgccg atagcgcgag
     2161 ttattggttt aaaagcggta cggcaatttt ccaactgccg atgggctttt cactggcatt
     2221 gttgggcgcg ggctatttgg tcggactgac gggcggtatc gccattctgt tgggcatttc
     2281 gattgcttgg ggcattgccg tgccgtattt ttcatcgcac atcccgcagc cttccgatat
     2341 agaaatggcg gcgtttgcga tgaagctgtg gaaggaaaaa gtacgcttca tcggcgcggg
     2401 aaccataggt atcgcggcgg tttggacgct tttgatgctg ctcaagccaa tggtggaagg
     2461 catgaagatg tcgttcaaga gttttggcgg cggtgcgccc gcaacagaac gcgccgaaca
     2521 ggatttgtcg cctaaagcca tgattttctg ggtattgtct atgatgttta ttctaggcgt
     2581 gtcgttttac cactttatcg gcgattcgca cattacgggc ggcatggctt ggcttttggt
     2641 ggtcgtttgc acgcttttgg cttccgtcat cggctttttg gtcgccgccg cctgcggtta
     2701 tatggcaggt ttggtcggct cgtcttccag cccgatttcc ggcgtgggca tcgtgtccgt
     2761 cgtcgttatt tcactggttt tgctgctggt aggcgaatcc ggaggtttgt tggcggatga
     2821 ggctaaccgc aaatttttgc tggcactgac tttgttttgc ggctcggcag taatctgcgt
     2881 ggcttcgatt tccaatgaca acctgcaaga cttgaaaacc ggctacctgc tcaaagccac
     2941 gccttggcgg cagcaagtcg ccctgattat cggctgtatc gttggtgcgc tggttatttc
     3001 gcccgtgttg gaactgcttt acgaagccta cggctttacc ggcgcaatgc cgcgcgaagg
     3061 catggatgcg gcgcaggctt tggcagcacc tcaagcgact ttgatgacga ccatcgcgtc
     3121 gggcattttc gcccacaacc tcgaatgggt ctacatcttt accggcatcg cgattggagc
     3181 ggtattaatc gtcgtcgatt tggtgttgaa aaaatcatca ggcggtaaac ttgccctgcc
     3241 cgtccttgcg gtcggtatgg gtatttatct gccgccgtcc gtcaatatgc ccatcgtggc
     3301 aggcgcggtg ttggcggcag tgttgaaaca catcatcggt aaaaaagcgg aaaaccgtga
     3361 aggccgtctg aaaaacgccg agcgcatcgg aaccttgttc tccgccggcc tgattgtcgg
     3421 tgaaagcctg atcggtgtga ttatggcgtt tattattgcc ttctccgtga ccaacggcgg
     3481 ctcggatgcg ccgcttgcgt tgaatctgca aaactgggat gccgccgcct catggttggg
     3541 cttggcgttc ttcgttaccg ggatgttttt ctttgcacag cgcgtactga aggcgggtag
     3601 gtagcctgtc ggaaaaaatg ccgtctgaaa cgttcagacg gcatttttta tcgggaaagc
     3661 gtaaggcgga gcttttcggc ttgcgcccac gctttaccgg caagatcttt gggcgacagc
     3721 agcggcgcgg tttgaagcgg ccagcctatg ccgattgccg ggtcgttcca tattaaaacc
     3781 tgttcggctt caggcttgta atagtccgtg catttgtagg taagttcggt cgtgtcgctc
     3841 aaaacgcaaa acccgtgcgc gaagccttcg ggtatccaaa gctggcattg gttttgcgcg
     3901 gacagaatct cgcctaccca tttgccgaaa gtcggcgaac cttc
//
LOCUS       DAXIDM010000138         3868 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000138 DAXIDM010000000
VERSION     DAXIDM010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3868
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.138"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(88..906)
                     /locus_tag="ACFOAE_001891"
     CDS             complement(88..906)
                     /locus_tag="ACFOAE_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002259846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFC6885308.1"
                     /translation="MKGMDKLRYQQDFLNIRPIFTAGEQEYLTGLSDRLPLSVLTGSV
                     RNIEEIGIDFVYSSAKLEGNTYNQYDTQALLKLGQTAGGKLYSDAVMLINLRESYRHL
                     LSGLDRPDPFDWLDFLKTTHSLISENLLEKGSGGVVRRDSVTISGTDYTPLSNPQSLD
                     TELKWLLQEAPKIGNPFDRSVYLHNNLAYLQYFKDCNKRTARNCMTLSLMRSGFFPCV
                     FAPDSYPAYAEAVVAYYETGDYGLFKKYFISAYENTVNKYGPQPDMDIFRNFSL"
     gene            complement(973..2223)
                     /locus_tag="ACFOAE_001892"
     CDS             complement(973..2223)
                     /locus_tag="ACFOAE_001892"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA];
                     GO_process: GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFC6885309.1"
                     /translation="MTKLTRRQIIRRTAGTLFALSPIASAVAKTVRAPQFTAVRIWPS
                     HTYTRLTLESTTALKYQHFTLDNPGRLVVDIQNANINTVLHGLSQKVMADDPFIRNIR
                     AGQNTPDTVRLVIDLKQPSYAQVFSLPPVGGFKNRLVVDLYPQGMDPDDPMMALLNGS
                     LNKTRRGSPEADLAQNTPAQTERGKNGRRPVIMIDPGHGGEDPGAVSPGGLQEKHVVL
                     SIARETKKQLEALGYNVFMTRNEDVFIPLGVRVAKGRARRADVFVSIHADAFTSPSAR
                     GTGVYMLNTKGATSSAAKFLEQTQNNADAVGGVPTSGNRNVDTALLDMTQTATLRDSR
                     KLGKLVLEELGRLNHLHKGRVDEANFAVLRAPDMPSILVETAFLSNPAEEKLLGSESF
                     RRQCAQSIASGVQRYINTSVLKRG"
     gene            complement(2220..2681)
                     /gene="tsaE"
                     /locus_tag="ACFOAE_001893"
     CDS             complement(2220..2681)
                     /gene="tsaE"
                     /locus_tag="ACFOAE_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFC6885310.1"
                     /translation="MSDLPSISRFLADEAATLDLGAAWSSRLNAPLVIYLEGDLGAGK
                     TTLTRGILRGLGHLGAVKSPTYAIVESYPLERFTLHHFDLYRFSFPEEWEDAGLDELF
                     AANSVCLIEWPQQGGEFTPPADITATLTHDGGGRKCLLTAHTERGRESLPL"
     gene            2883..3695
                     /gene="murI"
                     /locus_tag="ACFOAE_001894"
     CDS             2883..3695
                     /gene="murI"
                     /locus_tag="ACFOAE_001894"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFC6885311.1"
                     /translation="MENIGRQRPIGVFDSGIGGLTNVRALMERLPMENIIYFGDTARV
                     PYGTKSKATIENFSMQIVDFLLEHDVKAMVIACNTIAAVAGQKIRQKTGNMPVLDVIS
                     AGAKAALATTRNNKIGIIATNTTVNSNAYARAIHRNNPDTLVRTQAAPLLVPLVEEGW
                     LEHEVTRLTVCEYLKPLLADGIDTLVLGCTHFPLLKPLIGREAHNVALVDSAITTAEE
                     TARVLAQEGLLNTDNNNPDYRFYVSDIPLKFRTIGERFLGRTMEQIEMVSLG"
BASE COUNT          849 a          959 c         1140 g          920 t
ORIGIN      
        1 cactataacc gaaggtaagg gaggggcgtg tccattttgc cgccgcattt gccgcgtgcg
       61 gaagatacgg ataacaaccc cttggaatta aagggagaag ttgcggaaaa tatccatatc
      121 aggctgtggg ccgtacttat ttacggtatt ttcgtatgcc gaaataaaat atttcttgaa
      181 taaaccgtaa tcgccggttt cgtaataggc tacgacagcc tcggcatagg cgggataact
      241 gtcgggggcg aatacgcaag gaaaaaaacc ggagcgcatc agcgataggg tcatgcagtt
      301 tctggcagta cgtttattgc aatctttaaa atattgaaga tacgccaaat tattatggag
      361 ataaacggag cggtcgaagg gatttcctat ttttggggct tcttgaagca accattttaa
      421 ttccgtatcc aaactttgcg ggttagataa aggggtgtag tctgtcccgc ttatggtaac
      481 gctgtcgcgg cggactacgc cgccggagcc tttttccagt aagttttccg aaatcaggct
      541 gtgggtggtt tttaagaaat ccaaccagtc aaacggatcg gggcggtcca aaccggacag
      601 caggtgccgg taactttccc tcaggttgat taacattacg gcatccgaat ataacttccc
      661 gcctgcggtt tgcccgagtt taagcaatgc ctgcgtatcg tattgattat aagtgtttcc
      721 ttccaatttg gcagaactat atacaaaatc gataccgatt tcttcaatat tacgcacgga
      781 gcccgttaaa acagataaag gaagccgatc ggacaatccg gtcaggtatt cttgttcgcc
      841 ggctgtaaaa atggggcgga tatttaaaaa atcctgttgg tatctcaatt tatccatacc
      901 tttcatcata aaaacgcggt ttggggcgga agtaggttta tgcctgcctt catccgacta
      961 ccgccttttc aatcaacccc gcttcaatac ggatgtattg atgtagcgtt ggacacccga
     1021 ggcaatggat tgggcgcact gccggcggaa ggattcgctg cccagcaact tctcttcagc
     1081 agggttggac aggaaggcgg tttcgaccag gatagacggc atatcgggtg cgcgcaaaac
     1141 ggcgaaattg gcttcgtcca ccctgccttt gtgcaagtgg ttgagcctgc ccaattcttc
     1201 aagcaccagt ttgccgagtt tgcggctgtc gcgcagcgtg gcggtttggg tcatatcgag
     1261 cagggcggta tcgacgttgc ggttgccgct ggtcggtacg ccgccgaccg cgtcggcatt
     1321 gttttgcgtc tgttccaaga atttggcggc ggagctggtc gcgcctttgg tgttcagcat
     1381 ataaaccccc gttccgcgcg cggaggggct ggtgaaagcg tcggcgtgga tggagacgaa
     1441 tacgtccgcc cgccgtgctc gccctttggc gacacgcacg cccaatggga tgaacacgtc
     1501 ttcgttgcgc gtcataaaga cgttgtaacc caaggcttcc aattgttttt tggtttcgcg
     1561 ggcgatggag aggacgacgt gtttttcctg caaaccgccc gggctgacgg cgccggggtc
     1621 ttcgccgccg tgtccggggt cgatcataat gacgggtctg cgcccgtttt tgccgcgttc
     1681 ggtttgtgcg ggagtgtttt gagcgaggtc ggcttcaggg gagccgcgac gggttttgtt
     1741 caggctgccg ttaagcagcg ccatcatcgg atcgtcggga tccatccctt gcggatagag
     1801 atcgacgacg aggcggtttt taaagccgcc gacggggggg agggaaaaaa cttgcgcgta
     1861 ggaaggctgt ttcaaatcga tgacgaggcg gacggtgtcg ggcgtgttct gaccggcgcg
     1921 tatattgcgg ataaaggggt cgtccgccat aaccttctga gacagtccgt gcaatacggt
     1981 attgatgttc gcgttttgta tgtcgacgac caacctgccc gggttgtcga gcgtgaagtg
     2041 ttggtatttg agcgcggttg tgctttccag cgtcaggcgg gtgtaggtgt gcgacggcca
     2101 tatccgtacg gcggtaaact gcggggcgcg taccgttttg gcaacggcgg atgcgatggg
     2161 gcttagggcg aacagtgtgc cggcggtgcg gcggatgatt tgtcttcgtg tcagtttggt
     2221 catagcggca ggctttcgcg tcctcgttcg gtatgggcgg tcagcaggca ttttctgccg
     2281 ccgccgtcgt gtgtcaatgt tgcggtgatg tcggcgggcg gggtaaattc gcctccctgt
     2341 tgcggccatt cgatcaggca gacgctgttt gcggcaaaca gttcgtcaag ccccgcgtct
     2401 tcccattctt cggggaacga gaagcggtag aggtcgaaat ggtgcagggt gaagcgttcc
     2461 agcggataag attcgacgat ggcgtaagtc gggcttttga ctgcgcccag atgacctaat
     2521 ccgcgcagga tgccgcgtgt cagcgtggtt ttgcccgcac ccaaatcccc ttcgagataa
     2581 atgaccagcg gtgcgtttaa acgggaagac cacgccgcgc ccaaatcgag tgtggcggct
     2641 tcatcggcaa ggaatcggga gatagagggt aaatcagaca tggaaacggt ttgttgtaag
     2701 gtctagggta ttatgggcag ttttgcaggt tttgcaaact ttgcacccga ggggcggatg
     2761 cttcttgtcc gagcattata acagccaaat ccgcgttctg ctttcagacg gcaacggctg
     2821 tcaagaaaaa gcggcgcgtg tacaatacgc ggattgtatg tttaggacag attggaaaaa
     2881 ggatggaaaa tatcggcagg cagcgaccca tcggcgtttt tgactcggga atcggcggtt
     2941 tgaccaatgt gcgcgcgctg atggagcggc tgccgatgga gaacatcatt tatttcggcg
     3001 atacggcgcg cgtgccttac gggacgaaat ctaaggcgac catcgaaaat ttctcgatgc
     3061 agattgttga ttttttattg gaacacgatg tcaaggcgat ggttatcgcg tgcaacacga
     3121 ttgcggcggt ggcggggcag aaaatccgtc aaaagacggg taatatgcct gtgttggacg
     3181 tgatttccgc cggcgcgaaa gccgcgctgg caacgacgcg caacaataaa atcggcatca
     3241 tcgccaccaa tacgacagtc aacagcaacg cctatgcgcg cgccatccac aggaacaacc
     3301 ccgacacgct cgtccgcacg caggccgcgc cgctgctcgt ccctttggtg gaagagggct
     3361 ggttggaaca cgaagttacc cgcctgaccg tatgcgaata cctcaaacca ttgcttgcgg
     3421 acggcatcga tacgctggtg ttgggctgca cgcactttcc cttgctcaaa cccttaatcg
     3481 gcagggaggc gcacaatgtc gcactggtcg attccgcgat tacgactgcc gaagaaaccg
     3541 cacgcgtcct tgcgcaggag ggattactca ataccgacaa caacaatccc gactaccgtt
     3601 tttatgtcag cgatattcct ttgaaattca gaaccatcgg cgagcgtttt ctgggcagga
     3661 cgatggagca gattgaaatg gtgtctttgg gttagcggca ggtacggacg gaaaccgtcc
     3721 ccgtccgcgc catccgcata cgcacccgca acgccctgcc gtattaaacg ccccgtcgcc
     3781 gcaaatgccg tctgaaaggc ttcagacggc attttttaca caattcccac cgtttcccat
     3841 ccttctcgat acactgtaat ctcgaaat
//
LOCUS       DAXIDM010000139         3862 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000139 DAXIDM010000000
VERSION     DAXIDM010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3862
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.139"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            500..3701
                     /gene="nalP"
                     /locus_tag="ACFOAE_001895"
                     /pseudo
     CDS             500..3701
                     /gene="nalP"
                     /locus_tag="ACFOAE_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248900.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine endopeptidase autotransporter NalP"
BASE COUNT         1056 a         1044 c         1025 g          737 t
ORIGIN      
        1 aaagcaacag gcatttatcg gaaataactg aaaccgaaca gacctagatt cccgcctgcg
       61 cgggaatgac ggctgcagat gcccgacggt ctttatagcg gattaacaaa aatcaggaca
      121 aggcgacgaa gccgcagaca gtacagatag tacggaaccg attcacttgt taaagaatcg
      181 ttctctttga gctaaggcga ggcaacgccg tactggtttt tgttcatcca ctataactag
      241 ggaaattcaa attaagttag aattatccct atgagaaaaa gccgtctaag ccggtataaa
      301 caaaataaac tcattgagct atttgtcgaa agttcaaatt tccattttaa aacaattagt
      361 aaaatcgagt ttatcctagt tgtccaagac aacccctata ataatataat tcaaaatata
      421 aaaatgggtt acatctaaac attacggaat ttttattccc tcgcctgaat tctattgtca
      481 gattcaagga gacctcatca tgcgaacgac cccaaccttc cctacaaaaa ctttcaaacc
      541 ggctgccatg gcgttagctg ttgcaacaac actttctgcc tgcttaggcg gcggcggcgg
      601 cacttctgcg cccgacttca atgcaggcgg caccggtatc ggcagcaaca gcagagcaac
      661 aacagcgaaa tcagcagcag tatcttacgc cggtatcaag aacgaaatgt gcaaagacag
      721 aagcatgctc tgtgccggtc gggatgacgt tgcggttaca gacagggatg ccaaaatcaa
      781 tgcccccccc gaatctgcat accggagact ttacaaaccc aaatgacgca tacaagaatt
      841 tgatcaacct caaacctgca attgaagcag gctatacagg acgcggggta gaggtaggta
      901 tcgtcgatac aggcgaatcc gtcggcagca tatcctttcc cgaactgtat ggcagaaaag
      961 aacacggcta taacgaaaat tacaaaaact atacggcgta tatgcggaag gaagcgcctg
     1021 aagacggagg cggtaaagac attaaagctt ctttcgacga tgaggccgtt atagagactg
     1081 aagcaaagcc gacggatatc cgccacgtaa aagaaatcgg acacatcgat gtggtctccc
     1141 atattattgg cgggcgttcc gtggacggca gacctgcagg cggtattgcg cccgatgcga
     1201 cgctacacat aatgaatacg catgatggaa ccaagaacga aataatgtct gcagccatcc
     1261 gcaatgcatg ggtcaagctg ggcgaacgtg gcgtgcgcat cgtcaataac agttttggaa
     1321 caacatcgag ggcaggcact gccgaccatt tccaaatagc caattcggag gagcagtacc
     1381 gccaagcgtt gctcgcctat tccggcggtg ataaaacaga cgagggtatc cgcctgatgc
     1441 aacagagcga ttacggcaac ttgtcctacc acatccgtaa taaaaacatg cttttcattt
     1501 tttcggcaag caatgacgca caagctcagc ccaacacact gaccctattg ccattttatg
     1561 aaaaagatgc tcaaaaaggc attatcacag tcgcaggcgt agaccgcagt ggagaaaagt
     1621 tcaatggctc caaccattgc ggaattactg ccatgtggtg cctatcggca ccctatgaag
     1681 caagcgtccg tttcacccgt acaaacccga ttcaaattgc cggaacatcc ttttccgcac
     1741 ccatcgtaac cggcacggcg gctctgctgc tgcagaaata cccgtggatg agcaacgaca
     1801 acctgcgtac cacgctgctg acaacggctc aggacatcgg tgcagtcggc gtggacagca
     1861 agttcggctg gggactgctg gatgcgggta aggccatgaa cggacccgcg tcctttccgt
     1921 tcggcgactt taccgccgat acgaaaggta catccgatat tgcctactcc ttccgtaacg
     1981 acatttcagg cacgggcggc ctgatcaaaa aaggcggcag ccaactgcaa ctgcacggca
     2041 acaacaccta tacgggcaaa accattatcg aaggcggttc gctggtgttg tacggcaaca
     2101 acaaatcgga tatgcgcgtc gaaaccaaag gtgcgctgat ttataacggg gcggcatccg
     2161 gcggtagcct gaacagcgac ggcattgtct atctggcaga taccgaccga tccggcgcaa
     2221 acgaaaccgt gcacatcaaa ggcgatctgc agctgggcgg cgaaggtacg ctgtacacac
     2281 gtttgggcaa actgctgaaa gtggacggta cggcgatgac cggcggcaag ctgtacatgt
     2341 cggcacgcgg caaaggggca ggctatctca accgtaccgg acaacgtgtt cccttcctga
     2401 gtgccgccaa aatcgggcgg gattattctt tcttcacaaa catcgaaacc gacggtggtc
     2461 tgctggcttc cctcgacagc gtcgaaaaaa cagcgggcag tgaaggcgac acgctgtcct
     2521 attatgtccg tcgcggcaat gcggcacgga ctgcttcggc agcggcacat tccgcgcccg
     2581 ccggtctgaa acacgccgta gaacagggcg gcagcaatct ggaaaacctg atggtcgaac
     2641 tggatgcctc cgaatcatcc gcaacacccg agacggttga aactgcggcc gccgaccgca
     2701 cagatatgcc gggcatccgc ccctacggcg caactttccg cgcagcggca gccgtacagc
     2761 atgcgaatgc cgccgacggt gtacgcatct tcaacagtct cgccgctacc gtctatgccg
     2821 acagtaccgc cgcccatgcc gatatgcagg gacgccggct gaaagccgta tcggacgggt
     2881 tggaccacaa cgctacgggt ctgcgcgtca tcgcgcaaac ccaacaggac ggtggaacgt
     2941 gggaacaggg cggtgttgaa ggcaaaatgc gcggcagtac ccaaaccgtc ggcattgccg
     3001 cgaaaaccgg cgaaaatacg acagcagccg ccacactggg catgggacac agcacatgga
     3061 gcgaaaacag tgcaaatgca aaaaccgaca gcattagtct gtttgcaggc atacggcacg
     3121 atgcgggcga tatcggctat ctcaaaggcc tgttctccta cggacgctac aaaaacagca
     3181 tcagccgcag caccggtgcg gacgaacatg cggaaggcag cgtcaacggc acgctgatgc
     3241 agctgggcgc actgggcggt gtcaacgttc cgtttgccgc aacgggagat ttgacggtcg
     3301 aaggcggtct gcgctacgac ctgctcaaac aggatgcatt cgccgaaaaa ggcagtgctt
     3361 tgggctggag cggcaacagc ctcactgaag gcacactggt cggactcgcg ggtctgaagc
     3421 tgtcgcaacc cttgagcgat aaagccgtcc tgtttgcaac ggcgggcgtg gaacgcgacc
     3481 tgaacggacg cgactacacg gtaacgggcg gctttaccgg cgcgactgca gcaaccggca
     3541 agacgggggc acgcaatatg ccgcacaccc gcctggttgc cggtctgggc gcggatgtcg
     3601 aattcggcaa cggctggaac ggcttggcac gttacagcta cgccggttcc aaacagtacg
     3661 gcaaccacag cggacgagtc ggcgtaggct accggttctg acggacagga agcagacagc
     3721 cgcaaagatc acggtctttg cggctgtttc ttatgaaaag aaaaccctat tccaattgcc
     3781 tgcttctatt gtttcaagac ttcttccaaa gattcggcat taatcagatg tatagcggat
     3841 taacaaaaat caggacaagg cg
//
LOCUS       DAXIDM010000140         3859 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000140 DAXIDM010000000
VERSION     DAXIDM010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3859
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.140"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            490..1446
                     /gene="thiL"
                     /locus_tag="ACFOAE_001896"
     CDS             490..1446
                     /gene="thiL"
                     /locus_tag="ACFOAE_001896"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009030 - thiamine-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HFC6885312.1"
                     /translation="MKEFDFIKRYLQTGTDNDVVLGIGDDAAIVRPREGFDLCFSADM
                     LLKDRHFFADVKPEDLAWKVLAVNISDMAAMGAIPRWVLLSAALPELDEVWLKRFCGS
                     FFGLAKKFGVTLIGGDTTKGDMAFNVTIIGELPKGRALRRDAAVAGDDIWVSGRVGMA
                     AAALNCRLKRCVLPDDVFAECEQKLLRPEPRVGLGLALLPFARAAQDVSDGLAQDLGH
                     ILTASGVGAEIWADSLPSLSVLKDILPRAQWLSYTLAGGDDYELVFTAPESCRSRVLD
                     AAERCGVPVTRIGKINGGCRLKVLDADGRELELHSLGFDHFG"
     gene            1439..1924
                     /locus_tag="ACFOAE_001897"
     CDS             1439..1924
                     /locus_tag="ACFOAE_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFC6885313.1"
                     /translation="MADFKPDFAWLLKRPLCFLAFGFGSGLAPFAPGTFGTLAALPLA
                     FVLILLGIDGLLLAFLCIVLFMWGIRICAYAERETGVSDHGGIVWDEIVAMLFVLAFV
                     PFRWTWWLAAFVLFRLFDALKPSPVGWFDKNLHGGLGIMADDMAAAVMTLIVLRIAML
                     F"
     gene            complement(1984..3660)
                     /gene="ettA"
                     /locus_tag="ACFOAE_001898"
     CDS             complement(1984..3660)
                     /gene="ettA"
                     /locus_tag="ACFOAE_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0045900 - negative regulation of
                     translational elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HFC6885314.1"
                     /translation="MSQQYVYSMLRVSKVVPPQKTIIKDISLSFFPGAKIGLLGLNGA
                     GKSTVLRIMAGVDKEFEGEAVPMGGIKIGYLPQEPELDPEKTVREEVESGLGEVAAAQ
                     KRLEEVYAEYANPDADFDALAEEQGRLEAIIAAGSSTGGGAEHELEIAADALRLPEWD
                     AKIGNLSGGEKRRVALCKLLLSKPDMLLLDEPTNHLDAESVEWLEQFLVRFPGTVVAV
                     THDRYFLDNAAEWILELDRGHGIPWKGNYSSWLEQKEKRLENEAKSEAARVKAMKQEL
                     EWVRQNAKGRQAKSKARLARFEEMSNYEYQKRNETQEIFIPVAERLGNEVIEFVNVSK
                     SFGDKVLIDDLSFKVPAGAIVGIIGPNGAGKSTLFKMIAGKEQPDSGEVKIGQTVKMS
                     LIDQSREGLQNDKTVFDNIAEGRDILQVGQFEIPARQYLGRFNFKGSDQSKITGQLSG
                     GERGRLHLAKTLLGGGNVLLLDEPSNDLDVETLRALEDALLEFAGSVMVISHDRWFLD
                     RIATHILACEGDSKWVFFDGNYQEYEADKKRRLGEEGAKPKRIKYKPVTR"
BASE COUNT          778 a          949 c         1080 g         1052 t
ORIGIN      
        1 aaggcaacgc tgtactggtt taaatttaat ccactatatc ggttgaaact ctgattttaa
       61 ggcggtagga tgtgggtttg cccatagaaa gggaatcctt tctgtatcaa gccctgaaag
      121 ggataattca tacaaattca cgcctttccc cttcattggg aaatggatgg aatcgtgcca
      181 gatgtgtgcg gcactgtatg ccggatatgg ttttatcatc agcccttttc ggttgaaacc
      241 ccgtcagttg cagcgattga gcctaatcgg tggcggaagt tgccgctttg cattcggggc
      301 ggcgtgcagt gcggtgcttt gatatgccgt ttgtgtgttg aaacagggtg gtcggtgcat
      361 acgggtacgg tatggccaaa gctaaaagtg aaatacgctg aaacactgaa tgagccgctt
      421 tattgtttgt acggcctttg ctgccttgct atgatttaaa ttggattcgc ccgccggata
      481 ttttgggata tgaaagaatt tgacttcatc aaacggtatt tgcaaacagg cacggataat
      541 gatgtcgtat tgggcatagg cgacgatgcg gcgattgtcc gcccgcgtga aggcttcgat
      601 ttgtgtttca gtgcggatat gcttttgaag gacaggcatt tttttgcaga tgtcaaacct
      661 gaagacttgg cttggaaggt tttggccgtc aatatttcag atatggcggc gatgggtgcg
      721 ataccgcgtt gggtgttgct gagcgcggct ttgcccgaat tggatgaggt atggctgaaa
      781 cggttttgcg gcagcttttt cggtttggca aaaaagtttg gcgtaacgtt aatcggcggc
      841 gatacgacca agggcgatat ggcgttcaat gtaaccatta tcggcgaatt gccgaagggt
      901 agggcgttgc ggcgtgatgc ggcggttgcg ggcgacgata tttgggtgtc ggggcgtgtc
      961 ggtatggcgg cggcggcttt gaactgccgt ctgaaacggt gtgtgttgcc ggatgatgtg
     1021 tttgccgaat gcgaacaaaa gctgctccgc cccgagccaa gggttgggct ggggcttgcg
     1081 ctgttgccgt ttgcccgggc ggcgcaggat gtttcagacg gcctcgcgca agatttgggg
     1141 catatcctga ccgcttccgg cgtgggggcg gaaatttggg ccgattcgct gccgtcttta
     1201 tccgtattga aagatatttt gccccgagcg caatggctgt cttatacttt ggcgggcggc
     1261 gacgattacg agctggtgtt taccgcgccg gaaagttgcc gcagccgcgt gcttgatgcg
     1321 gcagaacggt gcggcgtgcc ggtaacgcgc atcggcaaaa tcaacggagg atgccgtctg
     1381 aaggttttag atgccgacgg cagggaattg gaactacatt ctttaggatt cgatcatttt
     1441 ggctgatttt aaacctgact ttgcgtggct gttgaaacga ccgttgtgtt ttttggcttt
     1501 tggtttcggc agcgggctgg ctccgttcgc gccgggtaca tttggcactt tggcggcact
     1561 gcctttggca tttgtgctga ttttgctcgg catagacggg ctgctgctgg cttttttgtg
     1621 tatcgtgctg tttatgtggg gcatacgcat ttgcgcttat gcggaacgtg aaacgggtgt
     1681 cagcgaccat ggtgggattg tttgggacga gattgtcgcc atgctgtttg tgctggcgtt
     1741 tgtgccgttc aggtggacgt ggtggctggc ggcatttgtc ctattccgtc tgtttgacgc
     1801 gctcaaaccg tctcccgtcg gttggtttga caagaatctg cacggcggtt tgggcattat
     1861 ggcggacgat atggcggctg cggtgatgac tttgattgtc ttgaggattg caatgctgtt
     1921 ttaaacggtg ctgccttgta aaaatgccgc ctgaaagcct ttcagacggc attgtttcgg
     1981 aggttaacgc gttaccggtt tgtatttgat gcgtttcggt ttcgcgcctt cttcgccgag
     2041 tcggcgtttc ttgtcggctt cgtattcctg atagttgccg tcgaagaaca cccatttgga
     2101 gtcgccttcg caagccaaga tatgcgtagc aatacggtcg aggaaccaac ggtcgtgcga
     2161 aatcaccatc acgctaccgg caaattccag caatgcgtct tccagcgcgc gcagggtttc
     2221 tacgtcaagg tcattggacg gttcgtccaa cagcaataca ttgccgccgc ccaacaaggt
     2281 ttttgccaag tgcaaacgtc cgcgttcgcc gccggaaagc tgccccgtga ttttgctttg
     2341 gtcgctgcct ttgaaattga agcgtcccaa atattggcgg gcgggaattt caaactgacc
     2401 aacctgcaaa atgtcgcggc cttcggcgat gttgtcgaac acggttttgt cgttttgcaa
     2461 accttcgcgg ctttggtcaa tcaggctcat tttcacggtt tgcccgattt tcacttcgcc
     2521 cgaatcgggc tgctctttgc ccgcaatcat tttaaacagc gtcgatttac ccgcgccatt
     2581 cgggccgatg atgccgacaa tcgcgcccgc aggcactttg aagctcaaat catcaatcag
     2641 cactttgtcg ccgaacgatt tggaaacatt cacaaattca atcacttcgt tacccaaacg
     2701 ctcggcaacg ggaatgaaaa tttcctgagt ttcgttgcgt ttttggtatt cgtagttgct
     2761 catttcctcg aaacgcgcca aacgcgcttt ggacttggct tgacggcctt tggcattttg
     2821 gcgcacccat tccaattcct gcttcatcgc cttcacacgc gcggcttcgg atttcgcctc
     2881 gttttccaag cgtttttctt tctgctccag ccaagacgag taattgcctt tccacggaat
     2941 accgtgtccg cggtcgagtt ccaaaatcca ttcggcggca ttgtcgagga agtagcggtc
     3001 gtgtgttacg gcaacgactg taccggggaa gcggaccaag aattgctcca gccattcgac
     3061 cgattccgca tccaagtggt tggtcggctc gtccagcagc agcatatcgg gtttgctcaa
     3121 caagagtttg cacaaggcaa cgcggcgttt ttcaccgccg gacagattgc cgattttggc
     3181 atcccattcc ggcaggcgca gcgcgtcggc ggcgatttcc aattcgtgtt ccgcaccgcc
     3241 gcccgtggac gaacctgccg caataatcgc ttccaagcgg ccctgctctt ctgccaacgc
     3301 gtcaaaatcc gcatcaggat tggcgtactc ggcatacact tcctccaaac gtttctgcgc
     3361 ggcagccact tcgcccaaac cgctttccac ttcctcgcgc acggtttttt ccggatcaag
     3421 ctcaggctct tgcggcaggt agccgatttt gatgccgccc atcggcacgg cttcgccctc
     3481 aaattcctta tccacgcccg ccataatccg cagcacggtg gacttgcccg cgccgttcaa
     3541 accgagcagg ccgattttcg cgccggggaa gaaagaaagg gaaatatctt taatgatggt
     3601 tttctgcggc ggcacaacct tgctcacgcg cagcatagaa tagacgtatt gttgggacat
     3661 ggttttctcg ttttcatcaa acaaatttca gacggccatt ttaaccgata atttgattta
     3721 agccagttta tccgcgaacc ggtattgcca aaatcgggca ggattcataa aatccgctta
     3781 tccctttgaa attatataga caaaaaaata ataatgatag gggatcgccg ccccggcaac
     3841 catttcggat tttccaaag
//
LOCUS       DAXIDM010000141         3646 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000141 DAXIDM010000000
VERSION     DAXIDM010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3646
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.141"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..106)
                     /locus_tag="ACFOAE_001899"
     CDS             complement(<1..106)
                     /locus_tag="ACFOAE_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006249760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6885315.1"
                     /translation="MRKSRLSRYKQNKLIELFVTGVTARTAAELVGVNK"
     gene            365..1837
                     /gene="pyk"
                     /locus_tag="ACFOAE_001900"
     CDS             365..1837
                     /gene="pyk"
                     /locus_tag="ACFOAE_001900"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFC6885316.1"
                     /translation="MNQTSRDLTRISHNTKIVATLGPGSNNVELLEDMIRVGGLNVVR
                     FNFSHGTPEFHQENARIVREAAKRAGQEIAIIADLQGPKIRVGKIAGGGIELNKGETL
                     VLDAALEGEGTREAVGLDYRDLPDDVAAGDVLWLDDGLLTLTVESVEGSRIITRVENS
                     HVLKSNKGINKRGGGLSAGALTEKDFRDLKTAIAIGCDYLAISFVKSAEDLHIARAKV
                     EEEMKGSTAVRPGLVSKIERVEAIENLDEIILAGDGIMVARGDLAVEVGHAAVPALQK
                     RMIRRARELRRFSITATQMMESMITNPVPTRAEVSDVANAVLDGTDAVMCSAETAVGA
                     YPFETVSQMAIICAAAEKEQDSLNGVAEQVEYPEAVSTNLAVAGGAVSVARAVHAKAI
                     VALTESGSTAFEISRHNITLPIFALTPSVSAQRRMAMYRGVRPLILATSTDHDTALNE
                     VETMLVEHNILHSGDQYIITSGSQMRESGSTNTLEVLRVK"
     gene            2147..3547
                     /locus_tag="ACFOAE_001901"
     CDS             2147..3547
                     /locus_tag="ACFOAE_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpP1/FadL family transporter"
                     /protein_id="HFC6885317.1"
                     /translation="MTPSALKKTVLLLGTAFAAASAQASGYHFGTQSVNAQSTANAAA
                     AEAADASTIFYNPAGLTKLNSSQISVNANIVLPSIHYEADSATDFTGLPVQGSKSGKI
                     TKTTVAPHIYGAYKVNDNLTVGLGVYVPFGSATEYEKDSVLRHNINKLGLTSIAVEPV
                     AAWKLNDRHSFGAGIIAQHTSAELRKYADWGIKSKAEILTAKPPKPNGVAEAAKIQAD
                     GHADVKGSDWGFGYQLAWMWDINDRARVGVNYRSKVSHTLKGDAEWAADGAAAKAMWS
                     TMLAANGYTANEKARVKIVTPESLSVHGMYKVSDKADLFGDVTWTRHSRFDKAELVFE
                     KEKTIVNGKSDRTTITPNWRNTYKVGFGGSYQISEPLQLRAGIAFDKSPVRNADYRMN
                     SLPDGNRIWFSAGMKYHIGKNHVVDAAYTHIHINDTSYRTAKASGNDVDSKGASSARF
                     KNHADIIGLQYTYKFK"
BASE COUNT          941 a         1092 c          911 g          702 t
ORIGIN      
        1 ttttattaac gcctactaac tctgctgccg ttcttgcagt tacacctgtg acaaacagct
       61 caatgagttt attttgttta taccggctta gacgactttt tctcataggg ataattctaa
      121 cttaatttga atttccctag ttatctagga cagccccaaa ataaatttag cctaagtcat
      181 aaaaccgtgt aattttgcac caaaaaaggc ggtttgcagg taaaatatca aactattaat
      241 ttaaatcata tttttacaga atattccgcc gcgttcatca aatggcatca aaccggttcc
      301 aaatttctgt aattttgcaa caaaataccg caaaacaccc gattgagacc gaaaggactt
      361 tcatatgaac cagacaagcc gcgatctgac ccgcatcagc cacaacacca aaatcgtcgc
      421 cacccttggg ccgggcagca acaacgtaga actgttggaa gatatgatcc gcgtcggcgg
      481 cctgaacgtc gtccgcttca acttcagcca cggcacgccc gaattccatc aggaaaacgc
      541 ccgcatcgtg cgcgaggcgg caaaacgcgc cggacaggaa atcgccatca ttgccgacct
      601 gcagggcccg aaaatccgcg tgggcaaaat cgccggcggc ggcatcgaat tgaacaaagg
      661 cgaaacgctg gtactggatg ccgcgctcga aggcgaaggc acgcgcgagg cggtcggttt
      721 ggactaccgc gacctgcccg acgacgttgc cgcaggcgat gtcttgtggc tggacgacgg
      781 cctgctgacc ctgaccgtgg aatccgtcga aggcagcagg attatcacaa gggtggaaaa
      841 cagccacgtc ctgaaaagca acaagggcat caacaaacgc ggcggcggtc tgtccgcagg
      901 cgcgttgacc gaaaaagact tccgcgacct gaaaaccgcg attgccatcg gttgcgacta
      961 tctcgccatc agctttgtga aatccgccga agatttgcac atcgcgcgcg ccaaagtcga
     1021 agaagaaatg aaaggcagca cggccgtgcg ccccggtttg gtttccaaaa tcgaacgcgt
     1081 agaagcgatt gaaaaccttg atgaaatcat cctcgccggc gacggcatta tggttgcacg
     1141 cggcgacttg gcggtcgaag tcggacacgc cgccgtcccc gccctgcaaa aacggatgat
     1201 ccgccgcgcc cgcgagttgc gccgcttcag cattacggcg acgcaaatga tggaatcgat
     1261 gattaccaac cccgtgccga cccgcgcgga agtcagcgat gtggcaaacg cggtattgga
     1321 cggcaccgat gcggtgatgt gttccgccga aaccgccgtc ggcgcgtatc cgtttgaaac
     1381 cgtcagccaa atggcgatta tctgcgcggc tgcggaaaaa gagcaggatt cgctcaacgg
     1441 cgttgccgaa caggtcgagt atcccgaagc ggtcagcacc aacctggcgg ttgccggcgg
     1501 tgcggtcagc gtggcgcgcg cggttcacgc caaagccatc gtcgccctga ccgaaagcgg
     1561 ttcgaccgcc tttgaaatca gccgccacaa catcaccctg ccgattttcg cgctgacccc
     1621 gagcgtttcc gcccaacgcc gtatggcgat gtaccggggc gtgcgcccgc tgattttggc
     1681 aaccagcacc gaccacgaca cggcgttaaa cgaagtcgaa accatgctgg tggaacacaa
     1741 catcctgcat tccggcgacc aatacatcat taccagcggc tcgcaaatgc gcgaatccgg
     1801 ttcgaccaat acgctggaag tgctgcgcgt caaataatcc gccctgagtg gaaaatgccg
     1861 tctgaagtcg atgcccgagg cttcagacgg cattttttgc ggcggcgcgg cggttcgggc
     1921 aaactctgaa aaaattgtgc aaatccggca acatcggata aaatcgagta cctatactaa
     1981 agcgaaacaa ggcatttccg actgcctttt ttatagtgga ttaaatttaa accagtacgg
     2041 cgttgccttg ccgtactatc tgtactgtct gcggcttcgt cgccttgtcc tgatttttgt
     2101 taatccacta tatttatcca ccgtccgcct ttttacggaa accgaaatga ccccttccgc
     2161 actgaaaaaa accgtcctgc tgctcggcac tgcctttgcc gccgcatccg cacaagcctc
     2221 cggctaccac ttcggcacac agtcggtcaa cgcgcaaagc acggcaaatg ccgccgccgc
     2281 agaagccgcc gacgcatcga ccatcttcta caaccctgcc ggcctgacca aactcaacag
     2341 cagccagatt tccgtcaacg ccaacatcgt gctgcccagc attcattatg aggcggattc
     2401 cgccaccgac tttaccgggc ttcccgtcca aggttcgaaa agcggcaaaa tcaccaaaac
     2461 cacggtcgcg ccccacatct acggcgcata caaagtcaac gacaatctga ccgtgggctt
     2521 gggcgtgtac gtccccttcg gctctgccac cgaatacgaa aaagattccg tgttgcgcca
     2581 caacatcaac aaactcggtc tgaccagcat cgccgtcgaa cctgtcgccg catggaaact
     2641 caacgaccgc cattccttcg gcgcaggcat catcgcccaa catacttccg ccgaactgcg
     2701 caaatatgcc gactggggga ttaagagtaa agcagagata ttgacggcaa aaccgcccaa
     2761 acctaacggt gtagccgaag ctgcaaaaat tcaggccgac ggacacgccg atgtcaaagg
     2821 cagcgattgg ggcttcggct accaactggc gtggatgtgg gacatcaacg accgcgcgcg
     2881 cgtgggcgtg aactaccgtt ccaaagtctc gcacacgctc aaaggcgatg ccgaatgggc
     2941 ggcagacggc gcggcggcga aagcaatgtg gagtacgatg cttgcagcaa acggctacac
     3001 ggcgaatgaa aaagcccgcg ttaaaatcgt tacgcctgag tctttgtccg tacacggtat
     3061 gtacaaagtg tccgataaag ccgacctgtt cggcgacgta acttggacgc gccacagccg
     3121 cttcgataag gcggaactgg tttttgaaaa agaaaaaacc atcgtcaacg gcaaatccga
     3181 ccgcaccacc atcaccccca actggcgcaa cacctacaaa gtcggcttcg gcggttctta
     3241 tcaaatcagc gaaccgctgc aactgcgcgc cggcatcgct tttgacaaat cgcccgtccg
     3301 caacgccgac taccgcatga acagcctgcc cgacggcaac cgcatctggt tctccgccgg
     3361 catgaaatac catatcggca aaaaccacgt cgtcgatgcc gcctacaccc acatccacat
     3421 caacgacacc agctaccgca cggcgaaggc aagcggcaac gatgtggaca gcaaaggcgc
     3481 gtcttccgca cgtttcaaaa accacgccga catcatcggc ctgcaataca cctacaaatt
     3541 caaataaacg gcccgccgtt tgattgtaga aatgccgtct gaaacagatt tccgtttcag
     3601 acggcattgt tttaggcgcg atttatagtg gattaacaaa aatcag
//
LOCUS       DAXIDM010000142         3641 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000142 DAXIDM010000000
VERSION     DAXIDM010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3641
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.142"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..66
                     /locus_tag="ACFOAE_001902"
     CDS             <1..66
                     /locus_tag="ACFOAE_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885318.1"
                     /translation="KQGMYPHNWGGGNADFSIGYD"
     gene            103..363
                     /locus_tag="ACFOAE_001903"
                     /pseudo
     CDS             103..363
                     /locus_tag="ACFOAE_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(502..741)
                     /locus_tag="ACFOAE_001904"
     CDS             complement(502..741)
                     /locus_tag="ACFOAE_001904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885319.1"
                     /translation="MLPTRKTARKIQARHIALPFSGKPQFYRPQERLSKQAQATPPGH
                     FRFHRLSVVRIMQQHHQRITLFGRQQAETFAKIVC"
     gene            801..1424
                     /locus_tag="ACFOAE_001905"
     CDS             801..1424
                     /locus_tag="ACFOAE_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HFC6885320.1"
                     /translation="MKKPTDTLPVNLQRRRLLCAAGALLLSPLAHAGAQREETLADDV
                     ASVMRSSVGSVNPPRLVFDNPKEGERWLSAMSARLARFVPEEEERRRLLVNIQYESSR
                     AGLDTQIVLGLIEVESAFRQYAISGVGARGLMQVMPFWKNYIGKPAHNLFDIRTNLRY
                     GCTILRHYRNLEKGNIVRALARFNGSLGSNKYPNAVLGAWRNRWQWR"
     gene            1535..2917
                     /locus_tag="ACFOAE_001906"
     CDS             1535..2917
                     /locus_tag="ACFOAE_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFC6885321.1"
                     /translation="MARDNRIQMFPHEWRASTTLSGVYALRMLGMFLVLPVLAVYAAS
                     LPGAEGNKTLVGLAMGIYGLTQALLQLPLGIASDKFGRKKTIYAGLVVFAAGSFLAAA
                     ADTLPMLVAARAIQGAGAVSAAVTALLADLTRDGVRTRAMAMIGLSIGLTFSVSLVVA
                     PVIADAVGVRGLFMLTGILTVISIGVVAWMTPDPEVSKLHEDTQAQPSRIGEVLKNRR
                     LLTLDFGIFALHAAQMALFTALPFAMTQLGLEKIQHWKVYLPSTITGLVVMVPLIIVG
                     ETRNKLKQVFVLGIVCIAAAQLGLLSGMRSVGLITAYLVVYFIGFNVLEASLPSMVSK
                     IAPSDLKGTAMGVYNTMQSLGLFAGGAAGGLLFQKYGFSGVFAFCSILMLLWLVIAVL
                     SPAPKPVKNLSYPVGGVWQGNQEGLYRALSELEGVEDIGFSFDGQTVYLKVLQKGFDQ
                     AAAEKIITGV"
     gene            2921..3445
                     /locus_tag="ACFOAE_001907"
     CDS             2921..3445
                     /locus_tag="ACFOAE_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003710541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFC6885322.1"
                     /translation="MSLNKVILIGRLGRDPEVRYMPNGEAVCNFSVATSETWNDRNGQ
                     RVERTEWHNITMYRKLAEIAGQYLKKGGLVYLEGRIQSRKYQGKDGIERTAYDIVANE
                     MKMLGGRNENSGGAPYEEGYGQSQEAYQRPAQQSRQPASDAPSHPQEAPAAPRRQPVP
                     AAAPVEDIDDDIPF"
BASE COUNT          775 a          952 c         1059 g          855 t
ORIGIN      
        1 aaacagggta tgtatccgca taattggggt ggcggcaatg cggacttttc tattggatac
       61 gattgaagta atgtcggatt cgagaatccg acctacggaa aactgaaaga gcatcggctg
      121 caggacggca ttatgcgcaa agcctgccgt aaccgtccgc tgacggaaaa tcaaaccaag
      181 cgtaaccgat atttgtcgaa gacccgttat gtggttgaac aaagcttcgg tacgctgcac
      241 cgtaaattcc gctacgctcg ggcagcctat ttcggactga ttaaagtgag tgcgcaaagc
      301 catctgaagg cgatgtgttt gaacctgttg aaagccgcca acaggctgag acctttgcaa
      361 taacataggt tactaaaatt ttatgctcaa tctcattttc aaaatgcaaa acttttctga
      421 tttttcccac tttttgctca atattaggaa ggttttaggc aattgaaaat tttttggcgc
      481 atttttatgc gtcaaatttc gttaacagac tatttttgca aaggtctccg cctgctgccg
      541 cccgaaaagc gtgatgcgct gatggtgctg ctgcataatc cggacgacgg ataaccggtg
      601 aaaacggaaa tgcccgggcg gtgttgcctg tgcctgtttg gacaagcgtt cttgagggcg
      661 gtagaattga ggtttgcccg aaaagggcag ggcgatatgc cgcgcttgga ttttgcgcgc
      721 ggtttttcgc gttggaagca atcattgtct gtttgaatat ttaatgccgt ctgaaacgtc
      781 cggacgcgcc cccgttccct atgaaaaaac cgaccgatac cctacccgtt aatctgcaac
      841 gccgccgcct gttgtgtgcc gccggtgcgt tgttgctcag tcctctggcg cacgccggcg
      901 cgcaacgtga ggaaacgctt gccgacgatg tggcttccgt gatgaggagt tctgtcggca
      961 gcgtcaatcc gccgaggctg gtgtttgaca atccgaaaga gggcgaacgt tggttgtctg
     1021 ccatgtcggc acgtttggca aggttcgtcc ccgaggagga ggagcggcgc aggctgctgg
     1081 tcaatatcca gtacgaaagc agccgggccg gtttggatac gcagattgtg ttggggctga
     1141 ttgaggtgga aagcgcgttc cgccagtatg caatcagcgg tgtcggcgcg cgcggcctga
     1201 tgcaggttat gccgttttgg aaaaactaca tcggcaaacc ggcgcacaac ctgttcgaca
     1261 tccgcaccaa cctgcgttac ggctgtacca tcctgcgcca ttaccggaat cttgaaaaag
     1321 gcaacatcgt ccgcgcgctt gcccgcttta acggcagctt gggcagcaat aaatatccga
     1381 acgccgtttt gggcgcgtgg cgcaaccgct ggcagtggcg ttgattttga acccgcgccg
     1441 caaccgaaat acggcgaatc ctgtataatc cgaaaatctg ttcactggaa gttcagacgg
     1501 cattgcaact gttaatgccg tctgaaaaaa tatgatggca agagacaacc gcatccaaat
     1561 gtttccgcac gaatggcgcg ccagtacgac gctttccggc gtgtacgcgc tgcgtatgct
     1621 gggtatgttc ctcgtgctgc ccgtattggc ggtgtatgcc gcctcgctgc ccggcgcgga
     1681 aggcaacaaa acgctggtcg ggctggcaat gggcatttac gggctgacac aggctctgct
     1741 gcaactgcct ttgggcatcg cttccgacaa gttcgggcgc aagaaaacca tttatgcggg
     1801 actggtcgtg tttgcggcgg gcagctttct tgccgccgcc gccgatacgc tgcccatgct
     1861 ggtcgccgca cgcgccatac agggtgcagg ggcggtcagt gcggcggtta ccgcgctgct
     1921 ggcggatttg acgcgcgacg gcgtacgtac ccgcgcaatg gcgatgatcg gtttgagtat
     1981 cggtttgacg ttttcggtca gcctcgtcgt tgcccccgtg attgccgacg cggtcggcgt
     2041 tcgcggactg tttatgctga ccggcattct gaccgtcatc agcatcggcg tggtggcgtg
     2101 gatgactccc gatcccgaag tttccaagct gcacgaagat acgcaggcgc agccttcgcg
     2161 cataggcgaa gttttgaaaa accgtaggct gctgacgctt gatttcggca ttttcgccct
     2221 gcacgccgca caaatggcat tgtttaccgc gctgcctttc gcgatgaccc agctcggttt
     2281 ggaaaaaata cagcattgga aagtctatct gccttcgacc attacgggct tggtggtgat
     2341 ggttccgctg attatcgtcg gcgagacgcg caacaagctt aagcaggttt ttgttttggg
     2401 tatcgtctgt attgcggcgg cgcagctcgg tttgctgtcc ggtatgcgct cggtaggctt
     2461 gattaccgct tatttggttg tttactttat cggttttaat gtgttggaag cgagcctgcc
     2521 gtctatggtt tccaaaatcg cgccgtccga cctgaagggt acggcgatgg gcgtgtacaa
     2581 cacgatgcag tcgctcggac tgtttgccgg cggcgcggca ggcggtttgc tgtttcaaaa
     2641 atacggcttt tccggcgtgt ttgccttttg cagtatattg atgctgctgt ggctggtaat
     2701 tgccgtttta tcgcctgcgc ccaagcccgt caaaaacctc agttaccctg tcggcggcgt
     2761 gtggcagggc aatcaggaag ggttataccg cgccttgtcg gagcttgagg gtgtggaaga
     2821 catcggtttc agtttcgacg ggcagaccgt ctatctcaaa gtgttgcaga agggtttcga
     2881 tcaggctgcc gctgaaaaaa tcatcacagg agtttaaaaa atgtcattga acaaagtcat
     2941 cctcatcggc cgcctcggac gcgatcccga agtgcgctat atgcccaacg gcgaggcggt
     3001 ttgtaatttc agcgtcgcca ccagcgaaac ttggaacgac cgcaacggcc aacgtgtaga
     3061 gcgtactgag tggcacaaca tcaccatgta ccgcaaactg gcggaaattg ccgggcaata
     3121 cctcaaaaaa ggcgggctgg tttatctgga aggcagaatc caaagccgca aataccaagg
     3181 caaagacggc atcgaacgca ccgcttacga tattgtcgcc aacgaaatga aaatgttggg
     3241 cgggcgcaat gaaaacagcg gcggtgcgcc ttacgaggaa ggttacggtc agagtcagga
     3301 ggcttaccaa cgccccgcgc agcaaagccg gcagcccgcc tccgacgcgc cgtcccatcc
     3361 ccaagaagca ccagccgcgc cgcgccgcca acccgtgcct gccgccgccc cggtcgagga
     3421 cattgacgac gatatcccgt tctgaatttt acggccggac atcctcgcgg agggaaatca
     3481 taaaggacgg agaaacctta aaccttacgg ggcagggttt ctcttttttg catttgggcc
     3541 ggcttgttgc cgccctttgc gttgggcgga acgttgcgat tgcgccgttc gggcgttttg
     3601 aggcagtgat gcctgccgca cgtccccgct gttttcagac g
//
LOCUS       DAXIDM010000143         3570 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000143 DAXIDM010000000
VERSION     DAXIDM010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3570
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.143"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            181..960
                     /locus_tag="ACFOAE_001908"
     CDS             181..960
                     /locus_tag="ACFOAE_001908"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004324 - ferredoxin-NADP+ reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP reductase"
                     /protein_id="HFC6885323.1"
                     /translation="MAASPEAKFTEEKILWVKHHTPKLITFAISRPESYRFKAGQFSR
                     LGFYEGEGFIWRAYSIVSAEYADTLEYFAVLIQDGPMSARFAKMQQGDTILLDKNATG
                     FLLPERFPDGKDLVMLCTGSGIAPFLSILEQPEIRQRFDTVNLIHSVSFPEELIFNDR
                     LAALSEHPLVGEYGHSFRFIPVTTRAANSDGLGGKRIPELLKNGSIEQALHTKFTPES
                     TRFMICGNPEMVKDTFQTLLDMGYAMHRNRIPGQIMMENGF"
     gene            complement(1160..2545)
                     /locus_tag="ACFOAE_001909"
     CDS             complement(1160..2545)
                     /locus_tag="ACFOAE_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFC6885324.1"
                     /translation="MIVTSRWPLLEKAFLRFGMPVAVVDLESTGGNLYEDRVTEVALL
                     KFEQGRAERYEWLVNPQKPIPKFVAELTGISDGMVADAPVFAEIAGELFSVLKGCVLI
                     AHNSRFDYTFLKHEFHRAGIGFSSPALCSVQLSRCLYPQFYKHSLDSIIERLGIVVED
                     RHRAMADVSALCDYLEYSLSEHGVEEWIRQCFRLMNPKPLPAALPERLREQLYGLPDG
                     MGVLACFDGGGKVNYIGTFERVYSEVSALLDSGKAPFDWCNTEEVRFFPALGRLHAHK
                     VKAELVRHYGVDCYVSAKNLLKTFTTVRFEKGSDGMLNAKTAALKNGVADNPPTGLFA
                     NKKAARRALSSWAETYGLCPASAGILPDGYAEDEPCPVYVSGRCDKACGRSDEQVLAF
                     AHKLPILDWGKMHEVEITETDPLTGEKVVLHGMGGALEMDDGFWYFDKDLPDAFKAKF
                     KTDRKNIKEIG"
     gene            2663..2739
                     /locus_tag="ACFOAE_001910"
     tRNA            2663..2739
                     /locus_tag="ACFOAE_001910"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2697..2699,aa:Arg,seq:acg)
     gene            2757..2831
                     /locus_tag="ACFOAE_001911"
     tRNA            2757..2831
                     /locus_tag="ACFOAE_001911"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2790..2792,aa:Glu,seq:ttc)
     gene            complement(3007..3348)
                     /locus_tag="ACFOAE_001912"
     CDS             complement(3007..3348)
                     /locus_tag="ACFOAE_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003712388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885325.1"
                     /translation="MMIKYTSIKDIVEYGLDAISDKEKITMNLKDFLYIRRVLEEYMR
                     YLHNPDHYPDIEAIQNFLGDASSGGGFECLSTAIYNKVYKVDLPAKIEKMIDDGLFEH
                     PLYPSYYKKNE"
BASE COUNT          993 a         1015 c          654 g          908 t
ORIGIN      
        1 aggattaagg gggtatttgg gtagaattag gcggtatttg gggcgaaaac agccgaaaac
       61 ctgtgtttgg gtttcggctg tcgggaggga aaggaatttt gcaaaggtct cagaccgtca
      121 atgcggaaaa aaacacccaa attggctata atcccgacaa acacactcaa ggacaacaac
      181 atggcagcct cgcccgaagc aaaattcact gaagaaaaaa ttttgtgggt caaacaccac
      241 acgccgaaac tcatcacttt cgccatcagc cgtcccgaat cctaccgttt taaagccgga
      301 cagttctccc gactcggttt ctacgaagga gaaggtttca tttggcgtgc ctactccatc
      361 gtttccgcag aatatgccga cacgctcgaa tattttgccg tactcatcca agacggtccc
      421 atgtcggccc gtttcgccaa aatgcaacag ggcgacacca tcctgctgga taaaaatgcc
      481 accggcttcc tcctgcccga acgcttcccc gacggcaagg atttggtgat gctctgcacc
      541 ggctccggca tcgccccctt cctttccatt ctcgaacaac ccgaaatccg gcagcgtttc
      601 gataccgtca acctgataca ttccgtatct tttcccgaag aattgatttt caacgaccgg
      661 ctcgccgccc tttccgaaca ccctctggtc ggcgaatacg gacactcgtt ccgtttcatc
      721 cccgtaacca cccgcgccgc caattccgac ggattgggcg gcaaacgtat tcccgaactc
      781 ttaaaaaacg gcagcatcga acaggcactg cataccaagt tcacccccga atccacacgg
      841 tttatgattt gcggcaaccc ggaaatggtc aaagacactt tccaaacgct gcttgacatg
      901 ggttacgcca tgcaccgcaa ccgcattccc ggtcaaatca tgatggaaaa cggcttctaa
      961 aaaccaccct gcttgtccga tgcctcggac gggcaaaccg gcacgacacg caaaccgcgt
     1021 cggcaaaaat gccgtctgaa gccttcagac ggcattttcg gatacataca aacggcaaca
     1081 cattccaacc caaaccgatt aggcaatcaa tacgaacggc tgtttacata cttaccggct
     1141 ttcaccaacc ggtatcgatt taaccgattt ccttaatatt tttcctgtcc gttttaaact
     1201 tcgccttaaa cgcatccggt aaatctttat cgaaatacca aaacccgtca tccatttcca
     1261 atgcgccgcc cattccatgc agaacaactt tttcccccgt taaaggatcg gtttcggtaa
     1321 tttccacctc atgcattttt ccccaatcca aaataggcaa cttgtgtgca aacgccaaaa
     1381 cctgttcgtc agaacggccg cacgccttat cgcatcggcc tgaaacatat acgggacaag
     1441 gctcatcctc tgcataacca tccggaagga taccggctga ggcaggacac aatccgtatg
     1501 tttccgccca cgacgacaaa gcccgtctcg ccgccttttt attggcaaat aatccggtag
     1561 gcggattatc cgccacaccg tttttcaaag ccgctgtttt cgcattcaac atgccgtctg
     1621 aacctttttc aaacctgacg gtcgtaaatg ttttaagcag atttttggca gatacgtaac
     1681 aatccacccc ataatgcctg accaattccg ctttaacctt atgggcatgc agcctgccca
     1741 atgcgggaaa aaaacggact tcctccgtat tgcaccaatc aaacggggct tttccggagt
     1801 ccaataaagc cgaaacctcg ctatataccc gttcaaacgt accgatgtaa tttactttcc
     1861 ctccgccgtc gaaacaagcc agcaccccca taccgtcagg caaaccgtac aactgttccc
     1921 tcaaccgttc gggcagcgcg gcaggcaacg gtttcggatt catcaaacgg aaacactgcc
     1981 taatccactc ctcaaccccg tgttccgaca ggctgtattc caaataatca cacaatgccg
     2041 atacatccgc catcgcacga tgcctgtctt ccacaacaat ccccaacctt tcgatgatac
     2101 tgtccagact gtgcttgtaa aattgcggat acagacaccg ggacaactgc acactgcaca
     2161 aagcaggcga tgaaaatccg atacccgcac gatgaaactc atgctttaaa aacgtatagt
     2221 cgaaacggct gttatgtgca atcaacacac aacccttcaa taccgaaaac aactcgccgg
     2281 caatctctgc aaaaacaggt gcgtcggcaa ccatgccgtc tgaaatcccc gtcagctccg
     2341 ccacaaactt cggaataggt ttttgaggat tgaccagcca ttcatacctc tccgcccttc
     2401 cctgctcaaa cttgagcaaa gccacttcgg ttaccctgtc ttcatacaga ttgccgcccg
     2461 tcgattccaa atcaaccacg gcaacaggca ttccaaaccg taaaaatgcc ttttccagca
     2521 agggccaacg ggaagtaaca atcattttat tctctttaaa ttcaaacaac aaaccgatat
     2581 tttacacttt tgaggcattt catccaacaa aacaattgac agaatccgat gattacccta
     2641 aaattcaaat ctttcttgca gcgcacccgt agctcagttg gatagagtat ctggctacga
     2701 accagagggt cgggcgttcg aatcgctccg ggtgcgccag taagaaaata caatatgcgc
     2761 ccatcgtcta gcggttagga catcgccctt tcacggcggt aaccggggtt cgattccccg
     2821 tgggcgtgcc aaattccaaa tcccccgaaa taatccctcg gggatttttt attgcctcgg
     2881 caactcgtta ccatagttaa aatttaacaa gcactatttt cactttttat cctttcctac
     2941 aacttcgaat ttacgtatcc acataaattt atattttcta caatttcaat actatccaat
     3001 tattgcttat tcatttttct tatagtaact gggatataga gggtgttcaa ataaaccatc
     3061 atcaatcatt ttctcaatct tcgccggcaa atcaacttta tatactttgt tataaatagc
     3121 tgtgcttaaa cattcaaatc cgcctcccga agaagcatca cctaaaaaat tttgaattgc
     3181 ttctatatcg ggataatgat caggattatg tagataacgc atatattcct ctaaaactcg
     3241 tctaatgtat agaaagtctt tcaggttcat tgttattttt tccttatcag aaatagcatc
     3301 taatccatat tcaacgatat cttttatact tgtatatttt atcatcatct ttacctaccc
     3361 ccttcatcag aatctcagac gtaatcgaat catattcaaa cctttgccgt gcaaaccgat
     3421 atcacataac cggatgcggt gtccgttcaa cattttaccc gattgaaacg cctgatatat
     3481 cgcaccccat caaaggggca ttgcttttct taacaatccc ctttgacagg gcttttttat
     3541 gccatcatca aatttatagt ggattaactt
//
LOCUS       DAXIDM010000144         3550 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000144 DAXIDM010000000
VERSION     DAXIDM010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3550
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.144"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            191..1726
                     /locus_tag="ACFOAE_001913"
     CDS             191..1726
                     /locus_tag="ACFOAE_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HFC6885326.1"
                     /translation="MSDSKTKERATFGTRRAFMIAAIGSAVGLGNIWRFPYIAFENGG
                     GAFILPYLVALLTAGIPLLLLDYAIGHRYRGSAPLAFRRLGRWFEPVGWWNVMTNIVI
                     CIYYAVIIGWAASYTYYSVNAAWGADPQGFFFKDFLQMAGPEALGLDFVGKVAGPLAG
                     VWVFTAAIMALGVQKGVARASSFFMPLLLVMFLIMVGISLTLPGAAKGLDALFTPDWS
                     KLADSKVWVAAYGQIFFSLSICFGIMVTYSSYLKKKTDLGGTGLVVGFANSSFELLAG
                     IGVFAALGFMAQAGGKAVNEVASGGIGLAFIAFPTIINQAPMGWLIGILFFGSLVFAG
                     VTSMISILEVIVAAIQDKLNIGRVNATLLVCIPMGIVSTLLFGTATGLPVLDVMDKFV
                     NTYGIVAAGFVYVAAIIISGRLPELRKHLNALSSIRIGGLWTVCVVVTVVMLGYMLFK
                     DTSGLMEKNYEGYPDGFLSIFGWGMSAALVVFGLLLSLLPWKHGQDFNVKDEHEHEQG
                     EEK"
     gene            1723..1815
                     /locus_tag="ACFOAE_001914"
     CDS             1723..1815
                     /locus_tag="ACFOAE_001914"
                     /inference="COORDINATES: protein motif:HMM:NF033493.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine/alanine import family NSS transporter
                     small subunit"
                     /protein_id="HFC6885327.1"
                     /translation="MSTSAIVMMIVSIVIIWGGLLLSLLRLPNE"
     gene            complement(1851..3095)
                     /gene="lysA"
                     /locus_tag="ACFOAE_001915"
     CDS             complement(1851..3095)
                     /gene="lysA"
                     /locus_tag="ACFOAE_001915"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014575588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFC6885328.1"
                     /translation="MTLFCEQVPYPRLAEAFGTPLYVYSQSALTEAFEHYQTAFAELS
                     PLVCYAVKANGNLSIIKHFASLGSGFDIVSGGELARVLAAGGDAAKTIFSGVGKSEAE
                     IEFALNAGVKCFNMESIPEIDRIQKVAARLGKTAPVSLRVNPDVDAKTHPYISTGLKA
                     NKFGIAYADALEAYRHAAQQPNLKIIGIDCHIGSQLTDLSPLVEACERILILVDALAA
                     EGIVLEHLDLGGGVGIVYKDESVPDLGAYAQAVQKLIGTRRLKLILEPGRSLVGNAGS
                     LLTRVEFVKHGEEKNFVMVDAAMNDLMRPALYDAYHHIEAVETKNISPLTANIVGPIC
                     ETGDFLGKDRTIACEEGDLLLIRSAGAYGASMASNYNARNRAAEVLVNGGGYKLIRRR
                     ETLEQQMANELACLQAEHQNAV"
     gene            complement(3106..3276)
                     /locus_tag="ACFOAE_001916"
     CDS             complement(3106..3276)
                     /locus_tag="ACFOAE_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013449575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFC6885329.1"
                     /translation="MKYGVFFAAATALLLSACGYKGDLYLPKEGDKARFGVIQTGLQL
                     QSKPQSAPPTQK"
     gene            3347..>3550
                     /gene="cyaY"
                     /locus_tag="ACFOAE_001917"
     CDS             3347..>3550
                     /gene="cyaY"
                     /locus_tag="ACFOAE_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HFC6885330.1"
                     /translation="MMTESEFIRASEALFEHIEDQIDENGWDFDCRFAGNVLTIEAGD
                     GTQIIVNRHTPNQELWIAAKSGGY"
BASE COUNT          712 a          884 c         1021 g          933 t
ORIGIN      
        1 aaatttttcg ttttcaaacc ttcaccgctt gtcatcggcg ttaaattttt ttatgataag
       61 cacatagatt gtaaacaatc ggccacaagc cggtttgttt tttcagaaga cattatccct
      121 gtcagacgct gtttctatat attttgccta taacggcttg tttttaataa ataattcaag
      181 aggtatcaac gtgtctgatt ccaaaacgaa agaacgcgcc acattcggta cgcgccgcgc
      241 gtttatgatt gccgccatcg ggtccgccgt cggcttgggc aatatttggc gtttccccta
      301 tattgctttt gaaaacggcg gcggcgcgtt catcctgccc tatctggtcg cgcttctgac
      361 ggcgggcatt ccgctgctgc tgctcgatta tgccatcggc caccgttacc gtggttctgc
      421 gcccttggct ttccgccgcc tcggacgatg gtttgagccg gtcggctggt ggaacgtgat
      481 gaccaatatc gtcatctgca tctattacgc ggtaattatc ggttgggcgg caagctatac
      541 ctattattcg gtcaacgccg cctggggtgc ggatccgcag ggttttttct ttaaggactt
      601 cctgcaaatg gcgggcccgg aagccttggg tttggatttt gtcggcaaag tcgccggtcc
      661 tttggcgggc gtgtgggttt ttaccgccgc cattatggct ttgggcgtgc aaaagggcgt
      721 ggcgcgcgcc tcgtcgttct ttatgccgct gcttttggtg atgtttttga ttatggtcgg
      781 catttcacta accctgccgg gtgcggcaaa gggcttggac gcattgttta cgcccgactg
      841 gtcgaaactc gccgattcca aggtctgggt ggcggcatac gggcagattt tcttttcgct
      901 ttccatctgc ttcggcatta tggttaccta ttcttcttat ttgaagaaaa aaaccgactt
      961 gggcggaacg gggctggtgg tcggttttgc caacagcagc tttgaactgc tcgcgggcat
     1021 cggcgtgttt gccgcattgg gctttatggc gcaggcgggc ggtaaggcgg tcaacgaggt
     1081 tgcctcaggc ggcatcggtt tggcgtttat cgcctttccg accattatca accaggcacc
     1141 gatgggctgg ctgatcggca tattgttttt cggttcgctg gtattcgccg gcgttacgtc
     1201 gatgatttcc atccttgaag tgattgtggc ggcgattcag gacaagctga acatcgggcg
     1261 cgtcaacgcc acgctgctgg tctgcattcc gatgggcatt gtttccacgc tgctgttcgg
     1321 tacggcgacg gggctgccgg ttttggacgt gatggacaaa ttcgtcaaca cctacggcat
     1381 tgttgccgcc ggctttgttt atgttgccgc catcatcatc agcggcaggc tgccggaatt
     1441 acgcaagcac ctgaacgctt tgtcctccat ccgcatcggc ggcttgtgga cggtctgcgt
     1501 cgtggttacc gtcgtgatgc tcggctatat gctgtttaaa gataccagcg gcctgatgga
     1561 gaaaaattac gaaggttatc cggatggttt cctcagtatt ttcggctggg ggatgtcggc
     1621 ggcgttggtc gtgttcgggc tgctgctgtc gttgctgcct tggaaacacg gtcaggattt
     1681 caacgtcaaa gacgaacacg aacatgaaca aggagaagaa aaatgagtac ttccgccatt
     1741 gtgatgatga ttgtctcaat cgtgataatc tggggagggc tgctgctttc cctgttaagg
     1801 ctgccaaacg agtaagcctt tagagcgtta aaaatgccgt ctgaaccgct tcagacggca
     1861 ttttgatgtt cggcttgcag gcaggcgagt tcgtttgcca tttgctgttc taaggtttcg
     1921 cgtcggcgga tgagtttgta tccgccaccg ttaaccaaca cttccgccgc acggttgcgc
     1981 gcgttgtaat tgctcgccat actggctccg tatgcgcccg cgctgcggat aagcagcaaa
     2041 tcgccttctt cgcaggcgat ggtgcggtct ttgccgagga agtcgccggt ttcacaaatc
     2101 gggccgacga tgttggcggt cagaggcgag atgtttttgg tttcaaccgc ttcgatgtgg
     2161 tgataggcat cgtatagggc cggacgcatt aaatcgttca tcgccgcatc gaccatcaca
     2221 aagtttttct cttcgccgtg tttgacaaac tcgacgcgtg tcagcagcga acctgcgttg
     2281 ccgaccaggc tgcggccggg ctcaagaatg agtttcagac ggcgtgtgcc gatcagtttt
     2341 tgaaccgctt gggcatacgc gcccaaatcg gggacgcttt cgtctttgta aacaatgccg
     2401 acaccgccgc ctaagtccaa gtgttccaac acaatgcctt cggcggcaag cgcgtcaacc
     2461 aaaatcaaaa tgcgttcgca ggcttcgaca agcggactta agtcggttag ttgggagccg
     2521 atgtggcagt cgatgccgat gattttcaaa ttgggctgtt gtgcggcgtg gcggtaggct
     2581 tcgagcgcgt cggcgtaggc gatgccgaat ttgttggctt tcagacctgt ggagatgtag
     2641 ggatgggttt ttgcatcgac atcgggattg acgcgcaggg agacgggcgc ggttttgcct
     2701 aaacgcgcgg caactttctg aatacggtcg atttcgggga tgctttccat attgaagcat
     2761 ttcacgcctg cattcagcgc gaactcgatt tccgcctcgc ttttgcctac gcctgaaaat
     2821 atggtttttg ccgcgtcgcc gcctgccgcc aaaacgcgtg ccaattcgcc gccggacaca
     2881 atgtcaaaac cgctccccaa agaagcaaag tgtttgatga tgctcaggtt gccattggct
     2941 ttaaccgcat agcagacgag cggggagagc tcggcaaagg cagtttggta gtgttcaaat
     3001 gcttcggtca gcgcggattg gctgtacaca taaagcggtg tgccgaatgc ttcggcaagg
     3061 cgggggtagg ggacttgttc gcaaaatagg gtcatgtttt cgttttcatt tttgggttgg
     3121 tggagcggat tgcggtttgc tttgaagctg caaaccggtt tggattacgc cgaaacgcgc
     3181 cttgtcgcct tctttgggca ggtagaggtc gcctttgtaa ccgcaggccg agagcaggag
     3241 ggcggttgcc gccgcaaaaa atacgccgta tttcatcggt aaacttcctt cataagcgcg
     3301 aatgtggcaa gattcggcat cttaaacaaa aaacacgcaa aaagctatga tgaccgaaag
     3361 cgagtttatc cgcgcgagcg aagcattatt tgaacacatc gaagaccaaa tcgacgaaaa
     3421 cggctgggat ttcgactgcc ggtttgccgg aaacgtcctg accatcgaag ccggagacgg
     3481 cacgcaaatc atcgtcaacc gccacacgcc caatcaggaa ttgtggattg ccgccaaaag
     3541 cggcggctac
//
LOCUS       DAXIDM010000145         3523 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000145 DAXIDM010000000
VERSION     DAXIDM010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3523
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.145"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            655..1863
                     /locus_tag="ACFOAE_001918"
     CDS             655..1863
                     /locus_tag="ACFOAE_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFC6885331.1"
                     /translation="MSEAEYFSHFISNGNGKLLEIPQRRGRQDGVFIDWLSFTLHEDS
                     LLKVSGCPLVSDAEYMFVLSKKLEEILGFGITSRCKSKGNKFYDSMFRLGSEEVDYGE
                     VHYGGQRNTVLIELKGVGCNIANPGWELRLKQFLEDSLRPRITRVDLALDFFDGEYTP
                     EQALLDHDNGFFDNSNMRPKSEMVGTAWRREDGSGKTFYVGRKKNSRFVRVYEKGRQL
                     GDKESKWVRFEIQFNHGDMEIPLDILINQGSYFSGAFPICQKFKNMPNPERFDYRKKV
                     ANLTFQHKLRYAKNAVGKLINFMFDMGFDSDEIVRYLKADLGYPKGLEPEKYSLAGLK
                     ESLKFGFIHEQPDVDLEVELEELGIIKFKQSDKFDPDKRLFDPHHDVESERQYQLYLD
                     RMYDLHANQN"
     gene            1884..2195
                     /locus_tag="ACFOAE_001919"
     CDS             1884..2195
                     /locus_tag="ACFOAE_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885332.1"
                     /translation="MFNQTQTVTYPATFLGAKKFKGEIDGSNIDTCSVLVATPLPAQS
                     GNAVGFTAAQMKFGDSKNFSKLENLKYPCEVMVTVEMTSTGKGMVPSLIDFQVAEKPK
                     G"
     gene            2199..2399
                     /locus_tag="ACFOAE_001920"
     CDS             2199..2399
                     /locus_tag="ACFOAE_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885333.1"
                     /translation="MKFEERFIVQDLETHDFIYPDPFGDVGFTQNIKSAGQFESYEDA
                     LNAGINEIGGGFQIFQFFVKSE"
     gene            2637..2867
                     /locus_tag="ACFOAE_001921"
     CDS             2637..2867
                     /locus_tag="ACFOAE_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003694609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885334.1"
                     /translation="MNIVKKYAVKALLAAGIFTPAIVMADGFDASAIGTQVANVIMGF
                     VSMVSAVGMAAITVILAIQGFKMAWSMIKSVR"
     gene            2895..3194
                     /locus_tag="ACFOAE_001922"
     CDS             2895..3194
                     /locus_tag="ACFOAE_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885335.1"
                     /translation="MGYRVGINCFDTRLQADDYLLSSLPPTVTQDGKIIRPERVGDKW
                     ILNGKPVTLSYPKCSNYEQVKSGAYLGSMVLILFVVIYGFRLLINFLKDIGKVGA"
     gene            3313..>3523
                     /locus_tag="ACFOAE_001923"
     CDS             3313..>3523
                     /locus_tag="ACFOAE_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003696077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1132 family protein"
                     /protein_id="HFC6885336.1"
                     /translation="MNKPFITQAQLALYKYQPSSKYFGQSMALIASKEFEEFVRNVKE
                     YDVIECFSYFLNKRVTHNIWKIYFSD"
BASE COUNT         1053 a          600 c          829 g         1041 t
ORIGIN      
        1 aaaagcggga atccggttcg ttcggtttca gttttttagg tttcgggcaa cttctgaatc
       61 gtcattccca cgcaggtggg aatctaggtc tgtccgcacg ggaacttatg cgccgtcatt
      121 cccgcgaaag cggaaatcca gattcttcgg tacagaaact tatcggataa aacggtttct
      181 ttagattcta cgtcctagat tcccgcctta tatgatgcgc tctatcaaag gggcgcatta
      241 attttcttaa cattcccctt tgacagccaa gtgaaagggg cttttttatg tcagcagtaa
      301 atgtaatatt ttcctgttct tattggagaa tatttaaaaa atcagattct tgtgttttgt
      361 gtttttatca gttcagacat ggcgaaccgc ataaactcat taatcaagag aatttttcaa
      421 agctttatca ggcgttcgat tatatagatt cggttggttc gaattttcca gtgattatca
      481 caacggatgg ttgtggtctt ttttgttgat ctttaaaagt ttgtcaggat ttggctttcg
      541 gtcgttgacc gtcgtacgcg ctttagcgcg gaagacggga aacggctgaa agcccccccc
      601 ctgactaaca gggggggagc gaaataaaac aaatccctaa aggtactgaa caaaatgagt
      661 gaagcagaat atttttccca tttcatatct aacggcaatg ggaagttatt agaaattccg
      721 caacgtaggg gcaggcagga cggcgttttt atagattggt tgtcattcac actgcacgaa
      781 gattccttgc tgaaagtttc cggatgcccc ttagtttccg atgccgaata tatgtttgtt
      841 ttaagcaaaa aattggagga aatattaggg tttggcatca cgagcagatg caaatcgaag
      901 ggcaataaat tttacgattc gatgtttagg ttgggatcgg aagaagttga ctacggcgaa
      961 gtccattacg gaggtcagcg aaatacggtt ttaatcgaat tgaaaggtgt aggttgcaac
     1021 attgcaaatc caggttggga attgaggctt aagcagtttt tggaagattc attgaggccg
     1081 aggataacgc gggtagattt ggcacttgat ttttttgatg gggagtacac gccggaacag
     1141 gcacttttgg atcacgataa cggttttttc gataacagta acatgaggcc gaaatctgaa
     1201 atggttggaa cggcttggcg gagagaggac gggagcggca agacatttta tgtaggtcgc
     1261 aagaaaaatt ctcgttttgt gcgtgtttat gagaaaggca ggcagctagg cgataaagaa
     1321 agcaagtggg taaggttcga aattcagttt aatcatggag atatggaaat acctttggat
     1381 attctgataa atcaaggttc ttacttttca ggcgctttcc cgatttgtca gaaatttaaa
     1441 aatatgccga atccggaaag gttcgattac cgtaaaaaag tggctaattt aacttttcag
     1501 cataaattga gatacgcaaa aaacgcggtc ggcaaactga ttaatttcat gtttgatatg
     1561 ggttttgata gtgatgaaat tgtcagatat ctgaaggcag atttggggta tcccaaaggg
     1621 ctagaacctg aaaaatattc gttggccgga ttgaaggaat ctttgaaatt cggctttatc
     1681 cacgaacaac cggatgtaga tttagaggtt gaattggaag aactcggaat tatcaaattt
     1741 aagcaatcag ataaattcga tccggataaa aggcttttcg atccacatca cgatgtagaa
     1801 agtgagaggc aatatcagct ttatctcgac agaatgtatg atcttcatgc aaatcaaaat
     1861 taacctaaaa aggaaaaatt aatatgttta atcaaactca aactgtaact tatcccgcaa
     1921 cttttttagg agctaaaaaa ttcaaaggcg aaattgatgg ctctaatatc gacacttgtt
     1981 ccgtattggt tgcaacacct ttgccggcac agtcgggaaa tgctgttgga ttcacggcag
     2041 cacaaatgaa gttcggggac agtaagaatt tctcaaaatt agagaatctc aaatacccgt
     2101 gcgaagttat ggtaacggtt gaaatgactt cgacaggtaa gggcatggtt ccttcattaa
     2161 ttgattttca ggtggcagaa aagccgaaag gttgatttat gaaatttgaa gaacgtttca
     2221 tagttcaaga cttggaaacg catgacttta tttatcccga tcctttcggt gatgtggggt
     2281 ttactcaaaa tattaaatca gcaggtcaat ttgaaagcta cgaagatgcg ttgaatgcag
     2341 gcataaatga aataggcgga ggattccaga tatttcagtt cttcgtaaaa tcggaataaa
     2401 agaaaaacag gctcggcggg cggtctgtca acctttcaca aagcccgcaa caaaggaaaa
     2461 atatcatgaa aatgaacctt gcaacactaa ttatcggctg ggtggtctgt atgtttcttt
     2521 ttcttttcgc catcctctat tttatcggct aaaaacagga ttcgggaaag acttcgtccg
     2581 gatgaagcaa gtcaagaagt cgttttactt taaacatcaa aaaaaggaaa aaaacgatga
     2641 acatcgttaa aaaatatgct gtaaaagcat tgttggcagc cggtatcttc acaccggcta
     2701 ttgttatggc agatggcttt gatgcatccg cgattggtac gcaagtagcg aatgtaatca
     2761 tgggtttcgt gtcaatggtt tccgccgtgg gtatggcggc cattaccgtg attcttgcaa
     2821 tccaaggctt caaaatggct tggagcatga ttaaatctgt cagataaaca gagtgaagaa
     2881 aaaggggcgt ataaatgggc tatcgtgtcg gcataaattg ttttgataca agattgcagg
     2941 cagacgacta tttattgtcg tcccttcctc ctactgttac ccaggacgga aaaatcatca
     3001 ggccggaaag ggtgggcgat aaatggattt tgaacggaaa gccggtcacg ctgtcttatc
     3061 cgaaatgttc gaattacgaa caagttaaat ccggagctta tctcgggtct atggttttaa
     3121 ttctgtttgt cgttatttac ggcttcaggc tgctgattaa tttcttaaaa gacataggca
     3181 aagtaggggc gtgatgatgt ttgtcgattt ttggtttttg ctcggatttt tcctggcttt
     3241 gtctgtcgct ttgatattta tatgacgtgt tttaaaatca ggctttcaaa acaacctttg
     3301 aaagacagaa acatgaacaa gccgtttatc acgcaggcgc agttggcact ttataaatat
     3361 cagccgtcca gcaagtattt tgggcagtcg atggcattaa ttgcgtctaa ggaatttgaa
     3421 gagtttgtaa gaaatgtaaa agaatacgac gtaatagaat gtttctctta ttttttaaat
     3481 aagagggtaa cgcataatat ttggaaaatt tatttttctg atg
//
LOCUS       DAXIDM010000146         3490 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000146 DAXIDM010000000
VERSION     DAXIDM010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3490
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.146"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            156..3269
                     /locus_tag="ACFOAE_001924"
     CDS             156..3269
                     /locus_tag="ACFOAE_001924"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFC6885337.1"
                     /translation="MAVIIFVNGIRAVNGLVKSSINTANAFAEEGLDVHLINFVGNIT
                     GAEHLYPPFHLHPNVKTSSIIDLFNDIPENVSCRNTPFYSIHQQFFKAEYSAHYKHVL
                     MKIESLLSAEDSIIFTHPLQLEMYRLANNDIKSKAKLIVQIHGNYMEEIHNYEILARN
                     IDYVDYLQTVSDEMLEEMHSHFKIKKDKLVFIPNITYPISLEKKEADFFIKDNEDIDN
                     AQKFKRISIVGSIQPRKNQLDAIKIINKIKNENYILQIYGKSINKDYFELIKKYIKDN
                     KLQNRILFKGESSEQEIYENTDILIMTSESEGFPYIFMEGMVYDIPIVVYDFKYGAND
                     YSNYNENGCVFKTGDISGMAKKIIELLNNPEKYKELVQYNHNRFLKEYAKDVVMAKYF
                     TILPRSFNNVSLSSAFSRKELDEFQNITFSIEDSNDLAHIWNFELTNPAQNMNFFALV
                     GKRKFPMDAHIQGTQCTIKIAHKKTGNLLSLLLKKRNQLNLSRGYTLIAEDNSYEKYI
                     GAISNKGNFEIIANKKSSLVTINKSTLELHEIPHELHQNKLLIALPNMQTPLKITDDN
                     LIPIQASIKLEKIGNTYYPCFLPSGIFNNICLDYGEESKIINFSKYSYKYIYDSIRHI
                     EQHTDISDIIVCNVYSWELIRASVIESLMEFTGKWEKHFQTSPKIDYRFDHEGKRSMD
                     DVFSEETFIMEFPRKNGIDKKTAAFQNIPNSIVMEYPQTNGYSMRSHSLKSNVVAAKH
                     FLEKLNKIKVDIKFKKHDLANIKKMNRIIYEHLGININIQAFLKPRLEKFKREEKYFH
                     DFFKRNNFKEVIFPSTYWNPGIICAAHKQGIKVSDIQYAAITPYHPAYFKSPKSHYVA
                     DKLFLWSEYWNHELLPNPTREIGSGAAYWYALDDVRFSEKLNYDYIFLSQSRISSRLL
                     SFAIEFALKNPQLQLLFSKHPDENIDLKNRIIPDNLIISTESSIQGINESRVAVGVYS
                     TSLFEALACGKQTFVVKYPGYEIMSNEIDSGLFFAVETPEEMLEKTSPNWVAVADIEN
                     QFFGQEK"
BASE COUNT         1271 a          535 c          529 g         1155 t
ORIGIN      
        1 ttaataataa aatagattaa gctattctta aattcagaat attgcttatc tatattaaaa
       61 atttctaatt tttaaggttc tgattgaaat cagaacctta tttcaactat tactttttac
      121 tcataatcga attatatact ttaggacttt ataatatggc tgttattata tttgttaacg
      181 gaattcgggc tgtaaatggc cttgttaaat catctatcaa tactgcaaac gcttttgctg
      241 aagaaggact ggatgttcat ttaattaatt ttgttggcaa tattactgga gcagagcatt
      301 tatacccccc attccactta catcccaatg tcaaaacctc cagcatcata gatttattta
      361 atgacattcc agaaaatgtt agctgccgaa atactccttt ttattctatt catcaacaat
      421 tcttcaaagc tgaatatagt gcccactata agcatgtttt gatgaaaatt gaatctttat
      481 tatctgcaga agatagcatt atcttcactc atcctcttca actggaaatg tatcgtttag
      541 cgaataatga tatcaagtca aaagccaaac taattgtaca aattcatggt aattatatgg
      601 aagaaatcca taactatgaa attttggcac gaaatatcga ttatgttgac tatcttcaaa
      661 cggtatctga tgaaatgctg gaagaaatgc attcccattt caaaatcaaa aaagacaaat
      721 tagtttttat tccaaacatc acttatccca tttcattaga aaaaaaagaa gctgatttct
      781 ttattaagga taatgaagac atcgataatg ctcagaaatt taaacgtatc tctattgttg
      841 gcagcattca gccaagaaaa aaccaattgg atgccattaa aatcatcaat aaaattaaaa
      901 atgaaaatta cattttacag atatatggca aatctattaa taaagattac tttgaattaa
      961 ttaaaaaata tattaaagac aataagttac aaaaccgtat cttattcaaa ggtgaatctt
     1021 ccgagcagga aatttatgaa aatacagata tcctgatcat gacatcagaa agtgagggat
     1081 ttccatatat atttatggaa ggcatggtgt atgatattcc aatcgttgta tatgatttta
     1141 aatatggagc gaatgattac agtaactata atgaaaatgg ttgtgttttt aaaactggtg
     1201 atatttctgg aatggcaaaa aaaataattg agctattaaa taacccagaa aaatataaag
     1261 aattagttca atataatcac aatcgcttct taaaagaata tgcaaaagat gtggttatgg
     1321 ctaaatattt cactattctt ccgcgcagct ttaataacgt atcattatcg tctgctttca
     1381 gccgaaaaga attggacgaa ttccaaaata ttactttttc tattgaagat tctaatgatt
     1441 tagctcatat ttggaatttc gagctaacca atcctgcaca aaatatgaat ttttttgctt
     1501 tagttggcaa gcgaaaattt ccaatggatg ctcatatcca aggaacacag tgtacgatta
     1561 agatagctca taaaaagaca gggaatttat tgtcgctttt actaaaaaaa cgaaatcagt
     1621 tgaatttatc aaggggatat accttaattg cagaagataa tagctatgaa aaatatattg
     1681 gagcaatatc taataaaggt aactttgaaa ttattgcaaa taaaaagagc tcattagtta
     1741 ctataaacaa aagtacctta gagttgcatg agattcccca tgaactacat cagaataaat
     1801 tactgattgc tttacccaac atgcaaacgc ctctaaaaat tactgatgat aatttaatac
     1861 ctatccaagc ctccataaaa ttagaaaaga ttggaaatac ttattaccca tgtttcttgc
     1921 catctggcat atttaataat atctgcttag attacggtga agaatccaaa attattaatt
     1981 ttagtaaata ttcttataaa tatatctatg actcaattcg tcatattgag caacatacag
     2041 atatatcgga tattatcgtt tgcaatgttt attcttggga acttattcgt gcctcagtta
     2101 ttgagagcct tatggaattt accggaaaat gggaaaaaca ctttcagact tctcctaaaa
     2161 ttgattatcg atttgatcat gaaggtaagc gttcgatgga tgatgtcttt tcagaagaaa
     2221 catttattat ggaatttccg cgtaaaaatg gtatagataa gaaaacagca gccttccaaa
     2281 atataccaaa cagtattgta atggagtatc cgcagaccaa tggttacagt atgcgcagtc
     2341 attcactgaa aagtaatgta gttgcggcaa aacattttct tgaaaaatta aataaaatta
     2401 aggtagatat taaatttaaa aagcatgacc ttgcaaacat caaaaaaatg aatcgaatta
     2461 tttatgagca tttaggcatt aacataaata tccaagcatt tctaaaacca cgattagaaa
     2521 aatttaagcg tgaagaaaaa tattttcatg atttcttcaa aagaaataat tttaaagagg
     2581 taatttttcc aagcacttat tggaatccag gtattatttg tgctgcacat aaacaaggta
     2641 ttaaggtatc tgatattcaa tatgctgcca ttactcctta tcatcctgcg tattttaaat
     2701 caccaaaatc acattacgtt gctgataaat tgttcttatg gtctgaatat tggaatcatg
     2761 agcttttacc aaatccaaca cgagagattg gttctggtgc cgcatattgg tatgcattag
     2821 atgatgtgag attttcagaa aaactgaatt atgactatat ctttctatct caaagtagga
     2881 tttcttcgcg cttgcttagt tttgcaattg agtttgcatt aaaaaatcct caactacagc
     2941 ttttattttc taagcatcca gatgaaaata tagatttaaa gaacagaatt attcctgata
     3001 atcttataat ctccacggaa tcttctatac aaggcatcaa tgaatctcgc gttgctgtag
     3061 gtgtttattc aactagctta tttgaggcat tagcatgcgg caaacaaact tttgttgtta
     3121 aatatccggg atatgaaatt atgtcaaatg aaatagattc agggttattc tttgcagtag
     3181 aaacacctga agaaatgctt gagaaaacaa gcccgaattg ggtggctgtg gcagatattg
     3241 aaaaccagtt ttttggccaa gaaaaataat ttttaagtta atctttaaaa gtgcaatatt
     3301 tttcttattt taaatattgc actttattct tttaatcata ggaactcaca tgtattctga
     3361 acagggaatt aataatacta ttaacatatc tactacatct ttaaccaatg ccacgcaact
     3421 aactgtgatc gggaataata actctgtata tataggtaat aattgtaaaa tcgtcagctc
     3481 caatattaga
//
LOCUS       DAXIDM010000147         3432 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000147 DAXIDM010000000
VERSION     DAXIDM010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3432
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.147"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            43..711
                     /locus_tag="ACFOAE_001925"
     CDS             43..711
                     /locus_tag="ACFOAE_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015627 - type II protein secretion
                     system complex [Evidence IEA];
                     GO_process: GO:0015628 - protein secretion by the type II
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GspH/FimT family pseudopilin"
                     /protein_id="HFC6885338.1"
                     /translation="MCTRKQQGFTLTELLIVMAIAAIMAMIALPNMSQWIASRRIASH
                     AERVANLLRFSRGEAVRLNLPVYICPVQVKKDGAPNNKCDSGKKGQGMLAFGDKNGNK
                     IYDNDTADVLLRSVVLNDDINNKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYTK
                     DQHLTSKSSFFYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTV
                     CQYK"
     gene            741..1361
                     /gene="pilV"
                     /locus_tag="ACFOAE_001926"
     CDS             741..1361
                     /gene="pilV"
                     /locus_tag="ACFOAE_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus modification protein PilV"
                     /protein_id="HFC6885339.1"
                     /translation="MKNNDCFRLKNPQSGMALIEVLVAMLVLTIGILALLSVQLRTVA
                     SVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKNYNLYMGNHTLPHTLSAVDGDFA
                     IDAMKTKGQLAEAQLKRFSYELKNALPDAAAIHYTVCKDSSGNAPTLSGSTFSQNCDG
                     SANGDTLIKVLWVNDSAGDSDISRTNLEVSGDNIVYTYQARVGGRE"
     gene            1358..2323
                     /locus_tag="ACFOAE_001927"
     CDS             1358..2323
                     /locus_tag="ACFOAE_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilW family protein"
                     /protein_id="HFC6885340.1"
                     /translation="MRRKMLNVPKGSYDGMKGFTIIEFLVAGMLSMIVLMAVGSSYFT
                     SRKLNDAANERLAIQQDLRNAATLIVRDARMAGSFGCFNMSEHTEKNVVSDVAQKNRL
                     FSLKGSSANKLIPNGTDNKLIPITESLDIGYQGFTQRLNALVFQYGIDDLDASAETVV
                     VSSCSKIAKPGKKISTLQEAKSALQITNDDKQNGNITRQRYVVNAYAVGRIASEEGLF
                     RFQLDDKGKWGNPQLLVKKINKMDIRYIYVSDCPEDDDAGKEEKFKYTGTFDSSTNAV
                     TPAGVEVLLSSGTDTKIAASSDNHIYAYRIDATIRGGNVCANRTL"
     gene            2302..2901
                     /locus_tag="ACFOAE_001928"
     CDS             2302..2901
                     /locus_tag="ACFOAE_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002229321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilX N-terminal domain-containing pilus assembly
                     protein"
                     /protein_id="HFC6885341.1"
                     /translation="MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNT
                     EQRISANESDRKLALSLAEAALREGELQVLDLEYDTDSKVTFSENCGEGLCTAVNVRT
                     NTNNDNEEAFDNIVVQGKPTVEAVKRFCPANSTDLCIDKKGMKYKKGTRSVSKMPRYI
                     IEYLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE"
     gene            2906..3379
                     /locus_tag="ACFOAE_001929"
     CDS             2906..3379
                     /locus_tag="ACFOAE_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilX family type IV pilin"
                     /protein_id="HFC6885342.1"
                     /translation="MEQKGFTLIEVMIVVTILGIISVIAIPSYQSYIEKGYQSQLYTE
                     MVGINNISKQFILKNPLDDNQTIKSKLEIFVSGYKMNPKIAEKYNVSVHFVNKEKPRA
                     YSLVGVPKTGTGYTLSVWMNSVGDGYKCRDAASARAYSETLSADAGCEAFSNRKK"
BASE COUNT          988 a          671 c          863 g          910 t
ORIGIN      
        1 aatttaatcc acgatacatt accagttaac gttctattgc ctatgtgtac acgaaaacaa
       61 caaggtttca cgctaacaga gctgctcatc gtgatggcca ttgcagccat tatggcgatg
      121 atagccctcc ccaatatgag ccaatggatt gcatcccgcc gcattgccag tcacgcggag
      181 cgggttgcca accttttgcg tttctccagg ggcgaagccg tccggctcaa tctccctgtc
      241 tatatctgtc ctgttcaagt taaaaaagac ggtgcgccca acaataaatg tgactccggc
      301 aagaaggggc agggaatgtt ggcttttggc gataagaatg gcaataagat atatgacaat
      361 gatacggcgg atgttcttct ccgcagtgtg gtattgaatg atgatatcaa taataagcgg
      421 attaattatg ccttcaacca tatcgctttc ggtcagactc agccgaccgc tgaccgtgta
      481 gtttggacat tcaatcaaaa cgggacgttc ggttatacga aagaccagca tcttacaagc
      541 aaatccagct ttttttattc cgacggttat atccaaatcg tgctgacaga tgcgagagca
      601 gtttcagatg ccgataagaa attccgttcg gcggtggttt tgattaacag cagcggcagg
      661 gttgaggttt gtcctagaaa cgataggcgt accgtatgcc aatataaatg attgttttag
      721 tcggtttggg aaataaaaaa atgaagaata atgattgctt ccgcctgaaa aacccccagt
      781 ccggtatggc gctgatagaa gtcttggtcg ctatgctcgt tctgaccatc ggtattttgg
      841 cactattgtc tgttcagttg cggacagtcg cttccgtcag ggaggcagag acgcaaacca
      901 tcgtcagcca aatcacgcaa aacctgatgg aaggaatgtt gatgaatccg accattgatt
      961 cggacagcaa caagaaaaac tataatcttt acatgggaaa ccatacacta ccgcatacac
     1021 tatcagctgt ggatggcgat tttgcgattg atgccatgaa aactaagggg caattggcag
     1081 aggcacaatt gaagagattt agttatgagc tgaaaaatgc cttgccggat gcggcagcca
     1141 tccattacac cgtctgcaag gattcgtcgg gtaatgcgcc gacattgtcc ggcagtactt
     1201 tttctcaaaa ttgcgatggt agtgcaaatg gggatacttt gattaaagta ttgtgggtaa
     1261 atgattcggc aggggattcg gatatttccc gtacgaatct tgaggtgagc ggcgacaata
     1321 tcgtatatac ttatcaggca agggtcggag gtcgggaatg agacgtaaaa tgctaaacgt
     1381 accaaaaggc agttatgatg gtatgaaggg ttttaccatt attgaatttt tggttgcggg
     1441 catgctcagt atgattgtcc tgatggcggt cggatcgagt tacttcacgt cccggaaatt
     1501 aaatgatgcg gcaaacgagc gtcttgctat tcaacaggat ttgcggaatg cggcaacatt
     1561 gattgtccgc gatgcaagaa tggcggggag cttcggttgt ttcaatatgt ctgagcatac
     1621 cgaaaagaat gttgtttccg atgtggcgca aaaaaaccgt cttttttcct taaaagggag
     1681 cagtgcaaat aaacttatcc ccaacggtac agataataaa cttatcccca taacggaatc
     1741 tttagatatc ggatatcagg gttttaccca gcgccttaac gcattggttt tccaatacgg
     1801 tatcgatgat cttgatgcga gtgctgagac tgttgtagtc agcagctgtt ccaaaatagc
     1861 aaaaccgggt aagaaaatat ctaccttgca agaagcaaag agtgcattac agattactaa
     1921 tgatgataaa caaaatggaa atatcacccg tcaaaggtat gtggtcaatg cctatgcggt
     1981 cggcaggatt gccagtgagg aaggtttgtt ccgcttccaa ttggatgata agggcaagtg
     2041 gggtaatcct cagttgttgg ttaaaaagat taataaaatg gatatacggt atatttatgt
     2101 ttccgattgt cctgaagatg acgatgccgg caaagaggaa aaattcaaat atacgggtac
     2161 attcgacagc tccacaaatg ctgttacgcc cgccggggtg gaggttttat tgagtagcgg
     2221 tactgatacc aagattgccg cttcttcaga caatcatatt tatgcttacc gtatcgatgc
     2281 gacaatacgc gggggaaatg tatgcgcaaa cagaacactt tgacgggaat cccgacttct
     2341 gacggacaga gggggtttgc actgtttatc gtgctgatgg tgatgatcgt cgtggctttt
     2401 ttggttgtaa ctgccgcgca gtcttacaat accgagcagc ggatcagtgc caacgaatca
     2461 gacaggaaat tggctttgtc tttggccgag gcggctttgc gggaaggcga acttcaggtt
     2521 ttggatttgg aatatgatac ggacagtaag gttacattta gcgaaaactg tggagaaggt
     2581 ctgtgtaccg cagtgaatgt gcggacaaat acaaataatg ataatgaaga ggcttttgac
     2641 aatatcgtgg tgcaaggcaa gcccaccgtt gaggcggtga agcgtttttg ccctgcaaat
     2701 tctaccgacc tgtgcattga caagaaaggg atgaaatata agaaaggcac gagaagcgtc
     2761 agcaaaatgc cacgttatat tatcgaatat ttgggcgtga agaacggaga aaatgtttat
     2821 cgggttactg ccaaggcttg gggtaagaat gccaataccg tggtcgtcct tcaatcttat
     2881 gtaagcaata atgatgagta ataaaatgga acaaaaaggg tttacattga ttgaggtaat
     2941 gatagttgtc acgatactcg gcattatcag cgtcattgcc ataccttctt atcaaagtta
     3001 tattgaaaaa ggctatcagt cccagcttta tacggagatg gtcggtatca acaatatttc
     3061 caaacagttt attttgaaaa atcccctgga cgataatcag accatcaaga gcaaactgga
     3121 aatatttgtc tcaggctata agatgaatcc gaaaattgcc gaaaaatata atgtttcggt
     3181 gcattttgtc aataaggaaa aaccaagggc atacagcttg gtcggcgttc caaagacggg
     3241 gacgggttat actttgtcgg tatggatgaa cagcgtgggc gacggataca aatgccgtga
     3301 tgccgcttct gcccgagcct attcggagac tttgtccgcg gatgccggct gtgaagcttt
     3361 ctctaatcgt aaaaaatagg gctgttttgc caatgccgtc tgaaaatcaa tgttcagacg
     3421 gcatttttat gg
//
LOCUS       DAXIDM010000148         3417 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000148 DAXIDM010000000
VERSION     DAXIDM010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3417
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.148"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(424..1275)
                     /locus_tag="ACFOAE_001930"
     CDS             complement(424..1275)
                     /locus_tag="ACFOAE_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HFC6885343.1"
                     /translation="MTLLGIKLKQTQQLNQRLQQSLRVLQMSGIELEREVENWLSDNP
                     LLERKDTDEFSDAEFSHYTAPARQIGGDEGEDMLSNIAGEQDFKQYLHAQVCEHPLSD
                     QEAACVHILIDFLDEQGYLTDSIEDILDHTPLEWMLDEAMLKQALTALKKFDPAGVAA
                     ADLNESLILQIERLGECAAKPAALHIVRNALDSIDGNRSQTLARIKKRLPQTDSGTLE
                     AALDLIASLNPFPAAGFASSTPTPYSDEALANLLAFRGMEVSRRTIAKYRESFEIPAA
                     HKRKTAE"
     gene            1623..3137
                     /gene="katA"
                     /locus_tag="ACFOAE_001931"
     CDS             1623..3137
                     /gene="katA"
                     /locus_tag="ACFOAE_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase KatA"
                     /protein_id="HFC6885344.1"
                     /translation="MTTSKCPVTHLTMNNGAPVADNQNSLTAGPRGPLLAQDLWLNEK
                     LADFVREVIPERRMHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFTTVAG
                     ERGAADAERDIRGFALKFYTEEGNWDVVGNNTPVFFLRDPRKFPDLNKAVKRDPRTNM
                     RSATNNWDFWTLLPEALHQVTIVMSDRGIPAGYRHMHGFGSHTYSFWNEAGERFWVKF
                     HFRTQQGIKNLTNEEAAKIIADDRESHQRDLYEAIERGEFPKWTMYIQVMPEADAEKV
                     PYHPFDLTKVWPKKDYPLIEVGEFELNRNPENFFADVEQSAFAPSNLVPGVGASPDKM
                     LQARLFNYADAQRYRLGVNFRQIPVNRPRCPVHSNQRDGQGRADGNYGSLPHYEPNSF
                     GQWQQQPDFAEPPLKINGDAAHWDYRQDDDDYFSQPRALFNLMNDAQKQALFGNTAAA
                     MGDAPDFIKYRHIRNCYRCDPAYGEGVAKALGLTVEDAQAARATDPALGQAGLL"
     gene            3213..>3417
                     /locus_tag="ACFOAE_001932"
     CDS             3213..>3417
                     /locus_tag="ACFOAE_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885345.1"
                     /translation="MPSETSFDRFRRHFPIPPPPFQWAFFIKRKISRHSRPTAHFSAV
                     IPAPSPPVQTGTKTFPRHSRESGN"
BASE COUNT          825 a          962 c          868 g          762 t
ORIGIN      
        1 cgtcattccc gcgaaagcgg gaatccaggt tcgttgagtt tcggtcattt ccgataaatt
       61 cttgcaactt tgcgtttcta gattcccact ttcgtgggaa tgacggcgga gggttgctgt
      121 tttcccgaca aattcccgcc atctaaaatc tcgttatcca tacaagaacc gaaaatcttg
      181 ccattctcac aaaaacagaa attcaaaacc agaaatccca aaccctcggc attcccgcga
      241 aaacgggaat ccaggttcgt tgagtttcgg tcatttccga taaattcttg caactttgcg
      301 tttctagatt cccactttcg tgggaatgac gggatgcagg tttccgcgcg gacggattcg
      361 gcattcccgc tttcgcagaa atgccggctt ttggtttgtt gtctttataa gattattcgg
      421 caattattct gcggttttgc gtttgtgtgc tgccggaatc tcaaaggatt ctctgtattt
      481 ggcaatggtg cggcgagaaa cctccatgcc gcggaaagcc agcaggttgg cgagcgcctc
      541 gtcagaatac ggcgtgggtg tggacgaggc aaaaccagcg gcgggaaagg gattgagcga
      601 agcaatgagg tcgagtgcgg cttcgagtgt gccgctgtcg gtttggggca ggcgtttttt
      661 tattcgcgcg agggtttggc tgcggttgcc gtcaatgctg tcgagggcgt ttcggacgat
      721 atgcagggcg gcgggtttgg cagcacattc gcccaatctt tctatctgca gtatcagcga
      781 ttcgttcaaa tcggcggcgg ccacgcctgc cgggtcgaat tttttcaatg cggtcagggc
      841 ttgtttcagc attgcctcat ccaacatcca ctccaagggc gtatggtcga ggatgtcttc
      901 gatgctgtcg gtcagataac cttgctcgtc aaggaaatcg ataaggatgt ggacacaggc
      961 ggcttcttgg tcggaaagcg ggtgttcgca cacttgcgcg tgcaggtatt gcttgaaatc
     1021 ctgctcaccg gcgatgttgg acagcatatc ttcgccttcg tctccgccga tttggcgcgc
     1081 gggcgcagtg taatggctga actcggcatc ggaaaattca tccgtgtctt tgcgttcgag
     1141 cagggggttg tccgacagcc agttttcgac ctcgcgttca agttcgatac ccgacatctg
     1201 caatacgcgc aaagattgtt gcagccgctg gttgagctgc tgggtctgtt tgagctttat
     1261 tccgagtaag gtcatgataa tgtggggaaa attgttattt tcagcctgtc ggcgcaaaaa
     1321 atgccgcaaa gcgtcattgc attataaatg gttttaatga gcgggttcgg attccgttcg
     1381 ataacaaaaa acaaacgaaa atcaagaacc gattgcttat aataatatta aatcgatttc
     1441 atagttttaa tagcgaaaat cttggcgtat agtcgcatcc atagttttta caaaagggaa
     1501 ataaaatgtc gattcaagaa atttattgca atcaagaaac cggttacgaa tacgctttcc
     1561 gccaaatcgt actgtaagcc gtttaccccc atttgaccaa cctgagaaaa ggaacaagag
     1621 cgatgactac ctccaaatgc cctgtaaccc atctgaccat gaacaacggc gcgcctgttg
     1681 ccgacaatca aaacagcctg accgccggtc ctcgcggccc tctgctggcg caggatttgt
     1741 ggctgaatga aaaactcgcc gacttcgtgc gcgaagtcat ccccgaacgc cgtatgcacg
     1801 ccaaaggttc gggcgcgttc ggtacgttta ccgtaacgca cgacatcacc aaatacaccc
     1861 gcgccaaaat cttcagcgaa gtcggcaaaa aaaccgagat gttcgcccgt ttcaccaccg
     1921 tggcaggcga acgcggcgca gccgatgcag aacgcgacat ccgcggtttt gccttgaaat
     1981 tttataccga agaaggcaac tgggatgtgg tcggcaacaa cacgcccgtg ttcttcctgc
     2041 gcgacccgcg taagttcccc gacctgaaca aagccgtcaa acgcgacccg cgcaccaata
     2101 tgcgctctgc cacaaacaac tgggacttct ggacgctgct gcccgaagca ctgcaccaag
     2161 ttaccatcgt gatgagcgac cgcggcatcc ccgccggcta ccgccatatg cacggcttcg
     2221 gttcgcatac ctacagcttc tggaacgaag caggcgagcg tttttgggtg aaattccatt
     2281 tccgcaccca acaaggcatt aaaaacctga ccaacgaaga agccgccaaa atcatcgccg
     2341 acgaccgcga aagccatcag cgcgacttat acgaagccat cgaacgcggc gagtttccga
     2401 aatggacgat gtacatccaa gtcatgcctg aagcagacgc ggaaaaagta ccttatcatc
     2461 cgtttgactt gaccaaagtt tggccgaaaa aagactatcc gctgattgaa gtgggcgaat
     2521 tcgagttgaa ccgcaatccc gaaaacttct tcgccgatgt ggaacaatcc gccttcgcac
     2581 cgagcaacct tgtgcccggt gtcggcgcca gcccagataa aatgttgcaa gcccgtttgt
     2641 tcaattacgc cgacgcgcaa cgctaccgct tgggcgtgaa cttccgccaa atccctgtca
     2701 accgtccgcg ttgccctgtt cacagcaacc agcgcgacgg acaaggacgc gccgacggca
     2761 actacggcag cctgccgcac tacgaaccca acagcttcgg ccaatggcag cagcagcccg
     2821 acttcgccga accgcctttg aaaatcaacg gcgacgcggc gcactgggac taccgccaag
     2881 acgatgacga ctatttcagc caaccgcgcg ccctgttcaa cctgatgaac gacgcgcaga
     2941 aacaggcatt gttcggcaac accgccgccg caatgggcga cgcgcccgac ttcatcaaat
     3001 accgccatat ccgcaactgc taccgttgcg atccggcata cggcgaaggc gtggcaaaag
     3061 ccctcggact gactgtcgaa gacgcacaag ccgcccgcgc gaccgacccc gcactgggtc
     3121 aggccggttt gctgtaaggg ggcattatgt ggatggaaat tgaagaaatc ctgtcccgcg
     3181 ccgtccgcta ccggaaataa ccgggcataa aaatgccgtc tgaaacgtcg tttgaccgct
     3241 tcagacggca tttccccatc ccgcccccgc cgtttcagtg ggcgtttttt attaaacgca
     3301 aaatatcccg tcattcccgc cccacagccc acttttccgc cgtcattccc gcaccatccc
     3361 caccggttca aaccggcacg aaaacttttc cgcgtcattc ccgcgaaagc gggaatc
//
LOCUS       DAXIDM010000149         3414 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000149 DAXIDM010000000
VERSION     DAXIDM010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3414
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.149"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(214..1278)
                     /locus_tag="ACFOAE_001933"
     CDS             complement(214..1278)
                     /locus_tag="ACFOAE_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFC6885346.1"
                     /translation="MEKEFRILNIVSAKIWGGGEQYVYDVSKALGFRGCTMFTAVNKN
                     NELMHRRFSEVSSVFTTRLHTLNGLFSLCALTRFIRENRISHLMIHTGKIAALSILLK
                     KLTGVRLIFVKHNVVANKTDFYHRLIQKNTDRFICVSRLVYDVQTADNPFKEKYRIVH
                     NGIDTDRFPPSQEKPDSRFFTVAYAGRISPEKGLENLIEACVILHRKYPQIRLKLAGH
                     GHPDYMCRLKRNVSASGAEPFVSFEGFTEKLASFYRQSDVVVLPSLVPEAFGLSLCEA
                     LYCRTAVISNTLGAQKEIIEHHQSGILLDRLTPESLADEIERLVLNPEAKNALATAAH
                     QCVAARFTINHTADKLLDAI"
     gene            complement(1279..2037)
                     /locus_tag="ACFOAE_001934"
     CDS             complement(1279..2037)
                     /locus_tag="ACFOAE_001934"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC6885347.1"
                     /translation="MKKVSVLIVAKNEANHIRECIESCRFDKEVIVIDDHSTDNTAEI
                     AESLGAKVFRRHLNGDFGAQKTFAIEQAGGEWVFLIDADERCTPELSDEISKIVQTGD
                     YAAYFVERRNLFPNHPATHGAMRPDSVCRLMPKKDSSVQGKVHETVQTPYPKRRLKHF
                     MYHYTYDNWEQYFNKFNKYTSISAEKYREQGKPVRFVRDIILRPIWGFFKIYILNKGF
                     LDGKMGWIMSVNHSYYTMIKYVKLYYLYKSGGKF"
     gene            complement(2112..2187)
                     /locus_tag="ACFOAE_001935"
     tRNA            complement(2112..2187)
                     /locus_tag="ACFOAE_001935"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2152..2154),aa:Ile,seq:cat)
     gene            complement(2241..3414)
                     /locus_tag="ACFOAE_001936"
                     /pseudo
     CDS             complement(2241..3414)
                     /locus_tag="ACFOAE_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247614.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase"
BASE COUNT          772 a          833 c          910 g          899 t
ORIGIN      
        1 tctactatac attgtaacaa agcacttgat gcggcagcac aagccgggga agacgctgca
       61 aaactttgcc aataggctgc gtaatatcgg gggatattgg gattttctta ttttgaagga
      121 tggattcggg gtgtttcttt ccaatgaacg aatataattt ggcggtttgt tgcatcaaag
      181 gctttcagac ggcatatgcc gtctgaaagc ggcttatatt gcatccaata atttgtcggc
      241 ggtatggttg atggtaaaac gggcggcgac gcattgatga gctgccgttg ccagtgcgtt
      301 ttttgcttcg gggtttaaga cgaggcgttc gatttcgtcc gccaaagatt caggtgtcag
      361 cctatccagc agaatccccg attgatgatg ttcaataatt tccttttgcg cgcctaaagt
      421 attggaaatc accgccgttc ggcagtacag cgcctcgcat aatgacaaac cgaatgcctc
      481 cgggacgagg ctgggcaaaa ccacgacatc gctttggcgg taaaacgaag caagtttttc
      541 ggtaaaccct tcaaaagaaa caaatggttc tgctcccgaa gcagatacgt tccgcttcag
      601 gcggcacata taatccggat gtccgtgccc tgccaatttg agcctgattt gaggatattt
      661 ccgatgcagt atcacacagg cttcaatcag gttttccaat cctttttccg gactgatcct
      721 gccggcgtag gcgacggtaa aaaaacggct gtcgggtttt tcttgagagg gagggaaccg
      781 gtcggtatcg ataccgttat gaacaatccg gtatttttct ttaaagggat tgtcggcggt
      841 ttgcacatcg taaaccagac gggaaacgca aataaagcgg tctgtgtttt tctgtatcag
      901 gcggtggtaa aaatcggttt tgttggcgac gacattatgt ttgacaaata tcaggcgcac
      961 cccggtcagt tttttcaaaa gtatggataa ggcggcaatt ttgccggtgt gtatcatcag
     1021 gtgggaaatg cggttttccc ggataaagcg ggtaagcgcg cagagcgaaa acagcccgtt
     1081 gagcgtgtga aggcgtgtcg tgaaaacgga agaaacttcg gaaaatcgcc tgtgcatcaa
     1141 ttcattattt ttattgacgg cggtaaacat ggtgcagccc cgaaacccca atgcttttga
     1201 aacatcatag acatactgtt cgcccccacc ccaaatcttg gccgatacga tatttaatat
     1261 cctgaattct ttttccattt aaaattttcc gccagatttg tacagataat atagtttgac
     1321 atatttaatc atcgtgtaat agctgtggtt gacggacata atccaaccca tttttccatc
     1381 gagaaaccct ttgttcagga tataaatttt gaaaaaaccc caaatcgggc ggaggataat
     1441 gtccctaacg aaacgcacgg gctttccctg ctctcggtat ttctcggctg agatggaagt
     1501 gtatttgttg aatttgttga aatattgttc ccagttgtcg tatgtgtaat ggtacataaa
     1561 atgcttcaga cggcgtttgg ggtagggggt ttgtacggtt tcgtgtactt tgccttgcac
     1621 cgaactgtct tttttcggca tcagacggca tacgctgtcg ggacgcatcg ctccgtgtgt
     1681 ggcgggatgg ttggggaaaa ggttgcggcg ttcgacaaaa taggcggcat aatcgccggt
     1741 ttggacaatt tttgagattt catcagatag ttctggcgtg cagcgttcgt ctgcatcaat
     1801 cagaaaaacc cattctccgc ctgcctgttc gatggcaaat gttttttgcg ctccgaaatc
     1861 cccgttcaaa tgccgtctga agacttttgc acccaaactc tcggcaattt cggcagtatt
     1921 gtcggtgctg tggtcgtcaa taacgataac ttctttatcg aaacggcaac tttcaataca
     1981 ttcccgaatg tggtttgctt cgtttttggc aacaatcaat acgctgactt ttttcattat
     2041 caaggtttct caaagcattt tggtttcaca gggcggcaaa aaagcccaaa catacgtccg
     2101 ggcttgggaa ttggtgggtc cggtggggtt cgaacccacg accaagggat tatgagtccc
     2161 ctgctctaac ccctgagcta cagacccgtc aagagtaggc gcgtattgta tagcatagcg
     2221 gtgggattga caaacttatt tcatccgatg agtaaaacgc agttgcttcc cccaaaggca
     2281 aacgacgagc tggcggcaat gcgtttttcg gtttcccagc ggctgccgct gccggtcagg
     2341 ttgatggcgg gcaggttggg gtcgttctgc ccgtcccaaa gctggggcgg aagttttcct
     2401 tcgggattgc tttgccggtc ggcaatgccc cacgcgaacg cggcttcgat tgcgcccgcc
     2461 gcgcccagcg tgtgtccggt ttgcggcttg gtggacgtgc agggcgtatt gttgccgaaa
     2521 accgctgcaa cggcgcggct ttccatactg tcgttgtggt gcgtcccggt gccgtgcaga
     2581 ttaatccagc cgatgtcttc gggcgcaaga cctgcgtgtt gcaatgccgt ctgaaaggca
     2641 aggattgcgc cttacgcgtc ggggcggggc gtggaaatat ggtaggcatc gctgttggct
     2701 ccgtagccga cgagttcggc gtaaattatc gcaccgcgcc gtttggcgtg ttccaattct
     2761 tccagcacga aaatccccgc gccttcgccg atgaccagcc cgtcgcggtt cgcgtcgtat
     2821 gggcgcgggg ttttttccgg ttcgccgttg cggcggctgg cggcataaag cgagtcgaaa
     2881 acatacactt cggacgggaa aaattcttcg cctccgcccg ccagcatcat atcggtcaga
     2941 ccgtatttga tggcttcgta ggcataacct atgccttggc tgccggacga acacgcgctc
     3001 gatgtcggga tgatgcgtcc tttcagcccg aaaaagatgc cgatattggc ggcggcggtg
     3061 tgcggcatca tacgcacata ggtgttggca ctgaagttgc gcgacatgcc ggtcagcaac
     3121 aattcgccta catcgccgat gtctttggtg ctgccgctgg aagagccgca ggcaacgccc
     3181 atgcgtccgt cagtaatgct ttcgtctccg agcaaaccgg catccgtcaa agcctgctcc
     3241 gccgcatcga cgcacaaata cgacacacgc cccatacttc tgagctgctt gcgcgtccaa
     3301 tgtttcggcg gcgcgtaatc ctcaatcggc gcacccagtt gcgcttccaa ttcggggaaa
     3361 cgttcgtgcc aatccactat attttcgcaa gacgcgtttt gactgattcc aaaa
//
LOCUS       DAXIDM010000150         3362 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000150 DAXIDM010000000
VERSION     DAXIDM010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3362
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.150"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            27..1196
                     /locus_tag="ACFOAE_001937"
     CDS             27..1196
                     /locus_tag="ACFOAE_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6716 putative glycosyltransferase"
                     /protein_id="HFC6885348.1"
                     /translation="MNKKRVLLIASYDSFLNTGYAVAKEINYSTIDIYIHQTKKNILS
                     ESQLSLNGLSLKEINFFHIDDYFDKLMYQNYDIVILSLGNGLLTRFFRNSSKLNLTLP
                     IVITLFPGVIFGDSESIITRLGANILLFNNYYDYQIGNKFKERYNLSCTNILYGYPIL
                     RKKHHCSDGNKVYFIDQVKIPDGKKERLLILKKLIALANRYPHKDLVLLLRVHQNDIT
                     VHEDKYSYAELAKNMKLPDNFKIERKRTQDALQEMGYCLSFSSTMLFEAESCGIPIGV
                     ISDLGVDKKYANTHFKDSGVLVNLDTVDLDSPNTINPTWAELYTNPDSLSSKEFNQLL
                     EVTSTQPPSFDNYFIAVNDVQPVSMVLLRKFKKLIYHPKQFFVDSKLYKLIKFTK"
     gene            1244..2107
                     /gene="galU"
                     /locus_tag="ACFOAE_001938"
     CDS             1244..2107
                     /gene="galU"
                     /locus_tag="ACFOAE_001938"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFC6885349.1"
                     /translation="MQKIRKAVFPVAGMGARFLPATKASAKEMLPIVDKPLIQYAAEE
                     AVAAGCTELIFITGRNKRNIEDHFDKAYELETELEMREKHKLLGYVQKILPDHVSCIF
                     IRQAEALGLGHAVLCARPAVGNEPFAVILADDLIDAPQGALKQMVDIYNQSGNSILGV
                     ETVDPSQTGSYGIVEVEQLKSYQRVTNIVEKPKPEDAPSNLAVVGRYILTPRIFDLLT
                     NLPRGAGGEIQITDGIARLLDHEFVLAHAFEGKRYDCGSKLGYLEATVAYGLKHPELK
                     DDFKELLKQFV"
     gene            2190..3206
                     /gene="galE"
                     /locus_tag="ACFOAE_001939"
     CDS             2190..3206
                     /gene="galE"
                     /locus_tag="ACFOAE_001939"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFC6885350.1"
                     /translation="MNILVTGGTGFIGSHTVVSLLKSGHQVVILDNLCNSSINILPRL
                     KTITGQEIPFYQGDIRDREILRRIFAENRIDSVIHFAGLKAVGESVAEPIKYYDNNVS
                     GSLVLAEEMARAGVFSIVFSSSATVYGDPGKVPYTEDMPPGDTTSPYGASKSMVERIL
                     TDIQKADPRWSMILLRYFNPIGAHESGLIGEQPNGIPNNLLPYICQVAAGKLPQLAVF
                     GDDYPTPDGTGMRDYIHVMDLAEGHVAAMQAKSNVAGTHLLNLGSGRASSVLEIIRAF
                     EAASGLTIPFEIKPRRAGDLACFYADPSYTKAQIGWQTQRDLTQMMEDSWRWVSNNPN
                     GYDD"
BASE COUNT         1001 a          627 c          713 g         1021 t
ORIGIN      
        1 acttaatatc taatatttaa aatacaatga ataaaaaacg agtcctatta attgctagtt
       61 atgattcttt tttgaatact ggatatgctg ttgcaaaaga aattaactat tcaacaatcg
      121 atatttatat ccaccaaaca aaaaaaaata ttctttcgga atcacaatta agtttaaatg
      181 ggctttcttt aaaagaaatc aatttttttc atattgatga ttatttcgac aaattaatgt
      241 accagaatta tgatattgtt attctatcat taggtaatgg tttactgacg cgtttttttc
      301 ggaatagtag caaacttaat ttaacattac ctatagtaat tactctattt ccaggggtaa
      361 tttttggtga ttcagaaagt attataacta ggttaggtgc taatatttta ttgttcaata
      421 attattatga ttaccaaata ggcaataagt tcaaagaacg ttacaactta tcgtgtacaa
      481 atattttata tggttatcct atcctacgaa aaaaacacca ttgctctgat ggcaataaag
      541 tttatttcat tgatcaagta aaaattccag atggaaaaaa agaaagatta ttaattctaa
      601 aaaaattaat agcactggct aatcgctatc cacataaaga tttagtacta ttattacgtg
      661 tccatcaaaa tgatatcaca gtacatgaag ataaatactc ttatgctgaa ttagcaaaaa
      721 atatgaaatt gcctgataat tttaaaatag agagaaaacg gacacaagat gccttacaag
      781 aaatgggata ttgtttatca ttctcttcaa caatgttatt tgaagctgaa agctgcggaa
      841 ttcctattgg tgtcattagt gatttagggg ttgacaagaa atatgccaat acacatttca
      901 aagatagtgg tgttttggtt aatttagata cggtagactt ggactctcca aataccatta
      961 atccaacttg ggctgaacta tatactaatc cagatagcct ctcttcaaaa gagtttaacc
     1021 aattattaga ggttacttct actcaaccac ctagttttga taattatttt attgcagtta
     1081 atgacgttca gcctgtatct atggttctgt tacgtaaatt taaaaagctt atatatcatc
     1141 ctaagcaatt ctttgttgat tcaaaactat ataaattaat taaatttact aaataatttt
     1201 tactatgggt tgccttattt atttcaaagg agtgacataa aaaatgcaaa aaattcgtaa
     1261 agctgtattc cctgtagctg gcatgggagc ccgattctta cctgccacga aagccagcgc
     1321 taaagaaatg ctgccaatcg tggacaaacc gttaattcaa tatgctgcgg aagaagccgt
     1381 tgccgcgggt tgtactgaat tgatttttat caccggccgt aataagcgta atattgaaga
     1441 ccacttcgat aaagcctatg agttggaaac tgaactggaa atgcgtgaaa agcataaatt
     1501 gcttggctat gtgcaaaaaa ttctgcctga tcatgtcagc tgtattttca ttcgtcaggc
     1561 agaagctttg ggcttgggtc atgcggtatt atgcgcccgt cctgctgtcg gtaatgagcc
     1621 ttttgccgtg attttggccg atgacttgat tgatgcacca caaggcgcac tcaagcagat
     1681 ggtagatatt tacaatcaaa gcggcaacag cattttaggg gtagaaacag tcgatccttc
     1741 gcaaaccggt tcatacggca ttgtcgaagt ggaacagctg aaaagctatc agcgtgtaac
     1801 caatattgtg gaaaaaccaa agcctgaaga tgcgccgtca aatttagcgg tagtcggccg
     1861 ttatattttg acaccgcgta tttttgattt gctgactaat ctacctcgtg gtgcaggtgg
     1921 tgaaatccag ataactgatg gtattgcccg cctacttgac catgaatttg tcttggcgca
     1981 tgcgtttgaa ggtaagcgtt atgattgtgg cagtaagttg ggctatctgg aagccacggt
     2041 agcttatggc ttgaagcatc ccgaattaaa agatgatttc aaagaattat tgaagcaatt
     2101 tgtataattt taaggccgtc tgaaaaagaa aaggcatcat gttttttaca ctttcaggcg
     2161 gccttttaaa cataaagaag gaaaacgtga tgaacattct cgttaccggc ggcaccggtt
     2221 ttatcggctc gcacaccgtt gtttctttgc tgaaaagcgg tcatcaagtc gtgattttgg
     2281 ataacctatg caattccagc atcaatatcc tgccacgctt gaaaacgatt accggccaag
     2341 agattccgtt ttatcaaggc gatatccgcg atcgtgagat tttgcgccgt atttttgcgg
     2401 aaaaccgcat tgattcggtg attcattttg ccggcttgaa agcggtgggt gaaagtgtgg
     2461 ccgagccgat aaaatattat gataataatg tttccggcag cttggtgttg gcggaagaaa
     2521 tggcgcgtgc gggcgtgttt agcattgtgt tcagttcttc ggcgacggtt tatggcgatc
     2581 cgggcaaagt gccttatacc gaggatatgc caccgggcga caccaccagc ccttacggcg
     2641 catcgaaatc gatggttgag cgcattctca ctgacattca aaaagccgat ccgcgctgga
     2701 gcatgatttt gttgcgttat ttcaatccga ttggcgcgca tgaaagcggt ttgattggcg
     2761 agcagccaaa cggtatccca aataatttgt tgccttatat ctgccaagtg gcggcaggca
     2821 aactgccgca attagcggta ttcggtgatg actaccctac ccctgatggc acgggtatgc
     2881 gcgactatat tcatgtgatg gatttggcag aaggccatgt cgcggctatg caggcgaaaa
     2941 gcaatgtagc aggcacgcat ttgttgaact taggttccgg ccgcgcttct tcggtattgg
     3001 aaatcatccg cgcatttgaa gcggcttcgg gtttaaccat tccatttgaa atcaaaccgc
     3061 gccgcgccgg tgatttggcg tgcttctatg ccgacccttc ttatacgaag gcgcaaatcg
     3121 gctggcaaac gcagcgtgat ttaacccaaa tgatggaaga ttcatggcgc tgggtaagta
     3181 ataatccgaa tggctacgac gattaagttg acctgataca ggccgtctga aagagatgtt
     3241 ttcagacggc ctctttatct gaaaaacaca cattctgtct gctataatct gtttatattt
     3301 tttggctatc ctctgaaatt tatgagaaaa atcctcgtta ccggcggtgc gggctttatc
     3361 gg
//
LOCUS       DAXIDM010000151         3353 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000151 DAXIDM010000000
VERSION     DAXIDM010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3353
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.151"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..621)
                     /locus_tag="ACFOAE_001940"
     CDS             complement(<1..621)
                     /locus_tag="ACFOAE_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFC6885351.1"
                     /translation="MDRHFGRRRFLTVAAVAAAGAAVSFLPNPFAADGEKRNGDEKRN
                     ENVFFWKGVALGSGAELRLFGVDNRQAADLVNKVLAEVARLEKMFSLYREDSLISRLN
                     RDGYLTSPSADFLELLSLCRDIHALTDGAFDPTVQALWKLYADYFAARPDAETPPPQN
                     SVKEALKRVGFGKVSFDDREIRFAEKGMGLSLNGIAQGYSGLTKTST"
     gene            complement(632..1426)
                     /locus_tag="ACFOAE_001941"
     CDS             complement(632..1426)
                     /locus_tag="ACFOAE_001941"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFC6885352.1"
                     /translation="MKAYLDLMRHVLDNGTDKSDRTGTGTRSVFGYQMRFDLGKGFPL
                     LTTKKLHLRSIIHELLWFLKGDTNIKYLKDNNVSIWDEWADENGDLGPVYGYQWRSWP
                     APDGRHIDQIANVVEQIKKNPDSRRLIVSAWNPALVDEMALPPCHALFQFYVADGKLS
                     CQLYQRSADIFLGVPFNIASYALLTMMMAQVCGLEAGEFIHTFGDAHLYRNHFEQAEL
                     QLEREPRTLPVMKINPEVKDLFSFKFEDFELEGYDPHPHIKAAVSV"
     gene            1810..3144
                     /gene="gdhA"
                     /locus_tag="ACFOAE_001942"
     CDS             1810..3144
                     /gene="gdhA"
                     /locus_tag="ACFOAE_001942"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFC6885353.1"
                     /translation="MTDLNTLFANLKQRNPNQEPFHQAVEEVFMSLDPFLAKNPKYTQ
                     QSLLERIVEPERVVMFRVTWQDDKGQVQVNRGYRVQMSSAIGPYKGGLRFHPTVDLGV
                     LKFLAFEQVFKNALTTLPMGGGKGGSDFDPKGKSDAEVMRFCQAFMTELYRHIGADTD
                     VPAGDIGVGGREIGYLFGQYKKIRNEFSSVLTGKGLEWGGSLIRPEATGYGCVYFAQA
                     MLQTRNDSFEGKRVLISGSGNVAQYAAEKAIQLGAKVLTVSDSNGFVLFPDSGMTEAQ
                     LAALIELKEVRRERVATYAKEQGLQYFENQKPWGVAAEIALPCATQNELDEEAAKTLL
                     ANGCYVVAEGANMPSTLGAVEQFIKAGILYAPGKASNAGGVATSGLEMSQNAIRLSWT
                     REEVDQRLFGIMQSIHESCLKYGKVGDTVNYVNGANIAGFVKVADAMLAQGF"
BASE COUNT          877 a          929 c          804 g          743 t
ORIGIN      
        1 cgtactggtt tttgttaatc cactatagcc ttgcgcgatg ccgttcaagg acaaacccat
       61 acccttttcg gcaaaacgga tttcacggtc gtcaaacgag actttgccga agccgacccg
      121 tttcagggct tccttcacgc tgttttgagg aggcggcgtt tccgcatcgg gacgggcggc
      181 aaaataatcg gcatacagtt tccacaacgc ctgcactgtc ggatcgaacg cgccgtccgt
      241 cagcgcgtga atatcgcggc acaggctcaa cagttccaaa aaatccgccg acggcgaagt
      301 cagataaccg tccctgttca ggcggctgat caggctgtct tcacggtaaa ggctgaacat
      361 tttttccaaa cgcgccactt ccgccaaaac cttgttgacc aaatccgccg cctgtctgtt
      421 atccacgccg aacaggcgca gctccgcgcc ggaacccagc gcgacacctt tccagaaaaa
      481 cacattttca ttgcgttttt catccccgtt tcgtttttca ccgtcggcgg caaaaggatt
      541 cggcaggaaa gaaaccgccg cgcccgccgc cgcaacggcg gcaaccgtca gaaaacgcct
      601 gcgcccgaaa tgcctgtcca tatacccctc ctcagaccga cactgccgcc ttgatgtgcg
      661 gatgggggtc gtagccttcc aactcgaaat cttcaaactt gaaggaaaac aaatctttga
      721 cttcaggatt gattttcatc acaggcaagg tgcgcggttc gcgttccaat tgcaactctg
      781 cctgctcgaa atggttgcgg tacaaatgcg cgtcgccaaa cgtatggata aactcaccgg
      841 cttccaatcc gcacacttgc gccatcatca tggtcaacaa tgcgtagctg gcgatgttga
      901 acggtacgcc aaggaaaata tcggcgctgc gttggtaaag ctggcaggac agtttgccgt
      961 cggcaacgta aaactgaaac agcgcgtggc agggcggcaa tgccatttca tcgaccaaag
     1021 ccggattcca cgccgacaca atcaggcggc gcgaatcggg atttttcttg atttgttcca
     1081 ccacattggc gatttgatcg atatgcctgc cgtcgggtgc gggccagctg cgccattggt
     1141 agccgtacac cgggcccaaa tcgccgtttt cgtccgccca ctcgtcccaa atggaaacat
     1201 tgttgtcctt taggtatttg atattggtat cgcctttgag aaaccaaagc agctcgtgga
     1261 taatcgagcg caaatgcagc tttttggtcg tcagcagcgg aaaacctttg cccaagtcaa
     1321 aacgcatctg ataaccgaat acggagcgcg tgcccgtacc ggtgcggtct gatttgtccg
     1381 taccgttgtc gaggacgtgg cgcatcaagt ccaaataggc tttcatagca gtctttcatc
     1441 aaattaaacg gcgcatattg taacatttcc ggataatgcc caaaacacgg atacaggcag
     1501 gcaggattgt tggcaatttc agtccttttc cacagtaaaa cccagtggga aaacaaaatt
     1561 accttgattg gaatcaaaaa atctagttta attacttaga ataaaatttc aataatattt
     1621 ttatttacga aattaattta tgattattga ttaattatcg gcaacaaaca tcaaacatcg
     1681 aaaacatgga aaaaataatg tcaacaattt ttgccaaatc gggcttggca tcagaaaaaa
     1741 ataggtttat attcccacct acaaatttgt tttcccatta gtacactatc aaccaaaagg
     1801 agtatccgaa tgactgacct gaacaccctt tttgccaacc tcaaacaacg caatcccaat
     1861 caggagccgt tccatcaggc ggttgaagaa gtcttcatga gtctcgatcc gtttttggca
     1921 aaaaatccga aatacaccca gcaaagcctg ctggaacgca tcgtcgaacc cgaacgcgtc
     1981 gtcatgttcc gcgtaacctg gcaggacgat aaagggcaag tccaagtcaa ccggggctac
     2041 cgcgtgcaaa tgagttccgc catcggtcct tacaaaggcg gcctgcgctt ccatccgacc
     2101 gtcgatttgg gcgtattgaa attcctcgct tttgaacaag tgttcaaaaa cgccttgacc
     2161 accctgccta tgggcggcgg caaaggcggt tccgacttcg accccaaagg caaatccgat
     2221 gccgaagtaa tgcgcttctg ccaagccttt atgaccgaac tctaccgcca catcggcgcg
     2281 gacaccgatg ttccggccgg cgacatcggc gtaggcgggc gcgaaatcgg ctacctgttc
     2341 ggacaataca aaaaaatccg caacgagttt tcttccgtcc tgaccggcaa aggtttggaa
     2401 tggggcggca gcctcatccg tcccgaagcg accggctacg gctgcgtcta tttcgcccaa
     2461 gcgatgctgc aaacccgcaa cgatagtttt gaaggcaaac gcgtcctgat ttccggttcc
     2521 ggcaacgtgg cgcaatacgc cgccgaaaaa gccatccaac tgggcgcgaa agtgctgacc
     2581 gtttccgact ccaacggctt cgtcctcttc cccgacagcg gtatgaccga agcgcaactc
     2641 gccgccttga tcgaattgaa agaagtccgc cgcgaacgcg ttgccaccta cgccaaagag
     2701 caaggtctgc aatactttga aaaccaaaaa ccgtggggcg tcgccgccga aatcgccctg
     2761 ccctgcgcga cccagaacga attggacgaa gaagccgcca aaaccctgtt ggcaaacggc
     2821 tgctacgtcg ttgccgaagg tgcgaatatg ccgtcgactt tgggcgcggt cgagcaattt
     2881 atcaaagccg gcatcctcta cgccccggga aaagcctcca atgccggcgg cgtagcaact
     2941 tcaggtttgg aaatgagcca aaacgccatc cgcctgtctt ggactcgtga agaagtcgac
     3001 caacgcctgt tcggcatcat gcaaagcatc cacgaatcct gtctgaaata cggcaaagtc
     3061 ggcgacacag taaactacgt caatggtgcg aacattgccg gtttcgtcaa agttgccgat
     3121 gcgatgctgg cgcaaggctt ctaagcaaac gccgccgctc cgcaaacaaa atgccgtccg
     3181 aaccgcaaat gctgttcaga cggcatttca ttatccgccc gttcgaatcg ggtgatacta
     3241 tttgtatcca gaattgttgg atagtttggg agtggagagg aagaaatgat tatggaccaa
     3301 tactatatgg agttaaagaa taagttatct aacagaccaa tcctactgga taa
//
LOCUS       DAXIDM010000152         3317 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000152 DAXIDM010000000
VERSION     DAXIDM010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3317
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.152"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(1..644)
                     /locus_tag="ACFOAE_001943"
                     /pseudo
     CDS             complement(1..644)
                     /locus_tag="ACFOAE_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611451.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            1251..2060
                     /locus_tag="ACFOAE_001944"
     CDS             1251..2060
                     /locus_tag="ACFOAE_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002230241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RTX iron-regulated FrpC family protein"
                     /protein_id="HFC6885354.1"
                     /translation="MRPYATTIYQLFILFIGSVFTMTSCEPVNEKTDQKAVSAQQAKE
                     QTSFNNPEPMTGFEHTVTFDFQGTKMVIPYGYLARYTQDNATKWLSDTPGQDAYSINL
                     IEISVYYKKTDQGWVLEPYNQQNKAHFIQFLRDGLDSVDDIVIRKDACSLSTTMGERL
                     LTYGVKKMPSAYPEYEAYEDKRHIPENPYFHEFYYIKKGENPAIITHRNYHRYGENDY
                     STSVGSCINGFTVRYYPFIREKQQLTQQELVGYHQQVEQLVQSFVNNPSKK"
     gene            2077..>3317
                     /locus_tag="ACFOAE_001945"
     CDS             2077..>3317
                     /locus_tag="ACFOAE_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885355.1"
                     /translation="MNEGEVVLTPEQIQTLRGYAFRGDTYGGWRYLANLGDRYADDAA
                     AIVGKDANLNGLNLWMKKGVENLWDDTVGKKTRLEKFDRVALQHFSQYVDLINENNGR
                     LPNTSEIERSYYKAVTENGVSSSAAIDLVINRSLPDMADGYWALGLGIEAERIHNEQA
                     VNNPNGSESDNRKQLISALDKGFDGSFKEKPFTFLQSVIMDVTKLGVEYTIDGWQKIG
                     GWGNGIINDLYKSVAKREWTGIFEIVNNNIKQFRDLFPNPEGWIDDGHQCFAPWVKET
                     KKRNGKYHVYDPLALDLDGDGIETVATKGFSGSLFDHNRDGIRTATGWVSADDGLLVR
                     DLNGNGIIDNGAELFGDNTKLADGSFAKHGYAALAELDSNGDNIINAADAAFQTLRVW
                     QDLNQDGISQANELRTLEELG"
BASE COUNT         1020 a          630 c          730 g          937 t
ORIGIN      
        1 caccaatccc gcaagatttt tagctgtcgg gacggtgtgc cgaagttaaa tcgaaattcg
       61 cattctttca agaacagcgg gaaagatttg cgatcaattc cgttctattt gcgcaagacg
      121 cgttttgcct gattccaaaa gttctcaatg ccgtttatgt ggttctgacg gtcagcaaat
      181 tccttggaat ggttgatgcg gtaatggata aaaccgctta cgtccaactt gtcgtaactg
      241 ctcaggctgt cggtataaac aatgctgtcc ggcatgattt tctgtttgat aacaggcatt
      301 aaagtatcgg acttggcatt atctacgaca acggtataga cccgtccgtt acgtttcaga
      361 atgccgaaga caaccacttt tcctgccgca ccgcgaccac gtctgccttt acgccgtccg
      421 ccgaaatcgc tttcgtcctg ctcgacaggg ccctcaaaaa cctcatcggc agccaaggcc
      481 aaatgatggt tgataaccgt gcggatttta cggtagaaca gtactgccga attgggatgg
      541 atacccaaaa tatcggcggc agaacgggcg gtaacttcca gcacaaaaaa acggagcagt
      601 tctttctgta cttttttctt taatttgcag tgcgttatct tcatatttcg agggtaacat
      661 atctgctaat gtagtacagc cccaaaaata taccaaaaac agcaaaacaa attgtaagga
      721 taggtatagg ctttgtaaag gtaaattgtg aaaaaagcag ttttttaaac gaatgaaacg
      781 gcttcgggct gaaatatatg ctgatgccct gttcttcccg tatttctcgt gtgttgtcaa
      841 agtgcaggct gctttgaaat cggtattgcc atctatgaac caccactttg ctttatttca
      901 gcgggcttga gatgtgtata agaatattgt tttgaataaa tttaaagaaa atgataatcg
      961 ttattgacga tttttaaagg aaagcgtaga gtgccaattc tatgaagcaa tacggtaagt
     1021 aacaatgaaa atatctactg cttgggtata gagcatattt cacaacccgt aactattctt
     1081 gcggaaacag agaaaaaagt ttctcttcta tcttggataa atatatttac cctcagttta
     1141 gttaagtatt ggaatttata cctaagtagt aaaagttagt aaattatttt taactaaaga
     1201 gttagtatct accataatat attctttaac taatttctag gcttgaaatt atgagaccat
     1261 atgctactac catttatcaa ctttttattt tgtttattgg gagtgttttt actatgacct
     1321 catgtgaacc tgtgaatgaa aagacagatc aaaaagcagt aagtgcgcaa caggctaaag
     1381 aacaaaccag tttcaacaat cccgagccaa tgacaggatt tgaacatacg gttacatttg
     1441 attttcaggg taccaaaatg gttatccctt atggctatct tgcacggtat acgcaagaca
     1501 atgccacaaa atggctttcc gacacgcccg ggcaggatgc ttactccatt aatttgatag
     1561 agattagcgt ctattacaaa aaaaccgacc aaggctgggt tcttgagcca tacaaccagc
     1621 aaaacaaagc acactttatc caatttctac gcgacggttt ggatagcgtg gacgatattg
     1681 ttatccgaaa agatgcgtgt agtttaagca cgactatggg agaaagattg cttacttacg
     1741 gggttaaaaa aatgccatct gcctatcctg aatatgaagc ttatgaagat aaaagacata
     1801 ttcctgaaaa tccatatttt catgaatttt actatattaa aaaaggagaa aatccggcga
     1861 ttattactca tcggaactat cataggtatg gagagaacga ttacagcact agcgtaggtt
     1921 cctgtattaa cggtttcacg gtacggtatt acccgtttat tcgggaaaag cagcagctca
     1981 cacagcagga gttggtaggt tatcaccaac aagtagagca attggtacag agttttgtaa
     2041 acaatccaag taaaaaataa tttaaaggat cttattatga atgagggtga agttgtttta
     2101 acaccagaac aaatccaaac cttgcgtggt tatgctttcc gtggcgatac ctatggcggt
     2161 tggcgttatt tggctaattt gggtgaccgt tatgcggatg atgctgctgc aattgtcggt
     2221 aaggatgcaa acttaaatgg tttgaattta tggatgaaaa aaggtgtgga aaacctatgg
     2281 gatgatacgg tcggtaaaaa gacccgttta gagaaatttg atcgggttgc attgcaacat
     2341 ttcagccaat atgtagatct aattaatgaa aataatggta gattacctaa cactagtgaa
     2401 attgagagaa gttactataa agccgttacc gaaaatggtg tttcttctag tgcagctatt
     2461 gatttagtta ttaatcgctc acttccggat atggcggatg gttattgggc attaggtttg
     2521 gggatagaag ccgaacgtat ccacaatgag caagcagtaa ataatccgaa cggtagcgaa
     2581 tcggataata gaaagcagtt aatatctgct ttagataaag gatttgatgg atcttttaaa
     2641 gagaagcctt ttactttttt acaatctgtg ataatggatg taacaaagtt aggtgttgaa
     2701 tatacaatag atggttggca aaaaattgga ggttggggta atgggataat caatgattta
     2761 tataaaagtg ttgcaaaaag agagtggact ggaatatttg agatcgttaa taataacatc
     2821 aagcaattta gagatctgtt cccaaatccg gaaggctgga tcgatgatgg tcaccaatgt
     2881 ttcgctcctt gggttaaaga aactaaaaaa cgcaatggca aatatcatgt ctacgacccc
     2941 cttgccctag atttggacgg cgacggcata gaaaccgttg ccaccaaagg cttttcaggc
     3001 agcctatttg accacaaccg cgatggcatc cgcaccgcca ccggttgggt ttctgccgat
     3061 gacggtctgc ttgtgcgcga tttgaacggc aacggcatca tcgacaacgg tgcggaactc
     3121 ttcggcgaca acaccaaact ggcagacggc tcttttgcca aacacggcta cgcggctttg
     3181 gccgaattgg attcaaacgg cgacaacatc atcaacgcgg cagacgccgc attccaaacc
     3241 ctgcgtgtat ggcaggatct caatcaggac ggcatttccc aagctaatga attgcgtacc
     3301 cttgaagaat tgggtat
//
LOCUS       DAXIDM010000153         3186 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000153 DAXIDM010000000
VERSION     DAXIDM010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3186
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.153"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            110..2878
                     /gene="tdfH"
                     /locus_tag="ACFOAE_001946"
     CDS             110..2878
                     /gene="tdfH"
                     /locus_tag="ACFOAE_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent zinc piracy receptor TdfH"
                     /protein_id="HFC6885356.1"
                     /translation="MRSSFRLKPICFYLMGVMLYHHSYAEDAGRAGSEAQIQVLEDVH
                     VKAKRVPKDKKVFTDARAVSTRQDIFKSSENLDNIVRSIPGAFTQQDKSSGIVSLNIR
                     GDSGFGRVNTMVDGITQTFYSTSTDAGRAGGSSQFGASVDSNFIAGLDVVKGSFSGSA
                     GINSLAGSANLRTLGVDDVVQGNNTYGLLLKGLTGTNSTKGNAMAAIGARKWLESGAS
                     VGVLYGHSRRSVAQNYRVGGGGQHIGNFGAEYLERRKQRYFVQEGGLKFNSNSGKWER
                     DFQKSYWKTKWYQKYDDPQELQKYIEGHDKSWRENLAPQYDITPIDPSSLKQQSAGNL
                     FKLEYDGVFNKYTAQFRDLNTKIGSRKIINRNYQFNYGLSLNPYTNLNLTAAYNSGRQ
                     KYPKGSKFTGWGLLKDFETYNNAKILDLNNTATFRLPRETELQTTLGFNYFHNEYGKN
                     RFPEELGLFFDGPDQDNGLYSYLGRFKGDKGLLPQKSTIVQPAGSQYFNTFYFDAALK
                     KDIYRLNYSTNTVGYRFGGEYTGYYSSEGEFKRAFGENSPTYKKHCNPSCGLYEPVLK
                     KYGKKRANNHSVSISADFGDYFMPFASYSRTHRMPNIQEMYFSQIGDSGVHTALKPER
                     ANTWQFGFNTYKKGLLKQDDTLGLKLVGYRSRIDNYIHNVYGKWWDLNGDIPSWVSST
                     GLAYTIQHRNFKDKVHKHGFELELNYDYGRFFTNLSYAYQKSTQPTNFSDASESPNNA
                     SKEDQLKQGYGLSRVSALPRDYGRLEVGTRWLGNKLTLGGAMRYFGKSIRATAEERYI
                     DGTNGGNTSNVRQLGKRSIKQTETLARQPLIFDFYAAYEPKKNLIFRAEVKNLFDRRY
                     IDPLDAGNDAATQRYYSSFDPKDKDEDVTCNADKTLCNGKYGGTSKSVLTNFARGRTF
                     LMTMSYKF"
     gene            2908..3147
                     /locus_tag="ACFOAE_001947"
     CDS             2908..3147
                     /locus_tag="ACFOAE_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885357.1"
                     /translation="MPSESPSDGICFPKRIILPQAYANPFYRIGNSKKNPFHSHAGKP
                     VDFGYFWLFRVIYESSFPQKRESRHSMLRQFIEND"
BASE COUNT          901 a          792 c          773 g          720 t
ORIGIN      
        1 attgaaatct tcagacggta tatcgaattt acacttttta atgtttatgc cgcctaaaaa
       61 aatgctaata tatttcttaa ttgtctgact gtttattgtt gaggaaaata tgagatcttc
      121 tttccggttg aagccgattt gtttttatct tatgggtgtt atgctatatc atcatagtta
      181 tgccgaagat gcagggcgcg cgggcagcga ggcgcagata caggttttgg aagatgtgca
      241 cgtcaaggcg aagcgcgtac cgaaagacaa aaaagtgttt accgatgcgc gtgccgtatc
      301 gacccgtcag gatatattca aatccagcga aaacctcgac aacatcgtac gcagcatccc
      361 cggtgcgttt acacagcaag ataaaagctc gggcattgtg tctttgaata ttcgcggcga
      421 cagcgggttc gggcgggtca atacgatggt ggacggcatc acgcagacct tttattcgac
      481 ttctaccgat gcgggcaggg caggcggttc atctcaattc ggtgcatctg tcgacagcaa
      541 ttttattgcc ggactggatg tcgtcaaagg cagcttcagc ggctcggcag gcatcaacag
      601 ccttgccggt tcggcgaatc tgcggacttt aggcgtggat gacgtcgttc agggcaataa
      661 tacctacggc ctgctgctaa aaggtctgac cggcaccaat tcaaccaaag gtaatgcgat
      721 ggcggcgata ggtgcgcgca aatggctgga aagcggagca tctgtcggtg tgctttacgg
      781 gcacagcagg cgcagcgtgg cgcaaaatta ccgcgtgggc ggcggcgggc agcacatcgg
      841 aaattttggc gcggaatatc tggaacggcg caagcagcga tattttgtac aagaaggcgg
      901 gttgaaattc aattccaaca gcggaaaatg ggagcgggat ttccaaaagt cgtactggaa
      961 aaccaagtgg tatcaaaaat acgatgaccc ccaagaactg caaaaataca tcgaaggtca
     1021 tgacaaaagc tggcgggaaa acctggcgcc gcaatacgac atcaccccca tcgatccgtc
     1081 cagcctgaag cagcagtcgg caggtaatct gtttaaattg gaatacgacg gcgtattcaa
     1141 taaatacacg gcgcaatttc gcgatttaaa caccaaaatc ggcagccgca aaatcatcaa
     1201 ccgcaattat caattcaatt acggtttgtc tttgaacccg tataccaacc tcaatctgac
     1261 cgcagcctac aattcgggca ggcagaaata tccgaaaggg tcgaagttta caggctgggg
     1321 gcttttaaag gattttgaaa cctacaacaa cgcaaaaatc ctcgacctca acaacaccgc
     1381 caccttccga ctgccccgtg aaaccgagtt gcaaaccact ttgggcttca attatttcca
     1441 caacgaatac ggcaaaaacc gctttcctga agaattgggg ctgtttttcg acggtccgga
     1501 tcaggacaac gggctttatt cctatttggg gcggtttaag ggcgataaag ggctgctgcc
     1561 ccaaaaatca accattgtcc aaccggccgg cagccaatat ttcaacacgt tctacttcga
     1621 tgccgcgctc aaaaaagaca tttaccgctt aaactacagc accaataccg tcggctaccg
     1681 tttcggcggc gaatatacgg gctattacag ctcggaaggc gaatttaagc gggcattcgg
     1741 agaaaactcg ccgacataca agaaacattg caacccgagc tgcgggcttt atgaacccgt
     1801 attgaaaaaa tacggcaaaa agcgcgccaa caaccattcg gtcagcatta gtgcggactt
     1861 cggcgattat ttcatgccgt tcgccagcta ttcgcgcaca caccgtatgc ccaacatcca
     1921 agaaatgtat ttttcccaaa tcggcgactc cggcgttcac accgccttaa aaccagagcg
     1981 cgcaaacact tggcaatttg gcttcaatac ctataaaaaa ggactgttaa aacaagatga
     2041 tacattagga ttaaaactgg tcggctaccg cagccgcatc gacaactaca tccacaacgt
     2101 ttacgggaaa tggtgggatt tgaacgggga tattccgagc tgggtcagca gcaccgggct
     2161 tgcctacacc atccaacacc gcaatttcaa agacaaagtg cacaaacacg gttttgagtt
     2221 ggagctgaat tacgattatg ggcgtttttt caccaacctt tcttacgcct atcaaaaaag
     2281 cacgcaaccg accaacttca gcgatgcgag cgaatcgccc aacaatgcgt ccaaagaaga
     2341 ccaactcaaa caaggttatg ggttgagcag ggtttccgcc ctaccgcgag attacggacg
     2401 tttggaagtc ggtacgcgct ggttgggcaa caaactgact ttgggcggcg cgatgcgcta
     2461 tttcggcaag agcatccgcg cgacggctga agaacgctat atcgacggca ccaacggggg
     2521 aaataccagc aatgtccggc aactgggcaa gcgttccatc aaacaaaccg aaacccttgc
     2581 ccgccagcct ttgatttttg atttttacgc cgcttacgag ccgaagaaaa accttatttt
     2641 ccgcgccgaa gtcaaaaatc tgttcgacag gcgttatatc gatccgctcg atgcgggcaa
     2701 tgatgcggca acgcagcgtt attacagctc gttcgacccg aaagacaagg acgaagacgt
     2761 aacgtgtaat gctgataaaa cgttgtgcaa cggcaaatac ggcggcacaa gcaaaagcgt
     2821 attgaccaat tttgcacgcg gacgcacctt tttgatgacg atgagctaca agttttaaag
     2881 gcagcccgcg ttttgtggaa aaccgcaatg ccgtctgaaa gcccttcaga cggcatttgt
     2941 ttccccaaac gcatcatcct gccgcaagcc tatgccaatc cgttttatcg catcggcaac
     3001 tcaaagaaaa atccatttca ttcccacgca gggaagccgg ttgatttcgg ttatttttgg
     3061 ttgtttcggg taatttatga gtcgtcattc ccgcaaaagc gggaatctag acattcaatg
     3121 ctaaggcaat ttatcgaaaa tgactgaaac tcaaaaaact ggattcccac tttcgtggga
     3181 atgacg
//
LOCUS       DAXIDM010000154         3153 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000154 DAXIDM010000000
VERSION     DAXIDM010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3153
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.154"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..2645)
                     /gene="pilC"
                     /locus_tag="ACFOAE_001948"
     CDS             complement(<1..2645)
                     /gene="pilC"
                     /locus_tag="ACFOAE_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilC family type IV pilus tip adhesin"
                     /protein_id="HFC6885358.1"
                     /translation="MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNER
                     NQLEVKQEDSYSTLREKDRERKFDFNANRGGGGSVFFDNTDTLVSRQSGTAVFGTATY
                     LPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYVYTNVICRSHQCPQLVYKTRFSF
                     DNPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISS
                     FSEDNNNQTIVSTTENHPISLGDGQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLG
                     VLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKAGRCINKPNPNPKAQ
                     ALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSL
                     KPLSTSEIKSKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGV
                     VPDTNEWKKVLLPWTVRASNDDNQFKTINQQLNQQKIQYSQRYRIRDNGNRDLGDIVN
                     SPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDTSALKDS
                     TLAKELRTFAEKGYVGDRYGVDGGFVLRQVEWKGQNRVFMFGAMGFGGRGAYALDLSK
                     IDSNNPTAVSLFDVKHDSNNGNNRVELGYTVGTPQIGKTHDGKYAAFLASGYATKDIT
                     SGDNKTALYVYDLESSGTLIKKIDVPDGKGGLSSPTLVDRDLDGTIDIAYAGDRGGKM
                     YRFDLSGNNPNSWTVRTIFEGTKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDKNDE
                     QYIYGIFDDDTAASNVDVKLKGLGGGLLEQHLTQEDKTLFLTDYKRSDGSGDKGWVVK
                     LEAGQRVTVKPTVVLRTAFVTIRKYT"
BASE COUNT          658 a          816 c          833 g          846 t
ORIGIN      
        1 gtatatttgc ggatggttac aaaggcggta cgcaatacca cggtcggttt gacggtaacg
       61 cgctgtccgg cttccaattt cactacccag cccttgtcgc ccgagccgtc ggatcgcttg
      121 taatcggtca ggaataaggt tttatcttcc tgagtaaggt gttgctcgag cagcccacct
      181 cccaaacctt tgagttttac atctacatta ctcgccgccg tatcgtcgtc gaagataccg
      241 taaatatatt gttcgtcgtt tttatcaaca tcttcctcac tcaaatcgct gcccgtaccg
      301 aagataacca cgcgtttgtc tttcagttgg gaaatagcag gcgcggaagt aatcggtttt
      361 gtgccttcaa aaatagtgcg tacagtccaa ctgttcgggt tgttgccgct taaatcaaag
      421 cggtacatct tgccgccgcg atcgccggca taggcgatat cgatcgtgcc gtccaaatct
      481 ctatccacca gcgtggggga cgaaagcccg cccttgccgt cgggtacatc gattttttta
      541 atcagcgtac cgctgctttc caaatcatac acatacagcg cggttttatt gtcgccgctg
      601 gtaatgtctt tagtcgcata accggaggcg aggaaggcgg cgtatttgcc gtcgtgggtt
      661 ttgccgattt gcggcgtgcc gacggtgtag cctaattcca cgcgattatt gccgttatta
      721 ctgtcatgtt tgacatcaaa cagggaaacg gcggtcgggt tattgctgtc gattttgctt
      781 aaatccaagg cgtatgcgcc tctgccgcca aagcccatcg cgccgaacat aaacacgcgg
      841 ttttgccctt tccattcgac ttggcgcaag acaaagccgc cgtccacgcc gtagcggtcg
      901 cccacatagc ctttttcggc aaaggtgcgc agctctttgg cgagggtgga gtctttgaga
      961 gcggaagtgt cgttatcaaa atattggcgc ggcatcgtgc cggggatgta gctgagcttc
     1021 agattgtagc tgcgcttgtc cccgccgctt tgtttgaaga tatgcaccat cccgtcgttg
     1081 gcggaagtag ccaaatactc gccgaccgcc acgatggggc tgttgacgat gtcgcccaaa
     1141 tcgcgattgc cgttgtcgcg gatgcggtat ctttggctgt attggatttt ttgttggtta
     1201 agttgttggt taattgtttt aaattgattg tcatcattgg aagcacgaac cgtccaaggc
     1261 agcaatactt ttttccactc attggtatca ggaacgacgc ccaagtcctt aacaatgccg
     1321 aaagtgttgt tgccgttgtt tacattaaaa ctagtgacct cattgccttg aagtttaatc
     1381 tgctgtacgc cgccatccaa tcggatgacg gtttgccgcc ctgtgaaagt cggctcttta
     1441 cttttaatct ccgacgtact caagggtttg agggaatagc ggcccggttt gcttgtgtca
     1501 tccttgcggg aaaggttttg caggaaaatt tggctgctcg aactgtcggg gtaggtggaa
     1561 accgaagcgg aatacatctg caccttgcca ttttgcacag gtccgaacca cagcgcgggg
     1621 gcagtcagtg ccggcgaaag ggcttgggct ttgggattgg ggttcggttt gttgatgcag
     1681 cggcctgctt tgatttgcgg caggccgagc tcgaccggaa tctgcccggt atctttaatg
     1741 tcccacttag catgaaaacc tagcaagccg ccaagccccg tcctttgtgt cttcacatcg
     1801 atgctcggct tcaagacacc caaccgcact gttttgccgg tgatatcttt aatccctttt
     1861 ttatccagca ggtgcagttt ggcgttcaga taataggcca cggcggtatg ttcgcgctgc
     1921 ccgtcgccaa gggaaatagg gtggttttct gtcgtagaga cgatggtttg attattattg
     1981 tcttcactaa aagaagatat caatctgctg gatgattggc tatttttgac ggtattctcg
     2041 ctgcccaaat tgaaagatac gcccaaccat ggatgatcct tcaatttgta aatgagcgaa
     2101 ttgtcgcggc ttggctctgt gtgcctatcc agcccgcctc ctctttttgc caagtcggga
     2161 ttatcgaagg aaaatcgggt tttatagaca agttgggggc attggtggct tctgcatatg
     2221 acgttggtgt agacgtagcc tgccagcccg gcccgggtgg tatgaatcca atcgacggca
     2281 ttgttgcgct ctttcagagc gttggcatca aaaccggaaa ccttgccgta gggcggcagg
     2341 taggtggctg tgccaaaaac ggcagtaccg ctttgtcggg aaacaagggt atcggtattg
     2401 tcgaaaaaga cagaacctcc accccctctg ttcgcattaa agtcaaattt gcgttccctg
     2461 tctttttccc ttaaggttga atatgaatcc tcctgcttta cctccagctg atttcgttcg
     2521 ttcatgataa tagcgtattt atgggtttgc gccatcgccc cccccccgcc ggtatgggaa
     2581 aacatcaaga tggcggcata aagcgcggta tggcggaaaa cccgcctttt taaagtttta
     2641 ttcatcgtat ttccttttcg gtcaaacccc ccgcccttcg ggcatccgtc cttcggggcg
     2701 gcaggatcag gctttgtccg ggaggggtgc aagcccttcc gaatcagggc ggcgccttat
     2761 gtgccgccct gcgtgttgga acatatttta tcccttaaat cttgcttcgc gggataccgt
     2821 cggcggcagg cgcgccgcaa acggcgggat tcggcaaacc gcccgattcc gcgcccgccg
     2881 aattgctggt tggaaaaccc ctttggcccg gctgccaaag ggggatgttc ggaaaagtaa
     2941 cacgcccctt tggccggatg caatgtatag ggttaccgca ttattctacc cttgcgcgct
     3001 gatcatggta aagcggtttt cggcaatccg caaccgcctc cttggcccgc cattgccgcg
     3061 aaagcgggaa tccggaacgt aaaatctcaa aaaaaccgtt ttatccggca agtttgcccg
     3121 ccggcaggcc cgccattgcc gcctgcgcgg caa
//
LOCUS       DAXIDM010000155         3106 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000155 DAXIDM010000000
VERSION     DAXIDM010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.155"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..460
                     /locus_tag="ACFOAE_001949"
     CDS             <1..460
                     /locus_tag="ACFOAE_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HFC6885359.1"
                     /translation="YISTINVDIGQQVEPSKLLLSIVPEQTELVANLYIPSKAVGFIK
                     PKDKVVLRYQAYPYQKFGHATGEIISVARTALGKQKLSGLGIIFTNPTLLNEPAYLVK
                     VKLEKQTIKAYGENKPLQIGMILEADILHERKKLYEWVLDPLYSISGKIN"
     gene            463..2550
                     /locus_tag="ACFOAE_001950"
     CDS             463..2550
                     /locus_tag="ACFOAE_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003700725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HFC6885360.1"
                     /translation="MDYLSRLSFGFNKKLPVILQTEVAECGLACLTSILSYYGFHTDL
                     RTLRQKYTLSLKGANLADIMRFGNEMNLTPRALRLELDELSNLQLPCILHWNLNHFVV
                     LCSISKDSIVIMDPAVGMRKIKMDEVSQKFTGIALELFPNTHFEEKKETKKIKILSLL
                     RGISGLKRSLIQMLILAISLEVFALVSPFFMQWVIDHVIVTADKNLLLTLTLGFGLLA
                     ILQQLISLLQAWVGMHLSTTLNLQWKANIFKRLLDLPNDYFSKRHLGDVISRFGSIDH
                     IQETLTSTFFVLVLNSLMAVFTFVLMTIYSTQLSLIVLLTLVLYILIRWLAYYPLRNA
                     TEENIVHEAKQNSYFMETIRGIQSVKLFDKHYQRHGTWMSLFVNTVNTKLTTDKLSAL
                     FEFSNKLLFSMENIIIIYLGASAILDGSFTVGVLMAFLAYKGQFESRTASLVDQYIQI
                     KMLGLHAERLADITLNETETEIIKYNHIPKLDNEQLVLKVENVSFRYADNEPYLFENI
                     NLEFKDNEAVVLTGQSGRGKSTLLNILTGSLKPETGTVSINGHDIYQVSPSFIRGLSG
                     IVRQDDVLFAGSIGENISFFDESPNMELIEQCAKMAQIHDDILKMPMGYETLIGDMGN
                     ILSGGQKQRVILARALYKRPKILFLDEASSHLDVENEQKINHNLKSLGIMKIMVAHRQ
                     ETIQSADKILNLG"
     gene            complement(2632..2934)
                     /locus_tag="ACFOAE_001951"
     CDS             complement(2632..2934)
                     /locus_tag="ACFOAE_001951"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885361.1"
                     /translation="MKDFDEVCEKWEKSFKENGKEIEYNQKYSRIYGEVRGAGFNGDI
                     GEKLHRCAVMEWAENETVKLAQKWEQEQKKQQIQQKKETEKSPKHKASRDDWEMER"
     gene            3001..>3106
                     /locus_tag="ACFOAE_001952"
     CDS             3001..>3106
                     /locus_tag="ACFOAE_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006249760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6885362.1"
                     /translation="MRKSRLSQYKQNKLVELFVAGATARTAAELVGVNK"
BASE COUNT         1022 a          543 c          530 g         1011 t
ORIGIN      
        1 ttatatatca acaattaatg ttgatatagg gcaacaagtt gaaccgtcta aattgctgtt
       61 aagcattgtc cctgaacaaa ctgaattggt cgccaatctt tacataccca gtaaagctgt
      121 tggttttatt aaaccgaaag ataaagttgt tttacgttac caagcgtacc cttaccaaaa
      181 atttggacat gccacaggag aaattatttc agttgccaga actgctctcg gtaaacaaaa
      241 gctatcaggt ttaggtatca ttttcactaa cccaacctta ttaaatgaac ctgcctatct
      301 tgtgaaagtt aaattggaaa aacaaacgat taaagcatac ggagaaaaca agccgcttca
      361 aattggcatg attttagaag cagatattct ccatgaacga aaaaaattgt acgaatgggt
      421 acttgaccca ctttacagca tttcaggaaa aatcaattaa aaatggatta tttatcaaga
      481 ctgtcctttg gatttaacaa aaagctacct gtcattctgc aaacagaagt tgctgaatgt
      541 ggtttagcat gcctgacatc catcttgtcc tattatggct ttcacactga tttaagaacg
      601 ttacgccaaa aatacaccct gtcattaaag ggcgcaaatc ttgcagacat catgagattt
      661 ggcaatgaaa tgaatttaac gccacgagct ttgcgtttag agttagatga gctgtcaaat
      721 ttacaactac cctgcattct ccattggaac ttaaaccatt ttgttgtact ttgttccatt
      781 tccaaagaca gtatcgtcat tatggaccct gctgtcggta tgcgaaaaat caaaatggac
      841 gaagtttcac aaaaattcac agggattgcc ctagaattat tccccaatac ccattttgaa
      901 gagaaaaaag aaacaaagaa aatcaaaata ttatctctat taagggggat ttcaggctta
      961 aaacgctctt taattcaaat gcttatatta gctatttctt tggaagtctt tgcattggtt
     1021 agtccattct ttatgcaatg ggtaatagac catgtcattg taactgctga taaaaattta
     1081 ttactgaccc ttactttggg atttggttta ctggctatcc tgcaacagtt aattagcctg
     1141 ttacaagcat gggtaggtat gcacctatct acaactctta atttacaatg gaaagccaat
     1201 atatttaaaa ggttacttga cttacctaat gactatttca gtaaacgaca tttaggagat
     1261 gtgatttcaa gatttggttc aatagatcat atccaagaaa cactaacttc tacttttttt
     1321 gttttagttt taaatagctt aatggctgtt tttactttcg tgttaatgac aatttacagc
     1381 actcaattat cgctgattgt tcttttaaca cttgttttgt acatactaat tcgttggctt
     1441 gcatattacc cattaagaaa tgcaacagaa gaaaatattg ttcatgaagc caaacaaaac
     1501 tcatatttca tggaaaccat tcgtggtatc caatcagtta aattatttga taaacattat
     1561 caaagacatg gcacttggat gagcctattt gtgaatacag tcaataccaa gctgacaaca
     1621 gataaactct ctgctttatt tgaattttca aataaactgt tgtttagcat ggaaaatatt
     1681 atcataattt atcttggtgc aagcgcaatt ttagatggtt catttacagt cggtgttctg
     1741 atggcttttt tggcttataa agggcaattt gaaagcagaa cagcttctct cgttgaccaa
     1801 tacatccaaa tcaaaatgtt agggcttcat gctgaacgtt tggctgacat tactttaaat
     1861 gaaacagaaa ctgaaattat taagtataat catataccta aattagataa tgaacaactg
     1921 gttcttaaag ttgaaaacgt ctcattcaga tatgctgata atgagccata tctttttgaa
     1981 aacattaatt tggaatttaa agataatgaa gcagttgttt taacaggaca atctggtcgg
     2041 gggaagtcca ctttgttaaa cattttaaca ggtagcctaa aacctgaaac tggtacagtt
     2101 agtattaatg ggcatgatat atatcaagtt tctccatcct ttattagggg attgagcggg
     2161 attgttcgcc aagatgatgt cctttttgca ggttctattg gggaaaatat ttcatttttt
     2221 gatgaaagcc caaatatgga gctcattgaa caatgtgcaa aaatggcaca aatacatgac
     2281 gatatactta aaatgccaat gggctatgag accttgattg gcgatatggg aaatatctta
     2341 tcaggtggac aaaagcagag agttatcttg gctcgtgcat tgtataaacg acccaaaatt
     2401 ctatttttag acgaagcaag tagccattta gatgtagaaa atgaacaaaa aattaaccat
     2461 aacctaaaaa gtcttggtat tatgaaaata atggttgcac accgccaaga aacaattcaa
     2521 tcggcagata aaattctgaa tttaggttga acagaacaag acttcatttt tctttaacaa
     2581 aaagtgaagt cttttttcaa ataatttaat agaatacatg aaaatagcgg tttaacgttc
     2641 catttcccaa tcatcacgac tggctttgtg ttttggcgat ttttcagttt cctttttctg
     2701 ttgaatttgt tgttttttct gctcttgttc ccatttttgg gctaatttca cggtctcatt
     2761 ttcagcccat tccatcacgg cacaacgatg tagcttttct ccgatatcgc cattaaagcc
     2821 agctccacga acttcaccat aaattcttga atatttttga ttatattcaa tttcttttcc
     2881 attttcttta aaggatttct cccacttttc acaaacttca tcaaaatctt tcaaagggat
     2941 attttttaag gggctgtcct agataactag ggaaattcaa attaagttag aattatccct
     3001 atgagaaaaa gtcgtctaag ccagtataaa caaaataaac tcgttgagct atttgtcgca
     3061 ggtgcaactg caagaacggc agcagagtta gtaggcgtta ataaaa
//
LOCUS       DAXIDM010000156         3079 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000156 DAXIDM010000000
VERSION     DAXIDM010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.156"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            86..1315
                     /gene="sstT"
                     /locus_tag="ACFOAE_001953"
     CDS             86..1315
                     /gene="sstT"
                     /locus_tag="ACFOAE_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFC6885363.1"
                     /translation="MAFGKSLFHAIGRVSLVRQIAAGLALGIVIGSVSPQLGLAAGLF
                     GSLFVGALKAVAPVLVFILVAATIAQHQKGNKAHIRPIIVLYLIGTFSAALTAVIAGM
                     VFPTHIVLAGAGDVSAAPPSGIVEVLKSLLMNLVANPINAIANANYIGILAWALVLGA
                     ALRNHGSDVTRQVVADLAEAVSTVVKWIIRFAPLGIFGLVSSTIAETGFGALAGYAKL
                     LAVLLGCMAFIALVVNPAIVWWKIRRNPYPLVFTCLRESGVYAFFTRSSAANIPVNMA
                     LAKKLGLHEDTYSISIPLGATVNMGGAAITITVLAMAAAYTQGIQVDFATALLLSLVA
                     TVSACGASGVAGGSLLLIPLACSLFGISNDVAMQVVAVGFIIGVIQDSAETALNSSTD
                     VLFTAAADLGRQRNRAE"
     gene            1427..2707
                     /locus_tag="ACFOAE_001954"
     CDS             1427..2707
                     /locus_tag="ACFOAE_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012222163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferrin-binding protein-like solute binding
                     protein"
                     /protein_id="HFC6885364.1"
                     /translation="MFKRSVIAMACIVALSACGGGGGGSPDVKSADTLSKPAAPVVAE
                     KETEVKEDAPQAGSQGQGAPSTQGSQDMAAVSAENTGNGGAATTDKPKNEDEGPQNDM
                     PQNAGNTAAQGTNQAENNQVGGSQNPAPSSNPNATNGGNFGRVDLANGVLIDGPSQNI
                     TLTHCKSDSCNGDNLLSEEAPSKSEFEQLSDEDKIKKYKKDGEKFTGLVADRLQMKGT
                     NQYIIFYKPKTTSSARFRRSARSRRSLPAEMPLIPVNQADTLIVDGEAVSLTGHSGNI
                     FAPEGNYRYLTYGAEKLPGGSYALRVQGEPSKGEMLAGTAVYNGEVLHFHTENGRPSP
                     SRGRFAAKVDFGSKSVDGIIDSGDGLHMGTQKFKAAIDGNGFKGTWTENGGGDVSGKF
                     YGPAGEEVAGKYSYRPTDAEKGGFGVFAGKKEQD"
     gene            complement(2782..2997)
                     /locus_tag="ACFOAE_001955"
     CDS             complement(2782..2997)
                     /locus_tag="ACFOAE_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019271201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885365.1"
                     /translation="MFKLGVYACLGLFAGWVLLLIVQLWFSFLKAELFFKITLTMAGL
                     FVIILAALLVFGQYFSEKKMKDDGFIN"
     gene            complement(2990..>3079)
                     /locus_tag="ACFOAE_001956"
     CDS             complement(2990..>3079)
                     /locus_tag="ACFOAE_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HFC6885366.1"
                     /translation="VVTMEKDLRRMLLFFKREAYVVILERDRV"
BASE COUNT          738 a          747 c          883 g          711 t
ORIGIN      
        1 acagccgaaa aataaaaaaa cacagagaat gagttttctt ttaaaataca acatttttta
       61 acatatcaca acataaggaa gaattatggc gttcggcaaa tccttatttc atgcgatcgg
      121 ccgcgtcagc ctggtcaggc agattgccgc cggtttggcg ttgggcatcg taatcggttc
      181 ggtttccccg caactgggct tggcggcagg cttgttcggc agcctgtttg tcggcgcgct
      241 caaagcggtc gcgccggttt tggtatttat tttggtggcg gccacaatcg cgcagcacca
      301 aaaaggcaac aaggcgcata tcaggccgat tatcgtcctt tacctcatcg gtacgttttc
      361 cgcagccctg accgccgtca tcgccggtat ggttttcccg acgcacattg ttttggcggg
      421 cgcgggcgat gtgtccgccg cgccgccttc cggcattgtg gaagtgttga aatcgctgct
      481 gatgaacctg gtcgccaacc cgattaacgc gattgccaat gccaactata tcggcattct
      541 ggcttgggct ttggttttgg gcgcggcgtt gcggaatcac ggttcggacg ttacgcggca
      601 ggtcgttgcc gatttggcgg aagcggtttc caccgtcgtg aaatggatta tccgttttgc
      661 ccctttgggc attttcgggc tggtgtcgtc cacaatcgcg gagacgggtt tcggcgcgct
      721 ggcgggttat gcgaagctgc ttgcggtact gttgggctgt atggcgttta tcgcgctggt
      781 ggtcaatccc gccatcgtgt ggtggaaaat ccgccgcaac ccttatccgc tggtgtttac
      841 ctgcctgcgc gaaagcggcg tgtatgcctt ctttacccgt tcttccgccg ccaatatccc
      901 cgtgaatatg gctttggcga aaaaactggg gctgcacgaa gacacttatt cgatttccat
      961 cccgttgggg gcgaccgtca atatgggcgg cgcggcgatt acgattaccg ttttggctat
     1021 ggcggcggcg tacacccaag gcatacaggt tgattttgcc accgcgctgc tgttgagcct
     1081 ggtggcgacg gtcagcgcgt gcggcgcgtc cggtgtggcg ggcggttcgc tgctgctgat
     1141 tccgctggcg tgcagcctgt tcggcatcag caacgatgtc gctatgcagg tggtcgccgt
     1201 cggctttatc atcggcgtga ttcaggattc ggcggaaacg gcgttgaatt cttcaaccga
     1261 tgttttgttt accgccgccg ccgatttggg cagacagaga aaccgggcgg aataaaccaa
     1321 gctatgccgt ctgaagccct tttggcgttc agacggcata tttttacaat tttatgggca
     1381 tatggcggaa acaataccgg ctgccttgaa tatgaaggag atgatgatgt ttaaacgcag
     1441 tgtgattgca atggcttgta ttgttgccct ttcagcctgt gggggcggcg gtggcggatc
     1501 gcccgatgtt aagtcggcgg acacgctgtc aaaacctgcc gctcctgttg ttgctgaaaa
     1561 agagacagag gtaaaagaag atgcgccaca ggcaggttct caaggacagg gcgcgccatc
     1621 cacacaaggc agccaagata tggcggcagt ttcggcagaa aatacaggca atggcggtgc
     1681 ggcaacaacg gacaaaccca aaaatgaaga cgagggaccg caaaatgata tgccgcaaaa
     1741 tgccggcaat acggctgccc aaggtacaaa tcaagccgaa aacaatcaag tcggcggctc
     1801 tcaaaatcct gccccttcaa gcaatcctaa tgccacgaat ggtggcaatt ttggaagggt
     1861 tgatttggct aacggtgttt tgattgacgg accgtcgcaa aatataacgt tgacccattg
     1921 taaaagcgat tcttgtaatg gtgataatct attaagcgaa gaagcaccgt caaaatcaga
     1981 atttgaacaa ttaagtgatg aagacaaaat taagaaatat aaaaaagatg gagaaaagtt
     2041 taccggtttg gttgctgata ggttacagat gaaaggaacc aatcaatata ttatttttta
     2101 caaacctaaa accacttcat ctgcgcgatt caggcgttct gcacggtcta ggaggtcgct
     2161 tccggctgag atgccgctga tccccgtcaa tcaggcggat acgctgattg tcgatgggga
     2221 agcggtcagc ctgacggggc attccggcaa tatcttcgcg cccgaaggga attaccggta
     2281 tctgacttac ggggcagaaa aattgcccgg cggatcgtat gccctccgtg ttcaaggcga
     2341 accttcaaaa ggcgaaatgc tcgcgggcac ggcagtgtac aacggcgaag tgctgcattt
     2401 tcatacggaa aacggccgtc cgtccccgtc cagaggcagg tttgccgcaa aagtcgattt
     2461 cggcagcaaa tctgtggacg gcattatcga cagcggcgat ggtttgcata tgggtacgca
     2521 aaaattcaaa gccgccatcg atggaaacgg ctttaagggg acttggacgg aaaatggcgg
     2581 cggggatgtt tccggaaagt tttacggccc ggccggcgag gaagtggcgg gaaaatacag
     2641 ctatcgccca acagatgcgg aaaagggcgg attcggcgtg tttgccggca aaaaagagca
     2701 ggattgatgc cgatgccgcc tgaagcgggg gcgttcagac ggcattgtga tgtttggggt
     2761 ggggtccggt tcaagtccgc atcagttgat aaacccgtcg tctttcattt tcttttcgga
     2821 aaaatactgg ccgaatacca gcagggcagc gaggatgatg acaaacagtc ccgccatagt
     2881 cagagtgatt ttgaaaaaca attccgcttt gagaaaagaa aaccagagtt gcacaatcag
     2941 cagcagcacc cagccggcaa acagtccgag acaggcataa acgccgagct taaacacggt
     3001 cccgctccaa aatgacgacg taggcctcgc gtttgaaaaa cagcagcata cggcgcaaat
     3061 ctttttccat cgttacgac
//
LOCUS       DAXIDM010000157         3052 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000157 DAXIDM010000000
VERSION     DAXIDM010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 3052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3052
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.157"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(160..2388)
                     /locus_tag="ACFOAE_001957"
     CDS             complement(160..2388)
                     /locus_tag="ACFOAE_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002258624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0030256 - type I protein secretion system
                     complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0030253 - protein secretion by the type I
                     secretion system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HFC6885367.1"
                     /translation="MRSAVLFIYFFLLNIFLFQPAVIHIQSNYILFMSIVSAPLPALS
                     ALIILAHYHGIAANPADIQHEFCTSAQSDLNETQWLLAAKSLGLKAKVVRQPVKRLAM
                     ATLPALVWCDDGNHFILAKTDGGGEHAQYLIQDLTTNKSAVLSFAEFSNRYSGKLILV
                     ASRASVLGSLAKFDFTWFIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVL
                     VHRGFSTLDVVSVALLVVSLFEIVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLS
                     YFEHRRVGDTVARVRELEQIRNFLTGQALTSVLDLAFSFIFLAVMWYYSSTLTWVVLA
                     SLPAYAFWSAFISPILRTRLNDKFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWD
                     NQLAAYVASGFRVTKLAVVGQQGVQLIQKLVTVATLWIGARLVIEGKLTVGQLIAFNM
                     LSGQVAAPVIRLAQLWQDFQQVGISVARLGDILNAPTENASSHLALPDIRGEITFEHV
                     DFRYKADGRLILQDLNLRIRAGEVLGIVGRSGSGKSTLTKLVQRLYVPEQGRVLVDGN
                     DLALAAPAWLRRQVGVVLQENVLLNRSIRDNIALTDTGMPLERIIEAAKLAGAHEFIM
                     ELPEGYGTVVGEQGAGLSGGQRQRIAIARALITNPRILIFDEATSALDYESERAIMQN
                     MQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRIVEAGTQQELLAKPNGYYRYLYDLQ
                     NG"
BASE COUNT          881 a          834 c          679 g          658 t
ORIGIN      
        1 agatgagtga aaaagaagtg caggctgcct aaaaagacag aaaaagtctt tcaggcagcc
       61 tgcactttgg tttcatttca gtcagtaaac ccagtaaacg acggtctgaa aacgcagaac
      121 gttacgaaaa aagcagccta cacgcccatc ccccgccttc tacccgttct gtaaatcata
      181 cagatagcgg taatatccgt tcggcttcgc cagcaattcc tgctgtgttc ccgcttccac
      241 aatcctgcct ttatccatgg caatgatccg gtgtgccgtt ttaacggtgg acagacggtg
      301 ggcgataatc agcaccgtcc ggttggcgca aatggcctgc atgttctgca taatcgctcg
      361 ttcactttca taatccagcg cgctggtggc ttcgtcaaaa atcagaatgc gcggattggt
      421 gattaacgcg cgggcaatcg caatacgctg ccgctgtccg cccgacaagc cggccccttg
      481 ttcgcccacc acggtgccgt agccttccgg cagctccata ataaactcgt gtgcgcccgc
      541 cagtttggct gcttcgataa tgcgttccag cggcataccc gtatccgtca gcgcgatatt
      601 gtcgcgtatg ctgcggttga gcagcacatt ctcctgcaag accacgccga cctgccgccg
      661 cagccaggca ggagcggcca aagccaaatc gttgccgtcc accaacaccc gtccctgctc
      721 cggtacatac agacgctgca ccaatttggt gagtgtggat ttgcccgacc ccgaacgtcc
      781 cacaatcccc agcacttccc ccgcccgaat ccgcaggttc aaatcctgca aaatcagcct
      841 gccgtccgcc ttatagcgga aatcgacatg ttcgaacgta atctcccccc ggatatcggg
      901 caaagccaaa tgcgaagacg cattctcggt cggcgcattc agaatatccc ccaaacgcgc
      961 caccgaaatc cccacctgct ggaaatcctg ccacaactgc gccaaacgga taacaggcgc
     1021 cgccacctgt cccgagagca tattaaacgc aatcagctgc cccaccgtca gcttgccctc
     1081 aattaccagc cgtgcgccaa tccacaacgt cgccaccgtc accagcttct gaatcagctg
     1141 caccccctgc tggccgacca ccgccaactt cgttacccga aatcccgaag ccacataagc
     1201 cgccaactga ttgtcccaac gctgcgtcat ctgcggctcc accgccatcg cctttaccgt
     1261 acccaccgca gtgatgcttt ctactaaaaa cgactggttg tctgcattgc gcgcgaactt
     1321 atcgttcaga cgcgtccgca gtatcggact gataaatgcc gaccaaaacg cataggcagg
     1381 caacgaagcc aataccaccc aagtcagagt ggagctgtaa taccacatca ccgccagaaa
     1441 gataaacgaa aacgccaaat ccaacaccga agtcagcgcc tgaccggtca agaaattgcg
     1501 aatctgctcc aattcccgca cccgagccac cgtatcaccc actcgtctgt gctcgaaata
     1561 ggataaaggc agggaaagca gatgccggaa caaacgcgcg cccaattcca catcaatacg
     1621 tgaagtcgta tgtgcaaaca gatacgtccg caaaccgccc aacacaatct caaacagcga
     1681 caccaccaac aaagccaccg acaccacatc caaagtagag aatccccgat gtaccagcac
     1741 cttgtccatc accacttgga aaaacagagg cgtaatcagc gcaaacagct gcaacaccac
     1801 cgacaccacc aatacttcaa aaaacaaccg gcggtatttg attaccgccg gaataaacca
     1861 ggtaaagtca aactttgcca aactgcccaa taccgaagcg cgggaagcaa ccaatatcag
     1921 tttgcccgaa tatctgttag aaaattcggc aaaagacaat accgcagact tattcgtagt
     1981 taaatcctgt attagatatt gggcatgctc acccccaccg tctgttttag ccaaaataaa
     2041 atggttgccg tcatcacacc ataccaatgc aggtaaggtc gccatagcca aacgtttgac
     2101 aggctggcgg actacctttg ccttcaatcc caaagatttg gcggctaaca gccattgcgt
     2161 ttcatttaaa tcgctctgtg cggaagtaca aaattcatgc tgtatatcgg caggattggc
     2221 ggcaatgccg tggtaatggg cgaggatgat gagggcggaa agggcgggga gcggtgcgga
     2281 tacgatagac ataaataaaa tatagttaga ttggatgtgg ataacggctg gctggaaaag
     2341 gaatatatta agtagaaaga aatatataaa taaaacagca gaacgcattg taaggatata
     2401 tatgggaatt gtaaagagaa agtatggaaa agttctcgtt tcaggaaggt aaaacggctt
     2461 aggaatcgag ttagatgagg atgcctcgca cctctcgtgc ctcctgcata ccgttaagga
     2521 acagggttaa ggtgcaggct gctccgaact ctgttgcggt cggataatgt tattttttgt
     2581 gtttcaggca gcctgaaata tctgtatatt tttgttttaa atagatttta aagattgata
     2641 actgttcttg acgatttttc aagaaaggag taaagtgact tattatcaat gacaagcaac
     2701 gcgcgaagtg acaaggaaaa ctatctactt aaattctaag gaggcttcga atatcataaa
     2761 ccaatcagaa acatagagat aaaaattatg tacaaatata atcctcttat acaatttatt
     2821 gcacagttga ttatgtctta tggagcaagc atagggtggg cacttgctgc ccacgcgttt
     2881 catatttcaa ggcagcctga aactgtgtgg gcataatgcc taccctacat cccaaaaaaa
     2941 caagcgcagc ctgcgtgtgt agggtgcgaa ctttcggcag gcagacacgc ggttttatag
     3001 tttcaagctg agttgggatg cttaagataa agtacaaaac cttaaaaaat aa
//
LOCUS       DAXIDM010000158         2941 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000158 DAXIDM010000000
VERSION     DAXIDM010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2941
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.158"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(127..1437)
                     /locus_tag="ACFOAE_001958"
     CDS             complement(127..1437)
                     /locus_tag="ACFOAE_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFC6885368.1"
                     /translation="MTDLFAREPDAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEG
                     GKPHSMLLWGPPGVGKTTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQG
                     RATILFVDEVHRFNKAQQDAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQ
                     PLSSDDLKKLIAKVLALPEYQEFTIETDAQKLLVNTADGDARRLLNLLEQLLRAADTR
                     RLKNLTAEFLADSLGAQIRRFDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGG
                     TDPRYLARRIVRIAWEDIGLADPRAFQIANDAAATFERLGSPEGELALAQAVLYLAAA
                     AKSNAGYKAYNQMRHFVKENASDEVPVHLRNAPTKLMKELGYGREYRYAHDEPNAYAA
                     GESYMPDGLDEPDFYQPVPRGLEIKIGEKLEWLKSLDEEVLKAK"
     gene            1749..2171
                     /locus_tag="ACFOAE_001959"
     CDS             1749..2171
                     /locus_tag="ACFOAE_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014580802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885369.1"
                     /translation="MEWVSLFSDPQRDDDSLITLKDEKITVKNYIVPWWKKGENFRKL
                     ELITTGKNDNGNLTVNGIYGIQSFADSQLGYTPELLVKSNNDILFKNNFQSVDVKPHS
                     GNIHLDAKGKIQFNLNVPDVDGVQDVASGKKYRQTIVP"
     gene            2257..2754
                     /locus_tag="ACFOAE_001960"
     CDS             2257..2754
                     /locus_tag="ACFOAE_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
                     /protein_id="HFC6885370.1"
                     /translation="MNVKVHKDTHHFGIHNLNNTDVHLTAEDSDNVIEIKGELADLMP
                     TGNVESTSFLRGIETAFKSNTVLTGNNNKISIATEGKGLGLGVNGLQSNSPYSGHTTG
                     IFINNQSSDLTQPSLDGISTIKLKAVKGNNEVDLNVKNHASVKGIIASHSAKATLEAE
                     GDNIV"
     gene            2859..2941
                     /locus_tag="ACFOAE_001961"
                     /pseudo
     CDS             2859..2941
                     /locus_tag="ACFOAE_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006248742.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter"
BASE COUNT          813 a          707 c          701 g          720 t
ORIGIN      
        1 ttaatccact ataccacgtt gtctttattg gctttatcaa taaacaggat aagacctgaa
       61 aaaaagccga tacgcctttt tggtgtaccg gctttgccat actgttctgc ttcagacagc
      121 attgcttcat tttgccttta atacttcttc gtccagcgat ttcaaccatt ccagcttttc
      181 gccgattttg atttccaacc cgcgcgggac gggttggtag aagtccggtt cgtccaagcc
      241 gtcgggcata tagctttcgc cggcggcgta ggcgttcggt tcgtcgtggg cgtagcggta
      301 ttcgcgtccg tagcccaatt ccttcatcag cttggtcggg gcgttgcgca ggtggacggg
      361 cacttcgtcg ctagcgtttt ctttgacgaa gtggcgcatt tggttgtatg ccttgtagcc
      421 cgcgttggat ttcgcggcgg cggcaagata caataccgct tgcgccaaag ccagttcgcc
      481 ttcgggcgag cctaagcgtt cgaaggtggc ggcggcatcg ttggcgattt ggaaggcgcg
      541 cgggtcggca agcccgatgt cttcccaagc gatacgcacg atgcggcggg cgaggtagcg
      601 cgggtcggtg ccgccgtcga gcatacggca gaaccaatac agcgcggcgt tcggatgcga
      661 accgcgcacg gatttgtgca gggcggagat ttggttgtag aaactctcgc cgcctttgtc
      721 gaaacggcgg atttgcgccc cgagactgtc ggcgagaaat tcggcggtta agtttttcag
      781 acgacgtgta tcggcggcgc gtaaaagttg ttccaacaaa ttcaacaatc tgcgcgcatc
      841 accgtcggcg gtattcacga gtaatttttg cgcatccgtt tcaatcgtaa actcttggta
      901 ttcaggcaaa gccaatacct tggcaatcag ctttttcagg tcgtctgaag acaagggttg
      961 caaaacatac acctgagcgc ggctcaacag cgcgggattg acttcaaacg acggattttc
     1021 cgtcgtcgca ccaataaagg ttagcaaacc gctttcgaca tgcggcaaaa acgcgtcctg
     1081 ctgcgccttg ttgaagcggt ggacttcatc gacaaacaaa atcgtcgcgc gtccctgctg
     1141 caaagcgatt tcggctttat cgattgcctc gcggatgtcc ttcacgccgg aaaacacggc
     1201 ggaaacaggc aaaaactggg cattgaaact ctgcgccaaa atccgcgcca acgtcgtctt
     1261 gcccacgccc ggcggccccc acagcaacat agaatgcggc ttgccgcctt ctaccgccac
     1321 gcgcaaaggt ttaccttcgc cgatgaggtg ttcctgcccc accacgtcgt caagcgtatg
     1381 cggacgcaat cgttcggcaa gcggcgcgtc gggttctcgg gcaaacaaat cggtcataac
     1441 ggctccgtca acaggttttc aaacaatatg attatacggc agggaacggc ggcgtgccgc
     1501 atacggattc cgcccctccg tttgccttaa gccgatatta ggcgcatact ggaaaagacg
     1561 agagacttca cacaatatat ccggcacgga gaccgattcc gcatcggcat gacaataccc
     1621 aaatcagcgt ttcaattaaa cattaaggag actaaaatag aaaatttgct ttatctacca
     1681 ttgctttgtt gattcaatcg gcattatgtt ttgaggcgga agcccatgaa tatactaata
     1741 ttcaagagat ggaatgggtg tctttatttt ctgatccgca aagagacgat gatagtctta
     1801 taacccttaa agatgaaaaa atcactgtaa aaaactatat tgtgccttgg tggaaaaaag
     1861 gtgaaaactt tagaaaatta gaacttatta ccactggtaa aaatgataat ggaaatttaa
     1921 cggtaaatgg aatttacggc atccaatctt ttgcagactc tcaattggga tatacgcctg
     1981 aattattggt aaaaagcaat aatgatattc tatttaaaaa taatttccaa tctgttgacg
     2041 tgaagcccca ttccggaaat atccatttgg atgccaaagg aaaaattcaa tttaatttga
     2101 atgttcccga tgttgatggg gtacaagatg tagccagtgg aaaaaaatac cgacaaacaa
     2161 tagtgcctta gtgcggtatg tcaacactat cagccccccg atgaaaatga caaaggcagc
     2221 atatcctttc attcaaaaac aggcaatttg ttcaatatga acgttaaagt tcataaagac
     2281 acacaccatt tcggtattca caacctcaac aataccgatg ttcatctgac tgccgaagac
     2341 agcgataatg tgattgagat taaaggggaa ctcgccgacc ttatgccgac aggaaatgtt
     2401 gagagtacaa gttttttaag gggcattgaa acggctttta aatccaatac cgtattaacg
     2461 gggaataaca ataaaatatc catcgccact gagggcaagg gcttgggatt gggcgtaaat
     2521 ggtctccagt ccaactcccc ctattccgga cacacgacgg gcattttcat caataatcaa
     2581 tcaagcgacc ttacccaacc ttcccttgat ggcatcagca ccatcaaact caaagccgtc
     2641 aagggaaata atgaagttga tttaaatgta aaaaaccacg cctccgtaaa aggcattatc
     2701 gcgtcgcatt ctgcaaaagc aacgcttgaa gccgaagggg acaatattgt ctaggttaaa
     2761 aatccggaca ccaatacggc tttaatcgat gctttgaaaa aacaataccc caatgcttcg
     2821 aaagaactat acagggtggg ggttcaatcc acgactggaa cagtacgcat ttcgccaaac
     2881 ggcaaaatcg cattaacgga attgaaaact tttggaattg tacaaaacgg catttgcgtc
     2941 a
//
LOCUS       DAXIDM010000159         2852 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000159 DAXIDM010000000
VERSION     DAXIDM010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2852
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.159"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(1..111)
                     /locus_tag="ACFOAE_001962"
                     /pseudo
     CDS             complement(1..111)
                     /locus_tag="ACFOAE_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225556.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            complement(110..568)
                     /locus_tag="ACFOAE_001963"
     CDS             complement(110..568)
                     /locus_tag="ACFOAE_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002257756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885371.1"
                     /translation="MLTKLKILLFLFLFVFVLAINLLFFFFSSDIESFGNYQFEYVYD
                     KGWPANYILVMKDGNEGNFDKIISGLVLEYYKEDDNIYFSYIDGQGFASDSCYYKPEI
                     LYGKIILNKNHIININSMEKNNFLSEDKIMKGTRNWLADPKNKCNIQTLD"
     gene            complement(1132..1335)
                     /locus_tag="ACFOAE_001964"
     CDS             complement(1132..1335)
                     /locus_tag="ACFOAE_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885372.1"
                     /translation="MLSLEIQQEGFTIGGGLVLGGCAGAHLARKEPLILTGKTGAGAS
                     AIANASIGYQWTVNLSEPKEGAK"
     gene            complement(1898..2833)
                     /locus_tag="ACFOAE_001965"
     CDS             complement(1898..2833)
                     /locus_tag="ACFOAE_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity 49 family protein"
                     /protein_id="HFC6885373.1"
                     /translation="MGHNMMTTQKWYEHITNVIIGNTANFNSGCLDSIDYVDERKGVP
                     LAAMQHIFMDVRAAASHAYLFEHDLKKFKQYAYVAGKLGVLLSVNSTDPEPFFFPCDM
                     LNIQNPMFLMLMSDSPQLREFLVRNIDNIANDTEAFINRYDLNRHMIYNTLLMVEGKQ
                     LDRLKQRSEKVLAHPTPSKWLQKRLYDYRFFLAFAEQDAEAMKAALEPLFDKKTARMA
                     AKETLSYFDFYLQPQIVTYAKIASMHGFDLGIDHEIAPRDLTVYDPLPADEYQDIFDF
                     MKQYDLSYPYEYLQDWIDYYTFKTDKLVFGNAKRE"
BASE COUNT          864 a          567 c          515 g          906 t
ORIGIN      
        1 gattttaagc tgttgagacg gtgtgccgaa gttaaatcga aattcgcatt ctttcaagaa
       61 cagcgggaaa gatttgcaat cgattccgtt gtattttcgc aagacacgtt tagtctagag
      121 tctgtatatt acatttattt ttagggtctg ctagccaatt tcttgttccc ttcattattt
      181 tatcttctga aagaaaatta tttttttcca tgctattaat attaatgata tgatttttat
      241 ttaaaataat ttttccatat aaaatttccg gtttgtaata gcaagagtct gaagcaaatc
      301 cttgcccgtc aatataagaa aaataaatgt tatcatcctc cttataatat tctaaaacca
      361 atccggatat tattttatca aaattccctt catttccatc tttcatgact aaaatataat
      421 tagcaggcca acctttatcg taaacatatt caaactgata gttcccgaaa ctctcgatat
      481 ccgaactaaa aaagaagaaa agcaaattaa tagccaatac aaaaacaaat aagaacaaaa
      541 atagcaaaat tttcaactta gttaacaata tttacctctc ctttaaattc aatcctgaaa
      601 ggtacccctt accctgggct accaattata gtttccatat ttctaaatat tgtttttaca
      661 ttactttttt ctccccccaa aggaattcat tttaaaatca tgcttttcag gtgctaatcg
      721 atacttacca ttaacatctt taatcacaga tatatttcca tgtatagccc aacgtgaaaa
      781 atctgagtat tatatacagt tataccttac tgaaacaaag ctagctgtac atatctgtac
      841 catattttta ctacaaacaa aaaatattta taattattaa ggataagata aaaaccccca
      901 acgccagatt aattcttaat aatttcaaat aaaaaatatt tgagattttt tcttttccaa
      961 ataatatatt gaaatattta aagttaaggt agcttgattt aagtagaaaa tcaaaaaaac
     1021 cattaattaa tttttcttct ttaaatattt tatatgatat tataaaatta aataacattg
     1081 cgaaaacata tgaaatcatc aaaataccaa atatatagtg ggaatgcatt attatttagc
     1141 tccttctttt ggctctgaca aattgacagt ccattgatat ccaatgcttg catttgcaat
     1201 tgctgacgca cctgcccctg ttttccctgt tagtatcaat ggttcttttc ttgcaagatg
     1261 tgcacctgca caaccaccta atactaaacc accacctatt gtaaatcctt cctgttgtat
     1321 ctctaatgat aacattttct tcttgtgccg cccttaatac agattgtgga attggattga
     1381 cctgagcagg aacttctaaa ataagttttc cttcaagctg tcttcctctt agcagattag
     1441 gtgtacttgg aacattggaa atgacaaagt gagtgcgcaa accatctgaa ggcggtgtgt
     1501 ttgaacctgt tgaaggccgc caacaggcta agtgcgcccg ctgccgccta aaaggcagcc
     1561 cggatgcctg attatcgggt atccggggag gattaagggg atatttgggt aaaattagga
     1621 ggtatttggt acgaaaacag ccgaaatcct gtgtttgggt ttcggatgtc ggggaagggc
     1681 ttttttgcaa aggtctcaac tcatgttatt gcaaagatct catgccttgt tttgccagca
     1741 ggttgagttc ttctccggca atcagcgtgg taaagccccg ccacaacaca gatctatgta
     1801 ctgtggaagg gcttcaattt atagctttcg aaaatctttc agctttaaga cggcctaaag
     1861 ttgtaatcta taaaacagga gctcagagtt ttacggctca ctctcgcttc gcgttaccaa
     1921 ataccagctt atcggttttg aacgtatagt aatctatcca atcctgcaga tattcatacg
     1981 ggtaagacaa gtcatactgt ttcataaaat cgaagatgtc ttgatattcg tctgccggca
     2041 gcggatcgta aacagtcaaa tccctcggcg cgatttcgtg gtctatgccc aaatcgaaac
     2101 cgtgcatgga tgcgattttg gcgtaggtaa cgatttgcgg ctgcaggtag aaatcgaaat
     2161 aggacaatgt ttctttggca gccatacgcg cggttttttt atcaaaaagc ggctctaagg
     2221 cggccttcat cgcctcggca tcctgttcgg cgaaagcgag gaagaagcgg taatcgtaca
     2281 accgcttttg cagccatttg ctaggggtgg gatgcgccaa gactttctcg ctacgttgtt
     2341 tcaaccgatc aagctgctta ccctccacca tcagcagagt attgtaaatc atatgccggt
     2401 tgaggtcgta gcggtttata aaggcttctg tatcgttggc gatgttgtcg atattgcgca
     2461 ccagaaactc acgcagctgt gggctgtcgc tcatcagcat cagaaacatc ggattttgaa
     2521 tgttgagcat gtcacaggga aagaagaagg gttcagggtc tgtagaattt acactcagca
     2581 aaacccccag ctttcctgca acataagcat attgcttgaa tttcttaaga tcatgttcaa
     2641 atagataggc atgggaagct gcagctctaa cgtccatgaa aatatgttgc atagctgcaa
     2701 gcggaacgcc ttttctttca tctacataat ctatagagtc aaggcaaccg ctattgaaat
     2761 tagcagtatt gcctatgatt acattagtaa tatgctcata ccatttttgg gtggtcatca
     2821 tattgtgccc cattgttatc tccttatatt gg
//
LOCUS       DAXIDM010000160         2849 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000160 DAXIDM010000000
VERSION     DAXIDM010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2849
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.160"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(38..514)
                     /gene="greA"
                     /locus_tag="ACFOAE_001966"
     CDS             complement(38..514)
                     /gene="greA"
                     /locus_tag="ACFOAE_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003688476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0070063 - RNA polymerase binding [Evidence
                     IEA];
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFC6885374.1"
                     /translation="MQKIPLTVRGAELLKQELQQLKSVARPEVIEAIAEARSHGDLSE
                     NAEYEAAKERQGFIEGRISELEHKLSVAHIINPTEIHAEGKIVFGTTVTLEDLETEEH
                     VTYQIVGEDEADIKQGKIYVGSPIARALIGKEEGDTAEVQAPGGVREYDIIEVRYI"
     gene            909..2210
                     /gene="aroA"
                     /locus_tag="ACFOAE_001967"
     CDS             909..2210
                     /gene="aroA"
                     /locus_tag="ACFOAE_001967"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015815702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFC6885375.1"
                     /translation="MTESLRLPAASLKPSTVALPGSKSISNRTLLLAALSDNTCEIHS
                     LLKSDDTDRMLEALDKLGVEIEYLAEDRLKVHGTGGRFPNRTADLFLGNAGTAFRPLT
                     AALAVLGGDYHLHGVPRMHERPIGDLADALRIAGADVEYLGKEHYPPLHIGKRQDNGE
                     RVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGELISKPYIDITLKLMAQFGVQVIN
                     EGYRVFKIPADAHYHAPEHLHVEGDASSASYFLAAGLIAATPVRVTGIGANSIQGDVA
                     FACELEKIGADVVWGENFVEVSRPKERAVQAFDLDANHIPDAAMTLAVVALATGQTCT
                     LRNIGSWRVKETDRIAAMANELRKLGAKVAEEAEAIHITPPETPTPDAVIDTYDDHRM
                     AMCFSLVSLLDVPVVINDPKCTHKTFPTYFDVFSSLTETAE"
     gene            complement(2253..2786)
                     /locus_tag="ACFOAE_001968"
     CDS             complement(2253..2786)
                     /locus_tag="ACFOAE_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFC6885376.1"
                     /translation="MFPPDKTLFLCLSALLLASCGTTSGKHRQPKPKQTVRQIQAVRI
                     SHIDRTQGSQELMLHSLGLIGTPYKWGGSSTATGFDCSGMIQFVYKNALNVKLPRTAR
                     DMAAASRKIPDSRLKAGDLVFFNTGGAHRYSHVGLYIGNGEFIHAPSSGKTIKTEKLS
                     TPFYAKNYLGAHTFFTE"
BASE COUNT          599 a          784 c          772 g          694 t
ORIGIN      
        1 ttcctgcgtg tgtcgggtgt atcgaaatca agccgaatca aatatatcgg acttcgataa
       61 tgtcgtattc gcgcacgccg cccggggctt ggacttccgc cgtatccccc tcttccttgc
      121 cgattaaggc gcgggcgatg ggtgagccga catagatttt gccctgtttg atgtcggctt
      181 cgtcttcgcc gacaatttgg taggtaacgt gttcttccgt ttccaaatct tccagcgtaa
      241 ccgtcgtacc gaacacgatt ttgccttcgg cgtggatttc ggtcggattg atgatgtggg
      301 caacggaaag tttgtgttcc agctcggaaa tgcggccttc gataaagcct tggcgttctt
      361 tggcggcttc atattcggcg ttttcggaca aatcgccgtg cgatctggct tcagcaatcg
      421 cttcgatcac ttcggggcgc gccacgcttt taagctgctg caattcctgt ttcagcaatt
      481 ccgcaccgcg tacggtcagg gggatttttt gcatcggtct tttttctcca tattccggca
      541 caccgttttg cggcagcaag cataccgcgt accgtcttgt tttgtgcgtc cggatattaa
      601 aataaaaata caagccgccc ggaaaatcgg cggcttgtct gtcgttgaac agcggctatt
      661 ctaccaaatt ctatgaaatt ggcaatcgta ccgtaccgtc cgcaaacgcc acctgcccgc
      721 aacaaaagcc gaaaatatgc cggcaaaaaa attttagaaa caaaaaattt aaaaataatc
      781 aattttcggc ataaaaaacc acattcacgg actttaaaac cgaaaatgcc aaacctgaga
      841 tttttcatac agcatttgca ccagtataat gcaggctgtt tttatcttta taatattgac
      901 gttttgccat gaccgaatcc ctccgcctcc ctgccgcctc gctcaaacct tccaccgtcg
      961 ccctgcccgg ctccaaaagc atcagcaacc gcaccctgct gctcgccgcc ttgtccgaca
     1021 atacttgtga aatccattcc ctgctcaaat ccgacgatac cgaccgtatg ctcgaagcac
     1081 tcgataaact cggcgttgaa atcgaatatc ttgccgaaga ccgtctgaaa gtgcacggca
     1141 caggcggacg cttccccaac cgcactgccg atttgttttt gggcaacgcg ggcacggcgt
     1201 tccgtccgct gactgccgca cttgccgttt tgggcggcga ttatcatctg cacggcgtgc
     1261 ctcgtatgca cgaacgcccc atcggcgatt tggccgatgc gctgcggatt gccggcgccg
     1321 atgtcgaata tctcggcaag gaacactatc cgccgcttca tatcggcaaa cgtcaagaca
     1381 acggcgaacg cgtgattccg attaaaggca atgtgtccag ccagtttctg accgcccttt
     1441 taatggcgtt gccgctgacc gggcaggcgt ttgaaatccg tatggtcggc gagttaattt
     1501 ccaagcccta tatcgacatt actttaaaac tgatggcgca attcggcgta caggttatca
     1561 atgaaggcta ccgcgtcttc aaaattcccg ccgatgcgca ctaccacgcg cccgaacact
     1621 tgcacgtcga aggcgatgcc tccagcgcgt cctacttcct cgcagccggt ttgattgccg
     1681 ccacgcccgt ccgcgttacc ggtatcggcg caaacagcat acagggcgat gtcgcctttg
     1741 cctgcgagct ggaaaaaatc ggtgcggacg tggtttgggg cgaaaacttc gtcgaagtct
     1801 cgcgcccgaa agaacgtgcc gtccaagcct ttgatttgga tgcaaaccat atccccgatg
     1861 ccgccatgac cctcgccgtc gtcgcgcttg ctacagggca aacctgcacg cttcgcaaca
     1921 tcggttcgtg gcgcgtcaaa gagaccgacc gcattgccgc aatggcgaac gagttgcgca
     1981 aactcggtgc aaaagtcgcc gaagaagccg aagcaattca catcaccccg cccgaaacgc
     2041 cgacacccga cgccgtcatc gacacttacg acgaccaccg catggcaatg tgtttctcgc
     2101 tggtttcgct gttggacgta cccgtcgtca tcaacgatcc gaaatgcacc cacaaaacct
     2161 tcccgactta tttcgacgtg ttctcatcgc tgaccgaaac agcggaataa ggcggcattt
     2221 tgccgcgatt ccggcgcggc gcggcgggcg gctcattctg taaagaaagt atgtgcgccg
     2281 aggtagtttt tggcgtaaaa cggtgtggag agtttttcgg ttttgatggt tttgccgctg
     2341 ctgggggcat ggatgaattc gccgttgccg atatagagtc cgacgtgtga gtagcggtgt
     2401 gcgccgccgg tgttgaagaa tacgaggtcg ccggccttaa ggcggctgtc ggggattttg
     2461 cggcttgccg ccgccatgtc gcgggcggtg cgcggcagct tgacgttgag ggcgtttttg
     2521 taaacgaatt gaatcatgcc gctgcaatcg aagccggttg cggtgctgct gccgccccat
     2581 ttgtagggcg tgccgatgag tccgaggctg tggagcatga gttcctgcga gccttgtgtg
     2641 cggtcgatgt ggctgatgcg gacggcttgg atttgccgga ctgtctgttt gggtttcggt
     2701 tggcggtgtt tgccggaggt cgtgccgcat gaggcgagga gcagtgcgct gagacagagg
     2761 aaaagggttt tgtcgggggg aaacatggtt tttcctttgc gggttcggat atgccgtctg
     2821 aaggtgtttc agacggtata gtggattaa
//
LOCUS       DAXIDM010000161         2833 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000161 DAXIDM010000000
VERSION     DAXIDM010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.161"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(201..488)
                     /locus_tag="ACFOAE_001969"
     CDS             complement(201..488)
                     /locus_tag="ACFOAE_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002217501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885377.1"
                     /translation="MDDLIAAFLGYLSGKYREGKISRLELSLTAGSIFFAVFFIHELI
                     IFIVDGNKENLWNFITGIMKDLFLFSCFVCLLFYFLLFIAETIGKTINKIK"
     gene            complement(795..1226)
                     /locus_tag="ACFOAE_001970"
     CDS             complement(795..1226)
                     /locus_tag="ACFOAE_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019742834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885378.1"
                     /translation="MMFFQIACNSENSYISLLKSMRFYIDNKECDYIFFRKAVNISDD
                     FIQSGFITPEGLITKNSNPKLFNQYSKMVSKNKCQYEMVTFLSDEMKNIIELLSNDDA
                     YIEFSYSEDFYVLPEIEIDKRTLKSLNFYIDFGVKYIINKI"
     gene            complement(1300..1743)
                     /locus_tag="ACFOAE_001971"
     CDS             complement(1300..1743)
                     /locus_tag="ACFOAE_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002232275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885379.1"
                     /translation="MKKQITAAVMMLSMIAPAMANGLDNQAFEDQVFHTRADAPMQLA
                     ELSQKEMKETEGAAAPLVAIGILHAGRFLAQRWVTQRVAAQALSRGANVYARTSQQAR
                     AVANQAWGRQNVIRHGQKEIHSNYSHFQNSSQKIRGHAFYGNKHR"
     gene            complement(1906..2178)
                     /locus_tag="ACFOAE_001972"
     CDS             complement(1906..2178)
                     /locus_tag="ACFOAE_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885380.1"
                     /translation="MFAVIFFSTLGCILAWIRDIPKIKSKKILARSLYIIGIINVIIS
                     YVLIKNILVSVSDGGGIKYVAIYLSNLFFWTVLMYVLVKRLSKKPS"
BASE COUNT          961 a          549 c          390 g          933 t
ORIGIN      
        1 tccactatac aaaacaatca agaaactatt ggcggtatgt ataatcttga attttgtttt
       61 ttgatgaaat taaaataatg aaatatatgg taaacgttac aacggaagcc ttagcctccc
      121 gattgcagta tttcaattcc aagataaatg ccgcatagaa aagataaaat acttaaatgg
      181 tttttagcgg cttaaatatc ttatttaatc ttattgattg tttttccaat ggtttccgca
      241 ataaataata agaagtagaa taataaacaa acaaaacatg aaaataaaaa taaatctttc
      301 attatcccag taataaaatt ccaaagattt tccttatttc catcaacaat aaaaattatc
      361 agttcatgaa taaagaatac tgcaaagaaa atacttcctg ccgttaggga tagttctaac
      421 ctgcttattt tcccttctct atatttacct gataaatagc ctaaaaaagc tgcaatcaaa
      481 tcatccattt taaaaatttc tgtaaaaaca ggtaatgtct ttaattcatt acctgttttg
      541 ccattattta tagtggatta aatttaaatc aggacaaggc gacgaagccg cagacagtac
      601 aaatagtacg gcaaggcgag gcaacgccgt actaatccac tatatatatc cattcatata
      661 gagaaaaatt cttataccca atataaaaca aggtctttca ttatattttg aaaaacctag
      721 aagctttgta tctattggtt tatcaaaatt aataattatt gcagaagaca tgtaggctaa
      781 taatcttgat ttatctatat tttattaatt atatatttaa ccccgaagtc aatatagaaa
      841 tttagtgatt ttaaagttct cttatcaatt tcaatctcag ggagtacata aaaatcctca
      901 gaataggaaa actctatata tgcatcatca ttcgataata attcaataat atttttcatt
      961 tcatcagaaa gaaatgtaac catctcatat tgacatttat ttttagatac catttttgaa
     1021 tattgattaa ataattttgg attactattt ttagtaatta atccttccgg agtaataaaa
     1081 ccactttgta taaagtcatc acttatatta acagccttcc gaaaaaaaat ataatcacac
     1141 tctttgttat caatataaaa tctcatactc tttaataatg aaatataaga attttcagaa
     1201 ttacaagcaa tttgaaaaaa catcattact cctaaaactc ataaatagta aggaatatat
     1261 atatatgcat attccttact attttttcac aaattatgct tatctatgct tatttccata
     1321 aaaagcatgc cctcgaattt tttgacttga gttctggaaa tgagaataat ttgaatggat
     1381 ttccttctgt ccatgtctaa taacattttg tcttccccaa gcttggtttg ctaccgctct
     1441 tgcttgttga gatgttcgtg catagacatt agctcctctt gataaagctt gtgctgcaac
     1501 acgctgcgta acccaacgct gcgcaaggaa tctgcccgca tgcaaaattc ctattgccac
     1561 caacggtgcc gcagcccctt cagtttcttt catctccttt tgagaaagct ccgccaactg
     1621 catcggcgca tctgcccgcg tgtggaacac ttggtcttca aatgcctgat tgtccaagcc
     1681 gtttgccatt gcgggggcaa tcatagacag catcattacg gctgcggtga tttgtttttt
     1741 cataataact cctttggatt acaaggttgg aaaatcaaag ccctgcttag aacgtatgtt
     1801 gcacacccaa tttcaatagg taaatcagat tgcaaatcca gcaatttgaa tattgtcatt
     1861 gttccgtgca aaagggattt ttattgatga gttgtgtact gggtttcagc ttggtttttt
     1921 agataatctt ttcacaagaa catacatcaa tactgtccaa aaaaaaagat ttgataaata
     1981 tattgcaaca tattttattc cacctccatc cgaaacagaa accaatatat ttttaattaa
     2041 tacatagctg attattacat ttattattcc tataatatat aaggatcttg ccaaaatttt
     2101 ttttgatttt attttaggaa tatctcttat ccatgctaaa atacagccca atgtcgaaaa
     2161 gaaaataaca gcaaacacta ccttacctcc tctcacttcc aaccaaaccg atagcaggtt
     2221 tggttggaag ttggtttatt tattatttaa cggcgaatgt cagtgttctt acccgtagaa
     2281 cctgcataac catttatgcc accagcaaca gcccccactg ctacacctcg cataccatta
     2341 atcagaattc ttcctatttt ttcgaatcca ctatttcttc caaagatgca gcaaacgcag
     2401 gttgagccta gacccaatct acgtttgctg ccgcatctga tccctattgt ttcttatcct
     2461 tacatcttcc tgccttgtca atcaaataaa gacagaagac tatacaaaaa ctgaccgaca
     2521 tactgaaaat acctatcccc ttccatgcaa tctccgcacc attgacccaa tagattagac
     2581 tgagaaacaa caaagccaca gtataaatca acgtaaaaaa tattgcgtaa agcacaataa
     2641 agggaacttt tatctcacgg ttgtttttta taatatattc agcaacttga tttccgaata
     2701 tacctgataa aaaatatagt attagatcat ccatttcgtt tatcttctat gttttcccat
     2761 tgcggcgcta gaagactgat ttaatgctgc accatgcaat atagtgaatt aacaaaaacc
     2821 agtacggcgt tgc
//
LOCUS       DAXIDM010000162         2792 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000162 DAXIDM010000000
VERSION     DAXIDM010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2792
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.162"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(1..563)
                     /locus_tag="ACFOAE_001973"
                     /pseudo
     CDS             complement(1..563)
                     /locus_tag="ACFOAE_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(1189..2346)
                     /locus_tag="ACFOAE_001974"
     CDS             complement(1189..2346)
                     /locus_tag="ACFOAE_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HFC6885381.1"
                     /translation="MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNIQLQLTEPL
                     PNIQPQVTKRKSRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGASQWG
                     NRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMSVSVR
                     YDSPEFSGFSGSVQFVPAQNSKSAYTPAHFVQNKQNQPPTLVPAVVGKPGSDVYYAGL
                     NYKNGGFAGNYAFKYAKHANVGRDAFELFLLGSGSDEAKGTDPLKNHQVHRLTGGYEE
                     GGLNLALAAQLDLSENGDKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGE
                     NTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF"
BASE COUNT          678 a          696 c          672 g          746 t
ORIGIN      
        1 ccgaagctct gttcgaccac ataacgggtc ttcgacaaat atcggttgcg tttggtttgc
       61 gtttccgtca gcggacggtt gcggcaggct ttgcgcataa tgccgtccgg taactgatgt
      121 tctttcagat gttgccggtt ttccgcactg tcatagcctt tgtcggcata gacggtcgta
      181 ccttcggcta tcccttccag caaaggcgac aggtgtttgc actcatgggc attggcgggg
      241 gtgatgtgca gtttctcgat atagccttcc gcatcggtac gggtatgttg tttgtaaccg
      301 agtttgtaga ggccgttttt ctttatccaa cgggcatcgc tgtccttact cggtgtggtt
      361 tggccgctga cttgtccttc ttcgtcaact tctatggcct gacgctgttt gctgccggcg
      421 gtctgaataa tggtggcgtc aacgacggcg gcggatgctt tctctatttt taagcctttt
      481 tcggtcagtt ggcggttaat cagttccagc aattcggaca gggtgtcgtc ttgcgccagc
      541 cagttgcggt aacggcataa agtatagtgg attaacaaaa atcaggacaa ggcgacgaag
      601 ccgcagacag tacaaatagt acggaaccga ttcacttggt gcttcagcac cttagagaat
      661 cgttctcttt gagctaaggc gaggcaacgc cgtactggtt tttgttaatc cactatactg
      721 taatcgggga tgctcagttc gtcaaagcgg caacacaggt tgagtggtat ggccggagta
      781 ttgattaaat ccattttaaa aacctcttaa aacagtttta aaaattccct aatctcgtca
      841 gctttaaaca gaaaaccgcg cattccggcg cggtttcgtg aaaaagctgg cgtaactttt
      901 ccggatgcaa aaaacgccga aatccacgtc ttccgaagat ttcagcgttt ttttactcta
      961 tttgttcctt gtgcaaaaac taacagtccc ccacaatatg tgcaaaccaa gccgaaaatg
     1021 cgaaataccg tctgaaaatc tttcagacgg tatttgctgt ctttattgcc gtttttcttc
     1081 cgtatccgga tttttgtttg gggctgaagc agattggcag tcagattgca atcaaagaat
     1141 gaaggcaagc cgtcaaaaac aaagctatcc gcttcaccgc cccgatattt agaatttgtg
     1201 gcgcaaaccg acggaggcgg cattaatttg agtgtagttg ccgatgccgg tattgcgttt
     1261 cagccaagcg ccagacacga tggcggaagt gcgtttggaa aaatcataat caacgccggc
     1321 gatgatttga tcgtagctgg tattttcgcc ttttttaccg cgttcgataa agtcgaaacc
     1381 atgggcatag ctgatgcgcg ggactgcatt accgaagcgg taggaagcag tggcggcaat
     1441 ttcggtcgta ctgtttttgg ttttgtcgcc attttcagac aaatccaact gagccgccaa
     1501 ggcgagattc aagccgcctt cctcatagcc gcccgtcagg cggtgtacct gatggttttt
     1561 caagggatcg gtacctttgg cttcatcact cccgctgccg agcaagaaca actcaaaagc
     1621 atcacggccc acattggcgt gtttcgcgta tttaaaggca tagttcccgg caaaaccgcc
     1681 atttttgtaa ttcagaccgg cataatacac atccgacccc ggcttgccga caacagccgg
     1741 aacgagagta ggcggctgat tttgcttatt ctgaacaaaa tgagccggcg tataggcgga
     1801 cttgctgttt tgggccggaa cgaattggac gctgccgcta aaaccggaaa actcggggga
     1861 atcgtagcgt acggaaaccg acatatcgtc gtggcgtttg aaaataccca attgcgaagc
     1921 cacatcatta ttgctgtccc aaggatcaat ggcttggctg gcatcgtcaa actgatttgc
     1981 aacgcgaccg gcgcgcagcg tgccgaattc gcctgccaag ccgataaagg attccctgtt
     2041 gccccactgg gacgcgccgc cgccggcaac ggatacgtct tgctcaagct gccaaacagc
     2101 cttcagccct tcgcccaaat cctcactccc cttaaagccg ataaacgagc cgaaatcgct
     2161 gattttcgtc ctgatgcggc ttttgcgctt agtaacctga ggttgaatat ttgggagcgg
     2221 ttcggtcaac tgcagctgga tgttcctgcc ttccacgccg gctttgattt cgccgtacag
     2281 gctaacatcg gcaacggccg caagcggcag tgcggacaat acgagcgcgg taagtttttt
     2341 tcgcatatcg gcttcctttt gtaaatttga taaaacctaa aaacatcggg caaacacccg
     2401 atatgtcatc aattataccc ccccccccgc aaaaaaccat ttttcagaac aaatatctga
     2461 taaatgccgc aacctttatt ttaaaaatga ttatattttg atataaaaca atagcttatt
     2521 ttttcaaaaa acgttgtgtt tctacaacac aattcaagcg cagacctcgt gcgggccgat
     2581 gcgctgctac ccggatgcag tcccagcttt ttaaaacgcc ataaaaaaac acacgcggca
     2641 ctttatagtg gattaacaaa aaccagtacg gcgttgcctc gccttagctc aaagagaacg
     2701 attctctaag gtgctgaagc accaagtgaa tcggttccgt gctatttgta ctgtcttcgg
     2761 cttcgccgcc ttgtcctgat ttttgttaat cc
//
LOCUS       DAXIDM010000163         2653 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000163 DAXIDM010000000
VERSION     DAXIDM010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2653
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.163"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            313..2487
                     /gene="fetA"
                     /locus_tag="ACFOAE_001975"
                     /gene_synonym="frpB"
     CDS             313..2487
                     /gene="fetA"
                     /locus_tag="ACFOAE_001975"
                     /gene_synonym="frpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021438799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor FetA/FrpB"
                     /protein_id="HFC6885382.1"
                     /translation="MNAPFFRLSLLSLTLAAGFAHAAENNANVALDTVTVKGDRQGSK
                     IRTNIVTLQQKDESTATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNA
                     YSDSQILYHQGRFIVDPALVKVVSVQKGAGSASAGIGATNGAIITKTVDAQDLLKGLD
                     KNWGVRLNSGFASNEGVSYGASVFGKEGNFDGLFSYNRNNEKDYEAGKGFRNNFNGGK
                     TVPYSALDKRSYLAKIGTSFGDGDHRIVLSHMKDQHRGIRTVREEFTVGGDKERISME
                     RQAPAYRETTQSNTNLAYTGKNLGFVEKLDANAYVLEKKRYSADDKGSGYAGNVVGPN
                     HTRITTRGMNFNFDSRLAEQTLLKYGINYRHQEIKPQAFLNSKFKISDKKPDPNNPGK
                     EIAKTDEEKAKDKIDMALVHSYKLSNPTKTDTGAYIEAIHEIDGFTLTGGLRYDRFKV
                     KTHDGKTVSSSNLNPSFGVIWQPHEHWSFSASHNYASRSPRLYDALQTHGKRGIISIA
                     DGTKAERARNTEIGFNYNDGTFAANGSYFWQTIKDALANPQNRHVSAAVREAVNAGYI
                     KNHGYELGASYRTGGLTAKVGVSHSKPRFYDTHPKKLLSANPEFGAQTGRTWTASLAY
                     RFQNPNLEIGWRGRYVQKAVGSILVAGQKDRNGKLENVVRKGFGVNDVFANWKPLGKD
                     TLNVNLSVNNVFNTFYYPHSQRWTNTLPGVGRDVRLGVNYKF"
BASE COUNT          758 a          756 c          594 g          545 t
ORIGIN      
        1 tttgttaatc cactatattt ccgccgtttt ttatagtgga ctaacaaaaa ccagtacagc
       61 gttgcctcgc cttgccgtac tatctgtact gtctgcggct tcgtcgcctt atcctgattt
      121 ttgttagtcc actatacatt tccgacaaaa cctgtcaaca aaaaacaaca cttcgcaaat
      181 aaaaacgata atcagcttta cacaaatccc ccctctcgtt aatataaaca aaaataatta
      241 ttatttttct tatcctgcca aaccttaacg gtttggattt acttcccttc atacactcaa
      301 aaggacgaac aaatgaacgc cccgtttttc cgcctcagcc tgctctcgct taccctggcg
      361 gcaggttttg cccatgcggc agaaaataat gccaatgtcg cattggatac cgttaccgta
      421 aaaggcgacc gccaaggcag caaaatccgt accaacatcg ttacgcttca acaaaaagac
      481 gaaagcaccg caaccgatat gcgcgaactc ttaaaagaag agccctccat cgatttcggc
      541 ggcggcaacg gcacgtccca attcctgacg ctgcgcggta tgggtcagaa ctctgtcgac
      601 atcaaggtgg acaacgccta ttccgacagc caaatccttt accaccaagg cagatttatt
      661 gtcgatcccg ctttggttaa agtcgtttcc gtacaaaaag gcgcgggttc cgcctctgcc
      721 ggtatcggcg cgaccaacgg cgcgatcatc accaaaaccg tcgatgccca agacctgctc
      781 aaaggcttgg ataaaaactg gggcgtgcgc ctcaacagcg gctttgccag caacgaaggc
      841 gtaagctacg gcgcaagcgt attcgggaaa gagggcaact tcgacggctt gttctcttac
      901 aaccgcaaca atgaaaaaga ttacgaagca ggtaaaggct tccgtaataa tttcaacggc
      961 ggcaaaaccg taccgtacag cgcgctggac aaacgcagct acctcgccaa aatcggaaca
     1021 agcttcggcg acggcgacca ccgcatcgta ttgagccata tgaaagacca gcaccggggc
     1081 atccgtaccg tccgtgaaga atttaccgtc ggcggcgata aagagcgaat aagtatggaa
     1141 cgccaagccc ctgcttaccg cgaaaccaca caatccaaca ccaatttggc gtacacgggt
     1201 aaaaacctgg gctttgtcga aaaactggat gccaacgcct atgtgttgga aaagaaacgc
     1261 tattccgccg atgacaaagg cagcggctac gcaggcaatg tggtcggccc taaccatacc
     1321 cgaatcacca ctcggggtat gaatttcaac ttcgacagcc gccttgccga acaaaccctg
     1381 ttgaaatacg gtatcaacta ccgccatcag gaaatcaaac cgcaagcgtt tttgaacagc
     1441 aaatttaaga tctccgataa gaaaccagac ccaaacaatc ccggaaaaga aatagctaag
     1501 accgatgaag aaaaagcgaa agacaagata gatatggctc ttgtccattc ctacaaactt
     1561 tccaacccga ccaaaaccga taccggcgcg tatatcgaag ccattcacga gattgacggt
     1621 tttaccctga ccggcgggct gcgttacgac cgcttcaagg tgaaaaccca tgacggcaaa
     1681 accgtttcaa gcagcaacct taacccgagt ttcggcgtga tttggcagcc gcacgaacac
     1741 tggagcttca gcgcgagcca caactacgcc agccgcagcc cgcgcctgta tgacgcgctg
     1801 caaacccacg gtaaacgcgg tatcatctcg attgccgacg gcacgaaagc cgaacgcgcg
     1861 cgcaataccg aaatcggctt caactacaac gacggcacgt ttgccgccaa cggcagctac
     1921 ttctggcaaa ccatcaaaga cgcgcttgcc aatccgcaaa accgccacgt ctctgccgcc
     1981 gtccgtgaag ccgtcaatgc cggttacatc aaaaaccacg gttacgaatt gggcgcgtcc
     2041 taccgcaccg gcggcctgac tgccaaagtc ggcgtaagcc acagcaaacc gcgcttttac
     2101 gatacccatc ctaaaaaact gttgagcgcg aaccctgaat ttggcgcaca aaccggccgc
     2161 acttggacgg cttcccttgc ctaccgcttc caaaatccga atctggaaat cggctggcgc
     2221 ggccgttatg ttcaaaaagc cgtgggttcg atattggtgg caggtcaaaa agaccgcaac
     2281 ggcaaattgg aaaacgttgt acgcaaaggt ttcggtgtga acgatgtctt cgccaactgg
     2341 aaaccgctgg gcaaagacac gctcaatgtt aatctttcgg ttaacaacgt gttcaacacg
     2401 ttctactatc cgcacagcca acgctggacc aataccctgc cgggcgtggg acgtgatgta
     2461 cgcttgggcg tgaactacaa gttctaaaac gcacatcccg aaaaaatgcc gtctgaaagc
     2521 ctttcagacg gcatctgttc tgataatttg atatatagtg gattaacaaa aaccagtacg
     2581 gcgttgcctc gccttagctc aaagagaacg attctctaag gtgctgaagc accaagtgaa
     2641 tcggttccgt act
//
LOCUS       DAXIDM010000164         2637 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000164 DAXIDM010000000
VERSION     DAXIDM010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.164"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            101..730
                     /locus_tag="ACFOAE_001976"
     CDS             101..730
                     /locus_tag="ACFOAE_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFC6885383.1"
                     /translation="MIQNVVTSIILYSGTAVDLLIILMLFFAKRKSRKDIINIYLGQF
                     LGSVSLILLSLLFAFVLDYIPSKEILGLLGLIPIFLGIKVLLLGDSDGEAIAKEGLRK
                     DNKNLIFLVAMITFASCGADNIGVFVPYFTTLNLANLIVALLTFLVMIYLLVFSAQKL
                     AQVPSVGETLEKYSRWFVAVVYLGLGVYILIENNSFDMLWTVSGQEKIL"
     gene            876..2534
                     /locus_tag="ACFOAE_001977"
     CDS             876..2534
                     /locus_tag="ACFOAE_001977"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArnT family glycosyltransferase"
                     /protein_id="HFC6885384.1"
                     /translation="MLTYTPPDARPPAKTHEKPWLLLLMAFAWLWPGVFSHDLWNPAE
                     PAVYTAVEALAGSPTPLVAHLFGQTDFGIPPVYLWVAAAFKHLLSPWAADPYDAARFA
                     GVFFAVVGLTSCGFAGFNFLGRHHGRSVVLILIGCIGLIPVAHFLNPTAAAFAAAGLV
                     LHGYSLARRRVIAASFLLGTGWTLMSLAAAYPAAFALMLPLPVLMFFRPWQSRRLMLT
                     AVASLAFALPLMTVYPLLLAKTQPALFAQWLDDHVFGTFGGVRHVQTAFSLFYYLKNL
                     LWFALPALPLAVWTVCRTRLFSTDWGILGIVWMLAVLVLLAVNPQRFQDNLVWLLPPL
                     ALFGAAQLDSLRRGAAAFVNWFGIMAFGLFAVFLWTGFFAMNYGWPAKLAERAAYFSP
                     YYVPDIDPIPMAVAVLFTPLWLWAITRKNIRGRQAVTNWAAGVTLTWALLMTLFLPWL
                     DAAKSHAPVVRSMEASLSPELKRELSDGIECIDIGGDLHTRIVWTQYGTLPHRVGDVQ
                     CRYRIVLLPQNADAPQGWQTVWQGARPRNKDSKFALIRKIGENI"
BASE COUNT          527 a          661 c          679 g          770 t
ORIGIN      
        1 ggtttttgtt aatccactat attttgatgg ggttgaagtt gacatctaca aagtttaatg
       61 tttgaataca ttaaaaaaat atatttgaat gagatgtttt atgattcaaa atgttgttac
      121 ttcaataatc ctgtattctg ggacagccgt agacttactt attatcctaa tgttattttt
      181 tgccaaaaga aaaagcagaa aagacatcat taacatctat ttaggacaat ttctaggctc
      241 tgttagcctg atattgctaa gtttgctttt tgcatttgtc ttagattata ttcctagtaa
      301 agagatttta ggtttgctcg gcttgattcc aattttccta ggcatcaaag ttttgctgtt
      361 aggagattct gatggagagg ctattgccaa agagggtttg cgcaaagata ataaaaacct
      421 gatttttcta gtcgctatga ttacttttgc aagttgtggt gctgacaata ttggtgtctt
      481 tgttccatat tttactacct taaatttagc gaatttgata gtggctttac ttacctttct
      541 agtcatgatt tatctcttgg ttttttctgc ccaaaaatta gcacaagtcc cttctgttgg
      601 agaaactttg gaaaaatata gcagatggtt tgttgctgtt gtttatttgg gattgggggt
      661 atatatcctg attgaaaaca acagttttga tatgctatgg actgtgtcgg gccaggaaaa
      721 aatattatga aaaagatagt atctgcaaag actgccatgt gcagtctttt ttgttgccgg
      781 tctttttgtg tctgatgccg tctgaagcag tctctgcacg acctttgtgc gaatatttgc
      841 tacacttggc aatccgtcca tttcttctca cgcttatgct gacctacact ccgcccgatg
      901 cccgcccgcc cgccaaaacc cacgaaaagc cgtggctgct gctgttgatg gcgtttgcct
      961 ggttgtggcc cggcgtgttt tcccacgatt tgtggaatcc tgccgaacct gccgtctata
     1021 ccgccgtcga agcactggca ggcagcccca cccctttggt tgcccatctg ttcggtcaaa
     1081 ccgatttcgg cataccgccc gtgtatcttt gggttgccgc cgcgttcaaa catttgctgt
     1141 cgccgtgggc agccgacccg tatgatgccg cacgctttgc cggcgtgttt ttcgccgttg
     1201 tcggactgac ttcctgcggc tttgccggtt tcaacttttt gggcagacac cacgggcgca
     1261 gcgtcgtcct gattctcatc ggctgtatcg ggctgattcc agttgcccat ttcctcaacc
     1321 ccactgccgc cgcctttgcc gccgccggac tggtgctgca cggttattct ttggctcgcc
     1381 ggcgcgtgat tgccgcctct tttctgctcg gtacgggctg gacgctgatg tcgttggcag
     1441 cagcttatcc ggcagcattt gccctgatgc tgcccttgcc cgtactgatg tttttccgtc
     1501 cgtggcaaag caggcgtttg atgttgacgg cagtcgcctc acttgccttt gccctgccgc
     1561 ttatgaccgt ttacccgctg ctcttggcaa aaacgcagcc cgcgctgttc gcgcaatggc
     1621 tcgacgatca cgttttcggt acgttcggcg gcgtgcggca cgttcagacg gcattcagtt
     1681 tgttttacta tctgaaaaac ctgctttggt ttgcattgcc tgcgctgccg ctggcggttt
     1741 ggacggtttg ccgcacgcgc ctgttttcga ccgactgggg gattttgggc attgtgtgga
     1801 tgcttgccgt tttggtgctg cttgccgtca atccgcagcg ttttcaggat aacctcgtct
     1861 ggctgcttcc gccgcttgcc ctgttcggcg cggcgcaact ggacagcctg aggcgcggcg
     1921 cggcggcgtt tgtcaactgg ttcggcatta tggcgttcgg actgtttgcc gtgttcctgt
     1981 ggacgggctt tttcgccatg aattacggct ggcccgccaa gcttgccgaa cgcgccgcct
     2041 acttcagccc gtattacgtt cccgacatcg atcccattcc gatggcggtt gccgtactgt
     2101 tcacaccctt gtggctgtgg gcgattaccc gcaaaaacat acgcggcagg caggcggtta
     2161 ccaactgggc ggcaggcgtt accctgacct gggctttgct gatgacgctg ttcctgccgt
     2221 ggctggacgc ggcgaaaagc cacgcgccgg tcgtccggag tatggaggca tcgctttccc
     2281 cggaattaaa acgggagctt tcagacggca tcgagtgtat cgacataggc ggcgacctgc
     2341 acacgcggat tgtttggacg cagtacggca cattgccgca ccgcgtcggc gatgtacaat
     2401 gccgctaccg catcgtcctc ctgccccaaa atgcggatgc gccgcaaggc tggcagacgg
     2461 tttggcaggg tgcgcgtccg cgcaacaaag acagtaagtt cgcactgata cggaaaatcg
     2521 gggaaaatat ataaaaaaca acagattgag ccgaatttct ggattaagtg ccggaaatcg
     2581 cgtataattg cgcgattaaa cctttatata gtggattaac aaaaatcagg acaaggc
//
LOCUS       DAXIDM010000165         2527 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000165 DAXIDM010000000
VERSION     DAXIDM010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2527
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.165"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(68..874)
                     /locus_tag="ACFOAE_001978"
     CDS             complement(68..874)
                     /locus_tag="ACFOAE_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HFC6885385.1"
                     /translation="MPTVFIFLTAVYAGLGAFAWHCQQQGRGRDYPWKTELPVLGAAL
                     TVHGAALLMPVIQDKIIIMGFGYSGSLIVWMMLFIYFAGSFFYPLRGVQLLLYPCAAL
                     MLLSGLVFPGKFSGYEITDLPFMLHIGTSLLAYGLFGIATLLSVLTLLLNRSLHRRSF
                     SKLAGFLPSLLSLEKLMFQAMWAGFILLTYSVVSGTFFAEAVFGKPMTFTHKTVFGIL
                     SWLIYGGLLLKHSMTAWRGKKAAVWTIIGFVSLMIAYMGSKFVLEIILNR"
     gene            1094..2464
                     /gene="ffh"
                     /locus_tag="ACFOAE_001979"
     CDS             1094..2464
                     /gene="ffh"
                     /locus_tag="ACFOAE_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFC6885386.1"
                     /translation="MLDNLTGRFSNVFKNIRGQAKLTEDNIKEALREVRLALLEADVA
                     LPVVKEFINNVKEKALGQEVAGSLTPDQAFIGVVNKALTELMGRENKTLDLSVAPPAV
                     VLMAGLQGAGKTTTVGKLARLLKNDQKKKVLVVSADVYRPAAIEQLRLLAEQVGVDFF
                     PSDTNQKPVEIATAAVDYAKKHFYDVLMVDTAGRLAIDEEMMNEIKALHAAVNPVETL
                     FVIDAMLGQDAVNTAQAFNEALPLTGVVLTKMDGDSRGGAALSVRHVTGKPIKFIGVG
                     EKINGLEPFHPDRLASRILGMGDVLTLIEDVQKGIDEEAAAKMAKKLHKGKGFDLNDF
                     KEQIQQMRNMGGLENLMSKMPGELGQISKQIPEGTAEKAMGKVEAIINSMTPKERANP
                     ALLKASRKRRIAMGAGTTVQEVNKLLKQFEQMQQMMKMFSGNGLGKLMRMAKGMRGIK
                     GMFPGL"
BASE COUNT          687 a          637 c          666 g          537 t
ORIGIN      
        1 ggctggtgcg cctttgtgaa tatgccgtct gaaactcggg gactcagacg gcatctgttg
       61 gctcttctta tctgttcaga atgatttcca atacgaactt gctgcccata taggcaatca
      121 taaggctgac aaatccgatg atggtccaca cggcggcttt tttgccgcgc catgcggtca
      181 tgctgtgctt gagcagcagt ccgccgtaaa tcagccatga caatatgccg aatacggttt
      241 tatgggtaaa ggtcatgggt ttgccgaata cggcttcggc aaaaaatgtt ccgctgacga
      301 cggaataggt cagcaggatg aaacctgccc acatggcctg gaacatgagt ttttccaaac
      361 tgagcagcga cggcaggaat cctgcgagct tggagaagct cctgcggtgc aggctgcgat
      421 tcagcagcag ggtcaaaacg gacaataatg ttgcgatgcc gaacagcccg tatgcgagca
      481 gcgaagttcc gatatgcagc ataaagggaa ggtcggtaat ttcatatccc gagaattttc
      541 caggaaaaac caaacctgac agcagcatca gtgcggcgca aggatacagc agcaactgca
      601 ctccgcgcag cggataaaag aagctgccgg caaaataaat aaacagcatc atccaaacaa
      661 tcaggctgcc ggaatacccg aagcccataa tgatgatttt gtcttgaatg accggcatca
      721 gcagtgccgc gccgtggacg gtcaatgccg cgcccaaaac cggcaattcc gtcttccacg
      781 ggtaatcccg accgcgcccc tgctgttggc agtgccatgc aaatgcaccc aatcctgcgt
      841 aaaccgccgt caaaaagatg aaaactgtcg gcatggtgga ctttctctat ctatactgtt
      901 gcgccgtctg cggccgctta tgaaatattg gaacttttaa cgttggaatt gtaaaatccc
      961 cgtttcgggc aagccttgac ggatttgccg atatgctgtc cggcacacaa gccgcatcaa
     1021 attattttga ttttatttta acaaagaatg cccctgatgg ggcaagctat tcttattcag
     1081 accaaggacc agtatgttag acaatttaac cggccgcttc agcaatgtct tcaaaaacat
     1141 ccgggggcag gccaaactga ccgaagacaa tattaaagag gccttgcgcg aagtccgcct
     1201 cgccctgctt gaggcggatg tcgccctgcc tgtcgtcaaa gagttcatca acaacgtcaa
     1261 agaaaaggcc ctcggtcagg aagtagcggg cagcctgacg ccggatcagg catttatcgg
     1321 cgtggtcaac aaagccctga ccgaactgat gggcagggaa aacaaaacgc tggatttgtc
     1381 ggttgcgccg cccgccgtcg tgttgatggc aggtttgcag ggcgcaggca agacgacgac
     1441 cgtcggcaaa ctcgcccgcc tgttgaaaaa cgatcagaag aaaaaggttt tggtggtatc
     1501 cgccgacgtt taccgtcctg ccgcgattga acagctgcgt ctgttggccg aacaggtcgg
     1561 cgtggatttt ttcccgtccg ataccaacca aaaaccggtt gaaattgcaa ctgccgccgt
     1621 cgattacgcc aaaaaacatt tttacgatgt attgatggtc gataccgccg gccgtttggc
     1681 aatcgatgaa gagatgatga acgaaatcaa agcccttcac gcggcggtta acccggtgga
     1741 aactttgttc gtcatcgatg cgatgctggg tcaggatgcg gtgaacactg ctcaggcatt
     1801 taatgaagcc ctgccgctga ccggtgtcgt attgaccaag atggacggcg attcgcgcgg
     1861 cggcgcagct ttgtccgtgc gccacgtaac cggcaaaccg attaaattta tcggtgtcgg
     1921 cgaaaaaatc aacggcctcg aacctttcca ccccgaccgt cttgccagcc gtatcctcgg
     1981 catgggcgac gtattgaccc tgattgaaga cgttcaaaaa ggtattgatg aagaagccgc
     2041 cgccaaaatg gcgaaaaagc tgcacaaagg caaaggcttc gacctcaacg actttaaaga
     2101 acaaatccag caaatgcgca atatgggcgg tttggaaaac ctgatgtcga aaatgccggg
     2161 cgaactgggt caaatctcga aacaaatccc cgaaggaacg gctgaaaaag cgatgggcaa
     2221 agtagaagcc atcatcaact cgatgacccc taaagaacgc gccaaccctg ccctgctcaa
     2281 agccagccgc aaacgccgta ttgcaatggg tgcgggcaca accgtgcagg aagtgaacaa
     2341 attgctcaaa cagtttgaac aaatgcaaca gatgatgaag atgttcagcg gcaacggctt
     2401 gggcaaactg atgcgtatgg cgaaaggaat gagggggata aaagggatgt tcccgggttt
     2461 gtaagccgat ttaacagaaa acgccgtctg aaaagtttca gacggcgttt ttgttttata
     2521 ttctgat
//
LOCUS       DAXIDM010000166         2497 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000166 DAXIDM010000000
VERSION     DAXIDM010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2497
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.166"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            168..791
                     /gene="lolA"
                     /locus_tag="ACFOAE_001980"
     CDS             168..791
                     /gene="lolA"
                     /locus_tag="ACFOAE_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0042597 - periplasmic space [Evidence
                     IEA];
                     GO_process: GO:0042953 - lipoprotein transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HFC6885387.1"
                     /translation="MMKPHNLFQFLAVCSLTVSVASAQAGAVDALKQFNNDADGISGS
                     FTQTVQSKKKTQTAHGTFKILRPGLFKWEYTSPYKQTIVGDGQTVWLYDVDLAQVTKS
                     SQDQAIGGSPAAILSNKTALESSYTLKEDGSSNGIDYVLATPKRNNAGYQYIRIGFKG
                     GNLAAMQLKDSFGNQTSISFGGLNTNPQLSRGAFKFTPPKGVDVLSN"
     gene            1064..2203
                     /locus_tag="ACFOAE_001981"
     CDS             1064..2203
                     /locus_tag="ACFOAE_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003709746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0019808 - polyamine binding [Evidence
                     IEA];
                     GO_process: GO:0015846 - polyamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine ABC transporter substrate-binding
                     protein"
                     /protein_id="HFC6885388.1"
                     /translation="MKKTLVAAAILSLALTACGGGSDTAAHPPSAKPEAEQSGKLNIY
                     NWSDYVDPETVAAFEKETGIKTRSDYYDSNETLEAKVLTGKSSYDLTAPSIANVGRQI
                     KAGAYQKIDKAQIPHYGNIDKDLLKMMEAVDPGNEYAVPYFWGINTLAINTRQVQKAL
                     GTDKLPENEWDLVFNPEYTAKLKSCGISYFDSAIEQIPLALHYLGKDPNSENPEDIKA
                     AVDMMKAVRGDVKRFSSSGYIDDMAAGNLCAAIGYGGDLNIAKTRAEEAANGVEIKVL
                     TPKTGVGVWVDSFMIPRDAQNVANAHRYIDYTLRPEVAAKNGSFVTYAPASRPARELM
                     DEKYTSDASIFPNKELMEKSFIVSPKSAESAKLGVKLWQGLKAGK"
     gene            2336..>2497
                     /locus_tag="ACFOAE_001982"
     CDS             2336..>2497
                     /locus_tag="ACFOAE_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003704837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFC6885389.1"
                     /translation="MDLSIVVPIYNVESYLEACLNSIEPILSNENVELILVNDGSKDG
                     SEDICYKYID"
BASE COUNT          673 a          741 c          619 g          464 t
ORIGIN      
        1 gcggcacaca attaaagggc agcgtggcgc gccgcctttt ccggtgggca aaaaatcagc
       61 cctcggaaaa cgcggtttgc aaaatgcaaa ccgcccgtaa cgccgcccat atgattgttt
      121 tgccgcgccg atactttacg ccacactcat tccaacaagg aaaaataatg atgaaaccgc
      181 acaacctgtt ccaattcctc gccgtttgct ccctgaccgt ctccgtcgct tccgcacagg
      241 cgggcgcggt ggacgcgctc aagcaattca acaacgatgc cgacggtatc agcggcagct
      301 tcacccaaac cgtccaaagc aaaaagaaaa cccaaaccgc gcacggcacg ttcaaaatcc
      361 tgcgcccggg cctcttcaaa tgggaataca cttcgcccta caaacagact attgtcggcg
      421 acggtcaaac cgtttggctc tacgatgtcg atttggcaca agtgaccaag tcgtcccaag
      481 accaggccat aggcggcagc cccgccgcca tcctgtcgaa caaaaccgcc ctcgaaagca
      541 gctacacgct gaaagaggac ggttcgtcca acggcatcga ttatgtgctg gcaacgccca
      601 aacgcaacaa cgccggctac caatacatcc gcatcggctt caaaggcggc aacctcgccg
      661 ccatgcagtt gaaagacagc ttcggcaacc aaacctccat cagtttcggc ggtttgaata
      721 ccaatcccca actctcgcgc ggcgcgttca agtttacccc gcccaaaggc gtggacgtgt
      781 tgagcaactg atgccgtccg ccccgatgcc gtctgaacgc cgccgaggct tcagacggca
      841 tttttacgca ggcggaacaa tgtcccgcat taccgcccga tcgggcaccg gaacggcaaa
      901 ccgatgaaaa ttaacggttg cgccccggcc gtttttgccg tttaatgcaa accttgctgc
      961 accaagggcc aagaaagccg accggccgcc cccacagctt ccgatgcagg cggcccggcc
     1021 gtccctgcaa tgttttttat ttttgaacga aaggtcgaaa accatgaaaa aaacactggt
     1081 ggcggcggca atcctgagcc tcgccttgac tgcgtgcggc ggcggaagcg ataccgccgc
     1141 ccaccccccc tccgccaagc ccgaagccga acaatcgggc aaactcaata tctacaactg
     1201 gtcggattat gtcgatcccg aaaccgtcgc cgcctttgaa aaagaaaccg gcatcaagac
     1261 gcgttccgat tattacgaca gcaacgaaac actggaggca aaagtcctga ccggcaaatc
     1321 cagctacgac ctgaccgcgc cgtccatcgc caacgtcggc cggcaaatca aagcgggcgc
     1381 gtatcagaaa atcgacaagg cgcaaatccc ccattacggc aacatcgata aagatttgct
     1441 gaaaatgatg gaagccgtcg atccgggcaa cgaatacgcc gtcccctatt tctggggcat
     1501 caacaccttg gcaatcaaca cgcggcaggt gcaaaaggca ttgggtacgg acaagctgcc
     1561 cgaaaacgaa tgggatttgg tgttcaaccc cgaatacacc gccaaactca aatcctgcgg
     1621 catcagctat ttcgacagcg caatcgaaca gattcccttg gcgttgcact atttgggcaa
     1681 agaccccaac agtgaaaatc ccgaagacat caaagccgcc gtcgatatga tgaaagccgt
     1741 ccgaggcgac gtgaaacgct tcagctcttc cggctacatc gacgatatgg cggcgggcaa
     1801 cctgtgtgcc gccatcggtt acggcggcga tttgaacatt gccaaaaccc gtgccgaaga
     1861 agccgcaaac ggcgtggaaa tcaaagtatt gaccccgaaa accggcgtgg gcgtgtgggt
     1921 ggattccttt atgattccgc gcgacgcgca aaacgtcgcc aacgcccacc gctatatcga
     1981 ctacacgctc cggcccgagg tggcggcgaa aaacggcagc ttcgttacct acgcgcccgc
     2041 cagccgtccc gcgcgcgagc tgatggatga aaaatacacc tccgacgcat cgattttccc
     2101 gaacaaagaa ctgatggaaa aaagtttcat cgtatcgccc aaatccgcag aatccgccaa
     2161 actgggcgtg aagctgtggc aagggctcaa ggccggaaaa taaccgcaac ccctgccgtc
     2221 tgaaaccttt cgggcggcag gaaacggcgc gtccgttatc aaacaggggg gcgtttcccc
     2281 gcccgcctgt tatgattggg ttaagattaa aatgatttag tgaaatgaga aagatatgga
     2341 tttaagtatc gtagttccca tttataatgt cgagagttat ttggaagcgt gtctaaattc
     2401 catagaacct atattaagta atgaaaatgt cgaacttatc cttgtgaatg acgggtcaaa
     2461 agacggaagt gaagatatat gttataaata tatagat
//
LOCUS       DAXIDM010000167         2488 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000167 DAXIDM010000000
VERSION     DAXIDM010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2488
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.167"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..445
                     /locus_tag="ACFOAE_001983"
     CDS             <1..445
                     /locus_tag="ACFOAE_001983"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885390.1"
                     /translation="TVIPAKVGIQKRNATGIYRKKQKPPPRHSRAGGNPETQRNRNLS
                     EKTETPPTVIPAKAGIQQPKNHRNLSAKTETPTDRHSRAGGNPETQRGRTLSEKTETP
                     PTVIPAKAGIQKRNATGIYRKKQKPHRRHSRKSGNPDPSARKLTE"
     gene            618..2405
                     /locus_tag="ACFOAE_001984"
     CDS             618..2405
                     /locus_tag="ACFOAE_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR-type extended signal peptide-containing
                     protein"
                     /protein_id="HFC6885391.1"
                     /translation="MNKIYRIIWNSALNAWVVVSELTRNHTKRASATVETAVLATLLF
                     ATVQANATDTDEDDELEPVVRSALVLQFMIDKEGNGEIESTGDIGWSIYYDDHNTLHG
                     ATVTLKAGDNLKIKQNTDENTNASSFTYSLKKDLTDLTSVGTEELSFGANGNKVNITS
                     DTKGLNFAKKTAGTNGDTTVHLNGIGSTLTDTLAGSSASHVDAGNQSTHYTRAASIKD
                     VLNAGWNIKGVKTGSTTGQSENVDFVRTYDTVEFLSADTKTTTVNVESKDNGKRTEVK
                     IGAKTSVIKEKDGKLVTGKGKGENGSSTDEGEGLVTAKEVIDAVNKAGWRMKTTTANG
                     QTGQADKFETVTSGTNVTFASGKGTTATVSKDDQGNITVKYDVNVGDALNVNQLQNSG
                     WNLDSKAVAGSSGKVISGNVSPSKGKMDETVNINAGNNIEITRNGKNIDIATSMTPQF
                     SSVSLGAGADAPTLSVDDEGALNVGSKDANKPVRITNVAPGVKEGDVTNVAQLKGVAQ
                     NLNNHIDNVDGNARAGIAQAIATAGLVQAYLPGKSMMAIGGGTYRGEAGYAIGYSSIS
                     DGGNWIIKGTASGNSRGHFGASASVGYQW"
BASE COUNT          779 a          627 c          605 g          477 t
ORIGIN      
        1 gaccgtcatt cccgcaaaag ttggaatcca aaaacgcaac gcaacaggaa tttatcggaa
       61 aaaacagaaa cccccaccgc gtcattcccg cgcaggcggg aatccagaaa cacaacgcaa
      121 caggaattta tcggaaaaaa cagaaacccc accgaccgtc attcccgcaa aagcgggaat
      181 ccagcaaccg aaaaaccaca ggaatctatc agcaaaaaca gaaaccccca ccgaccgtca
      241 ttcccgcgca ggcgggaatc cagaaacaca acgcggcagg actttatcgg aaaaaacaga
      301 aaccccaccg accgtcattc ccgcaaaagc tggaatccaa aaacgcaacg caacaggaat
      361 ttatcggaaa aaacagaaac cccaccgccg tcattcccgc aaaagcggga atccagaccc
      421 gtcggcacgg aaacttaccg aataaaacag tttccttaga ttccacgtcc cagattcccg
      481 ccttcgcggg aatgacgaga ttttaagttg ggggaattta tcagaaaacc cccaaccccc
      541 aaaaaccagg cggatgccgc accatccgcc cccaaacccc gatttaacca ttcaaacaaa
      601 ccaaaagaaa aaacaaaatg aacaaaatat accgcatcat ttggaatagt gccctcaatg
      661 cctgggtcgt cgtatccgag ctcacacgca accacaccaa acgcgcctcc gcaaccgtgg
      721 agaccgccgt attggcgacg ctgttgtttg caacggttca ggcgaatgct accgataccg
      781 atgaagatga cgagttagaa cccgtagtac gctctgctct ggtgttgcaa ttcatgatcg
      841 ataaagaagg caatggagaa atcgaatcta caggagatat aggttggagt atatattacg
      901 acgatcacaa cactctacac ggcgcaaccg ttaccctcaa agccggcgac aacctgaaaa
      961 tcaaacaaaa caccgatgaa aacaccaatg ccagtagctt cacctactcg ctgaaaaaag
     1021 acctcacaga tctgaccagt gttggaactg aagaattatc gtttggcgca aacggcaata
     1081 aagtcaacat cacaagcgac accaaaggct tgaatttcgc gaaaaaaacg gctgggacga
     1141 acggcgacac cacggttcat ctaaacggta tcggttcgac tttgaccgat acgcttgcgg
     1201 gttcttctgc ttctcacgtt gatgcgggta accaaagtac acattacact cgtgcagcaa
     1261 gtattaagga tgtgttgaat gcgggttgga atattaaggg tgttaaaact ggctcaacaa
     1321 ctggtcaatc agaaaatgtc gatttcgtcc gcacttacga cacagtcgag ttcttgagcg
     1381 cagatacgaa aacaacgact gttaatgtgg aaagcaaaga caacggcaag agaaccgaag
     1441 ttaaaatcgg tgcgaagact tctgttatta aagaaaaaga cggtaagttg gttactggta
     1501 aaggcaaagg cgagaatggt tcttctacag acgaaggcga aggcttagtg actgcaaaag
     1561 aagtgattga tgcagtaaac aaggctggtt ggagaatgaa aacaacaacc gctaatggtc
     1621 aaacaggtca agctgacaag tttgaaaccg ttacatcagg cacaaatgta acctttgcta
     1681 gtggtaaagg tacaactgcg actgtaagta aagatgatca aggcaacatc actgttaagt
     1741 atgatgtaaa tgtcggcgat gccctaaacg tcaatcagct gcaaaacagc ggttggaatt
     1801 tggattccaa agcggttgca ggttcttcgg gcaaagtcat cagcggcaat gtttcgccga
     1861 gcaagggaaa gatggatgaa accgtcaaca ttaatgccgg caacaacatc gagattaccc
     1921 gcaacggcaa aaatatcgac atcgccactt cgatgacccc gcaattttcc agcgtttcgc
     1981 tcggcgcggg ggcggatgcg cccactttaa gcgtggatga cgagggcgcg ttgaatgtcg
     2041 gcagcaagga tgccaacaaa cccgtccgca ttaccaatgt cgccccgggc gttaaagagg
     2101 gggatgttac aaacgtcgca caacttaaag gtgtggcgca aaacttgaac aaccacatcg
     2161 acaatgtgga cggcaacgcg cgtgcgggca tcgcccaagc gattgcaacc gcaggtctgg
     2221 ttcaggcgta tctgcccggc aagagtatga tggcgatcgg cggcggcact tatcgcggcg
     2281 aagccggtta tgccatcggc tactcaagca tttccgacgg cggaaattgg attatcaaag
     2341 gcacggcttc cggcaattcg cgcggccatt tcggtgcttc cgcatctgtc ggttatcagt
     2401 ggtaagggct tttcgcctgt ctgctgtttg ggataggcgg aaggtttgaa gggaagggtg
     2461 gcgatttgcc gcctgagacc tttgcaaa
//
LOCUS       DAXIDM010000168         2428 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000168 DAXIDM010000000
VERSION     DAXIDM010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2428
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.168"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            662..1174
                     /locus_tag="ACFOAE_001985"
     CDS             662..1174
                     /locus_tag="ACFOAE_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFC6885392.1"
                     /translation="MKNFNGKLILIGLMGAGKTTLGRQMAQRLDYRFYDSDHEIAAAA
                     GVPIPTIFEMEGEQGFRSRETAILKKLVILPHIVLSTGGGAVLKEENRALIRKSGTVV
                     YLHAPPETLLERTRCDNSRPLLQVADPLAKLRELYAARDPVYRQTADFTVESANCRQT
                     VQTLLKRLSR"
     gene            1254..2333
                     /gene="aroB"
                     /locus_tag="ACFOAE_001986"
     CDS             1254..2333
                     /gene="aroB"
                     /locus_tag="ACFOAE_001986"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFC6885393.1"
                     /translation="MKTLTVHTPSHSYPIFIGNGLLPQAGSLLKPHLGKRAAIIANET
                     VAPLYLGTLQTALDAAGVSHFSIILPDGEAHKNWQTLNLIFDGLMQNRAERKTTLIAL
                     GGGVIGDMVGFAAATYQRGAPFVQIPTTLLSQVDSSVGGKTAINHPLGKNMIGAFYQP
                     QAVLADLDTLHTLPVRELSAGMAEVIKYGALGDIGFFEWLEQNISGLMTLDREKLAQA
                     VYRCCQMKADIVAQDETEQGIRAWLNLGHTFGHAIETEMGYGTWLHGEAIAAGCVLAA
                     RLSEQLGKTSAADTARLAALLEAAGLPSAPPVFAFEKWLEHMSHDKKVSGGIMRFIGL
                     NRLGEANITEITDTDILRRTLQPYL"
BASE COUNT          600 a          745 c          597 g          486 t
ORIGIN      
        1 aacccaaaac ggcaacttaa aaccccgtca ttcccgcgca ggcgggaatc taggtctgtc
       61 ggttcaggac cttatcggat aaaacggttt ctccaaccct gcgttctaga ttcccacttt
      121 cgtgggaatg acgggatatg ggtttccgtg cggacgtgtt cggatttccg cctgcgcggg
      181 aatgacggcg acagatgccc aacggtcttt atagtggatt aacaaaaatc aggacaaggc
      241 gacgaagccg cagacagtac aaatagtacg gaaccgattc acttggtgtt tcagcacctt
      301 agagaatcgt tctctttgag ctaaggcgag gcaacgctgt actggttttt gttaatccac
      361 tatagtattg ataaacatat tatcttcaat atattcaatt ggataattgt ttacctaagc
      421 aaagataatt gccttttcct gacaaataag tgaaatcaac ggattgtcaa aacacagcct
      481 gaaataaaaa acctccctga tttcttttat ttgtccttaa aatcagaaag gttcgggatg
      541 gtcgggttat ttttccaaac gtaccgccgc cctgccgatt tcgtataaaa ttccgccgta
      601 acccgacaag cccgaaccct gtcgccccga aaggcggggt gtcaaacatt aaggaattgt
      661 gatgaaaaac tttaacggca aactcatcct catcggactg atgggcgcgg gcaaaaccac
      721 gctgggccgg caaatggcgc agcggctgga ttaccgtttt tacgacagcg atcacgaaat
      781 cgccgcagcc gccggcgttc ccatccccac catatttgaa atggaaggcg aacagggatt
      841 ccgttcgcgc gaaaccgcca tactcaaaaa gctggttatc ctgccccata tcgtcctgtc
      901 caccggcggc ggcgcggtgt taaaagaaga aaaccgcgcc cttatccgca aaagcggcac
      961 ggtcgtctat ctgcacgccc cgcccgaaac cctgctcgaa cgcacgcgct gcgacaacag
     1021 ccgtcctttg ctgcaagttg ccgatccttt ggcgaaatta cgtgaactct acgccgcacg
     1081 cgaccccgtt taccgccaaa ccgccgactt taccgtagaa tcggcaaact gccggcaaac
     1141 cgtgcaaacc ctgctcaaac gcttatcccg ataaaccggc atatgcgccg cgcccagaaa
     1201 accaagccgc gccccgcccg gcgggccggc ggttcaaact ttaaggaaca acaatgaaaa
     1261 cactgaccgt acacaccccg tcccacagct accccatctt tatcggcaac ggactgctgc
     1321 cgcaggcagg aagcctgctc aaaccgcatt tgggcaaacg cgccgccatc atcgccaacg
     1381 aaaccgtcgc cccgctctac ctcggcacgc ttcagacggc attggatgcg gcaggcgtat
     1441 cccatttcag catcatcctg cccgacggcg aggcgcacaa aaactggcag acgctcaacc
     1501 tcatctttga cgggctgatg caaaaccgcg ccgaacgcaa aaccacatta atcgcactgg
     1561 gcggcggcgt gatcggcgac atggtcggct ttgccgctgc cacctaccag cgcggcgcac
     1621 cgttcgttca aataccgacc acactgttga gtcaagtcga ctcatcggtg ggcggcaaaa
     1681 ccgccatcaa ccacccgctc ggcaaaaata tgatcggcgc attctaccag ccgcaggcgg
     1741 tgcttgccga cttggacacg ctgcacaccc tgcccgtccg cgaattgtcc gccggtatgg
     1801 cggaagtcat caaatacggc gcgctcggcg acatcggttt tttcgaatgg ctcgaacaaa
     1861 acatatccgg actgatgacg ctcgatcggg aaaaactcgc ccaagccgtg taccgctgct
     1921 gccaaatgaa ggcagacatc gtcgcccaag acgaaaccga acagggcata cgcgcatggc
     1981 tcaacctcgg acacaccttc ggacacgcca ttgaaaccga gatgggttac ggcacttggc
     2041 tgcatggaga agccatcgcc gccggctgcg tgttggcggc gcgtttgtcc gaacaactgg
     2101 gcaaaacctc cgccgcagat accgcgcggc tcgccgccct gctcgaagcc gccggactgc
     2161 cgtccgcacc gcccgtgttt gcctttgaaa aatggctcga acatatgagc cacgataaaa
     2221 aagtcagcgg cggcatcatg cgctttatcg gtctgaaccg gctgggcgaa gccaacatca
     2281 ccgaaattac cgacacggac atcctccgcc gcaccctgca accgtatctc tgatttcctc
     2341 tgccgatgtg ctgccgcgcg ggtttgacgc acgatgatga ttttccatca tctttctccg
     2401 taaaagcggg aatccggtcc gttcggtt
//
LOCUS       DAXIDM010000169         2419 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000169 DAXIDM010000000
VERSION     DAXIDM010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2419
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.169"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(141..728)
                     /locus_tag="ACFOAE_001987"
     CDS             complement(141..728)
                     /locus_tag="ACFOAE_001987"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFC6885394.1"
                     /translation="MEHKLPQLPYEPDALSPHLSKETLEFHYGKHHQTYITNLNNQIK
                     GTEFENLPLEEIVKKSSGGVFNNAAQTWNHTFYWLGFTSKGQGKPAGELAAAIDAKWG
                     SFEKFQEAFNACAAGTFGSGWAWLVKTPAGGLDLVSTSNAATPLTTENTPLLTCDVWE
                     HAYYIDYRNSRPNYLKGFWEIVNWDEVAKRFAALS"
     gene            891..2297
                     /gene="dnaB"
                     /locus_tag="ACFOAE_001988"
     CDS             891..2297
                     /gene="dnaB"
                     /locus_tag="ACFOAE_001988"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFC6885395.1"
                     /translation="MNDYTAMPSEDREVGALSLPPHSMEAEQSVLGGLMLENPAWDRI
                     ADVVSGEDFYRHEHRLIFRSIAKLINESRPADVITVQEDLQRNEELEAAGGFEYLITL
                     AQNTPSAANIRRYAEIVRERSIMRQLAEVGTEIARSAYNPQGRDAGQLLDEAENKVFQ
                     IAESTAKSKQGFLEMPDLLKEVVQRIDMLYSRDNPDEVTGVPTGFIDLDKKTSGLQPG
                     DLIIVAGRPSMGKTAFSINIAEHVAVEGKLPVAVFSMEMGGAQLVMRMLGSVGRLDQS
                     VLKTGRLEDEHWGRLNEAVVKLSDAPVYIDETPGLTALELRARARRLARQFNNKLGLI
                     VIDYLQLMAGSGRSDNRASELGEISRSLKALAKELQVPIIALSQLSRTVESRTDKRPM
                     MSDLRESGAIEQDADLIMFMYRDEYYNQDSPMKGLAECIIGKHRNGPVGKIFLTWTGQ
                     FTKFDNAAYIPEEAKIED"
BASE COUNT          607 a          612 c          642 g          558 t
ORIGIN      
        1 tgacagtaac cgtagcaact gaaccgtcat tcccacggaa gtgggaatct agaaataaaa
       61 agcagcagga atttatcgga aataactgaa attcaatacc gcaaaaatct acccgaaatg
      121 atatagcgga ttaacaaaaa tcaggacaag gcggcgaagc gtttggcgac ttcgtcccag
      181 ttgacgattt cccagaaacc tttcaggtag ttgggacggc tgttgcggta gtcgatgtaa
      241 taggcgtgtt cccacacgtc gcaggtcagc agcggcgtgt tttcagtggt cagcggcgta
      301 gcggcgttgg aagtggaaac caaatccaat ccgccggcag gggtttttac cagccacgcc
      361 caaccggagc cgaaagtacc ggccgcgcag gcattgaacg cttcttggaa tttctcgaag
      421 ctgccccatt tcgcgtcgat ggcggcggcc agttcgccgg caggtttgcc ttgacctttg
      481 gacgtgaaac ccagccagta gaaggtgtgg ttccaagttt gcgctgcgtt gttgaacacg
      541 ccgcccgaag attttttcac aatctcttcc aaaggcaggt tttcaaattc ggtgcctttg
      601 atttgattgt tcaggttggt gatgtaggtt tgatggtgtt tgccgtagtg gaattccaaa
      661 gtctctttgc tcagatgcgg ggacaatgcg tccggttcat aaggcagttg cggcagctta
      721 tgttccattt tgtgctccta atattgtttt aaatgttgta ttttggcagt gttgctgcaa
      781 atagcttggc agcgcacata ttttacctgt tttgaggaat ggaaaccaat taaacctgct
      841 ttacgctata atagaagatt gcaatttcgg cacgacagat aggatgtacc atgaacgatt
      901 acacagccat gccgtctgaa gaccgtgagg tcggcgcatt gtcgcttccg ccgcactcaa
      961 tggaggcgga acaatccgtt ttgggcgggt tgatgctgga aaatccggca tgggacagga
     1021 ttgccgatgt ggtttcggga gaggatttct accggcatga acaccgcctg attttccgtt
     1081 ccattgccaa attaatcaat gagagccgtc ccgcagatgt gattacggtt caggaagatt
     1141 tgcagcggaa cgaagaattg gaagcggcag gcggattcga atacctgatt acgctggcgc
     1201 aaaacacccc gtctgccgcc aacatccgcc gctacgccga aatcgtgcgc gagcgttcca
     1261 ttatgcgcca actcgccgaa gtggggacgg aaatcgcccg cagcgcctac aatccgcaag
     1321 gcagggacgc ggggcagctt ttagacgagg cggaaaacaa agtattccaa atcgccgaaa
     1381 gcaccgccaa atccaagcag ggctttttgg agatgcccga tttgctgaaa gaagtcgtac
     1441 agcgcatcga tatgctctac tcgcgcgaca atcccgatga agttaccggc gtgccgacag
     1501 ggttcatcga cctcgacaaa aaaacctcgg gtctgcaacc cggcgacctg attatcgttg
     1561 ccggtcgtcc gtctatgggt aagaccgcct tttccatcaa tatcgccgaa cacgttgccg
     1621 tagaaggcaa gctgccggtt gctgttttct cgatggaaat gggcggtgcg caactggtca
     1681 tgcgtatgct cggctcggtc ggacgcttgg atcaaagcgt cctgaaaacc ggcaggctcg
     1741 aagacgaaca ctggggtcgt ctgaacgaag cagtcgtcaa actctccgac gcgcccgtgt
     1801 acatcgacga gaccccgggt ttgactgcgc tcgaactgcg cgcccgtgcc cgccgtctcg
     1861 cccgtcaatt taacaataag cttggattga ttgtcatcga ctacctgcaa ctgatggcag
     1921 gatccggccg ttccgacaac cgagcttcgg agctgggaga gatttcacgt tcgctcaaag
     1981 cgttggcgaa agaattgcaa gtccccatca tcgccctgtc gcaattgagc cgcacggtcg
     2041 aatcgcgtac cgacaaacgc ccgatgatgt ccgaccttcg cgaatccggt gctatcgagc
     2101 aggatgccga cctgattatg tttatgtacc gcgacgaata ctacaaccaa gactcgccca
     2161 tgaaaggcct tgccgaatgt atcatcggca aacaccgcaa cggtcccgtc ggtaaaatct
     2221 tcctcacatg gacgggacaa ttcaccaaat tcgacaatgc tgcctatatt cccgaggagg
     2281 caaagataga ggattaaatg gctatataaa aatttattag gcgaaatcag gcaaaatcgt
     2341 ttaaaatcat gctgagagat tgccctaaaa aataaaacgc ggtcttgagg catttttgca
     2401 ttcagcccgc atataattg
//
LOCUS       DAXIDM010000170         2298 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000170 DAXIDM010000000
VERSION     DAXIDM010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2298
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.170"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            435..510
                     /locus_tag="ACFOAE_001989"
     tRNA            435..510
                     /locus_tag="ACFOAE_001989"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:469..471,aa:Glu,seq:ttc)
     gene            895..1060
                     /locus_tag="ACFOAE_001990"
                     /pseudo
     CDS             895..1060
                     /locus_tag="ACFOAE_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216748.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
     gene            complement(1110..1916)
                     /gene="thiD"
                     /locus_tag="ACFOAE_001991"
     CDS             complement(1110..1916)
                     /gene="thiD"
                     /locus_tag="ACFOAE_001991"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFC6885396.1"
                     /translation="MKSSFVQTLTIAGSDSGGGAGIQADLKTFQMRGVFGTCVITAVT
                     AQNTLGVSAVHLVPTETITAQIQAIREDFDIRAYKIGMLGTAEIIECVADKLKHCDFG
                     RRVLDPVMIAKGGAPLLQDSAVAALTRLLLPDTDVLTPNLPEAEALTGVHIENRKDAE
                     RAAKILLDYGVKNVVIKGGHLNGSTSGRCTDWLFTQNETLELDSPRFPTAHTHGTGCT
                     FSACITAELAKGSDVCEAVRTAKSYITAAISNPLEIGAGHGPVNHWAYRD"
BASE COUNT          543 a          583 c          598 g          574 t
ORIGIN      
        1 ttatctgaaa gtttgaggtt ctagattccc gctttcgcgg gaatgacgaa aagtggcggg
       61 aatgacgaag tttcagacgg catcgcccgc ctgttttgat atggcggcac cccccccgac
      121 aaaaaaaaca atccggaacg catctgaccg ttccggattg ttttcaggcg aatccgccgc
      181 atcagaacat actgcgcacg cccatattga cctgccaagt ctggcgcatc gtgtgcatcg
      241 aagacctttg cgcctcaaaa taaagctgcc ttccgttgtc ggcattacca cgcaaaaaaa
      301 tgaattgctt gatattccaa tgttttttat atgtttttat attgtgatgc gatcagacaa
      361 acgcccccct gacatttgtt tagacggcat cgtattgcta aatttctata agtatgtata
      421 atgtccgttt ccacgcgccc atcgtctaga ggcctaggac actgcccttt cacggcggca
      481 accggggttc gaatccccgt gggcgtgcca attcaaaaac ctgcttgttt caagcaggtt
      541 tttttattat gaatcgtcat tcccgcaccc ttcgtcattc ccgcgaaagc gggaatctgg
      601 agcgcaggat taaagaaacc gttttatccg ataagcttcc gtgccgacag gtctggattc
      661 ccgcctgcgc gggaaggacg gcagagggtg gacgatgccg tctaaagcct gacaaggcat
      721 ttgatgccgt ctgaaacttc gtcattcccg cacccttcgt cattcccgca aaagcgggaa
      781 tctagagcgt agggttgaag aaaccgtttt atccaataag tttccgtgcc gacaggtctg
      841 gattcccact ttcgtgggaa tgacgagtct tttataacct gagacctttg caaaatgcct
      901 ttccctttta aatttaaaga ggggggagct gaaggattat tatcgggatt gggagctggt
      961 cgaatataaa gaagaattgg gcgcgatgca cgccaaagac gaaaacggca atccgatacg
     1021 gtttaaattt gtaaccatgc tggcgaaaaa gcctgaataa tcctcaaaaa tgccgtctga
     1081 acattttgtt tcagacggca tttttacgtc tagtcccgat acgcccaatg attgaccggg
     1141 ccgtgtcccg cgccgatttc caaagggttt gagattgccg ccgtaatgta ggacttggca
     1201 gtccgtacgg cttcgcaaac gtccgagcct tttgccaact cggcggtgat gcaggcggaa
     1261 aacgtgcagc ccgtgccgtg cgtgtgggcg gttggaaagc gcgggctgtc caattccagc
     1321 gtttcatttt gcgtaaacag ccaatccgtg cagcgtccgc ttgtgctgcc gttcaaatgt
     1381 ccgcctttga taacgacatt tttgacaccg taatcaagca ggatttttgc cgcacgttcc
     1441 gcatctttac ggttttcgat atgcacgccg gtcagggctt ccgcctcggg caggttgggg
     1501 gtcaatacat ccgtatcggg aagcagcagg cgcgtcagtg ccgcaacggc ggaatcctgc
     1561 aacagcggcg caccgccttt ggcaatcatc acagggtcga gtacgcgcct gccgaagtcg
     1621 cagtgtttca gcttgtcggc aacgcattcg atgatttccg ccgtgccgag cattcctatt
     1681 ttgtaggcgc ggatgtcaaa gtcttccctg attgcttgga tttgtgcggt gatggtttcg
     1741 gtcgggacga gatgaaccgc cgacacgccc aaggtatttt gcgcggtaac ggcggtgatg
     1801 acgcacgttc cgaacacgcc gcgcatctga aacgttttca aatccgcctg aatgcccgca
     1861 ccgccgcccg aatccgaacc ggcgatggta agcgtttgca caaaagagct tttcatttgt
     1921 tcctccttaa tattgtgtcc gataaaaagg gctaatgcct gtaaaaaagc acggcgatgc
     1981 cgtctgaaaa ccgcagcgcg gggtttgtgg tgcattatat gccgtattgc aggacaaggc
     2041 acagggcagg gcggcggggt gcatcgtagc aactgtattt ttgcccgacg gggtgaaaaa
     2101 tacagttgct acacccactg ataatgaaaa aagagagcaa tgccgtctga accgcgtgtt
     2161 gcggcgagca taaaccggca cgctttattc gtcattccca caaaaacaga aacctaaaat
     2221 tccgtcattc ctacgaaagc gggaatccag tgtgttcggt ttcagttgtt tttgggtttc
     2281 gggtgatttc caaatcga
//
LOCUS       DAXIDM010000171         2283 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000171 DAXIDM010000000
VERSION     DAXIDM010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.171"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(27..1436)
                     /gene="dacB"
                     /locus_tag="ACFOAE_001992"
     CDS             complement(27..1436)
                     /gene="dacB"
                     /locus_tag="ACFOAE_001992"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004175 - endopeptidase activity [Evidence
                     IEA];
                     GO_function: GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="HFC6885397.1"
                     /translation="MNFPKTAASLLLLLASLAAHALDTGRIPQNEIAVYVQELDSGKV
                     IIDHRSDVPVNPASTMKLVTAFAAFKTFGSNYRWATEFKSNGTVNDGTLDGNLYWAGS
                     GDPVFNQENLLAVQRQLREQGIRNITGHLMLDHSLWGEVGSPDDFEADSGSPFMTPPN
                     PTMLSAGMVMVRAERNAAGSTDILTDPPLPHIFAQNNLKITASQAACPSIKKLMRASF
                     SDNTLKLRGNIPESCLGKPVGVRMFALDELIRQSFTNHWLLGGGRISDGIGIADTPEG
                     AQTLAVAHAKPMKEILTDMNKRSDNLIARSVFLKLGGDGKLPAVSEQAASAVRRELAV
                     SGIDIADLVLENGSGLSRKERVTARMMAQMLETAYFSPFAQDFIDTLPIAGTDGTLRN
                     RFKQSGGLLRLKTGTLNNVRALAGYWLGDKPMAVVVIINSGRAVSLLPDLDNFVANNI
                     ISGGDGWLDAKLMCKERRA"
     gene            1601..2167
                     /locus_tag="ACFOAE_001993"
     CDS             1601..2167
                     /locus_tag="ACFOAE_001993"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003687372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFC6885398.1"
                     /translation="MAKKISILVGSLRRASFARKVALNAAEMFPEGWQAEIVEIGHLP
                     LYNFDYDDPAVEDVPLPESYTVFRETIKASDGILFVTSENNRTIPACLKNAVDIGSKP
                     NADVAWKNKPAGIISHSVGKMGGYSSQKNLRLALSYFDMPVTGQPEVFLGNSPTLFDE
                     NGKLIDSARDFVQSYINQFVGLIERNAK"
BASE COUNT          522 a          558 c          660 g          543 t
ORIGIN      
        1 aatttaatcc actatatttt cctgtttcag gctcggcgtt ctttgcacat cagtttcgca
       61 tccagccagc catcgccgcc ggagatgatg ttgttggcaa cgaagttgtc caagtcgggc
      121 agcagggaaa cggcgcggcc gctgttgatg atgacgacca ccgccatcgg tttgtcgccc
      181 agccaataac ctgcaagggc gcggacattg ttgagcgtgc cggtttttaa gcgcaacagc
      241 ccgccgcttt gtttgaagcg gttgcgtaaa gtcccgtctg tgccggcgat gggcagcgta
      301 tcgatgaaat cttgtgcaaa cgggctgaaa taagccgttt ccaacatttg cgccatcatt
      361 ctcgccgtta ccctttcttt tctggacaga cctgaaccgt tttccaaaac caaatccgca
      421 atatcgatgc ccgacacggc aagttcgcgc cggacggcag acgccgcctg ttcggaaacg
      481 gcgggcagtt tgccgtcgcc gccgagtttg aggaagacgg aacgcgcaat tagattgtcc
      541 gaacgcttgt tcatgtccgt caaaatttcc ttcatcggtt tggcgtgtgc aacggcaagc
      601 gtctgcgcgc cttccggcgt gtcggctatg ccgataccgt ctgaaatccg tccgccgccg
      661 agcagccagt ggttggtaaa actttgccgg atcagttcgt caagcgcgaa catccggaca
      721 ccgacaggct tgcccaaaca gctctcggga atattgccgc gcaatttcag cgtattgtcc
      781 gaaaaagatg cacgcatcag ttttttgatc gaagggcagg cagcttggga ggcggtaatt
      841 ttcaagttgt tttgggcgaa aatatgcggc aaaggcggat cggtgaggat gtcggtactg
      901 ccggcggcat tgcgttcggc gcgcaccata accataccgg cagacagcat agttggattg
      961 gggggcgtca taaacggcga accgctgtcg gcttcgaaat cgtcggggct gccgacttcg
     1021 ccccacaggc tgtggtcgag catcaggtgt cccgtgatat tgcgtatgcc ttgttcgcgc
     1081 aactggcgtt ggacggcaag caggttttcc tgattgaaaa cggggtcgcc gctgcccgcc
     1141 caatacaggt ttccgtcaag cgtgccgtcg tttaccgtac cgttgctttt aaactcggtc
     1201 gcccagcggt aattgctgcc gaaggttttg aaggcggcaa acgcggtaac gagtttcatt
     1261 gtggaggcgg ggttgacggg gacatccgag cggtggtcaa tgatgacttt tccgctgtca
     1321 agctcttgga catatacggc gatttcgttt tgcggaatgc gacccgtatc gagcgcgtgt
     1381 gcggcgaggg aggcgagaag cagcagcagg gaggccgctg ttttggggaa attcataggt
     1441 aaatctgtta cataaaaaaa gcaattataa ggcaaagccg gataagtggg aacgctgtgg
     1501 cggcgggccg gcttgtttgc aggggaaatc acatatataa taatcgctat cattatgaaa
     1561 tgattgagac gcacaaactt aatattcagg aggaatgatt atggctaaga aaatcagtat
     1621 tttggtgggc agcctgcgcc gagcttcttt tgcgcgcaaa gtggcattga atgcggcgga
     1681 gatgttcccc gaaggctggc aggcggaaat cgtcgaaatc ggacatctgc cgctttacaa
     1741 tttcgattat gacgaccctg cggtggaaga tgtgccgctg cccgaaagct acacggtttt
     1801 ccgcgaaacg attaaggctt cggacggcat tttgttcgtt acgtccgaaa ataaccgcac
     1861 cattcccgcc tgtttgaaaa atgcggtgga catcggctcg aaaccgaatg ccgacgtggc
     1921 gtggaaaaac aaaccggcag gcatcatcag ccattccgtc ggcaagatgg gcggttacag
     1981 ttcgcaaaaa aacctgcgcc ttgcgctgtc ttatttcgat atgcccgtaa ccggacagcc
     2041 ggaagtgttt ttgggcaatt cgccgacact gtttgatgaa aacggcaaat tgattgactc
     2101 ggcaagggat tttgttcagt catatattaa tcagtttgtc ggtttgattg aaagaaatgc
     2161 caaataaaca aaccaagtcg aaaggccgca aaaccggttc gggttttgcg gcttttttat
     2221 atgggctggg cagcgtcaag gtttgccgtt tgccggataa tgcgcggcaa atgaccggcg
     2281 tgt
//
LOCUS       DAXIDM010000172         2280 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000172 DAXIDM010000000
VERSION     DAXIDM010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.172"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..416)
                     /locus_tag="ACFOAE_001994"
     CDS             complement(<1..416)
                     /locus_tag="ACFOAE_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003686491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFC6885399.1"
                     /translation="MTHISSPRNEFIRGIKESSPILIGLLPWALILGMQGGQKGMSWL
                     EMLLMTSMNFAGGSEFATVNLWAESLPILLIATVTFMINSRHILMGAALALHLKEIPL
                     KKAVPALFFMCDESWAMAFSEIQKRKAAGLPAFNMP"
     gene            564..1016
                     /gene="dut"
                     /locus_tag="ACFOAE_001995"
     CDS             564..1016
                     /gene="dut"
                     /locus_tag="ACFOAE_001995"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004170 - dUTP diphosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006226 - dUMP biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0046081 - dUTP catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFC6885400.1"
                     /translation="MNIEVEMKVLDERMADFIPTYATAGSAGLDLRACLDEEVVLQPG
                     ETFLVPTGLAIYLANPSYAAVLLPRSGLGHKHGIVLGNLVGLIDSDYQGELKVSLWNR
                     SSEPFTVKPFERIAQMVIVPIVQARFKRVEEFVGSSRGEGGFGSTGLH"
     gene            1092..2279
                     /gene="dapC"
                     /locus_tag="ACFOAE_001996"
     CDS             1092..2279
                     /gene="dapC"
                     /locus_tag="ACFOAE_001996"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003752738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009016 - succinyldiaminopimelate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="HFC6885401.1"
                     /translation="MNTLLKQLKPYPFARLHEAMQGISAPEGMEAVPLHIGEPKHPTP
                     KVITDALTASLHELEKYPLTAGLPELRQACANWLKRRYDGLTVDADNEILPVLGSREA
                     LFSFVQTVLNPVSDGIKPAIVSPNPFYQIYEGATLLGGGEIHFANCPAPSFNPDWRSI
                     SEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFDGNK
                     PLGCLQAAAQLGRSRQKLLMFTSLSKRSNVPGLRSGFVAGDAELLKNFLLYRTYHGSA
                     MSIPVQRASIAAWDDEQHVIDNRRLYQEKFERVIPILQQVFDVKLPDASFYIWLKVPD
                     GDDLAFARNLWQKAAIQVLPGRFLARDTEQGNPGEGYVRIALVADVATCVKAAEDIVS
                     LYR"
BASE COUNT          548 a          542 c          600 g          590 t
ORIGIN      
        1 aaaggcatat tgaatgcggg caaaccggct gctttccgtt tttggatttc ggagaatgcc
       61 atcgcccagc tttcatcaca cataaaaaac agtgcgggca cggctttttt cagcggtatt
      121 tctttcaggt gcagggcaag tgccgccccc atcaggatat gccgcgaatt aatcataaag
      181 gttacggtgg cgataagcag tatcggcaga gattccgccc acaggttgac cgtggcaaac
      241 tcggagccgc cggcgaagtt catactggtc atcaacaaca tttccagcca gctcatgcct
      301 ttttgtccgc cctgcatacc gagtattaat gcccaaggca gaagtccgat aagtatgggc
      361 gaactttctt tgatgccgcg tataaattcg ttacggggcg agcttatgtg tgtcatatta
      421 taatattgat atgtaagaag gtcgggcatt atacacagac ggagtatttc aaaacaaaac
      481 ctatttgctg tgtttcagtg taaacacggc ttgtgtataa tccaccatct ttagacagac
      541 cgaccgtatg tgggagcaag gcaatgaata ttgaagtaga aatgaaagtg ttggacgaga
      601 ggatggcgga ttttatccct acctatgcga cagcgggttc tgccggtttg gacttgcgcg
      661 cctgtttgga tgaggaagtc gtcttgcagc cgggggaaac gtttcttgtg ccgacaggtt
      721 tggcaattta tttggccaat ccttcatatg ccgccgtttt gctgccccgt tccggcttgg
      781 ggcataaaca cggcattgtt ttgggcaatt tggtcggctt gattgactcc gattatcaag
      841 gggaattgaa ggtttcgtta tggaacagaa gcagcgagcc gtttactgtc aaaccgtttg
      901 agcgtatcgc gcagatggtt atcgtgccaa tcgtgcaggc gcgtttcaaa cgtgtcgagg
      961 aatttgtcgg aagcagccgt ggagaaggcg gtttcggcag tacgggtttg cattgaatat
     1021 aaaatgccgt ctgaagggca cgtcaggttc agacggcata tcttccgata taccgataac
     1081 cggagaaaat catgaatacc ttactcaagc agctcaaacc ctatcccttt gcccgactgc
     1141 acgaggcgat gcagggcatt tccgcgcctg aaggcatgga agccgtcccc ctgcacatcg
     1201 gcgaaccgaa acatccgaca ccgaaagtca ttacggatgc gctgaccgcc tcattgcacg
     1261 agttggaaaa atatccgctg actgcgggtc tgcctgaact gcgtcaggcg tgtgcaaact
     1321 ggttaaaacg ccgttacgat ggcttgacag tggatgcgga taatgaaatt ctgccggttt
     1381 taggcagtag ggaggcgttg ttttcttttg ttcaaaccgt gttgaaccct gtttcagacg
     1441 gcatcaaacc cgcaattgtc agcccgaatc ccttttatca gatttacgaa ggtgcgacac
     1501 ttttgggcgg cggtgaaatc cattttgcca attgccccgc gccgtctttc aaccccgatt
     1561 ggcgtagtat ttccgaagag gtttggaaac gcaccaaact ggtgttcgtc tgctcgccca
     1621 acaaccccag cggcagcgtg ctggatttgg acggatggaa agaagttttt gatttgcagg
     1681 acaaatatgg tttcattatt gcctcggacg aatgctattc cgaaatctat ttcgacggca
     1741 acaaaccttt aggctgcctg caggccgctg cacagttggg gcgaagcagg caaaaactgc
     1801 ttatgttcac cagtttgtcc aagcgttcca acgttccggg cctgcgttcc ggttttgtcg
     1861 ccggcgatgc cgaactgctt aaaaactttc tgctttacag aacctatcac ggcagtgcaa
     1921 tgagcattcc cgtgcagcgc gcaagcattg ccgcttggga tgacgaacag cacgttatcg
     1981 acaaccgccg cctgtatcag gaaaaatttg agcgcgttat tcccattttg caacaggtat
     2041 ttgacgttaa attaccggat gcctcgtttt acatctggtt gaaagtcccc gatggcgacg
     2101 atttggcatt tgcacgcaat ttatggcaaa aagccgctat ccaagtattg cccggacgtt
     2161 ttttggcacg ggataccgaa cagggcaatc ccggggaagg ttatgtccgt atcgctttgg
     2221 ttgccgatgt cgcaacttgt gtcaaagctg cggaagacat agtttcactg tatcggtaag
//
LOCUS       DAXIDM010000173         2245 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000173 DAXIDM010000000
VERSION     DAXIDM010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2245
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.173"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            109..792
                     /locus_tag="ACFOAE_001997"
     CDS             109..792
                     /locus_tag="ACFOAE_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HFC6885402.1"
                     /translation="MQHDVYDYTAHTVSKNTVLQKTYRLLGFSFIPAAAGAALAANAG
                     FNFYAAFGSRWIGFAVVLAFFYGMIHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQY
                     ALHIADGAKIVGIAAAMTAAVFLTMSALARRTRLDMNALGRFLTVGAVILMVAVVANL
                     FLGIPALALTISAGFVLFSSLMIMWQVRTVIDGGEDSHISAALTLFISLYNIFSSLLN
                     ILLSLNGED"
     gene            916..1428
                     /gene="coaD"
                     /locus_tag="ACFOAE_001998"
     CDS             916..1428
                     /gene="coaD"
                     /locus_tag="ACFOAE_001998"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003714602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFC6885403.1"
                     /translation="MLPNTPRRAVYAGSFDPPTLGHLWMIRQAQSMFDELIVAIGINP
                     DKRSTYTVAERQDMLCDITKMFPNVRTDVFENRFLVHYAREVDAGFIVRGIRSASDYE
                     YERSMRHINSDLAPEISTVFLMPPREIAEVSSTMVKGLVGPEGWTETVKRYVPPAVYQ
                     KMIAEHHNNA"
     gene            1464..2117
                     /locus_tag="ACFOAE_001999"
     CDS             1464..2117
                     /locus_tag="ACFOAE_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002248375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004730 - pseudouridylate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01621 family pseudouridine synthase"
                     /protein_id="HFC6885404.1"
                     /translation="MWEILFRHQDFVAINKPQGISVHRSDGEVSLTATLAAQLGVEKV
                     WLLHRLDKQTGGILLFALNPQSAAVLAAQFAERKMKKTYLALSDRKPSKKQGWIKGGM
                     EKSRRGMWKLTRNMENIAVTRFFSIRIGEKMRLFILEPHTGKTHQLRVAMKSLGSPIL
                     GDRLYGGTESETTFLYAWKIQFTYQQQEIEITAPLKNTWQAENISHALEEFYMAKAG"
BASE COUNT          592 a          573 c          530 g          550 t
ORIGIN      
        1 tttaaaatac gccggacaac tttatcttca cgcaaccgga caaattttga cattgggcaa
       61 tgttaaaatc ccccattatt cccaaccgcg ctttcaggag cagatgatat gcaacacgac
      121 gtttacgact acaccgcgca tacggtttct aaaaacaccg tcctgcagaa aacctaccgc
      181 ctgctcggat tttcattcat tccggcagcc gcaggcgcgg cacttgccgc caatgccggt
      241 ttcaattttt acgccgcctt cggttcgcgc tggatagggt ttgccgtcgt gttggcgttt
      301 ttctacggta tgatccactt catcgagaaa aaccgttaca gcaataccgg cgttaccctg
      361 ctgatggtat tcacattcgg tatgggcgta ttgatcggcc ccgtgctgca atacgcgctc
      421 catattgccg acggtgcgaa aatcgtcggc attgccgccg cgatgaccgc cgccgtcttt
      481 ttaacgatgt ccgccttggc gcgccgaacc cggctcgata tgaacgcgct cggacgcttc
      541 ctgaccgtag gtgcggtcat tctgatggtc gccgtggttg ccaatctgtt tttgggtatt
      601 cccgcactcg ccctgaccat ttccgccggt tttgtcttgt tcagttcctt aatgattatg
      661 tggcaggtac gcaccgtcat cgacggcggc gaagacagcc acatcagcgc ggcactgaca
      721 ctgtttatct cgctttacaa catcttcagc agcctgctga acatcctgtt gtctttaaac
      781 ggcgaggatt gatgccggta aaacgccgtc cgactatgcc gtctgaaaat gcttcagacg
      841 gcattttact ttgggcatac aatacggatg cacacgcacc aacacacagc cgactatgaa
      901 gccgggagga atcaaatgtt accgaataca ccgcgccgcg ccgtttatgc cggcagtttc
      961 gatccgccca cattggggca tctgtggatg atacggcagg cgcaatctat gtttgacgaa
     1021 ctcatcgtcg ccatcggcat taaccccgac aaacgcagca cctataccgt cgctgaaagg
     1081 caggatatgt tgtgcgatat tactaaaatg tttcccaacg tcagaaccga tgtatttgaa
     1141 aaccgatttc tggtgcatta cgcccgtgag gtagatgcag gattcatcgt gcgcggcatc
     1201 cgttctgctt cggattacga atacgaacgt tccatgcgcc atatcaacag cgacctcgcc
     1261 cccgaaatat ccaccgtatt cctcatgccg ccgcgcgaaa tcgccgaagt gtcgtccact
     1321 atggtcaaag gtttggtcgg gccggaaggc tggacggaaa ccgtcaaaag atatgtgccg
     1381 ccggccgtgt accaaaaaat gattgcagaa catcacaaca atgcctgaca gaaagcttct
     1441 gtcaaatata ttcaggttca aatatgtggg aaatcttatt cagacaccaa gattttgtcg
     1501 ccatcaataa accgcaaggc atatccgtcc accgttccga cggcgaagtc agcctgacgg
     1561 caacacttgc ggcacagttg ggcgtagaaa aggtatggtt gctgcacagg ttggacaaac
     1621 agaccggagg catattgctg tttgccctta atccccaaag tgccgctgtt cttgccgcac
     1681 agtttgccga aaggaaaatg aagaaaacct atttggcttt gtccgaccgc aaaccgtcca
     1741 aaaaacaagg atggataaaa ggcggcatgg aaaaatccag gcgcgggatg tggaagctga
     1801 cgcgcaatat ggaaaatatt gccgttaccc gttttttcag tatacgtatc ggtgaaaaaa
     1861 tgcggctgtt cattcttgag cctcatacgg gtaagacaca tcagctgaga gtggcaatga
     1921 aaagtctggg cagtcctatt ttgggggacc gcttatatgg agggacagaa tccgaaacta
     1981 cgttcctgta tgcatggaaa atacaattta cctatcaaca acaagaaatc gaaattactg
     2041 cacctttgaa aaatacatgg caggctgaaa atatctctca tgcgctggaa gaattttata
     2101 tggcaaaagc aggttaataa atataaatta atttataaac aatatgataa atatttttat
     2161 aaaaattttt caagaaaacg gttgaccgca aatctcttca agcgtatagt tcggttcttc
     2221 accgctgacg aagcggcggt aacga
//
LOCUS       DAXIDM010000174         2216 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000174 DAXIDM010000000
VERSION     DAXIDM010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2216
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.174"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            136..2016
                     /locus_tag="ACFOAE_002000"
     CDS             136..2016
                     /locus_tag="ACFOAE_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="HFC6885405.1"
                     /translation="MNIFYEESGQFKIAAIIQKNDATYQVDTPHGKRTKVKANNVFTE
                     FDGDMAAFLENAQAQAADIDTDLLWEVCGEEEFTAEAIAEEYYGHAPTKTELAATLIA
                     LYAAPMYFYKKAKGVFKAAPEETLKQALAAIERKKQQDAQIDAWAEALKRGEMPSEIA
                     ADLKTILHAPDKQSLTYKAFTKAADALKTSAYELAKKTGGITSIPQYLQDGFEIKYFP
                     KGTGFPDLPLPEMPDLPKADVTAFSIDDESTTEVDDALSLTDLDNGTKRVGIHIAAPS
                     LAIKQGDKMKKNIMERLSTVYFPGGKITMLPENWIAAFSLDAGAHRPAVSIYFDVDGE
                     FNVGAPTCKIEAVNISENLRIQAIEPHFNAEAGLDEAGEMMFAHHQDLIWFYQFAITL
                     QKARGKYEPNRAPQYDYSIELDKEDNVSVVRRERGSPIDTLVSEMMILANSTWAQMLH
                     DNDLPGLFRVQPTGKVRMSTKSEPHIGMGVQHYGWFTSPLRRAADYINQKQLISLIDD
                     TAEPLYQNSDAELFAALRDFDAAYTAYADFQRQMEAYWSLVYLQQQGTSELTATILKE
                     DLVRIEGLPLVTRATGIPFDALPKSQALFKITELDAEKQFVSLNYIKAVALAGKTAGN
                     AV"
     gene            2006..>2216
                     /locus_tag="ACFOAE_002001"
     CDS             2006..>2216
                     /locus_tag="ACFOAE_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilS"
                     /protein_id="HFC6885406.1"
                     /translation="MPSEARYGKLRQKQKPESHHSHSRESGFLGFRCFSVSMNFQAAV
                     PDKYPQSKIPSFPRRWESRFIRTETD"
BASE COUNT          603 a          673 c          519 g          421 t
ORIGIN      
        1 gtactggttt ttgttaatcc actataacgc aagcaccgca aagacgcgcc aaccctcccc
       61 caaccttttt tcagacggca ttttcggtaa tctgctaaaa tcgcccgctt gagtttccac
      121 agaaaaatcc gaaaaatgaa tattttttac gaagagtccg gccaattcaa aatcgccgcc
      181 atcatccaaa aaaacgacgc tacctaccaa gtcgataccc cacacggcaa acgcaccaaa
      241 gtgaaggcga acaacgtctt taccgagttc gacggcgata tggcggcgtt tttggaaaac
      301 gcgcaggcac aggcggcgga tatcgacacc gatttattgt gggaagtgtg cggcgaagag
      361 gaatttaccg ctgaagccat agccgaagaa tattacggcc atgcgccgac caaaaccgag
      421 ctggcggcga ccttgattgc gctgtacgcc gcgccgatgt atttctacaa aaaagccaaa
      481 ggcgtgttca aagccgcgcc cgaagaaact ttaaaacaag cacttgccgc catcgaacgc
      541 aaaaaacagc aagacgcgca aatcgacgct tgggcagaag ccttgaaacg cggtgagatg
      601 ccgtctgaaa tcgcggcgga tttgaaaacc atcctgcacg cgcccgacaa gcagtcgctg
      661 acctacaaag cctttaccaa agccgccgac gcgctgaaaa cctctgccta cgaattggcg
      721 aaaaaaacgg gcggcattac gtccattccc caatacctgc aagacgggtt tgaaatcaaa
      781 tacttcccca aaggaacagg cttccccgac cttccgcttc ccgaaatgcc cgacctgccc
      841 aaggctgacg ttaccgcctt ttccattgac gacgaatcga ccaccgaagt ggacgacgct
      901 ttaagcctga ccgacttgga caacggcacg aagcgcgtcg gcatccacat cgccgcgccg
      961 tcgcttgcca ttaaacaagg cgacaaaatg aaaaaaaaca tcatggaacg cttgagcacg
     1021 gtttatttcc ccggcggcaa aatcacgatg ctgcccgaaa actggattgc cgcgttcagc
     1081 cttgatgcag gcgcacaccg ccctgccgtc agcatttatt tcgatgtgga cggcgagttc
     1141 aacgtcggcg cgccgacctg caaaatcgaa gcggtcaaca tctccgaaaa cctgcgtatc
     1201 caagccatcg aaccgcattt caacgccgaa gcgggcttgg acgaagcggg cgaaatgatg
     1261 ttcgcccacc atcaagacct gatttggttt tatcaattcg ccatcaccct gcaaaaagcg
     1321 cgcggcaaat acgagcccaa ccgtgcgccg caatacgatt acagcatcga attggataaa
     1381 gaagacaacg tatccgtcgt ccgccgcgaa cgcggctcac ccatcgatac gctggtcagc
     1441 gagatgatga ttcttgccaa cagcacttgg gcacaaatgc tccatgacaa cgacctgccc
     1501 ggcctcttcc gcgtccaacc caccggaaaa gtacgcatga gcaccaaatc cgagccgcat
     1561 atcggcatgg gcgtgcagca ttacggctgg tttacctcgc cgctgcgccg cgccgccgac
     1621 tacatcaacc aaaagcagct gatcagcctg atagacgaca ctgccgagcc gctgtatcaa
     1681 aacagcgatg ccgagctttt cgccgcactg cgcgactttg atgccgccta taccgcctac
     1741 gccgatttcc aacggcagat ggaagcctac tggagccttg tgtacctgca acagcaaggt
     1801 acaagcgagc tgaccgcgac catcctcaaa gaagacctcg tccgcatcga aggcctgccg
     1861 ctggtcacgc gcgcgaccgg tattccgttt gacgcgctgc ccaaatcaca ggcattgttc
     1921 aaaatcaccg aattagatgc cgagaagcag tttgtctcgc tcaactacat caaggcagtc
     1981 gcactcgcag gcaaaacggc aggcaatgcc gtctgaagcc cgatacggca aactccggca
     2041 aaaacagaaa cctgaatctc atcattccca cagtcgggaa tccggttttt tgggtttccg
     2101 ttgtttttcc gtttcaatga acttccaagc cgccgttccc gataaatacc cgcaatctaa
     2161 aatcccgtca ttcccacgca gatgggaatc taggtttatc cgcacagaaa ctgata
//
LOCUS       DAXIDM010000175         2198 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000175 DAXIDM010000000
VERSION     DAXIDM010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2198
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.175"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..281)
                     /locus_tag="ACFOAE_002002"
     CDS             complement(<1..281)
                     /locus_tag="ACFOAE_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885407.1"
                     /translation="MVTDKYKLSLEENIFLAKKVLVAQIHNLSRFENCQTTLLQTEQI
                     IHGKNVASVSLEDIQTILNLKRAYQYVISHISNGEPVNISLLKKINNIVA"
     gene            complement(406..939)
                     /locus_tag="ACFOAE_002003"
     CDS             complement(406..939)
                     /locus_tag="ACFOAE_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HFC6885408.1"
                     /translation="MSPTHEISNVERLIDEINRIHAGYHERVSKLYGGNFPNLSKMLR
                     HLDIDFVLQYRLNLHESINDYLIRFDIGDLPLAYYYRVKTTESVFDKIRRFSEREPGY
                     PANKVLNDIFGVRIIADSALMDEIHAALDEWVSTKGLKNWYVQEKTAISERMCTSIKE
                     IICFFRGNFRYGIRRMP"
     gene            complement(1252..1524)
                     /locus_tag="ACFOAE_002004"
     CDS             complement(1252..1524)
                     /locus_tag="ACFOAE_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885409.1"
                     /translation="MNKRIKICPACQQGYLYHSKPKYLHDEIILCDECDAVWLKGMNI
                     FYGEYEKDFYSYVPFMESQGITSECIWEGDLFDHPYYEDENSNDMD"
     gene            complement(1711..>2198)
                     /locus_tag="ACFOAE_002005"
     CDS             complement(1711..>2198)
                     /locus_tag="ACFOAE_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885410.1"
                     /translation="KKDIFYCEQWSYGYKRLHKPFSEKQAEEKHLKGELYTAVIGSAT
                     QPEYVITLREEVGFFSVNFFDKFGRDYLTHQFQKYSNSNYYFLSTAVWRDYITLESHD
                     LAEGYTYFFNENTDDCYVLKQDFINNERYEKTELYPQKDKVILFPKFGEYDLVLNPDI
                     I"
BASE COUNT          698 a          452 c          352 g          696 t
ORIGIN      
        1 gcaacaatgt tgttgatttt tttaaggagt gaaatattga ccggttcgcc atttgaaata
       61 tgcgaaatca catattgata ggcacgtttc aggttcaaga tggtttggat gtcttcaagt
      121 gacacggagg ctacattttt gccatggata atttgctcag tctgcaataa ggtcgtctga
      181 caattctcaa aacggctgag gttgtgaatt tgggcaacca atactttctt tgccagaaaa
      241 atattttctt ccaaactcaa cttgtatttg tccgtaacca cgagagttcc tttaataatt
      301 aaatctgtac acccaaggta tgcacggtaa acggtgctat attaaaaaga cccattaaag
      361 gttaaacaaa aagtcgcttg tcccgttcat ggctctcaat atttttcaag gcatccgcct
      421 tatcccatat ctgaagttcc cacggaaaaa acagattatt tctttgattg aagtacacat
      481 gcgttccgat atagccgttt tttcctgaac gtaccagttt tttaaaccct tcgtcgaaac
      541 ccattcatct aaagcagcat gtatttcgtc cattagcgcg gaatcagcga tgattctcac
      601 cccaaaaata tcatttaaca ccttattcgc cggatacccg ggctcgcgtt ccgaaaaccg
      661 gcggattttg tcgaaaacgg actccgtggt tttaacgcgg tagtagtatg ctaaaggcaa
      721 gtccccgatg tcaaatcgaa tcagatagtc gttgattgac tcatgcaaat taagtcggta
      781 ttgcaacaca aaatcgatgt ccagatgacg gagcatcttt gacaaattgg gaaagtttcc
      841 gccatacagt ttggaaaccc tttcgtgata tccggcgtgt atgcggttaa tttcgtcaat
      901 cagccgttct acattactga tttcatgagt gggggacatt ccttattact ctttcattcc
      961 aattatatga aaataacata ctaattgctt tcaactatat attatacaaa acaaatttca
     1021 aaacttcctt ttaatttttc attaccgtta atacgctaaa acaggaggaa tcgcaaatcc
     1081 aaaaaacata cacggtaaca gattacaggt catcaatgaa tccaatccat cccatgaaga
     1141 caaaggagcg actactcggc atccaagcag cctccggtac ggaaaacgac attgcattaa
     1201 agacagcgcc gtttgatggc taatcgtacc tacgcaggct taaaatttcc atcaatccat
     1261 atcatttgag ttttcatctt cataatatgg atgatcaaac aaatctcctt cccaaataca
     1321 ttcactcgtt ataccttggg attccatgaa aggaacataa gaataaaaat ctttttcata
     1381 ttctccataa aatatattca tacctttgag ccatactgca tcgcattcat cacacagaat
     1441 aatttcatca tgaagatatt taggtttcga atggtagaga tagccttgtt gacaagcggg
     1501 acatattttt attctcttat tcatgattac tccatataat caatttattt ttgtgggtaa
     1561 gcagtagtga tttgattgct gcctttagtc tgtacaacaa tacgtatata gcaacctgat
     1621 aatttcctgg tttttatcag ctttatcctc agattccaaa cccaataata aaagccgtct
     1681 gaaatttttt cagacggcct taaaactcaa ttaaataatg tccggattta acaccaaatc
     1741 atattcacca aactttggaa atagaattac cttatctttt tggggatata attctgtttt
     1801 ttcatatcgc tcattattaa taaaatcttg tttcaaaaca tagcaatcat ccgtattttc
     1861 attgaagaaa taagtatatc cttctgctaa gtcatgagat tccaaagtta tataatctct
     1921 ccatacagcc gtagaaagaa aataataatt cgaattggaa tatttttgaa attgatgggt
     1981 taaataatcc cttccaaatt tatcgaaaaa atttaccgaa aaaaaaccta cttcctctcg
     2041 caaggtaatt acatattcag gttgtgtcgc cgaacctatt acggcagtat ataactcccc
     2101 tttaagatgt ttttcctcag cttgtttctc agaaaaaggc ttatgaagtc tcttataacc
     2161 ataagaccac tgctcacaat aaaaaatatc tttcttca
//
LOCUS       DAXIDM010000176         2048 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000176 DAXIDM010000000
VERSION     DAXIDM010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.176"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(12..1850)
                     /gene="glmS"
                     /locus_tag="ACFOAE_002006"
     CDS             complement(12..1850)
                     /gene="glmS"
                     /locus_tag="ACFOAE_002006"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFC6885411.1"
                     /translation="MCGIVGAIRAHHNVVDFLTDGLKRLEYRGYDSSGIAVNTDGKIK
                     RVRRVGRVQLMEDAAREKGISGGIGIGHTRWATHGGVTEPNAHPHISGGMIAVVHNGI
                     IENFESERKRLEGLGYRFESQTDTEVIAHSINHEYAQNGGRLFEAVQEAVKRFHGAYA
                     IAVIAQDKPDELVVARMGCPLLVALGDDETFIASDVSAVIAFTRRVAYLEDGDIALLA
                     SDGIKRLTDKNGLPAERKVKVSELSLASLELGLYSHFMQKEIHEQPRAIADTAEVFLD
                     GGFIPENFGKDAKSVFESIRSVKILACGTSYYAALTAKYWLESIAKIPADVEIASEYR
                     YRSVIADPDQLVITISQSGETLDTMEALKYAKSLGHRHSLSICNVMESALPRESSLVL
                     YTRAGAEIGVASTKAFTTQLVALFGLAVTLAKVRGLVSEEDEARYTEELRQLPGSVQH
                     ALNLEPQIAAWAQQFAKKTSALFLGRGIHYPIALEGALKLKEITYIHAEAYPAGELKH
                     GPLALVDENMPVVVIAPNDSLLDKVKANMQEVGARGGELFVFADLDSNFNATEGVHVI
                     RAPRHVGELSPVVHTIPVQLLAYHTALARGTDVDKPRNLAKSVTVE"
BASE COUNT          397 a          550 c          626 g          475 t
ORIGIN      
        1 accggcggga tttattcgac ggttacggat tttgccagat ttcgcggttt gtccacatcc
       61 gtgcctcggg cgagggcggt gtggtaggcg agaagctgca cggggatagt atgcacgacg
      121 ggggacagtt cgccgacatg gcgcggcgca cggataacgt gcacgccttc ggtggcatta
      181 aaattgctgt cgaggtcggc aaagacgaaa agttcgccgc cgcgtgcgcc gacttcctgc
      241 atattggctt tgactttgtc caacaggctg tcgttgggcg cgatgacgac gacgggcatg
      301 ttttcgtcca ccagggcaag cggcccgtgc ttcagttcgc cggcaggata ggcttcggcg
      361 tggatgtagg tgatttcctt cagttttaac gcgccttcga gggcaatcgg gtaatggatg
      421 ccgcgcccta aaaacagcgc gctggttttc ttggcaaact gttgcgccca agcggcaatt
      481 tgaggttcga ggttcaaagc gtgctgcacg ctgccgggaa gctggcggag ttcttcagtg
      541 taacgcgctt cgtcttcttc ggaaaccaaa ccgcgtacct tcgccagcgt taccgccaaa
      601 ccgaacagtg cgaccagctg cgtggtaaac gccttggtcg aggcgacgcc gatttccgca
      661 ccggcacggg tataaagcac gaggctgctt tcgcgcggca gggcggattc catcacgttg
      721 cagatggaga ggctgtggcg gtgtcccaag gatttggcgt atttcaaagc ttccatcgtg
      781 tccagcgttt caccggattg ggaaatggta atgaccagtt ggtcgggatc ggcaatcacg
      841 ctgcggtatc ggtattcgct ggcgatttcg acgtcagccg ggattttggc gatggattcc
      901 aaccaatatt tggcggtcag cgcggcgtaa taggacgtgc cgcaggcaag gattttgacg
      961 ctgcggatgc tttcaaacac gcttttggca tctttgccga agttttcggg gatgaagccg
     1021 ccgtcgagga aaacctccgc cgtgtctgca atcgcgcggg gctgctcgtg gatttctttt
     1081 tgcataaagt ggctgtacag tcccagttcc aaagaggcga gcgagagttc ggataccttg
     1141 actttgcgtt cggcaggcag gccgttttta tcggtcagcc ttttgatgcc gtctgaagcc
     1201 agcagcgcga tgtcgccgtc ttcgaggtac gccacgcggc gcgtaaaggc gatgacggcg
     1261 gatacgtccg aagcgataaa ggtttcatcg tcgcccaaag cgaccaaaag cgggcagccc
     1321 atacgcgcca cgactaattc atcaggcttg tcttgggcaa taaccgcgat ggcatatgcg
     1381 ccgtggaaac gtttgaccgc ttcctgcact gcttcaaaca gcctgccgcc gttttgcgcg
     1441 tattcgtgat tgatgctgtg ggcgatgact tcggtatccg tttgcgattc aaaacggtat
     1501 cccaaacctt ccaaacgttt gcgttcgctt tcaaagtttt cgatgatgcc gttgtggacg
     1561 acggcaatca taccgccgct gatgtgcggg tgggcgttcg gctcagtaac gccgccgtgt
     1621 gtcgcccaac gcgtatgtcc gatgccgatg ccgccgctga tgcctttttc gcgtgccgcg
     1681 tcctccataa gctgcacgcg tccgacgcgg cgcacgcgtt tgattttgcc gtcggtgttg
     1741 acggcaatgc ctgatgagtc ataaccccgg tattcgaggc gtttgaggcc gtcggtcaga
     1801 aaatcgacga cgttgtgatg ggcgcggatg gcgccgacga taccgcacat aactgttcct
     1861 tagtatccgg ttgaaaaaaa acaggcgcgg acggctcccg tgccgcacct tcctcttcgg
     1921 attataaacc gcctcccgcg ccgaaaaaca gcaaaatgcc gtctgaaggc ttgggcttgc
     1981 tcaaaaaagg agggatttcc ctgcctgacc gggatgggcg ttcagacggc attgcctgct
     2041 gccggttt
//
LOCUS       DAXIDM010000177         2021 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000177 DAXIDM010000000
VERSION     DAXIDM010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.177"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..264
                     /locus_tag="ACFOAE_002007"
     CDS             <1..264
                     /locus_tag="ACFOAE_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885412.1"
                     /translation="VIANSAWGLLLNLSCYYDEVLEKRKIPFGKQEIDDDMDKVSALK
                     RKFKDISEIKVGDGWECPFNYEQGMKELDEVLLKYIPFFEEER"
     gene            276..581
                     /locus_tag="ACFOAE_002008"
     CDS             276..581
                     /locus_tag="ACFOAE_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002213559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885413.1"
                     /translation="MRVSKIIGSMLLVTAVQTVFSANVYACRHNGKTSYSQTPGKHCT
                     NAGLGRDLVYSSVRPAVKDRAEDAGVGDYSDTVRDEHVQNPRENTHKDASNTGAKTH"
     gene            643..2019
                     /gene="mpl"
                     /locus_tag="ACFOAE_002009"
     CDS             643..2019
                     /gene="mpl"
                     /locus_tag="ACFOAE_002009"
                     /EC_number="6.3.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HFC6885414.1"
                     /translation="MKHIHIIGIGGTFMGGIAAIAKEAGFEVSGCDAKMYPPMSTQLE
                     ALGIDVHEGFDAAQLDEFKADIYVIGNVAKRGMDVVEAILNRGLPYISGPQWLSENVL
                     HHHWVLGVAGTHGKTTTASMLAWVLEYAGLAPGFLIGGVPENFSVSARLPQTPRQDPN
                     SKSPFFVIEADEYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFADLGAIQTQFHHL
                     VRTVPSEGLIVCNGQQQSLQDTLDKGCWTPVEKFGTEHGWQVGEVNADGSFDVLLDGK
                     KAGHVAWDLMGGHNRMNALAVIAAARHAGVDIQTACEALSAFKNVKRRMEIKGTVNGI
                     TVYDDFAHHPTAIETTIEGLRQRVGNARILAVLEPRSNTMKLGTMKAALPESLKDADQ
                     VFCYAGGVDWDVAEALAPLGGRLHVGKDFDAFVAEIVKNARTGDHILVMSNGGFGGIH
                     TKLLDALR"
BASE COUNT          524 a          513 c          548 g          436 t
ORIGIN      
        1 gtaattgcaa atagtgcttg ggggctattg cttaatttat cttgttatta tgacgaggtt
       61 ttggaaaagc ggaaaatacc gttcggcaaa caggaaattg atgacgatat ggacaaagtg
      121 tccgccctta agcggaagtt taaagatatt tctgaaatca aagtagggga tggttgggaa
      181 tgcccgttca attatgagca gggaatgaaa gaattagatg aagtgctatt gaaatacatt
      241 cccttttttg aagaagaacg ataaaggagg ttgatatgcg cgtatctaaa ataattggaa
      301 gtatgttgct tgttacagcg gttcagaccg tattttcggc aaatgtttac gcgtgccgcc
      361 ataatggtaa aaccagttac agccaaactc cgggaaaaca ttgtaccaac gcgggtttgg
      421 ggcgggacct ggtgtacagt tcggttagac cggcagtaaa agacagggcg gaagacgcag
      481 gggtcggcga ttattcggac acggtgaggg acgaacacgt ccaaaatccg agagagaata
      541 cgcataagga tgcttcgaat accggtgcaa agacgcattg attgaaaccg aatcagccat
      601 gacggcgttg aataatagaa tttgaacgat tagggaactc tgatgaaaca catccacatt
      661 atcggtatcg gcggcacgtt tatgggtggg attgccgcca ttgccaaaga agcagggttt
      721 gaagtcagcg gttgcgatgc gaagatgtat ccgccgatga gcacccagct tgaagccttg
      781 ggcatagacg tacacgaagg cttcgatgcc gctcaattag acgaatttaa agccgatatt
      841 tacgttatcg gtaatgttgc caaacgcggc atggatgtgg ttgaagcgat tttgaaccgc
      901 ggcctgcctt atatttccgg cccgcaatgg ctgtcggaaa acgtattaca ccatcattgg
      961 gtactcggcg tagccggcac acacggcaaa acgaccaccg cttccatgct cgcctgggtc
     1021 ttggaatatg ccggactcgc gccgggcttc ctgattggcg gcgtaccgga aaacttcagc
     1081 gtttccgccc gtctgccgca aacgccgcgc caagacccga acagcaaatc gccgtttttc
     1141 gtcatcgaag ccgacgaata cgacactgcc ttttttgaca aacgctccaa attcgtgcat
     1201 taccgtccgc gtaccgccgt gttgaacaat ctcgaattcg accacgccga catctttgcc
     1261 gacttaggcg cgatacagac ccagttccac cacctcgtgc gcaccgtacc gtctgaaggc
     1321 ttaatcgtct gcaacggcca acaacaaagc ctgcaagata ctttggataa aggctgctgg
     1381 acgccggtgg aaaaattcgg cacggaacac ggctggcagg tcggtgaagt caatgccgac
     1441 ggctcgtttg atgtgttgct tgacggcaaa aaagccggac acgtcgcttg ggatttgatg
     1501 ggcggacaca accgcatgaa cgcgcttgcc gttatcgccg ccgcacgtca tgccggcgtc
     1561 gatattcaga cggcctgcga ggccttgagc gcgtttaaaa acgtcaaacg ccgcatggaa
     1621 atcaaaggca cggtgaacgg catcaccgtt tacgacgact ttgcccacca tccgaccgcc
     1681 atcgaaacca ccatcgaagg cctgcgccag cgcgtcggaa acgcccgcat cctcgccgtc
     1741 ctcgagccgc gttccaacac catgaaactc ggcaccatga aagctgccct gcccgaaagc
     1801 ctcaaagatg ccgaccaagt gttctgctac gccggcggcg tggactggga tgtcgccgaa
     1861 gccctcgcac ctttgggcgg caggctgcac gtcggcaagg atttcgatgc cttcgttgcc
     1921 gaaattgtga aaaacgcccg aaccggcgac catattttgg tgatgagcaa cggcggtttc
     1981 ggcggaatac acaccaaact gctggacgct ttgagatagc c
//
LOCUS       DAXIDM010000178         2017 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000178 DAXIDM010000000
VERSION     DAXIDM010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.178"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(331..654)
                     /locus_tag="ACFOAE_002010"
     CDS             complement(331..654)
                     /locus_tag="ACFOAE_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFC6885415.1"
                     /translation="MDMVVRGGIYLVSLDPTVGSEIKKTRPCVVVSPPEIHNYLKTVL
                     IVPMTSGSRPAPFRVNVRFQDKDGLLLPEQIRAVDKAGLVKHLGNLDNSTAEKLFAVL
                     QEMFA"
     gene            complement(673..882)
                     /locus_tag="ACFOAE_002011"
     CDS             complement(673..882)
                     /locus_tag="ACFOAE_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="growth regulator"
                     /protein_id="HFC6885416.1"
                     /translation="MILNIRKMGNSQGVILPKSLLGQIGAVDSLAVTVEKGNIILSCP
                     TVRRGWAEAAAMLVETEQEHFFFRN"
     gene            complement(1005..1802)
                     /gene="truA"
                     /locus_tag="ACFOAE_002012"
     CDS             complement(1005..1802)
                     /gene="truA"
                     /locus_tag="ACFOAE_002012"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003703378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFC6885417.1"
                     /translation="MDTAQKQRWAITLSYDGSRFYGWQKQADGVPTVQAALENALAQI
                     AGEAVSTIVAGRTDTGVHATAQVVHFDTTAARPQQAWVRGVNAHLPEGIAVLHARQVA
                     PEFHARFDAYGRHYRYLLESVPVRSPLLKNRAGWTHLKLDIEPMRRAAAYLIGEQDFS
                     SFRAAECQAKSPVKTIYRADLTQSSGLVRLDLHGNAFLHHMVRNIMGALVYVGSGRLS
                     VEGFAALIQERSRLKAPPTFMPDGLYLTGVDYPEAYGIVRPQIPEWL"
BASE COUNT          458 a          479 c          571 g          509 t
ORIGIN      
        1 accgtcattc ccgccacttt tcgtcattcc cgctcaggcg ggaatctaga atctcggact
       61 ttcagataat ctttgaatat tgccgctgcc ttaaggtctg gattcccgcc tgcgcgggaa
      121 tgacggctgc agatgcccga cggtctttat agtggattaa caaaaatcag gataaggcga
      181 cgaagccgca gacagtacaa atagtacgga accgattcac ttggtgcttc aacaccttag
      241 agaatcgttc tctttgagct aaggcgaggc aacgccgtac tggtttttgt taatccacta
      301 taatgaacac aatccattca gactattcaa tcaggcaaac atctcctgca atactgcaaa
      361 cagtttttca gccgtactgt tgtctaaatt tccaagatgt ttgaccaatc cggctttatc
      421 cacagcccta atttgttcgg gtaaaagcaa accgtcttta tcctgaaagc ggacattgac
      481 gcggaacggg gcaggacggc ttccgctcgt cataggaacg atcagcacag tcttgagata
      541 gttgtgtatt tcaggaggag agactacgac acaaggacgt gtctttttga tttcgcttcc
      601 tacggtcggg tctaaggaga ccagatagat tccgccgcgt actaccatat ccattcttta
      661 tccgcttcgt tttcaatttc ggaaaaaaaa atgctcctgc tcggtttcga caagcattgc
      721 ggcagcttct gcccatcccc tgcgaacggt aggacagctt aaaataatat tgcccttttc
      781 aactgtaaca gccaagctgt ctactgcccc tatttgaccc aataatgatt tgggcagaat
      841 cacgccttgc gagtttccca ttttgcgtat gttgagaatc atatacgtac catatttacc
      901 tgtttatgta ataacaatgt tagtaccttg atgaggtagt gtcaacatgg aaaaagattg
      961 cctgacagtt tgtccgattt caaaatctcc gcgacaagaa tgttttaaag ccattcgggg
     1021 atttgggggc ggacgatgcc atatgcctcg ggatagtcga cgccggtcag gtagagtccg
     1081 tcgggcatga aggtcggtgg ggctttgagg cggctgcgtt cttgaatcag tgcggcgaag
     1141 ccttcgacgc tgagtctgcc gctgccgaca taaacgagcg cgcccatgat gttgcgtacc
     1201 atatggtgca aaaaggcgtt gccgtgcaaa tcgaggcgga cgagtcctga gctttgggta
     1261 aggtcggcgc ggtagatggt tttgacgggg gattttgctt ggcattcggc ggcgcggaag
     1321 ctggagaagt cttgttcgcc gatcaaatag gcggcagccc gacgcatcgg ttcgatgtcg
     1381 agtttgaggt gtgtccagcc tgccctgttt ttgagcaggg gggaacggac ggggacggat
     1441 tcgagcaggt agcggtaatg ccgtccgtat gcgtcgaagc gggcgtgaaa ttcgggggcg
     1501 acctgtcggg cgtgcaaaac ggcaatgcct tcgggcaggt gggcatttac gccgcgcacc
     1561 catgcctgtt ggggacgggc ggcagttgtg tcgaagtgga cgacttgggc ggtggcatgc
     1621 acgccggtgt cggtcctgcc ggcaacaatg gtggaaaccg cttcccctgc tatttgggca
     1681 agtgcgtttt ccaatgccgc ctgaacggtc ggtacgccgt cagcctgttt ctgccagccg
     1741 taaaagcggc tgccgtcata ggatagggtt attgcccagc gttgtttttg tgcggtatcc
     1801 atcggatttg ggattcggat aaatgttcag actgcattgt atcgcagatt ttgcagggaa
     1861 acggcaaacg cccggggcga gcggcgttgt ttggggagtt ggggggggtg gatgcagttg
     1921 ctacgaatcg ctatcctgtg aattcaccct gtcaggagtg cccgaatcgt cattcccgcg
     1981 caggcgggaa tctaggacgt aaaatctaaa gaaacca
//
LOCUS       DAXIDM010000179         2002 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000179 DAXIDM010000000
VERSION     DAXIDM010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.179"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(191..667)
                     /locus_tag="ACFOAE_002013"
                     /pseudo
     CDS             complement(191..667)
                     /locus_tag="ACFOAE_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IgG-binding virulence factor TspB family
                     protein"
     gene            complement(1015..1293)
                     /locus_tag="ACFOAE_002014"
     CDS             complement(1015..1293)
                     /locus_tag="ACFOAE_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885418.1"
                     /translation="MYYQVGNKCLEKHQAENLYFSLVVPRIKENGQIVRPEYNGSLWK
                     MSDGQPLRLLLAECSPKDNLQSGLETGWIVFGILASVYFVSLLKKVLK"
     gene            complement(1300..1518)
                     /locus_tag="ACFOAE_002015"
     CDS             complement(1300..1518)
                     /locus_tag="ACFOAE_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFC6885419.1"
                     /translation="MKFINTCRKYGAKLAVVTAAPLALAAHANATLPDTAKNALEAAK
                     ADGMEAGWIVVGIFAALFVFSIVKRVMK"
     gene            complement(1592..1789)
                     /locus_tag="ACFOAE_002016"
     CDS             complement(1592..1789)
                     /locus_tag="ACFOAE_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885420.1"
                     /translation="MQKVYVVQSVSTGDFLYLSPETVDIGHTKLITNADYFYDFEEAI
                     NAGLEEIGNQYEFVVFGFLKD"
     gene            complement(1794..>2002)
                     /locus_tag="ACFOAE_002017"
     CDS             complement(1794..>2002)
                     /locus_tag="ACFOAE_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885421.1"
                     /translation="LIVATPLDSSQGNALGSSTTEYDFGGSANFEQFRNAQFPIEANL
                     NVEIVTTGKTQKLKVIGFQPVKKG"
BASE COUNT          578 a          468 c          380 g          576 t
ORIGIN      
        1 ccggagacct ttgcaaaatt cctttccctc ccgacagccg aaacccaaac acaggttttc
       61 ggctgttttc gctccataac acctcctaat tttacccaaa taccccctta atcctccccg
      121 gatacccgat aatcaggcat ccgggttacc ttttaggcgg caacaggcgc acttagcctg
      181 agacctttgc aaatttgtcg gtttcggggt cgtattggta gccttgtgcc tgtatgtctt
      241 ctttgaaagt ttcgtatacg tcatgggcta aaagggcggt tccgacataa ggaactgccc
      301 ttgtacttaa tttcgcgcct aagcgggcaa gtttgctgac ccccgccaat acgccggcgc
      361 gggaaactga tgaagataca accgaactaa ctttacccgt acttgatgct ccagtagata
      421 catgcctaac ttttaaatct tgagcttctg aagttaaata tcttcccgat tctctatcaa
      481 atacaccttt ccaaattctt cttcttttgt catctgaacc tcgaatacct aaatatctgc
      541 catcatcata aacttcaacc ctatcaaatt tacccggaac atttactgat gccaatgcaa
      601 atttaggtac aaaaaaacta aagcatagga taatctttaa aaaatttcgc cctaggataa
      661 gaaacataac attttgcttc atctaattta attaataatg tagaagaatc agggaattga
      721 atttctataa aatctctatc ataacgatga aagaaatttc taaaaatatc aaatgaaaac
      781 gaagatttaa aaaccccttt tctaatcaat tccctataat aaattaacgc ttgtggtaaa
      841 tctctataaa tatgtgaatc agtttgaaat ttaactaaat gatattcaga aataaacata
      901 attcggacct cttaaaatca ctctaaaaat ccgattctac caccgctcaa tccttaaaca
      961 gaaccgcccc gattaatacg ggtacggaaa cgccgagata aaaataaaaa tccatcattt
     1021 caaaaccttt ttcagcaggg aaacaaagta aacggacgcg aggatgccga atactatcca
     1081 gcctgtttca agaccgcttt gcaggttgtc tttcggactg cattccgcca ataaaagcct
     1141 tagcggctga ccgtccgaca tcttccacag gctgccgtta tattccggcc tgacaatctg
     1201 tccgttttct ttgattcttg gtactaccaa gctgaaataa aggttttcag cctggtgctt
     1261 ctcaagacat ttatttccga cttggtagta catgccgtct tacttcatca ctctcttaac
     1321 gatggaaaac acaaaaagcg cggcgaaaat gcccactaca atccaaccgg cttccatacc
     1381 gtcggctttt gcggcttcca aagcgttttt tgctgtatcg ggcaacgttg catttgcatg
     1441 tgcggccaaa gccaggggag cagctgttac aacagccagt tttgcgccgt atttacggca
     1501 ggtgttaata aatttcatga tattttcctt caaaaagtgt ttggcggtaa tggatggaga
     1561 gtttttcaga cgaccgccga acatccgaaa atcagtcttt caaaaatccg aatacgacaa
     1621 attcgtattg gttgccgatt tcttccaaac ctgcgttaat cgcttcttcg aagtcgtaga
     1681 aataatcggc attggtgatt aatttggtat gtccgatgtc gaccgtttca ggagagagat
     1741 acagaaagtc ccctgttgat acggactgga caacatagac tttctgcatt caatcagcct
     1801 ttcttaacgg gttgaaaacc gatgactttc agtttttggg ttttgcccgt agtgacgatt
     1861 tctacgttca ggtttgcttc gatcggaaat tgggcgtttc ggaactgctc gaaattggca
     1921 gagccgccga aatcatattc agtagtagag ctgcccaatg cgttgccttg ggagctgtct
     1981 aagggtgtgg cgacaatcag gc
//
LOCUS       DAXIDM010000180         1992 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000180 DAXIDM010000000
VERSION     DAXIDM010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1992
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.180"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            291..1748
                     /locus_tag="ACFOAE_002018"
     CDS             291..1748
                     /locus_tag="ACFOAE_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012779527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015333 - peptide:proton symporter
                     activity [Evidence IEA];
                     GO_process: GO:0015833 - peptide transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide:H+ symporter"
                     /protein_id="HFC6885422.1"
                     /translation="MSRHPAPTGEKTFFGHPFQLSTLFHIELWERFSFYGMQGILLIY
                     LYYTADKGGLGIDKTLAGGIVGAYSGSVYLSTILGAWFADRVWGAEKTLFLSGIVVML
                     GHIVLAAAPGLYGLLIGLIFIALGSGGVKSTASSMVGALYEQDEMRPLRDAGFSIFYI
                     AINIGGFLGPLLTGLLQENIGFHYGFGAAAVGMAFGLWRYSLGRKNLPHPIVPHPLSK
                     GQGKTAAAVGIALIAALATAIKTGLVNLDNFSGILLSTVILAVIAYFARLLTNPRVSS
                     DNKRHIIAYIPLFLTICMFWAVWFQIYTVATVYFDETVNRTIGSFTVPVAWKDSMQSL
                     WVILFSGLMAAMWTKMGRKQPKTPLKFAMAVFVTGASFLGFVPFISAGTPMPIAVFAL
                     IVLAITIGELMISPIALSISTKIAPPLFKTQMVALNFLAFSLGFTLGGVLFEKGYQAG
                     DEIGFYRLLFYIGAATGFLLLLLVPKLNKMLEGTD"
BASE COUNT          454 a          593 c          454 g          491 t
ORIGIN      
        1 aggcgaggca acgccgtact ggtttaaatt taatccacta taaaaaaccg ccctatcgga
       61 taagccctta acagaaaagg ctttacccgc gccgtatcgg aacacatcct ctaaaataca
      121 atccgttgaa ttgaaaaaaa tataaaaaca tccgcccgcg aaaaacggca gcgcgtcgtt
      181 tgacaaagaa tgaaaatatc ggttaaaaac cgattttcat acaaaaaaca ccgctgccgt
      241 ccgcatccgt ttcagacggt attgagagaa aatcttttag gagaaccttt atgtcccggc
      301 atcccgcccc caccggagaa aaaacattct tcggccaccc cttccagctt tccaccctct
      361 tccatatcga attgtgggaa cgtttttcat tttacggaat gcagggcatc ctgctgattt
      421 acctctacta caccgccgac aaaggcggct tgggcataga caaaaccctc gccggcggca
      481 ttgtcggcgc atacagcggc agcgtgtacc tgtccaccat tttgggggcg tggtttgccg
      541 accgagtatg gggtgcggaa aaaaccctct tcctctcggg catcgtcgtg atgctcggac
      601 acatcgtcct tgccgccgcc ccgggcctgt acggcctttt aatcgggctg atattcatcg
      661 cattgggcag cggcggcgtg aaatctacgg ccagttctat ggtgggcgca ttatacgaac
      721 aggacgaaat gcgcccgctg cgcgatgcgg gattttccat tttctacatc gccatcaata
      781 tcggcggctt cctaggcccg ctgctgaccg gcctgctgca ggaaaacatc ggtttccatt
      841 atggtttcgg cgcggcggcg gtcggtatgg cattcggctt gtggcgttat tccttgggac
      901 gtaaaaacct gccccatccc atcgtccccc atccgctttc aaaaggacag ggcaaaactg
      961 cggccgccgt cggcattgct ctcatcgccg cacttgcaac cgccatcaaa accgggcttg
     1021 tcaacctcga caatttctcc ggcatcctct tatctaccgt catccttgcc gtcattgcct
     1081 attttgcccg cctgctgact aatccccgcg tcagttccga caacaaacgg cacatcatcg
     1141 cctacatccc gcttttcctg accatctgta tgttttgggc cgtctggttt cagatttaca
     1201 ccgtagcaac cgtctatttc gacgaaaccg tcaaccgcac catcggttcg tttaccgtgc
     1261 ccgtcgcctg gaaagattcc atgcaaagcc tgtgggtcat cctgttttcc ggactgatgg
     1321 cggcaatgtg gacaaaaatg gggcgcaaac agcccaaaac cccgctgaaa ttcgctatgg
     1381 cggtatttgt taccggcgcg tcgtttttgg gattcgtccc ctttatttcc gccggcacgc
     1441 cgatgcctat tgcggttttc gcactgatcg tcctcgccat cacgataggc gaactgatga
     1501 tttccccgat tgcgctgtcc atctccacca aaatcgcacc gcctttattc aaaacccaaa
     1561 tggtcgccct taatttcctt gccttttcat taggcttcac tttgggcggc gtattgtttg
     1621 aaaaaggcta tcaggcgggc gacgaaatcg gcttctaccg gctgctgttc tacatcggcg
     1681 cagccacagg cttcctgctg ctcctgctcg tccccaaatt gaacaaaatg ctcgaaggca
     1741 cagactaagt cccgccccga tgccgtctaa acccttcaga cggcattttt ccgcataatg
     1801 aaaccaaacc gtttccaccc gacaggacag gctccccccc aaccggaagg cagcctgccg
     1861 attgtcattt aaatatctga ctgattccgt ctgtttgcaa gggaaatagc cgtttatttc
     1921 cgcttgggcg gaaaccggtt ctattgagta aaaggcattt tatccgacta aattagtgct
     1981 gcatcaacgg aa
//
LOCUS       DAXIDM010000181         1945 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000181 DAXIDM010000000
VERSION     DAXIDM010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1945
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.181"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            79..1248
                     /gene="metZ"
                     /locus_tag="ACFOAE_002019"
     CDS             79..1248
                     /gene="metZ"
                     /locus_tag="ACFOAE_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-succinylhomoserine sulfhydrylase"
                     /protein_id="HFC6885423.1"
                     /translation="MSKKLHPQTLAIRGGKEQTEYREHNQALFLTSSFMWDNAQHAAD
                     LFSKKIKGFTYTRTANPTTAAFEKRIAALEGAERAVATSTGMSAIQAAFFTFLQAGDH
                     VISSRSLFGTTVGFINNIVTKFGIEVSHVSPTDINEWKAAVKANTKLLFLETPSNPLG
                     EVADLEALAELAHGIGALLVVDNSLLSPVGSQPLKHGADISVSSATKAIDGHGRVMGG
                     VLAGSEELMAQAAVYCNSCGLAMSPFNAWQLLSGVETLSLRMEKQFDNALKIAQWLQA
                     QPQVQAVYYTGLPDHPQAELIRKQQNGGGIVIGFEVADQAAAWKVVDGVELFSRTANL
                     GDVRSTITHPWTTTHGRMQPEEKLAANIRPGLVRLSVGLEYVGDLVDDLKQALAR"
     gene            1335..1541
                     /locus_tag="ACFOAE_002020"
     CDS             1335..1541
                     /locus_tag="ACFOAE_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2788 domain-containing protein"
                     /protein_id="HFC6885424.1"
                     /translation="MDEAVFADWALKICLTGLIIFLGFIVWNLGKESKAGKFGIAILF
                     LVLGLGVFGFVFKELLIKFLVLPK"
     gene            complement(1640..1752)
                     /locus_tag="ACFOAE_002021"
                     /pseudo
     CDS             complement(1640..1752)
                     /locus_tag="ACFOAE_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014582428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT          474 a          501 c          502 g          468 t
ORIGIN      
        1 ggtttaaatt taatccacta taaattaaac aacgggcgca cgctccgttg ccgaacggat
       61 aaaaccgagg aatcaccgat gagcaaaaaa ctccatccgc aaacgctcgc catacgcggc
      121 ggcaaagaac aaaccgaata ccgcgaacac aatcaggcat tgttcctgac cagcagcttc
      181 atgtgggaca acgcccaaca cgctgccgat ttgttttcaa aaaaaatcaa aggcttcact
      241 tatacccgta ccgccaaccc gaccacagcc gcctttgaaa aacgcatcgc cgctttggaa
      301 ggtgcggaac gcgcggtcgc cacttcgacc ggcatgtccg cgattcaggc ggcgtttttc
      361 acctttttgc aggcgggcga ccatgtgatt tccagccgca gcctgttcgg cacgaccgtc
      421 ggctttatca ataacatcgt taccaaattc ggcatcgaag tgagtcacgt gtcgccgact
      481 gatataaacg aatggaaagc cgccgtcaaa gccaacacca aactgctgtt tttggaaacg
      541 ccgtccaatc ccttgggaga agtggccgac ttggaagcct tggcggaatt ggcgcacggc
      601 atcggcgcgc tcttggtggt ggacaacagc ctgctgtcgc ctgtcggctc tcagcctttg
      661 aaacacggcg cggatatttc cgtttcctcc gcgaccaaag ccatagacgg acacgggcgc
      721 gtgatgggcg gcgtgttggc gggttcggaa gaactgatgg cgcaggccgc cgtttactgc
      781 aactcttgcg ggctggcgat gtcgccgttt aacgcgtggc agttgttgag cggcgtggaa
      841 accctgtcgc tgcgtatgga aaaacagttc gacaacgccc tgaaaatcgc acaatggctg
      901 caagcgcagc cgcaggttca agccgtgtac tacactggat tgcccgacca tccgcaggcg
      961 gagcttatcc gcaaacagca aaacggcggc ggcatcgtca tcggctttga agtcgccgac
     1021 caagcagccg cgtggaaagt cgtggacggc gtggaactct tttcccgtac cgccaacctc
     1081 ggcgacgtgc gctcgaccat cacccatccg tggacaacca cgcacggcag gatgcagccc
     1141 gaagaaaaac tcgccgccaa catccgcccc ggattggtgc gcctgtcggt cggtttggaa
     1201 tatgttggcg acctcgtcga tgatttgaaa caggcgctcg cgcgctgatt gcgtgtttca
     1261 gacggcattg gacagcagat gccgtctaaa acccttatct tatatgacat acacgtcaac
     1321 aataggaaaa aaatatggat gaagcggttt ttgccgattg ggcgttgaaa atctgcctga
     1381 ccggcttgat tatttttttg ggttttatcg tttggaattt gggcaaggag tctaaagcgg
     1441 gcaaattcgg catcgccatt ttgtttttgg ttttgggctt gggcgtgttt ggttttgtgt
     1501 tcaaagagtt attgattaag tttttggtat tgccgaaata ggtttgcggt ctgtcaaaat
     1561 gccgtctgaa atcataaaaa gtaatctgca ccctaaaagt ttgatttaac cgccaactga
     1621 ttaaggtgcg gatttttatg acaaaatata gtggattaac aaaaaccagt acggcgttgc
     1681 ctcgccttgc cgtactattt gtactgtctg cggcttcgtc gccttgtctt gatttaaatt
     1741 taatccacta taaaaatcat ctttccgcag tcattcccac ggatgcgaaa gcctgtcttt
     1801 ttgaatcccg gataatttta catcgtcatt cccgcgcagg tgggaatcca gatcattggg
     1861 tagcggcaat gttcaaaagt cgtctgaaaa atcagaagtt ctagattccc gtttttacgg
     1921 gaatgacgga atttcagacg gcatc
//
LOCUS       DAXIDM010000182         1912 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000182 DAXIDM010000000
VERSION     DAXIDM010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.182"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..209
                     /locus_tag="ACFOAE_002022"
     CDS             <1..209
                     /locus_tag="ACFOAE_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885425.1"
                     /translation="LIVATPLDSSQGNALGSSTTEYDFGGSANFEQFRNAQFPIEANL
                     NVEIVTTGKTQKLKVIGFQLVKKG"
     gene            214..411
                     /locus_tag="ACFOAE_002023"
     CDS             214..411
                     /locus_tag="ACFOAE_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885426.1"
                     /translation="MQKVYVVQSVSTGDFLYLSPETGDIGHTKLITNADYFYDFEEAI
                     NAGLEEIGNQYEFVVFGFLKD"
     gene            485..703
                     /locus_tag="ACFOAE_002024"
     CDS             485..703
                     /locus_tag="ACFOAE_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002236731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HFC6885427.1"
                     /translation="MKFINTCRKYGAKLAVVTAAPLALAAHANATLPDTAKNALEAAK
                     ADGMEVGWIVVGVFAALFVFSIVKRVMK"
     gene            710..988
                     /locus_tag="ACFOAE_002025"
     CDS             710..988
                     /locus_tag="ACFOAE_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002223477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885428.1"
                     /translation="MYYQVGNKCLEKHQAENLYFSLVVPRIKENGQIVRPEYNGSLWK
                     MSDGQPLRLLLAECSPKDNLQSGLETGWIVFGILASVYFVSLLKKVLK"
     gene            1116..1433
                     /locus_tag="ACFOAE_002026"
     CDS             1116..1433
                     /locus_tag="ACFOAE_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1132 family protein"
                     /protein_id="HFC6885429.1"
                     /translation="MNKPFITQAQLALYKYQPSSKYFGQSMAVIAQSEFVEFAKINKS
                     ENVIDCFSFFWNRRIKHDIWLISFSDNSEMVIKESLKDGHKIYKFEFCKIVDNCNFDD
                     VFV"
     gene            1417..1812
                     /locus_tag="ACFOAE_002027"
     CDS             1417..1812
                     /locus_tag="ACFOAE_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IgG-binding virulence factor TspB family
                     protein"
                     /protein_id="HFC6885430.1"
                     /translation="MMYSFEANANAVKISETVSVDTGQGAKIHKFVPKNSKTYSSDLI
                     KTVDLTHIPTGAKARINAKITASVSRAGVLAGGGKLARLGAKFSTRAVPYVGTALLAH
                     DVYETFKEDIQARGYQYDPETDKFAKVSG"
BASE COUNT          569 a          395 c          440 g          508 t
ORIGIN      
        1 acctgattgt cgccacaccc ttagacagct cccaaggcaa cgcattgggc agctctacta
       61 ctgaatacga tttcggcggc tctgccaatt tcgagcagtt ccgaaacgcc caatttccca
      121 tcgaagcaaa cctgaacgtg gaaatcgtta ctacgggcaa aacccaaaaa ctgaaagtca
      181 tcggttttca actcgtgaag aaaggctgat tgaatgcaga aagtctatgt tgtccagtcc
      241 gtatcaacag gggactttct gtatctctct cctgaaacgg gcgacatcgg acataccaaa
      301 ttaatcacca atgccgatta tttctacgac ttcgaagaag cgattaacgc aggtttggaa
      361 gaaatcggca accaatacga atttgtcgta ttcggatttt tgaaagactg attttcggat
      421 gttcggcggt cgtttgaaaa acgctccatc cattaccgcc aaacactttt tgaaggaaaa
      481 tatcatgaaa tttattaaca cctgccgtaa atacggcgca aaactggctg ttgtaacagc
      541 tgctcccctg gctttggccg cacatgcaaa tgcaacgttg cccgatacgg caaaaaacgc
      601 tttggaagcc gcaaaagccg acggtatgga agtcggttgg attgtagtgg gcgttttcgc
      661 cgcgcttttt gtgttttcca tcgttaagag agtgatgaag taagacggca tgtactacca
      721 agtcggaaat aaatgtcttg agaagcacca ggctgaaaac ctttatttca gcttggtagt
      781 accaagaatc aaagaaaacg gacagattgt cagaccggaa tataacggca gtctgtggaa
      841 gatgtcggac ggtcagccgc taaggctttt attggcggaa tgcagtccga aagacaacct
      901 gcaaagcggt cttgaaacag gctggatagt attcggcatc ctcgcgtccg tttactttgt
      961 ttccctgctg aaaaaggttt tgaaatgatg gatttttatt tttatctcgg cgtttccgta
     1021 cccgtattaa tcggggcggt tctgtttaag aattgagcgc atgaagttat ggtgtcaaaa
     1081 tcaggctttc aaaacaatca ttgaaaggca gaaccatgaa caagccgttt atcactcagg
     1141 cgcagttggc actttataaa tatcagccgt ctagcaagta ttttgggcaa tcgatggcgg
     1201 ttatagcgca atctgaattt gttgaatttg cgaagattaa taagtctgaa aatgttattg
     1261 attgtttctc ttttttctgg aatagaagaa ttaaacatga tatttggcta atctcatttt
     1321 ctgataattc agaaatggta attaaagaat ccctgaaaga tggtcataaa atatacaaat
     1381 ttgaattttg caaaattgtc gataattgca attttgatga tgtattcgtt tgaagcgaat
     1441 gcaaatgcag taaaaatatc tgaaactgtt tcagttgata ccggacaagg tgcgaaaatt
     1501 cataagtttg tacctaaaaa tagtaaaact tattcatctg atttaataaa aacggtagat
     1561 ttaacacaca tccctacggg cgcaaaagcc cgaatcaacg ccaaaataac cgccagcgtt
     1621 tcccgcgccg gcgtattggc ggggggcggc aaacttgccc gcttaggcgc gaaattcagc
     1681 acaagggcgg ttccctatgt cggaacagcc cttttagccc atgacgtata cgaaactttc
     1741 aaagaagaca tacaggcacg aggctaccaa tacgaccccg aaaccgacaa atttgcaaag
     1801 gtctcaggct aagtgcgcct gttgccgcct aaaaggtaac ccggatgcct gattatcggg
     1861 tatccgggga ggattaaggg ggtatttggg taaaattagg aggtatttgg gg
//
LOCUS       DAXIDM010000183         1893 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000183 DAXIDM010000000
VERSION     DAXIDM010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1893
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.183"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..645
                     /locus_tag="ACFOAE_002028"
     CDS             <1..645
                     /locus_tag="ACFOAE_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC6885431.1"
                     /translation="KLINCQLTEKNLKVEKASASVVDATIIQTAGSKQRQAIEVDEEG
                     QISGQTTPSKDSDARWIKKNGLYKLGYKQHTRTDAEGYIEKLHITPANAHECKHLSPL
                     LEGLPEGTTVYADKGYDSAENRQHLEEHQLLDGIMSKACRNRPLAETQTKRNRYLSKP
                     RYVVEQSFGTLHRKFRYARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPAAA"
     gene            complement(856..1893)
                     /locus_tag="ACFOAE_002029"
                     /pseudo
     CDS             complement(856..1893)
                     /locus_tag="ACFOAE_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
BASE COUNT          403 a          509 c          517 g          464 t
ORIGIN      
        1 aaactgatta actgccaact gaccgaaaaa aacctaaaag tagagaaagc atccgcctcc
       61 gtcgttgacg ccaccattat tcagaccgct ggcagcaaac agcgtcaggc catagaagtt
      121 gacgaagaag gacaaatcag cggccaaacc acaccgagta aggacagcga tgcccgttgg
      181 atcaagaaaa acggcctcta caaactcggt tacaaacaac atacccgtac cgatgcggaa
      241 ggctatatcg agaaactgca catcaccccc gccaatgccc atgagtgcaa acacctgtcg
      301 ccgttgttgg aagggttacc cgaaggtacg accgtctatg ccgataaagg ctatgacagt
      361 gcggaaaacc ggcaacatct ggaagaacat cagttgttgg acggcattat gagcaaagcc
      421 tgccgcaacc gtccgctggc ggaaacgcaa accaaacgta accgatattt gtcgaagccc
      481 cgttatgtgg tcgaacaaag cttcggtacg ctgcaccgta aattccgcta cgctcgggca
      541 gcctatttcg gactgattaa agtgagtgcg caaagccacc tgaaggcgat gtgtttgaac
      601 ctgttgaaag cggccaacag gctaagtgcg cccgctgccg cctaaaaggc agcctggatg
      661 cctgattatc gggtatccgg ggaggattaa gggggtattt gggtaaaatt aggcggtatt
      721 tggggcgaaa acagctgaaa acagctgaaa acctgtgttg gggtttcggc tgtcgggagg
      781 gaaaggaatt ttgcaaaggt ctcaacaagt tttaccggaa aggcattttg tcaatttatc
      841 cattctttcc ttgctaagcg cattactctc taccgccaca gcagccgcat tcgccgcagc
      901 attcacatcc cccttgctca acgccgcaac cgtccctgct gccagcttcg ccttagcaat
      961 gatttttgcc cggtctttca cattcaagct gccagggtct ctgccgtcca gtagggtttc
     1021 gccaaggatt tcaccgaccg ccgcgccgat tgcgccgtcc cgacatttgc ctttatttgc
     1081 taccgctgcc gcacagcccg ctatggcatg ggcaatcttg tgggcaatgt agtcttcgct
     1141 gagattaaat ttgattttgc tcgctacttc tccgtgtacg gtactgacta tcgcacccag
     1201 tgcggcatcg cccaagttgt ctttcaggct gccgccgttg atggcggtat ggacacttgc
     1261 ggcagcggtg ctgttgatca ggttagcggt cagtttgcct gctgcgggac tgtgaaaatg
     1321 tttgctgacg gcttcggctg cttgggtgtt cagcccgctt atgccctgca gtacgcctgc
     1381 ggttacggcg gcggtggcgg cctgtctgac ggtgctgctt ttgcccagtt ctttcagggt
     1441 atggtttatg tctcctttgt tgttgatgag ggaaactgcg gcttggctgg cgagactggc
     1501 cagtgcggct ttgcctgcgg ctgtggtgat agctgcagct gatgtgcctg ctgctactcc
     1561 ggttgtggct gccgttcctg ctgctactcc agttccggct gccgttcctg ctgcggctcc
     1621 tcccgctcct gcgcctgccg cgcccgccgt tccggcggct gccggggcgg acagtgcacc
     1681 gtaggtcaat acggttacga cgataacgac gacagctgct gctgcgggtg tcatgccctc
     1741 ctgtttgtag tcccatttat cgtaagcaag ctgcacctga ttccagttga tgtttttcgc
     1801 aacttgaagt tgtttcaaat aagcatactc gggctgcttg gtgagggttt cgatttgggt
     1861 tttcagattg cctttgggaa tatcgacaat gta
//
LOCUS       DAXIDM010000184         1886 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000184 DAXIDM010000000
VERSION     DAXIDM010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1886
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.184"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(106..543)
                     /gene="rnhA"
                     /locus_tag="ACFOAE_002030"
     CDS             complement(106..543)
                     /gene="rnhA"
                     /locus_tag="ACFOAE_002030"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003689763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HFC6885432.1"
                     /translation="MNQTVYLYTDGACKGNPGAGGWGVLMRYGSHEKELFGGEAQTTN
                     NRMELTAVIEGLKSLKRRCTVIICTDSQYVKNGMENWIHGWKRNGWKTAAKQPVKNDD
                     LWKELDALVGRHQVSWTWVKGHAGHAENERADDLANRGAAQFS"
     gene            657..1046
                     /locus_tag="ACFOAE_002031"
                     /pseudo
     CDS             657..1046
                     /locus_tag="ACFOAE_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216748.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
     gene            complement(1196..>1886)
                     /locus_tag="ACFOAE_002032"
     CDS             complement(1196..>1886)
                     /locus_tag="ACFOAE_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HFC6885433.1"
                     /translation="YRNWLAQDNTLSELLKLINRQLTEKGLKIEKASAAVVDATIIQT
                     AGSTQRQVIEVDEEGQINGQTTPSKDSDARWIKKNGLYKLGYKQHTRTDAEGYIEKLH
                     ITPANAHECKHLSPLLEGLPKGTTVYADKGYDSKENRQHLKEHQLLDGIMRKACRNRP
                     LSETQTKRNRYLSKTRYVVEQSFGTLHRKFRYARAAYFGLLKVSAQSHLKAMCLNLLK
                     AANRLSAPAAA"
BASE COUNT          345 a          466 c          552 g          523 t
ORIGIN      
        1 gttgcccgac ggtttggatt cccgcctgcg tgggaatgac ggtggaggac gatgccgtct
       61 aaagcccatt agcggtttca gacggtattt ttgtcggtgc ggcagtcagg aaaactgcgc
      121 cgcgccacgg tttgccaaat cgtcggcgcg ttcgttttcc gcgtgtcccg cgtgtccttt
      181 cacccaagtc cagctgactt ggtgccgtcc gaccagcgcg tcgagttctt tccacaagtc
      241 gtcgtttttg acgggctgtt tggcggcggt tttccagccg ttgcgcttcc aaccgtgtat
      301 ccagttttcc atgccgtttt tgacgtattg cgagtcggtg cagatgatga cggtgcagcg
      361 gcgtttgagc gatttcagtc cttcgatgac ggcggtcagt tccatacggt tgttggtggt
      421 ttgcgcttcg ccgccgaaaa gttctttttc gtggctgccg tagcgcatta atacgcccca
      481 gccgcccgcg ccgggattgc ctttgcacgc gccgtcggtg taaaggtaaa cggtttggtt
      541 cattattgtg cctttatgtg gtgtccggcg tgattataag cggtttgtgc gccgtgccgt
      601 ctgaaagatt gcggcggatt aaaataggca tataatgtgc aactttattt ttgaatatga
      661 aggagcggat agtgggtcaa agcggcgagt tgttttgttt cggacaaatg cccgtatgga
      721 aggcggaaaa cctgccggaa attttgttgt cgggttattc gtccgaagga ggggaatggg
      781 tctgcctgaa tgtgttgcag ggcgatgtcg aagtccgcac gcaggacggg gcggcagagg
      841 tttggtcggc ggaaagcggc gattgcgtgt ttgcgccgca gcaggtgttt tcggtcaaac
      901 tgaaaacgga cgatgccgaa atccgtttgt cgctgtattg cgcggcggca gactattttc
      961 acaaaaaata cgggatgagt gccacgcatt ctgcggtcgc ggcggcacgg gataccgtac
     1021 cggcgggcag ggcgttggat atgggttgag acctttgcaa aattcctttc cctcccgaca
     1081 gccgaaaccc aaacacaggt tttcggctgt tttcgcccca aatacctcct aattttaccc
     1141 aaataccccc ttaatcctcc ccggataccc gataatcagg catccgtgct gccttttagg
     1201 cggcagcggg cgcacttagc ctgttggcgg ctttcaacag gttcaaacac atcgctttca
     1261 gatggctttg cgcactcact ttgagcagcc cgaaataggc tgcccgcgca tagcggaatt
     1321 tacggtgcag cgtaccgaag ctctgttcaa ccacataacg agtcttcgac aaataccggt
     1381 tgcgtttggt ttgcgtttcc gacagcggac ggttgcggca ggctttgcgc ataatgccgt
     1441 ccagtaactg atgttctttc agatgctgcc ggttttcctt actgtcgtag cctttgtcgg
     1501 catagacggt cgtacctttg ggcagtcctt ccaacaacgg cgacaggtgt ttgcactcat
     1561 gggcattggc gggggtaatg tgcagtttct cgatatagcc ttccgcatcg gtacgggtat
     1621 gttgtttgta accgagtttg tagaggccgt ttttcttgat ccaacgggca tcgctgtcct
     1681 tactcggtgt ggtttggccg ttgatttgtc cttcttcatc gacttctatg acctgacgct
     1741 gtgtgctgcc ggcggtctga ataatggtgg catcaacgac ggcggcggat gctttctcta
     1801 tttttaagcc tttttcggtc agttgtcggt taatcagttt gagcaattcg gacagggtat
     1861 tatcttgcgc cagccagttg cggtag
//
LOCUS       DAXIDM010000185         1866 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000185 DAXIDM010000000
VERSION     DAXIDM010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.185"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..512)
                     /locus_tag="ACFOAE_002033"
     CDS             complement(<1..512)
                     /locus_tag="ACFOAE_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer family protein"
                     /protein_id="HFC6885434.1"
                     /translation="MNVQKSTRFIGIKVGKSNYSKNELNETKLPVRVIAQTAKTRSGW
                     DTVLEGTEFKTTLSGADIQAGVGEKARADAKIILKGIVNRIQTEEKLESNSTVWQKQA
                     GSGSTVETLKLPSFEGPALPKLTAPGGYIADIPKGNLKTEIEKLAKQPEYAYLKQLQT
                     VKDVNWNQVQL"
     gene            complement(658..921)
                     /locus_tag="ACFOAE_002034"
     CDS             complement(658..921)
                     /locus_tag="ACFOAE_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002234239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885435.1"
                     /translation="MDKEIKICPRCEQGYLYHAKPKYFSGEVILCDECYAMWLGDMKI
                     FYGQYGKDFYDYHEFMKDKGIEEINMWEGELFDHPYYEDEKFK"
     gene            complement(940..>1866)
                     /locus_tag="ACFOAE_002035"
     CDS             complement(940..>1866)
                     /locus_tag="ACFOAE_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HFC6885436.1"
                     /translation="NTAHGEAASKIKQLDQHYITHKIAHAIAGCAAAAANKGKCQDGA
                     IGAVVGEIVGEALVKNTDFSGMTASEIEKAKANITAYAKLVAGATVGVTGGNVDVAAN
                     ASETAVKNNALDIIWDIGNLVWDGGKWIYAKSIGDKQMAREAAIDFGVDAAAAAVPFV
                     PAGATKISRGGAYVLKAGDEAVDTAKAIQEIQKQTGIKLTYDKVNKVWTTPAGLDYGL
                     DAKHGNRIKHVLAHTIPNPNKPVHSVFNVSRKEVLPLVDEAWRMKGNPLPNDSSVYLV
                     DMKKPIGTKGETKVRIVVQKGTNKIISAYPQK"
BASE COUNT          441 a          461 c          370 g          594 t
ORIGIN      
        1 agctgtactt ggttccagtt cacgtccttg accgtctgaa gctgtttcag ataggcatat
       61 tcgggctgtt tggccagctt ttcgatttcg gttttgaggt tgcctttggg gatgtcggcg
      121 atatagccgc cgggagcggt cagcttaggc agtgccggcc cttcaaagct cggtagcttc
      181 agcgtttcaa ccgtgctgcc gcttccggcc tgcttttgcc atacggtcga gttggattcc
      241 agcttttctt cggtttggat gcggttaacg atgcctttta ggataatttt cgcatcggct
      301 cgggcttttt cacccacccc tgcctgtatg tcggctccgg aaagggtggt tttgaattcg
      361 gtgccttcga gtacggtatc ccagccggaa cgggttttgg ctgtttgggc gataacgcgt
      421 acgggcagtt tggtttcgtt cagctcgttt ttgctgtaat tgcttttacc cactttgatg
      481 ccgatgaaac gggtactttt ctgaacattc aattggtgtt ggtgaatgcc ttcggctgcc
      541 agcagttgca ttgaggccgt ctgaaaaacg gatattcaga cggcctattg ctactttaaa
      601 taatatttgg gtttaaaata tcatcgtatt tcccaaattc ggggaacaga aaatcaatta
      661 tttaaatttt tcatcctcat aatatgggtg atcaaaaagc tctccttccc acatatttat
      721 ttcttctatg cctttatctt tcataaactc atgataatca taaaaatctt ttccatattg
      781 tccgtaaaaa attttcatat ccccaagcca catagcataa cattcatcgc ataaaatgac
      841 ctccccagag aaatatttag gctttgcatg ataaaggtag ccttgctcac atcttgggca
      901 aattttaatt tctttatcca taagagattc ctttcttaat tatttctgag gatatgcaga
      961 aatgatttta tttgttcctt tttgcacaac aatccgcact tttgtttctc cttttgttcc
     1021 aataggtttc ttcatatcta caagatatac ggatgaatca tttggcaaag gatttccttt
     1081 cattctccaa gcttcatcaa ccaaaggcaa aacttcttta cgggacacat taaaaacaga
     1141 atgaacaggt ttgtttggat ttggaattgt atgggctaaa acatgtttaa tcctattacc
     1201 atgcttagca tctaacccat aatctaaccc cgccggtgtt gtccaaacct tattaacctt
     1261 atcataagta agcttgattc cggtctgctt ctgaatttcc tgtatggctt tagccgtatc
     1321 aactgcttcg tctcccgcct tcagaacata agccccgcct cggctgattt tagtcgcacc
     1381 tgccggaaca aagggaacgg cagctgcggc ggcatccaca ccaaaatcaa tcgccgcttc
     1441 tcgagccatc tgcttatcgc caatagattt ggcgtaaatc catttaccgc cgtcccatac
     1501 gaggttgccg atatcccaaa taatatctaa tgcattattt ttaacagctg tttcggaagc
     1561 atttgccgcc acatcaacat tgcctcctgt aacacctaca gtcgctccgg ctaccaattt
     1621 tgcatacgca gtaatattcg ctttagcttt ttcaatttca gaagcagtca taccgctgaa
     1681 atcggtattc ttaaccaaag cctccccgac aatctccccc acgaccgcac caatcgcgcc
     1741 gtcctgacac ttgcccttat tcgccgccgc agccgcacag cccgctatgg catgggcaat
     1801 cttgtgggta atgtagtgct gatccaactg tttgatttta ctggctgctt ctccatgcgc
     1861 agtatt
//
LOCUS       DAXIDM010000186         1863 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000186 DAXIDM010000000
VERSION     DAXIDM010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.186"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..104)
                     /locus_tag="ACFOAE_002036"
     CDS             complement(<1..104)
                     /locus_tag="ACFOAE_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC6885437.1"
                     /translation="MSTFFRQTAQAMIAKHIDRFPLLKLDQVIDWQPI"
     gene            145..963
                     /locus_tag="ACFOAE_002037"
     CDS             145..963
                     /locus_tag="ACFOAE_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002238820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin"
                     /protein_id="HFC6885438.1"
                     /translation="MGNFAKVSCSTTMEKVNAIKKDEQFSKVIDTEIQKVCSRNPLGD
                     GCRNGINMSIKYIAMPAAWKYMPTDVSRVAKEVFGYLYNSQGASTRFDKYFNTIDNRA
                     DFFAASNLYEQNLGSKARWFGGADFVSRAAITGLGADGEASYITFAAGKVVGNPPIYE
                     WRAASGNALIVNGFYNFRDLFNKKTNPREWDIQQLKSEQKLLQPIHQKYLSNEKDYLS
                     LIKGVTSNKIFSIIPNPLDERKKIEDGINMLDYKSRIKYGCKLMGYSEKQGCKP"
     gene            960..1394
                     /locus_tag="ACFOAE_002038"
     CDS             960..1394
                     /locus_tag="ACFOAE_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885439.1"
                     /translation="MNKNYLFYLIQNIKSIFLIGGVFFGLLIFSGLWGNDFKLSFLGV
                     IDFIFGMVGGGFIVMLWFLIPVILSTLFRWVFQNQLAVSVILTFIVFYTYGYFSLFNS
                     SERVGSFWYLVIPTIMFIGLSEWFIYKSSVHSLGENVTPRSN"
     gene            complement(1462..1730)
                     /locus_tag="ACFOAE_002039"
                     /pseudo
     CDS             complement(1462..1730)
                     /locus_tag="ACFOAE_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002244123.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          555 a          276 c          417 g          615 t
ORIGIN      
        1 tcgatcggct gccaatcaat cacctggtcc aacttcaata gcgggaagcg gtcgatgtgt
       61 ttggcaatca tggcttgggc ggtttgccgg aagaaggtgc tcatgagaaa tcccctaaat
      121 gtcttggtgg gaatttaggg gattttgggg aattttgcaa aggtctcttg ttctactacg
      181 atggaaaaag taaatgccat caaaaaggat gaacaattta gcaaagtaat tgatacggaa
      241 attcaaaaag tctgttctag gaacccattg ggcgatggtt gcagaaacgg cattaatatg
      301 tctattaaat atattgccat gcctgctgcg tggaagtata tgcctacgga tgtatcacgg
      361 gttgccaaag aagtttttgg ctatttatat aactcacaag gggcatctac aagatttgac
      421 aagtatttca acaccattga caatcgtgca gatttctttg ctgccagcaa tctttatgag
      481 caaaatttgg gttcaaaagc acgatggttt ggtggagctg attttgtatc gcgtgctgct
      541 ataactgggt taggggcaga cggagaagct tcttatataa cttttgcggc aggtaaagtt
      601 gttggtaatc ctccaattta tgaatggagg gctgcgtcag gcaatgcact gatagtaaat
      661 ggattttata attttagaga cttgttcaat aaaaaaacta atcctaggga gtgggatatt
      721 caacagttga aaagcgagca aaagttatta cagcctattc accaaaaata tttgagtaat
      781 gagaaggatt atttgtcatt gattaaaggg gtaacatcaa ataagatatt ttcaataatt
      841 ccaaatcctt tagatgagag gaaaaaaata gaggatggaa ttaatatgtt agattacaaa
      901 tctagaatta aatatggttg taagcttatg ggatattctg agaaacaggg atgcaagcca
      961 tgaataaaaa ttatttattt tatcttattc aaaatattaa atctattttc ttaataggtg
     1021 gagtattttt tggcctttta attttttcag gtttatgggg taatgatttt aaactatctt
     1081 ttttaggggt aatagatttt atatttggga tggtaggggg tgggtttata gttatgttat
     1141 ggtttctaat tccagtgata ttatcaactt tattcagatg ggtatttcaa aatcaacttg
     1201 ctgtatctgt catattaacc ttcattgttt tttatacata tgggtacttt tctttattta
     1261 attcatctga aagagtcggt agtttttggt atttggtaat cccaaccata atgtttattg
     1321 gactgtctga atggtttatc tataaatcta gcgtgcatag tttaggtgaa aatgtaactc
     1381 cacgttccaa ttgaagaaaa agattgtctg aaaactaaat ttaatttcag atgaccttag
     1441 attcggattt caagtacaac actagggtat cgatggttgg aacagattca agaataaaac
     1501 acttggcgtt tcgtagccaa gtgtttttct cggtcggtgg ttcaactcat cttgaaccct
     1561 acgtatctcc cgatcgctga tgtttcggaa aacggtttgt ttggggaata ttgtcggatg
     1621 agtccattgg tgttttcatt cagccctttc tcccaagaat ggtaagggcg gtaaaaatag
     1681 gtttccgcct tcaatgtttt ggccatttgg atgtgtcggt agaatgcttt gattaaacaa
     1741 gttgcaaata gcttacctga tggtagtcct gctaaagctg ctgtcttcaa agcggagcgg
     1801 gaaggcaaat taaaaacggc aatagcaggc gttgatcgtc aaacaggtaa ggccgttatt
     1861 ctt
//
LOCUS       DAXIDM010000187         1858 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000187 DAXIDM010000000
VERSION     DAXIDM010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1858
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.187"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..791)
                     /gene="rfbA"
                     /locus_tag="ACFOAE_002040"
     CDS             complement(<1..791)
                     /gene="rfbA"
                     /locus_tag="ACFOAE_002040"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002221803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFC6885440.1"
                     /translation="MKGIILAGGSGTRLYPITRGVSKQLLPVYDKPMIYYPLSVLMLA
                     GIRDILVITAPEDNASFKRLLGDGSDFGISISYAVQPSPDGLAQAFIIGEEFIGNDNV
                     CLVLGDNIFYGQSFTQTLKQAAAQTHGATVFAYQVKNPERFGVVEFNENFRAVSIEEK
                     PQRPKSDWAVTGLYFYDNRAVEFAKQIKPSARGELEITDLNRMYLEDGSLSVQILGRG
                     FAWLDTGTHESLHEAASFVQTVQNIQNLHIACLEEIAWRNGWLSD"
     gene            complement(854..>1858)
                     /gene="rfbB"
                     /locus_tag="ACFOAE_002041"
     CDS             complement(854..>1858)
                     /gene="rfbB"
                     /locus_tag="ACFOAE_002041"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002220121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFC6885441.1"
                     /translation="IRNTQDSVVNLDKLTYAGNLESLTDIADNPRYAFEQVDICDRAE
                     LDRVFAQHRPDAVMHLAAESHVDRSIGSAGEFIQTNIVGTFNLLEAARAYWQQMPSEQ
                     HEAFRFHHISTDEVYGDLGGTDDLFTETAPYAPSSPYSASKASSDHLVRAWLRTYGLP
                     TIVTNCSNNYGLYHFPEKLIPLMILNALDGKPLPVYGDGMQIRDWLFVEDHARALYQV
                     VTEGVVGETYNIGGHNEKANIEVVKTICALLEELAPEKPAGVARYEDLITFVQDRPGH
                     DVRYAVDAAKIRRDLGWLPLETFESGLRKTVQWYLDNKTWWQNVLNGSYRLERLGTGK
                     "
BASE COUNT          401 a          459 c          542 g          456 t
ORIGIN      
        1 tcatcggaaa gccaaccgtt gcgccaagcg atttcttcca ggcaggcgat gtgcaggttt
       61 tggatgtttt gcacggtttg gacgaacgaa gccgcctcgt gcaggctttc gtgcgtaccg
      121 gtgtccagcc acgcgaaacc gcgtcccaat atttgaacgg agagcgagcc gtcttccaaa
      181 tacatccggt tgaggtcggt aatttccaat tcgccgcgtg cggacggttt gatttgtttg
      241 gcgaactcga cggcacggtt gtcgtagaag tacaagccgg ttaccgccca atcggatttg
      301 ggccgttgcg gtttttcttc gatggaaacg gcgcggaagt tttcgttaaa ttcaaccacg
      361 ccgaaacgtt cggggttttt gacctgataa gcaaacacgg ttgcgccgtg cgtttgcgct
      421 gccgcctgtt tcaatgtttg cgtaaacgac tgaccgtaaa aaatattgtc gcccaaaacc
      481 aagcaaacat tgtcgttgcc gataaattct tcgccgatga taaatgcctg tgccaagccg
      541 tccggactgg gttgcacggc ataactgatg gaaatgccga aatcgctgcc gtcgccaagc
      601 aggcgtttga aagaggcgtt gtcttcaggc gcggtaatca ccaaaatatc gcggattccc
      661 gccagcatca aaaccgacaa ggggtaataa atcatcggtt tgtcgtacac gggcaggagc
      721 tgtttggata cgccgcgcgt gatggggtag aggcgcgtgc cgctgccgcc tgccagtatg
      781 atgcctttca tcttttcttt cttcctttgc gatgggtttt cagacggcat tgcgtcggga
      841 tgccgtctga aaactatttt ccagtaccta aacgttccaa acgatagctg ccgttcaata
      901 cattttgcca ccaggttttg ttgtccagat accattgcac ggttttgcgg aggccggact
      961 cgaaggtttc caaaggcagc cagcccaaat cccgcctgat tttggctgcg tcgacggcgt
     1021 agcgtacgtc atggccgggg cggtcttgta cgaaagtaat caaatcttca taacgcgcca
     1081 caccggccgg tttttcggga gcgagttctt ccagcagggc gcagatggtt ttgacgactt
     1141 caatattggc tttttcattg tggccgccga tattgtaggt ttcgccgaca acaccttcgg
     1201 taacaacctg atacagtgcg cgcgcgtggt cttcgacaaa cagccagtcg cggatttgca
     1261 taccgtcgcc gtacacaggc agcggtttgc cgtcaagcgc gttcagaatc atcaaaggaa
     1321 tgagtttttc cggaaaatgg taaagaccgt agttgttgga gcagttggtt acaatggtcg
     1381 gcaagccgta agtacgcaac cacgcgcgga cgaggtggtc gctggacgct ttagaggcag
     1441 agtaggggct ggacggcgcg tagggcgcgg tttcggtaaa caaatcgtcc gtgccgccta
     1501 aatcgccata gacttcatcg gtggaaatat ggtggaaacg gaaggcttcg tgctgttcag
     1561 acggcatttg ttgccagtag gcgcgggctg cttcaagtag gttgaatgtg ccgacgatat
     1621 tggtttggat aaactcgcct gccgaaccga tagagcggtc gacatggctt tccgccgcca
     1681 agtgcatcac ggcatcgggc cggtgttgtg cgaatacgcg gtcgagttcg gcgcggtcgc
     1741 aaatgtccac ttgctcgaaa gcatagcggg gattatcggc aatgtcggtc agcgattcga
     1801 gattgcccgc gtaggtcagt ttgtcgaggt tgacgacgga atcttgggtg tttcggat
//
LOCUS       DAXIDM010000188         1804 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000188 DAXIDM010000000
VERSION     DAXIDM010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1804
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.188"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(366..1433)
                     /gene="porB"
                     /locus_tag="ACFOAE_002042"
     CDS             complement(366..1433)
                     /gene="porB"
                     /locus_tag="ACFOAE_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002226789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric porin PorB"
                     /protein_id="HFC6885442.1"
                     /translation="MKKSLIALTLAALPVAAMADVTLYGTVKAGVEVSRVKNQGVKTK
                     TATQIADFGSKIGFKGQEDLGNGMKAIWQLEQKASIAGTNSGWGNRQSFIGLKGGFGT
                     VRVGNLNTVLKDSGDNVNAWESGSNTGDVLGLGTIGRVESREISVRYDSPVFAGFSGS
                     VQYVPRDNANDKDKYTHKQSSRESYHAGLKYENAGFFGQYAGSFAKYADLKDNAERVA
                     VGTTGAHPVKDYQVHRVVAGYDANDLYVSVAGQYEAAKNNDTNPATNGKKLEQTQVAA
                     TAAYRFGNVTPRVSYAHGFKAKVNGKKAARYQYDQVIVGADYDFSKRTSALVSAGWLK
                     QGKGAGKVEQTASMVGLRHKF"
BASE COUNT          483 a          405 c          429 g          487 t
ORIGIN      
        1 cctcaaatcc cgtcattccc gcgcaggcgg gaatctagac attcaatgct aaggcaattt
       61 atcgggaatg actgaaactc aaaaaactgg attcccactt tcgtgggaat gacgggatta
      121 aagtttcaaa atttattcta aatagctgaa actcaacgca ctagattccc gcctgcgcgg
      181 gaatgacggc atattttgac attgaataaa aaagactaaa aacaggaaaa agccaaacag
      241 aaaacagcga aacagaaaaa agccaaacag aaaacagcca aacagaaaac agccaaacag
      301 aaaacagcca aacagaaaaa agcctgtctg gcgacaggct ttttgttgat accaatcttt
      361 tcagattaga atttgtgacg cagaccaacc atgctggcag tttgttcgac ttttcccgcg
      421 cctttacctt gtttcaacca accggcagaa accagagcgg aagtgcgttt ggagaagtcg
      481 tagtcggcac caacgataac ttggtcgtat tgataacgtg ctgctttctt gccattcact
      541 ttagctttga agccgtgagc gtaagaaacg cgaggcgtta cgttgccgaa acggtaagcg
      601 gcagtagcgg caacttgagt ttgctcgagt tttttaccat tagtggcagg attagtatcg
      661 ttgtttttag cagcttcata ctgaccggca acagaaacgt acaggtcatt ggcatcgtaa
      721 ccggcaacta cgcggtgtac ttggtaatct ttaacaggat gggcacctgt agtacctact
      781 gcaacacgct ctgcattatc tttcaaatca gcatatttgg caaaagagcc tgcgtattga
      841 ccgaagaaac cggcattttc gtatttcaga ccggcgtggt aagactcacg gctggactgc
      901 ttatgtgtgt atttgtcctt atcattcgca ttgtcgcgcg gaacgtattg tacgctgccg
      961 ctgaagcctg caaatacggg agagtcgtag cgtacggaga tttcacggct ttctacacga
     1021 ccgatagtac ccagtcccag tacatctccg gtgttagaac cagattccca tgcattgacg
     1081 ttgtcgccgc tgtctttcaa tacggtgttc agattaccga cgcggacggt accgaagccg
     1141 cctttcaagc cgatgaagga ctggcggtta ccccagccgc tgttagtgcc ggcgatggag
     1201 gctttttgtt ccaactgcca aatggctttc atgccgttgc cgaggtcttc ttgacctttg
     1261 aaaccgattt tagaaccgaa gtcggcaatt tgggttgcag ttttggtttt tacgccttga
     1321 ttttttacgc gagaaacttc tacacccgct ttaactgtac cgtacagggt aacatcagcc
     1381 attgctgcaa caggcagggc agccagtgtc agggcaatca gggatttttt cattgctgta
     1441 ttccttttcg tagttaagaa atttaagcag gccgggcttt ccaagccgct tagctttgca
     1501 tttaccgccg acgttttcgg cgattccatg tctgaaacta tagatgttcc tgtctgaaaa
     1561 aacaaacttc tgcctgtttt tgtgtggaat tcgatgtgta ttttgaaggg cggatagaga
     1621 tattatgggt attttttgtt ttataacata tggttattta aattttttaa gatttgcatt
     1681 tttacaacac ttactcggga gggtattgga gggcattgca aaccgggggt tataaagacg
     1741 gcaaaaaacg cgcacgtggt ttctttcgga acgggcggat gcaaaacccg cccctgcggc
     1801 agga
//
LOCUS       DAXIDM010000189         1732 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000189 DAXIDM010000000
VERSION     DAXIDM010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.189"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            356..1660
                     /locus_tag="ACFOAE_002043"
     CDS             356..1660
                     /locus_tag="ACFOAE_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFC6885443.1"
                     /translation="MKKHIWAASLLPASLSAEPLNWWKPYSAVNSGDTAWVMTAAALV
                     LLMTLPGLALFYGGMVRKKNLLSTMMHSFSIATLVGILWVAVGYSLAFTPGNAFIGGL
                     GRVFLSGMQIDATAQMLTVSPNAPTVPEPVFMFFQMTFAIISTAIITGAFAERMKYSA
                     MMLFSGIWFLLVYVPGAHWVWGGGFMSKGGVLDYAGGTVVHINAGIAGLVAALVLGRR
                     IGYGREAMPPHNMAMTLIGAAMLWFGWFGFNAGSALAADAAAGMAMAVTQVSAVFGAA
                     GWLACEKIAGHKPSALGLASGAVSGLVGITPAAGFTGPSGAAAIGILTAAACFVSVTV
                     VKHKLRYDDSLDAFGIHGFGGLVGGILTGIFFDNRIFGGDAAVWQQLWIQVKDGFVMA
                     AYSGLMSWAILKVVGKICGGLRVGKDVEREGLDLNIHGERVE"
BASE COUNT          355 a          432 c          510 g          435 t
ORIGIN      
        1 aattaaaaat ttttaatata ttaatcaata aattaatttt ataaaataaa aatattgtca
       61 acaatatttt gccttatcgc ccaaacctct gtatattttc ctacagtaaa ttgttgacaa
      121 tccatacgcc cacatatgcg ccgcctaagg ataaatcctc ccgccggaca acgggtgcaa
      181 gggattggat gcgatatttc catattcaaa caagggattt gtttcacgca cagggcggca
      241 catcggcaaa atccccgcgc cgccccggtc cagcagggct tgcgtccctc ccggacaagc
      301 cccgaccccg cctttccgaa agacgggctc aaccattaag gaaactttaa tcaaaatgaa
      361 aaaacacata tgggcggcat ctttgctgcc ggcatcccta tcggcagaac ctttaaactg
      421 gtggaagcct tattccgccg tcaattcggg cgataccgcc tgggtgatga ctgcggctgc
      481 cttggtactg ttgatgacgc ttcccgggct ggctttattc tacggcggta tggtgcggaa
      541 aaaaaacctg ctctcgacga tgatgcacag cttttccatc gcgacattgg tgggcatcct
      601 ttgggtcgcc gtcggctatt ctttagcgtt cacgccggga aatgccttta tcggcggttt
      661 ggggcgtgta tttttaagcg ggatgcagat agacgctacc gcacagatgc tgaccgtgtc
      721 gcccaatgcg ccgactgttc ccgaaccggt atttatgttt tttcagatga cgtttgccat
      781 tatttcgacc gccattatta ccggcgcgtt tgccgaacgg atgaaatatt cggcaatgat
      841 gctgttttcg ggcatatggt ttttattggt ttatgtgccg ggcgcgcatt gggtgtgggg
      901 cggcggcttt atgagcaagg gcggcgtatt ggattatgcc ggcggtacgg tggtgcacat
      961 caatgccggt atcgcgggac tcgtcgccgc cttggttttg ggcaggcgca taggctacgg
     1021 gcgcgaggcg atgcctccgc acaatatggc gatgacactg atcggcgcgg caatgttgtg
     1081 gttcggctgg ttcggcttta acgccggatc ggcgcttgcg gcagacgcgg cggcgggtat
     1141 ggcgatggcg gtaacgcagg tgtcggccgt attcggcgcg gcaggctggc ttgcctgcga
     1201 aaaaatagcg ggacacaaac cttccgcttt ggggctggct tccggcgcgg tttccggtct
     1261 ggtcggcatc acccctgccg ccggctttac cggcccgtcg ggcgcggccg ccatcggtat
     1321 attgactgcc gccgcgtgct ttgtgtccgt caccgtcgtc aaacacaaat tgcgttacga
     1381 tgattctttg gacgctttcg gcatacacgg attcggcggg ctggtgggcg gaatattgac
     1441 cggcatcttt ttcgacaacc gcattttcgg cggggatgcg gcagtttggc agcagttgtg
     1501 gatacaggta aaagacgggt tcgttatggc ggcatacagc gggctgatga gttgggcgat
     1561 tttgaaggtc gtggggaaaa tctgcggcgg cctgcgcgtc ggcaaggatg tcgaacgcga
     1621 aggtttggat ctgaatatcc acggcgaacg cgtggaataa gggcggttat gccgtctgaa
     1681 gcctgaaaat cgggtttcag acggcatttt tcacgtttgc cgccgatgga ta
//
LOCUS       DAXIDM010000190         1652 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000190 DAXIDM010000000
VERSION     DAXIDM010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.190"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..800)
                     /locus_tag="ACFOAE_002044"
     CDS             complement(<1..800)
                     /locus_tag="ACFOAE_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002251720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer family protein"
                     /protein_id="HFC6885444.1"
                     /translation="MLKTPPTLAAELSGKTGVSISAPYANENSRILLSTTDISSENGK
                     IKIQSYGDQYYYARQSELYTFERRSYKTGKWYNRKHITEVKEHKNAKPDAVNLSASQG
                     IDIKSGGNIDAYATAFDAPKGSINIEAGRKLTLYAVEELNYDKLDSQKRRRFLGISYS
                     KAHDTTTQVMKTALPSRVVAESANLQSGWDTKLQGTQFETTLGGATIRAGVGEQARAD
                     AKIILEGIKSSIHTETVSSSKSTLWQKQAGWGSNIETLQLPSFTGPVAP"
     gene            complement(945..1376)
                     /locus_tag="ACFOAE_002045"
     CDS             complement(945..1376)
                     /locus_tag="ACFOAE_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885445.1"
                     /translation="MKNNIFLNLNKKSINNNHFVISIFFETIYQFETKDTLLECFKNI
                     TTTGHFGVIGAQYEKIDATRWIGDYEEVNGFEYIDKAPSIYFSVGDDFNPEELIIPIN
                     LAYHYFNIAISDFLIAHPEYQKKCKEIQKTYSQTNCSLHET"
     gene            complement(1392..>1652)
                     /locus_tag="ACFOAE_002046"
     CDS             complement(1392..>1652)
                     /locus_tag="ACFOAE_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemagglutinin"
                     /protein_id="HFC6885446.1"
                     /translation="DGGFKEISSIKTVYNPKKFSDDKILQMAQNAASQGYSKASKIAQ
                     NERTKSISERKNVIQFSETFDGIKFRSYFDVNTGRITNIHPE"
BASE COUNT          397 a          306 c          362 g          587 t
ORIGIN      
        1 ggcgcaacgg gaccggtgaa actcggcaat tgcaaggttt cgatgttact gccccatcct
       61 gcctgttttt gccatagagt agatttgctg ctgctcacgg tttctgtgtg gatgctgctt
      121 ttgatccctt cgaggataat cttggcatct gcccgtgcct gctcacctac gcctgcgcgt
      181 atggttgcgc cacccagtgt ggtttcaaac tgtgtgcctt gcagtttggt atcccagccc
      241 gattggaggt tggctgattc tgcaactacc cttgagggca gcgcggtttt catgacttgg
      301 gtggtggtgt cgtgtgcttt gctgtagctg atgccgagaa atctgcgcct tttttggctg
      361 tctagtttgt cgtagttgag ctcttctacg gcatagagtg tcaatttccg cccggcttcg
      421 atgttaatgc tgcctttggg ggcatcgaat gcggtggcgt aggcgtcgat gttgccacca
      481 gatttgatgt cgatgccttg ggatgcgctg aggtttactg cgtcgggctt ggcgtttttg
      541 tgttctttga cttcggtaat gtgtttgcgg ttgtaccatt tgccggtttt gtagctgcgg
      601 cgttcaaagg tatagagttc gctctgtctc gcatagtaat attggtcacc gtaagattga
      661 attttgattt tgccgttttc cgaactgata tccgtggtgc tgagcaggat gcgactgttc
      721 tcattggcat acggtgcgct aatgctcaca ccggttttac ccgaaagttc tgcagcaagc
      781 gtagggggtg tcttcagcac gcacgcgtct gggcagtata tagggaatct gaatatttac
      841 ttgcataaca aatgccgtct gaaaaattgt gagcttttca gacggcattg agccgtaaat
      901 catggaacgc gtgcgtgctg aagcacacac cttacgcatg gattttaggt ttcatgcagg
      961 ctacagtttg tttgagaata tgttttttgt atttctttac actttttttg atattcaggg
     1021 tgagctatta agaaatcaga tattgcaata ttaaagtaat gatatgctaa attaataggt
     1081 ataattaatt cttcaggatt gaaatcatct ccaactgaaa aataaataga aggagcttta
     1141 tcaatatact caaatccatt tacctcttca taatctccaa tccatctagt agcatctatt
     1201 ttttcatatt gagcacctat tactccaaaa tgtccggtag ttgtaatatt tttaaaacac
     1261 tctaaaagcg tatctttagt ttcaaattgg taaattgttt caaaaaaaat cgaaataaca
     1321 aaatggttgt tatttataga ttttttattt aagtttagaa aaatattatt tttcataatt
     1381 tttcctttaa attattctgg gtgaatgttt gtaattcttc ctgtatttac atcaaaatat
     1441 gatctaaatt tgattccgtc aaaggtttct gagaattgaa tgacattttt tctttccgat
     1501 attgatttag ttctttcatt ttgagcaatt ttagaggctt ttgaatatcc ttgtgaagca
     1561 gcattttgag ccatttgaag tattttatca tcagaaaatt ttttaggatt ataaacagtt
     1621 tttatacttg aaatttcctt aaatccacca tc
//
LOCUS       DAXIDM010000191         1631 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000191 DAXIDM010000000
VERSION     DAXIDM010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1631
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.191"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..1165
                     /gene="tuf"
                     /locus_tag="ACFOAE_002047"
     CDS             <1..1165
                     /gene="tuf"
                     /locus_tag="ACFOAE_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011793521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFC6885447.1"
                     /translation="RSKPHVNVGTIGHVDHGKTTLTAALTTILAKKFGGAAKAYDQID
                     NAPEEKARGITINTSHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAA
                     DGPMPQTREHILLARQVGVPYIIVFMNKCDMVDDAELLELVEMEIRDLLSSYDFPGDD
                     CPIVQGSALKALEGDAAYEEKIFELAAALDSYIPTPERAVDKPFLLPIEDVFSISGRG
                     TVVTGRVERGIIHVGDEIEIVGLKETQKTTCTGVEMFRKLLDEGQAGDNVGVLLRGTK
                     REDVERGQVLAKPGTITPHTKFKAEVYVLSKEEGGRHTPFFANYRPQFYFRTTDVTGA
                     VTLEEGVEMVMPGENVTITVELIAPIAMEEGLRFAIREGGRTVGAGVVSSVIA"
     gene            1183..1494
                     /gene="rpsJ"
                     /locus_tag="ACFOAE_002048"
     CDS             1183..1494
                     /gene="rpsJ"
                     /locus_tag="ACFOAE_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012504051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFC6885448.1"
                     /translation="MANQKIRIRLKAYDYALIDRSAQEIVETAKRTGAVVKGPIPLPT
                     KIERFNILRSPHVNKTSREQLEIRTHLRLMDIVDWTDKTTDALMKLDLPAGVDVEIKV
                     Q"
BASE COUNT          437 a          442 c          397 g          355 t
ORIGIN      
        1 acgtagcaaa ccgcacgtaa acgttggcac catcggtcac gttgaccatg gtaaaaccac
       61 cctgactgcc gctttgacta ctattttggc taaaaaattc ggtggtgctg caaaagctta
      121 cgaccaaatc gacaacgcac ccgaagaaaa agcacgcggt attaccatta acacctcgca
      181 cgtggaatac gaaaccgaaa cccgccacta cgcacacgta gactgcccgg ggcacgccga
      241 ctacgttaaa aacatgatta ccggcgccgc acaaatggac ggtgcaatcc tggtatgttc
      301 cgcagccgac ggccctatgc cgcaaacccg cgaacacatc ctgctggccc gtcaagtagg
      361 cgtaccttac atcatcgtgt tcatgaacaa atgcgacatg gtcgacgatg ccgagctgtt
      421 ggaactggtt gaaatggaaa tccgcgacct gctgtccagc tacgacttcc ccggcgacga
      481 ctgcccgatt gtacaaggtt ctgcactgaa agccttggaa ggcgatgccg cttatgaaga
      541 gaaaatcttc gaactggctg ccgcattgga cagctacatc ccgactcccg agcgtgccgt
      601 ggacaaaccg ttcctgctgc ctatcgaaga cgtgttctcc atttccggcc gaggtacagt
      661 agtaaccggc cgtgtagagc gcggtatcat ccacgttggt gacgagatcg aaatcgtcgg
      721 tctgaaagaa acccaaaaaa ccacctgtac cggcgttgaa atgttccgca aactgctgga
      781 cgaaggtcag gcgggcgaca acgtaggcgt attgctgcgc ggtaccaaac gtgaagacgt
      841 agagcgtggt caggtattgg ccaaaccggg tactatcact cctcacacca agttcaaagc
      901 agaagtgtac gtactgagca aagaagaggg cggccgccat accccgttct tcgccaacta
      961 ccgtccccaa ttctacttcc gtaccaccga cgtaaccggc gcggttactt tggaagaagg
     1021 tgtggaaatg gtaatgccgg gtgagaacgt aaccattacc gtagaactga ttgcgcctat
     1081 cgctatggaa gaaggcctgc gctttgcgat tcgcgaaggc ggtcgtaccg tgggtgccgg
     1141 cgtggtttct tctgttatcg cttaattgaa ggatattgat aaatggcaaa ccaaaaaatc
     1201 cgtatccgcc tgaaagctta tgattacgcc ctgattgacc gttctgcaca agaaatcgtt
     1261 gaaactgcaa aacgtaccgg tgccgttgta aaaggcccga ttcctttgcc gaccaaaatc
     1321 gaacgtttca acattctgcg ttctccgcac gtgaacaaaa cttcccgtga acaattggaa
     1381 atccgcaccc acttgcgcct gatggacatc gtggattgga ccgataaaac taccgatgcg
     1441 ctgatgaagc tggatttgcc ggccggtgtt gatgtagaaa tcaaagtcca ataattcgga
     1501 ctattgaaaa tccccaagca atcaatgctt ggggattttt tatgttatgc cgagaccttt
     1561 gcaaaattcc ccaaaatccc ctaaattccc accaagacat ttaggggatt tctcatgagc
     1621 accttcttcc a
//
LOCUS       DAXIDM010000192         1554 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000192 DAXIDM010000000
VERSION     DAXIDM010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.192"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..217)
                     /locus_tag="ACFOAE_002049"
     CDS             complement(<1..217)
                     /locus_tag="ACFOAE_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HFC6885449.1"
                     /translation="MKELHTSELVEVSGGKFHIFAQGGGNLGKKDMVAVGKIGASYSP
                     NNSGVEFSVSKQFGYVQGLGVQFSKPTF"
     gene            complement(1252..1554)
                     /locus_tag="ACFOAE_002050"
                     /pseudo
     CDS             complement(1252..1554)
                     /locus_tag="ACFOAE_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557955.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          480 a          299 c          267 g          508 t
ORIGIN      
        1 caaaagtagg tttcgaaaac tgtacaccaa gaccttgtac atatccaaat tgcttgctaa
       61 cagaaaactc tactccacta ttgttagggg aataggaagc accaatttta ccaacagcaa
      121 ccatatcttt tttacctagg ttgccgccac cctgtgcaaa gatatggaat ttgccacctg
      181 acacttcaac taattcagag gtgtgtaact ctttcatgat tttctcctgt aaagaagtat
      241 ggttggaaat gtaaatcaga attaaccttt cttaagttta atttaatact ttttttgcaa
      301 gtattttatt ttaaattaaa tcaatatttt aaaaatattt acttgtatac tgaaaaagaa
      361 actcctaatg gtggagtggg gcttttgttt aagtaagcat taaaaaaatt tagatttccc
      421 attatgatta acttaatgca agagcttttt caggacgtac aaaccagcga acgggcgttc
      481 tgatgtgggc aggttggttg tcgctaacca atttcagtag ctcaatcgtc agattggtat
      541 ccgaccctat caagctaagg agaggctgcg gctactacac aaagcacctg aaattattgg
      601 gtgcttttgt ctttttatgg cattgtacca atttgtgtac cacgagggct tgttcgccca
      661 aacgcggtaa caactgaata cacactttcc ccctcaactt ctttgcgttc taaaacgact
      721 gtcccaatcc gagaatagac aatcatagga cgatgattgc cccttacatc actaaattca
      781 ctaaaaattt ttgcgcctga ttgaaaaatc atttccacat aaaagggtta cacctgtttc
      841 atcgtggctt aatccaaacc gcgttaaatc tgctttgtgt tctgccaaaa tgtgaatcac
      901 accaaagccg tgattaacct ttttgtgttc gccgtgtttt aaaacaattt gacctgccgg
      961 gaagtctgct ctattgttcg gacaataggg ggaatatacc aattacttta actacatcat
     1021 tttttgacat ttttcttgcc tttcaattta aaatccaaaa tcatactgcc ataatttagc
     1081 aatccaaaaa aatttaggca gcagtaatgg tttcgtattt tagaaaacga aacttggttt
     1141 ggtgttttga agcatttcag tacacaaaca tggaatttta aattgtcttg tgttgccttg
     1201 atttaggatg ttccagtttt ttaataaata gtttggggct gtcctagata actaagataa
     1261 actcgatttt actaattgtt ttaaaatgga acaagaactt ttatctcact gttgttaaaa
     1321 cgccattcgc actcctttaa atacagctca aaatgcgctt tgggaatgcc gttaaacttg
     1381 cgtaaatgac gttttgcctg gttccaaaag ttctcaattc cattaatatg gttttgtcgt
     1441 tcagcaaaat gtgtgctgtg attgatacga aaacgaaatt tcagcgaagc taaaatggct
     1501 aaattcgctc acatctaata catcatagct acgataacaa tccgtataaa caat
//
LOCUS       DAXIDM010000193         1528 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000193 DAXIDM010000000
VERSION     DAXIDM010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1528
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.193"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(17..826)
                     /locus_tag="ACFOAE_002051"
     CDS             complement(17..826)
                     /locus_tag="ACFOAE_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002253501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HFC6885450.1"
                     /translation="MSHLFRKEVFVAQQNKWTGQVILTRPFSFLFLTFCAFLIALCII
                     IFLIFGSYTNKTTVEGQLLPTMGVVRVYSSDIGTITHKFVEDGNFVKAGEPLFKLSTS
                     RFGEKGNVQAKLAAEANLKKTLALQELERLKRIHQNEQKNVHNNIHRLNNQLENIKQQ
                     ITGQNRQIRLAEKTLNKNKFLASQGAVSQQDKMTAESHLLEQRSRLESLKREQNNAIR
                     ELDEQKITLSSLPERHKTELSQLNRAITEMNQEILDFDLKSEQTIRASKSG"
     gene            complement(840..1010)
                     /locus_tag="ACFOAE_002052"
     CDS             complement(840..1010)
                     /locus_tag="ACFOAE_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885451.1"
                     /translation="MNTETIYATVFCILAATISGLLVKFNVIKIETSINSKFMLLGIS
                     ILIIGIFLSIFF"
BASE COUNT          481 a          250 c          265 g          532 t
ORIGIN      
        1 tatttttgca aaggtctcaa cctgatttac tagctcgtat ggtttgttcg gatttcaaat
       61 caaaatccaa aatttcttgg ttcatttccg taatcgcacg gttgagttgg ctcaattcgg
      121 ttttatggcg ttcaggcagg ctgcttaatg tgattttctg ttcatcaagt tccctgattg
      181 cattattttg ttcacgtttt aggctctcca aacgtgagcg ttgttccaat aaatggcttt
      241 cggcggtcat cttatcttgt tgggatactg cgccttgact ggctaaaaac ttgttcttgt
      301 taagggtttt ttccgctaaa cgaatttgac gattttgccc tgtaatttgc tgtttaatat
      361 tctctaattg attgtttaaa cgatgaatgt tgttatgaac atttttttgc tcattttgat
      421 gaatgcgctt taaacgttcc aattcttgta atgccaaagt ttttttaagg ttggcttctg
      481 ctgccaattt ggcttgtacg tttccttttt cgccaaaacg cgatgtggaa agtttgaaca
      541 atggttcgcc agctttgaca aagttaccat cttcaacaaa tttatgcgta atcgtgccga
      601 tatcggaaga gtaaacacga accaccccca tagttggaag taattgacct tcaacggttg
      661 ttttattggt atagctacca aaaatcaaaa agataatgat acacagagca atgagaaaag
      721 cgcaaaaagt cagaaataaa aaagagaatg gacgggtcaa gataacctga cctgtccact
      781 tattttgttg ggctacaaag acttcttttc ggaataagtg ggacatttat tattatttct
      841 taaaaaaaaa tggatagaaa aataccaata attaaaatac ttatgcctaa taacataaat
      901 ttgctattga ttgatgtttc tattttaatt acattaaatt taaccaataa tccagaaatg
      961 gttgcagcta aaatgcaaaa gacagtggcg taaatggttt cagtattcat aatttttctc
     1021 tttcaaaatt gttcaatcta aatagaaaaa ggtaacttca atacatattg ctgtaactga
     1081 aattaccttt tccttaatga tgtaattatc ttatggcttc atcatgccac gaccgatatt
     1141 gtatccgcca gcaacagaga aaataccagc tcccattgcg tcaacccagc ctactggtcc
     1201 tgtccacttg ttccgttgag ctacaaagac ttctggtctg aaaaatgagt gattgttaga
     1261 catgtgtact tatttatgtt tctttgattg ggataaattt gtaaaaacaa aaaaaaggca
     1321 agttgttatt atagaagaac ttaaaatgct taacatactc attgaggttt gtaccacata
     1381 atgagatacg agataatttg ttgggagtaa aatcaaaaaa aagattaaat atttaaaata
     1441 atcactatat tttttcatta tttgttcctt tttgtattta agttcttatg aaaaactagg
     1501 gtattttgaa tagaaaatat caaaatac
//
LOCUS       DAXIDM010000194         1508 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000194 DAXIDM010000000
VERSION     DAXIDM010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1508
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.194"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            172..963
                     /locus_tag="ACFOAE_002053"
     CDS             172..963
                     /locus_tag="ACFOAE_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="opacity family porin"
                     /protein_id="HFC6885452.1"
                     /translation="MNPAPKKSLLFSSLLFSSLLFSSAAQAASKDNDRSPYYVQADLA
                     YAAERITHNYPEPTGADKDKISTVSDYFRNIRAHSIHPRVSVGYDFGDWRIAADYASY
                     RKWNSNKYSVNTKEVQENGNTRQDLKTENQENGTFHAVSSLGLSAIYDFKLNDKFKPY
                     IGARVAYGHVRHSIDSTKKTTNVVTVAGAANIAPTIYYAPETQNAYHESHSIRRLGLG
                     VIAGVGFDITPKLTLDTGYRYHNWGRLENTRFKTHEVSLGVRYRF"
BASE COUNT          406 a          435 c          325 g          342 t
ORIGIN      
        1 atagtacgga accgactcac ttggtgcttc agcaccttag agaatcgttc tcttttttgt
       61 tcatccgcta tattgtgttg aaacatcgcc ccaaacccga tacaatccac ccctacaaca
      121 tcagtgaaaa tctttctttt taatcagtta aaaccgaata cggagtcgaa aatgaatcca
      181 gcccccaaaa aatctcttct cttctcttct cttctcttct cttctcttct cttctcttcc
      241 gcagcgcagg cggcaagtaa agacaatgat cgcagcccgt attatgtgca ggcggattta
      301 gcctacgccg ccgaacgcat tacccacaat tatccggaac caaccggtgc agacaaagac
      361 aaaataagca cagtaagcga ctatttcaga aacatccgtg cgcattccat ccacccccgg
      421 gtgtcggtcg gctacgattt cggcgactgg aggatagcgg cagattatgc cagttacaga
      481 aaatggaaca gcaataaata ttccgtaaac acaaaagagg tgcaagaaaa cggtaacacc
      541 aggcaagacc tgaagacgga aaatcaggaa aacggtacat tccacgccgt ctcatcgctc
      601 ggtttgtccg ccatttacga tttcaaactc aacgataaat tcaaacccta tatcggtgcg
      661 cgcgtcgcct acggacacgt cagacacagc atcgattcga ccaaaaaaac aacaaatgtt
      721 gttaccgtcg ccggtgctgc taacatagca cctacgattt attatgcacc agagacgcaa
      781 aacgcctatc acgaaagcca cagcatccgc cgcttgggtc ttggtgtcat cgccggtgtc
      841 ggtttcgaca tcacgcccaa gctgaccttg gacaccggat accgttacca caactgggga
      901 cgcttggaaa acacccgctt caaaacccac gaagtctcat tgggcgtgcg ctaccgcttc
      961 tgattccccg acaccgatgc cgtctgaacc ttcagacggc attttttaca caattcccac
     1021 cgtttcccat cattcccgat acaccgtaat ctcgaaaccc gtcattcccg cgcaggcggg
     1081 aatctatcgg aaatgactga aaccccgaga ttctagattc ccactttcgt gggaatgacg
     1141 gttcagttgc gttccgacaa caccgtaatc ttgaaacccg tcatttccga caacgccgca
     1201 atcttgaaat tcgtcattcc cgcgcaggcg ggaatccaga cccacgacgc ggcgggaatc
     1261 tatcggaaat gactgaaacc ccgcgttcta gattcccact ttcgtgggaa tgacgggatg
     1321 taggttcgta ggaatgacgt ggtgcaggtt tccgtgcgga tggattcgtc attcccgcgc
     1381 aggcgggaat ccagacccct gacgcggcgg gaatctatcg gaaatgactg aaaccccgag
     1441 attctagatt cccacttccg tgggaatgac ggttcagttg cgctccgaca ataccgcaat
     1501 ctcgaaat
//
LOCUS       DAXIDM010000195         1494 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000195 DAXIDM010000000
VERSION     DAXIDM010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1494
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.195"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..958
                     /locus_tag="ACFOAE_002054"
     CDS             <1..958
                     /locus_tag="ACFOAE_002054"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002255297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFC6885453.1"
                     /translation="AKVAKVAKVAKVAKVAKVAKVAATAQKEAAPAQQQGGIRFSDGI
                     AAVADNEVITRRRLAEAVAEAKANLPKEAQISESELSRQVLMQLVNQSLIVQAGKRRN
                     IQASEAEIDAVVAKNSALKNLSPAQRRDFADNIIAEKVRQQAVMQNSRVSEAEIDAFL
                     EQAQKQGITLPEGAPLRQYRAQHILIKADSENAAVGAESTIRKIYGEARSGTDFSSLA
                     RQYSQDASAGNGGDLGWFADGVMVPAFEEAVHALKPGQVGAPVRTQFGWHIIKLNEVR
                     DAGTPQERIRNSVRQYIFQQKAEQATVNLLRDLHSGAYVDIR"
BASE COUNT          407 a          430 c          382 g          275 t
ORIGIN      
        1 tgccaaagtt gccaaagttg ccaaagttgc caaagttgcc aaagttgcca aagttgccaa
       61 agttgccgcc acggcgcaaa aagaagccgc acccgcacaa cagcagggcg gtatccgctt
      121 ttcagacggc attgccgccg ttgccgacaa cgaagtcatc acgcgccgcc ggcttgccga
      181 agccgttgcc gaagccaaag ccaacctgcc caaagaggcg cagataagcg aatccgagct
      241 gtcccgacag gtgctgatgc agcttgtcaa ccaatccctg attgtacagg cgggcaaacg
      301 ccgcaacatt caagcaagcg aagcggaaat cgatgccgtc gtcgcaaaaa attccgccct
      361 caaaaacctc agccccgccc aacgccgcga ttttgccgac aacatcattg ccgaaaaagt
      421 ccgccagcag gcagtgatgc agaacagccg cgtgagcgaa gctgaaatcg atgccttcct
      481 cgagcaggcg caaaaacaag gcatcaccct gcccgaaggc gcaccgttgc gccaataccg
      541 cgcccaacac atcctgatta aagccgacag cgaaaacgcc gccgtcggcg cggaaagcac
      601 catccgcaaa atctacggag aggcccgcag cggcacagac ttttccagcc tagcgcgcca
      661 atattcgcaa gacgcgagcg cgggcaacgg cggagatttg ggctggtttg ccgacggcgt
      721 gatggttccc gcctttgaag aagccgtcca cgcgctcaaa cccggacagg tcggcgcgcc
      781 cgtccgcacc caattcggct ggcatatcat caaattgaac gaagtgcgcg atgccggcac
      841 acctcaggaa cgtatccgca attccgtgcg gcaatacatc ttccaacaaa aagccgaaca
      901 ggcaaccgtc aacctgttgc gtgacctgca ttccggcgcg tatgtcgaca tccgctaagg
      961 cggtttgaag caaaaagcca taccgatcgg caaaaatccg ggcggtatgg ctttttggat
     1021 ttcgagttac ttttacaccg tcattcatca ttcccgcgaa agcgggaatc tagaaacgaa
     1081 aagtaacagg aatttatcgg gaatggctgg agtttaaagg actggattcc cgccgtcgcg
     1141 ggaatgacgg gattttgggt tgtggtaatt tatcggaaaa acaaaaaaac ctatgccgtc
     1201 attcccgagc aggcgggaat ccggttattt aaaactgcag aaatttatcc gaagcaacaa
     1261 caatctttcc atcgtcattc ccgcgtaggc gggaatctag gacgtagaat ctaaagaaac
     1321 cgttttatcc gataagtttc tgtaccgaag aatctggatt cccgctttcg cgggaatgac
     1381 ggcgcataag ttcccgtgcg gacagaccta gattcccacc tgcgtgggaa tgacgattca
     1441 gaagttgcct gaaacctaaa aaactgaaac cgaacgagcc ggatttccgc tttc
//
LOCUS       DAXIDM010000196         1484 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000196 DAXIDM010000000
VERSION     DAXIDM010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1484
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.196"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            37..1380
                     /locus_tag="ACFOAE_002055"
     CDS             37..1380
                     /locus_tag="ACFOAE_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFC6885454.1"
                     /translation="MEDKQGMTKAVAGVMTDAPADGRKPATASNLPPLSNRGGTETET
                     AGRVQEVFECYETYITDGKGNLLGVPLRRGVSDSAFIDQISFSFHEKTFFDKYGVRVS
                     LLEDEDFIRAASMLAEEVFGFGIYKESKGSGGRFYERCWLMGSEDVLYGRVHFGGQNN
                     TILFELTGTGCGVAKEGWESRLFAFLTNAIRPKITRVDIAKDFFNGEYSPNQAREDRN
                     KGMFTCHHVKPKGECLGSDWEEDDEAKMTKGKTYGIGSRESSKYVRVYEKGKQLGDKT
                     STWTRFEIEFKAKDIVIPFEVLQNPGEYFGGAYPICERFVQKATRIHAVKEDKVISAD
                     RYLEWVKKQFGRAANGLKFIFPELDKAKLFELIEPSHHKLPKSLAPEAYDCAFLKAQA
                     IHEQPAFKPYKDPYYMYEYYENLEKQLEQQKHVNNEESYNNFIYDKFARLPISWA"
BASE COUNT          451 a          345 c          351 g          337 t
ORIGIN      
        1 agggcttttt tttgcccgtt tttgaggatt cgcaccatgg aagataagca agggatgaca
       61 aaggcggttg ccggcgtgat gacggacgcg ccagcggacg gcaggaagcc ggcaaccgct
      121 tcaaatcttc cccccttatc taacaggggg gggacagaaa ccgaaacggc aggcagggtt
      181 caggaagtct tcgaatgtta cgaaacgtac ataacggacg gtaaaggaaa cctgttaggc
      241 gttcctcttc ggcgcggtgt atcagattcg gcgttcatcg atcaaattag cttttcattt
      301 catgaaaaaa cctttttcga taaatacggc gttcgtgtaa gtcttttgga agacgaagat
      361 ttcattcgcg ccgcgtccat gctcgccgaa gaagttttcg gtttcggtat ctacaaagag
      421 tccaaaggct cgggcggtcg tttttatgag cgctgttggt tgatgggttc ggaagacgtc
      481 ctatacggtc gcgtccattt tggcggacaa aacaatacca tccttttcga actgaccggc
      541 accggttgcg gcgtcgcaaa agaaggctgg gaatcacgac ttttcgcatt cctgactaat
      601 gcaatccgcc caaaaatcac acgcgttgac atcgcaaaag actttttcaa cggcgaatac
      661 agcccgaacc aagcccgtga agaccgaaat aaaggtatgt ttacctgtca tcacgtcaaa
      721 ccaaaaggcg aatgtttggg gtcagattgg gaagaagacg atgaagccaa aatgaccaaa
      781 ggcaagacct atggtatcgg ctcccgtgaa tcgtccaaat atgtccgcgt ctatgaaaaa
      841 ggcaagcagt tgggcgataa aacaagcaca tggacgcgat ttgaaattga attcaaagca
      901 aaagatatcg ttatcccttt cgaagttttg cagaatccgg gcgaatattt cggcggcgca
      961 tatccgattt gcgaacgatt cgtccaaaag gcaacgcgca tacacgcggt taaggaagat
     1021 aaggtcattt cagccgaccg ctaccttgaa tgggtaaaaa aacagttcgg acgtgcggca
     1081 aacggtctga aattcatttt tcccgaattg gacaaagcca aactgtttga actgattgag
     1141 ccgagtcatc acaagctgcc caagtctttg gctcccgaag cctacgactg cgcctttttg
     1201 aaagctcaag ccattcatga acagcccgca ttcaaaccgt acaaagaccc ttactatatg
     1261 tacgaatatt acgagaatct tgaaaaacag cttgaacagc aaaaacacgt caacaatgaa
     1321 gaaagctata acaacttcat ttacgacaaa ttcgcaagac taccgatttc atgggcttaa
     1381 agtgtctgtc cgaaagacgt ttaatcacac aaggaaacca aaaaatgaac atccaacttc
     1441 aaggccacat cgtcggcgtt aaaaaaatca acggacaaat cgaa
//
LOCUS       DAXIDM010000197         1476 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000197 DAXIDM010000000
VERSION     DAXIDM010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.197"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            152..931
                     /gene="yaaA"
                     /locus_tag="ACFOAE_002056"
     CDS             152..931
                     /gene="yaaA"
                     /locus_tag="ACFOAE_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HFC6885455.1"
                     /translation="MFFVLSPAKNLNEKDPAPVSEFTQPDLLAESDILMQQLRELAPQ
                     QIAELMHVSDKIALLNAQRNAEWNTPFTPENAKQAVFMFNGDVYEGMDANTLDIGQIR
                     YLQNHVRLLSGLYGLLRPLDLIQPYRLEMGTPFANLRGKNLYEFWGDIITNLLNDTLA
                     QAGSNTLVNLASQEYFKSVNTKKLRARLITPIFKDEKNGKYKIISFYAKRARGLMVRY
                     AAEHNITDPEMLKNFNYEGYAFNDAASNESEWVFMRSEQIK"
     gene            1012..1102
                     /locus_tag="ACFOAE_002057"
     tRNA            1012..1102
                     /locus_tag="ACFOAE_002057"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1046..1048,aa:Ser,seq:tga)
     gene            1315..1404
                     /locus_tag="ACFOAE_002058"
     tRNA            1315..1404
                     /locus_tag="ACFOAE_002058"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1349..1351,aa:Ser,seq:cga)
BASE COUNT          417 a          350 c          333 g          376 t
ORIGIN      
        1 gacgaagccg aagacagtac agatagtacg gcaaggcgag gcaacgctgt actggtttaa
       61 atttaatcca ctatacttca cttttaatcg gcttgcccgc aaacacgttt aaacttaaaa
      121 tccccgtgtt tgacacaata ccgagcagat tatgtttttt gtcctttccc ctgcgaagaa
      181 ccttaatgaa aaagaccctg cccctgtcag cgagtttacc caacccgacc tgctggcaga
      241 gtccgacatt ctaatgcagc agttgcgcga gcttgcgccg caacagattg ccgaactgat
      301 gcacgtttcc gacaaaattg ccctcttaaa cgcgcagcgc aatgcagaat ggaacacgcc
      361 gtttacgccg gaaaacgcca aacaggcggt ctttatgttc aacggcgatg tttacgaagg
      421 tatggatgca aacacattgg atattggaca gatacgctat ctgcaaaacc atgtccgcct
      481 gctgtccggt ctgtacggtc ttctgcgccc gttagacctg atacagcctt accgcctgga
      541 aatgggaacg cccttcgcca atttgcgcgg caagaatttg tatgagtttt ggggcgacat
      601 cattaccaac cttttaaatg acacgcttgc ccaagcaggc agcaatacgc ttgtcaacct
      661 tgcctcacag gaatatttca agtccgtcaa cacgaaaaaa cttcgggcgc ggctgattac
      721 cccgatattt aaagacgaaa aaaacggcaa atataaaatc atcagtttct atgccaagcg
      781 cgcgcgagga ttaatggtgc gctatgcggc agaacacaat attaccgatc ctgaaatgct
      841 gaaaaatttt aattacgaag gctacgcatt taatgacgcg gcttccaatg aaagcgaatg
      901 ggtgtttatg cgttcggaac aaataaagta aaaacaaaaa agtaggtatt ttttgaaaaa
      961 aacacttggc aaagtatacg aactttatta ttattctagt ttcaagaaaa cggaagcgtg
     1021 gcagagcggt ttaatgcaac ggtcttgaaa accgtcgagg gttgatagcc ctccgtgagt
     1081 tcgaatctca ccgcttccgc caatccttga ggtcaaaaac caaataaaaa tgaagtagca
     1141 taaagcatcg gcatttttat ttggttttac ttcatcgtgt ttccttttcg gttgaacccc
     1201 accctttagg gcggtagaat cagactttat ttgggagggg tgtaaccctt tctgaatcag
     1261 ggtaacacat agggcggtgc tttatgtgtc gtcctgtgtg ttgaaacatc tttcggaaac
     1321 gtggcagaga ggctgaatgc agcggactcg aaatccgctg agggtgcaaa tcctccgtgg
     1381 gttcgaatcc caccgtttcc gccacaaaac aaaaccgccc tgattcgggg cggttctttt
     1441 ttgttcaagt tgagaccttt gcaaaattcc tttccc
//
LOCUS       DAXIDM010000198         1451 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000198 DAXIDM010000000
VERSION     DAXIDM010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.198"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            160..393
                     /locus_tag="ACFOAE_002059"
                     /pseudo
     CDS             160..393
                     /locus_tag="ACFOAE_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(467..973)
                     /locus_tag="ACFOAE_002060"
     CDS             complement(467..973)
                     /locus_tag="ACFOAE_002060"
                     /inference="COORDINATES: protein motif:HMM:NF044726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFC6885456.1"
                     /translation="MASIILNYLEKDGRPVIHGMGYISEWKINNGKVFYNISDTILNE
                     LLLKSGRSMFLLMDWSVFNSLPGKYCGILYKLCKDYAGIGKTPYFTVQEFRHYLGLDD
                     KEYEEFRALKAKIIKPAIEHINNSENVDIKIIPQLKRENRRVVGLHFDIEYKTNIEKT
                     TRTWQTRI"
BASE COUNT          385 a          329 c          259 g          478 t
ORIGIN      
        1 ctaaaatttt agtgaccgaa caaactcgaa aaatccacat cgccgatgcg ttccagccgg
       61 tcggcaaagc tgtcaagatt cacagattca gcgtttgaga cctttgcaaa attccccaaa
      121 atcccctaaa ttcccaccaa gacatttagg agatttctca tgagcacctt cttccagcaa
      181 accgcacaag ccatgattgc caaacacatc gaccgtttcc cgctattgaa gttggaccag
      241 gtgattgatt ggcagccgat cgaacaatac ctgaatcgtc aaagaacccg ttaccttaga
      301 gaccaccgcg gccgtcccgc ctacccgctg ttgtccatgt tcaaagccgt tctgctcgga
      361 caatggcaca gcctctccaa tcccgaactc gaacgtggtg ttttggtttc cagaaattta
      421 atcagtgtgg ctagcggctc tattttcgat tcagaaaagg ctgtttctat atcctcgtct
      481 gccatgttct ggttgttttt tctatatttg ttttgtattc aatatcaaaa tggagtccca
      541 caacccgcct attttcccgt tttaattgcg gtataatttt gatgtccaca ttttcactgt
      601 tgttgatatg ctctattgcc ggtttaatta ttttggcctt caacgctcta aattcttcgt
      661 attctttgtc atccaatccc aaatagtgtc taaattcttg aacggtaaaa tagggggttt
      721 tgccgatgcc tgcgtaatcc ttgcacaatt tgtataggat tccgcaatat tttcccggta
      781 agctattgaa cacactccaa tccatcagca aaaacatgct tcttccgctt ttcaatagta
      841 actcattaag aatggtgtct gatatattgt agaaaacttt gccattgttg atcttccact
      901 ctgaaatata gcccataccg tgtatgacgg gacggccgtc tttctccaaa taattcaaaa
      961 tgattgatgc cattcgtaga gcatccaagt cttttttagt tgttttcttt gaagttgata
     1021 tccaatacaa cgttccagat ctaagatatc tatcgcaaca aaaccgttgt catcataagt
     1081 accaccttat tcaaaatgtg ttttaatctt ctgcaaaaaa agataccaat acttgtattg
     1141 catttcagtc aaggaatggc ccatgtggat taaggattgc ggtgtttttt gtttatcaat
     1201 atggtttgat gtcattttga tttccatttc atgtggctac tatatctctc tattatgcac
     1261 taatacacag agtttcttga tgttagaacg aatacggcgt ccgtgtcggc gtgaaattct
     1321 gattttcctt atacgaaacc gcaaaccttt attacatctc ctgaataatt taggatactt
     1381 tttaggtatt gaaaaacacc ttggttttta gcctatgttc ggtgagtcgg ggaaatctat
     1441 atcttcgtcc g
//
LOCUS       DAXIDM010000199         1441 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000199 DAXIDM010000000
VERSION     DAXIDM010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1441
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.199"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            27..1364
                     /locus_tag="ACFOAE_002061"
     CDS             27..1364
                     /locus_tag="ACFOAE_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014573846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HFC6885457.1"
                     /translation="MSNHTSWSSKIGFVLAAAGSAIGLGAIWKFPYTAGTNGGAVFFL
                     LFLIFTVLVALPVQLAEFYIGRTGGKNAVDSFRALRPSTQWLWVGRMGVSACFILLSF
                     YSVVGGWVLNYVVHSFTGAVHTGADFEALFGATISNPAGSLSYQALFMLITVWVVKGG
                     ISDGIEKANRYLMPGLFILFIALAIRSLTLPGAMEGVSFLLKPNWSYFKADTMITALG
                     QAFFALSIGVSAMITYASYLGKDQDMFRSGHTIMWMNLLVSLLAGLVIFPAVFAFGFE
                     PSQGPGLIFIVLPAVFMKMPFGTVLFAVFMLLVVFATLTSAFSMLETVIAATIRQDER
                     KRKKHTWLIGTAIFIVGIPSALSFGVWGEFKVFGKTIFDLWDYVISAVIMPVGALGVA
                     VFTAWIQDKQSVLKDAGAGSTVPRAVLLLWLNTLRYLAPIAIIIVFINSLDIL"
BASE COUNT          261 a          341 c          389 g          450 t
ORIGIN      
        1 tatcttcaca tttcttaata aattttatga gtaaccatac ttcttggtcg tccaaaatcg
       61 gtttcgtgct tgctgcggca ggttcggcca tcggtttggg cgcgatttgg aaatttcctt
      121 atacggcagg caccaacggc ggcgcggtgt ttttcctgct gtttttgata tttaccgtct
      181 tggtcgccct gcccgtccag cttgccgagt tttatatcgg gcgcacaggc ggtaaaaatg
      241 ccgtcgattc cttcagggct ctgcgtccga gtacgcaatg gctttgggtc gggcgcatgg
      301 gcgtttccgc ctgctttatt ttgctgtcat tttacagcgt ggtcggcgga tgggtattaa
      361 attatgtcgt ccacagtttc acgggggcgg ttcataccgg cgcggacttt gaagccttgt
      421 tcggcgcgac gatttccaat ccggcaggtt cgctgtccta tcaggcactg tttatgctga
      481 ttacggtttg ggtggtcaaa ggcggcattt cagacggcat tgaaaaggca aaccgttatc
      541 tgatgccggg gctgtttatc ctctttattg cgctggcaat ccgttcgctg acgctgccgg
      601 gtgcaatgga gggcgtgtct ttcctgctca aaccgaattg gtcgtacttt aaagccgata
      661 cgatgattac ggctttaggt caggcgtttt ttgccttgag catcggcgtt tccgctatga
      721 ttacctatgc ttcgtatttg ggaaaagatc aggatatgtt ccgctcgggg catacgatta
      781 tgtggatgaa cctcttggtt tcgctgttgg caggtttggt gatttttccg gcggtgttcg
      841 ccttcggttt tgaaccgagc caggggccgg gattgatttt tatcgtattg ccggcggtgt
      901 ttatgaaaat gccgttcggt acggttttgt ttgcggtatt tatgctgctg gtcgttttcg
      961 ccacgctgac ttcggcattt tcgatgttgg aaacggtcat tgccgcaacc atccgccaag
     1021 acgagcgcaa acgcaaaaaa cacacttggc ttatcggcac ggccattttc attgtcggca
     1081 tcccatccgc gctgtctttc ggcgtatggg gtgagtttaa ggttttcggc aaaaccattt
     1141 ttgatttgtg ggactatgtt atttccgccg tcattatgcc tgtcggcgcg ttgggcgttg
     1201 ccgtatttac cgcctggatt caggacaagc agtctgtgtt aaaagatgcc ggcgcgggca
     1261 gcaccgtacc acgggcagtg ttgctgctgt ggctgaatac cttgcgctac ctcgccccga
     1321 ttgccattat tattgttttc atcaattctt tggacatcct ttaaaagcca tccaaacagc
     1381 aaaaatgccg tctgaaagcc tttcagacgg catttttgct tcaggttcag cctatttcgt
     1441 t
//
LOCUS       DAXIDM010000200         1432 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000200 DAXIDM010000000
VERSION     DAXIDM010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.200"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     regulatory      76..120
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            125..598
                     /gene="queF"
                     /locus_tag="ACFOAE_002062"
     CDS             125..598
                     /gene="queF"
                     /locus_tag="ACFOAE_002062"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HFC6885458.1"
                     /translation="MSRNNEELQGISLLGNQKTQYPTGYAPEILEAFDNKHPDNDYFV
                     KFVCPEFTSLCPMTGQPDFATIYIRYIPHIKMVESKSLKLYLFSFRNHGDFHEDCVNI
                     IMKDLIALMDPKYIEVFGEFTPRGGIAIHPFANYGKAGTEFEALARKRLFEHDAQ"
     gene            673..1359
                     /locus_tag="ACFOAE_002063"
     CDS             673..1359
                     /locus_tag="ACFOAE_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002228970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1990397 - queuosine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HFC6885459.1"
                     /translation="MYAFTDAQQQKALFWLVLFHILIIAASNYLVQFPFQIFGIHTTW
                     GAFSFPFIFLATDLTVRIFGSHLARRIIFWVMFPALLLSYVFSVLFHNGSWTGLGALS
                     EFNTFVGRIALASFAAYALGQILDIFVFNKLRRLKAWWVAPTASTVIGNALDTLVFFA
                     VAFYASSDGFMAANWQGIAFVDYLFKLTVCGLFFLPAYGVILNLLTKKLTTLQTKQAQ
                     DRPAPSLQNP"
BASE COUNT          338 a          442 c          299 g          353 t
ORIGIN      
        1 acacggaaaa cgccgccgtc caaaccatgc cgtctgaaga aaactacaca gataccgccg
       61 cttatattac aatcgccgcc cgtggttcga aaacctccca cattaaaaaa ctaaggaaac
      121 cctcatgtcc cgcaacaacg aagagctgca aggcatctct cttttgggca atcaaaaaac
      181 ccaatatccg accggctacg cgcctgaaat tctcgaagca ttcgacaaca aacatcccga
      241 caacgactat ttcgtcaaat tcgtctgtcc cgagttcacc agcctctgcc ccatgaccgg
      301 gcagcccgac ttcgccacca tctacatccg ctacattccg cacatcaaaa tggtggaaag
      361 caaatccctg aaactctacc tcttcagctt ccgcaaccac ggcgattttc atgaagactg
      421 cgtcaacatc atcatgaaag acctcattgc cctgatggat ccgaaataca tcgaagtatt
      481 cggcgagttc acaccgcgcg gcggcatcgc cattcatcct ttcgccaatt acggcaaagc
      541 aggcaccgag tttgaagcat tggcgcgtaa acgcctgttt gagcacgacg cacaataaac
      601 catccttccc atatttcaga cggcattcct tcgatacgat atgccgtctg aacgcctttc
      661 cgaaagattt ttatgtacgc atttaccgac gcacagcaac agaaggcact cttctggctg
      721 gtgctttttc atatcctcat catcgccgcc agcaactatc tggtgcagtt ccccttccaa
      781 attttcggca tccacaccac ttggggcgcg ttttcctttc ccttcatctt cctcgccacc
      841 gacctgaccg tccgcatttt cggttcgcac ttggcacggc ggattatctt ttgggtcatg
      901 ttccccgccc ttttgctttc ctacgtcttt tccgttttgt tccacaacgg cagttggacg
      961 ggcttgggcg cgctgtccga attcaacacc tttgtcggac gcatcgcgct ggcaagtttt
     1021 gccgcctacg cgctcggaca aatccttgat atttttgtgt tcaacaaatt acgccgtctg
     1081 aaagcgtggt gggttgcccc gactgcatca accgtcatcg gcaacgcctt agatacgttg
     1141 gtatttttcg ccgttgcctt ctacgcaagc agcgatggat ttatggcggc aaactggcag
     1201 ggcatcgctt ttgtcgatta cctgttcaaa ctcaccgtct gcggtctgtt tttcctgccc
     1261 gcctacggcg tgattctgaa tctgctgacg aaaaaactga cgaccctgca aaccaaacag
     1321 gcgcaagacc gccccgcgcc ctcgctgcaa aatccgtaaa acagccctgc cggaaatcgg
     1381 gacggttggg ttttctttta tttgcaaaca ctgtcggaac ggataaatcc gg
//
LOCUS       DAXIDM010000201         1432 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000201 DAXIDM010000000
VERSION     DAXIDM010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.201"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            130..1255
                     /locus_tag="ACFOAE_002064"
                     /pseudo
     CDS             130..1255
                     /locus_tag="ACFOAE_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250655.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT          385 a          346 c          336 g          365 t
ORIGIN      
        1 ggcaacgccg taccggtttt tgttaatcca ctataatacg caggcaaacc caagccttgc
       61 cggattgcag gatgaaaccc tgccgtagca gaccgcattt ccaatcctat aattcaaggt
      121 gtccgcctta tgaaaatcgt ttttatcaca acagtcgcat ccagcattta cggtttccgc
      181 gcccccatca ttaaaaaatt aatcggcaaa aaccatcagg tgtatgcctt tgtatcggag
      241 ttttccgaca atgaattgga tactatcagg gaaatggggg taacacccgt tacctaccgt
      301 tcaaaccgca gcgggctgaa cccgttttcc gatataaaat ccaccttcct catctttaaa
      361 gaactcaaaa aaatatcgcc ggatttggtt ttcccttatt tcgcaaaacc cgtgattttc
      421 ggcacttttg ccgcaaaact ggcaggcgtg cccagaatcg tcgggatgct ggaaggtttg
      481 ggattcgcat ttaccccgca gccggaaggc ataccgttaa aaacaaaaat cataaagggg
      541 atcttgattg ccttataccg cattgccctg ccgatgttgg aaagcctgat tgtattaaac
      601 cccgacgaca aagacgaact gacggacaaa tacggcatca aaataaaaaa catccatatt
      661 ttgggcggaa tcggtctgga ttcgcggcaa tatccttatt ccgaggcgga tattcccgat
      721 gaaaaagaac ccgtaaaatt cctctttatc ggcagatttc tgaaagaaaa ggggattgat
      781 gattttattc gggcggcgga acaggttaag gacaaatacc ccgatacggt ttttaccgct
      841 ttgggcgcaa tcgacaaatc acgcgggggg gggcgatttg gaacggcttg ccgcccgcga
      901 tattatccgt ttccccggtt ttgtgaacaa tgtttccgaa gtgataaagg cgcatcatat
      961 attcgtattg ccgtcttata gggaaggcgt tccccgaagc actcaggagg caatggccgt
     1021 cggcagggca gtgattacga cggatgtccc cggatgcagg gaaacggtcg ccgacaaggt
     1081 caacggcttc ctgatcgaac cttggaatcc ccgcatcttg gccgaaaaaa tgatttattt
     1141 tatcgaaaac agggaagccg tccgcctgat ggggaatgca agttatgcga ttgccaaaga
     1201 taaattcgat gccgaaaaag tcgatttgaa attgctcgat attttgaagg cgtaaacaag
     1261 gctgcccgct tttgagtttc ggtcatttct gataaacctc cgtcattccc gccacacccc
     1321 cgtcattccc tcgaaagcgg gaattcaggt tcgtttagtt tcggtcattt ccgataaatt
     1381 cttgcaactt tgcgtttcta gattcccact ttcgtgggaa tgacgacgga gg
//
LOCUS       DAXIDM010000202         1400 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000202 DAXIDM010000000
VERSION     DAXIDM010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1400
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.202"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..107)
                     /locus_tag="ACFOAE_002065"
     CDS             complement(<1..107)
                     /locus_tag="ACFOAE_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFC6885460.1"
                     /translation="MSTFFQQTAQAMIAKHINRFPLLKLDRVIDWQPIE"
     gene            446..714
                     /locus_tag="ACFOAE_002066"
                     /pseudo
     CDS             446..714
                     /locus_tag="ACFOAE_002066"
                     /inference="COORDINATES: protein motif:HMM:NF017953.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase"
     gene            complement(804..1253)
                     /locus_tag="ACFOAE_002067"
     CDS             complement(804..1253)
                     /locus_tag="ACFOAE_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002214937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilin protein"
                     /protein_id="HFC6885461.1"
                     /translation="MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRA
                     ALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEGFCIRLNGIARGALDSKFMLKAV
                     AIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK"
BASE COUNT          437 a          302 c          243 g          418 t
ORIGIN      
        1 tgctcgatcg gctgccaatc aattacccgg tccaacttca atagcgggaa gcggttgatg
       61 tgtttggcaa tcatggcttg ggcggtttgc tggaagaagg tgctcatgag aaatctccta
      121 aatgtcttgg tgggaattta ggggattttg gggaattttg caaaggtctc cttatgtcta
      181 aaggtgcaaa catgccttaa attaccatag tggattaaat ttaaatcagg acaaggcgag
      241 gcaacgctgt actggtttaa atttaatcca ctatatattg cataggcaaa atacaagcct
      301 ataacgaatt ggaaacaaaa tgccgtctga aaacatcttc agacggcatt ataaaatctg
      361 ttcacctttt cagatgagta atgtacaccc ttatacaatt tttgctacta tgccccataa
      421 atccacggct aaagatatcc ttattatgtc ctatgattta tcgaaacgac ttgtaatcgg
      481 cttagcatca agtgccctat tcgacttatc cgaatcggat aatatattta gaatggaagg
      541 ggcagaaacc tataggcaat atcagaggga aaaacaaaac catcccctaa aaaaggcgtt
      601 gtctttccat ttattaaaaa acttctgtca atcaatgaaa taaacccaaa cgacccaacg
      661 attgggttta ttcttttatc cagaaacaat ccagatacag attacgagtc ataactatag
      721 gcttaatatt acacgatttt cattccatca aggcggaaaa ccgcacaaat actgaaacac
      781 tatcgatcga tttgtaaaca agcctactta agtaacttgc agtccttatc atttccttta
      841 aaataatcca gcccgtcact acacgaactg gcggacttct tgcaaataaa ggttactaga
      901 ttttcattca tcttaataat aaaaggattt ttatctttat ctatggctac cgccttcaac
      961 atgaatttac tgtctaaggc cccgcgcgcg attccattca aacggataca aaagccttct
     1021 gcctctttaa tcggcaaact tggccatttg gtagatgttt gtttaaatct cccattctgc
     1081 agataaaact tttccataaa atgtgcattt tctaacaagg ctgcccgcac tgcatttatc
     1141 tttgctttct caacataatt gcgatagctc ggataaacaa ttaaagcaag tacagacaat
     1201 atcaagacca ctgatattaa ttcaaccagc gtaaaccccc gattatcagt cattacttta
     1261 cttccaataa gaacagatta ttcaacatat ttctttgaac agacttacta tcccattcga
     1321 cagtatgcat atttcccact ctatttttta gcggccggta tagccggttt tgccgggcct
     1381 tttggtgcgg gtgcgccgac
//
LOCUS       DAXIDM010000203         1390 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000203 DAXIDM010000000
VERSION     DAXIDM010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1390
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.203"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>1390
                     /gene="frpC"
                     /locus_tag="ACFOAE_002068"
     CDS             <1..>1390
                     /gene="frpC"
                     /locus_tag="ACFOAE_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated protein FrpC"
                     /protein_id="HFC6885462.1"
                     /translation="KDVNKNLGNGNTLAQQGSYTKTDGTTAKMGDLLLAADNLHSRFK
                     DKVELTAEQAKAANLAGIGRLRDLREAAALSGDLANMLKAYSAAETKEAQLALLDNLI
                     HKWAETDSNWGKKSPMRLSTDWTQTANEGIALTPSQVAQLKKNALVSLSDKAKAAIDA
                     ARDRIAVLDAYTGQDSNTLYYMSEEDALNIVKVTNDTYDHLAKNIYQNLLFQTRLQPY
                     LNQISFKMENDTFTLDFSGLVQAFNHVKETNPQKAFVDLAEMLAYGELRSWYEGRRLM
                     ADYVEEAKKAGKFEDYQKVLGQETVALLAKTSGTQADDILQNVGFGHNKNVSLYGNDG
                     NDTLIGGAGNDYLEGGSGSDTYVFGKGFGQDTVYNYDYATGRKDIIRFTDGITADMLT
                     FTREGNHLLIKAKDDSGQVTVQSYFQNDGSGAYRIDEIHFDNGKVLDVATVKELVQQS
                     TDGSDRLYAYQSG"
BASE COUNT          422 a          312 c          322 g          334 t
ORIGIN      
        1 aaagatgtaa ataaaaatct cggtaacggt aacactttgg ctcagcaagg cagctatacc
       61 aaaacagacg gtacaaccgc aaaaatgggg gatttacttt tagcagccga caatctgcac
      121 agccgcttca aagacaaagt ggaactcact gccgaacagg caaaagccgc caatcttgcg
      181 ggcattggtc gtctgcgcga tttgcgcgaa gctgccgcat tgtccggcga tttggccaat
      241 atgctgaaag cttattctgc cgccgaaact aaagaagcac agttggcatt gttagataat
      301 ttgattcaca aatgggcgga aaccgattcg aactggggca aaaaatcgcc aatgcgactt
      361 tcaaccgatt ggacgcaaac ggctaatgaa ggtattgcac tgacaccatc ccaagtagca
      421 caactaaaaa agaacgcttt agtttccctt tctgataaag ctaaagcagc tattgacgcc
      481 gcccgcgacc gcattgccgt gcttgatgcc tacacggggc aggattccaa cacactctat
      541 tacatgagcg aggaagatgc gcttaatatc gtcaaagtaa ccaacgatac atacgaccat
      601 ctcgccaaaa acatctacca aaacctgttg ttccaaaccc gtttgcagcc atatttgaat
      661 caaatcagtt tcaaaatgga aaatgatacg ttcactttgg attttagtgg tcttgttcaa
      721 gcatttaacc atgtcaaaga aactaatccg caaaaagctt ttgtggattt ggccgagatg
      781 cttgcatatg gcgaacttcg ttcttggtat gaaggccgaa gactaatggc cgattatgtg
      841 gaggaggcaa aaaaagcagg taaatttgaa gattaccaga aagtgttggg tcaggagacc
      901 gttgcattat tagctaaaac atcgggtacg caagcagatg atatcctgca aaatgtaggc
      961 tttggtcata ataaaaatgt ttctttatat ggtaatgacg gcaacgacac tctgatcggc
     1021 ggtgccggta atgattactt ggagggcggc agcggttcgg atacttatgt cttcggcaaa
     1081 ggcttcggtc aggatacggt ctataattac gactacgcta ccggacgcaa agacatcatc
     1141 cgctttaccg acggtattac agccgatatg ctgactttta cccgagaggg caaccatctt
     1201 cttatcaagg caaaagacga cagtggacaa gtgactgttc agtcctattt ccagaacgat
     1261 ggctcaggtg cttaccgtat cgatgagatt catttcgata acggcaaagt actggatgtt
     1321 gccactgtca aagaactggt acagcaatcc accgacggtt cggacagatt gtatgcctac
     1381 caatccggaa
//
LOCUS       DAXIDM010000204         1347 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000204 DAXIDM010000000
VERSION     DAXIDM010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.204"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(435..965)
                     /locus_tag="ACFOAE_002069"
                     /pseudo
     CDS             complement(435..965)
                     /locus_tag="ACFOAE_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611093.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT          383 a          332 c          281 g          351 t
ORIGIN      
        1 tccgcacgga aacctgcacc acgtcattcc tacgaaccta catcccgtca ttcccacaag
       61 gacagaaaac caaaatcaga aacctaaaat cccgtcattc ccacgaaagt gggaatctag
      121 aaatgaaaag caacaagcat ttatcgaaaa taactgaaac cgaacagact agattcccgc
      181 ctgcgcggga atgatgaatt catccgcacg gaaacctgca ccacgtcatt cccacgaacc
      241 tacattctgt cattcccacg aaagtgggaa tccaggattc agggacggag aaaccttttt
      301 tcccgataag tttccgcacc gaccggtcta gattcccgcc tgcgcgggaa tgacggttcg
      361 ggtatttctg acgattcatc gagccgtagc aactgtattt ttcaccccgt cgggcaaaaa
      421 taccaaaact caaatcaagc cgtccggata ccgttttcgg cggtatcgtt ttcggcggta
      481 tcgttttcgg caaaataatc acgcatccgg gcattcgata tcgtcagcag tttgcgcata
      541 catgccgtaa cggcaacctt atacggctta ccctcggaca gcaggcgttg gtagaaatcc
      601 cgaataagcg gttcaaaacg tgtcgctgcc acggtagcca tatacagcgc cttacgtacc
      661 gcagactttc cgccaaagca gcggcttttg aatttggttt ccccgctctc cctcgggtgc
      721 ggggcaatgc cggccaaact cgctatccgt ttgtgcgaca gccgccccaa ttcgggcagc
      781 atcgccatca gcgtagccgt cgttatcgaa ccgatgcctt tgatttgctc cgccacttgg
      841 gctttgccgt caaaatgcgt gtgggtgtgg tcgtcgattt gtttgtccaa ttcgtcaatc
      901 agccggtcaa aatgggcaat cagttgtttg acgcttccga cttgcgtttc atgaaactga
      961 tgcagatata gtggattaac aaaaatcagg acaaggcgac gaagccgcag acagtacaaa
     1021 tagtacggca acgctgtact ggtttaaatt taatccacta tattttgtaa tagctgccat
     1081 tatgcctact aggatatata ccttctatat aatccttatt taaataaaaa cccttataaa
     1141 aatctgtgtt atctgtcggg attgaaaaaa agattttatc tttctcatca ggtttatatt
     1201 tgctatcaat atcaaaaaga gaataaggat tacaatgagt tcgacatact aggtaaaaat
     1261 ttatatcttg gatcatgaaa tattcgatat ttatcaggat cgaaagatgc taaaaattca
     1321 tcaatatcgg tactggatat tttgtca
//
LOCUS       DAXIDM010000205         1317 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000205 DAXIDM010000000
VERSION     DAXIDM010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1317
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.205"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(107..1030)
                     /gene="lpxC"
                     /locus_tag="ACFOAE_002070"
     CDS             complement(107..1030)
                     /gene="lpxC"
                     /locus_tag="ACFOAE_002070"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008759 - UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine deacetylase activity [Evidence IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HFC6885463.1"
                     /translation="MLQRTLAKSISVTGVGLHSGERVALTLHPAPENSGISFHRTDLD
                     GEMGEQIKLTPYLINDTRLSSTIVTDKGVRVGTIEHIMSALSAYGIDNALIELNAPEI
                     PIMDGSSLPFIYLLQDAGVVDQKAQKRFLKILKPVEIKEAGKWVRFTPYDGFKVTLTI
                     EFDHPVFNRSSPTFEIDFAGKSYIDEIARARTFGFMHEVEMMRAHNLGLGGNLNNAIV
                     IDDTDVLNPEGLRYPDEFVRHKILDAIGDLYIVGHPIVGAFEGYKSGHAINNALLRAV
                     LADETAYDRVEFADSDDLPDAFHELNIRTCG"
     gene            1022..>1317
                     /locus_tag="ACFOAE_002071"
     CDS             1022..>1317
                     /locus_tag="ACFOAE_002071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885464.1"
                     /translation="MQHKPLPYQWGKFWNNTIKPEKQAMFFHSICQCIRFQYVSRIKM
                     YSGLTKIKTRRRTRLPPEKRKKCRPKTFRTAFSREPSFSQGHKTKTGNQKQQPK"
BASE COUNT          350 a          312 c          331 g          324 t
ORIGIN      
        1 taggttcgcg ggaatgacga attttaggtt tctgttttgg ttttttgtcc ttgtaggaat
       61 gatgaaattt tgagttttag gaatttaccg gaaaaaacag aaagcgttat ccacaagttc
      121 tgatgttcag ctcgtgaaat gcgtcgggca aatcatcgct gtcggcaaat tccacccggt
      181 cgtaagccgt ttcgtctgcc aaaaccgcgc gcaagagtgc gttgttgatg gcgtgtcccg
      241 atttgtagcc ttcaaacgcg ccgacaatcg gatgtccgac gatatacaaa tcaccgatgg
      301 catcaaggat tttgtggcgc acaaactcat cgggatagcg caagccttca ggattcagga
      361 catccgtgtc gtcaatcacg atggcgttgt tcaaattgcc gcccaaaccc agattgtggg
      421 cgcgcatcat ttccacttcg tgcataaagc cgaaagtgcg cgcgcgcgcg atttcgtcga
      481 tgtaggattt gccggcgaaa tcaatttcaa aagtgggcga gctgcggttg aaaaccggat
      541 ggtcgaattc gatggtcagc gttaccttaa agccgtcata cggcgtaaag cgcacccatt
      601 tgcccgcttc tttgatttcg acaggcttga ggattttcaa aaaacgcttt tgcgcctttt
      661 gatcgaccac gcccgcatct tgcaaaaggt aaataaacgg caggctggag ccgtccataa
      721 tcgggatttc gggtgcgttc agctcaatca gcgcgttgtc gataccgtag gcggacagcg
      781 cggacataat gtgttcgatt gtaccgacgc gcacgccttt gtcggtaacg atggtggagg
      841 aaaggcgggt atcgttgatc aaataagggg tcagtttgat ttgttcgccc atctcgccgt
      901 ccaaatcggt acggtggaag gaaatcccgc tgttttcagg cgcggggtgc agggtcagcg
      961 cgacgcgttc gcctgaatgc aacccgactc cggtaacgct gatggatttc gccaaagttc
     1021 tttgcagcat aaaccgctcc cttatcaatg gggtaagttt tggaataata cgataaaacc
     1081 ggaaaaacaa gctatgtttt tccatagtat ttgccaatgt atccgttttc aatacgtaag
     1141 ccgcataaaa atgtatagtg gattaacaaa aatcaagaca aggcgacgaa cccgcctccc
     1201 tcctgaaaaa cgcaaaaaat gccgtccgaa aacctttcgg acggcatttt cgcgtgaacc
     1261 gtcattctca caaggacata aaaccaaaac aggaaaccaa aaacagcaac ctaaaat
//
LOCUS       DAXIDM010000206         1201 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000206 DAXIDM010000000
VERSION     DAXIDM010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1201
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.206"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..913
                     /gene="mafA"
                     /locus_tag="ACFOAE_002072"
     CDS             <1..913
                     /gene="mafA"
                     /locus_tag="ACFOAE_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003691615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="adhesin MafA"
                     /protein_id="HFC6885465.1"
                     /translation="VLTACGTLTGIPAHGGGKRFAVEQELVAASSRAAVKEMDLSALK
                     GRKAALYVSVMGDQGSGNISGGRYSIDALIRGGYHNNPESATQYSYPAYDTTATTKAD
                     ALSSVTTSTSLLNAPAAALTKNSGRKGERSAGLSVNGTGDYRNETLLANPRDVSFLTN
                     LIQTVFYLRGIEVVPPEYADTDVFVTVDVFGTVRSRTELHLYNAETLKAQTKLEYFAV
                     DRDSRKLLIAPKTAAYESQYQEQYALWTGPYKVSKTVKASDRLMVDFSDITPYGDTTA
                     QNRPDFKQNNGKNPDVGNEVIRRRKGG"
     gene            917..>1201
                     /locus_tag="ACFOAE_002073"
     CDS             917..>1201
                     /locus_tag="ACFOAE_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010951299.1"
                     /note="MafB polymorphic toxins, described in Neisseria,
                     are fratricidal toxins the provide a competitive
                     advantage. Each MafB is accompanied by an immunity protein
                     MafI; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MafB family polymorphic toxin"
                     /protein_id="HFC6885466.1"
                     /translation="MKPLRRLTNLLAACAVAAAALIQPALAADLAQDPFITDNAQRQH
                     YEPGGKYHLFGDPRGSVSDRTGKINVIQDYTHQMGNLLIQQAAIQGNLGYT"
BASE COUNT          305 a          457 c          263 g          176 t
ORIGIN      
        1 cgtcctaacc gcctgcggca cactgaccgg catacccgcc cacggcggcg gcaaacgctt
       61 tgccgtcgaa caagaactcg tcgccgcatc gtcccgcgcc gccgtcaaag aaatggattt
      121 gtccgccctg aaaggacgca aagccgccct ttacgtctcc gttatgggcg accaaggttc
      181 gggcaacata agcggcggac gctactctat cgacgcactg atacgcggcg gctaccacaa
      241 caaccccgaa agtgccaccc aatacagcta ccccgcctac gacactaccg ccaccaccaa
      301 agccgacgcg ctctccagcg taaccacttc cacatcgctt ttgaacgccc ccgccgccgc
      361 cctgacgaaa aacagcggac gcaaaggcga acgctccgcc ggactgtccg tcaacggcac
      421 gggcgactac cgcaacgaaa ccctgctcgc caacccccgc gacgtttcct tcctgaccaa
      481 cctcatccaa accgtcttct acctgcgcgg catcgaagtc gtaccgcccg aatacgccga
      541 caccgacgta ttcgtaaccg tcgacgtatt cggcaccgtc cgcagccgta ccgaactgca
      601 cctctacaac gccgaaaccc ttaaagccca aaccaagctc gaatatttcg ccgtcgaccg
      661 cgacagccgg aaactgctga ttgcccctaa aaccgccgcc tacgaatccc aataccaaga
      721 acaatacgcc ctttggaccg gcccttacaa agtcagcaaa accgtcaaag cctcagaccg
      781 cctgatggtc gatttctccg acatcacccc ctacggtgac acaaccgccc aaaaccgtcc
      841 cgacttcaaa caaaacaacg gtaaaaaccc cgatgtcggc aacgaagtca tccgccgccg
      901 caaaggagga taaaccgtga aaccgctgcg cagactgaca aacctccttg ccgcctgcgc
      961 cgtagcggcg gccgcactca tacagcccgc cctcgcggcg gacttggcgc aagacccgtt
     1021 cattaccgat aacgcccaac ggcagcacta cgaacccggc ggcaaatacc acctcttcgg
     1081 cgacccgcgc ggcagcgttt ccgaccgcac cggcaaaatc aacgtcatcc aagactatac
     1141 ccaccagatg ggcaacctgc tcatccaaca ggcggcaatc caaggcaatc ttggttacac
     1201 c
//
LOCUS       DAXIDM010000207         1192 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000207 DAXIDM010000000
VERSION     DAXIDM010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.207"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            345..770
                     /locus_tag="ACFOAE_002074"
     CDS             345..770
                     /locus_tag="ACFOAE_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003711106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapD"
                     /protein_id="HFC6885467.1"
                     /translation="MSRYLITFDMDTNCLKDNYHGNNYTNAYSDIKTILARHGFENIQ
                     GSVYLGREGISEAHGTIAIQELTARFDWFYSCISNRLESDLNAQFIADGVYQAKQAFL
                     QRVEQLRISLTEAGLSDEQINQVLEKQKFELESPNLKLN"
BASE COUNT          363 a          280 c          249 g          300 t
ORIGIN      
        1 gcgagatcgg caatggcagc ggtactttgg ccgccgatat gcttaagttc agtaacctta
       61 cgccaccaaa acccttgcta gctaagggtt aaacagctca cttgaaatct acttaagtct
      121 aatctaaact atccaatatg gatagatttt taaacatagg gcaagcagca aaattattgt
      181 agctgaaagc acaatcactc gctggtggtc tcaaacacgt gccgactacc tcgccgaaaa
      241 cactatcagc cgcgataaac cgtgggaaaa gctcgttatc agccgccgca cttggtacta
      301 tcgcgggaaa ccgatgctgt ctgaaacgca acaggagaaa aataatgagc cgttacctga
      361 ttacctttga tatggatacc aactgcctga aagacaatta ccacggaaat aactatacca
      421 atgcctactc cgatattaaa accatcttgg ctagacatgg atttgagaac attcagggca
      481 gtgtttatct aggccgtgaa ggcatcagtg aagcacacgg aacaatagcc attcaggaac
      541 tgaccgctcg gtttgattgg ttttactcct gtatttcaaa ccgccttgaa agtgatttga
      601 acgcacaatt tatcgctgat ggtgtgtatc aagccaaaca ggctttcctt caacgtgttg
      661 aacaacttcg tatatcccta acagaagctg gattgtctga tgagcaaatc aatcaggttc
      721 tggaaaaaca gaaatttgaa ttggaaagtc ctaacctgaa attaaattaa cctcctttac
      781 tcaccaacat ccgccgcagc tctgtcagtt tttggcgcgc tgcggcgatt tctgtgcgtt
      841 ttagagcttc gggtagggtg tgaaacaact cactcgaaat ttacttaagt ctaatctaaa
      901 ctatccaagc agtaattagt acaaaaaagg caaacttatt ttaggagctt aaaattgcag
      961 ccgcgataaa ccgtgggaga gtctcggcat ttcccgcgcc acttggtaca aacgtggcaa
     1021 accgatgccg tctgaaaccg tacaacagga gacaaaataa tgcttgctca aatcgaactc
     1081 acaccctgcc agctaatggt ttacgtaact taaggttact ggatttacgc actaaggtta
     1141 ctgaacttaa gcatatcggc ggccaaagta ccgctgccat tgccgatctc gc
//
LOCUS       DAXIDM010000208         1191 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000208 DAXIDM010000000
VERSION     DAXIDM010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1191
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.208"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>1191
                     /locus_tag="ACFOAE_002075"
     CDS             <1..>1191
                     /locus_tag="ACFOAE_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC6885468.1"
                     /translation="ANAGSAALINTAVNGGSLKDNLEANILAALVNTAHGEAASKIKQ
                     LDQHYIVHKIAHAIAGCAAAAANKGKCQDGAIGAAVGEIVGEALVKNTDFSRMSATEI
                     EKSKAKITAYSKLVAGTASAVVGGDVNTAANAAQIAVENNTLYPRCVGAKCDEFQKEQ
                     QKWIRENPEEYREVLLLQTGFIPIIGDIQSFVQAQTAADHLFALLGVVPGIGESIQAY
                     KVAKAAKNLQGMKKALDKAATVATAQGYVSKTKIKIGQTELRVTAATDKQLLKAIGEG
                     RDTTGKMTEQLFDSLAKQNGFRVLSGGKYGGNNGFDHVWQAADGSVVLIVESKQIRNG
                     TVQLNPNGAGGYTQMSEDWIRQVLDQLPDGSPAKAAVFKANKNGTLKTAIAGVDRQTG
                     KAVIL"
BASE COUNT          362 a          226 c          325 g          278 t
ORIGIN      
        1 gccaatgcgg gcagtgccgc actgattaat accgctgtca acggcggcag cctgaaagac
       61 aatctggaag cgaatatcct tgcggctttg gtgaatactg cgcatggaga agcagccagt
      121 aaaatcaaac agttggatca gcactacata gtccacaaga ttgcccatgc catagcgggc
      181 tgtgcggctg cggcggcgaa taagggcaag tgtcaagacg gtgcgatagg cgctgcagtc
      241 ggtgagattg ttggtgaggc tttggttaag aatactgatt tcagtcgtat gagtgcgacc
      301 gaaatcgaaa aatctaaagc gaagattact gcctattcaa aactggttgc cggcactgcg
      361 tctgccgttg taggcgggga tgtgaataca gcggcgaatg cggcacagat agcggtggag
      421 aataatactt tgtatcctag atgcgttggt gcaaagtgtg atgaatttca aaaggaacaa
      481 caaaaatgga tacgtgaaaa tcctgaagaa tatcgagaag ttttgcttct tcagacagga
      541 tttattccaa ttatcggtga tatacagagt tttgtacaag cacagaccgc tgccgatcac
      601 ctgtttgctt tgctgggtgt ggttccgggt atcggtgaat cgatacaggc ctataaagta
      661 gcgaaagcgg caaaaaattt acaaggcatg aaaaaagcct tggacaaggc agcaaccgtt
      721 gccactgcac agggctatgt cagtaaaacc aaaatcaaaa tcggtcaaac tgaattaagg
      781 gttactgcag caactgacaa acaattgctg aaagctattg gcgaaggaag ggacacgaca
      841 ggtaaaatga ccgagcagtt atttgactct ttagctaaac aaaatggctt cagagtgctt
      901 tcgggcggca aatacggcgg aaataacggt tttgatcatg tatggcaggc tgccgatggt
      961 agtgtcgttt tgattgtaga aagtaagcag attaggaacg gtacggtaca gctgaatccg
     1021 aatggtgcgg gtggatatac gcaaatgagt gaggattgga ttagacaagt tttagatcaa
     1081 ttacccgatg gtagtcccgc taaagctgct gtcttcaaag caaataagaa cggcacatta
     1141 aaaacagcaa tagcaggcgt tgatcgtcaa acaggtaagg ccgttattct t
//
LOCUS       DAXIDM010000209         1159 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000209 DAXIDM010000000
VERSION     DAXIDM010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.209"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..474
                     /gene="mafB"
                     /locus_tag="ACFOAE_002076"
     CDS             <1..474
                     /gene="mafB"
                     /locus_tag="ACFOAE_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 3"
                     /protein_id="HFC6885469.1"
                     /translation="AGTVWRGKKVELNPTKWDWVKNNGYKKPAVRLMQTVDGEMAGGN
                     KPPKPSTQQHSTHSDNNIGLPAPYVKPDTSISPTGTIYVDSKGNAIPTPIGGYITGSP
                     DARFIQVRDSNGNLTGARIDDAHHANTHQDPRALTGHAHVPGVTNDDGTPWLPIK"
     gene            440..823
                     /locus_tag="ACFOAE_002077"
     CDS             440..823
                     /locus_tag="ACFOAE_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002224185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885470.1"
                     /translation="MMTEPHGYPSNNLPVKIINDIIYATQLVEDLVLGKIKIVDFLKS
                     YNNFYYWLGFDELPQSEKIKFLNYLNILSIHKEIQDKTVNRVYTDCFDIDKLHSLGRI
                     TTNECINGIKKIYQKNKLEFDNILK"
BASE COUNT          420 a          204 c          212 g          323 t
ORIGIN      
        1 gcaggtacgg tttggagagg taaaaaagta gaacttaacc cgaccaaatg ggattgggtt
       61 aaaaataacg gctataaaaa acctgctgtt cgccttatgc agactgtaga tggggagatg
      121 gctgggggaa ataagccacc gaaaccaagt acgcagcaac actctacaca ctctgataac
      181 aatataggct tacctgcccc atatgttaaa cctgatacat ctatttctcc gacaggaaca
      241 atttatgtag acagcaaagg aaatgcaata ccaacaccaa taggcggtta tataacaggt
      301 tcgcctgatg ctcgttttat ccaagtccga gatagtaatg gaaacttgac tggagccaga
      361 atagatgatg ctcatcatgc aaatacccat caagacccac gcgcacttac aggacacgca
      421 catgtaccag gagttacaaa tgatgacgga accccatggt tacccatcaa ataatttacc
      481 tgttaaaatc ataaatgata ttatttatgc aacccagtta gttgaagatt tggttttagg
      541 aaaaataaaa attgttgatt ttttaaaatc atataacaat ttttattatt ggcttggttt
      601 tgatgagtta cctcaatctg agaaaataaa atttctaaac tatctcaata tattaagtat
      661 tcataaggaa atacaagata aaactgtgaa tagggtttat accgattgtt ttgatattga
      721 taaattacat tcgcttggta gaattacaac taatgaatgt attaatggta taaaaaaaat
      781 ctatcaaaaa aacaaattag aatttgacaa tatactcaaa taactagcct atgttttgta
      841 aaataaaaat attcttgctg agtgtagagc cagagataaa aagatttgat agtagtttgc
      901 agttgtagaa ttatataaac aagaaaatag tcagcagccg taggtcagat tctcgaatcc
      961 gacattttcc aacagcggca tttcggaaac gatagatgcg tcaaatattt ttgtcggata
     1021 caaatatccg acctacatct ctgcgcagca aactttacaa ggtattaatg atttaggaaa
     1081 attaagtccg gaagcacaac ttgctgccgc gagcctatta caggacagtg ctttttacga
     1141 cacaaacctg atgcatcta
//
LOCUS       DAXIDM010000210         1147 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000210 DAXIDM010000000
VERSION     DAXIDM010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1147
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.210"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..585
                     /locus_tag="ACFOAE_002078"
     rRNA            <1..585
                     /locus_tag="ACFOAE_002078"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            682..795
                     /gene="rrf"
                     /locus_tag="ACFOAE_002079"
     rRNA            682..795
                     /gene="rrf"
                     /locus_tag="ACFOAE_002079"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            831..>1147
                     /locus_tag="ACFOAE_002080"
     CDS             831..>1147
                     /locus_tag="ACFOAE_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011798959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HFC6885471.1"
                     /translation="MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARC
                     GLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINAASQQELEALPGIGPAKAKAIAE
                     YRA"
BASE COUNT          278 a          257 c          334 g          278 t
ORIGIN      
        1 atagtgcaat ggcaaaaggt agcttaactg cgagaccgac aagtcgagca ggtgcgaaag
       61 caggacatag tgatccggtg gttctgtatg gaagggccat cgctcaacgg ataaaaggta
      121 ctccggggat aacaggctga ttccgcccaa gagttcatat cgacggcgga gtttggcacc
      181 tcgatgtcgg ctcatcacat cctggggctg tagtcggtcc caagggtatg gctgttcgcc
      241 atttaaagtg gtacgtgagc tgggtttaaa acgtcgtgag acagtttggt ccctatctgc
      301 agtgggcgtt ggaagtttga cgggggctgc tcctagtacg agaggaccgg agtggacgaa
      361 cctctggtgt accggttgta acgccagttg catagccggg tagctaagtt cggaagagat
      421 aagcgctgaa agcatctaag cgcgaaactc gcctgaagat gagacttccc ttgcggttta
      481 accgcactaa agagtcgttc gagaccagga cgttgatagg tggggtgtgg aagcgcggta
      541 acgcgtgaag ctaacccata ctaattgctc gtgaggcttg actctatcat ttgaagaact
      601 tcaagagata aaagcttact gactgattca gtcattaccg aatatattga ttaaggcttt
      661 accgatttgt aacagtttaa gtttggcggc catagcgagt tggtcccacg ccttcccatc
      721 ccgaacagga ccgtgaaacg actcagcgcc gatgatagtg tggttcttcc atgcgaaagt
      781 aggtcactgc caaacaccca ttcagaaaac ccccgattat tcgggggttt ttgctttgcc
      841 cggaaaaaat gtcggtgatg gcgggacggc atccgtacgg cgtccggtcg ggtttgcgga
      901 ggaacggctt gaaactttgg gatattcatt ttagaatgac tcgttttatc gtcgcaagat
      961 gcggtttatt gtttgcaacc cttaaaggaa aaaccatgaa gaaaatgttc gtgctgttct
     1021 gtatgctgtt ctcctgcgcc ttctcccttg cggcggtaaa catcaatgcg gcttcgcagc
     1081 aggagttgga ggcgctgccg ggcataggcc ctgcgaaggc gaaggccatt gcggaatacc
     1141 gtgcgca
//
LOCUS       DAXIDM010000211         1132 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000211 DAXIDM010000000
VERSION     DAXIDM010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1132
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.211"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(122..550)
                     /locus_tag="ACFOAE_002081"
     CDS             complement(122..550)
                     /locus_tag="ACFOAE_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFC6885472.1"
                     /translation="MGFEKVEHLLPDTVLDIVDVIGLAATEQLVKAIGGARFKFGKGK
                     VDTERLAILVEAIGEVKTHELLQVYGGEELYVPRCGKALIQLRNHRFYQEFVKLRDID
                     KESGLMAMTKLCPKYGISSRTGYMIINEMSRPAAQQAALF"
     gene            complement(531..965)
                     /locus_tag="ACFOAE_002082"
     CDS             complement(531..965)
                     /locus_tag="ACFOAE_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp16 family protein"
                     /protein_id="HFC6885473.1"
                     /translation="MRRALIAKIKIAQKELGLDDGTYRAVLERVTGKRSCADMDVSEL
                     ESVVADMRSHGFKPKAKGNPHGKPHLRRTSSAAMLDKVEALLTVGGKHWNYAHAMARR
                     MFGKDKVEYLDDTQLHKLVAALQIAENRKTEKAGGDDGVRKS"
BASE COUNT          300 a          338 c          203 g          291 t
ORIGIN      
        1 ttgaaaaccc cattaaaccg tctttaaccc atcgtcccga acggtagatg tttcatcccc
       61 tgcgaaccaa aaaaaagacc gtctgaatac agacggccaa agcctggtca cacatcactg
      121 cctaaaataa agctgcctgc tgtgccgcag gtcggctcat ttcattgata atcatatatc
      181 ccgttcgtga agagatgccg tatttagggc atagcttcgt catcgccata agcccgctct
      241 ccttatcaat atcgcgcaat ttgacaaact cctgataaaa cctatggttt ctcaactgta
      301 ttaacgcctt gccgcaccgt gggacataca attcctcgcc accatatacc tgcaacagct
      361 catgtgtttt cacttcgccg atggcttcga ccaaaattgc caaacgctcg gtgtccacct
      421 tgcccttacc aaatttaaac cgcgccccgc caatcgcctt gaccagctgt tccgtcgctg
      481 ccagtccgat gacatccaca atgtccaaca cggtatccgg caataaatgt tcaacttttt
      541 cgaaccccat catccccacc cgctttttcc gttttcctgt tttccgcaat ctgcaacgca
      601 gcaaccagtt tatgtagctg cgtatcgtct aaatattcga ccttatcctt accaaacatc
      661 cgccgcgcca ttgcgtgtgc atagttccaa tgtttgccgc cgacggtcag cagggcttcg
      721 actttgtcca acattgccgc tgatgatgtc cgacgcagat gtggtttacc gtgtgggtta
      781 ccttttgctt taggcttaaa tccgtgcgac cgcatatcag cgacaacaga ctcaagttcg
      841 gaaacatcca tatccgcaca cgaccgcttg cccgtcacgc gctccaacac cgcgcgatag
      901 gtaccgtcgt ccaagcccag ctccttttgg gcaattttaa tttttgcaat caacgcccgg
      961 cgcatctcaa acccataaaa cacaatatat tgactaatta acgcatatta taccaataaa
     1021 atacaatata tagtattaag ccgatgtttt ttgcgaaacg gacagacatg aaaaagcaac
     1081 tgtatttttc accccgtcgg gcaaaaatac caaaactcaa atcaagccgt cc
//
LOCUS       DAXIDM010000212         1037 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000212 DAXIDM010000000
VERSION     DAXIDM010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1037
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.212"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..932)
                     /gene="mafB"
                     /locus_tag="ACFOAE_002083"
     CDS             complement(<1..932)
                     /gene="mafB"
                     /locus_tag="ACFOAE_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002235291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymorphic toxin MafB class 3"
                     /protein_id="HFC6885474.1"
                     /translation="MKLPIQKFMMLFAAAISLLQIPISHANGLDARLRDDMQAKHYEP
                     GGKYHLFGNARGSVKNRVYAVQTFDATAVGPILPITHERTGFEGIIGYETHFSGHGHE
                     VHSPFDNHDSKSTSDFSGGVDGGFTVYQLHRTGSEIHPEDGYDGPQGSDYPPPGGARD
                     IYSYYVKGTSTKTKTNIVPQAPFSDRWLKENAGAASGFFSRADEAGKLIWESDPNKNW
                     WANRMDDIRGIVQGAVNPFLMGFQGLGVGAITDSAVNPVTYAAARKTLQGIHNLGNLS
                     PEAQLAAATALQDSAFAVKDSINSARQWADAHPN"
BASE COUNT          246 a          257 c          229 g          305 t
ORIGIN      
        1 atgttcggat gggcatcagc ccattgtctg gcagagttga tactgtcttt taccgcaaaa
       61 gcactgtctt gtaatgcggt tgcggccgca agttgtgctt ccggacttaa atttcctaaa
      121 ttgtgaatac cctgtaaagt tttccgtgct gccgcatagg ttaccgggtt taccgcactg
      181 tctgtaattg ccccaactcc caatccctga aaacccatta aaaaaggatt aaccgcacct
      241 tggacgatgc cgcgaatatc atccatacgg ttagcccacc aatttttatt ggggtcgctt
      301 tcccatatca gttttcctgc ttcatccgca cggctgaaaa aaccagaggc ggcaccggca
      361 ttttctttta gccaacggtc tgaaaatggg gcttgaggga caatattagt ctttgttttt
      421 gttgaagttc ctttgacata atagctgtat atatcccttg ctcctccggg gggcggataa
      481 tcgctgcctt gcggcccgtc atatccatcc tccggatgaa tttccgaccc tgtccgatga
      541 agttggtaaa cagtaaaacc accgtctaca ccgccgctga aatcagaagt gctttttgaa
      601 tcatgattat cgaacggact gtgtacttca tgtccatgtc ctgaaaaatg ggtttcataa
      661 ccgataatgc cttcaaaccc tgtccgttcg tgtgtaatag gcagtatggg gccgaccgca
      721 gttgcatcaa atgtctggac ggcgtaaacc cgatttttaa cactgccgcg agcattacca
      781 aacagatggt atttaccacc cggttcgtag tgttttgcct gcatatcatc gcgtaaacgg
      841 gcatccaaac cgttcgcatg actaatgggg atttgcagca acgatattgc cgctgcaaac
      901 agcatcatga atttttgaat aggcaatttc attttgtttt ccttggtagc aagcggttat
      961 ggtcgtgtga atcaaggttg cccttgtcta tgttgtcgca ctacttcatc gctgtatcca
     1021 tacccctcat gactgtt
//
LOCUS       DAXIDM010000213         1018 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000213 DAXIDM010000000
VERSION     DAXIDM010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1018
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.213"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(367..777)
                     /locus_tag="ACFOAE_002084"
     CDS             complement(367..777)
                     /locus_tag="ACFOAE_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002239379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885475.1"
                     /translation="MKIYNLDNIITSSALSLYKSTWVKLDLISCAKFIIEGTDFTFDW
                     DEGIENWIVFFHKNKVIGYLCAKLPFAILDNEQLKNQLYHKYPHVLTLQIKNIETEKI
                     SLNVNICRLTLCPSFHDEHDTLVCSVQDFYVNTV"
     gene            complement(781..>1018)
                     /locus_tag="ACFOAE_002085"
     CDS             complement(781..>1018)
                     /locus_tag="ACFOAE_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002240128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885476.1"
                     /translation="IDSKSLFKSDVDAEKATLDAARYADKHNLWDSQNKAKVPTNDVV
                     GYTDGKPTHIINIYRRKPNKDGIRPVHITPGKER"
BASE COUNT          315 a          182 c          151 g          370 t
ORIGIN      
        1 gagttacccg tatgattgcc gtatggtcgg atacttgtat ccgacaaaaa tatttgacgc
       61 gtctatcgtt tccgaaatgc cgctgttgaa aaatgtcgga ttcgagaatc cgacctacgg
      121 ttgctgaaca atgttttgta gaacttgctc aaaatccatg tttcgccatt ttcctttata
      181 tatacctaat acagcacggg ttacgatttc gtttaagtca taaatagcca tttacgtcct
      241 ctgctaattt tcagcgagta gattgggtta ccaaacccaa caaaaaagca gcctgaaaaa
      301 tttcaggatg cttgttttat gttttttatc aatgaattag gttttaatcc agcctgcgct
      361 tgctagttaa acagtattta cataaaaatc ttgtactgaa caaacaagcg tatcatgttc
      421 atcatgaaat gatgggcata acgttaatct acaaatgttt acatttaaag atattttttc
      481 agtttcaata tttttaattt gtaaggttaa tacatgagga tatttgtgat atagctgatt
      541 ttttaattgt tcgttgtcta atatagcaaa aggtaatttt gcacacaaat aaccaataac
      601 tttgttttta tgaaaaaaaa ctatccaatt ttcaattcct tcatcccaat caaaagtaaa
      661 atccgttcct tctatgataa atttagcaca agatattaaa tctaacttaa cccaagtgga
      721 tttatacaga ctcaatgctg atgaagttat aatattatct aaattataaa ttttcataaa
      781 tcaacgttcc ttacctggtg ttatatgcac aggtctaatc ccatctttat tcggctttct
      841 acgataaatg ttaattatat gtgtcggttt tccgtctgta tagccaacta cgtcgttcgt
      901 tggaactttt gccttatttt gactatccca taaattatgt ttatctgcat atctagcagc
      961 atctaatgta gctttttccg catcaacatc tgatttaaat aaacttttgc tatctatc
//
LOCUS       DAXIDM010000214         1015 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000214 DAXIDM010000000
VERSION     DAXIDM010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 1015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1015
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.214"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            33..395
                     /locus_tag="ACFOAE_002086"
     CDS             33..395
                     /locus_tag="ACFOAE_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFC6885477.1"
                     /translation="MNQLDQLGTRINLICNVFDKWIGQQDLNYNLFAVLYTLATEGSR
                     TQKHIGEKWSLPKQTVSGVCKTLAGQGLIEWQESEQDRRERLLSLTEKGKAHAAPLTE
                     SAQEFSDKETFAKFPKIP"
     gene            426..>1015
                     /locus_tag="ACFOAE_002087"
     CDS             426..>1015
                     /locus_tag="ACFOAE_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885478.1"
                     /translation="MSTFFQQTSQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQKTR
                     YLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNWLAQDNTLSELLKLINRQLTEKGLNIEKASAAVVDATIIQTAGSKQHQAIE
                     VDNKGQVSGQTTPSKDSDARWIKKNGLYKLGYKQHTR"
BASE COUNT          306 a          306 c          208 g          195 t
ORIGIN      
        1 ccgcacaaat ttagtcaata tcaagaccaa ttatgaacca actcgaccaa cttggcaccc
       61 gtatcaacct gatttgcaat gtcttcgaca aatggatcgg gcagcaggat ctgaattaca
      121 acctctttgc cgtactttat accctggcaa ccgaaggcag ccgcacgcaa aagcatatcg
      181 gcgaaaagtg gagcctgccc aaacagaccg tttcaggcgt atgcaaaacc cttgccggac
      241 aagggttgat tgaatggcag gaaagcgaac aggaccggcg cgaacggttg ctgtcgctga
      301 ccgaaaaagg caaagcccat gccgcacctt taacagaaag cgcgcaggaa ttcagcgaca
      361 aagagacctt tgcaaaattc cccaaaatcc cctaaattcc caccaagcca tttaggggat
      421 tttccatgag caccttcttc cagcaaacct cccaagccat gattgccaaa cacatcgacc
      481 gtttcccgct attgaagttg gatcaagtga ttgattggca gccaatcgaa caatacctga
      541 accgtcaaaa aacccgttac cttagagacc accgcggccg tcccgcctat cccctgttgt
      601 ccatgttcaa agccgtcctg ctcggacaat ggcacagcct ctccgatccc gaactcgaac
      661 acagcctcat cacccgcatc gatttcaacc tgttttgccg tttcgacgaa ctgagcatcc
      721 ccgattacag caccttatgc cgctaccgca attggctggc tcaagacaat accctgtccg
      781 aattgctcaa actgattaac cgccaactga ccgaaaaagg tctaaacata gagaaagcat
      841 ccgccgccgt tgttgacgcc accattattc agaccgccgg cagcaaacag caccaggcta
      901 tagaagtcga taacaaagga caagtcagcg gccaaaccac accgagtaaa gacagcgatg
      961 cccgttggat aaagaaaaac ggcctctaca aactcggtta caaacaacat acccg
//
LOCUS       DAXIDM010000215          999 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000215 DAXIDM010000000
VERSION     DAXIDM010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.215"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>999
                     /locus_tag="ACFOAE_002088"
     CDS             <1..>999
                     /locus_tag="ACFOAE_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002246826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
                     /protein_id="HFC6885479.1"
                     /translation="NTAHGEAASKIKQLDQHYIVHKIAHAIAGCAAAAANKGKCQDGA
                     IGAAVGEIVGEALTNGKNPDTLTAKEREQILAYSKLVAGTVSGVVGGDVNAAANAAEV
                     AVKNNQLSDKEGREFDNEMTACAKQNNPQLCRKNTVKKYQNVADKRLAASIAICTDIS
                     RSTECRTIRKQHLIDSRSLHSSWEAGLIGKDDEWYKLFSKSYTQADLALQSYHLNTAA
                     KSWLQSGNTKPLSEWMSDQGYTLISGVNPRFIPIPRGFVKQNTPITNVKYPEGISFDT
                     NLKRHLANADGFSQKQGIKGAHNRTNFMAELNSRGGRVKSETQTDIEGITRIKYEIP"
BASE COUNT          338 a          192 c          234 g          235 t
ORIGIN      
        1 aataccgcgc atggagaagc agccagtaaa atcaaacagt tggatcagca ctacatagtc
       61 cacaagattg cccatgccat agcgggctgt gcggcagcgg cggcgaataa gggcaagtgt
      121 caggatggtg cgataggtgc ggctgtgggc gagatagtcg gggaggcttt gacaaacggc
      181 aaaaatcctg acactttgac agctaaagaa cgcgaacaga ttttggcata cagcaaactg
      241 gttgccggta cggtaagcgg tgtggtcggc ggcgatgtaa atgcggcggc gaatgcggct
      301 gaggtagcgg tgaaaaataa tcagcttagc gacaaagagg gtagagaatt tgataacgaa
      361 atgactgcat gcgccaaaca gaataatcct caactgtgca gaaaaaatac tgtaaaaaag
      421 tatcaaaatg ttgctgataa aagacttgct gcttcgattg caatatgtac ggatatatcc
      481 cgtagtactg aatgtagaac aatcagaaaa caacatttga tcgatagtag aagccttcat
      541 tcatcttggg aagcaggtct aattggtaaa gatgatgaat ggtataaatt attcagcaaa
      601 tcttacaccc aagcagattt ggctttacag tcttatcatt tgaatactgc tgctaaatct
      661 tggcttcaat cgggcaatac aaagccttta tccgaatgga tgtccgacca aggttataca
      721 cttatttcag gagttaatcc tagattcatt ccaataccaa gagggtttgt aaaacaaaat
      781 acacctatta ctaatgtcaa atacccggaa ggcatcagtt tcgatacaaa cctaaaaaga
      841 catctggcaa atgctgatgg ttttagtcaa aaacagggca ttaaaggagc ccataaccgc
      901 accaatttta tggcagaact aaattcacga ggaggacgcg taaaatctga aacccaaact
      961 gatattgaag gcattacccg aattaaatat gagattcct
//
LOCUS       DAXIDM010000216          974 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000216 DAXIDM010000000
VERSION     DAXIDM010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.216"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(784..>974)
                     /locus_tag="ACFOAE_002089"
     CDS             complement(784..>974)
                     /locus_tag="ACFOAE_002089"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885480.1"
                     /translation="SDSPTPMPSEPSDGIFDAPAVYRRGAGVGKCPNRHSRQHRNLET
                     RHSRAGGNPDLSAQKLIG"
BASE COUNT          214 a          230 c          291 g          239 t
ORIGIN      
        1 aagattacgg tgttgtcggg aatgacgaat ccatccatac ggaaacctgc accacgtcat
       61 tcccacggaa gtgggaatct agaatctcgg ggtttcagtc atttccgata gattcccgcc
      121 gcgtcgtggg tctggattcc cacctgcgcg ggaatgacgg gtcttaagat tacggtgttg
      181 tcggacgggt ttcaagattg cggtgttgtc ggaacgcaac tgaaccgtca ttcccacgga
      241 agtgggaatc tagaatctcg gggttttagt catttccgat agattcccgc cgcgtcgggg
      301 ggctggattc ccgcctgcgc gggaatgacg aatttcgaga ttgcggtgtt gtcgggaatg
      361 acgaatccat ccatacgaaa acctgcacca cgtcattccc acggaagtgg gaatctagaa
      421 tctcgggggt ttcagtcatt tccgatagat tcccgccgcg tcaggggtct ggattcccgc
      481 ctgcgcggga atgacgaatt tcgagattac ggtgttgtcg ggaatgacga atccatccat
      541 acggaaacct gcaccacgtc attcccacgg aagtgggaat ctagaacgcg gggtttgagc
      601 aactgttttt atccgataag tttctgtgcg gacaggtcta gattcccgcc tgtgcgggaa
      661 tgacgaattt caagattacg gtgttgtcgg acgggtttcg agattacggt gttgtcggaa
      721 cgcaactgaa ccgtcattcc cacggaagtg ggaatctaga acgaggggtt tgagcaactg
      781 tttttatccg ataagtttct gtgcggacag gtctggattc ccgcctgcgc gggaatgacg
      841 ggtttcaaga ttacggtgtt gtcgggaatg acggttcggg catttcccta cgcccgcccc
      901 gcgcctgtaa acggcaggtg catcaaaaat gccgtctgaa ggttcagacg gcatcggtgt
      961 cggggaatca gaag
//
LOCUS       DAXIDM010000217          941 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000217 DAXIDM010000000
VERSION     DAXIDM010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.217"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..216)
                     /locus_tag="ACFOAE_002090"
     CDS             complement(<1..216)
                     /locus_tag="ACFOAE_002090"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885481.1"
                     /translation="MPSVELLLVIVGLPRGTFYYQLVVQSAEDKYADLKRHIHDIYQK
                     QLKDNGLVQSMSRKGNCLDNAAMESFFG"
     gene            complement(413..526)
                     /locus_tag="ACFOAE_002091"
     CDS             complement(413..526)
                     /locus_tag="ACFOAE_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002219744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFC6885482.1"
                     /translation="MSQKAAADQLNLPDCSILLQWLRLYHLNGINGLKPKP"
BASE COUNT          222 a          229 c          205 g          285 t
ORIGIN      
        1 tccgaagaaa ctttccattg ccgcattgtc caagcagttt cccttgcggg acatactctg
       61 aaccagaccg ttgtctttca actgcttttg ataaatatca tggatatgcc gtttcaaatc
      121 ggcatatttg tcttctgccg attggacaac caattggtaa tagaaggtgc cgcgtggcag
      181 tccgacaatc accaacagca gttcaacgga tggcattgcc ttaaccctgc gacgagttgc
      241 gttctttcta ccgcacttct ttcccataga ttaaggcatc gagctttttt agggcagcca
      301 tttccgcttt aaggcaagcc aattccgcaa gcagttcttc cttggttttc agatagtcgg
      361 ctttttcgtt tccggcggat gctgtttttt cacgggcttt cttcctttgg gtttagggtt
      421 tgggctttaa accgttaata ccattcaaat ggtagaggcg caaccattgc agcaagatgg
      481 agcagtcggg caaattcagt tggtctgcgg cagctttttg ggacattccc taccccgtca
      541 ccaggcggat tgcctcaagt ttgtattcga ccgaatattt tgtcgtatgc tttctacgtt
      601 tgatgccact ctctccgtgt aatctgtatt ttgtcaccca tctgcgtacc aatgaatcgg
      661 aaatagaaag atggtctgct gttccctgcc aaatagtatt gaacgacggc aagtcggaat
      721 tcatctgaat attttgccat aaaaaactgc accccctaaa gtcggtaagg tgtccaactt
      781 ttggggtgca gttcagaagc ggtctttttt tgcctgccgg ttttgaatca tcctccgtgt
      841 atattccctt gacgaaaaaa atgatgatat tacggatacc aaaactaagg tcgtatccgc
      901 ccccctactc tccctaagca aagagatgaa acagcgtatc g
//
LOCUS       DAXIDM010000218          935 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000218 DAXIDM010000000
VERSION     DAXIDM010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.218"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..194)
                     /locus_tag="ACFOAE_002092"
     CDS             complement(<1..194)
                     /locus_tag="ACFOAE_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
                     /protein_id="HFC6885483.1"
                     /translation="MKITHCKLKKKVQKELLRFFVLEVTARSAADILDIHPNSAALFY
                     RKIRTVINHHLALAADEVFEG"
     gene            complement(314..520)
                     /locus_tag="ACFOAE_002093"
     CDS             complement(314..520)
                     /locus_tag="ACFOAE_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885484.1"
                     /translation="MFDGAKVVRRVEGNLWVFGMVALEKTCFKGQMPSENRFQTAFSV
                     YLKQTGKGSNILQSSYSHKRFIVN"
     gene            complement(676..855)
                     /locus_tag="ACFOAE_002094"
     CDS             complement(676..855)
                     /locus_tag="ACFOAE_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885485.1"
                     /translation="MFCIVVYRFRTFVRLKAGKHRNESTQRKCRLNMCSGGVLLGGIG
                     VERLKKGFRRSLGVW"
     gene            793..935
                     /locus_tag="ACFOAE_002095"
                     /pseudo
     CDS             793..935
                     /locus_tag="ACFOAE_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002237266.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
BASE COUNT          254 a          240 c          174 g          267 t
ORIGIN      
        1 ccctcaaaaa cctcatcggc agccaaggcc aaatgatggt tgataaccgt gcggatttta
       61 cggtagaaca gtgctgccga attgggatgg atatccaaaa tatcggcggc agaacgggcg
      121 gtaacttcca gtacaaaaaa acggagtagt tctttttgta cttttttctt taatttgcag
      181 tgtgttatct tcatatttct agggtaacat atctgctaat ctagtatagc ccctagttta
      241 aagctttgtt tcttaagtcc gcagagtatg ccatggttag accttcaaag ttgagtattg
      301 tactattttg tttttaatta actataaaac gcttgtgtga ataggaagac tgcagaatat
      361 tgctgccttt tcctgtttgc tttaaataaa cagaaaatgc cgtctgaaac cgattttcag
      421 acggcatttg tcccttaaaa cacgtttttt caagcgcgac cataccaaac acccacaggt
      481 tgccttccac ccttcgtaca acctttgctc catcaaacat ccacttccta aatactgatg
      541 tctgcttagg ttgaatcggc attcgtacga ttacggcaca ccgcctaatc tgtacctgcg
      601 tctgttgcgc ccaataccaa aggctacctg aaaatctccc aaacttttca ggtagcctta
      661 tcacgttttc gactgtcacc acacgcccaa agaccgcctg aaaccctttt tcagacgttc
      721 cactccgata ccccccaaca aaacgccgcc cgaacacatg ttcagacggc attttctttg
      781 cgtcgattca ttgcggtgtt tacctgcttt aaggcggaca aaggtgcgga agcggtaaac
      841 aacgatacag aacataatgc tacatatttt agccatttcc cttccaaaca aaaaagcacc
      901 gacggcggcc gatgcccctt cctttacagg ttccc
//
LOCUS       DAXIDM010000219          906 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000219 DAXIDM010000000
VERSION     DAXIDM010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.219"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(87..719)
                     /gene="mtrR"
                     /locus_tag="ACFOAE_002096"
     CDS             complement(87..719)
                     /gene="mtrR"
                     /locus_tag="ACFOAE_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012503796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux system transcriptional
                     repressor MtrR"
                     /protein_id="HFC6885486.1"
                     /translation="MRKTKTEALKTKEHLMLAALETFYRKGIARTSLNEIAQAAGVTR
                     GALYWHFKNKEDLFDALFQRICDDIENCIAQDAEDAEGGSWAVFRHTLLHFFERLQSN
                     DIYYKFHNILFLKCEHTEQNAAVIAIARKHQAIWREKITAVLTEAVENQDLADDLDKE
                     TAVIFIKSTLDGLIWRWFSSCERFDLGKTAPRIIGIMMDNLENHPDLRRK"
BASE COUNT          201 a          203 c          237 g          265 t
ORIGIN      
        1 tgtattttta gaagaaggct ttgtgtcatt ttgatgccgt ctgaaagggt ttgttcgttt
       61 cagacggcat tgctaccaag gcttgattat ttccggcgca ggtcgggatg gttttccaag
      121 ttgtccatca ttatcccgat gatgcgcggg gcggttttgc ccaaatcgaa acgttcgcag
      181 gaagagaacc accgccaaat cagcccgtcc aaggttgatt tgatgaagat aactgccgtt
      241 tccttgtcca aatcgtcagc caaatcctga ttttccaccg cttcggtcaa aacggcggta
      301 attttctcgc gccagattgc ctgatgcttg cgggcaatgg cgataacggc ggcgttttgc
      361 tccgtgtgtt cgcattttaa aaacaggatg ttgtggaatt tgtagtagat gtcgttgctt
      421 tgcagccgct cgaaaaagtg cagcagcgtg tggcggaata ccgcccaaga ccctccttcg
      481 gcatcttcgg catcttgcgc gatgcagttt tcgatgtcgt cgcagatacg ttggaacagc
      541 gcgtcgaaca agtcttcctt atttttgaaa tgccaataga gcgcgccgcg cgttacgccg
      601 gcggcttggg cgatttcgtt gagcgaggtg cgcgcaatcc ctttgcggta aaaggtttcc
      661 aaggcggcaa gcatcaggtg ttctttggtt ttcaaggctt cggttttggt ttttctcata
      721 atggcgtttt cgtttcgggt cggtttgatg agggcggatt ataaaaaaga ctttgtaacc
      781 atgcaatcgt gtatgtataa tgaaacccat gaaattgaga ctacatctca actttgaaaa
      841 caggcataac ctgctttgca acccgttcga acattcgggt atcaaagcag gcggttttta
      901 tatcct
//
LOCUS       DAXIDM010000220          903 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000220 DAXIDM010000000
VERSION     DAXIDM010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.220"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(67..846)
                     /locus_tag="ACFOAE_002097"
     CDS             complement(67..846)
                     /locus_tag="ACFOAE_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFC6885487.1"
                     /translation="MKLVRPQKISDQVLSVLEGRIVEGVYAEGGKIPPERVLAEEFGV
                     SRPSVRSALNVLVARQVLEARQGDGYYVSVKPQQDFLQSWQELLGKHSNWEQDVFDFS
                     CHIEGCMAALAAERRTDADLKRIGFWLEKFEEACESGNLEHQSEADVSFHQTIADAAH
                     NLLFSHLSGGLLKMLYRQTRSSLIYLNQEEDPRPKLMAQHRVLYEAISNRRPGEASEA
                     AKAHLNYVASSIMKDREYQSRNRHADTLAQNDLKRVQDWEV"
BASE COUNT          213 a          291 c          180 g          219 t
ORIGIN      
        1 cgtactggtt taaatttagt tcactatacc gatacatccg aatatgccag accgtctaaa
       61 cggtattcat acctcccaat cctgcacgcg cttcaaatcg ttttgcgcca aagtatccgc
      121 gtggcggtta cggctctgat attccctgtc tttcatgatg ctgcttgcca cataattcaa
      181 atgtgccttt gccgcctccg aagcctcgcc cggccgacgg ttcgatatcg cctcatacag
      241 cacgcggtgc tgcgccatca gtttcggacg cggatcttct tcctgattca gataaataag
      301 gctgctgcgc gtctgccggt acagcatttt caacaaaccg cccgacaaat ggctgaacaa
      361 caaattgtgc gccgcatccg caatcgtctg atggaagctg acatcggctt cgctctgatg
      421 ttccagattg ccgctttcgc acgcctcctc aaacttttca agccaaaacc caatccgctt
      481 caaatcggca tccgtccggc gttctgccgc caatgccgcc atacagccct cgatgtggca
      541 gctgaaatca aaaacatcct gttcccaatt ggaatgcttg cccaaaagct cctgccaact
      601 ttgcaaaaaa tcctgctgcg gcttgaccga aacataataa ccgtctccct gcctcgcttc
      661 caaaacctga cgggcgacca aaacattcaa tgccgacctg accgacgggc gggacacgcc
      721 gaactcttcc gccaaaacgc gttcgggcgg aatcttgccc ccttccgcgt aaaccccttc
      781 cacgatgcgg ccttccaata ccgacaatac ctgatcgctg attttctgag gccttaccag
      841 tttcatcact cctcctttat aaagattccc tgccgaaccc ttccgaaata tagtggatta
      901 aca
//
LOCUS       DAXIDM010000221          903 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000221 DAXIDM010000000
VERSION     DAXIDM010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.221"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..281)
                     /locus_tag="ACFOAE_002098"
     CDS             complement(<1..281)
                     /locus_tag="ACFOAE_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885488.1"
                     /translation="MFPDKYKLSLKENIFLAKKVLVAQIHNLSRFENCQTTLLQTEQI
                     IHGKNVASASLEDIQTILNLKRAYQYVISHISNGEPVDISLLKKINNIVA"
BASE COUNT          222 a          189 c          203 g          289 t
ORIGIN      
        1 gcaacaatgt tgttgatttt tttaaggagt gaaatatcga ccggttcgcc gtttgaaata
       61 tgcgaaatca catattgata ggcacgtttc aggttcaaga tggtttggat gtcttccagt
      121 gacgcggagg ctacattttt gccatggata atttgttcgg tctgcaataa ggtcgtctga
      181 caattctcaa aacggctgag gttgtgaatt tgggcaacca atactttctt tgccaaaaaa
      241 atattttctt tcaaactcaa cttgtatttg tcgggaaaca cgataattcc ttaaataatt
      301 aaagcagtac gttaaatcat catcttatca tcactttcgg ggtttatgtt gcatgcgtcc
      361 gttttctaat acggtttccc atcccgcgaa acgaggcgga gacctgtgca aaaaacctgt
      421 tcacgaaatt ttccgcatta acgatacgct gaaaatgcgc taaaaatgac tgtgtttgaa
      481 tatcggttga tttcatccgt ttgtgtaacc tcgcgccggt tttgtcatga ttttgcatta
      541 tagtgaatta aatttaaacc agtacagcgt tgcctcgcct tgccgtacta tctgtactgt
      601 ctgcggcttc gtcgccttgt cctgattttt gttaattcac tatatttttg tcatgcggat
      661 atttcacggg atgacaaaac gggcgcaaaa aagcccgatt ggaaaatccg aatcgggctt
      721 ttttgtgatg ttctgttcga tttgcgtact aactgccggc cggagcgtcc gcgcccggtt
      781 tggcaggtcg gattctcgaa tccgacggct atttgagatg gcaggctttt gtcggataca
      841 agtatccgac ctacggcttg cttttcgtca ttcccgcgaa agcgggaatc tagaatctcg
      901 gac
//
LOCUS       DAXIDM010000222          883 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000222 DAXIDM010000000
VERSION     DAXIDM010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..883
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.222"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..460)
                     /locus_tag="ACFOAE_002099"
     CDS             complement(<1..460)
                     /locus_tag="ACFOAE_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885489.1"
                     /translation="MSTFFQQTAQAMIAKHIDRFPLLKLDQVIDWQPIEQYLNRQRTR
                     YLRDHRGRPAYPLLSMFKAVLLGQWHSLSDPELEHSLITRIDFNLFCRFDELSIPDYS
                     TLCRYRNWLAQDDTLSELLKLINRQLTEKGLKIEKASAAVVDATIIQTAGS"
BASE COUNT          200 a          171 c          255 g          257 t
ORIGIN      
        1 tgctgccggc ggtttgaata atggtggcgt caacgacggc ggcggatgct ttctctattt
       61 ttaagccttt ttcggtcagt tggcggttga tcagtttgag caattcggac agggtgtcgt
      121 cttgcgccag ccagttgcgg tagcggcata aggtgctgta atcggggatg ctcagttcgt
      181 caaaacgaca aaacaggttg aagtcgatgc gggtgatgag gctgtgttcg agttcgggat
      241 cggagaggct gtgccattgt ccgagcagga cggctttgaa catggacaac aggggatagg
      301 cgggacggcc gcggtggtct ctgaggtaac gggttctttg acggttcagg tattgttcga
      361 tcggttgcca atcaatcacc tggtccaact tcaatagtgg gaaacggtcg atgtgtttgg
      421 caatcatggc ttgggcggtt tgctggaaga aggtgctcat ggaacatccc ctaaatgtct
      481 tggtgggaat ttaggggatt ttgggggatt ttgcaaaggt ctcaaaccgt ttttctcgat
      541 aagtttccgt gccgacagac ctggattccc actttcgtgg gaatgacggt ggaaaagttg
      601 ccgtgatttc ggataaattt tcgtaacgca taatttccgt tttacccgat aaatgcccgc
      661 aatctcaaat cccgtcattc cccaaaaaca aaaaatcaaa aacagaaata tcgtcattcc
      721 cgcgcaggcg ggaatctagg tctgtcggtg cggaaacgta tcggataaaa cggtttcttc
      781 agattttacg ttctggattc ccactttcgt gggaatgacg aattttaggt ttctgttttt
      841 ggttttctgt ttttgaggga atgatgaaat tttaagtttt agg
//
LOCUS       DAXIDM010000223          843 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000223 DAXIDM010000000
VERSION     DAXIDM010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.223"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            113..843
                     /locus_tag="ACFOAE_002100"
                     /pseudo
     CDS             113..843
                     /locus_tag="ACFOAE_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581361.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015288 - porin activity [Evidence IEA]"
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="opacity family porin"
BASE COUNT          235 a          235 c          168 g          205 t
ORIGIN      
        1 ttcatccgct atattgtgtt gaaacatcgc cacaaacctg atatagtccg ctcctgcaac
       61 atcattgaaa atctttcttt tttaatcagt taaaccgaat acggagtcga aaatgaatcc
      121 agcccccaaa aaaccttctc ttctcttctc ttctcttctc ttctcttctc ttctcttctc
      181 ttctcttctc ttctcttctc ttccgcagcg caggcggcaa gtgaagacgg cagccgcagc
      241 ccgtattatg tgcaggcgga tttagcttat gccgccgaac gcattaccca cgattatccg
      301 caagcaaccg gtgcaaacaa cacaagcaca gtaagcgatt atttcagaaa catccgtacg
      361 cattccatcc acccccgagt gtcggtcggc tacgatttcg gcggctggag gatagcggca
      421 gattatgcca gttacagaaa atggagcaac aataaatatt ccgtcaacac aaaagtgttg
      481 aaagaaaacc agggcaacag gataaaactg aagacggaaa atcagggaaa cggtacgttc
      541 cacgcctctt cttctctcgg cttatccgcc atttacgatt tcaaactcaa cgataaattc
      601 gataaattca aaccctatat cggtgcgcgc gtcgcctacg gacacgttaa acatcaggtt
      661 cattcggtgg aaacagaaac cacgatttat accactgcac caacgggagg cgctgcagtg
      721 ggaggcacta tcccaaacaa agcgattagc aaacctccct atcacgaaag caacagcatc
      781 agcagcttgg gtcttggtgt catcgccggt gtcggtttcg acatcacgcc caagctgacc
      841 ttg
//
LOCUS       DAXIDM010000224          805 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000224 DAXIDM010000000
VERSION     DAXIDM010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.224"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..743)
                     /locus_tag="ACFOAE_002101"
     CDS             complement(join(<1..524,524..743))
                     /locus_tag="ACFOAE_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002242698.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1301 family transposase"
                     /protein_id="HFC6885490.1"
                     /translation="MARTAITDNIWEQLQTTMKAHGCHQWKNDRTVMEAILWKLRTGA
                     PWRDIPIELGSWKTAYNRFNRWSKKGLWQKFFFDLRKEIDKEWVFIDGSYVRCHQHAS
                     GARRGFDRAIGQSRGGNTTKIHLCVDSHGNPLDFKVTGGNVHDGQVANDLIEVIQEAQ
                     YFIADKGYDSQEIRDKAIEHGMKAIIPKRKNAKKPNPDFDSYLYKLRHLVENAFARLK
                     QFRSIATRYEKLARNFKSMLYLACSIIHAK"
BASE COUNT          193 a          175 c          160 g          277 t
ORIGIN      
        1 cttagcatga ataatagagc aagccaagta aagcatcgat ttaaaattac gagctaattt
       61 ctcatagcga gtagcaatac tacgaaactg ctttaatcgt gcaaatgcat tctcgactaa
      121 gtggcgtaat ttataaaggt agctatcaaa atcagggtta ggtttcttgg catttttacg
      181 ctttggtata atagctttca taccgtgttc tatcgcttta tctctgattt cttgcgagtc
      241 ataccctttg tcagcgataa aatactgggc ttcttgtatg acttctatca agtcgtttgc
      301 aacttgaccg tcgtgcacgt tacccccagt gactttaaaa tcgagcggat ttccatgcga
      361 gtccacacat aggtgtattt ttgtcgtgtt tccgccacgg ctttgtccaa ttgctctatc
      421 gaaaccacgc cgagctccac ttgcatgttg atgacaccgt acataacttc cgtcgatgaa
      481 tacccattct ttgtcaattt cttttcgtag atcaaaaaaa aattctgcca caagcctttt
      541 ttagaccatc ggttaaagcg gttataagcg gttttccatg accctagctc aataggtatg
      601 tctcgccatg gtgcacctgt tcttagcttc catagtatgg cttccatcac ggtacggtcg
      661 ttcttccatt gatgacagcc gtgcgctttc atggttgttt gtaattgttc ccatatgttg
      721 tcagttattg cggttctcgc cattgtttgt gtttgcctat atttcgttgg aatatagggt
      781 taaaataggg ctcttttggg cttat
//
LOCUS       DAXIDM010000225          769 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000225 DAXIDM010000000
VERSION     DAXIDM010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.225"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            96..614
                     /locus_tag="ACFOAE_002102"
     CDS             96..614
                     /locus_tag="ACFOAE_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885491.1"
                     /translation="MKQMLLAVGVVAVLAGCGKDAGGYEGYWREKSDKKEGMIAVKKE
                     KGNYFLNKINVVTGKEESMLLSEKDGELSINTGIGEIPIKLSDDGKELYVERRQYVKT
                     DAAMKDKIIAHQKKCGQTAQAYLDARNALPSNQTYQQRQAAIEQLKRRFEAEFDELEK
                     EIKCNGKPTLLL"
BASE COUNT          235 a          152 c          213 g          169 t
ORIGIN      
        1 aatttaacca actatagttt ttgcaaatca atattgacaa gctgaaaaaa aaaaacaata
       61 tactcgctcg gtcttaatgt taacggagta tggaaatgaa acaaatgctt ttagccgtcg
      121 gcgtggtggc ggtgttggcg ggctgcggca aggatgccgg cggttacgag ggttattggc
      181 gcgaaaaatc ggacaaaaaa gagggtatga ttgccgtcaa aaaagaaaaa ggcaattact
      241 tccttaataa aatcaacgtg gttacaggta aggaagaatc tatgcttttg tctgaaaaag
      301 acggcgagct ttcgataaac acggggatag gggaaatccc gatcaaactt tccgacgacg
      361 ggaaagagct gtatgtcgaa cgcaggcagt atgtcaaaac cgatgcggcg atgaaggaca
      421 aaatcatcgc ccatcagaaa aagtgcggac aaacggcaca ggcatatctc gacgcgcgaa
      481 atgcgttgcc gtcaaaccaa acgtatcagc agcgtcaggc ggcgatcgag caattgaaac
      541 ggcggtttga agccgagttt gacgaattgg aaaaagaaat caaatgcaac ggcaaaccga
      601 cattgttgct ttagcagagg acaaccggga ggatgccgcc gtccgaatcg gacgtgcggt
      661 tttcgtaccg gtacgggcgg gcaggaatgt ccgctttttt tgttcggacg cgtttgaata
      721 cccgtttgat tccgtccgtt tgcaaagggt atttttgttc gggcggaaa
//
LOCUS       DAXIDM010000226          733 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000226 DAXIDM010000000
VERSION     DAXIDM010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..733
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.226"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..180
                     /locus_tag="ACFOAE_002103"
     CDS             <1..180
                     /locus_tag="ACFOAE_002103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885492.1"
                     /translation="PYWFLLIHYKSKETAISTTPPQAAAAKHIGCFSTHPLKNASYPS
                     ALPAPPDFAALPDAV"
     gene            complement(123..674)
                     /locus_tag="ACFOAE_002104"
     CDS             complement(123..674)
                     /locus_tag="ACFOAE_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002216205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885493.1"
                     /translation="MKVLSGWSGRKMWRVLSALPIGVVFFDLIYGFVLNVLQGLDLQR
                     AVPDLEGVLAVTPDIAFNSLQIVANGGMAAVVCFGLAVVFLLNRSVRRRQVLEIGVFR
                     MLGLVAVLAFSAPSVWEWANALPLLLKGADVVNTGNARYVLTALCMPFPAVSCVIGLV
                     GRFRLQTASGRAAKSGGAGKADG"
BASE COUNT          206 a          284 c          137 g          106 t
ORIGIN      
        1 ccgtactggt ttttgttaat ccactataaa agcaaagaaa ccgccattag cactacaccc
       61 ccccaagctg cggctgccaa acacatcggc tgcttctcga cgcacccgct gaaaaatgcg
      121 tcctatccgt ccgccttgcc cgcaccccct gactttgccg ccctgcccga tgccgtctga
      181 agcctgaacc gccccaccag cccgatgacg cacgacaccg ccggaaaggg catacacaaa
      241 gccgtcagca cataacgcgc attccccgta ttgaccacgt ccgcgccctt cagcagcagc
      301 ggcagcgcgt tcgcccactc ccacaccgac ggcgcactga acgccaatac cgccaccagc
      361 cccaacatcc ggaacacccc gatttccaac acctgccgcc gccgcaccga acggttgagc
      421 aaaaacacaa ccgccaaccc gaaacagacc accgccgcca taccgccgtt ggcgacaatc
      481 tgcaaactgt tgaatgcaat atcgggcgta accgccaaca cgccttccaa atccggcacg
      541 gcacgctgca aatccaaacc ctgcaacaca ttcaacacaa aaccgtagat caaatcaaaa
      601 aacaccacgc ctatcggcaa agcactcaaa acccgccaca tcttcctgcc cgaccaaccg
      661 ctcaaaactt tcattttacc cgaccacgca agccgccgaa caaaaaacaa ggggctgtcc
      721 tagataacta gga
//
LOCUS       DAXIDM010000227          713 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000227 DAXIDM010000000
VERSION     DAXIDM010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.227"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(50..541)
                     /locus_tag="ACFOAE_002105"
     CDS             complement(50..541)
                     /locus_tag="ACFOAE_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885494.1"
                     /translation="MKYRRFYRNGGTYFFTVVTNKRQKILTDDAVRLALRQAVMAVRE
                     RYPFEILAWVLMPDHLHTIWRLPDNDSAYSERWRQIKRHSQYLIGGNLRLWQKRFWEH
                     TIRDEADFSCHFDYLHFNPVKHGYVGQISDWRFSTFHRYVKQGIYPHNWGGGNADFSI
                     GYD"
BASE COUNT          200 a          169 c          159 g          185 t
ORIGIN      
        1 gatgctcttt cagttttccg taggtcggat tctcgaatcc gacattactt caatcatatc
       61 caatagaaaa gtccgcattg ccgccacccc aattatgcgg ataaataccc tgtttaacat
      121 aacggtgaaa cgtagaaaac cgccaatcag aaatttgtcc tacatagcca tgtttgaccg
      181 gattgaaatg cagataatca aaatggcagg aaaaatcggc ctcatcgcgg atagtatgtt
      241 cccaaaagcg tttttgccaa agcctgagat tgccgccgat taaatattgg ctgtgccgct
      301 tgatttgccg ccagcgttcc gaataagcag aatcattgtc cggcagccgc catatggtat
      361 gcagatgatc gggcatcaac acccatgcca aaatttcaaa cggataccgt tcgcgcaccg
      421 ccattaccgc ctgccgcaaa gccaaacgca ccgcatcatc ggtcaaaatc ttctgccgtt
      481 tattggttac aaccgtaaaa aagtaagtgc cgccattgcg gtaaaaacga cggtatttca
      541 tagtattatg ctcggaatga ttttgtaggt cggattcttg aattcgacat tttgggcatt
      601 gctgcaatgg attgcaatga tgggaatgtt aaaggttttg tcggatacaa gtatccgacc
      661 tacgcttgct gaaccgtcat tcccacggaa gtgggaatct agaacgcggg gtt
//
LOCUS       DAXIDM010000228          705 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000228 DAXIDM010000000
VERSION     DAXIDM010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..705
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.228"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            28..705
                     /locus_tag="ACFOAE_002106"
     CDS             28..705
                     /locus_tag="ACFOAE_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595-like element ISNme3 family transposase"
                     /protein_id="HFC6885495.1"
                     /translation="MKLKNKYQKFSKISEQKFREIIRCFALDLTASDTAKMTGISVRG
                     INPIFLKIRHRIAALCEQSSPLSGVVELDESYFGARRIRGKRGRGASGKTIVFGILKR
                     NGVVYTEIVPDASKASLIKVIRGHISADSEINTDGWKAYDGLVDMGYEKHYRVHHGSN
                     EFARGKQHINGIESFWSYTKGRLAKFHGISKEMFYLHLKETEFRFNHRHEDLGKILMK
                     MLRNNPI"
BASE COUNT          218 a          137 c          156 g          194 t
ORIGIN      
        1 catcaaaaaa cctgataagc tcctaatatg aaactaaaaa ataagtatca aaagttcagc
       61 aaaatttcag agcaaaagtt tagagaaata atccgctgtt tcgctcttga tttgaccgct
      121 tccgatactg ctaaaatgac cggcattagt gtacgcggta tcaatcctat tttcctgaaa
      181 atcagacaca ggattgctgc tctgtgcgaa caaagctcac cactgtccgg tgtggtcgaa
      241 ttagatgaat cttactttgg tgcgcgacgt atcaggggta agcgcggtcg cggagcgtca
      301 ggtaaaacca tcgtatttgg catactgaaa cgcaatggcg tggtctatac ggaaatcgtt
      361 cccgacgctt cgaaagcctc actaatcaag gtcatacgtg gtcacatatc tgctgacagt
      421 gaaatcaata ctgacggctg gaaagcatat gacggtcttg tcgatatggg ctatgagaag
      481 cattaccgtg tccatcatgg ttccaatgag tttgctcgag gaaagcaaca tatcaatggt
      541 attgaatctt tttggagtta tactaagggg cgtttggcta aatttcatgg tatttccaaa
      601 gagatgtttt atctgcatct caaagaaacg gagtttaggt ttaaccaccg gcatgaagat
      661 ttaggtaaaa tattaatgaa gatgcttcga aataacccaa tttaa
//
LOCUS       DAXIDM010000229          704 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000229 DAXIDM010000000
VERSION     DAXIDM010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.229"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT          183 a          132 c          189 g          200 t
ORIGIN      
        1 ttagaacaac agcaatattc aaagattatc tgaaagtccg ggattctgga tttccacttt
       61 cgtaggaatg acgtggtgca ggtttccgta cggatggatt cgtcattccc gcgcaggcgg
      121 gaatctagac cttagaacaa cagcaatatt caaaggttag ctgaagcttt agagattctg
      181 gattcccact ttcgtgggaa tgacgggatt ttaggtttct gattttggtt ttctgttttt
      241 gtgggaatga tgaaattttg agttttagga atttaccgga aaaaacagaa accgttctgt
      301 cgtcattccc gcgcaggcgg gaatccagac cttgggataa cagcaatatt caaaggttag
      361 ctgaagcttt agagattcta gattcccact ttcgtgggaa tgacggaatg taggttcgtg
      421 ggaatgacgt ggtgcaggtt tccgtgcgga tggattcgtc attcccgcgc aggcgggaat
      481 ctagacctta gaacaacagt aatattcaaa ggttatctga aagtccgaga ttctagattc
      541 ccactttcgt gggaatgacg ggatgtaggt tcgtgggaat ggcgcggtgc aggtttccgt
      601 atggatgggt tcgtcattcc cgcgcaggcg ggaatctaga cattcaatgc taaggcaatt
      661 tatcggaaat gactgaaact caaaaaactg gattcccgct ttcg
//
LOCUS       DAXIDM010000230          697 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000230 DAXIDM010000000
VERSION     DAXIDM010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.230"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..432
                     /locus_tag="ACFOAE_002107"
     CDS             <1..432
                     /locus_tag="ACFOAE_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002250632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly/adherence protein PilC"
                     /protein_id="HFC6885496.1"
                     /translation="TAILGINTADGGKLTKKSARPIVPDANKDVAQYSGHKKGTNGKS
                     IPIGCMEKNGGTVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRAG
                     KNNRCFSQKGVRTLLMNDLDSLDITGPMCGMKRISWREVFF"
BASE COUNT          192 a          173 c          185 g          147 t
ORIGIN      
        1 accgccattt tgggcatcaa taccgccgac ggcggcaagc tgaccaagaa aagcgcgcgc
       61 ccgattgtgc cggacgccaa taaggatgtc gcgcaatatt ccggtcataa gaaaggcacc
      121 aacggcaaat ccatccctat aggttgtatg gaaaaaaacg ggggaaccgt ctgcccgaac
      181 ggatatgttt acgacaaacc ggttaatgtg cgttatctgg atgaaaagaa aacagacgga
      241 ttttcaacaa cggcagacgg tgatgcgggc ggcagcggta tagaccccgc cggcaagcgt
      301 gccggcaaaa acaaccgctg cttctcccaa aaaggggtgc gcaccctgct gatgaacgat
      361 ttggacagct tggacattac cggcccgatg tgcggtatga aacgaatcag ctggcgtgaa
      421 gtcttcttct gatttgcacg cgaaaatgcc gtccgaaagg ttttcggacg gcattttttg
      481 cgtttttcgg gaggggcggg ttcgtaaaag gcgggctata gggtaggctt catctcgcca
      541 atctcactga atccatcaat ttccacaatt caattaaata ccgtcaaacc gatgccgtca
      601 ttcccgcgca ggcgggaatc cagacattca atgctaaggc aatttatcgg gaatgactga
      661 aactcaaaaa actggattcc cactttcgtg ggaatga
//
LOCUS       DAXIDM010000231          695 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000231 DAXIDM010000000
VERSION     DAXIDM010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.231"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>695
                     /locus_tag="ACFOAE_002108"
     CDS             <1..>695
                     /locus_tag="ACFOAE_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS110-like element ISNme5 family transposase"
                     /protein_id="HFC6885497.1"
                     /translation="LVVTESTGGLEIPAAKAIRRAGIAVIIANPRQTHQFAQSQPLTK
                     TDAKDAKMPAFFAQMTAQKEDSQTMPYQPPTEAEEVLEALVNRRNQPADMRTAEKNRL
                     HQVHETQVGSVKQLIAHFDRLIDELDKQIDNHTHTHFDGKDQVAEQIKGIGSITTATL
                     MAMLPELRRLSHKRIAGLAGIAPHPRESGETKFKSRCFGGRSAVRKALYMATVAATRF
                     EPLIRDFYQRLLS"
BASE COUNT          187 a          206 c          184 g          118 t
ORIGIN      
        1 cctcgtcgtg acggaaagta ctggcggtct cgaaatcccc gccgccaaag ccatccgccg
       61 agcaggcata gccgtgatta tcgccaaccc gcgtcagacg catcagtttg cccaatcgca
      121 gccgctgacc aaaaccgacg ccaaagatgc caaaatgccc gccttcttcg cacagatgac
      181 ggcacagaaa gaagattcgc aaaccatgcc ctaccaaccg cccaccgaag cggaagaagt
      241 gttggaagcc ttggttaacc gccgcaacca accggcggat atgcggactg ccgagaaaaa
      301 ccgtctgcat caggttcacg aaacgcaagt cggaagcgtc aaacaactga ttgcccattt
      361 tgaccggctg attgacgaat tggacaaaca aatcgacaac cacacccaca cgcattttga
      421 cggcaaagac caagtggcgg agcaaatcaa aggcatcggt tcgataacga cggctacgct
      481 gatggcgatg ctacccgaat tgaggcggct gtcgcacaaa cggatagcgg gtttggccgg
      541 cattgccccg cacccgaggg agagcgggga aaccaaattc aaaagccgct gctttggcgg
      601 aaggtctgcg gtgcgtaagg cactgtatat ggctaccgtg gcagcgacac gttttgaacc
      661 gcttattcgg gatttctacc aacgcctgct gtcca
//
LOCUS       DAXIDM010000232          652 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000232 DAXIDM010000000
VERSION     DAXIDM010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.232"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(51..536)
                     /locus_tag="ACFOAE_002109"
     CDS             complement(51..536)
                     /locus_tag="ACFOAE_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009349087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FxsA family protein"
                     /protein_id="HFC6885498.1"
                     /translation="MRFFGIGFLVLLFLEIMSIVWVADWLGGGWTLFLMAATFAAGVL
                     MLRHTGLSGLLLAGAAMRSGGRVSVYQMLWPIRYTVAAVCLMSPGFVSSVLAVLLLLP
                     FKGGAVLQAGGAENFFNMNQSGRKEGFSRDDDIIEGEYTVEEPYGGNRSRNAIEHKKD
                     E"
BASE COUNT          193 a          211 c          119 g          129 t
ORIGIN      
        1 tcaaaccgga aaaatgccgt ctgaaccttc agacggcatt ccattcacat ttattcgtct
       61 tttttgtgtt cgatggcgtt tcgggaacga ttgccgccgt aaggctcttc aaccgtatat
      121 tccccctcga taatatcgtc atcgcgggaa aagccctctt ttctgcccga ttggttcatg
      181 ttgaaaaaat tttccgcacc tcctgcctgc aacactgcac ctcccttaaa cggcagcagc
      241 agcaataccg ccaacaccga ggatacgaat cccggactca tcagacacac cgccgccacc
      301 gtataacgga taggccacaa catctgataa acggataccc tcccgccgct tctcattgcc
      361 gcacccgcca ataaaagacc ggacagcccc gtatgcctga gcatcagcac accggcggca
      421 aaggttgccg ccatcagaaa cagcgtccaa ccgccgccca gccaatcggc aacccacaca
      481 atcgacataa tctccaaaaa cagcagcacc aaaaaaccga taccgaaaaa tctcattgac
      541 cgtcatcctt atatttaagt aaacagcaaa ccgcccgaac aagactccaa gcgacctgcc
      601 tgtaaatgat tacaaaacca tgtgcttcaa gccgaaacaa tgtgaaatca cg
//
LOCUS       DAXIDM010000233          648 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000233 DAXIDM010000000
VERSION     DAXIDM010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.233"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..648
                     /locus_tag="ACFOAE_002110"
                     /pseudo
     CDS             1..648
                     /locus_tag="ACFOAE_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
BASE COUNT          191 a          194 c          145 g          118 t
ORIGIN      
        1 cgcctaccct ctgctgtcca tgttcaaagc cgtcctgctc ggacaatggc acagcctctc
       61 cgatcccgaa ctcgaacaca gcctcattac ccgcatcgat ttcaacctgt tttgccgttt
      121 tgacgaactg agcatccccg attacagcac cttatgccgc taccgcaact ggctggcgca
      181 agacgacacc ctgtccgaat tgctcaaact gattaaccga caactgaccg aaaaaggttt
      241 aaaaatagag aaagcatccg ccgccgtcat tgacaccacc attattcaga ccgctggcag
      301 caaacagcgt caggccatag aagttgacga agaaggacaa atcagcggcc aaaccacacc
      361 gagtaaggac aaagatgccc gttggatcaa gaaaaacggc ctctacaaac tcggttacaa
      421 acaacatacc cgtaccgatg cggaaggcta tatcgagaaa ctgcacatca cccccgccaa
      481 tgcccatgag tgcaaacacc tgccgccgtt gttagaaggg atagctgaag gtacgaccgt
      541 ctatgccgac aaaggctatg acagtgcgga aaaccgaaca tctggaagaa catcagttgc
      601 tggacggcat tatgcgcaaa gcctgccgca accgtctgct gtcggaag
//
LOCUS       DAXIDM010000234          622 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000234 DAXIDM010000000
VERSION     DAXIDM010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.234"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            147..293
                     /locus_tag="ACFOAE_002111"
     CDS             147..293
                     /locus_tag="ACFOAE_002111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885499.1"
                     /translation="MMRNGGNLSGITENERKSGQGGEAADSTDRTEPIHLVLEHLRES
                     FSLS"
     gene            complement(426..>622)
                     /locus_tag="ACFOAE_002112"
     CDS             complement(426..>622)
                     /locus_tag="ACFOAE_002112"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885500.1"
                     /translation="FRFLFLVFCPCGNDEILSFRNLSEKTETAPPSFPRRRESRISMP
                     QEFIGKNQNPSAVIPAKVGI"
BASE COUNT          186 a          140 c          147 g          149 t
ORIGIN      
        1 gcgggaatga cgaaaagcaa cctttccgcg tccttcccgc aaaagtggga atctaggaac
       61 tcaaagctgc aagaatttat cagaaacaac tggaactcaa aaaaactaga ttcccgcctg
      121 cgcgggaatg acgaagggtt aaagaaatga tgagaaacgg cggtaattta tcgggaataa
      181 ccgaaaacga acggaaatca ggacaaggcg gcgaagccgc agacagtacg gataggacgg
      241 aaccgattca cttggtgctt gagcacctta gagaatcgtt ctctttgagc taaggcgagg
      301 caacgacgta ctggtttttg ttcatccact ataacagcaa ccctgtcgcc gtcattcccg
      361 cgaaagcggg aatccagtcc gttcagtttc ggtcatttcc gataaattcc tgctgctttt
      421 catttctaga ttcccacttt tgcgggaatg acggcggaag ggttttggtt ttttccgata
      481 aattcttgag gcattgaaat tctagattcc cgcctgcgcg ggaatgacgg cggagcggtt
      541 tctgtttttt ccgataaatt cctaaaactt aaaatttcat cattcccgca aggacagaaa
      601 accaaaaaca gaaacctaaa at
//
LOCUS       DAXIDM010000235          599 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000235 DAXIDM010000000
VERSION     DAXIDM010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.235"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..299
                     /locus_tag="ACFOAE_002113"
     CDS             <1..299
                     /locus_tag="ACFOAE_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002218874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885501.1"
                     /translation="FLFVLVNTVKAMIENTDKSQLSELDKILDGVTSQELKLAYDFCQ
                     GKFGQAGFSYRRHPNYFYLSSLIATFPEFELSKTDRDYLKGIINFDNYLLYELD"
     gene            343..>599
                     /locus_tag="ACFOAE_002114"
     CDS             343..>599
                     /locus_tag="ACFOAE_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002260789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histone acetyltransferase"
                     /protein_id="HFC6885502.1"
                     /translation="MIELKLVDESSFQAVLDLKISEADERARFVAPNVRSLADAWLYR
                     ENEDVFPRAIYWDKQVVGFLLLEIDKDEAEYFIWRIMIGQQ"
BASE COUNT          188 a           90 c          129 g          192 t
ORIGIN      
        1 attttctttt tgttttagta aatacagtga aagctatgat agaaaatact gataaaagtc
       61 agctttcaga gttagataaa attttagacg gtgtcacaag tcaagaattg aaacttgcct
      121 atgatttttg tcaagggaaa ttcggtcaag caggtttttc ttatcgtagg cacccgaatt
      181 atttttattt gtccagttta attgcgactt ttccagaatt tgagttgtct aaaacagacc
      241 gagattacct caaaggaatc ataaattttg ataactacct tttatatgag ttagattagt
      301 ctttaatcac ctcaaaaccc tatttattca aaaggagaaa aaatgattga gctgaaatta
      361 gtagatgaga gcagttttca ggcagtgctg gatttgaaaa tatctgaagc tgatgaacga
      421 gcacgttttg tggctccaaa tgtacgctct ttagctgacg catggctcta ccgggaaaat
      481 gaagatgtgt ttccgagggc aatctattgg gataagcaag tggttggctt tctcctgctg
      541 gaaatagaca aggatgaagc agaatacttt atctggcgga taatgattgg tcagcagtg
//
LOCUS       DAXIDM010000236          599 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.236, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000236 DAXIDM010000000
VERSION     DAXIDM010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.236"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            172..465
                     /locus_tag="ACFOAE_002115"
     CDS             172..465
                     /locus_tag="ACFOAE_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002225931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885503.1"
                     /translation="MKTNDKLNRQIDVLQKQSAAIHNEAYIEMNTLLYRHREVVSVHN
                     RKADYAEKGKERIALFPRGLNGITKLPAAVLLPERPDCFDMKAVWQMFNRIPR"
BASE COUNT          159 a          151 c          159 g          130 t
ORIGIN      
        1 tccattcggc agggaaagcc tgaagaagaa ttttcccgca agatggccgg ctgcctaacc
       61 gacttggaaa actgtttgga aaaatacctc gaacagttcg ggccggtatc ggaaagtatc
      121 gaagcctgta ccgtcaaact gcaggagtaa ccgtcgttct tcaacaggct gatgaaaacc
      181 aacgacaagc tcaataggca gattgacgtg ttgcagaaac agtcggcagc catccacaac
      241 gaagcctata tcgaaatgaa cacgctgctt taccgccacc gcgaagtggt ttccgtccac
      301 aaccgcaagg cggattatgc ggaaaagggc aaagagcgga ttgcgctgtt cccgcgcggc
      361 ttgaacggca tcaccaagct gcctgccgcc gtcctgttgc ccgagcgtcc cgattgtttt
      421 gatatgaagg cagtttggca aatgtttaat agaataccga ggtaggcgta tcggctgccg
      481 gataaaaatg ccgtctgaaa cggaagcgtt cagacggcat tgttgcagtg gaacaaatca
      541 aaatgcaccc cgtcattcct gtctgtacgg tgatagcggc agtgttttcc tgcttcgtt
//
LOCUS       DAXIDM010000237          571 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.237, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000237 DAXIDM010000000
VERSION     DAXIDM010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.237"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT          150 a          139 c          135 g          147 t
ORIGIN      
        1 gcttcgccgc cttgtcctga tttttgttaa tccactatat gaatcgtcat tcccgcgcag
       61 gcgggaatct agacattcaa tgctaaggca atttattgaa aatgactgaa actcaaaaaa
      121 ctagattccc actttcgtgg gaatgacgtg gtgcaggttt ccgtacgaat ggattcgtca
      181 ttcccgcaca ggcgggaatc tagacattca atgctaaggc aatttatcgg gaatgactga
      241 aactcaaaaa actagattcc cactttcgtg ggaatgacgc ggtgcaggtt tccgtacgga
      301 taggttcgtc attcccgcgc aggcgggaat ctagacctgt cggtgcggaa acttatcgga
      361 taacacggtt tccccaaccc tgcatcctgg attcccactt tcgtgggaat gacggcggag
      421 cggtttctgc tttttccaat aaatgccccc caaactaaaa tccgtcattc ccgcgcaggc
      481 gggaatctag acattcaatg ctaaggcact ttatcgggaa tgactgaaac tcaaaaaact
      541 ggattcccac tttcgtggga atgacgggat g
//
LOCUS       DAXIDM010000238          549 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000238 DAXIDM010000000
VERSION     DAXIDM010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.238"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>549
                     /locus_tag="ACFOAE_002116"
     CDS             <1..>549
                     /locus_tag="ACFOAE_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004467674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gliding motility protein"
                     /protein_id="HFC6885504.1"
                     /translation="ADAGDVYCVYNIRLKQYTACQVTRVEEHGGKKAYATLLALDWQG
                     NKPLGAAELADLKPLYKDFMYWERGLHMYKASAVVPTGYVRVGNTAPLVGEDTQRYAS
                     FWGDGYDVYRQLRWQQIPEKQRKAFKKAAKSKKTVMFAGREYGISKQNLSDVWDDFED
                     AMELKAFPCLSSLFLTKWHKNLY"
BASE COUNT          151 a          121 c          159 g          118 t
ORIGIN      
        1 gctgatgccg gagacgtata ttgcgtctat aacatcagac tgaagcagta cactgcctgc
       61 caggttaccc gagttgaaga acacggtggg aaaaaagcat atgcaaccct gctggctttg
      121 gactggcagg gcaacaaacc gcttggggcg gcggagctgg cggatttgaa accgctttac
      181 aaagacttta tgtattggga acgcggtctg cacatgtata aggcaagtgc cgtcgtgccg
      241 acgggatatg tacgggttgg gaataccgcg ccgctggtcg gcgaagacac gcaacggtat
      301 gcctcttttt ggggcgacgg ctacgacgtg taccgtcagt tgagatggca gcagataccc
      361 gaaaaacaga gaaaggcatt caaaaaagcc gccaaaagca aaaagaccgt gatgtttgcc
      421 ggacgggaat acggcatatc caaacagaat ttgagcgatg tttgggatga ttttgaagac
      481 gcgatggaac tgaaggcgtt tccctgcctg tcttcgctgt ttctgaccaa atggcataaa
      541 aatctatat
//
LOCUS       DAXIDM010000239          541 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000239 DAXIDM010000000
VERSION     DAXIDM010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.239"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..300
                     /locus_tag="ACFOAE_002117"
     CDS             <1..300
                     /locus_tag="ACFOAE_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885505.1"
                     /translation="KGYDGAENRQHLEEHQLLDGIMRKACRNRPLSETQTKRNRYLSK
                     TRYVVEQSFGTLHRKFRYARAAYFGLLKVSAQSHLKAMCLNLLKAANRLSAPAAA"
BASE COUNT          132 a          122 c          163 g          124 t
ORIGIN      
        1 aaaggctacg acggtgcgga aaaccggcaa catctggaag aacatcagtt gttagacggc
       61 attatgcgca aagcctgccg caaccgtccg ctgtcggaaa cgcaaaccaa acgcaaccgg
      121 tatttgtcga agacccgtta tgtggttgaa cagagcttcg gtacgctgca ccgtaaattc
      181 cgctatgcgc gggcagccta tttcgggctg ctcaaagtga gtgcgcaaag ccacctgaaa
      241 gcgatgtgtt tgaacctgtt gaaagcggcc aacaggctaa gtgcgcccgc tgccgcctaa
      301 aaggcagccc ggatgcctga ttatcgggta tccggggagg attaaggggg cgtttgggta
      361 gaattaggag gtatctgggg cgaaaacagc cgaaaacctg tgtttgggtt tcggctgtcg
      421 ggagggaaag gaattttgca aaggtctcgg actttcagat aatctttgaa tattgctgtt
      481 gttctaaggt ctagattccc gcctgcgcgg gaatgacggt tcagttgcta cggttattgt
      541 c
//
LOCUS       DAXIDM010000240          522 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000240 DAXIDM010000000
VERSION     DAXIDM010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.240"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(161..463)
                     /locus_tag="ACFOAE_002118"
                     /pseudo
     CDS             complement(161..463)
                     /locus_tag="ACFOAE_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0009289 - pilus [Evidence IEA];
                     GO_process: GO:0007155 - cell adhesion [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
BASE COUNT          106 a          112 c          144 g          160 t
ORIGIN      
        1 attttaggtt tctgtttttg gttttatgtt cttgtgggaa tgatgaaatt ttaagtttta
       61 ggaatttatc ggaaaaaaca gaaaccgctc cgccgtcatt cccgcgcagg cgggaatcca
      121 gcctcgtcgg tgcggaaact tatcgggtaa aaaggtttct ctagtttggt gtcgattttc
      181 ttgtcggtgc tgttgacggc aggtgcttgg tgtcgatttc gttgccggtg actttgttaa
      241 cggcgtcggc gctggcgttg ggggcgtcgc gcgtaaccgg ctgtccgcag aaccatttta
      301 ccgaaccgtc ttgacgcttg gcccacagag agagtttttt gcctttgatt tcgttgttta
      361 cgttgcttga agccatttgg gcggtaatga cgccgtttgc gacttcaact ttctcaacat
      421 atttgccttt gatgtcggag ggggaggatg ccacgccggc ggcatcatta aatcccgtca
      481 ttcccacgaa agtgggaatc tagaacgcaa aatctcaaga aa
//
LOCUS       DAXIDM010000241          490 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000241 DAXIDM010000000
VERSION     DAXIDM010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.241"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(123..>490)
                     /locus_tag="ACFOAE_002119"
     CDS             complement(123..>490)
                     /locus_tag="ACFOAE_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010980934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="calcium-binding protein"
                     /protein_id="HFC6885506.1"
                     /translation="GFGQDTVYNYHVDKNSDTMHFKGFKAADVHFIRSGSDLVLSASE
                     QDNVRISGFFYGENHRVDTFVFDDAAISNPDFAKYINAGNNLVQSMSVFGSNTAATGG
                     NVDANTQSVQQPLLVTPSA"
BASE COUNT          155 a          103 c           88 g          144 t
ORIGIN      
        1 aatttcgtta acagactatt tttgcaaagg tctcgaccct tatcccaata ttaagaaaaa
       61 cagcaatcaa aataaacttg attgctgttt ttcagtttaa gccatgaatg tgattaagct
      121 ccttatgcag atggcgttac caataacggc tgctgtacgg attgtgtatt ggcatccaca
      181 tttcctcctg tcgcagcagt attagaaccg aacacagaca tagactgtac caaattattg
      241 ccagcattaa tatacttggc aaaatctgga ttactgatag ctgcatcatc aaagacaaat
      301 gtatctacac gatggttttc accatagaag aatccggaaa tacgtacgtt gtcttgttca
      361 gaagcgctaa gcaccaaatc acttccggaa cggataaaat gaacatctgc tgctttaaat
      421 cctttaaagt gcatagtgtc agagttttta tccacatggt agttatagac cgtatcctga
      481 ccgaagcctt
//
LOCUS       DAXIDM010000242          483 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000242 DAXIDM010000000
VERSION     DAXIDM010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.242"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..346
                     /locus_tag="ACFOAE_002120"
                     /pseudo
     CDS             1..346
                     /locus_tag="ACFOAE_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981065.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
BASE COUNT          147 a          142 c          109 g           85 t
ORIGIN      
        1 aaaatcagcc gttaccgagt attacctgaa tcacggcaaa tggcctgacg gcaacagtga
       61 taccggcgtg gcaacctcct ctgaaatcaa aggcaaatat gttaaggaag ttacagtcgc
      121 aaacggcgtc gttaccgccg aaatgaaatc aagcggcgta aacaacgaaa tcaaaggcaa
      181 aaaactctcc ctgtgggcca agcgtcaaaa cggttcggta aaatggttct gcggacagcc
      241 ggttgagcgc accgacaccg ccaccgacac cgccgttacc gccgccaacg acaaaaagat
      301 cgacaccaag tacctgccgt caacctgccg cgacgcttca tctgccagcc gtacaaaaac
      361 acccggtttc gctttcaaat acttccaaaa aatcagccgt taccgagtat tgcccgaatc
      421 acggcaaatg accaaaaaac ttcgtcattc ccgcgcaggc gggaatctag gtttgtcggc
      481 gca
//
LOCUS       DAXIDM010000243          460 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000243 DAXIDM010000000
VERSION     DAXIDM010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.243"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            138..460
                     /locus_tag="ACFOAE_002121"
                     /pseudo
     CDS             138..460
                     /locus_tag="ACFOAE_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002233337.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin"
BASE COUNT          139 a          127 c          107 g           87 t
ORIGIN      
        1 atccagaacg caaaatctca agaaaccgtt ttcccgataa gtttccgtca agaaaatcga
       61 caccaaacta gagaaacctt tttacccgat aagtttccgt accgacgagg ctggattccc
      121 gcctgcgcgg gaatgacgaa gctatccttt tggctgaagg tcaaaaatca gccgtcaccg
      181 agtattacct gaatcacggc atatggcccg gcgacaacag ttctgccggc gtggcaacct
      241 cctctaaaat caaaggaaaa tatgttaagg aagttacagt cgcaaacggc gtcgttaccg
      301 ccacaatgct ttcaagcggc gtaaacaaag aaatccaagg caaaaaactc tccctgtggg
      361 ccaagcgtca agacggttcg gtaaaatggt tctgcggaca gccggttacg cgcgacgcca
      421 acgccagcgc cgacgccgtt aacaaagtca ccggcaacga
//
LOCUS       DAXIDM010000244          452 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000244 DAXIDM010000000
VERSION     DAXIDM010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.244"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(12..224)
                     /locus_tag="ACFOAE_002122"
     CDS             complement(12..224)
                     /locus_tag="ACFOAE_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019273370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFC6885507.1"
                     /translation="METLILDIGGMSCGGCVKSVTRILESVKGVASVEVSLENKSATV
                     GYDPAQTDAGALIEAVEDGGYDAALK"
BASE COUNT          101 a          121 c          117 g          113 t
ORIGIN      
        1 tttttgccgc tttatttcaa cgcggcatca tagccgccgt cttcaacggc ttcaatcaac
       61 gcccctgcat cggtttgcgc gggatcgtaa ccgacggtcg cacttttgtt ttcaaggctg
      121 acttcgacgc ttgccacgcc tttgacgctt tccagtatcc gggtaacgct tttgacgcag
      181 ccgccgcagc tcatgccgcc gatgtcgagg ataagggttt ccatcatttt cctttcgttg
      241 gaactgcaat ctgacgggcg ttattgtaag tcggggcgtg aacttgggca aacgcggaaa
      301 cggtgcggcg gtttggaaaa agacggacgc ttgcgcataa tggcggcaat tcccatcagg
      361 acgacaacaa tgaacgcttc gcaaaaaccc tggttgagca tcatcgcctt gacaatcggc
      421 gcatttatag tggattaaca aaaaccagta cg
//
LOCUS       DAXIDM010000245          437 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000245 DAXIDM010000000
VERSION     DAXIDM010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.245"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(207..>437)
                     /locus_tag="ACFOAE_002123"
     CDS             complement(207..>437)
                     /locus_tag="ACFOAE_002123"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885508.1"
                     /translation="DSHFRGNDEVEVTRNLKQAKPNEPDSHFRGNDGMQVSVWMDSSF
                     PRRRESRSVSAETYQVKRFLEILRPGFPLSWE"
BASE COUNT          111 a          108 c           90 g          128 t
ORIGIN      
        1 tctaaaaaat ttatgctatt aaatcagtaa tttctgatga attttgaaaa cttaatcccg
       61 tcattcccgc gcaagcggga atccggctcg ttcggtttcg cttgttttaa gtttcgggta
      121 acttccactt cgtcattccc gcgcaggcgg gaatccggtt cattgagttt cagctattta
      181 gaataaattt tgaaactcta atcgcgtcat tcccacgaaa gtgggaatcc aggacgcaaa
      241 atctcaagaa accgttttac ctgataagtt tccgcactga cagacctaga ttcccgcctg
      301 cgcgggaatg acgaatccat ccatacggaa acctgcatcc cgtcattccc acgaaagtgg
      361 gaatccggtt cgttcggttt cgcttgtttt aagtttcggg taacttccac ttcgtcattc
      421 ccacgaaagt gggaatc
//
LOCUS       DAXIDM010000246          430 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.246, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000246 DAXIDM010000000
VERSION     DAXIDM010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.246"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(13..>430)
                     /locus_tag="ACFOAE_002124"
     CDS             complement(13..>430)
                     /locus_tag="ACFOAE_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002222110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFC6885509.1"
                     /translation="TDKVVALLKANGVPAALVDMGEIRGFDTNGKRTWNVGIRNLDDE
                     EGVLANITMKDKAFATSGGYGTVMDKAGRFTHLFDPRTGASTPRYKSMSVMADDAAVA
                     DALSTAFSIMDLPLIRSVAESRRLKVWLVMPDNIVD"
BASE COUNT           95 a          140 c           93 g          102 t
ORIGIN      
        1 tactggtttt tgttaatcca ctatattgtc cggcatgacc agccaaacct taagccgcct
       61 gctttcggca accgaccgta tcaagggcaa atccataatg gaaaacgccg tcgacaaggc
      121 atcggcaacc gccgcatcat ccgccatcac gctcatgctt ttataacgcg gcgtactcgc
      181 gccggtccgc ggatcgaaca aatgggtaaa cctgcccgcc ttgtccatca ccgtcccata
      241 gccgcccgaa gtggcaaacg ccttgtcttt catcgtgata tttgccaaca cgccttcttc
      301 gtcgtccaga ttgcggatgc cgacattcca agtccgttta ccgtttgtat caaatcccct
      361 gatttcgccc atatcgacca gcgcggcagg cacgccgttt gctttaagca gcgcaacaac
      421 cttgtccgtg
//
LOCUS       DAXIDM010000247          426 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000247 DAXIDM010000000
VERSION     DAXIDM010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.247"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(226..>426)
                     /locus_tag="ACFOAE_002125"
     CDS             complement(226..>426)
                     /locus_tag="ACFOAE_002125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFC6885510.1"
                     /translation="GAVSVFSGKYPQAKILLFSQKQKTKNRNLKFVIPTNLHSVIPTK
                     VGIQDAKSQETVLPDKFPHRQT"
BASE COUNT           98 a           77 c          127 g          124 t
ORIGIN      
        1 ggtgcaggtt cgtgggaatg acgtggtgca ggtttccgtg cggatggatt cgtcattccc
       61 gcgcaggcgg gaatctagac attcaatgct aaggcaattt ctcggaaatg actgaaactc
      121 aaaaaactgg attcccactt tcgtgggaat gacgggatat acgtgggaat gacgggatgc
      181 aggtttccgt gcggatggat tcgtcattcc cgcgcaggcg ggaatctagg tctgtcggtg
      241 cggaaactta tcgggtaaaa cggtttcttg agattttgcg tcctggattc ccacttttgt
      301 gggaatgacg gaatgtaggt tcgtgggaat gacgaatttc aggtttctgt ttttggtttt
      361 ctgtttttgt gaaaataaca ggattttagc ttgtgggtat ttaccggaaa aaacagaaac
      421 cgctcc
//
LOCUS       DAXIDM010000248          413 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000248 DAXIDM010000000
VERSION     DAXIDM010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.248"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..247
                     /locus_tag="ACFOAE_002126"
     CDS             <1..247
                     /locus_tag="ACFOAE_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014581020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFC6885511.1"
                     /translation="RCRKCKACRNRPLSEVQTKRNRYLSKTRYVVEQSFGTLHRKFRY
                     ARAAYFGLIKVSAQSHLKAMCLNLLKAANRLSAPVAA"
BASE COUNT          100 a           92 c          130 g           91 t
ORIGIN      
        1 ccgctgtcgg aagtgcaaag cctgccgcaa ccgcccgctg tcggaagtgc aaaccaaacg
       61 caaccgatat ttgtcgaaga cccgttatgt ggttgaacag agcttcggta cgctgcaccg
      121 taaattccgc tacgctcggg cagcctattt cggactgatt aaagtgagtg cgcaaagcca
      181 cctgaaagcg atgtgtttga acctgttgaa agcggccaac aggctaagtg cgcccgttgc
      241 cgcctaaaag gcagcccgga tgcctgatta tcgggtatcc ggggaggatt aagggggtgt
      301 ttgggtagaa ttaggaggta tttggggcga aaacagccga aaacctgtgt ttgggtttcg
      361 gctgtcggga gggaaaggaa ttttgcaaag gtctcggtct gaataatggt ggc
//
LOCUS       DAXIDM010000249          356 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000249 DAXIDM010000000
VERSION     DAXIDM010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.249"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT          113 a           98 c           75 g           70 t
ORIGIN      
        1 aaagcgggaa tctaggacgc agggttaaga aaacctgcat cccgtcattc cctcaaaaac
       61 agaaaaccaa aatcagaaac ctaaaatccc gtcattcccg cataaccgaa acctgacagt
      121 aaccgtagca actgaaccgt cattcccacc acttttcgtc attcccgcga aagcgggaat
      181 ccagaatctc ggactttcag ataatctttg aatattgccg ctgccttaag gtctggattc
      241 ccgcctgcgc gggaatgacg gctgtagatg cccgacggtc tttatagcgg attaacaaaa
      301 atcaggacaa ggcgacgaag ccgcagacag tacaaatagc acggaaccga ttcact
//
LOCUS       DAXIDM010000250          354 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000250 DAXIDM010000000
VERSION     DAXIDM010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.250"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(<1..>354)
                     /locus_tag="ACFOAE_002127"
     CDS             complement(<1..>354)
                     /locus_tag="ACFOAE_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019272253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFC6885512.1"
                     /translation="GDFRTGSVGVTLLDGSRHAPNPVKEIEVARVLQNIGLQSGSTTE
                     AAVRFMLYCMRQQVFWDGNKRTATLFANGLMMAGGCGILEISEMQMPQFNEKLSAFYR
                     SGDDTDISKFVYQNCI"
BASE COUNT           90 a           97 c           82 g           85 t
ORIGIN      
        1 tatacaattt tgatacacaa acttggaaat atcggtatcg tcgccggagc gatagaatgc
       61 ggacagtttt tcattgaatt gcggcatctg catttcggag atttccaaga tgccgcagcc
      121 ccccgccatc atcagaccgt tggcaaataa ggttgccgtt cgtttgttgc cgtcccaaaa
      181 aacctgctgc cgcatacaat aaagcataaa acggacggct gcctccgtcg tcgaaccgct
      241 ttgcagtccg atattttgta acacgcgggc cacttcaatt tccttcactg gattcggggc
      301 atgacgggaa ccgtccaata gcgttacgcc gaccgaaccg gtacggaaat cacc
//
LOCUS       DAXIDM010000251          335 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000251 DAXIDM010000000
VERSION     DAXIDM010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.251"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT          118 a           76 c           75 g           66 t
ORIGIN      
        1 tcagaagtta ctcgaaactt aaaaaaaacg aaatcgaacg gactggattc ccgcctgcgc
       61 gggaatgacg agtcagaagt tactcgaaac ttaaaaaacc gaaatcgaac ggactggatt
      121 cccgcctgcg cgggaatgac gagtcagaag ttactcgaaa cttaaaaaac cgaaatcgaa
      181 cgaattggat ggattcccgc ctgcgcggga atgacgattg atacgtttcg ataatttatt
      241 gaaaatggct gaaatccaaa gttacagaaa tttataaaca aaaaacagca acccgccgcc
      301 gtcattcccg cgaaagcggg aatccagtcc cttga
//
LOCUS       DAXIDM010000252          326 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000252 DAXIDM010000000
VERSION     DAXIDM010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..326
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.252"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT          101 a           83 c           73 g           69 t
ORIGIN      
        1 gggaatctaa aaacccaacg ctgcaaaaat ttatttagaa acaactgaaa ccgctccacc
       61 gtcattcccg cgcaggcggg aatccagtcc gtcgggtaac ggcaatattc aaagattatc
      121 tgaaagtttg aagttctaga ttcccatttt cacgggaatg acgaaaagtt gcaggaatga
      181 cggagtttca ggcggcatcc gaccgcccag tcattcccgc gaaagcggga atctaaaaat
      241 ccaacgctgc aaaaatttat ttagaaacaa ctgaaaccgc tctgccgtca ttcccgtgca
      301 ggcgggaatc cagaccttcg ggtaac
//
LOCUS       DAXIDM010000253          321 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000253 DAXIDM010000000
VERSION     DAXIDM010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.253"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           88 a           76 c           78 g           79 t
ORIGIN      
        1 tgttaatcca ctataaagac cgtcgggcat ctgcagccgt cattcccgcg caggcgagaa
       61 tctagtccgc ttgttcggta aatgagaggg cggattgcgc gcctgtcaga taaaccacgt
      121 gtttaaacgg gcggcaatga ggtacgcgca gagccttgaa gcgcagtcga tatattattt
      181 tccaccaaaa cggacgaccc cgcttgcctt gcaaaccttt aaaaaggaag ccacccggat
      241 taatccgagt ggccgtggaa aatcatttac cgcttgattt atttaaaatt tatggtataa
      301 tttgccttaa acggcagatg a
//
LOCUS       DAXIDM010000254          319 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000254 DAXIDM010000000
VERSION     DAXIDM010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.254"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           70 a           93 c           69 g           87 t
ORIGIN      
        1 ttttgagttt cagtcatttc cgataaattg ccttagcatt gaatgtctag attcccgcct
       61 gcgcgggaat gacggtatcg gtttgtcggc gtttcatttg cccccatccc gaaaacgcaa
      121 acaataccgt ctgaaagctc tgtagggagg gcttcagccc accgattcca tcaatcccac
      181 atttccgccg ttttcaccga atccgcccct tttcacaatc cagtcctacg caactgaacc
      241 gtcattcccg cgcaggcggg aatccggact tgtcggcacg gaaacttatc gggtacaacg
      301 gtttcttgag attttacgt
//
LOCUS       DAXIDM010000255          319 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.255, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000255 DAXIDM010000000
VERSION     DAXIDM010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.255"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           86 a           62 c           86 g           85 t
ORIGIN      
        1 tttttgacac attttcatga tttcaaatcc cgttattccc aagtggacgg aaacccgata
       61 atgggaagcc gcagagactt atcgggaaaa cggcaagccc tccgccgtca ttcccgcgca
      121 ggcgggaatc tagaaataaa aaaccacggt gttatcggca atgactgaaa ccggagaaat
      181 gacgaaattg aagcgtgcgg aaatgtgtcg gaaatcgctg aagccggata aactagattc
      241 ccgcttttgc gggaatgacg ggattttagg tttttggttt gttttcgcgg caatgatggg
      301 attttaggtt tttggtttg
//
LOCUS       DAXIDM010000256          317 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.256, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000256 DAXIDM010000000
VERSION     DAXIDM010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..317
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.256"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            64..>317
                     /locus_tag="ACFOAE_002128"
     CDS             64..>317
                     /locus_tag="ACFOAE_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017201170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFC6885513.1"
                     /translation="MKDKKMNIIDTAIPDVKLLEPQVFGDARGFFMETFRDEWFKTQV
                     CERTFVQENHSKSGKGVLRGLHYQTENTQGKLVRVVVGEV"
BASE COUNT           91 a           81 c           73 g           72 t
ORIGIN      
        1 tttgctgcgc ctgttgaaaa aataatgttt gaggccgtct gaaacttttc agacggcctt
       61 tagatgaaag ataaaaagat gaacatcatt gataccgcca ttcctgacgt aaaactgctt
      121 gagccccaag tcttcggcga cgcgcgcggc ttttttatgg aaaccttccg cgacgagtgg
      181 tttaaaaccc aagtctgcga acgcaccttc gtgcaggaaa accactccaa atccggcaaa
      241 ggcgtattgc gcggcctgca ctaccaaacc gaaaacacac aaggcaaact cgtacgcgta
      301 gttgtcggcg aagtatt
//
LOCUS       DAXIDM010000257          308 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000257 DAXIDM010000000
VERSION     DAXIDM010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.257"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           76 a           82 c           64 g           86 t
ORIGIN      
        1 agtggattaa atttatagtg gattaacaaa aaccagtaca gcgttggctc gccttagctc
       61 aaagagaacg attctctaag gtgctgaagc accaagtgaa tcggttccgt actatctgta
      121 ctgtctgcgg cttcgccgcc ttgtcccgat ttttgttaat cctctatacc atgtcaattc
      181 agcctttatt tcgcgagcaa agcccacgct acacccactt tccagaagta cattaggctg
      241 ccactccgac aaagccgttt gattccgcaa actgtcgggg ttcgccacaa tctacggcta
      301 ctgtgttg
//
LOCUS       DAXIDM010000258          277 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000258 DAXIDM010000000
VERSION     DAXIDM010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.258"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            complement(19..234)
                     /locus_tag="ACFOAE_002129"
                     /pseudo
     CDS             complement(19..234)
                     /locus_tag="ACFOAE_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           94 a           54 c           48 g           81 t
ORIGIN      
        1 aaatctgaat ttgagattct atttaaaatg ccattggcat ttctttaaat gcagccccaa
       61 atgctctttg ggaatgccgt taaacttacg taaatggcta aattcactaa tatcaagcac
      121 atcataacta cgaaaggtat ccgtgtatac aatgccatca ggcttaactt tctttcggat
      181 aattggcaac aatgtcgctg attgcgcatt aggaacaacg acggtataaa ccttatatat
      241 tgcgtcccta agaagggacg attaacaaaa attaacg
//
LOCUS       DAXIDM010000259          277 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000259 DAXIDM010000000
VERSION     DAXIDM010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.259"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..>277
                     /locus_tag="ACFOAE_002130"
     CDS             <1..>277
                     /locus_tag="ACFOAE_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002249609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF637 domain-containing protein"
                     /protein_id="HFC6885514.1"
                     /translation="ALAVTVVTSGAGTGAVLGLNGAAAAATDAAFASLASQASVSFIN
                     NKGDVGKTLKELGRSSTVKNLVVAAATAGVADKIGASALNNVSDKQW"
BASE COUNT           67 a           80 c           82 g           48 t
ORIGIN      
        1 tcgcactggc cgttaccgtg gtcacctcag gcgcaggaac cggagccgta ttgggattaa
       61 acggtgcggc cgccgccgca accgatgcag cattcgcctc tttggccagc caggcttccg
      121 tatcgttcat caacaacaaa ggcgatgtcg gcaaaaccct gaaagagctg ggcagaagca
      181 gcacggtgaa aaatctggtg gttgccgccg ctaccgcagg cgtagccgac aaaatcggcg
      241 cttcggcact gaacaatgtc agcgataagc agtggat
//
LOCUS       DAXIDM010000260          269 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.260, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000260 DAXIDM010000000
VERSION     DAXIDM010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.260"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           91 a           39 c           47 g           92 t
ORIGIN      
        1 cgaaaaaacg cgacgtaacc agcatcaaca tatataagaa cagcacaaat agcatcaata
       61 catcaggcaa cgaaaatgca gaataatgca cttaatggtg tttggatatc tgttgttttg
      121 tgctgttagt aattcttctt tctgtgttta cagtttagca gttgtacagt tttacagtaa
      181 tgtttaaaca atgactgatt tattttaaat gcagatattg tagaggataa aaatggccaa
      241 agtcctttca gtaacatttt tgatttttt
//
LOCUS       DAXIDM010000261          269 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000261 DAXIDM010000000
VERSION     DAXIDM010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.261"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            1..264
                     /locus_tag="ACFOAE_002131"
                     /pseudo
     CDS             1..264
                     /locus_tag="ACFOAE_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002247434.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT           89 a           66 c           52 g           62 t
ORIGIN      
        1 ttctaccaac acaccaaaat aaccaaagca ttgaaagcgg agacttattt ttgtcgccct
       61 tagcattctt gggagaaagg gctgaatgag aacaccaacg gactcatccg gcaatacttc
      121 cccaaacaaa ccgatttccg taacatcagt gatcgggaga tacgcagggt tcaagatgag
      181 ttgaaccacc gaccaagaaa aacacttggc tacgaaacgc caagtgtttt attcttgaat
      241 ctgttccaac cactaataca ctagtgttg
//
LOCUS       DAXIDM010000262          243 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000262 DAXIDM010000000
VERSION     DAXIDM010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.262"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
     gene            <1..98
                     /locus_tag="ACFOAE_002132"
     CDS             <1..98
                     /locus_tag="ACFOAE_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016686572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HFC6885515.1"
                     /translation="WLATRDSRDFYDVLNEALSAASGEAVEIEEL"
     gene            125..>243
                     /locus_tag="ACFOAE_002133"
     CDS             125..>243
                     /locus_tag="ACFOAE_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002256967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HFC6885516.1"
                     /translation="MNTRPFYFGLIFIAIIAILANYLGNTDFSHHYHISALIIA"
BASE COUNT           67 a           44 c           54 g           78 t
ORIGIN      
        1 aatggctggc aacgcgagac agccgcgatt tttatgatgt tttaaacgaa gccctgagcg
       61 cggcttcggg cgaagcggta gagattgagg aattgtgatt tgggtgttat cacggaaaga
      121 aaaaatgaac acacgtccct tttatttcgg acttatattt atcgcgatta ttgctatact
      181 tgctaactat ttaggaaaca ctgatttttc ccatcattat catatcagtg ctttaattat
      241 tgc
//
LOCUS       DAXIDM010000263          232 bp    DNA     linear   BCT 02-OCT-2024
DEFINITION  TPA_asm: Neisseria meningitidis isolate 23ME000009
            SAMEA112890786-rid22929503.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DAXIDM010000263 DAXIDM010000000
VERSION     DAXIDM010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112890786
            Sequence Read Archive: ERR11218502
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Neisseria meningitidis
  ORGANISM  Neisseria meningitidis
            Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
            Neisseriaceae; Neisseria.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 20-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002330825.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002330825.1
            Genome Coverage       :: 392x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/28/2024 09:19:11
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,076
            Genes (coding)                    :: 1,933
            CDSs (with protein)               :: 1,933
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 49
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 143
            CDSs (without protein)            :: 143
            Pseudo Genes (ambiguous residues) :: 0 of 143
            Pseudo Genes (frameshifted)       :: 53 of 143
            Pseudo Genes (incomplete)         :: 93 of 143
            Pseudo Genes (internal stop)      :: 16 of 143
            Pseudo Genes (multiple problems)  :: 19 of 143
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Neisseria meningitidis"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112890786-rid22929503.denovo.263"
                     /isolate="23ME000009"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:487"
                     /geo_loc_name="Norway"
                     /collection_date="2023"
BASE COUNT           58 a           50 c           53 g           71 t
ORIGIN      
        1 cactccgtca ttcccacgaa agtgggaatc cagttttttg agtttcagtc attcccgaga
       61 aattgcctta gcattgaatg tctagattcc cgcctgcgcg ggaatgacgg gattttaagt
      121 tggggtcatt tattggaaaa agcagaaacc gctccgccgt cattcccacg aaagtgggaa
      181 tccagttttt tgagtttcag tcatttccga taaattgcct tagtattgaa tg
//
